# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2723 PF11028.3 KRH91709.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF1240 PF06836.7 KRH91710.1 - 0.25 11.5 1.4 11 6.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) rve PF00665.21 KRH91712.1 - 8.7e-23 80.7 0.0 1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH91712.1 - 0.0007 19.0 0.0 0.003 17.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF4358 PF14270.1 KRH91713.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DUF2481 PF10654.4 KRH91713.1 - 0.099 12.3 5.8 0.11 12.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) Spt20 PF12090.3 KRH91713.1 - 0.16 11.3 2.0 0.25 10.6 1.4 1.6 1 1 0 1 1 1 0 Spt20 family Sirohm_synth_C PF14823.1 KRH91713.1 - 0.25 10.6 2.4 0.42 9.9 0.4 2.2 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal RVT_1 PF00078.22 KRH91714.1 - 1.8e-09 37.3 0.2 3.4e-09 36.3 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Carboxyl_trans PF01039.17 KRH91716.1 - 5.7e-13 48.0 0.0 5.9e-13 47.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain WD40 PF00400.27 KRH91717.1 - 1.1e-08 34.6 0.4 1.4e-07 31.1 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat RNA_pol_Rpb1_5 PF04998.12 KRH91718.1 - 6.7e-30 104.2 0.2 9.8e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 KRH91718.1 - 1.9e-27 95.1 0.2 3.2e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Toprim PF01751.17 KRH91719.1 - 6.7e-20 70.9 0.1 9.6e-20 70.4 0.1 1.2 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 KRH91719.1 - 0.00044 20.2 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 KRH91719.1 - 0.033 14.5 0.1 0.069 13.4 0.1 1.6 1 1 0 1 1 1 0 Toprim-like UDPGP PF01704.13 KRH91721.1 - 3.5e-08 32.3 0.1 4.1e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KRH91721.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain DEAD PF00270.24 KRH91722.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase RVP_2 PF08284.6 KRH91723.1 - 2.6e-07 30.6 0.1 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH91723.1 - 3.5e-05 23.5 0.0 0.00021 21.0 0.0 1.9 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH91723.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH91723.1 - 0.0014 18.1 0.1 0.004 16.7 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KRH91723.1 - 0.0033 17.8 0.0 0.0049 17.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RNA_pol_Rpb2_6 PF00562.23 KRH91724.1 - 7.4e-22 77.6 0.4 7.4e-22 77.6 0.3 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 DUF3533 PF12051.3 KRH91724.1 - 0.022 13.4 2.0 0.026 13.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) RVT_1 PF00078.22 KRH91725.1 - 7.5e-08 31.9 0.0 8e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2846 PF11008.3 KRH91726.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2846) SAD_SRA PF02182.12 KRH91726.1 - 0.017 14.4 1.0 0.023 14.0 0.7 1.1 1 0 0 1 1 1 0 SAD/SRA domain Sld5 PF05916.6 KRH91726.1 - 0.062 13.5 2.7 0.12 12.6 1.6 1.7 1 1 1 2 2 2 0 GINS complex protein YolD PF08863.5 KRH91726.1 - 1.3 8.9 7.0 0.3 10.9 1.3 2.2 1 1 1 2 2 2 0 YolD-like protein PSP1 PF04468.7 KRH91731.1 - 1.2e-25 89.3 1.8 1.6e-25 88.8 1.2 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF950 PF06106.6 KRH91731.1 - 0.052 13.6 1.0 0.17 12.0 0.1 2.1 2 1 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) zf-GRF PF06839.7 KRH91733.1 - 1.9e-13 50.0 12.2 2.5e-12 46.5 3.2 2.1 2 0 0 2 2 2 2 GRF zinc finger Jiv90 PF14901.1 KRH91733.1 - 0.075 13.0 0.6 0.084 12.8 0.4 1.1 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Zn_ribbon_recom PF13408.1 KRH91733.1 - 0.26 11.5 5.0 0.39 11.0 3.5 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain eIF3g PF12353.3 KRH91734.1 - 5e-05 23.2 2.6 8.7e-05 22.4 1.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 KRH91734.1 - 0.00018 21.2 0.2 0.00039 20.2 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Thg1C PF14413.1 KRH91734.1 - 0.024 14.3 0.4 0.031 13.9 0.3 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain DUF1574 PF07611.6 KRH91734.1 - 0.024 13.5 0.2 0.027 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) zf-CCHC_2 PF13696.1 KRH91734.1 - 0.1 12.1 0.2 0.51 9.8 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF4208 PF13907.1 KRH91734.1 - 0.15 12.2 1.7 0.23 11.6 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) ATP_bind_1 PF03029.12 KRH91735.1 - 1.8e-28 99.6 0.2 8e-28 97.5 0.1 1.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KRH91735.1 - 0.0053 16.6 0.6 0.01 15.7 0.4 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KRH91735.1 - 0.017 15.9 0.0 0.021 15.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KRH91735.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KRH91735.1 - 0.032 14.0 0.0 0.042 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KRH91735.1 - 0.034 13.3 0.1 0.17 11.0 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KRH91735.1 - 0.11 12.7 0.4 0.44 10.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain CbiA PF01656.18 KRH91735.1 - 0.12 11.7 0.4 0.37 10.1 0.3 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain WTF PF03303.8 KRH91735.1 - 0.18 11.1 1.7 0.28 10.5 1.2 1.2 1 0 0 1 1 1 0 WTF protein Carboxyl_trans PF01039.17 KRH91736.1 - 1.6e-14 53.1 0.0 1.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DUF658 PF04936.7 KRH91736.1 - 0.018 14.9 1.0 0.024 14.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) RPEL PF02755.10 KRH91736.1 - 0.96 8.8 5.2 3.8 6.9 0.3 3.2 1 1 2 3 3 3 0 RPEL repeat ER_lumen_recept PF00810.13 KRH91737.1 - 2.4e-08 34.5 1.4 2.4e-08 34.5 1.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KRH91737.1 - 0.0014 18.1 6.5 0.023 14.2 0.7 2.6 1 1 2 3 3 3 2 PQ loop repeat RVT_1 PF00078.22 KRH91739.1 - 5.9e-25 87.8 0.3 7.3e-25 87.5 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH91740.1 - 1.5e-25 89.7 0.3 1.9e-25 89.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.26 KRH91741.1 - 6.4e-05 22.7 0.1 0.0013 18.5 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Peptidase_M85 PF13678.1 KRH91741.1 - 0.001 18.5 1.1 0.0045 16.3 0.0 1.9 1 1 1 2 2 2 1 NFkB-p65-degrading zinc protease HSF_DNA-bind PF00447.12 KRH91742.1 - 3.9e-11 43.0 1.2 7.2e-11 42.1 0.6 1.7 1 1 0 1 1 1 1 HSF-type DNA-binding tRNA-synt_His PF13393.1 KRH91743.1 - 8.8e-16 57.8 0.0 1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KRH91743.1 - 2.7e-15 56.3 0.0 3.3e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 KRH91743.1 - 0.00054 19.2 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Spt4 PF06093.8 KRH91744.1 - 4.1e-09 36.1 0.2 6.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger rve PF00665.21 KRH91747.1 - 1.3e-09 38.2 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain TFIIS_C PF01096.13 KRH91748.1 - 2e-16 59.2 9.9 2e-16 59.2 6.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KRH91748.1 - 0.0017 17.9 3.9 0.0017 17.9 2.7 2.5 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit PHD PF00628.24 KRH91748.1 - 1.6 8.4 13.8 0.4 10.4 0.5 2.7 2 1 0 2 2 2 0 PHD-finger RPA_interact_C PF14768.1 KRH91748.1 - 2 8.9 15.8 4 7.9 11.0 1.6 1 1 0 1 1 1 0 Replication protein A interacting C-terminal AsnA PF03590.10 KRH91751.1 - 7.6e-39 133.5 0.8 8.8e-39 133.3 0.6 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 KRH91751.1 - 0.068 11.9 0.4 0.099 11.3 0.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) AsnA PF03590.10 KRH91752.1 - 2.1e-39 135.4 0.9 2.4e-39 135.2 0.6 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 KRH91752.1 - 0.093 11.4 0.4 0.13 10.9 0.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) TA0956 PF11513.3 KRH91752.1 - 0.11 12.5 1.0 0.18 11.8 0.3 1.6 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 rve PF00665.21 KRH91753.1 - 4.5e-08 33.2 0.1 8.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH91753.1 - 0.00058 19.3 0.1 0.002 17.5 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_1_2 PF13586.1 KRH91753.1 - 0.0052 16.9 0.7 0.0092 16.1 0.2 1.7 1 1 1 2 2 2 1 Transposase DDE domain rve PF00665.21 KRH91754.1 - 2.4e-07 30.8 0.1 4.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_1_2 PF13586.1 KRH91754.1 - 0.0029 17.7 0.4 0.0063 16.6 0.2 1.7 1 1 0 1 1 1 1 Transposase DDE domain rve_3 PF13683.1 KRH91754.1 - 0.0057 16.1 0.1 0.015 14.8 0.0 1.8 1 1 1 2 2 2 1 Integrase core domain BOF PF04076.8 KRH91754.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein GCS PF03074.11 KRH91755.1 - 1.3e-26 93.5 2.5 1.5e-26 93.3 1.7 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase LicD PF04991.8 KRH91756.1 - 0.34 10.9 11.2 0.15 12.1 6.1 1.6 1 1 0 1 1 1 0 LicD family RVT_1 PF00078.22 KRH91757.1 - 6e-13 48.6 0.1 8.8e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TAN PF11640.3 KRH91757.1 - 0.03 14.0 0.7 0.04 13.6 0.5 1.1 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Med3 PF11593.3 KRH91757.1 - 8.8 5.4 7.2 0.89 8.7 1.9 1.5 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal SLS PF14611.1 KRH91758.1 - 0.014 14.8 3.3 0.019 14.4 2.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator SCAN PF02023.12 KRH91758.1 - 0.034 13.6 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 SCAN domain SCAN PF02023.12 KRH91759.1 - 0.052 13.0 0.1 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 SCAN domain RNA_pol_Rpb2_1 PF04563.10 KRH91760.1 - 1.2e-07 30.8 0.3 1.4e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KRH91760.1 - 8.7e-05 22.0 2.8 0.00012 21.5 1.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RVT_1 PF00078.22 KRH91761.1 - 3e-20 72.5 0.9 4.6e-20 71.8 0.6 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G PF03179.10 KRH91762.1 - 0.00016 21.8 7.8 0.00027 21.2 5.2 1.5 1 1 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YrzO PF14142.1 KRH91762.1 - 0.022 14.3 0.4 0.022 14.3 0.3 1.8 2 0 0 2 2 2 0 YrzO-like protein MTBP_mid PF14919.1 KRH91762.1 - 0.043 12.5 0.7 0.045 12.4 0.5 1.2 1 0 0 1 1 1 0 MDM2-binding Penicillinase_R PF03965.11 KRH91762.1 - 0.048 13.7 1.8 0.069 13.2 1.3 1.2 1 0 0 1 1 1 0 Penicillinase repressor DUF2870 PF11069.3 KRH91762.1 - 0.18 11.8 3.0 0.27 11.2 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Fe_hyd_SSU PF02256.12 KRH91763.1 - 0.11 12.5 0.5 1.7 8.7 0.0 2.0 1 1 1 2 2 2 0 Iron hydrogenase small subunit Peptidase_M16 PF00675.15 KRH91764.1 - 2.1e-07 30.7 0.0 2.3e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16 PF00675.15 KRH91765.1 - 7.5e-23 80.9 0.0 9.5e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-C4_Topoisom PF01396.14 KRH91766.1 - 0.0086 15.5 2.3 0.013 14.9 1.6 1.4 1 1 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Elf1 PF05129.8 KRH91766.1 - 0.018 14.6 0.8 0.019 14.6 0.6 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PapB PF03333.8 KRH91766.1 - 0.022 14.5 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein zf-ribbon_3 PF13248.1 KRH91766.1 - 0.035 13.2 0.1 0.065 12.4 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 KRH91766.1 - 0.051 12.9 1.3 0.049 12.9 0.9 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn-ribbon_8 PF09723.5 KRH91766.1 - 0.063 13.2 1.9 0.081 12.8 0.1 1.9 2 0 0 2 2 2 0 Zinc ribbon domain SOCS PF12610.3 KRH91766.1 - 0.065 13.5 0.7 0.1 12.9 0.3 1.5 1 1 1 2 2 2 0 Suppressor of cytokine signalling T4_baseplate PF12322.3 KRH91766.1 - 0.11 11.7 0.4 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zinc_ribbon_2 PF13240.1 KRH91766.1 - 0.18 11.3 1.2 0.31 10.5 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 KRH91766.1 - 0.37 10.5 5.4 2.5 7.8 3.8 2.0 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF4274 PF14096.1 KRH91769.1 - 0.041 13.6 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DUF1235 PF06822.7 KRH91770.1 - 0.023 13.6 1.1 0.036 13.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) DUF1235 PF06822.7 KRH91771.1 - 0.018 13.9 1.4 0.029 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) RVT_1 PF00078.22 KRH91772.1 - 3.3e-18 65.8 0.3 5.2e-18 65.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH91773.1 - 8.7e-27 93.8 0.1 1.2e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CutC PF03932.9 KRH91774.1 - 0.0068 15.6 0.0 0.0099 15.1 0.0 1.2 1 0 0 1 1 1 1 CutC family Retrotrans_gag PF03732.12 KRH91774.1 - 0.05 13.6 0.3 0.28 11.2 0.0 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein Methyltransf_31 PF13847.1 KRH91776.1 - 0.0011 18.6 0.9 0.0018 17.9 0.6 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KRH91776.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KRH91776.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Flavodoxin_1 PF00258.20 KRH91777.1 - 5.6e-21 75.0 0.0 7.1e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin DUF3634 PF12321.3 KRH91777.1 - 0.0023 17.8 0.1 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3634) Flavodoxin_5 PF12724.2 KRH91777.1 - 0.015 15.3 0.0 0.14 12.1 0.0 2.0 1 1 1 2 2 2 0 Flavodoxin domain LRR_8 PF13855.1 KRH91778.1 - 1.3e-20 72.9 65.9 6.2e-09 35.4 3.5 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KRH91778.1 - 3e-20 71.3 48.0 1e-08 34.6 6.7 4.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KRH91778.1 - 1.2e-11 42.9 30.3 0.0047 16.7 0.3 7.4 7 1 0 7 7 7 6 Leucine Rich Repeat LRR_7 PF13504.1 KRH91778.1 - 2.1e-10 39.0 24.6 0.046 13.9 0.2 8.0 8 0 0 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 KRH91778.1 - 6.6e-08 31.8 30.0 0.042 13.9 0.1 7.0 6 1 0 6 6 6 4 Leucine Rich repeat HC2 PF07382.6 KRH91779.1 - 0.1 12.4 37.2 0.13 12.1 25.8 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 BCD PF15461.1 KRH91780.1 - 0.024 14.0 1.8 0.027 13.8 1.2 1.0 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF1700 PF08006.6 KRH91780.1 - 0.048 12.9 2.9 0.057 12.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4181 PF13789.1 KRH91780.1 - 0.48 10.3 8.2 0.59 10.0 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) TAFII28 PF04719.9 KRH91781.1 - 2.2e-26 91.4 0.0 3.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region FbpA PF05833.6 KRH91781.1 - 0.045 12.3 5.4 0.89 8.0 0.0 2.2 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) RRN3 PF05327.6 KRH91781.1 - 6.1 4.8 8.3 0.73 7.8 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 V_cholerae_RfbT PF05575.6 KRH91782.1 - 0.00017 20.7 1.0 0.0002 20.5 0.7 1.0 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein rve PF00665.21 KRH91783.1 - 8.2e-23 80.7 0.1 1.1e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KRH91783.1 - 0.0022 17.6 4.1 0.0032 17.0 2.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 KRH91783.1 - 0.015 14.8 0.2 0.046 13.2 0.0 1.9 3 0 0 3 3 3 0 Integrase core domain Ribosomal_L31e PF01198.14 KRH91784.1 - 3.6e-16 58.5 1.6 4.4e-16 58.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_S30 PF04758.9 KRH91785.1 - 3.2e-16 58.8 4.3 4e-16 58.4 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 ER_lumen_recept PF00810.13 KRH91786.1 - 2.4e-08 34.5 1.4 2.4e-08 34.5 1.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KRH91786.1 - 0.0014 18.1 6.5 0.023 14.2 0.7 2.6 1 1 2 3 3 3 2 PQ loop repeat Tim17 PF02466.14 KRH91787.1 - 4.1e-10 39.7 2.6 9.8e-10 38.5 1.8 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2040 PF09745.4 KRH91788.1 - 0.0047 16.7 2.5 0.0059 16.4 1.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF4435 PF14491.1 KRH91788.1 - 0.017 14.9 3.5 0.014 15.2 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) DUF89 PF01937.14 KRH91788.1 - 0.081 11.6 2.1 2 7.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF89 PYST-C1 PF09690.5 KRH91788.1 - 2.7 7.6 11.9 0.54 9.9 0.2 2.8 3 0 0 3 3 3 0 Plasmodium yoelii subtelomeric region (PYST-C1) Swi5 PF07061.6 KRH91789.1 - 3.1e-16 58.9 1.2 3.1e-16 58.9 0.8 1.6 2 0 0 2 2 2 1 Swi5 Tn7_Tnp_TnsA_C PF08721.6 KRH91789.1 - 0.034 14.1 0.7 0.071 13.1 0.5 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal Sec1 PF00995.18 KRH91789.1 - 0.052 12.1 4.5 0.059 11.9 3.1 1.0 1 0 0 1 1 1 0 Sec1 family HmuY PF14064.1 KRH91789.1 - 0.06 13.3 0.4 0.07 13.1 0.3 1.2 1 0 0 1 1 1 0 HmuY protein Kinesin PF00225.18 KRH91790.1 - 7.5e-28 97.1 0.1 7.5e-28 97.1 0.1 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF1319 PF07028.6 KRH91790.1 - 0.002 18.3 0.0 0.008 16.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1319) DUF972 PF06156.8 KRH91790.1 - 0.74 10.1 6.1 0.85 9.9 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DDE_Tnp_IS1595 PF12762.2 KRH91791.1 - 2.7e-16 59.7 0.1 2.9e-16 59.6 0.1 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.1 KRH91791.1 - 0.012 15.5 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 DDE domain Na_H_Exchanger PF00999.16 KRH91792.1 - 1e-05 24.2 2.0 1.2e-05 24.0 1.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Potyvirid-P3 PF13608.1 KRH91792.1 - 0.0081 15.3 0.2 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein PUF PF00806.14 KRH91796.1 - 0.00088 18.6 0.5 0.034 13.6 0.1 3.3 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat DUF1987 PF09345.5 KRH91796.1 - 0.043 13.6 2.1 0.06 13.1 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1987) Utp13 PF08625.6 KRH91796.1 - 0.14 11.7 3.1 5 6.7 0.1 2.1 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain RINGv PF12906.2 KRH91797.1 - 2.1e-10 40.4 9.3 4.1e-10 39.5 6.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KRH91797.1 - 1.2 8.9 13.8 8.4 6.3 5.4 2.6 2 1 0 2 2 2 0 Ring finger domain Cytochrom_B562 PF07361.6 KRH91798.1 - 0.64 10.4 3.8 0.76 10.2 0.4 2.5 2 1 1 3 3 3 0 Cytochrome b562 zf-C4H2 PF10146.4 KRH91798.1 - 0.64 9.9 7.1 0.13 12.2 1.0 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Ribosomal_L7Ae PF01248.21 KRH91799.1 - 1.5e-16 59.7 0.0 1.7e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CSD PF00313.17 KRH91800.1 - 0.029 14.1 0.6 0.079 12.7 0.4 1.7 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain ASCH PF04266.9 KRH91802.1 - 0.015 15.7 1.1 1.2 9.5 0.2 2.1 1 1 1 2 2 2 0 ASCH domain Imm6 PF14434.1 KRH91802.1 - 0.051 13.2 0.7 0.065 12.9 0.5 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 Rabaptin PF03528.10 KRH91802.1 - 0.054 13.4 3.2 0.17 11.8 2.2 1.7 1 1 0 1 1 1 0 Rabaptin CHCH PF06747.8 KRH91802.1 - 0.056 13.3 2.2 0.71 9.8 0.3 2.3 2 0 0 2 2 2 0 CHCH domain DUF1366 PF07104.6 KRH91802.1 - 0.12 11.9 2.5 0.17 11.4 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) DUF1456 PF07308.8 KRH91802.1 - 0.16 12.0 2.3 4.8 7.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) Pox_A3L PF05288.6 KRH91802.1 - 0.17 11.6 1.5 11 5.8 0.1 2.3 1 1 1 2 2 2 0 Poxvirus A3L Protein DUF4315 PF14193.1 KRH91802.1 - 0.33 10.9 4.7 0.37 10.7 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) CaMKII_AD PF08332.5 KRH91804.1 - 0.055 13.3 0.3 0.12 12.2 0.2 1.6 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DUF1456 PF07308.8 KRH91804.1 - 0.64 10.0 3.6 9 6.4 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1456) DUF3157 PF11355.3 KRH91805.1 - 0.071 12.3 0.0 0.071 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Herpes_U15 PF05613.6 KRH91806.1 - 0.16 12.3 3.2 0.15 12.4 1.9 1.2 1 1 0 1 1 1 0 Human herpesvirus U15 protein RNA_pol_Rpb2_6 PF00562.23 KRH91809.1 - 1.4e-07 30.5 0.2 1.6e-07 30.4 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Sec3_C_2 PF15278.1 KRH91809.1 - 0.0013 18.8 3.6 0.33 11.1 0.1 2.5 1 1 1 2 2 2 2 Sec3 exocyst complex subunit Exonuc_VII_L PF02601.10 KRH91809.1 - 0.0033 16.6 7.3 0.004 16.4 5.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit KapB PF08810.5 KRH91809.1 - 0.0056 16.7 0.8 1.1 9.2 0.0 2.5 1 1 1 2 2 2 1 Kinase associated protein B ISG65-75 PF11727.3 KRH91809.1 - 0.021 13.8 6.1 0.026 13.5 4.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF4164 PF13747.1 KRH91809.1 - 0.028 14.5 1.1 0.088 12.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Activator-TraM PF11657.3 KRH91809.1 - 0.062 12.7 0.3 9.6 5.6 0.1 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM Cementoin PF10511.4 KRH91809.1 - 0.63 9.8 6.7 29 4.6 0.0 5.8 5 2 1 6 6 6 0 Trappin protein transglutaminase binding domain PRKCSH-like PF12999.2 KRH91809.1 - 0.7 9.4 5.7 0.68 9.4 1.9 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like Prefoldin_2 PF01920.15 KRH91809.1 - 0.75 9.5 6.8 1.3 8.8 1.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.4 KRH91809.1 - 0.82 9.6 6.0 0.4 10.6 1.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KLRAQ PF10205.4 KRH91809.1 - 1.1 9.2 8.8 1.3 9.0 3.3 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Cortex-I_coil PF09304.5 KRH91809.1 - 1.5 8.8 12.2 2.1 8.4 5.6 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Fib_alpha PF08702.5 KRH91809.1 - 2.2 8.4 6.2 20 5.3 4.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LURAP PF14854.1 KRH91809.1 - 3.2 7.4 12.2 10 5.8 2.7 2.6 1 1 1 2 2 2 0 Leucine rich adaptor protein MbeB_N PF04837.7 KRH91809.1 - 6.7 6.8 8.9 1.9 8.6 0.1 2.9 2 1 1 3 3 3 0 MbeB-like, N-term conserved region AMP-binding PF00501.23 KRH91811.1 - 5.2e-20 71.2 1.5 2e-18 66.0 1.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme DDE_3 PF13358.1 KRH91812.1 - 0.0025 17.5 0.0 0.0028 17.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KRH91813.1 - 5.5e-17 61.8 0.0 6.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 KRH91814.1 - 2.3e-20 72.8 0.0 2.7e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH91814.1 - 6.9e-08 31.8 0.0 1.4e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DDE_3 PF13358.1 KRH91815.1 - 4.7e-28 97.7 0.0 5.6e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 KRH91815.1 - 0.0023 17.0 0.1 0.003 16.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease XFP PF03894.10 KRH91815.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase LNS2 PF08235.8 KRH91816.1 - 2.1e-09 37.1 0.1 4.1e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) V_ATPase_I PF01496.14 KRH91817.1 - 2.6e-08 32.2 1.2 3.2e-08 31.9 0.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LytTR PF04397.10 KRH91817.1 - 0.0091 16.0 0.2 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 LytTr DNA-binding domain Virulence_RhuM PF13310.1 KRH91817.1 - 0.016 14.2 1.2 0.026 13.5 0.7 1.5 1 1 0 1 1 1 0 Virulence protein RhuM family DUF929 PF06053.6 KRH91817.1 - 0.022 13.8 0.4 0.035 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) CAMP_factor PF07373.6 KRH91817.1 - 0.029 13.8 0.4 0.054 12.9 0.3 1.4 1 1 0 1 1 1 0 CAMP factor (Cfa) ACCA PF03255.9 KRH91817.1 - 0.11 12.0 1.6 0.16 11.4 1.1 1.4 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit XhlA PF10779.4 KRH91817.1 - 8.5 6.3 9.4 1.9 8.4 2.3 2.4 2 1 0 2 2 2 0 Haemolysin XhlA TAF8_C PF10406.4 KRH91818.1 - 7.4e-10 38.7 0.2 7.4e-10 38.7 0.2 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Daxx PF03344.10 KRH91818.1 - 0.048 12.1 12.6 0.052 12.0 8.7 1.1 1 0 0 1 1 1 0 Daxx Family FAM131 PF15010.1 KRH91818.1 - 0.078 12.7 4.1 0.085 12.5 2.8 1.1 1 0 0 1 1 1 0 Putative cell signalling DUF4041 PF13250.1 KRH91818.1 - 0.081 12.4 0.7 0.95 9.0 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4041) Ycf1 PF05758.7 KRH91818.1 - 0.085 10.5 12.3 0.092 10.4 8.5 1.1 1 0 0 1 1 1 0 Ycf1 SMC_Nse1 PF07574.8 KRH91818.1 - 0.086 12.4 8.4 0.13 11.8 5.9 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Lipocalin_2 PF08212.7 KRH91818.1 - 0.12 12.2 1.9 0.15 11.8 1.3 1.2 1 0 0 1 1 1 0 Lipocalin-like domain Exonuc_VII_L PF02601.10 KRH91818.1 - 0.29 10.2 8.0 0.38 9.9 5.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.9 KRH91818.1 - 0.78 7.7 11.7 0.87 7.5 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.1 KRH91818.1 - 1.3 8.2 8.3 1.4 8.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Paramyxo_ncap PF00973.14 KRH91818.1 - 1.4 7.5 7.9 1.8 7.2 5.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CKAP2_C PF15297.1 KRH91818.1 - 2.8 6.6 15.2 0.8 8.4 8.6 1.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Nop53 PF07767.6 KRH91818.1 - 3.1 6.6 20.0 5.5 5.8 13.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Astro_capsid PF03115.9 KRH91818.1 - 3.4 5.7 7.6 3.8 5.6 5.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor UN_NPL4 PF11543.3 KRH91818.1 - 4 7.8 6.7 4.6 7.5 0.1 2.6 2 1 1 3 3 3 0 Nuclear pore localisation protein NPL4 Lumazine_bd PF12870.2 KRH91818.1 - 5.9 6.9 14.9 1.9 8.5 8.1 1.7 2 0 0 2 2 2 0 Lumazine-binding domain Membralin PF09746.4 KRH91818.1 - 6.9 5.6 7.8 10 5.0 5.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.11 KRH91818.1 - 9.5 6.0 8.1 13 5.6 5.6 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region rve PF00665.21 KRH91819.1 - 8.2e-16 58.1 0.0 9.4e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH91819.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 KRH91820.1 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain zf-XS PF03470.9 KRH91822.1 - 0.2 11.7 0.9 0.37 10.8 0.6 1.5 1 0 0 1 1 1 0 XS zinc finger domain DDE_3 PF13358.1 KRH91823.1 - 6e-16 58.4 0.0 7.1e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 KRH91823.1 - 8.2e-05 22.6 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 KRH91825.1 - 8.3e-15 54.9 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain zf-XS PF03470.9 KRH91825.1 - 0.056 13.4 0.3 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 XS zinc finger domain RdRP PF05183.7 KRH91826.1 - 8.1e-37 127.1 0.1 9.3e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DNA_gyraseB PF00204.20 KRH91827.1 - 1.5e-12 47.0 0.3 3.7e-12 45.8 0.1 1.7 2 0 0 2 2 2 1 DNA gyrase B rve PF00665.21 KRH91828.1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain GCS PF03074.11 KRH91830.1 - 7.7e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase MRP-L28 PF09812.4 KRH91830.1 - 0.076 12.8 0.8 0.1 12.3 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 zinc-ribbons_6 PF07191.7 KRH91831.1 - 0.083 12.6 9.0 0.76 9.6 0.7 3.0 2 2 0 2 2 2 0 zinc-ribbons ResB PF05140.9 KRH91831.1 - 0.087 11.3 1.0 5 5.5 0.1 2.3 1 1 1 2 2 2 0 ResB-like family Thioredoxin_5 PF13743.1 KRH91831.1 - 9.3 5.7 20.5 10 5.6 1.3 3.9 1 1 3 4 4 4 0 Thioredoxin zf-Nse PF11789.3 KRH91832.1 - 4.8e-12 45.2 1.3 8.9e-12 44.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KRH91832.1 - 0.0094 15.7 1.5 0.017 14.9 1.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KRH91832.1 - 0.035 13.8 2.4 0.079 12.6 0.6 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KRH91832.1 - 0.21 11.6 3.2 0.48 10.5 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH91832.1 - 0.31 10.7 2.2 0.71 9.5 1.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.22 KRH91834.1 - 5.5e-12 45.5 0.0 6.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH91834.1 - 0.056 12.4 0.1 0.062 12.2 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Osmo_CC PF08946.5 KRH91834.1 - 0.13 12.3 3.0 0.21 11.6 2.1 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil EFG_C PF00679.19 KRH91835.1 - 0.002 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus WD40 PF00400.27 KRH91836.1 - 2.8e-12 46.0 0.0 4.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Rrn6 PF10214.4 KRH91836.1 - 0.014 13.5 0.6 0.047 11.7 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor GRAM PF02893.15 KRH91837.1 - 0.0062 16.0 0.2 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 KRH91837.1 - 0.012 15.3 1.8 0.014 15.2 0.0 2.1 2 1 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 RVT_1 PF00078.22 KRH91838.1 - 2.7e-22 79.1 0.1 4e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH91840.1 - 2.1e-09 36.8 10.3 1.1e-05 25.1 1.1 5.9 6 0 0 6 6 6 2 Zinc knuckle zf-CCHC_4 PF14392.1 KRH91840.1 - 0.026 14.1 1.7 0.026 14.1 1.2 5.0 3 1 2 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.1 KRH91840.1 - 0.038 13.4 21.6 1 8.8 0.1 4.6 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.1 KRH91840.1 - 9 5.8 28.8 0.41 10.1 3.3 4.2 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger rve PF00665.21 KRH91841.1 - 2.5e-11 43.7 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH91841.1 - 0.065 12.7 0.1 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain RNA_pol_Rpb2_6 PF00562.23 KRH91843.1 - 3.7e-23 81.8 0.3 4.3e-23 81.6 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 KRH91843.1 - 3.4e-18 65.6 0.1 6.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 MAD PF05557.8 KRH91844.1 - 5.2e-11 41.3 13.1 1.4e-10 39.9 9.1 1.8 1 1 0 1 1 1 1 Mitotic checkpoint protein Microtub_assoc PF07989.6 KRH91844.1 - 0.00058 19.6 12.7 0.00093 18.9 8.5 1.6 1 1 0 1 1 1 1 Microtubule associated V_ATPase_I PF01496.14 KRH91844.1 - 0.0038 15.1 5.5 0.0039 15.1 3.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GET2 PF08690.5 KRH91844.1 - 0.0087 15.3 0.5 0.011 15.0 0.4 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 HALZ PF02183.13 KRH91844.1 - 0.0096 15.6 1.1 0.027 14.1 0.8 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper Peptidase_M30 PF10460.4 KRH91844.1 - 0.039 12.8 0.1 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 DUF3598 PF12204.3 KRH91844.1 - 0.062 12.5 0.7 0.081 12.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) IFP_35_N PF07334.8 KRH91844.1 - 0.12 12.3 5.9 0.12 12.3 3.2 1.7 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YlqD PF11068.3 KRH91844.1 - 0.24 11.4 8.4 0.31 11.0 5.8 1.2 1 0 0 1 1 1 0 YlqD protein DUF1395 PF07160.7 KRH91844.1 - 0.5 9.8 7.5 1.7 8.1 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) GerA PF03323.8 KRH91844.1 - 0.68 7.9 4.4 0.92 7.5 3.1 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DivIVA PF05103.8 KRH91844.1 - 0.75 9.8 11.5 7.1 6.6 7.9 2.1 1 1 0 1 1 1 0 DivIVA protein Snapin_Pallidin PF14712.1 KRH91844.1 - 1.6 9.0 9.6 2.3 8.5 0.4 2.5 1 1 1 2 2 2 0 Snapin/Pallidin DUF972 PF06156.8 KRH91844.1 - 1.8 8.9 11.6 1.4 9.2 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RVT_1 PF00078.22 KRH91845.1 - 2.5e-07 30.2 0.0 3.3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abi_HHR PF07815.9 KRH91845.1 - 0.035 14.2 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Abl-interactor HHR MHC_I PF00129.13 KRH91845.1 - 0.089 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 RVT_1 PF00078.22 KRH91846.1 - 1.5e-07 30.9 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Abi_HHR PF07815.9 KRH91846.1 - 0.025 14.6 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Abl-interactor HHR RVT_1 PF00078.22 KRH91848.1 - 1.4e-17 63.7 0.2 1.6e-17 63.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Curlin_rpt PF07012.7 KRH91848.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Curlin associated repeat FAINT PF04385.10 KRH91848.1 - 0.064 13.1 0.4 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 gag_pre-integrs PF13976.1 KRH91849.1 - 0.00028 20.4 0.9 0.00054 19.5 0.6 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KRH91849.1 - 0.0053 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain LacY_symp PF01306.14 KRH91850.1 - 0.0059 15.2 8.2 0.0082 14.7 5.7 1.2 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1 PF07690.11 KRH91850.1 - 0.023 13.4 8.8 0.01 14.5 4.5 1.6 1 1 0 2 2 2 0 Major Facilitator Superfamily rve PF00665.21 KRH91851.1 - 1.4e-15 57.4 0.9 1.8e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH91851.1 - 0.0053 16.2 0.6 0.046 13.2 0.0 2.7 2 1 1 3 3 3 1 Integrase core domain Ufm1 PF03671.9 KRH91851.1 - 0.085 12.6 0.0 0.48 10.2 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin fold modifier 1 protein RVP PF00077.15 KRH91852.1 - 2e-07 30.8 0.7 5.4e-07 29.4 0.1 1.8 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH91852.1 - 0.00017 22.0 0.1 0.00062 20.2 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH91852.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RNase_P_Rpp14 PF01900.14 KRH91853.1 - 4.3e-09 36.2 0.2 5e-09 36.0 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SNF2_N PF00176.18 KRH91854.1 - 7e-18 64.4 0.2 8.9e-18 64.1 0.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KRH91854.1 - 0.004 16.9 0.8 0.0099 15.7 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KRH91854.1 - 0.039 12.9 0.5 0.26 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 KRH91854.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PRANC PF09372.5 KRH91854.1 - 0.12 12.3 3.8 0.11 12.4 1.0 2.2 2 0 0 2 2 2 0 PRANC domain NinE PF05322.6 KRH91854.1 - 0.21 11.3 1.3 0.43 10.3 0.1 2.1 3 0 0 3 3 3 0 NINE Protein CRISPR_assoc PF08798.6 KRH91856.1 - 0.32 10.7 0.1 0.32 10.7 0.1 1.9 3 0 0 3 3 3 0 CRISPR associated protein CDtoxinA PF03498.9 KRH91857.1 - 0.0018 17.6 0.1 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 KRH91857.1 - 0.0031 17.8 0.0 0.0076 16.6 0.0 1.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KRH91857.1 - 0.027 14.4 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain HTH_Tnp_Tc3_2 PF01498.13 KRH91858.1 - 1.3e-10 41.1 0.1 1.3e-10 41.1 0.1 1.5 2 0 0 2 2 2 1 Transposase HTH_21 PF13276.1 KRH91858.1 - 0.0052 16.7 0.4 0.0077 16.2 0.2 1.3 1 0 0 1 1 1 1 HTH-like domain HTH_33 PF13592.1 KRH91858.1 - 0.022 14.3 0.5 0.043 13.3 0.0 1.8 2 1 0 2 2 2 0 Winged helix-turn helix Arg_repressor PF01316.16 KRH91858.1 - 0.045 13.2 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain HTH_29 PF13551.1 KRH91858.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.1 KRH91858.1 - 0.12 13.2 0.0 0.22 12.3 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 KRH91859.1 - 0.0074 16.0 0.1 0.0078 15.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-BED PF02892.10 KRH91859.1 - 0.15 11.8 0.8 0.26 11.0 0.5 1.4 1 0 0 1 1 1 0 BED zinc finger Nop PF01798.13 KRH91862.1 - 6.4e-21 74.2 0.1 1.2e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain RVT_1 PF00078.22 KRH91863.1 - 3.6e-21 75.5 0.6 5.2e-21 74.9 0.4 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RepL PF05732.6 KRH91863.1 - 0.24 10.5 1.3 0.34 10.1 0.9 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) RVT_1 PF00078.22 KRH91864.1 - 8.2e-19 67.8 0.1 1e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2024 PF09630.5 KRH91864.1 - 0.14 11.9 0.4 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) DUF2346 PF09803.4 KRH91865.1 - 4 7.3 19.3 27 4.6 0.5 5.7 3 1 3 6 6 6 0 Uncharacterized conserved protein (DUF2346) TRM PF02005.11 KRH91866.1 - 1.3e-27 96.6 0.1 1.9e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_16 PF10294.4 KRH91866.1 - 9.6e-05 21.9 0.1 0.00021 20.7 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KRH91866.1 - 0.036 13.6 0.4 0.062 12.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 KRH91866.1 - 0.13 11.8 1.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Met-10+ like-protein UCH PF00443.24 KRH91867.1 - 6.6e-10 38.5 0.5 9e-10 38.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH91867.1 - 7.1e-05 22.3 0.2 9.1e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DDE_Tnp_IS1595 PF12762.2 KRH91868.1 - 1.2e-12 47.8 0.1 1.5e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF962 PF06127.6 KRH91869.1 - 0.0058 16.5 0.0 0.037 13.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF962) PAP_central PF04928.12 KRH91870.1 - 4.1e-71 238.7 0.1 4.6e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain RVT_1 PF00078.22 KRH91872.1 - 0.018 14.4 0.0 0.019 14.3 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.24 KRH91874.1 - 6.8e-11 41.7 1.5 1.5e-10 40.6 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH91874.1 - 0.00049 19.6 0.7 0.00081 18.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KRH91875.1 - 2.8e-12 46.0 0.0 4.4e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Rrn6 PF10214.4 KRH91875.1 - 0.014 13.5 0.6 0.047 11.7 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DUF663 PF04950.7 KRH91876.1 - 1e-10 41.0 0.3 1e-10 41.0 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF663) MAGE PF01454.14 KRH91876.1 - 0.01 15.2 0.5 0.012 14.9 0.4 1.2 1 0 0 1 1 1 0 MAGE family DDE_Tnp_IS1595 PF12762.2 KRH91877.1 - 1.2e-28 99.8 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH91877.1 - 0.1 12.0 2.3 0.38 10.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Ribosomal_L3 PF00297.17 KRH91878.1 - 1.2e-06 28.1 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF59 PF01883.14 KRH91879.1 - 0.0084 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 DnaJ PF00226.26 KRH91880.1 - 0.034 13.8 0.4 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain CcmH PF03918.9 KRH91880.1 - 0.045 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein 7TM_GPCR_Srv PF10323.4 KRH91880.1 - 0.071 12.2 2.1 0.04 13.0 0.3 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM154 PF15102.1 KRH91880.1 - 0.11 12.2 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family CCSMST1 PF15013.1 KRH91880.1 - 0.16 11.9 0.9 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 CCSMST1 family DUF4446 PF14584.1 KRH91880.1 - 0.28 11.0 3.4 0.53 10.1 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) ATP-synt_8 PF00895.15 KRH91880.1 - 3.8 7.7 8.4 0.35 11.0 0.4 2.8 3 0 0 3 3 3 0 ATP synthase protein 8 rve PF00665.21 KRH91881.1 - 2.3e-06 27.7 0.0 2.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L3 PF00297.17 KRH91883.1 - 1.3e-48 165.7 0.3 1.5e-48 165.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 gag_pre-integrs PF13976.1 KRH91886.1 - 5.2e-07 29.2 0.1 1.1e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_3 PF13456.1 KRH91886.1 - 0.03 14.0 0.5 0.25 11.1 0.1 2.5 2 1 0 2 2 2 0 Reverse transcriptase-like T2SE PF00437.15 KRH91887.1 - 6e-06 25.3 0.1 6.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.10 KRH91887.1 - 3.3e-05 22.7 0.1 3.9e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KRH91887.1 - 0.00054 20.1 0.1 0.0011 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 KRH91887.1 - 0.0023 17.7 2.5 0.034 13.9 0.7 2.1 1 1 1 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KRH91887.1 - 0.0028 17.1 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.7 KRH91887.1 - 0.0042 16.2 0.1 0.01 14.9 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 KRH91887.1 - 0.0043 16.9 0.1 0.006 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KRH91887.1 - 0.0055 16.4 0.2 0.007 16.0 0.2 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KRH91887.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KRH91887.1 - 0.019 14.4 0.1 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KRH91887.1 - 0.026 13.1 0.0 0.03 12.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 KRH91887.1 - 0.03 13.8 0.1 0.06 12.8 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain GBP PF02263.14 KRH91887.1 - 0.03 13.3 0.5 0.094 11.7 0.4 1.8 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_17 PF13207.1 KRH91887.1 - 0.032 15.0 0.5 0.067 14.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KRH91887.1 - 0.032 13.7 0.2 0.095 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 KRH91887.1 - 0.038 12.9 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta2 PF13177.1 KRH91887.1 - 0.041 13.5 1.2 0.055 13.1 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF853 PF05872.7 KRH91887.1 - 0.052 11.8 0.1 0.076 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_29 PF13555.1 KRH91887.1 - 0.059 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Prominin PF05478.6 KRH91887.1 - 0.07 10.6 1.7 0.091 10.2 1.2 1.1 1 0 0 1 1 1 0 Prominin Sigma54_activ_2 PF14532.1 KRH91887.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KRH91887.1 - 0.11 11.8 0.7 0.4 10.0 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 KRH91887.1 - 0.14 12.4 2.8 0.31 11.3 2.1 1.4 1 1 0 1 1 1 0 AAA domain DUF552 PF04472.7 KRH91887.1 - 0.18 11.7 0.8 0.91 9.4 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF552) ABC_tran PF00005.22 KRH91887.1 - 0.18 12.0 1.9 0.63 10.3 1.3 1.8 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.10 KRH91887.1 - 0.31 10.8 2.1 0.73 9.6 1.4 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KRH91887.1 - 1.5 9.1 5.3 11 6.3 3.7 2.1 1 1 0 1 1 1 0 AAA domain RVP PF00077.15 KRH91888.1 - 6.6e-11 42.0 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH91888.1 - 2.8e-05 24.5 0.1 9.4e-05 22.8 0.0 2.0 3 0 0 3 3 3 1 Aspartyl protease RVP_2 PF08284.6 KRH91888.1 - 0.0047 16.8 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH91888.1 - 0.019 14.8 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 KRH91888.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Anticodon_1 PF08264.8 KRH91891.1 - 0.0018 18.0 3.5 0.004 16.9 2.0 1.9 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA Imm36 PF15597.1 KRH91891.1 - 0.081 13.0 2.6 0.25 11.5 1.8 1.8 1 1 0 1 1 1 0 Immunity protein 36 DNA_gyraseB PF00204.20 KRH91892.1 - 1.6e-12 47.0 0.2 6.3e-12 45.0 0.1 1.9 2 0 0 2 2 2 1 DNA gyrase B NosD PF05048.8 KRH91892.1 - 0.09 11.9 1.8 0.13 11.4 1.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Galanin PF01296.13 KRH91892.1 - 0.51 10.2 5.5 50 3.8 0.7 3.9 3 1 1 4 4 4 0 Galanin DUF2392 PF10288.4 KRH91894.1 - 0.0056 16.9 0.8 0.011 16.0 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) Phi_1 PF04674.7 KRH91894.1 - 0.12 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region DUF3767 PF12597.3 KRH91895.1 - 0.14 11.8 8.5 8.9 6.0 0.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3767) SNARE PF05739.14 KRH91898.1 - 0.003 17.2 1.5 0.003 17.2 1.0 1.9 2 0 0 2 2 2 1 SNARE domain TcdA_TcdB PF12919.2 KRH91898.1 - 0.033 12.6 15.2 0.046 12.1 10.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain AAA_14 PF13173.1 KRH91898.1 - 0.58 10.0 7.0 1.6 8.6 4.8 1.9 1 1 0 1 1 1 0 AAA domain 5_3_exonuc PF01367.15 KRH91898.1 - 6.5 7.0 8.9 0.34 11.1 0.8 2.5 1 1 2 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Sec20 PF03908.8 KRH91898.1 - 7.8 6.2 12.7 0.74 9.5 1.4 2.8 2 1 1 3 3 3 0 Sec20 Pkinase PF00069.20 KRH91899.1 - 7.2e-22 77.7 0.4 7.2e-22 77.7 0.3 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH91899.1 - 1.3e-12 47.3 0.1 2.1e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KRH91899.1 - 0.0029 16.4 0.6 0.004 16.0 0.4 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 KRH91899.1 - 0.0067 15.4 0.1 0.0085 15.0 0.1 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KRH91899.1 - 0.068 12.8 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L44 PF00935.14 KRH91900.1 - 6.6e-21 74.1 15.8 6.6e-21 74.1 10.9 1.4 1 1 1 2 2 2 1 Ribosomal protein L44 ProRS-C_1 PF09180.6 KRH91901.1 - 1.8e-19 69.4 1.3 2.6e-19 68.9 0.9 1.2 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal SMI1_KNR4 PF09346.5 KRH91901.1 - 0.098 12.6 0.2 0.21 11.5 0.1 1.8 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) rve PF00665.21 KRH91902.1 - 0.00058 19.9 0.0 0.00062 19.8 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Colicin_Pyocin PF01320.13 KRH91902.1 - 0.046 13.5 0.0 0.049 13.4 0.0 1.2 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein RVT_3 PF13456.1 KRH91903.1 - 0.008 15.9 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like DUF673 PF05054.7 KRH91905.1 - 0.057 11.9 1.7 0.061 11.8 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF673) IncA PF04156.9 KRH91907.1 - 7.7e-06 25.6 1.4 1.1e-05 25.1 1.0 1.1 1 0 0 1 1 1 1 IncA protein zf-RING_5 PF14634.1 KRH91907.1 - 8.9e-06 25.3 10.0 1.8e-05 24.3 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KRH91907.1 - 0.00046 19.9 4.8 0.00079 19.1 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KRH91907.1 - 0.0005 20.0 6.4 0.0012 18.8 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH91907.1 - 0.0066 16.0 12.3 0.087 12.5 8.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LicD PF04991.8 KRH91907.1 - 0.021 14.9 5.0 0.025 14.6 3.4 1.2 1 0 0 1 1 1 0 LicD family zf-C3HC4_4 PF15227.1 KRH91907.1 - 0.027 14.3 7.6 0.05 13.4 1.7 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING HALZ PF02183.13 KRH91907.1 - 0.04 13.6 2.2 0.096 12.4 1.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Gp-FAR-1 PF05823.7 KRH91907.1 - 0.048 13.6 4.0 0.088 12.7 2.8 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zf-ribbon_3 PF13248.1 KRH91907.1 - 0.064 12.4 0.9 0.13 11.5 0.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF904 PF06005.7 KRH91907.1 - 0.071 13.4 8.3 0.17 12.2 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) zf-RING_2 PF13639.1 KRH91907.1 - 0.11 12.3 6.2 0.27 11.1 4.3 1.8 1 1 0 1 1 1 0 Ring finger domain DUF1875 PF08961.5 KRH91907.1 - 0.12 11.7 2.0 0.17 11.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) zf-RING_UBOX PF13445.1 KRH91907.1 - 0.22 11.2 5.1 0.21 11.3 2.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger bZIP_1 PF00170.16 KRH91907.1 - 0.29 11.1 8.2 0.26 11.2 3.9 2.0 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 KRH91907.1 - 0.3 10.9 6.1 0.69 9.7 4.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Nup54 PF13874.1 KRH91907.1 - 0.41 10.3 4.3 0.59 9.7 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 zf-AN1 PF01428.11 KRH91907.1 - 4.2 7.3 8.3 0.49 10.3 1.1 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger DUF3959 PF13105.1 KRH91907.1 - 7.2 5.8 8.3 3.4 6.9 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3959) DUF508 PF04370.7 KRH91908.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) bZIP_1 PF00170.16 KRH91908.1 - 1.4 8.8 8.2 5.4 7.0 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor Geminin PF07412.7 KRH91908.1 - 5.1 6.7 11.9 0.46 10.1 2.6 2.0 1 1 1 2 2 2 0 Geminin DUF972 PF06156.8 KRH91908.1 - 6 7.2 10.5 0.33 11.3 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CH PF00307.26 KRH91910.1 - 4.8e-08 32.9 0.1 7.5e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KRH91910.1 - 0.028 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain CDC24 PF06395.6 KRH91910.1 - 0.12 12.4 0.5 0.42 10.7 0.1 1.9 2 0 0 2 2 2 0 CDC24 Calponin TAF4 PF05236.9 KRH91911.1 - 4.9e-09 35.8 3.9 3.3e-08 33.1 2.7 1.9 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID-18kDa PF02269.11 KRH91911.1 - 0.15 11.8 0.2 0.15 11.8 0.1 2.2 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit TFIIA_gamma_N PF02268.11 KRH91912.1 - 1.1e-13 50.5 0.3 1.6e-13 49.9 0.2 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KRH91912.1 - 0.0023 17.7 0.9 0.0048 16.6 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit DUF836 PF05768.9 KRH91912.1 - 0.016 15.4 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) PseudoU_synth_1 PF01416.15 KRH91913.1 - 6.4e-08 32.9 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridine synthase Dev_Cell_Death PF10539.4 KRH91913.1 - 0.074 12.6 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Development and cell death domain CTD PF12815.2 KRH91914.1 - 0.0098 16.3 13.1 0.016 15.6 8.7 1.7 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Apc9 PF12856.2 KRH91914.1 - 0.054 13.5 1.0 0.69 10.0 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 Axin_b-cat_bind PF08833.5 KRH91914.1 - 0.078 12.7 3.3 6.2 6.6 0.4 3.6 1 1 1 3 3 3 0 Axin beta-catenin binding domain CemA PF03040.9 KRH91915.1 - 0.016 14.8 3.4 0.021 14.4 2.4 1.1 1 0 0 1 1 1 0 CemA family Fes1 PF08609.5 KRH91915.1 - 0.039 14.4 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF1938 PF09153.5 KRH91915.1 - 0.13 12.0 3.5 3.2 7.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) RRM_1 PF00076.17 KRH91916.1 - 2e-30 104.1 4.3 2.8e-12 46.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH91916.1 - 3.9e-26 90.8 1.1 3.2e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH91916.1 - 4.1e-14 52.1 3.5 1.9e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KRH91916.1 - 4.3e-08 32.8 0.5 0.12 12.1 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KRH91916.1 - 0.0014 18.4 1.3 0.66 9.8 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif YafO_toxin PF13957.1 KRH91917.1 - 1.1 9.1 5.8 11 5.9 4.0 2.3 1 1 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system TF_Zn_Ribbon PF08271.7 KRH91918.1 - 7.3e-13 47.6 0.8 1.1e-12 47.0 0.6 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.12 KRH91918.1 - 0.0014 18.0 0.7 0.0025 17.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zf-ribbon_3 PF13248.1 KRH91918.1 - 0.004 16.3 0.5 0.45 9.8 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 KRH91918.1 - 0.0046 16.7 0.2 0.0095 15.7 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon GCC2_GCC3 PF07699.8 KRH91918.1 - 0.0046 16.4 0.3 0.0046 16.4 0.2 1.8 2 0 0 2 2 2 1 GCC2 and GCC3 zinc_ribbon_5 PF13719.1 KRH91918.1 - 0.012 15.1 0.5 0.023 14.2 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ArfGap PF01412.13 KRH91918.1 - 0.014 15.1 0.7 0.014 15.1 0.5 1.8 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_4 PF13717.1 KRH91918.1 - 0.019 14.6 0.5 0.035 13.7 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KRH91918.1 - 0.024 14.0 1.6 0.99 8.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Nha1_C PF08619.5 KRH91918.1 - 0.054 12.7 1.8 0.056 12.7 1.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2318 PF10080.4 KRH91918.1 - 0.11 12.3 1.6 0.18 11.5 0.5 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Lar_restr_allev PF14354.1 KRH91918.1 - 0.14 12.4 0.6 0.81 10.0 0.4 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar ABC2_membrane_3 PF12698.2 KRH91918.1 - 0.37 9.7 2.7 0.45 9.4 1.