# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- rve PF00665.26 KRH91712.1 - 3.5e-17 62.7 0.0 4.5e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH91712.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KRH91714.1 - 5.5e-10 39.1 0.3 8.2e-10 38.6 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Carboxyl_trans PF01039.22 KRH91716.1 - 8.6e-13 47.7 0.0 1e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain WD40 PF00400.32 KRH91717.1 - 4.9e-07 30.4 0.4 9.5e-05 23.1 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH91717.1 - 0.027 14.8 0.0 7.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb1_4 PF05000.17 KRH91718.1 - 2.8e-27 94.8 0.2 4.7e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 KRH91718.1 - 3.4e-27 95.6 0.1 4.3e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Toprim PF01751.22 KRH91719.1 - 7.9e-21 74.2 0.1 1e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 KRH91719.1 - 0.0019 18.7 0.0 0.0032 17.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain SYCP2_ARLD PF18581.1 KRH91719.1 - 0.016 15.2 0.7 0.021 14.8 0.7 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain Toprim_2 PF13155.6 KRH91719.1 - 0.027 14.9 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 Toprim-like DUF3835 PF12927.7 KRH91719.1 - 0.029 15.2 0.1 0.045 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) UDPGP PF01704.18 KRH91721.1 - 3.3e-10 39.2 0.2 3.3e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase AROS PF15684.5 KRH91721.1 - 0.032 14.8 1.6 0.06 13.9 0.1 1.9 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 NTP_transf_3 PF12804.7 KRH91721.1 - 0.16 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain DEAD PF00270.29 KRH91722.1 - 7.3e-08 32.4 0.0 9.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH91722.1 - 0.012 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit gag-asp_proteas PF13975.6 KRH91723.1 - 1.3e-05 25.7 0.0 1.9e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KRH91723.1 - 0.0013 18.5 0.1 0.0042 16.9 0.1 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH91723.1 - 0.003 17.3 0.2 0.004 16.9 0.2 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH91723.1 - 0.02 15.5 0.0 0.039 14.6 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease RNA_pol_Rpb2_6 PF00562.28 KRH91724.1 - 1e-19 70.9 0.3 1e-19 70.9 0.3 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 VlpA_repeat PF04649.12 KRH91724.1 - 2.1 8.7 4.0 4.9e+02 1.4 0.0 4.5 4 0 0 4 4 4 0 Mycoplasma hyorhinis VlpA repeat RVT_1 PF00078.27 KRH91725.1 - 3.2e-10 39.9 0.0 3.6e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2846 PF11008.8 KRH91726.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) Sld5 PF05916.11 KRH91726.1 - 0.078 13.4 1.0 0.16 12.5 0.6 1.7 1 1 1 2 2 2 0 GINS complex protein DUF4258 PF14076.6 KRH91730.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) PSP1 PF04468.12 KRH91731.1 - 9.3e-25 86.7 4.3 1.3e-24 86.2 4.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-GRF PF06839.12 KRH91733.1 - 1.9e-12 47.0 12.7 4.6e-12 45.8 4.1 2.2 2 0 0 2 2 2 2 GRF zinc finger Jiv90 PF14901.6 KRH91733.1 - 0.0095 16.1 0.8 0.013 15.7 0.8 1.2 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone zf-CCHC PF00098.23 KRH91734.1 - 0.00012 22.0 0.8 0.00012 22.0 0.8 1.6 2 0 0 2 2 2 1 Zinc knuckle ATP_bind_1 PF03029.17 KRH91735.1 - 5.1e-28 98.5 0.2 2.3e-27 96.4 0.2 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KRH91735.1 - 0.01 15.5 0.2 0.015 15.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KRH91735.1 - 0.029 14.5 0.5 0.11 12.5 0.5 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KRH91735.1 - 0.03 14.5 0.0 0.054 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KRH91735.1 - 0.051 13.9 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.22 KRH91736.1 - 2.6e-14 52.8 0.0 2.8e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DUF658 PF04936.12 KRH91736.1 - 0.019 14.7 0.5 0.023 14.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) RPEL PF02755.15 KRH91736.1 - 7.7 6.4 8.6 14 5.5 0.3 3.5 3 0 0 3 3 3 0 RPEL repeat ER_lumen_recept PF00810.18 KRH91737.1 - 9.1e-09 36.3 2.3 9.1e-09 36.3 2.3 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KRH91737.1 - 0.0016 18.2 7.0 0.043 13.6 2.0 2.7 1 1 1 2 2 2 2 PQ loop repeat Ribosomal_L3 PF00297.22 KRH91738.1 - 2.3e-15 56.4 0.2 2.5e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 RVT_1 PF00078.27 KRH91739.1 - 2.9e-31 108.7 0.5 3.6e-31 108.4 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH91740.1 - 1.4e-32 113.0 0.6 1.8e-32 112.7 0.6 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.31 KRH91741.1 - 3.7e-05 24.0 0.9 0.0006 20.1 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain Peptidase_M85 PF13678.6 KRH91741.1 - 0.0012 18.5 1.1 0.0055 16.3 0.0 1.9 1 1 1 2 2 2 1 NFkB-p65-degrading zinc protease DUF1690 PF07956.11 KRH91741.1 - 0.021 15.3 0.7 0.027 14.9 0.7 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) ZIP4_domain PF18292.1 KRH91741.1 - 0.17 11.8 1.1 0.66 9.9 0.6 1.7 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain HSF_DNA-bind PF00447.17 KRH91742.1 - 8.3e-13 48.8 0.2 1.7e-12 47.8 0.1 1.5 1 1 0 1 1 1 1 HSF-type DNA-binding tRNA-synt_His PF13393.6 KRH91743.1 - 1.5e-15 57.2 0.0 1.9e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 KRH91743.1 - 0.00032 20.7 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KRH91743.1 - 0.0063 16.0 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Spt4 PF06093.13 KRH91744.1 - 5.1e-09 36.1 0.2 7.9e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger rve PF00665.26 KRH91747.1 - 1.2e-08 35.2 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain TFIIS_C PF01096.18 KRH91748.1 - 3.2e-16 58.9 9.8 3.2e-16 58.9 9.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KRH91748.1 - 0.00046 20.0 4.1 0.00046 20.0 4.1 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KRH91748.1 - 0.0028 18.0 7.5 0.0066 16.8 0.0 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.8 KRH91748.1 - 0.022 14.4 0.5 0.022 14.4 0.5 3.1 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain PHD PF00628.29 KRH91748.1 - 1.4 8.9 14.6 0.32 10.9 0.8 2.7 2 1 0 2 2 2 0 PHD-finger zf-WRNIP1_ubi PF18279.1 KRH91748.1 - 3.5 8.5 7.8 4.4 8.2 0.1 3.3 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain AsnA PF03590.15 KRH91751.1 - 4.8e-48 163.9 1.1 5.5e-48 163.7 1.1 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase AsnA PF03590.15 KRH91752.1 - 1.4e-48 165.6 1.2 1.6e-48 165.4 1.2 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase rve PF00665.26 KRH91753.1 - 1.1e-06 28.8 0.1 1.8e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH91753.1 - 0.0047 16.7 0.1 0.017 14.9 0.1 2.1 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_1_2 PF13586.6 KRH91753.1 - 0.086 13.2 0.5 0.2 12.1 0.1 1.8 1 1 1 2 2 2 0 Transposase DDE domain rve PF00665.26 KRH91754.1 - 4.6e-06 26.8 0.1 7.3e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain BOF PF04076.13 KRH91754.1 - 0.02 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein rve_3 PF13683.6 KRH91754.1 - 0.032 14.0 0.1 0.088 12.6 0.1 1.9 1 1 0 1 1 1 0 Integrase core domain DDE_Tnp_1_2 PF13586.6 KRH91754.1 - 0.066 13.6 0.4 0.15 12.4 0.1 1.7 1 1 1 2 2 2 0 Transposase DDE domain Phage-tail_2 PF09096.10 KRH91754.1 - 0.075 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 DUF1344 PF07076.11 KRH91754.1 - 0.089 12.7 0.2 0.66 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Hva1_TUDOR PF11160.8 KRH91754.1 - 0.13 12.5 0.1 5.6 7.2 0.1 2.6 2 1 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain GCS PF03074.16 KRH91755.1 - 1.1e-26 94.1 2.2 1.3e-26 93.9 2.2 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase RVT_1 PF00078.27 KRH91757.1 - 3.2e-16 59.5 0.1 4.4e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SmpB PF01668.18 KRH91757.1 - 0.026 14.4 2.6 0.035 14.0 2.6 1.1 1 0 0 1 1 1 0 SmpB protein TAN PF11640.8 KRH91757.1 - 0.06 13.5 0.3 0.085 13.0 0.3 1.2 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF3006 PF11213.8 KRH91757.1 - 0.17 12.2 1.9 0.2 11.9 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) SCAN PF02023.17 KRH91758.1 - 0.022 14.6 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 SCAN domain SCAN PF02023.17 KRH91759.1 - 0.06 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 SCAN domain RNA_pol_Rpb2_1 PF04563.15 KRH91760.1 - 2e-07 30.8 0.0 2.3e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase beta subunit RVT_1 PF00078.27 KRH91761.1 - 1.5e-23 83.5 0.9 2e-23 83.1 0.9 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G PF03179.15 KRH91762.1 - 0.00013 22.4 8.5 0.00028 21.4 8.2 1.7 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YrzO PF14142.6 KRH91762.1 - 0.061 13.2 0.6 0.061 13.2 0.6 1.9 2 0 0 2 2 2 0 YrzO-like protein PrmC_N PF17827.1 KRH91762.1 - 0.071 13.7 1.4 0.1 13.2 1.4 1.3 1 1 0 1 1 1 0 PrmC N-terminal domain DUF3055 PF11256.8 KRH91762.1 - 0.11 12.8 1.6 0.17 12.2 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3055) DUF4956 PF16316.5 KRH91762.1 - 0.26 10.9 1.1 0.29 10.8 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Peptidase_M16 PF00675.20 KRH91764.1 - 9e-08 32.2 0.0 9.4e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16 PF00675.20 KRH91765.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-C4_Topoisom PF01396.19 KRH91766.1 - 0.0068 16.2 2.3 0.01 15.6 2.3 1.4 1 1 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.16 KRH91766.1 - 0.0082 16.2 2.6 0.015 15.3 2.6 1.5 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 KRH91766.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 KRH91766.1 - 0.014 15.4 1.0 0.028 14.5 1.0 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Elf1 PF05129.13 KRH91766.1 - 0.025 14.6 0.7 0.029 14.4 0.7 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PapB PF03333.13 KRH91766.1 - 0.026 14.5 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein AvrM_N PF18247.1 KRH91770.1 - 0.0073 16.2 0.6 0.035 14.0 0.1 2.3 2 1 0 2 2 2 1 Flax-rust effector AvrM N-terminal domain ExsD PF16806.5 KRH91771.1 - 0.052 13.5 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Antiactivator protein ExsD AvrM_N PF18247.1 KRH91771.1 - 0.099 12.6 2.1 0.23 11.4 0.1 2.5 3 1 0 3 3 3 0 Flax-rust effector AvrM N-terminal domain RVT_1 PF00078.27 KRH91772.1 - 7.4e-20 71.4 0.5 1e-19 70.9 0.1 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) UL41A PF17591.2 KRH91772.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A RVT_1 PF00078.27 KRH91773.1 - 7.3e-32 110.7 0.2 9.1e-32 110.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KRH91773.1 - 0.058 13.0 0.1 0.74 9.4 0.0 2.0 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) CutC PF03932.14 KRH91774.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 CutC family DUF3048 PF11258.8 KRH91774.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain RT_RNaseH_2 PF17919.1 KRH91775.1 - 8.1e-17 61.1 0.0 9.5e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH91775.1 - 6.3e-09 36.1 0.0 9.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1229 PF06797.11 KRH91775.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) MTS PF05175.14 KRH91776.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Flavodoxin_1 PF00258.25 KRH91777.1 - 6.7e-21 75.0 0.0 8.2e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin DUF3634 PF12321.8 KRH91777.1 - 0.017 15.5 0.1 0.027 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3634) LRR_8 PF13855.6 KRH91778.1 - 1e-20 73.3 54.5 1.2e-07 31.4 13.3 4.7 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KRH91778.1 - 5e-18 64.9 43.4 3.9e-08 33.4 1.4 4.4 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KRH91778.1 - 9.4e-06 25.2 18.4 0.0043 16.6 0.7 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KRH91778.1 - 0.00012 22.1 29.4 0.94 10.3 0.3 6.9 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.6 KRH91778.1 - 0.0014 18.5 25.0 0.32 11.1 0.1 6.8 6 1 0 6 6 6 3 Leucine Rich repeat HC2 PF07382.11 KRH91779.1 - 0.12 12.4 37.2 0.16 12.1 37.2 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 BCD PF15461.6 KRH91780.1 - 0.0096 15.4 1.3 0.01 15.3 1.3 1.0 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase DUF1700 PF08006.11 KRH91780.1 - 0.12 11.9 1.6 0.14 11.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) TAFII28 PF04719.14 KRH91781.1 - 5.3e-32 109.8 0.0 8.4e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region FbpA PF05833.11 KRH91781.1 - 0.045 12.5 5.0 0.49 9.1 0.0 2.1 1 1 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) AAA_lid_1 PF17857.1 KRH91781.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA+ lid domain V_cholerae_RfbT PF05575.11 KRH91782.1 - 0.00021 20.7 1.0 0.00024 20.5 1.0 1.0 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein rve PF00665.26 KRH91783.1 - 1.7e-19 70.2 0.0 2.5e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KRH91783.1 - 0.0028 17.5 4.1 0.0041 16.9 2.9 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Phage_integr_3 PF16795.5 KRH91783.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Archaeal phage integrase Integrase_H2C2 PF17921.1 KRH91783.1 - 0.027 14.6 1.6 0.088 12.9 1.6 1.9 1 1 0 1 1 1 0 Integrase zinc binding domain rve_3 PF13683.6 KRH91783.1 - 0.027 14.2 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Ribosomal_L31e PF01198.19 KRH91784.1 - 1.6e-11 44.3 0.8 2e-11 43.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_S30 PF04758.14 KRH91785.1 - 1.1e-14 54.3 4.5 1.6e-14 53.8 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 RNF111_N PF15303.6 KRH91785.1 - 0.59 9.9 3.3 0.59 9.9 3.3 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus ER_lumen_recept PF00810.18 KRH91786.1 - 9.1e-09 36.3 2.3 9.1e-09 36.3 2.3 1.7 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KRH91786.1 - 0.0016 18.2 7.0 0.043 13.6 2.0 2.7 1 1 1 2 2 2 2 PQ loop repeat Tim17 PF02466.19 KRH91787.1 - 5.9e-10 39.5 3.4 2.7e-09 37.4 3.4 1.8 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3493 PF11998.8 KRH91787.1 - 0.13 12.4 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF2040 PF09745.9 KRH91788.1 - 0.0072 16.4 1.0 0.0089 16.1 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) DFRP_C PF16543.5 KRH91788.1 - 1.2 9.7 8.8 1.7 9.2 8.2 1.7 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Swi5 PF07061.11 KRH91789.1 - 2.3e-16 59.6 1.1 2.3e-16 59.6 1.1 1.7 2 0 0 2 2 2 1 Swi5 Kinesin PF00225.23 KRH91790.1 - 1.5e-27 96.4 0.1 1.5e-27 96.4 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain DDE_Tnp_IS1595 PF12762.7 KRH91791.1 - 1.4e-13 51.1 0.0 1.5e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.6 KRH91791.1 - 0.011 15.9 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 0 DDE domain Beta-TrCP_D PF12125.8 KRH91791.1 - 0.15 12.0 0.4 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 D domain of beta-TrCP Na_H_Exchanger PF00999.21 KRH91792.1 - 7.5e-07 28.3 2.1 9e-07 28.0 2.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5589 PF17672.1 KRH91792.1 - 0.31 11.0 1.4 0.63 10.0 1.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5589) Sel1 PF08238.12 KRH91793.1 - 4.1 8.2 8.6 0.24 12.1 1.9 2.5 3 0 0 3 3 3 0 Sel1 repeat RNA_pol_L PF01193.24 KRH91795.1 - 0.2 11.1 0.2 0.27 10.7 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain PUF PF00806.19 KRH91796.1 - 0.0011 18.6 0.5 0.041 13.6 0.1 3.3 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat RINGv PF12906.7 KRH91797.1 - 7e-11 42.1 8.9 1.3e-10 41.3 8.9 1.4 1 0 0 1 1 1 1 RING-variant domain DUF2274 PF10038.9 KRH91798.1 - 0.087 13.3 0.1 0.6 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2274) Ribosomal_L7Ae PF01248.26 KRH91799.1 - 4.1e-15 55.3 0.0 4.9e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GTP-bdg_N PF13167.6 KRH91799.1 - 0.12 13.1 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal CSD PF00313.22 KRH91800.1 - 0.041 13.7 0.5 0.1 12.5 0.5 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF5601 PF18151.1 KRH91802.1 - 0.0029 17.9 1.2 0.005 17.1 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Fib_alpha PF08702.10 KRH91802.1 - 0.014 15.6 0.7 0.017 15.3 0.7 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5113 PF17140.4 KRH91802.1 - 0.02 14.7 0.2 0.025 14.4 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) ASCH PF04266.14 KRH91802.1 - 0.021 15.4 1.0 0.92 10.1 1.0 2.1 1 1 0 1 1 1 0 ASCH domain CHCH PF06747.13 KRH91802.1 - 0.055 13.6 2.2 0.75 10.0 0.5 2.3 2 0 0 2 2 2 0 CHCH domain ApoO PF09769.9 KRH91802.1 - 0.067 13.2 0.7 2.7 8.0 0.4 2.0 1 1 1 2 2 2 0 Apolipoprotein O CREPT PF16566.5 KRH91802.1 - 0.1 12.8 2.2 0.11 12.6 2.2 1.0 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RT_RNaseH_2 PF17919.1 KRH91803.1 - 6.3e-14 51.8 0.0 6.9e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH91803.1 - 4.5e-13 49.4 0.0 4.6e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH91804.1 - 3.9e-30 103.8 0.0 6.2e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH91804.1 - 1.3e-22 80.0 0.0 2.8e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EIF_2_alpha PF07541.12 KRH91804.1 - 0.017 15.2 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit AAA_lid_3 PF17862.1 KRH91805.1 - 5.7e-07 29.2 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 AAA+ lid domain RNA_pol_Rpb2_6 PF00562.28 KRH91809.1 - 9.5e-07 28.2 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 KapB PF08810.10 KRH91809.1 - 0.00029 21.0 0.8 0.22 11.7 0.0 2.5 1 1 1 2 2 2 2 Kinase associated protein B Sec3_C_2 PF15278.6 KRH91809.1 - 0.0016 18.8 3.6 0.4 11.1 0.1 2.5 1 1 1 2 2 2 2 Sec3 exocyst complex subunit ApoLp-III PF07464.11 KRH91809.1 - 0.0097 16.0 2.4 5.2 7.2 0.0 2.3 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KRH91809.1 - 0.061 11.3 0.2 0.064 11.2 0.2 1.1 1 0 0 1 1 1 0 Prominin PIN_8 PF18476.1 KRH91809.1 - 0.064 13.1 3.7 0.13 12.1 3.7 1.5 1 1 0 1 1 1 0 PIN like domain Exonuc_VII_L PF02601.15 KRH91809.1 - 0.52 9.8 4.5 0.64 9.5 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YojJ PF10372.9 KRH91809.1 - 0.53 10.4 2.5 6.4 6.9 0.1 2.8 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus Prefoldin_2 PF01920.20 KRH91809.1 - 0.64 10.0 6.9 1.2 9.2 1.4 2.6 1 1 0 2 2 2 0 Prefoldin subunit PRKCSH-like PF12999.7 KRH91809.1 - 0.85 9.4 5.7 0.82 9.4 2.7 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like FliE PF02049.18 KRH91809.1 - 1.8 8.7 4.5 24 5.1 1.2 2.4 1 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE LURAP PF14854.6 KRH91809.1 - 3.4 7.6 13.3 14 5.7 3.3 2.5 1 1 1 2 2 2 0 Leucine rich adaptor protein Bravo_FIGEY PF13882.6 KRH91809.1 - 8.7 7.8 14.7 5.8 8.4 0.9 3.1 1 1 2 3 3 3 0 Bravo-like intracellular region AMP-binding PF00501.28 KRH91811.1 - 3.1e-19 68.9 0.8 3.7e-10 39.0 0.1 2.0 2 0 0 2 2 2 2 AMP-binding enzyme DDE_3 PF13358.6 KRH91812.1 - 0.0014 18.4 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KRH91813.1 - 4.8e-14 52.4 0.0 5.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.25 KRH91814.1 - 3.3e-20 72.6 0.0 3.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH91814.1 - 2.7e-07 30.1 0.0 4.3e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase DDE_3 PF13358.6 KRH91815.1 - 6.5e-24 84.4 0.0 7.6e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KRH91815.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease LNS2 PF08235.13 KRH91816.1 - 8.3e-13 48.3 0.1 1.5e-12 47.5 0.1 1.5 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) V_ATPase_I PF01496.19 KRH91817.1 - 2.7e-07 28.9 1.1 3.3e-07 28.7 1.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LytTR PF04397.15 KRH91817.1 - 0.0031 17.7 0.1 0.0054 16.9 0.1 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain PI_PP_I PF18363.1 KRH91817.1 - 0.0041 17.3 0.9 0.0067 16.6 0.9 1.4 1 0 0 1 1 1 1 Phosphoinositide phosphatase insertion domain DUF929 PF06053.11 KRH91817.1 - 0.027 13.8 0.4 0.043 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Virulence_RhuM PF13310.6 KRH91817.1 - 0.037 13.3 1.7 0.057 12.7 1.5 1.4 1 1 0 1 1 1 0 Virulence protein RhuM family Cdh1_DBD_1 PF18196.1 KRH91817.1 - 0.32 11.3 5.1 0.39 11.0 0.1 2.3 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 TAF8_C PF10406.9 KRH91818.1 - 3.4e-11 43.5 0.4 3.4e-11 43.5 0.4 2.6 2 1 1 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term SLC12 PF03522.15 KRH91818.1 - 0.2 10.6 8.3 0.26 10.3 8.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 KRH91818.1 - 0.27 9.5 12.5 0.28 9.4 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KRH91818.1 - 0.27 9.3 8.4 0.28 9.3 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PI3K_1B_p101 PF10486.9 KRH91818.1 - 0.27 9.0 6.8 0.27 9.0 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 KRH91818.1 - 0.47 9.2 6.8 0.52 9.0 6.8 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 KRH91818.1 - 1.4 7.7 8.8 1.4 7.7 8.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Paramyxo_ncap PF00973.19 KRH91818.1 - 1.7 7.5 7.9 2.1 7.2 7.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mem_trans PF03547.18 KRH91818.1 - 1.7 6.9 3.2 1.8 6.8 3.2 1.2 1 0 0 1 1 1 0 Membrane transport protein ALMT PF11744.8 KRH91818.1 - 4.8 5.9 7.8 7.5 5.3 7.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter rve PF00665.26 KRH91819.1 - 3.9e-15 56.1 0.0 4.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH91822.1 - 2.7e-06 27.4 1.4 1.1e-05 25.4 1.4 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain Zn_ribbon_17 PF17120.5 KRH91822.1 - 0.0037 16.9 0.3 0.0061 16.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-XS PF03470.14 KRH91822.1 - 0.24 11.7 0.9 0.45 10.8 0.9 1.5 1 0 0 1 1 1 0 XS zinc finger domain DDE_3 PF13358.6 KRH91823.1 - 1.9e-10 40.6 0.1 2.4e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 KRH91823.1 - 0.0085 16.3 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Bromodomain PF00439.25 KRH91823.1 - 0.019 15.0 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Bromodomain rve PF00665.26 KRH91825.1 - 9.2e-12 45.2 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH91825.1 - 0.00094 19.2 1.9 0.0035 17.4 1.9 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain zf-XS PF03470.14 KRH91825.1 - 0.068 13.4 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 XS zinc finger domain RdRP PF05183.12 KRH91826.1 - 1.5e-36 126.3 0.1 3e-35 121.9 0.1 2.0 1 1 0 1 1 1 1 RNA dependent RNA polymerase DNA_gyraseB PF00204.25 KRH91827.1 - 4.6e-08 32.7 0.2 1.1e-07 31.5 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase B rve PF00665.26 KRH91828.1 - 0.00048 20.3 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KRH91829.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain GCS PF03074.16 KRH91830.1 - 2.6e-07 30.4 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase zinc-ribbons_6 PF07191.12 KRH91831.1 - 0.18 11.8 5.9 5 7.2 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbons zf-Nse PF11789.8 KRH91832.1 - 1.5e-10 40.7 1.1 2.8e-10 39.8 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit MapZ_EC1 PF18041.1 KRH91832.1 - 0.015 15.5 3.1 0.021 15.0 3.1 1.3 1 1 0 1 1 1 0 MapZ extracellular domain 1 NUC PF18510.1 KRH91832.1 - 0.059 13.8 0.3 0.074 13.5 0.3 1.1 1 0 0 1 1 1 0 Nuclease domain zf-RING_2 PF13639.6 KRH91832.1 - 0.08 13.3 2.0 0.14 12.5 2.0 1.5 1 0 0 1 1 1 0 Ring finger domain RVT_1 PF00078.27 KRH91834.1 - 4.4e-14 52.5 0.1 4.8e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AD PF09793.9 KRH91834.1 - 0.072 13.2 1.0 0.15 12.2 0.3 1.7 1 1 1 2 2 2 0 Anticodon-binding domain EFG_C PF00679.24 KRH91835.1 - 0.002 18.1 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus WD40 PF00400.32 KRH91836.1 - 8.9e-08 32.7 0.0 0.016 16.1 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat GRAM PF02893.20 KRH91837.1 - 0.005 16.7 0.1 0.0072 16.2 0.1 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KRH91837.1 - 0.015 15.5 1.4 0.02 15.1 0.0 2.1 2 1 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 RVT_1 PF00078.27 KRH91838.1 - 2.3e-26 92.7 0.2 3.4e-26 92.2 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1800 PF08811.11 KRH91838.1 - 0.026 13.5 0.0 0.067 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1800) zf-CCHC PF00098.23 KRH91840.1 - 8.1e-08 32.0 11.0 2.2e-05 24.3 2.1 5.8 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_2 PF13696.6 KRH91840.1 - 0.0057 16.4 4.3 0.0057 16.4 4.3 5.1 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_4 PF14392.6 KRH91840.1 - 2.5 7.9 36.7 0.2 11.4 1.0 4.6 3 1 2 5 5 5 0 Zinc knuckle rve PF00665.26 KRH91841.1 - 2.5e-09 37.4 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RNA_pol_Rpb2_6 PF00562.28 KRH91843.1 - 5e-22 78.5 0.1 5.9e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 KRH91843.1 - 1.6e-19 70.0 0.4 3e-19 69.2 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 MAD PF05557.13 KRH91844.1 - 3.5e-10 38.9 14.9 1.8e-09 36.6 14.9 1.8 1 1 0 1 1 1 1 Mitotic checkpoint protein Cnn_1N PF07989.11 KRH91844.1 - 1.8e-06 28.0 13.8 3.1e-06 27.2 13.8 1.5 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 YlqD PF11068.8 KRH91844.1 - 0.012 15.9 9.2 0.016 15.6 9.2 1.2 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.19 KRH91844.1 - 0.017 13.1 6.7 0.017 13.0 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myosin_tail_1 PF01576.19 KRH91844.1 - 0.018 12.9 8.5 0.021 12.7 8.5 1.0 1 0 0 1 1 1 0 Myosin tail IFP_35_N PF07334.13 KRH91844.1 - 0.34 11.0 6.7 0.31 11.1 5.0 1.8 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Uso1_p115_C PF04871.13 KRH91844.1 - 0.36 11.2 9.6 0.49 10.8 9.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PdaC PF13739.6 KRH91844.1 - 1 10.4 7.1 1.6 9.7 7.1 1.3 1 0 0 1 1 1 0 Deacetylase PdaC DivIVA PF05103.13 KRH91844.1 - 1.6 8.8 11.0 0.23 11.5 2.6 2.2 1 1 1 2 2 2 0 DivIVA protein YabA PF06156.13 KRH91844.1 - 8.4 7.1 11.9 2 9.1 4.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA RVT_1 PF00078.27 KRH91845.1 - 7.5e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prenylcys_lyase PF07156.14 KRH91845.1 - 0.033 13.3 0.6 0.048 12.8 0.0 1.5 2 0 0 2 2 2 0 Prenylcysteine lyase RVT_1 PF00078.27 KRH91846.1 - 2.8e-09 36.8 0.1 3.9e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Prenylcys_lyase PF07156.14 KRH91846.1 - 0.0068 15.6 0.1 0.0076 15.4 0.1 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase DUF5305 PF17231.2 KRH91846.1 - 0.086 12.2 0.3 2.8 7.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) RVT_1 PF00078.27 KRH91848.1 - 1.7e-18 66.9 0.1 2e-18 66.7 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UL41A PF17591.2 KRH91848.1 - 0.035 14.2 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL41A Integrase_H2C2 PF17921.1 KRH91849.1 - 9.7e-09 35.2 0.7 1.5e-08 34.6 0.7 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 KRH91849.1 - 0.00037 20.3 0.9 0.00071 19.4 0.9 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KRH91849.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain MFS_1_like PF12832.7 KRH91850.1 - 3e-14 52.7 9.7 7e-14 51.5 9.7 1.5 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 KRH91850.1 - 0.0071 15.2 8.2 0.0099 14.7 8.2 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1 PF07690.16 KRH91850.1 - 0.025 13.5 8.7 0.012 14.6 6.4 1.5 1 1 0 2 2 2 0 Major Facilitator Superfamily rve PF00665.26 KRH91851.1 - 4.6e-12 46.2 0.1 8.4e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH91851.1 - 0.02 14.7 0.5 0.19 11.5 0.1 2.7 2 1 0 2 2 2 0 Integrase core domain RVP PF00077.20 KRH91852.1 - 8.9e-05 22.7 0.6 0.00026 21.3 0.1 1.8 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH91852.1 - 0.00018 22.0 0.1 0.00066 20.3 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH91852.1 - 0.00025 21.6 0.3 0.00087 19.8 0.1 1.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease RNase_P_Rpp14 PF01900.19 KRH91853.1 - 8.9e-12 45.2 0.1 1e-11 45.0 0.1 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family SNF2_N PF00176.23 KRH91854.1 - 8.5e-16 57.6 0.3 1.2e-15 57.2 0.3 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KRH91854.1 - 0.0028 17.7 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NinE PF05322.11 KRH91854.1 - 0.028 14.3 0.8 0.071 13.0 0.8 1.6 1 0 0 1 1 1 0 NINE Protein CDtoxinA PF03498.14 KRH91857.1 - 0.0021 17.6 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 KRH91857.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like HTH_Tnp_Tc3_2 PF01498.18 KRH91858.1 - 4.5e-11 42.8 0.3 4.5e-11 42.8 0.3 1.5 1 1 1 2 2 2 1 Transposase HTH_32 PF13565.6 KRH91858.1 - 0.0055 17.3 0.0 0.016 15.8 0.0 1.7 1 1 1 2 2 2 1 Homeodomain-like domain Arg_repressor PF01316.21 KRH91858.1 - 0.012 15.4 0.2 0.017 14.9 0.2 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_33 PF13592.6 KRH91858.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Nop PF01798.18 KRH91862.1 - 2e-22 79.8 0.1 2e-22 79.8 0.1 1.4 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin RVT_1 PF00078.27 KRH91863.1 - 1.9e-25 89.7 0.9 2.2e-25 89.5 0.9 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH91864.1 - 1.5e-20 73.6 0.1 2e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4261 PF14080.6 KRH91864.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) TRM PF02005.16 KRH91866.1 - 1.3e-27 97.0 0.1 1.9e-27 96.5 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_16 PF10294.9 KRH91866.1 - 0.00012 21.9 0.1 0.00028 20.7 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase UCH PF00443.29 KRH91867.1 - 1.9e-09 37.4 1.9 3.2e-09 36.7 1.9 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH91867.1 - 0.0026 17.4 0.6 0.0038 16.9 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3139 PF11337.8 KRH91867.1 - 8.5 7.1 8.8 18 6.1 8.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DDE_Tnp_IS1595 PF12762.7 KRH91868.1 - 2.2e-08 34.3 0.1 3e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF962 PF06127.11 KRH91869.1 - 0.0052 16.8 0.0 0.033 14.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF962) PAP_central PF04928.17 KRH91870.1 - 3.3e-70 235.9 0.1 3.6e-70 235.8 0.1 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain RVT_1 PF00078.27 KRH91872.1 - 7.9e-05 22.3 0.0 8.6e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BK_channel_a PF03493.18 KRH91873.1 - 0.096 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit UCH PF00443.29 KRH91874.1 - 1.7e-09 37.6 1.3 1.7e-09 37.6 1.3 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH91874.1 - 0.0072 16.0 1.4 0.016 14.8 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KRH91875.1 - 8.9e-08 32.7 0.0 0.016 16.1 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat RIBIOP_C PF04950.12 KRH91876.1 - 4.2e-11 42.8 0.2 4.2e-11 42.8 0.2 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal DDE_Tnp_IS1595 PF12762.7 KRH91877.1 - 1.5e-22 80.2 0.0 1.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Ribosomal_L3 PF00297.22 KRH91878.1 - 3.9e-23 82.0 0.0 4.4e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 FeS_assembly_P PF01883.19 KRH91879.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein DnaB_2 PF07261.11 KRH91879.1 - 0.041 13.6 0.2 2.3 8.0 0.1 2.6 2 1 0 2 2 2 0 Replication initiation and membrane attachment Bap31 PF05529.12 KRH91880.1 - 0.032 14.1 1.9 0.036 13.9 0.3 1.9 2 1 0 2 2 2 0 Bap31/Bap29 transmembrane region Protocadherin PF08374.11 KRH91880.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Protocadherin CcmH PF03918.14 KRH91880.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein ATP-synt_8 PF00895.20 KRH91880.1 - 0.34 11.4 3.2 0.56 10.7 0.5 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4446 PF14584.6 KRH91880.1 - 0.56 10.2 6.5 0.33 10.9 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Ly49 PF08391.10 KRH91880.1 - 2.3 8.6 5.6 1.1 9.7 0.2 2.2 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region rve PF00665.26 KRH91881.1 - 6.5e-05 23.1 0.0 8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain P21-Arc PF04062.14 KRH91881.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit Ribosomal_L3 PF00297.22 KRH91883.1 - 7.9e-58 196.2 0.8 8.7e-58 196.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF5091 PF17012.5 KRH91884.1 - 1.3e-39 135.8 6.9 1.8e-39 135.3 6.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5091) RT_RNaseH PF17917.1 KRH91886.1 - 1.1e-20 73.8 0.1 2.3e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH91886.1 - 4.5e-13 49.1 0.1 8.5e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH91886.1 - 3e-08 33.7 0.1 6.6e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 KRH91886.1 - 6.9e-07 29.0 0.1 1.5e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-H2C2 PF09337.10 KRH91886.1 - 0.048 13.9 1.5 0.29 11.4 0.3 2.6 2 1 0 2 2 2 0 H2C2 zinc finger RNase_H PF00075.24 KRH91886.1 - 0.13 12.4 0.4 0.31 11.2 0.3 1.9 1 1 1 2 2 2 0 RNase H DUF2203 PF09969.9 KRH91886.1 - 0.35 11.6 1.7 1.2 9.9 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) T2SSE PF00437.20 KRH91887.1 - 1.7e-06 27.3 0.1 1.9e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 KRH91887.1 - 7.2e-06 26.0 0.3 1.4e-05 25.1 0.2 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KRH91887.1 - 5.5e-05 23.5 0.0 9.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KRH91887.1 - 0.0011 18.5 0.2 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_10 PF12846.7 KRH91887.1 - 0.0021 17.1 0.1 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 KRH91887.1 - 0.0026 17.9 2.5 0.04 14.0 1.4 2.1 1 1 1 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KRH91887.1 - 0.0037 17.7 0.0 0.0038 17.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KRH91887.1 - 0.0056 16.4 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRH91887.1 - 0.017 15.2 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KRH91887.1 - 0.017 14.4 0.3 0.12 11.6 0.3 2.0 1 1 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KRH91887.1 - 0.03 13.7 0.5 0.048 13.0 0.4 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 KRH91887.1 - 0.031 13.5 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KRH91887.1 - 0.031 14.0 0.2 0.064 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KRH91887.1 - 0.032 13.9 0.1 0.064 13.0 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.15 KRH91887.1 - 0.051 13.6 3.2 0.27 11.2 3.2 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 KRH91887.1 - 0.057 13.2 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF853 PF05872.12 KRH91887.1 - 0.067 11.8 0.1 0.097 11.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) MMR_HSR1 PF01926.23 KRH91887.1 - 0.083 13.0 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 KRH91887.1 - 0.089 11.7 0.4 0.11 11.4 0.4 1.4 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 KRH91887.1 - 0.1 12.9 0.5 0.54 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KRH91887.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KRH91887.1 - 0.22 12.0 1.9 0.76 10.3 1.9 1.8 1 1 0 1 1 1 0 ABC transporter RVP PF00077.20 KRH91888.1 - 2.5e-08 34.1 0.0 4.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH91888.1 - 6.5e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH91888.1 - 0.00016 22.2 0.0 0.00054 20.6 0.0 1.9 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH91888.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH91888.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase TOM13 PF08219.11 KRH91889.1 - 0.097 12.6 2.4 0.16 11.9 0.3 1.8 1 1 1 2 2 2 0 Outer membrane protein TOM13 Anticodon_1 PF08264.13 KRH91891.1 - 0.0017 18.3 3.0 0.0044 17.0 2.9 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA DNA_gyraseB PF00204.25 KRH91892.1 - 7.8e-08 32.0 0.1 2.7e-07 30.2 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase B Galanin PF01296.18 KRH91892.1 - 0.81 9.7 9.3 31 4.7 0.1 4.0 3 1 1 4 4 4 0 Galanin zn-ribbon_14 PF16503.5 KRH91894.1 - 0.0078 15.7 6.1 0.018 14.5 6.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon DUF3767 PF12597.8 KRH91895.1 - 1.1 9.1 9.0 25 4.8 0.2 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3767) Maf PF02545.14 KRH91896.1 - 0.025 14.4 0.9 7.3 6.4 0.0 2.5 1 1 1 3 3 3 0 Maf-like protein MucB_RseB PF03888.14 KRH91898.1 - 0.0058 16.2 0.9 0.015 14.9 0.5 1.8 2 0 0 2 2 2 1 MucB/RseB N-terminal domain 5_3_exonuc PF01367.20 KRH91898.1 - 0.096 13.3 0.8 0.096 13.3 0.8 2.5 1 1 2 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold AAA_14 PF13173.6 KRH91898.1 - 0.2 11.7 6.4 0.5 10.4 6.1 1.9 1 1 0 1 1 1 0 AAA domain DUF745 PF05335.13 KRH91898.1 - 1.5 8.5 8.6 2.1 8.0 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec20 PF03908.13 KRH91898.1 - 9.4 6.2 12.7 0.89 9.5 2.0 2.8 2 1 1 3 3 3 0 Sec20 Pkinase PF00069.25 KRH91899.1 - 2.5e-21 76.2 0.2 2.5e-21 76.2 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH91899.1 - 1.1e-12 47.9 0.1 1.8e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KRH91899.1 - 0.00013 21.0 0.1 0.00013 21.0 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KRH91899.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KRH91899.1 - 0.03 14.2 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Atg14 PF10186.9 KRH91899.1 - 0.046 12.8 8.5 0.068 12.2 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRIF1 PF15741.5 KRH91899.1 - 0.36 9.3 6.6 6.2 5.2 0.0 2.0 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 FTA2 PF13095.6 KRH91899.1 - 0.51 9.9 3.4 1.4 8.5 3.4 1.9 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KRH91899.1 - 0.66 8.7 9.5 5 5.8 9.4 2.0 1 1 0 1 1 1 0 Fungal protein kinase Ribosomal_L44 PF00935.19 KRH91900.1 - 9.6e-25 86.9 15.6 1.7e-24 86.1 15.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Rpr2 PF04032.16 KRH91900.1 - 1.2 9.4 9.8 2 8.7 9.8 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ProRS-C_1 PF09180.11 KRH91901.1 - 5.7e-21 74.5 1.2 8e-21 74.0 1.2 1.2 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal SMI1_KNR4 PF09346.10 KRH91901.1 - 0.07 13.5 0.1 0.2 12.1 0.1 1.9 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 KRH91901.1 - 0.081 13.3 0.4 0.2 12.1 0.4 1.8 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall rve PF00665.26 KRH91902.1 - 0.004 17.3 0.0 0.004 17.3 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 KRH91903.1 - 4e-18 65.6 0.1 4.6e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH91903.1 - 3e-08 33.6 0.0 4.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KRH91903.1 - 0.0073 16.1 0.0 0.0079 16.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase-like HydF_tetramer PF18133.1 KRH91903.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain RT_RNaseH PF17917.1 KRH91904.1 - 2.6e-23 82.3 0.7 2.7e-23 82.2 0.7 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH91904.1 - 4.8e-13 49.0 0.2 7.3e-13 48.4 0.1 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase AcMNPV_Ac109 PF05054.12 KRH91905.1 - 0.11 11.5 2.6 0.11 11.5 2.6 1.0 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein Endonuc-PvuII PF09225.10 KRH91906.1 - 0.052 13.3 2.0 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 Restriction endonuclease PvuII MLVIN_C PF18697.1 KRH91906.1 - 0.077 13.1 0.4 0.15 12.2 0.0 1.7 2 1 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-RING_5 PF14634.6 KRH91907.1 - 1.9e-05 24.5 9.7 3.7e-05 23.6 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KRH91907.1 - 0.0012 18.6 4.8 0.0021 17.9 4.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KRH91907.1 - 0.0014 18.4 6.4 0.0027 17.6 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KRH91907.1 - 0.002 17.9 4.4 0.0062 16.4 4.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRH91907.1 - 0.0024 17.8 4.2 0.0061 16.6 4.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KRH91907.1 - 0.008 16.0 12.3 0.1 12.5 12.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KRH91907.1 - 0.037 14.2 7.5 0.11 12.6 2.9 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1465 PF07323.12 KRH91907.1 - 0.059 13.2 0.7 0.21 11.4 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) ZapB PF06005.12 KRH91907.1 - 0.071 13.6 9.1 0.15 12.5 9.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB NRBF2 PF08961.10 KRH91907.1 - 0.11 12.0 4.3 0.16 11.5 4.3 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_1 PF00170.21 KRH91907.1 - 0.58 10.3 8.5 0.75 9.9 6.8 2.1 1 1 1 2 2 2 0 bZIP transcription factor zf-RING_2 PF13639.6 KRH91907.1 - 1 9.7 11.9 0.17 12.2 7.5 1.9 2 0 0 2 2 2 0 Ring finger domain PikAIV_N PF18605.1 KRH91907.1 - 3.1 7.5 5.7 0.88 9.2 1.5 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5101 PF17031.5 KRH91908.1 - 4.4e-25 87.7 10.2 5.2e-25 87.4 10.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) Tai4 PF16695.5 KRH91908.1 - 0.039 14.5 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein DUF1319 PF07028.11 KRH91908.1 - 0.045 14.0 0.8 0.045 14.0 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) CH PF00307.31 KRH91910.1 - 3.3e-10 40.1 0.1 6e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KRH91910.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain TAF4 PF05236.14 KRH91911.1 - 0.017 14.9 4.3 0.061 13.1 2.7 2.2 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family TFIID-18kDa PF02269.16 KRH91911.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.2 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit zf-CCCH_7 PF18586.1 KRH91911.1 - 0.53 10.7 2.3 3.4 8.1 0.3 2.4 2 1 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 TFIIA_gamma_N PF02268.16 KRH91912.1 - 8.5e-15 54.5 0.2 1.1e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KRH91912.1 - 0.00019 21.5 2.2 0.00034 20.7 0.6 1.9 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit DUF836 PF05768.14 KRH91912.1 - 0.017 15.5 0.1 0.019 15.4 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PseudoU_synth_1 PF01416.20 KRH91913.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase Acetyltransf_11 PF13720.6 KRH91913.1 - 0.12 12.9 0.2 0.43 11.1 0.0 2.0 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CTD PF12815.7 KRH91914.1 - 0.013 16.0 10.9 0.013 16.0 10.9 2.1 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 RRM_1 PF00076.22 KRH91916.1 - 1.9e-29 101.3 4.3 6.9e-12 45.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KRH91916.1 - 3.3e-10 39.9 1.4 0.00019 21.5 0.2 4.1 3 1 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 KRH91916.1 - 1.6e-08 34.4 0.9 0.054 13.5 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KRH91916.1 - 1.9e-05 24.4 0.8 0.63 9.9 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_3 PF08777.11 KRH91916.1 - 0.00055 19.9 1.9 2.2 8.4 0.1 3.2 3 0 0 3 3 3 2 RNA binding motif PHM7_cyt PF14703.6 KRH91916.1 - 0.0031 17.8 1.5 6.3 7.0 0.1 3.3 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 KRH91916.1 - 0.035 13.9 5.2 4.1 7.2 2.0 3.1 1 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Zip PF02535.22 KRH91917.1 - 0.0088 15.3 0.2 0.0088 15.3 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CAF-1_p150 PF11600.8 KRH91917.1 - 0.019 14.7 11.0 0.026 14.2 11.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sel1 PF08238.12 KRH91917.1 - 5.5 7.8 8.4 0.31 11.8 1.9 2.3 3 0 0 3 3 3 0 Sel1 repeat TF_Zn_Ribbon PF08271.12 KRH91918.1 - 4.8e-13 48.4 0.8 7.4e-13 47.8 0.8 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 KRH91918.1 - 0.0017 18.0 0.7 0.003 17.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 DZR PF12773.7 KRH91918.1 - 0.016 15.3 0.3 0.03 14.3 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KRH91918.1 - 0.016 15.1 0.5 0.032 14.1 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KRH91918.1 - 0.017 14.5 2.0 0.34 10.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KRH91918.1 - 0.024 14.3 2.1 1 9.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 KRH91918.1 - 0.047 13.8 1.9 0.076 13.1 0.6 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) zf_UBZ PF18439.1 KRH91918.1 - 0.095 12.3 0.9 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ArfGap PF01412.18 KRH91918.1 - 0.25 11.4 4.6 0.082 13.0 0.8 1.9 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf SAP PF02037.27 KRH91920.1 - 6.4e-10 38.6 0.4 1.2e-09 37.6 0.4 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 KRH91920.1 - 0.00098 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Ish1 PF10281.9 KRH91920.1 - 0.0032 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KRH91920.1 - 0.0086 15.8 0.6 0.91 9.3 0.6 2.6 1 1 0 1 1 1 1 HeH/LEM domain LETM1 PF07766.13 KRH91920.1 - 0.035 13.5 0.4 0.061 12.7 0.2 1.5 1 1 0 1 1 1 0 LETM1-like protein EF-G-binding_N PF07299.11 KRH91920.1 - 0.035 14.6 0.2 0.049 14.2 0.2 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal WD40 PF00400.32 KRH91921.1 - 9.1e-08 32.7 2.9 0.28 12.1 0.0 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 KRH91921.1 - 7.3e-07 28.8 13.8 0.00039 19.9 4.7 2.0 1 1 1 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 KRH91921.1 - 0.0054 16.8 1.4 0.53 10.3 0.1 2.6 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 KRH91921.1 - 0.0098 16.2 0.1 1.2 9.5 0.0 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RHD3 PF05879.12 KRH91921.1 - 0.011 14.0 0.0 0.015 13.4 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) HEAT_2 PF13646.6 KRH91923.1 - 9.8e-08 32.3 0.0 0.014 15.7 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 KRH91923.1 - 0.0024 18.4 0.0 0.81 10.5 0.0 3.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat ERAP1_C PF11838.8 KRH91923.1 - 0.071 12.6 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Methyltransf_25 PF13649.6 KRH91924.1 - 4.4e-11 43.3 0.0 8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRH91924.1 - 7.1e-11 42.6 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH91924.1 - 1.4e-09 37.9 0.1 2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRH91924.1 - 3.4e-08 34.1 0.0 5.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KRH91924.1 - 6.7e-06 25.8 0.0 9.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 KRH91924.1 - 7.6e-05 22.6 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KRH91924.1 - 9.5e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_N4_Mtase PF01555.18 KRH91924.1 - 0.00045 20.0 1.8 0.0072 16.1 0.1 2.1 2 0 0 2 2 2 1 DNA methylase AviRa PF11599.8 KRH91924.1 - 0.00058 19.4 0.1 0.0012 18.3 0.2 1.4 2 0 0 2 2 2 1 RRNA methyltransferase AviRa CMAS PF02353.20 KRH91924.1 - 0.0071 15.7 0.2 0.013 14.8 0.2 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KRH91924.1 - 0.0076 16.2 0.2 0.018 15.0 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KRH91924.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 KRH91924.1 - 0.015 14.8 0.1 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 KRH91924.1 - 0.1 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1_like PF12832.7 KRH91925.1 - 2e-09 36.8 13.0 1.7e-08 33.7 13.0 1.9 1 1 0 1 1 1 1 MFS_1 like family RtcB PF01139.17 KRH91926.1 - 3.4e-25 89.1 8.8 1.9e-21 76.8 0.5 3.0 1 1 2 3 3 2 2 tRNA-splicing ligase RtcB RR_TM4-6 PF06459.12 KRH91926.1 - 0.051 13.4 22.6 0.071 12.9 22.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 KRH91926.1 - 0.14 11.4 25.1 0.19 10.9 25.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pertus-S5-tox PF09276.10 KRH91926.1 - 0.16 12.0 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Pertussis toxin S5 subunit Nop53 PF07767.11 KRH91926.1 - 0.16 11.3 28.5 0.2 11.0 28.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NARP1 PF12569.8 KRH91926.1 - 0.21 10.5 23.1 0.28 10.1 23.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.6 KRH91926.1 - 0.31 11.5 23.2 0.45 11.0 23.2 1.4 1 0 0 1 1 1 0 AAA domain HCO3_cotransp PF00955.21 KRH91926.1 - 0.68 8.7 5.5 0.74 8.6 5.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family SprA-related PF12118.8 KRH91926.1 - 0.74 8.9 22.2 0.96 8.5 22.2 1.1 1 0 0 1 1 1 0 SprA-related family AAA_11 PF13086.6 KRH91926.1 - 0.88 9.3 17.4 1.2 8.9 17.4 1.3 1 0 0 1 1 1 0 AAA domain SID-1_RNA_chan PF13965.6 KRH91926.1 - 1.2 7.4 10.9 1.5 7.2 10.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CSG2 PF16965.5 KRH91926.1 - 1.3 7.9 8.5 1.8 7.4 8.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator GREB1 PF15782.5 KRH91926.1 - 2.3 5.2 17.8 2.6 5.1 17.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 KRH91926.1 - 2.4 7.0 15.8 3 6.6 15.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GAGA_bind PF06217.12 KRH91926.1 - 2.5 8.3 19.5 3.1 8.0 19.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 KRH91926.1 - 5.2 5.7 18.1 6.9 5.3 18.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KRH91926.1 - 5.2 5.6 9.4 6.7 5.3 9.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOBP PF15279.6 KRH91926.1 - 7.4 7.1 13.3 9.5 6.7 13.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TF_Zn_Ribbon PF08271.12 KRH91928.1 - 5.2e-13 48.3 0.8 8e-13 47.7 0.8 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 KRH91928.1 - 0.0017 18.0 0.7 0.0032 17.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 DZR PF12773.7 KRH91928.1 - 0.017 15.1 0.3 0.032 14.2 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KRH91928.1 - 0.017 15.0 0.5 0.035 14.0 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KRH91928.1 - 0.02 14.3 2.0 0.36 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KRH91928.1 - 0.027 14.2 2.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.9 KRH91928.1 - 0.055 13.6 2.1 0.072 13.2 0.7 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) ArfGap PF01412.18 KRH91928.1 - 0.081 13.0 0.7 0.081 13.0 0.7 1.9 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf_UBZ PF18439.1 KRH91928.1 - 0.1 12.2 0.9 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RVT_1 PF00078.27 KRH91929.1 - 7.7e-25 87.7 0.3 9.7e-25 87.4 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KRH91929.1 - 0.013 15.2 0.2 2.7 7.6 0.2 2.4 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH91930.1 - 0.0006 19.6 0.8 0.00076 19.3 0.8 1.1 1 0 0 1 1 1 1 Reverse transcriptase thumb domain DDE_3 PF13358.6 KRH91933.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rRNA_methylase PF06962.12 KRH91933.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative rRNA methylase NFACT-R_1 PF05670.13 KRH91935.1 - 1.3e-06 29.0 0.0 4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain RAC_head PF16717.5 KRH91935.1 - 0.39 11.7 8.5 3.6 8.6 3.6 2.5 2 0 0 2 2 2 0 Ribosome-associated complex head domain ER_lumen_recept PF00810.18 KRH91936.1 - 1.6e-37 129.6 19.9 1.6e-37 129.6 19.9 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor gag-asp_proteas PF13975.6 KRH91938.1 - 0.15 12.6 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 KRH91940.1 - 1.1e-20 74.1 0.4 1.5e-20 73.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH91940.1 - 1.5e-05 24.9 1.1 4.1e-05 23.5 0.1 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase MOZ_SAS PF01853.18 KRH91941.1 - 7.4e-23 81.1 0.2 1.4e-22 80.2 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KRH91941.1 - 3.5e-16 58.5 1.4 6.6e-16 57.7 1.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KRH91941.1 - 4.3e-09 36.1 0.2 4.3e-09 36.1 0.2 1.7 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-C2HE PF16278.5 KRH91941.1 - 0.027 14.9 1.6 0.24 11.9 1.6 2.3 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PhoU_div PF01865.16 KRH91941.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 HATPase_c PF02518.26 KRH91943.1 - 1.4e-11 44.9 0.0 1.9e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase fn3_5 PF06280.12 KRH91944.1 - 0.86 10.3 10.9 14 6.4 10.9 2.2 1 1 0 1 1 1 0 Fn3-like domain Methyltr_RsmF_N PF17125.5 KRH91944.1 - 2 9.0 4.6 3.7 8.1 0.3 2.1 1 1 1 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF PY_rept_46 PF09689.10 KRH91944.1 - 3.5 8.3 17.0 7 7.3 3.7 2.2 1 1 1 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) GIY-YIG PF01541.24 KRH91944.1 - 5.4 7.4 11.4 8.8e+02 0.3 11.3 2.5 1 1 0 1 1 1 0 GIY-YIG catalytic domain Yippee-Mis18 PF03226.14 KRH91945.1 - 0.0034 17.6 3.0 0.026 14.7 3.0 2.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RestrictionMunI PF11407.8 KRH91945.1 - 0.025 14.3 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI Homeodomain PF00046.29 KRH91946.1 - 1.1e-14 54.0 1.6 2.2e-14 53.0 1.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH91946.1 - 1e-10 41.3 0.5 2.2e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Mpp10 PF04006.12 KRH91947.1 - 1.4e-10 40.3 9.4 1.4e-10 40.3 9.4 1.8 1 1 1 2 2 2 1 Mpp10 protein ubiquitin PF00240.23 KRH91947.1 - 0.053 13.3 2.9 0.15 11.8 0.9 2.5 2 0 0 2 2 2 0 Ubiquitin family YkyA PF10368.9 KRH91948.1 - 0.011 15.4 0.5 0.021 14.5 0.5 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DASH_Duo1 PF08651.10 KRH91948.1 - 0.14 11.9 2.4 0.36 10.6 2.4 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 tRNA-synt_1b PF00579.25 KRH91949.1 - 3.5e-12 46.3 0.0 4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) EF-hand_7 PF13499.6 KRH91950.1 - 2.6e-11 43.8 1.6 5.3e-09 36.4 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KRH91950.1 - 4.3e-11 41.8 1.2 0.00022 20.9 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 KRH91950.1 - 4.5e-11 41.5 10.4 1.1e-06 27.8 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KRH91950.1 - 4.4e-09 36.0 1.3 1.2e-06 28.2 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KRH91950.1 - 1.6e-07 30.5 0.8 0.00011 21.5 0.0 3.4 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 KRH91950.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_lysozyme PF00959.19 KRH91950.1 - 0.033 14.6 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage lysozyme Lipin_N PF04571.14 KRH91951.1 - 1.3e-09 37.9 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 lipin, N-terminal conserved region CDtoxinA PF03498.14 KRH91952.1 - 0.0047 16.5 0.8 0.013 15.1 0.5 1.5 1 1 0 1 1 1 1 Cytolethal distending toxin A/C domain CooC_C PF15976.5 KRH91952.1 - 0.091 12.8 0.0 2.8 8.0 0.0 2.2 1 1 1 2 2 2 0 CS1-pili formation C-terminal Ricin_B_lectin PF00652.22 KRH91952.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Zn-C2H2_12 PF18112.1 KRH91954.1 - 0.038 14.4 0.2 0.17 12.4 0.2 2.2 1 1 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_3rep PF18868.1 KRH91954.1 - 0.095 13.4 4.1 0.17 12.5 1.1 2.5 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF87 PF01935.17 KRH91954.1 - 0.11 12.5 1.9 0.16 12.1 1.9 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain zf-C2H2_4 PF13894.6 KRH91954.1 - 2.3 9.3 4.4 0.88 10.6 0.7 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger PBP1_TM PF14812.6 KRH91954.1 - 5.3 7.5 9.6 0.43 11.0 4.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_IS1595 PF12762.7 KRH91955.1 - 0.068 13.2 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain GalKase_gal_bdg PF10509.9 KRH91957.1 - 0.14 11.8 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Galactokinase galactose-binding signature RT_RNaseH_2 PF17919.1 KRH91959.1 - 1.5e-23 82.7 0.0 3.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH91959.1 - 1.1e-19 70.7 0.0 2.3e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 KRH91959.1 - 5.3e-05 23.0 0.0 0.0002 21.2 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase thumb domain F_bP_aldolase PF01116.20 KRH91959.1 - 0.0072 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RVT_3 PF13456.6 KRH91959.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like Microtub_bd PF16796.5 KRH91959.1 - 0.13 12.2 2.5 0.75 9.7 0.6 2.4 1 1 0 2 2 2 0 Microtubule binding Rhodanese PF00581.20 KRH91960.1 - 1.4e-15 57.7 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_L3 PF00297.22 KRH91961.1 - 1.2e-15 57.4 0.2 1.3e-15 57.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TLD PF07534.16 KRH91962.1 - 2e-31 109.0 2.9 2.5e-31 108.7 2.9 1.1 1 0 0 1 1 1 1 TLD Glyco_transf_20 PF00982.21 KRH91963.1 - 6.6e-24 84.4 1.0 3.6e-22 78.7 0.2 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KRH91963.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KRH91963.1 - 0.026 15.0 0.1 0.043 14.2 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 SPARC_Ca_bdg PF10591.9 KRH91963.1 - 2.1 8.7 8.1 0.23 11.8 1.7 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4878 PF12870.7 KRH91963.1 - 8.8 6.7 10.1 0.51 10.7 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4878) Glyco_transf_20 PF00982.21 KRH91964.1 - 2.7e-24 85.7 0.8 2.9e-22 79.0 0.4 2.5 1 1 1 2 2 2 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 KRH91964.1 - 0.027 14.0 0.1 0.078 12.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KRH91964.1 - 0.04 14.3 0.1 0.071 13.5 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 SPARC_Ca_bdg PF10591.9 KRH91964.1 - 0.95 9.8 7.4 0.25 11.7 1.8 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HIT PF01230.23 KRH91965.1 - 3.7e-17 62.8 2.1 6.4e-17 62.1 2.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KRH91965.1 - 2.4e-08 34.4 3.4 4.6e-08 33.5 3.4 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KRH91965.1 - 0.00016 21.5 3.5 0.00026 20.9 3.5 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 rve PF00665.26 KRH91966.1 - 1.1e-08 35.3 0.1 3.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KRH91966.1 - 0.00026 20.7 0.7 0.00052 19.7 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 KRH91966.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF4537 PF15057.6 KRH91966.1 - 0.0074 16.3 0.3 0.012 15.6 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) NERD PF08378.11 KRH91966.1 - 0.28 11.6 4.3 0.13 12.8 1.3 1.8 1 1 1 2 2 2 0 Nuclease-related domain HATPase_c_3 PF13589.6 KRH91967.1 - 3.2e-12 46.4 0.0 5.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KRH91967.1 - 4.4e-10 40.1 0.1 6.4e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.18 KRH91967.1 - 2.1e-07 30.2 2.6 3e-07 29.7 2.6 1.2 1 0 0 1 1 1 1 Hsp90 protein RNA_pol_A_bac PF01000.26 KRH91968.1 - 6.6e-17 61.9 0.2 1e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KRH91968.1 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Dynamitin PF04912.14 KRH91968.1 - 0.082 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Dynamitin Phage_G PF02306.15 KRH91968.1 - 0.098 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Major spike protein (G protein) DUF4391 PF14335.6 KRH91969.1 - 0.0059 16.4 0.3 0.0066 16.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) SMK-1 PF04802.15 KRH91969.1 - 0.071 12.9 0.1 0.073 12.9 0.1 1.0 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 RRS1 PF04939.12 KRH91970.1 - 1.6e-11 44.3 6.1 1.8e-11 44.2 6.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RT_RNaseH PF17917.1 KRH91971.1 - 1.3e-30 105.8 0.0 1.8e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH91971.1 - 4.9e-30 103.5 0.0 7.2e-30 103.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH91973.1 - 6.8e-05 23.0 0.0 8.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH91973.1 - 0.017 15.3 0.1 0.044 14.0 0.0 1.6 2 0 0 2 2 2 0 DDE domain tRNA-synt_2b PF00587.25 KRH91974.1 - 4.8e-09 36.4 0.0 5.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Codanin-1_C PF15296.6 KRH91974.1 - 0.052 13.6 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Codanin-1 C-terminus rve PF00665.26 KRH91975.1 - 3.9e-05 23.8 0.0 4.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DASH_Duo1 PF08651.10 KRH91975.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Sec8_exocyst PF04048.14 KRH91975.1 - 0.11 12.3 0.4 0.16 11.8 0.4 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain rve_3 PF13683.6 KRH91975.1 - 0.13 12.0 0.8 0.22 11.3 0.5 1.6 1 1 1 2 2 2 0 Integrase core domain DUF2318 PF10080.9 KRH91976.1 - 0.0022 18.1 0.1 0.0041 17.2 0.1 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2318) PKI PF02827.16 KRH91976.1 - 0.2 11.9 0.2 7.6 6.8 0.0 2.2 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor CCDC144C PF14915.6 KRH91977.1 - 0.041 13.0 3.9 0.063 12.4 3.9 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region RTT107_BRCT_6 PF16771.5 KRH91977.1 - 2 8.6 8.8 0.13 12.4 2.5 2.1 2 1 1 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain TFIIA_gamma_N PF02268.16 KRH91978.1 - 8.2e-15 54.6 0.2 1.1e-14 54.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KRH91978.1 - 0.001 19.2 1.5 0.0025 17.9 0.4 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit DUF836 PF05768.14 KRH91978.1 - 0.017 15.5 0.1 0.018 15.4 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Gti1_Pac2 PF09729.9 KRH91980.1 - 1.1e-35 123.3 3.0 1.2e-29 103.7 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DDE_Tnp_IS1595 PF12762.7 KRH91981.1 - 3.2e-18 66.2 0.3 4e-18 65.9 0.3 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF2179 PF10035.9 KRH91981.1 - 0.4 10.5 3.4 0.6 9.9 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) vATP-synt_E PF01991.18 KRH91982.1 - 8.7e-19 67.7 19.2 3.2e-18 65.9 19.2 1.7 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Exonuc_VII_L PF02601.15 KRH91982.1 - 0.26 10.8 5.4 0.31 10.6 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Intein_splicing PF14890.6 KRH91982.1 - 3.6 7.5 9.5 5.6 6.9 9.4 1.5 1 1 0 1 1 1 0 Intein splicing domain PLC-beta_C PF08703.10 KRH91982.1 - 5 7.1 23.4 63 3.5 23.5 2.0 1 1 0 1 1 1 0 PLC-beta C terminal ATP-synt_ab_N PF02874.23 KRH91983.1 - 0.07 13.7 0.3 0.08 13.5 0.3 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L13 PF00572.18 KRH91984.1 - 1.6e-05 25.1 0.8 0.0005 20.3 0.8 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Borrelia_REV PF03978.13 KRH91985.1 - 0.26 11.2 8.1 0.46 10.4 8.1 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Diphthami_syn_2 PF01902.17 KRH91986.1 - 3.8e-25 88.7 0.2 5.3e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Diphthamide synthase DUF2465 PF10239.9 KRH91986.1 - 0.0013 18.1 0.3 0.0022 17.3 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) Ribosomal_L22 PF00237.19 KRH91987.1 - 7.4e-20 71.1 0.7 1e-19 70.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ANT PF03374.14 KRH91987.1 - 0.015 15.6 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain zf-C2H2_jaz PF12171.8 KRH91988.1 - 0.012 15.9 2.5 0.012 15.9 2.5 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RicinB_lectin_2 PF14200.6 KRH91989.1 - 7.3e-05 23.4 0.0 0.00019 22.1 0.0 1.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KRH91989.1 - 0.053 13.1 0.0 0.088 12.4 0.0 1.4 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain TFIIIC_delta PF12657.7 KRH91989.1 - 0.084 12.8 0.0 0.099 12.6 0.0 1.0 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term SET PF00856.28 KRH91990.1 - 0.031 14.6 0.4 0.16 12.3 0.4 2.0 1 1 0 1 1 1 0 SET domain DUF3978 PF13123.6 KRH91990.1 - 0.1 12.3 0.5 0.65 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3978) RicinB_lectin_2 PF14200.6 KRH91991.1 - 4.5e-05 24.1 0.0 0.00013 22.6 0.0 1.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KRH91991.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain TFIIIC_delta PF12657.7 KRH91991.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term CHASE3 PF05227.13 KRH91992.1 - 0.0041 17.0 0.5 0.011 15.6 0.2 1.8 1 1 1 2 2 2 1 CHASE3 domain Erf4 PF10256.9 KRH91992.1 - 0.042 13.9 0.8 0.16 12.1 0.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Pentapeptide_4 PF13599.6 KRH91994.1 - 1.5e-07 31.5 1.2 0.0011 19.1 0.1 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) CKS PF01111.19 KRH91994.1 - 0.038 14.3 10.1 38 4.6 0.1 4.9 2 1 2 4 4 4 0 Cyclin-dependent kinase regulatory subunit HC2 PF07382.11 KRH91994.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 BCHF PF07284.11 KRH91994.1 - 0.24 11.4 16.1 1.7 8.7 6.3 2.1 1 1 1 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF5055 PF16478.5 KRH91994.1 - 5.9 7.2 14.1 15 5.8 5.1 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF5055) Gal-3-0_sulfotr PF06990.11 KRH91996.1 - 0.0041 16.0 0.7 0.0051 15.8 0.7 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Proteasome PF00227.26 KRH91997.1 - 5.5e-40 136.9 0.5 7.3e-40 136.5 0.5 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KRH91997.1 - 6.2e-10 38.6 1.4 7.7e-10 38.3 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature gag-asp_proteas PF13975.6 KRH91998.1 - 7.8e-10 39.2 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH91998.1 - 1.9e-07 31.6 0.0 3.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH91998.1 - 5.6e-06 26.2 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Ribosomal_L35Ae PF01247.18 KRH91999.1 - 2.2e-22 79.0 1.1 2.7e-10 40.2 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L35Ae RimM PF01782.18 KRH91999.1 - 1.9e-06 28.0 0.7 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 RimM N-terminal domain DDE_Tnp_IS1595 PF12762.7 KRH92000.1 - 1.5e-22 80.2 0.0 1.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain AAA_lid_3 PF17862.1 KRH92001.1 - 5.7e-07 29.2 0.0 6.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 AAA+ lid domain SMC_N PF02463.19 KRH92002.1 - 1e-19 70.8 0.2 4.6e-12 45.8 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRH92002.1 - 0.0016 18.4 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Prok-E2_B PF14461.6 KRH92002.1 - 0.013 15.2 0.6 0.024 14.3 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family B SbcCD_C PF13558.6 KRH92002.1 - 0.053 13.8 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APG6_N PF17675.1 KRH92002.1 - 0.074 13.6 5.2 0.13 12.8 5.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Pup PF05639.11 KRH92002.1 - 0.15 13.0 1.3 0.72 10.8 0.0 2.5 2 1 0 2 2 2 0 Pup-like protein Ribosomal_L6e PF01159.19 KRH92004.1 - 2e-05 25.1 0.3 0.00071 20.1 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L6e 2-oxogl_dehyd_N PF16078.5 KRH92006.1 - 0.075 12.6 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Metalloenzyme PF01676.18 KRH92007.1 - 4.3e-44 150.8 0.3 5e-44 150.5 0.3 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KRH92007.1 - 0.0035 17.0 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 KRH92007.1 - 0.0063 16.6 0.0 0.011 15.9 0.0 1.3 1 1 0 1 1 1 1 PglZ domain tRNA_synt_1c_R1 PF04558.15 KRH92007.1 - 0.1 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1b PF00579.25 KRH92008.1 - 0.002 17.5 0.0 0.0057 16.0 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) Pro_isomerase PF00160.21 KRH92009.1 - 8.8e-46 156.1 0.3 1e-45 155.8 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sugar_tr PF00083.24 KRH92010.1 - 1.3e-07 30.9 14.5 3.2e-07 29.6 14.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KRH92010.1 - 3.3e-07 29.5 3.7 3.3e-07 29.5 3.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KRH92010.1 - 0.0064 16.3 0.0 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DUF4396 PF14342.6 KRH92010.1 - 0.39 11.1 7.1 1.1 9.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) DUF4231 PF14015.6 KRH92010.1 - 3.1 8.3 6.7 3.5 8.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MgtE PF01769.16 KRH92010.1 - 3.3 8.1 10.8 0.16 12.3 3.8 2.0 1 1 1 2 2 2 0 Divalent cation transporter S4 PF01479.25 KRH92014.1 - 1.6e-08 34.2 0.1 2.8e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KRH92014.1 - 0.003 18.4 0.7 0.003 18.4 0.7 2.2 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain DUF1635 PF07795.11 KRH92014.1 - 0.13 12.2 1.1 0.18 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RT_RNaseH PF17917.1 KRH92015.1 - 7e-11 42.3 0.2 1.1e-10 41.8 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92015.1 - 2.5e-06 27.5 0.6 4.2e-06 26.7 0.6 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4896 PF16237.5 KRH92015.1 - 0.047 13.5 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Mei5_like PF17021.5 KRH92016.1 - 2.4e-25 88.9 12.7 2.6e-25 88.7 12.7 1.0 1 0 0 1 1 1 1 Putative double-strand recombination repair-like DUF4795 PF16043.5 KRH92016.1 - 0.011 15.4 0.6 0.014 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) HECT_2 PF09814.9 KRH92017.1 - 0.00013 21.0 1.2 0.00018 20.5 1.2 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RVT_1 PF00078.27 KRH92019.1 - 1.3e-17 64.1 0.0 1.4e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UL41A PF17591.2 KRH92019.1 - 0.026 14.6 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL41A RNA_pol_Rpb2_6 PF00562.28 KRH92020.1 - 1.5e-39 136.2 3.7 7.7e-39 133.9 3.7 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 DUF1387 PF07139.11 KRH92020.1 - 0.096 12.4 10.2 0.13 11.9 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ALMT PF11744.8 KRH92020.1 - 9.5 4.9 6.6 12 4.6 6.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Histone PF00125.24 KRH92022.1 - 6.7e-19 68.6 1.8 9.1e-19 68.1 1.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRH92022.1 - 0.0057 16.9 0.0 0.0098 16.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KRH92022.1 - 0.029 14.5 1.4 0.038 14.1 0.2 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold SIR2 PF02146.17 KRH92023.1 - 2.1e-20 73.4 0.1 3.3e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Sir2 family ADD_ATRX PF17981.1 KRH92023.1 - 0.49 10.3 4.5 3.6 7.5 0.1 2.8 2 1 1 3 3 3 0 Cysteine Rich ADD domain s48_45 PF07422.13 KRH92023.1 - 3.2 8.4 9.3 2.8 8.6 1.9 2.3 1 1 1 2 2 2 0 Sexual stage antigen s48/45 domain DDE_Tnp_IS1595 PF12762.7 KRH92024.1 - 2.3e-05 24.4 0.0 2.5e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain ABC_tran PF00005.27 KRH92025.1 - 1.8e-05 25.3 0.9 4.6e-05 24.0 0.1 1.8 1 1 1 2 2 2 1 ABC transporter AAA_16 PF13191.6 KRH92025.1 - 2.8e-05 24.5 0.0 4.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KRH92025.1 - 3.7e-05 23.7 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KRH92025.1 - 4.3e-05 24.1 1.4 5.4e-05 23.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KRH92025.1 - 0.00011 21.3 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KRH92025.1 - 0.00015 22.1 0.1 0.00032 21.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KRH92025.1 - 0.0002 21.0 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KRH92025.1 - 0.0023 18.0 0.2 0.0046 17.0 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 KRH92025.1 - 0.006 16.5 0.1 0.014 15.3 0.0 1.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KRH92025.1 - 0.0061 16.3 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KRH92025.1 - 0.0097 15.7 0.1 0.046 13.5 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arm-DNA-bind_2 PF12167.8 KRH92025.1 - 0.013 15.4 0.2 0.019 14.9 0.2 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain AAA_24 PF13479.6 KRH92025.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KRH92025.1 - 0.015 14.8 0.3 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 KRH92025.1 - 0.015 14.9 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KRH92025.1 - 0.018 15.4 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KRH92025.1 - 0.019 15.3 0.1 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 KRH92025.1 - 0.02 14.3 0.2 0.031 13.7 0.2 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KRH92025.1 - 0.024 13.8 0.8 0.084 12.1 0.1 1.9 1 1 1 2 2 2 0 NB-ARC domain MobB PF03205.14 KRH92025.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 KRH92025.1 - 0.03 14.2 0.1 0.086 12.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 KRH92025.1 - 0.035 13.9 0.3 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 KRH92025.1 - 0.05 13.8 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KRH92025.1 - 0.053 13.4 0.1 0.098 12.6 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KRH92025.1 - 0.059 13.6 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KRH92025.1 - 0.06 12.7 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 KRH92025.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KRH92025.1 - 0.063 13.0 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KRH92025.1 - 0.066 13.2 0.1 0.089 12.8 0.1 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KRH92025.1 - 0.07 12.4 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_11 PF13086.6 KRH92025.1 - 0.077 12.8 0.4 0.11 12.3 0.0 1.4 2 0 0 2 2 1 0 AAA domain PRK PF00485.18 KRH92025.1 - 0.079 12.7 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Kinesin PF00225.23 KRH92025.1 - 0.091 11.7 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain Dynamin_N PF00350.23 KRH92025.1 - 0.095 12.7 0.1 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KRH92025.1 - 0.13 12.8 0.1 0.3 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KRH92025.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KRH92025.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KRH92025.1 - 0.17 11.3 0.1 0.48 9.8 0.1 1.6 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DDE_3 PF13358.6 KRH92026.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 KRH92026.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Knl1_RWD_C PF18210.1 KRH92026.1 - 0.25 11.8 1.3 0.56 10.7 0.3 2.1 1 1 0 2 2 2 0 Knl1 RWD C-terminal domain Ricin_B_lectin PF00652.22 KRH92029.1 - 0.0063 16.8 0.1 0.0098 16.1 0.1 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KRH92029.1 - 0.0074 17.0 0.0 0.11 13.2 0.0 2.2 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like TTR-52 PF01060.23 KRH92029.1 - 0.02 15.6 1.0 0.028 15.1 0.1 1.8 2 0 0 2 2 2 0 Transthyretin-like family Inhibitor_I66 PF16850.5 KRH92029.1 - 0.059 13.2 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I66 rve PF00665.26 KRH92031.1 - 2.2e-06 27.8 0.0 3.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92031.1 - 0.0006 19.9 0.9 0.001 19.1 0.9 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 KRH92031.1 - 0.003 17.8 0.0 0.0042 17.3 0.0 1.2 1 0 0 1 1 1 1 DDE domain tRNA-synt_His PF13393.6 KRH92032.1 - 5.6e-20 71.8 0.0 1e-19 71.0 0.0 1.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KRH92032.1 - 1.4e-06 28.3 0.8 2.6e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KRH92032.1 - 0.03 13.8 0.1 0.03 13.8 0.1 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs HTH_ParB PF17762.1 KRH92032.1 - 0.05 13.4 1.2 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 HTH domain found in ParB protein Telomere_Sde2_2 PF13297.6 KRH92032.1 - 0.11 12.1 0.1 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Telomere stability C-terminal Ras PF00071.22 KRH92033.1 - 4.3e-48 163.0 0.4 5.4e-48 162.7 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH92033.1 - 1.5e-34 118.7 0.1 2.3e-34 118.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH92033.1 - 4e-15 55.7 0.1 4.6e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KRH92033.1 - 3.7e-08 33.1 0.0 2.3e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KRH92033.1 - 7.7e-08 32.0 0.1 1.1e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRH92033.1 - 8.9e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KRH92033.1 - 0.00012 21.5 0.1 0.00017 21.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KRH92033.1 - 0.0016 17.6 3.4 0.23 10.6 1.6 2.6 1 1 1 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 KRH92033.1 - 0.0094 15.7 0.3 0.017 14.8 0.3 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KRH92033.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 KRH92033.1 - 0.035 14.0 0.1 8.5 6.2 0.0 2.7 1 1 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KRH92033.1 - 0.067 12.9 0.1 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KRH92033.1 - 0.095 13.0 0.0 0.27 11.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain rve_3 PF13683.6 KRH92035.1 - 1.4e-06 28.0 0.1 3.5e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 KRH92035.1 - 5.3e-05 23.4 0.0 7.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Synaptobrevin PF00957.21 KRH92037.1 - 1e-07 31.7 2.4 1.4e-07 31.2 0.2 2.2 2 0 0 2 2 2 1 Synaptobrevin Erf4 PF10256.9 KRH92037.1 - 0.19 11.8 3.8 0.46 10.6 3.8 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family THOC7 PF05615.13 KRH92038.1 - 0.19 12.0 1.4 3.2 8.0 0.2 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 Abhydrolase_2 PF02230.16 KRH92040.1 - 1.7e-14 54.2 0.0 1.8e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KRH92040.1 - 0.00038 20.2 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KRH92040.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2974 PF11187.8 KRH92040.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.20 KRH92040.1 - 0.0045 16.7 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KRH92040.1 - 0.042 13.7 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KRH92040.1 - 0.047 12.2 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 KRH92040.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KRH92040.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ArgoN PF16486.5 KRH92041.1 - 0.0036 17.9 2.1 0.0053 17.4 1.6 1.6 1 1 0 1 1 1 1 N-terminal domain of argonaute NAGLU_N PF12971.7 KRH92041.1 - 0.17 11.7 1.9 13 5.7 0.1 2.4 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain LOR PF04525.12 KRH92042.1 - 0.025 14.2 0.7 0.045 13.4 0.5 1.5 1 1 1 2 2 2 0 LURP-one-related PepSY_like PF11396.8 KRH92042.1 - 0.04 14.5 2.8 0.42 11.2 0.1 2.3 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like dCMP_cyt_deam_1 PF00383.23 KRH92043.1 - 1.7e-06 27.9 0.3 2.5e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KRH92043.1 - 7.2e-05 22.6 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KRH92043.1 - 0.00081 19.5 0.7 0.0019 18.3 0.5 1.8 1 1 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 KRH92043.1 - 0.0061 16.6 0.6 0.012 15.7 0.6 1.5 1 0 0 1 1 1 1 APOBEC2 Str_synth PF03088.16 KRH92044.1 - 0.055 13.6 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Strictosidine synthase baeRF_family8 PF18851.1 KRH92044.1 - 0.061 13.4 0.0 7.7 6.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 RRM_1 PF00076.22 KRH92045.1 - 9.4e-09 35.0 0.1 0.0011 18.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AFOR_C PF01314.18 KRH92045.1 - 0.043 12.8 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 rve PF00665.26 KRH92046.1 - 1.1e-08 35.3 0.0 1.2e-08 35.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 KRH92047.1 - 6.3e-30 103.2 0.0 1.6e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92047.1 - 1.3e-25 89.7 0.0 2.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92047.1 - 3.7e-18 65.9 0.1 6.3e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V_ATPase_I PF01496.19 KRH92048.1 - 3.1e-11 42.0 7.9 1.6e-07 29.7 1.5 2.3 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DED PF01335.21 KRH92048.1 - 0.066 13.5 10.4 0.38 11.1 4.3 3.3 2 2 0 2 2 2 0 Death effector domain Pro_3_hydrox_C PF05373.11 KRH92048.1 - 0.44 10.6 3.0 5 7.3 0.2 3.0 3 1 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal ERCC4 PF02732.15 KRH92050.1 - 1.4e-17 64.3 0.6 2.5e-17 63.5 0.6 1.4 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.6 KRH92050.1 - 0.00014 21.7 0.9 0.00039 20.3 0.9 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix Tubulin PF00091.25 KRH92050.1 - 0.0095 16.1 0.4 0.014 15.6 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Branch PF02485.21 KRH92050.1 - 0.01 15.4 0.5 0.019 14.5 0.1 1.6 2 0 0 2 2 2 0 Core-2/I-Branching enzyme MarR PF01047.22 KRH92050.1 - 0.013 15.4 0.1 0.07 13.1 0.1 2.2 2 1 0 2 2 2 0 MarR family DUF4416 PF14385.6 KRH92050.1 - 0.043 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Topoisom_bac PF01131.20 KRH92050.1 - 0.052 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA topoisomerase ubiquitin PF00240.23 KRH92051.1 - 4.3e-09 36.0 0.8 9.3e-09 34.9 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.8 KRH92051.1 - 0.00066 20.1 1.1 0.0015 19.0 1.1 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 GerD PF17898.1 KRH92051.1 - 0.0081 16.1 5.4 0.021 14.7 5.4 1.7 1 0 0 1 1 1 1 Spore germination GerD central core domain RPN13_C PF16550.5 KRH92051.1 - 0.011 15.9 0.3 0.034 14.3 0.3 1.8 1 1 0 1 1 1 0 UCH-binding domain STI1 PF17830.1 KRH92051.1 - 0.28 11.2 8.6 0.49 10.4 2.6 2.5 2 0 0 2 2 2 0 STI1 domain Diphthamide_syn PF01866.17 KRH92052.1 - 2.5e-08 33.8 0.1 3.6e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Putative diphthamide synthesis protein PV-1 PF06637.11 KRH92052.1 - 0.2 10.4 4.2 0.24 10.2 4.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PET117 PF15786.5 KRH92052.1 - 5.3 7.4 14.0 16 5.8 14.0 1.8 1 1 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial CTP_transf_like PF01467.26 KRH92054.1 - 1.1e-16 61.3 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KRH92054.1 - 0.001 19.0 0.1 0.0074 16.2 0.0 2.2 1 1 1 2 2 2 1 FAD synthetase DUF2974 PF11187.8 KRH92054.1 - 0.059 12.9 0.2 0.08 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pantoate_ligase PF02569.15 KRH92054.1 - 0.063 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase GATase_7 PF13537.6 KRH92055.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain NTP_transferase PF00483.23 KRH92056.1 - 1.1e-46 159.5 0.0 1.2e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KRH92056.1 - 6.7e-07 29.8 0.0 8.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_like PF01467.26 KRH92057.1 - 8.1e-17 61.7 0.0 9.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KRH92057.1 - 0.0011 18.9 0.1 0.0071 16.3 0.0 2.2 1 1 1 2 2 2 1 FAD synthetase Pantoate_ligase PF02569.15 KRH92057.1 - 0.063 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Topoisom_bac PF01131.20 KRH92059.1 - 6e-21 74.9 0.1 1e-14 54.4 0.0 2.9 2 1 0 2 2 2 2 DNA topoisomerase Ribosomal_S19e PF01090.19 KRH92060.1 - 1.3e-26 92.9 0.0 8.1e-26 90.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 KRH92060.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Mrr N-terminal domain Lipase3_N PF03893.16 KRH92060.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase 3 N-terminal region UCH PF00443.29 KRH92062.1 - 1.2e-09 38.0 0.2 1.4e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH92062.1 - 0.012 15.2 0.2 0.013 15.1 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8 PF00410.19 KRH92063.1 - 2.4e-12 46.9 0.1 3.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DCAF15_WD40 PF14939.6 KRH92064.1 - 0.023 14.4 4.7 0.028 14.1 4.7 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Mei5 PF10376.9 KRH92065.1 - 0.011 15.6 0.3 0.017 15.0 0.3 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF2833 PF11090.8 KRH92065.1 - 0.082 13.3 0.2 0.18 12.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2833) DNA_gyraseB PF00204.25 KRH92066.1 - 8.4e-15 54.7 1.0 1.7e-14 53.7 1.0 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 KRH92066.1 - 3.6e-07 30.3 0.2 9.7e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Toprim domain BIRC6 PF12356.8 KRH92066.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 WD40 PF00400.32 KRH92067.1 - 4.1e-08 33.8 0.5 0.0035 18.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH92067.1 - 7.3e-05 23.0 0.0 0.43 10.9 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain GCS PF03074.16 KRH92068.1 - 1.5e-07 31.1 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Glutamate-cysteine ligase TPR_1 PF00515.28 KRH92069.1 - 3.5e-27 93.1 17.5 2.2e-07 30.4 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KRH92069.1 - 3.4e-25 86.1 7.4 7.6e-05 22.5 0.0 6.3 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KRH92069.1 - 1.7e-23 80.8 12.1 0.0029 17.7 0.0 6.5 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KRH92069.1 - 5.9e-18 64.9 0.3 0.0093 16.2 0.0 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KRH92069.1 - 1.2e-14 53.1 0.2 0.017 15.1 0.0 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KRH92069.1 - 1.1e-09 38.8 0.0 0.014 16.0 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KRH92069.1 - 7.5e-09 35.7 0.8 1.5 9.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KRH92069.1 - 1.2e-08 34.7 0.6 0.0021 18.3 0.0 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KRH92069.1 - 2.5e-08 34.1 0.0 1.1 10.2 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KRH92069.1 - 1.4e-06 27.9 4.3 0.12 12.1 0.0 4.8 4 1 1 5 5 5 2 TPR repeat TPR_19 PF14559.6 KRH92069.1 - 2.6e-06 27.9 0.0 0.12 12.9 0.0 3.8 1 1 3 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KRH92069.1 - 8.8e-05 22.7 9.4 0.031 14.5 0.4 3.9 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KRH92069.1 - 0.0013 18.8 0.0 2.6 8.2 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KRH92069.1 - 0.0014 18.4 0.0 8.7 6.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat HEPN_Apea PF18739.1 KRH92069.1 - 0.007 16.8 0.9 0.007 16.8 0.9 2.8 2 1 0 2 2 2 1 Apea-like HEPN tRNA-synt_2 PF00152.20 KRH92071.1 - 2.4e-54 184.6 0.0 2.7e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KRH92071.1 - 3e-05 23.6 0.2 0.0033 16.9 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Syja_N PF02383.18 KRH92072.1 - 5.4e-05 22.7 2.6 0.0012 18.2 2.6 2.2 1 1 0 1 1 1 1 SacI homology domain Integrase_H2C2 PF17921.1 KRH92075.1 - 1.2e-05 25.3 3.1 1.7e-05 24.9 3.1 1.2 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92075.1 - 0.0022 18.2 1.1 0.018 15.3 0.4 2.1 2 0 0 2 2 2 1 H2C2 zinc finger ELO PF01151.18 KRH92076.1 - 3.2e-46 157.9 27.7 4e-46 157.6 27.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Helicase_C PF00271.31 KRH92077.1 - 5e-08 33.3 0.9 2.9e-07 30.8 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Pkinase PF00069.25 KRH92078.1 - 1.2e-51 175.6 0.2 1.4e-51 175.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92078.1 - 2.5e-27 95.8 0.0 3.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH92078.1 - 5.7e-09 35.7 0.0 8.8e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KRH92078.1 - 2.3e-06 26.8 0.1 3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KRH92078.1 - 1.7e-05 24.3 0.1 3.7e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KRH92078.1 - 0.00051 19.7 0.2 0.00073 19.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KRH92078.1 - 0.0031 17.5 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KRH92078.1 - 0.0038 16.0 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DDE_Tnp_1_7 PF13843.6 KRH92081.1 - 3.5e-43 148.3 9.3 3.9e-43 148.1 9.3 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_3 PF13358.6 KRH92082.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Haspin_kinase PF12330.8 KRH92083.1 - 3.8e-16 59.0 13.3 1.5e-14 53.8 13.3 2.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KRH92083.1 - 0.00028 19.8 4.2 0.00036 19.4 4.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase SCAPER_N PF16501.5 KRH92083.1 - 0.4 10.7 3.8 1.5 8.9 0.1 3.1 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum DDE_3 PF13358.6 KRH92084.1 - 4.7e-15 55.6 0.2 7.1e-15 55.0 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Gti1_Pac2 PF09729.9 KRH92085.1 - 4.7e-40 137.6 6.9 8.9e-40 136.7 6.9 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family CAC1F_C PF16885.5 KRH92085.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Homeodomain PF00046.29 KRH92086.1 - 5.1e-21 74.3 8.5 7.5e-21 73.7 4.2 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KRH92086.1 - 0.037 13.9 0.2 0.066 13.1 0.2 1.6 1 1 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 KRH92086.1 - 0.088 12.3 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Tcp10_C PF07202.13 KRH92087.1 - 6e-05 23.1 1.3 8.3e-05 22.6 1.3 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus ETX_MTX2 PF03318.13 KRH92087.1 - 0.011 15.5 0.3 0.013 15.3 0.3 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 TRAF_BIRC3_bd PF16673.5 KRH92087.1 - 0.036 13.9 0.5 0.058 13.2 0.5 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain SPK PF04435.18 KRH92087.1 - 0.2 12.1 3.9 3.7 8.0 3.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF545) PLDc_2 PF13091.6 KRH92088.1 - 2.6e-06 27.4 0.4 5.4e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 PLD-like domain ABC2_membrane PF01061.24 KRH92089.1 - 0.00033 20.1 7.5 0.00042 19.8 7.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter OSTMP1 PF09777.9 KRH92089.1 - 0.02 14.3 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TMCCDC2 PF15844.5 KRH92089.1 - 0.49 10.3 3.4 0.5 10.3 0.3 2.1 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 zf-C2H2_4 PF13894.6 KRH92090.1 - 0.00011 22.7 10.6 0.054 14.4 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KRH92090.1 - 0.0019 18.6 0.2 0.0019 18.6 0.2 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KRH92090.1 - 0.1 13.2 0.9 0.1 13.2 0.9 3.7 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KRH92090.1 - 0.13 12.3 14.9 0.26 11.4 3.8 3.2 1 1 2 3 3 3 0 Aberrant zinc-finger PBECR3 PF18812.1 KRH92090.1 - 0.32 11.0 8.6 0.11 12.5 1.4 2.7 2 1 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 zf_Hakai PF18408.1 KRH92090.1 - 0.7 9.7 0.0 0.7 9.7 0.0 2.3 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-Di19 PF05605.12 KRH92090.1 - 1 9.7 6.3 3.5 8.0 1.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RVT PF13966.6 KRH92091.1 - 0.0038 17.9 0.0 0.0055 17.4 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.25 KRH92092.1 - 1.2e-42 146.1 3.3 1.4e-42 145.9 3.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92092.1 - 6.2e-24 84.7 0.2 7.6e-24 84.4 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KRH92092.1 - 0.00023 21.2 0.0 0.11 12.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KRH92092.1 - 0.00044 19.7 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Tetraspanin PF00335.20 KRH92093.1 - 1.3e-11 44.7 11.0 1.9e-11 44.2 11.0 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4577 PF15145.6 KRH92093.1 - 1.2 9.2 0.0 1.2 9.2 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4577) BatA PF07584.11 KRH92093.1 - 5.6 7.4 8.4 15 6.0 1.6 3.1 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Ribosomal_S24e PF01282.19 KRH92094.1 - 6.8e-12 45.2 3.7 9.4e-12 44.7 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Fiji_64_capsid PF05880.11 KRH92094.1 - 0.0085 14.7 0.9 0.02 13.5 0.5 1.7 1 1 1 2 2 2 1 Fijivirus 64 kDa capsid protein EMP24_GP25L PF01105.24 KRH92095.1 - 7.8e-07 29.2 1.8 1.1e-06 28.7 1.8 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Proteasome PF00227.26 KRH92096.1 - 3e-21 75.8 0.0 1.1e-19 70.6 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Arg_repressor PF01316.21 KRH92097.1 - 1.3e-07 31.3 3.8 2.2e-07 30.5 3.8 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DDE_3 PF13358.6 KRH92097.1 - 2.8e-07 30.4 0.1 6.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH92097.1 - 1e-05 25.6 2.5 2.1e-05 24.7 2.5 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.11 KRH92097.1 - 0.015 14.3 0.1 0.025 13.5 0.1 1.4 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_21 PF13276.6 KRH92097.1 - 0.082 13.1 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 HTH-like domain HTH_32 PF13565.6 KRH92097.1 - 0.1 13.3 0.2 0.46 11.1 0.1 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF3800 PF12686.7 KRH92097.1 - 0.26 11.9 3.5 17 6.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) SMC_N PF02463.19 KRH92098.1 - 4.2e-32 111.4 0.9 5.2e-32 111.1 0.9 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRH92098.1 - 1.4e-05 25.0 2.9 3.9e-05 23.6 2.9 1.8 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF3573 PF12097.8 KRH92098.1 - 0.0014 17.6 6.0 0.0025 16.7 6.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) RST PF12174.8 KRH92098.1 - 0.038 13.9 1.0 0.038 13.9 1.0 2.5 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain UQ_con PF00179.26 KRH92099.1 - 8.4e-10 38.4 0.6 1.2e-09 37.9 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRH92099.1 - 0.029 14.1 0.8 0.15 11.7 0.1 2.3 2 1 1 3 3 3 0 Prokaryotic E2 family B rve PF00665.26 KRH92101.1 - 3.6e-08 33.6 0.1 1.5e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KRH92101.1 - 0.00026 20.7 0.2 0.00072 19.3 0.2 1.9 1 1 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KRH92101.1 - 0.00074 19.6 0.0 0.0023 18.0 0.0 1.9 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain UCH_1 PF13423.6 KRH92101.1 - 0.0044 16.7 0.8 0.0049 16.5 0.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3947 PF13135.6 KRH92101.1 - 7.7 6.8 6.2 21 5.4 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3947) DUF3794 PF12673.7 KRH92102.1 - 0.013 15.7 1.9 5.9 7.2 1.9 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3794) ATP_bind_1 PF03029.17 KRH92103.1 - 2e-28 99.8 0.1 2.5e-17 63.5 0.1 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KRH92103.1 - 4.6e-06 27.2 0.0 6.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRH92103.1 - 3.4e-05 23.9 0.0 5.1e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KRH92103.1 - 0.00025 20.8 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KRH92103.1 - 0.00071 19.0 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 KRH92103.1 - 0.0009 19.5 0.0 0.0027 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH92103.1 - 0.0012 19.2 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KRH92103.1 - 0.0017 18.7 0.1 0.0036 17.7 0.0 1.6 2 0 0 2 2 1 1 RNA helicase PduV-EutP PF10662.9 KRH92103.1 - 0.0022 17.7 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KRH92103.1 - 0.003 18.1 0.0 0.0054 17.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 KRH92103.1 - 0.0034 17.8 0.0 0.0048 17.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KRH92103.1 - 0.0037 17.0 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CLP1_P PF16575.5 KRH92103.1 - 0.0054 16.5 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Rad17 PF03215.15 KRH92103.1 - 0.0054 16.7 0.1 0.0079 16.1 0.1 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain PRK PF00485.18 KRH92103.1 - 0.0077 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 KRH92103.1 - 0.0081 15.6 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein MMR_HSR1 PF01926.23 KRH92103.1 - 0.009 16.1 0.1 0.12 12.5 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KRH92103.1 - 0.019 14.9 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KRH92103.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KRH92103.1 - 0.032 14.2 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KRH92103.1 - 0.049 13.8 0.0 0.062 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4498 PF14926.6 KRH92103.1 - 0.058 12.7 0.0 0.093 12.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4498) AAA_7 PF12775.7 KRH92103.1 - 0.059 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KRH92103.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KRH92103.1 - 0.092 12.7 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 NTPase FYRN PF05964.14 KRH92104.1 - 8.8e-10 38.3 0.5 1.7e-09 37.4 0.5 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FTA4 PF13093.6 KRH92104.1 - 0.0092 15.9 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spa1_C PF18218.1 KRH92104.1 - 0.022 15.2 0.1 0.79 10.2 0.0 2.4 2 1 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain DUF2340 PF10209.9 KRH92104.1 - 0.026 15.0 1.8 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Repressor_Mnt PF11423.8 KRH92104.1 - 0.056 13.2 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Regulatory protein Mnt ArgoN PF16486.5 KRH92105.1 - 5.8e-10 39.9 0.6 1.1e-09 39.1 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KRH92105.1 - 9.3e-10 38.0 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Argonaute linker 1 domain Ribosomal_60s PF00428.19 KRH92105.1 - 0.028 15.0 0.8 0.046 14.3 0.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PIN_6 PF17146.4 KRH92106.1 - 2.2e-13 50.5 0.2 3.9e-13 49.7 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KRH92106.1 - 7.8e-08 32.4 1.7 1.6e-07 31.4 1.7 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like CLP1_P PF16575.5 KRH92107.1 - 3.7e-09 36.6 0.4 1.6e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KRH92107.1 - 0.0028 18.0 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MeaB PF03308.16 KRH92107.1 - 0.066 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SpoIIAA-like PF11964.8 KRH92107.1 - 0.19 12.8 0.3 1.1 10.3 0.0 2.1 2 0 0 2 2 2 0 SpoIIAA-like eIF-5_eIF-2B PF01873.17 KRH92108.1 - 5.9e-28 97.1 2.9 8.6e-28 96.6 2.9 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_10 PF10058.9 KRH92108.1 - 0.04 13.6 2.3 0.11 12.2 2.3 1.8 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein CT_C_D PF02682.16 KRH92108.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D TF_Zn_Ribbon PF08271.12 KRH92108.1 - 0.12 11.9 0.6 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RanBP PF00641.18 KRH92108.1 - 0.45 9.9 2.6 0.73 9.2 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others V_ATPase_I PF01496.19 KRH92109.1 - 6.1e-80 269.2 27.9 1.3e-79 268.2 27.9 1.4 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.19 KRH92110.1 - 1.4e-45 155.6 0.5 1.5e-45 155.5 0.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RSN1_TM PF13967.6 KRH92111.1 - 1.2e-18 67.4 13.0 1.7e-18 66.8 13.0 1.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KRH92111.1 - 3.4e-05 24.1 0.1 6.2e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter NYD-SP28_assoc PF14775.6 KRH92111.1 - 0.12 12.5 0.8 0.28 11.3 0.8 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain ATP-synt_8 PF00895.20 KRH92111.1 - 0.2 12.1 0.3 0.2 12.1 0.3 3.4 2 1 1 3 3 3 0 ATP synthase protein 8 FtsX PF02687.21 KRH92111.1 - 3.7 8.1 14.6 7.2 7.2 9.4 2.2 2 0 0 2 2 2 0 FtsX-like permease family Ras PF00071.22 KRH92113.1 - 9.8e-38 129.3 0.3 1.2e-37 129.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH92113.1 - 5.3e-29 100.9 0.1 8.2e-29 100.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH92113.1 - 1.5e-15 57.1 0.3 1.7e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KRH92113.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KRH92113.1 - 4e-06 26.4 0.4 5.2e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.18 KRH92113.1 - 0.00011 21.6 1.0 0.081 12.2 0.4 2.1 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 KRH92113.1 - 0.00015 21.8 0.2 0.36 10.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KRH92113.1 - 0.00021 21.0 0.8 0.00083 19.1 0.1 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KRH92113.1 - 0.00064 19.2 0.4 0.003 17.0 0.2 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KRH92113.1 - 0.0021 17.6 0.3 0.038 13.5 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KRH92113.1 - 0.0075 16.5 0.0 0.0087 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KRH92113.1 - 0.0094 15.5 0.1 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_7 PF12775.7 KRH92113.1 - 0.0098 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF4848 PF16140.5 KRH92113.1 - 0.017 14.7 0.3 0.034 13.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) AAA_24 PF13479.6 KRH92113.1 - 0.04 13.6 0.4 0.072 12.8 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KRH92113.1 - 0.053 13.6 0.5 0.13 12.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KRH92113.1 - 0.054 13.3 0.1 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PMT PF02366.18 KRH92114.1 - 2.3e-61 207.5 22.1 2.7e-61 207.2 22.1 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 KRH92114.1 - 0.51 10.5 21.8 0.05 13.8 16.1 2.2 3 1 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Ni_hydr_CYTB PF01292.20 KRH92114.1 - 8.6 5.9 11.5 5.2 6.6 0.7 3.4 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 rve PF00665.26 KRH92115.1 - 1.8e-15 57.1 0.0 5.8e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92115.1 - 5.3e-05 23.3 4.1 0.00019 21.5 4.1 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH92118.1 - 0.0065 16.7 0.1 0.0092 16.2 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92118.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 KRH92119.1 - 3.1e-12 46.4 2.4 4.7e-12 45.8 2.4 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92119.1 - 0.0031 17.7 1.6 0.0054 16.9 1.6 1.4 1 0 0 1 1 1 1 H2C2 zinc finger MLVIN_C PF18697.1 KRH92120.1 - 0.015 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain NlpE PF04170.12 KRH92120.1 - 0.072 14.1 0.5 0.54 11.3 0.1 2.1 1 1 1 2 2 2 0 NlpE N-terminal domain rve PF00665.26 KRH92122.1 - 5.4e-20 71.8 0.0 9.7e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92122.1 - 6.9e-14 51.7 1.5 6.9e-14 51.7 1.5 2.3 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92122.1 - 1.4e-05 25.2 2.5 3.6e-05 23.9 1.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 KRH92122.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain PhetRS_B1 PF18262.1 KRH92122.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain AIRC PF00731.20 KRH92122.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 AIR carboxylase Gla PF00594.20 KRH92123.1 - 0.092 13.0 0.7 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain UFD1 PF03152.14 KRH92125.1 - 7.5e-44 149.2 0.0 9.9e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 KRH92125.1 - 0.047 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 MBOAT PF03062.19 KRH92127.1 - 1.3e-07 31.3 15.3 1.5e-06 27.9 1.2 2.4 3 0 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family Peroxin-13_N PF04088.13 KRH92127.1 - 0.045 14.0 0.1 0.09 13.1 0.1 1.5 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Cons_hypoth95 PF03602.15 KRH92129.1 - 2.3e-12 46.9 0.0 2.9e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KRH92129.1 - 2.5e-12 46.7 0.0 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KRH92129.1 - 1.7e-08 35.0 0.0 3.3e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KRH92129.1 - 8.3e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 KRH92129.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.10 KRH92129.1 - 5.5e-05 22.8 0.2 0.00013 21.6 0.1 1.6 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KRH92129.1 - 5.7e-05 23.0 0.9 9.7e-05 22.2 0.9 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRH92129.1 - 0.00084 19.9 0.0 0.002 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 KRH92129.1 - 0.0016 17.9 0.4 0.0025 17.2 0.1 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Ubie_methyltran PF01209.18 KRH92129.1 - 0.0021 17.4 0.1 0.0027 17.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltrans_SAM PF10672.9 KRH92129.1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase DUF43 PF01861.16 KRH92129.1 - 0.016 14.4 0.2 0.026 13.7 0.2 1.5 1 1 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain EB1 PF03271.17 KRH92129.1 - 0.05 13.9 0.7 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 EB1-like C-terminal motif Methyltransf_16 PF10294.9 KRH92129.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cytochrom_B558a PF05038.13 KRH92129.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit TBCC PF07986.12 KRH92130.1 - 4e-07 29.8 4.2 5.3e-07 29.4 1.0 2.4 2 1 0 2 2 2 1 Tubulin binding cofactor C CCD48 PF15799.5 KRH92130.1 - 0.066 11.5 0.1 0.069 11.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 PBP_dimer PF03717.15 KRH92130.1 - 0.75 10.1 4.4 12 6.2 0.4 2.1 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain mRNA_cap_enzyme PF01331.19 KRH92131.1 - 1.5e-24 87.0 4.8 4.7e-24 85.3 4.8 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 KRH92131.1 - 0.00013 21.7 0.5 0.0017 18.0 0.4 2.1 1 1 1 2 2 2 1 ATP dependent DNA ligase domain Rep_fac_C PF08542.11 KRH92132.1 - 0.021 15.2 0.5 0.095 13.1 0.1 2.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain SAM_KSR1 PF13543.6 KRH92132.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.3 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 PRESAN PF09687.10 KRH92132.1 - 0.035 14.7 0.2 0.035 14.7 0.2 1.5 2 0 0 2 2 2 0 Plasmodium RESA N-terminal AsnA PF03590.15 KRH92132.1 - 0.049 13.4 0.3 0.079 12.7 0.3 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase LZ3wCH PF18517.1 KRH92132.1 - 0.057 13.5 0.0 1.1 9.4 0.0 2.4 1 1 1 2 2 2 0 Leucine zipper with capping helix domain NFACT-C PF11923.8 KRH92134.1 - 9.1e-10 38.4 0.1 2.5e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 NFACT protein C-terminal domain Helicase_C PF00271.31 KRH92135.1 - 2e-13 50.7 0.0 4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DDE_Tnp_IS1595 PF12762.7 KRH92137.1 - 8.2e-18 64.9 0.1 1.2e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.6 KRH92137.1 - 2.7e-06 27.7 1.1 7e-06 26.3 0.2 2.0 2 0 0 2 2 2 1 DDE domain DDE_3 PF13358.6 KRH92137.1 - 1.9e-05 24.5 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5557 PF17712.1 KRH92137.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5557) DDE_3 PF13358.6 KRH92138.1 - 0.00021 21.1 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4010 PF13194.6 KRH92139.1 - 0.0049 16.6 0.2 0.0079 15.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) DUF4834 PF16118.5 KRH92139.1 - 0.034 15.1 0.0 0.034 15.1 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) LisH PF08513.11 KRH92140.1 - 3.5e-08 33.1 0.3 6.5e-08 32.3 0.3 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 KRH92140.1 - 0.13 12.6 0.9 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 FOP N terminal dimerisation domain DUF357 PF04010.13 KRH92140.1 - 0.13 12.3 0.7 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) LisH_2 PF16045.5 KRH92140.1 - 1.9 7.6 4.6 0.39 9.8 0.3 2.0 2 0 0 2 2 2 0 LisH Ribosomal_S28e PF01200.18 KRH92142.1 - 3.8e-15 55.6 0.1 4.3e-15 55.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e AAA PF00004.29 KRH92143.1 - 3e-24 85.9 0.0 1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KRH92143.1 - 1.2e-08 35.2 0.0 2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KRH92143.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KRH92143.1 - 0.00048 20.6 0.0 0.00091 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KRH92143.1 - 0.00048 20.3 0.0 0.00089 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KRH92143.1 - 0.00058 19.6 0.0 0.037 13.7 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KRH92143.1 - 0.0013 18.2 0.0 0.75 9.1 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KRH92143.1 - 0.0022 18.3 0.1 2.7 8.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 KRH92143.1 - 0.0054 16.8 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KRH92143.1 - 0.011 15.8 0.0 0.077 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KRH92143.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KRH92143.1 - 0.014 15.8 0.0 0.078 13.4 0.0 2.4 2 2 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KRH92143.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KRH92143.1 - 0.18 11.6 0.0 0.53 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain GCP_C_terminal PF04130.13 KRH92147.1 - 2.4e-18 66.7 8.1 9.4e-18 64.7 8.1 1.8 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal V-ATPase_H_C PF11698.8 KRH92147.1 - 0.027 14.6 0.9 0.063 13.4 0.9 1.7 1 0 0 1 1 1 0 V-ATPase subunit H RNA_pol_Rpb1_5 PF04998.17 KRH92148.1 - 8.3e-21 74.6 0.1 1.1e-20 74.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R PF05001.13 KRH92148.1 - 2.3e-12 46.5 81.3 0.0017 18.6 3.4 8.0 1 1 9 10 10 10 8 RNA polymerase Rpb1 C-terminal repeat INCENP_ARK-bind PF03941.15 KRH92149.1 - 0.0097 15.8 1.7 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Lipase_3 PF01764.25 KRH92150.1 - 0.0096 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KRH92150.1 - 0.024 13.9 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KRH92150.1 - 0.026 14.3 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4286 PF14114.6 KRH92150.1 - 0.04 14.4 0.4 0.57 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DUF4224 PF13986.6 KRH92150.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF5092 PF17010.5 KRH92151.1 - 2.3e-38 131.7 1.9 1.1e-28 100.3 0.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5092) UCH PF00443.29 KRH92152.1 - 2.2e-32 112.6 10.5 3.1e-32 112.1 10.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH92152.1 - 1.2e-08 34.9 14.4 1.2e-06 28.3 14.4 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MOZ_SAS PF01853.18 KRH92153.1 - 3e-63 212.7 3.0 3e-63 212.7 3.0 1.5 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KRH92153.1 - 2.1e-09 36.8 0.2 5.8e-09 35.4 0.2 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KRH92153.1 - 2e-06 28.1 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRH92153.1 - 0.0051 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KRH92153.1 - 0.0063 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family tRNA-synt_1g PF09334.11 KRH92154.1 - 2.6e-13 49.5 0.0 5.7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KRH92154.1 - 1.2e-10 41.2 0.1 2.3e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 KRH92154.1 - 1.4e-10 40.1 0.2 1.7e-09 36.5 0.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KRH92154.1 - 0.0036 16.3 0.3 0.024 13.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) Acyltransferase PF01553.21 KRH92155.1 - 1.6e-19 69.9 0.1 2.5e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase GvpL_GvpF PF06386.11 KRH92156.1 - 0.14 12.1 4.5 0.17 11.7 4.5 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF LMBR1 PF04791.16 KRH92156.1 - 4.1 6.2 5.7 4.7 6.0 5.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ATPase_2 PF01637.18 KRH92157.1 - 8.2e-06 25.9 0.4 1e-05 25.6 0.4 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KRH92157.1 - 0.0006 19.8 0.4 0.0011 19.0 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH92157.1 - 0.0013 19.1 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KRH92157.1 - 0.0025 17.3 0.1 0.0037 16.7 0.1 1.3 1 1 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 KRH92157.1 - 0.0056 16.7 0.2 0.0076 16.3 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 KRH92157.1 - 0.01 14.9 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 KRH92157.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KRH92157.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 KRH92157.1 - 0.017 14.6 0.4 0.56 9.7 0.0 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KRH92157.1 - 0.024 14.3 0.6 0.063 13.0 0.6 1.6 1 1 0 1 1 1 0 AAA domain DUF4623 PF15416.6 KRH92157.1 - 0.029 13.0 0.0 0.036 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) AAA_22 PF13401.6 KRH92157.1 - 0.033 14.5 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KRH92157.1 - 0.044 14.0 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KRH92157.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family Holin_BhlA PF10960.8 KRH92157.1 - 0.14 12.2 0.9 0.71 9.9 0.5 2.0 2 0 0 2 2 2 0 BhlA holin family AAA_29 PF13555.6 KRH92157.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Far-17a_AIG1 PF04750.14 KRH92161.1 - 3.3e-09 36.4 13.2 4.3e-09 36.0 13.2 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein RELT PF12606.8 KRH92161.1 - 0.046 12.7 0.1 0.093 11.7 0.1 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 CBFD_NFYB_HMF PF00808.23 KRH92162.1 - 1e-05 25.7 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 KRH92162.1 - 0.07 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 KRH92162.1 - 0.077 13.0 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated Ricin_B_lectin PF00652.22 KRH92163.1 - 0.00032 20.9 0.4 0.0005 20.3 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KRH92163.1 - 0.071 13.8 0.4 0.34 11.7 0.2 2.1 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RVT_1 PF00078.27 KRH92165.1 - 0.00048 19.7 0.1 0.00059 19.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSCB_C PF07743.13 KRH92167.1 - 1.1 9.8 7.4 12 6.5 7.3 2.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain RVT_1 PF00078.27 KRH92168.1 - 6.9e-22 78.0 0.2 1e-21 77.5 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH92168.1 - 3.3e-05 23.8 1.5 5.8e-05 23.1 0.1 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92169.1 - 0.0095 15.5 0.0 0.011 15.3 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B277 PF17623.2 KRH92170.1 - 0.0068 15.5 0.5 0.0085 15.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF4868 PF16162.5 KRH92170.1 - 0.021 14.7 1.3 0.026 14.5 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4868) DUF5095 PF17016.5 KRH92171.1 - 3.1e-48 164.6 23.4 3.5e-48 164.4 23.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5095) Maf1 PF09174.10 KRH92172.1 - 6.3e-05 23.2 9.3 6.3e-05 23.2 9.3 2.0 1 1 1 2 2 2 2 Maf1 regulator Actin PF00022.19 KRH92173.1 - 1.4e-06 27.2 0.0 1.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Actin SGS PF05002.15 KRH92173.1 - 0.007 16.4 0.6 0.018 15.2 0.2 1.9 2 1 0 2 2 2 1 SGS domain rve PF00665.26 KRH92175.1 - 5.6e-20 71.7 0.0 9.1e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92175.1 - 0.00059 20.1 0.9 0.0012 19.0 0.1 1.9 2 1 0 2 2 2 1 DDE domain rve_3 PF13683.6 KRH92175.1 - 0.00093 18.9 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain SBP_bac_5 PF00496.22 KRH92175.1 - 0.0017 17.4 0.5 0.0029 16.6 0.2 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle Synapsin PF02078.16 KRH92175.1 - 0.021 15.1 0.1 0.73 10.1 0.0 2.2 2 0 0 2 2 2 0 Synapsin, N-terminal domain RE_MamI PF09567.10 KRH92177.1 - 0.14 11.8 2.4 0.24 11.0 0.8 1.8 2 0 0 2 2 2 0 MamI restriction endonuclease DUF1132 PF06575.12 KRH92177.1 - 0.22 11.9 4.8 1.3 9.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1132) Gla PF00594.20 KRH92178.1 - 0.074 13.3 0.8 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain RT_RNaseH_2 PF17919.1 KRH92179.1 - 4.8e-18 65.0 0.0 6.3e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92179.1 - 9.3e-18 64.5 0.0 1.1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92180.1 - 5.6e-06 26.4 0.7 8.9e-06 25.7 0.7 1.3 1 1 0 1 1 1 1 Integrase zinc binding domain Peptidase_C98 PF15499.6 KRH92180.1 - 0.013 15.0 0.3 0.013 15.0 0.3 1.0 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase gag_pre-integrs PF13976.6 KRH92180.1 - 0.015 15.2 1.2 0.02 14.7 1.2 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain Arf PF00025.21 KRH92181.1 - 7.2e-33 113.5 0.1 3.6e-28 98.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KRH92181.1 - 2.4e-10 40.1 2.0 2.4e-06 26.9 0.3 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KRH92181.1 - 7.3e-09 35.3 0.0 9.4e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KRH92181.1 - 3.3e-07 30.4 0.0 6.3e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KRH92181.1 - 6.7e-06 25.8 0.5 0.097 12.2 0.0 3.2 2 1 1 3 3 3 3 Elongation factor Tu GTP binding domain Roc PF08477.13 KRH92181.1 - 7.1e-06 26.2 0.2 0.00011 22.4 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KRH92181.1 - 0.00043 19.7 0.1 0.0016 17.8 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KRH92181.1 - 0.0019 17.8 0.1 0.0055 16.3 0.1 1.8 1 1 0 1 1 1 1 Ras family DLIC PF05783.11 KRH92181.1 - 0.0058 15.5 0.4 0.99 8.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) FeoB_N PF02421.18 KRH92181.1 - 0.01 15.4 0.4 3.7 7.1 0.2 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KRH92181.1 - 0.058 13.3 0.1 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Thymidylate_kin PF02223.17 KRH92181.1 - 0.1 12.3 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase PduV-EutP PF10662.9 KRH92181.1 - 0.11 12.2 0.4 0.38 10.5 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.28 KRH92182.1 - 6.8e-58 196.6 2.6 2.3e-34 119.1 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RT_RNaseH_2 PF17919.1 KRH92183.1 - 1.3e-28 98.9 0.0 2.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92183.1 - 5.6e-27 94.1 0.0 1e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92183.1 - 3e-06 27.2 0.6 1e-05 25.5 0.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain MafB19-deam PF14437.6 KRH92183.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 MafB19-like deaminase gag_pre-integrs PF13976.6 KRH92183.1 - 0.0043 16.9 0.1 0.0085 15.9 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.27 KRH92184.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4H2 PF10146.9 KRH92185.1 - 0.0088 16.4 3.4 0.012 16.0 3.4 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Thymidylate_kin PF02223.17 KRH92186.1 - 1e-30 106.8 0.1 1.1e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KRH92186.1 - 0.0004 20.9 0.0 0.001 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KRH92186.1 - 0.00074 19.6 0.7 0.0012 18.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KRH92186.1 - 0.0012 19.1 0.0 0.0039 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KRH92186.1 - 0.0018 18.3 3.2 0.011 15.7 3.2 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea dNK PF01712.19 KRH92186.1 - 0.012 15.4 0.2 0.087 12.7 0.2 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase TIP49 PF06068.13 KRH92186.1 - 0.014 14.7 0.1 0.058 12.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain G-alpha PF00503.20 KRH92186.1 - 0.017 14.3 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 KRH92186.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KRH92186.1 - 0.039 13.4 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family KAP_NTPase PF07693.14 KRH92186.1 - 0.061 12.5 0.0 0.062 12.5 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain PRK PF00485.18 KRH92186.1 - 0.076 12.7 0.2 0.24 11.1 0.0 1.8 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KRH92186.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 KRH92186.1 - 0.1 12.3 0.8 1.9 8.1 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase TsaE PF02367.17 KRH92186.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KRH92186.1 - 0.19 12.1 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RT_RNaseH PF17917.1 KRH92187.1 - 1.1e-38 131.7 0.0 2.1e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92187.1 - 1.8e-33 114.6 0.0 3.2e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92187.1 - 1.1e-15 57.5 0.4 2.3e-15 56.4 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH92187.1 - 6.2e-12 45.8 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92187.1 - 0.0018 18.5 0.3 0.0059 16.8 0.0 1.9 2 0 0 2 2 2 1 DDE domain zf-H2C2 PF09337.10 KRH92187.1 - 0.015 15.5 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger YoeB_toxin PF06769.14 KRH92187.1 - 0.098 12.7 0.0 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system DDE_3 PF13358.6 KRH92189.1 - 1.1e-05 25.2 0.5 1.5e-05 24.8 0.5 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH92192.1 - 2.8e-08 33.9 0.1 3.9e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Transposase Arg_repressor PF01316.21 KRH92192.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_33 PF13592.6 KRH92192.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Nop PF01798.18 KRH92193.1 - 3.1e-46 157.7 0.6 3.8e-46 157.4 0.6 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF3055 PF11256.8 KRH92193.1 - 0.051 13.8 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3055) CorA PF01544.18 KRH92194.1 - 4.1e-26 92.0 9.2 1.2e-21 77.4 1.7 2.0 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Asp_protease_2 PF13650.6 KRH92195.1 - 7.6e-06 26.5 0.0 9.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH92195.1 - 0.005 17.4 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92195.1 - 0.009 15.8 0.0 0.0095 15.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH92195.1 - 0.038 13.5 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Diphthamide_syn PF01866.17 KRH92196.1 - 1.2e-19 70.9 0.7 1.2e-19 70.9 0.7 1.3 2 0 0 2 2 2 1 Putative diphthamide synthesis protein EDR1 PF14381.6 KRH92196.1 - 0.0058 16.4 1.5 0.089 12.5 0.3 2.0 1 1 1 2 2 2 2 Ethylene-responsive protein kinase Le-CTR1 DHHC PF01529.20 KRH92198.1 - 2.3e-28 99.0 12.1 2.3e-28 99.0 12.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase MIP PF00230.20 KRH92200.1 - 5.9e-31 107.9 15.3 1.6e-30 106.5 15.3 1.6 1 1 0 1 1 1 1 Major intrinsic protein NVEALA PF14055.6 KRH92200.1 - 0.14 12.2 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 NVEALA protein Vpu PF00558.19 KRH92200.1 - 0.76 9.6 3.9 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Vpu protein Phage_holin_3_1 PF05106.12 KRH92200.1 - 7.3 7.1 10.3 3.2 8.2 2.8 3.4 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) Ribosomal_S8e PF01201.22 KRH92202.1 - 5.6e-45 152.9 4.1 6.8e-45 152.6 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Asn_synthase PF00733.21 KRH92203.1 - 2.1e-11 44.1 0.0 9.1e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase ATP_bind_3 PF01171.20 KRH92203.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 PP-loop family GCS PF03074.16 KRH92204.1 - 4.6e-36 124.9 2.3 3.6e-26 92.4 4.0 2.2 2 0 0 2 2 2 2 Glutamate-cysteine ligase PGK PF00162.19 KRH92205.1 - 1.5e-23 83.4 1.3 2.7e-20 72.7 0.1 2.1 1 1 1 2 2 2 2 Phosphoglycerate kinase Asp_protease_2 PF13650.6 KRH92206.1 - 2.1e-05 25.1 0.0 2.2e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH92206.1 - 0.0079 16.7 0.0 0.0088 16.6 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92206.1 - 0.043 13.6 0.0 0.044 13.6 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH92206.1 - 0.1 12.2 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase BK_channel_a PF03493.18 KRH92209.1 - 0.098 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit DUF1400 PF07176.11 KRH92209.1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) ADK_lid PF05191.14 KRH92210.1 - 0.044 13.8 0.6 0.096 12.7 0.1 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF2201_N PF13203.6 KRH92213.1 - 0.02 14.5 0.5 0.027 14.1 0.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.12 KRH92214.1 - 1.7 8.0 20.0 2.2 7.6 20.0 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KRH92214.1 - 3.6 5.7 17.7 4.5 5.4 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KRH92214.1 - 7.4 4.7 13.9 9.4 4.4 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM75 PF14650.6 KRH92214.1 - 8.5 5.8 10.9 12 5.3 10.9 1.2 1 0 0 1 1 1 0 FAM75 family LSM PF01423.22 KRH92215.1 - 4.2e-07 29.5 1.0 5e-07 29.3 1.0 1.1 1 0 0 1 1 1 1 LSM domain DUF365 PF04033.12 KRH92216.1 - 0.14 12.4 3.3 0.38 11.1 3.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Antimicrobial19 PF08225.11 KRH92216.1 - 2.2 8.0 4.4 33 4.2 0.1 3.2 3 1 0 3 3 3 0 Pseudin antimicrobial peptide DDE_Tnp_IS1595 PF12762.7 KRH92217.1 - 4.2e-22 78.8 0.0 5.9e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain BAAT_C PF08840.11 KRH92218.1 - 0.026 14.4 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KRH92218.1 - 0.058 13.2 0.2 3.2 7.5 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KRH92218.1 - 0.08 12.6 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Nse4_C PF08743.10 KRH92219.1 - 1.2e-16 60.7 0.3 1.2e-16 60.7 0.3 2.0 2 1 1 3 3 3 1 Nse4 C-terminal PBS_linker_poly PF00427.21 KRH92219.1 - 0.073 13.1 2.4 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide RT_RNaseH_2 PF17919.1 KRH92220.1 - 5.3e-11 42.4 0.0 5.5e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92220.1 - 1.9e-07 31.3 0.0 2.1e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92221.1 - 2.1e-14 53.6 0.1 2.5e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH92223.1 - 2.2e-10 40.7 0.9 4e-10 39.9 0.3 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92223.1 - 1.4e-05 25.1 0.2 2.6e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain CDtoxinA PF03498.14 KRH92224.1 - 0.00027 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain Curto_V2 PF07325.11 KRH92224.1 - 0.23 11.3 3.7 0.16 11.8 1.8 1.6 2 0 0 2 2 2 0 Curtovirus V2 protein PX PF00787.24 KRH92225.1 - 0.00033 20.6 2.2 0.0008 19.4 2.2 1.6 1 0 0 1 1 1 1 PX domain Toxin-JAB1 PF15659.6 KRH92225.1 - 0.14 12.5 6.1 4.5 7.7 0.2 2.4 2 0 0 2 2 2 0 JAB-like toxin 1 Integrase_H2C2 PF17921.1 KRH92226.1 - 4.2e-09 36.4 0.1 8.8e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KRH92226.1 - 1.6e-06 28.6 0.2 3.7e-06 27.4 0.2 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92226.1 - 2.9e-05 24.6 0.1 8.2e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH92226.1 - 8.7e-05 22.8 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 KRH92226.1 - 0.00014 22.0 0.4 0.0003 20.9 0.4 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RVP_2 PF08284.11 KRH92226.1 - 0.00022 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KRH92226.1 - 0.00089 19.2 2.0 0.00089 19.2 2.0 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF1758 PF05585.12 KRH92226.1 - 0.0076 16.0 0.7 0.013 15.3 0.1 1.6 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 KRH92226.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2_10 PF16588.5 KRH92226.1 - 0.15 11.8 2.1 0.39 10.5 2.1 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger DDE_3 PF13358.6 KRH92227.1 - 4.8e-12 45.9 0.4 8.2e-12 45.1 0.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH92227.1 - 1.2e-09 38.2 2.9 3.6e-08 33.5 0.1 2.9 3 0 0 3 3 3 1 Transposase HTH_IclR PF09339.10 KRH92227.1 - 0.0079 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.6 KRH92227.1 - 0.0094 16.6 0.0 0.039 14.6 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 KRH92227.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_5 PF01022.20 KRH92227.1 - 0.021 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 KRH92227.1 - 0.026 14.3 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 KRH92227.1 - 0.05 13.7 0.2 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix DUF3408 PF11888.8 KRH92227.1 - 0.077 13.1 0.9 0.15 12.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TrmB PF01978.19 KRH92227.1 - 0.082 12.8 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-met PF12874.7 KRH92228.1 - 1.4e-05 25.3 4.9 2.5e-05 24.5 4.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SF3A2 PF16835.5 KRH92228.1 - 2e-05 24.8 0.9 4.3e-05 23.8 0.9 1.7 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-C2H2_2 PF12756.7 KRH92228.1 - 0.00033 20.9 0.7 0.00058 20.1 0.7 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KRH92228.1 - 0.0031 17.8 6.6 0.0065 16.7 6.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF5611 PF18446.1 KRH92228.1 - 0.012 16.4 4.2 0.051 14.5 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5611) Mu-like_Com PF10122.9 KRH92228.1 - 0.019 14.4 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com FAS_meander PF17951.1 KRH92229.1 - 0.053 13.3 0.4 0.056 13.3 0.4 1.0 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain RNA_pol_Rpb2_7 PF04560.20 KRH92230.1 - 2.9e-22 78.8 0.7 2.1e-21 76.1 0.7 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_6 PF00562.28 KRH92230.1 - 6.7e-20 71.5 0.1 9.3e-20 71.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Pentapeptide_2 PF01469.18 KRH92230.1 - 3.7e-05 23.5 6.6 5.9e-05 22.9 6.6 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) NTP_transferase PF00483.23 KRH92231.1 - 0.0072 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Peptidase_C97 PF05903.14 KRH92232.1 - 1.6e-36 125.4 0.5 1.8e-36 125.2 0.5 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KRH92232.1 - 0.0012 19.2 0.2 0.0016 18.7 0.2 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase MICSWaP PF17018.5 KRH92234.1 - 2.8e-66 222.8 0.5 3.5e-66 222.5 0.5 1.1 1 0 0 1 1 1 1 Spore wall protein MS_channel PF00924.18 KRH92236.1 - 2.1e-16 60.1 3.1 3.2e-16 59.5 3.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KRH92236.1 - 0.0038 16.7 0.4 0.0038 16.7 0.4 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KRH92236.1 - 0.011 15.6 4.0 0.024 14.6 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain ABC_membrane_3 PF13748.6 KRH92236.1 - 3.8 6.7 9.0 2.3 7.4 2.2 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region AMP-binding_C PF13193.6 KRH92237.1 - 6.2e-18 65.5 0.1 1.4e-17 64.4 0.1 1.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-rbx1 PF12678.7 KRH92238.1 - 3.1e-11 43.4 0.5 5.3e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KRH92238.1 - 3.6e-09 36.8 1.9 6.1e-09 36.1 1.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KRH92238.1 - 4.5e-07 29.6 1.6 7.4e-07 28.9 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH92238.1 - 4.1e-06 26.6 0.5 7.3e-06 25.8 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KRH92238.1 - 5.9e-06 26.0 0.5 1.2e-05 25.1 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KRH92238.1 - 8e-06 25.8 1.1 1.2e-05 25.2 1.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 KRH92238.1 - 8.8e-05 22.7 0.6 0.00019 21.6 0.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family zf-RING_UBOX PF13445.6 KRH92238.1 - 0.00011 22.2 2.8 0.00017 21.6 0.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KRH92238.1 - 0.00017 21.4 1.8 0.00027 20.7 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KRH92238.1 - 0.0014 18.4 0.5 0.0014 18.4 0.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 KRH92238.1 - 0.0015 18.1 1.8 0.0027 17.3 1.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KRH92238.1 - 0.0016 18.5 0.6 0.0037 17.4 0.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KRH92238.1 - 0.003 17.4 2.0 0.0057 16.5 2.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KRH92238.1 - 0.0044 16.8 1.6 0.011 15.5 1.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KRH92238.1 - 0.014 15.4 0.6 0.028 14.5 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 KRH92238.1 - 0.047 14.0 3.2 0.08 13.3 3.2 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KRH92238.1 - 0.18 12.0 4.6 0.38 10.9 4.6 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KRH92238.1 - 1.1 9.5 5.2 6 7.1 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-B_box PF00643.24 KRH92239.1 - 3.1e-12 46.4 18.9 2.2e-06 27.7 6.9 2.4 2 0 0 2 2 2 2 B-box zinc finger zinc-ribbons_6 PF07191.12 KRH92239.1 - 1.7 8.7 10.8 1.2 9.1 2.2 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-FPG_IleRS PF06827.14 KRH92239.1 - 2.4 8.1 6.9 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-UBR PF02207.20 KRH92239.1 - 6.4 7.0 20.4 0.26 11.5 5.4 3.1 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DEAD PF00270.29 KRH92241.1 - 8.5e-07 28.9 0.1 1.2e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_7 PF12775.7 KRH92241.1 - 0.063 12.8 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Coronavirus_5 PF05528.11 KRH92242.1 - 0.0041 17.1 0.2 0.0054 16.7 0.2 1.2 1 0 0 1 1 1 1 Coronavirus gene 5 protein CBP4 PF07960.11 KRH92242.1 - 0.31 10.9 7.6 0.39 10.6 7.6 1.3 1 1 0 1 1 1 0 CBP4 Mif2_N PF15624.6 KRH92242.1 - 0.41 11.4 8.3 0.45 11.2 8.3 1.0 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal XPG_N PF00752.17 KRH92243.1 - 7.3e-10 39.2 0.0 3.7e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain PIN_8 PF18476.1 KRH92243.1 - 0.041 13.7 0.2 0.1 12.4 0.2 1.6 1 1 0 1 1 1 0 PIN like domain zf-RVT PF13966.6 KRH92243.1 - 0.057 14.1 0.0 0.14 12.9 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-C3HC4_3 PF13920.6 KRH92243.1 - 0.17 11.8 0.6 0.17 11.8 0.6 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CBP4 PF07960.11 KRH92244.1 - 0.45 10.4 10.1 0.57 10.0 10.1 1.3 1 1 0 1 1 1 0 CBP4 DUF3573 PF12097.8 KRH92244.1 - 2.4 6.9 6.9 2.3 7.0 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) XPG_N PF00752.17 KRH92245.1 - 1e-09 38.8 0.0 5.1e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain zf-RVT PF13966.6 KRH92245.1 - 0.028 15.1 0.0 0.083 13.6 0.0 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase APS_kinase PF01583.20 KRH92245.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-C3HC4_3 PF13920.6 KRH92245.1 - 0.17 11.8 0.6 0.17 11.8 0.6 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RT_RNaseH_2 PF17919.1 KRH92246.1 - 5e-30 103.5 0.0 1.3e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92246.1 - 9.9e-26 90.1 0.0 2.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92246.1 - 1.2e-09 38.0 0.3 2.1e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.23 KRH92247.1 - 8.2e-18 64.6 0.5 1.1e-13 51.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NGP1NT PF08153.12 KRH92247.1 - 1.8e-13 50.8 1.5 3.2e-13 50.0 1.5 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain FeoB_N PF02421.18 KRH92247.1 - 8.9e-09 35.1 0.8 0.00014 21.4 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KRH92247.1 - 3.2e-06 27.2 0.1 9.5e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KRH92247.1 - 0.00023 20.8 0.0 0.025 14.1 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KRH92247.1 - 0.0041 16.6 0.3 0.75 9.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF2375 PF09558.10 KRH92247.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2375) MMR_HSR1_Xtn PF16897.5 KRH92247.1 - 0.0055 16.7 0.4 0.016 15.3 0.2 1.9 2 0 0 2 2 1 1 C-terminal region of MMR_HSR1 domain cobW PF02492.19 KRH92247.1 - 0.014 15.0 0.1 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KRH92247.1 - 0.066 13.4 0.1 2 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Carot_N PF09150.10 KRH92247.1 - 0.068 13.0 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Orange carotenoid protein, N-terminal MeaB PF03308.16 KRH92247.1 - 0.16 10.9 0.0 0.4 9.6 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KRH92247.1 - 0.18 11.1 2.6 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 KRH92247.1 - 2.9 7.9 8.2 5.7 7.0 0.1 3.6 2 2 0 3 3 3 0 Dynamin family Proteasome PF00227.26 KRH92248.1 - 1.8e-29 102.6 0.0 2.5e-29 102.1 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit CBP_BcsR PF10945.8 KRH92248.1 - 0.0045 16.4 0.1 2.1 7.9 0.0 2.6 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsR Proteasome_A_N PF10584.9 KRH92248.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DUF5600 PF18150.1 KRH92248.1 - 0.028 15.0 0.6 0.44 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) DNA_photolyase PF00875.18 KRH92250.1 - 3.6e-07 30.3 0.0 1.1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Spo7 PF03907.13 KRH92251.1 - 0.0078 15.7 0.3 0.0088 15.5 0.3 1.1 1 0 0 1 1 1 1 Spo7-like protein Sigma70_r1_1 PF03979.14 KRH92251.1 - 0.013 15.6 1.3 0.013 15.6 1.3 2.9 2 1 0 2 2 2 0 Sigma-70 factor, region 1.1 STI1 PF17830.1 KRH92252.1 - 0.0027 17.6 7.2 0.006 16.5 1.0 3.9 2 2 2 4 4 4 1 STI1 domain Ldh_1_N PF00056.23 KRH92252.1 - 6.1 6.9 5.7 32 4.6 0.1 3.5 2 1 2 4 4 4 0 lactate/malate dehydrogenase, NAD binding domain RicinB_lectin_2 PF14200.6 KRH92254.1 - 1.1e-06 29.3 0.0 2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KRH92254.1 - 5.3e-05 23.5 0.0 6.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain SET_assoc PF11767.8 KRH92254.1 - 0.002 17.7 0.5 0.0065 16.1 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated DUF2972 PF11186.8 KRH92254.1 - 0.063 13.2 0.3 0.094 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) TRM PF02005.16 KRH92255.1 - 9.5e-65 219.2 0.7 1.2e-64 218.9 0.7 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MarR PF01047.22 KRH92255.1 - 0.1 12.6 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 MarR family rve PF00665.26 KRH92258.1 - 4e-19 69.0 0.0 6.5e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92258.1 - 0.00093 19.4 0.1 0.003 17.8 0.0 1.8 2 1 0 2 2 2 1 DDE domain rve_3 PF13683.6 KRH92258.1 - 0.0016 18.2 0.1 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain SBP_bac_5 PF00496.22 KRH92258.1 - 0.0034 16.4 0.8 0.0066 15.4 0.6 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF1670 PF07900.11 KRH92258.1 - 0.01 15.2 0.3 0.016 14.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1670) MLVIN_C PF18697.1 KRH92258.1 - 0.089 12.9 0.3 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RT_RNaseH_2 PF17919.1 KRH92259.1 - 5.5e-30 103.4 0.0 1.9e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92259.1 - 1.1e-25 90.0 0.0 2.6e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92259.1 - 6.3e-10 38.9 0.2 1.1e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH92260.1 - 5.5e-30 103.4 0.0 1.9e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92260.1 - 1.1e-25 89.9 0.0 2.6e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92260.1 - 6.3e-10 38.9 0.2 1.1e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NTP_transf_2 PF01909.23 KRH92261.1 - 1.1e-10 41.7 1.1 2.6e-10 40.4 0.7 2.1 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.17 KRH92261.1 - 5.3e-06 25.6 0.4 1.1e-05 24.6 0.4 1.4 1 1 0 1 1 1 1 Poly(A) polymerase central domain LMBR1 PF04791.16 KRH92261.1 - 0.028 13.4 0.7 0.035 13.0 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_pol_B_palm PF14792.6 KRH92261.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm Hid1 PF12722.7 KRH92261.1 - 5.4 5.0 16.2 7.1 4.6 16.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 KRH92262.1 - 1.2e-62 211.7 0.1 1.4e-62 211.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92262.1 - 1.4e-36 126.1 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KRH92262.1 - 0.00065 19.7 0.0 0.0083 16.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KRH92262.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KRH92262.1 - 0.0079 15.2 0.0 0.042 12.8 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KRH92262.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 KRH92262.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KRH92262.1 - 0.12 11.7 0.1 0.4 10.0 0.0 1.8 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family rve PF00665.26 KRH92264.1 - 7.6e-20 71.3 0.0 1.4e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92264.1 - 2.2e-13 50.1 1.1 2.2e-13 50.1 1.1 2.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92264.1 - 0.00022 21.4 0.7 0.00022 21.4 0.7 2.6 3 0 0 3 3 3 1 H2C2 zinc finger rve_3 PF13683.6 KRH92264.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain SEP PF08059.13 KRH92264.1 - 0.055 14.0 0.7 0.18 12.4 0.4 2.1 3 0 0 3 3 3 0 SEP domain PhetRS_B1 PF18262.1 KRH92264.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Ribosomal_L2_C PF03947.18 KRH92265.1 - 1.4e-41 141.6 1.0 3.2e-41 140.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KRH92265.1 - 1.3e-09 37.9 0.3 1.5e-08 34.5 0.2 2.6 2 1 1 3 3 3 1 Ribosomal Proteins L2, RNA binding domain GCP_N_terminal PF17681.1 KRH92267.1 - 6.2e-15 55.6 1.5 9.6e-15 55.0 1.5 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal ABC2_membrane PF01061.24 KRH92270.1 - 0.00018 21.0 23.3 0.0003 20.3 23.3 1.4 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane PF01061.24 KRH92271.1 - 2.2e-05 24.0 22.4 3e-05 23.6 22.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter TMCCDC2 PF15844.5 KRH92271.1 - 1.7 8.5 5.4 0.38 10.7 0.2 2.2 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Helicase_C PF00271.31 KRH92272.1 - 4.3e-25 88.2 2.8 7.1e-23 81.1 0.1 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 KRH92272.1 - 9.7e-22 77.6 0.2 1.7e-21 76.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH92272.1 - 6.4e-05 23.0 1.5 0.00012 22.2 1.5 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KRH92272.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF2268 PF10026.9 KRH92272.1 - 0.059 12.9 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RNR_N PF08343.10 KRH92272.1 - 0.072 13.1 0.0 5.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal zf-DBF PF07535.12 KRH92273.1 - 1.1e-17 63.8 3.2 2.1e-17 63.0 3.2 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.10 KRH92273.1 - 0.0045 17.2 0.7 0.0078 16.4 0.4 1.6 1 1 0 1 1 1 1 Dfp1/Him1, central region Ank_2 PF12796.7 KRH92274.1 - 1.1e-09 38.7 0.6 8.5e-09 35.9 0.6 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KRH92274.1 - 1.3e-07 31.7 1.4 0.00066 20.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KRH92274.1 - 1.1e-06 28.4 0.6 0.093 13.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KRH92274.1 - 2.2e-06 27.8 0.1 5.1e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KRH92274.1 - 8.9e-05 23.0 1.5 0.034 14.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Pkinase PF00069.25 KRH92275.1 - 3.3e-53 180.7 2.7 4.3e-53 180.4 2.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92275.1 - 3.8e-30 105.0 0.0 5.9e-30 104.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KRH92275.1 - 0.0002 21.4 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KRH92275.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KRH92275.1 - 0.0016 18.1 0.3 0.78 9.3 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KRH92275.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KRH92275.1 - 0.014 15.0 1.0 0.024 14.2 1.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RT_RNaseH PF17917.1 KRH92276.1 - 1.3e-24 86.5 0.4 4e-24 84.9 0.2 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92276.1 - 4e-24 84.6 0.1 9.8e-24 83.3 0.1 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92276.1 - 3.6e-06 27.0 1.5 3.6e-06 27.0 1.5 2.5 2 1 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 KRH92276.1 - 0.0059 16.1 3.1 0.014 14.9 0.1 2.7 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) BMFP PF04380.13 KRH92276.1 - 0.19 12.2 0.1 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Membrane fusogenic activity TP6A_N PF04406.14 KRH92277.1 - 6.6e-12 45.2 0.2 1.8e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2220 PF09983.9 KRH92277.1 - 5e-05 22.7 0.1 7.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) gag-asp_proteas PF13975.6 KRH92278.1 - 2.6e-07 31.1 0.0 4.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92278.1 - 5.6e-07 29.4 0.4 9.4e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH92278.1 - 8.1e-06 26.4 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH92278.1 - 0.00045 20.5 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH92278.1 - 0.00094 18.8 0.3 0.00094 18.8 0.3 1.7 1 1 0 2 2 2 1 Ty3 transposon peptidase rve PF00665.26 KRH92279.1 - 4e-24 85.1 0.0 8.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92279.1 - 3.1e-12 46.4 0.3 7.2e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain Poxvirus_B22R_N PF13169.6 KRH92279.1 - 0.0051 17.3 0.2 0.023 15.2 0.2 2.1 1 0 0 1 1 1 1 Poxvirus B22R protein N-terminal MLVIN_C PF18697.1 KRH92279.1 - 0.0093 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_Tnp_IS1595 PF12762.7 KRH92279.1 - 0.016 15.2 1.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 0 ISXO2-like transposase domain PLATZ PF04640.14 KRH92279.1 - 0.35 11.5 2.6 15 6.3 0.4 2.4 2 0 0 2 2 2 0 PLATZ transcription factor WD40 PF00400.32 KRH92280.1 - 2e-07 31.5 2.3 0.0056 17.5 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Tyr_Deacylase PF02580.16 KRH92281.1 - 5.8e-11 43.1 0.0 6.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PGK PF00162.19 KRH92282.1 - 7.2e-22 77.9 0.0 7.9e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Glyco_hydro_32C PF08244.12 KRH92282.1 - 0.049 13.6 0.2 0.075 13.0 0.2 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Flavi_NS5 PF00972.20 KRH92283.1 - 0.071 11.2 0.0 0.092 10.9 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase PRK PF00485.18 KRH92284.1 - 1.7e-14 54.0 0.3 3.5e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KRH92284.1 - 3.1e-05 24.2 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KRH92284.1 - 0.00046 20.1 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein dNK PF01712.19 KRH92284.1 - 0.0019 18.1 0.7 0.0068 16.3 0.7 2.0 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_24 PF13479.6 KRH92284.1 - 0.0043 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KRH92284.1 - 0.0051 17.1 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRH92284.1 - 0.0059 17.1 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH92284.1 - 0.0087 16.5 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KRH92284.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Nod1 PF17114.5 KRH92284.1 - 0.022 14.9 0.2 0.042 14.0 0.2 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 CbiA PF01656.23 KRH92284.1 - 0.038 14.0 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KRH92284.1 - 0.056 13.8 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 KRH92284.1 - 0.058 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 KRH92284.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KRH92284.1 - 0.093 12.8 0.0 0.32 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KRH92284.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 KRH92284.1 - 0.16 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ClpS PF02617.17 KRH92285.1 - 0.036 13.8 0.0 0.046 13.5 0.0 1.3 1 1 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS ATP-cone PF03477.16 KRH92286.1 - 0.078 13.6 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP cone domain gag-asp_proteas PF13975.6 KRH92287.1 - 1.1e-06 29.1 0.1 2.1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92287.1 - 2.4e-05 24.9 0.1 5.3e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH92287.1 - 6.3e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 KRH92287.1 - 0.00049 20.1 2.5 0.00087 19.3 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 KRH92287.1 - 0.00055 20.2 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH92287.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KRH92287.1 - 0.0043 16.8 0.1 0.0071 16.1 0.1 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A2B PF12384.8 KRH92287.1 - 0.0088 15.6 0.2 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Ty3 transposon peptidase Peptidase_A2E PF12382.8 KRH92287.1 - 0.053 13.5 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase zf-C2H2_10 PF16588.5 KRH92287.1 - 0.21 11.3 2.9 0.4 10.4 2.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KRH92287.1 - 0.9 9.4 2.8 1.4 8.8 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle ATP-cone PF03477.16 KRH92288.1 - 0.011 16.3 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 0 ATP cone domain SopA PF13981.6 KRH92289.1 - 0.015 15.8 2.9 0.021 15.2 1.6 2.0 1 1 1 2 2 2 0 SopA-like central domain PWI PF01480.17 KRH92289.1 - 0.023 15.0 0.2 0.098 13.0 0.2 2.1 1 0 0 1 1 1 0 PWI domain YolD PF08863.10 KRH92289.1 - 3.3 7.8 8.6 0.28 11.3 0.2 3.0 3 0 0 3 3 3 0 YolD-like protein TFIIF_alpha PF05793.12 KRH92292.1 - 0.00024 19.8 24.5 0.00024 19.8 24.5 2.9 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KRH92292.1 - 2.4 8.6 7.2 0.75 10.2 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gar1 PF04410.14 KRH92293.1 - 0.0026 17.6 0.4 0.0037 17.0 0.4 1.3 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Sulfate_transp PF00916.20 KRH92295.1 - 6e-06 25.3 1.4 8.8e-06 24.7 1.4 1.2 1 0 0 1 1 1 1 Sulfate permease family CarbpepA_inh PF02977.15 KRH92296.1 - 0.12 12.2 2.1 0.21 11.4 2.1 1.5 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zinc_ribbon_10 PF10058.9 KRH92297.1 - 1.7e-08 34.0 1.0 3e-08 33.3 1.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TctA PF01970.16 KRH92297.1 - 0.017 13.8 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Pex24p PF06398.11 KRH92297.1 - 0.034 13.1 3.6 0.057 12.4 3.6 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Gly_radical PF01228.21 KRH92297.1 - 0.12 12.9 2.1 0.26 11.8 1.0 1.9 1 1 1 2 2 2 0 Glycine radical Ycf70 PF17382.2 KRH92297.1 - 4.4 7.8 6.5 0.49 10.8 0.5 2.5 3 1 1 4 4 4 0 Uncharacterized Ycf70-like CAF1C_H4-bd PF12265.8 KRH92298.1 - 1e-25 89.8 0.4 5.8e-25 87.3 0.3 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KRH92298.1 - 3.4e-18 65.7 1.9 0.00069 20.4 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KRH92298.1 - 0.0053 15.8 0.1 0.074 12.0 0.0 2.5 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_2 PF04059.12 KRH92299.1 - 1.6e-34 118.0 4.9 1.6e-34 118.0 4.9 2.2 3 0 0 3 3 3 1 RNA recognition motif 2 NID PF07292.13 KRH92299.1 - 2 9.1 5.7 7.4 7.3 0.1 3.2 2 1 1 3 3 3 0 Nmi/IFP 35 domain (NID) E2F_TDP PF02319.20 KRH92301.1 - 4e-10 39.6 2.0 4e-10 39.6 2.0 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 KRH92301.1 - 2.8e-08 33.8 6.3 2.8e-08 33.8 6.3 1.8 1 1 0 1 1 1 1 Transcription factor DP DUF4452 PF14618.6 KRH92301.1 - 0.015 15.2 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) TrmB PF01978.19 KRH92301.1 - 0.015 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Myb_DNA-binding PF00249.31 KRH92302.1 - 2e-24 85.5 7.7 3.1e-15 56.1 0.4 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRH92302.1 - 6.1e-19 68.0 10.3 7.1e-12 45.4 1.5 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain HC2 PF07382.11 KRH92302.1 - 0.0094 16.0 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Spore_III_AB PF09548.10 KRH92302.1 - 0.18 11.9 3.9 0.29 11.2 0.1 2.5 1 1 2 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) FRB_dom PF08771.11 KRH92302.1 - 0.25 11.8 3.9 4.2 7.8 0.3 2.5 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain RT_RNaseH PF17917.1 KRH92303.1 - 3.7e-22 78.6 0.0 5.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92303.1 - 7.4e-17 61.2 0.0 1.2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA_anti-codon PF01336.25 KRH92304.1 - 6.2e-13 48.5 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KRH92304.1 - 0.026 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain rve PF00665.26 KRH92306.1 - 2.6e-20 72.8 0.0 4.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92306.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92306.1 - 0.001 19.3 0.5 0.0017 18.6 0.5 1.3 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.6 KRH92306.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF5446 PF17522.2 KRH92307.1 - 0.042 14.0 0.2 0.049 13.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Mre11_DNA_bind PF04152.14 KRH92308.1 - 3.1e-17 63.4 6.4 1.5e-15 57.9 6.4 3.0 1 1 0 1 1 1 1 Mre11 DNA-binding presumed domain Dpoe2NT PF12213.8 KRH92308.1 - 0.081 13.2 3.4 1.9 8.9 1.1 2.6 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal HECT_2 PF09814.9 KRH92309.1 - 0.00062 18.7 4.3 0.0015 17.5 4.2 1.6 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding KMP11 PF03037.16 KRH92309.1 - 0.28 12.0 5.7 1.1 10.1 5.6 2.1 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 HAD_2 PF13419.6 KRH92310.1 - 5.8e-05 23.2 6.0 0.00029 21.0 2.2 2.8 2 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KRH92310.1 - 0.00012 21.9 4.6 0.014 15.3 0.3 2.9 1 1 1 2 2 2 2 Acid Phosphatase Hydrolase PF00702.26 KRH92310.1 - 0.0013 19.1 0.0 0.02 15.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KRH92310.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like DNTTIP1_dimer PF18192.1 KRH92310.1 - 0.43 11.0 4.3 3.7 8.0 0.5 3.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain DUF3983 PF13137.6 KRH92313.1 - 0.65 9.9 5.7 17 5.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3983) DUF3236 PF11576.8 KRH92314.1 - 0.031 14.0 4.1 0.047 13.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) PRA1 PF03208.19 KRH92315.1 - 7.9e-17 61.2 7.5 9.5e-17 61.0 7.5 1.0 1 0 0 1 1 1 1 PRA1 family protein TMPIT PF07851.13 KRH92315.1 - 0.0019 17.5 8.1 0.0026 17.1 8.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein Fucokinase PF07959.12 KRH92317.1 - 0.029 13.3 1.0 0.042 12.8 1.0 1.2 1 0 0 1 1 1 0 L-fucokinase Ndc80_HEC PF03801.13 KRH92318.1 - 9e-17 61.1 2.6 4.1e-16 59.0 2.6 2.0 1 1 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KRH92318.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF3965 PF13112.6 KRH92319.1 - 0.021 14.0 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) DDE_Tnp_IS1595 PF12762.7 KRH92320.1 - 2.9e-18 66.3 0.2 3.7e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF4929 PF16283.5 KRH92320.1 - 0.16 10.9 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) zf-MYST PF17772.1 KRH92320.1 - 0.51 10.0 4.1 7.1 6.3 0.2 2.3 1 1 1 2 2 2 0 MYST family zinc finger domain ANAPC3 PF12895.7 KRH92321.1 - 0.022 15.0 0.5 0.064 13.5 0.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Presenilin PF01080.17 KRH92321.1 - 0.044 12.6 1.9 0.057 12.2 1.9 1.1 1 0 0 1 1 1 0 Presenilin TPR_19 PF14559.6 KRH92321.1 - 0.059 13.9 0.4 0.34 11.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KRH92321.1 - 0.077 13.2 2.5 1 9.6 0.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4820 PF16091.5 KRH92321.1 - 1.4 8.3 4.9 2.2 7.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) rve PF00665.26 KRH92323.1 - 0.00028 21.1 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92323.1 - 0.0082 15.9 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 KRH92324.1 - 5.1e-22 77.8 0.0 5.6e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92324.1 - 2.9e-12 46.8 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Septin PF00735.18 KRH92325.1 - 3e-64 217.0 0.4 3.6e-64 216.8 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KRH92325.1 - 4e-06 26.9 0.3 8.8e-06 25.8 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRH92325.1 - 9e-06 25.7 1.4 0.002 18.0 0.2 2.5 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KRH92325.1 - 3.7e-05 23.2 0.5 0.00011 21.7 0.1 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 KRH92325.1 - 0.00033 20.7 2.2 0.19 11.8 0.3 3.1 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KRH92325.1 - 0.00042 19.9 0.4 0.13 11.8 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF520 PF04461.13 KRH92325.1 - 0.0022 18.2 0.3 0.0041 17.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF520) FeoB_N PF02421.18 KRH92325.1 - 0.0047 16.5 0.4 0.047 13.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Pox_A32 PF04665.12 KRH92325.1 - 0.0097 15.4 0.4 0.025 14.1 0.1 1.8 2 0 0 2 2 2 1 Poxvirus A32 protein Ras PF00071.22 KRH92325.1 - 0.02 14.5 1.0 0.048 13.2 0.1 1.9 2 0 0 2 2 2 0 Ras family AAA_7 PF12775.7 KRH92325.1 - 0.026 14.0 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KRH92325.1 - 0.027 14.7 0.3 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KRH92325.1 - 0.033 13.6 4.8 0.3 10.4 3.2 2.7 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KRH92325.1 - 0.034 14.2 0.2 0.29 11.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 KRH92325.1 - 0.041 13.3 0.6 0.75 9.2 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KRH92325.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KRH92325.1 - 0.058 13.0 0.2 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KRH92325.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KRH92325.1 - 0.076 12.4 0.2 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Formyl_trans_N PF00551.19 KRH92325.1 - 0.085 12.6 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Formyl transferase AAA_33 PF13671.6 KRH92325.1 - 0.087 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KRH92325.1 - 0.095 12.4 2.1 0.13 11.9 2.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KRH92325.1 - 0.12 12.1 0.2 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KRH92325.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Far-17a_AIG1 PF04750.14 KRH92326.1 - 1.4e-05 24.5 2.4 1.6e-05 24.3 2.4 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF5413 PF17434.2 KRH92326.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5413) Myb_DNA-binding PF00249.31 KRH92327.1 - 2.8e-24 85.0 8.2 3.1e-15 56.1 0.4 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRH92327.1 - 6.6e-19 67.9 10.3 7.3e-12 45.4 1.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain HC2 PF07382.11 KRH92327.1 - 0.018 15.1 1.1 0.025 14.6 1.1 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Spore_III_AB PF09548.10 KRH92327.1 - 0.057 13.5 2.8 0.3 11.2 0.1 2.6 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) FRB_dom PF08771.11 KRH92327.1 - 0.88 10.0 4.9 4.4 7.8 0.3 2.6 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Ribosomal_S7e PF01251.18 KRH92328.1 - 9e-10 38.6 3.5 2.4e-08 34.0 3.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S7e UQ_con PF00179.26 KRH92330.1 - 2.6e-37 127.6 0.3 2.9e-37 127.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRH92330.1 - 0.019 14.7 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KRH92330.1 - 0.02 15.2 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain LSM PF01423.22 KRH92331.1 - 1.4e-08 34.3 2.2 9.3e-08 31.7 2.2 1.9 1 1 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KRH92331.1 - 0.02 15.0 0.8 0.021 14.9 0.8 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain 14-3-3 PF00244.20 KRH92332.1 - 2.1e-73 246.5 5.8 2.5e-73 246.3 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4800 PF16057.5 KRH92332.1 - 0.0041 16.4 0.0 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) HBM PF16591.5 KRH92332.1 - 0.048 13.1 0.2 1 8.7 0.0 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain Nup35_RRM PF05172.13 KRH92336.1 - 0.0068 16.3 1.8 0.33 10.9 1.8 2.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ras PF00071.22 KRH92337.1 - 1.7e-42 144.7 0.2 2.2e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH92337.1 - 6.4e-29 100.6 0.2 1.2e-28 99.8 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH92337.1 - 3.8e-18 65.5 0.1 4.8e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KRH92337.1 - 6.7e-08 32.2 0.0 8.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KRH92337.1 - 5e-07 29.3 0.1 6.3e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KRH92337.1 - 0.0009 18.8 2.3 0.0018 17.8 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KRH92337.1 - 0.00092 18.5 4.3 0.14 11.3 4.3 2.9 1 1 0 1 1 1 1 G-protein alpha subunit Pox_A32 PF04665.12 KRH92337.1 - 0.0023 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein RsgA_GTPase PF03193.16 KRH92337.1 - 0.0066 16.4 0.2 1.7 8.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KRH92337.1 - 0.024 14.4 1.1 0.14 11.9 1.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KRH92337.1 - 0.024 14.9 0.1 0.069 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KRH92337.1 - 0.027 14.2 2.5 0.55 10.0 0.1 2.6 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein BspA_v PF18220.1 KRH92337.1 - 0.031 14.4 1.2 0.048 13.8 0.1 1.9 2 1 0 2 2 2 0 Adhesin BspA variable domain AAA_16 PF13191.6 KRH92337.1 - 0.041 14.3 0.0 0.053 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KRH92337.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 KRH92337.1 - 0.09 11.9 0.2 0.13 11.4 0.2 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 KRH92337.1 - 0.11 12.2 0.8 0.32 10.7 0.6 1.8 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KRH92337.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 KRH92337.1 - 0.17 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain GCS PF03074.16 KRH92338.1 - 2.3e-07 30.5 0.0 5.8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Glutamate-cysteine ligase CNH PF00780.22 KRH92339.1 - 2.9e-13 50.1 0.9 1.1e-07 31.8 0.1 2.3 2 0 0 2 2 2 2 CNH domain Afi1 PF07792.12 KRH92339.1 - 0.038 14.5 7.5 0.071 13.6 7.5 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sec62 PF03839.16 KRH92339.1 - 0.064 12.8 1.0 0.11 12.0 1.0 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RPA43_OB PF17875.1 KRH92339.1 - 0.075 13.7 0.3 0.13 12.9 0.3 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CLN3 PF02487.17 KRH92339.1 - 0.78 8.7 5.5 0.059 12.4 0.6 1.5 2 0 0 2 2 2 0 CLN3 protein zf-MYST PF17772.1 KRH92341.1 - 0.025 14.2 2.5 2.2 8.0 0.1 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain DUF4929 PF16283.5 KRH92341.1 - 0.032 13.2 0.1 0.032 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) Pho88 PF10032.9 KRH92342.1 - 8e-28 96.9 5.8 8e-28 96.9 5.8 1.4 1 1 0 1 1 1 1 Phosphate transport (Pho88) DUF4834 PF16118.5 KRH92342.1 - 0.0066 17.4 8.2 0.23 12.5 2.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) SNase PF00565.17 KRH92344.1 - 2.5e-17 63.3 0.0 1.5e-15 57.6 0.0 2.2 1 1 0 1 1 1 1 Staphylococcal nuclease homologue TraP PF07296.11 KRH92344.1 - 0.043 13.0 0.0 0.043 13.0 0.0 1.8 3 0 0 3 3 3 0 TraP protein VirDNA-topo-I_N PF09266.10 KRH92344.1 - 0.1 12.7 0.5 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal YMF19 PF02326.15 KRH92344.1 - 6.2 7.7 7.4 1.5 9.6 1.8 2.5 3 0 0 3 3 3 0 Plant ATP synthase F0 Ribosomal_S11 PF00411.19 KRH92345.1 - 3.6e-33 114.2 0.7 4.7e-33 113.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Glyco_trans_4_2 PF13477.6 KRH92345.1 - 0.087 12.9 0.1 0.23 11.5 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like Pilus_CpaD PF09476.10 KRH92345.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) CcdB PF01845.17 KRH92346.1 - 0.0062 16.8 0.2 0.045 14.0 0.1 1.9 1 1 1 2 2 2 1 CcdB protein DUF4116 PF13475.6 KRH92346.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) DDE_Tnp_IS1595 PF12762.7 KRH92347.1 - 9.2e-19 68.0 0.1 4.4e-18 65.7 0.1 2.0 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_3 PF13358.6 KRH92347.1 - 6.1e-08 32.5 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.6 KRH92347.1 - 1.5e-05 25.2 0.4 0.0001 22.6 0.1 2.3 2 0 0 2 2 2 1 DDE domain zf-BED PF02892.15 KRH92347.1 - 0.036 14.1 3.7 5.7 7.1 0.1 3.1 3 0 0 3 3 3 0 BED zinc finger DDE_Tnp_IS1595 PF12762.7 KRH92348.1 - 1.9e-19 70.2 0.1 3.4e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH92348.1 - 4e-06 26.5 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family AlcCBM31 PF11606.8 KRH92348.1 - 0.03 14.5 0.2 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein ATP-grasp_2 PF08442.10 KRH92348.1 - 0.093 12.3 0.8 4.3 6.9 0.0 2.6 3 0 0 3 3 3 0 ATP-grasp domain PH PF00169.29 KRH92349.1 - 1.1e-05 25.9 1.8 3.6e-05 24.2 1.8 1.9 1 0 0 1 1 1 1 PH domain CHIPS PF11434.8 KRH92349.1 - 8.8 6.2 8.9 3.2 7.7 2.5 3.1 3 1 0 3 3 3 0 Chemotaxis-inhibiting protein CHIPS zf-C2H2 PF00096.26 KRH92351.1 - 1.1e-10 41.4 14.8 3.3e-06 27.3 2.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRH92351.1 - 8.3e-09 35.5 11.6 3.6e-08 33.5 1.2 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KRH92351.1 - 2.4e-06 27.4 1.6 2.4e-06 27.4 1.6 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KRH92351.1 - 1e-05 25.9 14.0 9.7e-05 22.9 1.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Zap1_zf2 PF18217.1 KRH92351.1 - 0.00015 21.6 6.4 0.00015 21.6 6.4 3.1 2 1 0 2 2 2 1 Zap1 zinc finger 2 FOXP-CC PF16159.5 KRH92351.1 - 0.001 19.7 13.5 0.025 15.2 0.5 3.7 2 2 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KRH92351.1 - 0.036 14.4 10.4 0.3 11.4 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KRH92351.1 - 0.042 14.2 12.4 0.084 13.2 2.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KRH92351.1 - 0.048 13.4 2.4 0.31 10.8 0.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KRH92351.1 - 0.073 12.8 20.0 0.34 10.7 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 KRH92351.1 - 0.1 12.9 2.6 0.21 11.9 2.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon Integrase_Zn PF02022.19 KRH92352.1 - 0.0084 16.1 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain RT_RNaseH PF17917.1 KRH92353.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH92354.1 - 0.0092 16.2 0.0 0.0092 16.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.12 KRH92354.1 - 0.031 14.0 0.0 0.031 14.0 0.0 1.0 1 0 0 1 1 1 0 Putative peptidase (DUF1758) MOZ_SAS PF01853.18 KRH92355.1 - 3.4e-40 137.6 0.1 2.6e-35 121.7 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family Acetyltransf_7 PF13508.7 KRH92355.1 - 0.0027 18.1 0.0 0.0066 16.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RRM_7 PF16367.5 KRH92355.1 - 0.015 15.4 0.0 0.052 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Hydin_ADK PF17213.3 KRH92355.1 - 1.9 8.7 4.9 0.34 11.2 1.3 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Ufd2P_core PF10408.9 KRH92357.1 - 5.3e-13 48.5 2.1 5.3e-13 48.5 2.1 1.6 2 0 0 2 2 2 1 Ubiquitin elongating factor core Latarcin PF10279.9 KRH92357.1 - 0.01 16.2 0.2 0.023 15.1 0.2 1.7 1 1 0 1 1 1 0 Latarcin precursor rve PF00665.26 KRH92358.1 - 3.8e-14 52.9 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92358.1 - 9.7e-13 48.0 0.3 2.5e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 KRH92358.1 - 0.0015 18.4 0.9 0.0038 17.0 0.2 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-H2C2 PF09337.10 KRH92358.1 - 0.0028 17.8 0.0 0.0071 16.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger DDE_Tnp_IS240 PF13610.6 KRH92358.1 - 0.0055 16.9 0.2 0.0095 16.2 0.2 1.3 1 0 0 1 1 1 1 DDE domain Na_H_Exchanger PF00999.21 KRH92359.1 - 8.4e-32 110.4 15.1 1.1e-31 110.0 15.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family rve PF00665.26 KRH92360.1 - 1.2e-21 77.1 0.0 1.9e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92360.1 - 0.00043 20.0 0.0 0.00099 18.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92360.1 - 0.021 14.9 1.9 0.04 14.0 1.9 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain EamA PF00892.20 KRH92361.1 - 0.0021 18.2 10.3 0.0021 18.2 10.3 3.1 2 1 1 3 3 3 1 EamA-like transporter family MerC PF03203.14 KRH92361.1 - 0.068 13.6 4.6 0.49 10.9 0.6 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein Rhomboid PF01694.22 KRH92361.1 - 0.49 10.4 8.6 0.04 13.9 1.2 2.6 1 1 0 2 2 2 0 Rhomboid family Vma12 PF11712.8 KRH92361.1 - 2 8.5 6.2 4.7 7.3 0.8 2.7 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1819 PF08849.11 KRH92363.1 - 0.0011 18.8 3.2 0.0021 17.9 2.8 1.6 1 1 0 1 1 1 1 Putative inner membrane protein (DUF1819) Spot_14 PF07084.12 KRH92363.1 - 0.016 15.4 0.3 0.037 14.2 0.3 1.6 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 GCR1_C PF12550.8 KRH92363.1 - 0.039 14.3 1.8 0.098 13.0 1.8 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes DDE_Tnp_IS1595 PF12762.7 KRH92365.1 - 2.3e-17 63.4 0.1 3.2e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Aa_trans PF01490.18 KRH92366.1 - 5.6e-25 87.9 49.7 7.5e-23 80.9 49.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Transposase_1 PF01359.18 KRH92366.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Transposase (partial DDE domain) HTH_Tnp_Tc3_2 PF01498.18 KRH92370.1 - 5.3e-12 45.8 0.4 5.3e-12 45.8 0.4 1.9 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.15 KRH92370.1 - 3.6e-05 23.7 0.5 0.0082 16.2 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KRH92370.1 - 0.00015 22.3 0.1 0.004 17.7 0.0 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KRH92370.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DUF4760 PF15956.5 KRH92370.1 - 0.034 14.3 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) HTH_21 PF13276.6 KRH92370.1 - 0.059 13.5 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 HTH-like domain HTH_38 PF13936.6 KRH92370.1 - 0.094 12.5 1.8 0.15 11.9 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.22 KRH92370.1 - 0.11 12.6 0.1 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_5 PF01022.20 KRH92370.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KRH92370.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Pkinase PF00069.25 KRH92372.1 - 5.8e-45 153.7 5.5 7.5e-44 150.1 5.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92372.1 - 4.6e-25 88.4 0.8 7.1e-24 84.5 0.8 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRH92372.1 - 1.4e-05 24.1 0.3 2e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KRH92372.1 - 0.0063 15.9 0.1 0.0063 15.9 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KRH92372.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RWD PF05773.22 KRH92373.1 - 6.8e-06 26.4 0.7 0.0025 18.1 0.1 2.5 1 1 1 2 2 2 2 RWD domain Inhibitor_G39P PF11417.8 KRH92373.1 - 0.016 15.7 0.9 0.031 14.8 0.2 1.8 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P DHHC PF01529.20 KRH92374.1 - 2.5e-21 76.2 6.9 2.5e-21 76.2 6.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase AbiGi PF10899.8 KRH92374.1 - 0.068 13.0 2.9 1.1 9.1 2.9 2.1 1 1 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin IGFBP PF00219.18 KRH92374.1 - 0.42 11.3 6.7 0.75 10.5 6.7 1.3 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Tfb2_C PF18307.1 KRH92375.1 - 0.14 12.6 0.1 0.42 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain rve PF00665.26 KRH92376.1 - 8.2e-19 67.9 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92376.1 - 6e-16 58.3 0.4 6.9e-15 54.9 0.1 2.6 1 1 1 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH92376.1 - 1.7e-06 28.3 3.9 3.4e-06 27.3 0.5 3.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 KRH92376.1 - 0.013 15.2 0.1 0.23 11.2 0.0 2.7 2 0 0 2 2 2 0 Integrase core domain L27_1 PF09058.10 KRH92376.1 - 0.021 14.8 1.1 21 5.2 0.0 3.9 4 0 0 4 4 4 0 L27_1 zf-H2C2 PF09337.10 KRH92376.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 H2C2 zinc finger gag_pre-integrs PF13976.6 KRH92376.1 - 0.054 13.4 0.3 0.17 11.8 0.3 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain PIN_5 PF08745.11 KRH92376.1 - 0.28 10.6 4.2 5.4 6.4 0.6 3.1 3 0 0 3 3 3 0 PINc domain ribonuclease P4Ha_N PF08336.11 KRH92376.1 - 4.1 7.4 8.5 0.27 11.3 0.9 2.6 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RhoGAP PF00620.27 KRH92377.1 - 1.7e-18 66.9 3.1 2.9e-18 66.2 2.8 1.5 2 0 0 2 2 2 1 RhoGAP domain POTRA_2 PF08479.11 KRH92377.1 - 0.068 13.0 0.2 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, ShlB-type DHH PF01368.20 KRH92378.1 - 2.4e-11 43.7 0.2 4.2e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 KRH92378.1 - 5.8e-07 29.8 0.1 1.1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain RVP_2 PF08284.11 KRH92379.1 - 5.5e-15 55.3 0.1 8.8e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH92379.1 - 1.8e-08 34.9 0.1 3.2e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH92379.1 - 2.9e-08 34.1 0.0 5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.12 KRH92379.1 - 0.0044 16.8 3.5 0.11 12.2 0.0 2.5 2 1 0 3 3 3 2 Putative peptidase (DUF1758) Peptidase_A2B PF12384.8 KRH92379.1 - 0.0056 16.3 1.5 0.0063 16.1 0.1 1.8 2 0 0 2 2 2 1 Ty3 transposon peptidase Asp_protease PF09668.10 KRH92379.1 - 0.038 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 KRH92380.1 - 1.9e-14 53.5 0.7 2.6e-14 53.0 0.7 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92380.1 - 1.1e-05 25.6 0.2 1.8e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger gag_pre-integrs PF13976.6 KRH92380.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain NAD_binding_1 PF00175.21 KRH92382.1 - 2.2e-05 25.0 0.3 0.018 15.7 0.0 2.6 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain Prenyltransf PF01255.19 KRH92384.1 - 8.4e-26 90.9 3.6 7.7e-12 45.2 0.3 3.1 2 1 1 3 3 3 2 Putative undecaprenyl diphosphate synthase Peptidase_C97 PF05903.14 KRH92384.1 - 0.052 13.4 0.1 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 PPPDE putative peptidase domain rve PF00665.26 KRH92385.1 - 8.3e-17 61.5 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92385.1 - 1.1e-08 35.0 0.1 2.5e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH92385.1 - 0.0013 19.0 0.1 0.0038 17.5 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 KRH92385.1 - 0.02 14.7 0.0 0.066 13.0 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain gag_pre-integrs PF13976.6 KRH92385.1 - 0.039 13.8 1.8 0.041 13.7 0.3 1.9 2 0 0 2 2 2 0 GAG-pre-integrase domain Mo-nitro_C PF06967.11 KRH92385.1 - 0.12 12.3 0.1 21 5.2 0.0 2.7 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus DEAD PF00270.29 KRH92386.1 - 8.1e-22 77.8 0.1 1.2e-21 77.3 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH92386.1 - 6.2e-08 32.8 1.6 6.2e-08 32.8 1.6 1.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KRH92386.1 - 0.00042 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KRH92386.1 - 0.0039 17.5 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KRH92386.1 - 0.0049 16.0 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 KRH92386.1 - 0.018 14.5 0.2 0.03 13.8 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 KRH92386.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Flavi_DEAD PF07652.14 KRH92386.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.6 KRH92386.1 - 0.091 12.8 5.9 0.48 10.5 2.8 2.7 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KRH92386.1 - 0.096 12.6 1.0 0.13 12.2 0.2 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KRH92387.1 - 1.1e-29 103.7 2.7 6.6e-29 101.1 2.7 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KRH92387.1 - 4.9e-08 33.1 0.2 0.0023 18.0 0.0 2.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KRH92387.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KRH92387.1 - 0.051 14.0 1.2 0.22 11.9 0.1 2.2 1 1 1 2 2 2 0 RNA helicase ABC_tran PF00005.27 KRH92387.1 - 0.12 12.9 2.4 0.31 11.6 2.2 2.0 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KRH92387.1 - 0.18 11.3 1.7 17 4.9 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B TFIID-31kDa PF02291.15 KRH92388.1 - 2.6e-28 98.5 0.1 3e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KRH92388.1 - 4.1e-06 26.7 0.1 7.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KRH92388.1 - 6.6e-05 23.2 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KRH92388.1 - 0.00018 21.9 0.5 0.00034 21.0 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KRH92388.1 - 0.00053 20.1 0.1 0.00079 19.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KRH92388.1 - 0.0013 18.9 0.2 0.0024 18.1 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KRH92388.1 - 0.0027 17.8 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF1931 PF09123.11 KRH92388.1 - 0.02 15.0 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) TFIID-18kDa PF02269.16 KRH92388.1 - 0.024 14.7 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIIE_alpha PF02002.17 KRH92390.1 - 5.7e-13 48.6 1.5 5.7e-13 48.6 1.5 2.1 3 0 0 3 3 3 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 KRH92390.1 - 0.01 15.9 0.6 0.024 14.8 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain C1_4 PF07975.12 KRH92390.1 - 0.061 13.6 1.5 9.3 6.6 0.1 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain TFIIE-A_C PF11521.8 KRH92390.1 - 0.49 10.7 8.4 1.4 9.3 8.4 1.8 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha SUB1_ProdP9 PF18213.1 KRH92390.1 - 3.6 7.5 8.3 0.59 10.0 0.7 3.1 3 0 0 3 3 3 0 SUB1 protease Prodomain ProdP9 Focal_AT PF03623.13 KRH92390.1 - 5.3 7.0 10.9 1.4 9.0 0.3 3.1 2 1 1 3 3 3 0 Focal adhesion targeting region rve PF00665.26 KRH92392.1 - 4.8e-23 81.6 0.0 1.2e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92392.1 - 7.3e-15 54.8 0.1 1.4e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92392.1 - 7.9e-06 26.0 0.1 1.7e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 KRH92392.1 - 6.4e-05 23.2 0.0 0.00022 21.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 KRH92392.1 - 0.00093 18.9 0.1 0.0024 17.6 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 KRH92392.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease gag_pre-integrs PF13976.6 KRH92392.1 - 0.015 15.1 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain GARS_N PF02844.15 KRH92392.1 - 0.023 15.5 0.0 0.083 13.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain RVT_3 PF13456.6 KRH92392.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like tRNA-synt_2 PF00152.20 KRH92393.1 - 9.8e-15 54.4 0.0 1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KRH92393.1 - 0.015 14.7 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) rve PF00665.26 KRH92395.1 - 0.00018 21.7 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92395.1 - 0.031 14.4 0.9 0.079 13.1 0.9 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain SHMT PF00464.19 KRH92395.1 - 0.092 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase rve PF00665.26 KRH92396.1 - 8.6e-17 61.4 0.2 1.1e-16 61.1 0.2 1.1 1 0 0 1 1 1 1 Integrase core domain ADH_N PF08240.12 KRH92396.1 - 0.032 14.1 0.6 0.042 13.7 0.6 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2612 PF11041.8 KRH92396.1 - 0.26 11.2 2.0 8.2 6.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2612) rve PF00665.26 KRH92397.1 - 8.6e-05 22.7 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92397.1 - 0.0022 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92398.1 - 3.1e-14 52.8 1.1 4.8e-14 52.2 1.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH92398.1 - 4.4e-11 43.0 0.3 2.2e-10 40.8 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 KRH92398.1 - 1.1e-05 25.6 0.9 2e-05 24.7 0.9 1.4 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 KRH92398.1 - 0.15 12.1 1.3 0.26 11.4 0.0 2.1 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase DUF5401 PF17380.2 KRH92398.1 - 1.9 6.4 9.8 2.2 6.3 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH_2 PF17919.1 KRH92399.1 - 3.5e-10 39.8 0.0 4e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP70 PF00012.20 KRH92400.1 - 1.2e-07 30.4 0.9 1.8e-07 29.7 0.4 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KRH92400.1 - 1.7e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 KRH92400.1 - 0.0029 16.3 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 Actin RNase_T PF00929.24 KRH92401.1 - 2.1e-09 38.1 0.3 2.1e-09 38.1 0.3 1.8 2 0 0 2 2 2 1 Exonuclease YqfQ PF14181.6 KRH92401.1 - 1.5 9.0 6.1 2.3 8.4 6.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein Presenilin PF01080.17 KRH92401.1 - 7.8 5.1 5.7 11 4.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 KRH92402.1 - 1.1e-05 25.6 2.5 1.1e-05 25.6 2.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KRH92402.1 - 1.5e-05 24.6 6.0 1.9e-05 24.3 0.2 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 KRH92402.1 - 3.4e-05 24.0 0.9 3.4e-05 24.0 0.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KRH92402.1 - 0.00011 22.0 2.8 0.00011 22.0 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH92402.1 - 0.00022 21.1 4.7 0.00024 21.0 1.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KRH92402.1 - 0.0016 18.2 5.0 0.0016 18.2 5.0 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRH92402.1 - 0.013 15.6 3.5 0.41 10.7 0.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 KRH92402.1 - 0.039 14.0 1.4 0.082 13.0 0.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KRH92402.1 - 0.56 10.4 5.2 2 8.6 5.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KRH92402.1 - 1.8 8.5 5.7 1.6 8.7 3.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) rve PF00665.26 KRH92404.1 - 1.7e-23 83.0 0.0 3.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92404.1 - 2e-05 24.6 0.2 9.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 KRH92404.1 - 0.00014 21.5 0.1 0.00033 20.4 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KRH92404.1 - 0.00089 19.4 0.2 0.0022 18.2 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SWIB PF02201.18 KRH92405.1 - 1.3e-14 53.8 1.5 1.3e-14 53.8 1.5 2.5 3 0 0 3 3 3 1 SWIB/MDM2 domain SKIP_SNW PF02731.15 KRH92405.1 - 0.036 13.7 1.4 0.12 12.1 1.1 2.0 2 0 0 2 2 2 0 SKIP/SNW domain EB1 PF03271.17 KRH92406.1 - 0.00014 22.0 6.9 0.00014 22.0 6.9 2.3 2 0 0 2 2 2 1 EB1-like C-terminal motif Ricin_B_lectin PF00652.22 KRH92407.1 - 0.092 13.0 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain rve PF00665.26 KRH92408.1 - 5.1e-06 26.7 0.0 6.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92408.1 - 0.028 14.5 0.9 0.069 13.3 0.9 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain SHMT PF00464.19 KRH92408.1 - 0.16 10.6 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase CRM1_repeat_3 PF18787.1 KRH92409.1 - 9.2e-12 44.9 4.1 8.5e-10 38.6 0.3 2.7 2 0 0 2 2 2 2 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 KRH92409.1 - 8.6e-06 25.3 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Serglycin PF04360.12 KRH92409.1 - 0.074 13.0 2.3 0.21 11.5 2.3 1.7 1 0 0 1 1 1 0 Serglycin NOT2_3_5 PF04153.18 KRH92410.1 - 1.1e-28 100.0 13.3 1.1e-28 100.0 13.3 2.2 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Ribosomal_L18_c PF14204.6 KRH92411.1 - 0.78 10.7 9.6 0.095 13.6 5.1 1.7 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Erv26 PF04148.13 KRH92413.1 - 1.9e-16 60.6 20.4 4.9e-14 52.7 20.4 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Bac_export_3 PF01313.19 KRH92413.1 - 0.014 15.3 4.3 0.014 15.3 4.3 2.1 2 2 1 3 3 3 0 Bacterial export proteins, family 3 DnaB PF00772.21 KRH92415.1 - 0.054 13.6 2.0 3.5 7.8 0.1 3.5 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Histone PF00125.24 KRH92416.1 - 1.6e-09 38.2 0.6 2.1e-09 37.8 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KRH92416.1 - 0.0032 17.7 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Apo-CII PF05355.11 KRH92416.1 - 0.0043 17.1 0.2 0.0061 16.7 0.2 1.3 1 0 0 1 1 1 1 Apolipoprotein C-II ACD PF16671.5 KRH92416.1 - 0.0057 15.0 0.1 0.0066 14.8 0.1 1.0 1 0 0 1 1 1 1 Actin cross-linking domain RT_RNaseH_2 PF17919.1 KRH92418.1 - 7.3e-31 106.2 0.0 1.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92418.1 - 3.5e-27 94.8 0.0 6e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KRH92418.1 - 0.00012 21.8 0.1 0.00065 19.5 0.1 2.1 1 1 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 KRH92419.1 - 5.8e-20 71.8 0.7 6.9e-20 71.5 0.7 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4367 PF14285.6 KRH92419.1 - 0.024 15.1 0.0 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) RT_RNaseH_2 PF17919.1 KRH92420.1 - 1.3e-30 105.4 0.0 2.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92420.1 - 4.6e-28 97.6 0.0 9e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92420.1 - 4.7e-21 75.3 0.3 8.8e-21 74.4 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KRH92420.1 - 0.0013 18.5 0.0 0.0046 16.8 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase-like RVT_thumb PF06817.14 KRH92420.1 - 0.0093 15.8 0.3 0.032 14.1 0.3 2.0 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_1 PF00078.27 KRH92421.1 - 9.3e-23 80.9 0.0 1.4e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_II PF05188.17 KRH92421.1 - 0.013 15.7 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 MutS domain II Ferritin PF00210.24 KRH92421.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain PCI PF01399.27 KRH92423.1 - 1.6e-07 31.7 2.4 2.9e-07 30.9 0.7 2.3 2 0 0 2 2 2 1 PCI domain Zip PF02535.22 KRH92424.1 - 9.7e-26 90.8 18.6 3.4e-25 89.0 18.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Hemocyanin_N PF03722.14 KRH92426.1 - 0.0012 19.3 3.7 0.0033 17.9 2.1 2.0 1 1 1 2 2 2 1 Hemocyanin, all-alpha domain 7TMR-HDED PF07697.11 KRH92426.1 - 0.049 13.8 0.3 0.057 13.5 0.3 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Ribosomal_L24e PF01246.20 KRH92428.1 - 1.7e-13 50.6 0.2 3.5e-13 49.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Folate_carrier PF01770.18 KRH92429.1 - 1 8.0 3.0 1.1 8.0 3.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier Ribosomal_L29 PF00831.23 KRH92430.1 - 5e-09 36.0 7.1 1.9e-08 34.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal L29 protein VP40 PF07447.12 KRH92430.1 - 0.012 14.8 0.6 0.014 14.5 0.6 1.2 1 0 0 1 1 1 0 Matrix protein VP40 Phage_Nu1 PF07471.12 KRH92430.1 - 0.028 14.2 0.5 0.034 13.9 0.5 1.1 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF3552 PF12072.8 KRH92431.1 - 0.27 10.6 3.6 0.26 10.7 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Imm6 PF14434.6 KRH92432.1 - 0.36 10.8 9.1 0.27 11.2 1.0 2.9 1 1 2 3 3 3 0 Immunity protein Imm6 PAH PF02671.21 KRH92434.1 - 5.4e-05 23.2 0.6 0.0027 17.8 0.1 2.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF1722 PF08349.11 KRH92434.1 - 0.055 13.8 2.3 0.07 13.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) ABC1 PF03109.16 KRH92434.1 - 0.1 12.8 0.7 0.17 12.1 0.7 1.4 1 0 0 1 1 1 0 ABC1 family RPOL_N PF14700.6 KRH92434.1 - 0.13 11.6 1.6 0.28 10.5 1.6 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF4795 PF16043.5 KRH92434.1 - 0.31 10.6 11.0 0.2 11.2 7.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 KRH92434.1 - 0.39 10.0 2.2 0.49 9.7 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med4 PF10018.9 KRH92434.1 - 2.1 8.0 6.3 0.74 9.5 1.7 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 YtxH PF12732.7 KRH92434.1 - 4.5 7.9 8.9 24 5.5 5.5 2.7 2 1 0 2 2 2 0 YtxH-like protein Cauli_AT PF03233.13 KRH92434.1 - 5.2 7.0 16.4 39 4.1 16.4 2.0 1 1 0 1 1 1 0 Aphid transmission protein CPSase_L_D2 PF02786.17 KRH92435.1 - 4.2e-23 82.0 0.0 8.7e-20 71.1 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 KRH92435.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon BAF1_ABF1 PF04684.13 KRH92436.1 - 0.051 12.6 23.3 0.067 12.2 23.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0242 PF06785.11 KRH92436.1 - 0.31 11.1 12.0 0.69 10.0 12.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Presenilin PF01080.17 KRH92436.1 - 0.49 9.1 6.5 0.51 9.0 6.5 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KRH92436.1 - 0.95 8.2 9.9 1.2 7.9 9.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 KRH92436.1 - 3.9 7.2 8.1 7.3 6.3 8.1 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDE_Tnp_IS1595 PF12762.7 KRH92438.1 - 2.6e-08 34.0 0.0 2.8e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain Fim-adh_lectin PF09222.10 KRH92438.1 - 0.15 11.5 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Peptidase_M24 PF00557.24 KRH92439.1 - 6.1e-23 81.6 0.0 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KRH92439.1 - 2.3e-16 59.6 2.2 4.4e-16 58.7 2.2 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N_2 PF16189.5 KRH92439.1 - 0.16 12.1 2.3 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Glyco_transf_20 PF00982.21 KRH92440.1 - 8.7e-13 47.8 0.0 1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 PMT_4TMC PF16192.5 KRH92442.1 - 1.8e-30 106.1 18.8 1.1e-15 57.8 8.9 2.9 2 1 0 2 2 2 2 C-terminal four TMM region of protein-O-mannosyltransferase Sec3_C_2 PF15278.6 KRH92442.1 - 0.037 14.4 0.3 0.094 13.1 0.3 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit RasGEF_N PF00618.20 KRH92442.1 - 1.6 9.0 5.0 2.3 8.5 0.2 3.4 3 1 0 3 3 3 0 RasGEF N-terminal motif NanE PF04131.14 KRH92444.1 - 0.0054 15.9 0.2 0.0059 15.8 0.2 1.0 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase RTX_C PF08339.10 KRH92444.1 - 0.0054 16.8 3.5 0.0065 16.5 3.5 1.1 1 0 0 1 1 1 1 RTX C-terminal domain ACP_PD PF04336.12 KRH92444.1 - 0.015 15.7 0.2 0.023 15.1 0.2 1.3 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase DUF1512 PF07431.12 KRH92444.1 - 0.034 13.2 2.5 0.039 12.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) RVT_1 PF00078.27 KRH92446.1 - 1.2e-24 87.1 0.4 1.4e-24 86.8 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAP2 PF01569.21 KRH92449.1 - 0.00023 21.0 8.2 0.00023 21.0 8.2 2.1 1 1 2 3 3 3 1 PAP2 superfamily Sigma54_activ_2 PF14532.6 KRH92450.1 - 0.00012 22.2 0.0 1.5 8.9 0.0 5.1 2 1 3 5 5 5 1 Sigma-54 interaction domain Bile_Hydr_Trans PF04775.14 KRH92450.1 - 0.19 11.8 1.1 32 4.6 0.0 3.6 4 0 0 4 4 4 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Glyco_hydro_6 PF01341.17 KRH92450.1 - 0.88 9.2 9.4 11 5.6 0.1 4.9 2 2 3 5 5 5 0 Glycosyl hydrolases family 6 UPAR_LY6 PF00021.21 KRH92450.1 - 6 7.6 13.5 1.4e+02 3.3 2.1 3.4 1 1 1 2 2 2 0 u-PAR/Ly-6 domain Aa_trans PF01490.18 KRH92451.1 - 2.8e-23 82.3 43.4 3.5e-23 82.0 24.2 2.7 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein TMEMspv1-c74-12 PF11044.8 KRH92451.1 - 3.6 7.7 13.4 3.2 7.8 0.2 3.5 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Gp_dh_C PF02800.20 KRH92453.1 - 3.9e-55 185.8 0.4 5.3e-55 185.3 0.4 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KRH92453.1 - 2.1e-21 76.1 0.0 6.1e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KRH92453.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_4 PF13291.6 KRH92453.1 - 0.047 14.3 0.1 0.21 12.2 0.1 2.0 2 0 0 2 2 2 0 ACT domain IBV_3B PF03622.13 KRH92454.1 - 0.019 15.1 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 IBV 3B protein Yip1 PF04893.17 KRH92455.1 - 0.099 12.4 16.8 0.4 10.4 11.6 2.7 2 1 0 2 2 2 0 Yip1 domain Actin PF00022.19 KRH92456.1 - 0.00014 20.6 0.1 0.00032 19.4 0.1 1.7 1 1 0 1 1 1 1 Actin DDE_3 PF13358.6 KRH92459.1 - 9.5e-14 51.4 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH92459.1 - 8.4e-09 35.6 8.8 7.1e-08 32.6 3.1 3.2 3 1 0 3 3 3 1 Transposase HTH_32 PF13565.6 KRH92459.1 - 3e-08 34.1 1.1 3.5e-06 27.5 0.2 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.12 KRH92459.1 - 1.3e-05 25.0 0.6 0.0041 17.0 0.1 2.6 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 KRH92459.1 - 0.00013 21.9 0.4 0.0046 16.9 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 KRH92459.1 - 0.00025 21.1 1.0 0.0099 15.9 0.1 3.2 3 1 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_ECF PF07638.11 KRH92459.1 - 0.0073 16.2 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 KRH92459.1 - 0.013 15.3 0.5 0.013 15.3 0.5 3.0 4 0 0 4 4 3 0 Homeodomain-like domain HTH_6 PF01418.17 KRH92459.1 - 0.018 15.0 0.1 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_22 PF13309.6 KRH92459.1 - 0.03 14.4 1.5 0.65 10.1 0.1 3.0 2 1 1 3 3 2 0 HTH domain HTH_12 PF08461.10 KRH92459.1 - 0.047 13.6 1.5 8.3 6.4 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_21 PF13276.6 KRH92459.1 - 0.049 13.8 0.4 0.27 11.4 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain Put_DNA-bind_N PF06971.13 KRH92459.1 - 0.068 13.2 0.3 0.068 13.2 0.3 2.0 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus HTH_33 PF13592.6 KRH92459.1 - 0.087 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix PAX PF00292.18 KRH92459.1 - 0.088 12.7 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 'Paired box' domain Hist_deacetyl PF00850.19 KRH92460.1 - 2.7e-37 128.9 0.9 2e-36 126.1 0.9 1.8 1 1 0 1 1 1 1 Histone deacetylase domain DUF5491 PF17595.2 KRH92460.1 - 0.034 14.4 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5491) AAA PF00004.29 KRH92461.1 - 1.6e-45 154.8 0.1 4.1e-45 153.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KRH92461.1 - 1.9e-08 34.6 0.0 4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KRH92461.1 - 2e-08 34.3 0.4 1.2e-07 31.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 KRH92461.1 - 1.3e-07 31.5 0.5 8.8e-07 28.8 0.1 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KRH92461.1 - 1.3e-07 32.1 0.5 4.3e-05 24.0 0.0 2.7 2 1 0 3 3 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 KRH92461.1 - 8.3e-07 28.7 0.1 1.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 KRH92461.1 - 1e-05 24.8 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KRH92461.1 - 1.6e-05 24.9 0.7 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 KRH92461.1 - 1.9e-05 24.6 0.1 0.0014 18.5 0.0 2.8 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 KRH92461.1 - 9.8e-05 22.6 0.9 0.0057 16.9 0.9 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KRH92461.1 - 0.00027 20.7 0.0 0.00075 19.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KRH92461.1 - 0.00037 20.3 0.0 0.0014 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KRH92461.1 - 0.00047 20.1 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KRH92461.1 - 0.00075 18.8 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KRH92461.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KRH92461.1 - 0.0015 18.1 0.3 0.0066 16.0 0.1 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KRH92461.1 - 0.0016 18.9 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KRH92461.1 - 0.0024 18.2 0.0 0.0078 16.6 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KRH92461.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KRH92461.1 - 0.0029 17.3 0.3 0.072 12.8 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KRH92461.1 - 0.004 16.6 0.2 0.3 10.5 0.0 2.7 1 1 2 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 KRH92461.1 - 0.0052 16.2 0.2 0.017 14.5 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KRH92461.1 - 0.0052 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KRH92461.1 - 0.0054 16.7 0.2 0.049 13.5 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.6 KRH92461.1 - 0.0066 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KRH92461.1 - 0.016 15.1 0.1 0.064 13.1 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KRH92461.1 - 0.02 15.2 0.2 0.24 11.7 0.1 2.5 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KRH92461.1 - 0.024 14.5 2.7 0.19 11.6 0.1 2.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KRH92461.1 - 0.041 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 KRH92461.1 - 0.042 13.5 0.2 0.28 10.9 0.0 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain Parvo_NS1 PF01057.17 KRH92461.1 - 0.043 12.9 0.3 0.099 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 KRH92461.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 KRH92461.1 - 0.086 12.4 1.0 0.38 10.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KRH92461.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter ATPase PF06745.13 KRH92461.1 - 0.4 10.0 3.1 1.2 8.5 0.0 2.6 2 1 0 3 3 3 0 KaiC rve PF00665.26 KRH92463.1 - 5.4e-18 65.3 0.0 9.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92463.1 - 3.4e-08 33.5 0.4 6.6e-08 32.5 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 KRH92463.1 - 0.00068 19.4 0.7 0.0018 18.1 0.7 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 KRH92463.1 - 0.013 15.2 0.1 0.063 13.1 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain FACT-Spt16_Nlob PF14826.6 KRH92464.1 - 4.1e-14 52.7 1.4 4.1e-14 52.7 1.4 1.8 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KRH92464.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 Collagen PF01391.18 KRH92464.1 - 0.27 11.0 13.0 0.45 10.3 13.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) CNOT1_HEAT PF16418.5 KRH92465.1 - 8.6e-20 71.3 0.3 8.6e-20 71.3 0.3 2.3 2 1 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat rve PF00665.26 KRH92466.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92466.1 - 0.014 15.2 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_23 PF13384.6 KRH92468.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KRH92468.1 - 0.00038 20.1 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 KRH92468.1 - 0.0014 18.1 0.0 0.0038 16.7 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KRH92468.1 - 0.0044 16.9 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 KRH92468.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF722 PF05263.11 KRH92468.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Terminase_5 PF06056.12 KRH92468.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 KRH92468.1 - 0.056 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KRH92468.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_AsnC-type PF13404.6 KRH92468.1 - 0.22 11.4 0.0 0.71 9.7 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AAA PF00004.29 KRH92469.1 - 4.1e-41 140.5 0.0 8.7e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KRH92469.1 - 6.5e-16 58.0 0.1 1.5e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KRH92469.1 - 3.3e-13 49.2 0.1 3.6e-12 45.9 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 KRH92469.1 - 4.2e-05 23.7 0.1 0.00027 21.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KRH92469.1 - 7.5e-05 22.7 0.3 0.00057 19.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KRH92469.1 - 9.3e-05 22.2 0.1 0.00025 20.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KRH92469.1 - 0.00021 21.7 0.1 0.058 13.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KRH92469.1 - 0.00058 20.1 0.8 0.38 11.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 KRH92469.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KRH92469.1 - 0.0016 18.2 0.5 0.21 11.3 0.0 3.1 3 1 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 KRH92469.1 - 0.0074 15.8 0.2 0.044 13.2 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KRH92469.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KRH92469.1 - 0.023 14.1 0.3 0.083 12.3 0.3 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KRH92469.1 - 0.028 14.0 0.3 0.094 12.2 0.1 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KRH92469.1 - 0.082 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KRH92469.1 - 0.12 12.1 1.8 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KRH92469.1 - 0.13 12.7 0.0 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KRH92469.1 - 0.14 11.9 1.4 0.97 9.1 0.4 2.8 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KRH92469.1 - 0.24 10.7 1.4 2.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin gag-asp_proteas PF13975.6 KRH92470.1 - 2.5e-07 31.2 0.0 4.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92470.1 - 6.6e-07 29.9 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH92470.1 - 8.4e-06 26.0 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp PF00026.23 KRH92470.1 - 0.12 11.7 0.1 0.28 10.6 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Asp_protease PF09668.10 KRH92470.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease Helicase_C PF00271.31 KRH92471.1 - 9.6e-12 45.2 0.6 9.6e-12 45.2 0.6 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KRH92471.1 - 1.7e-10 41.4 4.5 3.3e-10 40.5 2.6 2.5 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 KRH92471.1 - 0.051 13.4 0.5 0.051 13.4 0.5 2.0 3 0 0 3 3 3 0 RQC domain Ran_BP1 PF00638.18 KRH92472.1 - 3.6e-05 24.0 1.7 0.0075 16.5 0.4 2.8 2 0 0 2 2 2 2 RanBP1 domain FbpA PF05833.11 KRH92473.1 - 1.6e-07 30.5 9.9 1.6e-07 30.5 9.9 3.7 2 1 2 4 4 4 1 Fibronectin-binding protein A N-terminus (FbpA) ATP-synt_E PF05680.12 KRH92474.1 - 2.4 8.5 7.5 1.4 9.3 4.2 2.1 1 1 0 2 2 2 0 ATP synthase E chain Aa_trans PF01490.18 KRH92475.1 - 7.6e-22 77.6 9.0 9.7e-22 77.2 9.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KRH92475.1 - 4.1e-08 32.7 11.8 5.9e-08 32.2 11.5 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AOX PF01786.17 KRH92476.1 - 1.5e-69 233.9 0.1 1.9e-69 233.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 KRH92476.1 - 0.0098 15.7 0.1 0.033 14.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 ERO1 PF04137.15 KRH92477.1 - 6.4e-19 68.4 14.9 2.9e-11 43.2 1.3 3.8 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RVT_1 PF00078.27 KRH92478.1 - 3.8e-33 114.9 0.2 5.1e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH92479.1 - 1.7e-24 86.1 0.1 2.4e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92479.1 - 2.6e-13 49.9 0.0 5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92479.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H3C2 PF16721.5 KRH92481.1 - 0.042 14.2 0.5 0.052 13.9 0.5 1.0 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding TRCF PF03461.15 KRH92482.1 - 0.019 15.3 2.5 0.045 14.1 2.5 1.6 1 0 0 1 1 1 0 TRCF domain LCIB_C_CA PF18599.1 KRH92482.1 - 0.091 12.0 1.1 0.12 11.6 1.1 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DDE_Tnp_ISAZ013 PF07592.11 KRH92482.1 - 0.13 11.2 4.8 0.19 10.7 4.8 1.3 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF5531 PF17671.1 KRH92482.1 - 0.19 11.6 8.7 0.33 10.8 8.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Tugs PF17840.1 KRH92482.1 - 0.3 11.3 1.7 0.62 10.3 0.2 2.3 2 1 0 2 2 2 0 Tethering Ubl4a to BAGS domain SirA PF10747.9 KRH92482.1 - 0.55 10.6 9.9 0.13 12.6 6.6 1.6 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA Ras PF00071.22 KRH92483.1 - 3.9e-46 156.6 0.0 5.5e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH92483.1 - 5.6e-23 81.4 0.0 8.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH92483.1 - 2.8e-08 33.4 0.0 4.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KRH92483.1 - 0.0074 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KRH92483.1 - 0.14 11.9 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AhpC-TSA PF00578.21 KRH92485.1 - 3.7e-17 62.4 0.1 7e-17 61.5 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KRH92485.1 - 9.2e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Redoxin zf-CCCH_3 PF15663.5 KRH92486.1 - 2e-21 76.2 12.5 2.8e-21 75.8 12.5 1.2 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KRH92486.1 - 0.0081 16.6 19.5 0.035 14.6 4.6 3.7 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger DUF5355 PF17306.2 KRH92487.1 - 0.032 13.3 0.1 0.072 12.1 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5355) Latarcin PF10279.9 KRH92491.1 - 0.24 11.8 2.8 0.28 11.6 2.8 1.1 1 0 0 1 1 1 0 Latarcin precursor Asp_protease_2 PF13650.6 KRH92492.1 - 7.6e-06 26.5 0.0 9.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH92492.1 - 0.005 17.4 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92492.1 - 0.009 15.8 0.0 0.0095 15.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH92492.1 - 0.038 13.5 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase B277 PF17623.2 KRH92493.1 - 0.0055 15.8 0.5 0.0055 15.8 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function UQ_con PF00179.26 KRH92494.1 - 6.3e-48 162.0 0.0 7.2e-48 161.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRH92494.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KRH92494.1 - 0.0011 19.2 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 RWD domain rve PF00665.26 KRH92495.1 - 0.00015 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92495.1 - 0.0026 17.5 0.0 0.0058 16.4 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92496.1 - 3.1e-14 52.8 1.1 4.8e-14 52.2 1.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH92496.1 - 4.4e-11 43.0 0.3 2.2e-10 40.8 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 KRH92496.1 - 1.1e-05 25.6 0.9 2e-05 24.7 0.9 1.4 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 KRH92496.1 - 0.15 12.1 1.3 0.26 11.4 0.0 2.1 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase DUF5401 PF17380.2 KRH92496.1 - 1.9 6.4 9.8 2.2 6.3 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RT_RNaseH_2 PF17919.1 KRH92497.1 - 3.5e-10 39.8 0.0 4e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UCH PF00443.29 KRH92500.1 - 8.1e-05 22.2 10.1 0.026 14.0 10.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH92500.1 - 0.0048 16.5 2.2 0.014 15.0 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF751 PF05421.11 KRH92500.1 - 0.02 15.6 0.6 0.06 14.1 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF751) HSBP1 PF06825.12 KRH92501.1 - 0.47 10.4 4.8 2 8.3 0.2 3.4 4 0 0 4 4 4 0 Heat shock factor binding protein 1 SWIRM-assoc_1 PF16495.5 KRH92501.1 - 0.7 9.9 3.8 0.75 9.8 1.2 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 Pox_D5 PF03288.16 KRH92501.1 - 2 9.0 12.1 0.34 11.4 1.1 3.6 2 1 1 3 3 3 0 Poxvirus D5 protein-like HTH_23 PF13384.6 KRH92502.1 - 0.00034 20.3 0.0 0.00071 19.3 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KRH92502.1 - 0.0039 17.3 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KRH92502.1 - 0.032 13.9 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_32 PF13565.6 KRH92502.1 - 0.034 14.7 0.0 0.064 13.9 0.0 1.4 2 0 0 2 2 2 0 Homeodomain-like domain PAX PF00292.18 KRH92502.1 - 0.061 13.2 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.6 KRH92503.1 - 6.6e-25 87.6 0.0 7.8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-6 PF01912.18 KRH92504.1 - 1.1e-67 227.3 1.7 1.3e-67 227.1 1.7 1.1 1 0 0 1 1 1 1 eIF-6 family RVT_1 PF00078.27 KRH92505.1 - 2.4e-16 60.0 0.2 4.4e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sof1 PF04158.14 KRH92506.1 - 1.4e-08 34.9 8.8 3.6e-08 33.6 8.8 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KRH92506.1 - 4.8e-07 30.4 5.2 0.0012 19.6 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KRH92506.1 - 0.041 13.9 0.0 2 8.5 0.0 2.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KRH92507.1 - 0.00025 21.8 0.8 0.16 12.9 0.2 4.4 5 1 0 5 5 5 1 WD domain, G-beta repeat DUF3387 PF11867.8 KRH92507.1 - 0.08 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ribosomal_L7Ae PF01248.26 KRH92508.1 - 2.5e-19 68.8 1.1 5e-19 67.8 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DDE_Tnp_ISL3 PF01610.17 KRH92508.1 - 0.062 13.0 1.2 0.1 12.3 1.2 1.3 1 0 0 1 1 1 0 Transposase OmdA PF13376.6 KRH92508.1 - 0.086 12.9 0.9 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Complex1_LYR_2 PF13233.6 KRH92508.1 - 0.13 13.0 0.6 0.48 11.2 0.9 1.8 2 0 0 2 2 2 0 Complex1_LYR-like Mg_trans_NIPA PF05653.14 KRH92509.1 - 2.8e-28 98.9 25.3 8.3e-20 71.1 7.0 2.3 2 1 0 2 2 2 2 Magnesium transporter NIPA Nodulin_late PF07127.11 KRH92509.1 - 0.057 13.8 1.0 0.057 13.8 1.0 5.3 4 1 1 5 5 5 0 Late nodulin protein Nudc_N PF14050.6 KRH92511.1 - 0.021 14.8 0.3 0.082 12.9 0.1 2.2 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Orthopox_A36R PF05950.11 KRH92511.1 - 0.14 12.3 9.4 0.04 14.1 5.1 2.1 1 1 0 1 1 1 0 Orthopoxvirus A36R protein Sof1 PF04158.14 KRH92511.1 - 0.67 10.3 9.4 1.5 9.2 9.0 1.8 1 1 0 1 1 1 0 Sof1-like domain EIN3 PF04873.13 KRH92511.1 - 3 7.1 8.4 0.59 9.4 0.3 2.1 1 1 1 2 2 2 0 Ethylene insensitive 3 CBFD_NFYB_HMF PF00808.23 KRH92512.1 - 0.0027 18.0 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRH92512.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 LCIB_C_CA PF18599.1 KRH92512.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases TAFII28 PF04719.14 KRH92512.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region rve PF00665.26 KRH92513.1 - 5.1e-14 52.5 0.0 1.6e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92513.1 - 1.4e-12 47.6 0.2 3.4e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KRH92513.1 - 0.0021 17.8 0.1 0.0048 16.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92514.1 - 7.1e-13 48.5 0.1 1.6e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH92514.1 - 4.6e-12 46.2 0.0 8.4e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92514.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KRH92514.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCCH_6 PF18585.1 KRH92515.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Chs7 PF12271.8 KRH92516.1 - 5.5e-12 45.7 29.2 2e-11 43.8 29.2 1.8 1 1 0 1 1 1 1 Chitin synthase export chaperone Cyclin_N PF00134.23 KRH92517.1 - 9.8e-22 77.1 3.4 1.1e-21 76.9 0.4 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain MscS_TM PF12794.7 KRH92517.1 - 4.5 6.0 4.5 7.7 5.3 4.5 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 D5_N PF08706.11 KRH92518.1 - 0.81 9.9 4.5 0.57 10.4 2.4 1.9 2 1 0 2 2 2 0 D5 N terminal like SSrecog PF03531.14 KRH92518.1 - 1.9 8.5 4.9 3.1 7.8 0.6 2.5 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) mRNA_triPase PF02940.15 KRH92519.1 - 1.7e-23 83.5 4.7 5.6e-13 49.1 1.0 2.0 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain SHS2_Rpb7-N PF03876.17 KRH92520.1 - 0.00017 21.9 0.1 0.0003 21.1 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 KRH92520.1 - 0.0026 18.0 1.6 0.24 11.6 0.3 2.5 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 ApoC-I PF04691.12 KRH92521.1 - 0.13 12.2 2.0 12 5.9 1.5 3.1 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) LRR_RI_capping PF18779.1 KRH92521.1 - 0.7 9.6 6.8 58 3.5 0.0 4.4 5 0 0 5 5 5 0 Capping Ribonuclease inhibitor Leucine Rich Repeat RIBIOP_C PF04950.12 KRH92522.1 - 1.9e-16 60.3 5.3 6.8e-14 52.0 2.4 2.5 2 1 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Pkinase PF00069.25 KRH92523.1 - 2.1e-67 227.3 0.0 2.5e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92523.1 - 7.1e-39 133.6 0.0 1.2e-38 132.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH92523.1 - 9.6e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KRH92523.1 - 0.0005 19.1 0.9 0.012 14.5 0.9 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KRH92523.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KRH92523.1 - 0.0096 15.3 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TBP PF00352.21 KRH92525.1 - 1.3e-66 220.5 1.3 2.9e-32 110.5 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KRH92525.1 - 2e-05 24.6 0.0 0.085 13.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KRH92525.1 - 0.028 14.2 0.1 0.22 11.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) rve PF00665.26 KRH92526.1 - 1.4e-07 31.7 0.0 2.4e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_IS1595 PF12762.7 KRH92526.1 - 0.0019 18.2 0.1 0.0021 18.1 0.1 1.2 1 1 0 1 1 1 1 ISXO2-like transposase domain Glyco_hydro_71 PF03659.14 KRH92526.1 - 0.02 13.7 0.0 0.02 13.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Dus PF01207.17 KRH92527.1 - 1.1e-43 149.5 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ASD2 PF08687.11 KRH92527.1 - 0.11 12.0 0.3 2 7.9 0.1 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 RT_RNaseH_2 PF17919.1 KRH92528.1 - 1e-29 102.5 0.2 4e-29 100.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92528.1 - 4.2e-29 100.9 0.0 8.8e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH92528.1 - 1.6e-16 60.6 0.0 4.7e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 KRH92528.1 - 4.2e-12 46.1 0.1 1.3e-11 44.5 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 KRH92528.1 - 1.7e-05 24.8 1.6 0.00062 19.8 1.5 2.8 2 1 0 2 2 2 1 Integrase zinc binding domain RNase_H PF00075.24 KRH92528.1 - 8e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 RNase H DUF4373 PF14297.6 KRH92528.1 - 0.067 14.0 0.3 0.37 11.6 0.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) TPR_21 PF09976.9 KRH92530.1 - 0.0078 15.9 4.0 0.041 13.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain HRDC PF00570.23 KRH92530.1 - 0.13 12.3 0.1 0.36 10.8 0.1 1.9 1 0 0 1 1 1 0 HRDC domain Pkinase PF00069.25 KRH92531.1 - 2.7e-17 63.0 0.0 4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3660 PF12398.8 KRH92531.1 - 0.067 13.3 1.3 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Receptor serine/threonine kinase RT_RNaseH PF17917.1 KRH92532.1 - 9.6e-20 70.8 0.2 1.9e-19 69.9 0.2 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92532.1 - 1.6e-11 44.1 0.1 3.3e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92533.1 - 7e-19 68.2 0.1 7.9e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aa_trans PF01490.18 KRH92534.1 - 1.1e-35 123.1 11.5 2e-35 122.3 11.5 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2721 PF11026.8 KRH92534.1 - 0.26 11.2 6.3 3 7.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4271 PF14093.6 KRH92534.1 - 2 8.3 30.1 0.044 13.7 8.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) Wzy_C PF04932.15 KRH92534.1 - 2.7 7.6 8.6 39 3.8 0.0 2.6 1 1 0 2 2 2 0 O-Antigen ligase DUF4661 PF15576.6 KRH92534.1 - 9.3 6.1 8.5 14 5.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Rtt106 PF08512.12 KRH92535.1 - 1.2e-15 57.7 10.2 2.3e-14 53.5 0.4 3.4 4 0 0 4 4 4 2 Histone chaperone Rttp106-like SSrecog PF03531.14 KRH92535.1 - 7.6e-08 32.2 0.4 3.2e-07 30.2 0.1 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KRH92535.1 - 1.2e-05 25.6 0.4 0.0002 21.7 0.1 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain KH_10 PF17905.1 KRH92535.1 - 0.19 12.2 3.2 0.42 11.1 0.2 2.9 3 1 0 3 3 3 0 GLD-3 KH domain 5 SRP54 PF00448.22 KRH92536.1 - 9.2e-35 120.1 0.0 1.6e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KRH92536.1 - 4.8e-05 23.9 0.0 4.8e-05 23.9 0.0 2.8 2 1 0 2 2 1 1 ABC transporter AAA_15 PF13175.6 KRH92536.1 - 0.00056 19.7 3.5 0.00056 19.7 3.5 2.4 1 1 1 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KRH92536.1 - 0.022 15.1 0.3 0.088 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KRH92536.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KRH92536.1 - 0.034 13.6 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KRH92536.1 - 0.041 14.0 0.2 0.041 14.0 0.2 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KRH92536.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KRH92536.1 - 0.052 13.9 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KRH92536.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 KRH92536.1 - 0.24 11.7 8.0 0.082 13.1 3.7 2.6 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain AAA_14 PF13173.6 KRH92536.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain Nop PF01798.18 KRH92537.1 - 6.9e-55 186.0 6.2 4e-41 141.0 0.4 3.0 3 0 0 3 3 3 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KRH92537.1 - 0.0005 20.4 1.3 0.0014 19.0 1.3 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain FAM91_C PF14648.6 KRH92537.1 - 0.00075 18.4 0.3 0.00075 18.4 0.3 1.9 2 0 0 2 2 2 1 FAM91 C-terminus Trypan_PARP PF05887.11 KRH92537.1 - 2 8.4 9.5 3.4 7.6 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF5094 PF17015.5 KRH92538.1 - 1.2e-14 54.9 48.5 3.1e-13 50.2 40.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5094) Mitofilin PF09731.9 KRH92538.1 - 0.0029 16.5 22.4 0.0037 16.2 22.4 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Macoilin PF09726.9 KRH92538.1 - 0.05 12.2 21.0 0.061 11.9 21.0 1.0 1 0 0 1 1 1 0 Macoilin family GldM_N PF12081.8 KRH92538.1 - 0.053 13.6 25.2 0.082 13.0 25.2 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Borrelia_P83 PF05262.11 KRH92538.1 - 0.48 8.9 26.4 0.56 8.6 26.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Membralin PF09746.9 KRH92538.1 - 1.6 7.7 13.9 2.4 7.1 13.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein Exonuc_VII_L PF02601.15 KRH92538.1 - 1.7 8.1 14.1 2.4 7.6 14.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mem_trans PF03547.18 KRH92538.1 - 7 4.9 5.2 7.6 4.8 5.2 1.2 1 0 0 1 1 1 0 Membrane transport protein CTP_transf_like PF01467.26 KRH92539.1 - 4.5e-26 91.8 0.1 6.7e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like CagX PF03524.15 KRH92539.1 - 0.04 13.7 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein RT_RNaseH_2 PF17919.1 KRH92541.1 - 5e-13 48.9 0.1 5.7e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92541.1 - 3.1e-09 37.1 0.0 3.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KRH92542.1 - 2.2e-06 28.1 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92542.1 - 1.1e-05 25.9 0.0 2.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH92542.1 - 0.00012 22.4 0.0 0.00035 20.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease PA28_alpha PF02251.18 KRH92542.1 - 0.014 15.4 0.0 0.067 13.3 0.0 2.2 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Retrotrans_gag PF03732.17 KRH92542.1 - 0.015 15.5 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Spuma_A9PTase PF03539.14 KRH92542.1 - 0.036 14.2 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 Spumavirus aspartic protease (A9) Asp_protease PF09668.10 KRH92542.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 KRH92542.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_IS1595 PF12762.7 KRH92543.1 - 1e-22 80.8 0.2 3.7e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH92543.1 - 0.00046 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family zinc_ribbon_15 PF17032.5 KRH92544.1 - 5.8e-08 33.4 26.5 5.8e-08 33.4 26.5 1.9 2 0 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 KRH92544.1 - 0.014 15.4 0.3 0.014 15.4 0.3 3.1 1 1 1 2 2 2 0 Double zinc ribbon Sec8_exocyst PF04048.14 KRH92545.1 - 5.1e-14 52.3 6.5 5.1e-14 52.3 6.5 3.2 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain JAB PF01398.21 KRH92546.1 - 6.3e-30 103.6 0.2 1.5e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KRH92546.1 - 1.9e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KRH92546.1 - 0.03 14.4 0.0 0.069 13.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) C_Hendra PF16821.5 KRH92547.1 - 8.8 6.2 10.9 0.1 12.5 2.3 2.2 3 0 0 3 3 3 0 C protein from hendra and measles viruses PH_11 PF15413.6 KRH92548.1 - 0.015 15.7 0.2 0.052 14.0 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PPI_Ypi1 PF07491.11 KRH92550.1 - 2.6e-10 40.0 0.1 4e-10 39.4 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF2023 PF09633.10 KRH92551.1 - 0.0097 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2023) Codanin-1_C PF15296.6 KRH92553.1 - 0.26 11.4 3.0 0.22 11.6 0.6 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus ATP-synt_ab PF00006.25 KRH92554.1 - 1e-68 231.2 0.0 1.5e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KRH92554.1 - 1.3e-09 38.4 0.9 2.5e-09 37.5 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain rve_3 PF13683.6 KRH92555.1 - 3e-06 26.9 0.2 6.7e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 KRH92555.1 - 0.00012 22.2 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1331 PF07048.11 KRH92556.1 - 5.6 6.7 13.0 4.6 7.0 0.2 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF1331) DUF5111 PF17138.4 KRH92556.1 - 8.7 6.2 6.4 93 2.9 0.3 4.1 2 2 4 6 6 6 0 Domain of unknown function (DUF5111) CPSase_L_D2 PF02786.17 KRH92557.1 - 1.2e-24 87.0 0.2 2.3e-21 76.2 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 KRH92557.1 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Hce2 PF14856.6 KRH92557.1 - 0.63 10.4 9.7 4.1 7.7 1.0 3.7 1 1 2 3 3 3 0 Pathogen effector; putative necrosis-inducing factor SMC_hinge PF06470.13 KRH92558.1 - 4.4e-07 30.2 0.2 4.5e-05 23.7 0.0 3.1 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain DUF3012 PF11216.8 KRH92558.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Creatinase_N PF01321.18 KRH92559.1 - 1.7e-13 51.4 0.0 1.3e-09 38.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Creatinase_N_2 PF16189.5 KRH92559.1 - 2.6e-10 40.6 0.2 2.6e-10 40.6 0.2 2.9 2 2 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Quaking_NLS PF16551.5 KRH92561.1 - 0.1 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal of quaking PTPLA PF04387.14 KRH92562.1 - 4.9e-27 94.7 14.1 1.6e-26 93.0 14.1 1.7 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_1b PF00579.25 KRH92564.1 - 3e-56 190.9 0.1 3.5e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RVP_2 PF08284.11 KRH92565.1 - 0.0038 17.0 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH92565.1 - 0.01 16.5 0.0 0.016 15.9 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Integrase_H2C2 PF17921.1 KRH92567.1 - 2.7e-12 46.6 0.9 4.2e-12 46.0 0.9 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH92567.1 - 4.6e-06 26.7 0.6 9.2e-06 25.8 0.6 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 KRH92567.1 - 0.0041 17.3 0.0 0.0059 16.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.12 KRH92567.1 - 0.053 13.3 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) EamA PF00892.20 KRH92568.1 - 1.6e-05 25.1 30.4 0.0014 18.8 13.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family Phage_holin_2_1 PF04971.12 KRH92568.1 - 0.041 13.9 0.9 0.078 13.0 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S ASFV_L11L PF05293.11 KRH92568.1 - 0.9 9.9 19.9 3.5 8.0 1.8 3.9 2 1 1 3 3 3 0 African swine fever virus (ASFV) L11L protein RT_RNaseH_2 PF17919.1 KRH92569.1 - 0.0018 18.3 0.0 0.0019 18.2 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase LRR_4 PF12799.7 KRH92571.1 - 3.2e-13 49.6 28.3 7.2e-07 29.4 5.4 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KRH92571.1 - 7.2e-13 48.1 18.5 9.1e-08 31.7 5.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KRH92571.1 - 7.5e-06 25.8 13.4 0.14 12.8 0.3 4.8 5 0 0 5 5 5 4 Leucine Rich Repeat DUF4116 PF13475.6 KRH92571.1 - 2.7 7.8 8.9 69 3.3 8.9 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) Porin_3 PF01459.22 KRH92572.1 - 7.5e-07 28.9 0.2 7.7e-06 25.6 0.2 2.3 1 1 0 1 1 1 1 Eukaryotic porin MTS_N PF08468.11 KRH92572.1 - 0.021 14.9 1.0 0.032 14.3 1.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Retrotrans_gag PF03732.17 KRH92576.1 - 0.004 17.4 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-ZPR1 PF03367.13 KRH92577.1 - 1.3e-10 41.3 1.8 4e-06 26.8 1.1 2.5 1 1 0 2 2 2 2 ZPR1 zinc-finger domain Elf1 PF05129.13 KRH92577.1 - 0.013 15.5 4.8 4.1 7.5 0.2 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KRH92577.1 - 0.1 12.6 1.2 0.37 10.8 1.2 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FdhE PF04216.12 KRH92577.1 - 0.12 12.2 0.7 0.37 10.6 0.7 1.7 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation zinc_ribbon_10 PF10058.9 KRH92577.1 - 0.36 10.6 2.3 0.79 9.5 2.3 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein NTP_transf_2 PF01909.23 KRH92578.1 - 1e-08 35.4 0.0 5.7e-08 32.9 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KRH92578.1 - 2.6e-05 24.3 2.4 2.6e-05 24.3 2.4 3.2 2 1 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 KRH92578.1 - 0.0028 17.7 0.2 0.028 14.5 0.0 2.7 2 1 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 KRH92579.1 - 1.2e-54 185.4 0.7 9e-35 120.3 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92579.1 - 5.9e-30 104.4 0.3 3.9e-19 69.0 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4744 PF15918.5 KRH92579.1 - 2.4e-07 31.5 18.7 0.00012 22.8 7.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4744) MSG PF02349.15 KRH92579.1 - 7e-05 22.9 45.9 0.034 14.3 1.4 4.1 2 1 2 4 4 4 3 Major surface glycoprotein Pkinase_fungal PF17667.1 KRH92579.1 - 0.0019 17.1 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KRH92579.1 - 0.0021 17.4 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KRH92579.1 - 0.0029 17.3 0.3 0.23 11.0 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DUF4337 PF14235.6 KRH92579.1 - 0.059 13.5 1.5 0.37 10.9 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) MAD PF05557.13 KRH92579.1 - 0.065 11.6 0.8 0.16 10.3 0.8 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein APH PF01636.23 KRH92579.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KRH92579.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_3 PF01764.25 KRH92580.1 - 7.1e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KRH92580.1 - 6.1e-06 25.7 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KRH92580.1 - 8.5e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KRH92580.1 - 0.0011 18.7 1.3 0.02 14.6 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Cutinase PF01083.22 KRH92580.1 - 0.0014 18.6 0.4 0.0045 17.0 0.4 1.7 1 1 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.7 KRH92580.1 - 0.0034 17.2 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KRH92580.1 - 0.0091 15.6 0.3 0.089 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KRH92580.1 - 0.05 14.2 0.0 0.072 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dicty_spore_N PF04562.12 KRH92580.1 - 0.057 14.1 2.6 0.12 13.1 2.6 1.5 1 0 0 1 1 1 0 Dictyostelium spore coat protein, N terminus Thioesterase PF00975.20 KRH92580.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF4256 PF14066.6 KRH92580.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4256) LIDHydrolase PF10230.9 KRH92580.1 - 0.15 11.6 1.1 0.79 9.2 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase ApoB100_C PF12491.8 KRH92581.1 - 2.6 8.1 7.7 3.4 7.7 0.3 2.6 2 1 1 3 3 3 0 Apolipoprotein B100 C terminal DEAD PF00270.29 KRH92582.1 - 2.4e-26 92.6 0.0 6.9e-25 87.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH92582.1 - 4.6e-05 23.7 0.1 0.00014 22.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TatD_DNase PF01026.21 KRH92583.1 - 6.7e-40 137.1 0.0 8.8e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Nop14 PF04147.12 KRH92583.1 - 0.036 12.3 0.0 0.05 11.8 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family PAH PF02671.21 KRH92583.1 - 0.046 13.9 5.4 0.26 11.5 0.0 3.2 3 0 0 3 3 3 0 Paired amphipathic helix repeat zf-RING_2 PF13639.6 KRH92585.1 - 1.2e-08 35.1 14.2 2.6e-08 34.1 14.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KRH92585.1 - 1.5e-07 31.2 13.5 2.7e-07 30.3 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KRH92585.1 - 1.6e-06 28.3 9.1 4.9e-06 26.7 9.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KRH92585.1 - 2.4e-05 24.0 3.4 8.5e-05 22.2 3.4 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KRH92585.1 - 0.00068 19.5 11.9 0.0012 18.7 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH92585.1 - 0.0083 16.0 15.3 0.018 14.9 15.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH92585.1 - 0.009 16.0 13.5 0.018 15.0 13.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KRH92585.1 - 0.0098 15.9 6.6 0.0098 15.9 6.6 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KRH92585.1 - 0.014 15.0 10.2 0.029 14.0 10.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NVEALA PF14055.6 KRH92585.1 - 0.019 14.9 1.5 0.04 13.9 1.5 1.5 1 0 0 1 1 1 0 NVEALA protein zf-ANAPC11 PF12861.7 KRH92585.1 - 0.19 11.8 9.5 1.5 8.9 9.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KRH92585.1 - 0.25 11.3 12.4 0.49 10.3 12.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KRH92585.1 - 0.95 9.3 5.0 2.6 7.9 5.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tmemb_161AB PF10268.9 KRH92586.1 - 0.0082 14.8 0.0 0.0092 14.7 0.0 1.0 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB RL10P_insert PF17777.1 KRH92587.1 - 3.5e-19 68.5 0.2 3.5e-19 68.5 0.2 1.9 3 0 0 3 3 3 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KRH92587.1 - 8.5e-19 67.6 4.9 8.5e-19 67.6 4.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 CitX PF03802.14 KRH92587.1 - 0.006 16.4 1.2 0.011 15.6 1.2 1.4 1 0 0 1 1 1 1 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF2620 PF10941.8 KRH92587.1 - 0.057 13.6 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DUF760 PF05542.11 KRH92587.1 - 0.64 10.4 2.0 4.7 7.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF760) MqsR_toxin PF15723.5 KRH92588.1 - 0.019 15.3 0.1 0.022 15.1 0.1 1.1 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA DUF3903 PF13043.6 KRH92588.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) Carb_anhydrase PF00194.21 KRH92589.1 - 0.028 14.0 0.3 0.03 13.9 0.3 1.0 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase DUF4375 PF14300.6 KRH92589.1 - 0.072 13.4 2.3 0.077 13.3 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DDE_3 PF13358.6 KRH92591.1 - 0.0062 16.3 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_48 PF17906.1 KRH92592.1 - 0.039 14.1 0.3 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 HTH domain in Mos1 transposase DUF3552 PF12072.8 KRH92593.1 - 0.0002 20.9 8.5 0.00035 20.1 8.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DDE_3 PF13358.6 KRH92594.1 - 4.9e-10 39.3 0.0 5.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2661 PF10860.8 KRH92595.1 - 0.0049 17.0 0.3 0.0049 17.0 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2661) Img2 PF05046.14 KRH92595.1 - 0.033 14.5 0.2 0.074 13.4 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Acylphosphatase PF00708.18 KRH92595.1 - 0.037 14.4 0.1 0.091 13.2 0.1 1.7 1 0 0 1 1 1 0 Acylphosphatase ESSS PF10183.9 KRH92597.1 - 0.63 10.3 0.1 0.63 10.3 0.1 2.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2569 PF10754.9 KRH92597.1 - 7.8 6.9 12.1 0.53 10.7 6.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Metallophos PF00149.28 KRH92600.1 - 2.4e-10 41.3 0.1 9.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KRH92600.1 - 2.8e-10 40.6 0.0 0.00091 19.5 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Lin-8 PF03353.15 KRH92600.1 - 0.045 13.3 0.5 0.074 12.6 0.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RRM_1 PF00076.22 KRH92601.1 - 5.5e-14 51.7 0.6 1.4e-13 50.4 0.1 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 KRH92601.1 - 4.2e-06 27.1 0.8 7e-06 26.4 0.8 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Aquarius_N PF16399.5 KRH92601.1 - 0.043 11.9 2.4 0.053 11.6 2.4 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus RGS PF00615.19 KRH92601.1 - 0.098 12.9 0.5 0.19 12.0 0.2 1.6 2 0 0 2 2 2 0 Regulator of G protein signaling domain FANCI_S1-cap PF14674.6 KRH92601.1 - 0.26 11.4 3.8 1.7 8.8 0.3 3.1 3 0 0 3 3 3 0 FANCI solenoid 1 cap Clat_adaptor_s PF01217.20 KRH92602.1 - 0.00012 22.0 3.5 0.00015 21.7 3.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tubulin PF00091.25 KRH92603.1 - 7.5e-63 212.3 0.2 2e-62 210.9 0.2 1.7 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KRH92603.1 - 9.2e-20 71.1 0.3 1.9e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KRH92603.1 - 1.8e-05 25.0 0.1 8.5e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain bcl-2I13 PF12201.8 KRH92603.1 - 0.00038 20.4 0.0 0.00081 19.3 0.0 1.6 1 1 0 1 1 1 1 Bcl2-interacting killer, BH3-domain containing Tubulin_3 PF14881.6 KRH92603.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KRH92603.1 - 0.0078 15.4 0.1 0.024 13.8 0.0 1.7 1 1 0 1 1 1 1 Tubulin like Turandot PF07240.11 KRH92603.1 - 0.028 14.4 0.5 0.11 12.4 0.3 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Tox-REase-5 PF15648.6 KRH92604.1 - 0.19 12.2 3.4 0.34 11.4 0.9 2.5 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 5 DDE_Tnp_1_7 PF13843.6 KRH92605.1 - 2.3e-32 112.7 5.4 2.6e-32 112.5 5.4 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 KRH92606.1 - 6.2e-10 38.9 0.7 7.6e-10 38.6 0.7 1.1 1 0 0 1 1 1 1 Transposase IS4 Reprolysin_4 PF13583.6 KRH92606.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like KIP1 PF07765.12 KRH92606.1 - 0.1 12.7 1.1 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 KIP1-like protein CLTH PF10607.9 KRH92607.1 - 0.0011 18.9 6.1 0.0028 17.6 6.1 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Glyco_hydro_77 PF02446.17 KRH92607.1 - 0.044 12.6 0.9 0.057 12.3 0.9 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase AvrM-A PF18241.1 KRH92607.1 - 0.36 11.2 6.4 0.9 9.9 6.4 1.7 1 0 0 1 1 1 0 Flax-rust effector AvrM-A Arf PF00025.21 KRH92608.1 - 1.1e-16 60.8 0.2 1.5e-14 53.8 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 KRH92608.1 - 3.4e-06 26.8 0.2 0.033 13.8 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KRH92608.1 - 2.6e-05 24.4 0.9 0.0051 17.0 0.0 2.3 1 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KRH92608.1 - 0.00091 18.7 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 KRH92608.1 - 0.011 15.6 0.9 0.026 14.3 0.2 1.9 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SLATT_6 PF18169.1 KRH92608.1 - 0.027 14.1 2.8 0.21 11.2 0.4 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 FeoB_N PF02421.18 KRH92608.1 - 0.048 13.2 0.0 2.4 7.7 0.1 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.27 KRH92608.1 - 0.098 13.2 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KRH92608.1 - 0.099 12.7 1.0 0.72 10.0 1.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KRH92608.1 - 0.11 12.5 0.5 0.39 10.7 0.1 2.0 1 1 2 3 3 3 0 AAA domain AAA_2 PF07724.14 KRH92608.1 - 0.15 12.2 0.0 6.9 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Gtr1_RagA PF04670.12 KRH92608.1 - 0.19 11.0 2.2 5.2 6.3 2.2 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 KRH92608.1 - 0.58 10.6 4.6 1.1 9.7 0.3 2.2 1 1 1 2 2 2 0 AAA domain RVT_1 PF00078.27 KRH92610.1 - 3.7e-20 72.4 0.0 5.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH92612.1 - 2.5e-17 63.1 0.1 3.9e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KRH92612.1 - 1.8e-06 28.2 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease BCD PF15461.6 KRH92616.1 - 0.011 15.3 1.2 0.012 15.2 1.2 1.0 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase AAA_23 PF13476.6 KRH92617.1 - 2.2e-19 70.7 23.5 2.2e-19 70.7 23.5 4.4 1 1 3 4 4 4 1 AAA domain SMC_N PF02463.19 KRH92617.1 - 1.5e-13 50.7 0.2 1.5e-13 50.7 0.2 4.9 3 1 3 6 6 6 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KRH92617.1 - 3.2e-06 26.8 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KRH92617.1 - 3.1e-05 23.9 54.1 3.1e-05 23.9 54.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 KRH92617.1 - 5.3e-05 22.9 0.1 5.3e-05 22.9 0.1 4.0 3 1 1 5 5 5 1 AAA domain AAA_21 PF13304.6 KRH92617.1 - 0.00097 19.0 8.7 0.00097 19.0 8.7 3.5 1 1 2 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KRH92617.1 - 0.0016 18.9 0.8 0.0016 18.9 0.8 4.3 1 1 1 2 2 2 1 ABC transporter AAA_13 PF13166.6 KRH92617.1 - 0.013 14.2 0.1 0.013 14.2 0.1 3.9 2 1 2 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 KRH92617.1 - 0.015 15.2 0.0 0.015 15.2 0.0 4.4 2 1 3 5 5 5 0 RsgA GTPase MukB PF04310.12 KRH92617.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.7 2 1 2 4 4 4 0 MukB N-terminal Acetyltransf_15 PF17013.5 KRH92618.1 - 6.5e-25 87.8 5.8 8.9e-25 87.4 5.8 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_7 PF13508.7 KRH92618.1 - 0.0017 18.7 0.0 0.0053 17.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KRH92618.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 KRH92618.1 - 0.11 12.5 0.2 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KRH92618.1 - 0.12 12.6 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family TbpB_C PF17483.2 KRH92618.1 - 0.18 12.2 1.4 0.26 11.7 0.3 1.8 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B rve PF00665.26 KRH92620.1 - 1.6e-05 25.1 0.0 1.7e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.12 KRH92620.1 - 0.042 13.6 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RtcB PF01139.17 KRH92622.1 - 1.3e-50 172.8 0.0 1.5e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB zf-CHCC PF10276.9 KRH92622.1 - 0.031 14.3 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger domain ParA PF10609.9 KRH92623.1 - 1.3e-47 162.3 0.1 1.5e-47 162.2 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KRH92623.1 - 7.7e-09 35.7 1.0 3.4e-07 30.3 1.0 2.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KRH92623.1 - 1.1e-08 35.1 0.0 2.9e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KRH92623.1 - 4.4e-05 22.8 2.5 0.002 17.4 0.4 2.8 1 1 1 3 3 3 2 Anion-transporting ATPase CBP_BcsQ PF06564.12 KRH92623.1 - 0.019 14.4 0.1 0.37 10.2 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 KRH92623.1 - 0.027 14.9 0.1 0.048 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KRH92623.1 - 0.12 12.5 0.3 0.23 11.6 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DUF1574 PF07611.11 KRH92624.1 - 0.039 13.3 2.4 0.04 13.3 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) CSD PF00313.22 KRH92626.1 - 8.7e-15 54.3 0.4 2.5e-13 49.7 0.0 2.3 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KRH92626.1 - 0.07 12.8 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain DSHCT PF08148.12 KRH92628.1 - 4.2e-44 150.1 0.1 7.7e-44 149.2 0.1 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain RecR PF02132.15 KRH92628.1 - 0.017 14.7 3.5 0.72 9.5 3.8 2.8 2 0 0 2 2 2 0 RecR protein Spt5-NGN PF03439.13 KRH92629.1 - 4e-13 49.1 0.7 7.4e-11 41.8 0.7 2.8 1 1 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section LSM14 PF12701.7 KRH92629.1 - 0.00021 21.3 1.8 0.37 10.9 0.1 3.8 3 0 0 3 3 3 2 Scd6-like Sm domain KOW PF00467.29 KRH92629.1 - 0.00043 20.1 8.9 0.078 13.0 0.2 4.1 4 0 0 4 4 4 2 KOW motif DUF2642 PF10842.8 KRH92629.1 - 0.015 15.1 0.4 0.41 10.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) HlyD_3 PF13437.6 KRH92629.1 - 0.05 14.3 0.4 34 5.2 0.1 3.6 2 1 1 3 3 3 0 HlyD family secretion protein NdhS PF11623.8 KRH92629.1 - 0.13 11.9 0.2 18 5.1 0.1 2.9 3 0 0 3 3 3 0 NAD(P)H dehydrogenase subunit S Kinesin PF00225.23 KRH92630.1 - 4.3e-79 265.9 4.8 6.1e-79 265.4 4.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KRH92630.1 - 2.5e-19 69.7 1.8 2.5e-19 69.7 1.8 2.4 2 0 0 2 2 2 1 Microtubule binding DUF2341 PF10102.9 KRH92630.1 - 0.0046 17.5 0.2 0.012 16.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2341) UN_NPL4 PF11543.8 KRH92630.1 - 2.9 8.5 6.4 11 6.6 0.3 3.0 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 LNS2 PF08235.13 KRH92632.1 - 8.7e-50 169.3 0.9 1.8e-49 168.3 0.9 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hydrolase_6 PF13344.6 KRH92632.1 - 0.04 14.0 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA PF00004.29 KRH92633.1 - 6.7e-28 97.7 0.5 2.3e-27 96.0 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH92633.1 - 0.00016 21.7 0.0 0.0057 16.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KRH92633.1 - 0.00025 21.2 0.0 0.00061 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KRH92633.1 - 0.00031 21.0 0.0 0.00088 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KRH92633.1 - 0.00034 20.2 0.1 0.0009 18.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KRH92633.1 - 0.00059 19.6 0.3 0.0017 18.1 0.3 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KRH92633.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zot PF05707.12 KRH92633.1 - 0.0045 16.7 0.1 0.0088 15.7 0.1 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 KRH92633.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KRH92633.1 - 0.014 15.8 0.1 0.12 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 KRH92633.1 - 2.6 8.0 12.3 0.091 12.8 2.2 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KRH92633.1 - 2.7 7.7 8.7 0.095 12.5 0.8 2.5 2 1 0 2 2 2 0 AAA domain PHD PF00628.29 KRH92634.1 - 3.8e-06 26.7 7.7 6.5e-06 25.9 7.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KRH92634.1 - 0.0006 19.3 3.5 0.0012 18.4 3.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF2150 PF09920.9 KRH92634.1 - 0.048 13.6 1.2 0.066 13.2 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) SF1-HH PF16275.5 KRH92634.1 - 0.27 11.6 1.8 0.92 9.9 0.6 2.0 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain DDE_3 PF13358.6 KRH92636.1 - 5.4e-05 23.0 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH92637.1 - 1.4e-09 38.1 2.1 1.4e-09 38.0 0.1 1.9 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.15 KRH92637.1 - 5.9e-05 23.0 0.6 0.013 15.6 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.6 KRH92637.1 - 6.8e-05 23.4 0.0 0.0037 17.