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ima1_N PF09779.4 KRH91918.1 - 1.3 9.4 9.8 3.7 8.0 6.7 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain SAP PF02037.22 KRH91920.1 - 3.5e-10 39.1 0.4 6.9e-10 38.1 0.2 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 KRH91920.1 - 0.00026 20.6 0.0 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain HeH PF12949.2 KRH91920.1 - 0.0024 17.3 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 2 HeH/LEM domain LETM1 PF07766.8 KRH91920.1 - 0.014 14.4 0.2 0.023 13.7 0.1 1.4 1 1 0 1 1 1 0 LETM1-like protein Helicase_C_3 PF13625.1 KRH91920.1 - 0.032 13.9 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 Helicase conserved C-terminal domain SCIMP PF15050.1 KRH91920.1 - 0.043 13.7 0.1 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 SCIMP protein WD40 PF00400.27 KRH91921.1 - 1.3e-11 43.9 3.9 0.0018 18.0 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KRH91921.1 - 0.00057 19.6 1.5 0.15 11.8 0.1 2.5 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region RHD3 PF05879.7 KRH91921.1 - 0.0089 14.0 0.0 0.013 13.4 0.0 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) HEAT_2 PF13646.1 KRH91923.1 - 4.9e-20 71.6 0.0 3.3e-09 36.9 0.0 2.2 1 1 2 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 KRH91923.1 - 0.002 18.4 0.0 0.67 10.5 0.0 3.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Methyltransf_31 PF13847.1 KRH91924.1 - 4.1e-12 45.9 0.4 6.1e-12 45.3 0.3 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KRH91924.1 - 1.8e-10 41.1 0.0 2.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KRH91924.1 - 4.4e-10 39.8 0.0 9.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KRH91924.1 - 3.3e-08 33.9 0.0 5.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KRH91924.1 - 5.5e-06 25.8 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 KRH91924.1 - 5.9e-06 26.8 0.0 9.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KRH91924.1 - 8.9e-06 25.5 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KRH91924.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KRH91924.1 - 7.9e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_N4_Mtase PF01555.13 KRH91924.1 - 0.00037 20.0 1.8 0.0059 16.1 0.1 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_32 PF13679.1 KRH91924.1 - 0.0031 17.2 0.1 0.0071 16.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KRH91924.1 - 0.006 15.6 0.2 0.011 14.8 0.1 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KRH91924.1 - 0.0089 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 KRH91924.1 - 0.013 14.5 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.13 KRH91924.1 - 0.02 14.2 0.1 0.073 12.3 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain PrmA PF06325.8 KRH91924.1 - 0.092 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RtcB PF01139.12 KRH91926.1 - 2.3e-26 92.7 23.0 2.7e-24 85.9 16.0 3.0 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB SprA-related PF12118.3 KRH91926.1 - 0.0043 16.4 20.9 0.0046 16.3 14.5 1.1 1 0 0 1 1 1 1 SprA-related family Pertus-S5-tox PF09276.5 KRH91926.1 - 0.0097 15.8 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 1 Pertussis toxin S5 subunit RR_TM4-6 PF06459.7 KRH91926.1 - 0.033 14.1 19.8 0.044 13.6 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Astro_capsid PF03115.9 KRH91926.1 - 0.07 11.3 11.6 0.082 11.1 8.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor AAA_23 PF13476.1 KRH91926.1 - 0.18 12.1 22.2 0.26 11.5 15.4 1.4 1 0 0 1 1 1 0 AAA domain Parvo_coat PF00740.13 KRH91926.1 - 1 8.2 13.0 1.1 8.0 9.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SOBP PF15279.1 KRH91926.1 - 1.8 8.9 10.3 2.2 8.6 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GAGA_bind PF06217.7 KRH91926.1 - 1.8 8.4 19.1 2.4 8.0 13.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Paf1 PF03985.8 KRH91926.1 - 2 7.0 26.0 3 6.4 18.0 1.3 1 0 0 1 1 1 0 Paf1 Asp-B-Hydro_N PF05279.6 KRH91926.1 - 3.3 7.5 22.9 4.5 7.0 15.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.11 KRH91926.1 - 3.7 6.0 14.5 5.1 5.5 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4613 PF15390.1 KRH91926.1 - 3.9 5.5 14.2 4.4 5.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2201_N PF13203.1 KRH91926.1 - 5.2 6.1 13.2 6.8 5.7 9.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SID-1_RNA_chan PF13965.1 KRH91926.1 - 8.2 4.4 8.4 9.2 4.2 5.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM91_C PF14648.1 KRH91926.1 - 9.2 4.9 15.7 13 4.5 10.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus TF_Zn_Ribbon PF08271.7 KRH91928.1 - 7.9e-13 47.5 0.8 1.2e-12 46.9 0.6 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.12 KRH91928.1 - 0.0015 18.0 0.7 0.0027 17.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 GCC2_GCC3 PF07699.8 KRH91928.1 - 0.0017 17.9 0.3 0.0051 16.3 0.2 1.7 1 0 0 1 1 1 1 GCC2 and GCC3 zf-ribbon_3 PF13248.1 KRH91928.1 - 0.0045 16.1 0.5 0.47 9.7 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 KRH91928.1 - 0.0052 16.5 0.2 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_5 PF13719.1 KRH91928.1 - 0.013 15.0 0.5 0.025 14.1 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ArfGap PF01412.13 KRH91928.1 - 0.014 15.1 0.6 0.014 15.1 0.4 1.8 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_4 PF13717.1 KRH91928.1 - 0.021 14.5 0.5 0.037 13.7 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KRH91928.1 - 0.027 13.9 1.6 1 8.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF2318 PF10080.4 KRH91928.1 - 0.14 11.9 2.0 0.19 11.5 0.5 1.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) Lar_restr_allev PF14354.1 KRH91928.1 - 0.18 12.1 0.8 0.93 9.8 0.5 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ima1_N PF09779.4 KRH91928.1 - 0.24 11.8 10.2 0.048 14.1 4.1 1.9 1 1 1 2 2 2 0 Ima1 N-terminal domain GFA PF04828.9 KRH91928.1 - 0.35 10.8 2.5 2.5 8.1 1.7 2.3 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme ABC2_membrane_3 PF12698.2 KRH91928.1 - 0.42 9.6 4.2 0.51 9.3 2.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_1 PF00078.22 KRH91929.1 - 9.9e-20 70.8 0.4 1.6e-19 70.1 0.3 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_B_palm PF14792.1 KRH91929.1 - 0.08 13.0 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 DNA polymerase beta palm CobU PF02283.11 KRH91929.1 - 0.087 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RVT_2 PF07727.9 KRH91929.1 - 0.092 11.6 0.2 0.43 9.5 0.1 1.9 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH91930.1 - 0.00068 19.1 0.1 0.00093 18.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase thumb domain NOSIC PF08060.8 KRH91931.1 - 0.044 13.6 0.3 0.09 12.5 0.2 1.5 1 0 0 1 1 1 0 NOSIC (NUC001) domain DDE_3 PF13358.1 KRH91933.1 - 0.00099 18.8 0.0 0.001 18.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF814 PF05670.8 KRH91935.1 - 4.6e-07 29.6 1.4 6.6e-07 29.1 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF814) tRNA-synt_1b PF00579.20 KRH91935.1 - 1.9 7.5 8.0 4.2 6.4 5.6 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (W and Y) ER_lumen_recept PF00810.13 KRH91936.1 - 2.1e-36 125.5 20.1 3.3e-36 124.9 14.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor gag-asp_proteas PF13975.1 KRH91938.1 - 0.031 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 KRH91940.1 - 2.3e-19 69.6 0.2 3.5e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zw10 PF06248.8 KRH91940.1 - 0.012 13.7 0.4 0.017 13.3 0.3 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 RhoGEF PF00621.15 KRH91940.1 - 0.17 11.7 4.9 0.98 9.2 0.2 2.1 1 1 1 2 2 2 0 RhoGEF domain MOZ_SAS PF01853.13 KRH91941.1 - 4.8e-24 84.6 0.8 8.1e-24 83.8 0.5 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KRH91941.1 - 7.1e-10 38.4 0.2 1.8e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 KRH91941.1 - 0.1 12.9 0.6 0.31 11.4 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type EVC2_like PF12297.3 KRH91942.1 - 0.065 11.8 0.4 0.081 11.5 0.3 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF3642 PF12182.3 KRH91942.1 - 0.4 11.1 4.5 0.28 11.6 1.6 1.7 2 0 0 2 2 2 0 Bacterial lipoprotein YoqO PF14037.1 KRH91942.1 - 0.76 9.9 5.6 0.91 9.6 0.2 2.8 3 0 0 3 3 3 0 YoqO-like protein HATPase_c PF02518.21 KRH91943.1 - 4.4e-08 32.8 0.0 6.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KRH91943.1 - 0.002 17.7 0.6 0.003 17.2 0.4 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3590 PF12148.3 KRH91944.1 - 0.68 9.5 6.6 18 4.9 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3590) DUF1034 PF06280.7 KRH91944.1 - 1.4 9.3 9.7 4 7.8 3.9 2.0 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) DUF3591 PF12157.3 KRH91944.1 - 1.8 6.8 11.8 3.3 6.0 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3591) GIY-YIG PF01541.19 KRH91944.1 - 3.1 8.2 11.3 2.2e+02 2.2 7.8 2.6 1 1 0 1 1 1 0 GIY-YIG catalytic domain DUF3504 PF12012.3 KRH91944.1 - 9.8 5.9 10.9 13 5.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Yippee-Mis18 PF03226.9 KRH91945.1 - 0.017 15.1 3.1 0.29 11.2 2.0 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RestrictionMunI PF11407.3 KRH91945.1 - 0.024 14.2 0.1 0.038 13.6 0.0 1.3 1 1 0 1 1 1 0 Type II restriction enzyme MunI Homeobox PF00046.24 KRH91946.1 - 3.2e-15 55.4 1.8 6.3e-15 54.5 1.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH91946.1 - 4.2e-11 42.3 0.5 9.3e-11 41.2 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_19 PF12844.2 KRH91946.1 - 0.023 14.7 0.6 4.8 7.3 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Mpp10 PF04006.7 KRH91947.1 - 8.6e-07 27.7 16.1 1.3e-06 27.0 9.7 2.2 1 1 1 2 2 2 1 Mpp10 protein DUF2805 PF10985.3 KRH91947.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Syntaxin_2 PF14523.1 KRH91948.1 - 0.023 14.7 1.4 0.048 13.7 0.9 1.6 1 0 0 1 1 1 0 Syntaxin-like protein DUF1664 PF07889.7 KRH91948.1 - 0.05 13.4 4.8 0.43 10.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4116 PF13475.1 KRH91948.1 - 0.074 12.5 3.3 7.2 6.1 2.3 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) DASH_Duo1 PF08651.5 KRH91948.1 - 0.19 11.3 2.3 0.43 10.1 1.6 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 DASH_Dad4 PF08650.5 KRH91948.1 - 1.5 8.7 8.9 3.8 7.4 5.8 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad4 tRNA-synt_1b PF00579.20 KRH91949.1 - 3e-13 49.5 0.0 3.5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Rep_fac_C PF08542.6 KRH91949.1 - 0.12 12.3 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain EF-hand_1 PF00036.27 KRH91950.1 - 4.1e-11 41.3 9.8 1.3e-06 27.2 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 KRH91950.1 - 5.8e-11 42.3 2.2 1e-08 35.1 0.3 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KRH91950.1 - 1e-10 40.5 1.3 0.00045 19.8 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KRH91950.1 - 2.2e-09 36.2 0.4 5.6e-05 22.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KRH91950.1 - 1.1e-08 34.5 0.8 1.1e-06 28.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KRH91950.1 - 0.028 14.4 0.1 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_lysozyme PF00959.14 KRH91950.1 - 0.037 14.3 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Phage lysozyme Lipin_N PF04571.9 KRH91951.1 - 5.2e-10 38.9 0.1 7.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 lipin, N-terminal conserved region CDtoxinA PF03498.9 KRH91952.1 - 0.0039 16.5 0.8 0.011 15.1 0.4 1.5 1 1 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 KRH91952.1 - 0.0075 16.6 0.0 0.036 14.4 0.0 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like FliW PF02623.10 KRH91953.1 - 0.019 14.4 1.5 2.8 7.5 0.1 2.5 2 0 0 2 2 2 0 FliW protein zf-C2H2_4 PF13894.1 KRH91954.1 - 0.056 13.8 0.2 0.16 12.3 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Yippee-Mis18 PF03226.9 KRH91954.1 - 0.089 12.8 0.2 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DDE_Tnp_IS1595 PF12762.2 KRH91955.1 - 0.00019 21.3 0.0 0.00021 21.1 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain GalKase_gal_bdg PF10509.4 KRH91957.1 - 0.028 13.7 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Galactokinase galactose-binding signature RNase_H PF00075.19 KRH91959.1 - 0.00067 19.9 0.0 0.0017 18.6 0.0 1.7 1 1 0 1 1 1 1 RNase H F_bP_aldolase PF01116.15 KRH91959.1 - 0.0046 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Rhodanese PF00581.15 KRH91960.1 - 6.4e-17 61.9 0.0 1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain TLD PF07534.11 KRH91962.1 - 3.8e-31 107.9 2.5 4.6e-31 107.6 1.7 1.1 1 0 0 1 1 1 1 TLD Glyco_transf_20 PF00982.16 KRH91963.1 - 2.6e-23 82.2 0.8 2e-21 76.0 0.1 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KRH91963.1 - 0.018 14.4 0.3 0.077 12.4 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferases group 1 Spo0A_C PF08769.6 KRH91963.1 - 0.029 14.2 0.1 0.24 11.2 0.1 2.4 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SPARC_Ca_bdg PF10591.4 KRH91963.1 - 4.5 7.3 9.3 0.38 10.7 1.5 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Glyco_transf_20 PF00982.16 KRH91964.1 - 1.3e-23 83.2 1.0 1.8e-21 76.1 0.1 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KRH91964.1 - 0.028 13.8 0.4 0.1 12.0 0.0 2.1 1 1 0 2 2 2 0 Glycosyl transferases group 1 Spo0A_C PF08769.6 KRH91964.1 - 0.031 14.1 0.1 0.25 11.2 0.1 2.4 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SPARC_Ca_bdg PF10591.4 KRH91964.1 - 3.3 7.7 9.2 0.38 10.7 1.5 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region HIT PF01230.18 KRH91965.1 - 2.7e-17 63.0 2.3 4.2e-17 62.4 1.6 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KRH91965.1 - 1.5e-08 34.8 3.2 3e-08 33.9 2.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KRH91965.1 - 0.00013 21.5 3.5 0.00021 20.9 2.4 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 rve PF00665.21 KRH91966.1 - 5.9e-10 39.3 0.2 3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH91966.1 - 5.5e-05 22.6 0.1 0.00012 21.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4537 PF15057.1 KRH91966.1 - 0.0079 15.9 0.5 0.013 15.2 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Streptin-Immun PF11083.3 KRH91966.1 - 0.023 14.6 1.9 0.023 14.6 1.3 1.9 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein LOH1CR12 PF10158.4 KRH91966.1 - 0.11 12.3 1.9 0.15 11.8 0.3 2.0 2 0 0 2 2 2 0 Tumour suppressor protein HATPase_c_3 PF13589.1 KRH91967.1 - 7.6e-14 51.5 0.1 1.3e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KRH91967.1 - 4e-08 32.9 0.0 6.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.13 KRH91967.1 - 1.1e-05 24.0 3.1 1.6e-05 23.5 2.2 1.2 1 0 0 1 1 1 1 Hsp90 protein RNA_pol_A_bac PF01000.21 KRH91968.1 - 5.5e-17 61.9 0.2 8.7e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KRH91968.1 - 0.00031 19.8 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CSL PF05207.8 KRH91968.1 - 0.047 13.2 0.6 0.093 12.2 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF2443 PF10398.4 KRH91968.1 - 0.082 12.7 0.3 0.53 10.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DUF4391 PF14335.1 KRH91969.1 - 0.0015 17.9 1.2 0.0017 17.7 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) MSV199 PF10553.4 KRH91969.1 - 0.28 11.0 3.6 0.31 10.9 2.5 1.1 1 0 0 1 1 1 0 MSV199 domain Shugoshin_N PF07558.6 KRH91969.1 - 0.36 10.5 2.5 0.47 10.1 1.8 1.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region RRS1 PF04939.7 KRH91970.1 - 6.7e-12 45.1 6.2 8e-12 44.9 4.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) rve PF00665.21 KRH91973.1 - 3.1e-06 27.2 0.0 4.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH91973.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.5 2 0 0 2 2 2 0 DDE domain MULE PF10551.4 KRH91973.1 - 0.094 12.8 0.1 0.49 10.5 0.0 1.9 1 1 1 2 2 2 0 MULE transposase domain rve PF00665.21 KRH91975.1 - 4.2e-07 30.1 0.0 5.2e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DASH_Duo1 PF08651.5 KRH91975.1 - 0.038 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 Sec8_exocyst PF04048.9 KRH91975.1 - 0.09 12.4 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF2318 PF10080.4 KRH91976.1 - 0.00065 19.4 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) PKI PF02827.11 KRH91976.1 - 0.087 12.9 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor CCDC144C PF14915.1 KRH91977.1 - 0.013 14.3 3.7 0.022 13.6 2.5 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Leukemia_assc_2 PF15197.1 KRH91977.1 - 0.74 9.5 6.2 0.12 12.0 0.9 2.2 2 0 0 2 2 2 0 Leukemia-associated protein 2 TFIIA_gamma_N PF02268.11 KRH91978.1 - 1e-13 50.6 0.3 1.6e-13 50.0 0.2 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KRH91978.1 - 0.0089 15.8 0.6 0.022 14.5 0.1 1.8 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit DUF836 PF05768.9 KRH91978.1 - 0.016 15.4 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Gti1_Pac2 PF09729.4 KRH91980.1 - 1e-34 119.8 1.6 3.6e-28 98.5 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DDE_Tnp_IS1595 PF12762.2 KRH91981.1 - 3.3e-22 78.9 0.3 4e-22 78.6 0.2 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain vATP-synt_E PF01991.13 KRH91982.1 - 1.8e-20 73.0 19.1 3.6e-20 72.0 13.2 1.5 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Alpha-amylase PF00128.19 KRH91982.1 - 0.0089 15.4 1.6 0.01 15.2 1.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF2860 PF11059.3 KRH91982.1 - 0.081 11.9 1.0 0.14 11.1 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2860) ATP-synt_ab_N PF02874.18 KRH91983.1 - 0.073 13.2 0.4 0.083 13.1 0.3 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L13 PF00572.13 KRH91984.1 - 6.6e-18 64.9 0.1 1.2e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 Npa1 PF11707.3 KRH91985.1 - 0.034 13.1 4.8 0.061 12.3 3.2 1.5 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal Vps39_1 PF10366.4 KRH91985.1 - 0.8 9.7 4.7 1 9.4 0.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 ATP_bind_4 PF01902.12 KRH91986.1 - 1.2e-26 93.4 0.5 2.5e-26 92.4 0.4 1.5 1 1 0 1 1 1 1 ATP-binding region DUF2465 PF10239.4 KRH91986.1 - 0.009 15.2 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Ribosomal_L22 PF00237.14 KRH91987.1 - 3.4e-20 71.9 0.8 4.2e-20 71.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e zf-C2H2_jaz PF12171.3 KRH91988.1 - 0.0084 16.2 2.4 0.0084 16.2 1.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 KRH91988.1 - 0.76 9.6 3.2 1.3 8.9 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger domain RicinB_lectin_2 PF14200.1 KRH91989.1 - 0.0078 16.5 0.1 0.04 14.2 0.1 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KRH91989.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 KRH91989.1 - 0.044 13.1 0.0 0.073 12.4 0.0 1.4 1 1 0 1 1 1 0 Cytolethal distending toxin A/C family SET PF00856.23 KRH91990.1 - 0.00027 21.2 0.0 0.001 19.4 0.0 2.0 1 1 0 1 1 1 1 SET domain RicinB_lectin_2 PF14200.1 KRH91991.1 - 0.0069 16.7 0.1 0.053 13.8 0.1 1.9 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KRH91991.1 - 0.018 15.1 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 KRH91991.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.4 1 1 0 1 1 1 0 Cytolethal distending toxin A/C family CHASE3 PF05227.8 KRH91992.1 - 0.0022 17.6 0.4 0.0055 16.3 0.1 1.7 1 1 0 1 1 1 1 CHASE3 domain Pentapeptide_4 PF13599.1 KRH91994.1 - 2.2e-05 24.1 0.8 0.0021 17.8 0.5 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) HC2 PF07382.6 KRH91994.1 - 0.066 13.0 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 BCHF PF07284.6 KRH91994.1 - 0.23 11.2 16.9 1 9.1 3.1 2.2 1 1 1 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Gal-3-0_sulfotr PF06990.6 KRH91996.1 - 0.0034 16.0 0.7 0.0042 15.8 0.5 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Proteasome PF00227.21 KRH91997.1 - 4.2e-40 137.0 1.3 5.6e-40 136.6 0.9 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KRH91997.1 - 1.2e-09 37.3 1.3 1.4e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Asp_protease_2 PF13650.1 KRH91998.1 - 2.4e-07 31.1 0.1 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KRH91998.1 - 5.8e-06 26.2 0.0 9.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH91998.1 - 1.1e-05 25.1 0.0 2.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH91998.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_L35Ae PF01247.13 KRH91999.1 - 1.5e-18 66.3 1.5 1.8e-17 62.8 1.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KRH91999.1 - 1.8e-06 27.8 0.7 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 RimM N-terminal domain DDE_Tnp_IS1595 PF12762.2 KRH92000.1 - 1.2e-28 99.8 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH92000.1 - 0.1 12.0 2.3 0.38 10.2 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) DUF3157 PF11355.3 KRH92001.1 - 0.071 12.3 0.0 0.071 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) SMC_N PF02463.14 KRH92002.1 - 7.3e-20 71.1 0.3 3.1e-12 46.2 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KRH92002.1 - 8.8e-06 25.8 3.0 6.5e-05 23.0 2.1 2.0 1 1 0 1 1 1 1 AAA domain Pup PF05639.6 KRH92002.1 - 0.018 15.4 2.8 0.031 14.7 0.0 2.4 2 1 0 2 2 2 0 Pup-like protein SbcCD_C PF13558.1 KRH92002.1 - 0.021 14.7 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2205 PF10224.4 KRH92002.1 - 1.2 8.7 6.3 3 7.4 4.4 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Tantalus PF15386.1 KRH92003.1 - 0.93 9.3 8.7 1.5 8.6 6.1 1.5 1 1 0 1 1 1 0 Drosophila Tantalus-like Ribosomal_L6e PF01159.14 KRH92004.1 - 0.00014 22.0 0.4 0.0081 16.3 0.1 2.3 1 1 1 2 2 2 2 Ribosomal protein L6e Metalloenzyme PF01676.13 KRH92007.1 - 2.3e-50 171.3 0.4 2.7e-50 171.0 0.3 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KRH92007.1 - 0.00091 18.6 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 KRH92007.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.4 1 1 0 1 1 1 1 PglZ domain tRNA-synt_1b PF00579.20 KRH92008.1 - 0.0014 17.7 0.0 0.0032 16.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Pro_isomerase PF00160.16 KRH92009.1 - 1.1e-44 152.4 0.7 1.2e-44 152.2 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sugar_tr PF00083.19 KRH92010.1 - 9.7e-08 30.9 15.2 3.3e-07 29.2 10.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KRH92010.1 - 3.6e-06 25.9 12.3 7.2e-06 24.9 6.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PIG-F PF06699.6 KRH92010.1 - 0.015 15.2 1.0 0.015 15.2 0.7 2.0 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F RSN1_TM PF13967.1 KRH92010.1 - 0.059 12.9 0.2 0.059 12.9 0.2 1.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport DUF4231 PF14015.1 KRH92010.1 - 9.3 6.2 6.5 5 7.1 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) rve PF00665.21 KRH92012.1 - 0.0078 16.3 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain S4 PF01479.20 KRH92014.1 - 1.2e-08 34.2 0.2 2.1e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 S4 domain RestrictionMunI PF11407.3 KRH92014.1 - 0.028 14.0 1.0 0.15 11.6 0.1 2.0 1 1 1 2 2 2 0 Type II restriction enzyme MunI HECT_2 PF09814.4 KRH92017.1 - 1.3e-05 24.0 4.5 2.3e-05 23.2 3.1 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RVT_1 PF00078.22 KRH92019.1 - 6.4e-15 55.0 0.0 7e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH92019.1 - 0.042 12.8 0.2 0.052 12.5 0.1 1.2 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PRD_Mga PF08270.6 KRH92019.1 - 0.081 12.1 0.1 0.091 12.0 0.1 1.0 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain RNA_pol_Rpb2_6 PF00562.23 KRH92020.1 - 5.7e-40 137.2 6.9 2.2e-39 135.3 4.7 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Mem_trans PF03547.13 KRH92020.1 - 0.31 9.2 1.3 0.31 9.3 0.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Histone PF00125.19 KRH92022.1 - 2.6e-11 43.4 0.2 5.6e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KRH92022.1 - 0.006 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SIR2 PF02146.12 KRH92023.1 - 7.4e-20 71.4 0.1 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-ribbon_3 PF13248.1 KRH92023.1 - 0.081 12.1 0.3 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KRH92023.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon DDE_Tnp_IS1595 PF12762.2 KRH92024.1 - 9.9e-06 25.4 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain ABC_tran PF00005.22 KRH92025.1 - 1.5e-05 25.3 0.9 3.8e-05 24.0 0.1 1.8 1 1 1 2 2 2 1 ABC transporter AAA_16 PF13191.1 KRH92025.1 - 3.7e-05 23.7 0.0 8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 KRH92025.1 - 4.6e-05 23.8 2.0 5e-05 23.7 0.3 1.7 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KRH92025.1 - 4.6e-05 22.6 0.0 6.3e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 KRH92025.1 - 0.0001 21.3 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KRH92025.1 - 0.00013 22.0 0.1 0.00045 20.3 0.0 1.8 1 1 2 3 3 3 1 AAA domain AAA_29 PF13555.1 KRH92025.1 - 0.00016 21.1 0.1 0.0003 20.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KRH92025.1 - 0.00076 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KRH92025.1 - 0.001 18.8 0.2 0.0028 17.3 0.0 1.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 KRH92025.1 - 0.0038 18.0 0.1 0.0097 16.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KRH92025.1 - 0.0042 16.5 0.1 0.0068 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain DUF3596 PF12167.3 KRH92025.1 - 0.0044 16.5 0.1 0.006 16.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3596) AAA_21 PF13304.1 KRH92025.1 - 0.005 16.8 1.9 0.012 15.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KRH92025.1 - 0.0052 16.7 0.3 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 KRH92025.1 - 0.006 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KRH92025.1 - 0.0065 15.9 0.1 0.0088 15.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KRH92025.1 - 0.0087 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KRH92025.1 - 0.01 15.4 0.1 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SMC_N PF02463.14 KRH92025.1 - 0.014 14.5 0.2 0.022 13.9 0.1 1.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 KRH92025.1 - 0.016 15.7 0.0 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 KRH92025.1 - 0.016 15.3 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KRH92025.1 - 0.017 14.7 0.2 0.042 13.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KRH92025.1 - 0.023 13.5 0.6 0.11 11.3 0.1 1.9 1 1 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KRH92025.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KRH92025.1 - 0.032 13.7 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 KRH92025.1 - 0.041 12.5 0.0 0.046 12.4 0.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain AAA_14 PF13173.1 KRH92025.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 KRH92025.1 - 0.05 13.3 0.1 0.085 12.5 0.0 1.5 2 0 0 2 2 1 0 NTPase Septin PF00735.13 KRH92025.1 - 0.051 12.5 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 KRH92025.1 - 0.055 13.7 0.1 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KRH92025.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KRH92025.1 - 0.059 12.7 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 KRH92025.1 - 0.063 12.8 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 KRH92025.1 - 0.064 12.6 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KRH92025.1 - 0.072 12.5 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 KRH92025.1 - 0.093 11.3 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Dynamin_N PF00350.18 KRH92025.1 - 0.093 12.5 0.1 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Dynamin family Mg_chelatase PF01078.16 KRH92025.1 - 0.13 11.4 0.1 0.36 9.9 0.1 1.6 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KRH92025.1 - 0.16 11.5 0.2 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.1 KRH92026.1 - 6.2e-08 32.5 0.0 8.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 KRH92026.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF2301 PF10063.4 KRH92027.1 - 0.13 12.5 0.1 0.13 12.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FlaG PF03646.10 KRH92028.1 - 0.51 10.5 4.7 0.2 11.8 0.3 1.9 2 0 0 2 2 2 0 FlaG protein Ricin_B_lectin PF00652.17 KRH92029.1 - 0.0014 18.6 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KRH92029.1 - 0.0055 17.0 0.0 0.032 14.6 0.0 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like DUF290 PF01060.18 KRH92029.1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.7 1 1 0 1 1 1 0 Transthyretin-like family rve PF00665.21 KRH92031.1 - 4.2e-09 36.5 0.0 6.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92031.1 - 0.0021 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 DDE domain Inhibitor_I67 PF11405.3 KRH92031.1 - 0.25 11.4 2.2 18 5.4 0.7 2.9 3 0 0 3 3 3 0 Bromelain inhibitor VI tRNA-synt_His PF13393.1 KRH92032.1 - 1.1e-20 73.9 0.0 1.6e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 KRH92032.1 - 1.3e-07 31.5 0.9 2.1e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Anticodon binding domain Telomere_Sde2_2 PF13297.1 KRH92032.1 - 0.075 12.3 0.1 0.34 10.2 0.0 2.1 2 1 1 3 3 3 0 Telomere stability C-terminal Ras PF00071.17 KRH92033.1 - 2.9e-48 163.3 0.4 3.6e-48 163.0 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH92033.1 - 2.8e-20 72.9 0.0 4.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KRH92033.1 - 3.3e-15 55.7 0.1 3.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KRH92033.1 - 6.1e-09 35.5 0.0 2.7e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KRH92033.1 - 4.7e-08 32.4 0.1 6.2e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KRH92033.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KRH92033.1 - 0.0001 21.5 0.1 0.00014 21.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KRH92033.1 - 0.0014 17.3 4.1 0.021 13.5 1.4 2.5 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 KRH92033.1 - 0.0027 17.8 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KRH92033.1 - 0.013 15.2 0.3 0.016 14.9 0.2 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 KRH92033.1 - 0.032 13.7 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KRH92033.1 - 0.05 13.5 1.1 0.13 12.1 0.6 1.8 1 1 0 1 1 1 0 AAA domain DEDD_Tnp_IS110 PF01548.12 KRH92034.1 - 0.16 11.6 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Transposase rve_3 PF13683.1 KRH92035.1 - 3.6e-06 26.3 0.1 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve PF00665.21 KRH92035.1 - 2.1e-05 24.6 0.1 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Synaptobrevin PF00957.16 KRH92037.1 - 1.2e-07 31.1 2.2 1.7e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 Synaptobrevin Clat_adaptor_s PF01217.15 KRH92037.1 - 0.037 13.7 3.2 0.049 13.3 1.9 1.3 1 1 0 1 1 1 0 Clathrin adaptor complex small chain DUF4413 PF14372.1 KRH92037.1 - 0.046 13.7 1.0 0.09 12.7 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) DUF1940 PF09155.5 KRH92037.1 - 0.058 13.2 0.2 0.058 13.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1940) YpjP PF14005.1 KRH92037.1 - 0.086 12.6 0.7 0.17 11.6 0.2 1.6 1 1 0 1 1 1 0 YpjP-like protein Erf4 PF10256.4 KRH92037.1 - 0.27 11.1 3.9 0.61 9.9 2.7 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Abhydrolase_2 PF02230.11 KRH92040.1 - 2.8e-15 56.3 0.0 3.1e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 KRH92040.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KRH92040.1 - 0.00045 19.9 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KRH92040.1 - 0.0031 16.9 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.15 KRH92040.1 - 0.0037 16.7 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase UPF0565 PF10561.4 KRH92040.1 - 0.0087 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 AXE1 PF05448.7 KRH92040.1 - 0.014 13.9 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 KRH92040.1 - 0.019 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KRH92040.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 KRH92040.1 - 0.039 12.2 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 KRH92040.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KRH92040.1 - 0.082 12.7 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KRH92040.1 - 0.12 11.9 0.2 0.61 9.6 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cas_GSU0053 PF09617.5 KRH92041.1 - 0.1 12.3 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Tub_2 PF04525.7 KRH92042.1 - 0.012 14.9 0.6 0.02 14.2 0.3 1.4 1 1 0 1 1 1 0 Tubby C 2 dCMP_cyt_deam_1 PF00383.17 KRH92043.1 - 2e-06 27.4 0.2 3e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Str_synth PF03088.11 KRH92044.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Strictosidine synthase RRM_1 PF00076.17 KRH92045.1 - 8.2e-09 34.9 0.1 0.00068 19.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH92045.1 - 3.3e-07 30.0 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92045.1 - 1.9e-06 27.7 0.2 0.075 13.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) rve PF00665.21 KRH92046.1 - 1.5e-09 37.9 0.0 1.6e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain ATP-cone PF03477.11 KRH92046.1 - 0.013 15.8 0.6 0.017 15.5 0.4 1.1 1 0 0 1 1 1 0 ATP cone domain Colicin_Pyocin PF01320.13 KRH92046.1 - 0.1 12.4 3.9 0.11 12.3 0.2 2.0 1 1 1 2 2 2 0 Colicin immunity protein / pyocin immunity protein LAGLIDADG_3 PF14528.1 KRH92046.1 - 0.12 12.6 0.3 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 LAGLIDADG-like domain RVT_1 PF00078.22 KRH92047.1 - 1.1e-16 60.8 0.1 2e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V_ATPase_I PF01496.14 KRH92048.1 - 7.5e-09 34.0 9.3 1.8e-08 32.7 6.5 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DED PF01335.16 KRH92048.1 - 1.7 8.7 8.5 1.1 9.3 1.9 3.3 2 2 2 4 4 4 0 Death effector domain DASH_Dad2 PF08654.5 KRH92048.1 - 8 6.5 7.6 0.41 10.6 0.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 Herpes_UL69 PF05459.7 KRH92049.1 - 0.0066 15.6 1.2 0.016 14.4 0.5 1.8 1 1 1 2 2 2 1 Herpesvirus transcriptional regulator family Ndc80_HEC PF03801.8 KRH92049.1 - 1.7 8.0 6.1 0.93 8.9 0.7 2.3 2 0 0 2 2 2 0 HEC/Ndc80p family ERCC4 PF02732.10 KRH92050.1 - 4.4e-16 58.9 0.2 7.5e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 KRH92050.1 - 0.00022 20.9 0.9 0.00055 19.7 0.6 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix MarR PF01047.17 KRH92050.1 - 0.0072 16.0 0.2 0.036 13.7 0.1 2.2 2 1 0 2 2 2 1 MarR family Topoisom_bac PF01131.15 KRH92050.1 - 0.01 14.6 0.1 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 DNA topoisomerase Branch PF02485.16 KRH92050.1 - 0.019 14.1 0.1 0.047 12.8 0.0 1.6 1 0 0 1 1 1 0 Core-2/I-Branching enzyme ubiquitin PF00240.18 KRH92051.1 - 2.5e-09 36.3 0.6 5.4e-09 35.3 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.3 KRH92051.1 - 0.00086 19.5 1.2 0.0019 18.4 0.8 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Diphthamide_syn PF01866.12 KRH92052.1 - 1.2e-09 37.8 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SelP_N PF04592.9 KRH92052.1 - 0.12 11.7 7.7 0.16 11.3 5.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KRH92052.1 - 0.6 9.0 2.6 0.56 9.1 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CTP_transf_2 PF01467.21 KRH92054.1 - 1.8e-10 41.1 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KRH92054.1 - 0.00033 20.3 0.1 0.0016 18.0 0.0 2.0 1 1 1 2 2 2 1 FAD synthetase Pantoate_ligase PF02569.10 KRH92054.1 - 0.013 14.2 0.0 0.015 14.0 0.0 1.3 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase DFF40 PF09230.5 KRH92054.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa zf-C4_ClpX PF06689.8 KRH92054.1 - 0.095 12.2 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 ClpX C4-type zinc finger DUF2974 PF11187.3 KRH92054.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) GATase_7 PF13537.1 KRH92055.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KRH92055.1 - 0.12 12.3 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain NTP_transferase PF00483.18 KRH92056.1 - 8.6e-45 152.9 0.0 9.8e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KRH92056.1 - 1.8e-07 31.4 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_2 PF01467.21 KRH92057.1 - 1.8e-10 41.1 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KRH92057.1 - 0.00035 20.2 0.0 0.0016 18.1 0.0 2.0 1 1 1 2 2 2 1 FAD synthetase Pantoate_ligase PF02569.10 KRH92057.1 - 0.014 14.2 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DFF40 PF09230.5 KRH92057.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Topoisom_bac PF01131.15 KRH92059.1 - 6.5e-17 61.4 0.0 2.4e-12 46.4 0.0 2.4 2 1 0 2 2 2 2 DNA topoisomerase Ribosomal_S19e PF01090.14 KRH92060.1 - 1.6e-22 79.4 0.0 3.8e-14 52.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S19e HTH_45 PF14947.1 KRH92060.1 - 0.056 13.2 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix Mrr_N PF14338.1 KRH92060.1 - 0.083 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Mrr N-terminal domain MGDG_synth PF06925.6 KRH92060.1 - 0.12 12.2 0.6 0.33 10.8 0.4 1.8 1 1 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Lipase3_N PF03893.11 KRH92060.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase 3 N-terminal region UCH PF00443.24 KRH92062.1 - 1.5e-10 40.6 0.2 1.8e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH92062.1 - 0.039 13.4 2.8 0.07 12.5 1.9 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S8 PF00410.14 KRH92063.1 - 1.3e-15 57.3 0.1 1.8e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DCAF15_WD40 PF14939.1 KRH92064.1 - 0.014 14.7 5.1 0.017 14.5 3.5 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF2833 PF11090.3 KRH92065.1 - 0.068 13.3 0.2 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2833) DNA_gyraseB PF00204.20 KRH92066.1 - 7e-22 77.4 2.4 1.3e-21 76.5 1.6 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KRH92066.1 - 2.3e-14 53.1 0.4 6e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Toprim domain WD40 PF00400.27 KRH92067.1 - 6.9e-11 41.5 0.1 0.0001 22.0 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat GCS PF03074.11 KRH92068.1 - 1.9e-08 33.7 0.0 4.2e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 Glutamate-cysteine ligase TPR_1 PF00515.23 KRH92069.1 - 2.3e-27 93.4 17.4 1.8e-07 30.4 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KRH92069.1 - 1.2e-25 87.2 7.0 7.5e-05 22.3 0.0 6.3 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 KRH92069.1 - 1.4e-23 80.8 13.5 0.00039 19.9 0.3 6.4 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 KRH92069.1 - 2.3e-22 78.3 6.9 1.7e-06 27.5 0.1 4.6 2 1 1 4 4 4 4 TPR repeat TPR_12 PF13424.1 KRH92069.1 - 1.3e-20 73.0 2.6 0.00028 20.7 0.0 5.7 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KRH92069.1 - 5.3e-14 50.8 0.1 0.016 14.9 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KRH92069.1 - 1.7e-12 47.6 0.0 0.0021 18.6 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KRH92069.1 - 1.2e-08 35.1 0.0 0.54 10.6 0.0 3.8 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KRH92069.1 - 2.4e-08 33.8 0.0 0.94 10.3 0.0 4.9 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KRH92069.1 - 2.7e-08 33.7 2.4 1 9.9 0.2 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KRH92069.1 - 9.9e-08 31.6 2.3 0.0041 17.1 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 KRH92069.1 - 3.7e-07 29.8 0.0 1 9.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KRH92069.1 - 1.7e-05 24.8 12.7 0.02 15.0 0.1 4.0 1 1 4 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KRH92069.1 - 0.00014 21.6 0.0 0.85 9.5 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat Tcf25 PF04910.9 KRH92069.1 - 0.00066 18.7 0.0 0.039 12.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional repressor TCF25 DUF627 PF04781.7 KRH92069.1 - 0.0061 16.1 2.2 0.54 9.9 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF627) Sel1 PF08238.7 KRH92069.1 - 3 8.6 6.8 16 6.2 0.0 4.6 5 1 0 5 5 5 0 Sel1 repeat tRNA-synt_2 PF00152.15 KRH92071.1 - 8.6e-65 218.7 0.0 9.5e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KRH92071.1 - 7.9e-06 25.2 0.1 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Syja_N PF02383.13 KRH92072.1 - 2.4e-05 23.2 6.4 0.00035 19.4 0.7 2.4 2 1 1 3 3 3 2 SacI homology domain UL11 PF11094.3 KRH92075.1 - 0.056 13.2 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated tegument protein zf-H2C2 PF09337.5 KRH92075.1 - 0.14 11.5 1.2 0.21 11.0 0.8 1.3 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ELO PF01151.13 KRH92076.1 - 7.2e-47 159.7 27.9 8.9e-47 159.4 19.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Helicase_C PF00271.26 KRH92077.1 - 9.9e-07 28.5 0.0 6.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pkinase PF00069.20 KRH92078.1 - 5.6e-54 183.0 0.1 6.4e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92078.1 - 2.2e-27 95.7 0.0 2.7e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH92078.1 - 1.2e-08 34.2 0.0 1.9e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KRH92078.1 - 2.4e-05 23.4 0.0 4.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KRH92078.1 - 0.0004 19.7 0.2 0.00058 19.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KRH92078.1 - 0.0026 17.5 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4085 PF13315.1 KRH92078.1 - 0.0089 15.4 0.1 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4085) Fmp27_SW PF10305.4 KRH92080.1 - 1.2 9.6 5.7 0.99 9.8 0.1 2.7 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DDE_Tnp_1_7 PF13843.1 KRH92081.1 - 4.8e-47 160.7 11.0 5.3e-47 160.5 7.6 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.16 KRH92081.1 - 0.00015 21.3 1.6 0.012 15.1 0.0 2.1 2 0 0 2 2 2 2 Transposase DDE domain DDE_3 PF13358.1 KRH92082.1 - 0.0065 16.2 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2748 PF10871.3 KRH92082.1 - 0.011 14.2 2.1 0.012 14.0 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Pkinase PF00069.20 KRH92083.1 - 0.031 13.4 5.5 0.025 13.7 2.9 1.7 1 1 1 2 2 2 0 Protein kinase domain DDE_3 PF13358.1 KRH92084.1 - 2.6e-16 59.7 0.1 3.9e-16 59.1 0.0 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 KRH92084.1 - 0.056 13.5 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Gti1_Pac2 PF09729.4 KRH92085.1 - 9.9e-40 136.1 3.9 9.9e-40 136.1 2.7 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family Homeobox PF00046.24 KRH92086.1 - 5.3e-21 73.9 9.3 5.9e-21 73.8 2.8 2.2 1 1 1 2 2 2 1 Homeobox domain WYL PF13280.1 KRH92086.1 - 0.055 13.3 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 WYL domain Homeobox_KN PF05920.6 KRH92086.1 - 0.063 12.9 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Homeobox KN domain Tcp10_C PF07202.8 KRH92087.1 - 0.00031 20.3 1.2 0.00053 19.5 0.8 1.4 1 1 0 1 1 1 1 T-complex protein 10 C-terminus ETX_MTX2 PF03318.8 KRH92087.1 - 0.0091 15.5 0.3 0.011 15.3 0.2 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 OstA_2 PF13100.1 KRH92087.1 - 0.038 13.3 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 OstA-like protein TGT_C2 PF14810.1 KRH92087.1 - 0.11 12.3 0.6 1.5 8.7 0.1 2.3 2 1 1 3 3 3 0 Patch-forming domain C2 of tRNA-guanine transglycosylase PLDc_2 PF13091.1 KRH92088.1 - 5.3e-08 32.6 0.3 1.1e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 PLD-like domain FBA_2 PF07735.12 KRH92088.1 - 7.2 6.5 10.6 16 5.4 0.0 4.0 4 1 0 4 4 4 0 F-box associated ABC2_membrane PF01061.19 KRH92089.1 - 0.00029 20.0 7.7 0.00037 19.7 5.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter zf-C2H2_4 PF13894.1 KRH92090.1 - 1.9e-05 24.6 11.4 0.0055 16.9 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KRH92090.1 - 0.00046 20.3 10.3 0.038 14.2 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KRH92090.1 - 0.0032 17.7 13.8 0.005 17.0 0.2 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type Flag1_repress PF03614.8 KRH92090.1 - 0.18 11.3 2.2 0.32 10.5 0.2 2.0 1 1 1 2 2 2 0 Repressor of phase-1 flagellin zf-Di19 PF05605.7 KRH92090.1 - 1.2 9.2 6.5 3.9 7.6 0.9 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KRH92090.1 - 6.8 6.9 11.5 11 6.3 0.0 4.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.20 KRH92092.1 - 2e-40 138.5 3.1 2.4e-40 138.3 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92092.1 - 3.5e-24 85.2 0.2 3.9e-24 85.1 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KRH92092.1 - 0.00062 19.5 0.0 0.15 11.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KRH92092.1 - 0.0017 17.4 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KRH92092.1 - 0.044 13.3 3.9 0.13 11.8 2.7 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF4528 PF15031.1 KRH92092.1 - 0.093 12.4 1.8 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4528) Tetraspannin PF00335.15 KRH92093.1 - 1.1e-12 47.6 14.6 1.5e-12 47.3 10.2 1.1 1 0 0 1 1 1 1 Tetraspanin family SYS1 PF09801.4 KRH92093.1 - 1 9.3 9.8 15 5.5 4.8 2.6 2 1 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network DUF4577 PF15145.1 KRH92093.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) BatA PF07584.6 KRH92093.1 - 9.6 6.4 8.7 25 5.1 1.1 3.2 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Ribosomal_S24e PF01282.14 KRH92094.1 - 5.1e-12 45.4 2.1 7.4e-12 44.8 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Fiji_64_capsid PF05880.6 KRH92094.1 - 0.0016 16.8 0.7 0.0016 16.8 0.5 1.2 1 0 0 1 1 1 1 Fijivirus 64 kDa capsid protein DNA_pack_C PF02499.10 KRH92094.1 - 0.038 12.7 0.1 0.047 12.4 0.1 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus DUF4477 PF14780.1 KRH92094.1 - 0.059 12.7 0.6 0.071 12.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) EMP24_GP25L PF01105.19 KRH92095.1 - 2.6e-07 30.5 1.8 4e-07 29.9 1.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MoeZ_MoeB PF05237.8 KRH92095.1 - 0.056 13.0 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain Proteasome PF00227.21 KRH92096.1 - 1.4e-22 79.9 0.1 6.4e-21 74.5 0.1 2.0 1 1 0 1 1 1 1 Proteasome subunit DUF2805 PF10985.3 KRH92096.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Arg_repressor PF01316.16 KRH92097.1 - 1.3e-07 31.0 3.0 2.2e-07 30.3 2.1 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DDE_3 PF13358.1 KRH92097.1 - 6.6e-06 25.9 0.0 5.5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH92097.1 - 8.2e-05 22.5 2.8 8.2e-05 22.5 1.9 1.6 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.1 KRH92097.1 - 0.028 13.7 3.1 0.054 12.8 2.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SMC_N PF02463.14 KRH92098.1 - 1.6e-32 112.5 0.9 2e-32 112.2 0.6 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KRH92098.1 - 2.2e-07 31.1 15.2 3.1e-07 30.6 10.5 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KRH92098.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RST PF12174.3 KRH92098.1 - 0.23 11.2 3.6 0.21 11.4 0.5 2.3 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Adaptin_binding PF10199.4 KRH92098.1 - 8.3 6.6 12.2 13 6.0 8.5 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 UQ_con PF00179.21 KRH92099.1 - 2.6e-11 43.0 0.8 3.9e-11 42.5 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme rve PF00665.21 KRH92101.1 - 1.8e-08 34.5 0.1 5.1e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH92101.1 - 0.00054 19.4 0.2 0.0013 18.2 0.1 1.7 1 1 0 1 1 1 1 Integrase core domain Terminase_5 PF06056.7 KRH92102.1 - 0.027 14.0 2.2 10 5.7 0.0 3.2 2 1 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) Dimerisation PF08100.6 KRH92102.1 - 6.5 6.6 8.1 1.5e+02 2.3 0.1 4.4 4 2 0 4 4 4 0 Dimerisation domain ATP_bind_1 PF03029.12 KRH92103.1 - 8.4e-29 100.7 0.1 1.3e-17 64.2 0.1 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KRH92103.1 - 1.6e-06 28.4 0.0 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KRH92103.1 - 8.1e-06 25.7 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH92103.1 - 1.5e-05 25.0 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KRH92103.1 - 0.00013 22.7 0.1 0.00021 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 KRH92103.1 - 0.00015 21.2 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 KRH92103.1 - 0.00053 19.1 0.0 0.00092 18.3 0.0 1.4 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.1 KRH92103.1 - 0.0012 18.4 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KRH92103.1 - 0.0014 18.7 0.1 0.003 17.7 0.0 1.6 2 0 0 2 2 1 1 RNA helicase AAA_22 PF13401.1 KRH92103.1 - 0.0016 18.5 0.2 0.0068 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KRH92103.1 - 0.0025 18.1 0.0 0.0045 17.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA PF00004.24 KRH92103.1 - 0.0029 17.8 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KRH92103.1 - 0.003 17.0 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 KRH92103.1 - 0.003 17.0 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PRK PF00485.13 KRH92103.1 - 0.0043 16.6 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 KRH92103.1 - 0.0091 15.6 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KRH92103.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KRH92103.