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 KRH92637.1 - 0.0023 17.5 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 KRH92637.1 - 0.0051 16.5 0.7 0.011 15.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KRH92637.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_21 PF13276.6 KRH92637.1 - 0.029 14.5 0.1 0.062 13.4 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain Arg_repressor PF01316.21 KRH92637.1 - 0.065 13.0 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain zf-CCCH PF00642.24 KRH92639.1 - 1.2e-17 63.3 26.4 5.3e-10 39.0 7.8 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KRH92639.1 - 2.2e-07 30.7 19.7 6.9e-06 25.9 4.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KRH92639.1 - 1e-06 28.4 14.8 0.00013 21.7 2.1 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KRH92639.1 - 0.016 15.9 13.8 1.1 10.0 3.5 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KRH92639.1 - 0.078 13.2 7.5 0.2 11.9 7.5 1.8 1 1 0 1 1 1 0 Zinc-finger containing family DUF3045 PF11243.8 KRH92639.1 - 0.092 12.9 0.6 0.38 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) zf-CCCH_2 PF14608.6 KRH92639.1 - 0.35 11.4 13.4 0.55 10.8 2.0 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RVT_1 PF00078.27 KRH92640.1 - 1.8e-28 99.6 0.2 2.9e-28 98.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH92640.1 - 3.2e-18 65.6 0.0 6.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92640.1 - 4.2e-10 39.9 0.0 9.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KRH92640.1 - 7.9e-08 32.8 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92640.1 - 2e-07 30.8 0.0 6.1e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH92640.1 - 2.1e-06 28.3 0.0 4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 KRH92640.1 - 0.0011 18.5 0.2 0.004 16.7 0.2 1.9 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) RVT_thumb PF06817.14 KRH92640.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Sec62 PF03839.16 KRH92641.1 - 5.7e-33 114.3 0.8 6.3e-33 114.1 0.8 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.9 KRH92641.1 - 0.035 12.9 0.6 0.041 12.7 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAM76 PF16046.5 KRH92641.1 - 0.14 11.5 5.4 0.19 11.1 5.4 1.0 1 0 0 1 1 1 0 FAM76 protein RELT PF12606.8 KRH92641.1 - 6.6 5.8 6.4 17 4.5 6.4 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 AAA_21 PF13304.6 KRH92643.1 - 3.6e-07 30.3 1.6 7.3e-07 29.3 0.1 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KRH92643.1 - 1.8e-06 27.6 5.0 2.8e-06 26.9 4.8 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KRH92643.1 - 0.0037 17.0 26.1 2.1 7.9 26.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Glyco_hydro_65N PF03636.15 KRH92643.1 - 0.004 16.8 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF678 PF05077.12 KRH92643.1 - 0.08 13.1 0.4 0.08 13.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF678) ABC_tran PF00005.27 KRH92643.1 - 0.096 13.2 3.2 1.2 9.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter PSCyt3 PF07627.11 KRH92643.1 - 0.12 12.7 0.3 0.48 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) DUF4407 PF14362.6 KRH92643.1 - 0.12 11.7 2.6 0.25 10.7 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_8 PF18476.1 KRH92643.1 - 4.6 7.0 17.2 0.054 13.3 6.7 2.8 2 1 1 3 3 3 0 PIN like domain MFMR_assoc PF16596.5 KRH92643.1 - 6.9 7.1 12.4 1.1 9.7 7.4 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR gag-asp_proteas PF13975.6 KRH92644.1 - 3.7e-05 24.2 0.0 5.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92644.1 - 0.00049 19.9 0.2 0.0011 18.8 0.2 1.5 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH92644.1 - 0.0062 16.3 0.1 0.021 14.6 0.1 1.8 1 1 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KRH92644.1 - 0.019 15.6 0.0 0.032 14.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 KRH92645.1 - 1.8e-22 80.0 0.1 2.5e-22 79.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) S1FA PF04689.13 KRH92648.1 - 0.086 13.0 3.4 0.11 12.6 3.4 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Ufd2P_core PF10408.9 KRH92649.1 - 7.1e-34 117.4 16.9 9.7e-34 117.0 16.9 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KRH92649.1 - 8.4e-19 67.5 0.9 2e-18 66.3 0.9 1.7 1 0 0 1 1 1 1 U-box domain DUF2207 PF09972.9 KRH92651.1 - 0.83 8.3 12.9 0.8 8.4 12.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YlaC PF10777.9 KRH92651.1 - 1.6 8.6 7.5 1.7 8.4 7.5 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC Phage_holin_3_6 PF07332.11 KRH92651.1 - 3.9 7.5 6.6 4.7 7.3 6.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III BolA PF01722.18 KRH92652.1 - 3.3e-08 33.7 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein UBA PF00627.31 KRH92653.1 - 1.6e-09 37.4 0.1 4.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KRH92653.1 - 0.0013 18.5 0.8 0.0032 17.3 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like BKACE PF05853.12 KRH92653.1 - 0.009 15.4 5.4 0.015 14.7 5.4 1.5 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme UBA_4 PF14555.6 KRH92653.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain RT_RNaseH_2 PF17919.1 KRH92657.1 - 1.7e-14 53.7 0.1 2e-14 53.5 0.1 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92657.1 - 9.4e-11 41.9 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 KRH92658.1 - 6.2e-28 97.9 0.5 7.6e-28 97.6 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92658.1 - 1.1e-14 54.4 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRH92658.1 - 2.8e-11 42.8 0.1 3.3e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KRH92658.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KRH92658.1 - 0.014 15.0 0.1 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KRH92658.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 KRH92658.1 - 0.029 14.0 0.2 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.23 KRH92658.1 - 0.049 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 KRH92660.1 - 2.8e-14 52.9 0.0 3.1e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92660.1 - 4.3e-11 43.0 0.0 5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1283 PF06932.11 KRH92662.1 - 0.0017 18.5 0.1 0.002 18.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) N-SET PF11764.8 KRH92662.1 - 0.05 13.7 1.1 0.063 13.4 1.1 1.4 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N UCH PF00443.29 KRH92664.1 - 5.1e-12 45.8 4.7 1.8e-11 44.0 4.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Scramblase PF03803.15 KRH92664.1 - 0.012 15.0 1.6 0.022 14.0 1.4 1.5 1 1 0 1 1 1 0 Scramblase Flu_B_M2 PF04772.12 KRH92665.1 - 0.18 12.1 1.1 0.25 11.6 1.1 1.3 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) RT_RNaseH PF17917.1 KRH92666.1 - 2.7e-36 124.0 1.7 2.9e-35 120.7 0.1 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92666.1 - 2.2e-29 101.4 0.1 4.6e-29 100.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH92666.1 - 1.1e-13 51.0 0.1 2.4e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH92666.1 - 1e-11 45.0 0.0 3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92666.1 - 0.0028 17.9 0.0 0.0097 16.1 0.0 1.9 1 0 0 1 1 1 1 DDE domain Asp_protease_2 PF13650.6 KRH92667.1 - 9e-09 35.9 0.3 1.8e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH92667.1 - 4.5e-08 33.6 0.6 8.4e-08 32.7 0.6 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 KRH92667.1 - 0.00097 18.7 0.1 0.0026 17.3 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 KRH92667.1 - 0.0011 18.8 0.3 0.002 17.9 0.3 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KRH92667.1 - 0.038 14.3 0.1 0.22 11.9 0.1 2.3 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF4399 PF14347.6 KRH92667.1 - 0.056 13.8 0.0 0.31 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) Asp_protease PF09668.10 KRH92667.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Proteasome PF00227.26 KRH92669.1 - 7e-43 146.3 0.2 8.5e-43 146.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit CTD_bind PF04818.13 KRH92671.1 - 4.3e-07 30.7 3.4 5.5e-07 30.3 2.2 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SAP30_Sin3_bdg PF13867.6 KRH92671.1 - 0.43 10.9 3.3 5 7.5 0.2 2.7 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3102 PF11300.8 KRH92671.1 - 2 8.7 8.7 0.12 12.6 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) Myb_DNA-bind_3 PF12776.7 KRH92671.1 - 4.8 8.2 7.6 0.46 11.5 0.9 2.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain ABC2_membrane PF01061.24 KRH92672.1 - 0.4 10.1 9.8 0.41 10.0 9.8 1.0 1 0 0 1 1 1 0 ABC-2 type transporter Viral_Beta_CD PF04530.12 KRH92673.1 - 0.0026 18.0 2.5 2.9 8.2 0.1 3.3 3 0 0 3 3 3 2 Viral Beta C/D like family Ac81 PF05820.11 KRH92673.1 - 0.12 11.9 0.1 0.12 11.9 0.1 3.5 4 0 0 4 4 4 0 Baculoviridae AC81 FeoB_associated PF12669.7 KRH92673.1 - 0.16 12.4 1.4 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Orf78 PF06024.12 KRH92673.1 - 0.26 11.6 17.0 0.19 12.0 1.0 4.3 3 1 1 4 4 4 0 Orf78 (ac78) Glycophorin_A PF01102.18 KRH92673.1 - 3.1 8.1 9.8 2.7 8.3 0.1 3.6 3 2 2 5 5 5 0 Glycophorin A UCH PF00443.29 KRH92677.1 - 8.7e-12 45.1 4.4 1.8e-06 27.6 0.3 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH92677.1 - 0.11 12.1 2.4 0.68 9.5 0.1 2.3 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Sulfate_transp PF00916.20 KRH92678.1 - 1.8e-19 69.8 21.9 3.7e-17 62.2 6.8 2.4 2 1 0 2 2 2 2 Sulfate permease family Paramyx_P_V_C PF03210.13 KRH92678.1 - 0.027 14.3 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal AAA PF00004.29 KRH92679.1 - 6.6e-45 152.8 0.2 2.7e-44 150.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH92679.1 - 5.7e-11 42.0 0.5 1.4e-10 40.8 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KRH92679.1 - 3.5e-08 33.3 0.1 7.9e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KRH92679.1 - 8.6e-08 32.3 0.0 2.7e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KRH92679.1 - 3.8e-07 30.4 0.0 9.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KRH92679.1 - 1e-06 29.2 0.2 6e-05 23.5 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KRH92679.1 - 6.5e-06 26.5 0.6 0.0067 16.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KRH92679.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KRH92679.1 - 0.00021 21.8 0.3 0.012 16.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KRH92679.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KRH92679.1 - 0.0022 17.2 0.4 0.0065 15.7 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KRH92679.1 - 0.0026 18.0 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KRH92679.1 - 0.0027 17.5 0.0 0.0082 16.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4201 PF13870.6 KRH92679.1 - 0.0043 16.8 3.2 0.009 15.8 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) AAA_14 PF13173.6 KRH92679.1 - 0.0047 17.0 0.3 0.072 13.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KRH92679.1 - 0.0051 16.5 0.2 0.098 12.4 0.0 2.9 3 1 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.16 KRH92679.1 - 0.006 16.1 0.1 0.14 11.6 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KRH92679.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KRH92679.1 - 0.01 15.2 0.1 0.027 13.9 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KRH92679.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KRH92679.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KRH92679.1 - 0.014 15.2 0.0 0.099 12.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KRH92679.1 - 0.015 14.7 2.1 0.05 12.9 0.1 2.6 2 1 0 3 3 3 0 KaiC AAA_11 PF13086.6 KRH92679.1 - 0.024 14.4 0.4 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KRH92679.1 - 0.026 13.8 0.1 0.089 12.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KRH92679.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KRH92679.1 - 0.041 13.5 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KRH92679.1 - 0.042 13.0 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF724 PF05266.14 KRH92679.1 - 0.043 13.6 1.0 0.091 12.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NACHT PF05729.12 KRH92679.1 - 0.048 13.6 0.0 0.62 10.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain APG6_N PF17675.1 KRH92679.1 - 0.049 14.2 1.0 0.11 13.0 1.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region RNA_helicase PF00910.22 KRH92679.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 KRH92679.1 - 0.055 12.1 1.5 3.1 6.3 1.7 2.2 2 0 0 2 2 2 0 AAA domain RPA_C PF08784.11 KRH92679.1 - 0.081 13.6 0.0 0.82 10.4 0.0 2.3 2 0 0 2 2 2 0 Replication protein A C terminal DUF374 PF04028.13 KRH92679.1 - 0.13 11.8 0.2 12 5.6 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF374) ABC_tran PF00005.27 KRH92679.1 - 0.15 12.5 0.7 0.69 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DUF4743 PF15916.5 KRH92679.1 - 0.16 11.9 0.2 0.5 10.3 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4743) Laminin_II PF06009.12 KRH92679.1 - 0.23 11.5 5.8 2.2 8.3 1.5 2.9 3 0 0 3 3 2 0 Laminin Domain II DivIC PF04977.15 KRH92679.1 - 0.51 10.2 5.4 0.21 11.4 2.9 1.7 2 0 0 2 2 1 0 Septum formation initiator Fib_alpha PF08702.10 KRH92679.1 - 0.61 10.3 3.0 0.7 10.1 0.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_17 PF13207.6 KRH92679.1 - 0.7 10.3 4.5 1.9 8.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain Syja_N PF02383.18 KRH92680.1 - 3.2e-16 59.5 0.0 3.2e-16 59.5 0.0 2.2 2 1 0 2 2 2 1 SacI homology domain DUF240 PF03086.14 KRH92680.1 - 0.0055 16.6 3.0 0.015 15.2 3.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF240) SNARE_assoc PF09335.11 KRH92680.1 - 0.15 12.5 4.7 0.36 11.3 4.7 1.6 1 1 0 1 1 1 0 SNARE associated Golgi protein RtcB PF01139.17 KRH92681.1 - 4.2e-27 95.4 10.6 5.4e-27 95.0 1.3 2.7 2 1 0 2 2 2 1 tRNA-splicing ligase RtcB RP854 PF17460.2 KRH92681.1 - 0.0078 16.0 0.7 0.012 15.3 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized protein RP854 Membralin PF09746.9 KRH92681.1 - 1.9 7.5 6.5 2.6 7.0 6.5 1.2 1 0 0 1 1 1 0 Tumour-associated protein RAG1_imp_bd PF12560.8 KRH92683.1 - 0.044 13.3 0.4 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 RAG1 importin binding PAH PF02671.21 KRH92685.1 - 1.1e-12 47.9 0.0 2.2e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Paired amphipathic helix repeat BBS2_Mid PF14783.6 KRH92687.1 - 0.054 13.5 3.5 1.1 9.3 0.2 3.5 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Presenilin PF01080.17 KRH92687.1 - 3.8 6.2 5.5 5.3 5.7 5.5 1.2 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.20 KRH92688.1 - 2.8e-156 521.2 5.6 3.5e-156 520.9 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KRH92688.1 - 3.6e-11 42.5 0.1 7.1e-07 28.3 0.0 2.6 1 1 1 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KRH92688.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KRH92688.1 - 0.00093 19.6 0.8 0.11 12.9 0.0 2.7 2 1 0 2 2 2 1 Cell division protein FtsA DDR PF08841.10 KRH92688.1 - 0.027 13.5 0.1 0.72 8.8 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Pkinase PF00069.25 KRH92689.1 - 1.7e-33 116.1 4.1 2.4e-33 115.6 4.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92689.1 - 4.1e-18 65.6 0.5 5.8e-18 65.1 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH92689.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like ApoC-I PF04691.12 KRH92690.1 - 0.0041 17.0 0.4 0.0058 16.5 0.3 1.4 1 1 0 1 1 1 1 Apolipoprotein C-I (ApoC-1) WXG100 PF06013.12 KRH92690.1 - 0.017 15.3 0.2 0.018 15.3 0.2 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF1366 PF07104.11 KRH92690.1 - 0.19 11.4 4.9 0.22 11.3 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) MtrG PF04210.13 KRH92690.1 - 0.23 11.3 0.8 0.26 11.1 0.8 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2951 PF11166.8 KRH92690.1 - 0.71 10.1 6.4 0.72 10.1 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF3450 PF11932.8 KRH92691.1 - 2.2 7.5 15.8 5.2 6.3 9.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 KRH92691.1 - 3.1 6.6 6.7 3.5 6.4 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1451 PF07295.11 KRH92691.1 - 6.5 6.8 8.9 5.7 7.0 5.6 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain DHR10 PF18595.1 KRH92691.1 - 7.8 6.6 20.8 2 8.5 12.2 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain AAA_11 PF13086.6 KRH92692.1 - 2.3e-25 89.9 5.3 9e-25 87.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KRH92692.1 - 6e-24 84.8 0.1 6e-24 84.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KRH92693.1 - 0.0017 18.8 1.7 0.3 11.5 0.0 3.0 1 1 2 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KRH92693.1 - 0.0099 15.1 0.3 0.021 14.0 0.3 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KRH92693.1 - 0.014 15.7 1.6 2 8.7 0.0 2.9 1 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KRH92693.1 - 0.042 14.2 1.4 0.16 12.3 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 KRH92693.1 - 0.058 13.9 0.2 0.19 12.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain Ku_PK_bind PF08785.11 KRH92693.1 - 0.067 13.3 3.4 0.45 10.7 1.8 2.7 2 1 0 2 2 2 0 Ku C terminal domain like AAA_11 PF13086.6 KRH92693.1 - 0.11 12.2 7.0 1.6 8.5 7.0 2.0 1 1 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.6 KRH92693.1 - 0.13 12.4 1.3 2.2 8.5 1.3 2.7 1 1 0 1 1 1 0 Sperm tail C-terminal domain ESM4 PF15952.5 KRH92693.1 - 0.17 12.3 3.4 0.26 11.7 3.4 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family RNA_helicase PF00910.22 KRH92693.1 - 0.19 12.1 2.8 0.5 10.8 1.0 2.5 1 1 0 2 2 2 0 RNA helicase LEH PF07858.12 KRH92694.1 - 0.082 13.0 0.1 0.082 13.0 0.1 1.0 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Peptidase_S8 PF00082.22 KRH92696.1 - 1.5e-33 116.4 0.2 3.1e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 KRH92696.1 - 4.1e-06 27.4 0.3 1.1e-05 26.0 0.3 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 AAA_lid_3 PF17862.1 KRH92696.1 - 0.024 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA+ lid domain Glyco_transf_15 PF01793.16 KRH92697.1 - 5.6e-98 328.2 16.1 7.1e-98 327.8 16.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF412 PF04217.13 KRH92698.1 - 0.61 10.0 3.0 0.74 9.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF412 NMT1 PF09084.11 KRH92699.1 - 0.00044 20.3 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 NMT1/THI5 like TPR_1 PF00515.28 KRH92699.1 - 0.00055 19.6 0.2 0.11 12.4 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KRH92699.1 - 0.03 14.8 0.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat FliG_N PF14842.6 KRH92699.1 - 0.046 14.3 0.1 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 FliG N-terminal domain TPR_8 PF13181.6 KRH92699.1 - 0.058 13.6 1.2 9.4 6.7 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat VPS13_C PF16909.5 KRH92700.1 - 1.2e-25 90.3 16.9 2.2e-22 79.7 5.0 3.3 3 1 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KRH92700.1 - 0.0089 16.4 0.0 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF1451 PF07295.11 KRH92700.1 - 0.51 10.4 3.8 1.1 9.3 3.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain YtxH PF12732.7 KRH92700.1 - 0.58 10.7 10.5 0.24 12.0 6.6 2.3 1 1 1 2 2 2 0 YtxH-like protein HIT PF01230.23 KRH92701.1 - 3.6e-18 66.1 1.1 5.3e-18 65.6 1.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KRH92701.1 - 4.1e-05 24.0 0.7 6e-05 23.5 0.7 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding WD40 PF00400.32 KRH92702.1 - 1.2e-10 41.8 3.3 0.0022 18.8 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40_like PF17005.5 KRH92702.1 - 0.0003 20.2 2.3 0.0016 17.8 2.3 2.0 1 1 0 1 1 1 1 WD40-like domain FAM150 PF15129.6 KRH92702.1 - 0.032 14.4 5.9 0.56 10.4 0.0 3.1 2 1 1 3 3 3 0 FAM150 family DDE_3 PF13358.6 KRH92703.1 - 2.3e-13 50.1 0.0 2.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cytotoxic PF09000.10 KRH92703.1 - 0.066 13.6 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytotoxic Topoisom_I PF01028.20 KRH92703.1 - 0.07 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core ATP_bind_1 PF03029.17 KRH92704.1 - 2.4e-16 60.3 0.1 2.7e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KRH92704.1 - 0.0084 15.7 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 KRH92704.1 - 0.029 14.2 0.7 0.11 12.3 0.7 1.9 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Ras PF00071.22 KRH92704.1 - 0.063 12.9 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family Exo_endo_phos PF03372.23 KRH92705.1 - 1.8e-05 24.4 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RCC1 PF00415.18 KRH92706.1 - 2.7e-19 69.5 0.2 3e-06 27.8 0.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KRH92706.1 - 2.9e-11 42.9 4.3 0.019 14.7 0.1 4.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Pentapeptide PF00805.22 KRH92707.1 - 1.8e-07 30.6 0.9 4.6e-07 29.3 0.5 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KRH92707.1 - 8.2e-06 25.9 4.3 8.1e-05 22.7 3.5 2.8 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) DUF948 PF06103.11 KRH92707.1 - 0.12 12.7 5.1 0.55 10.5 1.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GCS PF03074.16 KRH92708.1 - 9.4e-34 117.4 11.0 1.3e-33 116.9 9.5 1.9 2 1 0 2 2 2 1 Glutamate-cysteine ligase Arm-DNA-bind_2 PF12167.8 KRH92709.1 - 0.051 13.5 0.1 0.067 13.1 0.1 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain RT_RNaseH PF17917.1 KRH92710.1 - 8.3e-27 93.5 0.0 4.4e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92710.1 - 3.6e-26 91.1 0.0 8.1e-26 90.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH92710.1 - 4.7e-19 68.7 0.0 1.4e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92710.1 - 6.9e-10 38.9 0.0 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 KRH92710.1 - 0.0072 16.2 0.4 0.027 14.3 0.2 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 KRH92710.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain MFS_1_like PF12832.7 KRH92711.1 - 8.1e-15 54.6 27.2 1.1e-14 54.1 27.2 1.1 1 0 0 1 1 1 1 MFS_1 like family TFIIB PF00382.19 KRH92712.1 - 3.2e-37 126.4 0.5 5.6e-21 74.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KRH92712.1 - 1.1e-06 28.0 0.1 2.2e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KRH92712.1 - 0.00042 20.4 0.7 0.0051 16.8 0.1 2.1 1 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KRH92712.1 - 0.0013 18.8 0.1 0.11 12.6 0.0 2.3 1 1 1 2 2 2 1 Cyclin, C-terminal domain HARE-HTH PF05066.13 KRH92712.1 - 0.019 15.4 0.1 5.3 7.5 0.1 2.4 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain DUF4370 PF14290.6 KRH92712.1 - 0.023 14.5 0.1 0.053 13.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4370) SoPB_HTH PF18090.1 KRH92712.1 - 0.092 12.9 0.2 1.3 9.2 0.0 2.6 2 1 1 3 3 3 0 Centromere-binding protein HTH domain RVT_1 PF00078.27 KRH92714.1 - 6.2e-14 52.0 0.1 7.2e-14 51.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH92715.1 - 2.3e-08 34.0 0.0 2.4e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92715.1 - 0.00019 21.7 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_M48 PF01435.18 KRH92716.1 - 2.3e-12 47.1 0.1 5.3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_A2B PF12384.8 KRH92717.1 - 2.9e-06 27.0 0.0 4.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 KRH92717.1 - 4.2e-06 27.3 0.0 0.00012 22.7 0.0 2.1 1 1 1 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 KRH92717.1 - 6.1e-06 26.0 0.1 1.4e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH92717.1 - 0.021 15.4 0.0 0.34 11.5 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 KRH92718.1 - 8.7e-26 90.8 1.5 2.4e-25 89.4 1.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH92718.1 - 3.5e-09 36.6 0.0 1.2e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92718.1 - 0.00037 20.7 0.0 0.0094 16.2 0.0 2.8 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 KRH92718.1 - 0.00093 19.0 0.3 0.0037 17.1 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase thumb domain sCache_like PF16736.5 KRH92718.1 - 0.13 12.4 2.1 1.4 9.0 0.1 2.7 2 0 0 2 2 2 0 Single Cache-like SHMT PF00464.19 KRH92719.1 - 9.1e-151 502.0 0.1 1.1e-150 501.7 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KRH92719.1 - 0.038 13.2 0.1 0.057 12.6 0.1 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II ribosomal_L24 PF17136.4 KRH92720.1 - 1.3 9.5 4.5 33 5.0 0.2 3.2 2 1 1 3 3 3 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 zf-RING_2 PF13639.6 KRH92721.1 - 2.4e-12 47.0 11.2 3.7e-12 46.4 11.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KRH92721.1 - 1.8e-10 40.4 3.1 1.8e-10 40.4 3.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KRH92721.1 - 1.2e-08 34.7 9.9 2e-08 33.9 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRH92721.1 - 4.3e-08 32.9 9.2 6.8e-08 32.2 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH92721.1 - 1.2e-06 28.3 9.0 2e-06 27.7 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KRH92721.1 - 2.3e-06 27.8 11.3 7.6e-06 26.1 11.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KRH92721.1 - 2.6e-05 24.0 9.4 4.6e-05 23.2 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KRH92721.1 - 4.4e-05 23.5 1.7 8.2e-05 22.6 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KRH92721.1 - 7.6e-05 22.5 8.2 0.00014 21.7 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KRH92721.1 - 0.0016 18.4 8.6 0.0021 18.0 3.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KRH92721.1 - 0.0029 17.2 5.7 0.0045 16.6 5.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KRH92721.1 - 0.031 14.1 8.5 0.057 13.2 8.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KRH92721.1 - 0.077 13.2 7.7 0.48 10.6 7.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KRH92721.1 - 0.8 9.9 10.4 2.8 8.1 10.4 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KRH92721.1 - 4.1 7.8 9.3 8.6 6.8 9.3 1.6 1 1 0 1 1 1 0 RING-like domain TLC PF03219.14 KRH92723.1 - 9e-52 176.4 25.5 1.2e-51 176.0 25.5 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF1283 PF06932.11 KRH92724.1 - 0.0028 17.8 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) rve_3 PF13683.6 KRH92725.1 - 9.3e-05 22.1 0.2 0.00022 20.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 KRH92725.1 - 0.00052 20.2 0.1 0.0015 18.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92725.1 - 0.039 14.2 0.6 0.57 10.4 0.1 2.0 2 0 0 2 2 2 0 DDE domain Sad1_UNC PF07738.13 KRH92727.1 - 2.5e-09 37.3 2.0 3.9e-09 36.6 2.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF5537 PF17690.1 KRH92727.1 - 0.12 12.0 0.1 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5537) Retrotrans_gag PF03732.17 KRH92731.1 - 0.032 14.5 0.2 0.044 14.0 0.2 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein PNMA PF14893.6 KRH92731.1 - 0.075 12.4 0.0 0.085 12.2 0.0 1.0 1 0 0 1 1 1 0 PNMA Pro_isomerase PF00160.21 KRH92732.1 - 7.2e-38 130.3 1.4 8.8e-38 130.1 1.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMP_synt_C PF00958.22 KRH92732.1 - 0.12 12.4 0.1 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF5100 PF17029.5 KRH92734.1 - 2.5e-25 88.7 6.6 2.8e-25 88.6 6.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5100) DnaB_C PF03796.15 KRH92734.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain THB PF18362.1 KRH92734.1 - 0.29 10.8 2.6 13 5.5 0.1 2.6 1 1 1 2 2 2 0 Tri-helix bundle domain Prok-RING_1 PF14446.6 KRH92735.1 - 0.14 12.1 0.4 0.25 11.3 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 NPV_P10 PF05531.12 KRH92737.1 - 6.7 7.2 21.4 2.4 8.7 0.1 5.1 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein OTT_1508_deam PF14441.6 KRH92738.1 - 0.06 13.4 0.2 0.068 13.2 0.2 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase Ribosomal_S3_C PF00189.20 KRH92739.1 - 7.1e-17 61.7 2.3 1.4e-16 60.7 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain HATPase_c_3 PF13589.6 KRH92740.1 - 1.2e-12 47.8 0.6 2e-12 47.1 0.6 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KRH92740.1 - 1.4e-05 25.6 1.1 3.4e-05 24.3 1.1 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L11_N PF03946.14 KRH92741.1 - 4.9e-17 61.5 0.2 8.8e-17 60.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KRH92741.1 - 1.7e-15 57.2 0.2 3.8e-15 56.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Helicase_C PF00271.31 KRH92743.1 - 5.3e-17 62.2 0.0 6.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Topoisom_bac PF01131.20 KRH92744.1 - 4.4e-61 207.1 0.7 6.1e-33 114.4 0.4 3.2 1 1 1 2 2 2 2 DNA topoisomerase zf-GRF PF06839.12 KRH92744.1 - 3e-07 30.4 5.7 3e-07 30.4 5.7 2.6 2 0 0 2 2 2 1 GRF zinc finger Lamprin PF06403.11 KRH92744.1 - 1.2 9.1 8.6 1.9 8.4 8.6 1.2 1 0 0 1 1 1 0 Lamprin Guanylate_kin PF00625.21 KRH92745.1 - 5e-35 120.8 0.6 5.7e-35 120.6 0.6 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KRH92745.1 - 3.5e-06 27.6 1.3 6.2e-06 26.8 1.2 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KRH92745.1 - 9.4e-05 22.5 0.2 0.00016 21.7 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KRH92745.1 - 0.0019 18.4 0.4 0.11 12.6 0.1 2.2 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KRH92745.1 - 0.0021 18.6 4.2 0.013 16.0 4.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KRH92745.1 - 0.0022 17.7 1.0 0.0058 16.3 1.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KRH92745.1 - 0.0031 17.3 0.1 0.0097 15.7 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KRH92745.1 - 0.0035 16.4 0.2 0.0056 15.8 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KRH92745.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 KRH92745.1 - 0.012 15.6 0.5 0.021 14.8 0.1 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 KRH92745.1 - 0.012 15.8 0.0 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KRH92745.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.7 1 1 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 KRH92745.1 - 0.016 14.5 0.1 0.078 12.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KRH92745.1 - 0.02 14.5 0.6 0.22 11.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KRH92745.1 - 0.026 14.5 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Thymidylate_kin PF02223.17 KRH92745.1 - 0.031 14.0 2.0 0.8 9.3 2.0 2.2 1 1 0 1 1 1 0 Thymidylate kinase DUF815 PF05673.13 KRH92745.1 - 0.04 13.1 0.1 0.09 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KRH92745.1 - 0.045 13.7 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KRH92745.1 - 0.048 14.1 1.3 0.33 11.4 1.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KRH92745.1 - 0.049 13.7 0.2 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Adenylate kinase TrwB_AAD_bind PF10412.9 KRH92745.1 - 0.059 12.3 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 KRH92745.1 - 0.062 12.2 2.1 1.5 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_7 PF12775.7 KRH92745.1 - 0.077 12.5 0.8 0.16 11.5 0.1 1.9 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF3987 PF13148.6 KRH92745.1 - 0.11 11.5 0.1 2.6 7.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.14 KRH92745.1 - 0.11 12.4 0.3 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B dNK PF01712.19 KRH92745.1 - 0.12 12.2 7.2 0.9 9.3 0.3 2.9 1 1 2 3 3 3 0 Deoxynucleoside kinase AAA_17 PF13207.6 KRH92745.1 - 0.14 12.6 0.5 5.5 7.4 0.4 2.7 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KRH92745.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 KRH92745.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.1 2 1 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KRH92745.1 - 0.21 11.8 0.4 0.4 10.9 0.1 1.6 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 KRH92745.1 - 0.42 10.6 3.2 1.9 8.5 3.2 1.9 1 1 0 1 1 1 0 Dynamin family Cecropin PF00272.19 KRH92745.1 - 0.46 10.3 4.3 10 6.0 0.8 2.5 2 0 0 2 2 2 0 Cecropin family FtsK_SpoIIIE PF01580.18 KRH92745.1 - 0.6 9.4 3.0 0.3 10.4 0.7 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KRH92745.1 - 0.91 9.6 7.7 0.22 11.6 0.7 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_14 PF13173.6 KRH92745.1 - 1.1 9.3 5.5 1.7 8.7 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KRH92745.1 - 4.3 7.8 15.9 3.8e+02 1.4 15.9 2.2 1 1 0 1 1 1 0 AAA domain DUF4105 PF13387.6 KRH92749.1 - 0.002 17.8 0.8 0.0045 16.6 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) FliL PF03748.14 KRH92749.1 - 0.027 15.1 2.4 0.029 14.9 0.1 2.4 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL ATP-synt_ab PF00006.25 KRH92750.1 - 2e-108 361.0 0.0 2.9e-108 360.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KRH92750.1 - 4.8e-40 136.2 0.6 2e-37 127.7 0.6 2.5 1 1 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KRH92750.1 - 7.7e-12 45.6 0.4 1.7e-11 44.4 0.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Metallophos PF00149.28 KRH92751.1 - 1.1e-38 133.9 0.2 1.4e-38 133.4 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KRH92751.1 - 4.9e-15 55.7 4.5 6.3e-15 55.4 2.9 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PMM PF03332.13 KRH92752.1 - 0.075 12.8 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase HTH_Tnp_Tc3_2 PF01498.18 KRH92753.1 - 1.6e-09 37.9 6.2 1.7e-08 34.6 2.5 2.2 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 KRH92753.1 - 1.1e-06 29.2 5.0 1.5e-05 25.5 0.3 2.5 3 0 0 3 3 3 2 Homeodomain-like domain HTH_11 PF08279.12 KRH92753.1 - 0.00017 21.5 1.0 0.003 17.5 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_7 PF02796.15 KRH92753.1 - 0.013 15.6 0.8 0.46 10.6 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase HTH_21 PF13276.6 KRH92753.1 - 0.018 15.2 0.3 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 HTH-like domain Sigma70_ECF PF07638.11 KRH92753.1 - 0.051 13.5 0.1 0.072 13.0 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_29 PF13551.6 KRH92753.1 - 0.082 12.9 0.8 0.17 11.9 0.2 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Nop PF01798.18 KRH92754.1 - 5e-11 42.5 2.5 8.6e-11 41.7 2.5 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DDE_Tnp_IS1595 PF12762.7 KRH92755.1 - 1.2e-20 74.0 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Synapsin PF02078.16 KRH92755.1 - 0.09 13.1 0.3 0.35 11.2 0.1 1.9 1 1 0 2 2 2 0 Synapsin, N-terminal domain NIF PF03031.18 KRH92756.1 - 1.5e-15 57.3 4.3 9.1e-15 54.8 0.9 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Glyco_hydro_129 PF11308.8 KRH92756.1 - 0.088 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Ribosomal_L3 PF00297.22 KRH92757.1 - 3e-23 82.4 0.0 3.3e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Cpn60_TCP1 PF00118.24 KRH92759.1 - 1.2e-64 218.8 10.5 8.1e-61 206.1 6.2 2.4 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family KHA PF11834.8 KRH92759.1 - 0.032 14.3 0.1 14 5.9 0.0 2.8 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel pXO2-34 PF17362.2 KRH92759.1 - 0.041 13.7 1.1 0.57 10.1 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function gag-asp_proteas PF13975.6 KRH92760.1 - 4.9e-13 49.4 0.0 9.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92760.1 - 1.6e-08 35.1 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH92760.1 - 4.7e-07 29.6 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KRH92760.1 - 0.027 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 KRH92760.1 - 0.043 13.6 0.2 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 Aspartyl protease RsgA_GTPase PF03193.16 KRH92762.1 - 0.058 13.3 0.1 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase Haemocyan_bet_s PF14830.6 KRH92762.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Haemocyanin beta-sandwich DDE_3 PF13358.6 KRH92763.1 - 0.00058 19.6 0.0 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Tyrosinase PF00264.20 KRH92765.1 - 2.5e-30 106.4 0.8 9.7e-30 104.5 0.0 2.3 1 1 1 2 2 2 1 Common central domain of tyrosinase CRISPR_Cas2 PF09827.9 KRH92765.1 - 0.01 16.0 0.9 0.25 11.5 0.6 2.9 2 0 0 2 2 2 0 CRISPR associated protein Cas2 RT_RNaseH_2 PF17919.1 KRH92766.1 - 2.9e-26 91.4 0.1 4.5e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH92766.1 - 1.1e-25 90.0 0.0 1.7e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92766.1 - 0.0056 16.2 0.1 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KRH92767.1 - 4.3e-07 30.4 0.0 8.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH92767.1 - 4.4e-07 29.7 0.5 7.5e-07 29.0 0.5 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 KRH92767.1 - 2.3e-06 27.3 0.8 5.4e-05 22.8 0.3 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 KRH92767.1 - 6.4e-06 26.7 0.0 1.2e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KRH92767.1 - 0.00023 21.0 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH92767.1 - 0.0063 16.8 0.1 0.018 15.4 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Metallophos PF00149.28 KRH92768.1 - 2.7e-26 93.4 0.7 3.6e-26 93.0 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RSN1_7TM PF02714.15 KRH92770.1 - 6e-46 157.0 33.0 1e-45 156.2 33.0 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Occludin_ELL PF07303.13 KRH92770.1 - 0.015 16.0 0.5 0.015 16.0 0.5 2.5 1 1 1 2 2 2 0 Occludin homology domain PHM7_cyt PF14703.6 KRH92770.1 - 0.03 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DivIC PF04977.15 KRH92770.1 - 0.45 10.3 4.8 0.18 11.6 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator Piwi PF02171.17 KRH92774.1 - 3.1e-70 236.8 6.2 5.1e-69 232.8 6.2 2.1 1 1 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KRH92774.1 - 8e-08 32.4 0.3 4.7e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KRH92774.1 - 0.012 15.9 0.0 0.53 10.7 0.0 3.0 2 0 0 2 2 2 0 Argonaute linker 2 domain DUF5344 PF17279.2 KRH92774.1 - 9.8 6.8 8.6 11 6.7 0.2 3.5 3 1 1 4 4 4 0 Family of unknown function (DUF5344) Regnase_1_C PF18561.1 KRH92775.1 - 0.9 9.3 2.9 20 5.0 0.3 2.5 2 0 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain MBOAT PF03062.19 KRH92777.1 - 2.1e-11 43.8 46.0 6.7e-11 42.1 46.0 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KRH92777.1 - 0.00024 21.3 5.6 0.00077 19.7 5.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PARP_reg PF02877.14 KRH92777.1 - 0.03 14.4 0.2 0.063 13.4 0.2 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain HTH_micro PF17007.5 KRH92778.1 - 9.7e-130 433.4 39.9 7.7e-121 404.1 34.2 2.4 2 1 0 2 2 2 2 HTH-like B-block_TFIIIC PF04182.12 KRH92778.1 - 0.0053 16.9 0.1 0.019 15.1 0.1 2.0 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Sel1 PF08238.12 KRH92779.1 - 1.5e-85 279.7 30.9 6.7e-08 33.0 0.1 13.8 14 0 0 14 14 14 13 Sel1 repeat TPR_17 PF13431.6 KRH92779.1 - 3.5 8.2 18.6 39 4.9 0.2 8.5 9 2 1 10 10 10 0 Tetratricopeptide repeat COG5 PF10392.9 KRH92780.1 - 0.0013 18.9 0.1 0.0017 18.5 0.1 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 zf-CCHC PF00098.23 KRH92781.1 - 5.6e-06 26.2 2.4 5.6e-06 26.2 2.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH92781.1 - 0.0034 17.1 1.8 0.007 16.1 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KRH92781.1 - 6.2 6.8 9.2 3.7 7.5 3.3 2.9 2 1 0 2 2 2 0 Zinc knuckle tRNA-synt_1 PF00133.22 KRH92782.1 - 2.3e-135 452.2 4.3 2.3e-135 452.2 4.3 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KRH92782.1 - 2.2e-16 59.6 5.9 3.4e-11 42.5 1.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KRH92782.1 - 5.8e-08 32.5 7.4 1.2e-06 28.2 0.0 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1c PF00749.21 KRH92782.1 - 1 8.2 13.3 0.68 8.8 0.0 3.2 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Selenoprotein_S PF06936.11 KRH92782.1 - 9.1 6.0 12.7 16 5.2 12.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1730 PF08331.10 KRH92783.1 - 0.025 14.5 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) SF3a60_bindingd PF12108.8 KRH92783.1 - 0.91 9.5 4.0 1.8 8.5 3.0 2.1 1 1 0 1 1 1 0 Splicing factor SF3a60 binding domain SPT16 PF08644.11 KRH92784.1 - 4.8e-18 65.8 12.7 4.8e-18 65.8 12.7 4.2 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 KRH92784.1 - 1.6e-12 47.7 1.1 1.6e-12 47.7 1.1 4.2 4 1 0 4 4 4 1 Histone chaperone Rttp106-like PAPS_reduct PF01507.19 KRH92784.1 - 0.51 10.3 7.5 7.9 6.5 0.3 2.7 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family CTP_transf_like PF01467.26 KRH92785.1 - 2.5e-28 99.1 0.3 2.4e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KRH92785.1 - 2.8e-06 27.3 1.5 0.11 12.4 0.2 3.1 3 0 0 3 3 3 2 FAD synthetase UQ_con PF00179.26 KRH92788.1 - 7.3e-47 158.5 0.1 8.4e-47 158.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRH92788.1 - 0.00022 20.9 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Myb_DNA-binding PF00249.31 KRH92789.1 - 3.5e-05 23.9 0.3 7.3e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRH92789.1 - 0.00046 20.4 0.4 0.00094 19.4 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KRH92789.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 KRH92789.1 - 0.018 15.0 0.1 0.043 13.9 0.1 1.8 1 1 0 1 1 1 0 SLIDE Myb_DNA-bind_7 PF15963.5 KRH92789.1 - 2.8 7.9 7.0 0.13 12.2 0.5 2.0 2 0 0 2 2 2 0 Myb DNA-binding like MFS_1_like PF12832.7 KRH92790.1 - 9.1e-18 64.3 5.3 1.6e-17 63.5 5.3 1.3 1 0 0 1 1 1 1 MFS_1 like family Babuvirus_MP PF07234.11 KRH92790.1 - 0.13 12.4 1.4 0.28 11.4 0.5 2.1 1 1 0 1 1 1 0 Movement and RNA silencing protein RT_RNaseH PF17917.1 KRH92791.1 - 7.9e-37 125.7 3.5 7.6e-36 122.6 0.5 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92791.1 - 8.7e-30 102.7 0.2 8.7e-30 102.7 0.2 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92791.1 - 5.5e-29 101.3 0.7 5.5e-29 101.3 0.7 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KRH92791.1 - 2.2e-08 34.3 0.0 5.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH92791.1 - 2.1e-07 31.4 0.0 4.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92791.1 - 1.5e-06 28.7 0.0 3.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Spuma_A9PTase PF03539.14 KRH92791.1 - 3.3e-05 24.1 0.4 8.2e-05 22.8 0.4 1.7 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) RVP_2 PF08284.11 KRH92791.1 - 7.5e-05 22.5 0.2 0.00015 21.5 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH92791.1 - 0.0033 17.2 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease IFT20 PF14931.6 KRH92791.1 - 0.14 12.4 4.0 0.58 10.3 0.3 2.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 MFS_1_like PF12832.7 KRH92792.1 - 9.6e-16 57.6 25.5 1.4e-15 57.1 25.5 1.2 1 0 0 1 1 1 1 MFS_1 like family GRAB PF10375.9 KRH92792.1 - 1.4 8.9 4.4 9 6.3 0.7 3.0 3 0 0 3 3 3 0 GRIP-related Arf-binding domain zf-RING_UBOX PF13445.6 KRH92793.1 - 0.00093 19.2 1.6 0.001 19.0 1.6 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KRH92793.1 - 0.0025 17.7 4.6 0.0062 16.5 4.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KRH92793.1 - 0.006 16.9 3.5 0.011 16.1 3.5 1.6 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KRH92793.1 - 0.0075 16.1 1.8 0.013 15.4 1.8 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 MCM PF00493.23 KRH92794.1 - 3.9e-26 91.5 0.1 4.8e-20 71.6 0.0 3.0 2 1 0 2 2 2 2 MCM P-loop domain MCM_lid PF17855.1 KRH92794.1 - 1.8e-11 44.3 1.1 4.9e-11 42.9 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain RuvB_N PF05496.12 KRH92794.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KRH92794.1 - 0.0099 16.3 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KRH92794.1 - 0.024 14.0 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FERM_F2 PF18377.1 KRH92794.1 - 0.14 12.1 0.7 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 FERM F2 acyl-CoA binding protein-like domain CH PF00307.31 KRH92795.1 - 1.5e-29 102.3 21.4 3.6e-16 59.3 0.3 4.2 5 1 0 5 5 5 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KRH92795.1 - 2.3e-05 24.1 3.3 0.0036 17.1 0.1 3.6 4 1 0 4 4 4 2 CAMSAP CH domain FliS PF02561.14 KRH92795.1 - 0.022 15.0 1.9 0.1 12.9 0.4 2.7 2 0 0 2 2 2 0 Flagellar protein FliS DUF349 PF03993.12 KRH92795.1 - 0.03 14.6 0.6 0.03 14.6 0.6 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) MMR_HSR1 PF01926.23 KRH92796.1 - 2.5e-11 43.6 1.3 8.9e-11 41.9 0.9 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KRH92796.1 - 0.0014 18.2 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.22 KRH92796.1 - 0.023 15.1 0.2 0.092 13.1 0.2 2.1 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 KRH92796.1 - 0.075 12.8 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GATA PF00320.27 KRH92797.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 GATA zinc finger Peptidase_C48 PF02902.19 KRH92798.1 - 8.9e-09 35.5 2.4 2.8e-08 33.9 2.4 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KRH92798.1 - 0.00016 20.6 1.7 0.00016 20.6 1.7 1.6 2 0 0 2 2 2 1 Vaccinia virus I7 processing peptidase UCH PF00443.29 KRH92799.1 - 8.5e-15 54.9 5.8 1.5e-14 54.2 5.8 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH92799.1 - 0.00066 19.4 12.3 0.00066 19.4 12.3 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DNA_pol3_delta PF06144.13 KRH92799.1 - 0.029 14.1 1.4 0.029 14.1 1.4 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Myb_DNA-binding PF00249.31 KRH92800.1 - 0.069 13.4 1.0 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 Myb-like DNA-binding domain DUF2250 PF10007.9 KRH92800.1 - 0.45 10.6 2.8 14 5.9 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) eRF1_2 PF03464.15 KRH92801.1 - 1.6e-32 112.6 0.1 4.9e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 KRH92801.1 - 6.2e-21 75.0 0.9 1.5e-20 73.8 0.9 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KRH92801.1 - 3.8e-16 59.3 0.0 7.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KRH92801.1 - 3e-07 30.8 0.0 4.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KRH92801.1 - 0.0051 17.1 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Far-17a_AIG1 PF04750.14 KRH92802.1 - 5.5e-15 55.2 14.3 7.2e-15 54.8 14.3 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein rve PF00665.26 KRH92803.1 - 1.2e-05 25.4 0.0 1.3e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92803.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Acylphosphatase PF00708.18 KRH92803.1 - 0.052 14.0 0.0 0.056 13.8 0.0 1.0 1 0 0 1 1 1 0 Acylphosphatase RT_RNaseH PF17917.1 KRH92804.1 - 5.9e-12 45.8 0.1 1.2e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92804.1 - 0.0076 16.3 0.2 0.016 15.3 0.1 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF3332 PF11810.8 KRH92804.1 - 0.044 13.4 2.0 0.064 12.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF5401 PF17380.2 KRH92804.1 - 0.54 8.3 16.9 0.61 8.1 16.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RVT_1 PF00078.27 KRH92805.1 - 1e-22 80.7 0.1 1.4e-22 80.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IMS PF00817.20 KRH92806.1 - 1.9e-28 99.3 0.0 5.3e-28 97.9 0.0 1.8 1 1 0 1 1 1 1 impB/mucB/samB family NTPase_P4 PF11602.8 KRH92806.1 - 0.047 12.9 0.1 0.094 11.9 0.1 1.4 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF1805 PF08827.11 KRH92806.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DASH_Dad1 PF08649.10 KRH92806.1 - 0.063 13.5 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 HHH_5 PF14520.6 KRH92806.1 - 0.15 12.7 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L34e PF01199.18 KRH92806.1 - 0.46 10.8 3.7 3.7 7.9 0.1 3.4 3 1 0 3 3 3 0 Ribosomal protein L34e MMM1 PF10296.9 KRH92807.1 - 1.3e-05 24.4 0.1 2.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Ribosomal_L19 PF01245.20 KRH92807.1 - 0.064 13.2 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L19 zf-CCCH PF00642.24 KRH92808.1 - 0.0015 18.4 2.4 0.0046 16.8 2.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Retrotran_gag_2 PF14223.6 KRH92811.1 - 0.0052 16.5 8.8 0.068 12.8 1.4 2.7 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type AAA_23 PF13476.6 KRH92811.1 - 8 6.9 16.3 0.25 11.8 9.7 1.9 2 0 0 2 2 2 0 AAA domain SMI1_KNR4 PF09346.10 KRH92812.1 - 1.1 9.6 7.1 0.19 12.2 2.1 2.3 2 2 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) CENP-H PF05837.12 KRH92812.1 - 4.3 7.8 12.0 0.4 11.1 4.7 2.8 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 KRH92812.1 - 7.2 6.6 26.4 1.3 9.1 8.2 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCS PF03074.16 KRH92813.1 - 5e-33 115.0 8.8 1.2e-32 113.8 8.7 1.4 1 1 0 1 1 1 1 Glutamate-cysteine ligase Helicase_C PF00271.31 KRH92816.1 - 9.3e-30 103.2 0.1 3.2e-29 101.5 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KRH92816.1 - 2.4e-18 66.5 0.1 5.4e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase gag-asp_proteas PF13975.6 KRH92817.1 - 4.9e-08 33.4 0.1 7.4e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92817.1 - 0.00016 22.2 0.1 0.00026 21.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH92817.1 - 0.0008 19.2 0.6 0.0013 18.5 0.6 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH92817.1 - 0.0025 17.6 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF4513 PF14983.6 KRH92817.1 - 0.015 15.4 0.1 0.35 10.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4513) RVP PF00077.20 KRH92817.1 - 0.13 12.6 0.1 0.32 11.3 0.1 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease SUI1 PF01253.22 KRH92820.1 - 9.9e-16 58.0 1.0 1.8e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Translation initiation factor SUI1 Drc1-Sld2 PF11719.8 KRH92820.1 - 0.0017 18.0 6.8 0.002 17.7 6.8 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein CPSF100_C PF13299.6 KRH92820.1 - 0.0037 17.5 1.6 0.0048 17.1 1.6 1.1 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal TORC_M PF12885.7 KRH92820.1 - 0.025 14.5 0.4 0.03 14.2 0.4 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain POPLD PF08170.12 KRH92820.1 - 0.087 13.2 0.2 0.1 13.0 0.2 1.2 1 0 0 1 1 1 0 POPLD (NUC188) domain EF-1_beta_acid PF10587.9 KRH92820.1 - 0.19 12.2 5.1 0.32 11.5 4.6 1.7 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region U1snRNP70_N PF12220.8 KRH92820.1 - 0.31 11.7 7.1 0.46 11.2 7.1 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ArfGap PF01412.18 KRH92821.1 - 9e-12 45.1 2.7 9e-12 45.1 2.7 2.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.6 KRH92821.1 - 0.025 14.4 3.1 0.042 13.7 3.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BSP_II PF05432.11 KRH92821.1 - 2.7 7.6 9.4 0.24 11.0 4.7 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) IF4E PF01652.18 KRH92823.1 - 2.2e-36 125.1 0.5 2.6e-36 124.8 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1132 PF06575.12 KRH92823.1 - 0.075 13.4 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) PI31_Prot_C PF08577.11 KRH92824.1 - 0.01 17.0 0.2 0.021 16.0 0.2 1.6 1 1 0 1 1 1 0 PI31 proteasome regulator Sulfate_transp PF00916.20 KRH92825.1 - 7.2e-08 31.6 13.6 7.2e-08 31.6 13.6 1.7 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KRH92825.1 - 0.001 18.7 0.2 0.018 14.7 0.0 2.2 2 0 0 2 2 2 1 STAS domain DUF5445 PF17520.2 KRH92825.1 - 0.075 12.9 0.8 0.34 10.8 0.8 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5445) GCS2 PF04107.13 KRH92825.1 - 0.12 11.7 0.2 9.1 5.5 0.3 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) dCMP_cyt_deam_1 PF00383.23 KRH92826.1 - 4.5e-18 65.0 1.7 3.1e-17 62.3 1.7 1.9 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KRH92826.1 - 2.3e-13 50.0 1.7 3.5e-13 49.5 1.7 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Tub PF01167.18 KRH92827.1 - 5.4e-16 59.1 0.4 6.1e-16 58.9 0.4 1.0 1 0 0 1 1 1 1 Tub family ArfGap PF01412.18 KRH92829.1 - 7.3e-28 97.0 0.7 7.3e-28 97.0 0.7 2.3 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf VitD-bind_III PF09164.10 KRH92829.1 - 0.013 15.5 0.3 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 Vitamin D binding protein, domain III YtxH PF12732.7 KRH92829.1 - 0.36 11.4 3.9 21 5.7 1.0 2.6 2 1 0 2 2 2 0 YtxH-like protein CHASE6_C PF17150.4 KRH92829.1 - 0.49 11.1 4.2 0.89 10.3 0.6 2.6 1 1 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Membralin PF09746.9 KRH92829.1 - 0.85 8.6 7.3 1.2 8.1 7.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein zf-RING_9 PF13901.6 KRH92829.1 - 1.5 8.8 8.0 0.062 13.3 2.0 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon ABC2_membrane_3 PF12698.7 KRH92829.1 - 2.9 6.9 9.4 3.7 6.6 9.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein EMC3_TMCO1 PF01956.16 KRH92829.1 - 4.5 7.0 6.1 1.7 8.3 3.1 1.8 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like rve PF00665.26 KRH92830.1 - 8.6e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92830.1 - 0.00053 20.0 0.9 0.00091 19.3 0.9 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 KRH92830.1 - 0.066 13.4 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 DDE domain Ribosomal_L19e PF01280.20 KRH92832.1 - 1.3e-47 161.5 4.6 1.5e-47 161.3 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e SIKE PF05769.11 KRH92832.1 - 0.0083 16.1 1.5 0.014 15.3 1.5 1.3 1 0 0 1 1 1 1 SIKE family Cpn60_TCP1 PF00118.24 KRH92833.1 - 2.6e-122 408.9 1.3 3.6e-122 408.5 1.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DDE_Tnp_IS1595 PF12762.7 KRH92834.1 - 5e-15 55.8 0.0 6.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.6 KRH92834.1 - 0.0008 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.6 KRH92834.1 - 0.00085 19.1 0.1 0.0012 18.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Beta-TrCP_D PF12125.8 KRH92834.1 - 0.002 18.0 3.6 0.49 10.3 0.4 2.3 2 0 0 2 2 2 2 D domain of beta-TrCP zf-CCHC PF00098.23 KRH92836.1 - 3e-06 27.0 1.8 4.5e-06 26.5 1.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH92836.1 - 0.043 13.5 2.0 0.093 12.5 1.6 1.8 1 1 0 1 1 1 0 Zinc knuckle G-gamma PF00631.22 KRH92836.1 - 0.15 12.0 0.8 0.43 10.6 0.8 1.8 1 0 0 1 1 1 0 GGL domain TFIIE_beta PF02186.15 KRH92836.1 - 0.32 11.3 4.1 0.15 12.4 1.5 1.8 2 0 0 2 2 2 0 TFIIE beta subunit core domain Transposase_mut PF00872.18 KRH92839.1 - 1.6e-05 23.9 0.8 1.9e-05 23.7 0.8 1.0 1 0 0 1 1 1 1 Transposase, Mutator family CrgA PF06781.12 KRH92841.1 - 0.77 9.9 0.0 0.77 9.9 0.0 2.9 3 0 0 3 3 3 0 Cell division protein CrgA DUF1283 PF06932.11 KRH92844.1 - 0.0024 18.0 0.1 0.003 17.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) ubiquitin PF00240.23 KRH92845.1 - 0.042 13.6 2.5 0.099 12.4 2.5 1.7 1 0 0 1 1 1 0 Ubiquitin family IF4E PF01652.18 KRH92846.1 - 3.7e-29 101.6 0.6 4.5e-29 101.3 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E V-ATPase_H_C PF11698.8 KRH92847.1 - 1.5e-22 79.9 0.2 1.1e-21 77.2 0.1 2.6 2 0 0 2 2 2 1 V-ATPase subunit H REV1_C PF16727.5 KRH92847.1 - 0.18 12.2 0.5 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain dUTPase PF00692.19 KRH92849.1 - 1.1e-07 31.6 0.1 1.6e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 dUTPase PMM PF03332.13 KRH92850.1 - 3.3e-78 262.5 0.9 2.2e-66 223.8 0.3 2.2 2 0 0 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KRH92850.1 - 0.0016 18.2 0.1 0.0016 18.2 0.1 3.2 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF444 PF04285.12 KRH92850.1 - 0.0048 16.0 2.9 0.0085 15.2 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF444) S6PP PF05116.13 KRH92850.1 - 0.0052 16.4 0.0 0.36 10.3 0.0 2.6 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase DNA_topoisoIV PF00521.20 KRH92851.1 - 4.5e-109 365.2 15.0 6.5e-87 292.2 0.8 2.1 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KRH92851.1 - 4.6e-42 143.3 1.1 4.6e-42 143.3 1.1 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM Thioredoxin PF00085.20 KRH92853.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF4366 PF14283.6 KRH92854.1 - 0.00081 19.5 1.5 0.00085 19.4 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Zip PF02535.22 KRH92854.1 - 0.012 14.9 0.4 0.013 14.7 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.13 KRH92854.1 - 0.016 15.5 0.6 0.018 15.3 0.6 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RNA_pol_Rpc4 PF05132.14 KRH92854.1 - 0.018 15.5 1.7 0.018 15.4 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 KRH92854.1 - 0.023 14.4 0.4 0.024 14.4 0.4 1.1 1 0 0 1 1 1 0 Connexin DUF4519 PF15012.6 KRH92854.1 - 0.036 14.2 2.3 0.036 14.2 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4834 PF16118.5 KRH92854.1 - 0.037 15.0 1.1 0.049 14.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 KRH92854.1 - 0.04 13.6 0.8 0.049 13.3 0.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 KRH92854.1 - 0.047 12.7 1.5 0.052 12.5 1.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MAP17 PF15807.5 KRH92854.1 - 0.051 13.8 1.8 0.063 13.5 1.8 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ureide_permease PF07168.11 KRH92854.1 - 0.053 12.3 1.7 0.061 12.1 1.7 1.0 1 0 0 1 1 1 0 Ureide permease Sec62 PF03839.16 KRH92854.1 - 0.072 12.6 1.9 0.088 12.3 1.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RPN2_C PF18004.1 KRH92854.1 - 0.081 12.8 10.0 0.1 12.5 10.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2370 PF10176.9 KRH92854.1 - 0.098 12.3 0.2 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PPL5 PF18168.1 KRH92854.1 - 0.12 11.6 3.4 0.14 11.4 3.4 1.0 1 0 0 1 1 1 0 Prim-pol family 5 O-antigen_lig PF13425.6 KRH92854.1 - 0.12 11.1 2.7 0.14 10.9 2.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 KRH92854.1 - 0.13 11.3 0.8 0.14 11.2 0.8 1.0 1 0 0 1 1 1 0 CLN3 protein Claudin_2 PF13903.6 KRH92854.1 - 0.15 11.8 1.4 0.16 11.7 0.1 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Coilin_N PF15862.5 KRH92854.1 - 0.46 10.3 9.9 0.54 10.1 9.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF3464 PF11947.8 KRH92854.1 - 0.99 9.1 4.3 1.4 8.6 4.3 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 KRH92854.1 - 1.1 7.9 7.1 1.3 7.8 7.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ETRAMP PF09716.10 KRH92854.1 - 1.6 8.8 13.0 13 5.9 13.0 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 KRH92854.1 - 1.7 9.0 11.0 0.27 11.5 5.2 2.2 1 1 1 2 2 2 0 Orf78 (ac78) T4BSS_DotI_IcmL PF11393.8 KRH92855.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component MFS_1_like PF12832.7 KRH92855.1 - 0.35 9.7 17.3 4.3 6.1 17.3 2.4 1 1 0 1 1 1 0 MFS_1 like family EMP24_GP25L PF01105.24 KRH92858.1 - 0.032 14.2 2.3 0.042 13.8 2.3 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF5318 PF17249.2 KRH92858.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5318) HTH_Tnp_Tc3_2 PF01498.18 KRH92859.1 - 2.8e-13 49.9 0.8 9.6e-13 48.2 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.6 KRH92859.1 - 0.0033 17.2 0.2 0.82 9.5 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 KRH92859.1 - 0.012 15.6 0.1 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_33 PF13592.6 KRH92859.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix MarR_2 PF12802.7 KRH92859.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 MarR family 3HCDH PF00725.22 KRH92859.1 - 0.047 14.3 0.1 0.092 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain HTH_23 PF13384.6 KRH92859.1 - 0.048 13.5 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 KRH92859.1 - 0.051 13.1 0.2 0.8 9.3 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_49 PF18010.1 KRH92859.1 - 0.063 13.1 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain TrmB PF01978.19 KRH92859.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_AlpA PF05930.12 KRH92859.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Tnp_Tc3_1 PF11427.8 KRH92859.1 - 0.14 12.0 0.2 17 5.3 0.0 2.6 2 1 0 2 2 2 0 Tc3 transposase TAF1D PF15333.6 KRH92859.1 - 0.19 11.5 5.1 0.23 11.2 4.7 1.3 1 1 0 1 1 1 0 TATA box-binding protein-associated factor 1D YgaB PF14182.6 KRH92859.1 - 0.41 11.1 4.5 4.8 7.7 0.1 3.0 2 1 1 3 3 3 0 YgaB-like protein TBD PF12845.7 KRH92860.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 TBD domain Noc2 PF03715.13 KRH92861.1 - 2.1e-11 43.6 1.3 2.1e-11 43.6 1.3 1.9 2 0 0 2 2 2 1 Noc2p family Choline_kinase PF01633.20 KRH92862.1 - 2.6e-13 50.1 3.1 2.1e-11 43.8 3.1 2.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KRH92862.1 - 1.3e-07 31.8 0.0 2.3e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1 PF00133.22 KRH92864.1 - 5.2e-51 173.6 0.0 8.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KRH92864.1 - 1.1e-23 83.9 2.0 2.5e-23 82.7 2.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KRH92864.1 - 6e-05 22.5 0.4 0.00076 18.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain BRICHOS PF04089.14 KRH92864.1 - 0.05 13.9 0.4 0.29 11.4 0.1 2.2 2 0 0 2 2 2 0 BRICHOS domain Acyltransferase PF01553.21 KRH92866.1 - 2.1e-17 63.0 0.1 5.2e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KRH92866.1 - 0.047 13.8 0.7 0.15 12.2 0.7 1.9 1 0 0 1 1 1 0 Acyltransferase C-terminus RT_RNaseH PF17917.1 KRH92867.1 - 5.5e-26 90.9 0.0 1.2e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92867.1 - 2e-24 85.5 0.0 5.4e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92867.1 - 1.1e-23 84.0 0.8 2.6e-23 82.7 0.8 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH92867.1 - 1.3e-18 67.3 0.0 4.6e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92867.1 - 6.6e-12 45.4 0.4 1.3e-10 41.2 0.7 2.7 2 0 0 2 2 2 1 Integrase zinc binding domain DUF1476 PF07345.11 KRH92867.1 - 0.024 15.0 1.3 0.054 13.9 0.2 2.2 3 0 0 3 3 3 0 ATPase inhibitor subunit zeta zf-H2C2 PF09337.10 KRH92867.1 - 0.072 13.3 1.2 6.2 7.1 0.2 3.1 3 0 0 3 3 3 0 H2C2 zinc finger RVT_2 PF07727.14 KRH92867.1 - 0.084 12.5 0.3 0.39 10.3 0.0 2.2 2 1 1 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) TbpB_C PF17483.2 KRH92870.1 - 0.019 15.3 0.6 0.04 14.3 0.6 1.6 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B RRM_1 PF00076.22 KRH92870.1 - 0.036 13.9 0.3 0.13 12.1 0.2 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1749 PF08538.10 KRH92871.1 - 1.5e-25 90.0 0.0 1.8e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) LCAT PF02450.15 KRH92871.1 - 0.0035 16.6 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 KRH92871.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 KRH92871.1 - 0.051 13.2 0.0 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KRH92871.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KRH92871.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CTV_P13 PF06922.11 KRH92872.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein RVT_1 PF00078.27 KRH92874.1 - 7.1e-22 78.0 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ferritin PF00210.24 KRH92874.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Ferritin-like domain DDE_1 PF03184.19 KRH92875.1 - 7.7e-19 68.0 0.0 9e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sacchrp_dh_NADP PF03435.18 KRH92876.1 - 4.9e-13 49.5 0.1 8.1e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KRH92876.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KRH92876.1 - 0.038 14.4 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.26 KRH92877.1 - 0.033 14.4 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain DUF1758 PF05585.12 KRH92877.1 - 0.056 13.2 0.1 0.062 13.1 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) rve PF00665.26 KRH92879.1 - 1.5e-13 50.9 0.0 2.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-U11-48K PF05253.12 KRH92880.1 - 0.16 11.9 6.8 65 3.6 0.1 4.6 3 2 4 7 7 7 0 U11-48K-like CHHC zinc finger PGM_PMM_I PF02878.16 KRH92882.1 - 9.7e-17 61.0 0.0 1.5e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KRH92882.1 - 3.9e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Yae1_N PF09811.9 KRH92882.1 - 0.048 13.4 6.3 0.095 12.4 6.3 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal PGM_PMM_II PF02879.16 KRH92882.1 - 0.062 13.9 0.0 3.1 8.5 0.0 3.4 3 1 1 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SET PF00856.28 KRH92883.1 - 1.1e-15 58.4 0.9 1.1e-15 58.4 0.9 3.6 2 2 0 2 2 2 1 SET domain DAO PF01266.24 KRH92885.1 - 1.1e-45 156.7 0.0 1.6e-45 156.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KRH92885.1 - 1.1e-31 109.4 0.0 2.3e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KRH92885.1 - 2.1e-06 27.1 2.5 0.0046 16.1 2.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KRH92885.1 - 0.00036 19.9 0.7 0.0018 17.6 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRH92885.1 - 0.0041 16.3 1.6 0.039 13.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KRH92885.1 - 0.005 16.3 1.2 0.007 15.8 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF4130 PF13566.6 KRH92885.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 NAD_binding_8 PF13450.6 KRH92885.1 - 0.12 12.7 1.0 2 8.7 0.2 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ribosomal_L40e PF01020.17 KRH92886.1 - 3.6e-14 52.4 10.7 5.3e-14 51.8 10.7 1.2 1 0 0 1 1 1 1 Ribosomal L40e family UPF0547 PF10571.9 KRH92886.1 - 0.16 12.1 1.3 0.22 11.6 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DHHC PF01529.20 KRH92886.1 - 3.3 7.8 6.0 1 9.5 3.2 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase tRNA-synt_2 PF00152.20 KRH92887.1 - 1.6e-24 86.6 0.1 2.2e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KRH92887.1 - 6.4e-11 42.1 0.1 9.9e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_1 PF00133.22 KRH92888.1 - 2.6e-13 49.1 0.2 4.5e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KRH92888.1 - 1.9e-08 33.5 0.0 4.5e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) GCD14 PF08704.10 KRH92889.1 - 5.6e-23 81.9 0.2 1.2e-21 77.5 0.0 2.5 2 1 1 3 3 3 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 KRH92889.1 - 0.0011 18.1 0.2 0.024 13.7 0.0 2.3 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 KRH92889.1 - 0.0043 16.9 0.0 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRH92889.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KRH92889.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KRH92889.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD_2 PF06733.15 KRH92890.1 - 9.2e-34 116.6 12.7 9.6e-33 113.3 12.7 2.6 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KRH92890.1 - 4.3e-05 23.4 0.0 0.0014 18.5 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KRH92890.1 - 0.032 14.5 0.5 5.4 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KRH92890.1 - 0.064 12.7 0.2 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein Sec1 PF00995.23 KRH92891.1 - 1.1e-38 133.8 24.8 1.5e-38 133.4 24.8 1.1 1 0 0 1 1 1 1 Sec1 family bZIP_1 PF00170.21 KRH92892.1 - 0.13 12.4 5.9 0.56 10.4 0.3 3.5 3 0 0 3 3 3 0 bZIP transcription factor LIN52 PF10044.9 KRH92892.1 - 9.5 7.0 7.9 5.6 7.7 0.3 3.7 3 1 1 4 4 4 0 Retinal tissue protein CBM49 PF09478.10 KRH92893.1 - 0.079 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 EMC3_TMCO1 PF01956.16 KRH92894.1 - 0.014 15.2 0.4 0.03 14.1 0.4 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Tudor_RapA PF18337.1 KRH92896.1 - 0.068 13.4 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain zf-CCHC PF00098.23 KRH92897.1 - 9.6e-06 25.4 2.1 1.6e-05 24.7 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH92897.1 - 0.037 13.8 2.7 0.095 12.4 2.6 1.8 1 1 0 1 1 1 0 Zinc knuckle zf-HC5HC2H PF13771.6 KRH92897.1 - 0.045 14.0 0.3 0.069 13.4 0.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain RVT_1 PF00078.27 KRH92898.1 - 5.9e-06 25.9 0.0 6.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.14 KRH92898.1 - 0.1 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 PRELI-like family DUF3806 PF12713.7 KRH92898.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) RVT_1 PF00078.27 KRH92899.1 - 9.9e-10 38.3 0.5 1e-09 38.2 0.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA_synthFbeta PF17759.1 KRH92900.1 - 3.6e-27 95.2 0.1 6.6e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KRH92900.1 - 7.5e-16 58.1 1.0 3.9e-15 55.8 0.3 2.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KRH92900.1 - 1.1e-06 28.8 0.3 1.5e-05 25.2 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetase B5 domain ALS_ss_C PF10369.9 KRH92900.1 - 0.054 13.7 0.2 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Small subunit of acetolactate synthase Pkinase PF00069.25 KRH92901.1 - 1.5e-65 221.2 3.2 6.2e-65 219.2 3.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92901.1 - 2.6e-39 135.1 0.2 3.7e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH92901.1 - 7.5e-12 45.1 0.1 1.1e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KRH92901.1 - 0.0007 19.0 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KRH92901.1 - 0.013 14.3 0.2 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase HEAT_2 PF13646.6 KRH92902.1 - 0.0026 18.1 0.0 0.063 13.7 0.0 3.0 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KRH92902.1 - 0.0075 16.4 0.1 0.23 11.8 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 KRH92902.1 - 0.064 13.3 5.8 0.063 13.3 0.8 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UN_NPL4 PF11543.8 KRH92905.1 - 0.01 16.3 0.1 0.041 14.4 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 KRH92907.1 - 1.3e-96 324.1 23.8 9.5e-49 166.1 16.8 2.6 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KRH92907.1 - 4.9e-09 35.5 1.3 4.2e-06 25.8 0.1 3.3 3 0 0 3 3 3 2 MreB/Mbl protein Vfa1 PF08432.10 KRH92907.1 - 0.33 11.3 19.0 0.42 10.9 5.5 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DDE_Tnp_IS1595 PF12762.7 KRH92909.1 - 5.6e-25 88.1 0.0 8.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH92909.1 - 0.00031 20.3 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family HlyIII PF03006.20 KRH92911.1 - 0.22 11.2 12.9 0.77 9.4 3.2 2.2 2 0 0 2 2 2 0 Haemolysin-III related EFP_N PF08207.12 KRH92913.1 - 9.4e-07 28.8 1.4 1.7e-06 28.0 1.4 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain AAA PF00004.29 KRH92915.1 - 7.9e-16 58.7 2.0 1.2e-15 58.1 0.3 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KRH92915.1 - 1.9e-14 53.8 2.1 3e-09 36.8 0.3 2.6 2 1 1 3 3 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KRH92915.1 - 1.8e-11 44.3 0.5 2.3e-09 37.5 0.0 2.6 2 1 0 2 2 2 1 Replication factor C C-terminal domain RuvB_N PF05496.12 KRH92915.1 - 5.7e-10 39.2 0.1 1.5e-09 37.8 0.1 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KRH92915.1 - 1.4e-09 38.2 1.2 6.6e-09 36.0 1.2 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KRH92915.1 - 2.9e-06 27.8 0.1 8.7e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KRH92915.1 - 3.1e-06 27.3 3.1 6.7e-06 26.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KRH92915.1 - 3.2e-06 27.4 0.2 0.0001 22.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KRH92915.1 - 5.2e-06 26.5 0.8 0.00012 22.0 0.3 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KRH92915.1 - 8.2e-06 25.7 0.1 2.6e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KRH92915.1 - 1.3e-05 25.7 0.9 7.9e-05 23.2 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KRH92915.1 - 5.2e-05 23.2 0.9 0.00036 20.4 0.9 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KRH92915.1 - 7.8e-05 22.2 0.0 0.00095 18.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KRH92915.1 - 9.9e-05 22.5 0.2 0.00042 20.5 0.1 2.1 1 1 1 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta PF06144.13 KRH92915.1 - 0.0001 22.1 2.5 0.00021 21.1 2.5 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 KRH92915.1 - 0.00013 21.9 0.2 0.00039 20.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KRH92915.1 - 0.00014 22.2 0.1 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA C-terminal domain AAA_7 PF12775.7 KRH92915.1 - 0.00015 21.3 0.1 0.00033 20.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KRH92915.1 - 0.00016 21.4 0.1 0.0097 15.6 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.15 KRH92915.1 - 0.00017 21.5 2.1 0.011 15.7 0.1 2.5 1 1 1 2 2 2 1 NTPase ATPase_2 PF01637.18 KRH92915.1 - 0.0002 21.3 2.6 0.0003 20.8 1.8 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KRH92915.1 - 0.00025 20.8 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KRH92915.1 - 0.00047 19.3 0.1 0.0009 18.4 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KRH92915.1 - 0.00048 20.5 0.1 0.0028 18.0 0.0 2.2 1 1 1 2 2 2 1 RNA helicase AAA_30 PF13604.6 KRH92915.1 - 0.0005 19.8 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KRH92915.1 - 0.00056 19.7 0.2 0.0013 18.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KRH92915.1 - 0.00089 19.6 0.8 0.0041 17.4 0.8 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KRH92915.1 - 0.00098 19.2 0.5 0.0087 16.1 0.2 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 KRH92915.1 - 0.0017 17.8 0.1 0.36 10.2 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein DEAD PF00270.29 KRH92915.1 - 0.0017 18.1 0.8 0.1 12.3 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KRH92915.1 - 0.0018 17.7 0.6 0.5 9.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 KRH92915.1 - 0.0023 17.1 0.4 0.0065 15.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) KTI12 PF08433.10 KRH92915.1 - 0.0029 17.1 0.0 0.0077 15.7 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TIP49 PF06068.13 KRH92915.1 - 0.0032 16.7 0.2 0.0058 15.9 0.1 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain APS_kinase PF01583.20 KRH92915.1 - 0.0037 17.2 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 KRH92915.1 - 0.0042 16.4 0.0 0.0085 15.4 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin Torsin PF06309.11 KRH92915.1 - 0.0069 16.5 0.0 0.029 14.5 0.0 2.0 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.6 KRH92915.1 - 0.011 15.9 0.1 0.025 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KRH92915.1 - 0.012 15.8 0.3 0.086 13.0 0.0 2.3 2 2 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KRH92915.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRH92915.1 - 0.017 15.7 2.1 0.035 14.6 1.9 1.9 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KRH92915.1 - 0.019 14.9 1.0 0.032 14.2 0.1 1.9 2 1 1 3 3 1 0 RsgA GTPase NACHT PF05729.12 KRH92915.1 - 0.019 14.9 0.1 0.79 9.6 0.0 2.8 3 1 1 4 4 3 0 NACHT domain Thymidylate_kin PF02223.17 KRH92915.1 - 0.023 14.4 0.3 0.066 12.9 0.1 2.0 1 1 1 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 KRH92915.1 - 0.026 13.7 0.0 0.085 12.0 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 KRH92915.1 - 0.043 13.4 0.1 0.096 12.3 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KRH92915.1 - 0.05 13.2 0.4 1.7 8.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 KRH92915.1 - 0.05 13.3 0.0 0.57 9.9 0.0 2.2 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.9 KRH92915.1 - 0.052 12.8 0.1 0.25 10.5 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KRH92915.1 - 0.054 13.5 0.3 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KRH92915.1 - 0.059 13.1 0.8 9.2 6.0 0.3 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KRH92915.1 - 0.064 13.7 0.6 0.21 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 KRH92915.1 - 0.2 11.7 2.2 1.3 9.1 2.2 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cupin_8 PF13621.6 KRH92916.1 - 0.47 10.1 8.7 1.7 8.3 7.5 2.3 2 1 0 2 2 2 0 Cupin-like domain MS_channel PF00924.18 KRH92918.1 - 4.7e-15 55.7 5.2 4.7e-15 55.7 5.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF4342 PF14242.6 KRH92918.1 - 0.048 13.7 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF3675 PF12428.8 KRH92918.1 - 5.8 7.5 0.0 5.8 7.5 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3675) TFIIA PF03153.13 KRH92920.1 - 1.8e-13 51.3 5.5 1.1e-12 48.7 0.3 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit ATP-synt_C PF00137.21 KRH92921.1 - 2e-09 37.7 14.2 9.8e-05 22.6 0.7 2.2 2 0 0 2 2 2 2 ATP synthase subunit C STAS PF01740.21 KRH92922.1 - 0.0094 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain AAA_19 PF13245.6 KRH92922.1 - 0.012 15.9 0.1 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MAPEG PF01124.18 KRH92922.1 - 0.048 13.6 0.3 0.048 13.6 0.3 2.4 2 0 0 2 2 2 0 MAPEG family GATA PF00320.27 KRH92923.1 - 9.5e-25 85.9 20.2 2.5e-15 55.8 6.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KRH92923.1 - 0.018 14.6 7.7 0.27 10.8 0.8 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 KRH92923.1 - 0.09 12.8 8.3 7.6 6.7 8.3 2.7 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KRH92923.1 - 0.68 10.1 5.8 4.3 7.5 0.2 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Elf1 PF05129.13 KRH92923.1 - 1.2 9.2 6.0 1.3 9.1 0.2 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L32p PF01783.23 KRH92923.1 - 4.5 7.6 7.3 84 3.5 0.0 3.2 2 1 0 2 2 2 0 Ribosomal L32p protein family zf-piccolo PF05715.13 KRH92923.1 - 5.5 7.2 10.1 4.8 7.4 1.2 3.4 2 2 1 3 3 3 0 Piccolo Zn-finger Hexapep PF00132.24 KRH92924.1 - 0.11 12.3 4.4 0.057 13.2 1.2 2.3 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Hira PF07569.11 KRH92924.1 - 0.47 10.1 5.6 0.16 11.7 0.4 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split RVT_1 PF00078.27 KRH92925.1 - 5.5e-31 107.8 0.5 1.2e-30 106.7 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KRH92925.1 - 6.9e-08 32.7 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 KRH92925.1 - 1.4e-06 28.2 0.2 6.7e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_A2B PF12384.8 KRH92925.1 - 0.033 13.7 0.1 0.072 12.6 0.1 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase Retrotrans_gag PF03732.17 KRH92925.1 - 0.26 11.6 1.7 0.43 10.9 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Ribonuc_2-5A PF06479.12 KRH92926.1 - 1.9e-33 115.3 2.1 2.4e-33 115.0 0.5 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KRH92926.1 - 8.3e-16 58.1 5.8 1.1e-13 51.2 2.2 2.6 2 1 0 2 2 2 2 Protein kinase domain MutL_C PF08676.11 KRH92929.1 - 3e-06 27.1 0.8 0.0059 16.4 0.2 3.1 2 1 0 2 2 2 2 MutL C terminal dimerisation domain DndB PF14072.6 KRH92929.1 - 0.038 13.2 0.1 0.071 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA-sulfur modification-associated Lactamase_B PF00753.27 KRH92930.1 - 2.3e-09 37.5 0.4 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KRH92930.1 - 0.0011 19.4 2.6 0.0025 18.3 2.6 1.6 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KRH92930.1 - 0.018 14.5 0.3 0.028 13.9 0.3 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain zf-CCCH_3 PF15663.5 KRH92931.1 - 1.4e-10 41.3 22.6 0.00081 19.6 7.7 3.5 1 1 3 4 4 4 3 Zinc-finger containing family zf-CCCH PF00642.24 KRH92931.1 - 6.7e-10 38.6 44.3 0.0011 18.9 0.5 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KRH92931.1 - 1.6e-06 28.8 33.4 0.0019 18.8 0.4 5.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_2 PF14608.6 KRH92931.1 - 2.6e-05 24.5 48.2 0.19 12.2 9.8 5.6 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KRH92931.1 - 8.1e-05 22.5 4.0 8.1e-05 22.5 4.0 6.7 6 1 0 6 6 6 3 Zinc finger domain zf-CCCH_4 PF18044.1 KRH92931.1 - 0.012 15.4 2.7 0.012 15.4 2.7 5.7 5 2 0 5 5 5 0 CCCH-type zinc finger DUF4905 PF16248.5 KRH92931.1 - 0.051 13.5 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4905) zf-C3H1 PF10650.9 KRH92931.1 - 2.1 8.2 17.6 4 7.2 0.4 4.6 4 0 0 4 4 4 0 Putative zinc-finger domain Chromo PF00385.24 KRH92932.1 - 1.4e-17 63.3 1.8 3.5e-17 62.1 1.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KRH92932.1 - 2.5e-06 27.5 9.3 4.9e-06 26.5 0.5 2.6 3 0 0 3 3 3 2 Chromo shadow domain Mtf2_C PF14061.6 KRH92932.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 WD40 PF00400.32 KRH92935.1 - 4.6e-17 62.1 3.3 0.00072 20.3 0.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 KRH92935.1 - 2.5e-05 23.8 1.6 2.5e-05 23.8 1.6 4.1 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 KRH92935.1 - 0.00089 18.0 2.8 0.0069 15.1 0.9 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KRH92935.1 - 0.0067 16.9 2.3 2.5 8.7 0.0 4.2 3 1 1 4 4 4 1 PQQ-like domain RAB3GAP2_N PF14655.6 KRH92935.1 - 0.0084 15.4 0.2 0.31 10.3 0.1 2.6 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TPR_1 PF00515.28 KRH92935.1 - 0.12 12.3 6.5 0.19 11.6 0.5 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KRH92935.1 - 0.37 11.0 7.0 0.23 11.7 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat YmzC PF14157.6 KRH92935.1 - 1 9.5 4.5 4.8 7.3 0.1 3.9 3 0 0 3 3 3 0 YmzC-like protein SWIM PF04434.17 KRH92936.1 - 2.1e-06 27.2 0.1 4.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger GDA1_CD39 PF01150.17 KRH92937.1 - 6.7e-09 34.9 12.4 0.00044 19.0 1.0 3.3 2 2 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Hep_core_N PF08290.11 KRH92937.1 - 0.3 11.1 0.3 5.1e+02 0.8 0.0 4.5 5 0 0 5 5 5 0 Hepatitis core protein, putative zinc finger Nucleoporin_FG PF13634.6 KRH92938.1 - 4.6e-09 37.0 209.4 3.1e-05 24.7 31.7 7.4 2 2 5 7 7 7 5 Nucleoporin FG repeat region ERAP1_C PF11838.8 KRH92939.1 - 1.3e-22 80.8 1.2 2.6e-22 79.8 1.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KRH92939.1 - 6.7e-16 58.5 0.1 1.9e-15 57.0 0.1 1.8 1 0 0 1 1 1 1 Peptidase family M1 domain PHA_synth_III_E PF09712.10 KRH92939.1 - 0.062 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) OmdA PF13376.6 KRH92939.1 - 0.12 12.4 0.1 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated rve PF00665.26 KRH92940.1 - 3.2e-14 53.1 0.0 9.6e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH92940.1 - 0.0001 22.3 0.2 0.00032 20.7 0.2 1.8 1 1 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH92940.1 - 0.0035 17.6 0.2 0.0098 16.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-HC2 PF13490.6 KRH92940.1 - 0.052 13.8 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative zinc-finger PepSY_like PF11396.8 KRH92940.1 - 3.4 8.3 11.1 0.29 11.7 2.1 3.0 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like DEAD PF00270.29 KRH92943.1 - 2.3e-14 53.5 1.3 1.1e-11 44.8 0.6 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH92943.1 - 2.6e-10 40.6 7.5 2.6e-10 40.6 7.5 3.5 3 1 0 4 4 4 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KRH92943.1 - 0.0095 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KRH92943.1 - 0.13 12.6 1.0 2.7 8.3 0.0 3.1 3 1 0 3 3 3 0 AAA domain MFS_1_like PF12832.7 KRH92945.1 - 4e-29 101.6 36.0 3.3e-28 98.6 36.0 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KRH92945.1 - 1.3e-15 57.3 18.0 8.5e-13 47.9 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.27 KRH92946.1 - 7.7e-28 97.5 0.1 1.7e-27 96.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KRH92946.1 - 4e-06 27.3 0.2 2.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH92946.1 - 7.8e-06 26.5 0.1 5.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 KRH92946.1 - 1.2e-05 25.1 1.8 2.8e-05 24.0 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 KRH92946.1 - 1.4e-05 25.3 0.0 4.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.8 KRH92946.1 - 0.024 15.1 0.4 0.024 15.1 0.4 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G PET10 PF17316.2 KRH92946.1 - 0.039 13.5 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 DUF1356 PF07092.12 KRH92946.1 - 0.065 12.5 0.6 0.23 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) Asp_protease PF09668.10 KRH92946.1 - 0.093 12.5 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF5090 PF17009.5 KRH92947.1 - 3.6e-46 157.5 7.6 4e-46 157.3 7.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) CmcI PF04989.12 KRH92947.1 - 0.057 13.1 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase DNA_primase_lrg PF04104.14 KRH92948.1 - 3.4e-33 115.2 6.0 4.6e-33 114.7 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF4649 PF15507.6 KRH92948.1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) VP9 PF09625.10 KRH92948.1 - 0.1 12.8 0.6 0.53 10.5 0.2 2.4 2 0 0 2 2 2 0 VP9 protein RVT_1 PF00078.27 KRH92950.1 - 2.7e-30 105.5 0.1 4.1e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTR PF12789.7 KRH92951.1 - 0.027 14.5 0.6 0.066 13.3 0.6 1.7 1 0 0 1 1 1 0 Phage tail repeat like OAD_gamma PF04277.13 KRH92952.1 - 0.021 15.4 0.0 0.022 15.4 0.0 1.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TssO PF17561.2 KRH92952.1 - 0.058 13.5 1.2 0.056 13.6 1.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO tRNA-synt_2b PF00587.25 KRH92955.1 - 7.5e-22 78.1 0.5 3e-21 76.2 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KRH92955.1 - 5.9e-08 32.9 17.4 1.3e-06 28.6 17.4 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 KRH92955.1 - 0.35 10.2 4.4 0.16 11.3 2.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 KRH92955.1 - 0.43 10.6 8.3 0.99 9.4 8.3 1.6 1 0 0 1 1 1 0 FlxA-like protein FAM76 PF16046.5 KRH92955.1 - 0.49 9.7 6.2 0.92 8.8 6.2 1.4 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 KRH92955.1 - 3 7.9 15.0 3 7.9 10.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.25 KRH92956.1 - 1.3e-33 116.5 13.4 1.6e-18 67.0 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH92956.1 - 5.2e-17 62.0 0.1 1.2e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1041 PF06292.17 KRH92957.1 - 0.079 13.4 0.2 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) AAA_22 PF13401.6 KRH92958.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KRH92958.1 - 0.00011 22.5 0.0 0.00024 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH92958.1 - 0.00022 21.6 0.0 0.00033 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KRH92958.1 - 0.0011 18.3 0.1 0.0022 17.2 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.18 KRH92958.1 - 0.0012 18.6 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KRH92958.1 - 0.0035 17.3 0.7 0.0051 16.8 0.7 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KRH92958.1 - 0.0061 17.1 0.1 0.01 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain TK PF00265.18 KRH92958.1 - 0.0061 16.4 0.2 0.0099 15.8 0.2 1.3 1 0 0 1 1 1 1 Thymidine kinase NACHT PF05729.12 KRH92958.1 - 0.0076 16.2 0.6 0.085 12.8 0.6 2.2 1 1 0 1 1 1 1 NACHT domain ATPase PF06745.13 KRH92958.1 - 0.0078 15.6 0.4 0.013 14.9 0.4 1.4 1 1 0 1 1 1 1 KaiC Microtub_bd PF16796.5 KRH92958.1 - 0.0085 16.0 0.6 0.016 15.2 0.1 1.7 2 0 0 2 2 2 1 Microtubule binding DUF2075 PF09848.9 KRH92958.1 - 0.01 15.1 0.1 0.026 13.8 0.2 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KRH92958.1 - 0.011 15.7 1.6 0.52 10.4 1.6 2.2 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KRH92958.1 - 0.025 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KRH92958.1 - 0.027 14.2 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KRH92958.1 - 0.034 14.5 0.2 0.29 11.6 0.0 2.1 1 1 1 2 2 2 0 RNA helicase AAA_30 PF13604.6 KRH92958.1 - 0.038 13.7 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain GvpD PF07088.11 KRH92958.1 - 0.049 12.2 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_11 PF13086.6 KRH92958.1 - 0.12 12.1 2.4 0.23 11.2 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KRH92958.1 - 0.28 11.6 1.5 1.6 9.2 1.5 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DASH_Ask1 PF08655.10 KRH92959.1 - 0.043 13.7 0.3 3.7 7.5 0.1 2.4 1 1 1 2 2 2 0 DASH complex subunit Ask1 ApoB100_C PF12491.8 KRH92959.1 - 0.24 11.4 1.9 8.4 6.4 0.2 2.3 1 1 1 2 2 2 0 Apolipoprotein B100 C terminal PCNA_N PF00705.18 KRH92960.1 - 8.3e-21 74.0 0.7 2.1e-20 72.7 0.7 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KRH92960.1 - 1.5e-19 70.4 3.5 3.3e-17 62.9 0.3 2.3 2 1 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KRH92960.1 - 2.5e-05 23.9 0.4 4.1e-05 23.2 0.4 1.5 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 KRH92960.1 - 0.028 13.5 0.3 3.4 6.7 0.2 2.2 1 1 1 2 2 2 0 Hus1-like protein RRM_1 PF00076.22 KRH92961.1 - 9.8e-47 156.7 5.2 5.9e-16 58.1 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KRH92961.1 - 1.7e-07 31.1 0.1 0.031 14.3 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KRH92961.1 - 2.8e-05 24.0 3.7 0.086 12.8 0.1 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KRH92961.1 - 5.5e-05 23.2 0.2 1.4 9.1 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 KRH92961.1 - 0.0059 16.6 2.9 3.3 7.8 0.0 3.6 4 0 0 4 4 4 2 RNA binding domain PABP PF00658.18 KRH92961.1 - 0.04 14.1 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.8 KRH92961.1 - 0.07 13.2 0.6 3.9 7.6 0.0 3.3 3 1 0 3 3 3 0 Limkain b1 Helicase_C_2 PF13307.6 KRH92962.1 - 1.4e-37 129.5 1.4 6.6e-36 124.1 1.4 2.2 1 1 0 1 1 1 1 Helicase C-terminal domain Helicase_C PF00271.31 KRH92962.1 - 0.0022 18.3 0.1 0.0063 16.8 0.1 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CAP PF00188.26 KRH92964.1 - 1.5e-05 25.8 0.3 9.9e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CsgF PF10614.9 KRH92964.1 - 0.59 10.4 5.6 0.73 10.1 1.7 3.1 1 1 1 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein DUF2877 PF11392.8 KRH92964.1 - 2 9.2 3.8 25 5.7 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Syja_N PF02383.18 KRH92965.1 - 6.3e-23 81.6 5.3 6.3e-23 81.6 5.3 2.8 2 1 0 2 2 2 1 SacI homology domain Protamine_P2 PF00841.19 KRH92965.1 - 0.049 14.1 0.9 18 5.9 0.0 2.6 2 0 0 2 2 2 0 Sperm histone P2 AP3D1 PF06375.11 KRH92966.1 - 0.00049 20.4 0.1 0.00049 20.4 0.1 2.7 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 rve PF00665.26 KRH92967.1 - 3e-19 69.3 0.0 5.1e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH92967.1 - 0.00028 20.6 0.0 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 KRH92967.1 - 0.0025 18.0 0.6 0.0044 17.3 0.6 1.4 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.6 KRH92967.1 - 0.045 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Ribonuc_red_sm PF00268.21 KRH92970.1 - 3.8e-108 361.2 10.8 3.8e-108 361.2 10.8 1.4 2 0 0 2 2 2 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KRH92970.1 - 1.2 10.0 0.0 1.2 10.0 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4744) RVT_1 PF00078.27 KRH92971.1 - 7.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KRH92971.1 - 0.033 14.9 0.1 0.091 13.5 0.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RT_RNaseH PF17917.1 KRH92972.1 - 1.2e-30 105.9 0.0 3.6e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH92972.1 - 6.6e-29 99.9 0.0 2e-28 98.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH92972.1 - 5.8e-26 91.4 0.4 1.5e-25 90.0 0.4 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH92972.1 - 9.8e-05 22.3 1.6 0.00023 21.1 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 KRH92972.1 - 0.00047 20.8 0.0 0.0009 19.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KRH92972.1 - 0.0017 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 KRH92972.1 - 0.0029 18.2 0.0 0.006 17.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Scytalone_dh PF02982.14 KRH92972.1 - 0.076 12.8 0.1 0.86 9.4 0.1 2.5 2 0 0 2 2 2 0 Scytalone dehydratase UCH PF00443.29 KRH92973.1 - 5.3 6.5 15.7 0.19 11.2 3.1 2.8 2 2 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S3Ae PF01015.18 KRH92974.1 - 3.1e-47 160.8 11.1 3.8e-47 160.5 11.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family RL11D PF11088.8 KRH92976.1 - 0.048 14.0 0.8 4.4 7.7 0.1 2.2 1 1 1 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 PLDc_N PF13396.6 KRH92976.1 - 0.059 13.3 0.3 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal GPI-anchored PF10342.9 KRH92976.1 - 0.076 13.8 0.5 0.26 12.1 0.5 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD99L2 PF12301.8 KRH92977.1 - 0.012 15.9 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 PAP_PilO PF06864.12 KRH92977.1 - 0.061 12.2 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF2621 PF11084.8 KRH92977.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Ferric_reduct PF01794.19 KRH92977.1 - 0.072 13.2 0.1 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Ferric reductase like transmembrane component MscS_TM PF12794.7 KRH92977.1 - 0.13 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 tRNA-synt_2b PF00587.25 KRH92979.1 - 1.6e-19 70.5 0.0 4.7e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KRH92979.1 - 7.7e-14 51.6 2.2 2.2e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain DHOase PF12890.7 KRH92979.1 - 0.0094 15.9 0.6 0.3 11.0 0.1 2.2 2 0 0 2 2 2 1 Dihydro-orotase-like SAC3 PF12209.8 KRH92979.1 - 0.047 13.9 0.1 0.38 11.0 0.1 2.5 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain IMS PF00817.20 KRH92979.1 - 0.07 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family XRN1_D1 PF18332.1 KRH92979.1 - 0.22 11.3 3.4 0.51 10.1 3.4 1.5 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain Plant_all_beta PF10532.9 KRH92980.1 - 0.0012 19.1 0.8 0.0018 18.6 0.8 1.2 1 0 0 1 1 1 1 Plant specific N-all beta domain Ribosomal_L5_C PF00673.21 KRH92981.1 - 4.5e-20 71.6 0.2 6.9e-20 71.0 0.2 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KRH92981.1 - 5.3e-15 55.5 0.2 1.1e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 MCM PF00493.23 KRH92983.1 - 4.3e-88 294.2 0.0 9.3e-88 293.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH92983.1 - 4e-21 75.2 0.2 9.1e-21 74.0 0.2 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRH92983.1 - 2.7e-19 69.4 3.5 9.4e-19 67.6 3.5 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KRH92983.1 - 3.6e-09 36.3 0.1 1.3e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRH92983.1 - 5.3e-06 26.5 0.1 2.8e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KRH92983.1 - 0.00026 20.7 0.5 0.0055 16.4 0.0 3.1 3 1 0 3 3 3 1 Sigma-54 interaction domain MCM_N PF14551.6 KRH92983.1 - 0.00032 21.2 0.3 0.0011 19.5 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 KRH92983.1 - 0.0034 17.3 0.0 0.012 15.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KRH92983.1 - 0.078 12.7 0.1 0.38 10.5 0.1 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TAP42 PF04177.12 KRH92984.1 - 0.00013 21.2 0.8 0.00032 20.0 0.8 1.5 1 0 0 1 1 1 1 TAP42-like family Hist_deacetyl PF00850.19 KRH92985.1 - 9.6e-26 91.0 0.1 2.6e-25 89.6 0.0 1.7 1 1 1 2 2 2 1 Histone deacetylase domain DUF1103 PF06513.11 KRH92985.1 - 0.0039 16.8 9.7 0.0057 16.3 9.7 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Herpes_UL49_1 PF03117.14 KRH92985.1 - 0.027 13.7 0.2 0.036 13.4 0.2 1.2 1 0 0 1 1 1 0 UL49 family NIL PF09383.10 KRH92985.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NIL domain AvrM-A PF18241.1 KRH92985.1 - 0.079 13.4 5.2 0.11 12.9 4.6 1.5 1 1 0 1 1 1 0 Flax-rust effector AvrM-A DUF637 PF04830.13 KRH92985.1 - 0.18 11.6 3.1 0.8 9.5 3.1 1.9 1 1 0 1 1 1 0 Possible hemagglutinin (DUF637) CelTOS PF18659.1 KRH92985.1 - 0.86 10.1 10.2 2.5 8.6 10.2 1.9 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Tox-HDC PF15656.6 KRH92985.1 - 2.2 8.5 12.2 2.5 8.3 3.6 2.2 1 1 1 2 2 2 0 Toxin with a H, D/N and C signature PNPase PF03726.14 KRH92985.1 - 3.1 8.4 7.2 29 5.3 6.5 2.6 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Phe_tRNA-synt_N PF02912.18 KRH92986.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain SPOB_ab PF14682.6 KRH92986.1 - 0.44 10.6 8.2 0.27 11.3 0.6 2.7 3 0 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal RNF220 PF15926.5 KRH92987.1 - 0.04 13.5 0.2 0.04 13.5 0.2 2.8 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 MBD_C PF14048.6 KRH92988.1 - 0.0013 19.4 1.2 0.0061 17.2 0.1 2.4 2 1 1 3 3 3 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF2207 PF09972.9 KRH92988.1 - 0.0023 16.8 2.0 0.0023 16.8 2.0 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) NOG1_N PF17835.1 KRH92988.1 - 0.046 13.7 0.6 0.046 13.7 0.6 3.0 2 2 0 2 2 2 0 NOG1 N-terminal helical domain DUF5588 PF17826.1 KRH92988.1 - 0.066 12.1 5.3 0.099 11.5 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) 2OG-Fe_Oxy_2 PF10014.9 KRH92988.1 - 0.11 12.3 1.6 0.17 11.7 0.3 1.8 1 1 1 2 2 2 0 2OG-Fe dioxygenase Katanin_con80 PF13925.6 KRH92988.1 - 0.18 11.8 8.0 0.22 11.6 0.3 3.0 2 1 1 3 3 3 0 con80 domain of Katanin DUF4806 PF16064.5 KRH92988.1 - 0.25 11.6 8.2 0.8 10.0 0.1 3.8 2 2 1 4 4 4 0 Domain of unknown function (DUF4806) PCRF PF03462.18 KRH92988.1 - 0.57 10.0 15.3 0.14 12.0 0.8 2.9 2 1 1 3 3 3 0 PCRF domain IL3 PF02059.15 KRH92988.1 - 0.83 9.7 11.2 0.48 10.5 6.6 2.7 1 1 1 2 2 2 0 Interleukin-3 DUF2203 PF09969.9 KRH92988.1 - 4.7 8.0 11.1 12 6.6 0.7 2.7 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_C48 PF02902.19 KRH92989.1 - 3.3e-25 89.2 1.0 5.9e-25 88.4 1.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sec20 PF03908.13 KRH92990.1 - 3.5e-05 23.6 0.5 4.2e-05 23.4 0.5 1.1 1 0 0 1 1 1 1 Sec20 DUF5089 PF17002.5 KRH92990.1 - 0.00043 20.2 0.2 0.0005 20.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 KRH92990.1 - 0.011 16.0 0.3 0.014 15.6 0.3 1.2 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus ETRAMP PF09716.10 KRH92990.1 - 0.063 13.4 2.1 0.083 13.0 2.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.11 KRH92990.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Synaptobrevin PF00957.21 KRH92990.1 - 4.2 7.2 8.4 12 5.8 8.4 1.7 1 1 0 1 1 1 0 Synaptobrevin SbcD_C PF12320.8 KRH92991.1 - 0.088 13.1 0.2 0.098 13.0 0.2 1.1 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Phosphodiest PF01663.22 KRH92993.1 - 2.7e-06 27.2 0.2 0.00024 20.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KRH92993.1 - 0.0051 16.2 0.4 0.0097 15.3 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 KRH92993.1 - 0.038 13.4 0.1 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 Sulfatase Ribosomal_L5e PF17144.4 KRH92994.1 - 7.4e-48 162.6 4.5 7.4e-47 159.4 1.2 2.1 2 0 0 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KRH92994.1 - 4.4e-14 53.2 5.3 4.4e-14 53.2 5.3 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region CCM2_C PF16545.5 KRH92994.1 - 0.0081 16.7 4.3 0.016 15.7 0.2 2.7 2 1 1 3 3 3 1 Cerebral cavernous malformation protein, harmonin-homology Ribosomal_L18p PF00861.22 KRH92994.1 - 0.024 15.0 1.3 0.034 14.5 0.3 1.7 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RRM_1 PF00076.22 KRH92995.1 - 0.0083 15.9 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KRH92995.1 - 0.092 12.7 0.0 0.096 12.6 0.0 1.1 1 0 0 1 1 1 0 RL domain RRM_1 PF00076.22 KRH92996.1 - 8.8e-07 28.7 0.0 0.0009 19.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTPA PF03095.15 KRH92997.1 - 7.4e-47 160.3 0.7 6.8e-38 130.8 0.0 1.9 2 0 0 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein HisK_N PF09385.10 KRH92997.1 - 0.061 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Histidine kinase N terminal DUF3432 PF11914.8 KRH92997.1 - 0.13 12.5 16.9 4.1 7.7 16.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) POP1 PF06978.11 KRH92999.1 - 8.1e-10 39.0 9.3 3.6e-05 23.9 3.5 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Pkinase PF00069.25 KRH93000.1 - 6.7e-39 133.8 0.3 9.9e-39 133.3 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93000.1 - 5.5e-25 88.1 0.1 7.4e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KRH93000.1 - 7.2e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KRH93000.1 - 0.00064 18.6 0.5 0.00079 18.3 0.5 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KRH93000.1 - 0.012 15.3 0.3 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KRH93000.1 - 0.034 14.1 0.1 0.37 10.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0449 PF15136.6 KRH93001.1 - 1.5 9.3 6.4 0.35 11.4 2.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3941 PF13081.6 KRH93001.1 - 5.2 7.6 7.8 23 5.6 1.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3941) DUF5353 PF17304.2 KRH93005.1 - 0.039 13.7 1.1 4.7 7.0 0.1 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5353) Fer4_5 PF12801.7 KRH93005.1 - 0.066 13.2 2.3 0.066 13.2 2.3 4.8 6 1 0 6 6 6 0 4Fe-4S binding domain DUF373 PF04123.13 KRH93005.1 - 3.2 7.1 19.9 4 6.8 19.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_3_6 PF07332.11 KRH93006.1 - 9.8 6.3 10.9 2.6 8.1 0.5 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III UCH PF00443.29 KRH93007.1 - 7.3e-31 107.6 20.5 7.3e-31 107.6 20.5 2.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KRH93007.1 - 4.1e-10 39.8 29.0 4.1e-10 39.8 29.0 3.1 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KRH93007.1 - 0.00035 20.8 11.9 0.00059 20.1 0.3 3.7 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.21 KRH93007.1 - 0.004 17.2 2.7 0.004 17.2 2.7 4.3 3 1 0 3 3 3 1 FYVE zinc finger BIR PF00653.21 KRH93007.1 - 0.27 11.9 0.1 0.27 11.9 0.1 3.6 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Zip PF02535.22 KRH93007.1 - 2.2 7.4 12.1 0.063 12.5 5.7 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter HAD_2 PF13419.6 KRH93008.1 - 2.1e-14 54.0 2.4 2.1e-14 54.0 2.4 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KRH93008.1 - 0.011 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_like PF13242.6 KRH93009.1 - 0.067 13.3 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1653 PF07866.11 KRH93011.1 - 0.0065 16.8 0.1 1.8 8.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1653) DUF903 PF06004.12 KRH93011.1 - 0.013 15.4 0.1 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) DUF768 PF05589.11 KRH93011.1 - 0.12 12.4 0.5 1.6 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF768) Forkhead PF00250.18 KRH93012.1 - 6.3e-18 64.8 0.3 1.9e-17 63.3 0.3 1.8 1 0 0 1 1 1 1 Forkhead domain SMC_hinge PF06470.13 KRH93013.1 - 1.8e-24 86.3 0.1 5.3e-24 84.8 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 KRH93013.1 - 3.9e-12 46.1 47.4 2.2e-10 40.4 47.4 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KRH93013.1 - 1.6e-10 41.3 43.1 1.6e-10 41.3 43.1 3.5 1 1 2 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KRH93013.1 - 6.1e-09 35.5 0.1 1.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KRH93013.1 - 8.4e-09 35.7 0.1 8.4e-09 35.7 0.1 3.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KRH93013.1 - 0.00014 22.4 0.2 0.00014 22.4 0.2 4.2 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 KRH93013.1 - 4.6 7.7 121.0 0.013 16.0 72.1 5.3 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KRH93014.1 - 5.7e-25 88.4 0.5 5.7e-25 88.4 0.5 2.4 4 0 0 4 4 4 1 ABC transporter ABC_membrane PF00664.23 KRH93014.1 - 9.8e-14 51.6 21.8 5.3e-13 49.3 21.8 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KRH93014.1 - 1.4e-11 44.3 5.8 3.2e-11 43.1 5.8 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KRH93014.1 - 0.00057 19.7 25.3 0.00057 19.7 25.3 3.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KRH93014.1 - 0.0012 18.7 1.9 0.0012 18.7 1.9 2.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KRH93014.1 - 0.052 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KRH93014.1 - 0.052 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Asp5 PF17000.5 KRH93015.1 - 0.049 13.8 2.1 0.07 13.3 2.1 1.2 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 RT_RNaseH PF17917.1 KRH93018.1 - 4.4e-30 104.1 0.0 1.1e-29 102.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93018.1 - 2.4e-27 95.9 0.1 4.6e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93018.1 - 2.5e-27 94.8 0.0 6.1e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93018.1 - 8.2e-21 74.4 0.0 1.5e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93018.1 - 1.5e-06 28.2 0.2 3.4e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 KRH93018.1 - 0.0027 17.5 0.3 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase thumb domain gag_pre-integrs PF13976.6 KRH93018.1 - 0.013 15.4 0.1 0.051 13.4 0.1 2.1 1 0 0 1 1 1 0 GAG-pre-integrase domain RT_RNaseH PF17917.1 KRH93020.1 - 8.9e-29 99.9 0.0 1.9e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93020.1 - 1.5e-26 93.3 0.2 2.8e-26 92.4 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93020.1 - 3.5e-26 91.2 0.0 7.7e-26 90.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KRH93020.1 - 2.7e-09 37.4 0.0 7.6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH93020.1 - 2.4e-06 28.1 0.0 4.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH93020.1 - 1.4e-05 24.9 0.8 2.8e-05 23.9 0.8 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_thumb PF06817.14 KRH93020.1 - 2.5e-05 24.0 0.1 7.5e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Asp_protease PF09668.10 KRH93020.1 - 0.036 13.8 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 KRH93021.1 - 8.9e-21 74.3 0.0 9.6e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF4203 PF13886.6 KRH93023.1 - 1.1e-05 25.2 30.6 9.5e-05 22.2 30.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2198 PF09964.9 KRH93023.1 - 0.024 14.7 4.7 0.024 14.7 4.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DWNN PF08783.11 KRH93025.1 - 1.5e-18 66.8 0.1 3.2e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KRH93025.1 - 7.7e-11 41.6 7.3 7.7e-11 41.6 7.3 3.3 4 0 0 4 4 4 1 Zinc knuckle zf-C3HC4_4 PF15227.6 KRH93025.1 - 0.00022 21.3 10.0 0.00022 21.3 10.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KRH93025.1 - 0.00037 20.5 7.5 0.001 19.0 7.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCHC PF00098.23 KRH93025.1 - 0.0034 17.4 2.6 0.0034 17.4 2.6 2.3 3 0 0 3 3 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 KRH93025.1 - 0.0037 17.1 9.1 0.0037 17.1 9.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH93025.1 - 0.0042 16.9 7.5 0.0042 16.9 7.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KRH93025.1 - 0.0047 16.8 3.7 0.01 15.7 3.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KRH93025.1 - 0.021 14.9 5.9 0.021 14.9 5.9 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Ribosomal_S4e PF00900.20 KRH93025.1 - 0.066 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomal family S4e zf-C3HC4_2 PF13923.6 KRH93025.1 - 2.1 8.3 18.3 0.24 11.3 11.0 2.7 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRH93025.1 - 6.1 6.8 12.4 0.57 10.1 6.0 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DnaJ PF00226.31 KRH93026.1 - 2.6e-15 56.3 1.1 4.6e-15 55.5 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF960 PF06124.11 KRH93026.1 - 0.21 12.2 1.8 0.24 12.1 0.5 1.7 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) HAD_2 PF13419.6 KRH93027.1 - 4.5e-09 36.6 0.8 4.5e-09 36.6 0.8 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KRH93027.1 - 5.3e-05 23.6 0.0 0.013 15.8 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase NIF PF03031.18 KRH93027.1 - 0.0082 15.9 0.8 0.089 12.6 0.8 2.3 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 KRH93027.1 - 0.028 14.3 0.0 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Acid Phosphatase DUF2608 PF11019.8 KRH93027.1 - 0.065 12.7 5.3 0.48 9.9 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2608) AAA PF00004.29 KRH93028.1 - 3.8e-45 153.5 0.1 9.8e-45 152.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH93028.1 - 4.8e-12 45.5 0.0 1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KRH93028.1 - 9.4e-10 38.9 0.0 3e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KRH93028.1 - 2.6e-07 31.2 0.0 0.00022 21.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KRH93028.1 - 6.2e-07 29.5 0.1 3.9e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KRH93028.1 - 9.2e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 KRH93028.1 - 1.4e-05 24.9 0.3 3.2e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KRH93028.1 - 2.4e-05 24.6 0.5 0.016 15.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.13 KRH93028.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KRH93028.1 - 0.0019 18.7 0.1 0.012 16.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KRH93028.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KRH93028.1 - 0.0025 17.4 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KRH93028.1 - 0.003 17.0 0.1 0.008 15.6 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KRH93028.1 - 0.0044 16.4 0.2 0.032 13.6 0.0 2.2 1 1 0 2 2 2 1 KaiC TsaE PF02367.17 KRH93028.1 - 0.0046 17.0 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KRH93028.1 - 0.0048 16.0 0.9 0.0064 15.6 0.0 1.6 2 0 0 2 2 1 1 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KRH93028.1 - 0.006 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KRH93028.1 - 0.007 16.2 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KRH93028.1 - 0.012 14.8 0.0 0.031 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KRH93028.1 - 0.017 15.5 0.0 0.052 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KRH93028.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KRH93028.1 - 0.019 14.4 0.1 0.048 13.1 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KRH93028.1 - 0.019 15.2 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KRH93028.1 - 0.021 14.5 0.0 0.091 12.5 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KRH93028.1 - 0.024 14.5 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 KRH93028.1 - 0.033 13.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KRH93028.1 - 0.036 13.3 0.1 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin CPT PF07931.12 KRH93028.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KRH93028.1 - 0.061 13.5 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRH93028.1 - 0.074 12.8 0.1 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KRH93028.1 - 0.081 13.3 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRH93028.1 - 0.18 12.3 1.2 0.36 11.3 0.0 2.2 2 1 0 2 2 1 0 ABC transporter AAA_11 PF13086.6 KRH93028.1 - 0.38 10.5 6.9 0.84 9.4 3.6 2.8 2 1 0 2 2 2 0 AAA domain SelK_SelG PF10961.8 KRH93029.1 - 1.6 9.4 2.9 1.9 9.2 2.9 1.3 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Skp1_POZ PF03931.15 KRH93030.1 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain gag-asp_proteas PF13975.6 KRH93032.1 - 0.037 14.6 0.0 0.048 14.2 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 KRH93033.1 - 5.2e-09 36.3 0.2 6.7e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Methyltransf_32 PF13679.6 KRH93033.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.6 KRH93033.1 - 0.15 12.5 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sin3_corepress PF08295.12 KRH93035.1 - 1e-13 51.2 0.6 1e-13 51.2 0.6 3.6 3 2 1 4 4 4 1 Sin3 family co-repressor PAH PF02671.21 KRH93035.1 - 0.00034 20.7 3.6 0.18 11.9 0.0 3.6 3 0 0 3 3 3 2 Paired amphipathic helix repeat Lsr2 PF11774.8 KRH93035.1 - 0.032 14.4 0.6 0.15 12.2 0.6 2.1 1 0 0 1 1 1 0 Lsr2 DUF4734 PF15881.5 KRH93035.1 - 0.068 13.3 1.9 0.58 10.3 1.9 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) CRAM_rpt PF07016.11 KRH93035.1 - 0.17 11.7 4.7 0.23 11.3 0.3 2.5 1 1 1 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor tRNA_int_endo PF01974.17 KRH93037.1 - 1e-08 35.1 0.1 1.5e-07 31.4 0.1 2.2 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3537 PF12056.8 KRH93037.1 - 0.65 8.8 2.9 0.86 8.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Homeodomain PF00046.29 KRH93038.1 - 6.7e-16 57.9 5.1 6.7e-16 57.9 5.1 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KRH93038.1 - 0.00086 19.2 0.8 0.00086 19.2 0.8 1.9 1 1 1 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 KRH93038.1 - 0.047 13.5 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain RRM_1 PF00076.22 KRH93040.1 - 1.9e-37 126.9 6.2 1.2e-14 53.8 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KRH93040.1 - 0.00035 20.5 0.2 0.94 9.5 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KRH93040.1 - 0.00077 19.5 0.2 0.59 10.3 0.0 3.7 2 1 1 3 3 3 2 Limkain b1 RRM_2 PF04059.12 KRH93040.1 - 3.8 7.8 6.8 3.3 8.0 0.1 3.5 3 0 0 3 3 3 0 RNA recognition motif 2 Vasculin PF15337.6 KRH93041.1 - 0.033 15.0 0.0 0.035 14.9 0.0 1.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 MLVIN_C PF18697.1 KRH93043.1 - 0.034 14.2 0.1 0.062 13.4 0.0 1.5 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Tubulin PF00091.25 KRH93046.1 - 2.2e-68 230.3 0.0 3.3e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KRH93046.1 - 3.8e-49 166.1 0.6 5.8e-49 165.4 0.6 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KRH93046.1 - 0.02 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Misat_Tub_SegII PF10644.9 KRH93046.1 - 0.073 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain GBP_repeat PF02526.14 KRH93047.1 - 0.16 11.7 0.3 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Glycophorin-binding protein Hemopexin PF00045.19 KRH93048.1 - 0.47 10.4 5.4 6.8 6.7 0.2 2.3 2 0 0 2 2 2 0 Hemopexin RIO1 PF01163.22 KRH93051.1 - 1.3e-29 103.2 3.3 2.4e-29 102.3 3.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KRH93051.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rio2_N PF09202.11 KRH93051.1 - 0.00027 21.1 0.6 0.00074 19.7 0.5 1.8 1 1 0 1 1 1 1 Rio2, N-terminal Pkinase PF00069.25 KRH93051.1 - 0.00071 19.0 2.2 0.0015 17.9 2.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KRH93051.1 - 0.00072 19.0 0.2 0.0037 16.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5344 PF17279.2 KRH93052.1 - 0.021 15.4 0.9 0.026 15.1 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DASH_Dam1 PF08653.10 KRH93052.1 - 0.08 12.7 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF2573 PF10835.8 KRH93052.1 - 0.098 13.0 2.4 0.24 11.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) GLE1 PF07817.13 KRH93053.1 - 0.00059 19.1 1.9 0.66 9.1 0.0 2.5 2 1 0 2 2 2 2 GLE1-like protein CdvA PF18822.1 KRH93053.1 - 0.16 11.8 6.4 0.43 10.4 1.4 2.4 2 0 0 2 2 2 0 CdvA-like coiled-coil domain WD40 PF00400.32 KRH93054.1 - 1.2e-08 35.4 8.2 0.0035 18.2 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 KRH93054.1 - 2.1e-05 24.0 5.8 0.00036 19.9 0.9 2.7 2 1 0 2 2 2 2 WD40-like domain NUP214 PF16755.5 KRH93054.1 - 0.00022 20.6 0.1 0.00033 20.0 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 SHMT PF00464.19 KRH93055.1 - 1.9e-74 250.6 0.1 3.6e-74 249.7 0.1 1.4 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KRH93055.1 - 5.1e-06 25.9 0.0 7.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DHquinase_II PF01220.19 KRH93055.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Dehydroquinase class II DEAD PF00270.29 KRH93056.1 - 3.8e-37 127.8 0.6 1.1e-36 126.2 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH93056.1 - 4.5e-30 104.2 0.7 3.5e-28 98.2 0.1 2.9 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93056.1 - 0.0041 17.1 0.6 0.019 15.0 0.6 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KRH93056.1 - 0.21 11.9 1.5 0.92 9.8 1.5 2.2 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.14 KRH93058.1 - 0.00022 19.7 0.0 0.00035 19.0 0.0 1.2 1 0 0 1 1 1 1 CDC45-like protein SapB_1 PF05184.15 KRH93058.1 - 0.0098 15.9 3.2 0.0098 15.9 3.2 2.3 2 0 0 2 2 2 1 Saposin-like type B, region 1 YceD PF02620.17 KRH93058.1 - 0.082 13.0 1.8 0.17 12.0 1.8 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD Fer2 PF00111.27 KRH93059.1 - 3.6e-12 46.1 0.1 4.6e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Methyltransf_23 PF13489.6 KRH93060.1 - 2.3e-11 43.8 0.0 2.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRH93060.1 - 4.9e-09 36.8 0.0 9.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRH93060.1 - 3.7e-08 34.0 0.0 9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRH93060.1 - 1e-06 29.3 0.0 2.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH93060.1 - 6.1e-05 22.8 0.3 7.5e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KRH93060.1 - 0.00053 19.5 0.5 0.0079 15.7 0.1 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 KRH93060.1 - 0.0065 16.0 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain VirArc_Nuclease PF12187.8 KRH93060.1 - 0.016 14.8 1.2 0.016 14.8 1.2 1.6 1 1 0 2 2 2 0 Viral/Archaeal nuclease DUF1870 PF08965.10 KRH93060.1 - 0.017 15.1 0.5 0.031 14.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) adh_short PF00106.25 KRH93062.1 - 2.7e-09 36.8 0.0 9.1e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KRH93062.1 - 2.8e-09 36.8 0.0 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KRH93062.1 - 0.004 17.6 0.0 0.0077 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding RmlD_sub_bind PF04321.17 KRH93062.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 KRH93062.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 KRH93062.1 - 0.026 13.9 0.1 0.077 12.4 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_31 PF13847.6 KRH93062.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.10 KRH93062.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 KR domain ApbA PF02558.16 KRH93062.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RVT_1 PF00078.27 KRH93064.1 - 1.3e-22 80.4 0.1 1.7e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PixA PF12306.8 KRH93064.1 - 0.22 11.7 0.2 0.22 11.7 0.2 2.0 2 1 0 2 2 2 0 Inclusion body protein G6PD_N PF00479.22 KRH93065.1 - 2.3e-09 38.1 1.0 0.00012 22.8 0.4 2.4 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 KRH93065.1 - 2.1e-05 23.9 0.9 0.00037 19.8 0.1 2.6 1 1 1 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain GFO_IDH_MocA PF01408.22 KRH93065.1 - 0.11 13.4 0.0 0.2 12.5 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Arf PF00025.21 KRH93066.1 - 9.1e-44 149.0 0.0 1e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KRH93066.1 - 1.8e-13 50.8 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KRH93066.1 - 1.7e-11 44.0 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KRH93066.1 - 1.6e-09 37.4 0.6 6.1e-06 25.6 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KRH93066.1 - 3.8e-06 26.5 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KRH93066.1 - 5.7e-06 25.8 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRH93066.1 - 5.9e-05 23.1 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KRH93066.1 - 0.0038 16.5 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Vpu PF00558.19 KRH93068.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Vpu protein rve PF00665.26 KRH93071.1 - 4.5e-08 33.3 0.2 1.9e-07 31.3 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KRH93071.1 - 0.00032 20.4 0.1 0.00077 19.2 0.1 1.8 1 1 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KRH93071.1 - 0.0023 18.0 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain UCH_1 PF13423.6 KRH93071.1 - 0.0032 17.1 0.9 0.0037 16.9 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNA_pol_Rpb1_1 PF04997.12 KRH93071.1 - 0.014 14.8 0.8 0.017 14.4 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 BIR PF00653.21 KRH93072.1 - 0.059 14.0 0.1 0.068 13.8 0.1 1.1 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Ribosomal_L34e PF01199.18 KRH93075.1 - 1.7e-26 92.3 3.8 1.8e-26 92.2 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e PI3_PI4_kinase PF00454.27 KRH93079.1 - 3.6e-10 40.1 2.6 5.4e-10 39.5 2.6 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Dpoe2NT PF12213.8 KRH93079.1 - 0.56 10.5 3.8 12 6.3 0.0 3.1 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal MMR_HSR1_Xtn PF16897.5 KRH93080.1 - 1.3e-28 99.1 1.4 1.3e-28 99.1 1.4 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KRH93080.1 - 1.7e-21 76.4 0.3 5.7e-21 74.7 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KRH93080.1 - 4.7e-20 71.4 0.1 8.2e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KRH93080.1 - 9.4e-14 51.2 2.1 1.3e-11 44.2 0.1 3.1 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KRH93080.1 - 6.2e-05 23.1 0.2 0.23 11.5 0.0 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KRH93080.1 - 0.00024 20.7 0.2 0.39 10.2 0.0 3.4 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KRH93080.1 - 0.0019 18.1 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KRH93080.1 - 0.012 15.0 0.2 0.028 13.9 0.2 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 KRH93080.1 - 0.012 14.6 0.0 0.034 13.1 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 KRH93080.1 - 0.038 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KRH93080.1 - 0.04 13.4 0.7 2 7.8 0.1 3.0 1 1 1 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KRH93080.1 - 0.056 13.7 0.0 1.2 9.3 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase YchF-GTPase_C PF06071.13 KRH93080.1 - 0.085 13.1 0.1 2.9 8.1 0.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF933) ATP_bind_1 PF03029.17 KRH93080.1 - 0.37 10.5 1.9 19 4.9 0.1 2.7 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein RNase_PH PF01138.21 KRH93082.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 SQHop_cyclase_N PF13249.6 KRH93082.1 - 0.14 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain Elf1 PF05129.13 KRH93083.1 - 1.8e-22 79.1 1.5 2.1e-22 79.0 1.5 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KRH93083.1 - 0.00063 20.2 0.3 0.00077 19.9 0.3 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-LITAF-like PF10601.9 KRH93083.1 - 0.016 15.5 2.4 0.055 13.7 2.6 1.6 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KRH93083.1 - 0.03 14.4 0.7 0.049 13.8 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KRH93083.1 - 0.043 13.7 1.2 0.058 13.3 1.2 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.6 KRH93083.1 - 0.13 12.2 2.1 0.27 11.2 2.2 1.6 1 1 0 1 1 1 0 zinc-ribbon domain XPG_I PF00867.18 KRH93084.1 - 1.2e-13 51.2 4.3 8e-13 48.6 0.1 3.5 4 1 0 4 4 4 1 XPG I-region HHH PF00633.23 KRH93084.1 - 0.034 14.0 1.1 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif TrwC PF08751.11 KRH93084.1 - 0.035 13.6 0.2 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 TrwC relaxase HTH_55 PF18622.1 KRH93084.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 RctB helix turn helix domain FOP_dimer PF09398.10 KRH93084.1 - 0.67 10.3 5.1 0.26 11.5 0.3 2.9 2 1 0 2 2 2 0 FOP N terminal dimerisation domain 5_3_exonuc PF01367.20 KRH93084.1 - 1.1 9.9 3.8 1.1 9.9 0.8 2.6 2 2 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sec7 PF01369.20 KRH93085.1 - 2.3e-28 99.2 19.3 2.3e-28 99.1 6.3 3.4 3 1 1 4 4 4 2 Sec7 domain HEAT_2 PF13646.6 KRH93088.1 - 5e-08 33.2 0.0 0.00074 19.9 0.0 2.9 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KRH93088.1 - 6.4e-06 26.0 0.2 3 8.4 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 KRH93088.1 - 0.0058 16.7 0.2 0.66 10.0 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 PC_rep PF01851.22 KRH93088.1 - 0.073 13.5 2.0 2.9 8.5 0.1 3.8 3 0 0 3 3 3 0 Proteasome/cyclosome repeat RICTOR_V PF14668.6 KRH93088.1 - 0.11 12.7 1.8 2.1 8.6 0.1 3.3 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF2462 PF09495.10 KRH93089.1 - 0.033 14.9 1.4 0.042 14.6 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) PIN_11 PF18479.1 KRH93090.1 - 0.033 14.3 0.2 0.092 12.9 0.2 1.7 1 0 0 1 1 1 0 PIN like domain tRNA-synt_2 PF00152.20 KRH93092.1 - 1.2e-71 241.3 1.8 1.7e-71 240.9 1.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KRH93092.1 - 1.1e-06 28.5 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KRH93092.1 - 0.00084 18.9 0.8 0.15 11.5 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RecJ_OB PF17768.1 KRH93092.1 - 0.11 12.8 0.3 3.2 8.0 0.1 2.6 2 0 0 2 2 2 0 RecJ OB domain Oxidored_q2 PF00420.24 KRH93093.1 - 0.057 13.1 0.3 0.083 12.5 0.3 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L zf-C2H2 PF00096.26 KRH93096.1 - 1.2e-05 25.4 12.2 0.0084 16.5 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRH93096.1 - 0.00021 21.8 8.1 0.2 12.6 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KRH93096.1 - 0.00036 20.8 2.8 0.00036 20.8 2.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KRH93096.1 - 0.026 14.8 2.9 0.11 12.8 2.8 2.1 1 1 0 1 1 1 0 C2H2-type zinc ribbon Acyltransf_C PF16076.5 KRH93096.1 - 0.14 12.3 2.6 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Acyltransferase C-terminus ParA PF10609.9 KRH93097.1 - 3.2e-07 30.0 0.2 1.4e-06 28.0 0.2 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AARP2CN PF08142.12 KRH93098.1 - 1.3e-05 25.2 0.1 0.0003 20.8 0.0 3.4 2 1 0 2 2 2 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 KRH93098.1 - 5.1e-05 22.8 0.1 5.1e-05 22.8 0.1 3.2 2 2 1 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PLA2G12 PF06951.11 KRH93098.1 - 0.093 12.6 1.5 0.23 11.3 1.5 1.6 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF3942 PF13078.6 KRH93100.1 - 0.061 13.6 0.2 0.07 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) zf-CCHC PF00098.23 KRH93101.1 - 3.6e-06 26.8 1.1 5e-06 26.3 1.1 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KRH93101.1 - 0.014 15.0 0.6 0.022 14.5 0.6 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KRH93101.1 - 0.054 13.5 1.7 0.089 12.8 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KRH93101.1 - 0.15 12.0 1.2 0.15 12.0 1.2 1.5 2 0 0 2 2 2 0 Zinc knuckle TFIID-18kDa PF02269.16 KRH93103.1 - 3.3e-21 75.1 1.5 4e-21 74.8 1.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Cas_Cmr5 PF09701.10 KRH93103.1 - 0.042 14.1 0.2 0.049 13.9 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) SRP54 PF00448.22 KRH93105.1 - 4.4e-66 222.2 0.1 4.4e-66 222.2 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KRH93105.1 - 1.4e-23 83.3 2.2 2.7e-23 82.5 0.2 2.6 1 1 1 2 2 2 1 Signal peptide binding domain cobW PF02492.19 KRH93105.1 - 1.6e-05 24.5 1.0 0.00016 21.3 1.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54_N PF02881.19 KRH93105.1 - 7.8e-05 22.8 6.8 7.8e-05 22.8 6.8 2.9 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KRH93105.1 - 0.0046 16.7 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3819 PF12842.7 KRH93105.1 - 0.007 16.3 0.8 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Parathyroid PF01279.17 KRH93105.1 - 0.014 16.0 2.2 0.028 15.0 2.2 1.4 1 0 0 1 1 1 0 Parathyroid hormone family MobB PF03205.14 KRH93105.1 - 0.018 14.9 1.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KRH93105.1 - 0.019 14.8 4.4 0.38 10.6 1.2 3.5 3 1 1 4 4 4 0 RsgA GTPase MeaB PF03308.16 KRH93105.1 - 0.02 13.9 1.4 0.036 13.0 0.0 2.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KRH93105.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KRH93105.1 - 0.057 13.7 0.1 0.21 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRH93105.1 - 0.065 13.6 0.2 0.24 11.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 KRH93105.1 - 0.078 13.4 4.4 0.13 12.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KRH93105.1 - 0.085 12.9 0.6 0.42 10.7 0.6 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsmJ PF04378.13 KRH93105.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ MMR_HSR1 PF01926.23 KRH93105.1 - 0.11 12.6 3.6 0.21 11.7 0.5 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase TetR_C_8 PF14278.6 KRH93105.1 - 0.12 12.5 5.8 24 5.1 0.1 3.9 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region FliL PF03748.14 KRH93105.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.1 3 1 0 3 3 2 0 Flagellar basal body-associated protein FliL FYRN PF05964.14 KRH93108.1 - 2.6e-11 43.2 0.2 2.6e-11 43.2 0.2 1.7 2 0 0 2 2 2 1 F/Y-rich N-terminus 6PGD PF00393.19 KRH93110.1 - 1.8e-29 103.1 0.9 2.3e-29 102.7 0.9 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KRH93110.1 - 2.4e-28 99.3 0.0 5.7e-19 68.8 0.0 2.3 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KRH93110.1 - 0.00054 20.0 0.0 0.0016 18.5 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KRH93110.1 - 0.002 17.8 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KRH93110.1 - 0.0038 17.8 0.0 0.0087 16.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 KRH93110.1 - 0.024 14.6 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KRH93110.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KRH93110.1 - 0.09 12.1 0.0 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-RVT PF13966.6 KRH93111.1 - 0.0062 17.2 0.4 0.013 16.2 0.0 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HSP90 PF00183.18 KRH93113.1 - 3e-104 349.8 16.9 3.5e-104 349.6 16.9 1.0 1 0 0 1 1 1 1 Hsp90 protein Sec62 PF03839.16 KRH93114.1 - 9 5.7 9.2 1.7 8.1 5.1 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 DUF4451 PF14616.6 KRH93116.1 - 1.4e-17 64.0 10.0 1.4e-17 64.0 10.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) zf-C2H2_jaz PF12171.8 KRH93116.1 - 0.015 15.6 6.4 1.1 9.6 0.9 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1128 PF06569.11 KRH93117.1 - 0.0047 16.9 0.1 0.0047 16.9 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1128) MbeD_MobD PF04899.12 KRH93117.1 - 0.0058 16.7 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 MbeD/MobD like DUF948 PF06103.11 KRH93117.1 - 0.0062 16.8 2.4 0.016 15.4 2.4 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) LPP PF04728.13 KRH93117.1 - 0.0095 16.3 1.9 0.028 14.8 1.9 1.8 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF148 PF02520.17 KRH93117.1 - 0.023 14.8 3.2 0.023 14.8 3.2 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 DNA_repr_REX1B PF14966.6 KRH93117.1 - 0.042 14.5 0.6 0.14 12.9 0.6 1.8 1 0 0 1 1 1 0 DNA repair REX1-B NPV_P10 PF05531.12 KRH93117.1 - 0.06 13.8 3.7 0.18 12.3 0.8 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KRH93117.1 - 0.095 12.7 5.7 0.32 11.0 2.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 KRH93117.1 - 0.16 12.0 2.0 0.22 11.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KRH93117.1 - 1.2 9.6 11.3 1.5 9.3 5.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Nucleoporin_FG2 PF15967.5 KRH93119.1 - 0.099 11.2 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Ribosomal_L6e PF01159.19 KRH93120.1 - 0.061 13.9 2.4 0.062 13.8 0.9 1.7 1 1 1 2 2 2 0 Ribosomal protein L6e Kinesin PF00225.23 KRH93121.1 - 2.4e-66 223.9 17.0 2.8e-41 141.5 10.4 2.4 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KRH93121.1 - 6.3e-18 65.1 0.2 2.6e-17 63.1 0.2 2.1 1 0 0 1 1 1 1 Microtubule binding DUF5394 PF17372.2 KRH93122.1 - 0.13 11.8 1.8 0.17 11.4 1.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5394) RNA_pol_Rpb2_3 PF04565.16 KRH93124.1 - 4.9e-21 74.7 0.0 1.1e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KRH93124.1 - 6.7e-07 29.0 0.0 0.003 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 KRH93124.1 - 4.1e-05 23.8 0.0 0.00021 21.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 Presenilin PF01080.17 KRH93124.1 - 0.53 9.0 35.8 0.52 9.0 17.1 2.5 2 0 0 2 2 2 0 Presenilin ASC PF00858.24 KRH93124.1 - 1.1 8.1 24.6 0.52 9.2 6.4 2.7 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel LAP1C PF05609.12 KRH93124.1 - 3 6.8 33.3 1.6 7.7 10.8 2.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Caldesmon PF02029.15 KRH93124.1 - 3.9 6.1 43.7 0.89 8.2 10.1 2.4 2 1 0 2 2 2 0 Caldesmon Otopetrin PF03189.13 KRH93124.1 - 5.4 5.7 13.7 2.1 7.1 5.4 2.7 2 0 0 2 2 2 0 Otopetrin CDC45 PF02724.14 KRH93124.1 - 6.5 4.9 44.9 0.41 8.9 19.5 2.3 2 0 0 2 2 2 0 CDC45-like protein Dapper PF15268.6 KRH93124.1 - 8.1 5.2 30.3 0.81 8.5 11.8 2.2 2 0 0 2 2 2 0 Dapper TT_ORF1 PF02956.14 KRH93124.1 - 8.5 4.9 25.2 2.6 6.6 14.9 2.5 2 0 0 2 2 2 0 TT viral orf 1 DEAD_2 PF06733.15 KRH93125.1 - 3.4e-36 124.5 14.2 9.3e-23 80.7 4.1 2.8 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.15 KRH93125.1 - 4.5e-07 30.0 13.0 0.00017 21.7 0.0 3.7 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KRH93125.1 - 0.0012 18.7 2.2 0.092 12.5 0.1 3.2 2 2 1 3 3 3 1 DEAD/DEAH box helicase Zot PF05707.12 KRH93125.1 - 0.0029 17.3 0.2 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) PhoH PF02562.16 KRH93125.1 - 0.029 13.8 1.3 2.4 7.5 0.3 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 KRH93125.1 - 0.067 13.5 0.6 9.1 6.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF4678 PF15727.5 KRH93125.1 - 0.17 11.2 5.1 3 7.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) Adaptin_N PF01602.20 KRH93126.1 - 0.0087 14.7 1.5 0.014 14.0 1.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region DUF496 PF04363.12 KRH93126.1 - 0.082 12.9 5.2 2.7 8.1 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF496) RVT_1 PF00078.27 KRH93127.1 - 5.3e-11 42.5 0.5 1.6e-10 40.9 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH93127.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain OS-D PF03392.13 KRH93128.1 - 0.038 14.1 6.0 0.043 13.9 6.0 1.1 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF1027 PF06265.11 KRH93129.1 - 0.0074 16.3 0.1 0.0089 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1027) ARL2_Bind_BART PF11527.8 KRH93129.1 - 0.048 13.8 0.4 0.052 13.7 0.4 1.0 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Arf PF00025.21 KRH93131.1 - 7e-22 77.7 0.0 7.9e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KRH93131.1 - 2.3e-08 33.8 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KRH93131.1 - 2.9e-08 33.4 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KRH93131.1 - 4.5e-08 32.7 0.0 6.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KRH93131.1 - 1.1e-07 32.0 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KRH93131.1 - 5.4e-06 26.5 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KRH93131.1 - 6e-06 25.6 0.2 0.00036 19.8 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit IIGP PF05049.13 KRH93131.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KRH93131.1 - 0.014 15.3 0.5 0.23 11.4 0.0 2.3 1 1 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KRH93131.1 - 0.031 14.8 0.0 0.05 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KRH93131.1 - 0.067 13.0 0.3 0.28 10.9 0.1 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KRH93131.1 - 0.067 13.3 0.3 2.6 8.1 0.2 2.2 1 1 1 2 2 2 0 Dynamin family NACHT PF05729.12 KRH93131.1 - 0.07 13.0 0.0 0.75 9.7 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KRH93131.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KRH93131.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KRH93131.1 - 0.11 11.7 0.0 0.39 10.0 0.0 1.8 1 1 0 1 1 1 0 Septin GTP_EFTU PF00009.27 KRH93131.1 - 0.15 11.6 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 KRH93131.1 - 0.17 12.3 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DDE_3 PF13358.6 KRH93132.1 - 1.2e-06 28.4 0.3 2.1e-06 27.6 0.3 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease NPL4 PF05021.15 KRH93135.1 - 3.4e-08 33.2 1.8 4.8e-08 32.7 1.8 1.1 1 0 0 1 1 1 1 NPL4 family zf-RanBP PF00641.18 KRH93135.1 - 4.1e-05 22.8 3.2 7.9e-05 21.9 3.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DDE_3 PF13358.6 KRH93137.1 - 3.6e-17 62.5 0.4 4.8e-17 62.1 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Coat_F PF07875.12 KRH93137.1 - 0.086 13.1 0.5 0.13 12.5 0.5 1.4 1 0 0 1 1 1 0 Coat F domain DEC-1_N PF04625.13 KRH93141.1 - 0.00042 19.5 4.0 0.00063 18.9 4.0 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region UCR_TM PF02921.14 KRH93141.1 - 0.04 14.4 0.4 0.097 13.2 0.4 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region WD40 PF00400.32 KRH93142.1 - 3.5e-14 52.9 7.9 8.7e-05 23.2 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH93142.1 - 8e-11 42.1 6.3 0.00092 19.5 0.4 4.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KRH93142.1 - 0.019 14.0 1.3 0.18 10.8 0.3 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 KRH93142.1 - 0.086 12.7 0.1 2.3 8.1 0.0 2.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Kelch_6 PF13964.6 KRH93142.1 - 0.26 11.6 2.5 32 5.0 0.1 4.1 5 0 0 5 5 5 0 Kelch motif CAF1A PF12253.8 KRH93143.1 - 6.1e-06 26.3 4.5 1.6e-05 25.0 4.5 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A PA28_alpha PF02251.18 KRH93146.1 - 0.022 14.8 0.0 0.067 13.2 0.0 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit RVT_1 PF00078.27 KRH93147.1 - 2.4e-20 73.0 0.2 3e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tfb5 PF06331.12 KRH93147.1 - 0.03 14.3 0.2 0.067 13.2 0.2 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Coatomer_b_Cpla PF14806.6 KRH93148.1 - 1.2e-19 70.6 2.4 4.5e-19 68.7 2.4 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KRH93148.1 - 9.8e-13 48.2 1.1 2.3e-12 47.0 1.1 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region CSN4_RPN5_eIF3a PF18420.1 KRH93148.1 - 1.8 8.8 3.9 41 4.4 0.1 3.1 3 0 0 3 3 3 0 CSN4/RPN5/eIF3a helix turn helix domain RT_RNaseH PF17917.1 KRH93149.1 - 8.7e-28 96.7 0.0 2.5e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93149.1 - 1.4e-26 93.4 0.5 3.1e-26 92.3 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93149.1 - 2.1e-26 91.9 0.0 7e-26 90.2 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93149.1 - 1.8e-17 63.6 0.0 4.8e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KRH93149.1 - 2.1e-08 34.6 0.0 6.8e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 KRH93149.1 - 1.1e-07 31.8 0.3 3.4e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 KRH93149.1 - 2e-06 27.5 0.0 7.1e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVP PF00077.20 KRH93149.1 - 0.00016 22.0 0.0 0.00058 20.1 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93149.1 - 0.00023 21.7 0.0 0.0007 20.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH93149.1 - 0.0047 16.7 0.3 0.03 14.1 0.1 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH93149.1 - 0.0059 16.4 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 KRH93149.1 - 0.041 13.6 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Rio2_N PF09202.11 KRH93149.1 - 0.077 13.2 1.2 4.4 7.6 0.1 3.4 3 0 0 3 3 3 0 Rio2, N-terminal DUF1758 PF05585.12 KRH93149.1 - 0.083 12.7 2.7 0.24 11.2 0.2 2.7 3 0 0 3 3 3 0 Putative peptidase (DUF1758) RVT_1 PF00078.27 KRH93152.1 - 3e-09 36.7 0.1 5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chordopox_E11 PF06138.12 KRH93152.1 - 0.013 15.8 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus E11 protein EC042_2821 PF18740.1 KRH93152.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase RT_RNaseH PF17917.1 KRH93153.1 - 5.5e-38 129.5 0.3 1.4e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93153.1 - 1.1e-32 112.0 0.3 4.5e-32 110.1 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93153.1 - 3.9e-24 85.4 1.2 9.4e-24 84.1 0.4 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93153.1 - 2.5e-18 66.4 0.0 1.1e-17 64.3 0.0 2.2 3 0 0 3 3 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93153.1 - 5.2e-15 55.3 1.0 1.6e-14 53.7 1.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_IS240 PF13610.6 KRH93153.1 - 0.0008 19.6 0.3 0.0028 17.9 0.3 1.9 1 0 0 1 1 1 1 DDE domain RVP PF00077.20 KRH93153.1 - 0.0016 18.7 0.0 0.0046 17.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH93153.1 - 0.0044 17.5 0.0 0.017 15.7 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_thumb PF06817.14 KRH93153.1 - 0.0095 15.8 0.0 0.032 14.1 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase thumb domain OKR_DC_1 PF01276.20 KRH93153.1 - 0.043 12.6 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DDE_Tnp_IS1595 PF12762.7 KRH93153.1 - 0.049 13.6 0.7 0.18 11.8 0.2 2.2 2 0 0 2 2 2 0 ISXO2-like transposase domain rve_3 PF13683.6 KRH93153.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HGTP_anticodon PF03129.20 KRH93154.1 - 4e-16 58.9 1.0 1.2e-15 57.4 1.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KRH93154.1 - 5.7e-11 42.7 0.8 2e-10 40.9 0.8 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Jiv90 PF14901.6 KRH93155.1 - 0.058 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone CamS PF07537.11 KRH93155.1 - 0.082 12.1 0.4 0.089 11.9 0.4 1.1 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Peptidase_M16 PF00675.20 KRH93159.1 - 3.4e-23 82.3 0.0 6.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KRH93159.1 - 0.031 14.3 0.4 0.19 11.7 0.4 2.2 1 1 0 1 1 1 0 Peptidase M16 inactive domain RT_RNaseH_2 PF17919.1 KRH93160.1 - 3.7e-09 36.5 0.0 4.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93160.1 - 0.022 15.0 0.0 0.055 13.8 0.0 1.6 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF3213 PF11491.8 KRH93160.1 - 0.05 13.8 0.2 0.058 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) POC1 PF10450.9 KRH93162.1 - 0.0022 17.0 0.3 0.0024 16.9 0.3 1.0 1 0 0 1 1 1 1 POC1 chaperone Peptidase_M22 PF00814.25 KRH93163.1 - 2.4e-77 260.3 0.1 2.8e-77 260.0 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Svf1_C PF17187.4 KRH93163.1 - 0.014 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain DUF1640 PF07798.11 KRH93164.1 - 0.055 13.5 6.1 0.12 12.4 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) SNARE PF05739.19 KRH93166.1 - 1.5 8.9 10.4 11 6.1 10.4 2.4 1 1 0 1 1 1 0 SNARE domain DUF3800 PF12686.7 KRH93166.1 - 3.9 8.1 4.9 18 5.9 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) CTP_transf_1 PF01148.20 KRH93167.1 - 3.3e-56 191.0 23.2 6.4e-56 190.0 23.2 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family PSS PF03034.15 KRH93168.1 - 2.6e-62 211.1 40.3 6.4e-55 186.8 17.6 4.1 3 2 1 4 4 4 2 Phosphatidyl serine synthase H_PPase PF03030.16 KRH93168.1 - 0.24 10.0 0.3 0.62 8.6 0.1 1.6 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase HMG_box PF00505.19 KRH93169.1 - 3.2e-18 65.9 23.5 3e-09 37.2 7.2 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KRH93169.1 - 6.2e-16 58.8 20.8 1.7e-08 34.9 7.1 2.6 2 0 0 2 2 2 2 HMG-box domain DUF685 PF05085.12 KRH93169.1 - 0.018 14.4 0.3 0.029 13.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF685) DUF3106 PF11304.8 KRH93169.1 - 0.041 14.3 6.7 0.59 10.6 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) COX4 PF02936.14 KRH93169.1 - 0.047 13.7 1.3 0.047 13.7 1.3 3.2 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV LcrV PF04792.12 KRH93169.1 - 0.077 12.3 4.3 0.15 11.3 4.3 1.4 1 1 0 1 1 1 0 V antigen (LcrV) protein DUF1289 PF06945.13 KRH93169.1 - 0.52 10.2 2.9 3.4 7.6 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1289) HDV_ag PF01517.18 KRH93169.1 - 2.5 7.9 7.5 1.8 8.3 5.2 1.8 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen DUF3591 PF12157.8 KRH93170.1 - 2.8e-44 151.5 4.8 2.2e-40 138.7 4.8 3.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KRH93170.1 - 1.4e-16 60.3 0.3 1.8e-15 56.8 0.1 2.8 2 0 0 2 2 2 1 Bromodomain zf-CCHC_6 PF15288.6 KRH93170.1 - 2.9e-05 23.8 1.9 6.6e-05 22.7 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle PTH2 PF01981.16 KRH93170.1 - 0.096 13.0 0.3 0.25 11.6 0.3 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 TLC PF03219.14 KRH93171.1 - 3.3e-49 168.0 36.4 5.5e-49 167.2 36.4 1.3 1 1 0 1 1 1 1 TLC ATP/ADP transporter OAD_gamma PF04277.13 KRH93171.1 - 0.0046 17.5 1.4 0.57 10.8 0.4 3.1 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain Adeno_E3_14_5 PF04834.12 KRH93171.1 - 0.29 11.7 3.7 0.65 10.6 0.2 2.8 2 0 0 2 2 2 0 Early E3 14.5 kDa protein T3SSipB PF16535.5 KRH93173.1 - 0.085 13.3 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF5434 PF17502.2 KRH93173.1 - 0.52 10.3 4.8 1.1 9.2 4.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5434) WD40 PF00400.32 KRH93174.1 - 9.7e-18 64.2 6.2 0.00052 20.8 0.1 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 KRH93174.1 - 0.0034 17.3 1.5 0.74 9.7 0.1 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Parvo_NS1 PF01057.17 KRH93174.1 - 0.028 13.5 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PQQ_2 PF13360.6 KRH93174.1 - 0.13 11.9 0.0 0.3 10.6 0.0 1.8 1 1 1 2 2 2 0 PQQ-like domain Bromodomain PF00439.25 KRH93175.1 - 4.9e-35 119.4 5.9 5.2e-18 64.9 0.5 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KRH93175.1 - 8.3e-10 38.7 3.9 8.3e-10 38.7 3.9 2.1 2 1 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation AsnA PF03590.15 KRH93176.1 - 1.2e-33 116.8 3.5 1.6e-23 83.6 0.3 2.1 2 0 0 2 2 2 2 Aspartate-ammonia ligase Proteasome PF00227.26 KRH93179.1 - 1.2e-29 103.2 0.0 1.3e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.26 KRH93180.1 - 7.4e-29 100.6 0.1 1e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Uds1 PF15456.6 KRH93180.1 - 0.075 13.2 0.2 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 Up-regulated During Septation gag-asp_proteas PF13975.6 KRH93182.1 - 2.2e-05 24.9 0.1 0.00016 22.2 0.0 2.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH93182.1 - 0.00042 20.9 0.0 0.0021 18.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 KRH93182.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative peptidase (DUF1758) RVP PF00077.20 KRH93182.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease RAMPs PF03787.15 KRH93182.1 - 1.3 9.1 8.5 1.6 8.7 7.8 1.5 1 1 0 1 1 1 0 RAMP superfamily Ank_5 PF13857.6 KRH93183.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KRH93183.1 - 0.03 14.9 0.1 0.17 12.5 0.0 2.1 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) UNC-93 PF05978.16 KRH93183.1 - 0.053 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF4834 PF16118.5 KRH93184.1 - 2.7 9.0 0.0 2.7 9.0 0.0 5.4 3 3 0 3 3 3 0 Domain of unknown function (DUF4834) DUF948 PF06103.11 KRH93184.1 - 7.4 6.9 6.9 8.5 6.7 0.8 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec20 PF03908.13 KRH93185.1 - 5.1e-08 32.7 4.3 7.2e-08 32.2 3.5 1.6 1 1 1 2 2 2 1 Sec20 B-block_TFIIIC PF04182.12 KRH93185.1 - 0.013 15.7 0.2 0.034 14.3 0.2 1.8 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC MAP PF03642.13 KRH93185.1 - 0.04 14.2 3.0 0.074 13.4 1.0 2.0 1 1 1 2 2 2 0 MAP domain MCU PF04678.13 KRH93185.1 - 0.051 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Pkinase PF00069.25 KRH93186.1 - 4e-20 72.3 0.0 4.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93186.1 - 4.3e-07 29.5 0.0 5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRH93186.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TPR_1 PF00515.28 KRH93187.1 - 3.4e-15 55.1 5.1 0.00011 21.8 0.3 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KRH93187.1 - 6.6e-13 47.7 3.1 0.00033 20.6 0.1 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KRH93187.1 - 4.2e-12 45.6 1.9 2.1e-06 27.3 0.2 3.4 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KRH93187.1 - 1.7e-11 43.6 1.1 0.00026 21.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KRH93187.1 - 1.7e-08 34.0 5.1 0.076 13.3 0.0 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KRH93187.1 - 9.2e-08 31.6 0.1 0.04 13.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KRH93187.1 - 2.6e-06 27.9 0.1 0.0086 16.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KRH93187.1 - 9.5e-06 25.9 0.4 0.79 10.5 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KRH93187.1 - 9.5e-05 22.6 0.0 2.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KRH93187.1 - 0.0011 19.5 0.0 0.093 13.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 KRH93187.1 - 0.0015 18.5 0.1 0.044 13.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 KRH93187.1 - 0.0061 16.3 0.4 0.12 12.2 0.2 2.3 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_14 PF13428.6 KRH93187.1 - 0.007 17.1 0.0 2.7 9.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2225 PF09986.9 KRH93187.1 - 0.021 14.6 3.7 0.078 12.7 2.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 KRH93187.1 - 0.025 14.8 1.8 0.15 12.3 0.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 KRH93187.1 - 0.029 15.0 0.1 0.091 13.5 0.1 1.9 1 0 0 1 1 1 0 Sel1 repeat MIT PF04212.18 KRH93187.1 - 0.041 14.0 6.1 1.8 8.7 1.4 3.9 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KRH93187.1 - 0.042 14.3 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KRH93187.1 - 0.063 13.4 6.5 0.16 12.0 0.4 3.2 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 KRH93187.1 - 0.073 12.3 0.0 0.25 10.5 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 KRH93188.1 - 1.6e-29 103.3 0.0 1.9e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase NB-LRR PF12061.8 KRH93188.1 - 0.0087 15.4 0.4 0.012 14.9 0.4 1.3 1 0 0 1 1 1 1 Late blight resistance protein R1 Actin_micro PF17003.5 KRH93190.1 - 1.3e-42 146.4 24.1 5.2e-40 137.8 24.1 2.8 1 1 0 1 1 1 1 Putative actin-like family Gp-FAR-1 PF05823.12 KRH93191.1 - 0.0034 17.7 0.2 0.0042 17.4 0.2 1.1 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) BET PF17035.5 KRH93191.1 - 0.0066 16.6 0.2 0.01 16.0 0.1 1.5 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation rve PF00665.26 KRH93192.1 - 6.7e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 KRH93192.1 - 0.012 15.6 0.0 0.046 13.8 0.0 1.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVT_thumb PF06817.14 KRH93193.1 - 3.1e-06 26.9 1.6 4.2e-06 26.5 0.3 2.0 2 1 0 2 2 2 1 Reverse transcriptase thumb domain RVT_1 PF00078.27 KRH93193.1 - 4.4e-05 23.1 0.2 9.2e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) G_glu_transpept PF01019.21 KRH93193.1 - 0.032 13.0 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase HxlR PF01638.17 KRH93193.1 - 0.054 13.3 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix zf-C2H2 PF00096.26 KRH93194.1 - 1.2e-07 31.8 10.4 0.00038 20.8 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KRH93194.1 - 2.3e-05 24.6 4.3 2.3e-05 24.6 4.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KRH93194.1 - 0.0067 17.2 8.4 0.052 14.4 0.6 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KRH93194.1 - 0.013 15.2 2.6 0.019 14.6 0.4 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 KRH93194.1 - 0.033 14.5 3.5 0.2 12.0 3.1 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KRH93194.1 - 0.058 14.0 1.7 1.5 9.5 0.1 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KRH93194.1 - 0.059 14.1 1.2 0.12 13.1 1.2 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger DUF1655 PF07868.11 KRH93194.1 - 0.086 12.9 2.0 0.76 9.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1655) ORC6 PF05460.13 KRH93195.1 - 0.0044 16.3 10.1 0.0071 15.7 10.1 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DDHD PF02862.17 KRH93195.1 - 0.0084 16.3 5.8 0.013 15.6 5.8 1.4 1 0 0 1 1 1 1 DDHD domain Zip PF02535.22 KRH93195.1 - 0.025 13.8 1.9 0.036 13.3 1.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Arc_PepC_II PF06847.11 KRH93195.1 - 0.045 14.3 0.0 0.045 14.3 0.0 3.4 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II Ndc1_Nup PF09531.10 KRH93195.1 - 0.052 12.2 1.2 0.06 12.0 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 KRH93195.1 - 0.25 11.2 18.5 0.5 10.2 18.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KRH93195.1 - 0.25 9.6 15.4 0.38 9.0 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 KRH93195.1 - 0.58 10.2 11.2 0.98 9.5 11.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region CLN3 PF02487.17 KRH93195.1 - 0.68 8.9 3.5 1.1 8.3 2.5 1.8 2 0 0 2 2 2 0 CLN3 protein Neur_chan_memb PF02932.16 KRH93195.1 - 1.2 9.2 5.8 1.7 8.6 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpc4 PF05132.14 KRH93195.1 - 2.9 8.3 9.7 5.4 7.4 9.7 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KRH93195.1 - 3.3 6.4 14.9 5.2 5.7 14.9 1.3 1 0 0 1 1 1 0 Presenilin Thioredoxin PF00085.20 KRH93196.1 - 1.2e-11 44.5 0.0 1.4e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 KRH93196.1 - 0.00015 21.8 0.6 0.00015 21.8 0.6 3.7 2 2 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KRH93196.1 - 0.0003 21.1 0.0 0.0015 18.8 0.0 2.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.6 KRH93196.1 - 0.0021 18.2 2.4 0.003 17.7 0.0 2.4 3 1 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 KRH93196.1 - 0.0075 16.7 0.9 0.09 13.2 0.1 3.0 3 1 0 3 3 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 KRH93196.1 - 0.0077 16.4 0.3 0.068 13.4 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin Redoxin PF08534.10 KRH93196.1 - 0.0079 15.9 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 KRH93196.1 - 0.0097 15.7 0.3 0.43 10.4 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin AhpC-TSA PF00578.21 KRH93196.1 - 0.015 15.2 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family Cation_ATPase PF13246.6 KRH93196.1 - 0.064 13.3 0.5 0.32 11.1 0.1 2.5 2 0 0 2 2 2 0 Cation transport ATPase (P-type) DUF836 PF05768.14 KRH93196.1 - 0.11 12.9 0.4 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) gag-asp_proteas PF13975.6 KRH93199.1 - 8e-09 36.0 0.0 2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH93199.1 - 1.6e-07 31.9 0.0 3.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH93199.1 - 4.4e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 KRH93199.1 - 0.01 15.7 0.0 0.034 13.9 0.0 2.0 1 1 0 1 1 1 1 Putative peptidase (DUF1758) RVP PF00077.20 KRH93199.1 - 0.03 14.6 0.1 0.24 11.7 0.0 2.4 2 1 0 2 2 2 0 Retroviral aspartyl protease DNA_pol3_theta PF06440.11 KRH93199.1 - 0.039 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase III, theta subunit RAMPs PF03787.15 KRH93199.1 - 0.075 13.1 4.3 0.4 10.7 4.3 2.0 1 1 0 1 1 1 0 RAMP superfamily AMP-binding PF00501.28 KRH93200.1 - 3.5e-75 253.2 0.0 7.6e-57 192.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme zf-rbx1 PF12678.7 KRH93201.1 - 7.2e-23 80.6 15.1 9.2e-23 80.3 15.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KRH93201.1 - 6.1e-17 61.5 9.3 7.2e-17 61.2 9.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KRH93201.1 - 1.2e-06 28.8 16.5 5.6e-05 23.4 16.4 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KRH93201.1 - 3.1e-05 23.7 15.7 0.0056 16.5 15.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH93201.1 - 0.0001 22.1 14.1 0.0034 17.2 14.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KRH93201.1 - 0.00062 19.3 9.8 0.00062 19.3 9.8 2.0 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type TBCC PF07986.12 KRH93201.1 - 0.01 15.5 3.1 0.013 15.2 3.1 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor C zf-RING_11 PF17123.5 KRH93201.1 - 0.014 15.1 13.9 1.7 8.5 13.9 2.6 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KRH93201.1 - 0.016 15.3 12.4 0.034 14.3 12.4 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 KRH93201.1 - 0.037 13.9 12.4 0.18 11.7 5.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRH93201.1 - 0.049 13.7 7.4 0.14 12.2 7.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger HTH_Tnp_Tc3_1 PF11427.8 KRH93201.1 - 0.07 13.0 0.2 0.42 10.5 0.1 2.1 1 1 1 2 2 2 0 Tc3 transposase zinc_ribbon_16 PF17034.5 KRH93201.1 - 0.11 12.7 9.5 0.49 10.6 9.5 1.9 1 1 0 1 1 1 0 Zinc-ribbon like family zf-HC5HC2H_2 PF13832.6 KRH93201.1 - 0.21 11.8 12.3 0.37 11.0 12.3 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KRH93201.1 - 0.28 11.4 13.2 2.6 8.4 13.2 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 KRH93201.1 - 0.98 9.4 13.8 21 5.2 13.8 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KRH93201.1 - 1.9 8.7 8.8 1.5 9.0 0.8 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING C1_2 PF03107.16 KRH93201.1 - 2.4 8.5 10.7 0.32 11.4 2.6 2.5 3 0 0 3 3 3 0 C1 domain WD40 PF00400.32 KRH93202.1 - 1.5e-12 47.8 1.8 0.56 11.2 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat PIN_8 PF18476.1 KRH93204.1 - 0.033 14.0 8.2 0.27 11.1 1.2 2.3 2 0 0 2 2 2 0 PIN like domain DNA_pol_A_exo1 PF01612.20 KRH93204.1 - 0.037 13.7 1.8 0.078 12.7 0.9 1.9 1 1 1 2 2 2 0 3'-5' exonuclease Sugar_tr PF00083.24 KRH93205.1 - 1e-18 67.5 11.0 1.3e-18 67.2 11.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2749 PF10907.8 KRH93205.1 - 0.12 12.5 1.2 0.5 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) AAA PF00004.29 KRH93208.1 - 1e-47 161.9 0.9 3e-40 137.7 0.1 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KRH93208.1 - 1.4e-10 41.9 0.0 0.0006 20.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 KRH93208.1 - 8.1e-09 35.1 0.4 2.2e-08 33.8 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 KRH93208.1 - 4.7e-08 33.4 0.5 0.0013 19.1 0.3 3.4 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KRH93208.1 - 4.1e-07 29.9 0.0 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 KRH93208.1 - 4.8e-07 29.9 0.1 0.0004 20.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 KRH93208.1 - 8.5e-07 28.9 0.1 0.025 14.3 0.3 3.3 2 2 1 3 3 3 2 DEAD/DEAH box helicase AAA_7 PF12775.7 KRH93208.1 - 1.3e-06 28.1 0.1 0.021 14.3 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 KRH93208.1 - 1.7e-06 28.6 0.2 0.0022 18.5 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.14 KRH93208.1 - 2.5e-06 27.7 0.4 3.4e-05 24.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KRH93208.1 - 1.2e-05 24.7 0.0 0.028 13.6 0.0 2.5 3 0 0 3 3 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KRH93208.1 - 3.8e-05 24.0 0.4 0.054 13.9 0.0 4.0 4 1 0 4 4 3 1 RNA helicase Sigma54_activat PF00158.26 KRH93208.1 - 4.6e-05 23.2 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KRH93208.1 - 5.2e-05 23.1 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KRH93208.1 - 7e-05 22.9 5.1 0.029 14.4 0.1 4.0 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 KRH93208.1 - 7.4e-05 22.2 0.0 0.005 16.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KRH93208.1 - 8.3e-05 22.0 1.7 0.078 12.3 0.0 3.2 3 1 1 4 4 3 2 KaiC DUF2075 PF09848.9 KRH93208.1 - 9.2e-05 21.8 0.6 0.29 10.3 0.2 3.2 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KRH93208.1 - 0.00014 22.0 4.0 0.25 11.3 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit PhoH PF02562.16 KRH93208.1 - 0.00018 21.0 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_18 PF13238.6 KRH93208.1 - 0.00029 21.4 1.3 0.0034 17.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain DNA_pol3_delta2 PF13177.6 KRH93208.1 - 0.00047 20.0 0.2 0.19 11.5 0.1 3.7 2 2 0 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KRH93208.1 - 0.00062 20.1 0.0 0.35 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KRH93208.1 - 0.0019 18.2 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KRH93208.1 - 0.0019 17.9 0.1 0.025 14.3 0.1 2.6 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KRH93208.1 - 0.0026 17.7 0.4 1.9 8.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain DUF815 PF05673.13 KRH93208.1 - 0.0029 16.8 0.1 0.033 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 KRH93208.1 - 0.0031 17.1 0.1 2.2 7.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KRH93208.1 - 0.0038 17.4 0.0 0.066 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KRH93208.1 - 0.005 16.6 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KRH93208.1 - 0.0052 16.7 2.7 0.038 13.8 0.2 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_3 PF07726.11 KRH93208.1 - 0.0068 16.3 0.1 0.029 14.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KRH93208.1 - 0.0069 15.6 0.0 0.84 8.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 KRH93208.1 - 0.0076 15.7 0.7 3.8 6.9 0.0 3.3 2 1 0 3 3 3 1 Bacterial TniB protein Roc PF08477.13 KRH93208.1 - 0.01 16.1 0.1 0.71 10.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KRH93208.1 - 0.02 14.8 9.3 0.32 10.9 0.4 3.8 3 2 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KRH93208.1 - 0.057 13.7 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KRH93208.1 - 0.064 13.0 5.0 2.7 7.7 2.3 2.8 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KRH93208.1 - 0.074 12.8 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KRH93208.1 - 0.11 11.5 0.1 16 4.5 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein zf-C4_Topoisom PF01396.19 KRH93210.1 - 0.0021 17.8 0.2 0.0034 17.1 0.2 1.3 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger T4_baseplate PF12322.8 KRH93210.1 - 0.0025 17.3 0.0 0.0026 17.3 0.0 1.0 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-ACC PF17848.1 KRH93210.1 - 0.0036 17.4 0.2 0.0053 16.8 0.2 1.2 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KRH93210.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KRH93210.1 - 0.037 14.0 0.1 0.05 13.6 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ISL3 PF14690.6 KRH93210.1 - 0.085 13.5 0.2 9 7.0 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 KRH93210.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Zinc ribbon domain DDE_Tnp_IS1595 PF12762.7 KRH93211.1 - 1.4e-07 31.6 0.0 1.7e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DZR PF12773.7 KRH93213.1 - 0.052 13.6 5.8 0.67 10.0 3.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.19 KRH93213.1 - 0.53 10.7 0.2 0.53 10.7 0.2 2.6 1 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein HypA PF01155.19 KRH93213.1 - 4.2 7.4 6.1 11 6.1 6.1 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KRH93213.1 - 5.7 6.6 8.9 0.74 9.5 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 KRH93213.1 - 6.7 6.8 9.7 0.094 12.8 1.9 2.0 2 1 0 2 2 2 0 BED zinc finger zf-ANAPC11 PF12861.7 KRH93214.1 - 5.6e-19 68.0 14.6 6.7e-19 67.7 14.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KRH93214.1 - 1.6e-18 66.7 17.1 1.6e-18 66.7 17.1 1.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KRH93214.1 - 7.7e-08 32.5 21.6 6.7e-07 29.5 18.1 2.4 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KRH93214.1 - 8.7e-05 22.3 19.2 0.00021 21.1 16.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRH93214.1 - 0.00013 21.7 16.4 0.00013 21.7 16.4 2.4 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRH93214.1 - 0.0002 21.2 19.3 0.00072 19.4 11.9 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KRH93214.1 - 0.0019 18.2 9.6 0.0019 18.2 9.6 2.4 2 1 0 2 2 2 1 Zinc-finger zf-RING_UBOX PF13445.6 KRH93214.1 - 0.0032 17.4 9.2 0.0043 17.0 8.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KRH93214.1 - 0.013 15.5 18.8 0.1 12.6 17.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KRH93214.1 - 0.025 14.2 18.2 0.96 9.1 18.2 2.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KRH93214.1 - 0.059 13.4 15.4 0.39 10.8 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Disaggr_assoc PF08480.10 KRH93214.1 - 0.06 13.2 0.1 0.76 9.6 0.0 1.9 1 1 1 2 2 2 0 Disaggregatase related zf-Nse PF11789.8 KRH93214.1 - 0.7 9.8 9.1 1 9.2 9.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 KRH93214.1 - 2 8.6 15.9 0.92 9.7 10.5 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 KRH93214.1 - 2.9 7.6 15.8 9.4 6.0 10.6 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 KRH93214.1 - 5.9 6.7 14.5 83 3.1 14.5 2.6 1 1 0 1 1 1 0 RING-like zinc finger Ferritin PF00210.24 KRH93215.1 - 3.8e-25 88.5 2.9 4.6e-25 88.2 2.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain GABP-alpha PF11620.8 KRH93215.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 GA-binding protein alpha chain TB2_DP1_HVA22 PF03134.19 KRH93216.1 - 1.3e-10 41.0 6.2 2.2e-10 40.3 6.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Rsa3 PF14615.6 KRH93216.1 - 0.016 14.8 0.2 0.035 13.7 0.2 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DUF3952 PF13130.6 KRH93217.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) CRAL_TRIO_2 PF13716.6 KRH93217.1 - 0.13 12.4 1.9 0.19 11.9 1.9 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain WD40 PF00400.32 KRH93218.1 - 0.15 12.9 6.0 0.18 12.8 0.4 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF1283 PF06932.11 KRH93219.1 - 0.0052 17.0 0.1 0.0062 16.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) SNF2_N PF00176.23 KRH93220.1 - 3.5e-42 144.4 0.1 6.5e-42 143.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KRH93220.1 - 7e-08 32.7 3.1 1e-07 32.1 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KRH93220.1 - 0.0056 16.5 0.0 0.036 13.8 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KRH93220.1 - 0.011 14.7 0.0 0.89 8.4 0.0 2.4 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 DUF1878 PF08963.10 KRH93220.1 - 0.02 15.4 0.6 0.11 13.0 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1878) DUF1043 PF06295.12 KRH93220.1 - 0.033 14.2 0.8 0.033 14.2 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DASH_Dad1 PF08649.10 KRH93220.1 - 1.9 8.7 8.4 6.1 7.1 0.0 4.4 5 0 0 5 5 5 0 DASH complex subunit Dad1 DEAD PF00270.29 KRH93221.1 - 5.6e-18 65.3 1.8 1.2e-16 61.0 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH93221.1 - 7e-15 55.3 6.5 2e-14 53.8 0.9 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 KRH93221.1 - 1.3e-05 25.2 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 KRH93221.1 - 2.5e-05 24.3 2.3 7.4e-05 22.8 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KRH93221.1 - 0.00026 20.3 0.9 0.00039 19.8 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KRH93221.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Helicase SecA_DEAD PF07517.14 KRH93221.1 - 0.066 12.5 2.3 4.5 6.5 0.0 2.5 1 1 0 2 2 2 0 SecA DEAD-like domain GerE PF00196.19 KRH93221.1 - 0.54 9.8 5.0 14 5.3 0.2 3.6 3 1 0 3 3 3 0 Bacterial regulatory proteins, luxR family CYTL1 PF15153.6 KRH93223.1 - 0.066 13.2 1.4 0.068 13.1 1.4 1.2 1 0 0 1 1 1 0 Cytokine-like protein 1 Apo-CII PF05355.11 KRH93223.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 2 0 0 2 2 2 0 Apolipoprotein C-II DDE_Tnp_IS1595 PF12762.7 KRH93224.1 - 1.7e-21 76.8 0.0 2e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain MciZ PF13072.6 KRH93224.1 - 0.56 10.1 3.0 0.97 9.3 0.8 2.4 2 1 0 2 2 2 0 Mother cell inhibitor of FtsZ Cas_CXXC_CXXC PF09706.10 KRH93226.1 - 0.054 13.7 0.1 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) tRNA_bind PF01588.20 KRH93227.1 - 2.5e-22 78.8 0.0 4.4e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KRH93227.1 - 0.016 15.4 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KRH93227.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Topoisom_I_N PF02919.15 KRH93227.1 - 0.051 13.1 0.3 0.13 11.7 0.3 1.7 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment SpoU_sub_bind PF08032.12 KRH93227.1 - 0.094 13.0 0.0 41 4.5 0.0 3.6 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Slx4 PF09494.10 KRH93228.1 - 0.041 13.8 0.1 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Slx4 endonuclease NifT PF06988.11 KRH93230.1 - 0.057 13.2 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 NifT/FixU protein Lipin_mid PF16876.5 KRH93230.1 - 0.066 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Utp14 PF04615.13 KRH93231.1 - 8.8e-24 84.1 26.4 4.3e-23 81.8 0.7 2.5 1 1 0 2 2 2 2 Utp14 protein DUF1451 PF07295.11 KRH93231.1 - 5.8 6.9 8.8 5.1 7.1 1.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain TFIID_30kDa PF03540.13 KRH93232.1 - 5.8e-17 61.4 0.0 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KRH93232.1 - 0.018 15.0 0.1 4.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Bromodomain associated HeH PF12949.7 KRH93232.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Iron_traffic PF04362.14 KRH93232.1 - 0.051 13.3 0.2 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking TAF PF02969.17 KRH93232.1 - 0.14 12.4 1.2 0.95 9.7 1.3 2.1 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Acyltransferase PF01553.21 KRH93233.1 - 2.6e-13 49.8 0.8 4.6e-13 48.9 0.3 1.7 2 0 0 2 2 2 1 Acyltransferase Wzy_C PF04932.15 KRH93233.1 - 0.07 12.8 1.3 0.14 11.7 1.3 1.5 1 0 0 1 1 1 0 O-Antigen ligase RicinB_lectin_2 PF14200.6 KRH93234.1 - 1.6e-05 25.6 0.1 0.015 16.0 0.0 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KRH93234.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF2418 PF10332.9 KRH93235.1 - 0.58 10.7 4.9 1.6 9.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) E1-E2_ATPase PF00122.20 KRH93238.1 - 1.7e-24 86.3 0.4 5.7e-24 84.6 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KRH93238.1 - 1.6e-21 77.6 0.0 2.4e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRH93238.1 - 9.6e-06 25.6 0.0 3.1e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KRH93238.1 - 0.05 13.3 7.4 1.3 8.7 0.1 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase PTR2 PF00854.21 KRH93239.1 - 2.2e-33 115.7 10.3 4.1e-33 114.8 10.3 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KRH93239.1 - 0.09 11.7 16.4 0.076 11.9 13.9 1.8 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF5345 PF17280.2 KRH93239.1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5345) DUF5056 PF16479.5 KRH93239.1 - 1.2 9.4 6.3 0.81 10.0 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5056) Sec66 PF09802.9 KRH93240.1 - 0.00021 20.9 7.6 0.0011 18.6 7.5 2.0 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 NTPase_I-T PF01931.18 KRH93240.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF3492 PF11997.8 KRH93240.1 - 0.05 13.3 0.8 0.48 10.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) THOC7 PF05615.13 KRH93241.1 - 0.021 15.1 1.4 0.034 14.4 1.4 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 TMF_DNA_bd PF12329.8 KRH93241.1 - 0.023 14.7 4.0 0.023 14.7 4.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 KRH93241.1 - 0.034 14.5 1.9 0.034 14.5 1.9 1.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 KRH93241.1 - 0.29 11.5 6.3 0.36 11.2 6.3 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Osmo_CC PF08946.10 KRH93241.1 - 1.6 9.0 6.2 0.89 9.9 2.5 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Glutaredoxin PF00462.24 KRH93243.1 - 1.7e-06 28.1 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KRH93243.1 - 0.049 14.0 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain KH_1 PF00013.29 KRH93245.1 - 1.3e-05 24.9 0.4 2.1e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KRH93245.1 - 0.032 14.0 0.1 0.055 13.3 0.1 1.3 1 0 0 1 1 1 0 KH domain MFS_1_like PF12832.7 KRH93246.1 - 3.1e-06 26.3 16.7 4.8e-06 25.7 16.7 1.2 1 0 0 1 1 1 1 MFS_1 like family SdpI PF13630.6 KRH93246.1 - 0.17 12.0 0.0 0.17 12.0 0.0 3.7 4 1 0 4 4 4 0 SdpI/YhfL protein family TMEM208_SND2 PF05620.11 KRH93246.1 - 6.1 6.6 7.2 6.4 6.5 0.1 3.2 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 WD40 PF00400.32 KRH93247.1 - 3e-26 91.2 9.6 3.4e-08 34.0 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KRH93247.1 - 7.1e-24 84.6 20.8 7.1e-24 84.6 20.8 1.7 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KRH93247.1 - 0.00049 20.3 0.0 1 9.7 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain COPI_C PF06957.11 KRH93247.1 - 0.0047 15.7 0.1 0.009 14.8 0.1 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus RecR PF02132.15 KRH93247.1 - 0.031 13.9 1.5 0.074 12.6 1.5 1.6 1 0 0 1 1 1 0 RecR protein DDE_3 PF13358.6 KRH93248.1 - 6.3e-06 26.0 0.2 7.6e-06 25.7 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ACI44 PF15270.6 KRH93249.1 - 0.024 14.8 1.6 0.092 13.0 1.6 2.0 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor Peptidase_M1_N PF17900.1 KRH93250.1 - 5.3e-13 49.6 0.0 6.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KRH93251.1 - 1.8e-58 197.7 0.8 1.4e-57 194.8 0.8 2.0 1 1 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KRH93252.1 - 7e-10 38.9 0.1 4.8e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 ERAP1-like C-terminal domain PuR_N PF09182.10 KRH93253.1 - 0.17 11.9 0.6 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal MgtE PF01769.16 KRH93255.1 - 5.8e-06 26.7 18.0 5.8e-06 26.7 18.0 5.1 3 2 1 4 4 4 1 Divalent cation transporter Nodulin_late PF07127.11 KRH93255.1 - 5.1 7.5 6.9 8.6 6.8 0.9 3.2 1 1 1 2 2 2 0 Late nodulin protein PPIP5K2_N PF18086.1 KRH93256.1 - 0.044 13.9 0.1 0.051 13.7 0.1 1.1 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain UCH PF00443.29 KRH93260.1 - 9.5e-06 25.3 3.2 2.3e-05 24.1 3.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM_X2 PF03442.14 KRH93261.1 - 0.043 13.9 0.2 0.073 13.2 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 MMtag PF10159.9 KRH93261.1 - 7.8 6.9 8.5 2.2 8.6 5.1 1.9 2 1 0 2 2 2 0 Multiple myeloma tumor-associated Glyco_hydro_19 PF00182.19 KRH93262.1 - 4.1e-22 79.2 0.1 1.2e-18 67.8 0.1 2.4 1 1 1 2 2 2 2 Chitinase class I Zn_ribbon_recom PF13408.6 KRH93263.1 - 0.011 16.3 0.4 0.014 15.9 0.4 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.13 KRH93263.1 - 0.034 13.8 0.2 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DDE_3 PF13358.6 KRH93264.1 - 1.8e-25 89.4 0.0 2.3e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KRH93264.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Helicase_C PF00271.31 KRH93266.1 - 5.1e-12 46.1 0.2 4e-11 43.2 0.2 2.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec63 PF02889.16 KRH93266.1 - 2.6e-11 43.2 10.5 1.8e-07 30.6 5.5 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KRH93266.1 - 9.1e-09 35.3 0.0 5.7e-05 23.0 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Dynamin_M PF01031.20 KRH93267.1 - 4.1e-69 232.9 1.6 4.1e-69 232.9 1.6 2.3 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KRH93267.1 - 4.4e-46 157.0 2.5 4.4e-46 157.0 2.5 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KRH93267.1 - 7.1e-20 71.0 1.5 7.1e-20 71.0 1.5 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KRH93267.1 - 1.2e-05 25.3 1.4 5.9e-05 23.1 1.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KRH93267.1 - 0.056 13.7 0.6 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TUG-UBL1 PF11470.8 KRH93267.1 - 0.091 13.0 0.2 0.27 11.5 0.1 1.9 2 0 0 2 2 2 0 TUG ubiquitin-like domain zf-C2H2_aberr PF17017.5 KRH93269.1 - 7.4e-41 140.2 18.2 1.2e-23 84.2 4.1 3.4 3 0 0 3 3 3 2 Aberrant zinc-finger EF-hand_like PF09279.11 KRH93269.1 - 0.018 15.5 1.2 0.22 12.0 0.2 2.9 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Peptidase_S49_N PF08496.10 KRH93269.1 - 0.12 12.4 0.6 0.46 10.5 0.6 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-C2H2_jaz PF12171.8 KRH93269.1 - 0.31 11.4 4.9 0.61 10.4 1.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4446 PF14584.6 KRH93270.1 - 0.011 15.7 1.6 0.011 15.7 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Hira PF07569.11 KRH93271.1 - 0.61 9.8 5.0 0.19 11.4 0.4 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split GCS PF03074.16 KRH93272.1 - 2.8e-71 240.8 15.0 4.7e-69 233.5 15.0 2.7 1 1 0 1 1 1 1 Glutamate-cysteine ligase Ndr PF03096.14 KRH93272.1 - 0.047 12.4 2.6 0.51 9.0 0.2 2.9 2 1 1 3 3 3 0 Ndr family Sugar_tr PF00083.24 KRH93273.1 - 7.7e-33 114.0 34.2 1.4e-23 83.5 9.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KRH93273.1 - 7.8e-18 64.5 27.3 3.3e-17 62.4 8.1 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily Fibrillarin PF01269.17 KRH93274.1 - 6.6e-104 346.0 0.0 7.9e-104 345.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KRH93274.1 - 0.0045 16.7 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KRH93274.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KRH93274.1 - 0.054 13.6 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KRH93274.1 - 0.11 12.2 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF4233 PF14017.6 KRH93276.1 - 0.85 10.0 5.8 2.5 8.5 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4233) Cpn60_TCP1 PF00118.24 KRH93277.1 - 4.1e-129 431.4 7.6 4.7e-129 431.2 7.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3155 PF11352.8 KRH93277.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) Zip PF02535.22 KRH93278.1 - 0.00079 18.7 0.1 0.0014 17.9 0.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Otopetrin PF03189.13 KRH93278.1 - 0.0013 17.6 0.7 0.0017 17.2 0.1 1.4 1 1 0 1 1 1 1 Otopetrin Shisa PF13908.6 KRH93278.1 - 0.0067 16.7 0.4 0.0067 16.7 0.4 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator SpoIIM PF01944.17 KRH93278.1 - 0.01 15.9 0.5 0.02 15.0 0.5 1.6 1 1 0 1 1 1 0 Stage II sporulation protein M DUF1700 PF08006.11 KRH93278.1 - 0.017 14.7 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4337 PF14235.6 KRH93278.1 - 0.026 14.7 0.2 0.041 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DHHC PF01529.20 KRH93278.1 - 0.044 13.9 0.2 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF913 PF06025.12 KRH93278.1 - 0.074 12.0 1.8 0.095 11.7 1.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pal1 PF08316.11 KRH93278.1 - 0.13 13.0 2.8 0.2 12.4 2.8 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Sigma_reg_N PF13800.6 KRH93278.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.8 3 1 0 3 3 3 0 Sigma factor regulator N-terminal DUF4702 PF15774.5 KRH93278.1 - 0.33 9.8 4.4 0.45 9.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) RP-C_C PF11800.8 KRH93278.1 - 0.57 10.2 2.2 0.82 9.7 2.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Rtf2 PF04641.12 KRH93278.1 - 0.61 9.4 10.2 0.96 8.8 10.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Vpu PF00558.19 KRH93278.1 - 1.3 8.9 5.5 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Vpu protein Orf78 PF06024.12 KRH93278.1 - 3 8.2 10.9 0.86 9.9 6.1 2.5 2 1 0 2 2 1 0 Orf78 (ac78) CytochromB561_N PF09786.9 KRH93278.1 - 3.6 6.5 9.6 1.7 7.6 5.7 1.8 1 1 1 2 2 2 0 Cytochrome B561, N terminal DUF4711 PF15829.5 KRH93278.1 - 5.4 6.9 8.7 0.24 11.3 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) HCO3_cotransp PF00955.21 KRH93278.1 - 5.9 5.6 7.1 20 3.8 7.2 1.7 1 1 0 1 1 1 0 HCO3- transporter family LYRIC PF15686.5 KRH93278.1 - 9 5.7 19.4 14 5.1 19.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Asp_protease_2 PF13650.6 KRH93280.1 - 0.0013 19.3 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease eIF3g PF12353.8 KRH93280.1 - 0.0019 18.6 0.7 0.0019 18.6 0.7 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Retrotrans_gag PF03732.17 KRH93280.1 - 0.0051 17.0 0.2 2.4 8.5 0.0 2.7 1 1 1 2 2 2 2 Retrotransposon gag protein gag-asp_proteas PF13975.6 KRH93280.1 - 0.0088 16.6 0.0 0.052 14.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KRH93280.1 - 0.028 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3884 PF13024.6 KRH93280.1 - 0.83 9.3 3.7 2.9 7.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3884) RT_RNaseH PF17917.1 KRH93282.1 - 1.2e-29 102.6 0.0 2.1e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93282.1 - 9.1e-29 100.6 0.8 1.6e-28 99.8 0.8 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93282.1 - 9.8e-27 92.9 0.0 1.7e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH93282.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain HTH_32 PF13565.6 KRH93284.1 - 0.00015 22.3 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.18 KRH93284.1 - 0.002 18.0 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 KRH93284.1 - 0.0054 16.9 0.2 0.081 13.2 0.0 2.7 2 1 1 3 3 3 1 Transposase Rod_C PF10493.9 KRH93284.1 - 0.13 10.6 0.7 0.21 9.9 0.7 1.4 1 1 0 1 1 1 0 Rough deal protein C-terminal region RVT_1 PF00078.27 KRH93285.1 - 1.5e-27 96.6 0.1 1.9e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PTR PF12789.7 KRH93286.1 - 0.053 13.6 1.2 0.13 12.3 1.2 1.7 1 0 0 1 1 1 0 Phage tail repeat like RVT_1 PF00078.27 KRH93289.1 - 3.8e-27 95.2 1.8 8.1e-27 94.2 1.8 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH93289.1 - 6.7e-27 93.8 0.9 3.5e-26 91.5 0.1 2.7 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93289.1 - 2.5e-25 88.4 0.0 8.5e-25 86.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KRH93289.1 - 4.4e-06 27.2 0.0 1.3e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_thumb PF06817.14 KRH93289.1 - 7.7e-05 22.5 0.2 0.00026 20.8 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVP PF00077.20 KRH93289.1 - 0.00066 19.9 0.0 0.0029 17.9 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93289.1 - 0.0028 18.3 0.0 0.011 16.4 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH93289.1 - 0.011 15.5 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease TUTF7_u4 PF16631.5 KRH93289.1 - 0.11 13.2 0.1 0.11 13.2 0.1 4.7 5 0 0 5 5 5 0 Unstructured region 4 on terminal uridylyltransferase 7 GAGA_bind PF06217.12 KRH93291.1 - 0.093 13.0 4.1 0.11 12.7 4.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ureide_permease PF07168.11 KRH93291.1 - 1.4 7.6 4.6 0.73 8.5 2.7 1.4 1 1 0 1 1 1 0 Ureide permease Spt5_N PF11942.8 KRH93291.1 - 4.6 8.3 13.5 1.4 9.9 9.5 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Proteasome PF00227.26 KRH93292.1 - 1.3e-18 67.2 0.0 3e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KRH93292.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Syntaxin_2 PF14523.6 KRH93292.1 - 0.7 10.3 5.0 0.39 11.1 0.5 2.5 3 0 0 3 3 3 0 Syntaxin-like protein Brix PF04427.18 KRH93293.1 - 2.4e-11 44.1 0.2 3e-11 43.8 0.2 1.1 1 0 0 1 1 1 1 Brix domain gag-asp_proteas PF13975.6 KRH93295.1 - 6.6e-07 29.8 0.1 9e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KRH93295.1 - 0.00024 20.9 0.1 0.00032 20.5 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KRH93295.1 - 0.016 15.8 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 KRH93295.1 - 0.025 14.3 0.6 0.034 13.9 0.6 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 KRH93295.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease LAS2 PF15792.5 KRH93296.1 - 0.05 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Lung adenoma susceptibility protein 2 SP24 PF16504.5 KRH93296.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus Rad51 PF08423.11 KRH93297.1 - 4.7e-127 422.5 0.2 2.1e-126 420.4 0.0 1.8 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 KRH93297.1 - 1.6e-08 34.4 0.0 2.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KRH93297.1 - 4.9e-08 32.8 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KRH93297.1 - 2.8e-07 31.0 0.4 1.1e-06 29.2 0.4 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KRH93297.1 - 9.2e-06 25.2 0.1 1.7e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.6 KRH93297.1 - 0.037 14.3 0.1 0.099 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF3173 PF11372.8 KRH93297.1 - 0.063 13.2 0.1 0.2 11.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) RNA_pol_A_CTD PF03118.15 KRH93297.1 - 0.086 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain KH_1 PF00013.29 KRH93299.1 - 0.00017 21.4 0.9 0.00031 20.5 0.9 1.5 1 0 0 1 1 1 1 KH domain Nse4_C PF08743.10 KRH93299.1 - 0.043 14.1 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Nse4 C-terminal DUF2660 PF10859.8 KRH93301.1 - 0.47 10.9 6.4 2.1 8.9 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2660) Flocculin PF00624.18 KRH93303.1 - 0.049 13.9 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Flocculin repeat DegQ PF08181.11 KRH93303.1 - 0.14 12.3 2.1 6.5 6.9 0.7 2.5 2 0 0 2 2 2 0 DegQ (SacQ) family CBFD_NFYB_HMF PF00808.23 KRH93304.1 - 3.8e-06 27.1 0.7 1.8e-05 24.9 0.7 2.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acetyltransf_1 PF00583.25 KRH93305.1 - 8.6e-07 29.2 0.1 1.4e-06 28.5 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRH93305.1 - 6.1e-06 26.6 0.2 1e-05 25.8 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KRH93305.1 - 5e-05 23.2 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KRH93305.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Clenterotox PF03505.14 KRH93305.1 - 0.065 12.8 3.3 0.13 11.8 2.2 2.0 2 1 0 2 2 2 0 Clostridium enterotoxin RT_RNaseH PF17917.1 KRH93307.1 - 5.1e-22 78.1 0.5 5.7e-22 78.0 0.5 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93307.1 - 3.6e-12 46.2 0.3 5.9e-12 45.5 0.1 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Methyltransf_32 PF13679.6 KRH93307.1 - 0.028 14.4 0.4 0.028 14.4 0.4 1.3 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_2 PF00152.20 KRH93309.1 - 8.4e-15 54.7 0.0 8.6e-15 54.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KRH93309.1 - 0.015 14.7 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DDE_Tnp_IS1595 PF12762.7 KRH93311.1 - 1.8e-18 67.0 0.1 2.1e-17 63.6 0.0 2.4 3 0 0 3 3 3 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH93311.1 - 0.0034 16.9 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family zf-C4_Topoisom PF01396.19 KRH93311.1 - 0.0039 16.9 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.16 KRH93311.1 - 0.0052 16.8 0.9 0.009 16.0 0.9 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zf-ACC PF17848.1 KRH93311.1 - 0.035 14.2 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain T4_baseplate PF12322.8 KRH93311.1 - 0.06 12.8 0.2 0.084 12.3 0.2 1.4 1 1 0 1 1 1 0 T4 bacteriophage base plate protein zf-ribbon_3 PF13248.6 KRH93311.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain RVT_1 PF00078.27 KRH93312.1 - 4.7e-08 32.8 0.1 7.7e-08 32.1 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLDc_3 PF13918.6 KRH93313.1 - 0.057 13.1 0.4 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 PLD-like domain YolD PF08863.10 KRH93313.1 - 0.21 11.6 4.8 0.4 10.8 0.6 3.6 3 0 0 3 3 3 0 YolD-like protein Helicase_C_2 PF13307.6 KRH93314.1 - 2e-33 116.0 0.0 4.4e-33 114.9 0.0 1.5 1 1 0 1 1 1 1 Helicase C-terminal domain ESP PF16590.5 KRH93314.1 - 0.036 14.3 1.5 0.49 10.7 0.1 2.3 2 0 0 2 2 2 0 Exocrine gland-secreting peptide ArenaCapSnatch PF17296.2 KRH93314.1 - 0.076 12.5 0.1 11 5.4 0.1 2.3 1 1 1 2 2 2 0 Arenavirus cap snatching domain PLDc_3 PF13918.6 KRH93315.1 - 0.053 13.2 0.3 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 PLD-like domain Helicase_C_2 PF13307.6 KRH93316.1 - 1.1e-33 116.8 0.0 2.4e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ESP PF16590.5 KRH93316.1 - 0.052 13.8 1.3 0.49 10.7 0.1 2.3 2 0 0 2 2 2 0 Exocrine gland-secreting peptide ArenaCapSnatch PF17296.2 KRH93316.1 - 0.064 12.7 0.1 4.8 6.6 0.0 2.3 1 1 0 2 2 2 0 Arenavirus cap snatching domain DUF4580 PF15162.6 KRH93317.1 - 0.03 13.9 3.5 0.46 10.1 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4580) Acetyltransf_1 PF00583.25 KRH93318.1 - 6.7e-17 61.8 0.1 7.7e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRH93318.1 - 1.5e-10 41.4 0.1 2e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRH93318.1 - 4.8e-10 39.4 0.0 6.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KRH93318.1 - 1.1e-05 25.3 0.0 4.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KRH93318.1 - 0.00096 19.2 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KRH93318.1 - 0.0016 18.5 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 KRH93318.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ RVP PF00077.20 KRH93320.1 - 1.4e-05 25.3 0.1 2.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease YhfZ_C PF14503.6 KRH93320.1 - 0.0055 16.3 0.1 0.007 15.9 0.1 1.0 1 0 0 1 1 1 1 YhfZ C-terminal domain gag-asp_proteas PF13975.6 KRH93320.1 - 0.024 15.2 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease His_kinase PF06580.13 KRH93320.1 - 0.083 13.2 0.9 0.21 11.9 0.9 1.7 1 1 0 1 1 1 0 Histidine kinase Pkinase PF00069.25 KRH93321.1 - 2e-55 188.0 0.2 2e-55 188.0 0.2 2.6 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93321.1 - 7.5e-36 123.7 0.4 3.9e-35 121.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 KRH93321.1 - 1e-08 34.9 21.9 3.7e-05 23.5 6.8 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KRH93321.1 - 7.1e-08 32.1 0.0 2.1e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Kinase-like HC2 PF07382.11 KRH93321.1 - 6.1 6.9 14.7 2.4 8.2 10.8 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 HATPase_c_3 PF13589.6 KRH93322.1 - 2.6e-11 43.5 0.3 6.9e-11 42.1 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KRH93322.1 - 4.3e-09 36.9 2.3 4.4e-09 36.8 0.6 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5101 PF17031.5 KRH93322.1 - 0.018 15.1 0.0 0.083 13.0 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) HEAT PF02985.22 KRH93323.1 - 0.11 12.9 0.0 1.6 9.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Acetyltransf_1 PF00583.25 KRH93324.1 - 6.2e-10 39.3 0.0 7.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KRH93324.1 - 5.1e-07 29.7 0.1 7.7e-07 29.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KRH93324.1 - 5.5e-06 26.7 0.0 8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KRH93324.1 - 0.0089 16.2 2.3 0.013 15.6 2.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KRH93324.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Myb_DNA-binding PF00249.31 KRH93325.1 - 1.8e-14 53.6 0.3 0.00015 21.9 0.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KRH93325.1 - 8.6e-05 22.7 10.1 0.3 11.4 0.4 4.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain GAGA_bind PF06217.12 KRH93325.1 - 0.032 14.5 27.0 0.1 12.9 7.8 2.3 2 1 0 2 2 2 0 GAGA binding protein-like family Proteasome PF00227.26 KRH93326.1 - 9.8e-23 80.6 0.1 2.5e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 KRH93326.1 - 5.7e-08 32.3 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.7 KRH93326.1 - 0.036 14.0 0.7 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term COG5 PF10392.9 KRH93327.1 - 0.0053 16.9 2.4 0.0053 16.9 2.4 1.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ubiquitin PF00240.23 KRH93328.1 - 2.4e-34 116.9 1.0 4.1e-34 116.2 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KRH93328.1 - 1.5e-16 60.0 0.3 2.4e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 KRH93328.1 - 9.3e-15 54.5 2.4 1.6e-14 53.8 2.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 KRH93328.1 - 1.9e-05 25.0 0.2 0.00018 21.9 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KRH93328.1 - 0.00033 20.7 0.2 0.00079 19.5 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KRH93328.1 - 0.0069 16.7 0.2 0.018 15.3 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KRH93328.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KRH93328.1 - 0.036 14.6 0.3 0.064 13.8 0.2 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain tRNA-synt_2c PF01411.19 KRH93328.1 - 0.048 12.2 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Ubiquitin_4 PF18036.1 KRH93328.1 - 0.13 12.3 0.6 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain CARD PF00619.21 KRH93329.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Caspase recruitment domain FAM110_N PF14161.6 KRH93329.1 - 0.062 13.5 0.0 0.074 13.3 0.0 1.3 1 1 0 1 1 1 0 Centrosome-associated N terminus Sec23_trunk PF04811.15 KRH93331.1 - 2e-34 119.2 0.1 3e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KRH93331.1 - 1.2e-09 37.9 0.1 3.4e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KRH93331.1 - 5.9e-09 36.6 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KRH93331.1 - 1e-08 35.1 6.8 2.5e-08 33.9 6.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KRH93331.1 - 2.7e-06 27.2 0.0 8e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 KRH93331.1 - 0.0051 16.5 2.9 0.011 15.5 2.9 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_S8e PF01201.22 KRH93332.1 - 2.2e-38 131.5 10.1 1.9e-37 128.5 10.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e SPOUT_MTase PF02590.17 KRH93332.1 - 0.49 10.4 4.0 0.96 9.4 3.8 1.7 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase DEAD PF00270.29 KRH93333.1 - 1.7e-07 31.1 0.7 3.6e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH93333.1 - 0.0077 16.2 0.0 0.0077 16.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KRH93333.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5557 PF17712.1 KRH93333.1 - 0.12 12.4 0.1 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5557) GDI PF00996.18 KRH93334.1 - 2.1e-58 197.9 1.1 1.8e-47 161.9 0.7 2.0 1 1 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KRH93334.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain YqgF PF14639.6 KRH93335.1 - 0.074 12.8 0.1 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Antimicrobial_3 PF08025.11 KRH93335.1 - 0.27 11.2 2.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Spider antimicrobial peptide RT_RNaseH PF17917.1 KRH93336.1 - 1.2e-37 128.4 0.3 3.7e-37 126.8 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93336.1 - 9.9e-32 109.0 0.1 3.6e-31 107.2 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93336.1 - 3.2e-29 102.0 0.1 8.4e-29 100.7 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93336.1 - 1.4e-22 80.1 0.0 3.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93336.1 - 3e-13 49.6 0.2 7.5e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 KRH93336.1 - 1.3e-09 38.3 0.2 4.8e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH93336.1 - 2.8e-06 27.8 0.1 8.5e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH93336.1 - 0.00018 21.3 0.4 0.00051 19.8 0.4 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93336.1 - 0.0027 18.3 0.1 0.0082 16.8 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease DDE_Tnp_IS240 PF13610.6 KRH93336.1 - 0.0071 16.6 0.2 0.023 14.9 0.2 1.9 1 0 0 1 1 1 1 DDE domain DUF4939 PF16297.5 KRH93336.1 - 0.0092 15.9 0.1 0.032 14.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) rve_3 PF13683.6 KRH93336.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_thumb PF06817.14 KRH93336.1 - 0.59 10.0 3.0 0.62 10.0 0.0 2.7 3 0 0 3 3 3 0 Reverse transcriptase thumb domain RT_RNaseH_2 PF17919.1 KRH93337.1 - 1.2e-29 102.2 0.1 5.4e-29 100.2 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93337.1 - 1.3e-29 102.5 0.0 4.4e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93337.1 - 9.1e-26 90.7 0.1 9.1e-26 90.7 0.1 3.6 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93337.1 - 3.5e-11 43.3 0.0 6.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 KRH93337.1 - 7.4e-05 23.2 0.0 0.00023 21.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KRH93337.1 - 0.0001 22.2 0.9 0.0001 22.2 0.9 2.1 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.11 KRH93337.1 - 0.0012 18.7 0.1 0.0031 17.3 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93337.1 - 0.0071 17.0 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.6 KRH93337.1 - 0.12 12.2 0.9 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Integrase core domain DNA_pol_E_B PF04042.16 KRH93338.1 - 6.5e-08 32.2 0.8 6.7e-07 28.9 0.8 2.1 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KRH93338.1 - 0.00034 20.7 0.0 0.0021 18.2 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain DUF243 PF03103.17 KRH93338.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF243) Med31 PF05669.12 KRH93339.1 - 3.4e-30 103.9 7.7 3.9e-30 103.7 7.7 1.1 1 0 0 1 1 1 1 SOH1 ING PF12998.7 KRH93340.1 - 0.0003 21.3 2.4 0.00045 20.8 2.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KRH93340.1 - 0.00034 20.4 12.1 0.00034 20.4 10.8 1.7 2 0 0 2 2 2 1 PHD-finger tRNA-synt_1e PF01406.19 KRH93340.1 - 0.017 14.5 1.8 0.021 14.2 1.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SPATA24 PF15175.6 KRH93340.1 - 0.029 14.3 2.6 0.041 13.8 2.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 ORC2 PF04084.14 KRH93341.1 - 1.9e-16 59.9 7.7 2.3e-09 36.6 2.9 3.0 1 1 0 2 2 2 2 Origin recognition complex subunit 2 DDE_Tnp_IS1595 PF12762.7 KRH93343.1 - 1.1e-25 90.4 0.0 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH93343.1 - 1.9e-05 24.3 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family BTB_2 PF02214.22 KRH93344.1 - 0.13 12.7 1.0 0.15 12.4 0.8 1.3 1 1 0 1 1 1 0 BTB/POZ domain Asp_protease_2 PF13650.6 KRH93346.1 - 6.7e-06 26.7 0.0 8e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH93346.1 - 0.0082 16.7 0.0 0.0086 16.6 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH93346.1 - 0.086 12.6 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease PI3_PI4_kinase PF00454.27 KRH93347.1 - 3.7e-29 102.3 9.5 9.3e-28 97.7 0.4 3.2 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KRH93347.1 - 2.3e-09 36.9 0.0 5.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 FATC domain RVT_1 PF00078.27 KRH93348.1 - 7.2e-20 71.5 0.1 8.3e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ndr PF03096.14 KRH93349.1 - 0.098 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family HTH_IclR PF09339.10 KRH93352.1 - 8e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 KRH93352.1 - 0.00096 19.0 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KRH93352.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 KRH93352.1 - 0.0019 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_5 PF01022.20 KRH93352.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_3 PF01381.22 KRH93352.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_36 PF13730.6 KRH93352.1 - 0.055 13.4 0.1 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KRH93352.1 - 0.089 12.4 0.2 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LacI PF00356.21 KRH93352.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family RTP1_C1 PF10363.9 KRH93352.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 RPN1_RPN2_N PF17781.1 KRH93353.1 - 3.2e-08 33.4 4.1 1e-07 31.7 0.3 2.4 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KRH93353.1 - 0.00077 19.4 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KRH93353.1 - 0.025 15.0 0.0 0.025 15.0 0.0 5.1 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Mucin PF01456.17 KRH93353.1 - 4.7 7.2 18.6 13 5.8 18.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein RT_RNaseH_2 PF17919.1 KRH93354.1 - 4.7e-08 33.0 0.0 5.1e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93354.1 - 1.9e-06 28.1 0.0 2.1e-06 28.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93355.1 - 8.4e-09 35.7 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93356.1 - 5.8e-12 45.8 0.0 7.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DUF2130 PF09903.9 KRH93356.1 - 0.0017 17.7 0.2 0.0019 17.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) ApoO PF09769.9 KRH93356.1 - 0.035 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O DASH_Duo1 PF08651.10 KRH93356.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 zf-C2H2 PF00096.26 KRH93358.1 - 0.00011 22.4 0.8 0.00011 22.4 0.8 5.3 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C3HC4 PF00097.25 KRH93358.1 - 0.00019 21.2 7.8 0.00019 21.2 7.8 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.6 KRH93358.1 - 0.00051 20.0 0.6 0.00051 20.0 0.6 3.9 5 1 1 6 6 6 1 C2H2-type zinc finger zf-C3HC4_3 PF13920.6 KRH93358.1 - 0.00072 19.4 7.2 0.00072 19.4 7.2 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 KRH93358.1 - 0.0008 20.0 0.7 0.0008 20.0 0.7 7.0 6 1 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 KRH93358.1 - 0.0064 16.8 1.0 0.0064 16.8 1.0 5.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KRH93358.1 - 0.0071 16.6 1.3 0.0071 16.6 1.3 5.3 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.6 KRH93358.1 - 0.013 15.4 6.3 0.013 15.4 6.3 3.9 3 1 0 3 3 3 0 zinc-RING finger domain Zip PF02535.22 KRH93358.1 - 3 7.0 12.4 7.6 5.6 12.4 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Sugar_tr PF00083.24 KRH93359.1 - 3.1e-24 85.6 42.7 4.8e-18 65.3 18.7 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KRH93359.1 - 2.1e-09 36.8 32.1 2.1e-09 36.8 32.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2407_C PF13373.6 KRH93359.1 - 2.2 8.4 4.3 7.7 6.7 1.5 2.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain TGT PF01702.18 KRH93360.1 - 7.7e-96 321.3 0.5 1.1e-80 271.5 0.4 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase GLTP PF08718.11 KRH93360.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) MSL2-CXC PF16682.5 KRH93360.1 - 0.12 12.5 0.5 0.12 12.5 0.5 2.4 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 CEBP_ZZ PF16366.5 KRH93360.1 - 3.3 8.0 9.7 0.3 11.4 2.8 2.3 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PTR2 PF00854.21 KRH93361.1 - 8.5e-08 31.4 14.6 9.5e-08 31.3 14.0 1.3 1 1 0 1 1 1 1 POT family SNF2_N PF00176.23 KRH93363.1 - 1.8e-60 204.5 3.1 1.8e-60 204.5 3.1 2.8 3 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KRH93363.1 - 1.2e-18 67.4 0.0 1.2e-18 67.4 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93363.1 - 6.5e-13 49.0 0.3 6.5e-13 49.0 0.3 4.2 4 3 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KRH93363.1 - 4.9e-07 29.7 0.0 1.6e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1086 PF06461.11 KRH93363.1 - 0.0032 17.3 0.3 0.0099 15.7 0.3 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Homeodomain PF00046.29 KRH93364.1 - 4.8e-16 58.3 2.4 1.8e-15 56.5 2.4 2.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH93364.1 - 0.012 15.5 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Methyltr_RsmB-F PF01189.17 KRH93365.1 - 2.3e-41 141.6 0.6 2.7e-31 108.8 0.1 2.4 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F CPSF100_C PF13299.6 KRH93365.1 - 0.035 14.3 0.6 0.035 14.3 0.6 2.5 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 KRH93365.1 - 1.2 8.3 10.9 1.8 7.7 2.2 2.4 3 0 0 3 3 3 0 ZIP Zinc transporter Striatin PF08232.12 KRH93365.1 - 2.9 8.5 14.9 0.62 10.6 2.2 2.4 2 0 0 2 2 2 0 Striatin family Rxt3 PF08642.10 KRH93365.1 - 3.2 8.5 8.0 9.5 7.0 0.6 2.7 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 HTH_Tnp_Tc3_2 PF01498.18 KRH93368.1 - 0.13 12.6 0.4 0.55 10.5 0.1 2.1 2 0 0 2 2 2 0 Transposase DOT1 PF08123.13 KRH93368.1 - 0.61 9.6 6.3 0.39 10.2 2.2 2.3 2 1 0 2 2 2 0 Histone methylation protein DOT1 Got1 PF04178.12 KRH93369.1 - 0.0044 17.4 7.8 0.011 16.1 7.8 1.7 1 1 0 1 1 1 1 Got1/Sft2-like family Ilm1 PF10311.9 KRH93369.1 - 0.05 13.3 1.3 0.059 13.0 1.3 1.1 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF2207 PF09972.9 KRH93369.1 - 1.4 7.5 2.9 1.9 7.2 2.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2583 PF10762.9 KRH93369.1 - 9.6 6.7 7.0 7.3 7.1 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) DUF3340 PF11818.8 KRH93370.1 - 0.16 12.2 3.1 0.44 10.7 0.3 2.5 3 0 0 3 3 3 0 C-terminal domain of tail specific protease (DUF3340) Staphylokinase PF02821.16 KRH93370.1 - 0.35 11.3 4.4 4 7.9 0.2 2.5 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family Rad10 PF03834.14 KRH93371.1 - 5.3e-28 97.3 2.0 9.7e-28 96.5 2.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF4125 PF13526.6 KRH93371.1 - 0.025 14.2 0.5 0.042 13.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) VWA_2 PF13519.6 KRH93372.1 - 1.9e-08 34.9 0.3 9.6e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 von Willebrand factor type A domain RAP80_UIM PF18282.1 KRH93372.1 - 0.0023 17.6 1.2 0.0045 16.7 1.2 1.5 1 0 0 1 1 1 1 RAP80 N-terminal ubiquitin interaction motif Arrestin_N PF00339.29 KRH93373.1 - 4.2e-12 46.3 1.4 7.6e-08 32.5 0.4 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KRH93373.1 - 7.1e-05 23.3 3.0 0.15 12.5 0.6 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain IL22 PF14565.6 KRH93373.1 - 0.016 15.5 1.3 0.026 14.8 1.3 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Y_phosphatase PF00102.27 KRH93374.1 - 4.4e-21 75.5 0.3 1.1e-16 61.2 0.3 2.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KRH93374.1 - 6.1e-07 29.3 0.2 2.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KRH93374.1 - 0.00099 19.1 0.0 0.0058 16.6 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KRH93374.1 - 0.009 16.1 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate RT_RNaseH PF17917.1 KRH93375.1 - 8.7e-34 116.0 0.0 3.8e-33 113.9 0.0 2.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93375.1 - 3.2e-31 107.3 0.0 1.7e-30 105.0 0.0 2.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93375.1 - 2e-26 92.9 3.1 2.1e-26 92.9 0.6 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93375.1 - 2.8e-16 59.8 0.0 2.9e-15 56.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93375.1 - 1.4e-10 41.1 1.8 3.1e-10 40.0 1.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KRH93375.1 - 0.002 17.8 1.4 0.0056 16.4 0.3 2.5 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KRH93377.1 - 2.4e-09 37.6 0.0 4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 KRH93377.1 - 2.5e-07 30.4 0.1 4.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 KRH93377.1 - 5.6e-07 30.1 0.0 9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KRH93377.1 - 1.1e-06 28.4 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH93377.1 - 0.0009 19.5 0.1 0.0025 18.1 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 KRH93377.1 - 0.02 14.7 0.2 0.03 14.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.11 KRH93377.1 - 0.043 13.6 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 KRH93378.1 - 1.2e-24 86.5 0.0 1.8e-23 82.8 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93378.1 - 1.4e-24 86.0 0.0 5.2e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93378.1 - 3.6e-21 75.7 0.0 8.4e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93378.1 - 1.7e-16 60.5 0.1 4.1e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93378.1 - 1.5e-11 44.2 3.2 1.5e-11 44.2 3.2 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH93378.1 - 0.0066 16.6 0.2 0.016 15.4 0.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_thumb PF06817.14 KRH93378.1 - 0.013 15.3 0.3 0.048 13.5 0.3 1.9 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Endotoxin_N PF03945.14 KRH93378.1 - 0.032 14.0 0.5 0.066 12.9 0.5 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain rve_3 PF13683.6 KRH93378.1 - 0.096 12.5 1.2 0.77 9.6 0.1 2.8 3 0 0 3 3 3 0 Integrase core domain ADH_N PF08240.12 KRH93378.1 - 0.1 12.5 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF747 PF05346.11 KRH93379.1 - 8e-43 147.1 4.6 1.2e-42 146.5 4.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3552 PF12072.8 KRH93379.1 - 0.2 11.0 3.7 0.32 10.4 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.9 KRH93379.1 - 0.86 9.5 4.9 1.6 8.6 4.9 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3270 PF11674.8 KRH93379.1 - 0.96 9.7 8.9 0.078 13.2 2.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3270) Mis12 PF05859.12 KRH93380.1 - 0.0033 17.5 2.1 1.8 8.6 2.1 2.4 1 1 0 1 1 1 1 Mis12 protein YoeB_toxin PF06769.14 KRH93380.1 - 0.034 14.2 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system HIP1_clath_bdg PF16515.5 KRH93380.1 - 0.57 10.8 5.7 0.37 11.4 1.8 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SR-25 PF10500.9 KRH93381.1 - 0.011 15.4 18.0 0.011 15.4 18.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein A_thal_3526 PF09713.10 KRH93381.1 - 0.031 14.5 2.5 6.1 7.2 0.2 2.7 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) DUF3744 PF12558.8 KRH93381.1 - 0.032 15.0 0.4 0.032 15.0 0.4 3.4 2 2 2 4 4 4 0 ATP-binding cassette cobalt transporter Zip PF02535.22 KRH93381.1 - 0.11 11.8 9.6 0.18 11.0 9.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 KRH93381.1 - 0.28 10.6 15.6 0.58 9.5 15.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hydin_ADK PF17213.3 KRH93381.1 - 0.45 10.8 9.8 0.18 12.1 7.0 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Dsh_C PF12316.8 KRH93381.1 - 1.9 8.9 8.9 2.9 8.2 8.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CCDC106 PF15794.5 KRH93381.1 - 6.4 6.4 26.6 0.18 11.5 19.3 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Peptidase_U57 PF05582.12 KRH93381.1 - 9.8 5.3 17.7 2.7 7.2 7.8 2.1 2 0 0 2 2 2 0 YabG peptidase U57 PIEZO PF15917.5 KRH93382.1 - 0.082 12.4 0.3 0.083 12.4 0.3 1.1 1 0 0 1 1 1 0 Piezo USP7_C2 PF14533.6 KRH93383.1 - 0.028 14.1 0.5 0.029 14.1 0.5 1.0 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DDE_Tnp_IS1595 PF12762.7 KRH93383.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain RT_RNaseH_2 PF17919.1 KRH93384.1 - 2.1e-27 95.1 0.1 4.4e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93384.1 - 1.4e-24 86.4 0.1 3.1e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93384.1 - 1.2e-23 83.8 0.8 2.7e-23 82.7 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93384.1 - 6.9e-17 61.7 0.0 2.8e-16 59.8 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain RVT_thumb PF06817.14 KRH93384.1 - 4.8e-06 26.3 1.8 2.5e-05 24.0 0.1 2.8 3 0 0 3 3 3 1 Reverse transcriptase thumb domain Integrase_H2C2 PF17921.1 KRH93384.1 - 0.00018 21.6 0.9 0.0005 20.1 0.9 1.8 1 1 0 1 1 1 1 Integrase zinc binding domain DNA_pack_C PF02499.15 KRH93384.1 - 0.0016 17.5 0.1 0.0033 16.4 0.1 1.4 1 0 0 1 1 1 1 Probable DNA packing protein, C-terminus RVT_3 PF13456.6 KRH93384.1 - 0.0047 16.7 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like DUF1878 PF08963.10 KRH93384.1 - 0.018 15.6 0.3 0.073 13.6 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) RVP_2 PF08284.11 KRH93385.1 - 5.2e-07 29.5 0.2 1.6e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 KRH93385.1 - 3.8e-06 27.1 0.2 9.7e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH93385.1 - 6.4e-06 26.6 0.0 1.8e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KRH93385.1 - 2.6e-05 24.0 0.1 5.1e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KRH93385.1 - 0.00016 22.3 0.0 0.00056 20.5 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease Elf1 PF05129.13 KRH93386.1 - 0.039 14.0 0.1 0.039 14.0 0.1 2.5 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like AF-4 PF05110.13 KRH93386.1 - 0.11 10.5 18.5 0.13 10.3 18.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RR_TM4-6 PF06459.12 KRH93386.1 - 4 7.2 15.3 5.3 6.8 15.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_20 PF00982.21 KRH93387.1 - 5.1e-61 206.8 0.7 3.9e-18 65.4 0.0 4.2 4 0 0 4 4 4 4 Glycosyltransferase family 20 DUF4769 PF15992.5 KRH93387.1 - 0.0084 15.9 0.9 0.0084 15.9 0.9 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4769) TBPIP PF07106.13 KRH93389.1 - 1.6e-10 40.7 3.0 7.1e-10 38.7 0.5 2.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Mnd1 PF03962.15 KRH93389.1 - 0.038 14.3 0.1 0.038 14.3 0.1 3.1 2 0 0 2 2 2 0 Mnd1 HTH domain Lant_dehydr_N PF04738.13 KRH93389.1 - 0.045 11.8 0.2 0.15 10.1 0.2 1.7 1 1 0 1 1 1 0 Lantibiotic dehydratase, N terminus DUF1192 PF06698.11 KRH93389.1 - 0.21 11.6 8.1 1.5 8.9 1.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Macoilin PF09726.9 KRH93389.1 - 4 5.9 53.1 13 4.2 53.1 1.7 1 1 0 1 1 1 0 Macoilin family Rootletin PF15035.6 KRH93391.1 - 0.00074 19.6 1.7 0.0008 19.5 1.7 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KRH93391.1 - 0.0011 19.0 7.3 0.0014 18.7 7.3 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ETRAMP PF09716.10 KRH93391.1 - 0.0016 18.4 0.2 0.0016 18.4 0.2 1.7 1 1 1 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) FlaC_arch PF05377.11 KRH93391.1 - 0.0034 17.8 5.5 0.08 13.4 1.3 2.3 1 1 1 2 2 2 2 Flagella accessory protein C (FlaC) Rota_NSP4 PF01452.16 KRH93391.1 - 0.0095 15.6 0.7 0.01 15.5 0.7 1.1 1 0 0 1 1 1 1 Rotavirus non structural protein DUF4094 PF13334.6 KRH93391.1 - 0.022 15.1 2.8 0.85 10.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) YpjP PF14005.6 KRH93391.1 - 0.028 14.5 1.0 0.034 14.2 1.0 1.1 1 0 0 1 1 1 0 YpjP-like protein BRI3BP PF14965.6 KRH93391.1 - 0.05 13.1 0.2 0.089 12.3 0.1 1.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 PKHD_C PF18331.1 KRH93391.1 - 0.14 12.3 1.3 0.47 10.6 0.2 2.0 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain Nas2_N PF18265.1 KRH93391.1 - 0.46 10.4 4.8 13 5.8 4.8 2.1 1 1 0 1 1 1 0 Nas2 N_terminal domain DUF4140 PF13600.6 KRH93391.1 - 1.2 9.7 7.2 5.3 7.5 1.6 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GTP-bdg_M PF16360.5 KRH93391.1 - 1.5 9.5 6.1 1 10.0 1.2 2.0 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF1192 PF06698.11 KRH93391.1 - 3.9 7.6 7.0 1.4 9.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) rve PF00665.26 KRH93392.1 - 3.4e-13 49.8 0.0 8.7e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH93392.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 KRH93393.1 - 4e-05 23.5 0.4 7.2e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4897 PF16238.5 KRH93393.1 - 0.0027 17.6 0.4 0.0039 17.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4897) Ribosomal_L7Ae PF01248.26 KRH93395.1 - 4.7e-08 32.7 0.5 5.4e-08 32.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KRH93395.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain CENP-H PF05837.12 KRH93395.1 - 0.014 15.8 1.0 0.018 15.5 1.0 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF241 PF03087.14 KRH93395.1 - 0.02 14.8 1.6 0.023 14.5 1.6 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Acetyltransf_16 PF05301.11 KRH93395.1 - 0.024 14.4 0.5 0.025 14.3 0.5 1.3 1 1 0 1 1 1 0 GNAT acetyltransferase, Mec-17 DUF2574 PF10836.8 KRH93395.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) RT_RNaseH PF17917.1 KRH93398.1 - 5.7e-36 123.0 0.2 1.9e-35 121.3 0.2 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93398.1 - 6.3e-31 106.4 0.0 1.9e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93398.1 - 2.4e-29 102.4 0.2 6.1e-29 101.1 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93398.1 - 2.1e-12 47.3 0.0 6e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93398.1 - 1.1e-10 41.4 0.0 2.7e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 KRH93398.1 - 1.4e-06 28.6 2.0 2.8e-06 27.6 0.2 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease PNMA PF14893.6 KRH93398.1 - 0.0013 18.2 0.5 0.004 16.6 0.4 1.8 2 0 0 2 2 2 1 PNMA Retrotrans_gag PF03732.17 KRH93398.1 - 0.0094 16.2 3.6 0.0098 16.2 1.2 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH PF17917.1 KRH93399.1 - 1.2e-24 86.6 0.0 5.5e-24 84.5 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93399.1 - 4.4e-24 84.4 0.0 9.3e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93399.1 - 2.6e-18 66.3 0.0 2.7e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_thumb PF06817.14 KRH93399.1 - 1.3e-06 28.2 1.5 2.4e-06 27.3 0.4 2.0 2 0 0 2 2 2 1 Reverse transcriptase thumb domain RVT_3 PF13456.6 KRH93399.1 - 4.5e-06 26.5 0.1 1.1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Integrase_H2C2 PF17921.1 KRH93399.1 - 0.00024 21.1 1.7 0.00068 19.7 1.7 1.8 1 1 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KRH93399.1 - 0.14 12.0 0.4 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 KRH93400.1 - 1e-14 54.6 1.9 2.6e-14 53.3 0.0 2.6 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 KRH93400.1 - 1.5e-05 25.5 0.0 4.3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH93400.1 - 0.00023 21.6 0.0 0.00076 20.0 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KRH93400.1 - 0.00029 21.1 0.0 0.0007 19.9 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KRH93400.1 - 0.00099 18.9 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DNA_pol_B_3 PF08408.10 KRH93400.1 - 2 8.6 7.0 1.7 8.9 1.3 3.4 2 2 1 3 3 3 0 DNA polymerase family B viral insert MRP-S32 PF10210.9 KRH93400.1 - 4.4 7.9 6.6 1.3 9.6 0.9 3.0 3 1 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 2OG-FeII_Oxy_3 PF13640.6 KRH93403.1 - 3.3e-12 47.1 0.0 7.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KRH93403.1 - 2.6e-10 40.8 0.1 2.6e-10 40.8 0.1 2.1 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Cdh1_DBD_1 PF18196.1 KRH93403.1 - 0.0092 16.3 0.1 0.025 14.9 0.0 1.7 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 DUF2985 PF11204.8 KRH93404.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) DUF5531 PF17671.1 KRH93404.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) Sec23_trunk PF04811.15 KRH93405.1 - 1.8e-12 47.4 0.1 6.6e-12 45.5 0.1 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KRH93405.1 - 0.0024 18.6 0.1 0.051 14.3 0.1 2.5 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KRH93405.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Gelsolin repeat Ninjurin PF04923.12 KRH93406.1 - 0.031 14.2 5.3 1.6 8.7 1.7 2.5 2 0 0 2 2 2 0 Ninjurin FA_desaturase PF00487.24 KRH93406.1 - 1.9 8.2 5.8 1.5 8.6 4.7 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Nsp1_C PF05064.13 KRH93408.1 - 0.0031 17.3 1.4 0.0031 17.3 1.4 2.8 3 0 0 3 3 3 1 Nsp1-like C-terminal region DUF5446 PF17522.2 KRH93408.1 - 0.024 14.8 0.5 0.024 14.8 0.5 3.5 1 1 1 3 3 3 0 Family of unknown function (DUF5446) DUF4358 PF14270.6 KRH93408.1 - 0.029 14.7 0.5 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Nop PF01798.18 KRH93408.1 - 0.087 12.3 2.9 0.2 11.1 2.0 1.9 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin TFX_C PF14601.6 KRH93408.1 - 0.099 12.6 0.3 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term UPF0449 PF15136.6 KRH93408.1 - 0.12 12.8 4.7 0.23 12.0 1.4 2.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Keratin_B2 PF01500.17 KRH93408.1 - 0.13 12.2 1.1 0.19 11.7 1.1 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein FapA PF03961.13 KRH93408.1 - 0.29 9.7 5.9 0.28 9.7 4.7 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Sec20 PF03908.13 KRH93408.1 - 2.7 8.0 9.4 0.071 13.0 1.0 2.5 3 1 0 3 3 3 0 Sec20 CCP_MauG PF03150.14 KRH93408.1 - 4.2 8.0 8.0 22 5.7 8.0 2.1 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase TFIIA PF03153.13 KRH93408.1 - 5.4 6.9 17.6 6.6 6.6 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF16 PF01519.16 KRH93408.1 - 5.5 7.5 8.9 4.5 7.8 5.6 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Sec8_exocyst PF04048.14 KRH93408.1 - 6 6.7 9.7 0.42 10.5 0.8 2.7 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Tyrosinase PF00264.20 KRH93408.1 - 6.4 7.0 11.3 4 7.7 9.0 1.8 1 1 1 2 2 2 0 Common central domain of tyrosinase SelK_SelG PF10961.8 KRH93409.1 - 0.96 10.1 3.6 0.72 10.5 0.1 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DDE_Tnp_IS1595 PF12762.7 KRH93411.1 - 0.001 19.1 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DNA_ligase_ZBD PF03119.16 KRH93412.1 - 8.7e-05 22.5 0.6 0.00012 22.0 0.6 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain T4_baseplate PF12322.8 KRH93412.1 - 0.00079 19.0 0.3 0.00085 18.9 0.3 1.1 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.19 KRH93412.1 - 0.0017 18.1 2.3 0.0029 17.3 2.3 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 KRH93412.1 - 0.015 14.7 0.5 0.034 13.6 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 KRH93412.1 - 0.016 15.2 0.2 0.033 14.3 0.2 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Elf1 PF05129.13 KRH93412.1 - 0.03 14.3 0.2 0.036 14.1 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like NAP PF00956.18 KRH93414.1 - 0.0028 16.9 8.2 0.0047 16.1 0.8 2.6 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Ricin_B_lectin PF00652.22 KRH93415.1 - 7.3e-06 26.3 0.0 1.8e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KRH93415.1 - 0.00046 20.8 0.0 0.0061 17.3 0.0 2.5 1 1 2 3 3 3 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KRH93415.1 - 0.011 15.3 1.7 0.026 14.1 1.2 2.0 1 1 0 1 1 1 0 Cytolethal distending toxin A/C domain vATP-synt_E PF01991.18 KRH93416.1 - 0.009 15.4 5.2 0.01 15.2 5.2 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Patatin PF01734.22 KRH93418.1 - 1.8e-08 34.8 0.0 1.2e-07 32.1 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DZR PF12773.7 KRH93418.1 - 0.16 12.0 1.4 0.36 10.9 1.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon adh_short PF00106.25 KRH93419.1 - 1.9e-34 118.8 0.0 2.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KRH93419.1 - 3.2e-19 69.4 0.0 5.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KRH93419.1 - 3.4e-05 23.8 0.1 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KRH93419.1 - 0.0031 17.2 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 KRH93419.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KRH93419.1 - 0.034 13.3 0.4 0.087 11.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KRH93419.1 - 0.079 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Wax2_C PF12076.8 KRH93419.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain dCMP_cyt_deam_1 PF00383.23 KRH93420.1 - 2.2e-23 82.0 0.1 3.5e-23 81.4 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KRH93420.1 - 1.2e-13 51.0 0.0 2.6e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Helicase_C PF00271.31 KRH93421.1 - 4.4e-19 68.9 0.3 9.8e-19 67.7 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF5321 PF17254.2 KRH93421.1 - 0.061 12.8 4.5 0.082 12.3 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Nucleoporin_FG PF13634.6 KRH93422.1 - 2.1 9.3 11.1 8.8 7.2 11.1 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region Pannexin_like PF12534.8 KRH93422.1 - 3.1 6.8 9.6 5.1 6.1 9.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Zip PF02535.22 KRH93422.1 - 4.4 6.4 6.4 6.3 5.9 6.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CHY PF05495.12 KRH93423.1 - 3.4e-09 37.1 11.6 3.4e-09 37.1 11.6 3.8 3 1 1 4 4 4 2 CHY zinc finger GvpK PF05121.12 KRH93424.1 - 0.0012 18.8 1.3 0.0025 17.8 1.3 1.5 1 0 0 1 1 1 1 Gas vesicle protein K KLRAQ PF10205.9 KRH93424.1 - 0.0045 17.2 6.8 0.0045 17.2 6.8 1.5 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein HALZ PF02183.18 KRH93424.1 - 0.0053 17.0 1.3 0.014 15.7 0.4 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF1640 PF07798.11 KRH93424.1 - 0.0078 16.3 3.5 0.012 15.6 3.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 KRH93424.1 - 0.023 14.1 0.3 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IL11 PF07400.11 KRH93424.1 - 0.045 13.4 2.0 0.11 12.1 2.0 1.7 1 1 0 1 1 1 0 Interleukin 11 DUF3782 PF12644.7 KRH93424.1 - 0.099 12.8 0.4 0.28 11.4 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) bZIP_1 PF00170.21 KRH93424.1 - 0.77 9.9 10.2 0.12 12.5 3.1 2.6 2 1 1 3 3 3 0 bZIP transcription factor DUF4268 PF14088.6 KRH93424.1 - 1.8 8.5 9.5 0.32 10.8 6.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) YabA PF06156.13 KRH93424.1 - 2.5 8.8 11.7 1 10.0 8.5 2.1 2 1 0 2 2 2 0 Initiation control protein YabA IFP_35_N PF07334.13 KRH93424.1 - 3.4 7.8 9.3 0.87 9.7 4.9 2.2 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_MLP1_2 PF07926.12 KRH93424.1 - 9.9 6.2 14.4 0.2 11.7 7.4 1.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein ERO1 PF04137.15 KRH93425.1 - 3e-18 66.1 10.8 2.3e-15 56.7 5.4 3.3 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) AAA PF00004.29 KRH93426.1 - 1.2e-44 152.0 0.0 2.2e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH93426.1 - 8.5e-11 41.5 0.1 2.4e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KRH93426.1 - 7.3e-07 29.3 0.1 3.8e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KRH93426.1 - 8.1e-06 26.1 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KRH93426.1 - 8.9e-06 26.0 0.2 0.0064 16.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KRH93426.1 - 1.3e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KRH93426.1 - 4e-05 24.1 0.1 0.0014 19.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KRH93426.1 - 0.00025 20.8 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KRH93426.1 - 0.0012 18.4 0.0 0.0039 16.7 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KRH93426.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRH93426.1 - 0.0015 19.1 0.0 0.0036 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KRH93426.1 - 0.0021 18.4 0.0 0.0087 16.4 0.0 2.0 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KRH93426.1 - 0.0033 16.8 0.1 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KRH93426.1 - 0.0043 17.2 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KRH93426.1 - 0.0061 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 KRH93426.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH93426.1 - 0.0066 16.4 0.1 0.63 9.9 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KRH93426.1 - 0.0066 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 KRH93426.1 - 0.0082 15.9 0.3 0.031 14.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KRH93426.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KRH93426.1 - 0.028 14.4 0.0 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KRH93426.1 - 0.036 13.4 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 KRH93426.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 KRH93426.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 KRH93426.1 - 0.058 13.8 0.0 0.23 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRH93426.1 - 0.089 13.3 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 KRH93426.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KRH93426.1 - 0.1 12.1 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KRH93426.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KRH93426.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KRH93426.1 - 0.14 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KRH93426.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain LSM PF01423.22 KRH93427.1 - 1.4e-15 56.8 0.4 1.4e-15 56.8 0.4 1.4 2 0 0 2 2 2 1 LSM domain Prefoldin PF02996.17 KRH93428.1 - 0.00082 19.3 0.4 0.00096 19.1 0.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit G_glu_transpept PF01019.21 KRH93429.1 - 1.1e-143 479.8 0.0 1.2e-143 479.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 KRH93430.1 - 3.3e-25 88.9 0.2 1.1e-12 47.9 0.1 3.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93430.1 - 5.9e-14 52.0 0.3 2.7e-07 30.2 0.0 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KRH93430.1 - 0.00043 19.7 1.2 0.0053 16.1 0.1 2.8 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KRH93430.1 - 0.0009 18.1 0.2 0.0011 17.8 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KRH93430.1 - 0.0017 17.8 0.3 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KRH93430.1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ALMS_repeat PF18727.1 KRH93430.1 - 0.078 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Sua5_yciO_yrdC PF01300.18 KRH93431.1 - 1.3e-31 109.4 0.0 3.7e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 Telomere recombination SUA5 PF03481.13 KRH93431.1 - 2.7e-11 44.1 0.0 7.3e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Tautomerase_3 PF14832.6 KRH93432.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative oxalocrotonate tautomerase enzyme PRK PF00485.18 KRH93434.1 - 1.1e-16 61.2 1.3 8e-11 42.0 0.0 2.4 3 0 0 3 3 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KRH93434.1 - 8.9e-07 29.5 0.1 2.8e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KRH93434.1 - 1.4e-06 28.8 0.0 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KRH93434.1 - 5.5e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KRH93434.1 - 1.8e-05 24.6 0.0 5.2e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase IstB_IS21 PF01695.17 KRH93434.1 - 2.6e-05 24.0 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein CPT PF07931.12 KRH93434.1 - 2.9e-05 24.0 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KRH93434.1 - 6.3e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 KRH93434.1 - 9.2e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRH93434.1 - 0.00017 21.6 0.2 0.0029 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KRH93434.1 - 0.00029 21.1 0.0 0.00073 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH93434.1 - 0.0021 18.0 0.9 0.0051 16.8 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Dna2 PF08696.11 KRH93434.1 - 0.0029 17.4 1.4 0.0049 16.7 0.0 1.9 2 1 0 2 2 2 1 DNA replication factor Dna2 KTI12 PF08433.10 KRH93434.1 - 0.0034 16.9 0.9 0.005 16.3 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 KRH93434.1 - 0.0052 16.7 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase T2SSE PF00437.20 KRH93434.1 - 0.0056 15.8 0.5 0.01 15.0 0.3 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 KRH93434.1 - 0.0071 16.7 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KRH93434.1 - 0.0077 16.7 0.1 0.0077 16.7 0.1 2.9 1 1 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KRH93434.1 - 0.0087 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 KRH93434.1 - 0.013 15.0 0.2 0.013 15.0 0.2 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 KRH93434.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 KRH93434.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KRH93434.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRH93434.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 KRH93434.1 - 0.088 11.5 0.0 0.088 11.5 0.0 2.1 1 1 1 2 2 2 0 RNA12 protein Torsin PF06309.11 KRH93434.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Torsin TT_ORF1 PF02956.14 KRH93434.1 - 0.89 8.1 6.5 1.4 7.5 6.5 1.3 1 0 0 1 1 1 0 TT viral orf 1 Hydin_ADK PF17213.3 KRH93434.1 - 2 8.7 0.0 2 8.7 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain PUA PF01472.20 KRH93435.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 KRH93435.1 - 0.86 10.3 2.6 27 5.6 1.4 2.8 2 1 0 2 2 2 0 Pre-PUA-like domain Glutaredoxin PF00462.24 KRH93436.1 - 5.6e-10 39.3 0.0 1.6e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 KRH93436.1 - 0.0047 17.1 1.0 0.0071 16.5 0.1 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein P-mevalo_kinase PF04275.14 KRH93436.1 - 0.056 13.4 2.7 0.069 13.1 0.7 1.9 1 1 0 2 2 2 0 Phosphomevalonate kinase IL2 PF00715.17 KRH93436.1 - 0.15 12.0 3.1 0.58 10.1 1.2 2.1 1 1 1 2 2 2 0 Interleukin 2 Hexapep PF00132.24 KRH93438.1 - 5.5e-06 25.9 2.0 0.00013 21.6 0.4 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KRH93438.1 - 0.64 9.8 5.7 2.7 7.8 0.2 2.9 1 1 2 3 3 2 0 Hexapeptide repeat of succinyl-transferase DDE_Tnp_1_7 PF13843.6 KRH93439.1 - 1.8e-21 76.8 1.4 2.1e-21 76.6 1.4 1.0 1 0 0 1 1 1 1 Transposase IS4 rve PF00665.26 KRH93440.1 - 1.4e-07 31.8 0.1 1.6e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain Histone PF00125.24 KRH93441.1 - 9.5e-30 103.6 6.1 1.1e-29 103.5 6.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KRH93441.1 - 2e-05 24.6 1.1 4.4e-05 23.6 0.1 1.9 1 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KRH93441.1 - 0.00024 21.3 1.4 0.00043 20.5 0.0 2.1 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KRH93441.1 - 0.00025 21.4 0.0 0.00054 20.3 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KRH93441.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PAF PF15715.5 KRH93441.1 - 0.0064 17.1 0.4 0.0064 17.1 0.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Nrap_D4 PF17405.2 KRH93442.1 - 0.044 13.1 0.3 0.29 10.5 0.0 2.3 2 0 0 2 2 2 0 Nrap protein nucleotidyltransferase domain 4 zf-CCCH_4 PF18044.1 KRH93443.1 - 6.6e-09 35.4 0.8 6.6e-09 35.4 0.8 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KRH93443.1 - 6.2e-07 29.3 2.6 6.2e-07 29.3 2.6 3.0 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 KRH93443.1 - 7.5e-06 25.7 9.6 1.1e-05 25.2 0.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KRH93443.1 - 0.0012 19.1 3.5 0.0012 19.1 3.5 1.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KRH93443.1 - 0.0026 18.1 1.6 0.0026 18.1 1.6 2.5 2 1 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KRH93443.1 - 0.0069 17.1 1.5 0.0069 17.1 1.5 2.0 1 1 1 2 2 2 1 Torus domain DapH_N PF08503.10 KRH93444.1 - 0.052 13.8 3.1 0.1 12.8 2.6 1.8 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal G10 PF01125.17 KRH93445.1 - 2.1e-27 95.7 7.4 2.5e-27 95.4 7.4 1.2 1 0 0 1 1 1 1 G10 protein PEMT PF04191.13 KRH93446.1 - 0.1 13.0 6.0 0.051 14.0 1.6 2.3 2 1 0 2 2 2 0 Phospholipid methyltransferase Evr1_Alr PF04777.13 KRH93447.1 - 3e-24 85.4 0.1 7.2e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Erv1 / Alr family ABC1 PF03109.16 KRH93448.1 - 1.2e-13 51.3 0.2 8.3e-13 48.5 0.2 2.2 1 1 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KRH93448.1 - 2.2e-09 37.1 6.6 9.4e-08 31.7 4.8 2.7 1 1 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KRH93448.1 - 3.9e-07 29.8 2.4 6.6e-07 29.1 0.6 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KRH93448.1 - 1.9e-06 27.3 1.6 9.4e-06 25.1 0.5 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KRH93448.1 - 0.0049 16.8 0.0 0.031 14.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 KRH93449.1 - 1e-29 103.6 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Tox-MPTase2 PF15638.6 KRH93449.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Cons_hypoth95 PF03602.15 KRH93449.1 - 0.013 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.19 KRH93449.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase La PF05383.17 KRH93450.1 - 1.6e-13 50.5 0.1 4.9e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KRH93450.1 - 8.1e-06 25.6 0.1 8.1e-06 25.6 0.1 2.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.16 KRH93450.1 - 0.021 14.9 1.2 0.029 14.4 0.2 1.9 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family RVT_1 PF00078.27 KRH93454.1 - 1.8e-18 66.9 3.7 9.3e-13 48.2 0.5 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 KRH93454.1 - 3e-16 59.7 12.0 4.2e-16 59.3 7.7 2.7 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain LCAT PF02450.15 KRH93455.1 - 5.2e-25 88.4 0.1 6e-13 48.7 0.0 3.1 2 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 KRH93455.1 - 4.3e-07 29.9 0.0 0.00073 19.3 0.0 3.2 4 0 0 4 4 4 2 PGAP1-like protein Hydrolase_4 PF12146.8 KRH93455.1 - 0.00054 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KRH93455.1 - 0.0038 17.9 0.0 0.0065 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KRH93455.1 - 0.016 14.7 2.2 1.6 8.2 0.0 3.2 3 1 0 3 3 3 0 Putative serine esterase (DUF676) DUF900 PF05990.12 KRH93455.1 - 0.034 13.6 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1411 PF07199.11 KRH93457.1 - 0.032 13.9 0.8 0.032 13.9 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) DUF1199 PF06712.11 KRH93458.1 - 0.085 12.9 2.2 43 4.2 0.0 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1199) Ribosomal_L7Ae PF01248.26 KRH93459.1 - 3.4e-23 81.2 0.5 6.6e-23 80.3 0.3 1.6 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KRH93459.1 - 0.0018 18.4 0.1 0.0022 18.1 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 mCpol PF18182.1 KRH93460.1 - 7 7.0 9.3 0.15 12.4 0.4 2.9 4 0 0 4 4 4 0 minimal CRISPR polymerase domain rve PF00665.26 KRH93461.1 - 2.7e-08 34.0 0.0 3.5e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH93461.1 - 0.0032 17.2 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RWP-RK PF02042.15 KRH93461.1 - 1.1 9.3 0.1 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 RWP-RK domain RT_RNaseH_2 PF17919.1 KRH93462.1 - 4.3e-30 103.7 0.0 4.8e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93462.1 - 8.6e-27 93.5 0.0 9.8e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Peptidase_A17 PF05380.13 KRH93462.1 - 0.08 12.9 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Pao retrotransposon peptidase zf-CCHC PF00098.23 KRH93463.1 - 2.1e-05 24.4 2.6 3.1e-05 23.8 2.6 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH93463.1 - 0.0057 16.4 0.9 0.0057 16.4 0.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CHC2 PF01807.20 KRH93463.1 - 0.021 14.6 0.4 0.029 14.2 0.4 1.2 1 0 0 1 1 1 0 CHC2 zinc finger zf-CCHC_6 PF15288.6 KRH93463.1 - 0.12 12.2 0.9 0.21 11.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Sec16_C PF12931.7 KRH93465.1 - 0.094 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 SRP54 PF00448.22 KRH93465.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain IRK PF01007.20 KRH93466.1 - 0.085 12.7 0.6 0.086 12.6 0.6 1.0 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Actin PF00022.19 KRH93468.1 - 2.4e-09 36.3 0.0 5.1e-08 31.9 0.0 2.4 1 1 0 1 1 1 1 Actin HTH_38 PF13936.6 KRH93468.1 - 0.011 15.4 0.5 0.3 10.9 0.3 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ORC_WH_C PF18137.1 KRH93468.1 - 0.28 11.3 12.5 10 6.2 0.1 3.3 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal DUF4770 PF15994.5 KRH93468.1 - 0.55 10.5 10.3 1.3 9.2 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) POX PF07526.11 KRH93468.1 - 3.6 8.2 10.9 2.4 8.7 6.2 2.4 2 0 0 2 2 2 0 Associated with HOX TMEMspv1-c74-12 PF11044.8 KRH93469.1 - 0.033 14.2 1.2 0.2 11.7 0.1 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CoatB PF10389.9 KRH93469.1 - 0.079 12.8 1.4 0.14 12.0 1.4 1.3 1 0 0 1 1 1 0 Bacteriophage coat protein B Vpu PF00558.19 KRH93469.1 - 0.089 12.6 0.9 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Vpu protein tRNA-synt_2b PF00587.25 KRH93471.1 - 2.4e-32 112.4 0.0 9e-30 104.0 0.0 2.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KRH93471.1 - 7.2e-15 54.9 0.2 1.6e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KRH93471.1 - 8.8e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain INT_SG_DDX_CT_C PF15300.6 KRH93471.1 - 0.0051 16.6 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus YodL PF14191.6 KRH93471.1 - 0.006 17.4 0.9 0.4 11.5 0.2 2.8 2 0 0 2 2 2 1 YodL-like Fibin PF15819.5 KRH93472.1 - 0.036 13.8 1.1 0.036 13.8 1.1 2.2 2 0 0 2 2 2 0 Fin bud initiation factor homologue DER1 PF04511.15 KRH93473.1 - 2.5e-36 125.4 18.9 3.1e-36 125.1 18.9 1.1 1 0 0 1 1 1 1 Der1-like family E1-E2_ATPase PF00122.20 KRH93474.1 - 2.8e-15 56.3 0.0 1.3e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KRH93474.1 - 4.6e-11 43.4 0.0 4.8e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRH93474.1 - 5.2e-08 32.9 0.1 1.5e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) P5-ATPase PF12409.8 KRH93474.1 - 7e-06 26.2 1.8 7e-06 26.2 1.8 3.6 3 1 0 3 3 3 1 P5-type ATPase cation transporter HD_3 PF13023.6 KRH93474.1 - 0.072 13.0 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 HD domain RVT_1 PF00078.27 KRH93475.1 - 5.1e-33 114.5 0.8 9.9e-33 113.5 0.8 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH93475.1 - 1.4e-29 102.4 0.0 3.9e-29 101.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93475.1 - 1.2e-27 95.9 0.0 2.9e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93475.1 - 2.7e-16 59.8 0.0 7.8e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93475.1 - 3.1e-12 46.4 1.0 8e-12 45.1 0.5 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 KRH93475.1 - 0.0093 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain LETM1 PF07766.13 KRH93475.1 - 0.0094 15.3 0.6 0.028 13.8 0.6 1.8 1 0 0 1 1 1 1 LETM1-like protein RVT_3 PF13456.6 KRH93475.1 - 0.032 14.1 0.1 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase-like eIF3g PF12353.8 KRH93476.1 - 0.00038 20.8 0.1 0.00061 20.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G EF-hand_7 PF13499.6 KRH93477.1 - 0.0022 18.4 1.1 0.011 16.2 1.1 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 KRH93477.1 - 0.0024 17.7 1.4 0.0063 16.3 0.2 2.3 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KRH93477.1 - 0.0075 15.8 4.5 0.04 13.5 0.0 3.8 3 1 1 4 4 4 1 EF hand EF-hand_6 PF13405.6 KRH93477.1 - 0.0076 16.1 3.5 6.8 6.9 0.0 4.1 3 1 2 5 5 5 2 EF-hand domain YhdB PF14148.6 KRH93477.1 - 0.11 12.6 0.7 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 YhdB-like protein zf-RING_5 PF14634.6 KRH93478.1 - 0.0051 16.7 12.2 0.016 15.1 12.2 1.9 1 1 0 1 1 1 1 zinc-RING finger domain DUF2746 PF10874.8 KRH93478.1 - 0.011 16.1 0.1 0.04 14.