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KRH92103.1 - 0.02 14.3 0.1 0.04 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 KRH92103.1 - 0.025 13.2 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 KRH92103.1 - 0.027 14.1 0.0 0.035 13.7 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KRH92103.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KRH92103.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 KRH92103.1 - 0.035 13.3 0.0 0.066 12.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein ATP-synt_ab PF00006.20 KRH92103.1 - 0.048 13.1 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KRH92103.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KRH92103.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 KRH92103.1 - 0.082 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.10 KRH92103.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Miro PF08477.8 KRH92103.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 KRH92103.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FYRN PF05964.9 KRH92104.1 - 1.9e-07 30.3 0.3 3.5e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF2340 PF10209.4 KRH92104.1 - 0.007 16.5 1.5 0.51 10.5 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2340) FTA4 PF13093.1 KRH92104.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1785 PF08699.5 KRH92105.1 - 1e-09 37.5 0.0 2.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Ribosomal_60s PF00428.14 KRH92105.1 - 0.019 15.3 0.5 0.032 14.6 0.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOB1_Zn_bind PF08772.6 KRH92106.1 - 3.3e-07 30.0 1.3 6.3e-07 29.1 0.9 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Clp1 PF06807.9 KRH92107.1 - 0.00028 20.6 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Sulfatase PF00884.18 KRH92107.1 - 0.051 12.7 0.1 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulfatase eIF-5_eIF-2B PF01873.12 KRH92108.1 - 4.4e-30 103.9 2.9 6.2e-30 103.4 2.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arg_tRNA_synt_N PF03485.11 KRH92108.1 - 0.02 15.4 0.2 0.089 13.3 0.1 1.9 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain Elf1 PF05129.8 KRH92108.1 - 0.038 13.6 0.9 0.094 12.4 0.3 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.7 KRH92108.1 - 0.051 13.3 0.2 0.096 12.4 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons AHS1 PF02682.11 KRH92108.1 - 0.053 12.9 0.1 0.076 12.4 0.1 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 DUF2066 PF09839.4 KRH92108.1 - 0.054 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) TF_Zn_Ribbon PF08271.7 KRH92108.1 - 0.056 12.7 0.7 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding tRNA-synt_1f PF01921.13 KRH92108.1 - 0.1 11.2 0.3 0.13 10.9 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2296 PF10058.4 KRH92108.1 - 0.17 11.6 1.8 0.41 10.4 1.3 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 KRH92108.1 - 0.3 10.3 3.0 1.7 7.9 2.1 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Churchill PF06573.6 KRH92108.1 - 0.31 11.0 3.3 1.2 9.1 0.6 2.4 1 1 2 3 3 3 0 Churchill protein zf-RanBP PF00641.13 KRH92108.1 - 0.37 9.9 2.6 0.6 9.2 0.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others V_ATPase_I PF01496.14 KRH92109.1 - 1.4e-65 221.6 22.5 1.9e-65 221.1 15.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.14 KRH92110.1 - 1.2e-37 129.2 0.3 1.3e-37 129.1 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RSN1_TM PF13967.1 KRH92111.1 - 1.1e-19 70.5 11.4 1.6e-19 70.0 7.9 1.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport CbiQ PF02361.11 KRH92111.1 - 1.1 8.8 11.0 1.5 8.3 3.5 2.1 2 0 0 2 2 2 0 Cobalt transport protein Colicin_V PF02674.11 KRH92111.1 - 2.8 7.8 20.1 5.8 6.7 0.1 2.7 2 1 0 2 2 2 0 Colicin V production protein Ras PF00071.17 KRH92113.1 - 9.9e-38 129.0 0.3 1.2e-37 128.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH92113.1 - 6.7e-19 68.5 0.0 1e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KRH92113.1 - 1.2e-15 57.1 0.3 1.4e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KRH92113.1 - 2e-06 27.1 0.3 2.5e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KRH92113.1 - 4.7e-06 26.5 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 KRH92113.1 - 0.00014 20.9 1.1 0.15 11.0 0.3 2.1 2 0 0 2 2 2 2 Septin GTP_EFTU PF00009.22 KRH92113.1 - 0.00043 19.7 0.2 0.0046 16.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KRH92113.1 - 0.00044 19.7 1.0 0.001 18.5 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KRH92113.1 - 0.00052 19.2 0.4 0.0023 17.1 0.1 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MobB PF03205.9 KRH92113.1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KRH92113.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KRH92113.1 - 0.0043 16.9 0.7 0.0098 15.7 0.4 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KRH92113.1 - 0.0074 16.0 0.1 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase FeoB_N PF02421.13 KRH92113.1 - 0.0084 15.3 0.2 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KRH92113.1 - 0.057 13.2 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.12 KRH92113.1 - 0.094 12.2 0.1 1.1 8.7 0.0 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein PMT PF02366.13 KRH92114.1 - 1e-59 201.8 24.5 1.2e-59 201.6 17.0 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.1 KRH92114.1 - 0.00037 20.4 18.0 0.00037 20.4 12.5 2.9 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase rve PF00665.21 KRH92115.1 - 4.2e-18 65.5 0.0 2.2e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH92115.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 KRH92118.1 - 7.5e-05 22.8 0.1 0.00011 22.3 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92118.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DUF3915 PF13054.1 KRH92118.1 - 0.08 12.8 0.4 0.09 12.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) AIRC PF00731.15 KRH92118.1 - 0.089 12.0 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 AIR carboxylase zf-H2C2 PF09337.5 KRH92119.1 - 0.0019 17.5 4.0 0.0032 16.8 2.8 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Herpes_BLRF2 PF05812.7 KRH92119.1 - 0.071 12.9 0.5 0.1 12.3 0.3 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1874 PF08960.5 KRH92120.1 - 0.055 13.2 0.8 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1874) Peptidase_S39 PF02122.10 KRH92120.1 - 0.13 11.5 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase S39 rve PF00665.21 KRH92122.1 - 1.2e-24 86.6 0.0 2.4e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH92122.1 - 0.00035 19.9 3.3 0.00035 19.9 2.3 2.3 3 0 0 3 3 3 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 KRH92122.1 - 0.013 14.9 0.3 0.083 12.4 0.0 2.4 3 0 0 3 3 3 0 Integrase core domain Herpes_BLRF2 PF05812.7 KRH92122.1 - 0.038 13.8 0.2 0.038 13.8 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein AIRC PF00731.15 KRH92122.1 - 0.074 12.3 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AIR carboxylase UFD1 PF03152.9 KRH92125.1 - 1.5e-37 128.3 0.0 1.9e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KRH92125.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 FANCI_S4 PF14678.1 KRH92126.1 - 0.01 14.9 0.2 0.014 14.5 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 MBOAT PF03062.14 KRH92127.1 - 2.8e-12 46.3 2.4 2.8e-12 46.3 1.7 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Peroxin-13_N PF04088.8 KRH92127.1 - 0.0016 18.4 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region MTS PF05175.9 KRH92129.1 - 2.8e-12 46.3 0.0 3.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KRH92129.1 - 1.2e-11 44.3 0.0 1.6e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KRH92129.1 - 5.9e-11 42.4 0.0 7.8e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KRH92129.1 - 4.1e-07 30.2 0.2 8.3e-07 29.3 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KRH92129.1 - 4.7e-07 29.5 0.9 7.7e-07 28.8 0.6 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KRH92129.1 - 7e-06 25.3 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KRH92129.1 - 7.7e-06 26.4 0.0 1.1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KRH92129.1 - 2.3e-05 23.6 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_15 PF09445.5 KRH92129.1 - 5e-05 22.9 0.2 7.5e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 KRH92129.1 - 0.00097 19.5 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KRH92129.1 - 0.0018 17.4 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Spermine_synth PF01564.12 KRH92129.1 - 0.0053 15.7 0.1 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase UPF0020 PF01170.13 KRH92129.1 - 0.0053 16.3 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF43 PF01861.11 KRH92129.1 - 0.0086 15.0 0.2 0.018 14.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF43 Methyltrans_SAM PF10672.4 KRH92129.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase EB1 PF03271.12 KRH92129.1 - 0.024 14.7 1.9 0.029 14.4 0.2 2.0 2 1 0 2 2 2 0 EB1-like C-terminal motif Methyltransf_16 PF10294.4 KRH92129.1 - 0.057 12.8 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TBCC PF07986.7 KRH92130.1 - 9.9e-08 31.4 1.2 9.9e-08 31.4 0.8 2.4 2 1 0 2 2 2 1 Tubulin binding cofactor C mRNA_cap_enzyme PF01331.14 KRH92131.1 - 8.4e-27 94.1 8.1 3.1e-26 92.2 5.6 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 KRH92131.1 - 0.0003 20.1 1.0 0.0047 16.3 0.7 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain KSR1-SAM PF13543.1 KRH92132.1 - 0.0067 16.2 0.0 0.0097 15.7 0.0 1.4 1 1 0 1 1 1 1 SAM like domain present in kinase suppressor RAS 1 PRESAN PF09687.5 KRH92132.1 - 0.031 14.3 0.2 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal RVT_1 PF00078.22 KRH92132.1 - 0.033 13.5 0.2 0.066 12.5 0.2 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AsnA PF03590.10 KRH92132.1 - 0.035 13.5 0.1 0.038 13.4 0.1 1.1 1 0 0 1 1 1 0 Aspartate-ammonia ligase DUF3441 PF11923.3 KRH92134.1 - 6.5e-10 38.6 0.0 1e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3441) Myotub-related PF06602.9 KRH92134.1 - 0.081 11.6 0.1 0.087 11.5 0.1 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Helicase_C PF00271.26 KRH92135.1 - 5.7e-12 45.3 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DDE_Tnp_IS1595 PF12762.2 KRH92137.1 - 3.4e-23 82.1 0.1 4.8e-23 81.6 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.1 KRH92137.1 - 6.6e-06 26.1 2.0 2.8e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 DDE domain DDE_3 PF13358.1 KRH92137.1 - 0.0029 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KRH92138.1 - 7e-05 22.6 0.0 8.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MecA PF05389.7 KRH92138.1 - 0.15 11.5 0.1 0.2 11.1 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) ETRAMP PF09716.5 KRH92139.1 - 0.0024 17.8 3.0 0.36 10.7 0.0 3.4 3 1 0 3 3 3 2 Malarial early transcribed membrane protein (ETRAMP) DUF1510 PF07423.6 KRH92139.1 - 0.0044 16.4 0.5 0.0085 15.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Viral_Beta_CD PF04530.7 KRH92139.1 - 5.4 7.1 10.2 2.5 8.2 0.4 3.6 1 1 3 4 4 4 0 Viral Beta C/D like family LisH PF08513.6 KRH92140.1 - 2.7e-08 33.2 0.3 4.5e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.5 KRH92140.1 - 0.099 12.6 1.0 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 FOP N terminal dimerisation domain DUF357 PF04010.8 KRH92140.1 - 0.39 10.4 0.1 0.39 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) UNC45-central PF11701.3 KRH92141.1 - 0.044 13.4 0.9 0.07 12.7 0.4 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Arv1 PF04161.8 KRH92141.1 - 0.082 12.8 4.1 0.084 12.7 0.6 2.1 1 1 1 2 2 2 0 Arv1-like family DUF4240 PF14024.1 KRH92141.1 - 0.086 12.6 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) TetR_C_8 PF14278.1 KRH92141.1 - 1.3 9.4 7.9 0.45 10.9 2.2 2.6 2 2 0 2 2 2 0 Transcriptional regulator C-terminal region Ribosomal_S28e PF01200.13 KRH92142.1 - 2.7e-16 59.0 0.1 2.8e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e AAA PF00004.24 KRH92143.1 - 3.2e-24 85.5 0.0 1.1e-23 83.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KRH92143.1 - 9.6e-09 35.3 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KRH92143.1 - 2e-05 23.7 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KRH92143.1 - 4.3e-05 24.3 0.0 0.00034 21.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KRH92143.1 - 0.00028 20.4 0.0 0.017 14.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 KRH92143.1 - 0.00095 19.1 0.0 0.0023 17.9 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KRH92143.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KRH92143.1 - 0.0012 18.0 0.0 0.67 9.0 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KRH92143.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 KRH92143.1 - 0.002 18.2 0.3 2.2 8.4 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 KRH92143.1 - 0.0086 15.8 0.0 0.06 13.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KRH92143.1 - 0.01 14.5 0.0 0.02 13.6 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KRH92143.1 - 0.011 15.8 0.0 0.065 13.4 0.0 2.4 2 2 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KRH92143.1 - 0.029 14.2 0.3 0.13 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 KRH92143.1 - 0.1 11.7 0.1 7.6 5.5 0.0 2.7 3 0 0 3 3 3 0 KaiC zf-C2H2_4 PF13894.1 KRH92144.1 - 0.064 13.6 1.1 1.1 9.7 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3216 PF11505.3 KRH92145.1 - 0.049 13.4 1.3 0.68 9.7 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3216) DUF3336 PF11815.3 KRH92145.1 - 0.43 10.0 3.2 0.18 11.3 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) BatD PF13584.1 KRH92146.1 - 2.4 6.6 5.0 0.44 9.0 0.0 2.0 2 0 0 2 2 2 0 Oxygen tolerance Spc97_Spc98 PF04130.8 KRH92147.1 - 2.5e-18 65.7 15.7 3.9e-17 61.7 10.9 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family stn_TNFRSF12A PF12191.3 KRH92147.1 - 0.039 13.9 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain RNA_pol_Rpb1_5 PF04998.12 KRH92148.1 - 4.4e-21 75.3 0.0 5.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R PF05001.8 KRH92148.1 - 1.2e-11 43.7 69.6 0.0028 17.6 2.8 7.9 2 1 10 12 12 12 10 RNA polymerase Rpb1 C-terminal repeat DM13 PF10517.4 KRH92149.1 - 0.091 13.1 0.4 0.31 11.4 0.2 1.9 2 0 0 2 2 2 0 Electron transfer DM13 INCENP_ARK-bind PF03941.10 KRH92149.1 - 0.12 12.2 3.4 0.24 11.2 0.5 2.6 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Lipase_3 PF01764.20 KRH92150.1 - 0.0054 16.3 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KRH92150.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4286 PF14114.1 KRH92150.1 - 0.044 14.0 0.5 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) ACT_7 PF13840.1 KRH92150.1 - 0.045 13.2 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF2305 PF10230.4 KRH92150.1 - 0.066 12.6 0.3 1.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF1514 PF07438.6 KRH92151.1 - 0.13 12.1 1.6 0.35 10.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) UCH PF00443.24 KRH92152.1 - 2.7e-32 111.9 18.2 6.9e-32 110.6 12.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH92152.1 - 1.5e-13 50.8 16.9 5e-11 42.5 11.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MOZ_SAS PF01853.13 KRH92153.1 - 1.5e-60 203.7 5.4 2.7e-60 202.8 3.7 1.4 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 KRH92153.1 - 1.3e-05 25.2 0.1 3.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KRH92153.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KRH92153.1 - 0.043 13.9 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain gp32 PF08804.5 KRH92153.1 - 0.095 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 gp32 DNA binding protein like DUF2582 PF10771.4 KRH92153.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) tRNA-synt_1g PF09334.6 KRH92154.1 - 9.9e-15 54.0 0.0 2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KRH92154.1 - 2.2e-11 42.4 0.2 3.3e-10 38.6 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KRH92154.1 - 8.6e-11 41.4 0.1 1.6e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KRH92154.1 - 0.0022 16.7 0.3 0.01 14.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (K) Acyltransferase PF01553.16 KRH92155.1 - 2.8e-19 68.8 0.1 4.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Orbi_VP5 PF00901.12 KRH92156.1 - 0.071 11.3 6.1 0.091 10.9 4.3 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 NAD_binding_5 PF07994.7 KRH92156.1 - 0.25 10.8 2.9 0.3 10.5 2.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Ycf1 PF05758.7 KRH92156.1 - 0.84 7.2 8.6 0.99 7.0 6.0 1.0 1 0 0 1 1 1 0 Ycf1 CorA PF01544.13 KRH92156.1 - 1.9 7.4 7.5 2.7 6.9 5.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CBF_beta PF02312.12 KRH92156.1 - 2.2 7.8 10.1 0.42 10.2 4.1 1.9 1 1 1 2 2 2 0 Core binding factor beta subunit Atg14 PF10186.4 KRH92156.1 - 5.9 5.7 9.7 7.4 5.4 6.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Arch_ATPase PF01637.13 KRH92157.1 - 3.9e-06 26.7 0.3 4.7e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KRH92157.1 - 0.00022 21.1 0.4 0.00058 19.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH92157.1 - 0.0022 18.0 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 KRH92157.1 - 0.0046 16.9 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KRH92157.1 - 0.0052 16.7 0.4 0.01 15.7 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KRH92157.1 - 0.0095 15.1 0.0 0.014 14.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit T2SE PF00437.15 KRH92157.1 - 0.012 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.13 KRH92157.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 KRH92157.1 - 0.022 15.2 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 Miro-like protein DUF4079 PF13301.1 KRH92157.1 - 0.028 14.4 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) MobB PF03205.9 KRH92157.1 - 0.03 14.0 0.1 0.056 13.1 0.0 1.6 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KRH92157.1 - 0.054 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP-synt_8 PF00895.15 KRH92157.1 - 0.074 13.2 2.6 0.17 12.1 1.8 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 DUF843 PF05814.6 KRH92157.1 - 1 9.1 4.0 0.47 10.2 0.6 2.0 1 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Nodulin_late PF07127.6 KRH92157.1 - 1.9 8.6 7.5 9.4 6.4 0.4 2.3 2 0 0 2 2 2 0 Late nodulin protein Far-17a_AIG1 PF04750.9 KRH92161.1 - 7.6e-13 48.0 13.0 9.4e-13 47.7 9.0 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4435 PF14491.1 KRH92161.1 - 0.02 14.7 1.5 0.031 14.0 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) CBFD_NFYB_HMF PF00808.18 KRH92162.1 - 9.6e-06 25.5 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KRH92162.1 - 5.3e-05 23.2 0.0 6.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KRH92162.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 KRH92162.1 - 0.096 12.4 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Ricin_B_lectin PF00652.17 KRH92163.1 - 0.00098 19.1 0.7 0.0017 18.3 0.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Herpes_LMP1 PF05297.6 KRH92163.1 - 2.6 6.9 8.8 3.7 6.3 6.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RVT_1 PF00078.22 KRH92165.1 - 0.0027 17.0 0.1 0.0033 16.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Eno-Rase_FAD_bd PF07055.7 KRH92167.1 - 0.051 13.5 0.4 0.15 12.0 0.2 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain HSCB_C PF07743.8 KRH92167.1 - 1.5 9.3 7.9 4.3 7.8 3.4 3.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain RVT_1 PF00078.22 KRH92168.1 - 5e-19 68.5 0.2 7.5e-19 67.9 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zw10 PF06248.8 KRH92168.1 - 0.037 12.2 0.3 0.052 11.6 0.2 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 RVT_1 PF00078.22 KRH92169.1 - 0.04 13.2 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SPOUT_MTase PF02590.12 KRH92170.1 - 0.087 12.5 0.4 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase HTH_40 PF14493.1 KRH92170.1 - 0.095 12.9 1.4 0.27 11.4 0.2 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain DUF3038 PF11237.3 KRH92170.1 - 0.33 10.7 3.3 0.81 9.4 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) Retrotrans_gag PF03732.12 KRH92170.1 - 0.54 10.3 6.3 0.85 9.7 2.8 2.3 1 1 0 1 1 1 0 Retrotransposon gag protein Maf1 PF09174.5 KRH92172.1 - 0.0001 22.2 11.7 0.00016 21.5 5.0 2.1 1 1 1 2 2 2 1 Maf1 regulator SLA_LP_auto_ag PF05889.8 KRH92172.1 - 0.13 10.6 0.4 0.16 10.4 0.3 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) YhdB PF14148.1 KRH92172.1 - 2.2 8.0 7.0 12 5.7 0.7 2.7 2 1 1 3 3 3 0 YhdB-like protein Actin PF00022.14 KRH92173.1 - 4.8e-06 25.2 0.0 5.8e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Actin SGS PF05002.10 KRH92173.1 - 0.0019 17.8 0.5 0.0052 16.4 0.1 1.9 2 0 0 2 2 2 1 SGS domain Med23 PF11573.3 KRH92173.1 - 0.18 9.0 2.1 0.19 9.0 1.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 rve PF00665.21 KRH92175.1 - 1.6e-22 79.8 0.1 2.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92175.1 - 5.7e-05 23.1 0.6 0.00012 22.1 0.1 1.8 2 1 1 3 3 3 1 DDE domain rve_3 PF13683.1 KRH92175.1 - 7.4e-05 22.1 0.2 0.0073 15.7 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain SBP_bac_5 PF00496.17 KRH92175.1 - 0.018 13.8 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2312 PF10073.4 KRH92175.1 - 0.043 13.1 1.0 1.6 8.1 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) O-FucT PF10250.4 KRH92175.1 - 0.068 12.2 1.9 0.27 10.2 0.0 2.0 1 1 1 2 2 2 0 GDP-fucose protein O-fucosyltransferase gag_pre-integrs PF13976.1 KRH92180.1 - 0.012 15.1 1.2 0.017 14.7 0.8 1.3 1 0 0 1 1 1 0 GAG-pre-integrase domain Arf PF00025.16 KRH92181.1 - 5.7e-33 113.6 0.1 2.8e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KRH92181.1 - 3.9e-10 38.9 2.2 1.1e-05 24.3 0.1 3.0 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KRH92181.1 - 5.8e-09 35.4 0.0 7.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KRH92181.1 - 1e-07 32.4 0.5 1.5e-05 25.4 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 KRH92181.1 - 3.5e-06 26.5 1.5 0.039 13.3 0.1 3.2 1 1 1 3 3 3 3 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KRH92181.1 - 4.4e-06 26.6 0.0 8.1e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KRH92181.1 - 0.00039 19.6 0.1 0.0012 18.0 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KRH92181.1 - 0.0014 18.0 0.1 0.0046 16.3 0.1 1.9 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.13 KRH92181.1 - 0.013 14.7 0.4 4.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Thymidylate_kin PF02223.12 KRH92181.1 - 0.026 13.9 0.2 0.13 11.5 0.0 2.2 3 0 0 3 3 3 0 Thymidylate kinase PduV-EutP PF10662.4 KRH92181.1 - 0.026 14.0 0.4 0.14 11.6 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF992 PF06186.6 KRH92181.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF992) AAA_33 PF13671.1 KRH92181.1 - 0.14 12.0 0.0 1.7 8.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb2_6 PF00562.23 KRH92182.1 - 3e-58 197.4 4.3 9e-35 120.1 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 rve PF00665.21 KRH92183.1 - 0.0028 17.7 0.1 0.02 15.0 0.0 2.4 3 1 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 KRH92183.1 - 0.0033 17.0 0.1 0.0064 16.1 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 KRH92184.1 - 0.003 16.9 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C4H2 PF10146.4 KRH92185.1 - 0.015 15.3 5.2 0.02 14.8 3.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein TcpE PF12648.2 KRH92185.1 - 1.6 8.8 7.8 2.7 8.1 3.3 2.4 2 1 0 2 2 2 0 TcpE family Thymidylate_kin PF02223.12 KRH92186.1 - 3.3e-31 108.0 0.1 3.8e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase Arch_ATPase PF01637.13 KRH92186.1 - 4.1e-05 23.4 0.9 7.7e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 KRH92186.1 - 0.00012 21.9 0.8 0.00017 21.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KRH92186.1 - 0.00022 21.5 0.7 0.001 19.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KRH92186.1 - 0.0012 19.0 0.0 0.0062 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KRH92186.1 - 0.0013 19.5 0.1 0.0024 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KRH92186.1 - 0.0024 17.8 0.1 0.0031 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KRH92186.1 - 0.0038 16.8 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 KRH92186.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PRK PF00485.13 KRH92186.1 - 0.013 15.0 0.2 0.059 12.9 0.0 1.9 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TIP49 PF06068.8 KRH92186.1 - 0.019 13.6 0.1 0.068 11.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus Arf PF00025.16 KRH92186.1 - 0.033 13.4 0.1 0.09 12.0 0.0 1.7 1 1 1 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.10 KRH92186.1 - 0.036 13.7 0.7 0.076 12.7 0.1 1.8 2 0 0 2 2 2 0 NTPase Guanylate_kin PF00625.16 KRH92186.1 - 0.037 13.4 1.1 0.25 10.7 0.8 2.0 1 1 0 1 1 1 0 Guanylate kinase NACHT PF05729.7 KRH92186.1 - 0.059 13.0 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KRH92186.1 - 0.062 13.2 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KRH92186.1 - 0.066 12.9 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KRH92186.1 - 0.12 12.5 0.2 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase rve PF00665.21 KRH92187.1 - 2.3e-14 53.5 0.1 5.4e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92187.1 - 0.0012 18.8 0.1 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 DDE domain Methyltransf_32 PF13679.1 KRH92187.1 - 0.034 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Plasmid_Txe PF06769.8 KRH92187.1 - 0.076 12.8 0.0 0.3 10.9 0.0 2.0 1 0 0 1 1 1 0 Plasmid encoded toxin Txe Smr PF01713.16 KRH92188.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Smr domain DDE_3 PF13358.1 KRH92189.1 - 5e-08 32.8 0.1 6e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_Rpb2_1 PF04563.10 KRH92189.1 - 0.037 12.9 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit HTH_Tnp_Tc3_2 PF01498.13 KRH92192.1 - 1e-08 35.1 0.1 1.4e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Transposase PNGaseA PF12222.3 KRH92192.1 - 0.082 11.7 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_21 PF13276.1 KRH92192.1 - 0.19 11.7 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 HTH-like domain Nop PF01798.13 KRH92193.1 - 8.7e-36 122.4 1.3 1.6e-35 121.6 0.9 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain CorA PF01544.13 KRH92194.1 - 5e-26 91.4 10.8 8.1e-21 74.3 1.5 2.0 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DUF805 PF05656.9 KRH92194.1 - 0.09 12.6 1.0 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Asp_protease_2 PF13650.1 KRH92195.1 - 2.5e-05 24.7 0.0 3.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92195.1 - 0.0049 16.6 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 KRH92195.1 - 0.031 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Diphthamide_syn PF01866.12 KRH92196.1 - 7.4e-17 61.5 0.3 1.1e-16 61.0 0.2 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein zf-DHHC PF01529.15 KRH92198.1 - 5.7e-29 100.7 13.7 5.6e-29 100.7 9.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase 7tm_7 PF08395.7 KRH92198.1 - 1.8 7.5 20.4 0.12 11.3 5.4 2.1 1 1 1 2 2 2 0 7tm Chemosensory receptor DUF2207 PF09972.4 KRH92198.1 - 9.7 4.6 7.0 1.1 7.7 0.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MIP PF00230.15 KRH92200.1 - 2.1e-31 109.1 14.3 5.2e-31 107.8 9.9 1.6 1 1 0 1 1 1 1 Major intrinsic protein Vpu PF00558.14 KRH92200.1 - 0.63 9.6 3.9 0.95 9.0 0.0 2.7 3 0 0 3 3 3 0 Vpu protein Ribosomal_S8e PF01201.17 KRH92202.1 - 4.5e-42 143.3 4.7 5.5e-42 143.0 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Asn_synthase PF00733.16 KRH92203.1 - 8.1e-21 74.6 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 KRH92203.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 PP-loop family GCS PF03074.11 KRH92204.1 - 1.7e-35 122.8 1.9 3.2e-26 92.2 2.0 2.2 2 0 0 2 2 2 2 Glutamate-cysteine ligase PGK PF00162.14 KRH92205.1 - 1.9e-20 72.7 2.5 2.1e-17 62.7 0.1 2.3 1 1 1 2 2 2 2 Phosphoglycerate kinase Lipoprotein_10 PF03202.8 KRH92205.1 - 1.1 9.2 5.7 0.46 10.5 0.1 2.6 3 0 0 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region DUF2098 PF09871.4 KRH92205.1 - 2 8.4 8.0 2.1 8.3 2.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Asp_protease_2 PF13650.1 KRH92206.1 - 5.2e-05 23.6 0.0 6e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92206.1 - 0.0075 16.0 0.0 0.0091 15.8 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 KRH92206.1 - 0.083 12.2 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase RVP PF00077.15 KRH92206.1 - 0.095 12.6 0.0 0.34 10.8 0.0 1.7 1 1 1 2 2 2 0 Retroviral aspartyl protease zf-C2H2_4 PF13894.1 KRH92210.1 - 0.059 13.7 0.5 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Sec63 PF02889.11 KRH92213.1 - 0.00073 18.8 2.9 0.03 13.5 0.2 2.3 2 1 0 2 2 2 2 Sec63 Brl domain Cut8_C PF08559.5 KRH92213.1 - 0.011 15.5 1.2 0.068 12.9 0.3 2.4 2 1 0 2 2 2 0 Cut8 six-helix bundle DUF2201_N PF13203.1 KRH92213.1 - 0.3 10.2 2.8 0.4 9.8 1.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 KRH92214.1 - 4.8 4.9 20.5 6.4 4.5 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family LSM PF01423.17 KRH92215.1 - 7.1e-05 22.2 0.7 8.9e-05 21.9 0.5 1.1 1 0 0 1 1 1 1 LSM domain KicB PF03882.9 KRH92215.1 - 0.12 10.9 0.1 0.13 10.8 0.1 1.0 1 0 0 1 1 1 0 KicB killing factor DUF365 PF04033.7 KRH92216.1 - 0.022 14.7 2.0 0.058 13.3 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Glyco_tran_28_C PF04101.11 KRH92216.1 - 0.035 13.7 3.4 0.64 9.6 1.1 2.9 2 1 1 3 3 3 0 Glycosyltransferase family 28 C-terminal domain Antimicrobial19 PF08225.6 KRH92216.1 - 1.8 8.0 4.4 27 4.2 0.1 3.2 3 1 0 3 3 3 0 Pseudin antimicrobial peptide DDE_Tnp_IS1595 PF12762.2 KRH92217.1 - 3.5e-28 98.3 0.0 4.8e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH92217.1 - 0.52 9.8 3.2 0.69 9.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Abhydrolase_5 PF12695.2 KRH92218.1 - 2e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KRH92218.1 - 0.0038 16.1 0.1 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.2 KRH92218.1 - 0.0071 16.2 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KRH92218.1 - 0.021 14.5 0.0 0.075 12.7 0.0 2.0 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KRH92218.1 - 0.081 12.3 0.2 2.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase L_lactis_RepB_C PF06430.7 KRH92218.1 - 0.23 11.5 3.2 2.3 8.3 0.1 2.5 3 0 0 3 3 3 0 Lactococcus lactis RepB C-terminus Nse4_C PF08743.5 KRH92219.1 - 9.2e-16 57.6 1.0 2.9e-15 56.0 0.1 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Fimbrillin_C PF15495.1 KRH92219.1 - 0.012 15.7 0.4 0.029 14.5 0.3 1.7 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal RAI1 PF08652.6 KRH92219.1 - 0.2 11.4 1.5 0.98 9.2 0.0 2.8 2 1 1 3 3 3 0 RAI1 like PD-(D/E)XK nuclease RVT_1 PF00078.22 KRH92221.1 - 2.1e-13 50.1 0.1 2.5e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDtoxinA PF03498.9 KRH92224.1 - 0.00022 20.6 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family Curto_V2 PF07325.6 KRH92224.1 - 0.19 11.3 3.7 0.14 11.8 1.2 1.6 2 0 0 2 2 2 0 Curtovirus V2 protein PX PF00787.19 KRH92225.1 - 0.0002 21.1 2.2 0.00043 20.0 1.6 1.6 1 0 0 1 1 1 1 PX domain DUF2247 PF10004.4 KRH92225.1 - 0.39 10.4 8.0 0.055 13.1 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) gag-asp_proteas PF13975.1 KRH92226.1 - 3e-07 30.1 0.0 5.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH92226.1 - 1.6e-06 27.9 1.0 3.5e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 KRH92226.1 - 8.1e-06 25.1 1.3 8.1e-06 25.1 0.9 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 KRH92226.1 - 1.4e-05 25.4 0.1 4e-05 24.0 0.1 1.8 1 1 1 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 KRH92226.1 - 0.00025 20.8 3.7 0.00025 20.8 2.6 1.9 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.6 KRH92226.1 - 0.0054 16.6 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.7 KRH92226.1 - 0.0063 16.0 0.7 0.011 15.3 0.1 1.6 2 0 0 2 2 2 1 Putative peptidase (DUF1758) Asp_protease PF09668.5 KRH92226.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.1 KRH92227.1 - 5.3e-18 65.1 0.3 8.9e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH92227.1 - 2.6e-11 43.3 1.6 3.3e-08 33.4 0.1 2.9 3 0 0 3 3 3 2 Transposase HTH_29 PF13551.1 KRH92227.1 - 0.00013 22.1 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KRH92227.1 - 0.00085 18.8 0.0 0.0035 16.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 KRH92227.1 - 0.0015 19.2 0.2 0.0063 17.2 0.1 2.1 1 1 1 2 2 2 1 Homeodomain-like domain rve PF00665.21 KRH92227.1 - 0.0052 16.8 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_IclR PF09339.5 KRH92227.1 - 0.0056 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.2 KRH92227.1 - 0.0074 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 MarR family LacI PF00356.16 KRH92227.1 - 0.041 13.5 0.1 0.48 10.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.17 KRH92227.1 - 0.041 13.7 0.2 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix TrmB PF01978.14 KRH92227.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 KRH92227.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_19 PF12844.2 KRH92227.1 - 0.061 13.3 0.1 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.1 KRH92227.1 - 0.095 12.1 0.6 2.9 7.3 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Sulfolobus_pRN PF05584.6 KRH92227.1 - 0.18 11.7 0.8 0.59 10.1 0.0 2.1 2 1 0 2 2 2 0 Sulfolobus plasmid regulatory protein zf-met PF12874.2 KRH92228.1 - 2.8e-05 24.1 4.7 5e-05 23.3 3.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KRH92228.1 - 0.00035 20.6 0.7 0.0006 19.8 0.5 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KRH92228.1 - 0.021 14.9 5.5 0.04 14.0 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1460 PF07313.7 KRH92228.1 - 0.031 13.4 0.9 0.04 13.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Mu-like_Com PF10122.4 KRH92228.1 - 0.075 12.1 0.0 14 4.8 0.1 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com RNA_pol_Rpb2_7 PF04560.15 KRH92230.1 - 5.3e-23 81.0 0.1 1.9e-22 79.2 0.1 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_6 PF00562.23 KRH92230.1 - 8e-20 70.9 0.1 1.1e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Pentapeptide_2 PF01469.13 KRH92230.1 - 7.3e-06 25.5 5.5 1.1e-05 24.9 3.8 1.3 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) MDFI PF15316.1 KRH92230.1 - 0.0076 16.2 0.1 0.022 14.7 0.0 1.6 1 1 0 2 2 2 1 MyoD family inhibitor NTP_transferase PF00483.18 KRH92231.1 - 0.027 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase DUF1890 PF09001.6 KRH92231.1 - 0.078 12.9 0.2 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1890) Peptidase_C97 PF05903.9 KRH92232.1 - 1.3e-35 122.4 0.7 1.4e-35 122.2 0.5 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KRH92232.1 - 0.013 15.4 0.3 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF778 PF05608.7 KRH92232.1 - 0.048 13.6 0.1 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) PGAP1 PF07819.8 KRH92234.1 - 0.13 11.8 0.1 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DDE_3 PF13358.1 KRH92235.1 - 9.1e-09 35.2 0.1 1e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MS_channel PF00924.13 KRH92236.1 - 2.2e-16 59.8 3.1 3.2e-16 59.2 2.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KRH92236.1 - 0.003 16.7 0.3 0.003 16.7 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KRH92236.1 - 0.009 15.6 0.2 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF2207 PF09972.4 KRH92236.1 - 0.01 14.4 2.4 0.018 13.6 1.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EF-hand_6 PF13405.1 KRH92236.1 - 0.033 14.0 4.9 0.038 13.8 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 KRH92236.1 - 3.3 7.2 6.0 0.44 9.9 0.4 2.3 2 0 0 2 2 2 0 EF hand AMP-binding_C PF13193.1 KRH92237.1 - 5.6e-15 56.0 0.0 8.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-RING_2 PF13639.1 KRH92238.1 - 5.7e-11 42.0 1.8 9.8e-11 41.3 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KRH92238.1 - 2.6e-10 40.2 0.7 4.1e-10 39.6 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KRH92238.1 - 1.3e-06 28.0 0.5 2.3e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KRH92238.1 - 4.8e-06 26.1 0.8 7.5e-06 25.5 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH92238.1 - 4.9e-06 26.0 0.5 9.8e-06 25.1 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH92238.1 - 6.6e-06 26.0 1.1 1.1e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KRH92238.1 - 6.6e-06 25.8 1.1 1e-05 25.2 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KRH92238.1 - 0.0033 17.2 1.9 0.0086 15.9 1.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KRH92238.1 - 0.0048 16.4 1.7 0.013 15.0 1.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KRH92238.1 - 0.026 14.2 5.7 0.073 12.7 2.1 2.8 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.6 KRH92238.1 - 0.065 13.2 3.7 0.12 12.3 2.6 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 KRH92238.1 - 0.19 11.8 4.4 0.41 10.7 3.0 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KRH92238.1 - 0.88 9.5 5.2 4.9 7.1 3.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KRH92238.1 - 0.9 9.2 4.3 3 7.6 2.9 1.9 1 1 0 1 1 1 0 PHD-finger Hid1 PF12722.2 KRH92238.1 - 4.9 4.7 13.7 5.2 4.6 9.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-B_box PF00643.19 KRH92239.1 - 1.7e-12 46.9 19.9 1e-06 28.5 5.1 2.3 2 0 0 2 2 2 2 B-box zinc finger Cloacin_immun PF03513.9 KRH92239.1 - 0.2 11.7 4.1 1 9.4 0.2 3.0 2 1 0 2 2 2 0 Cloacin immunity protein zf-FPG_IleRS PF06827.9 KRH92239.1 - 0.57 9.8 5.7 4.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-UBR PF02207.15 KRH92239.1 - 3.7 7.3 19.9 0.55 9.9 4.3 3.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DEAD PF00270.24 KRH92241.1 - 1.3e-06 27.9 0.2 1.9e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 KRH92241.1 - 0.086 12.0 0.1 0.26 10.5 0.0 1.7 1 1 1 2 2 2 0 PhoH-like protein Coronavirus_5 PF05528.6 KRH92242.1 - 0.0092 15.7 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Coronavirus gene 5 protein Dala_Dala_lig_N PF01820.16 KRH92242.1 - 1.1 9.5 3.3 1.4 9.2 2.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF1980 PF09323.5 KRH92242.1 - 7.8 6.2 7.0 12 5.5 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) XPG_N PF00752.12 KRH92243.1 - 6e-10 39.2 0.0 3.1e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain zf-C3HC4_3 PF13920.1 KRH92243.1 - 0.043 13.4 0.5 0.091 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) APS_kinase PF01583.15 KRH92243.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SBDS PF01172.13 KRH92244.1 - 0.023 14.4 2.5 0.03 14.1 1.8 1.2 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Dala_Dala_lig_N PF01820.16 KRH92244.1 - 0.53 10.6 4.3 0.68 10.2 3.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus XPG_N PF00752.12 KRH92245.1 - 8.4e-10 38.8 0.0 4.2e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 XPG N-terminal domain zf-C3HC4_3 PF13920.1 KRH92245.1 - 0.043 13.4 0.5 0.091 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) APS_kinase PF01583.15 KRH92245.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase RVT_1 PF00078.22 KRH92246.1 - 4.4e-09 36.0 0.2 8.6e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.18 KRH92247.1 - 3.9e-18 65.4 1.9 2.1e-14 53.4 0.1 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase NGP1NT PF08153.7 KRH92247.1 - 3.2e-12 46.5 1.7 5.7e-12 45.7 1.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain FeoB_N PF02421.13 KRH92247.1 - 9.1e-09 34.7 0.7 0.0002 20.6 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KRH92247.1 - 3.9e-05 23.1 0.4 0.0083 15.5 0.0 3.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KRH92247.1 - 0.00065 18.9 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KRH92247.1 - 0.00087 19.7 2.3 1.1 9.7 0.0 3.2 2 1 1 3 3 3 1 Miro-like protein DUF2375 PF09558.5 KRH92247.1 - 0.0033 17.2 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2375) Arf PF00025.16 KRH92247.1 - 0.0034 16.6 0.3 0.63 9.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.14 KRH92247.1 - 0.007 15.8 0.2 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 KRH92247.1 - 0.016 14.3 3.6 0.61 9.1 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KRH92247.1 - 0.017 14.7 0.5 0.055 13.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KRH92247.1 - 0.11 11.1 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 KRH92247.1 - 0.15 11.1 2.6 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.18 KRH92247.1 - 0.39 10.5 7.1 3.4 7.4 0.1 3.7 2 2 1 3 3 3 0 Dynamin family Proteasome PF00227.21 KRH92248.1 - 2.6e-30 105.1 0.0 3.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KRH92248.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature EpsG PF14897.1 KRH92249.1 - 0.13 11.1 2.9 0.13 11.1 2.0 1.0 1 0 0 1 1 1 0 EpsG family DNA_photolyase PF00875.13 KRH92250.1 - 4.8e-08 32.9 0.1 2.7e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 DNA photolyase DUF4220 PF13968.1 KRH92250.1 - 0.51 9.3 5.9 0.77 8.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Flu_B_M2 PF04772.7 KRH92250.1 - 0.9 9.6 4.1 0.29 11.2 0.3 2.0 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) FerA PF08165.6 KRH92251.1 - 0.016 14.8 1.0 0.091 12.4 0.1 2.5 2 0 0 2 2 2 0 FerA (NUC095) domain hDGE_amylase PF14701.1 KRH92251.1 - 0.29 10.0 5.1 0.35 9.7 3.5 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme NPHI_C PF08469.5 KRH92251.1 - 0.88 9.4 10.7 0.36 10.7 3.8 2.0 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal PP2C_C PF07830.8 KRH92251.1 - 1.6 8.8 6.7 0.64 10.1 0.9 2.8 3 1 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain HTH_40 PF14493.1 KRH92251.1 - 2.8 8.2 6.9 1.8 8.8 0.1 2.9 1 1 1 2 2 2 0 Helix-turn-helix domain DUF3660 PF12398.3 KRH92252.1 - 5.1 7.0 12.0 26 4.7 0.5 5.1 4 2 2 6 6 6 0 Receptor serine/threonine kinase RicinB_lectin_2 PF14200.1 KRH92254.1 - 4e-07 30.3 0.2 0.0006 20.1 0.0 1.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KRH92254.1 - 1.5e-05 24.9 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain SET_assoc PF11767.3 KRH92254.1 - 0.0011 18.2 0.8 0.004 16.4 0.0 2.3 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated TRM PF02005.11 KRH92255.1 - 2.6e-65 220.8 0.6 3.3e-65 220.4 0.4 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Gemini_AL2 PF01440.11 KRH92255.1 - 0.028 14.5 1.0 0.05 13.6 0.7 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein MarR PF01047.17 KRH92255.1 - 0.062 13.0 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 MarR family rve PF00665.21 KRH92258.1 - 2e-22 79.5 0.0 3.2e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92258.1 - 0.0002 20.8 0.3 0.0035 16.8 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92258.1 - 0.00029 20.8 0.2 0.0006 19.8 0.1 1.6 1 0 0 1 1 1 1 DDE domain SBP_bac_5 PF00496.17 KRH92258.1 - 0.028 13.2 0.7 0.043 12.6 0.5 1.5 1 1 1 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle RVT_1 PF00078.22 KRH92259.1 - 2.6e-09 36.7 0.2 4.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH92260.1 - 2.6e-09 36.7 0.2 4.9e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NTP_transf_2 PF01909.18 KRH92261.1 - 8.2e-10 38.8 0.1 2.4e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 KRH92261.1 - 0.00073 18.4 4.5 0.0011 17.8 3.1 1.4 1 1 0 1 1 1 1 Poly(A) polymerase central domain DNA_pol_B_palm PF14792.1 KRH92261.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Pkinase PF00069.20 KRH92262.1 - 3.8e-62 209.7 0.1 4.4e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92262.1 - 1.9e-36 125.4 0.0 2.7e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KRH92262.1 - 0.00092 19.0 0.0 0.0062 16.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KRH92262.1 - 0.0036 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KRH92262.1 - 0.0064 15.4 0.0 0.0096 14.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KRH92262.1 - 0.023 14.0 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL rve PF00665.21 KRH92264.1 - 1.6e-24 86.2 0.0 3.5e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH92264.1 - 0.00084 18.6 2.6 0.00084 18.6 1.8 2.9 3 0 0 3 3 3 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 KRH92264.1 - 0.027 14.0 0.2 0.11 12.0 0.0 2.1 3 0 0 3 3 3 0 Integrase core domain AIRC PF00731.15 KRH92264.1 - 0.093 12.0 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 AIR carboxylase Z1 PF10593.4 KRH92264.1 - 0.47 9.6 4.7 3.6 6.7 1.0 2.3 2 0 0 2 2 2 0 Z1 domain Herpes_BLRF2 PF05812.7 KRH92264.1 - 1 9.1 4.0 0.53 10.1 0.8 2.1 2 2 0 2 2 2 0 Herpesvirus BLRF2 protein Ribosomal_L2_C PF03947.13 KRH92265.1 - 8.6e-42 142.0 0.3 1.5e-41 141.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KRH92265.1 - 2.5e-09 36.9 1.1 1e-08 34.9 0.3 2.3 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain Spc97_Spc98 PF04130.8 KRH92267.1 - 9.3e-20 70.4 7.9 1.3e-19 69.9 5.5 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family ABC2_membrane PF01061.19 KRH92270.1 - 4e-05 22.8 21.8 6e-05 22.2 15.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane PF01061.19 KRH92271.1 - 1.7e-05 24.0 22.7 2.3e-05 23.6 15.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter Helicase_C PF00271.26 KRH92272.1 - 1.3e-22 79.4 0.0 3.4e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KRH92272.1 - 9.3e-21 74.0 0.1 1.8e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 KRH92272.1 - 0.00037 19.6 0.0 0.00062 18.9 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 KRH92272.1 - 0.0017 18.2 1.5 0.0031 17.3 1.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2268 PF10026.4 KRH92272.1 - 0.1 11.9 0.3 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) zf-DBF PF07535.7 KRH92273.1 - 2.2e-17 62.4 2.2 4.1e-17 61.5 1.5 1.4 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 KRH92273.1 - 0.036 13.8 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Dfp1/Him1, central region Ank_2 PF12796.2 KRH92274.1 - 5.2e-12 45.9 0.3 3.9e-10 39.9 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KRH92274.1 - 3.4e-10 39.2 3.0 1.4e-05 24.6 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KRH92274.1 - 4.2e-08 32.6 1.2 0.016 15.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KRH92274.1 - 1.9e-07 31.0 0.8 1.8e-06 28.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KRH92274.1 - 8e-06 26.2 0.7 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Toxin_55 PF15606.1 KRH92274.1 - 1.4 8.9 6.6 3.4 7.7 4.6 1.6 1 0 0 1 1 1 0 Putative toxin 55 Pkinase PF00069.20 KRH92275.1 - 2.4e-53 180.9 1.4 3.4e-53 180.4 1.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92275.1 - 4.2e-31 107.9 0.0 6.7e-31 107.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KRH92275.1 - 0.0003 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KRH92275.1 - 0.004 16.2 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KRH92275.1 - 0.0071 15.9 1.1 0.012 15.2 0.7 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KRH92275.1 - 0.071 12.4 0.2 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RNase_H PF00075.19 KRH92276.1 - 0.0052 17.1 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 RNase H RVT_thumb PF06817.9 KRH92276.1 - 0.0076 15.8 1.2 0.037 13.6 0.0 2.7 2 0 0 2 2 2 1 Reverse transcriptase thumb domain TP6A_N PF04406.9 KRH92277.1 - 5.3e-10 38.8 0.7 5.3e-10 38.8 0.5 2.1 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2220 PF09983.4 KRH92277.1 - 1.3e-05 24.4 0.1 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2399 PF09664.5 KRH92277.1 - 0.048 13.5 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Asp_protease_2 PF13650.1 KRH92278.1 - 2.5e-07 31.0 0.0 4.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH92278.1 - 6.4e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 KRH92278.1 - 0.00045 20.1 0.1 0.00086 19.2 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 KRH92278.1 - 0.00078 18.8 0.3 0.00078 18.8 0.2 1.7 1 1 0 2 2 2 1 Ty3 transposon peptidase rve PF00665.21 KRH92279.1 - 4.1e-29 101.1 0.0 8.6e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Poxvirus_B22R_N PF13169.1 KRH92279.1 - 0.0041 17.2 0.2 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 Poxvirus B22R protein N-terminal DUF2202 PF09968.4 KRH92279.1 - 0.019 14.6 0.1 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) DDE_Tnp_IS1595 PF12762.2 KRH92279.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 ISXO2-like transposase domain Gp58 PF07902.6 KRH92279.1 - 0.034 12.3 0.0 0.045 11.9 0.0 1.2 1 0 0 1 1 1 0 gp58-like protein rve_3 PF13683.1 KRH92279.1 - 0.041 13.4 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain AKAP28 PF14469.1 KRH92279.1 - 0.047 13.2 0.2 0.92 9.0 0.0 2.8 2 1 1 3 3 3 0 28 kDa A-kinase anchor eIF-5_eIF-2B PF01873.12 KRH92279.1 - 0.053 13.1 0.5 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 WD40 PF00400.27 KRH92280.1 - 2.1e-12 46.4 5.7 6.6e-06 25.8 0.0 4.0 3 1 0 3 3 3 3 WD domain, G-beta repeat DUF2072 PF09845.4 KRH92280.