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) DUF5595 PF18077.1 KRH93478.1 - 0.016 15.3 0.5 0.031 14.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Prok-RING_4 PF14447.6 KRH93478.1 - 0.17 11.8 8.3 0.34 10.8 8.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 XkdW PF09636.10 KRH93478.1 - 0.21 11.7 0.9 0.38 10.9 0.3 1.8 2 0 0 2 2 2 0 XkdW protein zf-RING_2 PF13639.6 KRH93478.1 - 3 8.3 10.1 6.4 7.2 10.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KRH93478.1 - 9.1 6.2 11.5 48 3.9 11.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1517 PF07466.11 KRH93480.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) UDPGP PF01704.18 KRH93481.1 - 2.6e-07 29.6 0.0 3.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CDP-OH_P_transf PF01066.21 KRH93482.1 - 3.6e-09 37.3 2.4 3.6e-09 37.3 2.4 2.6 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase RR_TM4-6 PF06459.12 KRH93482.1 - 0.023 14.5 4.4 0.034 14.0 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2981 PF11200.8 KRH93482.1 - 0.034 13.9 0.2 0.047 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Mem_trans PF03547.18 KRH93482.1 - 0.24 9.8 5.2 0.21 10.0 4.0 1.4 1 1 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.16 KRH93482.1 - 0.42 10.6 2.8 0.69 9.9 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KRH93482.1 - 2.1 7.0 10.3 4.2 6.0 10.3 1.5 1 0 0 1 1 1 0 Presenilin UQ_con PF00179.26 KRH93483.1 - 6.1e-38 129.6 0.0 6.9e-38 129.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Lipase_GDSL_2 PF13472.6 KRH93483.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family YkyA PF10368.9 KRH93484.1 - 3e-05 23.8 4.9 3.6e-05 23.5 4.9 1.2 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Spc7 PF08317.11 KRH93484.1 - 0.0011 18.0 1.7 0.0012 17.7 1.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KRH93484.1 - 0.0034 17.4 7.0 0.0051 16.9 7.0 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 KRH93484.1 - 0.0046 17.3 0.1 0.0063 16.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) TelA PF05816.11 KRH93484.1 - 0.0083 15.2 1.0 0.01 14.9 1.0 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) GrpE PF01025.19 KRH93484.1 - 0.0088 15.7 3.6 0.012 15.2 3.6 1.2 1 0 0 1 1 1 1 GrpE DivIC PF04977.15 KRH93484.1 - 0.013 15.2 2.9 0.022 14.5 2.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3450 PF11932.8 KRH93484.1 - 0.021 14.1 1.4 0.028 13.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 KRH93484.1 - 0.061 12.6 3.2 0.068 12.4 3.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4041 PF13250.6 KRH93484.1 - 0.063 13.2 0.4 2.3 8.2 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4041) DUF1664 PF07889.12 KRH93484.1 - 0.083 12.9 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KRH93484.1 - 0.18 11.1 0.6 0.18 11.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4695 PF15766.5 KRH93484.1 - 0.19 12.0 4.4 0.31 11.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Prefoldin_2 PF01920.20 KRH93484.1 - 0.21 11.6 10.0 0.4 10.7 10.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF4337 PF14235.6 KRH93484.1 - 0.24 11.5 1.6 0.31 11.1 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3552 PF12072.8 KRH93484.1 - 0.31 10.4 9.7 0.039 13.4 5.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) LMBR1 PF04791.16 KRH93484.1 - 0.69 8.8 3.3 0.77 8.6 3.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2951 PF11166.8 KRH93484.1 - 1.2 9.4 6.8 2.1 8.6 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF3958 PF13125.6 KRH93484.1 - 1.6 9.0 9.2 2.7 8.2 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Prefoldin PF02996.17 KRH93484.1 - 1.6 8.7 8.3 7.4 6.5 8.3 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF1043 PF06295.12 KRH93484.1 - 2.2 8.3 7.3 7.7 6.5 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) BAR PF03114.18 KRH93484.1 - 2.6 7.6 10.6 3.8 7.1 10.6 1.2 1 0 0 1 1 1 0 BAR domain Fusion_gly PF00523.18 KRH93484.1 - 2.9 6.0 4.6 7.1 4.8 4.0 1.6 1 1 1 2 2 2 0 Fusion glycoprotein F0 Bromodomain PF00439.25 KRH93485.1 - 3.7e-20 71.8 1.3 6.5e-20 71.0 1.3 1.3 1 0 0 1 1 1 1 Bromodomain DHHC PF01529.20 KRH93488.1 - 1e-14 54.8 14.8 1e-14 54.8 14.8 2.7 3 0 0 3 3 3 2 DHHC palmitoyltransferase RFC1 PF08519.12 KRH93489.1 - 1.6e-20 73.9 0.4 3.2e-20 72.9 0.4 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KRH93489.1 - 8.4e-12 45.3 1.3 7.8e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KRH93489.1 - 1.7e-11 44.7 0.0 3.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KRH93489.1 - 8.5e-06 25.8 0.5 4.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KRH93489.1 - 3.1e-05 24.4 0.0 8.9e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KRH93489.1 - 8.2e-05 23.0 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KRH93489.1 - 0.00028 21.2 0.1 0.0017 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KRH93489.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRH93489.1 - 0.0014 18.6 0.2 0.0055 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KRH93489.1 - 0.0075 15.5 0.1 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KRH93489.1 - 0.0092 15.7 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KRH93489.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KRH93489.1 - 0.021 14.8 0.1 0.31 10.9 0.0 2.3 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.14 KRH93489.1 - 0.024 14.6 0.0 0.09 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KRH93489.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KRH93489.1 - 0.035 13.5 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 KRH93489.1 - 0.04 13.7 0.1 0.53 10.0 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KRH93489.1 - 0.06 13.1 0.0 0.31 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2529 PF10740.9 KRH93489.1 - 0.08 12.6 0.1 0.86 9.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2529) TniB PF05621.11 KRH93489.1 - 0.096 12.1 0.1 17 4.7 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 KRH93490.1 - 1.2e-10 41.1 2.8 1.2e-10 41.1 2.8 2.5 1 1 2 3 3 3 2 TIP49 P-loop domain B3 PF02362.21 KRH93490.1 - 0.0007 19.4 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 B3 DNA binding domain Branch PF02485.21 KRH93490.1 - 0.0054 16.3 0.4 0.38 10.2 0.2 2.3 2 0 0 2 2 2 2 Core-2/I-Branching enzyme Asp_decarbox PF02261.16 KRH93490.1 - 0.0087 16.0 0.1 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Aspartate decarboxylase CzcE PF16986.5 KRH93490.1 - 0.1 13.0 0.1 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal resistance protein CzcE MS_channel PF00924.18 KRH93492.1 - 5.1e-13 49.1 2.2 9.1e-13 48.2 2.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Membr_traf_MHD PF10540.9 KRH93492.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain HTH_Tnp_1_2 PF13022.6 KRH93492.1 - 0.13 12.4 1.3 0.4 10.8 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase PCI PF01399.27 KRH93494.1 - 4.9e-13 49.5 2.9 9e-13 48.6 1.3 2.2 2 0 0 2 2 2 1 PCI domain Spo0A_C PF08769.11 KRH93495.1 - 0.041 14.0 0.3 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 Sporulation initiation factor Spo0A C terminal RVT_1 PF00078.27 KRH93496.1 - 9.8e-05 22.0 0.5 0.0001 21.9 0.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CheR PF01739.18 KRH93496.1 - 0.051 13.1 0.4 0.068 12.6 0.4 1.3 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Phage_CP76 PF06892.11 KRH93497.1 - 0.0052 16.3 0.0 0.0064 16.0 0.0 1.2 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) VATC PF18716.1 KRH93500.1 - 0.043 13.7 1.2 9.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain SET PF00856.28 KRH93501.1 - 3e-20 73.3 2.6 9.8e-20 71.6 0.2 2.9 2 1 0 2 2 2 1 SET domain Flu_C_NS1 PF03506.13 KRH93501.1 - 3.2 7.7 7.4 15 5.5 7.4 2.1 1 1 0 1 1 1 0 Influenza C non-structural protein (NS1) DUF5348 PF17295.2 KRH93502.1 - 0.047 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) TMIE PF16038.5 KRH93502.1 - 0.75 9.7 8.2 2.1 8.3 2.8 3.1 2 0 0 2 2 2 0 TMIE protein Presenilin PF01080.17 KRH93502.1 - 0.84 8.3 17.8 1.3 7.7 17.8 1.3 1 0 0 1 1 1 0 Presenilin DDE_3 PF13358.6 KRH93503.1 - 3e-05 23.8 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_1 PF01359.18 KRH93503.1 - 0.18 11.7 0.0 0.88 9.4 0.0 1.9 2 0 0 2 2 2 0 Transposase (partial DDE domain) tRNA-synt_2 PF00152.20 KRH93505.1 - 3.2e-24 85.6 0.1 4.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KRH93505.1 - 5.1e-12 45.6 0.7 8.7e-12 44.9 0.7 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mnd1 PF03962.15 KRH93506.1 - 1.2e-18 67.1 1.2 3.1e-18 65.8 0.0 2.2 2 1 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 KRH93506.1 - 1.2e-11 44.5 1.2 2.2e-11 43.6 0.2 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DUF2353 PF09789.9 KRH93506.1 - 0.00044 19.7 7.8 0.00067 19.1 7.8 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) HAP2-GCS1 PF10699.9 KRH93506.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Male gamete fusion factor E2F_CC-MB PF16421.5 KRH93506.1 - 0.043 14.2 2.5 0.089 13.2 2.5 1.7 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain DivIC PF04977.15 KRH93506.1 - 0.23 11.2 7.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator LMBR1 PF04791.16 KRH93506.1 - 0.26 10.2 1.3 0.27 10.1 1.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EamA PF00892.20 KRH93507.1 - 0.00017 21.7 13.5 0.00017 21.7 13.5 3.2 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.11 KRH93507.1 - 0.00079 18.7 31.3 0.0012 18.1 31.3 1.3 1 0 0 1 1 1 1 UAA transporter family Clathrin_propel PF01394.20 KRH93507.1 - 0.078 13.3 1.0 0.74 10.2 0.2 2.7 2 0 0 2 2 2 0 Clathrin propeller repeat RT_RNaseH PF17917.1 KRH93508.1 - 1.9e-34 118.1 0.1 6.2e-34 116.4 0.1 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93508.1 - 1.2e-30 105.5 2.3 1.8e-30 104.9 0.1 2.5 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93508.1 - 2.8e-28 99.0 0.1 1.1e-27 97.1 0.1 2.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH93508.1 - 1.8e-19 70.1 0.1 8.9e-19 67.8 0.0 2.3 3 0 0 3 3 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93508.1 - 3.9e-11 42.9 0.0 1.4e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 KRH93508.1 - 7.2e-09 35.9 0.1 2.2e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease MLVIN_C PF18697.1 KRH93508.1 - 0.0011 19.0 0.1 0.0047 17.0 0.1 2.1 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_Tnp_IS240 PF13610.6 KRH93508.1 - 0.0053 17.0 0.2 0.03 14.5 0.0 2.4 2 0 0 2 2 2 1 DDE domain gag-asp_proteas PF13975.6 KRH93508.1 - 0.014 15.9 0.1 0.045 14.3 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KRH93508.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 KRH93508.1 - 0.078 13.6 0.1 0.32 11.6 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease DUF3884 PF13024.6 KRH93510.1 - 0.063 12.8 0.9 1.4 8.6 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3884) Asp_protease_2 PF13650.6 KRH93511.1 - 3.2e-06 27.7 0.0 6.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH93511.1 - 3.7e-06 27.4 0.0 8.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KRH93511.1 - 0.0087 16.3 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KRH93511.1 - 0.017 14.9 0.1 0.041 13.7 0.1 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 KRH93511.1 - 0.024 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.6 KRH93512.1 - 4.6e-06 26.3 0.1 2.6e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 KRH93512.1 - 0.0035 17.5 0.1 0.0067 16.6 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain YbjQ_1 PF01906.17 KRH93512.1 - 0.15 12.8 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative heavy-metal-binding ANAPC4_WD40 PF12894.7 KRH93513.1 - 0.065 13.5 0.1 1.7 9.0 0.0 3.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain SAS-6_N PF16531.5 KRH93514.1 - 6.4e-13 49.1 8.8 6.4e-13 49.1 8.8 3.0 2 1 0 2 2 2 1 Centriolar protein SAS N-terminal FliD_N PF02465.18 KRH93514.1 - 0.00088 19.9 2.4 0.00088 19.9 2.4 3.4 2 1 1 3 3 3 1 Flagellar hook-associated protein 2 N-terminus DUF4175 PF13779.6 KRH93514.1 - 3 5.6 11.7 4.3 5.1 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ACI44 PF15270.6 KRH93515.1 - 0.057 13.6 1.2 0.057 13.6 1.2 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor PH_11 PF15413.6 KRH93516.1 - 0.031 14.7 0.2 0.031 14.7 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain rve PF00665.26 KRH93518.1 - 0.063 13.5 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain DUF5645 PF18713.1 KRH93521.1 - 0.076 13.3 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) NOG1_N PF17835.1 KRH93523.1 - 6.6e-38 130.2 0.9 6.6e-38 130.2 0.9 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KRH93523.1 - 9.9e-21 73.3 0.1 3.3e-20 71.6 0.1 2.0 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KRH93523.1 - 1.4e-15 57.3 0.0 4e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 KRH93523.1 - 1.2e-09 38.1 6.2 1.2e-09 38.1 6.2 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.18 KRH93523.1 - 3.1e-08 33.3 0.3 1.6e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Lip_prot_lig_C PF10437.9 KRH93523.1 - 0.006 16.5 0.6 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus PPV_E1_C PF00519.17 KRH93523.1 - 0.03 13.2 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase RsgA_GTPase PF03193.16 KRH93523.1 - 0.053 13.4 0.2 1.1 9.1 0.0 3.2 3 1 0 3 3 3 0 RsgA GTPase DUF3173 PF11372.8 KRH93523.1 - 0.1 12.5 0.5 2.3 8.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3173) Dynamin_N PF00350.23 KRH93523.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.6 2 2 1 3 3 3 0 Dynamin family Histone PF00125.24 KRH93524.1 - 0.0017 18.8 1.2 0.0018 18.6 1.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RE_HaeIII PF09556.10 KRH93524.1 - 0.088 11.9 0.0 0.095 11.8 0.0 1.0 1 0 0 1 1 1 0 HaeIII restriction endonuclease Ribosomal_L1 PF00687.21 KRH93529.1 - 2.2e-16 60.2 3.1 2.7e-16 59.9 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF771 PF05595.11 KRH93529.1 - 0.13 12.2 3.5 0.21 11.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF771) Imm26 PF15428.6 KRH93534.1 - 0.037 14.3 0.2 0.051 13.8 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 26 AAA PF00004.29 KRH93535.1 - 9.4e-98 323.8 0.2 9e-49 165.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH93535.1 - 6.3e-25 86.7 1.8 7.2e-12 44.9 0.0 3.4 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 KRH93535.1 - 7.2e-15 55.1 0.0 1.3e-06 28.2 0.0 3.5 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KRH93535.1 - 3e-14 53.5 0.0 1.9e-05 24.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KRH93535.1 - 3.7e-11 43.5 0.9 0.0068 16.7 0.2 4.5 2 2 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KRH93535.1 - 1.4e-10 41.8 0.5 0.00095 19.6 0.0 4.1 2 2 1 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 KRH93535.1 - 5.2e-10 39.5 1.6 0.00031 20.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain AAA_5 PF07728.14 KRH93535.1 - 9.8e-10 38.6 0.2 0.00042 20.3 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KRH93535.1 - 1.7e-09 37.9 0.0 0.0023 18.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KRH93535.1 - 2.2e-09 38.0 0.1 0.0034 17.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KRH93535.1 - 1.1e-08 35.0 0.3 0.013 15.3 0.0 3.9 3 1 1 4 4 4 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KRH93535.1 - 1.3e-08 35.1 0.0 0.002 18.5 0.0 3.7 3 0 0 3 3 3 2 RNA helicase ATPase PF06745.13 KRH93535.1 - 8.3e-08 31.9 0.3 0.45 9.8 0.0 3.8 3 0 0 3 3 3 3 KaiC Vps4_C PF09336.10 KRH93535.1 - 1.1e-07 31.7 1.0 9.5e-06 25.5 0.1 3.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KRH93535.1 - 1.3e-07 31.2 0.2 0.009 15.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KRH93535.1 - 2e-07 30.8 1.1 0.46 10.0 0.0 4.0 3 1 0 4 4 4 3 AAA domain TIP49 PF06068.13 KRH93535.1 - 3.6e-07 29.7 5.2 0.0022 17.3 0.0 3.1 4 0 0 4 4 2 2 TIP49 P-loop domain ABC_tran PF00005.27 KRH93535.1 - 4.1e-06 27.4 0.4 0.22 12.0 0.0 3.7 3 0 0 3 3 3 2 ABC transporter Parvo_NS1 PF01057.17 KRH93535.1 - 4.9e-06 25.8 0.1 0.032 13.3 0.1 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KRH93535.1 - 5.1e-06 26.8 0.0 0.092 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KRH93535.1 - 6.7e-06 26.2 0.0 2.3e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_7 PF12775.7 KRH93535.1 - 1.1e-05 25.1 0.0 0.21 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KRH93535.1 - 5.7e-05 22.9 0.0 0.76 9.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 KRH93535.1 - 9.6e-05 22.4 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KRH93535.1 - 0.00013 22.4 0.3 0.6 10.5 0.0 3.5 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KRH93535.1 - 0.00031 20.7 0.1 0.68 9.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 KRH93535.1 - 0.00033 20.5 0.0 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KRH93535.1 - 0.00041 19.9 0.2 0.85 9.0 0.1 2.8 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KRH93535.1 - 0.00055 19.8 0.0 0.48 10.3 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KRH93535.1 - 0.00066 19.4 0.0 0.81 9.4 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 KRH93535.1 - 0.00067 19.6 0.1 0.5 10.2 0.0 3.0 3 0 0 3 3 2 1 Bacterial dnaA protein NB-ARC PF00931.22 KRH93535.1 - 0.0012 18.1 0.0 0.95 8.6 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KRH93535.1 - 0.0015 18.7 0.0 1 9.4 0.0 3.3 3 0 0 3 3 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 KRH93535.1 - 0.0017 18.3 2.2 0.57 10.1 0.0 3.7 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KRH93535.1 - 0.0028 17.6 0.5 6.3 6.7 0.0 4.3 3 1 0 4 4 4 0 NTPase Rad17 PF03215.15 KRH93535.1 - 0.0045 16.9 5.1 0.3 11.0 0.0 3.6 4 2 0 4 4 3 1 Rad17 P-loop domain DUF2075 PF09848.9 KRH93535.1 - 0.0048 16.2 3.1 0.66 9.1 0.0 3.0 4 0 0 4 4 3 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KRH93535.1 - 0.0061 15.9 0.1 5.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.13 KRH93535.1 - 0.0077 15.4 0.0 0.73 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CDC48_2 PF02933.17 KRH93535.1 - 0.016 15.0 0.0 0.056 13.2 0.0 1.9 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), domain 2 PduV-EutP PF10662.9 KRH93535.1 - 0.026 14.3 0.0 9.8 5.9 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.16 KRH93535.1 - 0.087 12.2 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 KRH93535.1 - 0.096 12.4 0.2 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 KRH93535.1 - 0.1 12.2 0.0 1.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.25 KRH93535.1 - 0.1 12.2 0.0 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Hydin_ADK PF17213.3 KRH93535.1 - 0.13 12.6 1.7 8.5 6.6 0.0 3.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain AAA_19 PF13245.6 KRH93535.1 - 0.13 12.6 6.0 3.2 8.1 0.1 3.6 3 1 0 4 4 3 0 AAA domain AAA_11 PF13086.6 KRH93535.1 - 2.5 7.8 14.0 5 6.8 0.2 4.2 4 1 0 4 4 4 0 AAA domain DEAD PF00270.29 KRH93537.1 - 2e-23 83.1 1.6 3.7e-23 82.2 0.1 2.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH93537.1 - 1.4e-19 70.4 2.0 4.7e-17 62.3 0.2 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93537.1 - 1.3e-06 28.6 0.2 1.3e-06 28.6 0.2 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ELP6 PF09807.9 KRH93537.1 - 0.013 14.9 1.1 3.5 7.0 0.3 2.4 1 1 1 2 2 2 0 Elongation complex protein 6 Med26_C PF15693.5 KRH93537.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.7 3 0 0 3 3 3 0 Mediator complex subunit 26 C-terminal DEAD PF00270.29 KRH93538.1 - 7.1e-18 65.0 2.9 9.2e-18 64.6 0.1 2.6 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH93538.1 - 1.2e-12 48.2 0.2 4.4e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93538.1 - 4.6e-10 39.8 0.5 1.1e-08 35.3 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KRH93538.1 - 0.00038 20.7 0.1 0.0056 17.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 KRH93538.1 - 0.00084 18.8 0.0 0.0044 16.5 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein PhoH PF02562.16 KRH93538.1 - 0.0017 17.9 0.0 0.0064 16.0 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KRH93538.1 - 0.0062 16.3 0.0 0.04 13.7 0.0 2.4 3 1 0 3 3 3 1 IstB-like ATP binding protein T2SSE PF00437.20 KRH93538.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Peroxin-13_N PF04088.13 KRH93538.1 - 0.056 13.7 0.1 0.3 11.3 0.1 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AAA PF00004.29 KRH93538.1 - 0.085 13.3 0.5 2.1 8.8 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KRH93539.1 - 9.3e-25 87.7 0.1 1.7e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KRH93539.1 - 1.8e-07 30.8 0.8 5.8e-07 29.2 0.8 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KRH93539.1 - 7.6e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KRH93539.1 - 0.00012 22.7 2.2 0.00039 21.0 2.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH93539.1 - 0.00017 22.0 0.0 0.00059 20.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KRH93539.1 - 0.00017 21.5 0.1 0.00049 20.0 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KRH93539.1 - 0.0008 19.1 0.4 0.0018 17.9 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KRH93539.1 - 0.0014 18.5 3.3 0.25 11.1 0.4 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KRH93539.1 - 0.0024 17.0 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.23 KRH93539.1 - 0.003 17.6 0.1 0.0063 16.6 0.1 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KRH93539.1 - 0.0063 16.6 0.4 0.015 15.3 0.4 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 KRH93539.1 - 0.0089 16.2 0.0 0.17 12.2 0.0 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KRH93539.1 - 0.0092 15.9 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KRH93539.1 - 0.01 15.8 0.3 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 NTPase MobB PF03205.14 KRH93539.1 - 0.014 15.3 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 KRH93539.1 - 0.021 14.0 0.1 0.046 12.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KRH93539.1 - 0.026 15.1 0.1 0.07 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KRH93539.1 - 0.032 13.8 0.2 0.072 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KRH93539.1 - 0.043 13.4 0.5 0.081 12.5 0.5 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KRH93539.1 - 0.047 14.0 0.5 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KRH93539.1 - 0.048 14.0 0.3 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KRH93539.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRH93539.1 - 0.095 12.4 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KRH93539.1 - 0.1 13.0 0.2 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KRH93539.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KRH93539.1 - 0.14 12.3 0.3 0.27 11.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KRH93539.1 - 0.18 12.1 0.7 0.29 11.3 0.7 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KRH93539.1 - 0.18 12.2 1.6 1.5 9.2 1.6 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_P4 PF11602.8 KRH93539.1 - 0.23 10.6 0.1 0.37 10.0 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 LRR_adjacent PF08191.11 KRH93539.1 - 0.4 10.9 1.6 4.1 7.7 0.2 2.8 2 0 0 2 2 2 0 LRR adjacent ABC2_membrane_3 PF12698.7 KRH93539.1 - 0.69 9.0 31.9 2.6 7.1 31.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF87 PF01935.17 KRH93539.1 - 3.4 7.7 7.1 6.8 6.7 0.6 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 KRH93540.1 - 7.2e-29 101.3 0.1 1e-28 100.7 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KRH93540.1 - 0.0049 16.9 0.1 0.051 13.6 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KRH93540.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 KRH93540.1 - 0.038 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRH93540.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KRH93540.1 - 0.058 13.7 0.2 0.23 11.8 0.0 2.0 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 KRH93540.1 - 0.08 12.5 0.2 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KRH93540.1 - 0.11 12.9 0.1 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KRH93540.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KRH93540.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KRH93540.1 - 0.28 11.2 2.9 0.66 10.0 0.2 2.8 1 1 2 3 3 3 0 AAA domain RRM_1 PF00076.22 KRH93541.1 - 8.6e-08 31.9 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KRH93541.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Myb_DNA-bind_7 PF15963.5 KRH93542.1 - 2.8e-18 65.6 2.0 2.8e-18 65.6 2.0 2.7 1 1 0 2 2 2 1 Myb DNA-binding like Pentapeptide_4 PF13599.6 KRH93542.1 - 6.3e-11 42.3 1.8 2.7e-10 40.3 0.5 2.4 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) APC_u9 PF16633.5 KRH93542.1 - 0.85 10.8 0.1 0.85 10.8 0.1 2.4 2 1 1 3 3 3 0 Unstructured region on APC between 1st two creatine-rich regions DUF4905 PF16248.5 KRH93542.1 - 1.4 8.9 6.9 2.9 7.9 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4905) GCD14 PF08704.10 KRH93542.1 - 2.4 7.7 9.6 0.35 10.5 5.6 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Pyr_redox_2 PF07992.14 KRH93543.1 - 3.6e-35 121.6 0.1 2.7e-27 95.8 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KRH93543.1 - 2.4e-20 72.8 0.0 7.7e-20 71.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KRH93543.1 - 5.1e-14 52.6 2.1 3e-13 50.1 0.5 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KRH93543.1 - 0.00016 21.0 1.9 0.97 8.6 0.1 4.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRH93543.1 - 0.00021 20.5 0.0 0.00041 19.6 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KRH93543.1 - 0.00028 20.3 0.0 0.43 9.8 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KRH93543.1 - 0.017 13.8 0.1 0.47 9.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 KRH93543.1 - 0.11 12.8 0.1 9.4 6.5 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Zip PF02535.22 KRH93543.1 - 0.26 10.5 1.7 0.39 9.9 1.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 KRH93543.1 - 1.1 7.7 10.5 2 6.9 10.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF5314 PF17241.2 KRH93545.1 - 0.00029 20.6 0.1 0.00036 20.3 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5314) Na_H_Exchanger PF00999.21 KRH93546.1 - 7.2e-44 150.1 35.0 9.1e-44 149.8 35.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 KRH93548.1 - 4.1e-09 36.4 0.0 1.8e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Csm1_B PF18211.1 KRH93548.1 - 0.11 12.3 1.0 0.84 9.5 0.0 2.8 3 0 0 3 3 3 0 Csm1 subunit domain B Nup54 PF13874.6 KRH93549.1 - 4.4e-08 33.3 0.8 9.2e-08 32.3 0.8 1.7 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Bap31_Bap29_C PF18035.1 KRH93551.1 - 7.2 6.7 9.2 2.9 8.0 5.4 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MDFI PF15316.6 KRH93553.1 - 0.1 12.7 1.0 0.17 12.0 1.0 1.3 1 0 0 1 1 1 0 MyoD family inhibitor RP-C_C PF11800.8 KRH93553.1 - 3.8 7.6 5.1 9.3 6.3 5.2 1.5 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF5439 PF17507.2 KRH93556.1 - 7 6.9 9.6 19 5.6 1.6 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5439) XRN_N PF03159.18 KRH93558.1 - 3.6e-75 252.5 0.2 7e-75 251.6 0.2 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KRH93558.1 - 6e-46 157.3 10.9 2.1e-28 99.5 0.9 2.6 2 1 1 3 3 3 2 Xrn1 helical domain Zip PF02535.22 KRH93561.1 - 0.0011 18.2 19.1 0.015 14.5 17.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2985 PF11204.8 KRH93561.1 - 0.013 15.6 0.1 0.023 14.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2985) NicO PF03824.16 KRH93561.1 - 0.041 13.2 1.8 0.049 13.0 1.8 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein zf-LITAF-like PF10601.9 KRH93561.1 - 8.4 6.7 8.7 19 5.6 1.5 2.5 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain MAGP PF05507.11 KRH93562.1 - 0.0077 16.6 0.1 0.021 15.2 0.1 1.7 1 0 0 1 1 1 1 Microfibril-associated glycoprotein (MAGP) EF-hand_10 PF14788.6 KRH93564.1 - 0.0017 18.2 0.8 0.47 10.3 0.0 2.6 2 0 0 2 2 2 2 EF hand PTPS PF01242.19 KRH93564.1 - 0.027 14.4 0.6 0.04 13.9 0.6 1.3 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase MLVIN_C PF18697.1 KRH93565.1 - 4.6e-05 23.4 0.0 9.1e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Integrase_H2C2 PF17921.1 KRH93566.1 - 0.037 14.1 0.9 0.037 14.1 0.9 1.6 2 0 0 2 2 2 0 Integrase zinc binding domain RVT_1 PF00078.27 KRH93568.1 - 1e-10 41.5 0.4 1.2e-10 41.3 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.8 KRH93569.1 - 0.00032 20.3 0.7 0.00068 19.2 0.2 1.8 1 1 1 2 2 2 1 Ty3 transposon peptidase RVP_2 PF08284.11 KRH93569.1 - 0.00034 20.4 0.4 0.00097 18.9 0.4 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93569.1 - 0.00045 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH93569.1 - 0.0037 17.8 0.0 0.0094 16.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KRH93572.1 - 3.3e-10 40.2 0.1 4.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH93572.1 - 0.00085 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KRH93572.1 - 0.0011 19.4 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH93572.1 - 0.019 15.6 0.1 0.03 14.9 0.1 1.5 1 1 0 1 1 1 0 Aspartyl protease WD40_like PF17005.5 KRH93574.1 - 0.0035 16.7 0.4 0.0039 16.5 0.4 1.1 1 0 0 1 1 1 1 WD40-like domain TPR_2 PF07719.17 KRH93575.1 - 0.0026 17.8 1.9 5.1 7.5 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KRH93575.1 - 0.049 14.3 0.0 1.3 9.8 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KRH93575.1 - 0.064 13.5 1.9 5.7 7.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KRH93575.1 - 0.085 13.2 0.7 9 6.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat YqfQ PF14181.6 KRH93575.1 - 0.2 11.8 11.9 0.34 11.1 4.3 2.3 2 0 0 2 2 2 0 YqfQ-like protein TPR_1 PF00515.28 KRH93575.1 - 0.33 10.8 1.9 21 5.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cupin_8 PF13621.6 KRH93575.1 - 1.9 8.2 8.2 0.18 11.5 1.6 2.0 2 0 0 2 2 2 0 Cupin-like domain TFB6 PF17110.5 KRH93575.1 - 6.9 6.4 9.5 6.1 6.6 0.1 3.0 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TLC PF03219.14 KRH93577.1 - 6.5e-49 167.0 31.2 9.6e-49 166.4 31.2 1.2 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF1772 PF08592.11 KRH93577.1 - 0.8 10.0 14.6 0.093 13.0 1.7 3.7 1 1 0 3 3 3 0 Domain of unknown function (DUF1772) HTH_Tnp_Tc3_2 PF01498.18 KRH93578.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Transposase ABC_tran PF00005.27 KRH93579.1 - 2.3e-14 54.1 0.2 2.3e-14 54.1 0.2 3.4 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 KRH93579.1 - 3.1e-11 43.4 3.6 3.1e-11 43.4 3.6 2.2 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KRH93579.1 - 0.008 15.6 0.8 0.008 15.6 0.8 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KRH93579.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KRH93579.1 - 0.013 15.4 0.1 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KRH93579.1 - 0.066 13.3 0.1 0.066 13.3 0.1 3.8 4 1 0 4 4 4 0 Dynamin family MMR_HSR1 PF01926.23 KRH93579.1 - 0.067 13.3 0.8 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KRH93579.1 - 0.082 12.6 1.6 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KRH93579.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Acetyltransf_1 PF00583.25 KRH93580.1 - 2.5e-07 30.9 0.1 3.4e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KRH93580.1 - 1.1e-06 28.6 0.2 2.5e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KRH93580.1 - 3.6e-05 24.1 0.1 5.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BRX_N PF13713.6 KRH93580.1 - 0.047 13.5 1.8 5.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain VP4_2 PF08935.10 KRH93580.1 - 0.047 14.3 1.3 0.13 12.9 1.3 1.8 1 0 0 1 1 1 0 Viral protein VP4 subunit DUF2973 PF11189.8 KRH93580.1 - 0.19 11.8 1.2 1.1 9.4 1.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) DEAD PF00270.29 KRH93581.1 - 3.9e-45 153.8 0.0 1.1e-44 152.3 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH93581.1 - 2.7e-33 114.6 0.4 2.9e-32 111.3 0.2 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93581.1 - 0.0005 20.1 0.0 0.0016 18.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KRH93581.1 - 0.0015 17.8 0.7 0.0029 16.9 0.7 1.5 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KRH93581.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helicase_C_4 PF13871.6 KRH93581.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.5 1 1 0 1 1 1 0 C-terminal domain on Strawberry notch homologue DUF4227 PF14004.6 KRH93582.1 - 0.041 13.9 1.0 0.046 13.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Ribosomal_S13_N PF08069.12 KRH93583.1 - 2.4e-21 75.5 0.1 4e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KRH93583.1 - 8e-09 35.6 1.7 1.3e-08 34.9 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 KN17_SH3 PF18131.1 KRH93583.1 - 0.08 13.1 0.1 6.5 7.0 0.2 2.3 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain Pap_E4 PF02711.14 KRH93584.1 - 2.9 8.9 7.2 0.8 10.7 3.7 1.9 1 1 1 2 2 2 0 E4 protein dsDNA_bind PF01984.20 KRH93585.1 - 1.8e-15 57.1 0.0 2.1e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain zf-CHY PF05495.12 KRH93586.1 - 1.2e-14 54.5 34.2 1.2e-14 54.5 34.2 3.9 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 KRH93586.1 - 1.8e-08 34.2 8.4 1.8e-08 34.2 8.4 4.2 4 1 0 4 4 4 1 Zinc-ribbon zf-RING_2 PF13639.6 KRH93586.1 - 3.1e-08 33.8 5.4 3.1e-08 33.8 5.4 5.1 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KRH93586.1 - 2.4e-07 30.6 1.1 2.4e-07 30.6 1.1 4.5 4 3 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 KRH93586.1 - 6.9e-07 29.1 6.2 6.9e-07 29.1 6.2 5.9 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KRH93586.1 - 3.6e-06 26.7 6.1 3.6e-06 26.7 6.1 4.8 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH93586.1 - 0.00018 21.3 7.1 0.00018 21.3 7.1 5.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KRH93586.1 - 0.0018 18.5 4.4 0.0018 18.5 4.4 5.4 3 2 3 6 6 6 1 RING-H2 zinc finger domain Lipase_chap PF03280.14 KRH93586.1 - 0.03 14.3 1.7 0.045 13.7 1.7 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein TSC22 PF01166.18 KRH93586.1 - 0.27 11.6 9.5 0.36 11.2 0.2 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family MAGE PF01454.19 KRH93587.1 - 0.00033 20.4 3.6 0.0013 18.5 3.6 1.9 1 1 0 1 1 1 1 MAGE family TMF_DNA_bd PF12329.8 KRH93588.1 - 9.3e-05 22.3 12.9 9.3e-05 22.3 12.9 10.4 9 3 4 13 13 13 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 KRH93588.1 - 0.0015 19.0 4.2 0.0015 19.0 4.2 7.0 5 1 0 6 6 6 3 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KRH93588.1 - 7.9 6.8 24.5 0.2 12.0 3.6 5.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) EF-hand_1 PF00036.32 KRH93589.1 - 1e-05 24.7 2.0 0.34 10.5 0.1 4.0 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 KRH93589.1 - 9.1e-05 22.1 8.4 0.044 13.7 0.1 4.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KRH93589.1 - 0.00072 19.4 3.4 0.014 15.2 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair Serum_albumin PF00273.20 KRH93589.1 - 0.026 14.3 0.4 0.04 13.7 0.4 1.3 1 0 0 1 1 1 0 Serum albumin family EF-hand_7 PF13499.6 KRH93589.1 - 0.029 14.8 4.1 0.73 10.3 4.0 3.1 1 1 0 1 1 1 0 EF-hand domain pair Sen15 PF09631.10 KRH93589.1 - 0.12 12.7 0.5 0.59 10.5 0.1 2.1 1 1 2 3 3 3 0 Sen15 protein GSHPx PF00255.19 KRH93590.1 - 5.4e-20 71.0 2.0 1.7e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 Glutathione peroxidase INT_SG_DDX_CT_C PF15300.6 KRH93590.1 - 0.1 12.4 0.1 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sel1 PF08238.12 KRH93593.1 - 1.9e-21 76.0 24.6 1.1e-05 25.9 1.9 7.1 7 0 0 7 7 7 6 Sel1 repeat Fcf1 PF04900.12 KRH93594.1 - 8.5e-29 99.9 0.4 1.4e-28 99.2 0.4 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KRH93594.1 - 2.1e-15 57.1 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 PIN like domain GCV_T PF01571.21 KRH93594.1 - 0.0094 15.3 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Glycolytic PF00274.19 KRH93595.1 - 1.6e-92 310.0 0.0 1.2e-91 307.1 0.0 1.9 1 1 0 1 1 1 1 Fructose-bisphosphate aldolase class-I TraI_2_C PF07515.11 KRH93595.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Mltc_N PF11873.8 KRH93597.1 - 0.039 13.7 0.6 0.055 13.2 0.1 1.7 2 0 0 2 2 2 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Rad52_Rad22 PF04098.15 KRH93598.1 - 1.3e-50 171.3 1.0 1.6e-50 171.0 1.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ribonuc_L-PSP PF01042.21 KRH93598.1 - 0.042 13.9 0.1 0.067 13.2 0.1 1.4 1 1 0 1 1 1 0 Endoribonuclease L-PSP AAA_9 PF12781.7 KRH93598.1 - 0.045 12.9 0.2 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region Cnn_1N PF07989.11 KRH93600.1 - 0.0013 18.9 17.6 0.0013 18.9 17.6 8.6 3 3 5 8 8 8 1 Centrosomin N-terminal motif 1 ZapB PF06005.12 KRH93600.1 - 0.012 16.1 2.4 0.012 16.1 2.4 9.7 2 2 7 9 9 9 0 Cell division protein ZapB APG6_N PF17675.1 KRH93600.1 - 1.2 9.6 106.6 6.1 7.4 20.6 6.2 1 1 3 5 5 5 0 Apg6 coiled-coil region Pkinase PF00069.25 KRH93601.1 - 1.9e-08 34.0 0.4 1.9e-08 34.0 0.4 2.3 1 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 KRH93601.1 - 9.4e-08 32.3 0.1 4.2e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KRH93601.1 - 3.4e-07 30.0 7.1 0.0001 22.0 0.1 2.3 1 1 1 2 2 2 2 RIO1 family Kdo PF06293.14 KRH93601.1 - 3e-05 23.5 0.1 0.0055 16.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KRH93601.1 - 0.00012 21.0 5.8 0.00019 20.4 5.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KRH93601.1 - 0.0048 16.2 1.6 0.0076 15.6 0.9 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF572 PF04502.13 KRH93601.1 - 0.36 10.4 17.4 0.47 10.0 17.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Metallophos PF00149.28 KRH93604.1 - 4.9e-28 99.0 0.3 7.7e-28 98.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KRH93604.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PAN_3 PF08277.12 KRH93604.1 - 0.015 15.1 1.1 0.05 13.4 0.5 2.1 2 0 0 2 2 2 0 PAN-like domain DUF356 PF04009.12 KRH93604.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF356) zf-RRN7 PF11781.8 KRH93604.1 - 0.11 12.2 2.0 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GSIII_N PF12437.8 KRH93606.1 - 8.5e-52 175.0 0.0 1.7e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 KRH93606.1 - 4.5e-29 100.7 2.1 1.2e-28 99.3 2.1 1.8 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 KRH93606.1 - 8.8e-26 90.7 0.1 2.4e-25 89.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Peptidase_M16_C PF05193.21 KRH93607.1 - 0.00055 20.0 0.4 0.11 12.5 0.0 3.2 2 1 1 3 3 3 2 Peptidase M16 inactive domain V-ATPase_H_C PF11698.8 KRH93607.1 - 0.2 11.8 9.0 0.29 11.3 2.7 3.6 3 0 0 3 3 3 0 V-ATPase subunit H DNA_ligase_A_M PF01068.21 KRH93611.1 - 5.3e-42 143.8 2.9 1.9e-40 138.7 2.9 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KRH93611.1 - 2.2e-33 116.0 2.9 2.2e-33 116.0 2.9 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KRH93611.1 - 4.1e-25 88.3 0.0 1.3e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KRH93611.1 - 4.7e-07 30.3 0.5 8.9e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KRH93611.1 - 0.0023 17.8 1.0 0.025 14.4 0.8 2.8 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain Gtr1_RagA PF04670.12 KRH93611.1 - 0.0046 16.3 1.8 0.013 14.9 1.8 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIMP PF00965.17 KRH93611.1 - 0.023 14.5 0.5 0.096 12.5 0.1 2.1 2 0 0 2 2 2 0 Tissue inhibitor of metalloproteinase DUF3316 PF11777.8 KRH93611.1 - 0.085 12.9 0.1 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) GTP_EFTU PF00009.27 KRH93612.1 - 9.8e-41 139.4 0.0 1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KRH93612.1 - 7.5e-22 77.8 0.0 1.8e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KRH93612.1 - 1.3e-07 31.9 0.1 5.5e-07 29.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 KRH93612.1 - 0.0018 17.7 2.1 0.0099 15.3 0.9 2.4 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRH93612.1 - 0.0021 18.1 0.1 0.011 15.8 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KRH93612.1 - 0.21 11.3 0.2 0.84 9.4 0.2 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein M20_dimer PF07687.14 KRH93615.1 - 0.083 12.8 0.0 0.088 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_C48 PF02902.19 KRH93617.1 - 1.9e-11 44.2 0.4 2.7e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KRH93617.1 - 8.7e-06 24.7 3.6 4.7e-05 22.3 0.3 2.0 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase LupA PF18242.1 KRH93617.1 - 0.00085 19.0 0.1 0.0018 18.0 0.1 1.5 1 1 0 1 1 1 1 Legionella ubiquitin-specific protease A domain CD34_antigen PF06365.12 KRH93620.1 - 0.079 12.5 1.7 0.1 12.1 0.5 1.7 1 1 0 2 2 2 0 CD34/Podocalyxin family zf-Di19 PF05605.12 KRH93621.1 - 0.09 13.1 1.2 0.18 12.1 1.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KRH93621.1 - 0.16 12.9 1.4 0.45 11.5 1.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KRH93621.1 - 0.2 12.2 1.5 0.5 10.9 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Nuf2 PF03800.14 KRH93623.1 - 3.5e-14 53.1 1.4 3.5e-14 53.1 1.4 4.0 2 2 0 3 3 3 1 Nuf2 family TPR_12 PF13424.6 KRH93624.1 - 1.5e-09 38.0 0.2 1.6e-08 34.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KRH93624.1 - 1.6e-07 30.9 5.9 0.0011 18.9 0.4 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KRH93624.1 - 2e-06 27.4 3.9 3.5e-05 23.4 0.6 3.4 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 KRH93624.1 - 0.00056 19.9 13.5 0.0052 16.9 1.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat BRCA2 PF00634.18 KRH93624.1 - 0.0013 18.4 3.9 3.6 7.3 0.0 4.6 4 0 0 4 4 4 2 BRCA2 repeat TPR_1 PF00515.28 KRH93624.1 - 0.0016 18.2 0.8 0.0016 18.2 0.8 5.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KRH93624.1 - 0.0047 17.2 2.4 0.016 15.5 0.0 3.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KRH93624.1 - 0.0079 16.0 0.1 4.1 7.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KRH93624.1 - 0.019 15.1 2.6 0.054 13.6 1.1 2.4 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.18 KRH93624.1 - 0.038 14.0 2.5 0.087 12.9 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 KRH93624.1 - 0.076 12.5 2.7 0.079 12.4 0.4 2.2 2 0 0 2 2 2 0 SHNi-TPR TPR_7 PF13176.6 KRH93624.1 - 0.11 12.6 0.6 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 KRH93625.1 - 1.6e-106 356.9 15.3 1.9e-106 356.6 15.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_1 PF00078.27 KRH93630.1 - 9.9e-08 31.8 0.1 1.3e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) vATP-synt_AC39 PF01992.16 KRH93632.1 - 4.2e-32 112.0 13.6 6.3e-32 111.4 13.6 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Staph_opine_DH PF10100.9 KRH93632.1 - 0.0011 17.8 0.1 0.0018 17.0 0.1 1.3 1 0 0 1 1 1 1 Staphylopine dehydrogenase DUF2605 PF10792.9 KRH93632.1 - 0.068 13.1 0.8 10 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Mnd1 PF03962.15 KRH93633.1 - 0.071 13.4 0.5 0.3 11.4 0.1 2.3 2 0 0 2 2 2 0 Mnd1 HTH domain SNF2_N PF00176.23 KRH93634.1 - 7.5e-51 172.9 5.5 7.5e-51 172.9 5.5 3.1 1 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KRH93634.1 - 1.2e-18 67.5 3.7 1.6e-18 67.1 0.1 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93634.1 - 3.1e-11 43.6 0.3 3.1e-11 43.6 0.3 4.9 3 3 1 5 5 5 1 Type III restriction enzyme, res subunit DBINO PF13892.6 KRH93634.1 - 1.3e-09 38.5 18.1 1.3e-09 38.5 18.1 5.3 5 2 1 6 6 6 1 DNA-binding domain Ribosomal_L18 PF17135.4 KRH93636.1 - 1.1e-37 129.3 0.4 1.2e-37 129.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KRH93636.1 - 9.3e-06 26.3 0.5 1.3e-05 25.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF2420 PF10336.9 KRH93638.1 - 0.011 15.8 8.4 0.014 15.4 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2420) Mis14 PF08641.12 KRH93640.1 - 0.0091 16.3 0.2 0.0091 16.3 0.2 2.5 1 1 1 2 2 2 1 Kinetochore protein Mis14 like DUF4695 PF15766.5 KRH93640.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) AF0941-like PF14591.6 KRH93640.1 - 0.1 13.2 8.7 0.072 13.7 6.2 2.0 1 1 1 2 2 2 0 AF0941-like HAD_2 PF13419.6 KRH93641.1 - 5.6e-08 33.1 1.5 5.1e-07 30.0 1.5 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KRH93641.1 - 0.0094 15.8 0.2 0.18 11.7 0.2 2.6 1 1 0 1 1 1 1 Acid Phosphatase G3P_antiterm PF04309.12 KRH93641.1 - 0.029 13.8 0.1 1.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Hydrolase PF00702.26 KRH93641.1 - 0.1 12.8 0.0 1 9.6 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DnaJ_C PF01556.18 KRH93642.1 - 1.1e-22 80.7 0.1 1.8e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KRH93642.1 - 1.4e-16 60.3 2.8 5.3e-15 55.3 2.8 2.3 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KRH93642.1 - 1.4e-10 41.3 16.9 2.5e-10 40.6 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain LMSTEN PF07988.12 KRH93642.1 - 0.02 14.4 1.6 0.04 13.4 1.6 1.4 1 0 0 1 1 1 0 LMSTEN motif zf-RING_10 PF16685.5 KRH93642.1 - 0.075 13.2 5.4 0.45 10.7 0.4 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 Anti-TRAP PF15777.5 KRH93642.1 - 0.34 10.9 12.2 0.39 10.7 2.3 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HNH_5 PF14279.6 KRH93642.1 - 1.5 8.8 6.8 4.5 7.2 0.4 3.5 1 1 2 3 3 3 0 HNH endonuclease FYVE_2 PF02318.16 KRH93642.1 - 8.6 6.6 10.0 1e+02 3.1 4.7 3.1 2 1 0 2 2 2 0 FYVE-type zinc finger Cpn60_TCP1 PF00118.24 KRH93643.1 - 2e-116 389.6 15.0 2.4e-116 389.3 15.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tipalpha PF16753.5 KRH93643.1 - 0.0055 16.5 1.0 0.015 15.1 1.0 1.7 1 0 0 1 1 1 1 TNF-alpha-Inducing protein of Helicobacter EF-hand_7 PF13499.6 KRH93644.1 - 3.5e-05 24.2 3.9 0.00011 22.6 0.8 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KRH93644.1 - 5.5e-05 22.8 2.4 0.00012 21.7 1.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KRH93644.1 - 0.00011 21.5 2.4 0.00021 20.6 0.9 2.3 2 0 0 2 2 2 1 EF hand Dockerin_1 PF00404.18 KRH93644.1 - 0.017 15.3 0.3 0.032 14.4 0.3 1.5 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 KRH93644.1 - 0.022 14.3 0.5 0.022 14.3 0.5 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 KRH93644.1 - 0.026 14.4 0.6 0.13 12.1 0.3 2.3 1 1 1 2 2 2 0 EF-hand domain pair FliW PF02623.15 KRH93644.1 - 0.05 13.5 0.9 0.057 13.3 0.2 1.6 2 0 0 2 2 2 0 FliW protein TFIID_20kDa PF03847.13 KRH93645.1 - 1.2e-09 38.5 0.7 2e-09 37.8 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KRH93645.1 - 1.4e-06 28.4 0.0 1.7e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KRH93645.1 - 0.00031 21.1 0.1 0.00043 20.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KRH93645.1 - 0.00038 20.4 0.1 0.00068 19.6 0.1 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KRH93645.1 - 0.0021 18.1 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KRH93645.1 - 0.0085 16.4 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KRH93645.1 - 0.044 13.9 0.6 0.062 13.4 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) KH_8 PF17903.1 KRH93647.1 - 5.7e-22 77.6 1.8 1.5e-21 76.3 1.8 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KRH93647.1 - 0.16 11.8 0.3 0.16 11.8 0.3 2.3 2 0 0 2 2 2 0 KH domain Septin PF00735.18 KRH93648.1 - 2e-44 152.0 5.3 3.7e-44 151.1 5.3 1.4 1 0 0 1 1 1 1 Septin Homeodomain PF00046.29 KRH93649.1 - 2e-12 46.7 2.4 5e-12 45.5 2.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH93649.1 - 9.9e-05 22.2 0.1 0.00035 20.4 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HOCHOB PF17943.1 KRH93649.1 - 0.013 16.3 0.7 0.15 12.8 0.0 2.7 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox FH2 PF02181.23 KRH93650.1 - 8.1e-22 77.8 15.2 8.1e-22 77.8 15.2 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Bromodomain PF00439.25 KRH93651.1 - 2.9e-25 88.2 1.6 8.5e-25 86.7 1.6 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KRH93651.1 - 1.2e-06 28.8 0.1 2.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRH93651.1 - 6.9e-05 23.2 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRH93651.1 - 0.0017 18.3 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 KRH93651.1 - 0.24 10.8 0.0 0.24 10.8 0.0 2.5 2 1 1 3 3 3 0 GNAT acetyltransferase 2 DctP PF03480.13 KRH93652.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 RT_RNaseH PF17917.1 KRH93653.1 - 7.4e-27 93.7 0.0 8.1e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93653.1 - 3.9e-24 84.6 0.0 4.8e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Utp13 PF08625.11 KRH93653.1 - 0.021 14.8 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain DUF4428 PF14471.6 KRH93654.1 - 0.0075 16.2 0.1 0.008 16.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Trehalase PF01204.18 KRH93655.1 - 1.2e-102 344.4 1.5 1.2e-102 344.4 1.5 1.8 1 1 1 2 2 2 1 Trehalase Glyco_hydro_63 PF03200.16 KRH93655.1 - 0.00065 18.6 0.1 0.0022 16.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain DUF1797 PF08796.10 KRH93655.1 - 0.0041 17.2 0.4 0.054 13.6 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1797) zf-U11-48K PF05253.12 KRH93655.1 - 0.11 12.4 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger GDE_C PF06202.14 KRH93655.1 - 0.19 10.6 4.0 1.6 7.6 4.2 2.2 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DDE_Tnp_IS1595 PF12762.7 KRH93656.1 - 9.3e-21 74.4 0.2 1.1e-20 74.2 0.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH93656.1 - 7.2e-05 22.4 0.1 8.9e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Transposase IS66 family HemX PF04375.14 KRH93660.1 - 0.001 18.4 0.6 0.0011 18.3 0.6 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Neur_chan_memb PF02932.16 KRH93660.1 - 0.0092 16.1 0.1 0.012 15.7 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2371 PF10177.9 KRH93660.1 - 0.022 15.0 0.4 0.031 14.5 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Shisa PF13908.6 KRH93660.1 - 0.048 13.9 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 KRH93660.1 - 0.079 13.9 0.2 0.13 13.1 0.2 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CoxIIa PF08113.11 KRH93660.1 - 0.26 11.1 4.4 0.4 10.5 4.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family DUF4834 PF16118.5 KRH93660.1 - 1.7 9.7 5.4 12 7.0 5.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) MAP17 PF15807.5 KRH93660.1 - 6.6 7.0 6.7 32 4.8 6.7 1.9 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DDE_Tnp_IS1595 PF12762.7 KRH93661.1 - 6.2e-11 42.5 1.2 7.9e-11 42.2 1.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Spike_rec_bind PF09408.10 KRH93661.1 - 0.038 13.7 1.2 0.045 13.5 1.2 1.1 1 0 0 1 1 1 0 Spike receptor binding domain gag-asp_proteas PF13975.6 KRH93663.1 - 4e-09 36.9 0.1 5.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH93663.1 - 3.1e-05 23.8 0.4 4.1e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH93663.1 - 5.9e-05 23.6 0.1 9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KRH93663.1 - 0.00032 20.5 0.1 0.00043 20.1 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 KRH93664.1 - 1.3e-18 67.3 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH93664.1 - 0.0042 16.9 0.4 0.0092 15.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase thumb domain rve PF00665.26 KRH93665.1 - 0.00044 20.4 0.0 0.00057 20.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93665.1 - 0.014 15.5 1.2 0.019 15.1 0.5 1.6 2 0 0 2 2 2 0 Integrase zinc binding domain MLVIN_C PF18697.1 KRH93666.1 - 0.00026 21.0 0.0 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-CCHC PF00098.23 KRH93667.1 - 6.3e-06 26.0 2.4 1.6e-05 24.7 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH93667.1 - 0.02 14.6 1.8 0.02 14.6 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle MnmE_helical PF12631.7 KRH93667.1 - 0.067 13.3 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain TFIIE_beta PF02186.15 KRH93667.1 - 0.09 13.1 1.0 0.29 11.4 1.0 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain RVT_1 PF00078.27 KRH93668.1 - 5.1e-25 88.3 0.4 6.1e-25 88.0 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoU_div PF01865.16 KRH93668.1 - 0.015 14.7 0.6 0.02 14.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 RT_RNaseH PF17917.1 KRH93669.1 - 6.3e-35 119.6 0.1 9.4e-35 119.1 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93669.1 - 7.7e-32 109.3 0.0 1.2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop PF01798.18 KRH93670.1 - 1.3e-22 80.5 0.1 1.8e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Pox_T4_N PF04491.12 KRH93674.1 - 0.035 14.0 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus DDE_3 PF13358.6 KRH93675.1 - 8.7e-21 74.2 0.0 1.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Arg_repressor PF01316.21 KRH93675.1 - 0.00016 21.4 0.6 0.00036 20.2 0.6 1.6 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DDE_1 PF03184.19 KRH93675.1 - 0.008 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_21 PF13276.6 KRH93675.1 - 0.042 14.0 2.5 0.1 12.7 0.6 2.2 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_Tc3_2 PF01498.18 KRH93675.1 - 0.099 12.9 1.4 0.25 11.6 1.4 1.7 1 0 0 1 1 1 0 Transposase DUF2457 PF10446.9 KRH93676.1 - 0.088 11.9 9.4 0.11 11.6 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_1 PF00583.25 KRH93678.1 - 3.6e-12 46.5 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRH93678.1 - 8.1e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KRH93678.1 - 4.9e-08 33.0 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KRH93678.1 - 5.6e-05 23.2 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KRH93678.1 - 0.00018 21.4 0.0 0.00043 20.2 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KRH93678.1 - 0.00038 20.0 3.8 0.00088 18.8 3.7 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_3 PF13302.7 KRH93678.1 - 0.0047 17.6 0.0 0.006 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuc_red_lgC PF02867.15 KRH93679.1 - 4.8e-175 583.0 0.0 1.9e-174 581.1 0.0 1.9 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KRH93679.1 - 3.6e-21 75.0 0.1 9.2e-21 73.6 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KRH93679.1 - 0.012 16.2 0.0 0.035 14.7 0.0 1.9 1 0 0 1 1 1 0 ATP cone domain GnsAB_toxin PF08178.11 KRH93679.1 - 0.08 12.9 0.3 6.1 6.9 0.0 2.9 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system GlutR_dimer PF00745.20 KRH93682.1 - 0.0037 17.7 9.6 0.41 11.1 0.5 4.5 3 1 1 4 4 4 1 Glutamyl-tRNAGlu reductase, dimerisation domain PTS_IIA PF02255.16 KRH93682.1 - 0.22 11.6 12.7 3.9 7.6 1.5 3.8 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit tRNA-synt_2 PF00152.20 KRH93682.1 - 0.22 10.6 3.5 2.8 6.9 0.2 2.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) ATP19 PF11022.8 KRH93682.1 - 0.55 10.7 6.4 1.6 9.2 0.4 3.2 2 1 0 2 2 2 0 ATP synthase subunit K ATG_C PF09333.11 KRH93682.1 - 0.67 10.3 7.6 0.42 11.0 1.1 3.4 3 1 0 3 3 3 0 Autophagy-related protein C terminal domain Mlh1_C PF16413.5 KRH93682.1 - 3.6 6.9 7.1 1.9 7.8 1.1 2.8 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus DKCLD PF08068.12 KRH93684.1 - 1.4e-20 73.1 0.2 7.2e-19 67.6 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KRH93684.1 - 1.8e-19 69.6 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 KRH93684.1 - 1.2e-18 67.9 1.3 1.4e-15 57.9 1.3 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 KRH93684.1 - 2.6e-15 56.1 0.8 5e-15 55.2 0.8 1.5 1 0 0 1 1 1 1 PUA domain DNA_pol_B PF00136.21 KRH93685.1 - 3.6e-72 243.6 10.5 1.7e-71 241.3 10.5 2.1 1 1 0 1 1 1 1 DNA polymerase family B zf-CHY PF05495.12 KRH93685.1 - 0.21 12.1 10.1 1.6 9.3 10.1 2.4 1 1 0 1 1 1 0 CHY zinc finger PhnA_Zn_Ribbon PF08274.12 KRH93685.1 - 3 7.9 5.0 30 4.7 0.3 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IP_trans PF02121.18 KRH93686.1 - 8.6e-54 182.7 11.9 3e-52 177.7 11.9 2.1 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein Ribosomal_L29e PF01779.17 KRH93686.1 - 0.071 13.4 4.6 2.5 8.5 2.9 2.5 2 0 0 2 2 2 0 Ribosomal L29e protein family HTH_Tnp_Tc3_2 PF01498.18 KRH93690.1 - 1.1e-08 35.2 0.7 3.1e-06 27.4 0.1 2.2 1 1 1 2 2 2 2 Transposase PAX PF00292.18 KRH93690.1 - 0.0033 17.4 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.6 KRH93690.1 - 0.017 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix MCM PF00493.23 KRH93692.1 - 4.9e-38 130.5 0.5 1.3e-31 109.4 0.2 3.3 3 0 0 3 3 3 3 MCM P-loop domain MCM_OB PF17207.3 KRH93692.1 - 8.8e-07 28.8 0.0 2.4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 MCM OB domain FtsK_SpoIIIE PF01580.18 KRH93692.1 - 6.4e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 KRH93692.1 - 9.6e-05 22.2 0.6 0.00087 19.0 0.6 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 KRH93692.1 - 0.0001 22.5 0.2 0.00022 21.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain TrwB_AAD_bind PF10412.9 KRH93692.1 - 0.00012 21.1 0.2 0.00031 19.8 0.2 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 KRH93692.1 - 0.00026 20.4 2.0 0.098 12.0 0.0 2.8 2 1 1 3 3 2 2 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KRH93692.1 - 0.00079 18.6 1.8 0.0017 17.5 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_19 PF13245.6 KRH93692.1 - 0.0066 16.8 0.2 0.018 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KRH93692.1 - 0.0077 15.8 0.1 0.022 14.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 KRH93692.1 - 0.0086 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KRH93692.1 - 0.0096 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KRH93692.1 - 0.017 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KRH93692.1 - 0.018 15.3 2.6 0.025 14.8 0.5 2.4 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.6 KRH93692.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KRH93692.1 - 0.051 14.1 3.3 0.63 10.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 KRH93692.1 - 0.055 13.4 0.6 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KRH93692.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KRH93692.1 - 0.072 13.1 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF656 PF04920.12 KRH93692.1 - 0.092 12.7 0.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF656) AAA PF00004.29 KRH93692.1 - 0.095 13.1 0.1 0.27 11.7 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KRH93692.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 KRH93692.1 - 0.74 10.3 8.4 0.076 13.5 1.0 3.0 3 1 0 3 3 3 0 ABC transporter TFIIS_C PF01096.18 KRH93692.1 - 3.5 7.6 7.1 9.7 6.1 0.4 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DSHCT PF08148.12 KRH93694.1 - 5.3e-31 107.5 0.9 9.6e-31 106.7 0.2 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KRH93694.1 - 2.2e-19 69.9 0.2 6.5e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH93694.1 - 1.3e-12 48.1 0.2 4.8e-12 46.2 0.2 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KRH93694.1 - 3.3e-07 30.6 0.6 3.1e-06 27.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 KRH93694.1 - 2.5e-05 23.6 0.0 4.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) PhoH PF02562.16 KRH93694.1 - 0.0093 15.4 0.1 0.029 13.8 0.1 1.8 1 1 0 1 1 1 1 PhoH-like protein Paramyxo_C PF01692.18 KRH93694.1 - 0.053 12.9 0.2 0.14 11.5 0.2 1.7 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C IstB_IS21 PF01695.17 KRH93694.1 - 0.06 13.1 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein ANAPC15 PF15243.6 KRH93694.1 - 0.13 12.7 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TFIIB PF00382.19 KRH93695.1 - 3.5e-30 103.9 0.1 1.2e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KRH93695.1 - 1.7e-14 54.0 10.2 2e-13 50.5 10.2 2.3 1 1 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KRH93695.1 - 6.5e-05 22.4 0.5 0.00018 21.0 0.5 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KRH93695.1 - 0.00089 19.0 0.3 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 KRH93695.1 - 0.0013 18.8 0.1 0.0059 16.6 0.1 2.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cys_rich_CPCC PF14206.6 KRH93695.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich CPCC zf-ACC PF17848.1 KRH93695.1 - 0.33 11.1 2.8 0.78 9.9 2.8 1.7 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain LRR_6 PF13516.6 KRH93696.1 - 3.1e-06 26.8 16.4 0.72 10.1 0.3 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KRH93696.1 - 0.00012 22.1 9.8 1.9 9.3 0.1 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 KRH93696.1 - 0.0022 18.4 0.2 0.0022 18.4 0.2 5.0 2 1 3 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KRH93696.1 - 0.18 11.6 12.6 0.8 9.5 0.3 5.0 3 3 2 5 5 5 0 Leucine rich repeat FTH PF01827.27 KRH93696.1 - 0.75 9.6 14.6 2.6 7.8 0.6 3.7 3 1 1 4 4 4 0 FTH domain PGI PF00342.19 KRH93697.1 - 1.6e-142 475.5 2.2 2.2e-141 471.8 2.2 2.1 1 1 0 1 1 1 1 Phosphoglucose isomerase Usp PF00582.26 KRH93697.1 - 2.3 8.7 0.0 2.3 8.7 0.0 3.3 2 1 0 2 2 2 0 Universal stress protein family BIR PF00653.21 KRH93698.1 - 1.1e-16 61.2 4.7 8.2e-12 45.6 0.5 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DmpG_comm PF07836.11 KRH93699.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 DmpG-like communication domain HSP90 PF00183.18 KRH93701.1 - 7.1e-13 48.3 9.1 3.5e-11 42.7 2.6 2.3 2 0 0 2 2 2 2 Hsp90 protein 14-3-3 PF00244.20 KRH93701.1 - 0.088 12.3 2.4 0.12 11.9 0.2 2.0 2 0 0 2 2 2 0 14-3-3 protein GDPD PF03009.17 KRH93702.1 - 2.2e-21 76.8 1.4 7.9e-21 74.9 1.4 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Fungal_lectin_2 PF18647.1 KRH93702.1 - 0.11 13.0 0.6 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 Alpha-galactosyl-binding fungal lectin USP19_linker PF16602.5 KRH93703.1 - 0.53 10.8 11.3 1.6 9.3 0.5 3.7 1 1 3 4 4 4 0 Linker region of USP19 deubiquitinase DDE_Tnp_IS1595 PF12762.7 KRH93706.1 - 0.0011 19.0 0.0 0.004 17.2 0.0 1.8 2 0 0 2 2 2 1 ISXO2-like transposase domain Brr6_like_C_C PF10104.9 KRH93707.1 - 1.6e-24 86.2 3.7 2.1e-24 85.8 3.7 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Exo_endo_phos PF03372.23 KRH93708.1 - 5.8e-09 35.8 0.0 5.6e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KRH93708.1 - 0.00015 21.6 0.0 0.59 10.0 0.0 2.7 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase HTH_38 PF13936.6 KRH93708.1 - 0.15 11.8 0.0 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain ArlS_N PF18719.1 KRH93709.1 - 0.04 14.1 1.4 0.046 13.9 0.5 1.6 2 1 0 2 2 2 0 ArlS sensor domain B1 PF02246.15 KRH93709.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein L b1 domain DUF3365 PF11845.8 KRH93710.1 - 0.069 13.5 0.3 0.075 13.3 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) FlaC_arch PF05377.11 KRH93710.1 - 0.13 12.6 5.9 0.3 11.5 1.6 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KRH93710.1 - 0.76 9.6 11.8 1.7 8.5 5.7 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF5087 PF17006.5 KRH93711.1 - 3.6e-22 79.3 21.5 3e-15 56.5 1.9 3.5 3 2 0 3 3 3 2 Domain of unknown function (DUF5087) Imm17 PF15562.6 KRH93711.1 - 0.033 14.0 0.4 0.066 13.1 0.4 1.4 1 0 0 1 1 1 0 Immunity protein 17 Torsin PF06309.11 KRH93711.1 - 0.073 13.2 0.6 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Torsin RasGAP_C PF03836.15 KRH93711.1 - 0.61 10.2 8.0 0.49 10.5 5.8 1.9 2 0 0 2 2 2 0 RasGAP C-terminus RabGAP-TBC PF00566.18 KRH93713.1 - 2.8e-30 105.6 12.7 7e-28 97.8 1.6 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Pkinase PF00069.25 KRH93714.1 - 2.7e-30 105.6 2.9 2.7e-30 105.6 2.9 5.1 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93714.1 - 7.4e-16 58.2 0.5 4.5e-08 32.7 0.1 2.8 2 0 0 2 2 2 2 Protein tyrosine kinase Prok-RING_1 PF14446.6 KRH93714.1 - 2.3e-05 24.2 5.8 7.7e-05 22.5 5.8 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 KRH93714.1 - 0.016 15.1 10.1 0.062 13.2 10.2 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KRH93714.1 - 0.042 13.4 5.8 0.12 11.9 5.8 1.9 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KRH93714.1 - 9.6 6.2 7.9 26 4.8 7.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 KRH93716.1 - 4.7e-26 91.5 0.3 2.8e-25 89.0 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 KRH93716.1 - 3.2e-25 88.2 0.2 7.3e-25 87.0 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 KRH93716.1 - 3.3e-06 27.4 0.4 7.2e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KRH93716.1 - 0.00016 21.6 0.5 0.005 16.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KRH93716.1 - 0.0002 21.4 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LytTR PF04397.15 KRH93716.1 - 0.031 14.5 0.4 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 LytTr DNA-binding domain G-alpha PF00503.20 KRH93716.1 - 0.14 11.3 0.1 0.14 11.3 0.1 2.1 3 0 0 3 3 3 0 G-protein alpha subunit FtsH_ext PF06480.15 KRH93717.1 - 5.6 7.4 7.3 1.2e+02 3.1 7.3 2.4 1 1 0 1 1 1 0 FtsH Extracellular Metallophos PF00149.28 KRH93718.1 - 4.3e-15 56.8 4.5 2.8e-14 54.1 0.7 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase YABBY PF04690.13 KRH93718.1 - 1.6 9.3 7.8 2.1 8.9 0.2 2.9 2 1 0 2 2 2 0 YABBY protein CIAPIN1 PF05093.13 KRH93719.1 - 3.7e-13 49.8 13.1 2.7e-12 47.1 12.6 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4915 PF16261.5 KRH93720.1 - 0.019 14.2 0.6 0.12 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4915) DUF3800 PF12686.7 KRH93721.1 - 4.1 8.0 9.6 5.9e+02 1.1 9.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) GNAT_acetyltr_2 PF13718.6 KRH93722.1 - 8.2e-36 123.5 0.0 1.7e-33 116.0 0.0 2.2 1 1 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KRH93722.1 - 4.4e-06 26.6 0.8 1e-05 25.3 0.8 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.7 KRH93722.1 - 0.0044 17.4 0.1 0.011 16.2 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Exo_endo_phos PF03372.23 KRH93723.1 - 0.00031 20.3 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.24 KRH93724.1 - 1.7e-24 86.7 0.0 4.1e-24 85.4 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 EF-hand_1 PF00036.32 KRH93726.1 - 0.42 10.3 0.1 0.42 10.3 0.1 2.3 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KRH93726.1 - 0.61 10.2 0.1 0.61 10.2 0.1 2.2 3 0 0 3 3 3 0 EF-hand domain FAM176 PF14851.6 KRH93729.1 - 0.025 14.3 2.8 0.033 13.9 2.7 1.4 1 1 0 1 1 1 0 FAM176 family DUF1682 PF07946.14 KRH93729.1 - 0.03 13.6 7.9 0.04 13.1 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MAP17 PF15807.5 KRH93729.1 - 0.03 14.6 3.0 0.043 14.1 3.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SID-1_RNA_chan PF13965.6 KRH93729.1 - 0.09 11.2 2.6 0.093 11.1 2.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 KRH93729.1 - 0.1 11.8 1.5 0.1 11.8 1.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter E_Pc_C PF06752.12 KRH93729.1 - 0.15 12.2 0.5 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Pal1 PF08316.11 KRH93729.1 - 0.26 12.0 3.0 0.35 11.6 3.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Connexin PF00029.19 KRH93729.1 - 0.51 10.1 2.3 0.58 9.9 2.3 1.2 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 KRH93729.1 - 0.53 9.3 1.3 0.59 9.1 1.3 1.1 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 KRH93729.1 - 0.76 8.5 1.9 0.79 8.4 1.9 1.1 1 0 0 1 1 1 0 Ureide permease ETRAMP PF09716.10 KRH93729.1 - 2.1 8.5 11.5 6.3 6.9 10.8 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Beta-Casp PF10996.8 KRH93732.1 - 2e-29 102.1 0.6 6e-29 100.5 0.1 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KRH93732.1 - 4.1e-25 88.4 0.4 4.7e-24 84.9 0.3 2.5 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KRH93732.1 - 2.8e-15 56.0 0.0 7.5e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KRH93732.1 - 1.6e-13 51.1 0.2 5.8e-13 49.3 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KRH93732.1 - 1e-10 41.5 0.1 3.5e-10 39.7 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KRH93732.1 - 3.5e-05 23.1 0.2 0.00015 21.1 0.2 2.1 1 0 0 1 1 1 1 Putative beta-lactamase-like family Ndc1_Nup PF09531.10 KRH93732.1 - 2 7.0 6.7 2.9 6.5 6.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40_like PF17005.5 KRH93733.1 - 2.7e-15 56.5 22.2 9.8e-08 31.7 3.7 3.3 1 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 KRH93733.1 - 0.019 15.3 0.0 0.79 10.1 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIE_beta PF02186.15 KRH93734.1 - 4.8e-14 52.4 2.3 1e-13 51.4 0.6 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 KRH93734.1 - 2e-07 30.6 1.5 1e-06 28.3 0.1 2.7 3 1 0 3 3 3 1 TFA2 Winged helix domain 2 zf-CSL PF05207.13 KRH93737.1 - 0.04 13.6 0.6 0.073 12.8 0.6 1.5 1 0 0 1 1 1 0 CSL zinc finger Trehalase_Ca-bi PF07492.11 KRH93738.1 - 0.83 9.4 2.5 8.6 6.2 0.5 2.2 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain RT_RNaseH PF17917.1 KRH93739.1 - 1.1e-26 93.2 0.0 1.4e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93739.1 - 4.8e-19 68.2 0.0 6.8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3850 PF12961.7 KRH93739.1 - 0.058 13.4 0.3 0.089 12.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) CreD PF06123.12 KRH93741.1 - 0.034 12.9 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD HNOB PF07700.15 KRH93741.1 - 0.049 13.6 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Haem-NO-binding BRCT_2 PF16589.5 KRH93742.1 - 6.7e-07 29.6 5.8 0.016 15.6 0.1 4.1 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KRH93742.1 - 2.5e-06 27.3 0.2 0.00024 21.0 0.0 3.5 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.26 KRH93742.1 - 1.3e-05 25.4 14.9 0.00083 19.7 0.1 5.9 6 0 0 6 6 6 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KRH93742.1 - 0.058 13.7 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain zf-C2H2_3rep PF18868.1 KRH93742.1 - 2.7 8.7 5.2 18 6.0 0.4 2.9 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Cbl_N3 PF02762.14 KRH93743.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain EAV_GP5 PF15981.5 KRH93743.1 - 0.85 10.1 6.0 45 4.6 0.0 4.2 4 1 0 4 4 4 0 Envelope glycoprotein GP 5 of equine arteritis virus IBN_N PF03810.19 KRH93745.1 - 0.0002 21.2 0.0 0.00093 19.1 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KRH93745.1 - 0.0071 16.4 2.8 0.0071 16.4 2.8 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KRH93745.1 - 0.022 15.0 0.1 14 6.3 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 KRH93745.1 - 0.21 12.2 0.0 24 5.6 0.0 2.6 1 1 1 2 2 2 0 HEAT-like repeat DDE_1 PF03184.19 KRH93746.1 - 0.027 14.1 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease IL17R_fnIII_D2 PF16578.5 KRH93747.1 - 0.065 13.8 1.1 0.088 13.3 0.1 1.8 2 0 0 2 2 2 0 Interleukin 17 receptor D DUF2642 PF10842.8 KRH93748.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) DUF2956 PF11169.8 KRH93750.1 - 0.095 12.9 2.3 0.099 12.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) LRR_4 PF12799.7 KRH93752.1 - 3.8e-19 68.5 37.2 3.7e-06 27.2 4.0 5.9 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KRH93752.1 - 2.9e-14 52.5 29.8 0.00061 19.5 2.2 5.2 2 2 3 5 5 5 5 Leucine rich repeat FNIP PF05725.12 KRH93752.1 - 5.9e-09 35.9 0.0 0.0012 19.0 0.0 4.6 3 2 0 3 3 3 2 FNIP Repeat LRR_6 PF13516.6 KRH93752.1 - 3.3e-07 29.8 11.8 9.8 6.5 0.1 8.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.6 KRH93752.1 - 1.5e-06 27.8 17.1 1.7e-05 24.4 4.2 3.6 1 1 2 3 3 3 3 Leucine-rich repeat RVT_1 PF00078.27 KRH93757.1 - 6e-26 91.3 0.5 2e-25 89.6 0.5 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH93757.1 - 2.5e-25 88.8 0.2 9.9e-25 86.9 0.2 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93757.1 - 3e-25 88.2 0.2 9.5e-25 86.5 0.2 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93757.1 - 3e-17 62.9 0.0 5.1e-16 58.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 KRH93757.1 - 6.2e-10 39.5 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH93757.1 - 1.2e-09 38.7 0.0 2.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH93757.1 - 0.00025 20.8 0.0 0.00077 19.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH93757.1 - 0.00029 20.6 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 KRH93757.1 - 0.0004 20.4 0.4 0.0004 20.4 0.4 2.1 2 0 0 2 2 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 KRH93757.1 - 0.0017 18.1 0.1 0.0055 16.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain CIDE-N PF02017.15 KRH93757.1 - 0.015 15.3 0.3 0.045 13.8 0.3 1.8 1 0 0 1 1 1 0 CIDE-N domain rve_3 PF13683.6 KRH93757.1 - 0.064 13.0 0.0 1.1 9.1 0.0 3.1 2 0 0 2 2 2 0 Integrase core domain RVP PF00077.20 KRH93757.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_S13 PF00416.22 KRH93757.1 - 0.95 9.9 7.5 1.3 9.5 0.2 3.5 3 1 0 3 3 3 0 Ribosomal protein S13/S18 EF-hand_11 PF08976.11 KRH93758.1 - 0.054 14.4 0.2 0.26 12.2 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain RVT_1 PF00078.27 KRH93767.1 - 2.5e-26 92.6 0.6 5.5e-26 91.4 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93767.1 - 3.4e-26 91.2 0.0 9.3e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93767.1 - 4e-26 91.3 0.0 1.1e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93767.1 - 1.6e-16 60.6 0.0 3.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93767.1 - 1.3e-06 28.4 0.2 4e-06 26.8 0.2 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_thumb PF06817.14 KRH93767.1 - 0.0064 16.3 0.2 0.018 14.9 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain zf-BED PF02892.15 KRH93769.1 - 0.034 14.2 0.7 0.086 12.9 0.7 1.7 1 0 0 1 1 1 0 BED zinc finger RabGAP-TBC PF00566.18 KRH93770.1 - 3.4e-34 118.4 26.3 3e-33 115.3 22.0 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain eIF3g PF12353.8 KRH93770.1 - 0.37 11.2 3.5 0.23 11.8 1.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Nup188 PF10487.9 KRH93775.1 - 0.0011 16.9 0.0 0.0011 16.9 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 PB1 PF00564.24 KRH93775.1 - 0.023 14.6 0.2 0.16 11.9 0.1 2.3 2 0 0 2 2 2 0 PB1 domain Bromodomain PF00439.25 KRH93778.1 - 2.9e-05 24.1 1.9 5.8e-05 23.1 0.8 2.2 2 1 0 2 2 2 1 Bromodomain SbsC_C PF18058.1 KRH93778.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.6 3 1 0 3 3 3 0 SbsC C-terminal domain DIPSY PF11763.8 KRH93778.1 - 1.2 9.3 4.3 12 6.1 0.0 2.6 3 0 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal GTP_EFTU PF00009.27 KRH93779.1 - 3e-28 98.7 0.9 2.2e-27 95.9 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 KRH93779.1 - 1e-15 57.3 2.4 1.4e-15 56.9 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 IF-2 PF11987.8 KRH93779.1 - 9.2e-15 54.7 5.3 2.8e-14 53.1 5.3 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KRH93779.1 - 2.5e-12 47.0 1.4 9.8e-08 32.3 0.1 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Roc PF08477.13 KRH93779.1 - 1.1e-05 25.7 0.0 3.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KRH93779.1 - 5.9e-05 23.1 0.1 5.9e-05 23.1 0.1 3.6 4 1 0 4 4 4 1 50S ribosome-binding GTPase Ras PF00071.22 KRH93779.1 - 0.01 15.4 0.0 0.044 13.4 0.0 2.2 1 1 0 1 1 1 0 Ras family DUF1796 PF08795.10 KRH93779.1 - 0.027 14.4 1.5 0.05 13.6 0.0 2.1 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) AAA_22 PF13401.6 KRH93779.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain IF-2B PF01008.17 KRH93780.1 - 0.046 12.9 1.9 0.085 12.1 1.9 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family SOBP PF15279.6 KRH93780.1 - 9.8 6.7 18.9 16 6.0 18.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ATPase PF06745.13 KRH93782.1 - 0.012 14.9 0.7 0.034 13.5 0.7 1.7 1 0 0 1 1 1 0 KaiC DASH_Duo1 PF08651.10 KRH93782.1 - 0.014 15.1 4.6 0.031 14.1 1.2 2.6 2 1 0 2 2 2 0 DASH complex subunit Duo1 ICAP-1_inte_bdg PF10480.9 KRH93782.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Beta-1 integrin binding protein HEPN PF05168.14 KRH93782.1 - 0.17 12.0 1.6 16 5.7 0.1 2.4 2 0 0 2 2 2 0 HEPN domain S-AdoMet_synt_C PF02773.16 KRH93783.1 - 1.1e-55 187.4 0.0 2e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KRH93783.1 - 3.2e-30 104.8 0.0 7.8e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KRH93783.1 - 2.6e-24 85.7 0.1 6.8e-24 84.4 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KRH93783.1 - 0.019 13.8 0.6 0.051 12.4 0.6 1.7 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Copine PF07002.16 KRH93784.1 - 0.0073 15.8 0.1 0.024 14.1 0.0 2.1 2 0 0 2 2 2 1 Copine DUF3023 PF11224.8 KRH93784.1 - 0.012 15.4 0.0 0.04 13.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) Reprolysin PF01421.19 KRH93784.1 - 0.031 14.2 0.1 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease Reprolysin_4 PF13583.6 KRH93784.1 - 0.043 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fungal_TACC PF12709.7 KRH93784.1 - 1.4 9.4 7.3 10 6.6 3.3 3.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Ribosomal_L37ae PF01780.19 KRH93785.1 - 3.3e-31 107.2 6.7 3.6e-31 107.1 6.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KRH93785.1 - 0.0033 17.4 5.2 0.0052 16.7 5.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 KRH93785.1 - 0.019 15.4 6.5 0.12 12.9 2.9 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KRH93785.1 - 0.048 13.8 1.4 0.08 13.1 1.0 1.6 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KRH93785.1 - 0.053 13.5 2.0 0.067 13.1 1.3 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.15 KRH93785.1 - 0.059 13.4 0.9 0.059 13.4 0.9 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 KRH93785.1 - 0.088 12.2 4.7 1 8.8 4.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Prok-RING_4 PF14447.6 KRH93785.1 - 0.11 12.4 0.4 0.11 12.4 0.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-BED PF02892.15 KRH93785.1 - 0.15 12.1 6.5 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger DDE_Tnp_IS1595 PF12762.7 KRH93787.1 - 3.3e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.14 KRH93787.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Transposase IS66 family DUF3906 PF13046.6 KRH93790.1 - 0.018 15.2 0.1 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) SAC3_GANP PF03399.16 KRH93791.1 - 1.1e-42 146.4 7.5 3.3e-25 89.1 4.4 2.5 2 0 0 2 2 2 2 SAC3/GANP family ORC6 PF05460.13 KRH93791.1 - 0.0076 15.6 4.2 0.013 14.8 4.2 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Homeodomain PF00046.29 KRH93793.1 - 2.2e-20 72.2 0.5 2.2e-20 72.2 0.5 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KRH93793.1 - 0.0067 16.3 0.0 0.0067 16.3 0.0 2.6 3 0 0 3 3 3 1 Homeobox KN domain DUF1510 PF07423.11 KRH93793.1 - 0.049 13.8 0.4 0.049 13.8 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1510) DUF2981 PF11200.8 KRH93793.1 - 1 9.0 3.7 1.2 8.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SNF2_N PF00176.23 KRH93794.1 - 6.6e-45 153.3 2.6 1.5e-34 119.3 0.0 3.3 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KRH93794.1 - 7e-19 68.2 0.4 5.1e-18 65.4 0.0 2.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH93794.1 - 8.8e-07 29.1 1.5 5.9e-06 26.4 0.1 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KRH93794.1 - 4.6e-06 26.4 4.3 4.6e-06 26.4 4.3 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KRH93794.1 - 1.6e-05 24.3 0.0 3.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_2 PF13639.6 KRH93794.1 - 0.00026 21.3 4.8 0.00026 21.3 4.8 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KRH93794.1 - 0.00034 20.4 5.4 0.00034 20.4 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH93794.1 - 0.001 19.0 6.4 0.001 19.0 6.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KRH93794.1 - 0.0026 17.7 4.9 0.0026 17.7 4.9 2.4 2 1 0 2 2 1 1 RING-type zinc-finger DEAD PF00270.29 KRH93794.1 - 0.0091 15.8 0.1 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 KRH93794.1 - 0.01 15.7 3.8 0.01 15.7 3.8 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 CEBP_ZZ PF16366.5 KRH93794.1 - 1.4 9.2 6.7 31 4.9 3.8 2.9 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4 PF00097.25 KRH93794.1 - 8.6 6.3 16.8 0.026 14.4 6.5 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) PWWP PF00855.17 KRH93795.1 - 1.3e-05 25.5 0.0 1.3e-05 25.5 0.0 4.0 3 2 0 3 3 3 1 PWWP domain Otopetrin PF03189.13 KRH93795.1 - 0.011 14.6 0.1 0.07 11.9 0.1 2.0 1 1 0 1 1 1 0 Otopetrin UQ_con PF00179.26 KRH93796.1 - 2.3e-44 150.5 0.2 2.6e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KRH93796.1 - 1.3e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KRH93796.1 - 2.3e-05 24.6 0.1 4.3e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 KRH93796.1 - 0.023 14.6 0.2 0.054 13.3 0.2 1.6 1 1 0 1 1 1 0 UEV domain RNB PF00773.19 KRH93797.1 - 1.1e-74 251.7 6.6 2.3e-74 250.7 6.6 1.6 1 0 0 1 1 1 1 RNB domain Nucleoporin_FG PF13634.6 KRH93798.1 - 2.1 9.2 26.8 1.2e+03 0.4 26.8 2.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region rve PF00665.26 KRH93800.1 - 8e-18 64.8 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93800.1 - 8.9e-06 25.7 3.6 1.5e-05 25.0 1.6 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 KRH93800.1 - 0.027 14.2 0.1 0.068 13.0 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain MLVIN_C PF18697.1 KRH93800.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Ricin_B_lectin PF00652.22 KRH93802.1 - 0.00054 20.2 0.1 0.0011 19.2 0.0 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 KRH93802.1 - 0.01 15.4 1.3 0.018 14.7 0.4 1.9 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Cas_Cas1 PF01867.16 KRH93802.1 - 0.081 12.0 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Pentapeptide PF00805.22 KRH93803.1 - 6.2e-06 25.7 2.4 1.2e-05 24.8 1.6 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KRH93803.1 - 1.9e-05 24.7 4.8 3.1e-05 24.1 4.5 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KRH93803.1 - 0.01 16.0 1.9 0.017 15.3 1.9 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DENN PF02141.21 KRH93805.1 - 7.7e-10 39.0 0.5 3.5e-09 36.9 0.1 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Chordopox_RPO7 PF05864.12 KRH93805.1 - 0.017 15.4 0.7 0.06 13.6 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Pet100 PF09803.9 KRH93806.1 - 0.38 11.3 5.3 0.51 10.9 5.3 1.4 1 1 0 1 1 1 0 Pet100 GCP_C_terminal PF04130.13 KRH93808.1 - 0.002 17.6 5.8 0.019 14.4 0.2 2.9 2 1 0 3 3 3 2 Gamma tubulin complex component C-terminal XPG_I PF00867.18 KRH93809.1 - 9.9e-25 86.7 2.4 1.1e-24 86.5 0.2 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KRH93809.1 - 1.4e-21 76.9 0.1 3e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KRH93809.1 - 0.0032 18.0 0.1 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HSDR_N_2 PF13588.6 KRH93809.1 - 0.0093 16.0 0.1 0.062 13.3 0.1 2.4 3 0 0 3 3 3 1 Type I restriction enzyme R protein N terminus (HSDR_N) RecX PF02631.16 KRH93809.1 - 0.065 13.7 0.2 0.065 13.7 0.2 2.1 2 0 0 2 2 2 0 RecX family Fe_dep_repr_C PF02742.15 KRH93809.1 - 0.099 12.7 0.5 0.96 9.6 0.1 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Pex14_N PF04695.13 KRH93809.1 - 0.2 12.3 1.4 0.35 11.5 0.1 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EMC3_TMCO1 PF01956.16 KRH93809.1 - 0.54 10.0 2.9 1.2 8.9 2.9 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Sugar_tr PF00083.24 KRH93810.1 - 8.3e-14 51.3 6.9 2.1e-12 46.6 5.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Disaggr_assoc PF08480.10 KRH93811.1 - 0.069 13.0 4.7 0.032 14.1 1.3 2.1 2 1 0 2 2 2 0 Disaggregatase related RelB PF04221.12 KRH93812.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.2 4 0 0 4 4 4 0 RelB antitoxin TPT PF03151.16 KRH93813.1 - 1.1e-07 31.5 1.9 1.4e-07 31.2 1.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KRH93813.1 - 1.2e-06 28.8 3.0 1.7e-06 28.2 3.0 1.3 1 0 0 1 1 1 1 EamA-like transporter family PUNUT PF16913.5 KRH93813.1 - 0.003 16.9 3.8 0.0034 16.7 3.8 1.1 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport DUF1700 PF08006.11 KRH93813.1 - 0.016 14.7 3.2 0.019 14.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Zip PF02535.22 KRH93814.1 - 0.13 11.5 2.7 0.14 11.3 2.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter GRASP55_65 PF04495.14 KRH93816.1 - 6.6e-20 71.8 0.0 4.4e-14 53.0 0.0 2.4 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KRH93816.1 - 2.4e-06 27.8 0.0 0.027 14.8 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 KRH93816.1 - 0.0036 17.6 0.0 0.48 10.8 0.0 2.8 2 0 0 2 2 2 1 PDZ domain NAD_Gly3P_dh_C PF07479.14 KRH93817.1 - 3.1e-38 131.3 0.4 8.4e-38 129.8 0.3 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KRH93817.1 - 4.7e-28 98.2 0.0 7.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KRH93817.1 - 0.0076 16.8 0.3 5.1 7.7 0.2 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent IF2_N PF04760.15 KRH93817.1 - 0.041 13.7 0.2 1 9.3 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region 2TM PF13239.6 KRH93818.1 - 2.8 8.3 6.5 3.6 8.0 6.5 1.1 1 0 0 1 1 1 0 2TM domain DDE_3 PF13358.6 KRH93819.1 - 1.7e-25 89.5 0.5 4.8e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 KRH93819.1 - 0.0031 16.5 1.0 0.45 9.4 0.1 2.4 2 1 0 2 2 2 2 Rhodopirellula transposase DDE domain RE_ApaLI PF09499.10 KRH93819.1 - 0.013 15.2 0.6 0.023 14.4 0.6 1.4 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Arg_repressor PF01316.21 KRH93819.1 - 0.014 15.1 1.9 0.031 14.0 1.9 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF3800 PF12686.7 KRH93819.1 - 0.52 10.9 8.5 1.4 9.6 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) HTH_Tnp_Tc3_2 PF01498.18 KRH93819.1 - 0.75 10.1 5.2 1.3 9.3 3.8 2.1 2 0 0 2 2 2 0 Transposase ABC_tran PF00005.27 KRH93820.1 - 8.5e-25 87.9 0.0 2.2e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ATP-synt_ab PF00006.25 KRH93820.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KRH93820.1 - 0.02 14.8 1.7 0.59 10.0 0.1 3.1 3 0 0 3 3 3 0 NACHT domain SMC_N PF02463.19 KRH93820.1 - 0.069 12.6 5.8 3.7 6.9 0.0 2.9 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KRH93820.1 - 0.069 13.5 0.0 0.36 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain MS_channel PF00924.18 KRH93821.1 - 2.9e-19 69.4 0.3 6.6e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel CPDase PF07823.11 KRH93821.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF1242 PF06842.12 KRH93822.1 - 3.6e-09 36.3 1.6 4.5e-09 36.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) DUF167 PF02594.16 KRH93823.1 - 1.9e-22 79.2 1.4 2.5e-22 78.8 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Peptidase_C48 PF02902.19 KRH93825.1 - 2.4e-07 30.8 0.1 8.4e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KRH93825.1 - 0.00035 19.4 1.4 0.047 12.4 0.0 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase LupA PF18242.1 KRH93825.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.6 1 1 1 2 2 2 0 Legionella ubiquitin-specific protease A domain TFIIE_beta PF02186.15 KRH93826.1 - 0.071 13.4 3.2 0.098 13.0 1.8 1.9 2 1 0 2 2 2 0 TFIIE beta subunit core domain Peptidase_A25 PF03418.14 KRH93826.1 - 0.11 11.4 0.4 0.12 11.3 0.4 1.1 1 0 0 1 1 1 0 Germination protease Myb_DNA-bind_4 PF13837.6 KRH93826.1 - 0.35 11.3 3.3 1.1 9.7 3.4 1.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 KRH93827.1 - 0.002 17.6 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH93828.1 - 6.2e-16 58.6 0.2 7.9e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH93829.1 - 1.1e-16 60.7 0.0 1.2e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93829.1 - 1.2e-08 35.2 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93830.1 - 4.5e-18 65.6 0.0 8.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93830.1 - 4.4e-11 42.7 0.9 1.1e-10 41.5 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 KRH93830.1 - 0.014 15.2 0.1 0.059 13.2 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF1256 PF06866.11 KRH93830.1 - 0.063 12.7 0.6 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) ArsA_ATPase PF02374.15 KRH93831.1 - 2.7e-22 79.3 5.3 3.7e-21 75.6 5.3 1.9 1 1 0 1 1 1 1 Anion-transporting ATPase rve PF00665.26 KRH93832.1 - 7.9e-19 68.0 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH93832.1 - 4.9e-07 29.8 3.4 4.9e-07 29.8 3.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KRH93832.1 - 0.00066 19.8 0.8 0.00066 19.8 0.8 2.6 3 0 0 3 3 3 1 H2C2 zinc finger rve_3 PF13683.6 KRH93832.1 - 0.04 13.7 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DUF1758 PF05585.12 KRH93832.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RT_RNaseH_2 PF17919.1 KRH93833.1 - 1.6e-22 79.4 0.0 1.7e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93833.1 - 2.5e-15 56.7 0.0 2.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93834.1 - 1.9e-11 43.9 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH93834.1 - 0.00011 22.2 1.8 0.00024 21.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Peptidase_A25 PF03418.14 KRH93834.1 - 0.21 10.4 0.4 0.3 10.0 0.4 1.1 1 0 0 1 1 1 0 Germination protease M PF02370.16 KRH93834.1 - 0.43 11.3 3.3 1.8 9.4 3.3 2.1 1 0 0 1 1 1 0 M protein repeat zf-CCHC_4 PF14392.6 KRH93834.1 - 0.66 9.8 8.0 0.14 11.9 1.7 2.5 2 0 0 2 2 2 0 Zinc knuckle IFT20 PF14931.6 KRH93837.1 - 0.054 13.7 0.2 0.076 13.2 0.2 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 RT_RNaseH PF17917.1 KRH93838.1 - 5.7e-18 65.1 0.0 6.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93838.1 - 2.3e-17 62.9 0.0 2.6e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4537 PF15057.6 KRH93839.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) HEPN_RiboL-PSP PF18735.1 KRH93839.1 - 0.026 14.4 1.6 0.031 14.2 1.6 1.1 1 0 0 1 1 1 0 RiboL-PSP-HEPN Ndc1_Nup PF09531.10 KRH93844.1 - 0.0019 17.0 9.8 0.0019 17.0 9.8 1.5 2 0 0 2 2 2 1 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.11 KRH93844.1 - 6.4 5.1 41.7 0.49 8.8 36.4 1.7 2 0 0 2 2 2 0 Peptidase family S64 DUF2815 PF10991.8 KRH93845.1 - 0.045 13.7 0.2 0.053 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) DnaJ PF00226.31 KRH93845.1 - 0.079 13.1 2.4 0.25 11.5 0.4 2.6 2 1 0 2 2 2 0 DnaJ domain PCRF PF03462.18 KRH93845.1 - 0.28 11.0 2.3 0.34 10.8 2.3 1.1 1 0 0 1 1 1 0 PCRF domain DUF4638 PF15472.6 KRH93846.1 - 0.01 15.6 8.2 0.01 15.6 8.2 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4638) DUF1676 PF07898.13 KRH93846.1 - 0.079 13.0 0.5 0.079 13.0 0.5 4.8 3 2 0 3 3 3 0 Protein of unknown function (DUF1676) Chorein_N PF12624.7 KRH93848.1 - 3.8e-13 49.6 2.8 1e-12 48.2 1.6 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 PI3_PI4_kinase PF00454.27 KRH93850.1 - 2.5e-30 106.1 3.6 7.9e-28 97.9 0.2 3.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Ada3 PF10198.9 KRH93852.1 - 2.4e-05 24.5 6.6 8e-05 22.8 6.6 1.9 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DNA_pol3_delta2 PF13177.6 KRH93853.1 - 3.8e-11 43.0 0.5 3.8e-11 43.0 0.5 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit ATPase_2 PF01637.18 KRH93853.1 - 4.5e-06 26.7 4.0 4.5e-06 26.7 4.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KRH93853.1 - 0.00042 20.3 3.4 0.0015 18.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KRH93853.1 - 0.00045 20.1 3.6 0.00081 19.2 3.6 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KRH93853.1 - 0.0024 18.3 0.4 0.014 15.9 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KRH93853.1 - 0.0033 18.0 13.5 0.012 16.2 13.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH93853.1 - 0.0036 17.7 0.1 0.034 14.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KRH93853.1 - 0.0066 15.8 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KRH93853.1 - 0.0069 16.8 0.3 0.029 14.8 0.1 2.1 1 1 1 2 2 2 1 RNA helicase Rep_fac_C PF08542.11 KRH93853.1 - 0.008 16.6 0.1 0.03 14.7 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain ResIII PF04851.15 KRH93853.1 - 0.022 14.8 0.8 0.022 14.8 0.8 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 KRH93853.1 - 0.024 13.7 0.0 0.055 12.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KRH93853.1 - 0.029 14.7 1.1 0.083 13.2 0.3 2.1 1 1 1 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 KRH93853.1 - 0.041 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF815 PF05673.13 KRH93853.1 - 0.15 11.2 4.5 2.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KRH93853.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KRH93853.1 - 0.2 11.7 0.2 0.2 11.7 0.2 2.6 1 1 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 KRH93853.1 - 0.23 12.0 2.1 0.75 10.3 2.1 2.0 1 1 0 1 1 1 0 ABC transporter Ribosomal_60s PF00428.19 KRH93854.1 - 9e-09 35.8 4.9 1.1e-08 35.6 4.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Auxin_canalis PF05703.11 KRH93854.1 - 0.047 13.6 1.4 0.063 13.2 1.4 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF2999 PF11212.8 KRH93854.1 - 0.058 13.7 0.2 2.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) CEND1 PF15677.5 KRH93854.1 - 0.14 12.7 4.4 0.18 12.4 4.4 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Macscav_rec PF03523.13 KRH93855.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Macrophage scavenger receptor IZUMO PF15005.6 KRH93855.1 - 0.31 11.5 4.3 22 5.6 0.1 3.6 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Telomere_reg-2 PF10193.9 KRH93855.1 - 0.61 10.5 5.5 1.3 9.5 0.1 3.4 3 0 0 3 3 3 0 Telomere length regulation protein CLASP_N PF12348.8 KRH93855.1 - 3 7.4 7.4 0.42 10.1 0.5 3.0 4 0 0 4 4 4 0 CLASP N terminal DUF572 PF04502.13 KRH93856.1 - 2e-11 44.1 10.7 2.4e-11 43.9 10.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 KRH93856.1 - 0.00054 19.9 4.6 0.00068 19.6 4.6 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PARP PF00645.18 KRH93856.1 - 0.017 15.9 2.4 0.04 14.8 2.4 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Proteasome PF00227.26 KRH93857.1 - 4.1e-41 140.6 0.4 4.7e-41 140.4 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit Multi_ubiq PF14452.6 KRH93857.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Multiubiquitin RVT_1 PF00078.27 KRH93858.1 - 2.9e-43 148.0 0.0 4.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KRH93858.1 - 0.01 16.5 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf-RING_UBOX PF13445.6 KRH93859.1 - 1.5 8.9 5.0 1.8 8.7 3.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger S1FA PF04689.13 KRH93860.1 - 0.76 10.0 3.6 0.71 10.1 1.2 2.1 2 1 1 3 3 3 0 DNA binding protein S1FA HAD_2 PF13419.6 KRH93862.1 - 3.1e-06 27.4 0.8 3.5e-06 27.2 0.2 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase IL15 PF02372.15 KRH93862.1 - 0.0005 20.1 0.2 0.0011 19.0 0.2 1.6 1 0 0 1 1 1 1 Interleukin 15 DUF2608 PF11019.8 KRH93862.1 - 0.052 13.0 3.6 0.74 9.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2608) Hydrolase PF00702.26 KRH93862.1 - 0.069 13.4 0.0 2.4 8.4 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.27 KRH93865.1 - 3.9e-21 75.6 0.8 2.5e-20 72.9 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 KRH93870.1 - 2.5e-48 163.9 0.0 9.6e-46 155.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH93870.1 - 8.2e-15 54.3 0.0 7.1e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 KRH93870.1 - 5.1e-09 36.3 0.2 7.2e-06 26.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KRH93870.1 - 2.4e-08 33.9 0.0 4.6e-07 29.7 0.0 2.6 1 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KRH93870.1 - 8.6e-07 29.2 0.0 2.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KRH93870.1 - 2.2e-06 28.2 0.0 0.0046 17.4 0.0 2.9 2 1 1 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 KRH93870.1 - 3.9e-06 26.9 0.1 2.5e-05 24.3 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KRH93870.1 - 6.7e-06 26.7 4.3 7e-05 23.4 0.0 3.5 3 1 1 4 4 3 1 AAA domain AAA_22 PF13401.6 KRH93870.1 - 2.5e-05 24.6 0.2 0.0059 16.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KRH93870.1 - 5.9e-05 23.0 0.2 0.038 13.9 0.1 3.6 2 1 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KRH93870.1 - 8.7e-05 22.3 0.0 0.00026 20.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 KRH93870.1 - 0.00016 21.1 0.0 0.0005 19.5 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KRH93870.1 - 0.00016 22.0 0.0 0.0007 20.0 0.0 2.1 2 0 0 2 2 1 1 RNA helicase ATPase_2 PF01637.18 KRH93870.1 - 0.00019 21.4 0.5 0.037 13.9 0.1 3.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 KRH93870.1 - 0.00046 19.4 0.0 0.006 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KRH93870.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KRH93870.1 - 0.002 18.3 0.0 0.006 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 KRH93870.1 - 0.0032 17.4 0.1 0.0099 15.8 0.0 1.9 2 0 0 2 2 1 1 Rad17 P-loop domain Bac_DnaA PF00308.18 KRH93870.1 - 0.0038 17.1 0.0 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.17 KRH93870.1 - 0.0044 16.8 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 KRH93870.1 - 0.0045 17.0 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 KRH93870.1 - 0.0057 16.1 0.0 0.93 8.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 KRH93870.1 - 0.011 16.3 0.0 0.035 14.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KRH93870.1 - 0.021 14.0 0.1 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KRH93870.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KRH93870.1 - 0.023 14.1 0.1 0.12 11.7 0.0 2.2 2 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 KRH93870.1 - 0.025 14.3 0.1 0.91 9.2 0.0 3.1 2 2 1 4 4 4 0 Sigma-54 interaction domain AAA_17 PF13207.6 KRH93870.1 - 0.026 15.0 0.2 0.25 11.8 0.0 2.8 3 0 0 3 3 1 0 AAA domain Sigma54_activ_2 PF14532.6 KRH93870.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KRH93870.1 - 0.037 13.6 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KRH93870.1 - 0.046 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SNAD1 PF18744.1 KRH93870.1 - 0.06 13.2 0.2 0.22 11.4 0.0 2.0 3 0 0 3 3 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 Parvo_NS1 PF01057.17 KRH93870.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KRH93870.1 - 0.088 12.3 0.0 0.3 10.6 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KRH93870.1 - 0.088 12.6 0.0 0.36 10.6 0.0 2.0 3 0 0 3 3 1 0 P-loop containing region of AAA domain SKI PF01202.22 KRH93870.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.11 KRH93870.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KRH93870.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KRH93870.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KRH93870.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.8 2 2 0 2 2 1 0 AAA domain Ham1p_like PF01725.16 KRH93871.1 - 2.6e-28 99.2 0.0 2.9e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.16 KRH93872.1 - 1.2e-08 35.1 0.1 1.5e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Ham1 family DUF2959 PF11172.8 KRH93872.1 - 0.0043 17.2 0.1 0.0083 16.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) NEMO PF11577.8 KRH93872.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO PspB PF06667.12 KRH93872.1 - 0.92 9.6 4.2 0.4 10.8 1.5 1.7 2 0 0 2 2 2 0 Phage shock protein B RhoGAP PF00620.27 KRH93873.1 - 2.8e-07 30.5 6.7 0.0039 17.0 0.1 3.0 3 1 0 3 3 3 2 RhoGAP domain Retrotrans_gag PF03732.17 KRH93874.1 - 0.0029 17.8 1.3 0.011 16.0 0.2 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein Sigma70_ner PF04546.13 KRH93874.1 - 0.0044 16.9 1.5 0.0044 16.9 1.5 1.6 1 1 1 2 2 2 1 Sigma-70, non-essential region DUF445 PF04286.12 KRH93874.1 - 0.021 14.6 5.1 0.029 14.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CHDNT PF08073.12 KRH93876.1 - 0.0012 18.8 0.1 0.004 17.1 0.0 1.9 2 0 0 2 2 2 1 CHDNT (NUC034) domain HTH_23 PF13384.6 KRH93878.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.7 KRH93879.1 - 8.1e-13 48.7 0.9 1.6e-12 47.7 0.9 1.6 1 1 0 1 1 1 1 ISXO2-like transposase domain LAS2 PF15792.5 KRH93879.1 - 0.052 14.1 0.6 0.074 13.6 0.6 1.2 1 0 0 1 1 1 0 Lung adenoma susceptibility protein 2 rve PF00665.26 KRH93880.1 - 1.3e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RNA_pol_Rpb1_5 PF04998.17 KRH93881.1 - 5.3e-68 229.3 0.3 1.6e-67 227.8 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KRH93881.1 - 4.5e-60 202.7 0.1 8.7e-60 201.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KRH93881.1 - 2.6e-47 161.7 6.0 1.2e-46 159.6 6.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KRH93881.1 - 4.6e-20 71.6 1.9 1.1e-19 70.4 0.6 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 KRH93881.1 - 3.9e-09 36.6 0.6 2.5e-07 30.8 0.1 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 3 SIS_2 PF13580.6 KRH93881.1 - 0.14 12.2 0.4 0.39 10.7 0.4 1.8 1 0 0 1 1 1 0 SIS domain DUF719 PF05334.13 KRH93881.1 - 0.15 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Ribo_biogen_C PF04034.13 KRH93882.1 - 1.4e-47 160.6 0.1 1.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KRH93882.1 - 0.00034 20.4 0.5 0.00034 20.4 0.5 2.0 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI ParB_C PF18064.1 KRH93885.1 - 0.15 12.3 12.7 13 6.1 0.1 6.1 1 1 8 9 9 9 0 Centromere-binding protein ParB C-terminal Glutenin_hmw PF03157.13 KRH93885.1 - 4.3 5.6 46.2 0.8 8.0 38.8 2.1 1 1 1 2 2 2 0 High molecular weight glutenin subunit Glyco_transf_88 PF16849.5 KRH93885.1 - 10 4.9 12.0 2.8 6.8 0.7 3.3 1 1 4 5 5 5 0 Glycosyltransferase family 88 Lactamase_B_4 PF13691.6 KRH93887.1 - 2.3e-06 27.2 0.0 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease DUF3617 PF12276.8 KRH93888.1 - 0.14 12.5 5.1 0.14 12.5 3.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3617) Herpes_UL33 PF03581.13 KRH93888.1 - 0.17 12.3 1.1 6.5 7.2 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL33-like protein CP12 PF02672.15 KRH93888.1 - 0.25 12.1 6.4 0.42 11.4 0.6 2.4 2 1 1 3 3 3 0 CP12 domain DnaJ PF00226.31 KRH93890.1 - 0.05 13.7 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 DnaJ domain Pam16 PF03656.13 KRH93890.1 - 0.065 13.2 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Pam16 Pkinase PF00069.25 KRH93891.1 - 8.8e-45 153.1 2.3 1.7e-38 132.5 0.0 3.2 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93891.1 - 4.7e-23 81.8 0.2 2.6e-22 79.4 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH93891.1 - 5.5e-05 22.6 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KRH93891.1 - 0.0043 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DNA_pol3_finger PF17657.1 KRH93891.1 - 0.026 13.9 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha subunit finger domain Kdo PF06293.14 KRH93891.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KRH93891.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Slp PF03843.13 KRH93891.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family SIS PF01380.22 KRH93892.1 - 8.6e-50 168.0 0.1 1.6e-28 99.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KRH93892.1 - 1.8e-13 50.9 0.0 5e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KRH93892.1 - 7.2e-10 38.8 0.0 2.1e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KRH93892.1 - 1.8e-05 23.8 0.1 3.4e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KRH93892.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.8 1 1 0 1 1 1 1 SIS domain DUF3375 PF11855.8 KRH93892.1 - 0.85 8.5 2.4 2.4 7.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) RT_RNaseH_2 PF17919.1 KRH93894.1 - 6.9e-17 61.3 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH93894.1 - 4.1e-12 46.3 0.0 7.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PAZ PF02170.22 KRH93894.1 - 0.054 13.3 2.9 0.088 12.6 3.0 1.4 1 1 0 1 1 1 0 PAZ domain PSP1 PF04468.12 KRH93895.1 - 0.12 12.7 0.6 0.27 11.5 0.1 1.8 1 1 1 2 2 2 0 PSP1 C-terminal conserved region UPF1_Zn_bind PF09416.10 KRH93896.1 - 3.5e-15 56.3 6.8 8.5e-15 55.0 6.8 1.7 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) zf-B_box PF00643.24 KRH93896.1 - 5.1 7.3 17.6 0.068 13.3 4.5 2.8 3 0 0 3 3 3 0 B-box zinc finger PRK PF00485.18 KRH93899.1 - 9.4e-14 51.6 0.0 1.5e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KRH93899.1 - 0.00013 22.5 0.0 0.00022 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KRH93899.1 - 0.00041 20.3 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KRH93899.1 - 0.0097 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH93899.1 - 0.022 15.1 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 KRH93899.1 - 0.034 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 KRH93899.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRH93899.1 - 0.2 11.5 0.5 0.53 10.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pput2613-deam PF14427.6 KRH93900.1 - 0.037 13.9 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Pput_2613-like deaminase p12I PF12233.8 KRH93902.1 - 0.023 15.2 2.6 0.023 15.2 2.6 2.7 2 2 1 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein MCM PF00493.23 KRH93903.1 - 2.4e-93 311.4 0.4 3.6e-93 310.8 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH93903.1 - 4.9e-27 94.3 0.6 9.2e-27 93.4 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRH93903.1 - 1.1e-23 83.4 3.1 2.7e-21 75.8 3.1 2.6 1 1 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KRH93903.1 - 2.7e-07 30.2 0.0 8e-05 22.1 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRH93903.1 - 9.9e-05 22.4 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KRH93903.1 - 0.0042 16.9 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 KRH93903.1 - 0.016 15.8 2.9 0.018 15.7 0.2 2.5 2 2 1 3 3 3 0 MCM N-terminal domain Sigma54_activat PF00158.26 KRH93903.1 - 0.054 13.2 0.1 0.42 10.3 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain tRNA_U5-meth_tr PF05958.11 KRH93904.1 - 9.9e-11 41.2 0.3 9.9e-11 41.2 0.3 1.8 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 KRH93904.1 - 0.0079 16.2 0.1 0.0079 16.2 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH93904.1 - 0.028 14.2 0.1 0.028 14.2 0.1 3.5 3 2 0 3 3 3 0 Methyltransferase domain Met_10 PF02475.16 KRH93904.1 - 0.057 13.2 1.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein CAP18_C PF12153.8 KRH93904.1 - 6.3 6.8 7.7 0.26 11.2 0.2 2.6 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) CREPT PF16566.5 KRH93905.1 - 0.0035 17.5 3.7 0.006 16.8 3.7 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour E2F_TDP PF02319.20 KRH93905.1 - 0.37 10.9 2.6 0.61 10.2 0.7 2.2 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain OGG_N PF07934.12 KRH93906.1 - 0.65 10.1 6.4 30 4.7 1.7 4.1 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain CAP_GLY PF01302.25 KRH93907.1 - 1e-14 54.3 0.4 2.1e-14 53.2 0.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain PDCD7 PF16021.5 KRH93907.1 - 0.1 11.7 11.3 0.082 12.0 9.4 1.7 1 1 0 1 1 1 0 Programmed cell death protein 7 O-antigen_lig PF13425.6 KRH93907.1 - 2.3 6.9 8.7 3.5 6.3 8.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LSM PF01423.22 KRH93908.1 - 3.3e-06 26.7 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KRH93908.1 - 0.037 13.7 0.1 0.047 13.3 0.1 1.1 1 0 0 1 1 1 0 Hfq protein RIO1 PF01163.22 KRH93909.1 - 2e-44 151.5 9.0 3.3e-23 82.3 3.9 3.2 2 1 1 3 3 3 2 RIO1 family APH PF01636.23 KRH93909.1 - 0.12 12.3 0.0 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RT_RNaseH PF17917.1 KRH93911.1 - 2.5e-07 31.0 0.2 5.7e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH93912.1 - 1e-23 84.0 0.1 1.4e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH93913.1 - 0.0018 18.2 4.8 0.0044 17.0 4.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KRH93913.1 - 0.027 14.4 0.9 0.058 13.4 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_Tnp_IS1595 PF12762.7 KRH93914.1 - 6.2e-15 55.5 0.1 8.9e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain UPF0270 PF06794.12 KRH93914.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Wzy_C PF04932.15 KRH93915.1 - 2.7 7.6 10.5 45 3.7 9.8 2.0 1 1 1 2 2 2 0 O-Antigen ligase DUF5098 PF17023.5 KRH93916.1 - 4.4e-102 342.4 42.6 5e-102 342.3 42.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) SDH_sah PF01972.16 KRH93916.1 - 0.021 13.8 0.6 0.04 12.9 0.6 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Inh PF02974.14 KRH93916.1 - 0.092 12.8 0.7 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 Protease inhibitor Inh Aminotran_1_2 PF00155.21 KRH93917.1 - 6.9e-52 176.8 0.0 8.1e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KRH93917.1 - 0.0029 16.9 0.0 0.0067 15.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DpaA_N PF16924.5 KRH93917.1 - 0.044 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain eRF1_1 PF03463.15 KRH93918.1 - 4.4e-16 59.0 1.5 8.4e-16 58.1 1.5 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KRH93918.1 - 1.9e-07 31.5 1.8 2.4e-07 31.2 0.2 2.1 3 0 0 3 3 3 1 eRF1 domain 3 Thymidylat_synt PF00303.19 KRH93919.1 - 1e-106 356.0 0.0 1.1e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase MLVIN_C PF18697.1 KRH93921.1 - 0.0013 18.8 0.0 0.0031 17.5 0.0 1.8 2 1 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain XhlA PF10779.9 KRH93921.1 - 0.51 10.6 4.3 2.2 8.6 0.5 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF1837 PF08878.11 KRH93922.1 - 0.02 14.7 1.4 0.02 14.7 1.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1837) DnaGprimase_HBD PF16730.5 KRH93922.1 - 0.08 13.0 2.9 0.45 10.6 0.2 3.0 3 2 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain Pkinase PF00069.25 KRH93923.1 - 4.5e-43 147.5 0.0 6.4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93923.1 - 5.4e-21 75.0 0.0 8.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH93923.1 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 KRH93923.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 KRH93923.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adipokin_hormo PF06377.11 KRH93924.1 - 1.3e-06 28.6 9.2 1.7 9.1 0.0 6.9 1 1 7 10 10 10 3 Adipokinetic hormone Complex1_30kDa PF00329.19 KRH93924.1 - 1.6 9.4 12.8 9.4e+03 -2.8 12.8 3.7 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Herpes_UL73 PF03554.13 KRH93924.1 - 9.7 6.3 19.6 4.5 7.4 0.8 5.4 1 1 5 6 6 6 0 UL73 viral envelope glycoprotein DUF1056 PF06341.11 KRH93925.1 - 0.049 14.0 0.2 0.065 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) DUF35_N PF12172.8 KRH93928.1 - 0.0033 17.3 0.9 0.43 10.5 0.1 2.4 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 KRH93928.1 - 0.0061 16.5 3.6 0.01 15.7 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KRH93928.1 - 0.0082 16.2 2.0 2.2 8.5 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Methyltransf_13 PF08421.11 KRH93928.1 - 0.022 15.0 0.2 0.067 13.5 0.2 1.8 1 1 1 2 2 2 0 Putative zinc binding domain zinc_ribbon_5 PF13719.6 KRH93928.1 - 0.055 13.2 3.1 0.27 11.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 KRH93928.1 - 0.11 12.6 2.5 0.26 11.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 KRH93928.1 - 0.35 10.3 4.7 0.96 8.9 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.18 KRH93928.1 - 4.5 7.2 8.0 10 6.1 0.1 2.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) WD40 PF00400.32 KRH93929.1 - 3.8e-23 81.3 3.9 3.3e-05 24.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH93929.1 - 1.3e-10 41.5 0.7 0.066 13.5 0.0 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KRH93929.1 - 4.8e-07 29.4 5.8 0.00019 20.8 0.3 2.7 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 KRH93929.1 - 6.4e-05 21.8 0.4 0.012 14.3 0.0 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Frtz PF11768.8 KRH93929.1 - 0.0015 16.9 0.1 0.012 13.9 0.0 2.2 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 KRH93929.1 - 0.0037 15.8 0.9 0.0042 15.7 0.2 1.5 2 0 0 2 2 2 1 Utp8 family Nucleoporin_N PF08801.11 KRH93929.1 - 0.025 13.3 3.2 2 7.1 0.3 3.6 2 1 1 4 4 4 0 Nup133 N terminal like Ribosomal_L14 PF00238.19 KRH93930.1 - 5.8e-34 116.8 0.0 6.6e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RHD_dimer PF16179.5 KRH93931.1 - 0.022 14.8 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 Rel homology dimerisation domain DivIC PF04977.15 KRH93932.1 - 0.015 15.1 1.1 0.03 14.1 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1202 PF06717.11 KRH93932.1 - 0.026 14.0 0.1 0.03 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) LSM PF01423.22 KRH93933.1 - 3.9e-15 55.3 0.3 5.2e-15 54.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KRH93933.1 - 0.034 14.3 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF273 PF03314.14 KRH93934.1 - 0.023 14.3 0.7 0.032 13.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 RasGEF PF00617.19 KRH93935.1 - 1.4e-07 31.9 1.3 1.8e-07 31.5 0.4 1.6 2 0 0 2 2 2 1 RasGEF domain HECT PF00632.25 KRH93937.1 - 9.6e-23 81.1 5.5 3.4e-21 76.1 5.5 2.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KRH93937.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 WW domain DNA_ligase_ZBD PF03119.16 KRH93939.1 - 0.0005 20.0 0.6 0.00076 19.5 0.6 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain T4_baseplate PF12322.8 KRH93939.1 - 0.0043 16.5 0.8 0.0053 16.2 0.8 1.3 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.19 KRH93939.1 - 0.0086 15.8 1.2 0.017 14.9 1.2 1.5 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger zf-ACC PF17848.1 KRH93939.1 - 0.035 14.2 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KRH93939.1 - 0.041 13.3 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain TFCD_C PF12612.8 KRH93941.1 - 0.064 13.1 0.1 0.079 12.8 0.1 1.1 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal phage_tail_N PF08400.10 KRH93942.1 - 0.091 12.8 0.2 18 5.3 0.0 2.9 1 1 2 3 3 3 0 Prophage tail fibre N-terminal Antimicrobial19 PF08225.11 KRH93942.1 - 0.21 11.2 12.0 12 5.6 0.1 4.4 4 2 2 6 6 6 0 Pseudin antimicrobial peptide FRB_dom PF08771.11 KRH93942.1 - 0.26 11.7 2.9 1.3 9.5 0.1 2.3 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Epsilon_antitox PF08998.11 KRH93943.1 - 3.4 8.0 12.4 9.1e+03 -3.0 12.3 3.8 1 1 0 1 1 1 0 Bacterial epsilon antitoxin DUF349 PF03993.12 KRH93944.1 - 9.9 6.5 13.4 1e+02 3.3 13.4 2.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Methyltr_RsmB-F PF01189.17 KRH93945.1 - 2e-21 76.6 0.2 2.2e-12 47.1 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Radical_SAM_C PF16199.5 KRH93946.1 - 4.9e-32 109.8 0.1 1e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KRH93946.1 - 5.7e-19 69.1 0.0 1.7e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily DASH_Dad3 PF08656.10 KRH93949.1 - 0.023 14.8 1.7 0.088 12.9 0.3 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 Cas9_PI2 PF18070.1 KRH93949.1 - 0.22 12.3 3.5 1.2 10.0 3.5 2.3 1 1 0 1 1 1 0 CRISPR-Cas9 PI domain Mitofilin PF09731.9 KRH93950.1 - 0.76 8.5 33.7 1.1 8.0 33.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 KRH93950.1 - 3.2 6.8 44.6 5 6.1 44.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) S-AdoMet_synt_M PF02772.16 KRH93951.1 - 1e-13 51.6 0.0 1.8e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, central domain Suppressor_P21 PF11479.8 KRH93951.1 - 0.05 13.8 0.1 7.7 6.8 0.0 2.6 3 0 0 3 3 3 0 RNA silencing suppressor P21 C-terminal domain MoeA_C PF03454.15 KRH93951.1 - 0.095 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Efg1 PF10153.9 KRH93952.1 - 0.027 14.8 0.5 0.027 14.8 0.5 1.9 2 1 0 2 2 2 0 rRNA-processing protein Efg1 Rad60-SLD PF11976.8 KRH93953.1 - 2.6e-09 36.8 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KRH93953.1 - 0.00035 20.3 0.1 0.00047 19.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family CDC48_2 PF02933.17 KRH93953.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Ribosomal_60s PF00428.19 KRH93954.1 - 1.5e-12 48.0 0.3 1.7e-12 47.8 0.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mog1 PF04603.12 KRH93954.1 - 0.027 14.8 0.0 0.033 14.6 0.0 1.1 1 0 0 1 1 1 0 Ran-interacting Mog1 protein His_Phos_2 PF00328.22 KRH93955.1 - 2.3e-10 40.4 0.0 4.4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) rve PF00665.26 KRH93956.1 - 0.0059 16.8 0.1 0.01 16.0 0.1 1.4 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 KRH93957.1 - 1.8e-14 53.7 0.1 2.1e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3741 PF12552.8 KRH93957.1 - 0.023 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) eIF3g PF12353.8 KRH93958.1 - 0.0012 19.2 1.4 0.0012 19.2 1.4 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF2312 PF10073.9 KRH93959.1 - 0.0083 15.7 1.8 0.018 14.7 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2312) WHEP-TRS PF00458.20 KRH93959.1 - 0.052 13.7 1.8 0.063 13.4 0.7 1.7 2 0 0 2 2 2 0 WHEP-TRS domain Toprim_Crpt PF13342.6 KRH93959.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase RVT_1 PF00078.27 KRH93960.1 - 2.7e-30 105.5 0.2 3.6e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH93961.1 - 6.6e-33 113.1 0.2 1.1e-32 112.5 0.2 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93961.1 - 2e-22 79.1 0.0 4.9e-22 77.8 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_3 PF13456.6 KRH93961.1 - 0.002 17.9 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Zip PF02535.22 KRH93963.1 - 0.7 9.0 4.6 1.1 8.5 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KRH93963.1 - 5.2 5.9 9.6 10 4.9 9.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 KRH93963.1 - 6.9 4.8 19.8 0.24 9.6 14.0 1.5 2 0 0 2 2 2 0 CDC45-like protein RVT_1 PF00078.27 KRH93964.1 - 5.7e-27 94.7 0.3 1.1e-26 93.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH93964.1 - 1.3e-05 25.1 0.8 2.9e-05 24.0 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 KRH93964.1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KRH93964.1 - 0.022 15.3 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 KRH93965.1 - 3e-29 101.4 0.1 7.6e-29 100.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH93965.1 - 6.1e-22 77.5 0.2 1.8e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH93965.1 - 4.6e-12 46.2 0.0 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DUF424 PF04242.13 KRH93967.1 - 0.012 15.9 0.9 0.2 12.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF424) DUF3802 PF12290.8 KRH93969.1 - 0.0064 17.0 2.9 0.0083 16.6 1.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3802) UvsY PF11056.8 KRH93969.1 - 0.01 16.2 1.8 0.016 15.6 1.8 1.5 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF1192 PF06698.11 KRH93969.1 - 0.098 12.7 0.1 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF3573 PF12097.8 KRH93969.1 - 0.15 10.9 0.9 0.18 10.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1878 PF08963.10 KRH93969.1 - 0.17 12.4 5.7 3.8 8.0 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) BST2 PF16716.5 KRH93969.1 - 0.94 10.1 6.3 0.22 12.1 1.6 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 InvH PF04741.12 KRH93970.1 - 0.0024 17.8 0.3 0.0055 16.6 0.3 1.6 1 0 0 1 1 1 1 InvH outer membrane lipoprotein ATP-synt_C PF00137.21 KRH93971.1 - 1.2e-07 31.9 21.6 4.8e-05 23.6 3.3 2.5 3 0 0 3 3 3 2 ATP synthase subunit C FHIPEP PF00771.20 KRH93971.1 - 0.097 11.1 0.8 0.13 10.7 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family GIDA PF01134.22 KRH93971.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A PTPlike_phytase PF14566.6 KRH93973.1 - 2.9 8.0 8.3 26 4.9 4.9 3.3 2 1 1 3 3 3 0 Inositol hexakisphosphate Asp-B-Hydro_N PF05279.11 KRH93973.1 - 5.7 6.9 17.5 9.9 6.2 17.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_M17 PF00883.21 KRH93974.1 - 2e-97 326.2 0.0 3.9e-96 322.0 0.0 2.0 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3850 PF12961.7 KRH93975.1 - 0.046 13.8 0.2 0.057 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Imm-NTF2-2 PF15631.6 KRH93975.1 - 0.07 13.4 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein HEAT_EZ PF13513.6 KRH93976.1 - 6.6e-06 26.5 3.7 2.9 8.5 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat DUF948 PF06103.11 KRH93976.1 - 0.0057 16.9 13.9 10 6.4 0.1 5.4 1 1 4 5 5 5 2 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 KRH93976.1 - 0.04 14.5 22.4 6.7 7.4 0.9 5.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.12 KRH93976.1 - 0.11 12.4 11.8 18 5.4 0.2 4.7 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) DUF2524 PF10732.9 KRH93976.1 - 0.61 10.4 24.9 1.3 9.4 1.5 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2524) Mis12 PF05859.12 KRH93976.1 - 0.65 10.1 26.8 0.48 10.5 1.3 4.9 1 1 3 4 4 4 0 Mis12 protein Calici_coat_C PF08435.11 KRH93976.1 - 0.71 9.4 4.4 0.36 10.3 0.7 2.1 1 1 1 2 2 2 0 Calicivirus coat protein C-terminal SesA PF17107.5 KRH93976.1 - 0.98 9.6 28.8 2.3 8.5 0.7 6.0 3 1 4 7 7 7 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BIV_Env PF05858.12 KRH93976.1 - 1.6 6.8 5.0 2.9 6.0 5.0 1.5 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Vault_4 PF17796.1 KRH93976.1 - 1.7 8.7 7.4 90 3.3 0.2 4.4 4 0 0 4 4 4 0 Major Vault Protein repeat domain SLATT_5 PF18160.1 KRH93976.1 - 2.3 7.5 32.5 1.1 8.6 2.2 5.4 2 1 3 5 5 5 0 SMODS and SLOG-associating 2TM effector domain family 5 DPM3 PF08285.11 KRH93976.1 - 4.3 7.6 12.9 24 5.2 0.3 3.9 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Shugoshin_N PF07558.11 KRH93976.1 - 5.7 6.9 27.5 5.8 6.9 0.8 5.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region AFP_2 PF18815.1 KRH93978.1 - 0.72 10.1 3.6 5.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Spore_YpjB PF09577.10 KRH93980.1 - 0.02 14.7 0.5 0.02 14.7 0.5 1.8 2 1 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) BSP_II PF05432.11 KRH93982.1 - 9.2 5.9 37.9 11 5.6 37.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_M48_N PF16491.5 KRH93983.1 - 4.1e-48 163.7 22.2 4.1e-48 163.7 22.2 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KRH93983.1 - 1.5e-36 126.1 0.1 3e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 KRH93983.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.6 KRH93983.1 - 0.59 9.9 3.3 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Pkinase PF00069.25 KRH93984.1 - 6.7e-65 219.1 0.1 8e-65 218.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH93984.1 - 7.8e-34 117.1 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KRH93984.1 - 3e-06 26.4 1.9 3.3e-06 26.3 0.6 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KRH93984.1 - 8.5e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KRH93984.1 - 0.096 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2373 PF10180.9 KRH93985.1 - 0.057 13.3 1.4 2.9 7.8 0.3 2.5 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Flp_N PF03930.14 KRH93985.1 - 0.12 12.4 5.3 3.5 7.7 1.5 2.9 3 1 0 3 3 3 0 Recombinase Flp protein N-terminus Ras PF00071.22 KRH93987.1 - 2.2e-41 141.2 0.1 2.6e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH93987.1 - 8.4e-21 74.4 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH93987.1 - 2.6e-09 36.8 0.1 2.9e-09 36.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 KRH93987.1 - 0.0048 16.3 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein GTP_EFTU PF00009.27 KRH93987.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KRH93987.1 - 0.021 14.9 0.4 0.38 10.8 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KRH93987.1 - 0.027 14.8 0.0 5.6 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain YEATS PF03366.16 KRH93988.1 - 5.6e-15 55.1 7.9 1.9e-14 53.4 7.9 2.0 1 1 0 1 1 1 1 YEATS family UCH PF00443.29 KRH93988.1 - 0.31 10.5 5.4 0.38 10.2 5.4 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase YfhO PF09586.10 KRH93988.1 - 0.41 8.8 4.5 0.43 8.8 4.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO sCache_like PF16736.5 KRH93988.1 - 0.77 9.9 11.7 0.2 11.8 8.0 1.8 2 0 0 2 2 2 0 Single Cache-like Presenilin PF01080.17 KRH93988.1 - 0.86 8.3 3.9 1.2 7.9 3.9 1.1 1 0 0 1 1 1 0 Presenilin MutS_V PF00488.21 KRH93991.1 - 1.4e-46 158.9 3.8 3.1e-25 89.3 0.1 3.1 3 0 0 3 3 3 2 MutS domain V MutS_I PF01624.20 KRH93991.1 - 1.1e-28 99.7 0.2 4.1e-28 97.9 0.2 2.0 1 1 0 1 1 1 1 MutS domain I MutS_III PF05192.18 KRH93991.1 - 3.7e-09 37.1 4.8 3.7e-09 37.1 4.8 3.7 3 2 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KRH93991.1 - 2.1e-07 31.2 4.7 8.3e-07 29.3 4.7 2.1 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KRH93991.1 - 0.00027 21.5 0.0 0.00027 21.5 0.0 6.5 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.6 KRH93991.1 - 0.0032 17.2 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KRH93991.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.2 5 0 0 5 5 5 0 ABC transporter DUF5099 PF17025.5 KRH93993.1 - 6.4e-30 103.8 1.6 7.5e-30 103.5 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5099) TIP49 PF06068.13 KRH93994.1 - 1.1e-09 38.0 4.3 1e-06 28.2 2.8 3.0 1 1 1 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KRH93994.1 - 0.0016 18.8 0.0 0.18 12.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain TIP49_C PF17856.1 KRH93994.1 - 0.0047 17.0 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 AAA-lid domain TTC5_OB PF16669.5 KRH93994.1 - 0.018 14.7 0.9 0.08 12.6 0.3 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat protein 5 OB fold domain AAA_7 PF12775.7 KRH93994.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KRH93994.1 - 0.041 14.3 1.8 0.1 13.0 0.1 2.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KRH93994.1 - 0.093 12.8 5.9 0.19 11.7 0.1 3.6 2 2 3 5 5 5 0 AAA domain CDRT4 PF15213.6 KRH93995.1 - 0.073 13.7 2.9 0.32 11.6 1.0 2.4 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein NuA4 PF09340.10 KRH93996.1 - 2.3e-09 37.0 0.5 3.4e-09 36.4 0.5 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4208 PF13907.6 KRH93996.1 - 0.047 14.1 0.1 0.059 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) CCDC85 PF10226.9 KRH93996.1 - 0.05 13.3 0.0 0.05 13.3 0.0 1.1 1 0 0 1 1 1 0 CCDC85 family RNA_pol_L_2 PF13656.6 KRH93997.1 - 5.1e-15 55.0 0.3 2.8e-14 52.6 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C2 PF00168.30 KRH93998.1 - 2.4e-27 95.2 2.9 1e-17 64.3 0.1 5.3 5 0 0 5 5 5 2 C2 domain SMP_LBD PF17047.5 KRH93998.1 - 0.0077 15.7 0.3 2.4 7.6 0.1 2.5 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain SPC12 PF06645.13 KRH93998.1 - 1.1 9.4 3.7 2.5 8.3 3.7 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) CCDC106 PF15794.5 KRH93999.1 - 0.003 17.3 4.3 0.004 16.9 4.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Sec3_C PF09763.9 KRH93999.1 - 0.044 12.2 0.5 0.047 12.1 0.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 RNA_pol_Rpc4 PF05132.14 KRH93999.1 - 0.13 12.7 4.5 0.19 12.1 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 KRH93999.1 - 0.35 9.6 2.9 0.4 9.4 2.9 1.1 1 0 0 1 1 1 0 Presenilin MAP65_ASE1 PF03999.12 KRH93999.1 - 0.36 9.5 6.2 0.42 9.3 6.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Tim54 PF11711.8 KRH93999.1 - 0.43 9.3 6.4 0.56 8.9 6.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 KRH93999.1 - 0.48 10.0 18.5 0.67 9.5 18.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOG2 PF10428.9 KRH93999.1 - 1.1 8.4 10.9 1.1 8.3 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sox_N PF12444.8 KRH93999.1 - 1.3 10.2 9.0 2.5 9.3 9.0 1.4 1 0 0 1 1 1 0 Sox developmental protein N terminal Bindin PF02084.15 KRH93999.1 - 2.9 8.1 6.6 1.7 8.8 5.0 1.4 1 1 0 1 1 1 0 Bindin Coilin_N PF15862.5 KRH93999.1 - 3.2 7.6 11.4 4.3 7.2 11.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus Macoilin PF09726.9 KRH93999.1 - 4.9 5.6 8.4 5.7 5.4 8.4 1.0 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 KRH93999.1 - 5.8 6.9 13.2 8.3 6.4 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.13 KRH93999.1 - 7.1 5.3 8.9 9.3 4.9 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UCH PF00443.29 KRH94000.1 - 1.5e-07 31.2 3.4 4.4e-06 26.4 3.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Insulin_TMD PF17870.1 KRH94000.1 - 0.2 11.8 0.8 0.51 10.4 0.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RasGAP_C PF03836.15 KRH94001.1 - 1.4 9.0 32.0 0.092 12.9 14.0 5.4 3 1 2 5 5 5 0 RasGAP C-terminus CLAMP PF14769.6 KRH94001.1 - 6.9 7.2 12.0 0.64 10.5 0.3 4.4 5 1 0 5 5 5 0 Flagellar C1a complex subunit C1a-32 KIAA1430 PF13879.6 KRH94002.1 - 0.0091 16.7 6.5 0.0095 16.7 6.5 1.2 1 0 0 1 1 1 1 KIAA1430 homologue Retrotrans_gag PF03732.17 KRH94004.1 - 0.059 13.7 0.1 2 8.7 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein SNF2_N PF00176.23 KRH94006.1 - 9.5e-22 77.2 0.1 9.5e-22 77.2 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain HEAT PF02985.22 KRH94006.1 - 0.11 12.8 0.1 5.1 7.6 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Ac76 PF05814.11 KRH94007.1 - 0.014 15.4 3.6 0.014 15.4 3.6 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) Peptidase_M56 PF05569.11 KRH94007.1 - 0.41 9.8 12.0 0.37 9.9 6.3 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 ABC_tran PF00005.27 KRH94009.1 - 3e-07 31.0 0.0 8.1e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KRH94009.1 - 3.4e-05 23.8 0.1 8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KRH94009.1 - 0.0014 18.1 18.1 0.0014 18.1 18.1 3.1 2 1 1 3 3 3 2 ABC-2 type transporter SMC_N PF02463.19 KRH94009.1 - 0.0085 15.6 0.0 0.027 13.9 0.0 1.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KRH94009.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Vma12 PF11712.8 KRH94009.1 - 1.6 8.8 6.2 0.15 12.1 0.2 2.4 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ABC_tran PF00005.27 KRH94010.1 - 1.5e-13 51.4 0.0 2.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KRH94010.1 - 3e-05 24.0 0.1 4.2e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KRH94010.1 - 0.00016 22.1 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KRH94010.1 - 0.00033 20.9 0.1 0.0006 20.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 KRH94010.1 - 0.00098 19.7 2.1 0.0019 18.8 2.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KRH94010.1 - 0.001 19.1 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KRH94010.1 - 0.0015 19.1 0.1 0.0025 18.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 KRH94010.1 - 0.0019 17.3 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KRH94010.1 - 0.0027 17.4 0.5 0.0093 15.7 0.1 2.0 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 KRH94010.1 - 0.0033 17.4 0.2 0.0052 16.7 0.2 1.3 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KRH94010.1 - 0.004 17.5 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin PF02224.18 KRH94010.1 - 0.0048 16.7 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase NACHT PF05729.12 KRH94010.1 - 0.006 16.5 0.3 0.0089 16.0 0.3 1.3 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 KRH94010.1 - 0.0062 16.2 1.0 0.013 15.2 1.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 KRH94010.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Septin cobW PF02492.19 KRH94010.1 - 0.013 15.1 0.6 0.021 14.4 0.6 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KRH94010.1 - 0.017 15.4 0.7 0.028 14.6 0.7 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KRH94010.1 - 0.018 15.0 0.2 0.027 14.4 0.2 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 KRH94010.1 - 0.023 14.5 0.1 0.046 13.5 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 KRH94010.1 - 0.023 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KRH94010.1 - 0.025 14.4 0.4 0.042 13.6 0.4 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein PRK PF00485.18 KRH94010.1 - 0.03 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KRH94010.1 - 0.031 14.2 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 KRH94010.1 - 0.037 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KRH94010.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KRH94010.1 - 0.038 13.8 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase_2 PF01637.18 KRH94010.1 - 0.043 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KRH94010.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.6 KRH94010.1 - 0.048 13.8 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KRH94010.1 - 0.08 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Dynamin_N PF00350.23 KRH94010.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_30 PF13604.6 KRH94010.1 - 0.085 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KRH94010.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KRH94010.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KRH94010.1 - 0.12 12.0 0.3 0.25 10.9 0.2 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 KRH94010.1 - 0.12 11.8 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KRH94010.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KRH94010.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) U1snRNP70_N PF12220.8 KRH94016.1 - 0.025 15.2 1.1 0.032 14.9 1.1 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal U71 PF17474.2 KRH94018.1 - 0.0099 15.8 0.3 0.17 11.9 0.1 2.1 2 0 0 2 2 2 1 Tegument protein UL11 homolog Baculo_IE-1 PF05290.11 KRH94019.1 - 0.025 14.6 1.2 0.037 14.0 0.8 1.5 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) LON_substr_bdg PF02190.16 KRH94019.1 - 0.033 14.1 3.3 0.041 13.8 3.3 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain NPC1_N PF16414.5 KRH94019.1 - 0.055 13.0 0.4 0.062 12.8 0.4 1.2 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus COG2 PF06148.11 KRH94019.1 - 0.067 13.3 4.9 0.11 12.5 0.9 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_HK97_TLTM PF06120.11 KRH94019.1 - 0.068 12.3 3.5 0.08 12.1 3.5 1.0 1 0 0 1 1 1 0 Tail length tape measure protein zf-C4H2 PF10146.9 KRH94019.1 - 0.076 13.3 4.6 0.089 13.1 4.6 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3557 PF12078.8 KRH94019.1 - 0.16 11.9 4.4 0.2 11.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) KxDL PF10241.9 KRH94019.1 - 0.33 11.3 5.7 1.8 8.9 1.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein RNA_pol_Rpc34 PF05158.12 KRH94020.1 - 4.4e-21 75.6 11.8 5.6e-21 75.3 11.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit ESCRT-II PF05871.12 KRH94020.1 - 9e-05 22.7 4.1 0.012 15.8 0.0 3.1 1 1 2 3 3 3 2 ESCRT-II complex subunit HxlR PF01638.17 KRH94020.1 - 0.00021 21.1 1.9 0.1 12.5 0.1 2.5 2 0 0 2 2 2 2 HxlR-like helix-turn-helix Phage_sheath_1C PF17482.2 KRH94020.1 - 0.0085 16.0 5.9 0.41 10.6 1.8 2.4 2 0 0 2 2 2 2 Phage tail sheath C-terminal domain MarR PF01047.22 KRH94020.1 - 0.01 15.7 0.6 0.62 10.0 0.1 2.6 2 0 0 2 2 2 0 MarR family Rrf2 PF02082.20 KRH94020.1 - 0.091 13.1 0.4 1.7 9.0 0.1 2.5 1 1 0 2 2 2 0 Transcriptional regulator HTH_34 PF13601.6 KRH94020.1 - 0.15 12.2 4.2 0.25 11.5 0.5 2.7 3 0 0 3 3 3 0 Winged helix DNA-binding domain CXCR4_N PF12109.8 KRH94021.1 - 0.05 13.8 1.6 0.12 12.6 1.6 1.6 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal FAM110_C PF14160.6 KRH94021.1 - 8.8 7.5 11.0 0.29 12.2 2.6 2.4 1 1 1 2 2 2 0 Centrosome-associated C terminus Trehalase PF01204.18 KRH94022.1 - 2.6e-123 412.6 0.5 3.6e-121 405.5 0.5 2.3 1 1 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 KRH94022.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain PCDO_beta_N PF12391.8 KRH94023.1 - 1.5 8.5 5.3 1.4e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal MS_channel PF00924.18 KRH94024.1 - 2.8e-06 27.0 1.6 1.3e-05 24.9 1.6 2.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KRH94024.1 - 0.00081 18.8 0.7 0.0045 16.4 0.7 2.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KRH94024.1 - 0.001 18.8 2.2 0.0086 15.9 1.9 2.8 1 1 1 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KRH94024.1 - 0.041 13.7 0.2 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair E1-E2_ATPase PF00122.20 KRH94024.1 - 6 6.4 6.5 6 6.3 0.5 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Glutaredoxin PF00462.24 KRH94026.1 - 7e-10 39.0 0.0 1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KRH94026.1 - 0.0012 19.2 0.0 0.0019 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FANCL_C PF11793.8 KRH94026.1 - 0.063 13.5 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain Thioredoxin_9 PF14595.6 KRH94026.1 - 0.065 13.0 0.3 0.083 12.7 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin GST_N_2 PF13409.6 KRH94026.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EXOSC1 PF10447.9 KRH94033.1 - 0.024 15.2 0.0 8.9 7.0 0.0 2.6 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 DNA_primase_S PF01896.19 KRH94035.1 - 4.7e-17 62.6 3.1 2.2e-10 40.9 0.2 2.6 2 1 1 3 3 3 2 DNA primase small subunit DUF5342 PF17277.2 KRH94035.1 - 0.065 13.6 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5342) Per1 PF04080.13 KRH94036.1 - 8.8e-13 48.6 7.3 5.3e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 Per1-like family Ribosomal_S19 PF00203.21 KRH94038.1 - 4.4e-16 58.5 0.1 6.1e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3551 PF12071.8 KRH94038.1 - 0.038 14.0 0.6 0.09 12.8 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3551) Adap_comp_sub PF00928.21 KRH94039.1 - 7.4e-07 28.8 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Self-incomp_S1 PF05938.11 KRH94039.1 - 0.057 14.0 1.3 2.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Plant self-incompatibility protein S1 BRCC36_C PF18110.1 KRH94040.1 - 0.0042 17.2 19.1 3.7 7.8 0.4 4.5 1 1 3 4 4 4 4 BRCC36 C-terminal helical domain BCL9 PF11502.8 KRH94040.1 - 0.013 15.2 5.3 54 3.7 0.1 4.3 4 0 0 4 4 4 0 B-cell lymphoma 9 protein DUF3377 PF11857.8 KRH94040.1 - 0.027 14.4 0.5 0.17 11.8 0.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ccdc124 PF06244.12 KRH94040.1 - 0.03 14.9 23.4 5.3 7.6 0.9 4.6 1 1 4 5 5 5 0 Coiled-coil domain-containing protein 124 /Oxs1 LMBR1 PF04791.16 KRH94040.1 - 0.57 9.0 14.2 0.68 8.8 14.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4412 PF14371.6 KRH94040.1 - 2.6 7.8 12.9 4.6 7.0 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4412) DDE_Tnp_IS1595 PF12762.7 KRH94042.1 - 2.4e-23 82.8 0.2 3e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain Corona_RPol_N PF06478.13 KRH94042.1 - 0.008 15.2 0.2 0.0099 14.9 0.2 1.1 1 0 0 1 1 1 1 Coronavirus RPol N-terminus DUF2179 PF10035.9 KRH94042.1 - 1.4 8.7 3.6 0.53 10.1 0.5 1.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) PUF PF00806.19 KRH94043.1 - 0.0074 15.9 0.2 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat zf-C4_Topoisom PF01396.19 KRH94043.1 - 0.0096 15.7 4.4 0.026 14.3 4.4 1.8 1 1 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Herpes_TAF50 PF03326.13 KRH94044.1 - 0.0097 14.6 0.1 0.011 14.5 0.1 1.0 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) DDE_Tnp_IS1595 PF12762.7 KRH94045.1 - 0.052 13.6 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain rve PF00665.26 KRH94047.1 - 2.3e-12 47.1 0.0 5.8e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH94047.1 - 3.6e-06 27.0 1.1 1.7e-05 24.8 1.1 2.2 1 1 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_4 PF13359.6 KRH94048.1 - 6.9e-17 61.6 0.9 1.1e-16 60.9 0.1 1.8 2 1 1 3 3 3 1 DDE superfamily endonuclease Plant_tran PF04827.14 KRH94048.1 - 8.2e-05 22.3 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein aGPT-Pplase1 PF18723.1 KRH94048.1 - 0.00018 21.1 0.5 0.0003 20.3 0.5 1.3 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 DDE_Tnp_1 PF01609.21 KRH94048.1 - 0.00048 19.8 0.0 0.013 15.2 0.0 2.4 2 1 0 2 2 2 1 Transposase DDE domain SpoIIID PF12116.8 KRH94048.1 - 0.0016 18.5 0.1 0.0038 17.3 0.1 1.6 1 0 0 1 1 1 1 Stage III sporulation protein D Trp_repressor PF01371.19 KRH94048.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Trp repressor protein VHP PF02209.19 KRH94048.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.8 3 0 0 3 3 3 0 Villin headpiece domain Myb_DNA-bind_4 PF13837.6 KRH94049.1 - 0.0018 18.6 5.9 0.0018 18.6 5.9 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KRH94049.1 - 0.0052 17.1 0.4 0.0052 17.1 0.4 2.7 2 2 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PNPase PF03726.14 KRH94049.1 - 0.014 15.9 4.6 0.014 15.8 2.4 2.2 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain WDCP PF15390.6 KRH94049.1 - 0.5 8.7 10.6 0.54 8.6 10.6 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family IBP39 PF11422.8 KRH94050.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Initiator binding protein 39 kDa SAVED PF18145.1 KRH94051.1 - 0.17 11.7 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Ribosomal_L30 PF00327.20 KRH94053.1 - 5.2e-10 39.1 1.1 1.1e-09 38.0 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MitMem_reg PF13012.6 KRH94053.1 - 1.3 9.5 6.5 8.7 6.8 5.4 2.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DnaJ PF00226.31 KRH94055.1 - 2.2e-11 43.7 0.5 2.2e-11 43.7 0.5 2.5 3 0 0 3 3 3 1 DnaJ domain TPR_19 PF14559.6 KRH94055.1 - 0.00017 22.1 0.0 0.74 10.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat BSD PF03909.17 KRH94055.1 - 0.0035 17.3 0.8 0.72 9.9 0.0 3.4 3 0 0 3 3 3 1 BSD domain Pex14_N PF04695.13 KRH94055.1 - 0.057 14.1 6.5 0.11 13.1 6.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 KRH94055.1 - 9.5 4.9 7.0 13 4.5 7.0 1.3 1 0 0 1 1 1 0 Presenilin AT_hook PF02178.19 KRH94056.1 - 0.058 13.3 2.9 0.17 11.9 2.9 1.8 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.27 KRH94057.1 - 4.4e-25 88.8 0.1 8.5e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KRH94057.1 - 5.4e-09 35.8 0.1 9.9e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KRH94057.1 - 1.8e-05 25.1 0.0 5.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH94057.1 - 0.0014 18.6 1.9 0.0036 17.3 0.0 2.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KRH94057.1 - 0.0017 18.7 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KRH94057.1 - 0.0024 17.0 0.3 0.0048 16.0 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KRH94057.1 - 0.0036 17.0 0.4 0.0094 15.7 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KRH94057.1 - 0.0083 16.7 1.4 0.016 15.7 0.3 2.3 2 1 0 2 2 1 1 AAA domain AAA_21 PF13304.6 KRH94057.1 - 0.01 15.7 0.8 1.3 8.8 0.2 2.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KRH94057.1 - 0.013 15.4 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KRH94057.1 - 0.014 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 KRH94057.1 - 0.016 15.3 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Dynamin family SbcCD_C PF13558.6 KRH94057.1 - 0.05 13.8 0.0 0.7 10.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KRH94057.1 - 0.054 13.2 0.2 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KRH94057.1 - 0.06 13.4 0.2 0.2 11.8 0.2 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KRH94057.1 - 0.099 13.1 0.9 1.1 9.7 0.9 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KRH94057.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 KRH94057.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KRH94057.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 KRH94057.1 - 0.15 11.4 26.8 0.019 14.4 22.0 1.9 2 1 0 2 2 2 0 ABC-2 type transporter AAA_19 PF13245.6 KRH94057.1 - 0.2 12.0 1.9 1.1 9.6 1.9 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 KRH94057.1 - 2.9 7.9 6.3 6.2 6.8 0.4 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain Herpes_UL6 PF01763.16 KRH94058.1 - 0.017 13.7 2.8 0.02 13.5 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CobU PF02283.16 KRH94058.1 - 0.051 13.1 0.4 0.069 12.7 0.4 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SUA5 PF03481.13 KRH94058.1 - 0.083 13.5 0.4 0.11 13.0 0.4 1.2 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding TAFII55_N PF04658.13 KRH94059.1 - 1.1e-21 77.3 0.6 1.1e-21 77.3 0.6 2.8 2 1 1 3 3 3 1 TAFII55 protein conserved region DUF3783 PF12646.7 KRH94059.1 - 0.1 12.6 1.7 0.89 9.6 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3783) DUF1451 PF07295.11 KRH94059.1 - 0.12 12.4 5.2 0.3 11.1 5.2 1.7 1 1 0 1 1 1 0 Zinc-ribbon containing domain STAT_int PF02865.17 KRH94059.1 - 0.47 10.9 7.4 0.13 12.7 2.3 2.3 1 1 2 3 3 3 0 STAT protein, protein interaction domain Collagen PF01391.18 KRH94061.1 - 9e-05 22.2 6.1 9e-05 22.2 6.1 2.2 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) HA2 PF04408.23 KRH94062.1 - 1.9e-16 60.3 0.2 5.4e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KRH94062.1 - 2.7e-16 59.9 1.1 2.7e-16 59.9 1.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KRH94062.1 - 3.8e-11 43.2 0.1 1.4e-10 41.4 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KRH94062.1 - 0.00033 20.5 0.1 0.0034 17.2 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KRH94062.1 - 0.00038 20.5 0.4 0.00038 20.5 0.4 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF3914 PF13053.6 KRH94062.1 - 0.00075 19.8 2.3 0.36 11.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3914) AAA_30 PF13604.6 KRH94062.1 - 0.0018 18.1 0.0 0.051 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KRH94062.1 - 0.002 18.2 0.4 0.013 15.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KRH94062.1 - 0.0068 16.3 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 KRH94062.1 - 0.054 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KRH94062.1 - 0.57 10.1 2.9 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_23 PF13476.6 KRH94062.1 - 3.8 8.0 12.4 0.46 11.0 4.1 3.0 2 1 0 2 2 2 0 AAA domain Homeobox_KN PF05920.11 KRH94064.1 - 1.6e-17 63.1 0.5 3.7e-17 61.9 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KRH94064.1 - 4.8e-08 32.7 0.9 4.8e-08 32.7 0.9 2.5 2 1 0 2 2 2 1 Homeodomain AATF-Che1 PF13339.6 KRH94064.1 - 0.0039 17.9 2.1 0.0039 17.9 2.1 1.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor E2F_CC-MB PF16421.5 KRH94064.1 - 0.29 11.5 4.0 0.53 10.7 3.9 1.6 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain Homeodomain PF00046.29 KRH94065.1 - 5.8e-15 54.9 0.4 2e-14 53.2 0.4 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH94065.1 - 2.3e-11 43.4 0.9 5.5e-11 42.2 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain DUF2963 PF11178.8 KRH94065.1 - 0.0019 17.9 0.8 0.0034 17.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2963) PIN_8 PF18476.1 KRH94065.1 - 0.014 15.2 0.6 0.02 14.8 0.6 1.2 1 0 0 1 1 1 0 PIN like domain Homez PF11569.8 KRH94065.1 - 0.18 11.3 0.0 0.46 10.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DDE_3 PF13358.6 KRH94066.1 - 2.3e-06 27.4 0.3 4.2e-06 26.6 0.2 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Autophagy_C PF10381.9 KRH94066.1 - 0.62 9.6 4.7 1.1 8.8 4.7 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Ribosomal_L29e PF01779.17 KRH94068.1 - 1.5e-12 47.6 4.7 1.5e-12 47.6 4.7 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family MRP-S26 PF14943.6 KRH94068.1 - 0.051 13.5 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 RNA_pol_I_A49 PF06870.12 KRH94070.1 - 4.4e-13 48.9 3.2 2.6e-07 29.9 0.3 2.3 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor Ribosomal_S27e PF01667.17 KRH94071.1 - 2.1e-15 56.1 0.9 2.7e-15 55.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 SIR2 PF02146.17 KRH94071.1 - 0.047 13.6 0.3 0.047 13.6 0.3 1.1 1 0 0 1 1 1 0 Sir2 family DS PF01916.17 KRH94074.1 - 9.3e-32 110.4 2.9 5.1e-28 98.2 2.9 3.2 1 1 0 1 1 1 1 Deoxyhypusine synthase RNase_HII PF01351.18 KRH94075.1 - 1.6e-21 77.1 0.9 1.2e-10 41.5 0.1 2.9 2 1 1 3 3 3 2 Ribonuclease HII Spore_YpjB PF09577.10 KRH94075.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) DUF5392 PF17370.2 KRH94075.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5392) PFK PF00365.20 KRH94076.1 - 2.2e-62 210.9 0.6 9.9e-62 208.8 0.6 2.0 1 1 0 1 1 1 1 Phosphofructokinase Ribosomal_S20p PF01649.18 KRH94076.1 - 0.16 12.7 2.9 16 6.3 0.2 3.8 4 0 0 4 4 4 0 Ribosomal protein S20 Ezh2_MCSS PF18600.1 KRH94077.1 - 0.035 13.7 1.8 0.079 12.6 1.8 1.6 1 0 0 1 1 1 0 MCSS domain HLH PF00010.26 KRH94079.1 - 0.00014 21.7 0.7 0.00038 20.4 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S14 PF00253.21 KRH94080.1 - 5.5e-09 35.7 4.8 6.7e-09 35.4 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Phage_TTP_11 PF16460.5 KRH94080.1 - 0.044 13.6 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like Ribosomal_S7 PF00177.21 KRH94081.1 - 2.2e-32 111.8 0.2 2.7e-32 111.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3113 PF11310.8 KRH94082.1 - 1.1 9.2 16.2 37 4.3 0.1 6.2 2 2 2 4 4 4 0 Protein of unknown function (DUF3113) Pentapeptide_4 PF13599.6 KRH94082.1 - 4.2 7.6 36.4 32 4.8 12.3 3.2 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) POC1 PF10450.9 KRH94083.1 - 0.0046 16.0 0.1 0.0046 16.0 0.1 1.1 1 0 0 1 1 1 1 POC1 chaperone Helicase_RecD PF05127.14 KRH94084.1 - 3.2e-29 102.0 2.3 1.2e-22 80.6 0.1 2.8 1 1 1 2 2 2 2 Helicase DUF1726 PF08351.11 KRH94084.1 - 1.3e-10 41.0 0.2 1.2e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KRH94084.1 - 0.02 14.6 0.0 0.28 10.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain YscO PF07321.12 KRH94085.1 - 0.0063 16.5 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO Sds3 PF08598.11 KRH94085.1 - 0.009 16.0 1.8 0.068 13.2 0.4 2.2 2 0 0 2 2 2 1 Sds3-like KELK PF15796.5 KRH94085.1 - 0.042 14.3 2.7 0.08 13.4 1.8 1.9 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Csm1_N PF18504.1 KRH94085.1 - 0.23 11.8 5.5 0.26 11.6 0.5 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF3560 PF12083.8 KRH94087.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) HEPN_RiboL-PSP PF18735.1 KRH94088.1 - 0.076 12.9 2.1 0.11 12.4 2.1 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN Ras PF00071.22 KRH94089.1 - 3.3e-51 173.1 0.0 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH94089.1 - 7.7e-25 87.4 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH94089.1 - 7.2e-08 32.1 0.0 1e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KRH94089.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ribosomal_L30_N PF08079.12 KRH94089.1 - 0.004 17.4 0.4 0.0067 16.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain G-alpha PF00503.20 KRH94089.1 - 0.065 12.4 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 KRH94089.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KRH94089.1 - 0.19 11.2 0.3 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pyrophosphatase PF00719.19 KRH94090.1 - 5.9e-49 165.9 0.8 9e-49 165.3 0.8 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase RNA_pol_Rpb6 PF01192.22 KRH94091.1 - 1.4e-10 40.9 0.1 2.2e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Tat PF00539.18 KRH94092.1 - 1.5 9.0 5.7 3.5 7.8 5.7 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) RCC1 PF00415.18 KRH94093.1 - 6.5e-28 97.1 5.2 6.9e-07 29.8 0.0 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KRH94093.1 - 2.4e-19 68.6 9.8 4.4e-07 29.5 0.0 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF2433 PF10360.9 KRH94093.1 - 0.078 13.1 1.0 0.17 12.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Ribosomal_L26 PF16906.5 KRH94094.1 - 6.2e-23 81.1 1.7 1.5e-22 79.8 1.7 1.6 1 1 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KRH94094.1 - 4.1e-05 23.4 0.6 9.5e-05 22.2 0.6 1.6 1 0 0 1 1 1 1 KOW motif DUF4294 PF14127.6 KRH94094.1 - 0.3 11.0 2.1 1.7 8.5 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) ECR1_N PF14382.6 KRH94097.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Flt3_lig PF02947.14 KRH94098.1 - 0.058 13.6 0.3 0.058 13.6 0.3 1.0 1 0 0 1 1 1 0 flt3 ligand SPC25 PF06703.11 KRH94100.1 - 1.2e-24 86.9 4.1 1.2e-24 86.9 4.1 1.4 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1385 PF07136.11 KRH94100.1 - 0.0067 15.8 1.6 0.01 15.1 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) MgtE PF01769.16 KRH94100.1 - 0.055 13.9 1.1 0.082 13.3 1.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter Hexapep PF00132.24 KRH94101.1 - 5.3e-06 25.9 0.1 0.047 13.4 0.0 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DDE_3 PF13358.6 KRH94103.1 - 1.2e-08 34.9 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rRNA_methylase PF06962.12 KRH94103.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.5 1 1 0 1 1 1 0 Putative rRNA methylase Retrotrans_gag PF03732.17 KRH94107.1 - 0.033 14.5 0.1 0.039 14.2 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein BicD PF09730.9 KRH94108.1 - 0.011 14.2 0.0 0.011 14.2 0.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D RVT_1 PF00078.27 KRH94109.1 - 1.2e-12 47.8 0.0 1.6e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4939 PF16297.5 KRH94111.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KRH94111.1 - 0.12 12.6 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein PocR PF10114.9 KRH94114.1 - 0.015 15.1 0.4 0.015 15.1 0.4 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR Chlor_dismutase PF06778.12 KRH94114.1 - 0.021 14.4 0.5 0.023 14.3 0.5 1.1 1 0 0 1 1 1 0 Chlorite dismutase UPF0182 PF03699.13 KRH94114.1 - 0.082 11.0 0.1 0.09 10.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) gag-asp_proteas PF13975.6 KRH94115.1 - 2.3e-08 34.5 0.1 3.7e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94115.1 - 1.2e-07 32.2 0.1 2.2e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 KRH94115.1 - 4.2e-06 26.5 0.1 8.6e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 KRH94115.1 - 2.7e-05 24.4 0.1 7.7e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.11 KRH94115.1 - 5.9e-05 22.9 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2E PF12382.8 KRH94115.1 - 0.019 15.0 0.1 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon peptidase Asp_protease PF09668.10 KRH94115.1 - 0.024 14.4 0.1 0.089 12.6 0.1 2.0 1 1 0 1 1 1 0 Aspartyl protease Methyltransf_12 PF08242.12 KRH94115.1 - 0.1 13.3 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RT_RNaseH_2 PF17919.1 KRH94116.1 - 1.2e-12 47.7 0.1 7.7e-12 45.1 0.1 2.0 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94116.1 - 0.00016 21.9 0.0 0.00078 19.7 0.0 2.1 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 KRH94116.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain rve PF00665.26 KRH94117.1 - 6.7e-17 61.8 0.0 1.3e-16 60.9 0.0 1.4 2 0 0 2 2 2 1 Integrase core domain MLVIN_C PF18697.1 KRH94117.1 - 0.0012 18.9 0.2 0.004 17.2 0.0 1.9 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Proteasome PF00227.26 KRH94118.1 - 3.2e-46 157.2 0.3 4.2e-46 156.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF4950 PF16308.5 KRH94118.1 - 0.075 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) Mlo PF03094.15 KRH94121.1 - 8.2 4.7 18.0 1.3 7.3 4.9 2.1 1 1 1 2 2 2 0 Mlo family Got1 PF04178.12 KRH94122.1 - 3.1e-21 75.9 21.4 5e-21 75.2 21.4 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family CBFD_NFYB_HMF PF00808.23 KRH94123.1 - 1.2e-18 67.1 0.9 1.8e-18 66.6 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRH94123.1 - 6.1e-10 39.6 0.6 7.4e-10 39.3 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KRH94123.1 - 0.045 14.1 0.4 0.083 13.2 0.4 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TAFII28 PF04719.14 KRH94123.1 - 0.046 13.8 0.2 0.067 13.3 0.2 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PI3_PI4_kinase PF00454.27 KRH94124.1 - 3e-23 82.9 0.1 1e-20 74.6 0.1 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1517 PF07466.11 KRH94125.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) UDPGP PF01704.18 KRH94126.1 - 5.8e-173 575.3 1.3 6.9e-173 575.0 1.3 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ATP-synt_F PF01990.17 KRH94127.1 - 2.1e-17 63.2 0.3 2.4e-17 63.0 0.3 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Ribosomal_S9 PF00380.19 KRH94128.1 - 6.2e-23 81.6 0.2 7.1e-23 81.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 KRH94129.1 - 2e-41 141.8 7.0 2.5e-41 141.5 7.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L24e PF01246.20 KRH94130.1 - 4.6e-27 94.0 6.0 4.6e-27 94.0 6.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DnaB PF00772.21 KRH94130.1 - 0.00056 20.0 0.6 0.00076 19.5 0.6 1.3 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain PseudoU_synth_1 PF01416.20 KRH94130.1 - 0.068 13.6 0.2 0.098 13.1 0.2 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase PIP5K PF01504.18 KRH94131.1 - 8.3e-54 182.6 13.5 1.6e-53 181.7 13.5 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PDDEXK_7 PF04411.12 KRH94131.1 - 0.056 13.4 1.9 1.5 8.7 0.4 2.2 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily PCI PF01399.27 KRH94132.1 - 0.03 14.8 5.2 0.04 14.4 1.1 3.0 2 2 0 2 2 2 0 PCI domain DNA_pol_alpha_N PF12254.8 KRH94132.1 - 0.045 13.8 0.3 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal NAD_binding_5 PF07994.12 KRH94132.1 - 0.049 13.0 0.8 0.075 12.4 0.8 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Septin PF00735.18 KRH94134.1 - 1.2e-52 179.0 12.4 7.7e-43 146.8 8.5 3.0 1 1 1 2 2 2 2 Septin AAA_14 PF13173.6 KRH94134.1 - 0.00038 20.5 0.3 0.00038 20.5 0.3 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KRH94134.1 - 0.00072 19.0 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.29 KRH94134.1 - 0.01 16.3 0.3 0.026 15.0 0.3 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KRH94134.1 - 0.03 13.4 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KRH94134.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 KRH94134.1 - 0.046 13.9 0.6 1.7 8.9 0.6 2.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KRH94134.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KRH94134.1 - 0.075 13.5 1.3 0.21 12.1 1.2 1.9 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KRH94134.1 - 0.096 12.7 1.1 0.19 11.8 1.1 1.6 1 1 0 1 1 1 0 Dynamin family Rad17 PF03215.15 KRH94134.1 - 0.11 12.4 2.4 3.6 7.5 1.3 2.9 2 1 1 3 3 3 0 Rad17 P-loop domain AAA_33 PF13671.6 KRH94134.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 KRH94135.1 - 1.4e-132 442.8 0.7 1.7e-132 442.6 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KRH94135.1 - 0.25 11.4 1.0 43 4.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Zip PF02535.22 KRH94136.1 - 7.4e-24 84.6 20.7 4.9e-21 75.3 4.7 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4940 PF16298.5 KRH94136.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4940) Ribonuclease_3 PF00636.26 KRH94138.1 - 1e-27 96.8 0.1 2.5e-14 53.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KRH94138.1 - 6.7e-22 78.0 0.5 5.9e-09 36.2 0.0 4.1 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KRH94138.1 - 1.8e-05 24.8 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Proteasome PF00227.26 KRH94139.1 - 1.9e-29 102.5 0.0 2.5e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ETRAMP PF09716.10 KRH94140.1 - 9.7e-05 22.4 4.1 0.00038 20.4 4.1 1.9 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) ApoC-I PF04691.12 KRH94140.1 - 0.00019 21.3 1.4 0.0041 17.0 0.2 2.6 1 1 1 2 2 2 1 Apolipoprotein C-I (ApoC-1) phage_tail_N PF08400.10 KRH94140.1 - 0.049 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Phasin PF05597.11 KRH94140.1 - 0.051 13.6 2.4 0.096 12.7 2.4 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3810 PF12725.7 KRH94140.1 - 0.15 11.4 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF883 PF05957.13 KRH94140.1 - 0.17 12.5 0.5 4.4 8.0 0.4 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KRH94140.1 - 0.25 11.9 5.2 3.2 8.3 5.2 2.1 1 1 0 1 1 1 0 YtxH-like protein Mt_ATP-synt_B PF05405.14 KRH94140.1 - 0.86 9.2 3.8 1.8 8.2 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_B PF00430.18 KRH94140.1 - 2.5 8.2 5.7 0.17 11.9 1.2 1.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF1456 PF07308.13 KRH94141.1 - 0.098 13.0 1.9 0.3 11.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) MAP17 PF15807.5 KRH94141.1 - 0.12 12.6 2.3 0.18 12.0 2.3 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 KRH94141.1 - 0.13 11.9 1.5 0.21 11.2 1.5 1.5 1 1 0 1 1 1 0 FAM176 family COX16 PF14138.6 KRH94141.1 - 0.35 11.4 9.6 0.23 12.0 6.6 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Zip PF02535.22 KRH94141.1 - 0.38 9.9 0.9 0.37 9.9 0.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter ETRAMP PF09716.10 KRH94141.1 - 0.76 9.9 10.1 3 8.0 10.1 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DnaJ PF00226.31 KRH94142.1 - 1.4e-05 25.2 1.3 5.2e-05 23.3 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain PhdYeFM_antitox PF02604.19 KRH94142.1 - 0.034 13.9 0.3 1.5 8.7 0.1 2.5 1 1 1 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Myb_DNA-bind_4 PF13837.6 KRH94142.1 - 0.068 13.6 0.4 0.068 13.6 0.4 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain RNA_pol_Rpb5_C PF01191.19 KRH94143.1 - 6.3e-25 86.9 0.6 1.2e-24 85.9 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KRH94143.1 - 5.2e-15 55.8 0.9 1.1e-14 54.7 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Phage_holin_2_1 PF04971.12 KRH94145.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage P21 holin S MLANA PF14991.6 KRH94145.1 - 0.14 12.4 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Ribosomal_S13 PF00416.22 KRH94146.1 - 5.8e-31 107.5 1.5 6.7e-31 107.3 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 SBDS PF01172.18 KRH94147.1 - 3.1e-10 40.0 0.6 1.8e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zinc_ribbon_15 PF17032.5 KRH94149.1 - 2.5e-13 50.6 15.2 2.5e-13 50.6 15.2 1.6 2 0 0 2 2 2 1 zinc-ribbon family DZR PF12773.7 KRH94149.1 - 4e-06 26.7 10.0 0.0006 19.8 0.9 2.8 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 KRH94149.1 - 0.0029 17.3 2.6 0.0029 17.3 2.6 3.7 3 1 1 4 4 4 1 zinc-ribbon domain RecR PF02132.15 KRH94149.1 - 0.0077 15.8 6.0 0.17 11.5 0.8 3.4 3 0 0 3 3 3 1 RecR protein Rad50_zn_hook PF04423.14 KRH94149.1 - 0.0088 15.9 0.8 0.45 10.4 0.1 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-NADH-PPase PF09297.11 KRH94149.1 - 0.016 14.9 9.1 0.028 14.1 0.1 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zinc-ribbons_6 PF07191.12 KRH94149.1 - 0.021 14.8 2.7 0.021 14.8 2.7 2.5 2 1 0 2 2 2 0 zinc-ribbons Cript PF10235.9 KRH94149.1 - 0.025 15.1 4.8 0.025 15.1 4.8 2.4 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-ribbon_3 PF13248.6 KRH94149.1 - 0.16 11.4 14.6 3.5 7.2 4.0 3.7 2 1 1 3 3 3 0 zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 KRH94149.1 - 0.25 12.1 4.3 7 7.5 0.1 3.4 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF2225 PF09986.9 KRH94149.1 - 0.35 10.6 9.3 1.8 8.3 2.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Prok-RING_4 PF14447.6 KRH94149.1 - 0.58 10.1 16.1 0.56 10.1 2.0 3.5 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 KRH94149.1 - 0.87 10.1 9.7 1.9 9.0 0.3 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain TF_Zn_Ribbon PF08271.12 KRH94149.1 - 1 8.9 14.6 0.56 9.8 2.7 3.6 2 1 1 3 3 3 0 TFIIB zinc-binding DNA_ligase_ZBD PF03119.16 KRH94149.1 - 1 9.5 11.4 2 8.5 0.1 3.3 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C3HC4_3 PF13920.6 KRH94149.1 - 1.2 9.0 18.8 2 8.3 3.4 3.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.6 KRH94149.1 - 1.9 7.9 14.1 7.2 6.0 0.2 3.7 3 1 0 3 3 3 0 Transcription factor zinc-finger zf-C2H2_9 PF16293.5 KRH94149.1 - 2.6 8.0 9.6 14 5.6 0.3 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KRH94149.1 - 3.2 8.1 15.4 0.83 10.0 2.5 3.6 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PIH1 PF08190.12 KRH94150.1 - 0.052 13.0 0.1 0.057 12.9 0.1 1.0 1 0 0 1 1 1 0 PIH1 N-terminal domain DZR PF12773.7 KRH94151.1 - 7.9e-06 25.8 4.8 7.9e-06 25.8 4.8 2.5 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KRH94151.1 - 1.7e-05 25.5 13.3 5e-05 24.0 13.3 1.8 1 1 0 1 1 1 1 zinc-ribbon family zf-ribbon_3 PF13248.6 KRH94151.1 - 0.019 14.3 1.1 0.019 14.3 1.1 3.5 4 1 1 5 5 5 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KRH94151.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.8 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KRH94151.1 - 0.11 12.5 12.3 0.29 11.1 0.0 3.5 3 1 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KRH94151.1 - 0.28 11.0 0.2 0.28 11.0 0.2 3.6 2 1 2 4 4 4 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KRH94151.1 - 6.7 6.7 12.7 0.14 12.0 1.6 3.0 2 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Retrotrans_gag PF03732.17 KRH94153.1 - 0.011 16.0 0.4 1.1 9.6 0.1 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein Adenylsucc_synt PF00709.21 KRH94153.1 - 0.12 11.3 0.3 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase rve PF00665.26 KRH94154.1 - 3.8e-14 52.9 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH94154.1 - 0.0043 16.8 0.1 0.0091 15.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain PTPS PF01242.19 KRH94154.1 - 0.045 13.7 0.1 0.79 9.7 0.0 2.2 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Cytidylate_kin PF02224.18 KRH94154.1 - 0.071 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Cytidylate kinase Aminotran_5 PF00266.19 KRH94155.1 - 1.6e-85 287.3 0.0 1.9e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 KRH94155.1 - 1.8e-06 26.9 0.1 3.9e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KRH94155.1 - 5.4e-06 25.9 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KRH94155.1 - 0.00037 19.9 0.1 0.00054 19.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3449 PF11931.8 KRH94157.1 - 5.9e-10 39.2 2.7 5.9e-10 39.2 2.7 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KRH94157.1 - 0.022 15.3 2.5 0.022 15.3 2.5 3.1 3 1 1 4 4 4 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 OrsD PF12013.8 KRH94157.1 - 0.065 13.7 0.8 0.2 12.1 0.1 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KRH94157.1 - 0.12 12.7 18.4 0.1 13.0 2.4 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 KRH94157.1 - 0.85 10.4 4.0 0.4 11.5 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon family zf-BED PF02892.15 KRH94157.1 - 3.4 7.8 8.5 5.1 7.2 0.3 2.7 2 0 0 2 2 2 0 BED zinc finger RVT_1 PF00078.27 KRH94160.1 - 0.002 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SOG2 PF10428.9 KRH94163.1 - 0.069 12.3 10.9 0.083 12.1 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KRH94163.1 - 0.085 11.5 7.2 0.097 11.3 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 KRH94163.1 - 0.91 9.5 5.1 1.2 9.1 5.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KRH94163.1 - 2 7.1 11.9 2.6 6.7 11.9 1.2 1 0 0 1 1 1 0 Presenilin PARM PF17061.5 KRH94163.1 - 3.6 7.6 16.6 5.2 7.1 16.6 1.1 1 0 0 1 1 1 0 PARM DUF963 PF06131.11 KRH94163.1 - 3.6 7.1 10.6 0.62 9.5 2.0 2.9 1 1 1 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Lin-8 PF03353.15 KRH94163.1 - 8.6 5.8 15.6 13 5.3 15.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 KRH94163.1 - 9.1 4.7 15.2 9.7 4.6 15.2 1.1 1 0 0 1 1 1 0 Macoilin family NUMOD1 PF07453.13 KRH94166.1 - 0.068 13.5 0.3 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 NUMOD1 domain Ribosomal_L21e PF01157.18 KRH94170.1 - 5.3e-36 122.5 4.4 8.7e-36 121.8 4.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e S4 PF01479.25 KRH94172.1 - 2.7e-09 36.6 0.4 5.4e-09 35.6 0.4 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KRH94172.1 - 0.0013 19.6 0.2 0.0018 19.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF826 PF05696.11 KRH94172.1 - 0.049 13.7 0.5 0.085 12.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Suv3_N PF18114.1 KRH94173.1 - 0.19 11.9 4.5 0.17 12.0 1.8 2.2 1 1 1 2 2 2 0 Suv3 helical N-terminal domain ZapB PF06005.12 KRH94173.1 - 1.7 9.1 12.9 0.85 10.1 2.3 3.1 1 1 1 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 KRH94173.1 - 2.2 8.5 16.0 5 7.4 1.4 3.3 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 KRH94173.1 - 4.6 7.1 13.5 1.9 8.3 2.0 3.4 1 1 2 3 3 3 0 Septum formation initiator Laminin_II PF06009.12 KRH94173.1 - 8.6 6.4 17.4 1.2 9.2 6.5 3.0 2 1 1 3 3 3 0 Laminin Domain II ACP_PD PF04336.12 KRH94174.1 - 0.11 12.9 0.3 0.91 10.0 0.1 2.5 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase RRP36 PF06102.12 KRH94174.1 - 0.56 10.2 11.7 0.089 12.8 5.0 2.7 3 0 0 3 3 3 0 rRNA biogenesis protein RRP36 TMEM51 PF15345.6 KRH94174.1 - 2.7 7.8 9.2 0.27 11.0 2.5 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 RapH_N PF18801.1 KRH94174.1 - 4.2 7.5 10.7 0.083 13.0 2.6 2.5 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal DUF3484 PF11983.8 KRH94175.1 - 0.0058 17.7 0.7 0.0093 17.1 0.1 1.6 2 0 0 2 2 2 1 Membrane-attachment and polymerisation-promoting switch Fungal_trans PF04082.18 KRH94175.1 - 0.0082 15.2 1.2 0.0095 15.0 0.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1117 PF06547.12 KRH94175.1 - 0.086 13.4 0.4 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) CBFB_NFYA PF02045.15 KRH94176.1 - 2.3e-20 72.9 1.7 6.3e-20 71.6 1.7 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B WD40 PF00400.32 KRH94177.1 - 7.1e-08 33.0 7.1 0.017 16.0 0.0 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat MbeD_MobD PF04899.12 KRH94178.1 - 8.7e-05 22.6 0.1 0.38 10.9 0.1 2.6 1 1 1 2 2 2 2 MbeD/MobD like DUF16 PF01519.16 KRH94178.1 - 0.00045 20.7 7.2 0.0082 16.6 7.2 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF16 CENP-H PF05837.12 KRH94178.1 - 0.0021 18.4 6.8 0.019 15.4 6.8 1.9 1 1 0 1 1 1 1 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 KRH94178.1 - 0.0023 17.9 25.2 0.036 14.0 15.7 2.2 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 KRH94178.1 - 0.0043 16.9 5.8 0.0054 16.6 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) SlyX PF04102.12 KRH94178.1 - 0.0072 16.9 2.9 0.035 14.7 2.9 1.9 1 1 0 1 1 1 1 SlyX DivIC PF04977.15 KRH94178.1 - 0.015 15.0 11.3 0.077 12.8 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator LPP PF04728.13 KRH94178.1 - 0.017 15.5 9.5 1.8 9.0 0.6 3.0 1 1 2 3 3 3 0 Lipoprotein leucine-zipper Nup54 PF13874.6 KRH94178.1 - 0.019 15.1 4.4 0.1 12.7 1.9 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2935 PF11155.8 KRH94178.1 - 0.02 15.3 6.3 0.78 10.1 5.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ATG16 PF08614.11 KRH94178.1 - 0.022 15.0 2.5 0.031 14.5 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) COG5 PF10392.9 KRH94178.1 - 0.025 14.7 7.4 0.033 14.4 7.4 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 KRH94178.1 - 0.025 14.6 8.2 0.03 14.3 8.2 1.1 1 0 0 1 1 1 0 Laminin Domain II BRE1 PF08647.11 KRH94178.1 - 0.035 14.2 11.6 0.05 13.7 11.6 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase NCD2 PF04905.13 KRH94178.1 - 0.036 14.1 3.0 0.046 13.7 2.3 1.5 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) DUF1664 PF07889.12 KRH94178.1 - 0.039 14.0 4.7 0.048 13.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4763 PF15960.5 KRH94178.1 - 0.041 13.2 10.5 0.021 14.1 4.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF2290 PF10053.9 KRH94178.1 - 0.062 12.8 1.2 0.36 10.3 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2290) PhoU PF01895.19 KRH94178.1 - 0.11 13.0 5.9 2.7 8.5 5.9 2.2 1 1 0 1 1 1 0 PhoU domain OEP PF02321.18 KRH94178.1 - 0.12 12.2 5.4 2.8 7.7 0.5 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein Vps51 PF08700.11 KRH94178.1 - 0.13 12.4 9.5 1.1 9.4 2.1 2.2 1 1 1 2 2 2 0 Vps51/Vps67 PMC2NT PF08066.12 KRH94178.1 - 0.15 12.7 4.8 12 6.7 1.3 2.7 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Atg14 PF10186.9 KRH94178.1 - 0.2 10.7 8.1 0.25 10.4 8.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PDZ_2 PF13180.6 KRH94178.1 - 0.2 12.0 1.4 6.2 7.2 1.3 2.2 1 1 0 1 1 1 0 PDZ domain GrpE PF01025.19 KRH94178.1 - 0.28 10.8 7.1 1.1 8.8 7.3 1.7 1 1 0 1 1 1 0 GrpE DUF4200 PF13863.6 KRH94178.1 - 0.32 11.4 14.2 3.2 8.2 14.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ACCA PF03255.14 KRH94178.1 - 0.42 10.5 4.5 2.4 8.0 4.5 1.9 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BLOC1_2 PF10046.9 KRH94178.1 - 0.55 10.6 11.5 0.89 9.9 11.2 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 KRH94178.1 - 0.62 8.6 10.2 0.71 8.4 10.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med3 PF11593.8 KRH94178.1 - 0.7 9.0 7.0 32 3.5 7.0 2.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Prefoldin PF02996.17 KRH94178.1 - 0.72 9.8 13.2 1.2 9.0 3.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Uds1 PF15456.6 KRH94178.1 - 1.1 9.5 6.7 6.6 6.9 3.9 2.0 1 1 1 2 2 2 0 Up-regulated During Septation DASH_Dad4 PF08650.10 KRH94178.1 - 1.1 9.3 9.1 14 5.7 0.7 3.2 1 1 1 2 2 2 0 DASH complex subunit Dad4 Fib_alpha PF08702.10 KRH94178.1 - 1.4 9.1 13.3 0.88 9.7 7.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 KRH94178.1 - 1.5 9.3 11.2 5.7 7.4 0.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 KRH94178.1 - 1.7 9.2 15.6 16 6.1 14.1 2.2 1 1 0 1 1 1 0 Cell division protein ZapB MIP-T3_C PF17749.1 KRH94178.1 - 2.1 8.3 13.9 2.4 8.1 7.6 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region GP57 PF17594.2 KRH94178.1 - 2.2 8.1 5.0 5.3 6.9 0.4 2.4 1 1 1 2 2 2 0 Phage Tail fiber assembly helper gene product 57 HCMV_UL139 PF12507.8 KRH94178.1 - 3.1 8.2 6.1 1e+02 3.3 6.1 2.2 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF4988 PF16378.5 KRH94178.1 - 3.6 7.2 7.4 8 6.1 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function Snf7 PF03357.21 KRH94178.1 - 8.5 5.9 13.3 3.4 7.2 6.2 2.0 1 1 1 2 2 2 0 Snf7 DNA_ligase_ZBD PF03119.16 KRH94183.1 - 0.018 15.0 0.2 0.035 14.1 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Ser_hydrolase PF06821.13 KRH94186.1 - 0.062 13.2 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase HSP70 PF00012.20 KRH94189.1 - 1.2e-160 535.6 8.6 3.6e-88 296.3 0.2 2.8 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KRH94189.1 - 1.6e-08 33.8 0.1 0.0026 16.6 0.0 3.5 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.6 KRH94189.1 - 1.8e-05 25.1 0.0 0.078 13.4 0.0 3.2 2 2 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 KRH94189.1 - 0.0054 16.0 1.2 0.098 11.9 0.0 3.1 4 0 0 4 4 4 1 StbA protein Hydantoinase_A PF01968.18 KRH94189.1 - 0.0068 15.7 0.1 1.6 7.9 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FGGY_C PF02782.16 KRH94189.1 - 0.024 14.4 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FRB_dom PF08771.11 KRH94189.1 - 2.9 8.4 5.4 1.8 9.0 0.2 2.7 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain PepSY_like PF11396.8 KRH94190.1 - 0.09 13.3 3.5 0.14 12.8 2.9 1.6 1 1 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like Integrase_H2C2 PF17921.1 KRH94191.1 - 6.8e-05 22.9 0.4 0.00019 21.4 0.4 1.8 1 1 0 1 1 1 1 Integrase zinc binding domain zf-HC2 PF13490.6 KRH94191.1 - 0.0076 16.5 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 Putative zinc-finger RT_RNaseH PF17917.1 KRH94191.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Rer1 PF03248.13 KRH94192.1 - 1.2e-57 194.3 8.5 1.4e-57 194.2 8.5 1.0 1 0 0 1 1 1 1 Rer1 family Halogen_Hydrol PF10112.9 KRH94192.1 - 0.0077 16.3 1.5 2.8 7.9 0.7 2.1 2 0 0 2 2 2 2 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4131 PF13567.6 KRH94192.1 - 0.043 13.5 5.5 0.056 13.1 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 KRH94192.1 - 5.5 5.6 7.8 17 4.0 7.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_pol_Rpb4 PF03874.16 KRH94193.1 - 1.2e-14 54.7 1.0 1.7e-14 54.2 1.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 FYRC PF05965.14 KRH94193.1 - 0.014 15.5 0.1 0.033 14.4 0.0 1.6 2 0 0 2 2 2 0 F/Y rich C-terminus HRDC PF00570.23 KRH94193.1 - 0.077 13.0 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 HRDC domain LUC7 PF03194.15 KRH94194.1 - 7.9e-07 29.0 12.7 9.6e-06 25.4 12.7 2.2 1 1 0 1 1 1 1 LUC7 N_terminus Vif PF00559.17 KRH94194.1 - 0.042 13.6 0.3 0.071 12.8 0.3 1.4 1 0 0 1 1 1 0 Retroviral Vif (Viral infectivity) protein DUF2408 PF10303.9 KRH94194.1 - 1 9.9 6.6 1.3 9.6 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Peptidase_C13 PF01650.18 KRH94195.1 - 7.9e-21 74.7 0.1 9.4e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 KRH94195.1 - 2.4e-06 27.7 0.1 3e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Caspase domain YflT PF11181.8 KRH94195.1 - 0.0036 17.8 0.1 5 7.7 0.0 2.3 2 0 0 2 2 2 2 Heat induced stress protein YflT Peptidase_C25 PF01364.18 KRH94195.1 - 0.041 13.1 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 EamA PF00892.20 KRH94196.1 - 0.01 16.0 16.1 0.01 16.0 16.1 2.6 2 1 0 2 2 2 1 EamA-like transporter family DUF4231 PF14015.6 KRH94196.1 - 0.4 11.2 0.1 0.4 11.2 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4131 PF13567.6 KRH94196.1 - 1.7 8.2 11.9 2 8.1 1.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KRH94197.1 - 2.6e-45 154.9 1.7 3.5e-34 118.4 1.5 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH94197.1 - 3.5e-24 85.5 0.1 1.7e-21 76.7 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KRH94197.1 - 4.3e-05 23.0 0.2 0.011 15.0 0.0 3.1 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KRH94197.1 - 6.8e-05 22.5 0.2 6.8e-05 22.5 0.2 2.6 2 1 0 3 3 3 1 RIO1 family APH PF01636.23 KRH94197.1 - 0.00013 21.9 0.0 0.00079 19.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KRH94197.1 - 0.00061 19.5 0.4 0.45 10.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 WaaY PF06176.11 KRH94197.1 - 0.0025 17.5 0.4 0.0025 17.5 0.4 2.4 3 0 0 3 3 3 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KRH94197.1 - 0.004 16.0 0.1 0.0063 15.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF2318 PF10080.9 KRH94197.1 - 0.012 15.7 0.2 0.042 14.0 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Kdo PF06293.14 KRH94197.1 - 0.037 13.4 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lar_restr_allev PF14354.6 KRH94197.1 - 0.097 13.1 0.5 0.19 12.1 0.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar NOT2_3_5 PF04153.18 KRH94198.1 - 9e-10 38.7 2.8 1.1e-09 38.5 2.8 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Annexin_like PF18411.1 KRH94198.1 - 0.11 12.7 0.9 0.5 10.6 0.9 2.0 1 1 0 1 1 1 0 Annexin-like domain RrnaAD PF00398.20 KRH94199.1 - 1.4e-54 185.0 0.8 1.6e-54 184.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KRH94199.1 - 9.6e-08 32.6 0.0 2.8e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KRH94199.1 - 9.5e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KRH94199.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KRH94199.1 - 0.00029 21.4 0.0 0.00068 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH94199.1 - 0.0024 17.7 0.0 0.0032 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KRH94199.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KRH94199.1 - 0.0093 16.0 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KRH94199.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 KRH94199.1 - 0.016 16.0 0.0 0.081 13.7 0.0 2.1 2 1 1 3 3 3 0 Methyltransferase domain MetW PF07021.12 KRH94199.1 - 0.02 14.5 0.1 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KRH94199.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KRH94199.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1133 PF06576.11 KRH94199.1 - 0.17 11.3 1.0 9.6 5.6 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1133) Methyltransf_23 PF13489.6 KRH94199.1 - 0.19 11.5 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF4261 PF14080.6 KRH94202.1 - 0.16 12.1 0.6 0.53 10.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4261) Baculo_LEF-2 PF03041.14 KRH94202.1 - 0.22 11.2 7.0 0.52 10.0 2.3 2.0 2 0 0 2 2 2 0 lef-2 Exonuc_VII_L PF02601.15 KRH94202.1 - 1 8.9 5.6 1.1 8.7 5.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit rve PF00665.26 KRH94203.1 - 1.4e-12 47.8 0.1 1.9e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KRH94203.1 - 0.0053 16.5 0.1 0.0099 15.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain LIF_OSM PF01291.17 KRH94207.1 - 0.11 12.6 1.9 2.7 8.1 0.2 2.1 1 1 1 2 2 2 0 LIF / OSM family rve_3 PF13683.6 KRH94209.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain SNF2_N PF00176.23 KRH94210.1 - 5.3e-11 41.8 0.0 5.3e-11 41.8 0.0 3.0 2 2 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.8 KRH94210.1 - 0.33 10.8 11.9 10 6.0 0.3 4.6 2 1 2 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like Patatin PF01734.22 KRH94210.1 - 6.6 6.8 7.4 27 4.8 6.8 2.2 1 1 1 2 2 2 0 Patatin-like phospholipase TFIIA PF03153.13 KRH94210.1 - 7 6.5 39.6 9.4 6.1 39.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.29 KRH94211.1 - 2.5e-07 30.5 0.3 2.5e-07 30.5 0.3 3.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KRH94211.1 - 2.9e-05 24.3 6.3 2.9e-05 24.3 6.3 3.8 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein PAZ PF02170.22 KRH94211.1 - 0.0049 16.7 1.9 0.0049 16.7 1.9 2.8 2 1 0 2 2 2 1 PAZ domain UBA PF00627.31 KRH94211.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Ipi1_N PF12333.8 KRH94211.1 - 0.22 12.1 1.0 8.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation bZIP_1 PF00170.21 KRH94211.1 - 0.31 11.2 8.6 0.26 11.4 5.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor Hydrolase PF00702.26 KRH94213.1 - 9.2e-12 45.7 0.0 1.3e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Herpes_UL79 PF03049.14 KRH94213.1 - 0.12 12.0 2.7 0.21 11.2 2.7 1.3 1 0 0 1 1 1 0 UL79 family DS PF01916.17 KRH94215.1 - 4.6e-47 160.7 0.2 5.8e-37 127.5 0.1 2.0 1 1 1 2 2 2 2 Deoxyhypusine synthase MSG PF02349.15 KRH94215.1 - 1.4 9.2 6.8 7.1 6.9 0.3 3.4 2 2 1 3 3 3 0 Major surface glycoprotein UPF0113 PF03657.13 KRH94216.1 - 9.2e-23 80.3 0.2 2.8e-22 78.7 0.1 1.9 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 KRH94216.1 - 1.2e-18 67.4 4.4 2.5e-18 66.4 4.4 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KRH94216.1 - 1.5e-06 28.0 0.0 3.1e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 PUA domain DUF3194 PF11419.8 KRH94216.1 - 0.091 13.1 0.2 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3194) Ycf70 PF17382.2 KRH94218.1 - 0.14 12.6 0.0 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized Ycf70-like PepSY_TM_like_2 PF16357.5 KRH94218.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative PepSY_TM-like tRNA-synt_1e PF01406.19 KRH94219.1 - 1.5e-86 290.5 4.3 3e-58 197.5 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KRH94219.1 - 1.5e-06 27.3 0.9 0.00056 18.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KRH94219.1 - 2.4e-06 26.1 0.2 0.0048 15.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1d PF00750.19 KRH94219.1 - 0.012 14.6 0.3 0.05 12.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1f PF01921.18 KRH94219.1 - 0.094 11.6 0.3 0.47 9.3 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (K) DDE_Tnp_1_7 PF13843.6 KRH94221.1 - 0.00099 18.5 0.1 0.00099 18.5 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 RT_RNaseH PF17917.1 KRH94222.1 - 3.1e-29 101.3 0.0 5.6e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94222.1 - 1.2e-28 99.1 0.0 4.3e-28 97.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH94222.1 - 6.9e-25 87.9 0.1 1.6e-24 86.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH94222.1 - 7.1e-05 22.7 0.7 0.00013 21.8 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle ScdA_N PF04405.14 KRH94222.1 - 0.12 12.1 0.3 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) rve PF00665.26 KRH94223.1 - 5.2e-08 33.1 0.0 5.4e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain p25-alpha PF05517.12 KRH94223.1 - 0.054 13.7 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 p25-alpha DUF4710 PF15828.5 KRH94226.1 - 6.9 6.9 7.9 0.44 10.7 1.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4710) DDE_Tnp_IS1595 PF12762.7 KRH94228.1 - 1.8e-26 93.0 1.3 5.4e-26 91.4 0.3 2.1 3 0 0 3 3 3 1 ISXO2-like transposase domain DNA_ligase_ZBD PF03119.16 KRH94228.1 - 0.00024 21.0 0.4 0.00046 20.1 0.4 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain T4_baseplate PF12322.8 KRH94228.1 - 0.00027 20.5 0.5 0.00066 19.2 0.5 1.7 1 1 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.19 KRH94228.1 - 0.013 15.3 0.2 0.032 14.0 0.2 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-ACC PF17848.1 KRH94228.1 - 0.019 15.0 0.2 0.054 13.6 0.2 1.8 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KRH94228.1 - 0.088 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain RVT_1 PF00078.27 KRH94229.1 - 1e-26 93.8 1.4 1e-26 93.8 1.4 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH94229.1 - 1e-22 80.0 0.0 3.1e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94229.1 - 1.2e-22 80.2 0.0 3.7e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH94229.1 - 5.7e-16 58.8 0.0 1.2e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH94229.1 - 1.1e-08 35.1 0.0 3.5e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KRH94229.1 - 1.4e-05 25.5 0.0 3.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KRH94229.1 - 3.4e-05 23.6 0.2 8e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KRH94229.1 - 7e-05 23.4 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag_pre-integrs PF13976.6 KRH94229.1 - 0.00062 19.6 0.1 0.0018 18.1 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Asp_protease PF09668.10 KRH94229.1 - 0.0091 15.8 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease WIYLD PF10440.9 KRH94229.1 - 0.026 14.3 0.2 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain GCS PF03074.16 KRH94232.1 - 5.5e-43 147.7 4.6 1.8e-33 116.4 6.6 2.3 2 0 0 2 2 2 2 Glutamate-cysteine ligase EamA PF00892.20 KRH94233.1 - 0.00011 22.4 12.0 0.00011 22.4 12.0 2.7 2 1 0 2 2 2 1 EamA-like transporter family RseC_MucC PF04246.12 KRH94233.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.3 2 2 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC FeoB_associated PF12669.7 KRH94233.1 - 1.1 9.7 5.4 18 5.9 0.0 4.0 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein MCM PF00493.23 KRH94235.1 - 1.4e-69 233.6 1.6 2.4e-69 232.9 1.6 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH94235.1 - 4.1e-26 91.3 0.0 9e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRH94235.1 - 2.7e-20 72.6 0.3 9.3e-20 70.8 0.1 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KRH94235.1 - 4.7e-06 26.1 0.1 1.6e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRH94235.1 - 0.0052 16.8 0.1 0.017 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KRH94235.1 - 0.0067 16.9 0.1 0.024 15.0 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynein_light PF01221.18 KRH94236.1 - 4.4e-12 46.1 0.1 5.9e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3646 PF12362.8 KRH94236.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.7 1 1 1 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal BTG PF07742.12 KRH94236.1 - 0.064 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 BTG family RINT1_TIP1 PF04437.13 KRH94237.1 - 3.4e-12 46.0 11.6 3.4e-12 46.0 11.6 3.7 2 1 2 4 4 4 2 RINT-1 / TIP-1 family Ferritin PF00210.24 KRH94237.1 - 0.013 15.5 3.8 0.013 15.5 3.8 2.3 3 0 0 3 3 3 0 Ferritin-like domain DUF5446 PF17522.2 KRH94237.1 - 4.6 7.5 8.5 1.4 9.1 2.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5446) EamA PF00892.20 KRH94238.1 - 5.2e-05 23.4 8.2 5.2e-05 23.4 8.2 2.8 2 2 0 2 2 2 1 EamA-like transporter family Zip PF02535.22 KRH94240.1 - 0.23 10.6 0.5 0.36 10.0 0.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MDFI PF15316.6 KRH94240.1 - 6.3 6.9 8.8 1.3 9.1 4.5 1.9 2 1 0 2 2 2 0 MyoD family inhibitor AbLIM_anchor PF16182.5 KRH94244.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM T2SSM PF04612.12 KRH94247.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF547 PF04784.14 KRH94247.1 - 0.2 11.7 5.2 1.5 8.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function, DUF547 Gla PF00594.20 KRH94247.1 - 0.42 10.9 2.7 1.8 8.8 2.7 2.2 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Viral_Beta_CD PF04530.12 KRH94248.1 - 0.14 12.4 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family Thioredoxin_7 PF13899.6 KRH94252.1 - 0.097 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like CNDH2_N PF06278.11 KRH94252.1 - 0.35 11.1 6.4 0.62 10.3 3.8 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal bZIP_1 PF00170.21 KRH94252.1 - 0.35 11.0 8.1 3.9 7.6 2.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor FapA PF03961.13 KRH94252.1 - 4.6 5.7 7.0 6.2 5.3 7.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A WD40 PF00400.32 KRH94253.1 - 1.8e-12 47.5 6.5 0.055 14.4 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 KRH94253.1 - 1.4e-05 25.1 3.5 2.3 8.3 0.0 5.5 5 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 KRH94253.1 - 0.0024 18.1 0.0 8.5 6.8 0.0 3.5 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FlaC_arch PF05377.11 KRH94254.1 - 0.0062 16.9 1.6 0.014 15.8 0.4 1.9 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) Cut8 PF08559.10 KRH94254.1 - 0.01 15.5 0.1 0.012 15.3 0.1 1.0 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein DASH_Dam1 PF08653.10 KRH94254.1 - 0.061 13.1 1.6 0.1 12.4 1.5 1.6 1 1 0 1 1 1 0 DASH complex subunit Dam1 DASH_Hsk3 PF08227.11 KRH94254.1 - 0.071 13.5 0.7 0.14 12.5 0.7 1.6 1 1 0 1 1 1 0 DASH complex subunit Hsk3 like DASH_Dad3 PF08656.10 KRH94255.1 - 0.0018 18.3 0.8 0.016 15.3 0.2 2.9 2 0 0 2 2 2 1 DASH complex subunit Dad3 Pyr_redox_2 PF07992.14 KRH94256.1 - 1.1e-48 166.0 0.9 1.2e-48 165.8 0.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KRH94256.1 - 4.2e-27 95.2 4.3 1.3e-24 87.0 0.1 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KRH94256.1 - 1e-13 51.6 8.4 1.9e-13 50.7 0.2 3.3 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KRH94256.1 - 6.1e-08 32.2 3.9 0.0071 15.5 0.2 4.0 4 0 0 4 4 4 3 Glucose inhibited division protein A HI0933_like PF03486.14 KRH94256.1 - 2.7e-06 26.4 1.1 0.002 16.9 0.0 3.2 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.6 KRH94256.1 - 0.00014 21.2 1.5 0.0048 16.1 0.1 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KRH94256.1 - 0.00081 18.6 1.4 1.4 7.9 0.1 3.8 3 1 1 4 4 4 1 FAD binding domain NAD_binding_7 PF13241.6 KRH94256.1 - 0.006 17.0 0.3 0.036 14.5 0.0 2.4 3 0 0 3 3 3 1 Putative NAD(P)-binding Thi4 PF01946.17 KRH94256.1 - 0.015 14.6 2.3 0.1 11.8 0.2 2.7 3 0 0 3 3 3 0 Thi4 family DAO PF01266.24 KRH94256.1 - 0.017 14.7 4.2 0.13 11.8 0.0 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KRH94256.1 - 0.023 13.8 0.8 1.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KRH94256.1 - 0.49 10.4 3.3 0.74 9.8 0.1 2.6 3 1 0 3 3 3 0 FAD-NAD(P)-binding XPA_C PF05181.12 KRH94257.1 - 4.7e-17 61.7 0.0 9.3e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Elf4 PF07011.11 KRH94257.1 - 0.06 13.3 0.6 0.12 12.3 0.2 1.7 2 0 0 2 2 2 0 Early Flowering 4 domain CK_II_beta PF01214.18 KRH94258.1 - 1.2e-50 171.8 0.3 1.6e-50 171.5 0.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PBCV_basic_adap PF08789.10 KRH94260.1 - 0.047 13.8 1.0 0.23 11.6 0.1 2.4 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain Lactamase_B_2 PF12706.7 KRH94261.1 - 7.8e-16 58.2 0.4 1.2e-06 28.2 0.0 3.0 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KRH94261.1 - 5.3e-05 22.8 0.0 0.0014 18.2 0.0 2.6 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KRH94261.1 - 0.00042 20.4 0.1 0.0069 16.4 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pox_F15 PF04596.12 KRH94261.1 - 0.34 10.7 3.9 0.83 9.4 0.1 2.7 2 1 1 3 3 3 0 Poxvirus protein F15 Metallophos PF00149.28 KRH94262.1 - 1.9e-30 106.9 0.0 4.1e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase APG17 PF04108.12 KRH94262.1 - 0.015 14.4 4.2 0.03 13.4 4.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Gag_p12 PF01141.18 KRH94262.1 - 0.046 14.1 0.3 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Ribosomal_S25 PF03297.15 KRH94264.1 - 3.6e-23 81.7 5.3 3.6e-23 81.7 5.3 1.5 1 1 1 2 2 2 1 S25 ribosomal protein HTH_45 PF14947.6 KRH94264.1 - 0.0061 16.5 0.2 0.0093 15.9 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix Mlp PF03304.13 KRH94265.1 - 0.046 14.0 1.9 0.066 13.4 1.9 1.4 1 1 0 1 1 1 0 Mlp lipoprotein family MutL_C PF08676.11 KRH94266.1 - 4.1e-09 36.4 0.5 1.3e-08 34.7 0.3 2.0 1 1 1 2 2 2 1 MutL C terminal dimerisation domain GLTSCR1 PF15249.6 KRH94267.1 - 3.5e-06 27.4 0.3 3.5e-06 27.4 0.3 2.1 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein rve PF00665.26 KRH94270.1 - 1.2e-21 77.1 0.1 3.1e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 KRH94270.1 - 0.00017 21.3 4.1 0.0007 19.4 4.0 2.2 1 1 0 1 1 1 1 GAG-pre-integrase domain Integrase_H2C2 PF17921.1 KRH94270.1 - 0.022 14.9 1.1 0.022 14.9 1.1 2.7 4 0 0 4 4 4 0 Integrase zinc binding domain rve_3 PF13683.6 KRH94270.1 - 0.051 13.3 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Integrase core domain Phage_integr_3 PF16795.5 KRH94270.1 - 0.12 12.2 0.9 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 Archaeal phage integrase RVT_1 PF00078.27 KRH94271.1 - 6.4e-09 35.6 0.2 9.8e-09 35.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KRH94272.1 - 4.8e-10 39.9 0.0 7.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94272.1 - 3.9e-08 33.8 0.1 6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH94272.1 - 1e-05 25.3 0.2 1.8e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KRH94272.1 - 0.0014 18.9 0.0 0.0038 17.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 KRH94272.1 - 0.0023 17.7 0.2 0.021 14.6 0.2 2.1 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.10 KRH94272.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease partial_CstF PF15861.5 KRH94273.1 - 0.16 11.7 1.3 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain zf-CRD PF17979.1 KRH94273.1 - 0.32 11.1 4.2 2.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-C4_Topoisom PF01396.19 KRH94275.1 - 0.0054 16.5 1.6 0.0097 15.7 1.6 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger PUF PF00806.19 KRH94275.1 - 0.021 14.5 0.4 0.047 13.4 0.4 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat zf-LITAF-like PF10601.9 KRH94275.1 - 0.03 14.6 4.1 0.095 13.0 4.1 1.8 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain PH PF00169.29 KRH94276.1 - 0.071 13.6 0.1 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 PH domain SOGA PF11365.8 KRH94277.1 - 0.032 15.4 1.1 0.032 15.4 1.1 4.2 4 1 0 4 4 4 0 Protein SOGA ThiS PF02597.20 KRH94277.1 - 1.2 9.8 4.7 11 6.7 0.1 3.4 3 0 0 3 3 3 0 ThiS family Pox_A_type_inc PF04508.12 KRH94277.1 - 7.1 6.7 10.0 36 4.4 0.4 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Transcrip_act PF04949.13 KRH94278.1 - 0.047 13.6 0.6 0.12 12.2 0.6 1.7 1 0 0 1 1 1 0 Transcriptional activator DUF3413 PF11893.8 KRH94280.1 - 0.86 8.7 5.8 1.3 8.2 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Pkr1 PF08636.10 KRH94280.1 - 5.7 7.1 10.1 0.93 9.7 4.6 2.3 2 1 1 3 3 3 0 ER protein Pkr1 GTP_EFTU PF00009.27 KRH94282.1 - 6.2e-35 120.5 0.1 6.6e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KRH94282.1 - 8.1e-08 32.4 0.1 3.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 KRH94282.1 - 0.0082 15.8 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain gag-asp_proteas PF13975.6 KRH94283.1 - 8.7e-06 26.2 0.0 1.5e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94283.1 - 1e-05 26.1 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH94283.1 - 4.7e-05 23.2 0.2 7.7e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease PBP-Tp47_a PF14889.6 KRH94283.1 - 0.064 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a FecR PF04773.13 KRH94283.1 - 0.11 13.1 0.2 0.39 11.4 0.1 1.9 1 1 1 2 2 2 0 FecR protein RT_RNaseH PF17917.1 KRH94287.1 - 6.9e-27 93.8 0.0 1.6e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94287.1 - 3.4e-21 75.1 0.0 7.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH94287.1 - 3.6e-19 69.1 0.0 2.6e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH94287.1 - 2e-06 27.8 0.7 4.2e-06 26.8 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain MLVIN_C PF18697.1 KRH94287.1 - 0.0008 19.5 0.1 0.0025 17.8 0.1 1.9 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain bVLRF1 PF18826.1 KRH94287.1 - 0.078 12.9 0.9 0.19 11.6 0.1 2.0 2 1 0 2 2 2 0 bacteroidetes VLRF1 release factor zf-H2C2 PF09337.10 KRH94287.1 - 0.12 12.6 0.9 0.27 11.5 0.9 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Occludin_ELL PF07303.13 KRH94287.1 - 0.47 11.2 3.2 12 6.7 0.1 3.2 3 1 0 3 3 3 0 Occludin homology domain SICA_beta PF12878.7 KRH94287.1 - 2.1 8.5 8.1 5.4 7.2 1.0 3.3 3 1 0 3 3 3 0 SICA extracellular beta domain RVT_1 PF00078.27 KRH94288.1 - 7.9e-27 94.2 0.4 2.1e-26 92.8 0.4 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 KRH94288.1 - 2.8e-08 34.2 0.1 5.7e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94288.1 - 4.3e-08 33.7 0.1 8.4e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH94288.1 - 1.4e-05 25.3 0.3 7.6e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.11 KRH94288.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH94288.1 - 0.027 14.3 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_thumb PF06817.14 KRH94288.1 - 0.027 14.3 0.2 0.094 12.6 0.2 1.9 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Chlor_dismutase PF06778.12 KRH94288.1 - 0.093 12.3 0.5 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Chlorite dismutase GP4 PF03010.14 KRH94291.1 - 0.11 12.4 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 GP4 CAMSAP_CH PF11971.8 KRH94292.1 - 0.081 12.8 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 CAMSAP CH domain Integrase_H2C2 PF17921.1 KRH94295.1 - 3.1e-10 40.0 0.0 7.8e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KRH94295.1 - 2.3e-06 28.1 0.2 1e-05 26.0 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94295.1 - 7.7e-06 26.5 0.1 1.6e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease eIF3g PF12353.8 KRH94295.1 - 0.00047 20.5 0.6 0.0016 18.9 0.6 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Retrotrans_gag PF03732.17 KRH94295.1 - 0.012 15.8 0.2 8.2 6.8 0.0 2.7 1 1 1 2 2 2 0 Retrotransposon gag protein RVP PF00077.20 KRH94295.1 - 0.044 14.1 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 KRH94295.1 - 0.095 12.5 0.1 0.28 11.0 0.1 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-RanBP PF00641.18 KRH94295.1 - 3.9 6.9 5.7 25 4.3 0.1 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Chordopox_E11 PF06138.12 KRH94296.1 - 0.088 13.1 3.2 0.13 12.6 0.4 2.4 2 1 1 3 3 3 0 Chordopoxvirus E11 protein bZIP_1 PF00170.21 KRH94298.1 - 0.041 14.0 11.1 0.038 14.1 8.0 2.6 1 1 1 2 2 2 0 bZIP transcription factor CfAFP PF05264.11 KRH94298.1 - 0.38 10.7 2.7 0.7 9.9 2.7 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) DDE_Tnp_IS1595 PF12762.7 KRH94301.1 - 1.4e-16 60.9 0.4 1.7e-16 60.6 0.4 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Baculo_p24 PF05073.12 KRH94304.1 - 0.0064 16.3 3.9 0.0092 15.8 3.9 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein PDDEXK_6 PF04720.12 KRH94304.1 - 0.08 12.9 0.8 0.17 11.8 0.1 1.8 1 1 1 2 2 2 0 PDDEXK-like family of unknown function Tsg PF04668.12 KRH94304.1 - 0.082 13.6 2.3 0.12 13.0 2.3 1.2 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region BDM PF10684.9 KRH94304.1 - 0.2 12.0 0.9 0.6 10.5 0.2 2.0 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein RVT_1 PF00078.27 KRH94305.1 - 8.1e-24 84.4 0.1 9.2e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cas_Csx8 PF09657.10 KRH94305.1 - 0.00097 18.2 0.5 0.0011 18.1 0.5 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Csx8 (Cas_Csx8) DUF4883 PF16224.5 KRH94305.1 - 0.019 15.2 2.0 0.026 14.8 2.0 1.2 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) RNase_Zc3h12a PF11977.8 KRH94305.1 - 0.028 14.2 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain RVT_2 PF07727.14 KRH94305.1 - 0.044 13.4 0.3 0.064 12.9 0.3 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MAM PF00629.23 KRH94305.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Trp_ring PF18669.1 KRH94305.1 - 0.11 12.7 1.3 2.5 8.4 0.4 2.5 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain DUF3175 PF11373.8 KRH94308.1 - 0.072 13.3 1.4 0.24 11.6 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) Prp19 PF08606.11 KRH94309.1 - 0.075 13.0 0.9 0.18 11.8 0.9 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like gag-asp_proteas PF13975.6 KRH94311.1 - 0.083 13.5 0.0 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 KRH94312.1 - 6.9e-13 48.6 0.0 7.7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 KRH94312.1 - 0.029 14.0 0.1 0.18 11.4 0.1 1.8 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH94313.1 - 9.1e-17 61.3 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_E_B PF04042.16 KRH94318.1 - 4e-14 52.5 0.5 7.3e-14 51.6 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B OGG_N PF07934.12 KRH94319.1 - 1e-13 51.4 0.8 3.1e-13 49.9 0.8 1.8 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KRH94319.1 - 0.059 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF778 PF05608.12 KRH94320.1 - 0.067 13.6 0.4 0.18 12.2 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF778) XPG_N PF00752.17 KRH94320.1 - 0.14 12.7 2.4 3 8.4 0.7 2.6 2 0 0 2 2 2 0 XPG N-terminal domain LAP1C PF05609.12 KRH94321.1 - 0.00019 20.7 3.9 0.00024 20.3 3.9 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 KRH94321.1 - 4.3 6.0 9.1 3.4 6.3 4.5 2.1 2 0 0 2 2 2 0 Presenilin Carb_kinase PF01256.17 KRH94323.1 - 1.8e-30 106.2 0.0 7.4e-29 100.9 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase LRR_4 PF12799.7 KRH94324.1 - 0.038 14.4 36.7 0.051 14.0 5.5 6.7 2 2 5 7 7 7 0 Leucine Rich repeats (2 copies) Terminase_3 PF04466.13 KRH94324.1 - 0.14 11.7 5.1 0.059 12.9 0.5 2.6 2 1 1 3 3 3 0 Phage terminase large subunit LRR_1 PF00560.33 KRH94324.1 - 3.9 8.4 31.7 54 4.9 0.1 9.3 8 1 0 8 8 8 0 Leucine Rich Repeat Bac_export_2 PF01312.19 KRH94325.1 - 0.16 11.1 3.1 0.18 11.0 3.1 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DDE_3 PF13358.6 KRH94326.1 - 0.0054 16.5 0.0 0.0068 16.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3603 PF12227.8 KRH94326.1 - 0.0077 15.6 0.0 0.009 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3603) rve PF00665.26 KRH94329.1 - 0.013 15.7 0.0 0.013 15.7 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain RT_RNaseH PF17917.1 KRH94330.1 - 1.5e-32 112.0 0.0 4.5e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94330.1 - 1.6e-31 108.3 0.0 5e-31 106.7 0.0 1.9 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH94330.1 - 1.6e-14 53.8 1.0 2.8e-14 52.9 1.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH94330.1 - 6.9e-11 42.4 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 KRH94330.1 - 7.1e-05 22.9 1.5 0.00012 22.2 0.7 1.8 2 0 0 2 2 2 1 H2C2 zinc finger DUF5401 PF17380.2 KRH94330.1 - 3.3 5.7 13.5 4.3 5.3 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RVT_1 PF00078.27 KRH94331.1 - 0.013 15.0 0.3 0.014 14.9 0.3 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KRH94332.1 - 1.8e-11 44.0 0.3 3.9e-11 42.9 0.3 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 KRH94333.1 - 2.6e-05 24.1 2.1 5.3e-05 23.1 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KRH94333.1 - 0.0099 15.6 0.9 0.024 14.4 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.20 KRH94333.1 - 0.098 12.5 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 CHC2 zinc finger RT_RNaseH_2 PF17919.1 KRH94334.1 - 3.2e-26 91.3 0.0 5.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94334.1 - 3.6e-25 88.3 0.0 1e-24 86.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MafB19-deam PF14437.6 KRH94334.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase RVT_thumb PF06817.14 KRH94334.1 - 0.032 14.1 0.1 0.064 13.1 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_1 PF00078.27 KRH94335.1 - 0.0022 17.6 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PilJ_C PF18223.1 KRH94336.1 - 0.088 13.3 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Pili PilJ C-terminal domain tRNA-synt_2d PF01409.20 KRH94337.1 - 1.1e-83 280.4 0.0 1.8e-83 279.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 KRH94337.1 - 4.9e-08 32.7 0.0 3.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 KRH94337.1 - 0.0022 18.2 1.5 0.0098 16.2 0.4 2.7 2 1 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 KRH94337.1 - 0.0059 15.7 2.1 0.019 14.0 0.1 2.5 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) RuvC PF02075.17 KRH94337.1 - 0.038 13.9 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC ABC_tran PF00005.27 KRH94338.1 - 5.6e-25 88.4 0.0 1e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KRH94338.1 - 2.5e-07 30.4 0.5 6e-07 29.1 0.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRH94338.1 - 1.9e-06 27.9 2.4 0.0005 20.0 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KRH94338.1 - 2.9e-05 24.3 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KRH94338.1 - 0.00058 20.4 2.4 0.0021 18.6 2.4 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH94338.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 KRH94338.1 - 0.0021 18.3 0.0 0.029 14.6 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KRH94338.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KRH94338.1 - 0.0028 17.7 0.1 0.0064 16.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 KRH94338.1 - 0.0038 17.6 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KRH94338.1 - 0.0093 15.9 0.6 3.3 7.6 0.1 2.4 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 KRH94338.1 - 0.01 15.6 0.7 0.057 13.1 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 KRH94338.1 - 0.013 15.2 0.3 0.043 13.6 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KRH94338.1 - 0.031 13.3 0.2 0.056 12.5 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KRH94338.1 - 0.036 14.2 0.4 0.13 12.4 0.1 1.9 1 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.14 KRH94338.1 - 0.038 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KRH94338.1 - 0.046 14.1 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 KRH94338.1 - 0.055 13.0 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KRH94338.1 - 0.065 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 KRH94338.1 - 0.071 13.2 0.1 1.1 9.3 0.0 2.6 1 1 1 2 2 2 0 AAA domain Roc PF08477.13 KRH94338.1 - 0.078 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 KRH94338.1 - 0.095 13.0 0.1 0.43 10.9 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KRH94338.1 - 0.11 12.5 0.2 2.3 8.2 0.1 2.8 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KRH94338.1 - 0.12 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_30 PF13604.6 KRH94338.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KRH94338.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KRH94338.1 - 0.26 11.7 2.5 3.2 8.2 1.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DivIC PF04977.15 KRH94340.1 - 0.5 10.2 7.0 1.2 8.9 0.1 4.1 4 0 0 4 4 4 0 Septum formation initiator GH43_C2 PF17851.1 KRH94341.1 - 0.034 13.9 1.2 0.064 13.0 1.2 1.4 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain RabGAP-TBC PF00566.18 KRH94345.1 - 7e-37 127.2 10.8 1.2e-36 126.4 10.8 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PTH2 PF01981.16 KRH94348.1 - 1.3e-13 51.3 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Peptidase_M24 PF00557.24 KRH94349.1 - 1.3e-26 93.6 0.0 2.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KRH94349.1 - 2.1e-22 79.9 0.9 2.1e-22 79.9 0.9 2.5 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KRH94349.1 - 1.4e-16 60.3 1.2 3.6e-16 59.0 1.2 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KRH94349.1 - 4.1e-10 40.4 0.0 1.4e-09 38.7 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain HECT PF00632.25 KRH94350.1 - 3e-72 243.7 2.7 3e-72 243.7 2.7 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CAAP1 PF15335.6 KRH94350.1 - 0.0082 16.7 0.9 0.041 14.4 0.0 2.7 3 0 0 3 3 3 1 Caspase activity and apoptosis inhibitor 1 AZUL PF16558.5 KRH94350.1 - 0.0094 16.2 0.7 0.028 14.6 0.7 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PLDc_2 PF13091.6 KRH94351.1 - 8.8e-09 35.3 0.5 1.8e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.22 KRH94351.1 - 0.00087 19.4 0.3 0.0029 17.7 0.3 1.9 1 0 0 1 1 1 1 Phospholipase D Active site motif ParB PF08775.10 KRH94353.1 - 0.03 14.8 1.2 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 ParB family ATF7IP_BD PF16788.5 KRH94353.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.4 3 0 0 3 3 3 0 ATF-interacting protein binding domain DDE_Tnp_IS1595 PF12762.7 KRH94354.1 - 1.4e-09 38.2 0.4 1.5e-09 38.1 0.4 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain MIP-T3_C PF17749.1 KRH94355.1 - 0.74 9.8 4.7 1.1 9.2 0.3 2.5 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Tfb4 PF03850.14 KRH94356.1 - 1.5e-08 34.5 18.7 4.9e-05 23.0 5.1 3.1 2 1 1 3 3 3 3 Transcription factor Tfb4 E1-E2_ATPase PF00122.20 KRH94358.1 - 4.4e-21 75.2 8.6 1.5e-10 40.9 0.6 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KRH94358.1 - 6.4e-20 72.3 0.9 1.9e-19 70.8 0.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KRH94358.1 - 1e-12 48.1 11.3 6.5e-07 29.2 4.3 3.6 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus PI3K_C2 PF00792.24 KRH94358.1 - 0.0018 18.2 1.8 0.0076 16.2 1.8 2.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PDZ_3 PF17815.1 KRH94358.1 - 0.006 16.4 0.0 0.52 10.2 0.0 3.1 3 1 0 3 3 3 1 PDZ domain DUF3825 PF12873.7 KRH94358.1 - 0.017 14.6 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Hydrolase_3 PF08282.12 KRH94358.1 - 0.023 14.4 0.5 0.023 14.4 0.5 4.9 3 2 2 5 5 5 0 haloacid dehalogenase-like hydrolase HTH_Tnp_Tc3_2 PF01498.18 KRH94358.1 - 0.4 11.0 2.4 1 9.7 2.4 1.7 1 0 0 1 1 1 0 Transposase TFIIE_beta PF02186.15 KRH94358.1 - 0.46 10.8 4.2 0.44 10.9 0.2 3.1 2 1 1 3 3 3 0 TFIIE beta subunit core domain Helicase_C PF00271.31 KRH94359.1 - 2.7e-15 56.7 2.1 1.1e-14 54.7 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KRH94359.1 - 5.1e-06 26.4 0.2 2e-05 24.4 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KRH94359.1 - 0.00081 19.7 0.2 0.0028 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KRH94359.1 - 0.0064 16.2 0.2 0.031 14.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KRH94359.1 - 0.055 13.5 0.2 0.29 11.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRH94359.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Coat_X PF07552.11 KRH94359.1 - 0.092 12.6 0.3 0.25 11.2 0.3 1.7 1 0 0 1 1 1 0 Spore Coat Protein X and V domain HA2 PF04408.23 KRH94359.1 - 0.18 12.1 0.0 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 Helicase associated domain (HA2) Ribosomal_L27A PF00828.19 KRH94360.1 - 1.6e-18 67.6 0.3 2.1e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DGOK PF05035.12 KRH94360.1 - 0.14 11.0 0.1 0.39 9.6 0.1 1.6 1 1 1 2 2 2 0 2-keto-3-deoxy-galactonokinase DEAD PF00270.29 KRH94361.1 - 5.5e-32 110.9 1.8 1e-31 110.1 1.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH94361.1 - 2e-23 82.9 1.1 2e-22 79.7 0.0 3.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KRH94361.1 - 2.9e-11 43.4 0.5 7.6e-11 42.1 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KRH94361.1 - 2e-09 37.7 0.3 2e-09 37.7 0.3 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KRH94361.1 - 0.014 15.5 0.2 0.036 14.2 0.2 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain Cullin_Nedd8 PF10557.9 KRH94361.1 - 0.068 13.2 1.4 0.25 11.4 0.8 2.3 2 0 0 2 2 2 0 Cullin protein neddylation domain Flavi_DEAD PF07652.14 KRH94361.1 - 0.17 11.9 0.2 0.55 10.2 0.2 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KRH94361.1 - 0.87 9.9 3.6 8.8 6.6 1.0 3.2 2 1 0 2 2 2 0 AAA domain IZUMO PF15005.6 KRH94361.1 - 9.6 6.7 6.8 2.1 8.9 2.4 2.2 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DNA_ligase_ZBD PF03119.16 KRH94362.1 - 0.00059 19.8 0.7 0.0011 18.9 0.7 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.19 KRH94362.1 - 0.003 17.3 0.6 0.0071 16.1 0.5 1.8 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger T4_baseplate PF12322.8 KRH94362.1 - 0.0054 16.2 0.2 0.006 16.1 0.2 1.1 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-ACC PF17848.1 KRH94362.1 - 0.0063 16.6 0.2 0.013 15.5 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KRH94362.1 - 0.023 14.1 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KRH94362.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain rve PF00665.26 KRH94363.1 - 1e-08 35.3 0.1 3.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 KRH94363.1 - 5.3e-05 22.9 0.1 0.00012 21.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 KRH94363.1 - 0.0065 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DUF4537 PF15057.6 KRH94363.1 - 0.0089 16.1 0.2 0.015 15.4 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) NERD PF08378.11 KRH94363.1 - 0.21 12.1 2.9 0.17 12.4 0.7 1.9 1 1 1 2 2 2 0 Nuclease-related domain YukC PF10140.9 KRH94367.1 - 0.0055 15.6 1.4 0.067 12.0 0.2 2.1 2 0 0 2 2 2 2 WXG100 protein secretion system (Wss), protein YukC Lebercilin PF15619.6 KRH94369.1 - 0.0041 16.8 4.9 0.0053 16.4 4.9 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.13 KRH94369.1 - 0.0047 17.0 5.5 0.0054 16.8 5.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SOGA PF11365.8 KRH94369.1 - 0.015 16.4 3.3 0.019 16.1 3.3 1.1 1 0 0 1 1 1 0 Protein SOGA CRA PF06589.11 KRH94369.1 - 0.031 14.4 2.3 0.037 14.1 2.3 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) T6PP_N PF18572.1 KRH94369.1 - 0.033 14.0 3.9 0.071 13.0 3.9 1.5 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain FapA PF03961.13 KRH94369.1 - 0.1 11.2 4.7 0.11 11.0 4.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_32 PF13654.6 KRH94369.1 - 0.12 11.2 2.1 0.13 11.0 2.1 1.0 1 0 0 1 1 1 0 AAA domain LRRFIP PF09738.9 KRH94369.1 - 0.19 11.1 7.8 2.4 7.5 7.9 1.9 1 1 0 1 1 1 0 LRRFIP family DASH_Hsk3 PF08227.11 KRH94369.1 - 0.27 11.6 1.9 0.58 10.6 0.3 2.2 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like ATP-synt_D PF01813.17 KRH94369.1 - 0.58 9.9 4.6 2 8.2 4.5 1.7 1 1 0 1 1 1 0 ATP synthase subunit D ZapB PF06005.12 KRH94369.1 - 1.2 9.7 6.9 22 5.6 0.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Cytochrom_C_2 PF01322.20 KRH94370.1 - 0.017 16.0 1.8 0.022 15.6 1.8 1.2 1 0 0 1 1 1 0 Cytochrome C' AATF-Che1 PF13339.6 KRH94370.1 - 0.032 14.9 6.1 0.93 10.2 0.7 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor PCRF PF03462.18 KRH94370.1 - 0.033 14.1 3.7 0.042 13.7 3.7 1.1 1 0 0 1 1 1 0 PCRF domain YPEB PF14620.6 KRH94370.1 - 0.033 13.5 3.2 0.039 13.3 3.2 1.0 1 0 0 1 1 1 0 YpeB sporulation Seryl_tRNA_N PF02403.22 KRH94370.1 - 0.044 14.0 6.0 0.063 13.5 6.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF573 PF04504.14 KRH94370.1 - 0.05 14.3 4.1 0.11 13.2 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF573 FapA PF03961.13 KRH94370.1 - 0.09 11.4 5.2 0.1 11.2 5.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A PspB PF06667.12 KRH94370.1 - 0.12 12.4 2.1 0.19 11.8 0.3 2.0 1 1 1 2 2 2 0 Phage shock protein B DASH_Dam1 PF08653.10 KRH94370.1 - 0.19 11.6 3.7 0.95 9.3 0.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 KilA-N PF04383.13 KRH94370.1 - 0.67 9.8 6.3 4.1 7.3 0.9 2.2 1 1 1 2 2 2 0 KilA-N domain V_ATPase_I PF01496.19 KRH94370.1 - 0.8 7.5 5.4 0.84 7.5 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PdaC PF13739.6 KRH94370.1 - 4.2 8.4 7.5 1.6 9.7 0.6 2.1 1 1 1 2 2 2 0 Deacetylase PdaC DUF4187 PF13821.6 KRH94371.1 - 0.00092 18.9 6.6 0.0017 18.1 5.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 KRH94371.1 - 0.0028 17.4 0.4 0.0065 16.3 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 KRH94371.1 - 0.059 13.8 1.7 0.059 13.8 1.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRH94371.1 - 0.07 14.0 5.6 0.12 13.3 1.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3546 PF12066.8 KRH94371.1 - 2.3 8.5 10.7 0.34 11.1 5.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) zf-C2H2_2 PF12756.7 KRH94371.1 - 2.3 8.6 9.4 1.2 9.5 3.9 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 KRH94371.1 - 3.3 8.1 5.4 2.2 8.6 0.7 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LSM PF01423.22 KRH94372.1 - 8e-13 47.9 0.1 1.2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KRH94372.1 - 0.0012 18.9 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KRH94372.1 - 0.054 13.6 0.2 0.092 12.9 0.2 1.5 1 1 0 1 1 1 0 Scd6-like Sm domain SMC_N PF02463.19 KRH94373.1 - 9.6e-27 93.9 0.0 1.8e-26 92.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KRH94373.1 - 6.5e-11 43.1 25.6 6.5e-11 43.1 25.6 5.7 1 1 1 3 3 3 1 AAA domain TPR_MLP1_2 PF07926.12 KRH94373.1 - 0.00018 21.6 4.8 0.00018 21.6 4.8 5.7 3 1 3 6 6 6 2 TPR/MLP1/MLP2-like protein AAA_22 PF13401.6 KRH94373.1 - 0.0063 16.8 0.8 0.84 9.9 0.1 3.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KRH94373.1 - 0.0089 15.8 0.2 0.022 14.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 KRH94373.1 - 0.66 9.7 19.3 0.43 10.3 0.2 4.5 4 0 0 4 4 4 0 MukB N-terminal NIF PF03031.18 KRH94374.1 - 5.1e-10 39.3 0.6 1.8e-09 37.6 0.6 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2817 PF10994.8 KRH94374.1 - 0.011 15.2 0.4 0.017 14.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Sedlin_N PF04628.13 KRH94375.1 - 2.3e-09 37.5 1.3 2.5e-09 37.3 1.3 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region zf-BED PF02892.15 KRH94378.1 - 7.2 6.7 7.8 10 6.2 5.6 2.1 1 1 1 2 2 2 0 BED zinc finger MS_channel PF00924.18 KRH94379.1 - 5e-15 55.6 0.1 5e-15 55.6 0.1 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 KRH94379.1 - 2e-05 24.2 0.2 0.00011 21.8 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KRH94379.1 - 3.3e-05 23.1 1.6 0.00011 21.5 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KRH94379.1 - 0.025 14.1 0.2 0.094 12.3 0.2 2.1 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KRH94379.1 - 0.03 14.8 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Arm PF00514.23 KRH94381.1 - 1.8e-31 107.2 11.4 1e-09 38.1 0.0 8.2 7 3 0 7 7 7 5 Armadillo/beta-catenin-like repeat IBB PF01749.20 KRH94381.1 - 0.00034 21.0 1.3 0.00091 19.6 1.3 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 KRH94381.1 - 0.0016 18.5 0.5 3.1 8.3 0.0 5.0 5 1 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KRH94381.1 - 0.0029 18.1 0.1 0.23 12.0 0.0 4.1 6 2 0 6 6 6 1 HEAT-like repeat Cas6_N PF17952.1 KRH94381.1 - 0.06 13.6 0.4 0.22 11.8 0.4 2.0 1 0 0 1 1 1 0 Cas6 N-terminal domain VCBS PF13517.6 KRH94382.1 - 3.6e-06 27.5 1.4 0.0032 18.0 0.0 3.0 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KRH94382.1 - 0.024 14.8 1.4 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 FG-GAP repeat NMD3 PF04981.13 KRH94383.1 - 5.4e-56 189.8 14.1 7.6e-56 189.3 14.1 1.2 1 0 0 1 1 1 1 NMD3 family RNA_pol_3_Rpc31 PF11705.8 KRH94384.1 - 0.036 14.3 0.1 0.038 14.2 0.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Arrestin_N PF00339.29 KRH94385.1 - 0.028 14.5 5.3 0.061 13.4 0.1 3.1 3 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain zf-CSL PF05207.13 KRH94386.1 - 5e-19 67.8 0.3 7.6e-19 67.2 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 KRH94386.1 - 0.015 15.1 0.3 0.028 14.2 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L6 PF00347.23 KRH94387.1 - 2.7e-17 63.2 0.3 1.6e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 RT_RNaseH_2 PF17919.1 KRH94388.1 - 8.3e-17 61.1 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94388.1 - 4.9e-10 39.6 0.0 1e-09 38.6 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Collagen_bind PF05737.12 KRH94388.1 - 0.079 13.1 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 Collagen binding domain RVT_1 PF00078.27 KRH94389.1 - 4.2e-21 75.5 0.2 4.9e-21 75.3 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRI5 PF06330.11 KRH94389.1 - 0.0094 14.9 0.3 0.014 14.3 0.3 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) REC1 PF18501.1 KRH94389.1 - 0.017 15.0 0.4 0.021 14.7 0.4 1.1 1 0 0 1 1 1 0 Alpha helical recognition lobe domain MAM PF00629.23 KRH94389.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu BTG PF07742.12 KRH94390.1 - 0.034 14.0 0.3 0.068 13.0 0.3 1.5 1 1 0 1 1 1 0 BTG family Peptidase_M3_N PF08439.10 KRH94390.1 - 0.1 12.9 3.4 0.25 11.6 3.0 2.0 1 1 0 1 1 1 0 Oligopeptidase F PRANC PF09372.10 KRH94390.1 - 0.66 10.3 14.1 1.2 9.5 1.3 2.8 2 2 1 3 3 3 0 PRANC domain DUF4994 PF16385.5 KRH94391.1 - 0.056 13.4 0.4 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function Peptidase_C34 PF05413.11 KRH94391.1 - 0.23 11.7 2.6 1.6 9.0 0.1 2.8 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase LSM PF01423.22 KRH94394.1 - 2e-10 40.2 0.0 2.3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2052 PF09747.9 KRH94395.1 - 0.15 12.2 18.7 0.19 11.8 18.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) eIF-3c_N PF05470.12 KRH94395.1 - 0.89 7.8 20.9 1 7.6 20.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2151 PF10221.9 KRH94395.1 - 0.92 8.0 14.4 1.1 7.8 14.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF913 PF06025.12 KRH94395.1 - 2.7 6.9 11.8 3 6.8 11.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KRH94395.1 - 3.7 6.2 14.0 4.5 5.9 14.0 1.0 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 KRH94395.1 - 5.1 6.8 10.0 5.8 6.6 10.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Astro_capsid_p PF12226.8 KRH94395.1 - 6.5 5.8 14.5 8.8 5.4 14.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Vfa1 PF08432.10 KRH94395.1 - 7.4 6.9 25.1 12 6.2 25.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TP53IP5 PF15331.6 KRH94395.1 - 8.5 6.5 14.3 10 6.2 14.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Glyco_transf_36 PF06165.11 KRH94396.1 - 0.087 12.2 0.0 0.087 12.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 36 PhoLip_ATPase_C PF16212.5 KRH94397.1 - 2.4e-36 125.8 26.7 2.4e-36 125.8 26.7 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KRH94397.1 - 9.4e-13 47.7 9.4 1.3e-12 47.2 7.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KRH94397.1 - 8.9e-12 45.7 1.2 3.9e-05 24.0 1.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRH94397.1 - 1.7e-10 40.8 0.1 4.1e-09 36.4 0.0 2.9 2 1 1 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KRH94397.1 - 3.5e-10 39.7 2.7 1.5e-06 27.9 0.1 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KRH94397.1 - 0.015 15.0 0.3 0.015 15.0 0.3 4.6 4 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase Amidase_6 PF12671.7 KRH94397.1 - 0.42 10.7 3.6 0.36 10.9 0.7 2.3 2 1 0 2 2 2 0 Putative amidase domain MFS_1_like PF12832.7 KRH94398.1 - 1.3e-13 50.6 17.4 1.3e-13 50.6 17.4 2.2 1 1 1 2 2 2 1 MFS_1 like family BBP1_N PF15271.6 KRH94398.1 - 0.12 13.2 3.1 0.21 12.3 3.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein CLN3 PF02487.17 KRH94398.1 - 0.21 10.6 21.8 0.35 9.9 11.3 2.4 1 1 1 2 2 2 0 CLN3 protein MFS_1_like PF12832.7 KRH94399.1 - 2.7e-09 36.4 7.5 4.1e-09 35.8 7.5 1.2 1 0 0 1 1 1 1 MFS_1 like family DUF3671 PF12420.8 KRH94399.1 - 3.8 7.6 10.7 0.24 11.5 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function UQ_con PF00179.26 KRH94400.1 - 6e-40 136.1 0.1 7.2e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KRH94400.1 - 0.0011 19.3 0.3 0.0039 17.5 0.3 1.9 1 1 0 1 1 1 1 RWD domain Hexokinase_1 PF00349.21 KRH94401.1 - 7.6e-25 88.0 0.0 1.6e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KRH94401.1 - 5.7e-11 42.3 0.1 5.5e-07 29.3 0.2 2.2 1 1 1 2 2 2 2 Hexokinase Yos9_DD PF17880.1 KRH94401.1 - 0.0096 16.0 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 1 Yos9 dimerzation domain StbA PF06406.11 KRH94401.1 - 0.012 14.9 0.5 0.34 10.1 0.0 2.3 2 0 0 2 2 2 0 StbA protein DHFR_1 PF00186.19 KRH94402.1 - 8.7e-22 77.5 0.3 1e-21 77.3 0.3 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Ribosomal_S4e PF00900.20 KRH94403.1 - 4.2e-22 77.8 0.2 7.6e-22 77.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KRH94403.1 - 2.6e-17 62.6 6.7 3.3e-17 62.3 4.8 2.2 2 0 0 2 2 2 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 KRH94403.1 - 1.2e-13 50.4 0.1 9.1e-13 47.6 0.0 2.2 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 KRH94403.1 - 0.002 17.8 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain KTI12 PF08433.10 KRH94404.1 - 0.0025 17.3 4.6 1.3 8.4 0.4 3.1 1 1 2 3 3 3 3 Chromatin associated protein KTI12 Cnd1 PF12717.7 KRH94405.1 - 0.00056 20.0 4.2 0.00056 20.0 4.2 6.5 4 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KRH94405.1 - 0.0013 18.9 0.1 8.8 6.9 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KRH94405.1 - 0.22 11.9 0.1 0.93 9.9 0.1 2.1 1 0 0 1 1 1 0 HEAT repeats RTP1_C1 PF10363.9 KRH94405.1 - 0.59 10.3 8.6 0.068 13.3 0.8 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DDE_3 PF13358.6 KRH94407.1 - 0.00014 21.7 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Shugoshin_N PF07558.11 KRH94409.1 - 0.069 13.0 2.4 0.12 12.3 2.4 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DDE_Tnp_IS1595 PF12762.7 KRH94410.1 - 4.4e-06 26.8 0.0 4.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain RT_RNaseH_2 PF17919.1 KRH94412.1 - 0.0028 17.7 0.7 0.004 17.2 0.2 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase CS PF04969.16 KRH94416.1 - 3.2e-11 44.1 1.4 5.8e-11 43.2 1.4 1.4 1 0 0 1 1 1 1 CS domain HTH_57 PF18679.1 KRH94416.1 - 0.014 15.7 0.2 0.045 14.1 0.1 1.9 1 1 1 2 2 2 0 ThcOx helix turn helix domain TBPIP PF07106.13 KRH94416.1 - 0.6 10.1 4.0 6.2 6.8 0.4 2.8 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain Ycf34 PF10718.9 KRH94416.1 - 0.98 10.2 3.8 0.99 10.1 0.4 2.7 3 0 0 3 3 3 0 Hypothetical chloroplast protein Ycf34 Peptidase_M1 PF01433.20 KRH94418.1 - 6e-72 241.7 11.2 5.6e-50 169.9 1.9 3.6 4 0 0 4 4 4 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KRH94418.1 - 7.8e-39 133.8 6.6 8.1e-38 130.5 6.6 2.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KRH94418.1 - 1.6e-20 73.9 0.1 7.7e-19 68.4 0.1 2.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 KRH94418.1 - 0.0021 17.5 1.7 0.0056 16.1 1.7 1.7 1 0 0 1 1 1 1 Putative aminopeptidase SprT-like PF10263.9 KRH94418.1 - 0.0061 16.4 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.6 KRH94418.1 - 0.091 12.4 0.1 8 6.1 0.1 3.0 3 0 0 3 3 3 0 Peptidase MA superfamily Trypan_PARP PF05887.11 KRH94418.1 - 0.12 12.4 6.0 0.23 11.4 6.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PIEZO PF15917.5 KRH94418.1 - 1.8 8.0 9.5 4.4 6.7 9.5 1.6 1 0 0 1 1 1 0 Piezo Ribosomal_L16 PF00252.18 KRH94419.1 - 1.5e-33 115.6 1.0 2.3e-33 115.0 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Phosphodiest PF01663.22 KRH94419.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DNA_pol_D_N PF18018.1 KRH94420.1 - 0.2 11.7 2.2 2.8 8.0 0.0 2.4 2 1 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Menin PF05053.13 KRH94420.1 - 0.93 7.8 5.2 1.3 7.3 5.2 1.1 1 0 0 1 1 1 0 Menin Ank_2 PF12796.7 KRH94422.1 - 1.9e-05 25.1 0.2 3.9e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF553 PF04473.12 KRH94422.1 - 0.034 13.7 0.2 0.048 13.2 0.2 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain Ank PF00023.30 KRH94422.1 - 0.046 14.2 0.1 0.18 12.3 0.0 2.0 2 1 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 KRH94422.1 - 0.08 13.5 0.0 0.86 10.4 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeat TFIIF_beta PF02270.15 KRH94423.1 - 7.8e-18 64.4 0.0 1.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KRH94423.1 - 9.7e-08 32.8 0.5 1.4e-06 29.0 0.5 2.5 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus RasGEF_N PF00618.20 KRH94424.1 - 0.13 12.6 7.6 0.58 10.4 0.2 4.3 3 0 0 3 3 3 0 RasGEF N-terminal motif DEAD PF00270.29 KRH94427.1 - 3.7e-34 118.0 0.2 5e-32 111.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH94427.1 - 1.1e-23 83.7 0.6 1.1e-23 83.7 0.6 2.6 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH94427.1 - 1.2e-08 35.2 8.2 3.2e-08 33.7 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KRH94427.1 - 0.0021 18.3 0.0 0.0057 16.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DUF3106 PF11304.8 KRH94427.1 - 0.014 15.8 0.7 0.21 12.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) ATP11 PF06644.11 KRH94427.1 - 0.058 13.2 1.8 0.081 12.7 0.1 2.0 2 0 0 2 2 2 0 ATP11 protein AAA_22 PF13401.6 KRH94427.1 - 0.089 13.1 0.2 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Imm8 PF15586.6 KRH94427.1 - 0.16 12.0 0.8 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 8 YolD PF08863.10 KRH94427.1 - 0.51 10.4 3.7 0.3 11.2 0.7 2.1 2 0 0 2 2 2 0 YolD-like protein TMEM208_SND2 PF05620.11 KRH94429.1 - 3.7e-13 49.6 5.8 5.1e-13 49.1 5.8 1.2 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Tic22 PF04278.12 KRH94430.1 - 0.0022 17.4 0.2 0.0036 16.7 0.2 1.3 1 0 0 1 1 1 1 Tic22-like family MIR PF02815.19 KRH94431.1 - 0.0033 17.3 5.0 0.012 15.4 0.1 2.6 1 1 1 2 2 2 2 MIR domain TetM_leader PF08076.11 KRH94432.1 - 0.21 11.4 0.8 0.4 10.5 0.8 1.4 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide AAA_12 PF13087.6 KRH94433.1 - 1e-22 80.7 0.7 4e-22 78.8 0.7 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KRH94433.1 - 2.9e-17 63.3 3.8 1.3e-14 54.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KRH94433.1 - 2e-10 40.8 6.5 0.01 15.6 0.1 4.5 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KRH94433.1 - 1.4e-08 35.2 0.0 7.3e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KRH94433.1 - 2.6e-07 30.5 0.0 2.8e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain Dna2 PF08696.11 KRH94433.1 - 5.3e-07 29.6 2.2 1e-05 25.5 1.2 2.6 2 0 0 2 2 2 1 DNA replication factor Dna2 UvrD_C_2 PF13538.6 KRH94433.1 - 6.9e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 KRH94433.1 - 0.00095 19.6 0.0 0.0027 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 KRH94433.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KRH94433.1 - 0.014 15.9 0.2 0.15 12.6 0.0 3.0 3 0 0 3 3 1 0 AAA domain AAA_22 PF13401.6 KRH94433.1 - 0.03 14.6 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KRH94433.1 - 0.049 14.1 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH94433.1 - 0.05 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KRH94433.1 - 0.098 12.8 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KRH94433.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KRH94433.1 - 0.11 13.0 1.8 0.68 10.5 0.1 3.2 3 0 0 3 3 2 0 ABC transporter cobW PF02492.19 KRH94433.1 - 0.24 11.0 2.5 0.24 11.0 0.1 2.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Glucosamine_iso PF01182.20 KRH94434.1 - 6.3e-19 68.8 0.0 1.8e-13 50.9 0.0 2.5 1 1 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PseudoU_synth_1 PF01416.20 KRH94435.1 - 1.8e-10 41.3 0.0 1.2e-08 35.3 0.0 2.9 3 0 0 3 3 3 1 tRNA pseudouridine synthase Ribosomal_S10 PF00338.22 KRH94436.1 - 2.4e-12 46.9 0.0 3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DDE_Tnp_IS1595 PF12762.7 KRH94437.1 - 1.1e-10 41.7 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.27 KRH94438.1 - 1.3e-27 96.8 0.4 1.6e-27 96.5 0.4 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dehydratase_hem PF13816.6 KRH94438.1 - 0.14 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase RT_RNaseH PF17917.1 KRH94439.1 - 1.6e-35 121.6 0.4 3.4e-35 120.5 0.1 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94439.1 - 9.2e-31 105.9 0.3 1.4e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FliW PF02623.15 KRH94439.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 FliW protein RT_RNaseH PF17917.1 KRH94441.1 - 3.3e-11 43.4 0.9 4.8e-11 42.9 0.9 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CAT_RBD PF03123.15 KRH94442.1 - 0.014 15.3 0.4 0.017 15.0 0.4 1.1 1 0 0 1 1 1 0 CAT RNA binding domain RT_RNaseH PF17917.1 KRH94443.1 - 1.5e-30 105.5 0.1 3.5e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94443.1 - 1.9e-25 88.8 0.0 3.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH94443.1 - 7.2e-05 22.8 0.1 7.2e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain DUF2883 PF11097.8 KRH94443.1 - 0.065 13.3 0.2 0.19 11.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2883) Gln-synt_N PF03951.19 KRH94444.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Corona_NS4 PF03905.13 KRH94444.1 - 0.039 14.0 1.6 0.053 13.5 0.3 1.8 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 RVT_1 PF00078.27 KRH94445.1 - 4e-28 98.5 0.9 5.4e-28 98.0 0.9 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UcrQ PF02939.16 KRH94445.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 UcrQ family eIF3g PF12353.8 KRH94446.1 - 0.00068 20.0 10.1 0.00073 19.9 3.9 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G DUF3504 PF12012.8 KRH94446.1 - 0.16 11.9 3.7 0.23 11.4 3.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3504) DA1-like PF12315.8 KRH94448.1 - 0.027 13.9 0.2 0.031 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein DA1 Imm6 PF14434.6 KRH94450.1 - 0.0091 15.9 0.3 0.012 15.5 0.3 1.2 1 0 0 1 1 1 1 Immunity protein Imm6 Dip PF17679.1 KRH94450.1 - 0.039 13.6 0.1 0.043 13.4 0.1 1.1 1 0 0 1 1 1 0 gp37/Dip protein zf-HC5HC2H_2 PF13832.6 KRH94452.1 - 8.5e-23 80.6 7.8 8.5e-23 80.6 7.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 KRH94452.1 - 4.6e-13 48.5 2.4 1.9e-12 46.5 2.4 2.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KRH94452.1 - 2.2e-12 47.0 6.4 2.2e-12 47.0 6.4 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KRH94452.1 - 7e-11 42.1 0.5 2.6e-10 40.2 0.5 2.0 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 KRH94452.1 - 1e-09 38.1 3.0 1e-09 38.1 3.0 3.7 3 1 0 3 3 3 1 PHD-finger EPL1 PF10513.9 KRH94452.1 - 0.00025 21.5 0.2 0.00025 21.5 0.2 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-PHD-like PF15446.6 KRH94452.1 - 0.0019 17.8 0.9 0.0019 17.8 0.9 2.2 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KRH94452.1 - 0.077 12.9 0.2 0.077 12.9 0.2 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1-E2_ATPase PF00122.20 KRH94453.1 - 5.3e-38 130.3 2.7 5.3e-38 130.3 2.7 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KRH94453.1 - 1.4e-27 96.6 7.2 1.4e-27 96.6 7.2 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KRH94453.1 - 6.5e-16 59.2 0.2 4.4e-15 56.5 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KRH94453.1 - 8.9e-14 51.4 0.0 2.6e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KRH94453.1 - 0.013 15.2 0.1 0.055 13.2 0.1 2.2 1 1 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KRH94453.1 - 0.019 14.7 4.8 0.061 13.0 0.1 3.5 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KRH94453.1 - 0.098 13.1 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TrbC PF04956.13 KRH94453.1 - 0.9 9.8 8.2 6.3 7.1 0.3 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family UDG PF03167.19 KRH94454.1 - 1.5e-22 80.3 0.1 7.9e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Pox_polyA_pol_N PF12630.7 KRH94455.1 - 2.9 8.3 9.0 7 7.1 0.0 3.8 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Lactamase_B_6 PF16661.5 KRH94456.1 - 6.5e-34 117.0 1.3 1.1e-33 116.3 1.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DUF1366 PF07104.11 KRH94456.1 - 0.0099 15.6 0.1 0.041 13.6 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1366) Lactamase_B_2 PF12706.7 KRH94456.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KRH94456.1 - 0.26 11.2 0.0 0.52 10.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily APG9 PF04109.16 KRH94459.1 - 6.7e-06 25.4 7.0 6.7e-06 25.4 7.0 3.2 2 1 0 2 2 2 1 Autophagy protein Apg9 PhoLip_ATPase_C PF16212.5 KRH94461.1 - 9.7e-28 97.6 44.0 9.7e-28 97.6 44.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KRH94461.1 - 2.4e-14 52.7 6.2 2.4e-14 52.7 6.2 3.9 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KRH94461.1 - 1.1e-12 48.7 0.4 4.4e-10 40.2 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KRH94461.1 - 9.4e-08 31.8 6.2 1.1e-07 31.6 0.0 3.5 3 1 1 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KRH94461.1 - 8.9e-06 25.7 0.2 0.00027 21.0 0.1 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF3671 PF12420.8 KRH94461.1 - 0.00087 19.3 5.2 0.00087 19.3 5.2 3.6 3 1 0 3 3 3 1 Protein of unknown function Hydrolase_3 PF08282.12 KRH94461.1 - 0.0097 15.7 0.1 0.0097 15.7 0.1 3.7 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase EnY2 PF10163.9 KRH94462.1 - 3.2e-07 30.6 0.1 3.7e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 NPA PF16469.5 KRH94462.1 - 0.0024 18.5 0.8 0.0036 17.9 0.8 1.3 1 1 0 1 1 1 1 Nematode polyprotein allergen ABA-1 DUF2680 PF10925.8 KRH94462.1 - 0.028 14.4 1.5 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF2014 PF09427.10 KRH94462.1 - 0.11 11.8 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) ERCC3_RAD25_C PF16203.5 KRH94463.1 - 3.5e-112 373.6 3.9 5.9e-112 372.9 3.9 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KRH94463.1 - 2.6e-31 108.4 0.0 4.6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH94463.1 - 5.1e-15 55.9 0.2 3.5e-14 53.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KRH94463.1 - 9.4e-13 48.5 0.9 7.9e-12 45.5 0.2 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KRH94463.1 - 2.2e-06 26.6 0.8 6.6e-06 25.1 0.7 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KRH94463.1 - 2.7e-05 24.0 0.1 5.6e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3638 PF12340.8 KRH94463.1 - 0.02 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) TniB PF05621.11 KRH94463.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein SPC22 PF04573.12 KRH94464.1 - 8.9e-14 51.3 1.4 1.1e-13 51.0 1.4 1.1 1 0 0 1 1 1 1 Signal peptidase subunit TruD PF01142.18 KRH94465.1 - 1.2e-61 208.8 7.1 6.7e-52 176.7 2.6 3.1 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) DUF4434 PF14488.6 KRH94465.1 - 0.0023 18.0 0.1 1.6 8.8 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4434) PPR_2 PF13041.6 KRH94465.1 - 0.03 14.5 0.2 0.27 11.5 0.1 2.5 2 0 0 2 2 2 0 PPR repeat family Sec61_beta PF03911.16 KRH94466.1 - 6.2e-05 22.9 1.9 6.2e-05 22.9 1.9 2.0 2 0 0 2 2 2 1 Sec61beta family DUF3169 PF11368.8 KRH94466.1 - 0.0056 16.2 1.5 0.0059 16.2 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) RseC_MucC PF04246.12 KRH94466.1 - 0.31 11.0 1.3 0.39 10.7 1.3 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC UPF0542 PF15086.6 KRH94466.1 - 1.8 8.6 5.3 0.58 10.1 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 Asp_protease_2 PF13650.6 KRH94473.1 - 0.0001 22.9 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH94473.1 - 0.00066 19.5 0.4 0.0013 18.5 0.4 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH94473.1 - 0.0008 19.9 0.2 0.0027 18.