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Tyr_Deacylase PF02580.11 KRH92281.1 - 4.9e-10 39.5 0.0 5.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase YojJ PF10372.4 KRH92281.1 - 0.1 12.5 0.2 0.3 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus PGK PF00162.14 KRH92282.1 - 1.1e-20 73.6 0.0 1.2e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PRK PF00485.13 KRH92284.1 - 3.7e-15 55.9 0.3 5e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KRH92284.1 - 1.5e-07 32.2 0.0 5.5e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KRH92284.1 - 2.2e-05 24.3 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 KRH92284.1 - 0.00038 20.1 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KRH92284.1 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KRH92284.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH92284.1 - 0.006 16.5 0.0 0.0082 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KRH92284.1 - 0.0076 15.4 0.1 0.015 14.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 KRH92284.1 - 0.0077 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KRH92284.1 - 0.0098 16.0 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KRH92284.1 - 0.047 13.8 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase dNK PF01712.14 KRH92284.1 - 0.049 13.5 0.5 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase APS_kinase PF01583.15 KRH92284.1 - 0.053 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 KRH92284.1 - 0.065 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.18 KRH92284.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Guanylate_kin PF00625.16 KRH92284.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.7 KRH92284.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.4 1 1 0 1 1 1 0 Zeta toxin Fer4_NifH PF00142.13 KRH92284.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ClpS PF02617.12 KRH92285.1 - 0.056 13.1 0.0 0.069 12.8 0.0 1.2 1 1 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Kri1_C PF12936.2 KRH92285.1 - 0.088 12.7 0.1 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 KRI1-like family C-terminal ATP-cone PF03477.11 KRH92286.1 - 0.019 15.3 0.0 0.026 14.9 0.0 1.4 1 1 0 1 1 1 0 ATP cone domain gag-asp_proteas PF13975.1 KRH92287.1 - 7.1e-08 32.1 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH92287.1 - 3.8e-06 26.7 0.2 6.8e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92287.1 - 2.6e-05 24.6 0.1 5.2e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 KRH92287.1 - 0.00016 21.4 4.5 0.00029 20.5 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 KRH92287.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH92287.1 - 0.00091 18.7 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 KRH92287.1 - 0.0036 16.8 0.1 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A2B PF12384.3 KRH92287.1 - 0.0073 15.6 0.2 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Ty3 transposon peptidase Peptidase_A2E PF12382.3 KRH92287.1 - 0.044 13.5 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase zf-CCHC_4 PF14392.1 KRH92287.1 - 0.72 9.5 4.1 1.6 8.4 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle ATP-cone PF03477.11 KRH92288.1 - 0.0029 17.9 0.1 0.0035 17.7 0.0 1.3 1 1 0 1 1 1 1 ATP cone domain PWI PF01480.12 KRH92289.1 - 0.0076 16.3 3.0 0.0078 16.2 0.3 2.4 2 0 0 2 2 2 1 PWI domain YolD PF08863.5 KRH92289.1 - 0.071 12.9 9.7 0.077 12.8 0.7 2.9 2 0 0 2 2 2 0 YolD-like protein DUF3336 PF11815.3 KRH92290.1 - 0.043 13.3 0.5 0.074 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) TFIIF_alpha PF05793.7 KRH92292.1 - 0.00021 19.8 24.5 0.00021 19.8 17.0 2.9 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Gar1 PF04410.9 KRH92293.1 - 0.017 14.5 2.2 0.036 13.5 1.6 1.7 1 1 0 1 1 1 0 Gar1/Naf1 RNA binding region Sulfate_transp PF00916.15 KRH92295.1 - 0.00012 21.2 0.4 0.00021 20.4 0.3 1.4 1 0 0 1 1 1 1 Sulfate transporter family CarbpepA_inh PF02977.10 KRH92296.1 - 0.097 12.2 2.1 0.18 11.4 1.5 1.5 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor DUF2296 PF10058.4 KRH92297.1 - 2.8e-08 33.3 0.8 5.1e-08 32.5 0.6 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Pex24p PF06398.6 KRH92297.1 - 0.0043 15.9 1.0 0.0067 15.2 0.7 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SPC25 PF06703.6 KRH92297.1 - 0.018 14.6 1.4 0.028 13.9 1.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4220 PF13968.1 KRH92297.1 - 0.052 12.6 0.3 0.075 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) zinc_ribbon_6 PF14599.1 KRH92297.1 - 0.088 12.6 0.4 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon Gly_radical PF01228.16 KRH92297.1 - 0.18 12.1 1.1 0.38 11.1 0.4 1.8 1 1 1 2 2 2 0 Glycine radical WD40 PF00400.27 KRH92298.1 - 3e-30 102.9 0.8 1.7e-07 30.8 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KRH92298.1 - 4.5e-26 90.5 1.8 4.8e-26 90.4 0.2 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex YmzC PF14157.1 KRH92298.1 - 0.041 13.6 0.4 0.36 10.6 0.0 2.4 2 0 0 2 2 2 0 YmzC-like protein RRM_2 PF04059.7 KRH92299.1 - 1.3e-34 118.0 4.9 1.3e-34 118.0 3.4 2.2 3 0 0 3 3 3 1 RNA recognition motif 2 RRM_1 PF00076.17 KRH92299.1 - 0.062 12.9 0.2 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92299.1 - 0.078 12.9 0.1 0.25 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) E2F_TDP PF02319.15 KRH92301.1 - 4.7e-09 35.6 2.3 4.7e-09 35.6 1.6 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.5 KRH92301.1 - 2.5e-08 33.7 4.2 2.5e-08 33.7 2.9 1.5 2 0 0 2 2 2 1 Transcription factor DP TrmB PF01978.14 KRH92301.1 - 0.0032 17.1 0.2 0.0083 15.8 0.2 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Myb_DNA-binding PF00249.26 KRH92302.1 - 2.7e-24 84.9 5.3 3.4e-14 52.6 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KRH92302.1 - 7.1e-19 67.6 10.0 9.4e-11 41.6 0.9 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain HC2 PF07382.6 KRH92302.1 - 0.0078 16.0 0.2 0.011 15.6 0.2 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF4424 PF14415.1 KRH92303.1 - 0.088 12.2 0.1 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) tRNA_anti-codon PF01336.20 KRH92304.1 - 2.8e-13 49.4 0.0 4.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 KRH92304.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3513 PF12026.3 KRH92305.1 - 0.069 12.6 1.4 0.13 11.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) rve PF00665.21 KRH92306.1 - 3.9e-22 78.6 0.0 7.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92306.1 - 6.7e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92306.1 - 0.0007 19.5 0.4 0.0012 18.7 0.3 1.4 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.1 KRH92306.1 - 0.0019 17.9 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease M-inducer_phosp PF06617.8 KRH92307.1 - 0.12 11.3 0.2 0.14 11.2 0.1 1.0 1 0 0 1 1 1 0 M-phase inducer phosphatase Mre11_DNA_bind PF04152.9 KRH92308.1 - 5.9e-16 58.8 10.2 9.7e-15 54.8 3.2 3.4 1 1 1 2 2 2 1 Mre11 DNA-binding presumed domain Dpoe2NT PF12213.3 KRH92308.1 - 0.18 11.7 3.2 4.2 7.3 0.6 2.6 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal EF-hand_3 PF09069.6 KRH92308.1 - 0.19 11.8 1.2 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 EF-hand HECT_2 PF09814.4 KRH92309.1 - 4e-06 25.7 3.1 6.8e-06 25.0 2.1 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding KMP11 PF03037.11 KRH92309.1 - 0.44 11.1 6.2 1.8 9.2 4.3 2.1 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 HAD_2 PF13419.1 KRH92310.1 - 5.5e-16 59.2 0.2 3.9e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KRH92310.1 - 9.2e-06 25.3 3.0 0.0038 16.8 0.2 2.7 2 1 1 3 3 3 2 Acid Phosphatase Hydrolase_like PF13242.1 KRH92310.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PSD4 PF07631.6 KRH92310.1 - 0.031 14.6 0.3 0.15 12.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) PAP_RNA-bind PF04926.10 KRH92313.1 - 0.11 11.9 1.9 0.12 11.8 1.3 1.1 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain DUF3236 PF11576.3 KRH92314.1 - 0.031 13.6 3.1 0.047 13.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) PRA1 PF03208.14 KRH92315.1 - 1.6e-14 53.4 7.0 2.1e-14 53.1 4.8 1.0 1 0 0 1 1 1 1 PRA1 family protein TMPIT PF07851.8 KRH92315.1 - 0.023 13.7 8.3 0.035 13.1 5.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2101 PF09874.4 KRH92315.1 - 0.72 9.3 8.6 0.87 9.0 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Ndc80_HEC PF03801.8 KRH92318.1 - 2.2e-17 62.9 2.9 1.1e-16 60.6 2.0 2.0 1 1 0 1 1 1 1 HEC/Ndc80p family DUF3942 PF13078.1 KRH92318.1 - 0.12 12.4 1.3 0.16 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) Man-6-P_recep PF02157.10 KRH92319.1 - 0.084 11.8 0.1 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DDE_Tnp_IS1595 PF12762.2 KRH92320.1 - 3.8e-21 75.5 0.1 4.5e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Apc3 PF12895.2 KRH92321.1 - 0.0084 16.2 0.6 0.025 14.6 0.4 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KRH92321.1 - 0.12 12.6 0.5 1.8 8.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KRH92321.1 - 0.13 13.0 1.2 7.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KRH92321.1 - 0.35 10.8 5.0 0.81 9.7 0.1 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat CobT PF06213.7 KRH92321.1 - 4.9 6.1 9.5 9.2 5.3 6.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DltD_M PF04918.7 KRH92322.1 - 1.5 8.9 9.3 0.067 13.3 1.4 2.4 3 0 0 3 3 3 0 DltD central region rve PF00665.21 KRH92323.1 - 9.1e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92323.1 - 0.0023 17.3 0.0 0.0098 15.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Septin PF00735.13 KRH92325.1 - 5.5e-65 219.1 0.4 6.6e-65 218.9 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KRH92325.1 - 7.8e-07 29.0 0.2 3.3e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KRH92325.1 - 1.1e-06 29.1 0.6 3.6e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein AIG1 PF04548.11 KRH92325.1 - 3e-05 23.2 0.5 8.7e-05 21.7 0.1 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 KRH92325.1 - 0.0002 21.2 3.0 0.083 12.7 0.2 3.2 1 1 0 2 2 2 2 Dynamin family DUF258 PF03193.11 KRH92325.1 - 0.0002 20.6 0.1 0.00041 19.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KRH92325.1 - 0.0023 17.8 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 KRH92325.1 - 0.0042 16.5 0.3 2.6 7.4 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF520 PF04461.8 KRH92325.1 - 0.0046 16.8 0.4 0.0091 15.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF520) AAA_14 PF13173.1 KRH92325.1 - 0.0059 16.5 0.4 0.052 13.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KRH92325.1 - 0.0074 16.4 0.1 0.028 14.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain Gtr1_RagA PF04670.7 KRH92325.1 - 0.011 14.9 3.2 0.096 11.8 1.6 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KRH92325.1 - 0.012 14.9 0.6 0.073 12.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.17 KRH92325.1 - 0.016 14.5 1.0 0.039 13.3 0.1 1.9 2 0 0 2 2 2 0 Ras family cobW PF02492.14 KRH92325.1 - 0.02 14.3 0.2 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KRH92325.1 - 0.032 13.5 0.1 0.077 12.2 0.1 1.7 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 KRH92325.1 - 0.033 13.7 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KRH92325.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 KRH92325.1 - 0.04 13.1 0.8 0.47 9.6 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 KRH92325.1 - 0.045 13.2 0.2 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KRH92325.1 - 0.059 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KRH92325.1 - 0.059 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KRH92325.1 - 0.068 12.6 0.7 0.56 9.6 0.0 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KRH92325.1 - 0.075 12.4 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain Far-17a_AIG1 PF04750.9 KRH92326.1 - 8.8e-07 28.2 2.1 1e-06 28.0 1.5 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4199 PF13858.1 KRH92326.1 - 0.017 15.0 1.1 2.9 7.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Myb_DNA-binding PF00249.26 KRH92327.1 - 2.6e-24 85.0 5.3 3.5e-14 52.5 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KRH92327.1 - 7.7e-19 67.5 10.0 9.7e-11 41.6 0.9 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain HC2 PF07382.6 KRH92327.1 - 0.015 15.1 1.1 0.021 14.6 0.8 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Ribosomal_S7e PF01251.13 KRH92328.1 - 1.1e-08 34.7 2.9 0.0016 17.9 1.4 2.0 1 1 1 2 2 2 2 Ribosomal protein S7e UQ_con PF00179.21 KRH92330.1 - 1.3e-37 128.3 0.3 1.5e-37 128.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KRH92330.1 - 0.0014 18.4 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KRH92330.1 - 0.02 14.7 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain LSM PF01423.17 KRH92331.1 - 1.2e-08 34.3 1.8 1.8e-08 33.7 1.3 1.3 1 1 0 1 1 1 1 LSM domain 14-3-3 PF00244.15 KRH92332.1 - 2.7e-72 242.6 6.3 3.6e-72 242.2 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1572 PF07609.6 KRH92332.1 - 0.057 12.9 0.1 0.15 11.5 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1572) Nup35_RRM PF05172.8 KRH92336.1 - 0.0056 16.3 1.8 0.27 10.9 1.3 2.4 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ras PF00071.17 KRH92337.1 - 1.4e-42 144.8 0.2 1.8e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KRH92337.1 - 3.4e-18 65.4 0.2 4.8e-18 65.0 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KRH92337.1 - 5.4e-17 62.3 0.0 1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KRH92337.1 - 5.7e-08 32.1 0.0 7.5e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KRH92337.1 - 7.5e-07 28.5 0.1 9.3e-07 28.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KRH92337.1 - 0.00025 20.5 2.2 0.0024 17.3 1.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.7 KRH92337.1 - 0.0016 17.7 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein G-alpha PF00503.15 KRH92337.1 - 0.0037 15.9 4.3 0.014 14.0 0.1 2.7 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.12 KRH92337.1 - 0.012 15.1 2.0 0.48 9.9 0.1 2.7 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KRH92337.1 - 0.019 15.0 0.1 0.059 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KRH92337.1 - 0.02 14.3 1.6 0.18 11.2 1.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KRH92337.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KRH92337.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 KRH92337.1 - 0.13 11.7 1.5 0.27 10.7 0.1 2.1 2 1 1 3 3 3 0 AAA domain GCS PF03074.11 KRH92338.1 - 3.4e-07 29.6 0.0 6.8e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase CNH PF00780.17 KRH92339.1 - 2e-13 50.3 0.8 1.1e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 CNH domain Sec62 PF03839.11 KRH92339.1 - 0.0089 15.4 1.6 0.015 14.7 1.1 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 TLP-20 PF06088.6 KRH92339.1 - 1.9 8.1 11.0 3 7.4 7.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DDE_Tnp_IS1595 PF12762.2 KRH92341.1 - 0.012 15.4 0.2 0.015 15.1 0.2 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain Pho88 PF10032.4 KRH92342.1 - 4.4e-23 81.4 6.6 4.4e-23 81.4 4.6 1.4 1 1 0 1 1 1 1 Phosphate transport (Pho88) DUF2149 PF09919.4 KRH92342.1 - 0.95 9.5 5.9 13 5.9 0.6 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2149) USP7_ICP0_bdg PF12436.3 KRH92343.1 - 0.046 12.9 0.0 0.046 12.9 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 SNase PF00565.12 KRH92344.1 - 2.1e-17 63.3 0.0 1.3e-15 57.6 0.0 2.2 1 1 0 1 1 1 1 Staphylococcal nuclease homologue ATP-synt_8 PF00895.15 KRH92344.1 - 0.015 15.5 1.2 0.04 14.1 0.8 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 TraP PF07296.6 KRH92344.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.8 3 0 0 3 3 3 0 TraP protein Colicin_V PF02674.11 KRH92344.1 - 0.036 13.9 1.1 0.061 13.1 0.8 1.3 1 0 0 1 1 1 0 Colicin V production protein NS3_envE PF02723.9 KRH92344.1 - 0.3 11.0 6.8 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E DUF3902 PF13042.1 KRH92344.1 - 1.4 8.1 8.6 14 4.9 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3902) YMF19 PF02326.10 KRH92344.1 - 5.1 7.7 7.4 1.3 9.6 1.2 2.5 3 0 0 3 3 3 0 Plant ATP synthase F0 Ribosomal_S11 PF00411.14 KRH92345.1 - 3.9e-31 107.4 0.7 5e-31 107.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF4116 PF13475.1 KRH92346.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4116) DUF3890 PF13029.1 KRH92346.1 - 0.016 15.2 0.7 0.03 14.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) CcdB PF01845.12 KRH92346.1 - 0.022 14.6 0.3 0.11 12.4 0.1 1.9 1 1 0 2 2 2 0 CcdB protein BBP1_C PF15272.1 KRH92346.1 - 0.035 13.6 0.3 0.047 13.2 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DDE_Tnp_IS1595 PF12762.2 KRH92347.1 - 2.5e-25 89.0 0.1 1e-24 87.0 0.1 1.9 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_3 PF13358.1 KRH92347.1 - 2.6e-05 24.0 0.0 5.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.1 KRH92347.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 2.4 3 0 0 3 3 3 1 DDE domain zf-BED PF02892.10 KRH92347.1 - 0.17 11.7 3.2 13 5.6 0.1 3.3 3 0 0 3 3 3 0 BED zinc finger DDE_Tnp_IS1595 PF12762.2 KRH92348.1 - 6.7e-24 84.4 0.1 1e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 KRH92348.1 - 8e-06 25.2 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family AlcCBM31 PF11606.3 KRH92348.1 - 0.025 14.5 0.2 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein ATP-grasp_2 PF08442.5 KRH92348.1 - 0.06 12.7 0.7 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 ATP-grasp domain PH PF00169.24 KRH92349.1 - 3.5e-06 27.1 2.2 3.5e-06 27.1 1.5 2.2 2 0 0 2 2 2 1 PH domain DUF2496 PF10689.4 KRH92349.1 - 0.0096 15.4 0.3 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2496) CHIPS PF11434.3 KRH92349.1 - 7.1 6.3 8.9 2.5 7.7 1.7 3.1 3 1 0 3 3 3 0 Chemotaxis-inhibiting protein CHIPS DUF1232 PF06803.7 KRH92350.1 - 0.1 12.0 0.8 0.15 11.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) zf-C2H2 PF00096.21 KRH92351.1 - 3.3e-09 36.5 17.4 8.2e-06 25.8 2.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KRH92351.1 - 7.7e-09 35.4 11.3 4.4e-08 33.0 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KRH92351.1 - 0.00015 21.8 12.7 0.00027 21.0 0.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KRH92351.1 - 0.0098 15.7 0.5 0.0098 15.7 0.4 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger PyrI_C PF02748.10 KRH92351.1 - 0.025 14.0 0.2 0.055 12.9 0.2 1.6 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 KRH92351.1 - 0.04 14.0 12.1 0.061 13.4 1.1 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KRH92351.1 - 0.32 11.2 0.4 0.32 11.2 0.3 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KRH92351.1 - 0.79 10.1 4.6 0.99 9.8 2.2 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger zf-H2C2_5 PF13909.1 KRH92351.1 - 8.6 6.8 18.3 4 7.8 0.4 3.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Integrase_Zn PF02022.14 KRH92352.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain TypeIII_RM_meth PF12564.3 KRH92352.1 - 0.1 12.6 1.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit rve PF00665.21 KRH92354.1 - 0.00072 19.6 0.0 0.00072 19.6 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.7 KRH92354.1 - 0.026 14.0 0.0 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 Putative peptidase (DUF1758) MOZ_SAS PF01853.13 KRH92355.1 - 9.2e-40 135.8 0.1 1.2e-35 122.4 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family Herpes_LMP1 PF05297.6 KRH92355.1 - 1.7 7.4 8.3 2.5 6.9 5.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ufd2P_core PF10408.4 KRH92357.1 - 3.2e-12 45.5 4.2 5e-12 44.8 2.9 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core Latarcin PF10279.4 KRH92357.1 - 0.0085 16.2 0.2 0.019 15.1 0.1 1.7 1 1 0 1 1 1 1 Latarcin precursor DUF1043 PF06295.7 KRH92357.1 - 0.036 13.7 0.1 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) rve PF00665.21 KRH92358.1 - 1.5e-18 67.0 0.0 2.1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH92358.1 - 0.0009 18.6 0.3 0.0034 16.7 0.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger gag_pre-integrs PF13976.1 KRH92358.1 - 0.001 18.6 1.0 0.0026 17.3 0.1 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain DDE_Tnp_IS240 PF13610.1 KRH92358.1 - 0.0013 18.6 0.3 0.0022 17.9 0.2 1.3 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KRH92358.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Na_H_Exchanger PF00999.16 KRH92359.1 - 8.1e-30 103.5 14.5 1.1e-29 103.1 10.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 KRH92359.1 - 0.048 12.9 2.9 0.12 11.6 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF21 rve PF00665.21 KRH92360.1 - 4.8e-24 84.7 0.1 6.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92360.1 - 0.00057 19.3 0.2 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Nuc_sug_transp PF04142.10 KRH92361.1 - 0.00098 18.2 13.1 0.086 11.9 0.3 2.4 1 1 1 2 2 2 2 Nucleotide-sugar transporter H_PPase PF03030.11 KRH92361.1 - 0.51 8.5 5.2 0.1 10.7 0.7 1.8 1 1 1 2 2 2 0 Inorganic H+ pyrophosphatase MerC PF03203.9 KRH92361.1 - 0.66 10.3 3.8 6.1 7.2 0.4 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein EamA PF00892.15 KRH92361.1 - 5.5 7.0 37.3 0.038 14.0 7.4 4.0 1 1 1 3 3 3 0 EamA-like transporter family DDE_Tnp_IS1595 PF12762.2 KRH92365.1 - 1.2e-22 80.3 0.2 1.7e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH92365.1 - 0.78 9.2 3.2 1.1 8.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Aa_trans PF01490.13 KRH92366.1 - 1.3e-25 89.7 50.2 1.7e-23 82.8 34.8 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_viral_C PF00336.13 KRH92368.1 - 0.16 11.2 0.5 0.19 10.9 0.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DDE_3 PF13358.1 KRH92369.1 - 1.1e-05 25.2 0.1 1.3e-05 24.9 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH92370.1 - 8e-12 45.0 0.4 8e-12 45.0 0.3 1.9 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.10 KRH92370.1 - 3e-05 23.7 0.5 0.0068 16.2 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 KRH92370.1 - 0.0026 17.2 0.2 0.008 15.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 KRH92370.1 - 0.009 16.7 0.0 0.035 14.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 KRH92370.1 - 0.0098 15.4 0.3 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 KRH92370.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_21 PF13276.1 KRH92370.1 - 0.017 15.0 1.1 0.021 14.8 0.2 1.6 2 0 0 2 2 2 0 HTH-like domain HTH_3 PF01381.17 KRH92370.1 - 0.087 12.6 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix Pkinase PF00069.20 KRH92372.1 - 5.2e-47 160.1 5.0 3.5e-45 154.1 3.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92372.1 - 2.8e-25 88.8 0.9 3.8e-24 85.1 0.6 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KRH92372.1 - 0.0082 15.2 0.1 0.0082 15.2 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KRH92372.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0102 PF02021.12 KRH92372.1 - 0.057 13.3 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 RWD PF05773.17 KRH92373.1 - 1.2e-05 25.1 1.0 0.0007 19.4 0.7 2.4 1 1 0 1 1 1 1 RWD domain zf-DHHC PF01529.15 KRH92374.1 - 3.5e-25 88.3 7.7 3.5e-25 88.3 5.3 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 KRH92374.1 - 0.054 13.6 1.7 0.054 13.6 1.2 1.9 2 0 0 2 2 2 0 Plexin repeat DUF2743 PF10899.3 KRH92374.1 - 3 7.1 5.1 1.4 8.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2743) rve PF00665.21 KRH92376.1 - 1.4e-20 73.6 0.0 2.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MGAT2 PF05060.9 KRH92376.1 - 0.00066 18.6 0.5 0.0012 17.8 0.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Flavi_NS1 PF00948.16 KRH92376.1 - 0.00093 17.7 2.4 0.0013 17.2 0.9 1.7 1 1 0 1 1 1 1 Flavivirus non-structural Protein NS1 rve_3 PF13683.1 KRH92376.1 - 0.00097 18.6 1.3 0.028 13.9 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92376.1 - 0.027 14.4 0.6 0.027 14.4 0.4 2.5 3 0 0 3 3 3 0 DDE domain gag_pre-integrs PF13976.1 KRH92376.1 - 0.052 13.1 0.3 0.16 11.6 0.2 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain RhoGAP PF00620.22 KRH92377.1 - 3.3e-18 65.7 2.7 5.3e-18 65.0 1.7 1.5 2 0 0 2 2 2 1 RhoGAP domain DUF1451 PF07295.6 KRH92377.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DHH PF01368.15 KRH92378.1 - 1.5e-07 31.1 0.5 1.1e-06 28.3 0.4 2.3 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 KRH92378.1 - 0.00053 20.1 0.4 0.0013 18.9 0.3 1.7 1 1 0 1 1 1 1 DHHA2 domain RVP_2 PF08284.6 KRH92379.1 - 7.8e-13 48.5 0.1 1.4e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92379.1 - 1.7e-08 34.8 0.1 3.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 KRH92379.1 - 0.0036 16.8 3.5 0.094 12.2 0.0 2.5 2 1 0 3 3 3 2 Putative peptidase (DUF1758) Peptidase_A2B PF12384.3 KRH92379.1 - 0.0046 16.3 1.5 0.0053 16.1 0.1 1.8 2 0 0 2 2 2 1 Ty3 transposon peptidase RVP PF00077.15 KRH92379.1 - 0.012 15.4 0.0 0.045 13.6 0.0 2.0 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 KRH92379.1 - 0.028 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag_pre-integrs PF13976.1 KRH92380.1 - 0.004 16.7 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-H2C2 PF09337.5 KRH92380.1 - 0.041 13.2 0.7 0.067 12.6 0.5 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Interfer-bind PF09294.5 KRH92381.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III NAD_binding_1 PF00175.16 KRH92382.1 - 4e-05 24.1 0.4 0.037 14.5 0.0 2.5 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain Prenyltransf PF01255.14 KRH92384.1 - 7e-26 90.7 7.3 1.8e-12 46.8 0.5 3.3 2 1 1 3 3 3 3 Putative undecaprenyl diphosphate synthase Med12-LCEWAV PF12145.3 KRH92384.1 - 0.0083 14.6 0.4 0.012 14.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain rve PF00665.21 KRH92385.1 - 2.7e-19 69.4 0.0 7.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92385.1 - 0.0057 16.1 0.0 0.02 14.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_Zn PF02022.14 KRH92385.1 - 0.014 14.8 1.5 0.04 13.3 1.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain Inhibitor_G39P PF11417.3 KRH92385.1 - 0.016 15.1 1.9 0.43 10.6 0.0 2.7 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P gag_pre-integrs PF13976.1 KRH92385.1 - 0.03 13.9 1.8 0.032 13.8 0.2 1.9 2 0 0 2 2 2 0 GAG-pre-integrase domain Radical_SAM PF04055.16 KRH92385.1 - 0.047 13.8 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily DEAD PF00270.24 KRH92386.1 - 4e-25 88.2 0.1 5.5e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KRH92386.1 - 7.3e-06 25.9 5.8 1.2e-05 25.2 0.3 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KRH92386.1 - 0.00019 20.8 0.0 0.00045 19.6 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SE PF00437.15 KRH92386.1 - 0.0011 17.9 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KRH92386.1 - 0.0034 16.6 0.5 0.0064 15.7 0.3 1.5 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 KRH92386.1 - 0.0043 17.2 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KRH92386.1 - 0.032 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KRH92386.1 - 0.043 13.7 4.8 0.27 11.1 1.5 2.7 1 1 1 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 KRH92386.1 - 0.067 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain Dynamin_N PF00350.18 KRH92387.1 - 1.3e-29 103.1 2.1 1e-28 100.2 1.5 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KRH92387.1 - 1.3e-07 31.6 0.5 0.014 15.3 0.0 2.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KRH92387.1 - 0.0025 18.6 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KRH92387.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KRH92387.1 - 0.042 14.0 1.2 0.18 11.9 0.1 2.2 1 1 1 2 2 2 0 RNA helicase Miro PF08477.8 KRH92387.1 - 0.043 14.3 0.1 0.11 13.0 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 KRH92387.1 - 0.056 12.8 0.2 1.2 8.5 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KRH92387.1 - 0.068 13.0 0.1 0.18 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KRH92387.1 - 0.096 12.9 2.4 0.25 11.6 1.5 2.0 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KRH92387.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain TFIID-31kDa PF02291.10 KRH92388.1 - 4.1e-20 71.8 0.1 4.4e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 KRH92388.1 - 1.7e-06 28.0 0.2 2.7e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KRH92388.1 - 8.2e-06 25.4 0.1 1.6e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 KRH92388.1 - 2.8e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KRH92388.1 - 0.00023 21.0 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KRH92388.1 - 0.0015 18.4 0.2 0.0027 17.7 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 KRH92388.1 - 0.02 14.7 0.1 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1931 PF09123.6 KRH92388.1 - 0.028 14.3 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) AAA_32 PF13654.1 KRH92388.1 - 0.081 11.5 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain RTP PF02334.11 KRH92389.1 - 0.11 12.5 3.0 0.18 11.7 1.9 1.4 1 1 0 1 1 1 0 Replication terminator protein TFIIE_alpha PF02002.12 KRH92390.1 - 7.4e-12 44.7 1.5 7.4e-12 44.7 1.0 2.2 3 0 0 3 3 3 1 TFIIE alpha subunit HypA PF01155.14 KRH92390.1 - 0.043 13.4 0.2 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KRH92390.1 - 0.088 12.7 1.3 0.22 11.4 0.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Glyco_hydro_100 PF12899.2 KRH92390.1 - 0.13 10.6 0.8 0.23 9.8 0.1 1.8 2 0 0 2 2 2 0 Alkaline and neutral invertase C1_4 PF07975.7 KRH92390.1 - 1.9 8.5 5.2 14 5.7 0.2 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain rve PF00665.21 KRH92392.1 - 4e-24 85.0 0.1 1.5e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 KRH92392.1 - 1.4e-06 27.5 0.0 3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 KRH92392.1 - 0.0015 17.9 0.0 0.0048 16.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 KRH92392.1 - 0.0039 16.9 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_3 PF13456.1 KRH92392.1 - 0.0069 16.1 0.6 0.021 14.6 0.1 2.1 2 1 0 2 2 2 1 Reverse transcriptase-like gag_pre-integrs PF13976.1 KRH92392.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain tRNA-synt_2 PF00152.15 KRH92393.1 - 2.6e-17 62.6 0.0 2.7e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KRH92393.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) FERM_C PF09380.5 KRH92394.1 - 0.084 13.0 0.9 0.092 12.9 0.7 1.1 1 0 0 1 1 1 0 FERM C-terminal PH-like domain rve PF00665.21 KRH92395.1 - 1.5e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SHMT PF00464.14 KRH92395.1 - 0.073 11.4 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase rve PF00665.21 KRH92396.1 - 6.4e-17 61.7 0.2 7.6e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain ADH_N PF08240.7 KRH92396.1 - 0.031 14.0 0.6 0.042 13.6 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DDE_Tnp_IS240 PF13610.1 KRH92396.1 - 0.053 13.4 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 DDE domain DDE_Tnp_ISL3 PF01610.12 KRH92396.1 - 0.064 12.8 0.5 0.088 12.3 0.3 1.3 1 0 0 1 1 1 0 Transposase rve PF00665.21 KRH92397.1 - 2.8e-06 27.4 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92397.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH92398.1 - 7.4e-05 22.0 3.2 0.00013 21.2 2.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Herpes_BLRF2 PF05812.7 KRH92398.1 - 0.019 14.7 0.2 0.03 14.1 0.2 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein HSP70 PF00012.15 KRH92400.1 - 1.6e-07 29.6 0.9 3e-07 28.7 0.3 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KRH92400.1 - 1.4e-05 23.8 0.0 2.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 KRH92400.1 - 0.017 13.5 0.0 0.026 12.9 0.0 1.3 1 0 0 1 1 1 0 Actin ATP-synt_S1 PF05827.7 KRH92400.1 - 0.055 12.7 0.1 0.098 11.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) RNase_T PF00929.19 KRH92401.1 - 2.4e-20 73.4 1.2 3e-20 73.1 0.1 1.7 2 0 0 2 2 2 1 Exonuclease zf-RING_2 PF13639.1 KRH92402.1 - 5.2e-06 26.1 2.5 5.2e-06 26.1 1.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KRH92402.1 - 0.00018 21.1 4.9 0.00033 20.3 1.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KRH92402.1 - 0.00051 20.0 4.7 0.002 18.1 3.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KRH92402.1 - 0.0013 18.2 5.0 0.0013 18.2 3.5 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH92402.1 - 0.0019 18.1 4.9 0.0019 18.1 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KRH92402.1 - 0.033 14.0 1.4 0.068 13.0 0.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KRH92402.1 - 0.041 13.5 4.6 0.055 13.1 1.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KRH92402.1 - 0.11 12.4 4.0 0.28 11.1 2.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING rve PF00665.21 KRH92404.1 - 2.8e-27 95.2 0.0 6.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92404.1 - 5.5e-05 22.5 0.1 0.00013 21.3 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain SWIB PF02201.13 KRH92405.1 - 6.5e-11 41.7 1.3 6.5e-11 41.7 0.9 2.5 4 0 0 4 4 4 1 SWIB/MDM2 domain SKIP_SNW PF02731.10 KRH92405.1 - 0.022 14.2 0.9 0.048 13.1 0.7 1.6 1 0 0 1 1 1 0 SKIP/SNW domain EB1 PF03271.12 KRH92406.1 - 3.6e-05 23.7 6.7 3.6e-05 23.7 4.7 2.9 4 1 0 4 4 4 1 EB1-like C-terminal motif rve PF00665.21 KRH92408.1 - 1.3e-08 34.9 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SHMT PF00464.14 KRH92408.1 - 0.12 10.6 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Corona_nucleoca PF00937.13 KRH92409.1 - 0.08 11.8 0.6 0.12 11.3 0.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NOT2_3_5 PF04153.13 KRH92410.1 - 1.9e-30 105.4 12.3 1.9e-30 105.4 8.6 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family rRNA_processing PF08524.6 KRH92411.1 - 0.23 11.2 8.8 0.3 10.8 6.1 1.2 1 0 0 1 1 1 0 rRNA processing Ribosomal_L18_c PF14204.1 KRH92411.1 - 0.58 10.7 7.5 0.14 12.7 2.8 1.6 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Kri1 PF05178.7 KRH92411.1 - 1.4 9.2 5.9 5.4 7.3 2.3 2.1 1 1 1 2 2 2 0 KRI1-like family Erv26 PF04148.8 KRH92413.1 - 4.1e-19 68.8 17.8 2.6e-17 62.9 12.4 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Bac_export_3 PF01313.14 KRH92413.1 - 3.5 7.3 11.5 0.065 12.9 2.7 2.1 2 1 0 2 2 2 0 Bacterial export proteins, family 3 DnaB PF00772.16 KRH92415.1 - 0.041 13.7 2.0 3.3 7.6 0.1 3.5 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain Fe-ADH_2 PF13685.1 KRH92415.1 - 0.11 11.7 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Histone PF00125.19 KRH92416.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KRH92416.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Apo-CII PF05355.6 KRH92416.1 - 0.0066 16.2 0.2 0.0086 15.9 0.1 1.3 1 0 0 1 1 1 1 Apolipoprotein C-II Spore_III_AF PF09581.5 KRH92416.1 - 0.027 14.3 0.5 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RVT_3 PF13456.1 KRH92418.1 - 0.0072 16.0 0.0 0.045 13.5 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 KRH92419.1 - 7.7e-17 61.3 0.8 1.1e-16 60.9 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4367 PF14285.1 KRH92419.1 - 0.013 14.8 0.1 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) RVT_1 PF00078.22 KRH92420.1 - 2.9e-17 62.7 0.4 6.1e-17 61.6 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH92421.1 - 1.1e-19 70.6 0.0 2.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_II PF05188.12 KRH92421.1 - 0.011 15.7 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 MutS domain II Ferritin PF00210.19 KRH92421.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain PCI PF01399.22 KRH92423.1 - 2.5e-07 30.9 2.8 3.5e-07 30.4 0.5 2.3 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KRH92423.1 - 0.0061 16.3 0.2 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Zip PF02535.17 KRH92424.1 - 3.5e-27 95.2 14.5 4.5e-27 94.8 10.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AKAP7_RIRII_bdg PF10470.4 KRH92426.1 - 0.0051 16.6 0.1 0.0081 15.9 0.1 1.4 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein WAC_Acf1_DNA_bd PF10537.4 KRH92426.1 - 0.068 13.3 1.1 0.34 11.0 0.7 2.1 1 1 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Hemocyanin_N PF03722.9 KRH92426.1 - 0.073 13.2 2.5 0.16 12.1 0.8 1.9 1 1 1 2 2 2 0 Hemocyanin, all-alpha domain Ribosomal_L24e PF01246.15 KRH92428.1 - 1.1e-10 41.1 0.5 2.3e-10 40.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e TraI_2 PF07514.6 KRH92428.1 - 0.048 12.4 0.1 0.059 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative helicase Ribosomal_L29 PF00831.18 KRH92430.1 - 5e-08 32.5 5.8 2e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Phage_Nu1 PF07471.7 KRH92430.1 - 0.0034 16.8 0.3 0.0042 16.5 0.2 1.1 1 0 0 1 1 1 1 Phage DNA packaging protein Nu1 VP40 PF07447.7 KRH92430.1 - 0.038 13.0 0.8 0.047 12.7 0.5 1.1 1 0 0 1 1 1 0 Matrix protein VP40 PLC-beta_C PF08703.5 KRH92430.1 - 0.15 11.7 8.3 0.19 11.4 5.8 1.1 1 0 0 1 1 1 0 PLC-beta C terminal DUF3552 PF12072.3 KRH92431.1 - 0.29 10.3 3.0 0.28 10.3 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Myc-LZ PF02344.10 KRH92431.1 - 1.8 8.2 4.6 9.2 5.9 0.1 2.8 3 0 0 3 3 3 0 Myc leucine zipper domain SAC3_GANP PF03399.11 KRH92432.1 - 0.02 14.4 2.5 0.029 13.9 1.7 1.3 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Ribosomal_L17 PF01196.14 KRH92432.1 - 0.1 13.1 4.5 1.9 9.0 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L17 PPV_E2_C PF00511.12 KRH92432.1 - 0.24 11.3 1.4 0.4 10.6 0.4 1.7 2 0 0 2 2 2 0 E2 (early) protein, C terminal TEX12 PF15219.1 KRH92433.1 - 0.15 12.0 0.5 0.15 12.0 0.4 1.1 1 0 0 1 1 1 0 Testis-expressed 12 PAH PF02671.16 KRH92434.1 - 0.0019 17.7 6.0 0.0038 16.8 0.2 2.9 2 1 0 2 2 2 1 Paired amphipathic helix repeat DUF869 PF05911.6 KRH92434.1 - 0.0065 14.7 2.7 0.0069 14.6 1.9 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF1978 PF09321.5 KRH92434.1 - 0.037 13.4 7.4 0.074 12.4 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) RPOL_N PF14700.1 KRH92434.1 - 0.14 11.3 1.5 0.19 10.9 0.4 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Rsd_AlgQ PF04353.8 KRH92434.1 - 0.66 9.6 6.5 1 9.0 4.5 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2203 PF09969.4 KRH92434.1 - 0.76 10.0 4.4 4.5 7.5 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cauli_AT PF03233.8 KRH92434.1 - 4.3 7.0 16.4 32 4.1 11.4 2.0 1 1 0 1 1 1 0 Aphid transmission protein FadA PF09403.5 KRH92434.1 - 9.1 6.3 9.4 1 9.3 0.8 2.2 1 1 0 2 2 2 0 Adhesion protein FadA CPSase_L_D2 PF02786.12 KRH92435.1 - 3.9e-23 81.8 0.1 6.6e-20 71.2 0.0 3.0 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KRH92435.1 - 0.0071 15.1 0.2 0.021 13.6 0.0 1.8 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon E2_bind PF08825.5 KRH92435.1 - 0.035 13.8 0.3 0.39 10.4 0.0 2.8 3 0 0 3 3 3 0 E2 binding domain TFIIA PF03153.8 KRH92436.1 - 0.0095 15.8 21.1 0.014 15.3 14.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDE_Tnp_IS1595 PF12762.2 KRH92438.1 - 2.4e-10 40.4 0.0 2.6e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain Fim-adh_lectin PF09222.5 KRH92438.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Peptidase_M24 PF00557.19 KRH92439.1 - 1.5e-21 76.9 0.0 2.7e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Metallopeptidase family M24 Glyco_transf_20 PF00982.16 KRH92440.1 - 8.3e-13 47.6 0.0 9.8e-13 47.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Sec3_C_2 PF15278.1 KRH92442.1 - 0.031 14.4 0.3 0.078 13.1 0.2 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Claudin_2 PF13903.1 KRH92442.1 - 4.8 6.8 7.6 1.6 8.3 0.2 2.9 2 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction NanE PF04131.9 KRH92444.1 - 0.0044 15.9 0.2 0.0049 15.8 0.2 1.0 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF1512 PF07431.7 KRH92444.1 - 0.03 13.0 1.1 0.031 13.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Alpha-2-MRAP_C PF06401.6 KRH92444.1 - 0.033 14.0 2.9 0.044 13.6 2.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain tRNA-Thr_ED PF08915.6 KRH92444.1 - 0.096 12.6 0.5 0.12 12.3 0.4 1.3 1 1 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase AAA_11 PF13086.1 KRH92444.1 - 0.11 11.9 0.7 0.13 11.7 0.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3080 PF11279.3 KRH92444.1 - 0.13 11.3 2.5 0.16 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Vpu PF00558.14 KRH92444.1 - 2.9 7.5 5.8 1.8 8.1 0.3 2.5 2 1 1 3 3 3 0 Vpu protein CARDB PF07705.6 KRH92445.1 - 0.014 15.4 0.3 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 CARDB RVT_1 PF00078.22 KRH92446.1 - 3e-21 75.7 0.2 4.2e-21 75.2 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAP2 PF01569.16 KRH92449.1 - 4.2e-07 29.6 2.9 4.2e-07 29.6 2.0 2.2 2 1 0 2 2 2 1 PAP2 superfamily SPC25 PF06703.6 KRH92449.1 - 0.036 13.6 1.6 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sigma54_activ_2 PF14532.1 KRH92450.1 - 0.00065 19.7 0.0 5.2 7.1 0.0 4.0 2 1 3 5 5 5 2 Sigma-54 interaction domain NOGCT PF08155.6 KRH92450.1 - 0.053 13.2 1.2 15 5.4 0.0 4.5 4 0 0 4 4 4 0 NOGCT (NUC087) domain Bile_Hydr_Trans PF04775.9 KRH92450.1 - 0.17 11.6 1.3 48 3.6 0.0 3.8 4 0 0 4 4 4 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region UPAR_LY6 PF00021.16 KRH92450.1 - 3.6 8.0 12.3 4.4 7.8 1.9 3.3 1 1 2 3 3 3 0 u-PAR/Ly-6 domain GAGA_bind PF06217.7 KRH92450.1 - 3.8 7.3 19.8 6.3 6.6 3.1 4.1 1 1 3 4 4 4 0 GAGA binding protein-like family Aa_trans PF01490.13 KRH92451.1 - 2.7e-22 78.8 46.4 3.6e-22 78.4 18.8 2.8 2 2 0 2 2 2 2 Transmembrane amino acid transporter protein Gp_dh_C PF02800.15 KRH92453.1 - 3.5e-57 192.2 0.5 4.8e-57 191.8 0.3 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KRH92453.1 - 9.6e-41 139.2 0.9 1.4e-40 138.7 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KRH92453.1 - 0.0093 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MoaF PF10703.4 KRH92453.1 - 0.044 12.8 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F ELFV_dehydrog PF00208.16 KRH92453.1 - 0.11 12.0 0.4 0.21 11.1 0.0 1.7 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Yip1 PF04893.12 KRH92455.1 - 0.059 12.8 16.2 0.24 10.8 7.7 2.7 2 1 0 2 2 2 0 Yip1 domain Actin PF00022.14 KRH92456.1 - 2e-05 23.2 0.1 5.3e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Actin DDE_3 PF13358.1 KRH92459.1 - 1.4e-19 70.2 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH92459.1 - 9.1e-10 38.4 8.9 4.9e-09 36.1 2.2 3.1 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 KRH92459.1 - 2e-08 34.3 0.5 3.4e-08 33.6 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KRH92459.1 - 2.2e-06 28.3 1.2 9.9e-06 26.2 0.6 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.7 KRH92459.1 - 1.1e-05 25.0 0.5 0.0032 17.0 0.0 2.6 2 0 0 2 2 2 1 HTH domain HTH_7 PF02796.10 KRH92459.1 - 0.0002 21.1 1.0 0.0082 15.9 0.0 3.2 3 1 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_ECF PF07638.6 KRH92459.1 - 0.006 16.2 0.2 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.1 KRH92459.1 - 0.0062 16.5 2.7 0.041 13.8 0.5 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 KRH92459.1 - 0.0065 16.0 3.3 0.026 14.1 0.4 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 KRH92459.1 - 0.0093 15.9 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain HTH_6 PF01418.12 KRH92459.1 - 0.024 14.3 0.1 0.056 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_22 PF13309.1 KRH92459.1 - 0.039 13.6 1.5 0.43 10.3 0.1 2.9 2 1 0 2 2 2 0 HTH domain HTH_12 PF08461.5 KRH92459.1 - 0.066 12.9 1.8 7.5 6.3 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_36 PF13730.1 KRH92459.1 - 0.067 13.3 0.4 0.98 9.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.13 KRH92459.1 - 0.1 12.3 0.7 0.19 11.4 0.5 1.5 1 0 0 1 1 1 0 'Paired box' domain Put_DNA-bind_N PF06971.8 KRH92459.1 - 0.11 12.3 1.7 0.3 10.8 0.3 2.4 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus HTH_26 PF13443.1 KRH92459.1 - 0.14 12.4 3.3 0.84 9.8 0.1 3.2 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_17 PF12728.2 KRH92459.1 - 0.93 9.7 4.9 8 6.8 0.0 3.2 3 1 0 3 3 3 0 Helix-turn-helix domain Hist_deacetyl PF00850.14 KRH92460.1 - 3.8e-37 128.2 1.1 2.4e-36 125.6 0.8 1.8 1 1 0 1 1 1 1 Histone deacetylase domain AAA PF00004.24 KRH92461.1 - 1.3e-45 154.8 0.1 3.5e-45 153.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH92461.1 - 6.2e-09 35.6 0.4 3.7e-08 33.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KRH92461.1 - 1.6e-08 34.6 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KRH92461.1 - 1.5e-06 28.3 0.1 8.6e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KRH92461.1 - 5.8e-06 26.4 0.5 0.00028 21.0 0.3 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KRH92461.1 - 8.6e-06 24.8 0.0 1.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 KRH92461.1 - 8.7e-06 25.4 1.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KRH92461.1 - 2.1e-05 24.2 0.1 0.0013 18.4 0.0 2.8 3 0 0 3 3 2 1 NTPase AAA_14 PF13173.1 KRH92461.1 - 0.00018 21.4 0.0 0.00047 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KRH92461.1 - 0.00041 19.4 0.0 0.0012 17.8 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KRH92461.1 - 0.00047 19.8 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KRH92461.1 - 0.00087 18.1 0.0 0.002 16.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_30 PF13604.1 KRH92461.1 - 0.00093 18.8 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KRH92461.1 - 0.0011 18.0 0.2 0.0024 16.9 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin UPF0079 PF02367.12 KRH92461.1 - 0.0013 18.3 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KRH92461.1 - 0.0015 18.2 0.2 0.022 14.4 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 KRH92461.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH92461.1 - 0.0019 19.0 0.0 0.0052 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KRH92461.1 - 0.0019 17.8 0.0 0.0037 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KRH92461.1 - 0.002 18.2 0.0 0.0064 16.6 0.0 2.0 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 KRH92461.1 - 0.0022 17.5 0.3 0.072 12.5 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 KRH92461.1 - 0.0032 16.8 1.1 0.064 12.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KRH92461.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KRH92461.1 - 0.0043 16.2 0.1 0.012 14.7 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KRH92461.1 - 0.0053 16.4 2.3 0.033 13.8 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase AAA_3 PF07726.6 KRH92461.1 - 0.012 15.2 0.1 0.044 13.3 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KRH92461.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Bac_DnaA PF00308.13 KRH92461.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 KRH92461.1 - 0.036 12.9 0.3 0.082 11.7 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ADIP PF11559.3 KRH92461.1 - 0.051 13.4 1.3 0.11 12.3 0.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AAA_18 PF13238.1 KRH92461.1 - 0.053 13.8 0.0 0.2 11.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KRH92461.1 - 0.098 12.9 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 KRH92461.1 - 0.13 12.5 3.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KRH92461.1 - 0.31 10.1 3.0 0.93 8.5 0.0 2.6 2 1 0 3 3 3 0 KaiC GRIN_C PF15235.1 KRH92462.1 - 0.09 12.8 0.3 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus DUF2393 PF09624.5 KRH92462.1 - 0.97 8.9 6.0 0.13 11.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) rve PF00665.21 KRH92463.1 - 1.9e-19 69.9 0.0 3.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KRH92463.1 - 0.00046 19.7 0.7 0.0012 18.4 0.5 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 KRH92463.1 - 0.0062 16.0 0.1 0.025 14.0 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain FACT-Spt16_Nlob PF14826.1 KRH92464.1 - 1.1e-14 54.2 2.1 1.5e-14 53.8 0.6 1.8 2 1 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Collagen PF01391.13 KRH92464.1 - 0.23 11.0 13.0 0.37 10.3 9.0 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) rve PF00665.21 KRH92466.1 - 4.5e-09 36.4 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92466.1 - 0.003 17.0 0.1 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 KRH92468.1 - 4.2e-06 26.2 0.0 5.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 KRH92468.1 - 0.00031 20.1 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 KRH92468.1 - 0.0006 19.1 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 KRH92468.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 KRH92468.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Terminase_5 PF06056.7 KRH92468.1 - 0.0052 16.3 0.0 0.0098 15.4 0.0 1.5 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.1 KRH92468.1 - 0.0079 16.3 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.11 KRH92468.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 PAX PF00292.13 KRH92468.