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 KRH94474.1 - 7.3e-11 42.3 5.6 9.2e-11 42.0 4.8 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94474.1 - 2e-06 27.7 1.4 4.9e-06 26.5 1.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Phage_pRha PF09669.10 KRH94474.1 - 0.11 13.1 0.9 5.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Polysacc_deac_1 PF01522.21 KRH94475.1 - 1.6e-07 31.2 0.1 6.1e-07 29.4 0.1 1.8 1 1 1 2 2 2 1 Polysaccharide deacetylase DUF1633 PF07794.11 KRH94475.1 - 0.016 13.4 0.0 0.02 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) CTP_synth_N PF06418.14 KRH94476.1 - 4e-44 150.9 3.8 3.4e-43 147.9 3.8 2.4 1 1 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KRH94476.1 - 1.9e-33 115.8 1.7 6.2e-20 71.8 0.1 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KRH94476.1 - 0.0046 16.7 0.0 0.49 10.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 DUF4750 PF15938.5 KRH94477.1 - 0.011 15.3 1.4 0.024 14.3 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) DUF4330 PF14221.6 KRH94477.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Cadherin_C_2 PF16492.5 KRH94477.1 - 0.11 13.3 1.6 0.21 12.4 1.6 1.6 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4212 PF13937.6 KRH94477.1 - 0.11 12.9 0.5 0.21 12.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) B12D PF06522.11 KRH94478.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Myb_DNA-binding PF00249.31 KRH94480.1 - 0.0011 19.1 0.1 0.5 10.6 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain YugN PF08868.10 KRH94480.1 - 0.088 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 YugN-like family AMP-binding PF00501.28 KRH94481.1 - 8.9e-43 146.4 0.0 5.6e-35 120.8 0.0 2.5 2 1 0 2 2 2 2 AMP-binding enzyme Renin_r PF07850.14 KRH94482.1 - 0.041 14.5 0.8 0.078 13.6 0.8 1.5 1 0 0 1 1 1 0 Renin receptor-like protein Babuvirus_MP PF07234.11 KRH94482.1 - 0.088 13.0 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein Deltameth_res PF16020.5 KRH94482.1 - 2.8 7.9 4.8 2.3 8.2 3.1 1.7 2 0 0 2 2 2 0 Deltamethrin resistance RT_RNaseH_2 PF17919.1 KRH94484.1 - 3e-28 97.8 0.1 7.6e-28 96.5 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94484.1 - 8.1e-25 87.1 0.0 2e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH94484.1 - 2.5e-21 76.2 0.1 4.9e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH94484.1 - 9.8e-17 61.3 0.1 2e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH94484.1 - 1.6e-05 24.9 0.6 1.6e-05 24.9 0.6 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KRH94485.1 - 5.7e-08 33.2 0.0 2e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KRH94485.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.6 KRH94485.1 - 0.00013 22.6 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH94485.1 - 0.00036 20.8 0.0 0.0014 18.9 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 KRH94485.1 - 0.0012 18.4 1.6 0.0025 17.4 0.2 2.2 2 0 0 2 2 2 1 Ty3 transposon peptidase Organ_specific PF10950.8 KRH94485.1 - 0.0093 16.7 1.2 0.0093 16.7 1.2 2.9 2 1 1 3 3 3 1 Organ specific protein RVP_2 PF08284.11 KRH94485.1 - 0.015 15.0 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5376 PF17346.2 KRH94485.1 - 0.041 14.2 2.6 0.77 10.1 0.1 3.1 1 1 0 2 2 2 0 Family of unknown function (DUF5376) NPL PF17800.1 KRH94485.1 - 0.068 13.7 3.8 0.1 13.2 1.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin-like domain Securin PF04856.13 KRH94486.1 - 0.0098 15.9 7.0 0.016 15.2 7.0 1.3 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor HTH_23 PF13384.6 KRH94488.1 - 0.0014 18.4 0.1 0.0027 17.4 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KRH94488.1 - 0.01 16.4 0.0 0.037 14.6 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain DUF3013 PF11217.8 KRH94488.1 - 0.03 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) FAM184 PF15665.5 KRH94488.1 - 0.038 13.8 0.2 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B UCH PF00443.29 KRH94490.1 - 0.00022 20.8 8.3 0.00027 20.5 8.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFCD_C PF12612.8 KRH94490.1 - 0.017 15.0 0.5 0.069 13.0 0.2 2.1 1 1 1 2 2 2 0 Tubulin folding cofactor D C terminal DUF3734 PF12536.8 KRH94491.1 - 0.015 15.6 0.5 2.6 8.4 0.0 2.4 2 1 0 2 2 2 0 Patatin phospholipase RT_RNaseH_2 PF17919.1 KRH94493.1 - 1.9e-31 108.0 0.0 4.5e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94493.1 - 1.4e-29 102.5 0.0 3.4e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH94493.1 - 8.9e-27 94.0 0.4 1.4e-26 93.4 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.14 KRH94493.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 PRELI-like family Helitron_like_N PF14214.6 KRH94494.1 - 1.1e-08 35.5 0.0 1.9e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KRH94495.1 - 4.8e-05 23.7 0.1 7.7e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KRH94496.1 - 1.1e-36 126.8 0.0 1.5e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KRH94496.1 - 7.9e-13 48.5 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KRH94496.1 - 8.6e-11 42.4 0.0 1.8e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KRH94496.1 - 0.00032 20.6 0.1 0.058 13.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KRH94496.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH94496.1 - 0.00098 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KRH94496.1 - 0.005 16.9 0.1 0.14 12.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KRH94496.1 - 0.011 15.3 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KRH94496.1 - 0.013 16.0 0.1 0.039 14.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KRH94496.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KRH94496.1 - 0.035 13.4 0.0 0.55 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KRH94496.1 - 0.06 13.1 1.2 1.1 8.9 0.2 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 KRH94496.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KRH94496.1 - 0.087 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KRH94496.1 - 0.1 12.0 0.5 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 KRH94496.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 KRH94496.1 - 0.14 11.5 0.2 1.2 8.5 0.2 2.2 1 1 0 1 1 1 0 Bacterial TniB protein UvrD_C_2 PF13538.6 KRH94497.1 - 1.6e-05 24.6 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KRH94497.1 - 0.00021 19.4 0.0 0.00023 19.3 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KRH94497.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF736 PF05284.12 KRH94497.1 - 0.03 14.2 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF736) DUF4988 PF16378.5 KRH94499.1 - 0.0075 16.0 0.1 0.0091 15.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF3867 PF12983.7 KRH94499.1 - 0.016 15.3 2.1 0.018 15.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) GABP-alpha PF11620.8 KRH94499.1 - 0.082 13.1 0.3 0.15 12.3 0.1 1.7 1 1 1 2 2 2 0 GA-binding protein alpha chain RVT_1 PF00078.27 KRH94500.1 - 6.6e-05 22.5 0.0 7e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH94501.1 - 9.1e-23 80.6 0.1 1.3e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94501.1 - 1e-21 76.8 0.0 1.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH94501.1 - 0.06 13.5 0.3 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Integrase zinc binding domain DDE_Tnp_IS1595 PF12762.7 KRH94504.1 - 0.00029 20.9 0.3 0.00034 20.7 0.3 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF5557 PF17712.1 KRH94504.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5557) Urm1 PF09138.11 KRH94505.1 - 2.5e-07 31.0 0.3 2.5e-07 30.9 0.3 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Yos1 PF08571.10 KRH94506.1 - 2.3e-18 66.3 1.4 2.6e-18 66.1 1.4 1.0 1 0 0 1 1 1 1 Yos1-like Ribosomal_L12 PF00542.19 KRH94506.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain SecY PF00344.20 KRH94507.1 - 2.7e-54 184.5 16.8 3.4e-54 184.2 16.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KRH94507.1 - 4.2e-16 58.5 0.3 8.4e-16 57.5 0.3 1.5 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 KRH94507.1 - 1.4 8.8 7.5 0.39 10.6 1.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) PhoU PF01895.19 KRH94508.1 - 0.21 12.0 5.4 9.2 6.8 0.1 3.2 3 0 0 3 3 3 0 PhoU domain APOBEC3 PF18771.1 KRH94508.1 - 0.25 11.5 3.2 2.4 8.3 0.0 2.6 3 0 0 3 3 3 0 APOBEC3 Formyl_trans_C PF02911.18 KRH94509.1 - 0.0021 18.3 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain GatD_N PF18195.1 KRH94509.1 - 0.0086 15.4 3.4 0.0086 15.4 3.4 1.8 2 0 0 2 2 2 1 GatD N-terminal domain GBR2_CC PF18455.1 KRH94509.1 - 0.17 12.0 0.3 0.42 10.8 0.3 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain MS_channel PF00924.18 KRH94509.1 - 0.29 10.7 3.3 7.6 6.0 0.4 2.3 1 1 2 3 3 3 0 Mechanosensitive ion channel Ada3 PF10198.9 KRH94509.1 - 3 8.0 8.8 0.25 11.5 2.4 2.4 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 DUF5096 PF17019.5 KRH94510.1 - 1.9e-28 99.6 2.1 2.7e-28 99.1 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5096) BPL_C PF02237.17 KRH94510.1 - 0.0067 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF5103 PF17116.5 KRH94510.1 - 0.17 11.1 3.0 0.055 12.7 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5103) Formyl_trans_C PF02911.18 KRH94511.1 - 0.0021 18.3 0.1 0.0038 17.5 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain GatD_N PF18195.1 KRH94511.1 - 0.0086 15.4 3.4 0.0086 15.4 3.4 1.8 2 0 0 2 2 2 1 GatD N-terminal domain GBR2_CC PF18455.1 KRH94511.1 - 0.17 12.0 0.3 0.42 10.8 0.3 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain MS_channel PF00924.18 KRH94511.1 - 0.29 10.7 3.3 7.6 6.0 0.4 2.3 1 1 2 3 3 3 0 Mechanosensitive ion channel Ada3 PF10198.9 KRH94511.1 - 3 8.0 8.8 0.25 11.5 2.4 2.4 2 1 0 2 2 2 0 Histone acetyltransferases subunit 3 Transketolase_C PF02780.20 KRH94513.1 - 6.9e-37 126.1 0.0 8.9e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KRH94513.1 - 0.002 18.4 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transket_pyr PF02779.24 KRH94514.1 - 1.2e-33 116.3 0.0 1.3e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain zf-C3HC4_3 PF13920.6 KRH94516.1 - 1.5e-09 37.6 9.7 3.5e-09 36.4 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH94516.1 - 4.3e-07 29.7 12.1 1.2e-06 28.3 12.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRH94516.1 - 8.8e-07 28.7 7.4 2e-06 27.6 7.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KRH94516.1 - 1.6e-06 28.0 9.1 1.6e-06 28.0 9.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KRH94516.1 - 2.3e-06 27.3 11.0 5e-06 26.3 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRH94516.1 - 3e-06 27.2 4.7 9.3e-06 25.6 2.3 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KRH94516.1 - 1.6e-05 25.1 9.0 3.5e-05 24.0 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KRH94516.1 - 0.00056 20.0 5.5 0.0019 18.3 5.5 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 KRH94516.1 - 0.0011 19.4 1.0 0.03 14.8 0.1 2.6 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-RING_6 PF14835.6 KRH94516.1 - 0.0016 18.2 3.3 0.0033 17.2 3.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Di19 PF05605.12 KRH94516.1 - 0.13 12.6 3.7 0.44 10.9 3.7 2.0 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 KRH94516.1 - 0.16 12.0 2.0 0.39 10.8 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KRH94516.1 - 0.24 11.5 11.1 0.091 12.9 6.4 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C2H2_4 PF13894.6 KRH94516.1 - 0.3 12.0 2.7 17 6.6 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Vpu PF00558.19 KRH94516.1 - 0.58 10.0 8.5 0.79 9.5 4.9 3.1 2 1 0 2 2 2 0 Vpu protein zf-H2C2_2 PF13465.6 KRH94516.1 - 0.99 10.0 4.0 15 6.2 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_4 PF14570.6 KRH94516.1 - 3.7 7.4 11.9 96 2.9 1.1 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1529 PF07485.11 KRH94518.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) TFIID_NTD2 PF04494.15 KRH94519.1 - 3.2e-34 118.0 8.1 6.7e-34 116.9 3.9 3.0 3 0 0 3 3 3 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 KRH94519.1 - 8.9e-28 96.0 7.6 2.9e-10 40.6 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH94519.1 - 1.1e-05 25.6 0.1 0.036 14.4 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain 14-3-3 PF00244.20 KRH94519.1 - 0.022 14.3 1.2 0.031 13.8 0.2 1.7 2 0 0 2 2 2 0 14-3-3 protein nos_propeller PF18764.1 KRH94519.1 - 0.037 13.9 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat Proteasome PF00227.26 KRH94520.1 - 2.4e-23 82.6 0.1 2.3e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit TRAM_LAG1_CLN8 PF03798.16 KRH94521.1 - 3.7e-33 115.0 32.4 5e-33 114.5 32.4 1.2 1 0 0 1 1 1 1 TLC domain CelD_N PF02927.14 KRH94522.1 - 0.057 14.3 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain TRAPP PF04051.16 KRH94523.1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glutaredoxin PF00462.24 KRH94524.1 - 6.4e-07 29.5 1.1 2.6e-06 27.5 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin DDE_Tnp_IS1595 PF12762.7 KRH94526.1 - 7.4e-20 71.5 0.4 1.1e-19 70.9 0.4 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF2179 PF10035.9 KRH94526.1 - 0.088 12.6 1.5 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) pPIWI_RE_Z PF18155.1 KRH94527.1 - 0.06 13.2 0.0 0.47 10.3 0.0 1.9 1 1 1 2 2 2 0 pPIWI RE three-gene island domain Z Tetraspanin PF00335.20 KRH94532.1 - 0.18 11.5 0.3 0.25 11.0 0.3 1.2 1 0 0 1 1 1 0 Tetraspanin family SET_assoc PF11767.8 KRH94534.1 - 0.026 14.2 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated VPS13_C PF16909.5 KRH94536.1 - 2.7e-07 30.5 0.1 3.1e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal VATC PF18716.1 KRH94539.1 - 0.17 11.8 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Vms1-associating treble clef domain ASC PF00858.24 KRH94541.1 - 0.19 10.7 0.1 0.19 10.7 0.1 2.0 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel Comm PF15957.5 KRH94541.1 - 0.21 11.9 2.9 0.22 11.9 0.2 2.0 1 1 1 2 2 2 0 Commissureless Endotoxin_M PF00555.19 KRH94542.1 - 1.1 9.3 10.3 0.027 14.5 2.3 2.0 1 1 1 2 2 2 0 delta endotoxin BBP1_N PF15271.6 KRH94543.1 - 0.11 13.3 0.4 1.4 9.7 0.4 2.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DDE_3 PF13358.6 KRH94547.1 - 4.6e-18 65.4 0.0 6.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KRH94547.1 - 2.5e-13 50.1 1.2 1.8e-12 47.3 0.3 2.2 1 1 1 2 2 2 1 Transposase PAX PF00292.18 KRH94547.1 - 2e-05 24.5 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.6 KRH94547.1 - 7.8e-05 22.6 0.0 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 KRH94547.1 - 0.0033 18.0 0.1 0.0082 16.7 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 KRH94547.1 - 0.0036 17.1 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 KRH94547.1 - 0.004 16.7 0.0 0.016 14.8 0.0 2.0 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_21 PF13276.6 KRH94547.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain HTH_3 PF01381.22 KRH94547.1 - 0.069 13.2 0.4 13 6.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix MarR_2 PF12802.7 KRH94547.1 - 0.084 12.8 0.0 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 MarR family DUF1150 PF06620.11 KRH94547.1 - 0.18 12.0 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) Gp58 PF07902.11 KRH94552.1 - 0.069 11.4 0.1 0.076 11.3 0.1 1.0 1 0 0 1 1 1 0 gp58-like protein Enolase_C PF00113.22 KRH94555.1 - 7.8e-80 268.3 0.1 1.1e-79 267.8 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KRH94555.1 - 2.2e-32 111.9 0.0 3.5e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KRH94555.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KRH94555.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DnaI_N PF07319.11 KRH94555.1 - 0.16 12.6 2.2 0.24 12.1 0.5 2.1 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus S-AdoMet_synt_C PF02773.16 KRH94556.1 - 6.9e-09 35.8 1.0 7.7e-09 35.7 1.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain Peptidase_M16 PF00675.20 KRH94558.1 - 7.4e-23 81.2 0.2 2.7e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KRH94558.1 - 0.0011 19.0 3.1 0.011 15.8 1.0 3.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain DUF4600 PF15372.6 KRH94561.1 - 0.0049 17.3 1.7 0.0059 17.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) Cnn_1N PF07989.11 KRH94561.1 - 0.0057 16.8 2.7 0.0069 16.5 2.7 1.1 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Med9 PF07544.13 KRH94561.1 - 0.0064 16.6 1.3 0.0091 16.1 1.3 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 bZIP_1 PF00170.21 KRH94561.1 - 0.014 15.5 0.7 0.019 15.0 0.7 1.2 1 0 0 1 1 1 0 bZIP transcription factor Rho_Binding PF08912.11 KRH94561.1 - 0.025 15.4 2.5 0.03 15.1 2.5 1.1 1 0 0 1 1 1 0 Rho Binding Chibby PF14645.6 KRH94561.1 - 0.043 14.2 0.4 0.053 13.9 0.3 1.3 1 1 0 1 1 1 0 Chibby family Pentapeptide_4 PF13599.6 KRH94562.1 - 1.6e-07 31.4 4.4 0.22 11.7 0.1 4.4 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) PMG PF05287.12 KRH94562.1 - 0.014 15.5 22.0 1.4 8.9 0.6 3.7 1 1 3 4 4 4 0 PMG protein Minor_capsid_1 PF10665.9 KRH94562.1 - 0.24 11.6 14.8 1.8 8.8 2.0 3.8 1 1 1 3 3 3 0 Minor capsid protein DUF5047 PF16466.5 KRH94562.1 - 1.1 9.6 9.8 6.7 7.1 1.2 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF5047) SICA_C PF12879.7 KRH94562.1 - 2.2 8.3 17.9 39 4.3 0.3 6.3 2 2 5 7 7 7 0 SICA C-terminal inner membrane domain Uteroglobin PF01099.17 KRH94563.1 - 0.1 13.0 0.0 0.11 12.9 0.0 1.0 1 0 0 1 1 1 0 Uteroglobin family S-AdoMet_synt_C PF02773.16 KRH94565.1 - 0.0026 17.7 0.8 0.56 10.2 0.5 2.9 2 0 0 2 2 2 2 S-adenosylmethionine synthetase, C-terminal domain DUF4844 PF16133.5 KRH94565.1 - 0.82 10.2 6.8 2.2 8.8 2.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) DnaJ PF00226.31 KRH94566.1 - 0.0019 18.3 0.4 0.0029 17.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain TerY_C PF15616.6 KRH94566.1 - 0.25 11.5 3.2 0.66 10.1 3.2 1.8 1 1 0 1 1 1 0 TerY-C metal binding domain Babuvirus_MP PF07234.11 KRH94567.1 - 0.014 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Movement and RNA silencing protein Herpes_LMP1 PF05297.11 KRH94567.1 - 0.015 14.5 0.2 0.017 14.4 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Caveolin PF01146.17 KRH94567.1 - 0.045 13.7 1.6 0.056 13.4 1.6 1.2 1 0 0 1 1 1 0 Caveolin DUF2852 PF11014.8 KRH94567.1 - 0.09 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) PTS_EIIC_2 PF13303.6 KRH94567.1 - 0.16 11.0 4.5 0.2 10.6 4.5 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4834 PF16118.5 KRH94567.1 - 0.78 10.7 17.8 21 6.2 17.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) RVT_1 PF00078.27 KRH94572.1 - 3.1e-08 33.4 0.1 4.2e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH94572.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RT_RNaseH PF17917.1 KRH94574.1 - 9.3e-08 32.3 0.2 1.2e-07 31.9 0.2 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Meleagrin PF08189.11 KRH94574.1 - 0.022 14.4 0.2 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Meleagrin/Cygnin family Homeobox_KN PF05920.11 KRH94576.1 - 8e-19 67.3 1.2 2e-18 66.0 1.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KRH94576.1 - 7.7e-07 28.9 0.5 2.1e-06 27.4 0.5 1.8 1 0 0 1 1 1 1 Homeodomain Glyco_hydro_46 PF01374.18 KRH94576.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 RVT_1 PF00078.27 KRH94578.1 - 3.6e-25 88.8 0.2 5.8e-25 88.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH94579.1 - 1e-23 83.6 0.1 2.2e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94579.1 - 6.9e-16 58.1 0.0 1.7e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KRH94580.1 - 3.2e-18 66.0 0.1 3.9e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 KRH94580.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3791 PF12668.7 KRH94580.1 - 0.068 13.2 0.5 7.2 6.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) Retrotrans_gag PF03732.17 KRH94584.1 - 0.035 14.4 0.2 0.065 13.5 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 KRH94585.1 - 7e-28 97.7 0.7 1.3e-27 96.8 0.7 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KRH94585.1 - 1.7e-05 24.8 0.1 8.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 KRH94585.1 - 0.0021 17.9 0.0 0.0064 16.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Integrase_H2C2 PF17921.1 KRH94586.1 - 1.7e-05 24.8 1.5 5.7e-05 23.2 1.5 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KRH94586.1 - 0.0076 16.5 0.2 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Cullin_Nedd8 PF10557.9 KRH94590.1 - 0.021 14.9 0.7 0.051 13.6 0.2 1.8 2 0 0 2 2 2 0 Cullin protein neddylation domain Metallophos PF00149.28 KRH94592.1 - 6.6e-34 118.2 0.1 9.3e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ANAPC4_WD40 PF12894.7 KRH94593.1 - 6.4e-07 29.6 0.1 0.037 14.3 0.0 4.8 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KRH94593.1 - 0.0034 18.2 0.0 0.63 11.0 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Kelch_6 PF13964.6 KRH94593.1 - 0.026 14.8 0.0 0.14 12.5 0.0 2.3 1 0 0 1 1 1 0 Kelch motif A_thal_3526 PF09713.10 KRH94594.1 - 0.0084 16.3 0.1 0.038 14.2 0.1 2.2 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) ORMDL PF04061.14 KRH94595.1 - 4.3e-32 110.8 7.7 4.8e-32 110.6 7.7 1.0 1 0 0 1 1 1 1 ORMDL family TonB_2 PF13103.6 KRH94596.1 - 0.098 12.9 0.2 0.22 11.8 0.2 1.5 1 0 0 1 1 1 0 TonB C terminal Cullin_Nedd8 PF10557.9 KRH94598.1 - 0.0007 19.6 2.6 0.005 16.9 0.2 3.4 2 1 0 2 2 2 1 Cullin protein neddylation domain HhH-GPD PF00730.25 KRH94601.1 - 3.4e-15 56.4 0.0 4.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PSI_integrin PF17205.3 KRH94601.1 - 0.045 13.5 1.8 0.081 12.7 1.8 1.4 1 0 0 1 1 1 0 Integrin plexin domain ArAE_1_C PF11728.8 KRH94601.1 - 0.046 13.7 0.5 0.083 12.9 0.1 1.6 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Acyltransf_C PF16076.5 KRH94601.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase C-terminus EndIII_4Fe-2S PF10576.9 KRH94601.1 - 0.64 10.4 6.9 1.6 9.1 6.9 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III SBBP PF06739.11 KRH94602.1 - 0.42 10.7 2.9 47 4.1 0.1 3.4 3 0 0 3 3 3 0 Beta-propeller repeat TBCA PF02970.16 KRH94603.1 - 3.9e-05 23.9 10.0 4.9e-05 23.6 10.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spectrin PF00435.21 KRH94603.1 - 0.015 15.8 8.7 0.45 11.0 0.7 2.0 1 1 0 2 2 2 0 Spectrin repeat DUF1515 PF07439.11 KRH94603.1 - 0.017 15.2 0.8 0.02 14.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1647 PF07801.11 KRH94603.1 - 0.018 14.8 1.7 0.021 14.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Val_tRNA-synt_C PF10458.9 KRH94603.1 - 0.021 15.1 5.2 0.36 11.2 0.4 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DHR10 PF18595.1 KRH94603.1 - 0.037 14.1 10.5 0.05 13.7 10.5 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 KRH94603.1 - 0.042 13.8 14.2 0.068 13.1 4.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit ACCA PF03255.14 KRH94603.1 - 0.06 13.2 4.7 0.081 12.8 4.7 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit XisI PF08869.11 KRH94603.1 - 0.091 13.1 7.5 0.37 11.2 6.8 1.8 1 1 1 2 2 2 0 XisI protein Sec34 PF04136.15 KRH94603.1 - 0.1 12.4 7.7 0.13 12.2 7.7 1.1 1 0 0 1 1 1 0 Sec34-like family DUF4407 PF14362.6 KRH94603.1 - 0.11 11.8 5.4 0.14 11.5 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KRH94603.1 - 0.14 10.0 6.9 0.17 9.8 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCAP PF11105.8 KRH94603.1 - 0.18 11.7 2.3 0.48 10.4 2.3 1.7 1 1 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a ISG65-75 PF11727.8 KRH94603.1 - 0.25 10.5 7.0 0.28 10.4 7.0 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Csm1_N PF18504.1 KRH94603.1 - 0.56 10.6 10.8 1.7 9.0 0.8 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 KRH94603.1 - 0.64 9.2 7.1 0.7 9.1 7.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein Bap31_Bap29_C PF18035.1 KRH94603.1 - 0.89 9.6 11.8 0.42 10.7 1.5 2.5 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain eIF-4B PF06273.11 KRH94603.1 - 1.7 7.7 5.5 1.8 7.5 5.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Vir_act_alpha_C PF10400.9 KRH94603.1 - 8.6 7.1 8.1 7.1 7.4 2.6 2.0 1 1 1 2 2 2 0 Virulence activator alpha C-term DRMBL PF07522.14 KRH94605.1 - 5.1e-21 74.9 1.6 1.3e-20 73.6 0.5 2.2 1 1 1 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KRH94605.1 - 7.5e-05 22.8 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KRH94605.1 - 0.00049 19.7 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CoaE PF01121.20 KRH94607.1 - 2.5e-23 82.6 0.0 3.1e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KRH94607.1 - 5.9e-07 30.1 1.8 2.5e-06 28.1 1.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KRH94607.1 - 0.0031 17.8 0.5 0.17 12.1 0.5 2.2 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KRH94607.1 - 0.014 15.3 1.3 0.029 14.2 1.3 1.7 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 KRH94607.1 - 0.016 15.4 0.0 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KRH94607.1 - 0.045 14.3 1.2 0.072 13.6 1.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KRH94607.1 - 0.048 14.1 0.2 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KRH94607.1 - 0.075 13.2 0.2 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.6 KRH94607.1 - 0.13 12.4 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family DUF5499 PF17603.2 KRH94614.1 - 0.031 14.9 0.5 0.043 14.4 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5499) RVT_1 PF00078.27 KRH94615.1 - 5.8e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UxuA PF03786.13 KRH94616.1 - 0.062 12.1 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) MDFI PF15316.6 KRH94618.1 - 0.018 15.2 1.4 0.018 15.2 1.4 1.8 2 0 0 2 2 2 0 MyoD family inhibitor Ribosomal_S6e PF01092.19 KRH94619.1 - 2.7e-36 124.3 0.0 5.8e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e RhoGAP PF00620.27 KRH94620.1 - 1.2e-19 70.6 0.3 2.1e-19 69.9 0.3 1.4 1 0 0 1 1 1 1 RhoGAP domain RAI16-like PF10257.9 KRH94620.1 - 0.05 12.5 0.2 0.069 12.0 0.2 1.2 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein PseudoU_synth_2 PF00849.22 KRH94621.1 - 5.4e-30 104.6 0.1 8.2e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Baculo_p74_N PF08404.10 KRH94621.1 - 0.0017 17.5 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal S4 PF01479.25 KRH94621.1 - 0.006 16.3 0.2 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 S4 domain Acyl_CoA_thio PF02551.15 KRH94621.1 - 0.16 11.8 0.3 0.6 10.0 0.1 1.9 2 0 0 2 2 2 0 Acyl-CoA thioesterase POT1 PF02765.17 KRH94622.1 - 4.4e-07 29.8 3.2 1e-06 28.6 0.8 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KRH94622.1 - 0.00023 21.1 0.3 2.1 8.4 0.1 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Vps16_C PF04840.12 KRH94623.1 - 1.8e-05 23.9 1.4 1.8e-05 23.9 1.4 2.1 2 0 0 2 2 2 1 Vps16, C-terminal region Ham1p_like PF01725.16 KRH94624.1 - 8.6e-26 91.0 0.0 9.8e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family iPGM_N PF06415.13 KRH94625.1 - 1.4e-28 99.9 0.6 2e-28 99.4 0.6 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KRH94625.1 - 9.3e-12 44.8 0.1 1e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Chitin_synth_1 PF01644.17 KRH94625.1 - 0.1 12.6 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Chitin synthase Mon2_C PF16206.5 KRH94629.1 - 0.062 11.4 0.1 0.064 11.4 0.1 1.0 1 0 0 1 1 1 0 C-terminal region of Mon2 protein RT_RNaseH_2 PF17919.1 KRH94630.1 - 9.5e-21 73.7 0.0 1e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KRH94630.1 - 3.3e-15 56.3 0.0 3.6e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase XRN1_D1 PF18332.1 KRH94631.1 - 0.0036 17.1 0.1 0.0051 16.6 0.1 1.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain ABC_tran PF00005.27 KRH94634.1 - 1.2e-29 103.6 1.5 4.6e-15 56.3 0.0 3.4 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 KRH94634.1 - 6.5e-11 42.6 7.2 0.014 15.3 0.1 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KRH94634.1 - 5.6e-09 36.6 0.0 6.5e-05 23.4 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KRH94634.1 - 1.8e-07 30.8 11.1 0.011 15.2 0.2 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 KRH94634.1 - 2.1e-07 30.7 3.7 2.1e-07 30.7 3.7 3.4 4 0 0 4 4 3 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 KRH94634.1 - 4.5e-07 29.4 3.2 4.5e-07 29.4 3.2 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.6 KRH94634.1 - 1.9e-06 27.9 25.2 0.05 13.3 4.4 4.0 1 1 2 3 3 3 2 AAA ATPase domain Fer4_6 PF12837.7 KRH94634.1 - 2.1e-06 27.6 12.0 8.1e-05 22.5 2.3 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_22 PF13401.6 KRH94634.1 - 1.3e-05 25.5 0.3 0.042 14.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 KRH94634.1 - 1.3e-05 24.6 1.5 0.0079 15.4 0.1 2.3 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KRH94634.1 - 1.6e-05 24.9 1.5 0.077 12.9 0.1 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KRH94634.1 - 2.2e-05 24.1 0.2 0.14 11.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KRH94634.1 - 5.5e-05 23.1 0.7 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KRH94634.1 - 5.5e-05 23.7 0.7 0.08 13.5 0.1 2.9 2 0 0 2 2 2 1 AAA domain VirE PF05272.11 KRH94634.1 - 0.00012 21.8 0.8 0.47 10.1 0.1 2.8 2 1 0 2 2 2 2 Virulence-associated protein E AAA_24 PF13479.6 KRH94634.1 - 0.0002 21.2 0.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Fer4_21 PF14697.6 KRH94634.1 - 0.00028 21.0 11.8 0.00069 19.7 11.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.15 KRH94634.1 - 0.00029 20.8 0.5 0.007 16.3 0.1 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 KRH94634.1 - 0.00047 20.6 0.1 0.19 12.1 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KRH94634.1 - 0.00054 19.2 0.2 0.061 12.5 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_10 PF13237.6 KRH94634.1 - 0.00063 19.8 14.3 0.0032 17.5 1.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.22 KRH94634.1 - 0.00073 19.9 0.4 2.3 8.7 0.0 2.9 2 1 0 2 2 2 2 RNA helicase Fer4_7 PF12838.7 KRH94634.1 - 0.00086 19.8 22.0 0.003 18.1 1.3 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KRH94634.1 - 0.00094 19.3 13.5 0.0021 18.2 13.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 KRH94634.1 - 0.0034 17.0 0.6 2.2 7.9 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KRH94634.1 - 0.0035 17.3 0.8 0.76 9.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KRH94634.1 - 0.0073 16.1 0.1 0.73 9.6 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Fer4_16 PF13484.6 KRH94634.1 - 0.0075 17.2 0.2 0.0075 17.2 0.2 3.2 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain TsaE PF02367.17 KRH94634.1 - 0.008 16.2 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_2 PF12797.7 KRH94634.1 - 0.016 15.2 1.3 0.016 15.2 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_28 PF13521.6 KRH94634.1 - 0.026 14.8 0.1 0.52 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KRH94634.1 - 0.026 15.0 2.0 0.026 15.0 2.0 3.7 1 1 2 4 4 4 0 AAA domain PRK PF00485.18 KRH94634.1 - 0.031 14.0 0.3 0.76 9.5 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 KRH94634.1 - 0.035 14.1 6.1 2.4 8.2 0.1 3.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KRH94634.1 - 0.04 14.0 1.3 12 6.0 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KRH94634.1 - 0.059 13.5 0.1 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain HEXIM PF15313.6 KRH94634.1 - 0.08 13.1 3.2 0.19 11.9 3.2 1.6 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein AAA_30 PF13604.6 KRH94634.1 - 0.081 12.6 0.0 16 5.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 KRH94634.1 - 0.087 13.0 0.8 2.1 8.6 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DnaB_C PF03796.15 KRH94634.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 KRH94634.1 - 0.11 12.0 0.7 14 5.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KRH94634.1 - 0.12 12.0 0.7 6.9 6.3 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase cobW PF02492.19 KRH94634.1 - 0.12 11.9 4.8 0.51 9.9 0.0 3.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain HHH_5 PF14520.6 KRH94634.1 - 0.15 12.7 0.6 1 10.0 0.1 2.5 2 0 0 2 2 1 0 Helix-hairpin-helix domain AAA_19 PF13245.6 KRH94634.1 - 0.16 12.3 0.7 20 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Fer4_4 PF12800.7 KRH94634.1 - 0.22 12.1 12.1 0.062 13.8 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 KRH94634.1 - 0.26 11.2 4.4 11 5.9 0.3 3.5 2 2 1 3 3 3 0 NTPase PduV-EutP PF10662.9 KRH94634.1 - 0.27 11.0 2.9 1.5 8.6 0.2 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 KRH94634.1 - 0.29 10.9 3.6 0.6 9.9 0.4 2.8 3 1 0 3 3 2 0 MukB N-terminal Fer4_3 PF12798.7 KRH94634.1 - 0.33 12.0 13.5 0.12 13.4 3.1 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KRH94634.1 - 2.4 8.7 12.3 34 5.1 12.5 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L28e PF01778.17 KRH94635.1 - 5.3e-26 91.6 0.1 1.4e-25 90.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family AAA_15 PF13175.6 KRH94635.1 - 0.027 14.2 11.7 0.03 14.0 11.7 1.2 1 0 0 1 1 1 0 AAA ATPase domain Mak16 PF04874.14 KRH94635.1 - 0.1 13.2 12.9 0.25 12.0 12.9 1.6 1 0 0 1 1 1 0 Mak16 protein C-terminal region AAA_12 PF13087.6 KRH94636.1 - 4.4e-59 199.5 2.7 1.6e-58 197.7 2.7 2.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KRH94636.1 - 7.3e-54 183.3 8.3 1.3e-27 97.2 0.4 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 KRH94636.1 - 5.4e-10 39.3 0.0 2.4e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KRH94636.1 - 4.7e-09 36.7 0.0 1.4e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KRH94636.1 - 0.00016 21.7 0.2 0.0008 19.4 0.2 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rpo132 PF12415.8 KRH94636.1 - 0.15 11.4 2.6 0.22 10.8 1.1 2.1 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase VTC PF09359.10 KRH94638.1 - 3.4e-57 193.9 28.2 3.4e-57 193.9 28.2 4.4 4 1 0 4 4 4 1 VTC domain DUF202 PF02656.15 KRH94638.1 - 6.1e-13 49.0 2.9 1.4e-12 47.9 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) LSM PF01423.22 KRH94639.1 - 1.6e-07 30.9 0.1 1.4e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 LSM domain Sigma_reg_N PF13800.6 KRH94640.1 - 0.0069 16.6 0.8 0.042 14.2 0.8 2.3 1 0 0 1 1 1 1 Sigma factor regulator N-terminal DMPK_coil PF08826.10 KRH94640.1 - 0.64 10.2 6.5 0.53 10.4 3.2 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like SGS PF05002.15 KRH94641.1 - 5e-07 29.7 9.5 2.5e-06 27.5 9.5 1.9 1 1 0 1 1 1 1 SGS domain NusB PF01029.18 KRH94641.1 - 0.29 11.4 4.0 0.39 10.9 4.0 1.3 1 0 0 1 1 1 0 NusB family ANAPC2 PF08672.11 KRH94641.1 - 0.34 11.4 4.9 3.8 8.1 0.9 2.6 1 1 1 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Peptidase_S46 PF10459.9 KRH94641.1 - 0.7 8.5 6.5 0.76 8.4 6.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3298 PF11738.8 KRH94641.1 - 1.8 9.6 4.8 0.74 10.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3298) PhaC_N PF07167.13 KRH94642.1 - 1.4 8.5 5.0 55 3.3 0.1 3.6 2 2 1 4 4 4 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Methyltransf_11 PF08241.12 KRH94643.1 - 7e-12 45.8 0.0 2.2e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KRH94643.1 - 1.3e-08 34.9 0.0 6.4e-07 29.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRH94643.1 - 3.1e-08 34.2 0.0 1.1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH94643.1 - 9.7e-08 32.0 1.0 5.6e-05 23.0 0.2 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KRH94643.1 - 1.4e-05 25.8 0.2 0.00014 22.5 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KRH94643.1 - 1.4e-05 24.6 0.0 7.9e-05 22.1 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KRH94643.1 - 0.026 13.4 0.0 0.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DUF4118 PF13493.6 KRH94644.1 - 0.21 11.4 0.2 0.25 11.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) HlyIII PF03006.20 KRH94645.1 - 4.6e-15 55.9 13.4 1.6e-07 31.3 6.3 2.1 2 0 0 2 2 2 2 Haemolysin-III related Peptidase_S10 PF00450.22 KRH94645.1 - 0.094 12.1 1.2 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase HigB_toxin PF09907.9 KRH94646.1 - 0.0043 17.2 2.1 0.011 15.9 2.0 1.7 1 1 0 1 1 1 1 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system DASH_Duo1 PF08651.10 KRH94646.1 - 0.01 15.6 0.8 0.018 14.8 0.5 1.4 1 1 0 1 1 1 0 DASH complex subunit Duo1 Med30 PF11315.8 KRH94646.1 - 0.015 15.5 1.4 0.016 15.4 1.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 Laminin_II PF06009.12 KRH94646.1 - 0.022 14.8 2.0 0.026 14.6 2.0 1.1 1 0 0 1 1 1 0 Laminin Domain II PilO PF04350.13 KRH94646.1 - 0.029 14.5 1.0 0.036 14.2 0.9 1.3 1 1 0 1 1 1 0 Pilus assembly protein, PilO BsuBI_PstI_RE PF06616.11 KRH94646.1 - 0.036 13.3 0.3 0.04 13.2 0.3 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Muted PF14942.6 KRH94646.1 - 0.044 14.1 3.3 0.053 13.9 3.3 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein V-SNARE_C PF12352.8 KRH94646.1 - 0.26 11.6 1.7 1.4 9.2 0.3 2.3 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus XhlA PF10779.9 KRH94646.1 - 0.32 11.2 3.2 0.45 10.8 2.8 1.6 1 1 0 1 1 1 0 Haemolysin XhlA DUF948 PF06103.11 KRH94646.1 - 0.65 10.3 3.7 1.7 8.9 3.7 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DASH_Dam1 PF08653.10 KRH94646.1 - 0.95 9.3 6.8 1 9.2 0.5 2.5 2 1 1 3 3 3 0 DASH complex subunit Dam1 BAH PF01426.18 KRH94647.1 - 0.084 12.7 0.1 0.093 12.6 0.1 1.0 1 0 0 1 1 1 0 BAH domain Peptidase_C48 PF02902.19 KRH94648.1 - 5.8e-13 49.2 3.9 5.8e-13 49.2 3.9 1.7 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF2834 PF11196.8 KRH94648.1 - 0.24 11.8 1.3 0.83 10.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) GCIP PF13324.6 KRH94649.1 - 0.012 15.3 1.0 0.032 13.8 1.0 1.7 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pkinase PF00069.25 KRH94651.1 - 2.5e-49 168.0 0.5 1.4e-48 165.6 0.5 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH94651.1 - 2.6e-19 69.5 0.0 1e-15 57.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRH94651.1 - 5.6e-05 22.1 0.0 8.1e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KRH94651.1 - 0.0019 18.2 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KRH94651.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KRH94651.1 - 0.02 14.5 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Thioredoxin_2 PF13098.6 KRH94651.1 - 0.099 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain tRNA-synt_1c PF00749.21 KRH94652.1 - 1.7e-73 247.3 1.0 3.6e-73 246.2 1.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KRH94652.1 - 1.1e-21 77.5 0.6 2.7e-21 76.2 0.6 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KRH94652.1 - 0.009 15.4 1.3 0.022 14.1 1.3 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF4525 PF15027.6 KRH94652.1 - 0.087 12.6 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) BRCA-2_OB1 PF09103.10 KRH94652.1 - 0.14 12.2 0.5 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 CDC37_N PF03234.14 KRH94654.1 - 1.6e-08 35.5 3.1 1.6e-08 35.5 3.1 1.5 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding DUF4670 PF15709.5 KRH94654.1 - 0.031 13.6 11.3 0.042 13.2 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) WD40 PF00400.32 KRH94655.1 - 6.6e-08 33.1 2.7 0.034 15.0 0.4 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat CTP-dep_RFKase PF01982.16 KRH94656.1 - 0.012 15.7 0.7 0.057 13.5 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF120 DUF2856 PF11043.8 KRH94656.1 - 0.046 13.8 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) FlhC PF05280.11 KRH94656.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) IL31 PF15209.6 KRH94656.1 - 0.054 13.3 0.2 0.054 13.3 0.2 3.8 4 1 1 5 5 5 0 Interleukin 31 AsiA PF09010.10 KRH94656.1 - 0.4 10.8 3.7 1.1 9.4 1.2 2.6 2 0 0 2 2 2 0 Anti-Sigma Factor A Myosin_head PF00063.21 KRH94657.1 - 7.3e-236 784.6 16.8 7.3e-236 784.6 16.8 4.0 2 1 2 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.19 KRH94657.1 - 9e-08 31.8 2.2 2.1e-07 30.6 1.6 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain APG6_N PF17675.1 KRH94657.1 - 0.0015 19.1 21.5 0.0015 19.1 21.5 10.5 2 2 7 9 9 9 2 Apg6 coiled-coil region AAA_22 PF13401.6 KRH94657.1 - 0.13 12.6 0.0 0.13 12.6 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 KRH94657.1 - 0.92 9.9 4.8 3.2 8.1 0.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain E1_dh PF00676.20 KRH94660.1 - 2.8e-63 213.7 0.0 3.3e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KRH94660.1 - 3e-05 23.9 0.1 5.2e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain adh_short PF00106.25 KRH94661.1 - 5.5e-16 58.6 0.4 4e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KRH94661.1 - 8e-05 22.3 0.0 0.39 10.2 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 KRH94661.1 - 0.0035 17.1 0.0 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Y2_Tnp PF04986.13 KRH94661.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative transposase NTase_sub_bind PF08780.11 KRH94661.1 - 0.14 12.1 1.8 0.65 10.0 0.3 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like KR PF08659.10 KRH94661.1 - 0.25 11.2 0.8 1.5 8.7 0.2 2.5 2 1 0 2 2 2 0 KR domain PTR2 PF00854.21 KRH94662.1 - 4.5e-68 229.9 20.9 2.4e-36 125.4 4.5 2.2 2 0 0 2 2 2 2 POT family MFS_1 PF07690.16 KRH94662.1 - 6.8e-13 48.3 21.7 1.4e-10 40.7 13.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KRH94662.1 - 1.5 7.1 5.1 0.18 10.1 0.8 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector PRK PF00485.18 KRH94663.1 - 4.4e-07 29.9 0.1 7.1e-05 22.6 0.0 2.8 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KRH94663.1 - 1.9e-06 28.1 0.0 4.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KRH94663.1 - 0.00018 21.1 0.0 0.009 15.5 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KRH94663.1 - 0.00021 21.8 0.0 0.00088 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KRH94663.1 - 0.00093 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KRH94663.1 - 0.0021 18.4 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KRH94663.1 - 0.0027 17.4 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH94663.1 - 0.0037 17.2 0.1 0.0065 16.4 0.1 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KRH94663.1 - 0.0047 17.0 2.4 0.01 15.8 0.0 2.8 3 2 1 4 4 4 1 AAA domain ATP_bind_1 PF03029.17 KRH94663.1 - 0.0062 16.4 0.1 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 KRH94663.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_7 PF12775.7 KRH94663.1 - 0.0071 15.9 0.1 0.039 13.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region Chlorophyllase PF07224.11 KRH94663.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase AAA_22 PF13401.6 KRH94663.1 - 0.045 14.0 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KRH94663.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KRH94663.1 - 0.095 12.7 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KRH94663.1 - 0.1 13.1 0.1 0.84 10.2 0.0 2.3 2 2 0 2 2 2 0 ABC transporter zinc_ribbon_12 PF11331.8 KRH94663.1 - 0.1 12.4 4.0 0.21 11.4 2.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain AAA_28 PF13521.6 KRH94663.1 - 0.15 12.3 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Trehalose_PPase PF02358.16 KRH94664.1 - 2.1e-28 99.0 0.1 7.4e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase S6PP PF05116.13 KRH94664.1 - 0.0039 16.8 0.0 0.64 9.5 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase DUF3800 PF12686.7 KRH94664.1 - 0.026 15.2 0.0 0.026 15.2 0.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Glyco_transf_20 PF00982.21 KRH94665.1 - 2.7e-18 65.9 0.2 3.2e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 RPN7 PF10602.9 KRH94666.1 - 4.8e-30 104.5 3.4 9.4e-30 103.6 3.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KRH94666.1 - 5.5e-10 39.7 2.0 1.4e-09 38.3 2.0 1.8 1 0 0 1 1 1 1 PCI domain RRM_1 PF00076.22 KRH94667.1 - 0.00016 21.4 2.1 0.35 10.7 0.2 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KRH94667.1 - 0.0095 16.0 1.8 0.015 15.3 0.4 2.1 2 0 0 2 2 2 1 RNA binding motif WD40 PF00400.32 KRH94668.1 - 1.1e-12 48.2 5.3 7.1e-06 26.7 1.8 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat TSC22 PF01166.18 KRH94669.1 - 0.027 14.8 3.7 0.027 14.8 3.7 7.4 3 3 4 8 8 8 0 TSC-22/dip/bun family DUF3113 PF11310.8 KRH94669.1 - 0.088 12.8 4.9 0.45 10.5 2.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) S10_plectin PF03501.15 KRH94670.1 - 1.1e-24 86.3 0.0 1.3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain GCS PF03074.16 KRH94672.1 - 3.5e-29 102.3 1.4 3.7e-29 102.2 1.4 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF243 PF03103.17 KRH94674.1 - 0.017 15.5 0.2 0.044 14.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF243) Spo0A_C PF08769.11 KRH94674.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DDE_Tnp_IS1595 PF12762.7 KRH94676.1 - 5.2e-19 68.8 0.1 7.5e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF2179 PF10035.9 KRH94676.1 - 2.7 7.8 5.3 0.83 9.4 0.7 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) PUF PF00806.19 KRH94677.1 - 0.035 13.8 1.6 0.045 13.5 0.4 1.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat zf-C4_Topoisom PF01396.19 KRH94677.1 - 0.044 13.6 3.5 0.13 12.1 3.5 1.8 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-LITAF-like PF10601.9 KRH94677.1 - 0.045 14.0 1.5 0.11 12.8 1.5 1.6 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain COX7C PF02935.16 KRH94677.1 - 0.052 13.8 0.2 0.084 13.1 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc GDI PF00996.18 KRH94679.1 - 4e-07 28.9 0.5 8.4e-06 24.6 0.2 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor SCA7 PF08313.12 KRH94680.1 - 1.1e-13 50.8 1.0 2.6e-13 49.6 1.0 1.6 1 0 0 1 1 1 1 SCA7, zinc-binding domain Ku_PK_bind PF08785.11 KRH94680.1 - 0.0003 20.9 0.5 0.00045 20.4 0.5 1.2 1 0 0 1 1 1 1 Ku C terminal domain like DUF4822 PF16103.5 KRH94681.1 - 0.032 14.5 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4822) CBFD_NFYB_HMF PF00808.23 KRH94684.1 - 1.4e-20 73.3 1.6 2e-20 72.8 1.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRH94684.1 - 0.0012 19.3 0.1 0.0017 18.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KRH94684.1 - 0.019 15.0 0.1 0.034 14.2 0.1 1.4 1 1 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KRH94684.1 - 0.03 14.4 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold LepB_N PF18640.1 KRH94684.1 - 0.07 12.7 3.6 0.28 10.8 0.4 2.1 1 1 1 2 2 2 0 LepB N-terminal domain Pkinase PF00069.25 KRH94685.1 - 9.8e-47 159.5 2.0 1e-46 159.4 0.7 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH94685.1 - 3.6e-25 88.7 0.0 6.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH94685.1 - 6.1e-10 38.9 0.9 4.7e-09 36.0 0.1 2.4 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KRH94685.1 - 0.00055 19.3 2.0 0.0041 16.5 0.0 2.8 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KRH94685.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_D PF01813.17 KRH94686.1 - 4.6e-52 176.7 3.6 5.3e-52 176.5 3.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D Mucin_bdg PF03272.13 KRH94686.1 - 0.08 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module WD40 PF00400.32 KRH94687.1 - 5.7e-08 33.3 3.6 0.023 15.6 0.4 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KRH94687.1 - 0.0052 17.0 0.3 2.8 8.3 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5089 PF17002.5 KRH94688.1 - 2.9e-49 167.6 30.5 2.9e-49 167.6 30.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) Sec20 PF03908.13 KRH94688.1 - 5.7 6.9 9.4 2.3 8.2 1.1 2.7 2 1 0 2 2 2 0 Sec20 Sec1 PF00995.23 KRH94689.1 - 4e-07 29.7 14.4 0.0015 17.9 5.4 2.2 1 1 1 2 2 2 2 Sec1 family Cofilin_ADF PF00241.20 KRH94690.1 - 2.4e-14 53.2 0.3 3.2e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pepsin-I3 PF06394.13 KRH94691.1 - 0.095 12.9 0.8 0.17 12.1 0.4 1.6 1 1 1 2 2 2 0 Pepsin inhibitor-3-like repeated domain Pox_MCEL PF03291.16 KRH94692.1 - 5.9e-54 183.4 9.0 7.6e-54 183.1 9.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KRH94692.1 - 4.1e-12 46.6 0.0 7.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH94692.1 - 1.9e-11 44.0 0.2 2.7e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KRH94692.1 - 7.8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KRH94692.1 - 2.6e-09 37.6 0.0 6.8e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KRH94692.1 - 3e-08 34.3 0.0 5.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KRH94692.1 - 4.3e-05 22.9 0.1 6.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KRH94692.1 - 0.00014 21.3 0.8 0.00023 20.6 0.8 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 KRH94692.1 - 0.00036 20.2 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KRH94692.1 - 0.00059 19.2 1.1 0.00091 18.6 1.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KRH94692.1 - 0.00087 19.3 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KRH94692.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KRH94692.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KRH94692.1 - 0.04 12.8 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 KRH94692.1 - 0.056 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ribosom_S12_S23 PF00164.25 KRH94694.1 - 2.3e-32 111.0 0.8 2.5e-32 110.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 TPR_14 PF13428.6 KRH94695.1 - 0.0073 17.0 0.7 3.1 8.9 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KRH94695.1 - 0.029 14.7 5.0 13 6.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KRH94695.1 - 0.031 14.5 17.9 3.4 8.1 0.4 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KRH94695.1 - 0.036 14.2 24.5 0.81 10.0 0.3 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat UBX PF00789.20 KRH94695.1 - 0.079 13.2 0.8 4.5 7.6 0.1 2.7 2 0 0 2 2 2 0 UBX domain TPR_10 PF13374.6 KRH94695.1 - 0.21 11.5 1.0 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KRH94695.1 - 0.28 11.3 1.9 29 5.0 0.0 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KRH94695.1 - 0.59 10.0 23.2 1.8 8.5 0.5 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KRH94695.1 - 0.77 9.8 20.2 1.5 8.9 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Linker_histone PF00538.19 KRH94695.1 - 4.3 7.8 6.7 16 5.9 0.0 4.1 4 1 1 5 5 5 0 linker histone H1 and H5 family NifU_N PF01592.16 KRH94696.1 - 2.8e-53 179.5 0.1 3.2e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Med6 PF04934.14 KRH94697.1 - 8.9e-25 87.0 2.1 1.2e-24 86.6 2.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DEAD PF00270.29 KRH94698.1 - 4.9e-33 114.4 0.6 1e-32 113.3 0.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KRH94698.1 - 1.2e-27 96.4 2.3 6.3e-27 94.1 0.1 2.9 2 1 2 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KRH94698.1 - 6.6e-11 42.5 1.1 6.6e-11 42.5 1.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KRH94698.1 - 0.00011 21.9 2.9 0.00025 20.7 2.9 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 KRH94698.1 - 0.0024 18.2 0.0 0.0062 16.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KRH94698.1 - 0.046 13.7 0.6 0.19 11.7 0.0 2.2 3 0 0 3 3 3 0 Flavivirus DEAD domain AAA PF00004.29 KRH94698.1 - 0.077 13.4 0.4 0.23 11.9 0.4 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KRH94698.1 - 0.34 11.2 1.5 4.9 7.4 1.5 2.5 1 1 0 1 1 1 0 AAA domain Rep_fac-A_C PF08646.10 KRH94700.1 - 3.2e-38 130.8 12.8 2.8e-37 127.7 6.2 2.9 3 0 0 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KRH94700.1 - 4.4e-18 65.0 1.2 4.7e-17 61.7 0.2 2.6 2 1 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KRH94700.1 - 1.9e-12 47.0 1.6 3.6e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KRH94700.1 - 5.1e-08 32.9 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 KRH94700.1 - 3.7 7.2 9.9 9.2 5.9 0.1 3.1 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 3 MCM PF00493.23 KRH94701.1 - 2.4e-94 314.7 0.1 3.5e-94 314.1 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH94701.1 - 4.7e-38 129.9 0.0 9.4e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRH94701.1 - 3e-24 85.2 1.7 3.3e-24 85.1 0.3 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KRH94701.1 - 1.5e-12 48.0 0.8 1.5e-12 48.0 0.8 3.1 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 KRH94701.1 - 7.3e-12 45.1 0.5 1.2e-08 34.6 0.1 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KRH94701.1 - 3.9e-07 30.0 0.0 8.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH94701.1 - 4.2e-06 26.8 0.0 9.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KRH94701.1 - 0.0016 18.9 1.0 0.009 16.4 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KRH94701.1 - 0.0019 17.9 0.0 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KRH94701.1 - 0.015 15.6 0.2 0.3 11.4 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KRH94701.1 - 0.048 13.4 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain TAF6_C PF07571.13 KRH94702.1 - 5.3e-17 61.9 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KRH94702.1 - 6.5e-17 61.5 0.3 2e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KRH94702.1 - 0.0072 16.7 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RNA_pol_Rpb1_5 PF04998.17 KRH94704.1 - 1e-68 231.7 1.7 9.9e-67 225.2 0.0 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KRH94704.1 - 4.4e-61 205.9 0.2 1.7e-60 204.1 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KRH94704.1 - 3.1e-25 88.9 0.0 3.1e-25 88.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KRH94704.1 - 2.3e-21 76.4 11.9 1.4e-18 67.3 10.4 2.7 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KRH94704.1 - 5.2e-15 55.3 0.1 5.2e-15 55.3 0.1 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 DUF4344 PF14247.6 KRH94704.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative metallopeptidase Pkinase PF00069.25 KRH94705.1 - 4.3e-23 82.0 0.8 2.2e-12 46.9 0.1 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH94705.1 - 5.1e-10 39.1 6.4 1e-07 31.6 3.1 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase SHOCT PF09851.9 KRH94707.1 - 1.5 8.6 3.8 0.79 9.5 0.5 2.3 2 0 0 2 2 2 0 Short C-terminal domain YL1_C PF08265.11 KRH94708.1 - 0.00043 20.0 0.2 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PHD PF00628.29 KRH94710.1 - 1.1e-06 28.4 9.1 2.7e-06 27.2 9.1 1.7 1 0 0 1 1 1 1 PHD-finger DZR PF12773.7 KRH94710.1 - 1.2 9.2 4.5 3.1 7.9 4.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 KRH94710.1 - 5 7.7 8.9 0.49 10.9 0.7 3.8 3 0 0 3 3 3 0 Cytochrome c3 Prok-RING_1 PF14446.6 KRH94710.1 - 8.9 6.3 8.6 0.89 9.5 3.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ODV-E18 PF10717.9 KRH94711.1 - 1.3 9.0 4.4 2.6 8.0 4.4 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PsbH PF00737.20 KRH94711.1 - 1.5 8.6 5.1 3.1 7.6 5.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Synaptobrevin PF00957.21 KRH94712.1 - 0.043 13.6 1.1 0.1 12.4 0.2 2.0 2 0 0 2 2 2 0 Synaptobrevin CDRT4 PF15213.6 KRH94713.1 - 0.015 15.9 0.3 0.022 15.3 0.3 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein RVT_1 PF00078.27 KRH94716.1 - 0.0024 17.4 0.0 0.0026 17.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) H_lectin PF09458.10 KRH94716.1 - 0.091 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 H-type lectin domain RT_RNaseH PF17917.1 KRH94717.1 - 1e-13 51.5 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94717.1 - 1.9e-09 37.5 0.0 5e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase NAC PF01849.18 KRH94717.1 - 0.018 15.0 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 NAC domain RNase_H PF00075.24 KRH94717.1 - 0.056 13.6 0.0 0.057 13.6 0.0 1.1 1 0 0 1 1 1 0 RNase H CdvA PF18822.1 KRH94720.1 - 0.48 10.3 4.7 8 6.3 0.6 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain RVP_2 PF08284.11 KRH94721.1 - 1.1e-09 38.2 0.2 1.6e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KRH94721.1 - 6.9e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94721.1 - 4.8e-06 27.1 0.0 7.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH94721.1 - 3.7e-05 24.0 0.0 6.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH94721.1 - 0.004 16.9 0.0 0.006 16.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KRH94721.1 - 0.0059 16.4 0.9 0.067 13.0 0.2 2.1 1 1 1 2 2 2 1 Putative peptidase (DUF1758) RT_RNaseH PF17917.1 KRH94722.1 - 1.5e-24 86.3 0.1 3.4e-24 85.1 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94722.1 - 1.4e-22 79.6 0.0 3.2e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 KRH94722.1 - 3.9e-18 65.8 3.1 2e-17 63.5 0.2 2.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 KRH94722.1 - 1.8e-13 50.7 0.0 9.5e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 KRH94722.1 - 9.4e-07 28.8 0.7 2.6e-06 27.4 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Glutaredoxin PF00462.24 KRH94722.1 - 0.17 12.1 0.3 6.1 7.1 0.0 3.1 3 0 0 3 3 3 0 Glutaredoxin Hexapep PF00132.24 KRH94723.1 - 6.1e-08 32.1 5.0 0.0046 16.6 0.8 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) ACI44 PF15270.6 KRH94723.1 - 3.5 7.9 22.8 1.9 8.8 2.1 4.0 2 2 2 4 4 4 0 Metallo-carboxypeptidase inhibitor GTP_EFTU PF00009.27 KRH94727.1 - 5.9e-36 123.8 0.1 7.3e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KRH94727.1 - 5.8e-12 45.9 0.1 1.5e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KRH94727.1 - 6.8e-06 26.1 0.0 3.9e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Cpn60_TCP1 PF00118.24 KRH94728.1 - 3.6e-66 223.8 1.6 2.9e-65 220.8 1.6 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AF-4 PF05110.13 KRH94729.1 - 0.0029 15.8 7.5 0.0038 15.4 7.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein IMUP PF15761.5 KRH94729.1 - 0.032 14.9 7.7 0.058 14.1 7.7 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 KRH94729.1 - 1.3 8.5 14.2 2.1 7.9 14.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1912 PF08930.10 KRH94732.1 - 0.045 13.9 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Nup54 PF13874.6 KRH94734.1 - 0.061 13.4 3.8 3.9 7.6 1.8 2.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DivIC PF04977.15 KRH94734.1 - 1.3 8.9 9.1 1.9 8.3 3.2 2.7 1 1 1 2 2 2 0 Septum formation initiator eIF-1a PF01176.19 KRH94736.1 - 9.1e-16 57.4 0.2 1.2e-15 57.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 KRH94736.1 - 0.027 14.2 0.2 0.039 13.7 0.2 1.3 1 0 0 1 1 1 0 RsgA N-terminal domain Zn_dep_PLPC PF00882.18 KRH94737.1 - 0.016 15.2 1.2 0.047 13.7 0.2 2.2 1 1 1 2 2 2 0 Zinc dependent phospholipase C TPR_8 PF13181.6 KRH94737.1 - 1.1 9.6 16.8 7 7.1 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KRH94737.1 - 1.2 9.4 14.0 6 7.2 0.6 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BING4CT PF08149.11 KRH94738.1 - 1.2e-25 89.0 0.0 3.8e-25 87.5 0.0 1.9 1 0 0 1 1 1 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 KRH94738.1 - 3e-06 26.6 1.7 0.0028 16.8 0.6 2.2 1 1 1 2 2 2 2 Coatomer WD associated region RAB3GAP2_N PF14655.6 KRH94738.1 - 0.022 14.0 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1666 PF07891.12 KRH94739.1 - 0.0015 18.2 8.3 0.0017 18.1 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1666) Phasin PF05597.11 KRH94739.1 - 0.084 12.9 1.9 0.11 12.5 1.9 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PhoU PF01895.19 KRH94739.1 - 0.13 12.7 4.8 0.9 10.0 2.6 2.1 1 1 1 2 2 2 0 PhoU domain DUF1640 PF07798.11 KRH94739.1 - 0.15 12.1 11.6 0.21 11.6 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FAM76 PF16046.5 KRH94739.1 - 0.54 9.6 7.9 0.6 9.4 7.9 1.0 1 0 0 1 1 1 0 FAM76 protein DUF2120 PF09893.9 KRH94739.1 - 0.56 10.3 6.0 2.5 8.2 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4535 PF15054.6 KRH94739.1 - 0.61 9.9 2.7 12 5.7 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4535) MRP-L51 PF10244.9 KRH94739.1 - 1.4 9.2 6.4 1.4 9.1 4.1 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit Latarcin PF10279.9 KRH94739.1 - 4.1 7.9 10.0 5.3 7.5 9.4 1.4 1 1 0 1 1 1 0 Latarcin precursor SseC PF04888.12 KRH94739.1 - 4.5 6.8 7.1 3.5 7.1 4.5 1.8 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Pescadillo_N PF06732.11 KRH94740.1 - 2.1e-14 53.8 13.9 3.1e-14 53.2 13.9 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus SMC_N PF02463.19 KRH94741.1 - 4.3e-24 85.2 46.6 2.9e-19 69.4 45.6 4.7 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KRH94741.1 - 3.7e-18 65.9 0.0 1.7e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KRH94741.1 - 1.1e-16 62.0 18.7 1.1e-16 62.0 18.7 6.9 1 1 4 5 5 5 1 AAA domain AAA_15 PF13175.6 KRH94741.1 - 3.8e-11 43.3 44.9 3.8e-11 43.3 44.9 4.6 1 1 2 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KRH94741.1 - 4.8e-10 39.7 9.2 1.3e-07 31.7 0.2 4.8 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KRH94741.1 - 3.4e-07 29.9 0.0 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KRH94741.1 - 0.019 15.0 0.0 11 6.0 0.0 3.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PAXNEB PF05625.11 KRH94742.1 - 1.3e-07 31.1 1.7 0.007 15.5 1.4 2.5 2 1 0 2 2 2 2 PAXNEB protein Chitin_synth_2 PF03142.15 KRH94744.1 - 1.6e-200 667.3 6.5 2.3e-200 666.7 6.5 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KRH94744.1 - 2.4e-12 47.3 0.0 1.2e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KRH94744.1 - 2.3e-11 44.0 7.7 2.3e-11 44.0 7.7 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KRH94744.1 - 0.00057 19.7 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 BNIP2 PF12496.8 KRH94745.1 - 3.4 8.1 13.2 0.1 13.0 2.0 2.8 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CPL PF08144.11 KRH94746.1 - 0.055 13.8 3.3 8.1 6.8 0.0 4.6 2 1 4 6 6 6 0 CPL (NUC119) domain Asparaginase PF00710.20 KRH94747.1 - 2.7e-27 95.6 0.0 1.3e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KRH94747.1 - 1.4e-08 34.9 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain PEP_hydrolase PF09370.10 KRH94747.1 - 0.0059 15.9 0.0 0.047 12.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate hydrolase-like UPF0203 PF05254.12 KRH94747.1 - 0.027 14.7 0.2 0.073 13.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Choline_transpo PF04515.12 KRH94749.1 - 1.7e-27 96.5 42.7 1.7e-27 96.5 42.7 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter FGFR3_TM PF18123.1 KRH94749.1 - 0.011 15.3 1.8 0.011 15.3 1.8 2.9 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain DUF973 PF06157.11 KRH94750.1 - 0.024 13.7 0.5 0.026 13.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF4446 PF14584.6 KRH94750.1 - 0.13 12.3 0.3 0.13 12.2 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LRR19-TM PF15176.6 KRH94750.1 - 0.14 12.2 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TMEM208_SND2 PF05620.11 KRH94752.1 - 0.017 14.9 0.7 0.018 14.8 0.7 1.0 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Ni_hydr_CYTB PF01292.20 KRH94752.1 - 0.035 13.7 0.2 0.035 13.7 0.2 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SusD-like_3 PF14322.6 KRH94754.1 - 0.089 13.1 0.1 0.089 13.1 0.1 1.0 1 0 0 1 1 1 0 Starch-binding associating with outer membrane RVT_1 PF00078.27 KRH94755.1 - 8.8e-11 41.7 1.8 1.1e-10 41.4 0.3 1.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH94755.1 - 0.029 14.2 0.8 0.05 13.4 0.2 1.7 2 0 0 2 2 2 0 Reverse transcriptase thumb domain rve PF00665.26 KRH94757.1 - 2.4e-11 43.9 0.0 2.9e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain A2M PF00207.22 KRH94757.1 - 0.06 13.2 0.2 0.13 12.1 0.1 1.6 1 1 1 2 2 2 0 Alpha-2-macroglobulin family Vps39_1 PF10366.9 KRH94760.1 - 0.047 14.0 5.3 4.1 7.7 0.1 2.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 gag-asp_proteas PF13975.6 KRH94761.1 - 2.9e-11 43.8 0.1 4e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94761.1 - 4.8e-09 36.7 0.1 7e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KRH94761.1 - 3.8e-08 33.2 2.1 7e-08 32.3 2.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KRH94761.1 - 9.7e-06 25.8 0.2 1.8e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH94761.1 - 2.8e-05 23.9 0.4 4.4e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KRH94761.1 - 4.2e-05 23.4 1.5 7.6e-05 22.5 1.5 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A2B PF12384.8 KRH94761.1 - 0.0016 18.0 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase TBD PF12845.7 KRH94761.1 - 0.14 12.1 0.4 2.9 7.8 0.0 2.9 3 0 0 3 3 3 0 TBD domain VasI PF11319.8 KRH94762.1 - 0.06 13.0 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 GCS PF03074.16 KRH94764.1 - 0.00014 21.4 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS PF03074.16 KRH94765.1 - 1.9e-17 63.7 1.5 2.2e-17 63.5 1.5 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase 4HB_MCP_1 PF12729.7 KRH94767.1 - 0.00076 19.1 0.3 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Four helix bundle sensory module for signal transduction DUF4064 PF13273.6 KRH94767.1 - 0.017 15.4 0.1 0.054 13.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Zip PF02535.22 KRH94767.1 - 0.033 13.4 0.4 0.044 13.0 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DICT PF10069.9 KRH94767.1 - 0.05 13.4 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system TarH PF02203.15 KRH94767.1 - 0.063 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF4330 PF14221.6 KRH94767.1 - 0.11 12.7 0.8 1.6 8.9 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4330) Presenilin PF01080.17 KRH94767.1 - 0.21 10.3 5.2 0.3 9.8 5.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 KRH94767.1 - 0.92 10.5 7.1 7.9 7.5 7.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) OAD_gamma PF04277.13 KRH94767.1 - 1.4 9.5 4.5 11 6.6 4.5 2.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SET_assoc PF11767.8 KRH94770.1 - 0.071 12.8 0.2 0.097 12.3 0.2 1.4 1 1 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF5113 PF17140.4 KRH94771.1 - 1.9 8.3 9.1 1 9.2 1.9 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5113) Peptidase_M1 PF01433.20 KRH94778.1 - 3.6e-40 137.8 2.4 4.6e-39 134.2 2.4 2.4 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KRH94778.1 - 5.5e-34 118.0 2.6 4.1e-33 115.1 2.6 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KRH94778.1 - 7.4e-15 55.3 0.0 1.9e-13 50.7 0.0 2.4 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Epsilon_antitox PF08998.11 KRH94778.1 - 0.1 12.9 1.3 0.29 11.4 0.3 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin tRNA-synt_2c PF01411.19 KRH94780.1 - 2.2e-138 462.2 0.2 2.6e-138 461.9 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) THUMP PF02926.17 KRH94781.1 - 6.5e-09 36.0 0.8 9.7e-09 35.5 0.1 1.5 2 0 0 2 2 2 1 THUMP domain DUF4030 PF13222.6 KRH94781.1 - 0.0059 16.8 1.6 0.015 15.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4030) SPRY PF00622.28 KRH94782.1 - 4.7e-15 55.8 0.8 7.4e-15 55.1 0.8 1.3 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 KRH94782.1 - 0.0034 17.4 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Neuralized SOTI PF17079.5 KRH94783.1 - 1.3 9.4 5.4 0.33 11.4 0.8 2.3 3 0 0 3 3 3 0 Male-specific protein scotti NDK PF00334.19 KRH94784.1 - 5.3e-47 159.2 0.0 6e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1803 PF08820.10 KRH94784.1 - 0.062 13.3 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Nab2 PF11517.8 KRH94784.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Homeodomain PF00046.29 KRH94784.1 - 0.18 11.7 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain DUF1324 PF07038.11 KRH94785.1 - 0.34 11.2 3.2 0.29 11.4 0.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1324) DHHC PF01529.20 KRH94786.1 - 4.2e-13 49.5 20.1 4.2e-13 49.5 20.1 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KRH94786.1 - 4.1e-06 27.3 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KRH94786.1 - 3.6e-05 23.8 0.2 0.00074 19.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KRH94786.1 - 4.9e-05 23.8 0.0 0.00017 22.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KRH94786.1 - 9e-05 22.7 0.1 0.012 15.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KRH94786.1 - 0.00016 21.9 0.1 0.076 13.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Presenilin PF01080.17 KRH94786.1 - 0.12 11.2 9.8 0.26 10.0 9.8 1.6 1 0 0 1 1 1 0 Presenilin DUF4359 PF14271.6 KRH94787.1 - 0.33 11.7 4.6 2.4 9.0 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) gag-asp_proteas PF13975.6 KRH94788.1 - 1.5e-08 35.1 0.0 2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KRH94788.1 - 3.2e-07 30.9 0.0 4.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KRH94788.1 - 2.1e-06 28.0 0.0 2.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KRH94788.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KRH94788.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 KRH94789.1 - 6.9e-07 29.0 0.1 9.2e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3794 PF12673.7 KRH94789.1 - 0.02 15.1 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) RT_RNaseH PF17917.1 KRH94790.1 - 5.9e-29 100.4 0.1 1.1e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94790.1 - 1.3e-24 86.1 0.0 1.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KRH94791.1 - 2.4e-10 40.4 0.3 4.2e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KRH94791.1 - 2.9e-10 40.4 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF3006 PF11213.8 KRH94792.1 - 0.0032 17.6 0.1 0.008 16.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) rve_3 PF13683.6 KRH94792.1 - 0.24 11.2 1.0 0.39 10.5 0.3 1.7 2 0 0 2 2 2 0 Integrase core domain Securin PF04856.13 KRH94795.1 - 0.011 15.7 1.5 0.014 15.3 1.5 1.1 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor LRRC37AB_C PF14914.6 KRH94795.1 - 0.027 14.4 0.9 0.027 14.4 0.9 1.7 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Syndecan PF01034.20 KRH94795.1 - 0.3 11.0 1.9 0.56 10.2 1.9 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 KRH94795.1 - 1.1 9.2 8.7 0.12 12.2 2.3 2.2 1 1 0 2 2 2 0 TMEM154 protein family Glycophorin_A PF01102.18 KRH94795.1 - 2.4 8.5 5.0 2.8 8.2 3.9 1.8 1 1 0 1 1 1 0 Glycophorin A Peptidase_C48 PF02902.19 KRH94798.1 - 1.8e-17 63.9 4.7 3.4e-17 63.0 4.6 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Shisa PF13908.6 KRH94800.1 - 0.015 15.5 0.8 0.018 15.3 0.8 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Queuosine_synth PF02547.15 KRH94802.1 - 0.049 12.7 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein MCM PF00493.23 KRH94803.1 - 1.9e-81 272.4 0.0 3.5e-81 271.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH94803.1 - 8.3e-22 77.4 1.8 8.8e-22 77.3 0.4 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KRH94803.1 - 4e-18 65.6 1.1 4e-18 65.6 1.1 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KRH94803.1 - 3.2e-06 26.7 0.0 0.0001 21.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRH94803.1 - 0.00013 22.0 0.2 0.00074 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 KRH94803.1 - 0.00022 21.7 0.3 0.00022 21.7 0.3 3.5 3 0 0 3 3 3 1 MCM N-terminal domain MMR_HSR1 PF01926.23 KRH94804.1 - 1.7e-21 76.5 1.1 3.5e-21 75.4 0.5 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KRH94804.1 - 2.2e-21 75.9 6.8 4.7e-19 68.4 4.6 2.8 2 1 0 2 2 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KRH94804.1 - 9.1e-17 60.9 0.0 2.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KRH94804.1 - 5.6e-12 45.5 0.6 2.7e-11 43.2 0.6 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KRH94804.1 - 6.5e-06 25.8 1.4 0.00063 19.3 0.9 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KRH94804.1 - 0.00027 21.2 0.2 0.016 15.4 0.0 2.6 1 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KRH94804.1 - 0.0011 18.4 0.6 0.0034 16.8 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KRH94804.1 - 0.0014 18.5 1.6 0.29 11.0 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase Arf PF00025.21 KRH94804.1 - 0.0063 16.0 0.1 0.29 10.6 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KRH94804.1 - 0.0092 15.8 0.2 0.16 11.7 0.0 2.7 2 2 1 3 3 3 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KRH94804.1 - 0.012 15.9 1.4 0.76 10.1 0.1 2.8 2 1 1 3 3 2 0 AAA domain Ras PF00071.22 KRH94804.1 - 0.024 14.3 0.2 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.23 KRH94804.1 - 0.033 14.2 5.1 2 8.4 0.1 3.5 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.27 KRH94804.1 - 0.069 13.7 1.2 0.22 12.1 1.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KRH94804.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KRH94804.1 - 0.64 9.6 5.5 20 4.8 0.1 3.1 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain BRE1 PF08647.11 KRH94804.1 - 7.3 6.7 8.4 4.6 7.4 1.8 3.1 3 1 0 3 3 2 0 BRE1 E3 ubiquitin ligase Sugar_tr PF00083.24 KRH94805.1 - 1.3e-25 90.2 38.8 4.7e-17 62.0 18.6 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KRH94805.1 - 8.6e-06 24.9 32.4 8.6e-06 24.9 32.4 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily YesK PF14150.6 KRH94806.1 - 0.23 11.7 4.1 7 6.9 0.0 2.9 2 1 1 3 3 3 0 YesK-like protein CBF PF03914.17 KRH94807.1 - 0.011 15.8 0.3 0.013 15.5 0.3 1.2 1 0 0 1 1 1 0 CBF/Mak21 family ThiF PF00899.21 KRH94808.1 - 3.5e-56 190.3 0.0 4.7e-22 78.5 0.0 4.6 4 1 0 4 4 4 4 ThiF family UBA_e1_thiolCys PF10585.9 KRH94808.1 - 1.7e-34 119.9 10.4 1.5e-20 74.2 0.0 3.5 3 1 1 4 4 4 2 Ubiquitin-activating enzyme active site HypA PF01155.19 KRH94810.1 - 0.046 13.7 0.9 0.16 12.0 0.9 1.9 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pentapeptide_4 PF13599.6 KRH94810.1 - 0.054 13.7 4.4 0.027 14.7 0.9 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) AHSA1 PF08327.11 KRH94810.1 - 0.6 10.3 5.2 0.81 9.9 0.2 2.9 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein ER PF01133.17 KRH94811.1 - 0.036 14.1 0.1 0.038 14.0 0.1 1.1 1 0 0 1 1 1 0 Enhancer of rudimentary DUF1924 PF09086.11 KRH94812.1 - 0.062 13.7 0.3 0.13 12.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) HTH_23 PF13384.6 KRH94814.1 - 0.016 15.0 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 KRH94814.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_28 PF13518.6 KRH94814.1 - 0.016 15.3 0.0 0.63 10.2 0.0 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain SANTA PF09133.10 KRH94815.1 - 0.11 13.0 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 SANTA (SANT Associated) DUF4366 PF14283.6 KRH94815.1 - 0.13 12.3 1.9 0.18 11.9 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF601 PF04642.12 KRH94818.1 - 0.017 14.6 0.9 0.031 13.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Prefoldin_2 PF01920.20 KRH94819.1 - 0.011 15.7 1.0 0.038 13.9 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit ApoO PF09769.9 KRH94820.1 - 0.00022 21.2 4.1 0.023 14.6 0.4 3.2 1 1 2 3 3 3 1 Apolipoprotein O Perilipin PF03036.16 KRH94820.1 - 0.0019 17.3 3.4 0.059 12.4 0.3 2.6 1 1 2 3 3 3 1 Perilipin family DUF3584 PF12128.8 KRH94820.1 - 0.0026 15.4 2.8 0.0032 15.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF883 PF05957.13 KRH94820.1 - 0.0033 18.0 1.2 0.017 15.7 0.5 2.4 2 1 1 3 3 2 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 KRH94820.1 - 0.017 15.2 20.5 0.029 14.5 14.9 3.0 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF885 PF05960.11 KRH94820.1 - 0.017 14.8 1.8 0.024 14.3 1.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Phasin PF05597.11 KRH94820.1 - 0.04 13.9 2.2 1.5 8.9 1.4 3.0 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2959 PF11172.8 KRH94820.1 - 0.041 14.0 11.4 4.2 7.4 0.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) Apolipoprotein PF01442.18 KRH94820.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HisKA_3 PF07730.13 KRH94820.1 - 0.077 13.5 0.0 12 6.5 0.1 3.0 2 1 0 2 2 2 0 Histidine kinase DUF4854 PF16146.5 KRH94820.1 - 0.085 13.2 6.6 5 7.5 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4854) AIP3 PF03915.13 KRH94820.1 - 0.12 11.4 4.0 0.24 10.4 4.0 1.5 1 0 0 1 1 1 0 Actin interacting protein 3 DUF842 PF05811.13 KRH94820.1 - 0.14 11.9 0.4 0.35 10.6 0.4 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Prominin PF05478.11 KRH94820.1 - 0.16 9.9 16.9 0.3 9.0 10.4 2.2 1 1 1 2 2 2 0 Prominin DUF1640 PF07798.11 KRH94820.1 - 0.27 11.3 13.5 2.8 7.9 13.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) LXG PF04740.12 KRH94820.1 - 0.29 10.8 18.8 0.28 10.9 5.2 3.1 1 1 2 3 3 3 0 LXG domain of WXG superfamily Mitofilin PF09731.9 KRH94820.1 - 0.41 9.4 8.2 0.57 9.0 8.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med9 PF07544.13 KRH94820.1 - 0.49 10.5 3.1 9.7 6.4 1.3 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Tape_meas_lam_C PF09718.10 KRH94820.1 - 0.81 9.9 16.1 20 5.4 5.9 3.8 1 1 3 4 4 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Uso1_p115_C PF04871.13 KRH94820.1 - 0.92 9.9 4.3 1.3 9.4 2.5 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Chlorosome_CsmC PF11098.8 KRH94820.1 - 1 9.4 14.8 0.45 10.5 9.0 2.7 1 1 1 2 2 2 0 Chlorosome envelope protein C PIN_8 PF18476.1 KRH94820.1 - 1 9.2 14.7 0.27 11.1 8.0 2.2 1 1 1 2 2 2 0 PIN like domain Focal_AT PF03623.13 KRH94820.1 - 1.1 9.2 6.3 0.79 9.7 4.0 1.8 2 0 0 2 2 2 0 Focal adhesion targeting region TBCC_N PF16752.5 KRH94820.1 - 1.5 9.2 8.4 30 5.1 6.2 3.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain SMBP PF16785.5 KRH94820.1 - 1.7 8.9 14.7 24 5.2 10.4 3.2 1 1 1 2 2 2 0 Small metal-binding protein YtxH PF12732.7 KRH94820.1 - 1.7 9.2 9.3 4.1e+02 1.6 9.3 4.0 1 1 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.18 KRH94820.1 - 1.7 8.7 15.9 0.21 11.7 11.2 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) ZYG-11_interact PF05884.12 KRH94820.1 - 1.9 7.8 5.3 2.5 7.4 4.4 1.6 1 1 1 2 2 2 0 Interactor of ZYG-11 SPECT1 PF18680.1 KRH94820.1 - 2.3 7.9 16.9 3.8 7.1 16.9 1.4 1 1 0 1 1 1 0 Plasmodium host cell traversal SPECT1 DUF2130 PF09903.9 KRH94820.1 - 2.4 7.3 16.6 13 4.9 13.3 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) DivIVA PF05103.13 KRH94820.1 - 3.4 7.8 18.0 1 9.5 13.3 2.3 1 1 1 2 2 2 0 DivIVA protein Vps23_core PF09454.10 KRH94820.1 - 3.5 7.6 7.2 8.4 6.4 0.3 4.1 2 2 2 4 4 4 0 Vps23 core domain Syntaxin PF00804.25 KRH94820.1 - 5.5 6.6 7.0 11 5.6 4.7 2.1 2 0 0 2 2 2 0 Syntaxin PTS_IIA PF02255.16 KRH94820.1 - 5.9 7.0 9.6 20 5.3 7.3 2.7 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit RasGAP_C PF03836.15 KRH94820.1 - 5.9 7.0 10.9 10 6.3 8.4 2.5 2 1 0 2 2 2 0 RasGAP C-terminus FAM25 PF15825.5 KRH94820.1 - 6 7.3 18.3 1.3 9.4 4.0 4.3 2 2 1 4 4 4 0 FAM25 family Z1 PF10593.9 KRH94820.1 - 6.1 6.3 15.9 1.3 8.5 2.2 2.2 1 1 1 2 2 2 0 Z1 domain Phage_connect_1 PF05135.13 KRH94820.1 - 8.8 6.9 15.3 3.7e+03 -1.5 15.0 3.8 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Ribosomal_S26e PF01283.19 KRH94823.1 - 4.9e-41 139.5 7.9 5.3e-41 139.4 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Sec1 PF00995.23 KRH94824.1 - 1.5e-26 93.8 33.9 6.2e-26 91.8 31.5 2.5 1 1 1 2 2 2 2 Sec1 family QueF_N PF14819.6 KRH94824.1 - 1.8 8.9 5.8 0.27 11.6 1.2 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term ABC_tran PF00005.27 KRH94825.1 - 9.7e-21 74.7 4.0 1.8e-19 70.6 0.6 2.9 2 1 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 KRH94825.1 - 3.8e-18 65.7 21.5 3.8e-18 65.7 21.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 KRH94825.1 - 3.1e-07 30.5 3.6 3.1e-07 30.5 3.6 2.5 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KRH94825.1 - 0.0017 18.3 0.0 0.0047 16.8 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KRH94825.1 - 0.012 15.8 0.0 0.048 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRH94825.1 - 0.02 14.6 0.2 0.02 14.6 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KRH94825.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KRH94825.1 - 0.068 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KRH94825.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KRH94825.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KRH94825.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KRH94825.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain CDC50 PF03381.15 KRH94827.1 - 0.00038 20.1 0.0 0.00038 20.1 0.0 1.5 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNA_pol_Rpb8 PF03870.15 KRH94828.1 - 3.5e-06 27.3 0.2 2.1e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 DUF5461 PF17545.2 KRH94828.1 - 0.045 14.1 0.0 0.099 13.0 0.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5461) DUF3987 PF13148.6 KRH94829.1 - 0.55 9.2 2.5 0.85 8.6 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_tran PF00005.27 KRH94830.1 - 1.7e-28 99.8 16.5 2.5e-16 60.5 0.0 4.5 4 2 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 KRH94830.1 - 3.1e-19 69.9 20.1 1.4e-07 31.6 0.2 5.3 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KRH94830.1 - 4.3e-09 36.3 9.2 4.3e-09 36.3 9.2 2.4 3 0 0 3 3 1 1 ABC transporter SMC_N PF02463.19 KRH94830.1 - 5.1e-08 32.6 25.6 0.0057 16.1 11.9 4.5 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KRH94830.1 - 3.3e-05 23.5 0.8 0.011 15.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KRH94830.1 - 0.00032 21.1 0.0 0.047 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KRH94830.1 - 0.0017 18.8 0.0 6.4 7.2 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KRH94830.1 - 0.0024 17.8 0.2 0.0024 17.8 0.2 3.6 4 0 0 4 4 4 1 RsgA GTPase AAA_24 PF13479.6 KRH94830.1 - 0.0034 17.1 7.9 0.046 13.4 0.0 3.3 4 0 0 4 4 4 2 AAA domain DUF815 PF05673.13 KRH94830.1 - 0.0038 16.4 0.2 0.11 11.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 KRH94830.1 - 0.0048 16.8 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 KRH94830.1 - 0.0056 17.2 1.6 0.0056 17.2 1.6 4.9 3 2 1 4 4 3 1 AAA domain SbcCD_C PF13558.6 KRH94830.1 - 0.0091 16.2 0.4 6.1 7.2 0.1 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KRH94830.1 - 0.013 15.7 2.0 0.35 11.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 KRH94830.1 - 0.027 14.2 0.5 0.5 10.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 KRH94830.1 - 0.03 14.3 3.1 4.7 7.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KRH94830.1 - 0.053 13.7 0.5 5.9 7.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KRH94830.1 - 0.13 12.7 11.4 0.89 10.0 0.0 4.0 4 0 0 4 4 3 0 RNA helicase Roc PF08477.13 KRH94830.1 - 0.32 11.2 3.9 3.6 7.8 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KRH94830.1 - 0.4 10.8 5.9 6.1 7.0 0.0 3.3 3 1 0 3 3 3 0 50S ribosome-binding GTPase ubiquitin PF00240.23 KRH94831.1 - 5.9e-15 54.8 0.3 7.3e-15 54.5 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KRH94831.1 - 1.9e-05 24.4 0.1 2.2e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KRH94831.1 - 7.6e-05 22.6 0.0 8.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KRH94831.1 - 0.0066 17.0 0.0 0.0075 16.8 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KRH94831.1 - 0.011 16.0 0.0 0.012 15.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain DNApol_Exo PF18136.1 KRH94832.1 - 0.16 11.0 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain Get5_bdg PF16843.5 KRH94833.1 - 0.038 13.5 0.7 1.4 8.5 0.1 3.4 3 0 0 3 3 3 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DUF4208 PF13907.6 KRH94833.1 - 3.1 8.3 9.1 0.2 12.1 1.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) CLU_N PF15044.6 KRH94833.1 - 3.8 8.0 6.6 13 6.3 0.3 4.4 4 0 0 4 4 4 0 Mitochondrial function, CLU-N-term KH_1 PF00013.29 KRH94835.1 - 6.2e-12 45.2 15.8 1.5e-07 31.1 0.0 5.2 4 1 0 4 4 4 2 KH domain Pentapeptide PF00805.22 KRH94835.1 - 0.0016 18.0 0.1 0.005 16.5 0.1 1.9 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 KRH94835.1 - 0.01 16.0 2.5 0.11 12.6 0.1 3.3 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Homeodomain PF00046.29 KRH94838.1 - 8.1e-10 38.4 0.7 1.1e-09 38.0 0.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH94838.1 - 0.00017 21.4 0.2 0.00027 20.8 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain Crystall_3 PF08964.10 KRH94838.1 - 0.03 14.5 0.1 0.038 14.2 0.1 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin RVT_1 PF00078.27 KRH94842.1 - 6.4e-10 38.9 0.2 9.1e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 KRH94843.1 - 7.3e-06 25.7 0.2 1.5e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain PUF PF00806.19 KRH94845.1 - 9.4e-42 138.4 19.5 5e-06 25.9 0.0 8.6 7 1 1 8 8 8 8 Pumilio-family RNA binding repeat S1 PF00575.23 KRH94846.1 - 6.2e-06 26.5 0.1 1.5e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KRH94846.1 - 0.00064 20.0 0.1 0.0013 19.1 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF4861 PF16153.5 KRH94846.1 - 0.18 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) Kinesin PF00225.23 KRH94847.1 - 5.6e-25 88.0 28.6 2e-21 76.3 0.9 4.8 3 2 1 4 4 4 3 Kinesin motor domain HHH_3 PF12836.7 KRH94847.1 - 0.00015 21.9 0.7 0.00053 20.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_22 PF13401.6 KRH94847.1 - 0.0097 16.2 1.5 0.026 14.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain HHH PF00633.23 KRH94847.1 - 0.043 13.7 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PTH2 PF01981.16 KRH94850.1 - 9.8e-26 90.3 0.1 1.6e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SNAD3 PF18749.1 KRH94850.1 - 0.0037 16.5 0.5 0.0047 16.2 0.5 1.1 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 F-box_4 PF15966.5 KRH94850.1 - 0.042 13.7 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 F-box Baculo_LEF-11 PF06385.12 KRH94850.1 - 0.28 11.7 3.4 12 6.4 1.1 2.5 2 1 0 2 2 2 0 Baculovirus LEF-11 protein STE PF02200.16 KRH94851.1 - 1.4e-53 179.9 0.5 2.7e-53 179.0 0.5 1.5 1 0 0 1 1 1 1 STE like transcription factor Rv2175c_C PF18367.1 KRH94851.1 - 2.9e-05 24.1 0.1 4.3 7.5 0.0 4.9 1 1 3 4 4 4 2 Rv2175c C-terminal domain of unknown function Choline_kinase PF01633.20 KRH94854.1 - 1.2e-42 145.9 6.2 2.5e-42 144.9 6.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KRH94854.1 - 6.4e-05 23.0 0.0 0.22 11.4 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 KRH94854.1 - 0.27 10.5 9.6 0.017 14.4 2.0 2.5 3 0 0 3 3 3 0 Ecdysteroid kinase RVT_1 PF00078.27 KRH94855.1 - 7e-27 94.4 0.5 1.5e-26 93.3 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 KRH94855.1 - 1.7e-26 92.5 0.1 6.5e-26 90.7 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KRH94855.1 - 2.5e-24 85.2 0.0 6.6e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNase_H PF00075.24 KRH94855.1 - 0.0072 16.5 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 RNase H RVT_thumb PF06817.14 KRH94855.1 - 0.0094 15.8 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Fib_alpha PF08702.10 KRH94855.1 - 5 7.3 5.5 24 5.1 0.0 3.7 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Peptidase_C48 PF02902.19 KRH94857.1 - 2.3e-14 53.8 5.7 2.9e-14 53.4 5.7 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TcdB_N PF12918.7 KRH94858.1 - 0.028 14.7 2.0 0.067 13.5 0.2 2.6 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF2373 PF10180.9 KRH94860.1 - 0.065 13.1 0.1 0.076 12.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DisA_N PF02457.16 KRH94861.1 - 0.0077 15.8 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding PriC PF07445.12 KRH94865.1 - 0.00024 21.1 0.7 0.00031 20.7 0.7 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC DUF2608 PF11019.8 KRH94865.1 - 0.016 14.7 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF1878 PF08963.10 KRH94865.1 - 0.058 13.9 0.1 0.058 13.9 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1878) BORCS7 PF16088.5 KRH94865.1 - 0.2 11.9 2.1 3.1 8.1 0.1 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Helicase_C_2 PF13307.6 KRH94866.1 - 3.6e-37 128.2 0.5 1.2e-36 126.4 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 KRH94866.1 - 2.4e-36 125.0 1.2 4.7e-36 124.0 0.3 2.0 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KRH94866.1 - 2.8e-07 30.4 0.8 0.014 15.1 0.1 3.0 3 0 0 3 3 3 2 Helical and beta-bridge domain DEAD PF00270.29 KRH94866.1 - 1.5e-06 28.1 0.0 0.004 16.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KRH94866.1 - 1.9e-06 28.0 0.4 1.3e-05 25.3 0.3 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KRH94866.1 - 0.003 17.0 0.1 0.098 12.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein rpo30_N PF12410.8 KRH94866.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.9 3 0 0 3 3 3 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit RRM_1 PF00076.22 KRH94868.1 - 7.1e-37 125.1 2.4 6.6e-19 67.5 0.4 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KRH94868.1 - 5.9e-11 42.3 0.1 7.1e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 KRH94868.1 - 4.2e-05 23.4 0.2 0.014 15.3 0.1 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Cohesin_HEAT PF12765.7 KRH94868.1 - 0.077 13.3 2.4 0.14 12.5 2.4 1.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion V_ATPase_I PF01496.19 KRH94871.1 - 0.32 8.9 23.1 0.37 8.6 23.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2992 PF11208.8 KRH94871.1 - 0.74 10.1 31.6 1 9.6 31.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) APG6_N PF17675.1 KRH94871.1 - 1.3 9.5 22.5 1.7 9.2 22.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 KRH94871.1 - 2.8 8.2 10.7 0.99 9.7 7.1 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2335 PF10097.9 KRH94871.1 - 3.2 7.8 8.6 1 9.4 4.1 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2335) Presenilin PF01080.17 KRH94871.1 - 4.1 6.1 20.7 4.5 5.9 20.7 1.0 1 0 0 1 1 1 0 Presenilin Phage_GPO PF05929.11 KRH94871.1 - 4.2 6.9 18.0 5.1 6.6 18.0 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3450 PF11932.8 KRH94871.1 - 6.8 5.9 21.3 12 5.1 21.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Zip PF02535.22 KRH94871.1 - 8.8 5.4 17.0 11 5.1 17.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Exonuc_VII_L PF02601.15 KRH94871.1 - 9.5 5.7 21.3 10 5.6 21.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tubulin PF00091.25 KRH94872.1 - 2.2e-69 233.6 0.2 3.9e-69 232.8 0.2 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KRH94872.1 - 1.7e-42 144.5 0.1 2.9e-42 143.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KRH94872.1 - 6.8e-07 29.6 0.6 1.2e-06 28.8 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KRH94872.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain RRM_1 PF00076.22 KRH94874.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTP2 PF17022.5 KRH94875.1 - 6.4e-40 137.1 8.7 8.7e-40 136.6 8.7 1.1 1 0 0 1 1 1 1 Polar tube protein 2 from Microsporidia U5_2-snRNA_bdg PF10597.9 KRH94877.1 - 6.8e-05 23.0 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 U6-snRNA_bdg PF10596.9 KRH94877.1 - 0.0003 20.8 0.1 0.0003 20.8 0.1 3.8 5 0 0 5 5 5 1 U6-snRNA interacting domain of PrP8 KinB_sensor PF16767.5 KRH94877.1 - 0.036 14.5 0.3 0.21 12.1 0.1 2.4 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Aa_trans PF01490.18 KRH94878.1 - 2.2e-31 109.0 54.3 1.3e-25 90.0 47.0 2.3 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein SpoIIIAH PF12685.7 KRH94878.1 - 0.0036 17.2 0.1 0.0036 17.2 0.1 1.8 2 0 0 2 2 2 1 SpoIIIAH-like protein FA_desaturase PF00487.24 KRH94878.1 - 0.01 15.7 1.9 0.01 15.7 1.9 3.2 3 2 1 4 4 4 0 Fatty acid desaturase Polysacc_synt_C PF14667.6 KRH94878.1 - 0.015 15.4 6.7 0.015 15.4 6.7 4.3 5 0 0 5 5 5 0 Polysaccharide biosynthesis C-terminal domain CD34_antigen PF06365.12 KRH94878.1 - 0.13 11.8 3.3 13 5.3 0.2 3.2 3 0 0 3 3 3 0 CD34/Podocalyxin family NOA36 PF06524.12 KRH94878.1 - 3.2 7.0 5.7 5.5 6.2 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein UNC45-central PF11701.8 KRH94878.1 - 4.2 7.3 5.9 0.24 11.3 0.4 1.7 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Aa_trans PF01490.18 KRH94879.1 - 2.9e-37 128.4 42.7 3.5e-37 128.1 42.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KRH94879.1 - 1.4 7.9 32.7 11 4.9 32.7 2.1 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family APG6_N PF17675.1 KRH94881.1 - 0.0029 18.2 17.3 0.0049 17.4 17.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc24 PF08286.11 KRH94881.1 - 0.0076 16.5 2.2 0.0076 16.5 2.2 2.4 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4600 PF15372.6 KRH94881.1 - 0.081 13.4 9.6 0.17 12.3 9.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) PhoU PF01895.19 KRH94881.1 - 0.091 13.2 0.4 0.19 12.2 0.4 1.6 1 0 0 1 1 1 0 PhoU domain MBR1 PF17058.5 KRH94881.1 - 0.094 13.0 1.1 0.11 12.8 1.1 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 APG12 PF04110.13 KRH94881.1 - 0.14 12.5 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Macoilin PF09726.9 KRH94881.1 - 0.19 10.2 11.7 0.047 12.3 4.6 1.9 1 1 1 2 2 2 0 Macoilin family Golgin_A5 PF09787.9 KRH94881.1 - 0.29 10.6 14.7 0.36 10.2 14.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3450 PF11932.8 KRH94881.1 - 0.4 9.9 10.9 0.23 10.7 8.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NBP1 PF08537.10 KRH94881.1 - 0.41 10.0 9.3 0.58 9.5 9.3 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 BRE1 PF08647.11 KRH94881.1 - 0.73 9.9 14.5 0.22 11.6 6.0 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase 3-PAP PF12578.8 KRH94881.1 - 0.79 9.5 6.4 3.6 7.3 0.5 3.1 2 1 1 3 3 3 0 Myotubularin-associated protein Exonuc_VII_L PF02601.15 KRH94881.1 - 0.96 9.0 6.6 1 8.9 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MobC PF05713.11 KRH94881.1 - 1.2 9.7 5.9 9.3 6.8 0.6 3.7 4 0 0 4 4 4 0 Bacterial mobilisation protein (MobC) DUF29 PF01724.16 KRH94881.1 - 1.2 9.4 9.4 2.1 8.6 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 Fib_alpha PF08702.10 KRH94881.1 - 1.4 9.1 9.8 4.7 7.4 9.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 KRH94881.1 - 1.6 8.8 6.8 4.5 7.3 3.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KRH94881.1 - 2.1 8.4 6.4 3.8 7.5 2.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Wbp11 PF09429.10 KRH94881.1 - 2.8 8.4 12.9 8.1 6.9 1.6 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 DUF4404 PF14357.6 KRH94881.1 - 3.4 8.4 13.0 1.7 9.3 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ACCA PF03255.14 KRH94881.1 - 4.3 7.2 9.2 5.3 6.9 2.3 2.3 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PRKG1_interact PF15898.5 KRH94881.1 - 5.2 8.0 12.6 41 5.2 2.6 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DASH_Dam1 PF08653.10 KRH94881.1 - 6.3 6.7 6.0 13 5.6 1.2 3.3 3 1 0 3 3 3 0 DASH complex subunit Dam1 TMPIT PF07851.13 KRH94881.1 - 7.8 5.6 8.3 11 5.2 8.3 1.4 1 1 0 1 1 1 0 TMPIT-like protein Med9 PF07544.13 KRH94881.1 - 9 6.5 14.4 6.2 7.0 0.2 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 KRH94881.1 - 9.1 4.8 9.8 9.1 4.8 9.1 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S24 PF00717.23 KRH94882.1 - 8.9e-09 35.2 0.1 1.4e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like FSA_C PF10479.9 KRH94883.1 - 0.24 9.5 9.4 0.31 9.1 9.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fringe PF02434.16 KRH94889.1 - 0.04 13.3 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Fringe-like tRNA-synt_2b PF00587.25 KRH94890.1 - 1.2e-06 28.6 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1179 PF06678.11 KRH94891.1 - 0.7 9.9 2.4 0.54 10.3 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) DUF2180 PF09947.9 KRH94893.1 - 0.068 13.2 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) KIP1 PF07765.12 KRH94894.1 - 0.16 12.1 1.9 2.9 8.1 0.0 2.8 3 0 0 3 3 3 0 KIP1-like protein Pep_deformylase PF01327.21 KRH94894.1 - 0.35 10.5 3.1 10 5.7 0.1 3.0 3 0 0 3 3 3 0 Polypeptide deformylase rve PF00665.26 KRH94896.1 - 0.11 12.6 0.5 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 Integrase core domain WW_1 PF18507.1 KRH94899.1 - 0.019 14.6 0.2 0.037 13.7 0.2 1.4 1 0 0 1 1 1 0 WW domain DUF1106 PF06523.11 KRH94900.1 - 0.027 14.5 1.8 0.2 11.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1106) DUF5050 PF16472.5 KRH94902.1 - 2.6e-06 26.9 2.9 3.4e-06 26.5 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) WD40_like PF17005.5 KRH94902.1 - 1e-05 25.1 6.0 3.6e-05 23.2 5.9 1.8 1 1 0 1 1 1 1 WD40-like domain DUF3930 PF13067.6 KRH94902.1 - 0.03 14.6 0.3 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) PQQ_2 PF13360.6 KRH94902.1 - 0.034 13.7 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain Sec6 PF06046.13 KRH94903.1 - 7.5e-36 123.6 13.5 7.5e-36 123.6 13.5 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF1664 PF07889.12 KRH94903.1 - 0.0018 18.3 3.3 0.0075 16.3 3.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KRH94903.1 - 0.12 12.4 6.7 0.16 12.0 3.5 2.6 1 1 1 2 2 2 0 Laminin Domain II AAA_assoc_C PF09821.9 KRH94903.1 - 0.29 11.7 5.3 4.6 7.8 0.4 3.9 3 0 0 3 3 3 0 C-terminal AAA-associated domain Sec20 PF03908.13 KRH94903.1 - 1.2 9.1 6.0 1.4 8.9 1.5 3.3 2 1 1 3 3 3 0 Sec20 DUF745 PF05335.13 KRH94903.1 - 1.9 8.2 3.8 2.3 7.9 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) JAKMIP_CC3 PF16034.5 KRH94903.1 - 5.5 6.9 15.6 2.6 7.9 6.7 3.1 1 1 1 2 2 2 0 JAKMIP CC3 domain DASH_Duo1 PF08651.10 KRH94903.1 - 7 6.5 11.8 11 5.9 2.8 3.6 3 1 0 3 3 3 0 DASH complex subunit Duo1 Npa1 PF11707.8 KRH94908.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal CP12 PF02672.15 KRH94909.1 - 0.22 12.3 0.0 0.32 11.8 0.0 1.2 1 0 0 1 1 1 0 CP12 domain KGK PF08872.10 KRH94910.1 - 0.024 15.1 0.7 0.03 14.8 0.7 1.1 1 0 0 1 1 1 0 KGK domain tRNA-synt_1 PF00133.22 KRH94914.1 - 6.1e-183 609.3 0.2 1.7e-180 601.3 0.2 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KRH94914.1 - 1.1e-23 83.9 1.0 2.9e-23 82.5 0.4 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KRH94914.1 - 5.1e-17 61.7 3.9 0.00015 20.6 0.1 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) RhoGAP-FF1 PF16512.5 KRH94914.1 - 0.043 14.5 0.3 0.15 12.7 0.3 1.9 1 0 0 1 1 1 0 p190-A and -B Rho GAPs FF domain ABC_tran PF00005.27 KRH94921.1 - 8.2e-27 94.4 0.1 2.1e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KRH94921.1 - 7.8e-09 35.3 0.6 1.8e-08 34.1 0.6 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KRH94921.1 - 6.5e-07 29.5 3.3 0.00096 19.0 0.3 2.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KRH94921.1 - 0.00038 20.7 0.2 0.00097 19.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KRH94921.1 - 0.00062 20.3 2.4 0.0015 19.0 2.5 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KRH94921.1 - 0.00089 19.2 1.1 0.0015 18.5 0.1 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KRH94921.1 - 0.0068 16.1 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KRH94921.1 - 0.0072 16.1 2.0 0.15 11.8 0.5 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 KRH94921.1 - 0.0076 16.6 0.2 0.017 15.5 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KRH94921.1 - 0.0085 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KRH94921.1 - 0.011 14.9 0.3 0.021 13.9 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SbcCD_C PF13558.6 KRH94921.1 - 0.023 14.9 0.0 0.26 11.5 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KRH94921.1 - 0.026 14.6 0.4 0.072 13.2 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.18 KRH94921.1 - 0.028 14.1 0.2 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 KRH94921.1 - 0.034 14.2 0.1 0.072 13.1 0.1 1.6 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 KRH94921.1 - 0.058 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KRH94921.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KRH94921.1 - 0.11 11.9 0.1 0.32 10.3 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KRH94921.1 - 0.13 12.2 0.4 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.29 KRH94921.1 - 0.17 12.3 2.9 1.6 9.2 1.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KRH94921.1 - 0.22 11.2 0.5 0.42 10.3 0.5 1.3 1 0 0 1 1 1 0 AAA domain PV_NSP1 PF12433.8 KRH94922.1 - 0.0019 18.5 0.4 0.0019 18.5 0.4 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein 1 MFS_1 PF07690.16 KRH94923.1 - 7.6e-13 48.1 41.8 6.8e-07 28.5 7.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 KRH94923.1 - 0.0018 16.8 2.4 0.0028 16.1 2.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Fungal_trans_2 PF11951.8 KRH94923.1 - 0.012 14.5 0.3 0.29 9.9 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF3450 PF11932.8 KRH94923.1 - 0.06 12.6 0.5 0.13 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Plus-3 PF03126.18 KRH94924.1 - 6.4e-14 52.4 0.7 6.4e-14 52.4 0.7 2.4 3 1 0 3 3 3 1 Plus-3 domain SNF2_N PF00176.23 KRH94925.1 - 2.7e-49 167.8 1.9 2.7e-49 167.8 1.9 2.5 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KRH94925.1 - 1.3e-17 64.2 0.4 1.8e-16 60.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 KRH94925.1 - 3.7e-10 39.6 0.2 0.00016 21.5 0.0 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KRH94925.1 - 3.4e-08 33.7 0.0 3.4e-08 33.7 0.0 5.2 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KRH94925.1 - 9.9e-08 31.9 0.1 4.6e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase TFIIA PF03153.13 KRH94925.1 - 0.00065 19.8 23.8 0.00065 19.8 23.8 4.7 3 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit DUF5340 PF17275.2 KRH94925.1 - 0.0071 16.5 0.1 0.051 13.7 0.0 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5340) DMAP1_like PF17024.5 KRH94926.1 - 8.1e-21 74.3 12.2 9.9e-21 74.0 12.2 1.1 1 0 0 1 1 1 1 Putative DMAP1-like FadR_C PF07840.12 KRH94926.1 - 0.0068 16.3 0.3 0.016 15.1 0.2 1.5 1 1 0 1 1 1 1 FadR C-terminal domain Lipid_DES PF08557.10 KRH94926.1 - 0.085 12.4 0.3 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) CBFD_NFYB_HMF PF00808.23 KRH94928.1 - 2e-11 44.0 2.0 5.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KRH94928.1 - 2.3e-06 28.0 4.6 7.1e-06 26.4 4.6 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 GTP_EFTU PF00009.27 KRH94929.1 - 1.4e-60 204.1 0.0 2e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KRH94929.1 - 4.3e-22 77.9 0.0 1.1e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KRH94929.1 - 1.5e-21 76.4 0.0 5.4e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KRH94929.1 - 3.9e-13 49.3 0.0 9.8e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KRH94929.1 - 3.4e-11 43.4 0.7 8.2e-11 42.1 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KRH94929.1 - 0.0018 18.3 0.1 0.0049 16.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRH94929.1 - 0.059 13.3 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TP_methylase PF00590.20 KRH94931.1 - 2.6e-15 56.9 0.0 7.3e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases AAA_2 PF07724.14 KRH94932.1 - 3.1e-42 144.6 1.1 1.2e-37 129.7 0.2 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KRH94932.1 - 1.7e-26 92.2 0.2 1.7e-26 92.2 0.2 3.7 5 0 0 5 5 2 1 AAA lid domain AAA PF00004.29 KRH94932.1 - 3.4e-23 82.5 2.0 4e-13 49.9 0.1 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH94932.1 - 8.4e-18 64.7 0.7 1.9e-10 40.8 0.0 4.0 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KRH94932.1 - 4.5e-14 52.3 0.5 2.9e-13 49.7 0.5 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KRH94932.1 - 1.6e-10 41.7 0.1 0.0012 19.3 0.0 5.0 5 1 0 5 5 4 2 AAA ATPase domain AAA_7 PF12775.7 KRH94932.1 - 1.7e-09 37.4 1.1 9.5e-05 22.0 0.0 3.3 4 0 0 4 4 4 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KRH94932.1 - 4.8e-09 36.2 0.0 0.00073 19.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 KRH94932.1 - 7e-08 32.1 0.5 0.004 16.6 0.0 4.0 3 1 1 4 4 4 2 Bacterial TniB protein AAA_18 PF13238.6 KRH94932.1 - 4.8e-07 30.4 1.6 0.025 15.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 KRH94932.1 - 4.8e-07 29.6 0.5 0.00037 20.3 0.0 3.3 3 1 0 3 3 3 1 Sigma-54 interaction domain Clp_N PF02861.20 KRH94932.1 - 3.5e-06 27.0 0.0 1.3e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 Clp amino terminal domain, pathogenicity island component AAA_14 PF13173.6 KRH94932.1 - 3.6e-06 27.1 4.5 0.028 14.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 KRH94932.1 - 2.4e-05 24.3 0.0 0.031 14.2 0.0 3.0 3 0 0 3 3 2 1 NACHT domain ATPase_2 PF01637.18 KRH94932.1 - 4.5e-05 23.5 16.2 0.014 15.3 0.1 5.2 3 2 2 5 5 5 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KRH94932.1 - 9.5e-05 22.7 3.2 0.64 10.3 0.0 4.3 3 2 1 4 4 3 2 AAA domain RuvB_N PF05496.12 KRH94932.1 - 0.0001 22.1 2.5 0.16 11.7 0.0 4.1 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KRH94932.1 - 0.00022 20.7 0.3 1.2 8.5 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KRH94932.1 - 0.00039 20.4 0.0 0.81 9.7 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KRH94932.1 - 0.00045 20.6 0.7 0.86 10.0 0.0 3.3 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 KRH94932.1 - 0.00054 20.2 0.3 0.66 10.2 0.0 3.1 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KRH94932.1 - 0.0014 18.4 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KRH94932.1 - 0.0021 18.0 3.5 0.89 9.4 0.0 3.6 3 1 0 4 4 3 2 RsgA GTPase DNA_pol3_delta2 PF13177.6 KRH94932.1 - 0.0027 17.5 0.5 0.26 11.1 0.0 3.6 4 0 0 4 4 3 1 DNA polymerase III, delta subunit SRP54 PF00448.22 KRH94932.1 - 0.0036 16.9 0.2 0.98 9.0 0.0 2.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KRH94932.1 - 0.0041 16.8 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KRH94932.1 - 0.0055 15.9 0.0 3.8 6.6 0.0 3.1 2 0 0 2 2 2 1 NB-ARC domain Torsin PF06309.11 KRH94932.1 - 0.007 16.5 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Torsin AAA_19 PF13245.6 KRH94932.1 - 0.0074 16.6 0.1 1.5 9.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_6 PF12774.7 KRH94932.1 - 0.0077 15.2 8.2 3.2 6.6 0.0 4.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 KRH94932.1 - 0.012 15.1 0.0 0.97 9.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 KRH94932.1 - 0.013 15.4 0.1 0.53 10.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KRH94932.1 - 0.034 13.9 0.1 2.3 8.0 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KRH94932.1 - 0.056 13.6 0.5 9.5 6.4 0.0 3.3 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KRH94932.1 - 0.075 12.8 0.0 4 7.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RVT_N PF13655.6 KRH94932.1 - 0.17 12.1 2.9 2.9 8.2 0.2 3.0 3 0 0 3 3 2 0 N-terminal domain of reverse transcriptase ResIII PF04851.15 KRH94932.1 - 0.18 11.8 10.1 3.7 7.5 0.1 4.4 4 1 1 5 5 4 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KRH94932.1 - 0.28 11.3 10.2 0.38 10.8 0.5 4.2 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KRH94932.1 - 0.42 11.1 12.3 0.43 11.1 0.2 4.0 3 3 0 3 3 2 0 ABC transporter CagY_M PF07337.11 KRH94932.1 - 1.2 8.9 5.5 6.3 6.5 1.6 2.7 2 0 0 2 2 2 0 DC-EC Repeat BST2 PF16716.5 KRH94932.1 - 3.2 8.4 7.7 6.9 7.3 2.4 3.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 tRNA-synt_2 PF00152.20 KRH94933.1 - 8.6e-57 192.6 7.2 1.7e-56 191.6 7.2 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KRH94933.1 - 6.7e-05 22.8 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Poty_PP PF08440.10 KRH94933.1 - 0.042 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Potyviridae polyprotein RNA_pol_Rpb4 PF03874.16 KRH94934.1 - 6e-08 33.1 10.8 8.3e-08 32.6 10.8 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Sybindin PF04099.12 KRH94936.1 - 2.2e-09 37.4 1.7 4.8e-09 36.3 1.7 1.5 1 1 0 1 1 1 1 Sybindin-like family Acetyltransf_19 PF18015.1 KRH94936.1 - 0.0024 18.1 2.6 0.017 15.3 0.3 2.4 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain XPG_I PF00867.18 KRH94937.1 - 3.3e-11 43.4 1.2 4.1e-10 39.9 0.0 3.4 3 1 0 3 3 3 1 XPG I-region XPG_N PF00752.17 KRH94937.1 - 2.8e-10 40.5 0.1 1.4e-09 38.3 0.1 2.3 1 1 0 1 1 1 1 XPG N-terminal domain Syntaxin-6_N PF09177.11 KRH94937.1 - 0.035 14.7 0.8 0.035 14.7 0.8 2.7 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Arg_repressor PF01316.21 KRH94937.1 - 0.04 13.7 0.2 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain DUF4768 PF15989.5 KRH94937.1 - 0.046 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) DUF745 PF05335.13 KRH94937.1 - 0.049 13.4 0.5 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) XPG_I_2 PF12813.7 KRH94937.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 XPG domain containing HTH_23 PF13384.6 KRH94938.1 - 3.2e-07 29.9 0.6 1.7e-06 27.6 0.4 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.6 KRH94938.1 - 0.00022 21.0 0.2 0.00065 19.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 KRH94938.1 - 0.00071 20.1 0.0 0.0025 18.4 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KRH94938.1 - 0.00072 19.5 1.9 0.0034 17.4 0.2 2.6 3 1 0 3 3 3 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KRH94938.1 - 0.003 17.2 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 PAX PF00292.18 KRH94938.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Sigma54_DBD PF04552.13 KRH94938.1 - 0.025 14.3 0.1 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54, DNA binding domain Sigma70_r4 PF04545.16 KRH94938.1 - 0.036 13.6 0.2 0.12 11.9 0.2 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 FAM184 PF15665.5 KRH94938.1 - 0.046 13.5 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HTH_Tnp_ISL3 PF13542.6 KRH94938.1 - 0.046 13.1 0.3 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_ECF PF07638.11 KRH94938.1 - 0.052 13.4 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 ECF sigma factor HTH_38 PF13936.6 KRH94938.1 - 0.063 13.1 1.6 0.14 11.9 1.6 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 KRH94938.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF3603 PF12227.8 KRH94938.1 - 0.067 12.5 0.1 0.35 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3603) PG_binding_1 PF01471.18 KRH94943.1 - 0.064 13.5 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF5490 PF17593.2 KRH94944.1 - 0.014 15.4 0.9 0.034 14.1 0.3 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5490) RNA_pol_Rpb1_1 PF04997.12 KRH94948.1 - 9e-95 317.6 2.7 9e-95 317.6 2.7 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KRH94948.1 - 4.3e-67 225.5 0.0 4.3e-67 225.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KRH94948.1 - 1.3e-44 151.9 0.3 3.1e-44 150.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KRH94948.1 - 4e-06 26.7 21.8 0.00028 20.8 0.5 3.9 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 4 Mucin PF01456.17 KRH94948.1 - 2 8.4 13.6 0.26 11.3 8.4 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L36e PF01158.18 KRH94949.1 - 1.3e-15 57.4 3.8 1.6e-15 57.1 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Aminotran_1_2 PF00155.21 KRH94950.1 - 2.9e-06 26.7 2.2 0.028 13.6 0.0 4.8 5 0 0 5 5 5 4 Aminotransferase class I and II GATA PF00320.27 KRH94951.1 - 5.4e-10 38.7 6.3 5.4e-10 38.7 6.3 2.6 3 0 0 3 3 3 1 GATA zinc finger DZR PF12773.7 KRH94951.1 - 0.015 15.3 14.0 0.21 11.7 6.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 KRH94951.1 - 1.4 9.2 10.5 3.9 7.8 1.4 2.7 2 2 0 2 2 2 0 zinc-ribbon Thioredoxin PF00085.20 KRH94952.1 - 1.3e-16 60.4 0.2 5.7e-13 48.8 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KRH94952.1 - 1.1e-11 45.0 3.3 0.00022 21.2 0.1 3.5 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KRH94952.1 - 4.5e-07 30.3 0.4 0.00054 20.4 0.2 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KRH94952.1 - 0.00021 21.6 0.7 0.015 15.6 0.1 3.7 2 2 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KRH94952.1 - 0.01 15.8 0.1 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 AhpC/TSA family zf-AN1 PF01428.16 KRH94956.1 - 1.2e-07 31.8 14.5 2.2e-07 30.9 14.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ribosomal_S17e PF00833.18 KRH94957.1 - 2e-34 118.1 2.4 2.4e-34 117.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ricin_B_lectin PF00652.22 KRH94958.1 - 0.0095 16.2 0.5 0.016 15.5 0.5 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Botulinum_HA-17 PF05588.11 KRH94958.1 - 0.044 13.9 1.6 0.38 10.9 0.1 2.6 1 1 2 3 3 3 0 Clostridium botulinum HA-17 domain Inhibitor_I66 PF16850.5 KRH94958.1 - 0.073 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase inhibitor I66 Toxin-deaminase PF14424.6 KRH94959.1 - 0.012 15.7 0.2 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases GCS PF03074.16 KRH94961.1 - 1.6e-47 162.6 2.2 2.4e-34 119.3 4.9 2.6 2 0 0 2 2 2 2 Glutamate-cysteine ligase Phage_int_SAM_5 PF13102.6 KRH94962.1 - 1.1 9.6 5.9 0.99 9.8 0.4 2.7 3 0 0 3 3 3 0 Phage integrase SAM-like domain T6PP_N PF18572.1 KRH94965.1 - 0.029 14.2 11.7 24 4.9 11.7 2.9 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Top6b_C PF18000.1 KRH94965.1 - 0.039 14.1 2.0 0.048 13.8 2.0 1.1 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF2733 PF10813.8 KRH94965.1 - 0.062 13.1 16.1 56 3.6 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF2733) Dodecin PF07311.12 KRH94965.1 - 0.16 12.2 3.1 87 3.5 0.0 3.5 2 1 3 5 5 5 0 Dodecin DUF4655 PF15548.6 KRH94965.1 - 0.26 10.2 0.0 0.27 10.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Bact_lectin PF18483.1 KRH94965.1 - 0.47 10.4 3.1 28 4.7 3.1 3.0 1 1 0 1 1 1 0 Bacterial lectin PRD PF00874.20 KRH94965.1 - 1.4 9.3 20.2 15 6.0 13.0 2.7 1 1 1 2 2 2 0 PRD domain DUF916 PF06030.12 KRH94965.1 - 3.7 7.6 11.1 8.4 6.5 2.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF916) DNA_pol_B_3 PF08408.10 KRH94965.1 - 4.6 7.4 11.8 38 4.5 5.4 3.1 1 1 1 2 2 2 0 DNA polymerase family B viral insert KH_dom-like PF14714.6 KRH94965.1 - 9 6.7 11.7 22 5.5 0.9 2.9 1 1 2 3 3 3 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Adap_comp_sub PF00928.21 KRH94966.1 - 1.1e-14 54.5 16.2 3.6e-14 52.8 16.2 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DNA_pol3_a_NII PF11490.8 KRH94967.1 - 0.015 15.2 1.8 0.016 15.1 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II AAA PF00004.29 KRH94968.1 - 2.2e-14 54.0 0.0 2.2e-14 54.0 0.0 3.5 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KRH94968.1 - 4.8e-13 49.2 2.5 2.9e-10 40.1 2.2 3.2 3 1 1 4 4 4 2 DNA polymerase III, delta subunit AAA_22 PF13401.6 KRH94968.1 - 2.8e-05 24.4 13.1 7.9e-05 22.9 1.0 4.2 3 2 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KRH94968.1 - 0.00019 21.4 0.1 0.00019 21.4 0.1 3.3 3 2 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KRH94968.1 - 0.0034 17.7 2.6 0.0034 17.7 2.6 2.2 1 1 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KRH94968.1 - 0.0037 17.1 22.0 0.0037 17.1 22.0 4.0 1 1 1 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KRH94968.1 - 0.0078 16.0 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KRH94968.1 - 0.0079 15.9 0.0 0.042 13.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KRH94968.1 - 0.0079 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KRH94968.1 - 0.008 16.6 11.0 0.17 12.3 10.9 3.2 1 1 0 1 1 1 1 AAA ATPase domain Rep_fac_C PF08542.11 KRH94968.1 - 0.0096 16.3 0.6 0.048 14.1 0.0 2.5 3 0 0 3 3 1 1 Replication factor C C-terminal domain AAA_30 PF13604.6 KRH94968.1 - 0.017 14.8 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRH94968.1 - 0.019 15.3 0.8 0.11 12.8 0.2 2.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KRH94968.1 - 0.021 14.6 0.5 0.96 9.2 0.1 2.7 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 KRH94968.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 KRH94968.1 - 0.039 14.3 82.7 1 9.7 26.2 4.0 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) NACHT PF05729.12 KRH94968.1 - 0.041 13.8 0.2 0.63 9.9 0.2 2.5 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 KRH94968.1 - 0.042 13.2 0.0 1.3 8.3 0.0 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KRH94968.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KRH94968.1 - 0.095 13.1 0.6 0.76 10.2 0.2 2.7 1 1 1 2 2 2 0 RNA helicase DUF4407 PF14362.6 KRH94968.1 - 5.5 6.2 53.9 3.2 7.0 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) V-ATPase_C PF03223.15 KRH94969.1 - 2.9e-12 46.7 20.7 2e-07 30.8 7.2 2.5 2 1 0 2 2 2 2 V-ATPase subunit C Cpn60_TCP1 PF00118.24 KRH94973.1 - 1.4e-47 162.5 7.9 2.8e-23 82.3 0.2 3.0 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Presenilin PF01080.17 KRH94973.1 - 0.12 11.1 6.2 0.19 10.5 4.9 1.8 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 KRH94973.1 - 0.29 10.3 1.4 0.47 9.6 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4050 PF13259.6 KRH94974.1 - 1.9 8.8 6.9 1.6 9.0 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PTR2 PF00854.21 KRH94977.1 - 8e-15 54.6 3.1 8e-15 54.6 3.1 2.1 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 KRH94977.1 - 7.4e-10 38.3 22.0 1.8e-05 23.9 7.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Zip PF02535.22 KRH94977.1 - 5.9e-06 25.7 0.0 5.9e-06 25.7 0.0 2.5 3 0 0 3 3 3 1 ZIP Zinc transporter Herpes_LMP1 PF05297.11 KRH94977.1 - 0.00034 19.9 0.7 0.0026 17.0 0.0 2.2 2 0 0 2 2 2 1 Herpesvirus latent membrane protein 1 (LMP1) SpoIIIAH PF12685.7 KRH94977.1 - 0.00046 20.1 8.9 0.00063 19.6 8.9 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein CLN3 PF02487.17 KRH94977.1 - 0.0008 18.6 5.2 0.0008 18.6 5.2 2.2 2 1 0 2 2 2 1 CLN3 protein V_ATPase_I PF01496.19 KRH94977.1 - 0.0013 16.7 4.2 0.0013 16.7 4.2 2.0 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Mem_trans PF03547.18 KRH94977.1 - 0.0016 16.9 3.3 0.0035 15.8 3.1 1.6 1 1 0 1 1 1 1 Membrane transport protein MAP17 PF15807.5 KRH94977.1 - 0.0032 17.7 7.1 0.0069 16.6 7.1 1.6 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S49_N PF08496.10 KRH94977.1 - 0.0039 17.3 2.0 0.0067 16.5 2.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Spt20 PF12090.8 KRH94977.1 - 0.0044 16.7 9.2 0.0065 16.1 9.2 1.2 1 0 0 1 1 1 1 Spt20 family NPR3 PF03666.13 KRH94977.1 - 0.0053 15.6 7.9 0.0072 15.2 7.9 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 MMM1 PF10296.9 KRH94977.1 - 0.012 14.7 6.3 0.012 14.7 4.7 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 UPF0242 PF06785.11 KRH94977.1 - 0.013 15.7 1.6 0.013 15.7 1.6 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ctr PF04145.15 KRH94977.1 - 0.027 15.1 0.1 0.11 13.1 0.1 2.2 1 0 0 1 1 1 0 Ctr copper transporter family EOS1 PF12326.8 KRH94977.1 - 0.047 13.6 0.7 0.096 12.6 0.7 1.5 1 0 0 1 1 1 0 N-glycosylation protein Cadherin_C_2 PF16492.5 KRH94977.1 - 0.065 14.0 0.2 0.27 12.0 0.2 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Gti1_Pac2 PF09729.9 KRH94977.1 - 0.067 13.3 7.2 0.1 12.7 7.2 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 KRH94977.1 - 0.11 10.8 11.1 0.14 10.4 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4446 PF14584.6 KRH94977.1 - 0.14 12.1 1.4 0.33 10.9 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SLC12 PF03522.15 KRH94977.1 - 0.31 10.0 9.5 0.5 9.3 9.