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain DUF722 PF05263.6 KRH92468.1 - 0.096 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF722) PCI PF01399.22 KRH92468.1 - 0.12 12.6 0.1 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 PCI domain HTH_38 PF13936.1 KRH92468.1 - 0.14 11.7 0.1 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain AAA PF00004.24 KRH92469.1 - 2.8e-41 140.7 0.0 6.1e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH92469.1 - 2.9e-05 23.8 0.3 0.00022 20.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KRH92469.1 - 3.3e-05 23.8 0.1 0.0002 21.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KRH92469.1 - 5e-05 22.4 0.1 0.00011 21.2 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KRH92469.1 - 0.00043 20.3 0.1 0.051 13.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KRH92469.1 - 0.00074 19.6 1.0 0.11 12.6 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KRH92469.1 - 0.001 18.9 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KRH92469.1 - 0.0011 18.5 0.6 0.2 11.1 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 KRH92469.1 - 0.0015 18.4 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH92469.1 - 0.0043 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 KRH92469.1 - 0.0046 16.2 0.1 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KRH92469.1 - 0.019 14.1 0.4 0.069 12.3 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KRH92469.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KRH92469.1 - 0.043 12.8 0.6 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 KRH92469.1 - 0.077 13.8 0.1 0.28 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KRH92469.1 - 0.11 12.7 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase RVP PF00077.15 KRH92470.1 - 6e-09 35.7 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92470.1 - 6e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92470.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KRH92470.1 - 0.05 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease s48_45 PF07422.8 KRH92470.1 - 2.6 8.1 8.3 0.093 12.8 0.5 2.2 2 1 0 2 2 2 0 Sexual stage antigen s48/45 domain Helicase_C PF00271.26 KRH92471.1 - 6.1e-15 54.8 0.3 1.3e-14 53.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 KRH92471.1 - 0.0097 15.6 1.3 0.034 13.8 0.4 2.2 2 0 0 2 2 2 1 RQC domain Ran_BP1 PF00638.13 KRH92472.1 - 3e-05 24.0 1.7 0.0062 16.5 0.3 2.8 2 0 0 2 2 2 2 RanBP1 domain FbpA PF05833.6 KRH92473.1 - 0.00013 20.6 26.5 0.00013 20.6 18.4 3.2 1 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1625 PF07787.7 KRH92474.1 - 0.0067 15.7 0.0 0.0067 15.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1625) ATP-synt_E PF05680.7 KRH92474.1 - 0.33 10.9 5.2 0.33 10.9 2.6 1.8 1 1 0 1 1 1 0 ATP synthase E chain Aa_trans PF01490.13 KRH92475.1 - 1.1e-21 76.8 8.8 1.4e-21 76.4 6.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KRH92475.1 - 3.4e-08 32.7 11.8 4.9e-08 32.2 8.0 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4131 PF13567.1 KRH92475.1 - 0.069 12.5 0.2 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AOX PF01786.12 KRH92476.1 - 2.1e-70 236.3 0.2 2.7e-70 235.9 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.8 KRH92476.1 - 0.064 12.7 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 ERO1 PF04137.10 KRH92477.1 - 3.4e-19 69.0 14.9 6.7e-11 41.7 1.6 3.1 1 1 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RVT_1 PF00078.22 KRH92478.1 - 4.3e-27 94.8 0.3 6.7e-27 94.2 0.2 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH92478.1 - 0.022 13.7 0.3 0.03 13.2 0.2 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UBA_e1_C PF09358.5 KRH92478.1 - 0.091 12.9 0.6 0.14 12.3 0.4 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain ydhR PF08803.6 KRH92479.1 - 0.12 12.4 0.3 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR TRCF PF03461.10 KRH92482.1 - 0.073 13.0 3.6 0.15 12.0 2.5 1.6 1 0 0 1 1 1 0 TRCF domain DDE_Tnp_ISAZ013 PF07592.6 KRH92482.1 - 0.2 10.3 5.2 0.3 9.7 3.6 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Trypan_glycop PF00913.14 KRH92482.1 - 1.6 7.5 7.8 2.9 6.6 5.4 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Ras PF00071.17 KRH92483.1 - 4.1e-46 156.3 0.0 5.9e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH92483.1 - 2.2e-14 53.9 0.0 8.2e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KRH92483.1 - 2.3e-08 33.4 0.0 3.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KRH92483.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 KRH92483.1 - 0.14 11.6 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AhpC-TSA PF00578.16 KRH92485.1 - 1.7e-18 66.4 0.2 3.3e-18 65.5 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KRH92485.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Redoxin DUF3548 PF12068.3 KRH92485.1 - 0.084 12.1 0.1 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Furin-like PF00757.15 KRH92486.1 - 0.03 13.9 8.0 0.036 13.7 5.5 1.3 1 0 0 1 1 1 0 Furin-like cysteine rich region zf-CCCH_2 PF14608.1 KRH92486.1 - 0.061 13.3 2.6 0.061 13.3 1.8 3.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type CDV3 PF15359.1 KRH92486.1 - 0.11 12.6 3.9 0.16 12.0 2.7 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Latarcin PF10279.4 KRH92491.1 - 0.2 11.8 2.8 0.23 11.6 2.0 1.1 1 0 0 1 1 1 0 Latarcin precursor Lin-8 PF03353.10 KRH92491.1 - 5.5 6.1 11.2 6.4 5.9 7.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Asp_protease_2 PF13650.1 KRH92492.1 - 2.5e-05 24.7 0.0 3.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92492.1 - 0.0049 16.6 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 KRH92492.1 - 0.031 13.5 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Herpes_UL25 PF01499.11 KRH92493.1 - 0.013 13.8 0.3 0.017 13.4 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Spp-24 PF07448.6 KRH92493.1 - 0.015 15.2 0.2 0.027 14.4 0.2 1.5 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) SPOUT_MTase PF02590.12 KRH92493.1 - 0.17 11.6 2.0 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase UQ_con PF00179.21 KRH92494.1 - 3.2e-47 159.4 0.0 3.7e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KRH92494.1 - 1.5e-05 24.7 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KRH92494.1 - 0.0015 18.4 1.9 0.0023 17.8 1.2 1.5 1 1 0 1 1 1 1 RWD domain rve PF00665.21 KRH92495.1 - 3e-06 27.3 0.1 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92495.1 - 0.0014 18.0 0.1 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 KRH92496.1 - 7.4e-05 22.0 3.2 0.00013 21.2 2.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Herpes_BLRF2 PF05812.7 KRH92496.1 - 0.019 14.7 0.2 0.03 14.1 0.2 1.4 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein UCH PF00443.24 KRH92500.1 - 1.8e-07 30.5 8.4 3.4e-06 26.3 1.0 2.3 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH92500.1 - 2.3e-05 24.0 0.4 2.3e-05 24.0 0.3 2.0 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF751 PF05421.6 KRH92500.1 - 0.077 13.2 1.6 0.13 12.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF751) Pox_D5 PF03288.11 KRH92501.1 - 2 8.7 11.0 14 6.0 4.2 3.6 2 1 0 2 2 2 0 Poxvirus D5 protein-like HTH_29 PF13551.1 KRH92502.1 - 7.2e-05 22.9 0.0 8.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 KRH92502.1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KRH92502.1 - 0.00071 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KRH92502.1 - 0.0016 19.2 0.0 0.0026 18.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.13 KRH92502.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain Sigma70_r4_2 PF08281.7 KRH92502.1 - 0.026 13.9 0.0 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 Phage_pRha PF09669.5 KRH92502.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) DDE_3 PF13358.1 KRH92503.1 - 2.3e-28 98.8 0.0 2.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-6 PF01912.13 KRH92504.1 - 8.1e-69 230.7 1.9 9.6e-69 230.4 1.3 1.1 1 0 0 1 1 1 1 eIF-6 family RVT_1 PF00078.22 KRH92505.1 - 1.1e-12 47.8 0.1 1.9e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 KRH92506.1 - 2.8e-12 46.0 2.0 8.6e-06 25.4 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Sof1 PF04158.9 KRH92506.1 - 6.4e-09 35.7 8.3 1.8e-08 34.3 5.7 1.8 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KRH92506.1 - 0.0059 16.3 0.1 0.34 10.6 0.0 2.8 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 KRH92507.1 - 1.7e-06 27.6 0.7 0.0022 17.8 0.2 3.5 4 1 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L7Ae PF01248.21 KRH92508.1 - 3.7e-19 68.0 0.9 8.2e-19 66.9 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DDE_Tnp_ISL3 PF01610.12 KRH92508.1 - 0.059 12.9 0.7 0.089 12.3 0.5 1.3 1 0 0 1 1 1 0 Transposase OmdA PF13376.1 KRH92508.1 - 0.3 10.7 2.4 0.4 10.3 0.2 2.2 2 1 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Mg_trans_NIPA PF05653.9 KRH92509.1 - 5.7e-29 101.0 23.8 3.7e-20 72.0 4.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Nodulin_late PF07127.6 KRH92509.1 - 0.047 13.8 1.0 0.047 13.8 0.7 5.3 4 1 1 5 5 5 0 Late nodulin protein DUF2052 PF09747.4 KRH92511.1 - 0.026 14.4 2.1 0.036 13.9 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.8 KRH92511.1 - 0.17 11.3 3.4 0.21 11.0 2.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 KRH92511.1 - 0.28 10.9 4.9 0.39 10.4 3.4 1.3 1 0 0 1 1 1 0 DDHD domain Nexin_C PF08628.7 KRH92511.1 - 0.29 11.2 4.0 0.64 10.1 2.8 1.7 1 1 0 1 1 1 0 Sorting nexin C terminal Sof1 PF04158.9 KRH92511.1 - 1.1 9.3 8.6 2.4 8.2 5.6 1.9 1 1 1 2 2 2 0 Sof1-like domain Na_trans_assoc PF06512.8 KRH92511.1 - 1.1 9.1 10.6 0.6 10.0 4.9 1.7 1 1 1 2 2 2 0 Sodium ion transport-associated Histone PF00125.19 KRH92512.1 - 3.5e-05 23.8 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KRH92512.1 - 0.0036 17.3 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone rve PF00665.21 KRH92513.1 - 4e-18 65.6 0.0 7.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92513.1 - 0.006 16.0 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH92513.1 - 0.011 15.1 0.0 0.033 13.5 0.0 1.9 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger rve PF00665.21 KRH92514.1 - 7.9e-16 58.2 0.0 1.5e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92514.1 - 0.0019 17.7 0.1 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chs3p PF12271.3 KRH92516.1 - 3.3e-07 29.5 30.8 1.7e-06 27.2 21.3 2.2 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Cyclin_N PF00134.18 KRH92517.1 - 1.2e-20 73.3 2.5 1.5e-20 73.0 0.3 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain TrmB PF01978.14 KRH92518.1 - 0.027 14.1 0.4 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2629 PF10945.3 KRH92518.1 - 0.14 11.5 0.0 23 4.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) D5_N PF08706.6 KRH92518.1 - 0.17 11.9 4.4 0.15 12.1 1.6 2.0 2 1 0 2 2 2 0 D5 N terminal like mRNA_triPase PF02940.10 KRH92519.1 - 6.8e-28 97.8 4.7 2.4e-26 92.8 3.2 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain DUF1053 PF06327.9 KRH92519.1 - 0.071 13.4 1.3 1.7 9.0 0.0 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) SHS2_Rpb7-N PF03876.12 KRH92520.1 - 0.00014 21.9 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 KRH92520.1 - 0.00016 21.8 2.7 0.0045 17.1 0.3 2.5 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 DUF663 PF04950.7 KRH92522.1 - 2.3e-08 33.3 15.8 2.4e-07 30.0 10.8 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF663) PRP1_N PF06424.7 KRH92522.1 - 1.3 9.3 16.3 1.3 9.3 0.8 2.5 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Pkinase PF00069.20 KRH92523.1 - 6.5e-69 231.9 0.0 7.7e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92523.1 - 3.6e-39 134.3 0.0 6.6e-39 133.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH92523.1 - 0.00024 20.1 0.0 0.00041 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KRH92523.1 - 0.0023 17.6 0.0 0.0065 16.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KRH92523.1 - 0.021 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flo11 PF10182.4 KRH92523.1 - 0.075 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Flo11 domain TBP PF00352.16 KRH92525.1 - 1.9e-69 229.0 1.4 9.4e-36 121.0 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KRH92525.1 - 0.00013 21.9 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) rve PF00665.21 KRH92526.1 - 7.9e-10 38.8 0.0 1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS1595 PF12762.2 KRH92526.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain MULE PF10551.4 KRH92526.1 - 0.045 13.9 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain Glyco_hydro_71 PF03659.9 KRH92526.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 DDE_Tnp_IS240 PF13610.1 KRH92526.1 - 0.12 12.3 0.1 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 DDE domain XisI PF08869.6 KRH92526.1 - 0.2 11.7 1.4 1.2 9.3 0.1 2.0 1 1 1 2 2 2 0 XisI protein Dus PF01207.12 KRH92527.1 - 3.5e-42 144.3 0.0 4.4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Gas_vesicle_C PF01304.12 KRH92527.1 - 0.054 13.1 2.3 2.5 7.8 0.0 3.5 3 1 1 4 4 4 0 Gas vesicles protein GVPc repeated domain DUF1720 PF08226.6 KRH92527.1 - 0.077 13.0 2.0 1.8 8.7 1.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) DUF4376 PF14301.1 KRH92527.1 - 0.083 13.0 0.6 0.16 12.0 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Plectin PF00681.15 KRH92527.1 - 2.3 7.7 15.5 29 4.2 0.2 5.2 2 2 3 5 5 5 0 Plectin repeat rve PF00665.21 KRH92528.1 - 1.9e-18 66.7 0.0 7.5e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH92528.1 - 1.6e-10 40.7 0.1 3.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KRH92528.1 - 1.3e-05 25.5 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNase H Mad3_BUB1_I PF08311.7 KRH92528.1 - 0.032 14.0 0.5 1.3 8.8 0.1 2.9 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 RVT_thumb PF06817.9 KRH92528.1 - 0.034 13.7 0.1 0.13 11.8 0.0 2.0 1 1 0 1 1 1 0 Reverse transcriptase thumb domain BLYB PF05289.6 KRH92528.1 - 3.3 7.5 7.2 4.8 7.0 0.2 3.0 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein HRDC PF00570.18 KRH92530.1 - 0.045 13.4 0.1 0.13 11.9 0.1 1.9 1 0 0 1 1 1 0 HRDC domain TPR_21 PF09976.4 KRH92530.1 - 0.11 12.4 4.0 0.23 11.3 0.0 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KRH92531.1 - 1.2e-16 60.6 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RasGAP_C PF03836.10 KRH92532.1 - 0.097 12.3 3.4 0.32 10.6 2.4 1.9 1 1 0 1 1 1 0 RasGAP C-terminus Borrelia_lipo_2 PF06238.6 KRH92532.1 - 1 9.4 8.0 1.6 8.8 2.5 2.1 1 1 0 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein RVT_1 PF00078.22 KRH92533.1 - 1.6e-15 57.0 0.1 2.1e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aa_trans PF01490.13 KRH92534.1 - 2e-35 122.0 12.3 3.6e-35 121.2 8.5 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.10 KRH92534.1 - 3.9 7.7 6.8 16 5.7 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SSrecog PF03531.9 KRH92535.1 - 4.5e-26 91.5 1.2 6e-25 87.8 0.8 2.4 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KRH92535.1 - 2.8e-18 65.6 10.3 4.2e-16 58.6 0.5 3.6 4 0 0 4 4 4 2 Histone chaperone Rttp106-like Dala_Dala_lig_N PF01820.16 KRH92535.1 - 0.057 13.7 0.3 10 6.4 0.1 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus SRP54 PF00448.17 KRH92536.1 - 7.2e-35 120.2 0.0 1.3e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KRH92536.1 - 3.9e-05 23.9 0.0 3.9e-05 23.9 0.0 2.8 2 1 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 KRH92536.1 - 0.00099 18.5 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KRH92536.1 - 0.0024 17.7 5.7 0.0026 17.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KRH92536.1 - 0.0027 17.6 0.3 0.0027 17.6 0.2 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KRH92536.1 - 0.003 17.6 1.6 0.0064 16.6 0.1 2.2 2 1 1 3 3 3 1 AAA domain SRP54_N PF02881.14 KRH92536.1 - 0.0034 17.4 7.2 0.015 15.3 5.0 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 KRH92536.1 - 0.0043 17.0 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.18 KRH92536.1 - 0.009 15.4 0.2 0.009 15.4 0.1 3.0 1 1 2 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KRH92536.1 - 0.0094 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF303 PF03629.13 KRH92536.1 - 0.01 15.0 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF303) ArgK PF03308.11 KRH92536.1 - 0.054 12.2 0.0 0.12 11.1 0.0 1.7 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 KRH92536.1 - 0.079 13.7 6.6 0.13 13.0 0.0 3.2 2 1 1 3 3 3 0 AAA domain BLVR PF06375.6 KRH92536.1 - 2.4 7.9 28.4 0.022 14.5 9.6 3.0 2 1 1 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Nop PF01798.13 KRH92537.1 - 1.1e-35 122.0 0.2 2.4e-35 121.0 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KRH92537.1 - 8e-19 67.1 0.5 2e-18 65.9 0.3 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KRH92537.1 - 0.00042 20.4 0.6 0.0011 19.0 0.4 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Trypan_PARP PF05887.6 KRH92537.1 - 0.028 14.2 6.0 0.044 13.5 4.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Borrelia_P83 PF05262.6 KRH92538.1 - 0.39 8.9 26.4 0.47 8.6 18.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mem_trans PF03547.13 KRH92538.1 - 0.65 8.2 5.0 0.69 8.1 3.5 1.2 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 KRH92538.1 - 0.79 9.6 20.3 1 9.2 14.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Adaptin_binding PF10199.4 KRH92538.1 - 2.1 8.6 20.7 3.5 7.9 14.4 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SprA-related PF12118.3 KRH92538.1 - 2.1 7.6 21.8 2.6 7.3 15.1 1.1 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.4 KRH92538.1 - 9.4 4.3 15.9 11 4.0 11.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LMBR1 PF04791.11 KRH92538.1 - 9.5 4.6 11.0 12 4.3 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CTP_transf_2 PF01467.21 KRH92539.1 - 1.6e-17 63.9 0.1 2.8e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF3962 PF13111.1 KRH92539.1 - 0.014 14.8 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) EIAV_GP90 PF00971.13 KRH92539.1 - 0.023 13.1 0.1 0.038 12.4 0.1 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 FAD_syn PF06574.7 KRH92539.1 - 0.095 12.3 0.1 0.2 11.2 0.1 1.6 1 1 0 1 1 1 0 FAD synthetase Asp_protease_2 PF13650.1 KRH92542.1 - 1.4e-05 25.5 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH92542.1 - 2e-05 24.3 0.0 6.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 KRH92542.1 - 0.006 16.6 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Spuma_A9PTase PF03539.9 KRH92542.1 - 0.03 14.2 0.1 0.13 12.1 0.0 2.1 2 1 0 2 2 2 0 Spumavirus aspartic protease (A9) gag-asp_proteas PF13975.1 KRH92542.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_IS1595 PF12762.2 KRH92543.1 - 9.6e-30 103.4 0.2 3.4e-29 101.6 0.0 1.8 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 KRH92543.1 - 2.2e-05 23.8 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS66 family rve PF00665.21 KRH92543.1 - 0.0013 18.8 0.1 0.0033 17.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92543.1 - 0.0086 16.0 0.1 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 DDE domain DZR PF12773.2 KRH92544.1 - 0.017 14.9 5.3 0.017 14.9 3.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 KRH92544.1 - 0.021 14.3 0.3 0.021 14.3 0.2 3.7 4 1 1 5 5 5 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 KRH92544.1 - 1.5 8.0 18.1 4.7 6.5 5.3 3.6 2 2 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 KRH92544.1 - 4.8 6.7 16.8 4.8 6.8 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon domain Sec8_exocyst PF04048.9 KRH92545.1 - 2.2e-14 53.2 5.6 2.2e-14 53.2 3.8 3.2 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain JAB PF01398.16 KRH92546.1 - 1.2e-31 108.8 0.3 2.8e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KRH92546.1 - 1.5e-13 50.8 1.1 3.6e-13 49.6 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KRH92546.1 - 1.1e-08 34.5 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KRH92546.1 - 0.04 13.4 0.2 0.23 10.9 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF4181 PF13789.1 KRH92547.1 - 2.6 8.0 6.1 0.54 10.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) PPI_Ypi1 PF07491.6 KRH92550.1 - 3.8e-10 39.2 0.1 5.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor PipA PF07108.6 KRH92551.1 - 0.0022 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 PipA protein DUF2023 PF09633.5 KRH92551.1 - 0.016 15.1 0.1 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Codanin-1_C PF15296.1 KRH92553.1 - 0.079 12.8 2.9 0.095 12.5 0.2 2.2 2 1 0 2 2 2 0 Codanin-1 C-terminus ATP-synt_ab PF00006.20 KRH92554.1 - 3.7e-62 209.6 0.0 5.2e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KRH92554.1 - 2.5e-13 50.4 0.1 4.6e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KRH92554.1 - 3.2e-08 33.6 0.9 6.2e-08 32.7 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain rve_3 PF13683.1 KRH92555.1 - 9.2e-06 25.0 0.1 2.2e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve PF00665.21 KRH92555.1 - 5e-05 23.4 0.1 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1331 PF07048.6 KRH92556.1 - 4.6 6.7 13.0 3.8 7.0 0.2 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF1331) CPSase_L_D2 PF02786.12 KRH92557.1 - 1.1e-24 86.8 0.2 1.8e-21 76.4 0.0 3.0 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain TOM_sub5 PF15178.1 KRH92557.1 - 0.047 13.4 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog SMC_hinge PF06470.8 KRH92558.1 - 5.3e-08 32.8 0.1 2.7e-06 27.3 0.0 2.8 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain Creatinase_N PF01321.13 KRH92559.1 - 2.8e-15 56.9 0.0 5.1e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF740 PF05340.7 KRH92559.1 - 0.1 10.9 3.5 0.15 10.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RNase_Zc3h12a_2 PF14626.1 KRH92559.1 - 0.18 11.6 2.9 0.27 11.1 0.6 2.3 2 1 1 3 3 3 0 Zc3h12a-like Ribonuclease NYN domain PTPLA PF04387.9 KRH92562.1 - 1.3e-28 99.4 15.1 1e-27 96.6 10.4 1.9 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA tRNA-synt_1b PF00579.20 KRH92564.1 - 1.3e-56 191.8 0.1 1.5e-56 191.6 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Asp_protease_2 PF13650.1 KRH92565.1 - 0.0049 17.3 0.1 0.0074 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92565.1 - 0.018 14.8 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH92565.1 - 0.026 14.4 0.0 0.026 14.4 0.0 1.3 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.7 KRH92565.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 1 0 1 1 1 0 Putative peptidase (DUF1758) MSV199 PF10553.4 KRH92566.1 - 0.074 12.9 3.3 0.077 12.8 2.3 1.0 1 0 0 1 1 1 0 MSV199 domain zf-H2C2 PF09337.5 KRH92567.1 - 1.5e-05 24.2 0.6 1.5e-05 24.2 0.4 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger rve PF00665.21 KRH92567.1 - 8.7e-05 22.6 0.1 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.7 KRH92567.1 - 0.044 13.3 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) EmrE PF13536.1 KRH92568.1 - 2.4e-05 24.5 18.3 0.01 16.0 5.6 2.9 2 2 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KRH92568.1 - 0.00032 20.7 33.6 0.032 14.2 5.4 3.4 2 2 2 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KRH92568.1 - 0.0012 18.0 6.4 0.023 13.7 0.2 2.4 2 1 0 2 2 2 2 Nucleotide-sugar transporter ASFV_L11L PF05293.6 KRH92568.1 - 0.75 9.9 19.9 2.9 8.0 1.2 3.9 2 1 1 3 3 3 0 African swine fever virus (ASFV) L11L protein HTH_Tnp_IS630 PF01710.11 KRH92570.1 - 0.054 13.1 1.4 0.066 12.8 0.9 1.2 1 0 0 1 1 1 0 Transposase LRR_8 PF13855.1 KRH92571.1 - 3.7e-15 55.4 27.9 7.8e-09 35.1 4.8 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 KRH92571.1 - 1e-12 47.3 18.9 1.8e-08 33.7 3.4 3.0 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KRH92571.1 - 8.5e-09 34.2 16.9 0.00042 19.9 0.1 5.2 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 KRH92571.1 - 3.6e-05 23.3 10.6 0.028 14.4 0.2 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KRH92571.1 - 5.4e-05 22.7 8.6 0.1 12.8 0.1 4.9 5 0 0 5 5 5 1 Leucine rich repeat DUF4116 PF13475.1 KRH92571.1 - 2.8 7.5 8.3 62 3.1 5.7 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) Porin_3 PF01459.17 KRH92572.1 - 2.2e-06 27.1 0.9 0.00048 19.5 0.6 2.6 1 1 0 1 1 1 1 Eukaryotic porin LUC7 PF03194.10 KRH92573.1 - 0.094 12.2 0.9 0.1 12.0 0.6 1.0 1 0 0 1 1 1 0 LUC7 N_terminus BRICHOS PF04089.9 KRH92573.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 BRICHOS domain MFS_2 PF13347.1 KRH92574.1 - 0.00026 19.4 4.7 0.00026 19.4 3.3 3.9 3 1 0 4 4 4 2 MFS/sugar transport protein Retrotrans_gag PF03732.12 KRH92576.1 - 0.0027 17.7 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DRP PF06044.7 KRH92576.1 - 0.012 14.6 0.3 0.026 13.4 0.0 1.7 2 0 0 2 2 2 0 Dam-replacing family zf-ZPR1 PF03367.8 KRH92577.1 - 1.7e-05 24.0 0.5 3.5e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Elf1 PF05129.8 KRH92577.1 - 0.0026 17.4 5.0 1.6 8.4 0.3 3.1 2 1 1 3 3 3 3 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 KRH92577.1 - 0.041 13.2 0.5 0.088 12.1 0.3 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger FdhE PF04216.7 KRH92577.1 - 0.062 13.0 1.9 0.11 12.1 1.3 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation CpXC PF14353.1 KRH92577.1 - 0.4 10.6 2.9 1.9 8.4 2.0 2.1 1 1 0 1 1 1 0 CpXC protein Zn_Tnp_IS1595 PF12760.2 KRH92577.1 - 2.4 8.0 4.4 2.5 7.9 1.4 2.2 2 1 0 2 2 2 0 Transposase zinc-ribbon domain NTP_transf_2 PF01909.18 KRH92578.1 - 6.9e-08 32.7 0.0 2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KRH92578.1 - 4.5e-06 26.5 1.5 4.5e-06 26.5 1.0 2.7 2 1 0 2 2 2 1 Cid1 family poly A polymerase Pkinase PF00069.20 KRH92579.1 - 5e-55 186.4 0.6 9.1e-35 120.0 0.4 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92579.1 - 5.4e-30 104.3 0.4 2.5e-19 69.3 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KRH92579.1 - 0.0022 17.0 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4337 PF14235.1 KRH92579.1 - 0.05 13.4 2.0 0.58 9.9 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) APH PF01636.18 KRH92579.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Myosin_tail_1 PF01576.14 KRH92579.1 - 0.22 9.2 0.1 0.32 8.6 0.0 1.1 1 0 0 1 1 1 0 Myosin tail MSG PF02349.10 KRH92579.1 - 6.1 6.8 55.8 2 8.4 9.5 4.7 2 1 2 4 4 4 0 Major surface glycoprotein Lipase_3 PF01764.20 KRH92580.1 - 3.8e-07 29.7 0.0 8.1e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KRH92580.1 - 0.00019 21.0 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KRH92580.1 - 0.00055 19.7 0.6 0.0013 18.4 0.4 1.6 1 1 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KRH92580.1 - 0.00092 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KRH92580.1 - 0.0055 16.0 0.2 0.076 12.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 KRH92580.1 - 0.0057 16.2 0.8 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KRH92580.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 KRH92580.1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain DUF2305 PF10230.4 KRH92580.1 - 0.13 11.6 0.8 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) ApoB100_C PF12491.3 KRH92581.1 - 5.4 6.7 8.7 4.2 7.0 0.2 2.7 2 1 1 3 3 3 0 Apolipoprotein B100 C terminal DEAD PF00270.24 KRH92582.1 - 7.7e-25 87.3 0.0 6.8e-24 84.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TatD_DNase PF01026.16 KRH92583.1 - 7.4e-40 136.7 0.0 9.6e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase zf-RING_2 PF13639.1 KRH92585.1 - 5.1e-10 39.0 13.7 9.5e-10 38.1 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KRH92585.1 - 0.00012 22.1 12.4 0.00061 19.8 8.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KRH92585.1 - 0.00022 20.8 11.3 0.00039 20.0 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH92585.1 - 0.00045 20.1 15.7 0.00085 19.3 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH92585.1 - 0.0047 16.6 13.7 0.009 15.7 9.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KRH92585.1 - 0.0069 16.0 15.3 0.014 14.9 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KRH92585.1 - 0.15 11.8 9.5 1.3 8.9 6.6 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KRH92585.1 - 0.95 9.0 5.6 2.6 7.6 3.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KRH92585.1 - 4.6 7.0 10.6 13 5.5 7.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Ribosomal_L10 PF00466.15 KRH92587.1 - 1.2e-19 70.0 4.4 1.2e-19 70.0 3.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 CitX PF03802.9 KRH92587.1 - 0.0083 15.5 0.9 0.014 14.8 0.6 1.3 1 0 0 1 1 1 1 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF2620 PF10941.3 KRH92587.1 - 0.023 14.7 0.3 0.063 13.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DUF3903 PF13043.1 KRH92588.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) RE_AlwI PF09491.5 KRH92589.1 - 0.026 13.0 4.0 0.03 12.7 2.8 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease Peptidase_A4 PF01828.12 KRH92589.1 - 0.042 12.9 0.2 0.042 12.9 0.1 1.0 1 0 0 1 1 1 0 Peptidase A4 family ARS2 PF04959.8 KRH92589.1 - 0.73 9.9 3.4 0.77 9.9 2.3 1.0 1 0 0 1 1 1 0 Arsenite-resistance protein 2 NEMO PF11577.3 KRH92589.1 - 0.8 9.4 6.9 0.17 11.6 2.3 1.7 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO SAS4 PF15460.1 KRH92590.1 - 0.036 13.9 0.4 0.056 13.3 0.3 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 HTH_Crp_2 PF13545.1 KRH92590.1 - 0.18 11.5 0.6 0.64 9.8 0.1 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DDE_3 PF13358.1 KRH92591.1 - 2.5e-05 24.0 0.0 2.8e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3552 PF12072.3 KRH92593.1 - 0.00032 19.9 9.0 0.00056 19.1 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF1355 PF07090.6 KRH92593.1 - 0.08 12.2 0.2 1.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1355) DDE_3 PF13358.1 KRH92594.1 - 5.7e-15 55.3 0.0 6.4e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Img2 PF05046.9 KRH92595.1 - 0.023 14.9 0.3 0.074 13.2 0.2 1.9 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Acylphosphatase PF00708.13 KRH92595.1 - 0.047 13.7 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Acylphosphatase DUF3568 PF12092.3 KRH92595.1 - 0.18 11.5 3.9 3.4 7.4 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3568) Bap31 PF05529.7 KRH92596.1 - 0.4 10.1 5.9 0.51 9.7 4.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1673 PF07895.6 KRH92597.1 - 6.2 6.2 13.9 1.6 8.1 6.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Gpi16 PF04113.9 KRH92599.1 - 0.056 11.4 1.5 0.071 11.1 1.0 1.2 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Metallophos PF00149.23 KRH92600.1 - 1e-16 60.9 3.4 3.2e-16 59.3 2.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KRH92600.1 - 2e-14 53.6 0.1 7.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Herpes_LMP1 PF05297.6 KRH92600.1 - 5.8 5.7 7.9 7.8 5.3 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RRM_1 PF00076.17 KRH92601.1 - 6.4e-14 51.3 0.6 2.2e-13 49.6 0.1 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92601.1 - 1.5e-13 50.4 0.1 3.1e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH92601.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 KRH92601.1 - 2.1e-05 24.4 0.5 3.4e-05 23.8 0.4 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DED PF01335.16 KRH92601.1 - 0.18 11.9 2.7 0.46 10.6 1.9 1.7 1 0 0 1 1 1 0 Death effector domain Phage_GP20 PF06810.6 KRH92601.1 - 0.69 9.3 6.2 3.1 7.2 4.1 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Clat_adaptor_s PF01217.15 KRH92602.1 - 0.0001 22.0 3.5 0.00013 21.7 2.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tubulin PF00091.20 KRH92603.1 - 1.4e-65 221.1 0.1 2.4e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KRH92603.1 - 1.5e-21 76.7 0.3 2.7e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KRH92603.1 - 8.6e-06 25.7 0.1 4.9e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KRH92603.1 - 0.00038 19.9 0.0 0.00079 18.9 0.0 1.6 1 1 0 1 1 1 1 Tubulin domain Turandot PF07240.6 KRH92603.1 - 0.0032 16.9 0.5 0.023 14.1 0.2 2.3 2 0 0 2 2 2 1 Stress-inducible humoral factor Turandot Tubulin_2 PF13809.1 KRH92603.1 - 0.018 13.9 0.0 0.036 13.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DDE_Tnp_1_7 PF13843.1 KRH92605.1 - 4.5e-36 124.6 7.1 5.1e-36 124.4 4.9 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.1 KRH92606.1 - 1.2e-12 47.6 0.7 1.4e-12 47.3 0.5 1.1 1 0 0 1 1 1 1 Transposase IS4 KIP1 PF07765.7 KRH92606.1 - 0.019 14.8 0.2 0.042 13.7 0.1 1.7 1 0 0 1 1 1 0 KIP1-like protein CLTH PF10607.4 KRH92607.1 - 0.00021 20.9 4.9 0.00044 19.9 3.4 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Arf PF00025.16 KRH92608.1 - 8.7e-17 60.8 0.2 1.2e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KRH92608.1 - 2.4e-06 27.0 0.2 0.023 14.0 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.5 KRH92608.1 - 0.00074 18.7 0.0 0.0019 17.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KRH92608.1 - 0.0015 18.3 0.3 0.0038 16.9 0.2 1.7 1 1 1 2 2 2 1 Archaeal ATPase GTP_EFTU PF00009.22 KRH92608.1 - 0.0042 16.5 0.0 0.53 9.6 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KRH92608.1 - 0.0083 16.6 1.1 0.23 11.9 0.8 2.3 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KRH92608.1 - 0.024 14.5 0.4 0.081 12.8 0.3 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KRH92608.1 - 0.028 14.3 5.4 0.3 11.0 3.7 2.2 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KRH92608.1 - 0.034 13.4 0.0 2.1 7.6 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_14 PF13173.1 KRH92608.1 - 0.046 13.6 1.3 0.13 12.1 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 KRH92608.1 - 0.061 13.6 4.3 1.4 9.1 2.9 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KRH92608.1 - 0.081 13.2 0.1 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KRH92608.1 - 0.12 12.3 0.2 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KRH92608.1 - 0.13 12.1 0.0 6.4 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Gtr1_RagA PF04670.7 KRH92608.1 - 0.15 11.1 2.6 3.9 6.5 1.8 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RVT_1 PF00078.22 KRH92610.1 - 6.2e-15 55.1 0.0 1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3802 PF12290.3 KRH92610.1 - 0.099 12.9 0.2 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) RVT_1 PF00078.22 KRH92612.1 - 4.8e-13 48.9 0.0 8.2e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH92612.1 - 0.00038 20.3 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease BCD PF15461.1 KRH92616.1 - 0.033 13.6 1.7 0.038 13.3 1.2 1.0 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase DUF1700 PF08006.6 KRH92616.1 - 0.15 11.3 3.0 0.18 11.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4181 PF13789.1 KRH92616.1 - 0.92 9.4 8.7 1.2 9.1 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) AAA_23 PF13476.1 KRH92617.1 - 1.4e-18 67.9 23.7 1.4e-18 67.9 16.4 4.1 1 1 3 4 4 4 1 AAA domain SMC_N PF02463.14 KRH92617.1 - 8.4e-14 51.3 0.2 8.4e-14 51.3 0.2 4.8 3 1 3 6 6 6 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KRH92617.1 - 3.9e-07 29.4 0.0 9.1e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KRH92617.1 - 2.4e-05 24.4 21.2 2.4e-05 24.4 14.7 3.2 1 1 2 3 3 3 1 AAA domain AAA_13 PF13166.1 KRH92617.1 - 0.0005 18.6 0.1 0.0005 18.6 0.1 3.8 1 1 3 4 4 4 1 AAA domain ABC_tran PF00005.22 KRH92617.1 - 0.0014 18.9 0.8 0.0014 18.9 0.5 4.3 1 1 1 2 2 2 1 ABC transporter AAA_17 PF13207.1 KRH92617.1 - 0.011 16.5 0.2 0.011 16.5 0.1 4.2 1 1 1 2 2 2 0 AAA domain Acetyltransf_7 PF13508.1 KRH92618.1 - 0.023 14.8 0.1 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KRH92618.1 - 0.028 14.4 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.5 KRH92618.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein rve PF00665.21 KRH92620.1 - 2.2e-07 31.0 0.0 2.2e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.7 KRH92620.1 - 0.035 13.6 0.1 0.035 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RtcB PF01139.12 KRH92622.1 - 6e-51 173.7 0.0 6.7e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ParA PF10609.4 KRH92623.1 - 1.4e-16 60.1 0.0 3.7e-15 55.5 0.0 2.5 3 0 0 3 3 3 1 ParA/MinD ATPase like CbiA PF01656.18 KRH92623.1 - 2.1e-11 43.5 0.0 3.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KRH92623.1 - 1.6e-06 28.1 0.1 9.9e-05 22.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KRH92623.1 - 0.00015 20.8 2.7 0.0046 16.0 0.5 2.4 1 1 0 2 2 2 1 Anion-transporting ATPase KAP_NTPase PF07693.9 KRH92623.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.12 KRH92623.1 - 0.08 12.7 0.3 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_16 PF13191.1 KRH92623.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KRH92623.1 - 0.17 11.2 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 KRH92624.1 - 2 7.6 4.7 2.1 7.5 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CSD PF00313.17 KRH92626.1 - 6.9e-15 54.5 0.3 1.3e-13 50.4 0.0 2.3 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KRH92626.1 - 0.028 13.9 0.4 0.06 12.8 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain DSHCT PF08148.7 KRH92628.1 - 5.1e-47 159.4 0.1 9.2e-47 158.6 0.1 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DUF4163 PF13739.1 KRH92628.1 - 0.042 14.6 2.2 0.042 14.6 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) RecR PF02132.10 KRH92628.1 - 0.28 10.6 8.5 0.69 9.3 3.1 3.1 3 0 0 3 3 3 0 RecR protein Spt5-NGN PF03439.8 KRH92629.1 - 8.5e-14 51.0 0.6 1.5e-11 43.9 0.4 2.8 1 1 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KRH92629.1 - 1e-05 25.0 10.1 0.018 14.7 0.2 4.4 4 0 0 4 4 4 2 KOW motif NusG PF02357.14 KRH92629.1 - 0.0085 16.3 0.1 0.0085 16.3 0.0 2.8 3 0 0 3 3 3 1 Transcription termination factor nusG DUF3252 PF11623.3 KRH92629.1 - 0.052 12.9 0.4 3.1 7.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3252) Kinesin PF00225.18 KRH92630.1 - 2.7e-79 266.2 5.0 3.9e-79 265.7 3.4 1.2 1 0 0 1 1 1 1 Kinesin motor domain TFIIS_C PF01096.13 KRH92630.1 - 0.13 11.8 0.4 0.7 9.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) LNS2 PF08235.8 KRH92632.1 - 1.1e-38 132.2 0.1 2.5e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF2183 PF09949.4 KRH92632.1 - 0.0074 16.1 0.9 0.065 13.1 0.0 2.8 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2183) Hydrolase_6 PF13344.1 KRH92632.1 - 0.034 14.0 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA PF00004.24 KRH92633.1 - 4.8e-28 97.9 0.7 1.6e-27 96.2 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH92633.1 - 8.4e-06 25.9 0.0 2.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KRH92633.1 - 0.00019 21.1 0.1 0.0051 16.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KRH92633.1 - 0.00021 21.2 0.0 0.00058 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_10 PF12846.2 KRH92633.1 - 0.0014 18.1 0.9 0.49 9.7 0.0 2.6 3 0 0 3 3 3 2 AAA-like domain Zot PF05707.7 KRH92633.1 - 0.0034 16.8 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 KRH92633.1 - 0.004 16.5 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KRH92633.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KRH92633.1 - 0.011 15.7 0.1 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KRH92633.1 - 0.023 14.0 0.0 0.29 10.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KRH92633.1 - 0.028 15.2 1.9 0.15 12.8 0.3 2.8 2 1 0 2 2 2 0 AAA domain PHD PF00628.24 KRH92634.1 - 8.6e-08 31.7 7.9 1.4e-07 31.0 5.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KRH92634.1 - 0.00022 20.4 3.6 0.00041 19.5 2.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF2150 PF09920.4 KRH92634.1 - 0.0092 15.5 1.0 0.013 15.1 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2150) DDE_3 PF13358.1 KRH92636.1 - 5.9e-12 45.5 0.0 6.8e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH92637.1 - 1.5e-09 37.7 2.1 1.6e-09 37.6 0.1 1.9 1 1 1 2 2 2 1 Transposase HTH_7 PF02796.10 KRH92637.1 - 4.9e-05 23.0 0.6 0.01 15.6 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 KRH92637.1 - 0.00042 19.7 0.9 0.00093 18.6 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 KRH92637.1 - 0.0041 17.1 0.7 0.0066 16.4 0.1 1.6 2 0 0 2 2 2 1 HTH-like domain HTH_29 PF13551.1 KRH92637.1 - 0.0042 17.2 0.1 0.0056 16.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_33 PF13592.1 KRH92637.1 - 0.0054 16.2 0.1 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 KRH92637.1 - 0.012 16.4 0.0 0.035 14.9 0.0 1.7 1 1 1 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.5 KRH92637.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Mrr_N PF14338.1 KRH92638.1 - 0.077 13.0 1.1 0.092 12.8 0.7 1.1 1 0 0 1 1 1 0 Mrr N-terminal domain NEP PF10167.4 KRH92638.1 - 0.085 12.5 1.3 0.13 11.9 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein NAM PF02365.10 KRH92638.1 - 0.15 12.2 1.1 0.16 12.1 0.8 1.0 1 0 0 1 1 1 0 No apical meristem (NAM) protein DUF3835 PF12927.2 KRH92638.1 - 0.19 12.6 3.3 0.24 12.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) HGTP_anticodon2 PF12745.2 KRH92638.1 - 0.46 9.5 8.0 0.5 9.4 5.5 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF2011 PF09428.5 KRH92638.1 - 4.3 7.2 11.9 4.6 7.1 8.2 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Peptidase_S49_N PF08496.5 KRH92638.1 - 8.7 6.1 10.2 8.9 6.0 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-CCCH PF00642.19 KRH92639.1 - 1.3e-18 66.2 26.4 2e-10 40.0 5.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.4 KRH92639.1 - 2.8 7.8 9.2 5.6 6.8 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif RVT_1 PF00078.22 KRH92640.1 - 1.2e-23 83.5 0.1 2e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 KRH92640.1 - 3.1e-07 30.7 0.1 6.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KRH92640.1 - 4.7e-06 26.5 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH92640.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_thumb PF06817.9 KRH92640.1 - 6.3e-05 22.4 0.1 0.00019 20.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVP PF00077.15 KRH92640.1 - 0.0017 18.2 0.2 0.0047 16.8 0.2 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Rep_3 PF01051.16 KRH92640.1 - 0.002 17.7 0.6 0.49 9.9 0.1 2.6 1 1 1 2 2 2 2 Initiator Replication protein Sec62 PF03839.11 KRH92641.1 - 2.3e-27 95.9 1.4 2.7e-27 95.6 1.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.4 KRH92641.1 - 0.049 12.2 2.8 0.065 11.8 2.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plant_all_beta PF10532.4 KRH92641.1 - 0.15 12.1 2.4 0.23 11.5 1.4 1.5 1 1 0 1 1 1 0 Plant specific N-all beta domain DUF916 PF06030.7 KRH92641.1 - 0.25 11.1 6.6 0.36 10.6 4.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Claudin_3 PF06653.6 KRH92641.1 - 1.5 8.4 9.0 2.5 7.8 6.2 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like AAA_21 PF13304.1 KRH92643.1 - 1e-09 38.8 17.4 3.4e-06 27.2 12.0 2.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KRH92643.1 - 7.1e-07 28.6 4.2 1.1e-06 28.0 2.7 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KRH92643.1 - 0.0049 16.7 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF1268 PF06896.6 KRH92643.1 - 0.034 14.4 5.0 0.067 13.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1268) ABC_tran PF00005.22 KRH92643.1 - 0.079 13.2 3.2 0.99 9.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter PSCyt3 PF07627.6 KRH92643.1 - 0.12 12.2 0.3 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) RVP_2 PF08284.6 KRH92644.1 - 4.7e-07 29.8 0.0 6.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH92644.1 - 8.1e-05 22.3 0.0 0.00023 20.9 0.0 1.7 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH92644.1 - 0.00024 20.9 0.1 0.00059 19.7 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92644.1 - 0.0027 18.1 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 KRH92644.1 - 0.0067 15.9 0.1 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 KRH92645.1 - 2e-17 63.2 0.2 3.3e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phe_ZIP PF08916.6 KRH92647.1 - 7 7.0 12.3 6.4e+03 -2.5 8.6 3.5 1 1 0 1 1 1 0 Phenylalanine zipper S1FA PF04689.8 KRH92648.1 - 0.26 11.2 5.0 0.35 10.7 3.5 1.4 1 1 0 1 1 1 0 DNA binding protein S1FA Ufd2P_core PF10408.4 KRH92649.1 - 3.1e-33 114.9 21.4 4.5e-33 114.4 14.8 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KRH92649.1 - 6.9e-19 67.5 0.9 1.7e-18 66.3 0.6 1.7 1 0 0 1 1 1 1 U-box domain DUF1469 PF07332.6 KRH92651.1 - 1.3 8.7 3.3 1.4 8.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) YlaC PF10777.4 KRH92651.1 - 1.4 8.4 8.9 1.7 8.2 6.2 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC BolA PF01722.13 KRH92652.1 - 1.8e-08 34.2 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein UBA PF00627.26 KRH92653.1 - 1.4e-08 34.3 0.2 1.4e-08 34.3 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KRH92653.1 - 0.00021 20.8 0.8 0.00057 19.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 KRH92653.1 - 0.0087 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF849 PF05853.7 KRH92653.1 - 0.015 14.2 6.2 0.023 13.5 4.3 1.4 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) DUF2407_C PF13373.1 KRH92653.1 - 1.2 9.0 9.4 0.13 12.1 0.2 2.9 2 1 1 3 3 3 0 DUF2407 C-terminal domain Phage_Mu_Gam PF07352.7 KRH92656.1 - 0.32 10.5 3.3 0.85 9.1 2.3 1.8 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Pkinase PF00069.20 KRH92658.1 - 4.8e-34 117.6 0.4 5.7e-34 117.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92658.1 - 6.7e-15 54.8 0.1 7.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KRH92658.1 - 0.00047 19.5 0.1 0.0029 16.9 0.0 2.0 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 KRH92658.1 - 0.0013 17.7 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KRH92658.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.3 KRH92658.1 - 0.043 13.2 0.3 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Kdo PF06293.9 KRH92658.1 - 0.074 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1283 PF06932.6 KRH92662.1 - 0.014 15.3 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) eIF-1a PF01176.14 KRH92662.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 UCH PF00443.24 KRH92664.1 - 3.4e-09 36.2 15.4 3.4e-09 36.2 10.7 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3800 PF12686.2 KRH92664.1 - 0.00014 21.5 1.8 0.00014 21.5 1.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3800) Scramblase PF03803.10 KRH92664.1 - 0.0096 15.0 1.6 0.019 14.0 1.0 1.5 1 1 0 1 1 1 1 Scramblase CBM-like PF14683.1 KRH92665.1 - 0.011 15.4 0.2 0.013 15.1 0.1 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III Imm21 PF15569.1 KRH92665.1 - 0.017 14.8 1.3 0.044 13.5 0.0 2.1 1 1 1 2 2 2 0 Immunity protein 21 Collagen_bind PF05737.7 KRH92665.1 - 0.079 13.1 1.4 0.13 12.4 0.7 1.5 1 1 1 2 2 2 0 Collagen binding domain rve PF00665.21 KRH92666.1 - 1.9e-14 53.8 0.0 6.2e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92666.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 DDE domain RNase_H PF00075.19 KRH92666.1 - 0.015 15.6 0.1 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 RNase H DUF3290 PF11694.3 KRH92666.1 - 0.055 13.1 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Asp_protease_2 PF13650.1 KRH92667.1 - 1.4e-09 38.3 0.6 2.6e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH92667.1 - 2.8e-06 27.1 1.9 7.3e-06 25.8 0.6 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH92667.1 - 0.0025 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KRH92667.1 - 0.051 13.1 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 KRH92667.1 - 0.057 13.3 0.3 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Amastin PF07344.6 KRH92668.1 - 1.3 8.5 6.2 1.4 8.5 4.3 1.0 1 0 0 1 1 1 0 Amastin surface glycoprotein Proteasome PF00227.21 KRH92669.1 - 9.6e-43 145.6 0.3 1.2e-42 145.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit CTD_bind PF04818.8 KRH92671.1 - 2e-05 24.7 1.2 2e-05 24.7 0.8 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF3647 PF12363.3 KRH92671.1 - 0.014 15.5 1.9 0.023 14.8 0.0 2.2 2 0 0 2 2 2 0 Phage protein SAP30_Sin3_bdg PF13867.1 KRH92671.1 - 0.035 13.9 1.0 0.79 9.6 0.0 2.8 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3102 PF11300.3 KRH92671.1 - 3.7 7.5 8.0 0.2 11.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) DUF2604 PF10790.4 KRH92671.1 - 8.4 6.6 7.3 3.6 7.7 1.4 2.5 1 1 1 2 2 2 0 Protein of Unknown function (DUF2604) ABC2_membrane PF01061.19 KRH92672.1 - 0.52 9.4 9.7 0.55 9.3 6.7 1.0 1 0 0 1 1 1 0 ABC-2 type transporter Cytochrom_B_N PF00033.14 KRH92673.1 - 0.0078 15.5 0.2 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Glycophorin_A PF01102.13 KRH92673.1 - 0.049 13.3 0.2 1.5 8.5 0.0 2.8 2 1 0 2 2 2 0 Glycophorin A Atg14 PF10186.4 KRH92673.1 - 0.077 11.9 3.3 0.07 12.0 0.2 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF912 PF06024.7 KRH92673.1 - 0.15 12.0 17.4 0.13 12.2 0.7 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CD20 PF04103.10 KRH92673.1 - 1.2 9.0 5.6 24 4.8 0.1 3.4 3 0 0 3 3 3 0 CD20-like family UCH PF00443.24 KRH92677.1 - 4.6e-14 52.1 0.6 4.1e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH92677.1 - 0.0045 16.4 0.8 0.75 9.1 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Sulfate_transp PF00916.15 KRH92678.1 - 3.8e-15 55.6 15.2 5.4e-12 45.2 8.4 3.6 2 1 0 2 2 2 2 Sulfate transporter family AAA PF00004.24 KRH92679.1 - 4.2e-45 153.1 0.2 1.8e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH92679.1 - 4.9e-08 32.7 0.1 1.6e-07 31.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KRH92679.1 - 3.2e-07 30.4 0.0 8.2e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KRH92679.1 - 1.1e-06 28.7 1.0 0.00013 22.1 0.2 3.0 3 1 0 3 3 1 1 AAA domain AAA_16 PF13191.1 KRH92679.1 - 1.5e-06 28.3 0.2 5.5e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KRH92679.1 - 5.8e-05 23.9 0.4 0.0002 22.1 0.1 2.2 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KRH92679.1 - 6.2e-05 22.1 0.0 0.00015 20.8 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KRH92679.1 - 0.00015 21.4 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KRH92679.1 - 0.00015 22.0 0.7 0.0059 16.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KRH92679.1 - 0.00026 20.4 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KRH92679.1 - 0.00029 20.7 0.2 0.0039 17.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KRH92679.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KRH92679.1 - 0.0019 18.1 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KRH92679.1 - 0.002 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KRH92679.1 - 0.0022 16.8 0.2 0.0056 15.4 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 KRH92679.1 - 0.0022 17.6 0.0 0.0061 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KRH92679.1 - 0.0037 16.7 0.2 0.092 12.2 0.0 2.9 3 1 0 3 3 3 1 Sigma-54 interaction domain PhoH PF02562.11 KRH92679.1 - 0.0042 16.3 0.0 0.072 12.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DUF4201 PF13870.1 KRH92679.1 - 0.0047 16.3 4.2 0.0097 15.3 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Transposase_22 PF02994.9 KRH92679.1 - 0.0082 14.6 1.9 0.0082 14.6 1.3 1.6 2 0 0 2 2 2 1 L1 transposable element ATG16 PF08614.6 KRH92679.1 - 0.0083 15.9 1.8 0.017 14.9 1.3 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_25 PF13481.1 KRH92679.1 - 0.0086 15.4 0.1 0.067 12.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KRH92679.1 - 0.0089 15.2 0.1 0.023 13.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KRH92679.1 - 0.0093 15.5 0.1 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KRH92679.1 - 0.0099 15.5 0.0 0.53 9.9 0.0 2.3 1 1 1 2 2 2 1 NACHT domain DUF815 PF05673.8 KRH92679.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KaiC PF06745.8 KRH92679.1 - 0.011 14.8 1.7 0.039 13.0 0.0 2.6 2 1 0 3 3 3 0 KaiC DUF947 PF06102.7 KRH92679.1 - 0.014 15.1 2.2 0.033 14.0 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF947) TMF_TATA_bd PF12325.3 KRH92679.1 - 0.026 14.2 1.0 0.095 12.4 0.7 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1947 PF09183.5 KRH92679.1 - 0.032 13.9 0.3 0.092 12.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Parvo_NS1 PF01057.12 KRH92679.1 - 0.034 13.0 0.0 0.077 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.1 KRH92679.1 - 0.035 12.5 3.4 0.7 8.2 2.2 2.2 2 0 0 2 2 2 0 AAA domain RPA_C PF08784.6 KRH92679.1 - 0.039 14.3 0.1 0.55 10.6 0.0 2.4 2 0 0 2 2 2 0 Replication protein A C terminal RNA_helicase PF00910.17 KRH92679.1 - 0.041 14.0 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KRH92679.1 - 0.042 13.8 0.2 0.25 11.3 0.0 2.6 2 1 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KRH92679.1 - 0.13 12.5 0.7 0.57 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 KRH92679.1 - 0.13 11.8 0.8 0.63 9.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain DivIC PF04977.10 KRH92679.1 - 0.18 11.3 5.9 0.067 12.6 2.2 1.7 2 0 0 2 2 1 0 Septum formation initiator Laminin_II PF06009.7 KRH92679.1 - 0.47 10.2 6.5 1.9 8.2 1.1 2.8 3 0 0 3 3 2 0 Laminin Domain II Syja_N PF02383.13 KRH92680.1 - 2.9e-15 55.8 0.1 2.9e-15 55.8 0.0 2.6 2 1 0 2 2 2 1 SacI homology domain DUF240 PF03086.9 KRH92680.1 - 0.11 12.1 3.0 0.29 10.7 2.1 1.7 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 SNARE_assoc PF09335.6 KRH92680.1 - 0.59 10.3 7.3 1.5 9.0 5.0 1.6 1 1 0 1 1 1 0 SNARE associated Golgi protein RtcB PF01139.12 KRH92681.1 - 2.8e-32 112.2 0.0 2.8e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 tRNA-splicing ligase RtcB Gluconate_2-dh3 PF13618.1 KRH92681.1 - 0.19 11.8 1.9 4.8 7.3 1.3 2.3 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF2031 PF09592.5 KRH92681.1 - 0.33 10.0 12.3 0.55 9.3 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Spore_coat_CotO PF14153.1 KRH92681.1 - 1.3 8.4 15.4 6.3 6.2 10.6 1.9 2 0 0 2 2 2 0 Spore coat protein CotO DUF2431 PF10354.4 KRH92682.1 - 0.021 14.7 0.2 0.03 14.2 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) vATP-synt_E PF01991.13 KRH92683.1 - 0.046 12.9 0.2 0.072 12.3 0.2 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit rve PF00665.21 KRH92683.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain PAH PF02671.16 KRH92685.1 - 5.4e-13 48.3 0.0 1.3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat BBS2_Mid PF14783.1 KRH92687.1 - 0.029 14.1 2.7 0.26 11.0 0.1 3.2 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KRH92687.1 - 0.087 13.1 0.0 94 3.4 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain HSP70 PF00012.15 KRH92688.1 - 6.3e-156 519.7 5.9 7.6e-156 519.5 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KRH92688.1 - 3e-11 42.5 0.1 5.9e-07 28.3 0.0 2.6 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KRH92688.1 - 0.00028 20.7 4.3 0.035 13.9 0.3 3.7 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KRH92688.1 - 0.0003 20.4 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KRH92688.1 - 0.015 14.1 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KRH92688.1 - 0.039 13.0 1.1 7.4 5.5 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Pkinase PF00069.20 KRH92689.1 - 2e-31 109.1 4.5 3e-31 108.5 3.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92689.1 - 3.1e-18 65.7 0.2 4.9e-18 65.1 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH92689.1 - 0.00086 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seryl_tRNA_N PF02403.17 KRH92690.1 - 0.0076 16.2 2.0 0.0076 16.2 1.4 1.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WXG100 PF06013.7 KRH92690.1 - 0.015 15.2 0.2 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG RasGAP_C PF03836.10 KRH92690.1 - 0.018 14.6 2.5 0.019 14.6 1.7 1.0 1 0 0 1 1 1 0 RasGAP C-terminus AF0941-like PF14591.1 KRH92690.1 - 0.026 14.5 3.8 0.026 14.5 2.7 1.1 1 0 0 1 1 1 0 AF0941-like DUF4083 PF13314.1 KRH92690.1 - 0.03 14.1 1.1 0.032 14.0 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4083) MtrG PF04210.8 KRH92690.1 - 0.03 13.9 1.0 0.033 13.8 0.7 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G RmuC PF02646.11 KRH92690.1 - 0.063 12.1 0.8 0.061 12.1 0.5 1.0 1 0 0 1 1 1 0 RmuC family Sec2p PF06428.6 KRH92690.1 - 0.077 12.8 6.1 0.078 12.8 4.2 1.0 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ApoC-I PF04691.7 KRH92690.1 - 0.08 12.6 0.9 0.099 12.3 0.6 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) FlxA PF14282.1 KRH92690.1 - 0.081 12.8 3.2 0.083 12.8 2.2 1.1 1 0 0 1 1 1 0 FlxA-like protein MitMem_reg PF13012.1 KRH92690.1 - 0.11 12.5 1.4 0.11 12.5 1.0 1.0 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF948 PF06103.6 KRH92690.1 - 0.15 11.9 2.5 0.17 11.7 1.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1395 PF07160.7 KRH92690.1 - 0.15 11.5 1.8 0.15 11.4 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) THOC7 PF05615.8 KRH92690.1 - 0.16 12.2 4.3 0.16 12.2 3.0 1.0 1 0 0 1 1 1 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 KRH92690.1 - 0.18 11.5 4.5 0.2 11.3 3.1 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.4 KRH92690.1 - 0.2 11.2 3.3 0.26 10.8 2.3 1.3 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF4559 PF15112.1 KRH92690.1 - 0.21 10.6 4.5 0.22 10.6 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TBPIP PF07106.8 KRH92690.1 - 0.39 10.2 5.0 0.42 10.1 3.5 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 KRH92690.1 - 0.42 10.3 6.8 0.42 10.3 4.7 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1366 PF07104.6 KRH92690.1 - 0.42 10.2 5.2 0.47 10.0 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) ORF6C PF10552.4 KRH92690.1 - 0.45 10.2 3.8 0.46 10.2 2.6 1.1 1 0 0 1 1 1 0 ORF6C domain Erp_C PF06780.6 KRH92690.1 - 0.51 10.1 5.7 0.5 10.2 4.0 1.1 1 0 0 1 1 1 0 Erp protein C-terminus XhlA PF10779.4 KRH92690.1 - 0.62 10.0 3.8 0.68 9.8 2.6 1.2 1 0 0 1 1 1 0 Haemolysin XhlA YycC PF14174.1 KRH92690.1 - 2.9 7.6 5.7 49 3.6 3.9 2.0 1 1 0 1 1 1 0 YycC-like protein DUF2951 PF11166.3 KRH92690.1 - 3.5 7.5 6.8 3.7 7.4 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Med15_fungi PF05397.7 KRH92691.1 - 0.01 15.8 0.6 0.01 15.8 0.4 2.3 3 1 0 3 3 3 0 Mediator complex subunit 15 IncA PF04156.9 KRH92691.1 - 0.21 11.1 18.3 0.33 10.5 12.7 1.3 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.1 KRH92692.1 - 1.1e-27 97.1 5.8 3e-27 95.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KRH92692.1 - 1.3e-23 83.4 0.1 1.3e-23 83.4 0.1 2.3 3 0 0 3 3 3 1 AAA domain F-actin_cap_A PF01267.12 KRH92692.1 - 0.00034 19.7 5.1 0.00034 19.7 3.5 2.4 2 1 0 2 2 2 1 F-actin capping protein alpha subunit AAA_22 PF13401.1 KRH92693.1 - 0.00066 19.8 1.9 0.14 12.2 0.0 3.0 1 1 1 3 3 3 1 AAA domain AAA PF00004.24 KRH92693.1 - 0.0019 18.4 2.0 0.11 12.6 0.6 3.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KRH92693.1 - 0.0047 15.8 1.4 0.019 13.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 KRH92693.1 - 0.013 15.8 1.6 0.075 13.3 1.1 2.2 1 1 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.1 KRH92693.1 - 0.024 14.3 1.4 0.32 10.7 0.9 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain AAA_11 PF13086.1 KRH92693.1 - 0.033 13.7 5.4 0.059 12.9 3.8 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KRH92693.1 - 0.057 12.5 0.0 0.19 10.8 0.0 1.9 1 1 0 2 2 2 0 Zeta toxin cobW PF02492.14 KRH92693.1 - 0.088 12.2 1.0 1.2 8.5 0.7 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KRH92693.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 KRH92693.1 - 0.16 12.5 2.9 0.86 10.1 0.2 2.9 1 1 1 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 KRH92693.1 - 0.16 12.1 2.8 0.41 10.8 0.7 2.5 1 1 0 2 2 2 0 RNA helicase DUF2149 PF09919.4 KRH92693.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) AAA_14 PF13173.1 KRH92693.1 - 0.67 9.8 7.7 1.5 8.7 3.5 2.6 1 1 1 2 2 2 0 AAA domain LEH PF07858.7 KRH92694.1 - 0.07 13.1 0.1 0.07 13.1 0.1 1.0 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Peptidase_S8 PF00082.17 KRH92696.1 - 2.4e-47 161.4 0.1 2.4e-28 99.1 0.0 2.1 2 0 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.11 KRH92696.1 - 1.3e-07 32.1 0.5 3.6e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fijivirus_P9-2 PF06837.6 KRH92696.1 - 0.024 13.7 0.3 0.054 12.6 0.2 1.5 1 0 0 1 1 1 0 Fijivirus P9-2 protein Glyco_transf_15 PF01793.11 KRH92697.1 - 9.5e-112 373.2 14.9 1.2e-111 372.8 10.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TPR_11 PF13414.1 KRH92699.1 - 0.00053 19.5 0.0 0.043 13.4 0.1 3.0 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 KRH92699.1 - 0.00057 19.3 0.2 0.1 12.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat NMT1 PF09084.6 KRH92699.1 - 0.0019 17.8 0.1 0.0046 16.5 0.1 1.6 1 0 0 1 1 1 1 NMT1/THI5 like TPR_19 PF14559.1 KRH92699.1 - 0.024 14.9 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SAB PF04382.8 KRH92699.1 - 0.08 12.6 0.7 0.43 10.3 0.5 2.2 1 1 0 1 1 1 0 SAB domain TMP_2 PF06791.8 KRH92699.1 - 0.099 12.2 0.6 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein ATG_C PF09333.6 KRH92700.1 - 0.13 12.4 0.1 0.49 10.5 0.0 2.0 2 1 0 2 2 2 0 ATG C terminal domain HIT PF01230.18 KRH92701.1 - 4.5e-18 65.6 1.1 6.5e-18 65.0 0.8 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KRH92701.1 - 4e-06 27.0 0.8 5.9e-06 26.4 0.6 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KRH92701.1 - 0.12 12.0 0.7 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 WD40 PF00400.27 KRH92702.1 - 1.5e-14 53.2 3.9 6.8e-07 28.9 0.0 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat FAM150 PF15129.1 KRH92702.1 - 0.0053 16.6 0.7 0.77 9.6 0.0 2.6 2 1 1 3 3 3 2 FAM150 family NLE PF08154.7 KRH92702.1 - 0.017 15.1 0.1 0.049 13.6 0.1 1.8 1 0 0 1 1 1 0 NLE (NUC135) domain pRN1_helical PF13010.1 KRH92702.1 - 0.035 13.7 0.6 0.035 13.7 0.4 2.6 2 1 0 2 2 2 0 Primase helical domain Cadherin_2 PF08266.7 KRH92702.1 - 0.05 13.1 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Cadherin-like DDE_3 PF13358.1 KRH92703.1 - 3.8e-18 65.6 0.0 4.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP_bind_1 PF03029.12 KRH92704.1 - 1.4e-17 64.0 0.1 1.6e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KRH92704.1 - 0.0011 18.4 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 KRH92704.1 - 0.052 12.9 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Ras family NOG1 PF06858.9 KRH92704.1 - 0.07 13.0 0.6 0.16 11.9 0.4 1.6 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) GPAT_N PF14829.1 KRH92704.1 - 0.081 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Exo_endo_phos PF03372.18 KRH92705.1 - 1.2e-08 35.2 0.0 1.4e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RCC1 PF00415.13 KRH92706.1 - 1.5e-16 60.3 0.4 2.1e-05 24.6 0.0 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KRH92706.1 - 1.4e-09 37.3 2.4 0.09 12.4 0.1 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Pentapeptide_4 PF13599.1 KRH92707.1 - 8.4e-07 28.7 4.6 6.4e-06 25.8 3.2 2.5 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 KRH92707.1 - 4.9e-06 25.6 1.1 1.2e-05 24.3 0.4 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) GCS PF03074.11 KRH92708.1 - 1.1e-30 106.9 8.7 2.6e-30 105.7 5.8 1.7 1 1 1 2 2 2 1 Glutamate-cysteine ligase DUF3596 PF12167.3 KRH92709.1 - 0.11 12.0 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) PapD-like PF14874.1 KRH92709.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar-associated PapD-like rve PF00665.21 KRH92710.1 - 4e-22 78.5 0.0 1.2e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 KRH92710.1 - 0.0048 16.5 0.4 0.018 14.6 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 KRH92710.1 - 0.0055 16.1 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TFIIB PF00382.14 KRH92712.1 - 4.4e-37 125.7 0.4 3.9e-21 74.6 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KRH92712.1 - 7.8e-07 28.3 0.1 1.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Chlam_vir PF05475.6 KRH92712.1 - 0.00036 19.7 0.5 0.00062 18.9 0.4 1.5 1 0 0 1 1 1 1 Chlamydia virulence protein PGP3-D Cyclin_C PF02984.14 KRH92712.1 - 0.0024 17.7 0.0 0.75 9.7 0.0 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain HARE-HTH PF05066.8 KRH92712.1 - 0.0031 17.8 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 HB1, ASXL, restriction endonuclease HTH domain RB_B PF01857.15 KRH92712.1 - 0.016 14.7 0.4 0.038 13.5 0.1 1.6 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain DUF4370 PF14290.1 KRH92712.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) DUF4145 PF13643.1 KRH92713.1 - 0.29 10.9 2.7 1.3 8.9 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) RVT_1 PF00078.22 KRH92714.1 - 4.3e-12 45.8 0.0 5e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_M48 PF01435.13 KRH92716.1 - 2.3e-08 33.9 0.0 5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_A2B PF12384.3 KRH92717.1 - 2.4e-06 27.0 0.0 3.9e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 KRH92717.1 - 3e-06 27.6 0.0 0.00012 22.4 0.0 2.1 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92717.1 - 2.4e-05 24.0 0.0 6.3e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH92717.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH92717.1 - 0.075 12.9 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4145 PF13643.1 KRH92717.1 - 5.2 6.9 7.9 12 5.8 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4145) RVT_1 PF00078.22 KRH92718.1 - 2.2e-23 82.7 0.8 5.1e-23 81.5 0.6 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH92718.1 - 0.0053 16.2 0.1 0.016 14.8 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain SHMT PF00464.14 KRH92719.1 - 3e-151 503.3 0.1 3.5e-151 503.1 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KRH92719.1 - 0.031 13.2 0.1 0.048 12.6 0.1 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Lipase_GDSL_3 PF14606.1 KRH92720.1 - 0.065 12.9 2.2 0.17 11.5 0.1 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family zf-RING_2 PF13639.1 KRH92721.1 - 2.7e-13 49.5 9.8 4.1e-13 48.9 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KRH92721.1 - 9.9e-09 34.7 9.9 1.7e-08 33.9 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH92721.1 - 3.3e-07 30.2 10.7 5.4e-07 29.5 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH92721.1 - 8.1e-07 28.6 8.6 1.3e-06 28.0 6.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH92721.1 - 1e-06 28.3 9.1 1.6e-06 27.7 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KRH92721.1 - 5.6e-06 26.3 9.3 1.4e-05 25.1 6.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KRH92721.1 - 3.6e-05 23.5 1.7 6.8e-05 22.6 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KRH92721.1 - 0.02 14.4 8.3 0.034 13.7 5.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KRH92721.1 - 0.086 12.8 8.1 0.53 10.2 5.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KRH92721.1 - 0.4 10.7 9.7 1.3 9.1 6.8 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KRH92721.1 - 0.79 9.7 10.1 1.5 8.8 7.0 1.5 1 1 0 1 1 1 0 RING-like domain zf-RING_6 PF14835.1 KRH92721.1 - 0.93 9.3 5.0 5.8 6.7 3.6 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KRH92721.1 - 1.2 8.7 5.5 4.3 6.9 3.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KRH92721.1 - 1.5 8.6 8.1 3.6 7.3 2.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 KRH92721.1 - 3.1 7.5 9.2 6.1 6.6 6.3 1.5 1 0 0 1 1 1 0 PHD-finger TLC PF03219.9 KRH92723.1 - 5.3e-55 186.8 25.8 7.5e-55 186.3 17.9 1.2 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF1283 PF06932.6 KRH92724.1 - 0.013 15.5 0.1 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) FeThRed_A PF02941.10 KRH92724.1 - 0.11 12.4 0.3 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain rve_3 PF13683.1 KRH92725.1 - 2.3e-05 23.8 0.0 4.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 KRH92725.1 - 2.3e-05 24.4 0.1 0.00031 20.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92725.1 - 0.014 15.3 2.2 0.062 13.2 0.1 2.0 1 1 1 2 2 2 0 DDE domain KIF1B PF12423.3 KRH92726.1 - 0.037 14.0 1.9 0.079 13.0 1.3 1.7 1 1 0 1 1 1 0 Kinesin protein 1B PBP_sp32 PF07222.7 KRH92726.1 - 0.6 9.2 5.7 0.86 8.7 4.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sad1_UNC PF07738.8 KRH92727.1 - 2.9e-09 36.8 1.8 4.4e-09 36.2 1.3 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal C4 PF01413.14 KRH92730.1 - 0.031 14.1 5.3 0.26 11.1 1.3 2.1 1 1 1 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen Retrotrans_gag PF03732.12 KRH92731.1 - 0.014 15.4 0.2 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein PNMA PF14893.1 KRH92731.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 PNMA Pro_isomerase PF00160.16 KRH92732.1 - 2.5e-36 125.2 2.3 3e-36 124.9 1.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rdx PF10262.4 KRH92732.1 - 0.046 13.7 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 Rdx family DnaB_C PF03796.10 KRH92734.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NPV_P10 PF05531.7 KRH92737.1 - 5.6 7.2 21.4 2 8.7 0.1 5.1 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Ribosomal_S3_C PF00189.15 KRH92739.1 - 9.8e-12 44.9 3.3 1.9e-11 43.9 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain HATPase_c_3 PF13589.1 KRH92740.1 - 4.2e-15 55.5 1.6 5.9e-15 55.1 1.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KRH92740.1 - 4.8e-07 29.4 0.6 1.2e-06 28.2 0.4 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L11_N PF03946.9 KRH92741.1 - 4.1e-12 45.3 0.1 7.2e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KRH92741.1 - 1.8e-09 37.5 0.2 3.7e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF4380 PF14315.1 KRH92742.1 - 0.092 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Helicase_C PF00271.26 KRH92743.1 - 3.6e-18 65.1 0.0 4.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Topoisom_bac PF01131.15 KRH92744.1 - 3.9e-57 193.9 0.1 2.5e-32 112.2 0.0 2.4 1 1 1 2 2 2 2 DNA topoisomerase zf-GRF PF06839.7 KRH92744.1 - 4.1e-08 33.0 6.4 4.1e-08 33.0 4.5 2.6 2 0 0 2 2 2 1 GRF zinc finger Lamprin PF06403.6 KRH92744.1 - 1 9.1 8.6 1.6 8.4 5.9 1.2 1 0 0 1 1 1 0 Lamprin Guanylate_kin PF00625.16 KRH92745.1 - 6e-36 123.6 1.2 6.8e-36 123.4 0.8 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KRH92745.1 - 7.2e-09 36.0 3.6 9e-09 35.7 2.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH92745.1 - 1.1e-06 29.4 1.6 1.9e-06 28.6 1.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KRH92745.1 - 0.00065 19.6 0.4 0.001 18.9 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KRH92745.1 - 0.00082 19.2 0.1 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KRH92745.1 - 0.0015 17.5 0.4 0.0024 16.8 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 KRH92745.1 - 0.0018 18.6 4.2 0.011 16.0 2.9 2.1 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KRH92745.1 - 0.0019 18.1 0.1 0.0021 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KRH92745.1 - 0.002 17.6 0.8 0.0049 16.3 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KRH92745.1 - 0.0025 17.3 0.1 0.0081 15.7 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KRH92745.1 - 0.0028 17.1 0.2 0.55 9.6 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KRH92745.1 - 0.0062 16.6 0.1 0.044 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KRH92745.1 - 0.0079 15.5 2.2 0.55 9.5 1.6 2.2 1 1 0 1 1 1 1 Thymidylate kinase DUF258 PF03193.11 KRH92745.1 - 0.0094 15.1 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KRH92745.1 - 0.0095 15.6 0.2 0.016 14.9 0.1 1.7 1 1 0 1 1 1 1 NTPase KTI12 PF08433.5 KRH92745.1 - 0.0096 15.1 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.4 KRH92745.1 - 0.012 14.3 0.1 0.018 13.6 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Miro PF08477.8 KRH92745.1 - 0.012 16.1 0.3 0.046 14.2 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein MobB PF03205.9 KRH92745.1 - 0.014 15.0 0.4 0.024 14.3 0.2 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 KRH92745.1 - 0.016 14.3 0.5 0.023 13.8 0.3 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 KRH92745.1 - 0.02 14.3 0.7 0.033 13.6 0.6 1.5 1 1 0 1 1 1 0 AAA-like domain Cytidylate_kin2 PF13189.1 KRH92745.1 - 0.027 14.3 4.6 0.23 11.3 3.2 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family NACHT PF05729.7 KRH92745.1 - 0.029 14.0 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ADK PF00406.17 KRH92745.1 - 0.029 14.2 0.2 0.72 9.7 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase DUF815 PF05673.8 KRH92745.1 - 0.032 13.1 0.1 0.074 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KRH92745.1 - 0.044 13.2 0.7 0.089 12.2 0.3 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 KRH92745.1 - 0.046 12.6 0.3 0.11 11.4 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KRH92745.1 - 0.05 13.7 1.4 0.35 11.0 1.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KRH92745.1 - 0.062 12.3 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 KRH92745.1 - 0.11 12.2 2.6 0.54 10.0 1.8 1.9 1 1 0 1 1 1 0 Dynamin family CPT PF07931.7 KRH92745.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 KRH92745.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.1 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 KRH92745.1 - 0.13 12.1 5.0 0.16 11.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 KRH92745.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KRH92745.1 - 0.42 10.2 9.0 4.9 6.7 6.2 2.1 1 1 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 KRH92745.1 - 0.55 9.9 7.4 0.16 11.7 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 DUF4105 PF13387.1 KRH92749.1 - 0.0001 21.5 1.4 0.00021 20.5 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) FliL PF03748.9 KRH92749.1 - 0.009 15.9 1.1 0.009 15.9 0.8 2.4 2 1 0 2 2 2 1 Flagellar basal body-associated protein FliL ATP-synt_ab PF00006.20 KRH92750.1 - 8e-112 371.9 0.0 1.3e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KRH92750.1 - 1.6e-17 63.9 0.3 3.4e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KRH92750.1 - 2.4e-11 43.6 0.4 5.8e-11 42.4 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 KRH92750.1 - 0.062 13.1 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Metallophos PF00149.23 KRH92751.1 - 3.7e-44 150.5 0.3 4.7e-44 150.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PMM PF03332.8 KRH92752.1 - 0.042 13.4 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase HTH_Tnp_Tc3_2 PF01498.13 KRH92753.1 - 3.1e-10 39.9 6.2 5.3e-09 35.9 1.7 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 KRH92753.1 - 4.6e-07 29.9 0.4 6.3e-07 29.5 0.3 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KRH92753.1 - 1.3e-05 25.9 1.3 3.6e-05 24.4 0.6 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.7 KRH92753.1 - 0.0001 21.8 1.0 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_21 PF13276.1 KRH92753.1 - 0.0044 16.9 0.5 0.071 13.1 0.0 2.3 2 0 0 2 2 2 1 HTH-like domain HTH_7 PF02796.10 KRH92753.1 - 0.01 15.6 0.8 0.38 10.6 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase Sigma70_ECF PF07638.6 KRH92753.1 - 0.042 13.5 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor PAX PF00292.13 KRH92753.1 - 0.13 11.9 0.9 0.19 11.4 0.6 1.3 1 1 0 1 1 1 0 'Paired box' domain HTH_23 PF13384.1 KRH92753.1 - 0.14 11.8 0.3 0.14 11.8 0.2 1.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_26 PF13443.1 KRH92753.1 - 0.18 12.0 1.1 5.3 7.3 0.0 3.3 2 2 1 3 3 3 0 Cro/C1-type HTH DNA-binding domain NOSIC PF08060.8 KRH92754.1 - 0.059 13.1 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 NOSIC (NUC001) domain DDE_Tnp_IS1595 PF12762.2 KRH92755.1 - 1.7e-26 92.8 0.1 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH92755.1 - 0.72 9.3 3.8 0.38 10.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) NIF PF03031.13 KRH92756.1 - 7.3e-18 64.7 1.9 6.1e-16 58.4 0.1 2.8 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase Herpes_LMP1 PF05297.6 KRH92756.1 - 0.081 11.8 2.3 0.13 11.1 1.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_L3 PF00297.17 KRH92757.1 - 9.7e-07 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Cpn60_TCP1 PF00118.19 KRH92759.1 - 9.7e-59 199.2 19.3 2.4e-54 184.7 10.6 2.4 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3354 PF11834.3 KRH92759.1 - 0.037 13.6 0.3 3.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) Asp_protease_2 PF13650.1 KRH92760.1 - 7e-09 36.0 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92760.1 - 3.7e-07 29.8 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH92760.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH92760.1 - 9e-05 22.3 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH92760.1 - 0.037 13.5 0.2 0.093 12.3 0.1 1.7 1 1 0 1 1 1 0 Aspartyl protease Haemocyan_bet_s PF14830.1 KRH92762.1 - 0.065 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Haemocyanin beta-sandwich DDE_3 PF13358.1 KRH92763.1 - 7.1e-05 22.5 0.0 8.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Tyrosinase PF00264.15 KRH92765.1 - 4.5e-29 102.2 1.0 1.2e-28 100.7 0.7 1.7 1 0 0 1 1 1 1 Common central domain of tyrosinase Asp_protease_2 PF13650.1 KRH92767.1 - 9.7e-07 29.2 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92767.1 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH92767.1 - 9.9e-06 25.4 0.1 2.8e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 KRH92767.1 - 9.7e-05 21.8 0.5 0.0047 16.3 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 KRH92767.1 - 0.00013 21.9 0.1 0.00024 21.0 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH92767.1 - 0.00034 20.1 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Metallophos PF00149.23 KRH92768.1 - 7.2e-31 107.1 0.6 1e-30 106.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF221 PF02714.10 KRH92770.1 - 8.6e-62 208.8 29.2 1.3e-61 208.3 20.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 Occludin_ELL PF07303.8 KRH92770.1 - 0.032 14.9 0.9 0.032 14.9 0.6 2.4 3 1 0 3 3 3 0 Occludin homology domain Mif2_N PF15624.1 KRH92770.1 - 0.051 14.1 0.7 0.1 13.1 0.5 1.4 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DivIC PF04977.10 KRH92770.1 - 0.74 9.3 5.4 0.22 11.0 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Pox_A31 PF05771.6 KRH92771.1 - 0.15 11.8 2.4 0.31 10.8 0.2 2.4 2 1 0 2 2 2 0 Poxvirus A31 protein ER_lumen_recept PF00810.13 KRH92771.1 - 8.8 6.8 14.8 0.31 11.5 4.6 2.2 1 1 0 2 2 2 0 ER lumen protein retaining receptor Piwi PF02171.12 KRH92774.1 - 7e-71 238.6 6.0 9.1e-70 235.0 4.2 2.1 1 1 0 1 1 1 1 Piwi domain MBOAT PF03062.14 KRH92777.1 - 4.8e-13 48.9 46.5 4.8e-13 48.9 32.2 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KRH92777.1 - 9.9e-05 22.3 6.0 0.00029 20.8 4.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4179 PF13786.1 KRH92777.1 - 0.029 14.5 4.5 0.056 13.6 1.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) B-block_TFIIIC PF04182.7 KRH92778.1 - 0.0013 18.5 0.1 0.0052 16.5 0.1 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Sel1 PF08238.7 KRH92779.1 - 1.7e-97 317.6 31.5 1e-09 38.7 0.2 13.8 14 0 0 14 14 14 13 Sel1 repeat TPR_11 PF13414.1 KRH92779.1 - 4.5e-08 32.6 33.2 0.048 13.3 3.3 7.3 3 2 4 7 7 7 5 TPR repeat TPR_17 PF13431.1 KRH92779.1 - 0.00015 21.6 16.7 5.8 7.3 0.1 9.6 9 1 1 10 10 10 2 Tetratricopeptide repeat COG5 PF10392.4 KRH92780.1 - 0.0011 18.9 0.1 0.0014 18.5 0.1 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Phi-29_GP4 PF05464.6 KRH92780.1 - 0.36 10.7 3.0 0.35 10.7 0.3 1.8 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) zf-CCHC PF00098.18 KRH92781.1 - 2.1e-07 30.5 2.1 2.1e-07 30.5 1.4 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 KRH92781.1 - 0.014 15.0 1.2 0.035 13.7 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 KRH92781.1 - 2 8.1 8.0 2.2 8.0 2.3 2.7 2 1 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 KRH92781.1 - 3.5 6.9 7.3 0.81 8.9 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain tRNA-synt_1 PF00133.17 KRH92782.1 - 4.5e-135 450.9 4.5 4.5e-135 450.9 3.1 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KRH92782.1 - 4.3e-14 51.9 14.0 9.9e-12 44.2 0.7 3.4 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KRH92782.1 - 4.4e-09 35.8 7.3 1.3e-07 31.0 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 KRH92782.1 - 0.00076 18.3 0.0 0.00076 18.3 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 KRH92782.1 - 1.3 7.6 16.0 1.1 7.8 0.0 3.4 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain DUF1730 PF08331.5 KRH92783.1 - 0.028 14.0 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) FliD_N PF02465.13 KRH92783.1 - 0.048 14.0 0.2 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Imm5 PF14423.1 KRH92783.1 - 0.29 10.7 2.2 0.34 10.4 0.8 1.5 1 1 1 2 2 2 0 Immunity protein Imm5 SPT16 PF08644.6 KRH92784.1 - 8.4e-17 61.4 11.7 8.4e-17 61.4 8.1 4.4 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 KRH92784.1 - 5.8e-15 55.0 1.5 5.8e-15 55.0 1.1 4.6 4 2 0 4 4 4 1 Histone chaperone Rttp106-like PAPS_reduct PF01507.14 KRH92784.1 - 0.42 10.3 7.5 6.5 6.5 0.2 2.7 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family CTP_transf_2 PF01467.21 KRH92785.1 - 9e-22 77.8 0.4 1.7e-15 57.4 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KRH92785.1 - 2.4e-06 27.2 1.3 0.098 12.2 0.1 3.0 3 0 0 3 3 3 2 FAD synthetase Pantoate_ligase PF02569.10 KRH92785.1 - 0.042 12.5 0.0 5.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase DUF1082 PF06449.6 KRH92786.1 - 2.1 8.3 5.1 13 5.8 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) EssA PF10661.4 KRH92787.1 - 0.16 11.6 1.1 0.15 11.7 0.8 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA UQ_con PF00179.21 KRH92788.1 - 4.8e-46 155.6 0.1 5.5e-46 155.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KRH92788.1 - 9.2e-06 25.4 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Myb_DNA-bind_6 PF13921.1 KRH92789.1 - 0.00044 20.3 0.3 0.00095 19.2 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KRH92789.1 - 0.00075 19.4 0.5 0.0015 18.5 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3492 PF11997.3 KRH92790.1 - 0.056 12.9 0.2 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) RVT_1 PF00078.22 KRH92791.1 - 6.4e-24 84.5 1.3 8.7e-24 84.0 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH92791.1 - 7.9e-11 41.7 0.3 3.4e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92791.1 - 4e-06 27.2 0.0 8.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Spuma_A9PTase PF03539.9 KRH92791.1 - 2.7e-05 24.1 0.4 6.8e-05 22.8 0.3 1.7 1 0 0 1 1 1 1 Spumavirus aspartic protease (A9) RVP_2 PF08284.6 KRH92791.1 - 6.8e-05 22.8 0.1 0.00014 21.7 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH92791.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A3 PF02160.10 KRH92791.1 - 0.00093 18.8 0.4 0.00093 18.8 0.3 2.1 2 0 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) Asp_protease PF09668.5 KRH92791.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp PF00026.18 KRH92791.1 - 0.073 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic aspartyl protease GRAB PF10375.4 KRH92792.1 - 0.11 12.2 3.0 8.4 6.3 0.4 3.2 3 0 0 3 3 3 0 GRIP-related Arf-binding domain zf-RING_5 PF14634.1 KRH92793.1 - 0.0027 17.4 4.7 0.0045 16.6 3.2 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KRH92793.1 - 0.01 15.6 3.4 0.016 15.0 2.4 1.5 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KRH92793.1 - 0.02 14.9 4.7 0.035 14.1 3.3 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BDV_G PF06208.6 KRH92793.1 - 0.073 11.9 0.5 0.073 11.9 0.3 1.0 1 0 0 1 1 1 0 Borna disease virus G protein Cript PF10235.4 KRH92793.1 - 0.073 13.4 4.0 0.079 13.3 2.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-RING_UBOX PF13445.1 KRH92793.1 - 0.096 12.4 2.4 0.18 11.5 1.7 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 KRH92793.1 - 0.12 12.0 4.8 0.39 10.4 3.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KRH92793.1 - 0.21 11.5 6.2 0.33 10.8 4.3 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING MCM PF00493.18 KRH92794.1 - 5.3e-43 147.0 0.1 9.9e-21 73.8 0.0 2.9 2 1 0 2 2 2 2 MCM2/3/5 family AAA_16 PF13191.1 KRH92794.1 - 0.0028 17.6 0.0 0.0098 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KRH92794.1 - 0.017 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KRH92794.1 - 0.021 13.9 0.1 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CH PF00307.26 KRH92795.1 - 5.1e-24 84.3 8.4 3.1e-13 49.7 0.2 3.5 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KRH92795.1 - 1.5e-07 30.9 3.3 0.00059 19.4 0.0 3.6 4 0 0 4 4 4 2 CAMSAP CH domain MMR_HSR1 PF01926.18 KRH92796.1 - 2.2e-11 43.7 0.7 1.4e-10 41.1 0.5 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KRH92796.1 - 0.0024 18.3 0.1 0.0077 16.7 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KRH92796.1 - 0.0032 16.7 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.17 KRH92796.1 - 0.019 15.1 0.2 0.076 13.1 0.1 2.1 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.4 KRH92796.1 - 0.04 13.4 0.1 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 KRH92796.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KRH92796.1 - 0.11 12.3 2.9 0.36 10.6 2.0 2.0 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.1 KRH92796.1 - 0.22 11.8 2.7 0.27 11.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain Pox_L3_FP4 PF03339.9 KRH92797.1 - 0.037 12.4 1.7 0.063 11.7 0.6 1.6 1 1 1 2 2 2 0 Poxvirus L3/FP4 protein DUF2387 PF09526.5 KRH92797.1 - 0.09 12.7 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Peptidase_C48 PF02902.14 KRH92798.1 - 7.3e-09 35.5 2.4 2.3e-08 33.9 1.6 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KRH92798.1 - 6.8e-05 21.5 0.7 6.8e-05 21.5 0.5 1.6 1 1 0 1 1 1 1 Vaccinia virus I7 processing peptidase UCH PF00443.24 KRH92799.1 - 4.4e-15 55.5 8.3 7.3e-15 54.7 5.7 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH92799.1 - 5e-08 32.7 18.2 6.6e-08 32.3 10.3 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HTH_Tnp_ISL3 PF13542.1 KRH92800.1 - 0.099 11.8 0.0 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Chal_sti_synt_C PF02797.10 KRH92800.1 - 1.3 8.9 9.1 19 5.1 0.4 4.4 3 2 2 5 5 5 0 Chalcone and stilbene synthases, C-terminal domain eRF1_2 PF03464.10 KRH92801.1 - 1e-32 113.2 0.1 2.6e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_1 PF03463.10 KRH92801.1 - 2.2e-21 75.8 0.0 5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KRH92801.1 - 5.1e-21 75.0 0.9 1.2e-20 73.8 0.6 1.7 1 0 0 1 1 1 1 eRF1 domain 3 Far-17a_AIG1 PF04750.9 KRH92802.1 - 6.4e-16 58.1 13.8 8e-16 57.7 9.6 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Epiglycanin_C PF14654.1 KRH92802.1 - 2 8.4 4.0 6.1 6.9 0.1 3.1 1 1 2 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region rve PF00665.21 KRH92803.1 - 8.9e-07 29.0 0.0 9.5e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92803.1 - 0.0012 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Acylphosphatase PF00708.13 KRH92803.1 - 0.086 12.9 0.0 0.093 12.8 0.0 1.0 1 0 0 1 1 1 0 Acylphosphatase Cecropin PF00272.14 KRH92803.1 - 0.17 11.4 0.7 0.26 10.8 0.5 1.2 1 0 0 1 1 1 0 Cecropin family HTH_32 PF13565.1 KRH92804.1 - 0.53 11.1 3.2 0.91 10.3 0.1 2.1 1 1 1 2 2 2 0 Homeodomain-like domain RVT_1 PF00078.22 KRH92805.1 - 1.1e-20 73.9 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.9 KRH92805.1 - 0.0056 16.2 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Ala_racemase_N PF01168.15 KRH92805.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain IMS PF00817.15 KRH92806.1 - 1.1e-28 99.8 0.0 3.7e-28 98.1 0.0 1.8 1 1 0 1 1 1 1 impB/mucB/samB family NTPase_P4 PF11602.3 KRH92806.1 - 0.039 12.9 0.1 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF1805 PF08827.6 KRH92806.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF2404 PF10296.4 KRH92807.1 - 7.9e-05 22.7 0.3 0.00032 20.7 0.1 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ribosomal_L19 PF01245.15 KRH92807.1 - 0.062 13.0 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L19 zf-CCCH PF00642.19 KRH92808.1 - 0.0024 17.4 2.4 0.0067 16.0 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CHC2 PF01807.15 KRH92808.1 - 0.18 11.3 1.2 0.24 10.9 0.8 1.3 1 0 0 1 1 1 0 CHC2 zinc finger Myticin-prepro PF10690.4 KRH92808.1 - 1 9.4 5.2 0.91 9.5 3.3 1.3 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel VWC PF00093.13 KRH92808.1 - 5.8 7.1 9.0 1.5 8.9 3.9 1.8 2 0 0 2 2 2 0 von Willebrand factor type C domain DUF1289 PF06945.8 KRH92808.1 - 8.8 5.8 7.6 3.8 7.0 3.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1289) HTH_Crp_2 PF13545.1 KRH92809.1 - 0.014 15.1 1.3 0.037 13.8 0.3 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain SAS4 PF15460.1 KRH92809.1 - 0.026 14.3 0.1 0.039 13.8 0.1 1.4 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 RNA_pol_Rpb1_2 PF00623.15 KRH92811.1 - 0.36 10.7 5.0 0.32 10.9 1.9 2.0 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 2 OS-D PF03392.8 KRH92811.1 - 0.55 10.2 8.4 0.15 12.0 3.0 2.1 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D DltD_M PF04918.7 KRH92811.1 - 5 7.3 9.7 1.4 9.0 1.4 2.8 1 1 1 3 3 3 0 DltD central region TMEM219 PF14940.1 KRH92812.1 - 0.071 12.2 0.2 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 219 Med4 PF10018.4 KRH92812.1 - 3 7.2 8.9 1.7 7.9 0.3 2.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 KRH92812.1 - 6 6.6 26.4 1.1 9.1 5.7 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCS PF03074.11 KRH92813.1 - 8.6e-30 104.0 7.8 1.7e-29 103.0 5.2 1.5 1 1 0 1 1 1 1 Glutamate-cysteine ligase Linker_histone PF00538.14 KRH92815.1 - 0.069 13.2 0.3 0.082 13.0 0.2 1.2 1 0 0 1 1 1 0 linker histone H1 and H5 family FadA PF09403.5 KRH92815.1 - 0.55 10.2 7.4 0.59 10.1 5.1 1.0 1 0 0 1 1 1 0 Adhesion protein FadA Helicase_C PF00271.26 KRH92816.1 - 2.7e-24 84.8 0.2 9.4e-24 83.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KRH92816.1 - 4.4e-18 65.3 0.6 6.8e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 KRH92816.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain RVP_2 PF08284.6 KRH92817.1 - 5.2e-06 26.4 0.1 7.9e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH92817.1 - 2.8e-05 24.5 0.2 4.6e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH92817.1 - 0.00024 20.9 0.1 0.0005 19.9 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH92817.1 - 0.00035 20.3 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KRH92817.1 - 0.002 17.6 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease SUI1 PF01253.17 KRH92820.1 - 1.8e-14 53.2 4.5 7.8e-13 48.0 3.1 2.2 1 1 0 1 1 1 1 Translation initiation factor SUI1 Drc1-Sld2 PF11719.3 KRH92820.1 - 0.0027 16.8 6.1 0.0033 16.5 4.2 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein MRVI1 PF05781.7 KRH92820.1 - 0.024 13.0 4.9 0.028 12.8 3.4 1.1 1 0 0 1 1 1 0 MRVI1 protein CPSF100_C PF13299.1 KRH92820.1 - 0.025 14.7 1.1 0.034 14.3 0.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TORC_M PF12885.2 KRH92820.1 - 0.028 14.1 0.5 0.033 13.9 0.4 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain CDC45 PF02724.9 KRH92820.1 - 0.13 10.3 1.9 0.14 10.1 1.3 1.0 1 0 0 1 1 1 0 CDC45-like protein FANCI_S2 PF14676.1 KRH92820.1 - 0.26 11.1 1.6 0.42 10.4 1.1 1.3 1 1 0 1 1 1 0 FANCI solenoid 2 EF-1_beta_acid PF10587.4 KRH92820.1 - 0.33 11.1 5.3 0.81 9.8 3.6 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region RRN3 PF05327.6 KRH92820.1 - 0.4 8.7 2.5 0.43 8.6 1.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 U1snRNP70_N PF12220.3 KRH92820.1 - 0.59 10.4 7.8 0.88 9.9 5.4 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rota_VP2 PF05087.7 KRH92820.1 - 9.7 3.9 7.3 12 3.6 5.1 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein ArfGap PF01412.13 KRH92821.1 - 1.7e-12 47.1 2.5 1.7e-12 47.1 1.8 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf zf-C3HC4_3 PF13920.1 KRH92821.1 - 0.22 11.2 2.6 0.38 10.4 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IF4E PF01652.13 KRH92823.1 - 2e-35 121.7 0.5 2.5e-35 121.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sulfate_transp PF00916.15 KRH92825.1 - 3.1e-10 39.5 2.8 8.2e-10 38.1 1.9 1.7 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 KRH92825.1 - 0.00084 18.7 0.2 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 STAS domain GCS2 PF04107.8 KRH92825.1 - 0.089 11.8 0.1 6.8 5.6 0.1 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) dCMP_cyt_deam_1 PF00383.17 KRH92826.1 - 5.3e-18 64.5 1.4 2.8e-17 62.2 0.9 1.9 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region PLAC8 PF04749.12 KRH92826.1 - 0.047 14.2 3.4 0.047 14.2 2.4 1.8 1 1 1 2 2 2 0 PLAC8 family Tub PF01167.13 KRH92827.1 - 1.5e-14 53.6 0.2 1.6e-14 53.4 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3781 PF12636.2 KRH92827.1 - 0.048 13.6 0.2 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) ArfGap PF01412.13 KRH92829.1 - 1.4e-29 102.2 1.0 1.4e-29 102.2 0.7 2.2 1 1 0 2 2 2 1 Putative GTPase activating protein for Arf VitD-bind_III PF09164.5 KRH92829.1 - 0.03 13.9 1.1 0.082 12.5 0.1 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III ABC2_membrane_3 PF12698.2 KRH92829.1 - 0.69 8.8 10.3 0.95 8.4 7.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein rve PF00665.21 KRH92830.1 - 6.5e-10 39.1 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92830.1 - 0.033 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 DDE domain U3_assoc_6 PF08640.6 KRH92831.1 - 0.0039 16.9 0.6 0.0045 16.7 0.4 1.1 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Ribosomal_L19e PF01280.15 KRH92832.1 - 2.4e-45 153.9 5.3 2.9e-45 153.6 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e B-block_TFIIIC PF04182.7 KRH92832.1 - 0.059 13.2 0.2 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Cpn60_TCP1 PF00118.19 KRH92833.1 - 3.6e-114 382.0 7.3 5.3e-114 381.5 5.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DDE_Tnp_IS1595 PF12762.2 KRH92834.1 - 1.4e-17 63.9 0.1 1.8e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.1 KRH92834.1 - 0.0016 18.3 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 DDE domain Beta-TrCP_D PF12125.3 KRH92834.1 - 0.11 12.1 2.4 7.8 6.1 0.3 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP YajC PF02699.10 KRH92834.1 - 0.9 9.2 3.6 2.6 7.7 0.0 2.6 2 1 1 3 3 3 0 Preprotein translocase subunit zf-CCHC PF00098.18 KRH92836.1 - 3.6e-07 29.7 1.8 5.6e-07 29.1 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KRH92836.1 - 0.11 12.1 4.3 0.07 12.8 1.7 1.9 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 KRH92836.1 - 0.15 11.7 1.5 0.3 10.7 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle G-gamma PF00631.17 KRH92836.1 - 0.43 10.3 2.6 0.44 10.3 0.6 1.9 2 0 0 2 2 2 0 GGL domain B2-adapt-app_C PF09066.5 KRH92838.1 - 0.067 13.0 0.2 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Transposase_mut PF00872.13 KRH92839.1 - 1.5e-06 27.0 0.5 1.7e-06 26.8 0.3 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.4 KRH92839.1 - 0.0071 16.4 0.2 0.019 15.0 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain Guanylate_kin PF00625.16 KRH92839.1 - 0.089 12.2 0.4 0.25 10.7 0.1 1.8 1 1 1 2 2 2 0 Guanylate kinase TPT PF03151.11 KRH92841.1 - 5e-15 55.4 27.2 2.9e-08 33.4 16.6 3.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family Aconitase_2_N PF06434.8 KRH92842.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Glyco_transf_92 PF01697.22 KRH92843.1 - 0.12 11.6 0.2 0.12 11.6 0.2 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 92 DUF1283 PF06932.6 KRH92844.1 - 0.018 15.0 0.1 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) FeThRed_A PF02941.10 KRH92844.1 - 0.11 12.3 0.3 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain IF4E PF01652.13 KRH92846.1 - 1.7e-26 92.7 0.5 2e-26 92.5 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E V-ATPase_H_C PF11698.3 KRH92847.1 - 4.4e-17 62.0 0.0 2.1e-16 59.8 0.0 2.2 1 0 0 1 1 1 1 V-ATPase subunit H dUTPase PF00692.14 KRH92849.1 - 2.4e-09 36.7 0.1 3.5e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 dUTPase PMM PF03332.8 KRH92850.1 - 2.6e-78 262.5 0.8 1.8e-66 223.8 0.2 2.2 2 0 0 2 2 2 2 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KRH92850.1 - 0.0008 19.0 0.2 0.0008 19.0 0.1 3.3 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KRH92850.1 - 0.0027 17.0 0.0 0.29 10.3 0.0 2.6 3 0 0 3 3 3 2 Sucrose-6F-phosphate phosphohydrolase DNA_topoisoIV PF00521.15 KRH92851.1 - 4.4e-108 361.8 14.3 2.3e-85 286.9 0.4 2.1 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A HipA_C PF07804.7 KRH92851.1 - 0.035 14.2 0.1 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 HipA-like C-terminal domain Inhibitor_I9 PF05922.11 KRH92851.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I9 DUF2201_N PF13203.1 KRH92851.1 - 7.8 5.5 5.7 11 5.0 4.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Thioredoxin PF00085.15 KRH92853.1 - 5.3e-06 26.0 0.0 6.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KRH92853.1 - 0.0097 14.6 0.3 0.054 12.2 0.2 1.8 1 1 0 1 1 1 1 Phosducin DUF1510 PF07423.6 KRH92854.1 - 0.00039 19.8 1.4 0.00048 19.5 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 KRH92854.1 - 0.001 18.1 0.1 0.0011 18.0 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ETRAMP PF09716.5 KRH92854.1 - 0.0018 18.1 4.8 0.0045 16.9 3.3 1.6 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4448 PF14610.1 KRH92854.1 - 0.014 14.9 0.4 0.016 14.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) HSP90 PF00183.13 KRH92854.1 - 0.016 13.6 5.7 0.018 13.4 4.0 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF3381 PF11861.3 KRH92854.1 - 0.036 13.5 9.7 0.042 13.3 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MecA PF05389.7 KRH92854.1 - 0.042 13.3 4.0 0.048 13.2 2.8 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) TRAP_alpha PF03896.11 KRH92854.1 - 0.046 12.7 1.2 0.048 12.6 0.8 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mem_trans PF03547.13 KRH92854.1 - 0.055 11.7 1.0 0.068 11.4 0.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.6 KRH92854.1 - 0.061 12.9 0.4 0.075 12.6 0.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peroxin-13_N PF04088.8 KRH92854.1 - 0.063 13.2 0.6 0.075 12.9 0.4 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region SID-1_RNA_chan PF13965.1 KRH92854.1 - 0.077 11.1 1.7 0.084 11.0 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.5 KRH92854.1 - 0.091 12.5 1.8 0.11 12.2 1.