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 KRH94977.1 - 1.2 8.7 11.1 8.2 6.1 11.1 2.0 1 1 0 1 1 1 0 FAM176 family DUF4969 PF16339.5 KRH94977.1 - 2.8 8.4 4.8 0.7 10.3 0.1 2.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4969) AIF_C PF14721.6 KRH94977.1 - 3.1 8.2 11.1 0.059 13.7 1.5 2.1 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ALMT PF11744.8 KRH94977.1 - 3.7 6.3 8.3 6.2 5.5 8.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4471 PF14740.6 KRH94977.1 - 4.2 6.5 12.5 17 4.5 12.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) EphA2_TM PF14575.6 KRH94977.1 - 4.9 8.1 6.5 3.4 8.6 2.2 3.1 3 1 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain Connexin PF00029.19 KRH94977.1 - 5.9 6.6 17.8 0.12 12.1 8.8 2.7 2 1 0 2 2 2 0 Connexin Tmemb_9 PF05434.11 KRH94977.1 - 6.7 6.6 8.6 50 3.8 8.6 2.2 1 1 0 1 1 1 0 TMEM9 PTR2 PF00854.21 KRH94978.1 - 8.8e-11 41.3 1.9 8.8e-11 41.3 1.9 3.3 2 1 0 2 2 2 1 POT family Vpu PF00558.19 KRH94978.1 - 0.087 12.6 0.0 0.36 10.6 0.0 2.1 1 1 0 1 1 1 0 Vpu protein CPSF_A PF03178.15 KRH94979.1 - 0.001 18.5 0.1 0.0023 17.3 0.1 1.6 1 1 0 1 1 1 1 CPSF A subunit region BBS2_Mid PF14783.6 KRH94979.1 - 0.0033 17.4 0.0 0.3 11.2 0.0 2.9 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Rpr2 PF04032.16 KRH94979.1 - 0.033 14.5 0.1 0.058 13.7 0.1 1.3 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_28 PF00295.17 KRH94980.1 - 0.13 11.3 7.6 0.18 10.8 7.6 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 LRR_6 PF13516.6 KRH94980.1 - 0.46 10.7 11.7 31 5.0 0.1 4.9 3 2 0 4 4 4 0 Leucine Rich repeat Haemocyan_bet_s PF14830.6 KRH94981.1 - 0.037 14.0 0.1 0.047 13.7 0.1 1.1 1 0 0 1 1 1 0 Haemocyanin beta-sandwich DDE_Tnp_IS1595 PF12762.7 KRH94985.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Imm35 PF15567.6 KRH94991.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 35 PA28_alpha PF02251.18 KRH94992.1 - 0.039 14.0 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit RVT_1 PF00078.27 KRH94993.1 - 3.3e-07 30.0 0.1 4.9e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 KRH94995.1 - 1.5e-05 24.7 0.1 2.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 KRH94995.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1726 PF08351.11 KRH94995.1 - 0.078 12.9 0.0 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) ABC_tran PF00005.27 KRH94998.1 - 2.5e-22 79.9 0.0 4.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 KRH94998.1 - 0.00014 21.8 0.1 0.00035 20.5 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea SMC_N PF02463.19 KRH94998.1 - 0.0003 20.3 1.7 0.00097 18.6 1.7 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KRH94998.1 - 0.00031 21.0 0.1 0.0012 19.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 KRH94998.1 - 0.0015 19.1 2.8 0.0034 17.9 2.8 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH94998.1 - 0.0017 18.8 0.0 0.0029 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KRH94998.1 - 0.002 17.3 25.6 0.0035 16.5 25.6 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KRH94998.1 - 0.0029 17.5 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KRH94998.1 - 0.006 16.4 2.7 1.1 8.9 0.1 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KRH94998.1 - 0.0099 15.3 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_13 PF13166.6 KRH94998.1 - 0.015 14.0 1.6 0.068 11.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KRH94998.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KRH94998.1 - 0.015 15.7 0.1 0.096 13.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 KRH94998.1 - 0.017 14.8 0.2 0.037 13.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KRH94998.1 - 0.018 15.0 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KRH94998.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KRH94998.1 - 0.028 13.5 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KRH94998.1 - 0.029 14.4 1.0 0.42 10.7 0.1 3.0 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 KRH94998.1 - 0.037 14.6 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KRH94998.1 - 0.037 14.1 0.2 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KRH94998.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KRH94998.1 - 0.053 13.1 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KRH94998.1 - 0.057 13.8 2.0 0.77 10.2 1.4 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KRH94998.1 - 0.066 13.1 0.2 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 KRH94998.1 - 0.098 13.1 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KRH94998.1 - 0.17 12.2 0.1 0.48 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KRH94998.1 - 0.18 11.6 1.7 0.31 10.8 0.1 2.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KRH94998.1 - 0.3 11.1 1.1 0.71 9.9 0.5 2.0 2 1 0 2 2 2 0 Dynamin family DUF2427 PF10348.9 KRH94998.1 - 1.2 9.0 5.8 3.2 7.6 3.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) YIF1 PF03878.15 KRH94999.1 - 3.3e-05 23.5 24.1 0.016 14.7 24.1 3.1 1 1 0 1 1 1 1 YIF1 Plasmod_Pvs28 PF06247.11 KRH95000.1 - 0.029 14.7 42.2 12 6.3 6.8 7.3 1 1 4 5 5 5 0 Pvs28 EGF domain Imm59 PF15597.6 KRH95000.1 - 0.03 14.8 6.5 9.1 6.8 0.7 3.7 1 1 2 3 3 3 0 Immunity protein 59 GrpB PF04229.14 KRH95000.1 - 0.063 13.5 4.2 5.3 7.2 0.2 2.5 1 1 2 3 3 3 0 GrpB protein Spa1_C PF18218.1 KRH95000.1 - 0.086 13.3 2.4 13 6.3 0.2 2.4 1 1 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain Cadherin_2 PF08266.12 KRH95000.1 - 0.091 12.6 19.1 26 4.8 0.1 6.5 2 2 5 7 7 7 0 Cadherin-like LamB PF02264.15 KRH95000.1 - 3.3 7.5 5.9 28 4.4 1.1 2.9 1 1 0 2 2 2 0 LamB porin DUF3177 PF11375.8 KRH95000.1 - 6.8 6.4 11.3 9.9 5.9 0.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3177) Sen15 PF09631.10 KRH95001.1 - 0.088 13.1 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Sen15 protein Pex24p PF06398.11 KRH95005.1 - 0.046 12.7 0.4 0.051 12.6 0.4 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Rac1 PF09632.10 KRH95005.1 - 0.051 12.7 0.0 0.052 12.7 0.0 1.1 1 0 0 1 1 1 0 Rac1-binding domain SAP PF02037.27 KRH95006.1 - 1.4e-05 24.7 0.0 3.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain rve PF00665.26 KRH95007.1 - 0.018 15.2 0.7 0.06 13.6 0.7 1.9 1 1 0 1 1 1 0 Integrase core domain MAP17 PF15807.5 KRH95012.1 - 0.027 14.7 0.5 0.037 14.3 0.5 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CLN3 PF02487.17 KRH95012.1 - 0.18 10.8 0.3 0.19 10.8 0.3 1.0 1 0 0 1 1 1 0 CLN3 protein DUF4834 PF16118.5 KRH95012.1 - 0.48 11.4 5.9 0.94 10.5 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 KRH95013.1 - 0.013 14.3 6.2 0.017 13.9 6.2 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KRH95013.1 - 0.015 14.5 0.5 0.02 14.1 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 KRH95013.1 - 0.023 13.0 3.8 0.028 12.7 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 KRH95013.1 - 0.026 13.6 6.1 0.036 13.1 6.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 KRH95013.1 - 0.2 10.2 10.1 0.23 10.0 10.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4574 PF15141.6 KRH95013.1 - 0.47 10.4 2.3 1.7 8.6 0.0 2.3 1 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 MMU163 PF17119.5 KRH95013.1 - 0.86 8.7 6.7 1.7 7.8 6.7 1.5 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Menin PF05053.13 KRH95013.1 - 5.5 5.2 8.7 7.8 4.7 8.7 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 KRH95014.1 - 2e-25 89.7 1.2 2e-15 56.9 0.3 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KRH95014.1 - 1.2e-12 47.7 0.1 1.2e-11 44.4 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH95014.1 - 0.0029 17.0 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KRH95014.1 - 0.0035 16.2 0.5 0.0067 15.2 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase Glyco_hydro_7 PF00840.20 KRH95014.1 - 0.079 11.7 0.6 0.12 11.0 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 TcdB_N PF12918.7 KRH95015.1 - 0.0027 18.0 1.2 0.0085 16.4 0.2 2.3 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain Aspzincin_M35 PF14521.6 KRH95015.1 - 0.041 14.4 0.8 0.08 13.5 0.2 1.9 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase PIF1 PF05970.14 KRH95015.1 - 0.067 12.3 0.6 0.098 11.8 0.1 1.5 2 0 0 2 2 2 0 PIF1-like helicase RepA_C PF04796.12 KRH95015.1 - 0.2 11.7 0.4 4.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Plasmid encoded RepA protein dUTPase PF00692.19 KRH95016.1 - 1.7e-14 53.6 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase MIF4G PF02854.19 KRH95017.1 - 2.1e-14 53.7 8.2 2.1e-14 53.7 8.2 2.0 2 0 0 2 2 2 1 MIF4G domain UvdE PF03851.14 KRH95017.1 - 0.00099 18.4 0.2 0.0028 16.9 0.2 1.8 1 0 0 1 1 1 1 UV-endonuclease UvdE SHP PF03579.13 KRH95020.1 - 0.018 15.0 1.3 0.021 14.8 1.3 1.1 1 0 0 1 1 1 0 Small hydrophobic protein Cytochrom_B561 PF03188.16 KRH95020.1 - 0.041 14.0 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Lig_chan PF00060.26 KRH95020.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel Baculo_11_kDa PF06143.11 KRH95020.1 - 0.4 10.3 2.9 0.38 10.3 2.0 1.5 1 1 1 2 2 2 0 Baculovirus 11 kDa family Methyltransf_4 PF02390.17 KRH95021.1 - 1.2e-39 135.5 1.3 1.6e-38 131.9 1.3 2.0 1 1 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 KRH95021.1 - 0.0031 17.1 0.0 0.006 16.2 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 KRH95021.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 KRH95021.1 - 0.011 15.5 0.1 0.036 13.9 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain RhoGEF67_u2 PF16614.5 KRH95021.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Methyltransf_12 PF08242.12 KRH95021.1 - 0.034 14.9 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KRH95021.1 - 0.035 13.9 0.0 0.27 11.0 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain MTS PF05175.14 KRH95021.1 - 0.063 12.8 0.0 0.33 10.5 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KRH95021.1 - 0.11 13.2 0.0 0.22 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KRH95021.1 - 0.13 12.9 0.0 0.4 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L22e PF01776.17 KRH95022.1 - 1.8e-27 95.8 2.2 2.7e-27 95.3 2.2 1.3 1 0 0 1 1 1 1 Ribosomal L22e protein family Cys_rich_KTR PF14205.6 KRH95022.1 - 0.051 13.4 0.4 0.13 12.1 0.4 1.7 1 1 0 1 1 1 0 Cysteine-rich KTR PBS_linker_poly PF00427.21 KRH95022.1 - 0.066 13.2 0.2 0.086 12.9 0.2 1.2 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Yippee-Mis18 PF03226.14 KRH95022.1 - 0.096 12.9 1.2 2.8 8.2 0.0 2.1 1 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.25 KRH95023.1 - 6.1e-53 179.9 6.7 7.6e-53 179.6 6.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH95023.1 - 6.9e-41 140.2 1.6 8.6e-41 139.9 1.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KRH95023.1 - 9.7e-07 27.9 1.0 1.5e-06 27.3 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KRH95023.1 - 0.0011 18.3 0.2 0.019 14.3 0.2 2.3 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KRH95023.1 - 0.011 15.4 1.5 0.22 11.1 0.6 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KRH95023.1 - 0.21 11.5 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cation_efflux PF01545.21 KRH95024.1 - 6.8e-39 133.7 18.1 8.1e-39 133.4 18.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2070 PF09843.9 KRH95024.1 - 0.01 14.2 7.9 0.016 13.5 7.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ZT_dimer PF16916.5 KRH95024.1 - 0.032 14.3 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter CrgA PF06781.12 KRH95024.1 - 0.12 12.4 0.4 0.12 12.4 0.4 2.2 2 1 0 2 2 2 0 Cell division protein CrgA Ndc1_Nup PF09531.10 KRH95025.1 - 0.37 9.4 1.5 0.37 9.4 1.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA-synt_1c PF00749.21 KRH95026.1 - 5.2e-92 308.1 0.5 8.3e-92 307.4 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KRH95026.1 - 5.3e-14 52.5 0.1 1.4e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KRH95026.1 - 0.015 16.2 1.0 0.036 15.0 1.0 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF382 PF04037.13 KRH95027.1 - 9.5e-08 32.3 1.5 9.5e-08 32.3 1.5 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF382) DarA_C PF18789.1 KRH95027.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 Defence against restriction A C-terminal HTH_23 PF13384.6 KRH95029.1 - 1e-05 25.2 0.0 0.00012 21.8 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain TrmB PF01978.19 KRH95029.1 - 4.8e-05 23.2 0.0 0.0069 16.2 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_33 PF13592.6 KRH95029.1 - 9.7e-05 21.9 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KRH95029.1 - 0.00011 22.3 0.0 0.0092 16.1 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KRH95029.1 - 0.00011 21.7 0.0 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 KRH95029.1 - 0.00024 20.7 0.1 0.00068 19.3 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_32 PF13565.6 KRH95029.1 - 0.0022 18.5 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KRH95029.1 - 0.02 14.9 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Knl1_RWD_C PF18210.1 KRH95029.1 - 0.021 15.3 0.1 0.034 14.6 0.1 1.4 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain Sigma70_r4 PF04545.16 KRH95029.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.12 KRH95029.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.6 KRH95029.1 - 0.041 13.7 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF722 PF05263.11 KRH95029.1 - 0.047 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) HTH_IclR PF09339.10 KRH95029.1 - 0.051 13.4 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Phage_AlpA PF05930.12 KRH95029.1 - 0.072 12.9 0.1 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_40 PF14493.6 KRH95029.1 - 0.13 12.7 0.0 0.48 10.9 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KRH95029.1 - 0.14 12.3 1.2 4.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 KRH95029.1 - 0.16 11.7 0.5 21 4.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.6 KRH95030.1 - 1.7e-08 34.3 0.2 2.3e-08 33.9 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Adhesin_P1_N PF18652.1 KRH95034.1 - 0.085 12.9 2.0 0.13 12.3 2.0 1.3 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain MLVIN_C PF18697.1 KRH95035.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain T4_baseplate PF12322.8 KRH95036.1 - 0.0025 17.3 0.3 0.0026 17.2 0.3 1.0 1 0 0 1 1 1 1 T4 bacteriophage base plate protein DNA_ligase_ZBD PF03119.16 KRH95036.1 - 0.11 12.5 0.7 0.18 11.9 0.7 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain ABC_tran PF00005.27 KRH95043.1 - 4.7e-22 79.0 0.0 1e-21 77.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KRH95043.1 - 2e-07 31.1 1.1 0.0018 18.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 KRH95043.1 - 9.6e-07 28.4 12.8 9.6e-07 28.4 12.8 3.1 2 1 0 3 3 3 1 ABC-2 type transporter AAA_23 PF13476.6 KRH95043.1 - 3.4e-05 24.5 4.5 0.00039 21.0 4.6 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KRH95043.1 - 0.00026 20.5 0.8 0.007 15.8 0.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KRH95043.1 - 0.00042 20.6 0.3 0.0021 18.4 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KRH95043.1 - 0.00088 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KRH95043.1 - 0.0045 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KRH95043.1 - 0.0067 16.8 3.0 0.027 14.9 0.8 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KRH95043.1 - 0.015 15.9 0.3 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KRH95043.1 - 0.017 15.4 0.8 0.047 13.9 0.8 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRH95043.1 - 0.017 14.8 1.1 0.042 13.6 1.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KRH95043.1 - 0.019 15.0 0.4 0.019 15.0 0.4 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KRH95043.1 - 0.025 14.6 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KRH95043.1 - 0.034 14.2 1.5 0.06 13.4 0.1 2.1 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 KRH95043.1 - 0.036 14.0 0.2 0.075 12.9 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KRH95043.1 - 0.054 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KRH95043.1 - 0.056 13.4 0.7 0.23 11.3 0.2 2.2 2 1 0 2 2 2 0 NTPase T2SSE PF00437.20 KRH95043.1 - 0.059 12.4 0.9 0.14 11.2 0.9 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein VAPB_antitox PF02697.14 KRH95043.1 - 0.065 14.0 1.0 0.15 12.8 1.0 1.6 1 0 0 1 1 1 0 Putative antitoxin AAA_33 PF13671.6 KRH95043.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KRH95043.1 - 0.079 12.5 0.6 0.23 11.1 0.6 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KRH95043.1 - 0.081 12.7 1.2 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KRH95043.1 - 0.1 12.9 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cu_amine_oxidN1 PF07833.11 KRH95045.1 - 0.14 12.7 0.2 0.52 10.8 0.0 2.2 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain MazE_antitoxin PF04014.18 KRH95051.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin MazE_antitoxin PF04014.18 KRH95052.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF1878 PF08963.10 KRH95054.1 - 0.61 10.6 5.4 0.25 11.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) SSrecog PF03531.14 KRH95054.1 - 0.92 9.5 4.2 0.38 10.7 1.0 2.1 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) PSI_integrin PF17205.3 KRH95055.1 - 0.03 14.0 1.2 0.03 14.0 1.2 2.5 3 0 0 3 3 3 0 Integrin plexin domain DUF4804 PF16062.5 KRH95055.1 - 0.046 12.5 1.3 1.2 7.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4804) Helicase_C PF00271.31 KRH95058.1 - 2.6e-14 53.5 1.1 2.3e-10 40.8 0.0 3.6 3 1 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.23 KRH95058.1 - 9.3e-14 50.9 0.2 1.7e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDP-OH_P_transf PF01066.21 KRH95059.1 - 3.8e-17 62.8 0.3 3.8e-17 62.8 0.3 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HA2 PF04408.23 KRH95060.1 - 6.7e-13 48.9 0.0 3e-12 46.8 0.0 2.2 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KRH95060.1 - 4.2e-12 46.4 1.1 1.3e-11 44.8 1.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KRH95060.1 - 4.8e-09 36.2 0.0 1.3e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 KRH95060.1 - 0.00085 19.7 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KRH95060.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KRH95060.1 - 0.0022 18.3 0.0 0.0073 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KRH95060.1 - 0.0023 18.3 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold SRPRB PF09439.10 KRH95060.1 - 0.014 14.8 0.3 2 7.8 0.0 2.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 KRH95060.1 - 0.02 14.9 4.8 0.04 13.9 0.2 3.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit YjhX_toxin PF09857.9 KRH95060.1 - 0.077 13.0 0.1 0.59 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair AAA_23 PF13476.6 KRH95060.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_14 PF13173.6 KRH95060.1 - 0.37 10.8 3.4 1.8 8.6 0.3 3.4 2 1 0 2 2 2 0 AAA domain eIF2A PF08662.11 KRH95061.1 - 7.7e-29 100.9 2.3 8.2e-29 100.9 0.4 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KRH95061.1 - 0.037 13.1 0.7 0.13 11.3 0.1 2.0 1 1 1 2 2 2 0 Coatomer WD associated region EIF_2_alpha PF07541.12 KRH95064.1 - 1.5e-23 83.1 4.5 1.5e-23 83.1 4.5 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KRH95064.1 - 2.9e-08 33.9 1.1 6.1e-08 32.9 1.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HI0933_like PF03486.14 KRH95064.1 - 0.11 11.2 0.1 0.26 9.9 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein TBX PF12598.8 KRH95064.1 - 0.34 11.7 4.5 0.74 10.7 0.7 2.4 2 0 0 2 2 2 0 T-box transcription factor Med18 PF09637.10 KRH95066.1 - 0.00073 19.4 0.1 0.007 16.2 0.0 2.4 2 1 1 3 3 3 1 Med18 protein DUF4136 PF13590.6 KRH95066.1 - 0.0093 16.5 0.4 0.021 15.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4136) FERM_f0 PF16511.5 KRH95066.1 - 0.099 13.0 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM RNA_pol_Rpb2_6 PF00562.28 KRH95068.1 - 5.2e-130 434.0 0.6 7e-130 433.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KRH95068.1 - 4e-58 196.3 0.2 6.4e-58 195.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KRH95068.1 - 5.5e-41 140.3 1.0 9.4e-41 139.5 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KRH95068.1 - 2.5e-31 107.9 0.2 7.9e-31 106.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KRH95068.1 - 1.8e-27 95.3 0.0 3.8e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KRH95068.1 - 8.9e-21 74.0 0.1 2.5e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KRH95068.1 - 2.7e-18 66.2 3.5 1.1e-17 64.3 3.5 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zn-ribbon_14 PF16503.5 KRH95068.1 - 3.4 7.3 6.7 1.6 8.3 3.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon zf-RING_2 PF13639.6 KRH95069.1 - 8.9e-12 45.1 8.8 1.7e-11 44.3 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KRH95069.1 - 7.7e-09 35.3 9.3 1.4e-08 34.4 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KRH95069.1 - 9.1e-09 34.9 1.5 1.8e-08 34.0 1.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KRH95069.1 - 1.3e-07 31.8 8.4 2.6e-07 30.8 8.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KRH95069.1 - 3e-05 23.8 7.8 6e-05 22.8 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRH95069.1 - 0.0001 22.1 5.2 0.00016 21.4 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH95069.1 - 0.00011 22.1 6.3 0.00019 21.3 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KRH95069.1 - 0.00028 20.8 7.3 0.00064 19.7 7.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KRH95069.1 - 0.0015 18.6 4.3 0.003 17.6 4.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KRH95069.1 - 0.03 13.9 6.2 0.059 13.0 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KRH95069.1 - 0.073 13.3 4.7 0.15 12.2 4.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KRH95069.1 - 0.29 11.0 4.8 0.62 9.9 4.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KRH95069.1 - 0.8 9.6 6.2 1.4 8.8 6.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KRH95069.1 - 2 8.7 5.7 5.1 7.4 5.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KRH95069.1 - 2.1 8.4 6.6 4.6 7.4 6.6 1.6 1 0 0 1 1 1 0 Zinc-finger PHD PF00628.29 KRH95069.1 - 6.5 6.7 10.5 2.1 8.3 7.5 1.8 2 0 0 2 2 2 0 PHD-finger RINGv PF12906.7 KRH95069.1 - 9.4 6.5 8.4 21 5.4 8.4 1.6 1 0 0 1 1 1 0 RING-variant domain Ribosomal_L15e PF00827.17 KRH95070.1 - 1.8e-73 246.3 1.4 2.3e-73 246.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L15 RNA_pol_L_2 PF13656.6 KRH95071.1 - 1.1e-17 63.6 0.1 1.4e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KRH95071.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain LsmAD PF06741.13 KRH95072.1 - 1.2e-11 45.0 6.5 1.2e-11 45.0 6.5 2.9 2 1 0 2 2 2 1 LsmAD domain FtsJ PF01728.19 KRH95073.1 - 2.9e-54 183.9 0.1 5.3e-54 183.0 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KRH95073.1 - 1.3e-10 41.4 8.1 1.3e-10 41.4 8.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3381) Spb1_C PF07780.12 KRH95073.1 - 0.0034 17.1 12.7 0.0034 17.1 12.7 3.2 2 1 1 3 3 3 2 Spb1 C-terminal domain Methyltransf_23 PF13489.6 KRH95073.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KRH95073.1 - 0.027 15.2 0.6 0.15 12.8 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain Sod_Fe_C PF02777.18 KRH95075.1 - 3.6e-30 104.1 0.4 7.1e-30 103.2 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KRH95075.1 - 2.9e-24 85.4 3.4 4.8e-24 84.6 3.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNA_POL_M_15KD PF02150.16 KRH95078.1 - 7.2e-08 32.2 2.0 7.2e-08 32.2 2.0 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KRH95078.1 - 0.0014 18.4 3.3 0.0014 18.4 3.3 3.1 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) zf_C2H2_13 PF18508.1 KRH95078.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.5 3 0 0 3 3 2 1 Zinc finger domain DZR PF12773.7 KRH95078.1 - 0.0049 16.9 9.6 0.042 13.9 0.5 2.5 2 1 0 2 2 2 2 Double zinc ribbon Ogr_Delta PF04606.12 KRH95078.1 - 0.018 15.0 4.1 0.11 12.5 0.4 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 KRH95078.1 - 0.062 12.9 8.1 0.068 12.8 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4524 PF15025.6 KRH95078.1 - 0.089 12.5 0.2 0.12 12.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4524) NMD3 PF04981.13 KRH95078.1 - 0.13 11.7 9.1 0.22 11.0 1.9 2.1 1 1 0 2 2 2 0 NMD3 family zf-ribbon_3 PF13248.6 KRH95078.1 - 0.2 11.1 0.3 0.2 11.1 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KRH95078.1 - 0.27 11.4 11.6 0.81 9.9 2.9 3.2 2 2 1 3 3 3 0 Zinc ribbon domain zf-C2H2 PF00096.26 KRH95078.1 - 0.56 10.8 0.1 0.56 10.8 0.1 3.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.6 KRH95078.1 - 1.2 9.7 6.9 1.2 9.7 2.8 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.6 KRH95078.1 - 1.3 9.0 12.9 4.7 7.2 0.3 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 KRH95078.1 - 1.4 10.0 0.1 1.4 10.0 0.1 3.5 4 0 0 4 4 3 0 C2H2-type zinc finger Nudix_N_2 PF14803.6 KRH95078.1 - 1.5 8.8 14.5 0.29 11.1 1.9 3.3 2 2 0 2 2 2 0 Nudix N-terminal zf-SNAP50_C PF12251.8 KRH95078.1 - 2.2 7.9 15.5 1.1 8.9 7.9 2.8 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Lar_restr_allev PF14354.6 KRH95078.1 - 2.5 8.5 10.7 6.2 7.3 5.2 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_17 PF17120.5 KRH95078.1 - 3 7.5 11.1 4.1 7.1 0.1 3.4 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type Fip1 PF05182.13 KRH95079.1 - 6.6e-23 79.9 2.3 1.2e-22 79.1 2.3 1.5 1 0 0 1 1 1 1 Fip1 motif CTD_bind PF04818.13 KRH95080.1 - 0.47 11.3 2.9 0.5 11.2 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase II-binding domain. TPP1 PF10341.9 KRH95082.1 - 2e-07 30.9 0.5 5.9e-06 26.2 0.1 3.1 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD Med27 PF11571.8 KRH95082.1 - 1.1 9.6 3.6 1.2 9.6 0.0 2.9 2 1 1 3 3 3 0 Mediator complex subunit 27 Ribosomal_L12_N PF16320.5 KRH95082.1 - 3.9 7.3 5.1 11 5.8 0.3 2.9 1 1 1 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain XPG_I PF00867.18 KRH95084.1 - 3.7e-13 49.6 1.5 1.5e-12 47.7 0.0 2.8 3 1 0 3 3 3 1 XPG I-region XPG_N PF00752.17 KRH95084.1 - 1.6e-10 41.4 0.4 1.9e-08 34.7 0.1 2.8 2 1 0 2 2 2 1 XPG N-terminal domain Vps54_N PF10475.9 KRH95086.1 - 0.78 9.0 11.6 0.11 11.7 5.6 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Motile_Sperm PF00635.26 KRH95088.1 - 5e-15 55.3 0.1 6.9e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF5572 PF17733.1 KRH95088.1 - 0.043 13.7 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5572) Condensin2nSMC PF12422.8 KRH95088.1 - 0.063 13.5 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit TPR_1 PF00515.28 KRH95089.1 - 0.057 13.3 0.4 0.15 11.9 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HATPase_c PF02518.26 KRH95091.1 - 0.0022 18.5 2.7 0.0056 17.2 0.6 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDT PF02791.17 KRH95092.1 - 0.017 15.4 0.2 0.05 13.9 0.2 1.8 1 0 0 1 1 1 0 DDT domain Cnl2_NKP2 PF09447.10 KRH95092.1 - 0.04 14.1 0.5 0.17 12.1 0.2 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein IpaB_EvcA PF03278.13 KRH95092.1 - 1.6 8.4 7.9 0.1 12.3 0.3 2.6 3 0 0 3 3 3 0 IpaB/EvcA family ApoB100_C PF12491.8 KRH95093.1 - 0.024 14.6 0.1 0.052 13.5 0.1 1.6 1 1 1 2 2 2 0 Apolipoprotein B100 C terminal SH PF01445.17 KRH95093.1 - 0.14 12.2 1.4 0.17 11.8 1.4 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein ATP-synt_8 PF00895.20 KRH95093.1 - 0.39 11.2 2.7 0.38 11.3 1.9 1.4 1 1 0 1 1 1 0 ATP synthase protein 8 DNA_pol3_delta2 PF13177.6 KRH95094.1 - 5.6e-08 32.7 0.1 0.00013 21.8 0.0 3.2 2 1 0 3 3 3 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KRH95094.1 - 1.5e-05 24.5 0.4 0.027 13.9 0.1 2.9 1 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 KRH95094.1 - 1.9e-05 25.1 1.5 0.0026 18.2 0.2 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH95094.1 - 0.00098 19.1 0.3 0.35 10.8 0.1 2.9 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KRH95094.1 - 0.0012 18.9 3.6 0.091 12.8 0.2 3.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KRH95094.1 - 0.0019 18.6 0.1 0.037 14.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KRH95094.1 - 0.0029 17.9 0.4 0.13 12.5 0.2 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KRH95094.1 - 0.0098 15.6 0.0 3.5 7.3 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 KRH95094.1 - 0.014 15.2 0.0 0.082 12.7 0.0 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KRH95094.1 - 0.015 14.7 0.1 1.1 8.7 0.1 2.4 1 1 1 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KRH95094.1 - 0.016 14.9 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KRH95094.1 - 0.024 15.2 0.4 0.14 12.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KRH95094.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KRH95094.1 - 0.068 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KRH95094.1 - 0.093 12.9 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KRH95094.1 - 0.095 12.7 0.1 0.67 9.9 0.0 2.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KRH95094.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.2 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 KRH95094.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RMMBL PF07521.12 KRH95095.1 - 3.9e-12 45.9 0.2 2e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KRH95095.1 - 2.4e-09 36.9 0.9 2.2e-08 33.8 0.4 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 KRH95095.1 - 7.3e-08 32.7 0.0 7.3e-08 32.7 0.0 2.9 3 2 0 3 3 3 1 Beta-Casp domain Lactamase_B PF00753.27 KRH95095.1 - 1.1e-06 28.8 0.0 4.8e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KRH95095.1 - 0.00017 21.1 0.0 0.0033 17.0 0.0 2.8 3 0 0 3 3 3 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KRH95095.1 - 0.0093 16.1 0.1 0.0093 16.1 0.1 2.6 3 0 0 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_3 PF13483.6 KRH95095.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Beta-lactamase superfamily domain BUD22 PF09073.10 KRH95095.1 - 0.76 9.1 36.8 1.5 8.1 36.8 1.5 1 0 0 1 1 1 0 BUD22 Ribosomal_L7Ae PF01248.26 KRH95096.1 - 1.2e-06 28.1 0.6 1.6e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GSAP-16 PF14959.6 KRH95097.1 - 0.042 13.7 0.5 0.13 12.1 0.5 1.9 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term CPSF_A PF03178.15 KRH95098.1 - 1.8e-29 103.1 0.7 4.1e-23 82.2 0.1 2.7 3 0 0 3 3 3 2 CPSF A subunit region YjeF_N PF03853.15 KRH95100.1 - 1.3e-21 77.2 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus SLD5_C PF16922.5 KRH95101.1 - 4.9e-05 23.4 0.1 8.1e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus 14-3-3 PF00244.20 KRH95101.1 - 0.0088 15.6 3.2 0.011 15.2 3.2 1.1 1 0 0 1 1 1 1 14-3-3 protein BBS2_Mid PF14783.6 KRH95102.1 - 0.0016 18.4 0.3 0.21 11.6 0.1 2.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Beta_lactamase3 PF17030.5 KRH95103.1 - 2.5e-43 147.8 6.3 2.5e-43 147.8 6.3 2.5 2 1 0 2 2 2 1 Putative beta-lactamase-like family E2F_TDP PF02319.20 KRH95105.1 - 2e-16 59.8 0.0 1.2e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 KRH95105.1 - 3.7e-14 52.9 0.8 9e-14 51.6 0.8 1.6 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain B-block_TFIIIC PF04182.12 KRH95105.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TrmB PF01978.19 KRH95105.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 KRH95105.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Nic96 PF04097.14 KRH95106.1 - 2.3e-17 62.7 2.3 3e-14 52.4 0.9 2.2 2 0 0 2 2 2 2 Nup93/Nic96 Vps39_1 PF10366.9 KRH95106.1 - 1.7 8.9 10.9 0.62 10.4 2.1 3.8 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 1 HUN PF08729.10 KRH95107.1 - 1.2 9.2 5.5 0.2 11.7 1.4 1.9 2 0 0 2 2 2 0 HPC2 and ubinuclein domain AAA PF00004.29 KRH95111.1 - 5.6e-39 133.6 0.3 2.5e-38 131.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KRH95111.1 - 1.1e-08 34.9 0.0 3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KRH95111.1 - 1.9e-07 30.7 0.0 2.5e-06 27.2 0.0 2.5 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KRH95111.1 - 4.6e-07 29.9 0.3 0.0035 17.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KRH95111.1 - 2.1e-06 28.0 0.7 0.0047 17.2 0.1 3.6 3 1 1 4 4 3 1 AAA domain RuvB_N PF05496.12 KRH95111.1 - 2.8e-06 27.1 0.0 3.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KRH95111.1 - 0.00022 21.4 2.1 0.0015 18.7 0.0 2.7 2 2 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KRH95111.1 - 0.00063 19.8 0.1 0.0079 16.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KRH95111.1 - 0.001 19.5 0.2 0.041 14.3 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KRH95111.1 - 0.0018 17.6 0.1 0.0069 15.6 0.0 2.0 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KRH95111.1 - 0.0062 15.9 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KRH95111.1 - 0.0064 16.4 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KRH95111.1 - 0.022 15.2 0.0 0.064 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KRH95111.1 - 0.024 14.1 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region XRN_M PF17846.1 KRH95111.1 - 0.037 13.0 1.5 0.062 12.3 1.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain IstB_IS21 PF01695.17 KRH95111.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KRH95111.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KRH95111.1 - 0.071 13.7 1.1 0.19 12.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KRH95111.1 - 0.1 12.2 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KRH95111.1 - 0.12 12.1 2.5 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KRH95111.1 - 0.13 12.5 0.0 0.59 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KRH95111.1 - 0.17 11.8 0.3 3.1 7.7 0.1 2.7 1 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 KRH95111.1 - 0.19 12.3 0.0 0.19 12.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter RINGv PF12906.7 KRH95112.1 - 8.3e-09 35.4 1.6 8.3e-09 35.4 1.6 1.6 2 0 0 2 2 2 1 RING-variant domain LSM PF01423.22 KRH95113.1 - 5.8e-10 38.7 0.4 7.7e-10 38.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KRH95113.1 - 0.024 14.7 0.4 1.1 9.4 0.4 2.0 1 1 0 1 1 1 0 Scd6-like Sm domain TFIIS_C PF01096.18 KRH95114.1 - 1.8e-16 59.7 1.8 1.8e-16 59.7 1.8 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-C4_Topoisom PF01396.19 KRH95114.1 - 0.014 15.2 3.7 0.044 13.6 0.8 2.9 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.6 KRH95114.1 - 0.042 14.2 6.6 0.052 13.9 1.5 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 KRH95114.1 - 0.044 13.2 11.4 0.86 9.1 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KRH95114.1 - 0.076 13.0 0.7 0.076 13.0 0.7 2.0 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DZR PF12773.7 KRH95114.1 - 0.086 12.9 6.7 0.28 11.2 6.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon UPF0167 PF03691.14 KRH95114.1 - 0.093 12.5 4.5 2.3 8.0 1.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) CHB_HEX_C_1 PF13290.6 KRH95114.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain NOB1_Zn_bind PF08772.11 KRH95114.1 - 0.11 12.7 3.4 2.8 8.2 0.0 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TniB PF05621.11 KRH95114.1 - 0.16 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein zinc_ribbon_2 PF13240.6 KRH95114.1 - 0.18 11.6 11.1 0.41 10.4 0.3 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KRH95114.1 - 0.28 11.2 4.7 0.24 11.4 1.0 2.4 2 2 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KRH95114.1 - 0.6 9.7 8.2 1.1 8.8 1.7 3.3 2 2 1 3 3 3 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 KRH95114.1 - 3.3 7.7 12.8 7.9 6.5 0.4 3.6 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-IS66 PF13005.7 KRH95114.1 - 3.4 8.1 0.1 3.4 8.1 0.1 3.0 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 RNase_HII PF01351.18 KRH95116.1 - 8.1 6.2 9.6 3.2 7.5 0.5 2.7 2 0 0 2 2 2 0 Ribonuclease HII Ribosomal_L27e PF01777.18 KRH95117.1 - 2.5e-06 27.7 0.9 3.4e-06 27.3 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family Peptidase_C28 PF05408.11 KRH95119.1 - 0.033 13.9 0.1 0.78 9.4 0.0 2.0 1 1 1 2 2 2 0 Foot-and-mouth virus L-proteinase TFIIS_C PF01096.18 KRH95120.1 - 3.3e-16 58.8 7.9 6e-16 58.0 7.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 KRH95120.1 - 8.2e-15 55.3 0.0 1.2e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Histone PF00125.24 KRH95123.1 - 1.8e-38 131.8 2.3 2.1e-38 131.7 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KRH95123.1 - 0.00068 20.2 3.1 0.00078 20.1 3.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 KRH95123.1 - 0.0049 17.2 0.0 0.0082 16.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KRH95123.1 - 0.014 15.5 0.1 0.032 14.4 0.0 1.6 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold DUF1460 PF07313.12 KRH95123.1 - 0.048 13.0 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) TFIID-31kDa PF02291.15 KRH95123.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PolyA_pol PF01743.20 KRH95124.1 - 9.7e-26 90.7 0.2 1.1e-24 87.3 0.0 2.5 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KRH95124.1 - 0.0014 18.3 0.4 0.0044 16.8 0.4 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Wzy_C PF04932.15 KRH95125.1 - 0.0025 17.5 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 2 O-Antigen ligase CobU PF02283.16 KRH95125.1 - 0.19 11.3 1.5 0.31 10.6 0.1 2.2 3 0 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Amastin PF07344.11 KRH95125.1 - 2.4 8.0 8.9 0.11 12.3 0.4 2.4 3 0 0 3 3 3 0 Amastin surface glycoprotein DUF3278 PF11683.8 KRH95125.1 - 3.3 7.8 15.5 2.5 8.2 0.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3278) Pkinase PF00069.25 KRH95128.1 - 6.7e-67 225.6 0.0 7.5e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KRH95128.1 - 1.3e-32 113.2 0.0 1.5e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KRH95128.1 - 0.00064 19.1 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KRH95128.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KRH95128.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KRH95128.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KRH95128.1 - 0.052 13.5 0.0 0.6 10.0 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 KRH95129.1 - 2.3e-12 47.0 6.9 2.3e-12 47.0 6.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KRH95129.1 - 4e-10 39.2 4.6 8.4e-10 38.2 4.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KRH95129.1 - 2.3e-07 30.5 6.6 2.3e-07 30.5 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH95129.1 - 2.9e-07 30.3 5.2 2.9e-07 30.3 5.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KRH95129.1 - 7.2e-07 29.4 8.0 7.2e-07 29.4 8.0 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KRH95129.1 - 1.8e-06 27.7 6.6 1.8e-06 27.7 6.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KRH95129.1 - 8.3e-06 25.6 3.6 8.3e-06 25.6 3.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KRH95129.1 - 7.1e-05 22.8 1.5 7.1e-05 22.8 1.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KRH95129.1 - 0.00042 20.1 6.6 0.00099 18.9 6.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KRH95129.1 - 0.00054 20.0 2.1 0.00054 20.0 2.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KRH95129.1 - 0.0059 16.2 5.0 0.0059 16.2 5.0 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KRH95129.1 - 0.011 15.9 9.3 0.6 10.3 9.3 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 KRH95129.1 - 0.025 14.5 1.4 0.054 13.4 1.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3H2C3 PF17122.5 KRH95129.1 - 0.087 12.9 10.3 0.34 11.0 9.5 2.5 1 1 1 2 2 2 0 Zinc-finger zinc_ribbon_16 PF17034.5 KRH95129.1 - 0.31 11.3 5.0 0.11 12.7 2.1 1.7 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3HC4_5 PF17121.5 KRH95129.1 - 0.97 9.4 6.3 12 5.9 1.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KRH95129.1 - 2.6 7.9 10.7 0.15 11.8 5.6 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 KRH95129.1 - 6.7 6.5 11.9 1.9 8.2 6.7 2.6 2 1 1 3 3 3 0 P-11 zinc finger Hist_deacetyl PF00850.19 KRH95130.1 - 1.1e-79 268.1 0.2 2.1e-79 267.2 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain TPR_19 PF14559.6 KRH95131.1 - 3.5e-09 37.0 2.6 0.002 18.6 0.1 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KRH95131.1 - 4.4e-05 23.7 3.2 0.4 11.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KRH95131.1 - 0.00018 22.0 0.1 2.2 9.3 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KRH95131.1 - 0.00025 21.2 0.5 1.8 9.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KRH95131.1 - 0.0014 18.6 5.1 0.53 10.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KRH95131.1 - 0.0029 17.4 3.4 1.4 8.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KRH95131.1 - 0.0044 16.7 0.8 6.2 6.6 0.0 4.2 4 0 0 4 4 4 1 TPR repeat TPR_20 PF14561.6 KRH95131.1 - 0.0057 17.0 3.9 0.012 16.0 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KRH95131.1 - 0.013 15.3 2.3 0.75 9.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 KRH95131.1 - 0.16 12.7 0.3 1.3 9.9 0.1 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat TPR_7 PF13176.6 KRH95131.1 - 0.17 12.0 1.9 13 6.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KRH95131.1 - 1.5 9.2 12.8 6.8 7.2 0.2 5.7 6 1 0 6 6 5 0 Tetratricopeptide repeat Ras PF00071.22 KRH95132.1 - 3.6e-54 182.7 2.3 4.3e-54 182.5 2.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH95132.1 - 3.1e-35 121.0 0.3 5.2e-35 120.3 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH95132.1 - 1.1e-16 60.8 0.9 1.4e-16 60.5 0.9 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KRH95132.1 - 1.2e-07 31.4 1.5 1.5e-07 31.1 1.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRH95132.1 - 3.4e-06 27.1 0.2 6.4e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KRH95132.1 - 4.6e-06 26.3 0.7 7.1e-06 25.7 0.7 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KRH95132.1 - 0.0036 16.8 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KRH95132.1 - 0.0059 16.5 2.1 0.036 14.0 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KRH95132.1 - 0.007 15.8 0.4 0.013 14.9 0.3 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KRH95132.1 - 0.0097 16.2 0.1 0.071 13.4 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KRH95132.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KRH95132.1 - 0.012 16.0 0.1 0.026 15.0 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KRH95132.1 - 0.026 14.5 0.1 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 KRH95132.1 - 0.11 12.3 1.0 0.19 11.5 1.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Met_10 PF02475.16 KRH95133.1 - 8.1e-37 126.9 0.4 1.5e-36 126.0 0.1 1.6 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 KRH95133.1 - 2.5e-09 36.9 0.0 5.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KRH95133.1 - 9.2e-05 23.1 0.0 0.00025 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 KRH95133.1 - 0.00039 20.2 0.9 0.0016 18.2 0.2 2.1 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.15 KRH95133.1 - 0.00083 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 KRH95133.1 - 0.0012 18.3 0.1 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltrans_SAM PF10672.9 KRH95133.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_15 PF09445.10 KRH95133.1 - 0.0022 17.6 0.4 0.0056 16.3 0.4 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KRH95133.1 - 0.0039 17.0 0.2 0.0095 15.7 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 KRH95133.1 - 0.015 14.5 0.6 0.033 13.4 0.1 1.8 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase UQ_con PF00179.26 KRH95134.1 - 1.5e-43 147.8 0.0 1.7e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KRH95134.1 - 0.024 14.9 0.2 0.028 14.7 0.2 1.4 1 1 0 1 1 1 0 RWD domain DUF5040 PF16443.5 KRH95134.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Ribosomal_S17 PF00366.20 KRH95135.1 - 8e-20 70.7 3.2 8e-20 70.7 3.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KRH95135.1 - 2.8e-16 59.6 1.8 5e-16 58.8 0.2 2.1 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ras PF00071.22 KRH95137.1 - 1.5e-56 190.4 0.6 1.8e-56 190.2 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH95137.1 - 1.4e-33 115.6 0.4 1.9e-33 115.2 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH95137.1 - 9.6e-16 57.7 0.2 1.1e-15 57.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KRH95137.1 - 3.8e-06 27.0 0.3 6.6e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KRH95137.1 - 4.7e-06 26.1 0.4 2.1e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KRH95137.1 - 4.8e-06 26.2 0.7 0.00041 20.0 0.7 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KRH95137.1 - 3.1e-05 24.0 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KRH95137.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KRH95137.1 - 0.0051 16.2 0.1 0.0078 15.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 KRH95137.1 - 0.01 15.7 0.6 0.012 15.5 0.6 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Septin PF00735.18 KRH95137.1 - 0.015 14.6 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 KRH95137.1 - 0.019 14.1 0.9 1.3 8.1 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 KRH95137.1 - 0.022 15.0 0.1 0.05 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KRH95137.1 - 0.026 14.1 0.1 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 KRH95137.1 - 0.033 13.9 0.2 0.067 12.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KRH95137.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KRH95137.1 - 0.048 13.9 0.1 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KRH95137.1 - 0.05 13.7 0.3 0.18 11.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KRH95137.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DAP3 PF10236.9 KRH95137.1 - 0.053 12.7 0.0 0.47 9.6 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KRH95137.1 - 0.057 13.9 0.4 0.072 13.6 0.4 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 KRH95137.1 - 0.061 13.1 0.2 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 KRH95137.1 - 0.062 12.4 0.2 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KRH95137.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KRH95137.1 - 0.08 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KRH95137.1 - 0.087 12.9 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KRH95137.1 - 0.091 12.8 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) VirE PF05272.11 KRH95137.1 - 0.096 12.4 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Virulence-associated protein E NACHT PF05729.12 KRH95137.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 2 0 0 2 2 1 0 NACHT domain AAA_23 PF13476.6 KRH95137.1 - 0.21 12.1 3.3 0.27 11.7 3.3 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.25 KRH95138.1 - 5.3e-12 45.8 14.6 5.3e-12 45.8 14.6 1.5 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KRH95138.1 - 9.1e-07 28.8 0.3 9.1e-07 28.8 0.3 1.8 2 0 0 2 2 2 1 SNARE domain VitD-bind_III PF09164.10 KRH95138.1 - 0.0099 15.9 0.1 0.032 14.2 0.1 1.9 1 0 0 1 1 1 1 Vitamin D binding protein, domain III YqzH PF14164.6 KRH95138.1 - 0.11 12.6 2.9 5.3 7.2 0.3 3.1 2 1 0 2 2 2 0 YqzH-like protein DUF948 PF06103.11 KRH95138.1 - 3 8.1 5.8 3 8.2 2.1 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF745 PF05335.13 KRH95138.1 - 4.8 6.9 7.1 1.7 8.3 2.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) MeMO_Hyd_G PF02964.16 KRH95139.1 - 0.0059 16.6 0.2 0.0059 16.6 0.2 2.3 2 1 0 2 2 2 1 Methane monooxygenase, hydrolase gamma chain PUF PF00806.19 KRH95139.1 - 0.011 15.4 0.2 0.6 9.9 0.0 3.6 4 0 0 4 4 4 0 Pumilio-family RNA binding repeat DUF2789 PF10982.8 KRH95139.1 - 0.024 14.8 0.1 0.062 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) RPAP1_N PF08621.10 KRH95139.1 - 0.034 13.9 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 RPAP1-like, N-terminal EF-hand_7 PF13499.6 KRH95140.1 - 8.6e-14 51.8 7.5 1.2e-07 32.1 3.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KRH95140.1 - 1.9e-11 42.7 1.7 0.029 13.9 0.2 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KRH95140.1 - 4e-10 38.8 4.9 0.012 15.4 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KRH95140.1 - 1.6e-06 27.9 5.2 0.042 13.7 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KRH95140.1 - 0.11 12.8 0.3 3 8.2 0.0 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 KRH95140.1 - 0.17 11.5 0.7 0.54 9.9 0.0 2.3 3 0 0 3 3 3 0 EF hand Sigma70_r1_1 PF03979.14 KRH95140.1 - 0.59 10.2 2.3 4 7.6 0.6 2.7 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 YchF-GTPase_C PF06071.13 KRH95141.1 - 1.5e-37 127.7 0.4 4.3e-37 126.2 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KRH95141.1 - 3.3e-22 78.7 0.0 9.6e-22 77.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KRH95141.1 - 2.5e-08 33.6 0.0 6.9e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KRH95141.1 - 0.02 14.9 0.7 9.8 6.2 0.0 3.1 3 1 1 4 4 4 0 Dynamin family TGS PF02824.21 KRH95141.1 - 0.029 14.4 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 TGS domain DUF4803 PF16061.5 KRH95141.1 - 0.042 13.3 0.5 0.071 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) MeaB PF03308.16 KRH95141.1 - 0.042 12.8 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KRH95141.1 - 0.098 13.2 0.0 0.62 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter zf-C2H2 PF00096.26 KRH95142.1 - 5.3e-12 45.5 31.3 0.0009 19.6 1.1 5.4 4 1 1 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KRH95142.1 - 1.8e-08 34.5 37.3 0.05 14.5 0.5 5.6 6 0 0 6 6 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KRH95142.1 - 6.2e-06 26.3 32.1 0.047 14.0 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KRH95142.1 - 0.00018 21.4 25.9 0.00068 19.6 0.9 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf_UBZ PF18439.1 KRH95142.1 - 0.0014 18.2 10.1 0.62 9.7 0.0 4.4 3 1 1 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_8 PF15909.5 KRH95142.1 - 0.0019 18.4 6.3 0.0019 18.4 6.3 3.0 2 2 1 3 3 3 1 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 KRH95142.1 - 0.0057 17.3 4.5 0.0057 17.3 4.5 2.9 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 KRH95142.1 - 0.046 14.1 0.2 0.046 14.1 0.2 5.7 5 1 1 6 6 6 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KRH95142.1 - 0.048 14.1 0.3 0.048 14.1 0.3 5.4 6 0 0 6 6 5 0 Zinc-finger double domain DUF5077 PF16871.5 KRH95142.1 - 0.053 13.4 0.2 10 6.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5077) C1_4 PF07975.12 KRH95142.1 - 0.2 11.9 17.2 3.5 7.9 1.6 3.7 2 1 1 3 3 3 0 TFIIH C1-like domain zf-LYAR PF08790.11 KRH95142.1 - 0.23 11.4 0.3 0.23 11.4 0.3 3.8 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger Zf_RING PF16744.5 KRH95142.1 - 1.1 9.4 0.0 1.1 9.4 0.0 4.4 2 1 3 5 5 3 0 KIAA1045 RING finger Spt46 PF17734.1 KRH95142.1 - 1.1 9.0 15.1 0.052 13.3 4.5 2.8 2 1 2 4 4 4 0 Spermatogenesis-associated protein 46 zf-3CxxC PF13695.6 KRH95142.1 - 1.2 9.6 16.6 3.9 8.0 7.9 3.1 2 1 0 3 3 3 0 Zinc-binding domain DUF4379 PF14311.6 KRH95142.1 - 1.7 9.1 11.2 16 5.9 0.1 3.6 2 1 2 4 4 4 0 Probable Zinc-ribbon domain XPA_N PF01286.18 KRH95142.1 - 1.9 8.6 11.6 23 5.1 0.2 4.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-AN1 PF01428.16 KRH95142.1 - 1.9 8.7 21.7 15 5.9 0.5 5.1 5 0 0 5 5 5 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 KRH95142.1 - 3.5 7.6 24.3 0.25 11.3 1.7 4.8 4 1 0 4 4 4 0 zinc-finger of a C2HC-type LSM PF01423.22 KRH95143.1 - 4.3e-12 45.6 1.2 6.6e-12 45.0 1.2 1.3 1 0 0 1 1 1 1 LSM domain Rad21_Rec8_N PF04825.13 KRH95143.1 - 0.07 13.3 0.9 0.099 12.8 0.9 1.2 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein DUF883 PF05957.13 KRH95144.1 - 0.15 12.7 0.0 1.2 9.8 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF45 PF01863.17 KRH95144.1 - 5.7 6.9 8.8 12 5.9 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF45 ZT_dimer PF16916.5 KRH95145.1 - 0.045 13.9 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF2112 PF09885.9 KRH95146.1 - 0.078 13.0 0.1 0.096 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) TFB6 PF17110.5 KRH95146.1 - 0.33 10.7 1.4 0.46 10.2 1.4 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4834 PF16118.5 KRH95147.1 - 0.024 15.6 1.1 0.024 15.6 1.1 4.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF4632 PF15451.6 KRH95147.1 - 2.3 8.4 0.0 2.3 8.4 0.0 6.1 4 1 3 8 8 8 0 Domain of unknown function (DUF4632) Forkhead PF00250.18 KRH95149.1 - 1.7e-31 108.3 1.3 3.1e-31 107.5 1.3 1.4 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 KRH95149.1 - 0.033 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family CDC73_C PF05179.14 KRH95151.1 - 0.00089 19.0 1.2 0.0015 18.2 1.2 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF5065 PF16723.5 KRH95151.1 - 0.017 15.2 1.0 0.017 15.2 1.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) DsrC PF04358.13 KRH95151.1 - 0.061 13.8 0.6 1.8 9.1 0.0 2.4 2 1 0 2 2 2 0 DsrC like protein Nop10p PF04135.12 KRH95153.1 - 2.5e-07 30.6 0.6 1.7e-06 28.0 0.6 1.9 1 1 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Homeodomain PF00046.29 KRH95154.1 - 8.2e-15 54.4 0.7 1.5e-14 53.6 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KRH95154.1 - 0.043 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.6 KRH95154.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Homeodomain PF00046.29 KRH95157.1 - 3.3e-13 49.3 0.8 5.9e-13 48.4 0.8 1.4 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 KRH95157.1 - 0.0035 17.2 0.1 0.0073 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 KRH95157.1 - 0.0043 16.9 0.2 0.015 15.2 0.1 1.9 1 1 1 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 KRH95157.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.6 KRH95157.1 - 0.093 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 KRH95157.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_17 PF12728.7 KRH95157.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Actin PF00022.19 KRH95160.1 - 1.2e-139 465.5 0.0 1.5e-138 461.8 0.0 1.9 1 1 0 1 1 1 1 Actin Peptidase_M18 PF02127.15 KRH95161.1 - 3.6e-57 194.1 0.1 2.1e-56 191.6 0.1 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KRH95161.1 - 7.8e-06 25.1 0.0 1.9e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MtaB PF12176.8 KRH95162.1 - 0.086 11.6 2.4 0.1 11.3 2.4 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit ETRAMP PF09716.10 KRH95162.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MCM PF00493.23 KRH95163.1 - 2.1e-81 272.3 0.2 3.8e-81 271.5 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KRH95163.1 - 4.6e-21 75.0 1.4 8.8e-21 74.1 1.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KRH95163.1 - 4.7e-16 59.0 0.3 1.2e-15 57.6 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KRH95163.1 - 8.2e-10 38.4 0.0 1.5e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KRH95163.1 - 1.2e-07 31.8 0.0 5.6e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM6_C PF18263.1 KRH95163.1 - 3.5e-05 24.0 2.3 3.5e-05 24.0 2.3 3.2 3 0 0 3 3 3 1 MCM6 C-terminal winged-helix domain AAA_3 PF07726.11 KRH95163.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EspA PF03433.13 KRH95163.1 - 0.026 14.4 1.0 0.087 12.7 0.1 2.4 2 0 0 2 2 2 0 EspA-like secreted protein AAA PF00004.29 KRH95163.1 - 0.044 14.2 0.1 0.17 12.3 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KRH95163.1 - 0.058 13.1 0.0 1.8 8.2 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain EABR PF12180.8 KRH95164.1 - 0.2 11.3 2.4 6.9 6.4 0.1 3.4 2 1 1 3 3 3 0 TSG101 and ALIX binding domain of CEP55 GET2 PF08690.10 KRH95165.1 - 0.35 10.5 7.2 0.043 13.5 2.0 1.9 1 1 1 2 2 2 0 GET complex subunit GET2 PS_Dcarbxylase PF02666.15 KRH95166.1 - 1.6e-38 132.3 0.0 2.9e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Herpes_LMP1 PF05297.11 KRH95166.1 - 0.052 12.7 2.6 0.077 12.2 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF883 PF05957.13 KRH95167.1 - 0.026 15.1 0.2 0.026 15.1 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 KRH95167.1 - 0.092 12.1 8.2 0.1 11.9 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PXA PF02194.15 KRH95167.1 - 0.27 11.2 2.8 0.33 10.9 2.8 1.2 1 0 0 1 1 1 0 PXA domain Presenilin PF01080.17 KRH95167.1 - 0.71 8.6 4.2 0.73 8.5 4.2 1.1 1 0 0 1 1 1 0 Presenilin PDCD7 PF16021.5 KRH95167.1 - 0.95 8.5 20.7 1.6 7.7 20.7 1.5 1 1 0 1 1 1 0 Programmed cell death protein 7 GvpL_GvpF PF06386.11 KRH95167.1 - 1 9.2 9.4 1.5 8.7 9.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF LMBR1 PF04791.16 KRH95167.1 - 1.4 7.7 7.2 1.7 7.4 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Interferon PF00143.19 KRH95167.1 - 1.6 8.9 15.7 2.3 8.4 15.6 1.4 1 1 0 1 1 1 0 Interferon alpha/beta domain YtxH PF12732.7 KRH95167.1 - 1.9 9.0 16.3 0.29 11.7 3.4 2.3 1 1 1 2 2 2 0 YtxH-like protein AAA_23 PF13476.6 KRH95167.1 - 2.2 8.7 18.3 2.9 8.3 18.3 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KRH95167.1 - 2.7 7.5 11.6 3 7.3 11.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit O-antigen_lig PF13425.6 KRH95167.1 - 3.2 6.4 6.6 4 6.1 6.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein WSD PF15613.6 KRH95167.1 - 3.4 8.2 9.9 5.1 7.6 9.7 1.4 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif GBP_C PF02841.14 KRH95167.1 - 4.2 6.7 25.3 12 5.2 25.2 1.7 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF2526 PF10735.9 KRH95167.1 - 5.2 7.3 8.6 1.5 9.1 5.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) DnaJ PF00226.31 KRH95171.1 - 0.00017 21.7 1.4 0.00017 21.7 1.4 2.4 2 0 0 2 2 2 1 DnaJ domain Rcd1 PF04078.13 KRH95172.1 - 4.7e-57 193.2 9.2 7.1e-57 192.7 9.2 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sdh5 PF03937.16 KRH95172.1 - 0.047 13.7 0.2 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase AAA PF00004.29 KRH95173.1 - 1e-18 68.1 0.3 9.1e-12 45.5 0.3 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KRH95173.1 - 0.0002 21.1 0.1 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KRH95173.1 - 0.00051 20.5 0.0 0.0026 18.2 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KRH95173.1 - 0.00057 20.2 0.0 0.029 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KRH95173.1 - 0.0007 19.5 17.5 0.0007 19.5 17.5 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KRH95173.1 - 0.0025 17.6 0.1 0.0072 16.0 0.1 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 KRH95173.1 - 0.0028 17.8 1.4 0.036 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KRH95173.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KRH95173.1 - 0.0056 16.6 0.3 0.28 11.1 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 KRH95173.1 - 0.012 15.4 0.0 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KRH95173.1 - 0.015 15.3 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 KRH95173.1 - 0.019 15.3 0.0 0.051 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRH95173.1 - 0.022 14.5 0.0 0.072 12.9 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KRH95173.1 - 0.022 13.8 0.1 0.039 13.0 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KRH95173.1 - 0.036 14.2 0.3 2.1 8.5 0.2 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KRH95173.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KRH95173.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KRH95173.1 - 0.11 13.0 13.1 0.087 13.4 4.2 3.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KRH95173.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KRH95173.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KRH95173.1 - 5.9 7.3 7.3 3.2 8.2 2.1 3.2 2 1 0 2 2 2 0 AAA domain NMT PF01233.19 KRH95174.1 - 4.7e-10 39.5 0.0 1.6e-06 28.1 0.0 2.9 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 KRH95174.1 - 0.00022 21.4 0.0 0.011 16.0 0.0 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KRH95174.1 - 0.015 15.7 0.4 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Presenilin PF01080.17 KRH95176.1 - 2.8 6.6 6.5 3.3 6.4 6.5 1.2 1 0 0 1 1 1 0 Presenilin PIP49_N PF14875.6 KRH95177.1 - 0.63 9.9 3.0 2.6 7.9 0.1 2.7 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 DUF2852 PF11014.8 KRH95178.1 - 2.2 8.5 10.8 18 5.5 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Nop25 PF09805.9 KRH95179.1 - 0.053 14.0 23.0 0.058 13.9 23.0 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) XhlA PF10779.9 KRH95179.1 - 1.2 9.4 9.0 1.8 8.8 9.0 1.5 1 1 0 1 1 1 0 Haemolysin XhlA DUF3464 PF11947.8 KRH95179.1 - 1.9 8.2 10.4 2.1 8.1 10.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Med19 PF10278.9 KRH95179.1 - 4.4 7.2 21.3 5 7.0 21.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 KRH95179.1 - 8.7 5.0 6.6 8.4 5.0 6.6 1.0 1 0 0 1 1 1 0 Presenilin Folate_carrier PF01770.18 KRH95179.1 - 8.8 4.9 5.6 8 5.1 5.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF5300 PF17224.3 KRH95180.1 - 0.037 14.3 0.5 0.056 13.7 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) G6PD_C PF02781.16 KRH95180.1 - 0.048 12.9 0.2 0.062 12.5 0.2 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain GET2 PF08690.10 KRH95180.1 - 0.16 11.7 2.5 0.21 11.2 1.0 1.7 1 1 1 2 2 2 0 GET complex subunit GET2 BAR_2 PF10455.9 KRH95182.1 - 7.6e-08 31.8 13.6 1.1e-07 31.4 13.4 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Syntaxin PF00804.25 KRH95182.1 - 0.00012 21.9 10.8 0.0035 17.1 6.9 2.2 2 0 0 2 2 2 2 Syntaxin BAR PF03114.18 KRH95182.1 - 0.00031 20.5 11.8 0.00078 19.2 11.8 1.7 1 1 0 1 1 1 1 BAR domain DHR10 PF18595.1 KRH95182.1 - 0.0017 18.4 3.8 0.0017 18.4 3.8 2.0 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain PHM7_cyt PF14703.6 KRH95182.1 - 0.0035 17.6 7.5 0.004 17.4 0.1 2.4 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 KRH95182.1 - 0.053 13.5 9.5 0.09 12.8 6.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4239 PF14023.6 KRH95182.1 - 0.081 12.6 0.6 0.16 11.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) OGG_N PF07934.12 KRH95182.1 - 0.11 12.5 2.7 0.48 10.5 2.6 2.2 1 1 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain CRS1_YhbY PF01985.21 KRH95182.1 - 0.15 12.3 1.3 0.35 11.1 0.7 1.8 1 1 0 2 2 2 0 CRS1 / YhbY (CRM) domain FlgN PF05130.12 KRH95182.1 - 0.23 11.9 5.1 0.22 12.0 2.3 2.2 2 1 1 3 3 3 0 FlgN protein DUF1664 PF07889.12 KRH95182.1 - 0.25 11.4 11.4 0.28 11.2 3.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4298 PF14131.6 KRH95182.1 - 0.35 10.9 10.2 0.14 12.1 2.5 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) APG6_N PF17675.1 KRH95182.1 - 0.52 10.9 7.6 0.26 11.8 4.9 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Hrs_helical PF12210.8 KRH95182.1 - 0.57 10.8 12.0 0.98 10.0 0.3 3.5 2 1 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Prefoldin_2 PF01920.20 KRH95182.1 - 0.68 9.9 13.5 2.3 8.2 2.5 3.7 3 1 0 3 3 3 0 Prefoldin subunit bZIP_1 PF00170.21 KRH95182.1 - 1.2 9.3 8.3 0.41 10.8 0.7 2.9 2 1 0 2 2 2 0 bZIP transcription factor Occludin_ELL PF07303.13 KRH95182.1 - 1.2 9.9 11.0 2.3 9.0 2.7 2.9 1 1 2 3 3 3 0 Occludin homology domain CREPT PF16566.5 KRH95182.1 - 2.8 8.1 9.0 0.36 11.0 3.3 2.3 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour STAT_alpha PF01017.20 KRH95182.1 - 2.9 7.8 9.6 2.1 8.2 4.8 2.5 1 1 1 2 2 2 0 STAT protein, all-alpha domain Choline_sulf_C PF12411.8 KRH95185.1 - 0.2 11.5 1.3 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Choline sulfatase enzyme C terminal CAF1 PF04857.20 KRH95187.1 - 6.7e-15 55.1 3.5 8.3e-08 31.8 0.2 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease PAT1 PF09770.9 KRH95188.1 - 4.4e-06 25.3 0.2 4.4e-06 25.3 0.2 2.0 2 1 0 2 2 2 1 Topoisomerase II-associated protein PAT1 ORF6N PF10543.9 KRH95188.1 - 0.13 12.5 3.3 13 6.1 0.1 3.2 3 0 0 3 3 3 0 ORF6N domain GIT_SHD PF08518.11 KRH95189.1 - 4.8e-07 29.3 5.3 0.0019 17.8 0.1 3.3 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Sec1 PF00995.23 KRH95189.1 - 0.00044 19.6 14.4 0.00065 19.1 14.4 1.2 1 0 0 1 1 1 1 Sec1 family HARP PF07443.13 KRH95189.1 - 0.12 12.0 1.8 0.23 11.1 0.2 2.4 3 0 0 3 3 3 0 HepA-related protein (HARP) HECW1_helix PF18436.1 KRH95189.1 - 0.2 11.8 1.9 4.2 7.6 0.1 3.0 3 0 0 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 tRNA-synt_1d PF00750.19 KRH95190.1 - 1.3e-77 261.2 10.6 2.4e-76 257.0 10.6 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KRH95190.1 - 2.7e-19 69.5 0.0 9.4e-19 67.7 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KRH95190.1 - 0.26 11.9 5.5 0.95 10.1 2.1 2.9 2 1 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain DUF2274 PF10038.9 KRH95190.1 - 0.78 10.2 2.7 14 6.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) Glycos_transf_2 PF00535.26 KRH95191.1 - 8.1e-26 90.8 0.0 1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KRH95191.1 - 1.9e-05 24.7 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KRH95191.1 - 0.055 12.9 0.2 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KRH95191.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KRH95191.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 TPR_11 PF13414.6 KRH95192.1 - 8.3e-08 31.8 1.6 1.2e-06 28.1 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 KRH95192.1 - 4.7e-06 27.2 0.0 7.1e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KRH95192.1 - 5.9e-05 22.7 8.8 0.081 12.8 0.4 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KRH95192.1 - 0.00028 20.8 13.3 0.0075 16.3 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KRH95192.1 - 0.00058 19.9 21.2 0.036 14.3 0.2 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 KRH95192.1 - 0.0066 16.4 4.0 11 6.3 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Ribosomal_L4 PF00573.22 KRH95193.1 - 3.2e-34 118.3 0.1 4.5e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KRH95193.1 - 0.034 14.2 0.3 0.39 10.8 0.0 2.8 3 1 0 3 3 3 0 60S ribosomal protein L4 C-terminal domain SRP19 PF01922.17 KRH95194.1 - 1.5e-18 67.5 1.1 1.5e-18 67.5 1.1 2.0 1 1 1 2 2 2 1 SRP19 protein TIM PF00121.18 KRH95195.1 - 9.7e-69 231.4 0.4 1.2e-68 231.1 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.24 KRH95195.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Lectin_leg-like PF03388.13 KRH95196.1 - 9.6e-10 38.2 0.1 6.5e-09 35.5 0.1 2.1 1 1 0 1 1 1 1 Legume-like lectin family DUF4854 PF16146.5 KRH95197.1 - 0.0087 16.4 1.8 0.058 13.7 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4854) DUF4116 PF13475.6 KRH95197.1 - 4.1 7.2 7.0 24 4.7 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) DUF5381 PF17353.2 KRH95198.1 - 0.016 14.9 12.9 0.48 10.2 3.7 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5381) CTX_RstB PF07459.11 KRH95198.1 - 0.02 15.1 0.2 6.1 7.1 0.0 2.4 1 1 1 2 2 2 0 CTX phage RstB protein RNA_pol_Rpb1_2 PF00623.20 KRH95198.1 - 0.021 15.1 0.3 3.3 7.9 0.0 2.2 1 1 2 3 3 3 0 RNA polymerase Rpb1, domain 2 DUF1310 PF07006.11 KRH95198.1 - 0.082 12.9 6.7 13 5.8 0.2 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1310) Endonuc_subdom PF09062.10 KRH95198.1 - 3 8.7 11.0 5.4 7.9 1.9 2.4 1 1 2 3 3 3 0 PI-PfuI Endonuclease subdomain MutS_V PF00488.21 KRH95200.1 - 9.2e-50 169.3 0.1 2.5e-49 167.9 0.1 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KRH95200.1 - 1e-17 65.0 1.4 2.8e-17 63.5 1.4 1.7 1 0 0 1 1 1 1 MutS domain III AAA_27 PF13514.6 KRH95200.1 - 0.079 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.18 KRH95200.1 - 0.1 12.9 6.0 1.3 9.4 5.4 2.9 1 1 1 2 2 2 0 MutS family domain IV AAA_29 PF13555.6 KRH95200.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KRH95200.1 - 5 7.6 5.6 1.7 9.1 0.2 2.7 3 0 0 3 3 3 0 ABC transporter DUF3848 PF12959.7 KRH95201.1 - 0.027 14.5 1.0 0.051 13.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) BHD_1 PF10403.9 KRH95202.1 - 1e-11 44.5 0.3 2.3e-11 43.3 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 KRH95202.1 - 5.8e-10 39.4 1.8 2.3e-09 37.5 0.2 2.7 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 3 SPC12 PF06645.13 KRH95203.1 - 1e-20 73.6 1.2 1.2e-20 73.4 1.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2207 PF09972.9 KRH95203.1 - 0.21 10.3 1.4 0.23 10.2 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2666 PF10869.8 KRH95204.1 - 0.89 9.8 8.8 0.16 12.2 2.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) MAT1 PF06391.13 KRH95205.1 - 1.9e-16 60.5 6.8 2.5e-16 60.1 6.8 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KRH95205.1 - 5.3e-16 58.3 6.9 1e-15 57.3 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH95205.1 - 1.2e-05 25.1 8.2 3.1e-05 23.7 8.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KRH95205.1 - 9.9e-05 22.2 7.0 0.0002 21.2 7.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KRH95205.1 - 0.00015 21.5 5.0 0.0014 18.4 2.1 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KRH95205.1 - 0.00073 19.3 8.0 0.0027 17.5 8.1 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KRH95205.1 - 0.0009 19.5 6.7 0.0019 18.5 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain DZR PF12773.7 KRH95205.1 - 0.0013 18.8 4.4 0.0021 18.0 4.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.6 KRH95205.1 - 0.011 15.5 9.8 0.057 13.3 9.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 KRH95205.1 - 0.039 13.5 5.6 0.56 9.8 1.2 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_6 PF14835.6 KRH95205.1 - 0.095 12.6 8.4 1 9.3 8.4 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein HscB_4_cys PF18256.1 KRH95205.1 - 0.22 11.4 0.3 0.22 11.4 0.3 2.2 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-ribbon_3 PF13248.6 KRH95205.1 - 0.23 10.9 8.0 4.3 6.9 0.4 2.7 2 1 1 3 3 3 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 KRH95205.1 - 0.41 10.7 8.8 0.85 9.7 8.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF3797 PF12677.7 KRH95205.1 - 0.52 10.2 4.8 2.5 8.0 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-UDP PF14569.6 KRH95205.1 - 0.56 10.4 5.9 5.7 7.1 5.9 2.2 1 1 0 1 1 1 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 KRH95205.1 - 0.76 9.9 5.5 12 6.1 2.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_S21e PF01249.18 KRH95206.1 - 1.6e-09 37.8 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e DUF915 PF06028.11 KRH95206.1 - 0.14 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Na_Ca_ex PF01699.24 KRH95211.1 - 2.2e-18 66.6 43.0 5.2e-12 46.0 7.9 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Sad1_UNC PF07738.13 KRH95212.1 - 3.3e-08 33.6 0.5 7.8e-08 32.4 0.5 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ribosomal_L18A PF01775.17 KRH95213.1 - 3e-24 85.4 2.4 5e-24 84.7 2.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A AAA_5 PF07728.14 KRH95214.1 - 5.9e-78 259.6 0.0 8.4e-23 80.9 0.0 6.8 6 1 0 6 6 6 5 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KRH95214.1 - 2.2e-32 111.7 0.0 1.1e-07 31.8 0.0 6.0 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KRH95214.1 - 1.9e-24 86.6 0.8 1.8e-05 25.2 0.0 5.2 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KRH95214.1 - 1.6e-21 76.6 2.2 3e-05 23.6 0.1 5.8 5 1 0 5 5 5 4 P-loop containing dynein motor region AAA_16 PF13191.6 KRH95214.1 - 2.5e-19 70.3 0.0 0.0004 20.8 0.0 4.9 4 0 0 4 4 4 4 AAA ATPase domain AAA_6 PF12774.7 KRH95214.1 - 3.2e-18 65.8 0.2 0.0041 16.1 0.0 7.5 6 1 0 6 6 6 4 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KRH95214.1 - 8.8e-17 61.7 9.4 6.7e-05 23.2 0.1 6.4 5 1 0 5 5 5 4 AAA domain AAA_14 PF13173.6 KRH95214.1 - 2.2e-11 43.9 21.6 0.00093 19.2 0.0 7.6 7 1 1 8 8 6 4 AAA domain TsaE PF02367.17 KRH95214.1 - 5.7e-11 42.5 0.1 0.046 13.7 0.0 4.9 4 0 0 4 4 4 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 KRH95214.1 - 2.8e-10 40.2 0.0 0.14 11.8 0.0 4.9 4 0 0 4 4 4 3 Sigma-54 interaction domain RNA_helicase PF00910.22 KRH95214.1 - 5.3e-09 36.4 0.0 1.2 9.5 0.0 5.7 4 0 0 4 4 4 3 RNA helicase AAA_19 PF13245.6 KRH95214.1 - 3.9e-08 33.8 0.9 1.3 9.3 0.0 5.6 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.6 KRH95214.1 - 4.2e-08 33.5 0.0 0.28 11.3 0.0 4.7 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 KRH95214.1 - 5.5e-08 32.2 0.0 0.17 11.0 0.0 4.6 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_18 PF13238.6 KRH95214.1 - 7.6e-08 33.0 15.0 0.058 13.9 0.0 7.3 6 0 0 6 6 5 2 AAA domain RuvB_N PF05496.12 KRH95214.1 - 1.2e-07 31.6 4.5 0.43 10.3 0.1 6.6 5 2 1 6 6 5 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KRH95214.1 - 1.7e-07 31.3 0.3 0.11 12.4 0.0 4.9 4 1 0 4 4 4 1 NACHT domain RsgA_GTPase PF03193.16 KRH95214.1 - 5.3e-07 29.7 0.1 0.92 9.4 0.0 5.1 4 0 0 4 4 4 1 RsgA GTPase DUF815 PF05673.13 KRH95214.1 - 6.2e-07 28.8 0.0 3.5 6.7 0.0 4.6 4 0 0 4 4 4 2 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KRH95214.1 - 1.9e-06 27.9 2.0 0.2 11.6 0.1 4.5 4 0 0 4 4 3 2 NTPase AAA_24 PF13479.6 KRH95214.1 - 3.4e-06 26.9 0.0 1.1 9.0 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KRH95214.1 - 5.4e-06 26.3 0.0 3.2 7.4 0.0 4.7 5 1 0 5 5 4 1 AAA domain AAA_28 PF13521.6 KRH95214.1 - 7.2e-06 26.3 0.6 10 6.3 0.0 4.6 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 KRH95214.1 - 1.5e-05 24.7 0.1 0.89 9.1 0.1 3.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KRH95214.1 - 5.3e-05 23.0 0.3 0.2 11.4 0.1 4.3 4 1 0 4 4 4 1 IstB-like ATP binding protein TniB PF05621.11 KRH95214.1 - 8.1e-05 22.1 0.1 2.7 7.4 0.0 4.5 4 0 0 4 4 4 1 Bacterial TniB protein Mg_chelatase PF01078.21 KRH95214.1 - 0.00013 21.4 0.6 6.7 6.0 0.0 5.5 5 1 0 5 5 4 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KRH95214.1 - 0.00035 20.4 1.6 0.83 9.3 0.0 4.8 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KRH95214.1 - 0.00064 19.5 0.0 0.32 10.8 0.0 3.8 3 1 0 3 3 3 1 DEAD/DEAH box helicase PduV-EutP PF10662.9 KRH95214.1 - 0.0011 18.7 1.6 8.8 6.1 0.0 4.7 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 KRH95214.1 - 0.0014 18.8 0.6 6.6 6.9 0.0 4.6 5 0 0 5 5 4 0 Sigma-54 interaction domain Roc PF08477.13 KRH95214.1 - 0.0031 17.7 1.5 16 5.7 0.1 5.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 KRH95214.1 - 0.0068 16.1 0.2 2.6 7.7 0.0 3.8 3 0 0 3 3 3 1 Thymidylate kinase AAA_29 PF13555.6 KRH95214.1 - 0.0069 16.1 0.1 41 4.0 0.0 4.5 4 0 0 4 4 4 0 P-loop containing region of AAA domain Dynein_heavy PF03028.15 KRH95214.1 - 0.025 14.7 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 1 0 Dynein heavy chain region D6 P-loop domain FtsK_SpoIIIE PF01580.18 KRH95214.1 - 0.025 13.9 0.0 14 4.9 0.0 3.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family MCM PF00493.23 KRH95214.1 - 0.028 13.5 2.8 0.53 9.3 0.0 4.1 5 1 0 5 5 5 0 MCM P-loop domain MMR_HSR1 PF01926.23 KRH95214.1 - 0.086 12.9 1.0 33 4.6 0.0 4.3 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_11 PF13086.6 KRH95214.1 - 0.12 12.1 0.0 0.12 12.1 0.0 7.0 7 1 1 8 8 5 0 AAA domain Aldo_ket_red PF00248.21 KRH95215.1 - 3.7e-06 26.4 0.0 3.8e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BMFP PF04380.13 KRH95215.1 - 0.13 12.8 0.4 0.16 12.5 0.4 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity Aldo_ket_red PF00248.21 KRH95217.1 - 2.9e-43 148.1 0.1 2.2e-41 142.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_52 PF18576.1 KRH95217.1 - 0.051 13.8 0.1 0.24 11.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5092 PF17010.5 KRH95218.1 - 4.4e-50 169.8 18.0 2.2e-48 164.3 18.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) Ras PF00071.22 KRH95219.1 - 1.5e-52 177.5 0.1 1.7e-52 177.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KRH95219.1 - 5.2e-32 110.6 0.1 1.5e-31 109.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KRH95219.1 - 1.4e-13 50.6 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KRH95219.1 - 4e-07 29.6 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KRH95219.1 - 8.4e-06 25.9 0.0 1.5e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KRH95219.1 - 0.002 18.0 0.1 0.11 12.4 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KRH95219.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AP_endonuc_2 PF01261.24 KRH95221.1 - 5.3e-28 97.9 0.1 8.4e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1266 PF06889.11 KRH95224.1 - 0.017 15.1 0.7 0.78 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Prenyltrans PF00432.21 KRH95225.1 - 3e-26 90.8 1.3 8.8e-09 35.0 0.1 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KRH95225.1 - 0.0092 15.1 0.0 3.5 6.6 0.0 2.9 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain EMP24_GP25L PF01105.24 KRH95226.1 - 3.4e-09 36.9 0.4 4.2e-09 36.6 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD fn3_5 PF06280.12 KRH95226.1 - 0.037 14.7 0.2 0.054 14.2 0.2 1.3 1 0 0 1 1 1 0 Fn3-like domain DUF5643 PF18705.1 KRH95226.1 - 0.07 13.1 0.4 0.16 12.0 0.4 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5643) Transketolase_N PF00456.21 KRH95228.1 - 2.4e-72 243.7 0.1 3.9e-72 243.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KRH95228.1 - 8.3e-31 107.0 0.0 7e-29 100.8 0.0 2.6 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KRH95228.1 - 4e-13 49.3 0.0 8.3e-12 45.1 0.0 2.8 2 1 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 KRH95228.1 - 1.2e-06 27.7 0.0 2.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KRH95228.1 - 2e-05 24.5 0.2 7.9e-05 22.5 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KRH95228.1 - 0.018 14.2 3.6 0.061 12.5 0.1 2.7 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase ThiF PF00899.21 KRH95229.1 - 1e-31 110.1 0.3 1.2e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 KRH95229.1 - 0.0041 17.5 0.1 0.11 13.0 0.1 2.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KRH95229.1 - 0.029 14.4 0.4 0.41 10.7 0.0 2.6 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Transcrip_act PF04949.13 KRH95229.1 - 0.1 12.5 4.3 0.1 12.5 2.3 1.9 2 0 0 2 2 2 0 Transcriptional activator Cytidylate_kin PF02224.18 KRH95230.1 - 2.8e-50 171.0 0.1 3.3e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 KRH95230.1 - 6.9e-07 29.6 1.5 1.6e-06 28.4 1.5 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 KRH95230.1 - 6.7e-06 26.6 0.3 0.00045 20.6 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KRH95230.1 - 1.8e-05 25.3 0.3 0.00024 21.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 KRH95230.1 - 0.0053 16.9 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.19 KRH95230.1 - 0.012 15.5 0.1 0.28 11.0 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_33 PF13671.6 KRH95230.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain ENTH PF01417.20 KRH95230.1 - 0.035 14.2 0.9 0.14 12.2 0.9 2.0 1 1 1 2 2 2 0 ENTH domain KTI12 PF08433.10 KRH95230.1 - 0.059 12.8 0.2 0.16 11.4 0.2 1.9 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 KRH95230.1 - 0.071 13.0 0.0 0.82 9.6 0.0 2.3 2 1 1 3 3 3 0 NACHT domain PRK PF00485.18 KRH95230.1 - 0.095 12.4 0.3 0.21 11.3 0.1 1.8 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ThiF PF00899.21 KRH95231.1 - 3.1e-56 190.5 0.3 4.3e-56 190.0 0.3 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KRH95231.1 - 0.00039 20.9 0.2 0.0037 17.8 0.0 2.7 3 1 0 3 3 3 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 KRH95231.1 - 0.0005 20.3 0.2 0.061 13.6 0.2 3.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KRH95231.1 - 0.031 14.3 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SMC_N PF02463.19 KRH95232.1 - 1.5e-14 54.0 32.7 5.3e-11 42.4 22.9 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KRH95232.1 - 2.3e-13 50.5 0.2 9.7e-13 48.5 0.2 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 KRH95232.1 - 0.0034 17.1 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KRH95232.1 - 0.014 16.0 22.2 0.35 11.4 0.2 4.4 3 1 0 3 3 3 0 ABC transporter SbcCD_C PF13558.6 KRH95232.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CENP-H PF05837.12 KRH95233.1 - 0.0025 18.2 0.5 0.003 18.0 0.5 1.0 1 0 0 1 1 1 1 Centromere protein H (CENP-H) Pcc1 PF09341.10 KRH95233.1 - 0.097 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Pcc1 zf-RING_2 PF13639.6 KRH95235.1 - 4.5e-12 46.1 10.1 8.4e-12 45.2 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KRH95235.1 - 1.4e-09 38.1 7.1 4e-09 36.6 7.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KRH95235.1 - 2e-09 37.1 10.5 4.2e-09 36.1 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KRH95235.1 - 1e-07 31.5 9.3 2.5e-07 30.3 9.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KRH95235.1 - 8.4e-07 28.9 8.8 8.4e-07 28.9 8.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KRH95235.1 - 5.2e-06 26.2 6.8 1e-05 25.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH95235.1 - 4.2e-05 23.3 11.0 4.2e-05 23.3 11.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KRH95235.1 - 6.9e-05 22.6 6.8 0.00012 21.9 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KRH95235.1 - 0.00012 22.1 2.6 0.00027 20.9 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KRH95235.1 - 0.002 18.1 7.3 0.002 18.1 7.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Baculo_RING PF05883.11 KRH95235.1 - 0.042 13.8 1.7 0.085 12.8 1.7 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 KRH95235.1 - 0.26 11.1 7.5 0.58 10.0 7.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KRH95235.1 - 0.33 10.6 9.7 0.1 12.2 6.8 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type VIT1 PF01988.19 KRH95235.1 - 0.43 10.4 1.4 0.69 9.7 1.4 1.3 1 0 0 1 1 1 0 VIT family FANCL_C PF11793.8 KRH95235.1 - 0.71 10.1 9.4 3.5 7.9 9.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 KRH95235.1 - 0.72 9.8 6.8 1.7 8.6 3.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KRH95235.1 - 1.6 8.7 8.1 3.9 7.4 8.1 1.7 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KRH95235.1 - 2.1 8.5 13.2 0.36 11.0 9.5 1.7 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KRH95235.1 - 2.3 8.6 9.0 0.89 9.9 4.7 2.3 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.6 KRH95236.1 - 7.5e-10 39.0 6.5 1.1e-09 38.4 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KRH95236.1 - 1.2e-08 34.8 7.7 1.8e-08 34.2 7.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KRH95236.1 - 6.2e-08 32.2 2.4 6.2e-08 32.2 2.4 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KRH95236.1 - 2.8e-06 27.1 5.0 4.3e-06 26.5 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KRH95236.1 - 1.1e-05 25.1 5.6 1.8e-05 24.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH95236.1 - 1.1e-05 25.1 7.0 1.1e-05 25.1 7.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KRH95236.1 - 0.00015 22.0 6.7 0.00026 21.2 6.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KRH95236.1 - 0.00018 21.3 4.7 0.0004 20.2 4.8 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_9 PF13901.6 KRH95236.1 - 0.0002 21.4 6.2 0.00023 21.2 6.2 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-RING_UBOX PF13445.6 KRH95236.1 - 0.00042 20.3 3.3 0.00064 19.7 3.3 1.3 1 0 0 1 1 1 1 RING-type zinc-finger PHD PF00628.29 KRH95236.1 - 0.0028 17.5 9.2 0.0029 17.4 7.9 1.7 1 1 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.6 KRH95236.1 - 0.0056 16.4 7.1 0.011 15.5 7.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KRH95236.1 - 0.018 15.1 6.2 0.071 13.2 6.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KRH95236.1 - 0.12 12.0 5.6 0.12 12.0 4.4 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KRH95236.1 - 0.13 12.4 5.8 0.28 11.3 5.8 1.6 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_10 PF16685.5 KRH95236.1 - 0.17 12.1 8.6 0.67 10.1 7.3 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 Rtf2 PF04641.12 KRH95236.1 - 0.19 11.1 1.8 0.22 10.8 1.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-P11 PF03854.14 KRH95236.1 - 0.91 9.2 9.5 1.2 8.8 8.2 1.8 1 1 1 2 2 2 0 P-11 zinc finger zf-RING-like PF08746.11 KRH95236.1 - 7.8 6.9 13.1 26 5.2 13.1 1.8 1 1 0 1 1 1 0 RING-like domain Tup_N PF08581.10 KRH95238.1 - 0.12 12.7 0.8 0.53 10.6 0.8 2.2 1 1 1 2 2 2 0 Tup N-terminal JAB PF01398.21 KRH95241.1 - 2.6e-21 75.8 0.0 4.7e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KRH95241.1 - 0.027 14.9 0.2 0.058 13.8 0.1 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Tfb2 PF03849.14 KRH95242.1 - 2.8e-34 118.7 4.9 4e-34 118.1 4.9 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KRH95242.1 - 4e-20 72.0 1.0 7.1e-20 71.2 1.0 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KRH95242.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Eaf7 PF07904.13 KRH95243.1 - 0.024 15.0 0.2 0.037 14.4 0.2 1.3 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 CagY_M PF07337.11 KRH95244.1 - 0.068 12.8 0.6 0.21 11.3 0.6 1.8 1 0 0 1 1 1 0 DC-EC Repeat TFIID-18kDa PF02269.16 KRH95245.1 - 7.4e-21 74.0 0.2 2.8e-20 72.1 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Lactamase_B_2 PF12706.7 KRH95247.1 - 1e-14 54.5 0.0 2.8e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Brix PF04427.18 KRH95248.1 - 1.3e-07 31.9 2.3 2.4e-07 31.1 1.9 1.6 1 1 1 2 2 2 1 Brix domain DNA_photolyase PF00875.18 KRH95249.1 - 0.47 10.4 3.0 0.28 11.2 1.0 1.6 2 0 0 2 2 2 0 DNA photolyase COMP PF11598.8 KRH95249.1 - 0.72 10.4 6.1 2.2 8.8 0.7 3.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein ADIP PF11559.8 KRH95249.1 - 0.91 9.6 36.4 0.033 14.3 4.9 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KRH95249.1 - 1.1 9.7 20.8 0.42 11.0 0.5 4.7 5 0 0 5 5 5 0 TSC-22/dip/bun family DASH_Dad1 PF08649.10 KRH95249.1 - 3 8.1 7.1 0.31 11.2 1.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 SlyX PF04102.12 KRH95249.1 - 5.2 7.8 14.2 0.46 11.1 2.7 3.5 2 1 1 3 3 3 0 SlyX Myb_DNA-binding PF00249.31 KRH95250.1 - 3.8e-08 33.4 0.0 8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_S2 PF00318.20 KRH95252.1 - 7.2e-19 67.9 0.0 1.6e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Glycos_transf_1 PF00534.20 KRH95253.1 - 9.3e-15 54.6 0.0 3.3e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KRH95253.1 - 5.5e-10 39.8 0.0 9.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 HU-DNA_bdg PF14848.6 KRH95253.1 - 0.08 13.0 1.1 0.19 11.7 1.1 1.6 1 0 0 1 1 1 0 DNA-binding domain Glyco_trans_1_2 PF13524.6 KRH95253.1 - 0.095 13.1 0.1 0.82 10.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Mad3_BUB1_I_2 PF17014.5 KRH95254.1 - 3.3e-17 62.8 14.1 7.2e-16 58.5 2.9 4.7 2 2 2 4 4 4 3 Putative Mad3/BUB1 like region 1 protein DUF746 PF05344.11 KRH95254.1 - 0.13 12.1 0.1 0.46 10.4 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) PRTP PF01366.18 KRH95255.1 - 0.9 7.5 3.2 0.89 7.5 3.2 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Peroxin-3 PF04882.12 KRH95255.1 - 5.7 5.8 8.5 6.3 5.7 8.5 1.1 1 0 0 1 1 1 0 Peroxin-3 DNA_pol_B PF00136.21 KRH95256.1 - 4.5e-124 414.7 6.7 4.5e-124 414.7 6.7 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KRH95256.1 - 5.6e-49 167.1 20.1 7.6e-47 160.1 20.1 3.4 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KRH95256.1 - 1.8e-11 44.4 17.4 3.2e-11 43.5 14.9 2.5 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta TetR_C_26 PF17934.1 KRH95256.1 - 0.0068 16.7 1.5 0.032 14.6 0.5 2.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TIR-like PF10137.9 KRH95256.1 - 0.53 10.3 2.5 0.88 9.5 0.1 2.7 3 0 0 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain Helicase_C PF00271.31 KRH95257.1 - 2.6e-08 34.2 10.5 1.4e-07 31.9 0.1 4.4 5 0 0 5 5 5 2 Helicase conserved C-terminal domain DEAD PF00270.29 KRH95257.1 - 4.6e-07 29.8 1.8 7e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KRH95257.1 - 6.5e-06 26.4 1.0 0.00033 21.0 0.1 2.9 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KRH95257.1 - 0.0001 22.5 0.7 0.0001 22.5 0.7 4.1 2 2 0 2 2 2 1 Helicase associated domain (HA2) T2SSE PF00437.20 KRH95257.1 - 0.0006 19.0 0.1 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 KRH95257.1 - 0.0019 18.1 1.4 0.039 13.8 0.0 3.0 3 0 0 3 3 3 1 Helicase AAA_7 PF12775.7 KRH95257.1 - 0.0019 17.7 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KRH95257.1 - 0.015 15.6 0.1 0.091 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KRH95257.1 - 0.17 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAM76 PF16046.5 KRH95258.1 - 0.12 11.7 22.5 0.25 10.6 22.5 1.5 1 0 0 1 1 1 0 FAM76 protein LCIB_C_CA PF18599.1 KRH95258.1 - 0.25 10.6 1.5 0.51 9.6 1.5 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DHHC PF01529.20 KRH95259.1 - 7e-28 97.4 13.3 7e-28 97.4 13.3 2.9 2 1 0 2 2 2 2 DHHC palmitoyltransferase ZapB PF06005.12 KRH95259.1 - 0.019 15.4 5.3 0.019 15.4 5.3 4.5 2 1 3 5 5 5 0 Cell division protein ZapB Atrophin-1 PF03154.15 KRH95259.1 - 0.46 8.7 23.6 0.6 8.3 23.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DHHC PF01529.20 KRH95261.1 - 3.8e-27 95.0 17.1 3.8e-27 95.0 17.1 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase tRNA-synt_2 PF00152.20 KRH95264.1 - 2.3e-80 270.0 0.1 3.1e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KRH95264.1 - 1.3e-11 44.3 0.1 2.6e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KRH95264.1 - 1.7e-09 37.5 0.7 9.1e-06 25.3 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Phage_term_sma PF07141.11 KRH95265.1 - 0.011 15.5 0.0 0.038 13.8 0.0 1.8 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit zf-AN1 PF01428.16 KRH95266.1 - 6.6e-07 29.4 13.7 1.2e-06 28.6 13.7 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger PAXIP1_C PF15364.6 KRH95266.1 - 0.059 13.7 4.5 0.091 13.1 4.5 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Yippee-Mis18 PF03226.14 KRH95266.1 - 0.17 12.1 7.8 0.29 11.4 7.8 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L10 PF00466.20 KRH95267.1 - 3e-16 59.4 2.5 5.8e-16 58.5 2.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 FlhD PF05247.13 KRH95267.1 - 0.028 14.7 0.0 0.096 13.0 0.0 1.8 1 1 0 2 2 2 0 Flagellar transcriptional activator (FlhD) DUF2721 PF11026.8 KRH95270.1 - 0.0085 16.0 0.1 0.0086 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF2207 PF09972.9 KRH95270.1 - 0.035 12.9 0.8 0.036 12.8 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_C50 PF03568.17 KRH95271.1 - 2.3e-21 76.4 9.0 6.5e-12 45.3 0.0 3.7 2 1 2 4 4 4 3 Peptidase family C50 CHAT PF12770.7 KRH95271.1 - 0.24 10.7 0.0 0.98 8.8 0.0 1.8 2 0 0 2 2 2 0 CHAT domain Ssl1 PF04056.14 KRH95272.1 - 2.5e-20 73.1 0.1 3.5e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like Proteasome PF00227.26 KRH95273.1 - 2.5e-20 72.8 0.0 3e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MMU163 PF17119.5 KRH95274.1 - 0.034 13.3 0.4 0.055 12.6 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis V-ATPase_H_C PF11698.8 KRH95274.1 - 0.09 12.9 5.7 1.1 9.3 1.8 3.0 2 1 1 3 3 3 0 V-ATPase subunit H SpoVIF PF14069.6 KRH95274.1 - 0.1 12.4 5.6 5.6 6.8 0.1 3.0 3 0 0 3 3 3 0 Stage VI sporulation protein F RTP1_C1 PF10363.9 KRH95274.1 - 0.16 12.1 3.0 0.85 9.8 1.3 2.3 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Sld5 PF05916.11 KRH95275.1 - 1.3e-08 35.2 0.3 1.9e-08 34.8 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4201 PF13870.6 KRH95277.1 - 0.00081 19.2 13.6 0.001 18.9 13.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Med9 PF07544.13 KRH95277.1 - 0.0037 17.3 8.7 0.3 11.2 0.7 2.2 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Golgin_A5 PF09787.9 KRH95277.1 - 0.015 14.8 14.9 0.016 14.7 14.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Vps4_C PF09336.10 KRH95277.1 - 0.016 15.2 2.6 0.12 12.4 0.2 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF1664 PF07889.12 KRH95277.1 - 0.025 14.6 9.1 0.044 13.8 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KRH95277.1 - 0.038 14.4 9.5 0.046 14.2 9.5 1.1 1 0 0 1 1 1 0 Fez1 Phage_GP20 PF06810.11 KRH95277.1 - 0.057 13.2 15.9 0.5 10.2 6.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KRH95277.1 - 0.097 13.1 7.5 1.2 9.6 0.3 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SpecificRecomb PF10136.9 KRH95277.1 - 0.1 10.9 1.0 0.12 10.7 1.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase SlyX PF04102.12 KRH95277.1 - 0.12 13.0 11.2 0.46 11.1 4.1 2.3 1 1 1 2 2 2 0 SlyX DUF641 PF04859.12 KRH95277.1 - 0.16 12.3 9.8 2.4 8.5 1.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cob_adeno_trans PF01923.18 KRH95277.1 - 0.17 12.0 1.7 0.24 11.5 1.7 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase ArAE_2_N PF10337.9 KRH95277.1 - 0.22 10.5 1.8 0.37 9.8 1.8 1.5 1 1 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Prominin PF05478.11 KRH95277.1 - 0.23 9.4 8.9 0.26 9.2 8.9 1.0 1 0 0 1 1 1 0 Prominin ALMT PF11744.8 KRH95277.1 - 0.27 10.0 9.0 0.31 9.8 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Bcr-Abl_Oligo PF09036.10 KRH95277.1 - 0.27 11.2 2.5 0.84 9.7 0.4 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain SDH_alpha PF03313.15 KRH95277.1 - 0.31 10.7 1.6 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Serine dehydratase alpha chain V_ATPase_I PF01496.19 KRH95277.1 - 0.32 8.9 10.9 0.36 8.7 10.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 KRH95277.1 - 0.33 10.5 7.0 0.4 10.2 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 KRH95277.1 - 0.33 10.7 8.0 2.6 7.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 KRH95277.1 - 0.42 11.3 10.5 0.86 10.3 3.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 KRH95277.1 - 0.54 9.1 15.8 1.4 7.7 15.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.11 KRH95277.1 - 0.96 9.7 4.6 41 4.5 4.6 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HNOBA PF07701.14 KRH95277.1 - 1.2 8.6 9.6 2.8 7.3 2.8 2.3 1 1 1 2 2 2 0 Heme NO binding associated DUF2802 PF10975.8 KRH95277.1 - 1.2 9.3 6.9 4.2 7.6 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Allexi_40kDa PF05549.11 KRH95277.1 - 1.5 8.2 8.9 4.7 6.6 8.9 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 KRH95277.1 - 3.5 7.5 11.2 8.9 6.2 5.6 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.6 KRH95277.1 - 4.4 6.6 6.5 5.4 6.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.9 KRH95277.1 - 5.5 7.6 12.2 6.6 7.4 11.5 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SRP_TPR_like PF17004.5 KRH95278.1 - 1.7e-05 24.8 0.1 2e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Putative TPR-like repeat DUF1664 PF07889.12 KRH95279.1 - 0.00035 20.6 3.7 0.00044 20.3 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KRH95279.1 - 0.00064 20.0 5.4 0.0036 17.6 3.2 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KRH95279.1 - 0.00073 20.0 0.6 0.007 16.8 0.2 2.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 KRH95279.1 - 0.0013 18.6 5.0 0.16 11.8 0.0 2.0 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 1 DASH_Duo1 PF08651.10 KRH95279.1 - 0.0019 18.0 2.3 0.0093 15.7 0.5 2.3 2 1 0 2 2 2 1 DASH complex subunit Duo1 DUF812 PF05667.11 KRH95279.1 - 0.01 14.7 9.5 0.011 14.7 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Trimer_CC PF08954.11 KRH95279.1 - 0.029 13.9 1.3 0.12 11.9 0.3 2.2 2 0 0 2 2 2 0 Trimerisation motif FapA PF03961.13 KRH95279.1 - 0.035 12.7 7.2 0.041 12.5 7.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A BDV_P24 PF06595.11 KRH95279.1 - 0.042 13.7 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein DUF948 PF06103.11 KRH95279.1 - 0.062 13.6 0.8 3.3 8.0 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.11 KRH95279.1 - 0.12 11.9 3.0 0.14 11.6 3.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Rx_N PF18052.1 KRH95279.1 - 0.15 12.4 6.0 3.4 8.0 0.2 2.1 1 1 1 2 2 2 0 Rx N-terminal domain EMP24_GP25L PF01105.24 KRH95279.1 - 0.16 11.9 4.3 0.21 11.5 4.3 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 KRH95279.1 - 0.23 12.0 6.2 0.87 10.1 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Sec20 PF03908.13 KRH95279.1 - 0.66 9.9 3.6 0.96 9.4 2.0 1.8 1 1 1 2 2 2 0 Sec20 Fib_alpha PF08702.10 KRH95279.1 - 0.95 9.6 7.3 0.55 10.4 2.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ALMT PF11744.8 KRH95279.1 - 1.1 8.0 6.7 1.3 7.8 6.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter YabA PF06156.13 KRH95279.1 - 1.3 9.7 8.3 0.57 10.8 4.8 1.9 1 1 1 2 2 2 0 Initiation control protein YabA SRP_TPR_like PF17004.5 KRH95280.1 - 1e-36 125.5 9.1 2.1e-36 124.4 9.1 1.6 1 0 0 1 1 1 1 Putative TPR-like repeat ANAPC3 PF12895.7 KRH95280.1 - 1.6e-05 25.0 9.6 0.00012 22.2 6.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KRH95280.1 - 0.0003 20.7 3.4 0.53 10.5 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KRH95280.1 - 0.0011 19.5 0.3 0.17 12.4 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KRH95280.1 - 0.011 15.5 6.3 1.1 9.2 1.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KRH95280.1 - 0.014 15.6 5.0 0.073 13.3 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat GreA_GreB_N PF03449.15 KRH95280.1 - 0.019 15.1 0.0 0.077 13.2 0.0 2.1 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal TPR_12 PF13424.6 KRH95280.1 - 0.15 12.4 0.5 7.2 7.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat NES_C_h PF18208.1 KRH95280.1 - 1.3 9.3 7.7 0.19 12.0 2.7 2.2 2 1 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain tRNA-synt_1g PF09334.11 KRH95281.1 - 1.1e-112 376.7 11.1 2e-57 194.7 5.4 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KRH95281.1 - 7.9e-08 31.0 0.3 0.00075 17.9 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DUF5644 PF18712.1 KRH95281.1 - 0.0021 18.0 0.4 0.0081 16.2 0.3 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5644) DUF393 PF04134.12 KRH95281.1 - 0.035 15.4 0.0 1 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF393 Anticodon_1 PF08264.13 KRH95281.1 - 0.042 13.8 0.2 0.042 13.8 0.2 2.4 3 0 0 3 3 3 0 Anticodon-binding domain of tRNA MqsA_antitoxin PF15731.5 KRH95281.1 - 0.24 11.5 5.2 4 7.6 1.3 2.7 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Laminin_EGF PF00053.24 KRH95281.1 - 3.7 7.8 8.0 11 6.3 8.0 1.8 1 0 0 1 1 1 0 Laminin EGF domain DZR PF12773.7 KRH95281.1 - 5.7 7.0 11.6 1.5e+02 2.5 9.2 3.4 2 1 0 2 2 2 0 Double zinc ribbon Bacillus_HBL PF05791.11 KRH95282.1 - 0.045 13.6 2.1 0.18 11.6 1.2 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) RecG_N PF17190.4 KRH95282.1 - 0.31 11.8 7.6 3.6 8.4 0.2 3.7 1 1 1 3 3 3 0 RecG N-terminal helical domain Amidase PF01425.21 KRH95283.1 - 0.065 12.2 0.0 0.072 12.0 0.0 1.0 1 0 0 1 1 1 0 Amidase RyR PF02026.16 KRH95285.1 - 0.11 12.7 1.2 0.28 11.4 1.2 1.7 1 0 0 1 1 1 0 RyR domain Holin_BhlA PF10960.8 KRH95285.1 - 6.1 6.9 7.9 0.44 10.6 0.9 2.7 3 0 0 3 3 3 0 BhlA holin family Chordopox_A33R PF05966.12 KRH95287.1 - 0.041 13.2 0.4 0.064 12.5 0.4 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein OST_P2 PF18235.1 KRH95288.1 - 0.067 13.1 4.1 0.22 11.5 2.9 2.5 1 1 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain Tfb5 PF06331.12 KRH95289.1 - 9e-08 32.0 0.1 1.1e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 zf-C2H2_jaz PF12171.8 KRH95290.1 - 0.0014 18.8 2.0 0.0014 18.8 2.0 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KRH95290.1 - 0.0062 16.9 3.4 0.017 15.5 3.4 1.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Tmemb_55A PF09788.9 KRH95290.1 - 0.052 12.6 0.2 0.073 12.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A zf-C2H2_4 PF13894.6 KRH95290.1 - 0.059 14.2 1.1 0.059 14.2 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-MYST PF17772.1 KRH95290.1 - 0.096 12.3 0.4 0.096 12.3 0.4 1.7 2 0 0 2 2 2 0 MYST family zinc finger domain DUF4407 PF14362.6 KRH95290.1 - 0.35 10.2 2.7 0.47 9.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-met PF12874.7 KRH95290.1 - 2.8 8.5 10.6 0.23 11.9 1.0 3.0 2 1 0 2 2 2 0 Zinc-finger of C2H2 type ATP-synt_C PF00137.21 KRH95291.1 - 1.6e-06 28.3 2.7 1.6e-06 28.3 2.7 2.2 2 0 0 2 2 2 1 ATP synthase subunit C DUF2975 PF11188.8 KRH95291.1 - 0.35 10.8 5.8 0.47 10.3 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF155 PF02582.14 KRH95293.1 - 4.6e-44 150.6 0.8 9.4e-44 149.6 0.8 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 eIF-5_eIF-2B PF01873.17 KRH95294.1 - 3e-25 88.4 0.7 8.2e-25 87.0 0.1 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Peptidase_C65 PF10275.9 KRH95296.1 - 2.9e-11 43.3 6.5 1.3e-07 31.3 6.5 3.0 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KRH95296.1 - 0.013 16.0 0.6 0.57 10.7 0.0 2.3 1 1 1 2 2 2 0 OTU-like cysteine protease OSK PF17182.4 KRH95299.1 - 0.029 13.6 3.8 0.062 12.5 3.8 1.5 1 0 0 1 1 1 0 OSK domain DUF5063 PF16702.5 KRH95299.1 - 0.036 14.5 2.1 0.059 13.8 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5063) Mer2 PF09074.10 KRH95299.1 - 0.16 11.7 10.0 0.57 10.0 4.2 2.3 2 0 0 2 2 2 0 Mer2 Syntaxin_2 PF14523.6 KRH95299.1 - 7.2 7.0 8.4 19 5.7 0.0 3.3 2 1 1 3 3 3 0 Syntaxin-like protein DcpS_C PF11969.8 KRH95300.1 - 9.1e-15 55.1 1.3 9.1e-15 55.1 1.3 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Herpes_BLLF1 PF05109.13 KRH95300.1 - 6.9e-06 24.4 16.6 9.1e-06 24.0 16.6 1.1 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Pirin_C_2 PF17954.1 KRH95300.1 - 0.25 11.5 1.2 1.3 9.2 1.2 2.2 1 1 0 1 1 1 0 Quercetinase C-terminal cupin domain DUF948 PF06103.11 KRH95300.1 - 0.4 11.0 20.4 0.81 10.0 4.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PDDEXK_6 PF04720.12 KRH95300.1 - 0.49 10.3 6.2 0.84 9.5 6.2 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DcpS PF05652.12 KRH95300.1 - 1.8 9.5 13.8 67 4.4 13.8 3.3 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2981 PF11200.8 KRH95300.1 - 4 7.1 9.2 5.4 6.7 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Dopey_N PF04118.14 KRH95301.1 - 1.4e-31 109.8 23.8 2.5e-30 105.7 2.4 5.7 4 1 1 5 5 5 3 Dopey, N-terminal PK PF00224.21 KRH95303.1 - 3.3e-97 325.5 13.7 5.8e-51 173.4 0.1 2.3 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 KRH95303.1 - 2.2e-05 23.7 0.1 0.0002 20.6 0.1 2.1 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Otopetrin PF03189.13 KRH95303.1 - 0.086 11.6 0.7 1 8.1 0.7 2.3 1 1 0 1 1 1 0 Otopetrin DUF4279 PF14106.6 KRH95303.1 - 0.12 12.6 2.7 6.9 6.9 0.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Death PF00531.22 KRH95303.1 - 0.19 11.9 3.5 13 6.0 0.3 2.8 1 1 2 3 3 3 0 Death domain DUF5595 PF18077.1 KRH95303.1 - 1.5 8.9 6.1 19 5.4 0.3 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) CPSase_L_D3 PF02787.19 KRH95303.1 - 2.8 8.3 6.9 48 4.3 3.6 3.5 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF465 PF04325.13 KRH95303.1 - 5.2 7.2 6.4 55 3.9 0.7 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF465) ArlS_N PF18719.1 KRH95304.1 - 0.017 15.3 3.3 0.034 14.4 3.3 1.5 1 0 0 1 1 1 0 ArlS sensor domain Ribosomal_L37e PF01907.19 KRH95306.1 - 1.7e-17 63.3 13.7 3.2e-17 62.4 13.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KRH95306.1 - 0.024 14.6 2.8 0.039 14.0 2.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2387 PF09526.10 KRH95306.1 - 0.037 14.2 4.3 0.11 12.6 0.7 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-RING_5 PF14634.6 KRH95306.1 - 0.068 13.1 4.4 0.11 12.5 4.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 KRH95306.1 - 0.18 11.6 1.0 0.18 11.6 1.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KRH95306.1 - 0.21 11.5 5.6 0.32 10.9 5.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KRH95306.1 - 0.41 10.6 7.0 0.71 9.8 7.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1258 PF06869.12 KRH95306.1 - 3.5 7.1 9.4 1.5 8.3 4.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) SOG2 PF10428.9 KRH95307.1 - 0.00039 19.8 31.3 0.00064 19.0 31.3 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein FANCD2OS PF15124.6 KRH95307.1 - 0.65 10.2 4.3 1.1 9.5 0.7 2.7 2 1 0 2 2 2 0 FANCD2 opposite strand protein Bac_rhamnosid PF05592.11 KRH95308.1 - 0.067 13.2 7.0 10 6.2 0.2 3.7 1 1 3 4 4 4 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain M60-like_N PF17291.2 KRH95308.1 - 4.9 7.1 6.2 14 5.7 0.3 3.2 1 1 2 3 3 3 0 N-terminal domain of M60-like peptidases DUF4131 PF13567.6 KRH95309.1 - 0.44 10.2 2.7 0.55 9.9 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2070 PF09843.9 KRH95309.1 - 1 7.6 8.6 1.1 7.4 8.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VirB3 PF05101.13 KRH95309.1 - 4 7.7 8.2 4.5 7.6 7.6 1.4 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Choline_kin_N PF04428.14 KRH95310.1 - 0.042 13.5 2.8 0.5 10.1 0.2 2.0 2 0 0 2 2 2 0 Choline kinase N terminus AAA_18 PF13238.6 KRH95311.1 - 1.2e-10 42.1 1.6 2.2e-10 41.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KRH95311.1 - 2e-05 24.9 0.0 3.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KRH95311.1 - 7e-05 23.3 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KRH95311.1 - 0.00012 22.5 5.0 0.00057 20.3 0.1 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KRH95311.1 - 0.00013 21.7 0.2 0.00023 20.9 0.2 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KRH95311.1 - 0.00032 20.5 0.1 0.00048 19.9 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KRH95311.1 - 0.0012 18.0 0.4 0.0018 17.4 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 KRH95311.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KRH95311.1 - 0.0037 17.0 0.2 0.0037 17.0 0.2 1.9 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 KRH95311.1 - 0.0038 16.7 0.3 0.0095 15.4 0.1 1.8 1 1 1 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 KRH95311.1 - 0.004 16.5 0.1 0.004 16.5 0.1 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KRH95311.1 - 0.0045 17.3 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain dNK PF01712.19 KRH95311.1 - 0.0047 16.8 1.5 1.7 8.5 0.1 2.5 2 0 0 2 2 2 2 Deoxynucleoside kinase KTI12 PF08433.10 KRH95311.1 - 0.0053 16.3 1.7 0.0081 15.6 0.0 2.0 1 1 1 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KRH95311.1 - 0.0068 16.8 0.5 0.021 15.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 KRH95311.1 - 0.0075 16.2 0.2 0.0075 16.2 0.2 1.7 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 KRH95311.1 - 0.0098 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KRH95311.1 - 0.014 15.4 0.1 0.036 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KRH95311.1 - 0.015 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KRH95311.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KRH95311.1 - 0.018 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KRH95311.1 - 0.02 14.4 0.2 0.032 13.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KRH95311.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CbiA PF01656.23 KRH95311.1 - 0.023 14.7 0.5 0.06 13.4 0.5 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KRH95311.1 - 0.027 14.4 0.2 0.076 12.9 0.2 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.6 KRH95311.1 - 0.03 14.7 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KRH95311.1 - 0.035 14.0 2.2 0.068 13.1 2.2 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KRH95311.1 - 0.047 13.3 0.1 0.073 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KRH95311.1 - 0.048 13.4 0.1 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KRH95311.1 - 0.071 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KRH95311.1 - 0.085 13.0 0.0 0.085 13.0 0.0 2.4 2 1 1 3 3 3 0 Shikimate kinase AAA_3 PF07726.11 KRH95311.1 - 0.089 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KRH95311.1 - 0.11 11.4 1.4 0.14 11.1 0.4 1.7 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Hydin_ADK PF17213.3 KRH95311.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NB-ARC PF00931.22 KRH95311.1 - 0.74 9.0 4.9 0.43 9.7 0.1 2.2 2 1 1 3 3 3 0 NB-ARC domain Zip PF02535.22 KRH95311.1 - 3.5 6.7 6.4 3.9 6.6 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lectin_leg-like PF03388.13 KRH95317.1 - 0.0018 17.6 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Legume-like lectin family CCDC-167 PF15188.6 KRH95317.1 - 0.034 14.5 0.3 0.087 13.2 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Trimer_CC PF08954.11 KRH95317.1 - 0.13 11.8 0.1 0.93 9.1 0.1 2.2 2 0 0 2 2 2 0 Trimerisation motif ERCC4 PF02732.15 KRH95318.1 - 3.6e-12 46.8 1.1 3.6e-12 46.8 1.1 3.2 3 1 0 3 3 3 1 ERCC4 domain 2H-phosphodiest PF08975.10 KRH95318.1 - 0.1 12.5 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) Kinesin PF00225.23 KRH95319.1 - 4.8e-69 232.8 9.6 4.8e-69 232.8 9.6 3.2 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KRH95319.1 - 4.3e-22 78.7 1.4 9.6e-20 71.0 0.3 4.2 3 1 0 3 3 3 2 Microtubule binding DUF2187 PF09953.9 KRH95319.1 - 0.1 12.6 2.1 0.9 9.6 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) UPF0184 PF03670.13 KRH95319.1 - 0.36 11.2 0.1 0.36 11.2 0.1 3.6 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) EF-hand_6 PF13405.6 KRH95320.1 - 0.049 13.6 1.2 1.2 9.3 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain Herpes_TK PF00693.18 KRH95320.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus RNA_pol_N PF01194.17 KRH95322.1 - 3e-25 88.3 2.4 3.4e-25 88.1 2.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit NUDIX PF00293.28 KRH95324.1 - 1.3e-09 38.2 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 KRH95324.1 - 2.5e-09 37.3 4.8 3.6e-09 36.8 2.9 2.3 2 0 0 2 2 2 1 Dcp2, box A domain Diphthamide_syn PF01866.17 KRH95325.1 - 9.8e-14 51.5 1.7 1.5e-13 50.9 1.7 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Glutaredoxin PF00462.24 KRH95327.1 - 3e-05 24.2 0.1 8.5e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin Apolipoprotein PF01442.18 KRH95327.1 - 0.0005 20.0 0.3 0.00097 19.1 0.3 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KRH95327.1 - 0.014 15.9 3.1 0.018 15.7 0.3 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KRH95327.1 - 0.017 15.7 15.5 22 5.7 15.5 3.2 1 1 0 1 1 1 0 YtxH-like protein ApoA-II PF04711.13 KRH95327.1 - 0.12 12.6 1.9 0.96 9.6 0.2 2.4 1 1 1 2 2 2 0 Apolipoprotein A-II (ApoA-II) MT0933_antitox PF14013.6 KRH95327.1 - 0.15 12.4 5.0 0.3 11.4 2.2 2.6 1 1 1 2 2 2 0 MT0933-like antitoxin protein YkyA PF10368.9 KRH95327.1 - 0.4 10.3 16.6 0.018 14.7 10.6 1.8 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein ApoLp-III PF07464.11 KRH95327.1 - 3.1 7.9 15.7 4.7 7.3 7.1 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.14 KRH95327.1 - 4 7.8 12.5 0.1 12.9 2.3 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DASH_Spc19 PF08287.11 KRH95327.1 - 6.6 6.6 9.2 1.4 8.8 4.2 2.1 1 1 2 3 3 3 0 Spc19 EAF PF09816.9 KRH95328.1 - 0.16 12.4 4.7 0.089 13.2 0.7 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription elongation factor NIF3 PF01784.18 KRH95329.1 - 1.1e-43 149.7 0.6 1.3e-43 149.4 0.6 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) UPF0160 PF03690.13 KRH95330.1 - 9.2e-79 265.3 0.5 1.3e-78 264.9 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) EST1 PF10374.9 KRH95330.1 - 0.066 13.9 0.5 0.13 12.9 0.4 1.6 1 1 0 1 1 1 0 Telomerase activating protein Est1 Sec20 PF03908.13 KRH95331.1 - 4.3e-05 23.4 0.3 0.0001 22.2 0.1 1.7 1 1 1 2 2 2 1 Sec20 Synaptobrevin PF00957.21 KRH95331.1 - 0.00098 18.9 2.8 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 Synaptobrevin Prominin PF05478.11 KRH95331.1 - 0.013 13.5 1.3 0.014 13.4 1.3 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.9 KRH95331.1 - 0.037 13.0 3.0 0.05 12.6 2.2 1.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Insulin_TMD PF17870.1 KRH95331.1 - 0.077 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SAS4 PF15460.6 KRH95331.1 - 0.32 11.1 4.4 0.9 9.7 4.2 1.8 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 IFN-gamma PF00714.17 KRH95331.1 - 1.1 9.1 7.2 0.91 9.4 1.3 2.7 1 1 2 3 3 3 0 Interferon gamma AAA PF00004.29 KRH95332.1 - 3.6e-42 143.9 0.0 7.8e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KRH95332.1 - 6e-12 45.2 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KRH95332.1 - 3.9e-08 33.1 0.4 9.3e-08 31.9 0.4 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KRH95332.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KRH95332.1 - 2.1e-05 24.8 0.3 0.034 14.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KRH95332.1 - 2.7e-05 23.5 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KRH95332.1 - 0.00028 20.9 0.1 0.0015 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KRH95332.1 - 0.00041 20.1 0.0 0.00086 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KRH95332.1 - 0.0011 19.4 0.3 0.009 16.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 KRH95332.1 - 0.0013 18.4 0.1 0.0033 17.0 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KRH95332.1 - 0.0046 16.3 0.1 0.25 10.7 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 KRH95332.1 - 0.0069 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KRH95332.1 - 0.0071 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KRH95332.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KRH95332.1 - 0.027 15.0 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KRH95332.1 - 0.032 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KRH95332.1 - 0.044 13.0 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KRH95332.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KRH95332.1 - 0.08 12.7 0.5 0.31 10.7 0.5 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KRH95332.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KRH95332.1 - 0.098 11.8 0.0 0.65 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KRH95332.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KRH95332.1 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Piwi PF02171.17 KRH95333.1 - 0.0065 15.8 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Piwi domain Methyltransf_8 PF05148.15 KRH95334.1 - 6.8e-41 140.5 6.5 6.6e-31 107.9 0.1 3.2 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KRH95334.1 - 6.9e-08 33.0 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KRH95334.1 - 9.5e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KRH95334.1 - 9.5e-06 26.2 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KRH95334.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KRH95334.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KRH95334.1 - 0.0039 16.7 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KRH95334.1 - 0.0047 17.6 0.6 0.01 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Lys PF00062.20 KRH95334.1 - 0.01 16.0 0.8 0.035 14.4 0.1 2.0 1 1 1 2 2 2 0 C-type lysozyme/alpha-lactalbumin family Herpes_U15 PF05613.11 KRH95334.1 - 0.012 16.3 0.4 0.044 14.5 0.0 1.9 2 0 0 2 2 2 0 Human herpesvirus U15 protein U71 PF17474.2 KRH95334.1 - 0.058 13.3 1.2 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Tegument protein UL11 homolog ANAPC10 PF03256.16 KRH95335.1 - 1.3e-21 77.0 0.2 3.5e-21 75.7 0.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 KRH95335.1 - 0.022 15.0 0.1 0.093 12.9 0.1 1.8 1 1 0 1 1 1 0 PITH domain SH2_2 PF14633.6 KRH95337.1 - 0.00065 19.2 1.3 0.0053 16.2 0.1 2.8 3 0 0 3 3 3 1 SH2 domain Ribosomal_S5 PF00333.20 KRH95338.1 - 3.2e-23 81.5 2.3 5.4e-23 80.7 2.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KRH95338.1 - 1.9e-22 78.5 0.0 3e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SWIRM-assoc_1 PF16495.5 KRH95339.1 - 0.001 19.0 10.1 0.001 19.0 10.1 2.4 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 KRH95339.1 - 0.0089 16.3 0.7 0.024 14.9 0.0 2.1 2 0 0 2 2 1 1 Myb-like DNA-binding domain YojJ PF10372.9 KRH95339.1 - 0.026 14.6 2.6 1.6 8.9 0.4 3.5 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus SWIRM PF04433.17 KRH95339.1 - 0.034 14.5 5.6 0.036 14.4 2.1 3.0 2 1 0 2 2 2 0 SWIRM domain ACP_PD PF04336.12 KRH95339.1 - 0.064 13.7 7.5 3.6 8.1 0.2 3.6 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase DASH_Dad1 PF08649.10 KRH95339.1 - 0.067 13.4 8.5 0.14 12.3 2.4 3.6 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF4428 PF14471.6 KRH95339.1 - 0.11 12.5 10.8 0.26 11.3 7.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DASH_Duo1 PF08651.10 KRH95339.1 - 0.68 9.8 11.5 0.068 12.9 2.7 3.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 SNARE PF05739.19 KRH95339.1 - 1.1 9.3 4.8 0.81 9.7 2.3 2.1 2 0 0 2 2 2 0 SNARE domain DUF948 PF06103.11 KRH95339.1 - 1.5 9.1 3.8 6.7 7.0 3.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0184 PF03670.13 KRH95339.1 - 3.2 8.2 13.8 0.095 13.1 5.1 2.7 2 1 0 3 3 2 0 Uncharacterised protein family (UPF0184) ARID PF01388.21 KRH95341.1 - 2.6e-11 44.1 0.2 1.4e-10 41.7 0.2 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Chromo PF00385.24 KRH95341.1 - 0.088 12.7 5.3 4.2 7.3 1.8 3.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain CTD PF12815.7 KRH95341.1 - 8.7 7.0 10.9 33 5.1 10.9 1.8 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 VPS9 PF02204.18 KRH95342.1 - 0.00034 20.8 8.9 0.016 15.4 1.6 4.2 4 1 0 4 4 4 1 Vacuolar sorting protein 9 (VPS9) domain APOBEC1 PF18769.1 KRH95342.1 - 0.071 13.4 0.3 0.071 13.4 0.3 3.1 3 0 0 3 3 3 0 APOBEC1 DUF4145 PF13643.6 KRH95342.1 - 0.68 10.1 6.2 0.2 11.8 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF4413 PF14372.6 KRH95344.1 - 0.037 14.4 0.1 0.05 14.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) SRF-TF PF00319.18 KRH95345.1 - 3e-19 68.2 0.2 4.7e-19 67.6 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.6 KRH95345.1 - 0.085 13.0 1.1 0.19 11.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) WD40_like PF17005.5 KRH95346.1 - 2.8e-08 33.4 30.2 6.2e-05 22.5 5.1 5.2 1 1 2 4 4 4 4 WD40-like domain ANAPC4_WD40 PF12894.7 KRH95346.1 - 7.5e-05 23.0 0.0 0.32 11.3 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KRH95346.1 - 0.0012 19.7 0.6 0.0094 16.8 0.1 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat RicinB_lectin_2 PF14200.6 KRH95347.1 - 0.0045 17.7 0.0 0.076 13.7 0.0 2.7 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Peptidase_S30 PF01577.16 KRH95347.1 - 0.01 15.5 1.0 0.014 15.0 1.0 1.2 1 0 0 1 1 1 1 Potyvirus P1 protease Tau95 PF09734.9 KRH95348.1 - 7.5e-13 49.5 1.3 1.9e-12 48.2 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain MAP65_ASE1 PF03999.12 KRH95352.1 - 1.1e-10 40.8 15.3 1.1e-10 40.8 15.3 3.4 1 1 1 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Pseudoloma_neurophilia-ASM143216v1/GCA_001432165.1_ASM143216v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Pseudoloma_neurophilia-ASM143216v1/GCA_001432165.1_ASM143216v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Pseudoloma_neurophilia-ASM143216v1/GCA_001432165.1_ASM143216v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Pseudoloma_neurophilia-ASM143216v1/GCA_001432165.1_ASM143216v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 09:07:25 2019 # [ok]