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM176 PF14851.1 KRH92854.1 - 0.099 12.3 1.0 0.12 12.0 0.7 1.2 1 0 0 1 1 1 0 FAM176 family Dynein_heavy PF03028.10 KRH92854.1 - 0.1 10.6 2.3 0.11 10.4 1.6 1.0 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor DUF3169 PF11368.3 KRH92854.1 - 0.11 11.7 2.9 0.081 12.1 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF3357 PF11837.3 KRH92854.1 - 0.12 12.2 0.3 3.5 7.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) RP-C_C PF11800.3 KRH92854.1 - 0.16 11.6 1.2 0.19 11.4 0.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Vma12 PF11712.3 KRH92854.1 - 0.24 11.0 3.3 0.13 11.9 1.2 1.5 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Bap31 PF05529.7 KRH92854.1 - 0.27 10.6 1.9 0.35 10.3 1.3 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Sec62 PF03839.11 KRH92854.1 - 0.32 10.3 4.0 0.35 10.2 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Spore_III_AF PF09581.5 KRH92854.1 - 0.55 10.0 6.7 0.62 9.9 4.6 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) YqfQ PF14181.1 KRH92854.1 - 0.55 10.2 8.9 0.64 10.0 6.2 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF3464 PF11947.3 KRH92854.1 - 0.69 9.3 4.9 0.96 8.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GAGA_bind PF06217.7 KRH92854.1 - 0.91 9.4 5.6 1.1 9.1 3.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3899 PF13038.1 KRH92854.1 - 1.1 9.4 3.7 0.46 10.6 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) Tim54 PF11711.3 KRH92854.1 - 1.5 7.2 8.2 1.8 7.0 5.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4519 PF15012.1 KRH92854.1 - 3.9 7.4 8.5 0.12 12.3 1.6 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4519) DUF912 PF06024.7 KRH92854.1 - 6.6 6.8 13.4 0.73 9.9 4.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2370 PF10176.4 KRH92854.1 - 7.1 5.8 11.7 28 3.9 8.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) EMP24_GP25L PF01105.19 KRH92858.1 - 0.045 13.4 2.7 0.073 12.7 1.9 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HTH_Tnp_Tc3_2 PF01498.13 KRH92859.1 - 7.5e-14 51.5 2.2 2.6e-13 49.8 0.4 2.1 2 0 0 2 2 2 1 Transposase HTH_24 PF13412.1 KRH92859.1 - 0.00019 20.7 0.9 0.032 13.6 0.1 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 KRH92859.1 - 0.00071 19.0 0.1 0.062 12.8 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 KRH92859.1 - 0.00089 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KRH92859.1 - 0.0038 16.8 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.2 KRH92859.1 - 0.0076 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 KRH92859.1 - 0.0087 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain Bunya_NS-S_2 PF03231.8 KRH92859.1 - 0.02 13.4 0.2 0.032 12.8 0.1 1.4 1 1 0 1 1 1 0 Bunyavirus non-structural protein NS-S 3HCDH PF00725.17 KRH92859.1 - 0.034 14.5 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain TrmB PF01978.14 KRH92859.1 - 0.037 13.7 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF977 PF06163.6 KRH92859.1 - 0.042 13.5 0.2 0.06 13.0 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_28 PF13518.1 KRH92859.1 - 0.077 13.0 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_33 PF13592.1 KRH92859.1 - 0.11 12.0 0.1 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_1 PF11427.3 KRH92859.1 - 0.12 12.0 0.2 14 5.3 0.0 2.6 2 1 0 2 2 2 0 Tc3 transposase HIN PF02760.10 KRH92859.1 - 0.24 10.7 3.0 0.35 10.2 1.7 1.7 1 1 0 1 1 1 0 HIN-200/IF120x domain YgaB PF14182.1 KRH92859.1 - 0.45 10.7 4.9 2.4 8.4 0.1 2.8 2 1 1 3 3 3 0 YgaB-like protein Noc2 PF03715.8 KRH92861.1 - 1e-08 34.3 3.1 1e-08 34.3 2.1 2.1 2 0 0 2 2 2 1 Noc2p family Choline_kinase PF01633.15 KRH92862.1 - 1.6e-13 50.7 4.8 1.6e-13 50.7 3.3 2.6 3 1 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.18 KRH92862.1 - 6.9e-09 35.7 0.0 2.8e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family B PF02216.11 KRH92862.1 - 0.054 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 B domain tRNA-synt_1 PF00133.17 KRH92864.1 - 1.2e-50 172.1 0.0 1.9e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KRH92864.1 - 2e-24 86.1 2.2 4.3e-24 85.0 1.5 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KRH92864.1 - 3.8e-05 22.9 0.5 0.00082 18.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Endotoxin_N PF03945.9 KRH92864.1 - 0.00036 19.9 0.5 0.00075 18.9 0.1 1.7 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain tRNA-synt_1g PF09334.6 KRH92864.1 - 0.0013 17.4 0.1 0.008 14.8 0.0 2.2 1 1 1 2 2 2 1 tRNA synthetases class I (M) ATP_Ca_trans_C PF12424.3 KRH92864.1 - 0.0092 16.3 1.5 0.016 15.5 0.1 2.1 2 0 0 2 2 2 1 Plasma membrane calcium transporter ATPase C terminal FliM PF02154.10 KRH92865.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Acyltransferase PF01553.16 KRH92866.1 - 3.1e-17 62.2 0.1 7.9e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase rve PF00665.21 KRH92867.1 - 8.4e-21 74.3 0.0 7.4e-20 71.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH92867.1 - 7.9e-20 71.1 1.9 9.7e-20 70.8 0.3 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 KRH92867.1 - 0.04 13.4 0.3 0.42 10.1 0.0 3.0 4 0 0 4 4 4 0 Integrase core domain TMF_TATA_bd PF12325.3 KRH92867.1 - 0.04 13.6 0.6 0.13 12.0 0.5 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DNA_pol_B_palm PF14792.1 KRH92867.1 - 0.052 13.6 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 DNA polymerase beta palm DUF4059 PF13268.1 KRH92869.1 - 1.1 9.4 5.5 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) RRM_5 PF13893.1 KRH92870.1 - 0.0043 16.8 1.5 0.0074 16.1 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92870.1 - 0.0075 16.2 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KRH92870.1 - 0.021 14.4 0.3 0.075 12.6 0.1 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1749 PF08538.5 KRH92871.1 - 2.4e-25 89.0 0.0 3e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KRH92871.1 - 3.1e-07 30.5 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KRH92871.1 - 0.00019 21.1 0.0 0.00097 18.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KRH92871.1 - 0.002 17.1 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 KRH92871.1 - 0.002 17.7 0.0 0.013 15.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 KRH92871.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CTV_P13 PF06922.6 KRH92872.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein ANTAR PF03861.9 KRH92872.1 - 0.12 11.9 0.8 0.75 9.4 0.1 2.2 2 0 0 2 2 2 0 ANTAR domain DX PF01666.12 KRH92873.1 - 0.022 15.1 0.3 0.024 15.0 0.2 1.1 1 0 0 1 1 1 0 DX module Baculo_19 PF04798.7 KRH92873.1 - 0.081 12.3 0.3 0.085 12.2 0.2 1.1 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Borrelia_lipo_2 PF06238.6 KRH92873.1 - 0.15 12.1 2.0 0.16 12.0 1.4 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein RVT_1 PF00078.22 KRH92874.1 - 3.5e-19 69.0 0.0 6.9e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ferritin PF00210.19 KRH92874.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain DDE_1 PF03184.14 KRH92875.1 - 5.1e-18 65.0 0.1 5.9e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Fip1 PF05182.8 KRH92875.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Fip1 motif Saccharop_dh PF03435.13 KRH92876.1 - 1.2e-21 77.1 0.0 8.2e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KRH92876.1 - 0.03 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KRH92876.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding rve PF00665.21 KRH92877.1 - 0.0017 18.4 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DUF1758 PF05585.7 KRH92877.1 - 0.046 13.2 0.1 0.051 13.1 0.1 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Preseq_ALAS PF09029.5 KRH92878.1 - 0.054 13.5 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence DUF3221 PF11518.3 KRH92878.1 - 0.074 12.7 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) rve PF00665.21 KRH92879.1 - 3.2e-16 59.5 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain PGM_PMM_I PF02878.11 KRH92882.1 - 6.6e-17 61.2 0.0 1.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 KRH92882.1 - 3.2e-05 23.8 0.1 0.00013 21.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KRH92882.1 - 0.00024 21.3 0.0 0.018 15.3 0.0 3.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Yae1_N PF09811.4 KRH92882.1 - 0.00054 19.4 7.1 0.00098 18.6 4.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SET PF00856.23 KRH92883.1 - 2.6e-23 83.0 0.3 2.6e-23 83.0 0.2 3.6 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 KRH92884.1 - 0.097 12.0 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 Histone lysine methyltransferase SET associated DAO PF01266.19 KRH92885.1 - 2.4e-45 154.9 0.0 3.7e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KRH92885.1 - 1.7e-06 27.1 2.2 0.0034 16.2 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KRH92885.1 - 0.00045 19.4 0.4 0.00085 18.5 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KRH92885.1 - 0.00067 19.5 1.1 0.0031 17.4 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KRH92885.1 - 0.0034 16.3 1.6 0.032 13.0 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DUF4130 PF13566.1 KRH92885.1 - 0.037 13.5 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 Lycopene_cycl PF05834.7 KRH92885.1 - 0.13 11.1 0.2 2.8 6.7 0.5 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KRH92885.1 - 0.23 11.5 1.6 1.8 8.6 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ribosomal_L40e PF01020.12 KRH92886.1 - 9.5e-16 57.1 10.8 1.4e-15 56.6 7.5 1.2 1 0 0 1 1 1 1 Ribosomal L40e family zf-DHHC PF01529.15 KRH92886.1 - 0.075 12.4 3.1 0.096 12.0 2.0 1.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase HypA PF01155.14 KRH92886.1 - 0.09 12.4 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family tRNA-synt_2 PF00152.15 KRH92887.1 - 2.6e-26 92.2 0.2 3.7e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KRH92887.1 - 1.9e-10 40.4 0.1 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_1 PF00133.17 KRH92888.1 - 8.1e-14 50.5 0.1 1.4e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KRH92888.1 - 5.3e-10 38.5 0.2 1.2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (M) Sushi_2 PF09014.5 KRH92888.1 - 0.28 10.9 2.2 0.51 10.1 0.2 2.2 1 1 1 2 2 2 0 Beta-2-glycoprotein-1 fifth domain GCD14 PF08704.5 KRH92889.1 - 6.1e-23 81.5 0.2 1.5e-21 77.0 0.0 2.5 2 1 1 3 3 3 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 KRH92889.1 - 0.00016 20.7 0.1 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KRH92889.1 - 0.025 14.1 0.6 0.067 12.7 0.4 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KRH92889.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KRH92889.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KRH92889.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD_2 PF06733.10 KRH92890.1 - 1.4e-33 115.7 13.2 2.7e-31 108.3 9.2 2.8 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KRH92890.1 - 4.9e-06 26.1 0.2 0.00085 18.8 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KRH92890.1 - 0.074 12.8 0.0 0.074 12.8 0.0 4.5 4 2 1 5 5 5 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KRH92890.1 - 0.49 10.5 3.5 13 5.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain Lipase_GDSL_3 PF14606.1 KRH92890.1 - 0.61 9.7 4.1 9.3 5.9 0.8 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Sec1 PF00995.18 KRH92891.1 - 1.2e-40 139.7 25.9 1.8e-40 139.1 17.9 1.2 1 0 0 1 1 1 1 Sec1 family Ricin_B_lectin PF00652.17 KRH92893.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain CBM49 PF09478.5 KRH92893.1 - 0.049 13.7 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain CBM49 DUF106 PF01956.11 KRH92894.1 - 0.04 13.4 0.8 0.098 12.1 0.6 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF106 zf-CCHC PF00098.18 KRH92897.1 - 1.1e-06 28.3 2.0 2e-06 27.4 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KRH92897.1 - 0.063 12.9 2.7 0.14 11.8 1.9 1.8 1 1 0 1 1 1 0 Zinc knuckle zf-HC5HC2H PF13771.1 KRH92897.1 - 0.069 13.2 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1492 PF07374.6 KRH92897.1 - 0.071 13.2 0.5 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Ax_dynein_light PF10211.4 KRH92897.1 - 0.15 11.8 3.3 0.18 11.6 2.3 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain zf-CCHC_6 PF15288.1 KRH92897.1 - 2.6 7.8 6.0 0.92 9.2 1.5 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 KRH92898.1 - 9e-06 25.1 0.0 9.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.9 KRH92898.1 - 0.077 12.5 0.1 0.092 12.3 0.1 1.1 1 0 0 1 1 1 0 PRELI-like family DUF2119 PF09892.4 KRH92898.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) RVT_1 PF00078.22 KRH92899.1 - 5.6e-07 29.1 0.2 5.8e-07 29.0 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) B5 PF03484.10 KRH92900.1 - 7.5e-08 32.1 0.1 7.5e-08 32.1 0.1 3.6 4 0 0 4 4 4 1 tRNA synthetase B5 domain Pkinase PF00069.20 KRH92901.1 - 1e-66 224.7 1.4 1.8e-66 223.9 1.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92901.1 - 2.3e-39 135.0 0.2 3.3e-39 134.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH92901.1 - 5.1e-10 38.7 0.0 7.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KRH92901.1 - 0.0028 16.7 0.1 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.17 KRH92902.1 - 0.00046 20.0 0.1 0.23 11.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KRH92902.1 - 0.002 18.3 0.0 0.24 11.7 0.0 3.4 2 1 2 4 4 4 2 HEAT repeats ECM11 PF15463.1 KRH92902.1 - 0.039 14.2 0.6 0.087 13.1 0.4 1.5 1 0 0 1 1 1 0 Extracellular mutant protein 11 DDE_Tnp_IS1595 PF12762.2 KRH92904.1 - 0.023 14.5 0.2 0.031 14.1 0.1 1.4 1 1 1 2 2 2 0 ISXO2-like transposase domain Cas_Cas6 PF01881.11 KRH92904.1 - 0.024 14.8 2.6 0.025 14.8 1.8 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas6 SporV_AA PF12164.3 KRH92904.1 - 0.076 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AA DNA_pol_alpha_N PF12254.3 KRH92904.1 - 0.1 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal UN_NPL4 PF11543.3 KRH92905.1 - 0.011 16.0 0.1 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 DUF4542 PF15075.1 KRH92905.1 - 1.1 9.2 4.4 3.1 7.7 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4542) DUF1561 PF07598.6 KRH92906.1 - 0.048 11.6 0.3 0.051 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) HSP70 PF00012.15 KRH92907.1 - 3.8e-96 322.3 26.7 2.7e-48 164.3 13.2 2.7 1 1 2 3 3 3 2 Hsp70 protein FtsA PF14450.1 KRH92907.1 - 0.36 10.6 8.1 1.5 8.6 0.2 3.6 4 0 0 4 4 4 0 Cell division protein FtsA Vfa1 PF08432.5 KRH92907.1 - 1.3 8.9 19.7 2.4 8.1 4.2 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 KRH92907.1 - 2.1 7.9 8.0 1 8.9 3.8 1.8 2 0 0 2 2 2 0 IncA protein DDE_Tnp_IS1595 PF12762.2 KRH92909.1 - 5.1e-29 101.0 0.0 6.8e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 KRH92909.1 - 6.3e-08 32.1 0.0 8.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family rve PF00665.21 KRH92909.1 - 0.0026 17.8 0.1 0.006 16.6 0.1 1.6 1 1 0 1 1 1 1 Integrase core domain HIG_1_N PF04588.8 KRH92911.1 - 0.052 13.2 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Hypoxia induced protein conserved region DUF1228 PF06779.9 KRH92911.1 - 0.06 13.3 0.7 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) HlyIII PF03006.15 KRH92911.1 - 1.6 8.0 11.1 3.1 7.1 0.7 2.2 2 0 0 2 2 2 0 Haemolysin-III related OppC_N PF12911.2 KRH92912.1 - 1.3 8.4 0.0 1.3 8.4 0.0 3.8 3 1 1 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C EFP_N PF08207.7 KRH92913.1 - 3.3e-05 23.6 0.6 5.7e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain AAA PF00004.24 KRH92915.1 - 7.8e-16 58.4 2.1 1.1e-15 57.9 0.3 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KRH92915.1 - 4.6e-15 55.6 4.2 1.3e-13 50.8 0.2 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 KRH92915.1 - 1.4e-10 40.5 0.1 3.5e-10 39.3 0.1 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KRH92915.1 - 1.6e-09 37.0 4.7 1.5e-08 33.8 0.1 2.1 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KRH92915.1 - 1.8e-07 31.0 1.4 2.8e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 Replication factor C C-terminal domain AAA_14 PF13173.1 KRH92915.1 - 2.2e-07 30.8 2.9 6.8e-07 29.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KRH92915.1 - 3.5e-07 30.4 1.1 9.3e-06 25.8 0.1 2.9 1 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 KRH92915.1 - 4.1e-07 30.8 0.1 9.8e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH92915.1 - 1.5e-06 27.8 0.0 3.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KRH92915.1 - 1.7e-06 28.3 3.0 2.8e-05 24.4 2.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH92915.1 - 4.7e-06 26.7 0.0 3.2e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KRH92915.1 - 5.1e-06 26.2 0.7 0.00014 21.5 0.0 3.3 2 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KRH92915.1 - 6.8e-06 25.7 0.1 2.2e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 KRH92915.1 - 3.9e-05 23.2 0.7 6.8e-05 22.4 0.5 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 KRH92915.1 - 4.8e-05 23.4 0.1 0.00017 21.6 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KRH92915.1 - 7.2e-05 22.0 0.0 0.00081 18.5 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KRH92915.1 - 8.9e-05 22.1 0.3 0.00026 20.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KRH92915.1 - 0.00012 21.5 0.3 0.00038 19.9 0.0 1.9 2 1 0 2 2 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KRH92915.1 - 0.00014 21.3 0.1 0.01 15.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain DEAD PF00270.24 KRH92915.1 - 0.00018 21.0 0.5 0.088 12.2 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KRH92915.1 - 0.0002 21.0 2.2 0.00038 20.0 1.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KRH92915.1 - 0.00023 20.7 0.7 0.0054 16.2 0.5 3.0 1 1 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 KRH92915.1 - 0.00026 20.7 2.1 0.0082 15.8 0.1 2.4 1 1 1 2 2 2 1 NTPase RNA_helicase PF00910.17 KRH92915.1 - 0.00039 20.5 0.1 0.0023 18.0 0.0 2.2 1 1 1 2 2 2 1 RNA helicase TIP49 PF06068.8 KRH92915.1 - 0.00041 19.1 2.9 0.0072 15.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus MobB PF03205.9 KRH92915.1 - 0.00044 19.9 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 KRH92915.1 - 0.00047 19.4 0.1 0.0011 18.2 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 T2SE PF00437.15 KRH92915.1 - 0.001 18.0 1.1 0.0011 17.9 0.1 1.6 2 0 0 2 2 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 KRH92915.1 - 0.0011 18.7 2.4 0.0013 18.4 0.6 1.9 1 1 1 2 2 2 1 Archaeal ATPase PhoH PF02562.11 KRH92915.1 - 0.0017 17.6 1.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 KRH92915.1 - 0.002 17.5 0.2 0.059 12.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KRH92915.1 - 0.0027 16.6 0.3 0.0096 14.8 0.0 1.8 1 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KRH92915.1 - 0.0028 17.5 0.1 0.0067 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KRH92915.1 - 0.0028 17.3 0.0 0.0095 15.5 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase ResIII PF04851.10 KRH92915.1 - 0.0031 17.3 0.2 0.045 13.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 KRH92915.1 - 0.0043 16.1 0.1 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 KRH92915.1 - 0.0048 16.4 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KRH92915.1 - 0.0057 16.3 0.2 0.48 10.0 0.0 2.9 3 1 1 4 4 3 1 NACHT domain Torsin PF06309.6 KRH92915.1 - 0.0057 16.5 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 Torsin AAA_24 PF13479.1 KRH92915.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KRH92915.1 - 0.0081 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KRH92915.1 - 0.0099 15.8 0.3 0.071 13.0 0.0 2.3 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF258 PF03193.11 KRH92915.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 KRH92915.1 - 0.013 14.4 0.2 0.059 12.3 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KRH92915.1 - 0.014 15.7 2.1 0.029 14.6 1.3 1.9 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 KRH92915.1 - 0.017 14.4 0.5 0.071 12.4 0.1 2.1 1 1 0 2 2 2 0 Thymidylate kinase SRP54 PF00448.17 KRH92915.1 - 0.029 13.8 0.1 0.068 12.6 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.10 KRH92915.1 - 0.03 13.3 0.2 0.071 12.1 0.0 1.6 1 1 0 1 1 1 0 Anion-transporting ATPase PRK PF00485.13 KRH92915.1 - 0.04 13.4 0.0 0.23 10.9 0.0 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 KRH92915.1 - 0.058 12.8 0.2 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.17 KRH92915.1 - 0.071 12.9 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_31 PF13614.1 KRH92915.1 - 0.083 12.8 0.4 0.5 10.2 0.0 2.5 3 2 1 4 4 2 0 AAA domain ArgK PF03308.11 KRH92915.1 - 0.12 11.1 0.2 1.3 7.7 0.1 2.4 2 1 1 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 KRH92915.1 - 0.15 11.6 1.9 7.2 6.0 0.3 2.5 2 2 0 2 2 2 0 Conserved hypothetical ATP binding protein Zot PF05707.7 KRH92915.1 - 0.18 11.2 1.4 3.8 6.9 1.0 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) MS_channel PF00924.13 KRH92918.1 - 3.4e-15 55.9 5.2 3.4e-15 55.9 3.6 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel TFIIA PF03153.8 KRH92920.1 - 5.4e-15 56.1 5.6 3.7e-14 53.4 0.2 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2407_C PF13373.1 KRH92920.1 - 1 9.3 3.1 1.2 9.0 2.1 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF4110 PF13422.1 KRH92920.1 - 1 9.2 3.9 0.9 9.4 1.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4110) ATP-synt_C PF00137.16 KRH92921.1 - 6e-09 35.6 11.6 0.00043 20.1 4.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Sigma_reg_N PF13800.1 KRH92921.1 - 3.6 7.6 6.6 0.44 10.6 0.8 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Sulfate_transp PF00916.15 KRH92922.1 - 7.2e-09 35.0 18.2 1e-08 34.5 9.9 2.8 2 1 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 KRH92922.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MAPEG PF01124.13 KRH92922.1 - 0.023 14.2 0.3 0.023 14.2 0.2 2.3 2 0 0 2 2 2 0 MAPEG family GATA PF00320.22 KRH92923.1 - 3.5e-26 90.2 20.3 1.1e-15 56.6 5.0 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KRH92923.1 - 0.011 14.9 7.1 0.096 12.0 0.6 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.2 KRH92923.1 - 0.077 12.8 9.6 11 5.9 6.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon DUF2387 PF09526.5 KRH92923.1 - 8.8 6.3 12.9 0.66 9.9 0.1 3.9 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) Hexapep PF00132.19 KRH92924.1 - 0.0057 16.1 1.2 0.02 14.4 0.8 1.9 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) RVT_1 PF00078.22 KRH92925.1 - 3.9e-24 85.2 0.3 7e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH92925.1 - 1.6e-09 37.5 0.0 5.6e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 KRH92925.1 - 0.027 13.7 0.1 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase gag-asp_proteas PF13975.1 KRH92925.1 - 0.039 13.7 0.1 0.27 11.0 0.1 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 KRH92925.1 - 0.12 12.4 1.7 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Ribonuc_2-5A PF06479.7 KRH92926.1 - 1.6e-30 105.6 1.9 2.1e-30 105.2 0.4 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.20 KRH92926.1 - 3.2e-15 56.0 12.2 5.4e-13 48.6 2.7 2.6 3 0 0 3 3 3 2 Protein kinase domain MutL_C PF08676.6 KRH92929.1 - 8.1e-06 25.4 0.8 0.023 14.3 0.0 3.1 3 0 0 3 3 3 2 MutL C terminal dimerisation domain Fe_dep_repr_C PF02742.10 KRH92929.1 - 0.076 12.7 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Lactamase_B PF00753.22 KRH92930.1 - 6.8e-14 51.9 0.0 1.4e-13 50.9 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KRH92930.1 - 0.0079 15.7 1.8 0.014 14.8 1.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-CCCH PF00642.19 KRH92931.1 - 1.4e-07 31.0 45.0 0.0026 17.3 0.3 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Chromo PF00385.19 KRH92932.1 - 3.8e-16 58.5 1.0 8.6e-16 57.3 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KRH92932.1 - 0.02 14.7 4.4 0.25 11.1 0.1 2.7 3 0 0 3 3 3 0 Chromo shadow domain Tudor-knot PF11717.3 KRH92932.1 - 0.071 12.8 1.9 0.094 12.4 0.3 2.0 2 1 0 2 2 2 0 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.1 KRH92932.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 CagY_I PF14585.1 KRH92932.1 - 4.6 7.2 6.3 24 4.9 0.1 2.4 1 1 1 2 2 2 0 CagY type 1 repeat WD40 PF00400.27 KRH92935.1 - 3.6e-23 80.5 5.7 1.2e-06 28.1 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KRH92935.1 - 0.017 13.2 0.6 0.079 11.0 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KRH92935.1 - 0.042 14.1 1.5 1.9 8.8 0.0 3.6 3 1 1 4 4 4 0 PQQ-like domain TPR_11 PF13414.1 KRH92935.1 - 0.071 12.7 2.0 0.3 10.7 0.2 2.3 1 1 1 2 2 2 0 TPR repeat TPR_1 PF00515.23 KRH92935.1 - 0.092 12.3 6.5 0.16 11.6 0.3 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KRH92935.1 - 0.12 12.3 1.6 1.7 8.6 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KRH92935.1 - 0.28 11.1 6.9 0.19 11.7 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat BBS2_Mid PF14783.1 KRH92935.1 - 0.86 9.4 8.1 20 4.9 0.0 4.8 4 1 1 6 6 6 0 Ciliary BBSome complex subunit 2, middle region SWIM PF04434.12 KRH92936.1 - 3.6e-06 26.3 0.1 7.6e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Mem_trans PF03547.13 KRH92936.1 - 1.2 7.3 9.1 0.9 7.7 0.7 2.3 2 0 0 2 2 2 0 Membrane transport protein GDA1_CD39 PF01150.12 KRH92937.1 - 3.7e-12 45.4 6.6 1.7e-07 30.1 0.3 3.4 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Nucleoporin_FG PF13634.1 KRH92938.1 - 3.5e-09 36.9 235.9 4.7e-07 30.0 28.3 7.1 2 2 5 7 7 7 5 Nucleoporin FG repeat region ERAP1_C PF11838.3 KRH92939.1 - 1.1e-18 67.5 0.4 2e-18 66.7 0.3 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain rve PF00665.21 KRH92940.1 - 3.1e-17 62.7 0.1 1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH92940.1 - 0.022 14.2 0.2 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain zf-HC2 PF13490.1 KRH92940.1 - 0.036 13.9 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative zinc-finger Ectoine_synth PF06339.7 KRH92941.1 - 0.1 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Ectoine synthase MULE PF10551.4 KRH92942.1 - 0.053 13.6 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 MULE transposase domain DEAD PF00270.24 KRH92943.1 - 7.1e-15 54.9 0.6 1.5e-08 34.3 0.1 3.1 2 1 1 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KRH92943.1 - 3.2e-13 49.8 4.2 3.2e-13 49.8 2.9 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KRH92943.1 - 0.009 15.2 0.1 0.42 9.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 KRH92943.1 - 0.025 13.4 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 KRH92943.1 - 0.12 12.4 4.2 0.56 10.3 0.6 3.1 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KRH92945.1 - 3.7e-16 58.7 18.1 3.4e-13 49.0 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF747 PF05346.6 KRH92945.1 - 0.00036 19.6 0.8 0.00062 18.9 0.4 1.5 1 1 0 1 1 1 1 Eukaryotic membrane protein family RVT_1 PF00078.22 KRH92946.1 - 2.6e-24 85.7 0.1 5.8e-24 84.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH92946.1 - 7.8e-07 28.9 0.1 4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC PF00098.18 KRH92946.1 - 2.5e-05 23.9 2.8 5e-05 23.0 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 KRH92946.1 - 4.7e-05 23.8 0.0 0.00014 22.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH92946.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease eIF3g PF12353.3 KRH92946.1 - 0.031 14.1 4.5 0.042 13.7 2.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Asp_protease PF09668.5 KRH92946.1 - 0.074 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease CmcI PF04989.7 KRH92947.1 - 0.0034 16.7 0.1 0.0048 16.2 0.1 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase DNA_primase_lrg PF04104.9 KRH92948.1 - 1.6e-32 112.8 6.4 2.1e-32 112.3 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RVT_1 PF00078.22 KRH92950.1 - 8.8e-25 87.3 0.1 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 KRH92951.1 - 0.004 17.2 0.5 0.0062 16.5 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PTR PF12789.2 KRH92951.1 - 0.022 14.5 0.6 0.054 13.3 0.4 1.7 1 0 0 1 1 1 0 Phage tail repeat like CARD PF00619.16 KRH92951.1 - 0.051 13.4 1.9 2.6 7.9 0.4 2.3 2 0 0 2 2 2 0 Caspase recruitment domain DUF221 PF02714.10 KRH92952.1 - 0.029 13.2 0.5 0.029 13.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 ATP-synt_8 PF00895.15 KRH92952.1 - 0.078 13.1 1.8 0.088 13.0 1.3 1.1 1 0 0 1 1 1 0 ATP synthase protein 8 ABC2_membrane_3 PF12698.2 KRH92952.1 - 0.15 11.0 0.9 0.15 11.0 0.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein tRNA-synt_2b PF00587.20 KRH92955.1 - 1.2e-29 103.1 0.1 2.2e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KRH92955.1 - 6.9e-08 32.4 17.5 1.9e-06 27.8 12.1 2.4 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.9 KRH92955.1 - 0.025 14.5 5.0 0.043 13.7 3.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GLE1 PF07817.8 KRH92955.1 - 0.037 12.9 4.6 0.07 12.0 3.2 1.4 1 0 0 1 1 1 0 GLE1-like protein DUF3450 PF11932.3 KRH92955.1 - 0.91 8.7 6.5 2.1 7.5 3.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlxA PF14282.1 KRH92955.1 - 1 9.3 8.1 2.3 8.2 5.6 1.5 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 KRH92955.1 - 1.1 9.1 15.5 2.3 8.1 7.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2681 PF10883.3 KRH92955.1 - 1.2 9.3 14.2 4.6 7.5 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Pkinase PF00069.20 KRH92956.1 - 2e-34 118.9 12.9 2.2e-18 66.3 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KRH92956.1 - 4.9e-17 61.8 0.1 1.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1041 PF06292.12 KRH92957.1 - 0.067 13.3 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) AAA_22 PF13401.1 KRH92958.1 - 5e-08 33.1 0.0 7.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KRH92958.1 - 8.5e-06 24.8 0.2 1.2e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KRH92958.1 - 5e-05 23.3 0.0 0.00015 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KRH92958.1 - 0.00048 20.0 1.5 0.017 15.0 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH92958.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KRH92958.1 - 0.00083 19.1 0.7 0.0012 18.5 0.5 1.2 1 0 0 1 1 1 1 Archaeal ATPase Viral_helicase1 PF01443.13 KRH92958.1 - 0.001 18.6 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 KRH92958.1 - 0.0041 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KRH92958.1 - 0.0048 17.2 0.8 0.011 16.0 0.6 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KRH92958.1 - 0.0065 15.6 0.4 0.013 14.6 0.3 1.4 1 1 0 1 1 1 1 KaiC NACHT PF05729.7 KRH92958.1 - 0.007 16.0 0.6 0.11 12.2 0.4 2.1 1 1 0 1 1 1 1 NACHT domain GvpD PF07088.6 KRH92958.1 - 0.016 13.5 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein DUF2075 PF09848.4 KRH92958.1 - 0.02 13.8 0.2 0.046 12.7 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KRH92958.1 - 0.023 14.1 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Kinesin PF00225.18 KRH92958.1 - 0.028 13.1 0.1 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain RNA_helicase PF00910.17 KRH92958.1 - 0.028 14.5 0.2 0.24 11.6 0.0 2.1 1 1 1 2 2 2 0 RNA helicase AAA_11 PF13086.1 KRH92958.1 - 0.045 13.3 1.9 0.14 11.7 0.5 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KRH92958.1 - 0.068 13.2 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 KRH92958.1 - 0.07 12.1 0.0 6.6 5.6 0.0 2.5 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 KRH92958.1 - 0.091 12.2 0.2 0.56 9.6 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 KRH92958.1 - 0.1 12.2 0.7 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.1 KRH92958.1 - 0.12 13.1 1.9 0.2 12.5 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KRH92958.1 - 0.22 11.7 1.1 1.2 9.3 0.8 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KRH92958.1 - 0.23 11.2 2.5 0.92 9.3 1.7 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit YcxB PF14317.1 KRH92958.1 - 0.4 9.9 2.7 6.4 6.1 0.1 2.7 3 0 0 3 3 2 0 YcxB-like protein TetR_C_8 PF14278.1 KRH92959.1 - 0.06 13.7 1.9 10 6.6 0.1 2.5 1 1 2 3 3 3 0 Transcriptional regulator C-terminal region ApoB100_C PF12491.3 KRH92959.1 - 0.11 12.1 3.1 5.4 6.7 0.1 2.3 1 1 1 2 2 2 0 Apolipoprotein B100 C terminal PCNA_N PF00705.13 KRH92960.1 - 2.7e-20 72.1 2.0 2.7e-20 72.1 0.4 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KRH92960.1 - 1e-19 70.7 1.8 1e-16 61.0 0.2 2.3 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KRH92960.1 - 8.3e-05 21.8 1.7 0.00013 21.1 1.2 1.4 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.7 KRH92960.1 - 0.032 13.1 0.2 0.59 9.0 0.1 2.1 1 1 0 2 2 2 0 Hus1-like protein Med16 PF11635.3 KRH92960.1 - 0.094 10.6 1.2 0.44 8.4 0.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 16 RRM_1 PF00076.17 KRH92961.1 - 1.2e-46 156.1 6.2 2.5e-16 59.0 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92961.1 - 5e-37 125.7 0.2 7.5e-12 45.0 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH92961.1 - 2.7e-23 81.5 4.9 6.4e-08 32.3 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KRH92961.1 - 4e-08 32.8 0.0 0.012 15.3 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KRH92961.1 - 2.3e-05 24.0 3.7 0.071 12.8 0.1 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KRH92961.1 - 0.00092 18.9 0.2 3.3 7.5 0.0 3.4 3 1 0 3 3 3 2 Limkain b1 RNA_bind PF08675.6 KRH92961.1 - 0.054 13.4 1.6 14 5.7 0.0 4.1 3 1 1 4 4 4 0 RNA binding domain PABP PF00658.13 KRH92961.1 - 0.12 12.0 0.0 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 Poly-adenylate binding protein, unique domain Helicase_C_2 PF13307.1 KRH92962.1 - 5.3e-37 127.3 1.3 1.4e-35 122.7 0.9 2.3 1 1 0 1 1 1 1 Helicase C-terminal domain CAP PF00188.21 KRH92964.1 - 0.00078 19.9 0.5 0.0021 18.5 0.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Syja_N PF02383.13 KRH92965.1 - 4.9e-21 74.8 17.8 1.2e-17 63.6 0.4 3.0 2 1 1 3 3 3 2 SacI homology domain rve PF00665.21 KRH92967.1 - 2.2e-21 76.2 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH92967.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH92967.1 - 0.0023 17.9 0.4 0.004 17.1 0.3 1.4 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.1 KRH92967.1 - 0.032 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_IS1 PF03400.8 KRH92967.1 - 0.11 12.6 0.6 0.34 11.0 0.4 1.7 1 1 0 1 1 1 0 IS1 transposase Ribonuc_red_sm PF00268.16 KRH92970.1 - 2.9e-107 357.8 10.8 4e-107 357.4 7.5 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF3914 PF13053.1 KRH92970.1 - 0.069 13.3 1.9 0.18 12.0 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) RVT_1 PF00078.22 KRH92971.1 - 1.3e-06 27.8 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH92972.1 - 8.6e-22 77.5 0.2 2.9e-21 75.8 0.2 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 KRH92972.1 - 6.3e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 KRH92972.1 - 0.00017 21.3 2.1 0.00039 20.2 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Peptidase_A2B PF12384.3 KRH92972.1 - 0.0014 17.9 0.1 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ty3 transposon peptidase AF0941-like PF14591.1 KRH92972.1 - 0.0054 16.7 0.5 0.02 14.9 0.4 2.1 1 0 0 1 1 1 1 AF0941-like RVP PF00077.15 KRH92972.1 - 0.017 15.0 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.1 KRH92972.1 - 0.022 14.2 0.2 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Scytalone_dh PF02982.9 KRH92972.1 - 0.063 12.8 0.1 0.71 9.4 0.0 2.5 2 0 0 2 2 2 0 Scytalone dehydratase zf-CCHC_6 PF15288.1 KRH92972.1 - 0.097 12.3 0.6 0.19 11.3 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 KRH92972.1 - 0.1 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UCH PF00443.24 KRH92973.1 - 0.0064 15.6 5.7 0.055 12.5 1.1 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S3Ae PF01015.13 KRH92974.1 - 1.7e-41 141.7 11.8 2.1e-41 141.4 8.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ribosomal_L18p PF00861.17 KRH92974.1 - 0.062 13.4 1.0 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 Ribosomal L18p/L5e family MSG PF02349.10 KRH92974.1 - 2.4 8.2 6.2 0.53 10.3 1.0 2.3 2 0 0 2 2 2 0 Major surface glycoprotein DivIC PF04977.10 KRH92975.1 - 0.23 10.9 0.2 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator PLDc_N PF13396.1 KRH92976.1 - 0.012 15.2 0.2 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal GPI-anchored PF10342.4 KRH92976.1 - 0.019 15.4 0.8 0.055 13.9 0.5 1.9 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SusE PF14292.1 KRH92976.1 - 0.092 12.5 0.1 0.092 12.5 0.0 1.5 2 0 0 2 2 2 0 SusE outer membrane protein DUF2621 PF11084.3 KRH92977.1 - 0.021 14.4 0.1 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) RskA PF10099.4 KRH92977.1 - 0.048 13.4 0.0 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ferric_reduct PF01794.14 KRH92977.1 - 0.068 13.2 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase like transmembrane component SHR3_chaperone PF08229.6 KRH92977.1 - 0.096 11.6 0.8 0.67 8.8 0.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 ABC2_membrane_3 PF12698.2 KRH92977.1 - 0.25 10.3 2.0 0.51 9.3 1.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein tRNA-synt_2b PF00587.20 KRH92979.1 - 1.3e-21 76.9 0.5 3.3e-21 75.6 0.2 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KRH92979.1 - 1.8e-13 50.2 3.3 5.8e-13 48.6 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain DHOase PF12890.2 KRH92979.1 - 0.008 15.8 1.0 0.18 11.4 0.1 2.2 2 0 0 2 2 2 1 Dihydro-orotase-like Plant_all_beta PF10532.4 KRH92980.1 - 0.00098 19.1 0.8 0.0015 18.6 0.6 1.2 1 0 0 1 1 1 1 Plant specific N-all beta domain Ribosomal_L5_C PF00673.16 KRH92981.1 - 7.6e-22 76.8 0.5 1.2e-21 76.2 0.3 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KRH92981.1 - 1.1e-14 53.8 0.5 6.6e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 MCM PF00493.18 KRH92983.1 - 5.7e-115 383.6 0.9 9.5e-115 382.9 0.6 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KRH92983.1 - 3.4e-09 36.1 0.1 1.2e-06 27.8 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 KRH92983.1 - 8.1e-07 29.5 1.0 2.4e-06 28.0 0.7 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 KRH92983.1 - 4.9e-06 26.3 0.2 2.3e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KRH92983.1 - 0.00013 21.4 0.4 0.0037 16.7 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_3 PF07726.6 KRH92983.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hist_deacetyl PF00850.14 KRH92985.1 - 4.5e-24 85.2 0.0 8.4e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain DUF1103 PF06513.6 KRH92985.1 - 0.0032 16.8 9.7 0.0047 16.3 6.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF445 PF04286.7 KRH92985.1 - 0.038 13.5 1.3 0.054 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NIL PF09383.5 KRH92985.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NIL domain SseC PF04888.7 KRH92985.1 - 0.14 11.4 1.3 0.25 10.6 0.9 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Pro_dh-DNA_bdg PF14850.1 KRH92985.1 - 0.24 11.6 2.0 1.1 9.4 1.5 1.9 1 1 1 2 2 2 0 DNA-binding domain of Proline dehydrogenase PNPase PF03726.9 KRH92985.1 - 1.2 9.4 4.8 5.9 7.2 2.9 2.3 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain SRI PF08236.6 KRH92985.1 - 9.5 6.2 13.6 3.8 7.5 1.4 4.1 3 1 2 5 5 5 0 SRI (Set2 Rpb1 interacting) domain Phe_tRNA-synt_N PF02912.13 KRH92986.1 - 0.01 15.5 0.3 0.03 14.0 0.2 1.7 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain MBD_C PF14048.1 KRH92988.1 - 0.0032 18.0 1.3 0.0094 16.5 0.1 2.2 2 1 1 3 3 3 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF3040 PF11239.3 KRH92988.1 - 0.17 11.9 0.5 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RGS PF00615.14 KRH92988.1 - 0.24 11.5 14.8 0.67 10.0 1.5 3.0 1 1 2 3 3 3 0 Regulator of G protein signaling domain DUF3347 PF11827.3 KRH92988.1 - 0.53 10.2 12.8 2.4 8.1 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) MCPsignal PF00015.16 KRH92988.1 - 6.2 6.3 17.2 0.47 9.9 5.7 2.6 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SNARE PF05739.14 KRH92988.1 - 7.6 6.3 12.8 0.082 12.6 0.7 3.5 3 1 1 4 4 4 0 SNARE domain Peptidase_C48 PF02902.14 KRH92989.1 - 2.7e-25 89.2 1.0 4.9e-25 88.4 0.7 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TetR_C_8 PF14278.1 KRH92989.1 - 0.3 11.4 5.0 4.2 7.8 1.2 2.5 1 1 1 2 2 2 0 Transcriptional regulator C-terminal region Sec20 PF03908.8 KRH92990.1 - 2.9e-05 23.6 0.5 3.5e-05 23.4 0.3 1.1 1 0 0 1 1 1 1 Sec20 SNARE PF05739.14 KRH92990.1 - 0.0043 16.7 1.0 0.0059 16.2 0.7 1.2 1 0 0 1 1 1 1 SNARE domain V-SNARE_C PF12352.3 KRH92990.1 - 0.0091 16.0 0.4 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 KRH92990.1 - 0.012 13.7 0.4 0.013 13.6 0.3 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 ETRAMP PF09716.5 KRH92990.1 - 0.035 14.0 0.6 0.043 13.7 0.4 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.16 KRH92990.1 - 4.9 6.8 8.0 14 5.3 5.5 1.7 1 1 0 1 1 1 0 Synaptobrevin DUF4441 PF14536.1 KRH92991.1 - 0.02 14.8 1.2 0.023 14.6 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Phosphodiest PF01663.17 KRH92993.1 - 2.3e-05 23.9 0.5 7.9e-05 22.1 0.4 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KRH92993.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KRH92993.1 - 0.034 13.3 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Ribosomal_L18p PF00861.17 KRH92994.1 - 4.7e-29 101.0 0.6 7.2e-29 100.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KRH92994.1 - 3e-15 56.5 4.0 3e-15 56.5 2.8 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region RRM_1 PF00076.17 KRH92995.1 - 0.0082 15.7 0.0 0.0098 15.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92995.1 - 0.054 13.4 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH92996.1 - 1e-06 28.5 0.0 0.0026 17.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KRH92996.1 - 1.2e-06 28.0 0.0 0.0013 18.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH92996.1 - 0.00079 19.3 0.0 0.17 11.8 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PTPA PF03095.10 KRH92997.1 - 9.4e-47 159.6 2.1 9.4e-38 130.0 0.1 2.0 2 0 0 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein DUF3432 PF11914.3 KRH92997.1 - 0.33 11.0 15.6 4.4 7.3 10.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) POP1 PF06978.6 KRH92999.1 - 3.4e-11 43.1 10.6 4.3e-07 29.7 2.8 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Pkinase PF00069.20 KRH93000.1 - 1.3e-39 135.9 0.3 1.9e-39 135.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93000.1 - 1.5e-25 89.7 0.1 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KRH93000.1 - 0.00018 20.6 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KRH93000.1 - 0.0023 16.8 2.2 0.0023 16.8 1.5 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 KRH93000.1 - 0.013 15.2 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family YmgB PF10798.3 KRH93000.1 - 0.24 11.2 1.4 0.86 9.4 0.7 2.1 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR DUF3930 PF13067.1 KRH93005.1 - 0.065 13.0 4.5 0.24 11.2 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3930) ATP-synt_8 PF00895.15 KRH93005.1 - 0.26 11.5 0.2 0.26 11.5 0.1 4.7 4 1 0 4 4 4 0 ATP synthase protein 8 NfeD PF01957.13 KRH93006.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.0 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding Scs3p PF10261.4 KRH93006.1 - 6.9 5.6 12.1 34 3.3 8.4 2.1 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM UCH PF00443.24 KRH93007.1 - 1.6e-35 122.5 26.3 1.6e-35 122.5 18.2 3.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH93007.1 - 1.8e-13 50.6 28.1 1.8e-13 50.6 19.5 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KRH93007.1 - 0.0034 17.4 2.0 0.0034 17.4 1.4 3.7 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein FYVE PF01363.16 KRH93007.1 - 0.0039 17.0 3.2 0.0039 17.0 2.2 4.4 3 1 0 3 3 3 1 FYVE zinc finger BIR PF00653.16 KRH93007.1 - 0.042 14.2 0.3 0.042 14.2 0.2 3.5 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Mem_trans PF03547.13 KRH93007.1 - 0.5 8.6 3.0 0.88 7.7 2.1 1.5 1 0 0 1 1 1 0 Membrane transport protein DUF2201_N PF13203.1 KRH93007.1 - 0.75 8.9 4.1 1.3 8.1 2.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Trypan_PARP PF05887.6 KRH93007.1 - 5.6 6.7 9.3 1.3 8.8 4.0 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 KRH93007.1 - 8.7 5.2 8.3 0.35 9.8 1.7 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter HAD_2 PF13419.1 KRH93008.1 - 3.5e-18 66.4 0.0 4.2e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KRH93008.1 - 0.0056 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_like PF13242.1 KRH93009.1 - 0.03 14.0 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 HAD-hyrolase-like WWE PF02825.15 KRH93010.1 - 0.0061 15.9 0.1 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 WWE domain IL1 PF00340.14 KRH93010.1 - 0.06 12.7 0.1 0.06 12.7 0.1 1.2 1 0 0 1 1 1 0 Interleukin-1 / 18 DUF903 PF06004.7 KRH93011.1 - 0.00066 19.1 0.2 0.54 9.8 0.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF903) Fork_head PF00250.13 KRH93012.1 - 4.7e-18 65.0 0.6 4.7e-18 65.0 0.4 2.0 2 0 0 2 2 2 1 Fork head domain DUF448 PF04296.8 KRH93012.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) SMC_hinge PF06470.8 KRH93013.1 - 4e-24 84.8 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 KRH93013.1 - 1.4e-12 47.2 47.9 4.1e-11 42.5 33.2 3.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KRH93013.1 - 1.8e-11 44.7 22.9 1.8e-11 44.7 15.9 4.7 1 1 2 3 3 3 1 AAA domain AAA_21 PF13304.1 KRH93013.1 - 3.1e-10 40.4 11.8 3.1e-10 40.4 8.2 4.3 1 1 2 4 4 4 1 AAA domain AAA_29 PF13555.1 KRH93013.1 - 1.5e-09 37.2 0.0 3.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KRH93013.1 - 0.00011 22.4 0.2 0.00011 22.4 0.1 4.2 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 KRH93013.1 - 0.045 13.7 0.0 0.4 10.6 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 KRH93014.1 - 4.7e-25 88.4 0.5 4.7e-25 88.4 0.3 2.4 4 0 0 4 4 4 1 ABC transporter SMC_N PF02463.14 KRH93014.1 - 1.1e-11 44.4 5.9 2.4e-11 43.2 4.1 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 KRH93014.1 - 1.2e-10 41.2 15.8 2.1e-10 40.4 10.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.1 KRH93014.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KRH93014.1 - 0.073 12.2 0.1 0.073 12.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KRH93014.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family rve PF00665.21 KRH93018.1 - 5.6e-24 84.5 0.0 1.1e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 KRH93018.1 - 2.2e-22 79.4 0.2 4e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 KRH93018.1 - 0.0087 15.6 0.1 0.035 13.7 0.1 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 KRH93020.1 - 1.3e-22 80.2 0.2 2.4e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 KRH93020.1 - 1.8e-07 31.5 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93020.1 - 6.4e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH93020.1 - 5.4e-05 23.1 0.7 0.00012 22.0 0.5 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93020.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_thumb PF06817.9 KRH93020.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase thumb domain rve PF00665.21 KRH93021.1 - 4.6e-22 78.3 0.0 5.1e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93021.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF4203 PF13886.1 KRH93023.1 - 8.5e-07 28.6 30.1 4.5e-06 26.2 20.7 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2198 PF09964.4 KRH93023.1 - 0.018 14.8 4.8 0.018 14.8 3.3 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) DWNN PF08783.6 KRH93025.1 - 5.8e-16 58.2 0.1 1.2e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KRH93025.1 - 1.6e-06 27.5 4.0 4.9e-06 25.9 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_4 PF15227.1 KRH93025.1 - 0.00013 21.7 9.7 0.00013 21.7 6.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KRH93025.1 - 0.00052 19.6 4.0 0.002 17.8 2.8 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KRH93025.1 - 0.0035 16.9 7.5 0.0035 16.9 5.2 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KRH93025.1 - 0.0046 16.7 3.7 0.01 15.5 2.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 KRH93025.1 - 0.0051 16.6 5.6 0.0051 16.6 3.9 2.8 3 0 0 3 3 3 1 Ring finger domain zf-CCHC PF00098.18 KRH93025.1 - 0.011 15.6 3.4 0.011 15.6 2.3 2.3 3 0 0 3 3 2 0 Zinc knuckle zf-C3HC4_2 PF13923.1 KRH93025.1 - 0.012 15.6 10.1 0.012 15.6 7.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH93025.1 - 0.015 14.9 8.6 0.015 14.9 5.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 KRH93025.1 - 0.14 11.9 0.5 0.14 11.9 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 KRH93025.1 - 2.4 7.9 19.3 0.18 11.5 8.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DnaJ PF00226.26 KRH93026.1 - 5.5e-15 54.8 0.9 9e-15 54.1 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain RFPL3_antisense PF10489.4 KRH93026.1 - 0.041 13.6 1.7 4.7 7.0 0.0 2.2 1 1 1 2 2 2 0 Ret finger protein-like 3 antisense HAD_2 PF13419.1 KRH93027.1 - 1.6e-21 77.3 0.0 2.3e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 KRH93027.1 - 0.0019 17.8 1.7 0.084 12.5 1.2 2.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_PPase PF12689.2 KRH93027.1 - 0.013 15.1 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Acid Phosphatase Aminotran_5 PF00266.14 KRH93027.1 - 0.1 11.3 0.1 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V AAA PF00004.24 KRH93028.1 - 2.7e-45 153.8 0.1 7.1e-45 152.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KRH93028.1 - 7.3e-10 39.0 0.0 2.4e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KRH93028.1 - 9.3e-07 28.6 0.1 6e-06 26.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KRH93028.1 - 1.2e-06 28.7 0.1 0.00051 20.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH93028.1 - 1.8e-06 28.0 0.0 0.0003 20.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KRH93028.1 - 1.1e-05 24.5 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KRH93028.1 - 0.00017 21.2 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KRH93028.1 - 0.00028 20.3 0.2 0.047 13.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KRH93028.1 - 0.0005 19.5 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KRH93028.1 - 0.0005 20.8 0.0 0.0016 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KRH93028.1 - 0.0013 17.4 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 KRH93028.1 - 0.0015 18.1 0.3 0.0046 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KRH93028.1 - 0.0015 18.3 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KRH93028.1 - 0.0022 17.1 0.1 0.0083 15.2 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KRH93028.1 - 0.0024 17.0 0.1 0.0067 15.6 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 KRH93028.1 - 0.004 16.0 0.9 0.0053 15.6 0.0 1.6 2 0 0 2 2 1 1 Parvovirus non-structural protein NS1 KaiC PF06745.8 KRH93028.1 - 0.0042 16.2 0.2 0.028 13.5 0.0 2.2 1 1 1 2 2 2 1 KaiC Arch_ATPase PF01637.13 KRH93028.1 - 0.0047 16.6 0.2 0.031 13.9 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 KRH93028.1 - 0.0052 17.0 0.1 0.025 14.8 0.0 2.2 1 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KRH93028.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KRH93028.1 - 0.0074 15.9 0.0 0.2 11.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.1 KRH93028.1 - 0.0075 15.8 0.4 0.028 14.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KRH93028.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KRH93028.1 - 0.0097 15.1 0.1 0.028 13.6 0.1 1.8 1 1 0 1 1 1 1 PhoH-like protein DUF815 PF05673.8 KRH93028.1 - 0.011 14.6 0.0 0.03 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KRH93028.1 - 0.014 15.5 0.0 0.043 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KRH93028.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 KRH93028.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KRH93028.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KRH93028.1 - 0.027 14.2 0.1 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.7 KRH93028.1 - 0.032 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.17 KRH93028.1 - 0.071 12.9 0.3 0.34 10.7 0.0 2.3 2 1 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.1 KRH93028.1 - 0.1 12.2 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DisA-linker PF10635.4 KRH93028.1 - 0.36 10.3 5.1 6.5 6.2 0.1 2.7 3 0 0 3 3 2 0 DisA bacterial checkpoint controller linker region AAA_23 PF13476.1 KRH93028.1 - 3.4 7.9 8.7 11 6.2 2.3 3.1 2 1 0 2 2 2 0 AAA domain AgrD PF05931.6 KRH93029.1 - 2.6 7.7 9.3 0.72 9.5 2.0 2.6 2 1 1 3 3 3 0 Staphylococcal AgrD protein Skp1 PF01466.14 KRH93030.1 - 6.8e-07 29.2 0.3 1.2e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KRH93030.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain SUKH-4 PF14435.1 KRH93032.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 SUKH-4 immunity protein Methyltransf_32 PF13679.1 KRH93033.1 - 0.084 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Sin3_corepress PF08295.7 KRH93035.1 - 1.1e-11 44.3 0.4 1.1e-11 44.3 0.3 3.5 3 2 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.16 KRH93035.1 - 5.2e-07 29.1 1.6 0.0046 16.5 0.0 3.2 2 0 0 2 2 2 2 Paired amphipathic helix repeat Lsr2 PF11774.3 KRH93035.1 - 0.0058 16.5 1.8 0.026 14.4 0.3 2.4 2 0 0 2 2 2 1 Lsr2 CRAM_rpt PF07016.6 KRH93035.1 - 5.2 6.4 7.6 1.9 7.9 0.2 2.5 1 1 1 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor tRNA_int_endo PF01974.12 KRH93037.1 - 4.8e-10 39.1 0.2 1.1e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3537 PF12056.3 KRH93037.1 - 0.049 12.3 1.4 0.061 12.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Homeobox PF00046.24 KRH93038.1 - 1.4e-15 56.5 5.2 1.4e-15 56.5 3.6 1.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KRH93038.1 - 0.00031 20.3 0.8 0.00056 19.5 0.3 1.6 1 1 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 KRH93038.1 - 0.036 13.7 0.1 0.088 12.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain GerE PF00196.14 KRH93038.1 - 0.1 11.9 0.1 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family CENP-B_N PF04218.8 KRH93038.1 - 0.33 10.4 3.9 2.2 7.7 0.0 2.9 2 1 1 3 3 3 0 CENP-B N-terminal DNA-binding domain RRM_1 PF00076.17 KRH93040.1 - 4.9e-37 125.4 6.0 1e-14 53.8 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH93040.1 - 3.4e-35 119.8 2.5 8.1e-13 48.1 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH93040.1 - 1.1e-17 63.5 5.5 2.4e-07 30.4 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 KRH93040.1 - 9.4e-05 21.9 1.9 0.0075 15.8 0.4 2.6 2 0 0 2 2 2 1 BRCA1-associated protein 2 DUF1264 PF06884.6 KRH93040.1 - 0.00039 19.9 0.0 0.12 11.7 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1264) Nup35_RRM_2 PF14605.1 KRH93040.1 - 0.00049 19.8 0.2 0.46 10.2 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KRH93040.1 - 0.00057 19.5 0.3 0.32 10.7 0.0 3.9 3 2 1 4 4 4 1 Limkain b1 SseB_C PF14581.1 KRH93040.1 - 0.0036 17.1 0.0 4.8 7.0 0.0 2.8 2 1 0 2 2 2 2 SseB protein C-terminal domain RRM_2 PF04059.7 KRH93040.1 - 3.2 7.8 6.8 2.7 8.0 0.1 3.5 3 0 0 3 3 3 0 RNA recognition motif 2 Vasculin PF15337.1 KRH93041.1 - 0.045 14.2 0.0 0.045 14.2 0.0 1.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 CYTH PF01928.16 KRH93044.1 - 0.088 12.4 0.3 0.097 12.3 0.2 1.1 1 0 0 1 1 1 0 CYTH domain Scm3 PF10384.4 KRH93044.1 - 0.17 11.4 2.1 0.21 11.0 1.4 1.2 1 0 0 1 1 1 0 Centromere protein Scm3 Tubulin PF00091.20 KRH93046.1 - 4e-68 229.4 0.0 5.7e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KRH93046.1 - 9.4e-49 164.6 0.5 1.4e-48 164.0 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KRH93046.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Misat_Tub_SegII PF10644.4 KRH93046.1 - 0.039 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Hemopexin PF00045.14 KRH93048.1 - 0.39 10.4 5.4 5.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Hemopexin GRAM PF02893.15 KRH93048.1 - 0.75 9.3 4.7 3.1 7.3 0.4 2.3 1 1 1 2 2 2 0 GRAM domain RIO1 PF01163.17 KRH93051.1 - 8.7e-30 103.4 3.4 1.7e-29 102.5 2.3 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KRH93051.1 - 6.1e-06 25.5 1.6 9.4e-06 24.9 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KRH93051.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Rio2_N PF09202.6 KRH93051.1 - 0.00016 21.6 0.2 0.00037 20.5 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.9 KRH93051.1 - 0.0031 16.6 0.2 0.008 15.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KRH93051.1 - 0.012 14.6 0.4 0.11 11.5 0.3 2.3 1 1 0 1 1 1 0 Protein tyrosine kinase Pox_L5 PF04872.8 KRH93051.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Poxvirus L5 protein family Laminin_I PF06008.9 KRH93052.1 - 0.05 12.9 1.3 0.052 12.8 0.9 1.0 1 0 0 1 1 1 0 Laminin Domain I UBN2 PF14223.1 KRH93052.1 - 0.057 13.2 0.5 0.056 13.2 0.4 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3510 PF12022.3 KRH93052.1 - 0.082 13.0 0.5 0.082 13.0 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) CENP-Q PF13094.1 KRH93052.1 - 0.15 12.0 1.8 0.16 12.0 1.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KRH93052.1 - 0.27 10.7 1.7 0.28 10.7 1.2 1.0 1 0 0 1 1 1 0 IncA protein DUF2573 PF10835.3 KRH93052.1 - 0.42 10.6 2.8 0.71 9.9 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) WD40 PF00400.27 KRH93054.1 - 1.6e-15 56.2 6.4 5.5e-06 26.0 0.0 5.4 4 1 0 4 4 4 4 WD domain, G-beta repeat SHMT PF00464.14 KRH93055.1 - 2.2e-74 250.2 0.1 4.1e-74 249.3 0.1 1.4 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KRH93055.1 - 4.7e-06 25.8 0.0 6.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DHquinase_II PF01220.14 KRH93055.1 - 0.017 14.4 0.9 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 Dehydroquinase class II DEAD PF00270.24 KRH93056.1 - 1.2e-36 125.7 0.4 3e-36 124.4 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93056.1 - 1.2e-23 82.7 0.1 4.3e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KRH93056.1 - 0.003 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KRH93056.1 - 0.0061 15.0 0.3 0.043 12.2 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) AAA_22 PF13401.1 KRH93056.1 - 0.045 13.8 1.4 0.2 11.8 0.9 2.2 1 1 0 1 1 1 0 AAA domain Propep_M14 PF02244.11 KRH93056.1 - 0.052 13.2 0.9 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Acid_PPase PF12689.2 KRH93056.1 - 0.072 12.7 0.1 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase CDC45 PF02724.9 KRH93058.1 - 1.3e-05 23.4 0.0 2.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 CDC45-like protein SapB_1 PF05184.10 KRH93058.1 - 0.022 14.5 4.2 0.03 14.1 1.3 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 Fer2 PF00111.22 KRH93059.1 - 5.1e-12 45.3 0.1 6.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1364 PF07102.7 KRH93059.1 - 0.034 14.0 0.7 0.071 12.9 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) Methyltransf_23 PF13489.1 KRH93060.1 - 1.1e-12 47.9 0.1 1.4e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KRH93060.1 - 2.4e-08 34.3 0.0 6e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KRH93060.1 - 2.7e-07 30.3 0.6 3.2e-07 30.0 0.4 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KRH93060.1 - 7.7e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KRH93060.1 - 6.5e-05 23.2 0.0 0.00015 22.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KRH93060.1 - 9.5e-05 22.9 0.0 0.0002 21.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 KRH93060.1 - 0.00025 20.4 0.5 0.0031 16.8 0.1 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 KRH93060.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain VirArc_Nuclease PF12187.3 KRH93060.1 - 0.11 11.8 3.3 0.046 13.1 0.5 1.6 2 0 0 2 2 2 0 Viral/Archaeal nuclease DUF3894 PF13033.1 KRH93061.1 - 0.014 15.3 0.9 0.069 13.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) Epimerase PF01370.16 KRH93062.1 - 1.2e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KRH93062.1 - 2.1e-08 34.2 0.0 1e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KRH93062.1 - 8.4e-07 29.1 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 KRH93062.1 - 0.0016 18.6 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding RmlD_sub_bind PF04321.12 KRH93062.1 - 0.016 14.1 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 KRH93062.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RVT_1 PF00078.22 KRH93064.1 - 2.1e-17 63.1 0.0 3.3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G6PD_N PF00479.17 KRH93065.1 - 7.4e-08 32.8 1.3 0.00035 20.8 0.3 2.4 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.11 KRH93065.1 - 0.00035 19.5 0.2 0.0028 16.5 0.0 2.5 2 1 1 3 3 3 1 Glucose-6-phosphate dehydrogenase, C-terminal domain GFO_IDH_MocA PF01408.17 KRH93065.1 - 0.021 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Arf PF00025.16 KRH93066.1 - 7.7e-44 148.9 0.0 8.6e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KRH93066.1 - 1.2e-11 44.2 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KRH93066.1 - 1.8e-09 36.7 0.8 3.4e-06 25.9 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KRH93066.1 - 5.4e-08 33.3 0.0 9.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KRH93066.1 - 5.8e-07 28.8 0.0 6.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KRH93066.1 - 3e-06 26.5 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KRH93066.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KRH93066.1 - 0.0031 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF3609 PF12259.3 KRH93068.1 - 0.056 12.0 0.0 0.056 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Vpu PF00558.14 KRH93068.1 - 0.058 12.9 0.0 0.095 12.2 0.0 1.5 1 1 0 1 1 1 0 Vpu protein DUF4029 PF13221.1 KRH93068.1 - 0.071 13.4 0.2 1.9 8.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4029) EpuA PF11772.3 KRH93068.1 - 0.27 10.7 1.2 0.41 10.1 0.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Toxin_9 PF02819.10 KRH93069.1 - 0.074 13.1 0.3 0.074 13.1 0.2 2.4 2 1 0 2 2 2 0 Spider toxin lci PF12197.3 KRH93070.1 - 0.29 10.7 1.9 0.31 10.6 0.2 1.8 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein rve PF00665.21 KRH93071.1 - 2.4e-08 34.1 0.0 6.7e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH93071.1 - 0.00066 19.1 0.1 0.0014 18.0 0.1 1.7 1 1 0 1 1 1 1 Integrase core domain BIR PF00653.16 KRH93072.1 - 0.086 13.2 0.2 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain OTT_1508_deam PF14441.1 KRH93072.1 - 0.13 12.0 0.5 0.14 11.9 0.3 1.0 1 0 0 1 1 1 0 OTT_1508-like deaminase DUF3791 PF12668.2 KRH93074.1 - 0.46 10.1 3.7 0.85 9.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Ribosomal_L34e PF01199.13 KRH93075.1 - 3.8e-26 91.1 4.3 4.1e-26 91.0 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Adeno_PV PF03910.8 KRH93075.1 - 0.067 12.2 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Spc24 PF08286.6 KRH93078.1 - 0.17 11.5 1.2 0.18 11.5 0.9 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PI3_PI4_kinase PF00454.22 KRH93079.1 - 6.1e-12 45.5 0.7 8.7e-12 45.0 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TGS PF02824.16 KRH93080.1 - 3.3e-20 71.6 0.1 5.7e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KRH93080.1 - 2.2e-19 69.5 0.5 7.2e-19 67.8 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KRH93080.1 - 9.2e-14 51.0 2.1 1.1e-11 44.3 0.1 3.1 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KRH93080.1 - 2.6e-05 24.1 0.2 0.085 12.6 0.0 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KRH93080.1 - 4e-05 23.1 0.2 0.13 11.7 0.0 3.5 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KRH93080.1 - 0.00093 19.6 0.4 0.0029 18.0 0.0 2.1 3 0 0 3 3 1 1 Miro-like protein SRPRB PF09439.5 KRH93080.1 - 0.01 15.0 0.2 0.023 13.9 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 KRH93080.1 - 0.012 14.4 0.0 0.035 12.8 0.0 1.8 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 KRH93080.1 - 0.024 14.6 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KRH93080.1 - 0.033 13.4 0.7 1.5 8.0 0.1 3.0 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 KRH93080.1 - 0.039 14.1 1.0 0.43 10.7 0.0 2.8 2 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KRH93080.1 - 0.049 12.4 0.1 0.094 11.5 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain cobW PF02492.14 KRH93080.1 - 0.053 12.9 0.3 11 5.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KRH93080.1 - 0.086 13.6 0.1 0.27 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KRH93080.1 - 0.25 10.8 1.6 13 5.2 0.1 2.7 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Lip_prot_lig_C PF10437.4 KRH93081.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus RNase_PH PF01138.16 KRH93082.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Elf1 PF05129.8 KRH93083.1 - 1.2e-20 73.0 1.4 1.3e-20 72.8 1.0 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KRH93083.1 - 0.0013 18.8 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-LITAF-like PF10601.4 KRH93083.1 - 0.0093 15.8 2.0 0.15 11.9 1.6 2.0 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain Cytochrome_C7 PF14522.1 KRH93083.1 - 0.012 15.2 0.2 0.013 15.1 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c7 Zn-ribbon_8 PF09723.5 KRH93083.1 - 0.014 15.3 1.0 0.024 14.6 0.7 1.3 1 0 0 1 1 1 0 Zinc ribbon domain DUF2387 PF09526.5 KRH93083.1 - 0.022 14.6 0.3 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Cytochrom_c3_2 PF14537.1 KRH93083.1 - 0.04 14.2 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c3 zinc_ribbon_4 PF13717.1 KRH93083.1 - 0.046 13.4 2.1 0.1 12.3 1.5 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_3 PF14369.1 KRH93083.1 - 0.046 13.7 0.8 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger zinc_ribbon_5 PF13719.1 KRH93083.1 - 0.089 12.3 2.1 0.2 11.2 1.6 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin PF00301.15 KRH93083.1 - 0.11 12.3 0.4 4.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin OrfB_Zn_ribbon PF07282.6 KRH93083.1 - 0.15 11.7 1.2 0.2 11.3 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.3 KRH93083.1 - 0.49 10.6 2.3 0.83 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPG_I PF00867.13 KRH93084.1 - 1e-13 51.0 0.7 4.1e-12 46.0 0.1 3.1 3 1 0 3 3 3 1 XPG I-region 5_3_exonuc_N PF02739.11 KRH93084.1 - 0.0017 17.7 0.7 0.011 15.1 0.0 2.1 1 1 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain TrwC PF08751.6 KRH93084.1 - 0.0032 16.9 0.4 0.0053 16.2 0.3 1.3 1 0 0 1 1 1 1 TrwC relaxase HHH PF00633.18 KRH93084.1 - 0.028 14.1 1.7 0.16 11.6 0.2 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.15 KRH93084.1 - 0.038 14.2 2.5 0.091 12.9 0.2 2.9 2 2 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Homez PF11569.3 KRH93084.1 - 0.23 10.5 2.9 0.19 10.7 0.3 2.0 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Sec7 PF01369.15 KRH93085.1 - 2.6e-30 105.5 16.4 9.6e-30 103.6 7.3 3.6 2 1 0 2 2 2 1 Sec7 domain BBS2_N PF14781.1 KRH93086.1 - 0.3 10.6 3.4 1.2 8.7 1.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF4491 PF14898.1 KRH93087.1 - 6 7.0 7.8 7.2 6.8 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Transport_MerF PF11431.3 KRH93087.1 - 7.5 6.2 14.4 2.4 7.8 1.6 3.0 1 1 2 3 3 3 0 Membrane transport protein MerF HEAT_2 PF13646.1 KRH93088.1 - 8.1e-09 35.6 0.0 0.00043 20.5 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KRH93088.1 - 2e-05 24.3 0.3 5 7.4 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KRH93088.1 - 0.0017 18.7 0.0 6.3 7.4 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat PC_rep PF01851.17 KRH93088.1 - 0.0036 17.4 2.3 0.34 11.2 0.1 4.2 4 0 0 4 4 4 1 Proteasome/cyclosome repeat RICTOR_V PF14668.1 KRH93088.1 - 0.028 14.3 0.3 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF2462 PF09495.5 KRH93089.1 - 0.045 14.4 1.1 0.051 14.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) DUF3807 PF12720.2 KRH93090.1 - 0.44 10.6 4.3 0.94 9.6 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) tRNA-synt_2 PF00152.15 KRH93092.1 - 6.9e-61 205.8 2.0 7.8e-61 205.6 0.8 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KRH93092.1 - 1.5e-07 31.1 0.1 3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KRH93092.1 - 0.00052 19.2 0.9 0.079 12.1 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-C2H2 PF00096.21 KRH93096.1 - 1.3e-05 25.2 14.9 0.0045 17.2 0.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KRH93096.1 - 2e-05 24.5 13.7 0.0018 18.4 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KRH93096.1 - 0.00033 20.7 3.2 0.00033 20.7 2.2 3.7 3 0 0 3 3 3 1 Zinc-finger double domain Ogr_Delta PF04606.7 KRH93096.1 - 0.019 14.5 0.2 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 KRH93096.1 - 0.25 11.2 9.0 2 8.4 2.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger ParA PF10609.4 KRH93097.1 - 5.3e-05 23.0 0.2 0.00015 21.5 0.1 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like OstA_2 PF13100.1 KRH93097.1 - 0.034 13.4 0.1 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 OstA-like protein AARP2CN PF08142.7 KRH93098.1 - 0.00019 20.9 0.0 0.001 18.5 0.0 2.4 1 1 0 1 1 1 1 AARP2CN (NUC121) domain PilP PF04351.8 KRH93098.1 - 0.9 9.4 9.1 0.48 10.3 0.4 2.6 2 0 0 2 2 2 0 Pilus assembly protein, PilP Cag12 PF13117.1 KRH93100.1 - 0.03 14.2 1.4 0.068 13.0 0.8 1.7 1 1 1 2 2 2 0 Cag pathogenicity island protein Cag12 ING PF12998.2 KRH93100.1 - 0.033 14.4 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-CCHC PF00098.18 KRH93101.1 - 4.3e-06 26.3 1.5 6.5e-06 25.8 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KRH93101.1 - 0.058 13.1 1.7 0.11 12.2 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 KRH93101.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 KRH93101.1 - 0.18 11.4 1.2 0.35 10.5 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Rpr2 PF04032.11 KRH93101.1 - 0.3 10.9 5.2 0.36 10.7 3.6 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TFIID-18kDa PF02269.11 KRH93103.1 - 2.7e-21 75.1 1.5 3.3e-21 74.8 1.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit SRP54 PF00448.17 KRH93105.1 - 8.6e-67 224.3 0.1 8.6e-67 224.3 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KRH93105.1 - 4.6e-20 71.8 0.4 4.6e-20 71.8 0.2 3.1 2 1 1 3 3 3 1 Signal peptide binding domain cobW PF02492.14 KRH93105.1 - 2.7e-08 33.4 0.4 6.8e-08 32.1 0.3 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KRH93105.1 - 3.9e-05 23.3 0.1 0.00015 21.4 0.1 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54_N PF02881.14 KRH93105.1 - 0.0004 20.4 5.3 0.0004 20.4 3.7 3.0 3 1 0 3 3 3 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 KRH93105.1 - 0.00092 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KRH93105.1 - 0.0064 16.6 0.8 0.018 15.2 0.1 2.2 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 KRH93105.1 - 0.012 14.4 2.0 0.016 13.9 0.0 2.2 3 0 0 3 3 3 0 ArgK protein AAA_30 PF13604.1 KRH93105.1 - 0.02 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KRH93105.1 - 0.032 13.4 3.6 0.6 9.2 0.0 3.4 1 1 1 3 3 3 0 Protein of unknown function, DUF258 RsmJ PF04378.8 KRH93105.1 - 0.08 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ AAA_17 PF13207.1 KRH93105.1 - 0.097 13.4 0.9 0.25 12.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 KRH93105.1 - 0.21 11.3 0.0 0.47 10.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain FliL PF03748.9 KRH93105.1 - 5.9 6.9 8.3 1.7 8.6 0.0 3.2 3 1 0 3 3 2 0 Flagellar basal body-associated protein FliL Microtub_assoc PF07989.6 KRH93105.1 - 8.3 6.3 15.7 5.7 6.8 0.2 4.2 4 0 0 4 4 4 0 Microtubule associated FYRN PF05964.9 KRH93108.1 - 3.6e-09 35.9 1.2 4.1e-09 35.7 0.1 1.6 2 0 0 2 2 2 1 F/Y-rich N-terminus Cbl_N PF02262.11 KRH93108.1 - 0.0031 17.2 1.5 0.0055 16.4 1.0 1.5 1 1 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 BA14K PF07886.6 KRH93108.1 - 1 9.0 3.6 0.35 10.5 0.3 1.8 2 0 0 2 2 2 0 BA14K-like protein 6PGD PF00393.14 KRH93110.1 - 4.4e-29 101.6 2.1 5.5e-29 101.3 1.5 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KRH93110.1 - 6.7e-29 100.8 0.0 3.4e-19 69.2 0.0 2.4 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KRH93110.1 - 0.00033 20.1 0.0 0.00089 18.7 0.0 1.8 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KRH93110.1 - 0.0021 18.4 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KRH93110.1 - 0.0033 17.1 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KRH93110.1 - 0.0092 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KRH93110.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KRH93110.1 - 0.049 12.7 0.0 0.48 9.5 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_24 PF13412.1 KRH93110.1 - 0.065 12.6 0.4 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HSP90 PF00183.13 KRH93113.1 - 5.2e-91 305.6 17.0 6.2e-91 305.4 11.8 1.0 1 0 0 1 1 1 1 Hsp90 protein FAD_binding_7 PF03441.9 KRH93114.1 - 5.5e-10 38.9 2.9 3.1e-09 36.4 1.7 2.1 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase NABP PF07990.7 KRH93114.1 - 0.95 8.6 16.4 0.27 10.4 6.3 2.1 1 1 1 2 2 2 0 Nucleic acid binding protein NABP DUF4451 PF14616.1 KRH93116.1 - 3.2e-23 81.8 16.3 8.9e-23 80.4 10.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) zf-C2H2_jaz PF12171.3 KRH93116.1 - 0.032 14.3 5.2 1.7 8.8 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KRH93116.1 - 2.8 8.1 6.4 1.5 8.9 2.3 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KRH93116.1 - 5 7.6 14.0 0.18 12.2 1.3 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger DUF1128 PF06569.6 KRH93117.1 - 0.0017 18.0 0.3 0.0017 18.0 0.2 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1128) MbeD_MobD PF04899.7 KRH93117.1 - 0.0048 16.7 0.2 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 MbeD/MobD like MCPsignal PF00015.16 KRH93117.1 - 0.013 15.0 1.3 0.026 14.0 0.9 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 KRH93117.1 - 0.037 13.8 0.2 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KRH93117.1 - 0.05 13.8 3.7 0.15 12.3 0.5 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 KRH93117.1 - 0.064 13.4 5.2 0.16 12.1 0.7 2.5 2 0 0 2 2 2 0 Syntaxin FlaC_arch PF05377.6 KRH93117.1 - 0.12 12.2 8.4 2 8.3 3.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 KRH93117.1 - 0.14 11.8 6.0 0.33 10.6 1.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Ribosomal_S8 PF00410.14 KRH93117.1 - 2.6 7.9 6.5 0.63 9.8 0.2 2.5 3 0 0 3 3 3 0 Ribosomal protein S8 DUF462 PF04315.7 KRH93120.1 - 0.042 13.2 0.2 0.084 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF462 Kinesin PF00225.18 KRH93121.1 - 3e-66 223.4 16.5 3.6e-41 140.9 6.7 2.4 1 1 1 2 2 2 2 Kinesin motor domain Coat_F PF07875.7 KRH93121.1 - 0.91 9.7 3.9 3.2 7.9 0.0 3.2 3 0 0 3 3 3 0 Coat F domain RNA_pol_Rpb2_3 PF04565.11 KRH93124.1 - 6.4e-19 67.4 0.0 1.7e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KRH93124.1 - 0.00097 18.9 0.0 0.0033 17.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Neur_chan_memb PF02932.11 KRH93124.1 - 3.8 7.3 23.2 0.86 9.4 7.5 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DEAD_2 PF06733.10 KRH93125.1 - 1.2e-37 128.9 14.4 2.3e-23 82.4 2.0 2.8 2 1 0 3 3 3 2 DEAD_2 DEAD PF00270.24 KRH93125.1 - 0.00017 21.0 0.9 0.064 12.7 0.0 3.0 3 1 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KRH93125.1 - 0.00028 20.7 14.7 0.0015 18.4 0.0 3.6 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KRH93125.1 - 0.009 16.1 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KRH93125.1 - 0.011 15.0 1.0 1.8 7.7 0.2 2.4 2 0 0 2 2 2 0 PhoH-like protein Zot PF05707.7 KRH93125.1 - 0.016 14.6 0.3 0.14 11.5 0.0 2.4 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) Adaptin_N PF01602.15 KRH93126.1 - 0.0092 14.3 1.6 0.014 13.7 1.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region 5_nucleotid PF05761.9 KRH93126.1 - 0.039 12.4 0.1 0.075 11.5 0.0 1.5 1 1 0 1 1 1 0 5' nucleotidase family DUF496 PF04363.7 KRH93126.1 - 0.065 13.0 5.0 3.2 7.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF496) RVT_1 PF00078.22 KRH93127.1 - 8.1e-11 41.6 0.3 1.3e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OS-D PF03392.8 KRH93128.1 - 0.015 15.2 4.0 0.018 15.0 2.8 1.1 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Zn-ribbon_8 PF09723.5 KRH93128.1 - 0.11 12.4 2.6 0.18 11.7 1.8 1.3 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KRH93128.1 - 1.3 8.3 4.9 1.4 8.2 1.2 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Cys_rich_KTR PF14205.1 KRH93128.1 - 1.4 8.3 8.7 0.94 8.9 3.7 2.2 1 1 1 2 2 2 0 Cysteine-rich KTR DUF1027 PF06265.6 KRH93129.1 - 0.0076 16.0 0.2 0.0084 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1027) ARL2_Bind_BART PF11527.3 KRH93129.1 - 0.018 14.7 0.6 0.021 14.6 0.4 1.1 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Arf PF00025.16 KRH93131.1 - 4.4e-22 78.1 0.0 5e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KRH93131.1 - 1.2e-08 34.4 0.0 2e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KRH93131.1 - 2e-08 33.7 0.0 2.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KRH93131.1 - 2.4e-08 33.3 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KRH93131.1 - 2.5e-08 34.4 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KRH93131.1 - 3.7e-06 26.8 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KRH93131.1 - 1.7e-05 23.7 0.1 0.00083 18.1 0.0 2.1 1 1 0 2 2 2 1 G-protein alpha subunit IIGP PF05049.8 KRH93131.1 - 0.0094 14.7 0.0 0.016 14.0 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 KRH93131.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KRH93131.1 - 0.021 14.5 0.0 0.28 10.8 0.0 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KRH93131.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 KRH93131.1 - 0.04 13.7 0.3 1.4 8.6 0.2 2.3 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 KRH93131.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KRH93131.1 - 0.056 12.9 0.3 0.22 11.0 0.1 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 KRH93131.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 KRH93131.1 - 0.069 13.0 0.1 0.16 11.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain Septin PF00735.13 KRH93131.1 - 0.087 11.8 0.0 0.28 10.1 0.0 1.8 1 1 0 1 1 1 0 Septin AAA_22 PF13401.1 KRH93131.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KRH93131.1 - 0.18 12.6 1.0 0.51 11.1 0.3 2.1 1 1 0 2 2 2 0 AAA domain DDE_3 PF13358.1 KRH93132.1 - 2.5e-08 33.8 0.4 1.2e-07 31.6 0.2 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease NPL4 PF05021.10 KRH93135.1 - 3.1e-07 29.8 2.7 4.5e-07 29.3 1.0 1.7 1 1 1 2 2 2 1 NPL4 family zf-RanBP PF00641.13 KRH93135.1 - 3.4e-05 22.8 3.2 6.5e-05 21.9 2.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DDE_3 PF13358.1 KRH93137.1 - 4.4e-19 68.6 0.2 6.1e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 KRH93137.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain HsdM_N PF12161.3 KRH93137.1 - 0.038 14.4 0.2 0.053 13.9 0.2 1.3 1 1 0 1 1 1 0 HsdM N-terminal domain EFhand_Ca_insen PF08726.5 KRH93140.1 - 0.028 14.3 0.5 0.096 12.6 0.4 1.9 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Mak16 PF04874.9 KRH93141.1 - 0.04 14.0 1.7 1.9 8.6 0.0 2.1 2 0 0 2 2 2 0 Mak16 protein C-terminal region Radial_spoke PF04712.7 KRH93141.1 - 0.042 12.5 1.2 0.06 12.0 0.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DEC-1_N PF04625.8 KRH93141.1 - 0.26 9.9 2.5 0.46 9.1 1.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region WD40 PF00400.27 KRH93142.1 - 1.8e-21 75.1 7.3 7.7e-07 28.7 0.0 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KRH93142.1 - 0.022 14.2 0.4 3.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.1 KRH93142.1 - 0.046 13.3 0.0 0.62 9.6 0.0 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal SSURE PF11966.3 KRH93142.1 - 0.078 12.5 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Fibronectin-binding repeat Kelch_6 PF13964.1 KRH93142.1 - 1.3 9.3 4.2 31 4.9 0.1 4.2 5 0 0 5 5 5 0 Kelch motif CAF1A PF12253.3 KRH93143.1 - 9.2e-06 25.6 5.8 2.2e-05 24.4 4.0 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A BPL_N PF09825.4 KRH93143.1 - 0.12 11.1 3.6 0.14 10.8 2.5 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal PA28_alpha PF02251.13 KRH93146.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit RVT_1 PF00078.22 KRH93147.1 - 7.8e-15 54.8 0.1 9.6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tbf5 PF06331.7 KRH93147.1 - 0.011 15.5 0.1 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Coatamer_beta_C PF07718.7 KRH93148.1 - 1.1e-13 51.0 0.5 2.4e-13 49.9 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KRH93148.1 - 1.1e-13 51.0 1.7 3.7e-13 49.3 1.2 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform RVT_1 PF00078.22 KRH93149.1 - 1.6e-21 76.6 0.4 3.9e-21 75.3 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93149.1 - 2.7e-20 72.6 0.1 3.1e-19 69.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 KRH93149.1 - 4.9e-05 23.7 0.0 0.00016 22.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93149.1 - 6.5e-05 22.6 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH93149.1 - 0.00035 20.4 2.2 0.00083 19.2 0.0 2.9 4 0 0 4 4 3 1 Retroviral aspartyl protease RVT_thumb PF06817.9 KRH93149.1 - 0.00091 18.7 0.2 0.0032 17.0 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase thumb domain MULE PF10551.4 KRH93149.1 - 0.0019 18.3 0.1 0.024 14.7 0.0 2.6 2 0 0 2 2 2 1 MULE transposase domain Asp_protease PF09668.5 KRH93149.1 - 0.0049 16.4 0.1 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.1 KRH93149.1 - 0.016 14.7 0.1 0.085 12.4 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain RVP_2 PF08284.6 KRH93149.1 - 0.032 14.1 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF1758 PF05585.7 KRH93149.1 - 0.068 12.7 2.7 0.2 11.2 0.2 2.7 3 0 0 3 3 3 0 Putative peptidase (DUF1758) Uteroglobin PF01099.12 KRH93149.1 - 0.33 10.7 3.6 2.2 8.1 0.1 3.6 3 0 0 3 3 3 0 Uteroglobin family Elongin_A PF06881.6 KRH93151.1 - 0.31 11.4 2.2 0.4 11.0 1.5 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_1 PF00078.22 KRH93152.1 - 3.5e-09 36.3 0.1 5.8e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RdRP_1 PF00680.15 KRH93152.1 - 0.022 13.0 0.1 0.022 12.9 0.1 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase BH4 PF02180.12 KRH93152.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 rve PF00665.21 KRH93153.1 - 2.1e-21 76.2 0.1 1.7e-20 73.3 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH93153.1 - 3.2e-18 65.8 0.2 3.2e-18 65.8 0.2 2.4 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS240 PF13610.1 KRH93153.1 - 0.0005 20.0 0.4 0.0021 17.9 0.3 2.1 1 0 0 1 1 1 1 DDE domain RVP PF00077.15 KRH93153.1 - 0.00055 19.8 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 KRH93153.1 - 0.074 12.5 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain tRNA-synt_2b PF00587.20 KRH93154.1 - 4.5e-56 189.1 1.3 8.4e-56 188.2 0.9 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KRH93154.1 - 4.9e-15 55.2 1.2 4.9e-15 55.2 0.8 2.1 2 0 0 2 2 2 1 Anticodon binding domain Ndc1_Nup PF09531.5 KRH93154.1 - 1.5 7.1 5.7 2.2 6.6 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CamS PF07537.6 KRH93155.1 - 0.041 12.9 0.3 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor Peptidase_M16 PF00675.15 KRH93159.1 - 3.5e-22 78.7 0.0 7e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KRH93159.1 - 0.018 14.7 0.1 0.12 12.0 0.1 2.3 1 1 0 1 1 1 0 Peptidase M16 inactive domain NYD-SP12_N PF15015.1 KRH93161.1 - 0.011 14.0 0.0 0.011 14.0 0.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal POC1 PF10450.4 KRH93162.1 - 0.0018 17.0 0.3 0.002 16.9 0.2 1.0 1 0 0 1 1 1 1 POC1 chaperone Peptidase_M22 PF00814.20 KRH93163.1 - 1.4e-76 257.4 0.1 1.7e-76 257.2 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Svf1 PF08622.5 KRH93163.1 - 0.088 11.7 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Svf1-like AKNA PF12443.3 KRH93164.1 - 0.093 12.7 1.0 0.18 11.8 0.7 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor SNARE PF05739.14 KRH93166.1 - 1.2e-07 31.3 2.4 2.8e-07 30.1 1.7 1.6 1 0 0 1 1 1 1 SNARE domain CTP_transf_1 PF01148.15 KRH93167.1 - 1.9e-54 185.0 25.2 2.4e-54 184.7 17.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PSS PF03034.10 KRH93168.1 - 3.5e-54 184.1 27.9 1.8e-47 162.1 12.7 3.9 4 1 1 5 5 5 3 Phosphatidyl serine synthase HMG_box PF00505.14 KRH93169.1 - 9.4e-18 64.2 23.5 4.3e-09 36.5 4.9 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KRH93169.1 - 8.6e-17 61.2 21.1 4e-09 36.6 5.0 2.6 2 0 0 2 2 2 2 HMG-box domain DUF3128 PF11326.3 KRH93169.1 - 0.01 15.9 1.3 0.01 15.9 0.9 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3128) DUF1289 PF06945.8 KRH93169.1 - 0.33 10.4 3.7 0.96 8.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) YABBY PF04690.8 KRH93169.1 - 7.3 6.7 8.4 0.59 10.3 1.6 2.2 1 1 2 3 3 3 0 YABBY protein COX4 PF02936.9 KRH93169.1 - 9 6.0 13.7 1 9.1 0.6 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV DUF3591 PF12157.3 KRH93170.1 - 2.4e-38 131.7 7.9 2.5e-34 118.4 5.1 3.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.20 KRH93170.1 - 1.2e-16 60.4 1.4 6.5e-16 58.0 0.0 3.1 3 0 0 3 3 3 1 Bromodomain zf-CCHC_6 PF15288.1 KRH93170.1 - 0.00014 21.4 2.2 0.00036 20.1 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle TLC PF03219.9 KRH93171.1 - 1.5e-57 195.2 36.5 2.5e-57 194.4 25.3 1.3 1 1 0 1 1 1 1 TLC ATP/ADP transporter OAD_gamma PF04277.8 KRH93171.1 - 0.013 15.8 0.2 1.3 9.4 0.1 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Adeno_E3_14_5 PF04834.7 KRH93171.1 - 0.11 12.8 3.8 0.15 12.5 0.2 2.9 2 0 0 2 2 2 0 Early E3 14.5 kDa protein WD40 PF00400.27 KRH93174.1 - 1.3e-26 91.4 3.2 3.6e-08 32.9 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KRH93174.1 - 0.002 17.8 1.4 0.4 10.3 0.0 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KRH93174.1 - 0.012 15.1 0.0 1.1 8.6 0.0 2.7 1 1 1 2 2 2 0 PQQ-like domain Parvo_NS1 PF01057.12 KRH93174.1 - 0.023 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bromodomain PF00439.20 KRH93175.1 - 1.5e-38 130.5 5.0 6e-19 67.7 0.4 2.6 2 0 0 2 2 2 2 Bromodomain DUF3993 PF13158.1 KRH93175.1 - 0.042 13.6 0.7 0.12 12.2 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3993) Mgr1 PF08602.5 KRH93175.1 - 0.18 10.7 7.8 0.68 8.8 0.5 2.2 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit AsnA PF03590.10 KRH93176.1 - 1.2e-28 100.1 3.1 2.4e-22 79.5 0.4 2.1 1 1 1 2 2 2 2 Aspartate-ammonia ligase Proteasome PF00227.21 KRH93179.1 - 8.1e-30 103.5 0.0 9e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 KRH93180.1 - 1.3e-29 102.9 0.2 1.7e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Uds1 PF15456.1 KRH93180.1 - 0.078 12.9 0.4 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 Up-regulated During Septation RVP PF00077.15 KRH93182.1 - 9.8e-05 22.2 0.1 0.00038 20.3 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH93182.1 - 0.00012 22.5 0.0 0.00051 20.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 KRH93182.1 - 0.00031 20.7 4.4 0.0089 16.0 0.1 3.0 2 1 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 KRH93182.1 - 0.02 14.7 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 KRH93182.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative peptidase (DUF1758) RAMPs PF03787.10 KRH93182.1 - 1.2 8.8 8.2 1.5 8.5 5.2 1.5 1 1 0 1 1 1 0 RAMP superfamily Lge1 PF11488.3 KRH93182.1 - 2.8 8.1 9.0 6.3 7.0 0.1 3.4 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 Ank_3 PF13606.1 KRH93183.1 - 0.056 13.7 0.0 0.6 10.5 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat UNC-93 PF05978.11 KRH93183.1 - 0.11 12.0 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Ank PF00023.25 KRH93183.1 - 0.12 12.1 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Sec20 PF03908.8 KRH93185.1 - 4.2e-08 32.7 4.3 6e-08 32.2 2.4 1.6 1 1 1 2 2 2 1 Sec20 B-block_TFIIIC PF04182.7 KRH93185.1 - 0.069 12.9 1.2 0.12 12.2 0.3 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Pkinase PF00069.20 KRH93186.1 - 3.6e-26 91.8 0.0 4.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93186.1 - 1.7e-07 30.5 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KRH93186.1 - 0.026 14.2 0.0 5 6.7 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family TPR_11 PF13414.1 KRH93187.1 - 8.6e-24 82.9 1.8 4.9e-18 64.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KRH93187.1 - 3.5e-15 54.8 5.1 9.6e-05 21.8 0.2 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KRH93187.1 - 3.5e-13 48.3 2.8 0.00019 21.0 0.1 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KRH93187.1 - 1.5e-10 40.4 1.6 0.0021 18.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KRH93187.1 - 1.7e-07 30.5 0.1 0.027 14.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KRH93187.1 - 2.7e-06 27.9 0.0 0.0045 17.6 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KRH93187.1 - 5.8e-06 26.5 0.0 0.033 14.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KRH93187.1 - 6.2e-06 25.6 10.4 0.039 13.7 0.2 5.1 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KRH93187.1 - 1.1e-05 25.2 0.1 0.0093 15.8 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KRH93187.1 - 2.5e-05 24.4 1.0 0.73 10.4 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KRH93187.1 - 0.0018 18.0 0.1 0.045 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KRH93187.1 - 0.0042 17.5 0.0 2.4 9.0 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KRH93187.1 - 0.0066 16.3 2.7 0.15 11.9 0.3 3.2 2 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 KRH93187.1 - 0.0089 15.6 0.2 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 DUF2225 PF09986.4 KRH93187.1 - 0.022 14.2 3.9 0.064 12.7 1.7 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 KRH93187.1 - 0.042 13.7 2.5 11 6.0 0.7 3.2 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 KRH93187.1 - 0.074 13.2 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fib_alpha PF08702.5 KRH93187.1 - 0.31 11.1 2.7 0.39 10.8 0.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tyr_Deacylase PF02580.11 KRH93188.1 - 5.3e-28 97.8 0.1 7.4e-28 97.3 0.1 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF3000 PF11452.3 KRH93190.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) rve PF00665.21 KRH93192.1 - 3.7e-12 46.4 0.0 8.1e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH93193.1 - 4.3e-05 22.9 0.4 7.9e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH93193.1 - 0.0007 19.1 0.1 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain G_glu_transpept PF01019.16 KRH93193.1 - 0.019 13.5 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase HxlR PF01638.12 KRH93193.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix zf-C2H2 PF00096.21 KRH93194.1 - 1.1e-07 31.7 10.4 0.00063 19.9 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KRH93194.1 - 6.7e-07 29.2 6.9 0.0033 17.6 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KRH93194.1 - 6e-06 26.2 16.5 8.3e-06 25.8 3.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain DUF4249 PF14054.1 KRH93194.1 - 0.028 13.7 5.1 0.039 13.3 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) ORC6 PF05460.8 KRH93195.1 - 0.0044 16.1 9.7 0.0069 15.5 6.8 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Dsh_C PF12316.3 KRH93195.1 - 0.14 12.2 5.2 0.2 11.7 3.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Mem_trans PF03547.13 KRH93195.1 - 0.19 9.9 0.6 0.21 9.8 0.4 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4512 PF14975.1 KRH93195.1 - 0.59 10.9 0.1 0.59 10.9 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) DDHD PF02862.12 KRH93195.1 - 1.4 8.6 14.8 2.5 7.8 10.3 1.4 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 KRH93195.1 - 1.9 7.4 7.2 3.1 6.7 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 KRH93195.1 - 1.9 8.1 12.4 3.9 7.1 8.6 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region CobT PF06213.7 KRH93195.1 - 3.3 6.7 17.5 4.8 6.2 12.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.11 KRH93195.1 - 3.7 7.3 6.0 5.6 6.7 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin PF00085.15 KRH93196.1 - 5.2e-11 42.1 0.1 4.6e-10 39.1 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 KRH93196.1 - 1.1e-05 25.3 7.1 8.6e-05 22.4 0.6 3.9 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KRH93196.1 - 7.5e-05 22.7 0.0 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KRH93196.1 - 0.00044 20.4 0.2 0.0027 17.8 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KRH93196.1 - 0.0014 18.2 0.1 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_4 PF13462.1 KRH93196.1 - 0.0025 17.8 1.0 0.0055 16.7 0.0 2.1 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 KRH93196.1 - 0.0032 17.0 1.6 0.14 11.6 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin Glutaredoxin PF00462.19 KRH93196.1 - 0.004 17.0 0.4 0.042 13.8 0.0 2.6 2 0 0 2 2 2 1 Glutaredoxin Redoxin PF08534.5 KRH93196.1 - 0.0062 16.0 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 Redoxin Tmemb_55A PF09788.4 KRH93196.1 - 0.0086 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 55A DUF836 PF05768.9 KRH93196.1 - 0.062 13.5 0.3 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Asp_protease_2 PF13650.1 KRH93199.1 - 4.2e-08 33.5 0.0 8.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KRH93199.1 - 1.8e-06 27.9 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH93199.1 - 8.5e-06 25.6 0.7 3.5e-05 23.6 0.0 2.4 3 1 0 3 3 3 1 Retroviral aspartyl protease DUF1758 PF05585.7 KRH93199.1 - 0.0083 15.7 0.0 0.028 13.9 0.0 2.0 1 1 0 1 1 1 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.1 KRH93199.1 - 0.019 14.7 0.0 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DNA_pol3_theta PF06440.6 KRH93199.1 - 0.066 12.8 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, theta subunit RAMPs PF03787.10 KRH93199.1 - 0.08 12.7 4.2 0.046 13.5 0.5 2.0 1 1 1 2 2 2 0 RAMP superfamily AMP-binding PF00501.23 KRH93200.1 - 1.4e-72 244.3 0.0 2e-54 184.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme zf-rbx1 PF12678.2 KRH93201.1 - 1.8e-26 92.0 12.9 2.1e-26 91.8 9.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KRH93201.1 - 5.1e-17 61.5 9.3 6e-17 61.2 6.4 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KRH93201.1 - 9.8e-08 31.7 13.2 9e-07 28.6 9.2 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KRH93201.1 - 8.2e-05 22.1 14.1 0.0028 17.2 9.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH93201.1 - 0.00094 18.8 11.2 0.15 11.7 7.8 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH93201.1 - 0.0014 18.2 9.5 0.017 14.8 4.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KRH93201.1 - 0.0052 16.7 13.3 0.13 12.2 9.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TBCC PF07986.7 KRH93201.1 - 0.0054 16.1 2.8 0.0068 15.8 1.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor C FANCL_C PF11793.3 KRH93201.1 - 0.011 15.6 12.1 0.022 14.7 8.4 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 KRH93201.1 - 0.057 13.2 4.7 0.066 13.0 3.2 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain HTH_Tnp_Tc3_1 PF11427.3 KRH93201.1 - 0.058 13.0 0.2 0.34 10.5 0.1 2.1 1 1 1 2 2 2 0 Tc3 transposase zf-HC5HC2H_2 PF13832.1 KRH93201.1 - 0.2 11.6 12.0 0.36 10.8 8.3 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 KRH93201.1 - 0.23 11.0 6.3 0.48 9.9 4.4 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 KRH93201.1 - 0.32 11.1 12.5 3.1 7.9 8.7 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 KRH93201.1 - 0.86 9.3 9.9 1.5 8.5 6.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KRH93201.1 - 2.6 8.1 12.7 14 5.7 8.8 2.0 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 KRH93201.1 - 6.3 6.7 9.3 1.3 8.9 0.4 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KRH93201.1 - 9.3 6.0 9.7 47 3.8 6.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.27 KRH93202.1 - 1.1e-24 85.3 0.0 1.3e-05 24.8 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat DNA_pol_A_exo1 PF01612.15 KRH93204.1 - 0.014 14.9 1.5 0.026 14.0 0.7 1.8 1 1 1 2 2 2 0 3'-5' exonuclease Sugar_tr PF00083.19 KRH93205.1 - 2.2e-18 66.0 11.3 2.7e-18 65.7 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2749 PF10907.3 KRH93205.1 - 0.023 14.5 0.4 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Dsl1_C PF11989.3 KRH93207.1 - 0.087 11.9 4.5 0.11 11.6 3.1 1.0 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal BRCT PF00533.21 KRH93207.1 - 0.093 12.8 0.8 1.5 9.0 0.0 2.2 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KRH93208.1 - 1e-47 161.6 1.1 2e-40 138.0 0.0 3.6 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KRH93208.1 - 1.1e-09 38.5 0.0 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.12 KRH93208.1 - 3.4e-08 33.1 0.0 0.0017 17.7 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 KRH93208.1 - 2.4e-07 30.5 0.1 0.00022 20.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KRH93208.1 - 2.7e-07 30.7 4.0 0.0014 18.7 1.4 3.6 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KRH93208.1 - 1e-06 28.4 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 2 Part of AAA domain ABC_tran PF00005.22 KRH93208.1 - 1.4e-06 28.6 0.2 0.0018 18.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.9 KRH93208.1 - 1.8e-06 27.9 0.4 2.6e-05 24.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) DEAD PF00270.24 KRH93208.1 - 2.9e-06 26.8 0.0 0.18 11.2 0.0 3.5 2 2 1 3 3 3 2 DEAD/DEAH box helicase DUF2075 PF09848.4 KRH93208.1 - 2.9e-06 26.4 0.1 0.024 13.6 0.0 3.2 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 KRH93208.1 - 1.3e-05 24.0 0.0 0.021 13.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KRH93208.1 - 3.1e-05 24.0 0.4 0.045 13.9 0.0 4.0 4 1 0 4 4 3 1 RNA helicase Sigma54_activat PF00158.21 KRH93208.1 - 4.8e-05 22.8 0.0 0.15 11.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 KRH93208.1 - 6.3e-05 22.2 1.8 0.061 12.4 0.0 3.3 3 1 0 4 4 3 2 KaiC Mg_chelatase PF01078.16 KRH93208.1 - 6.5e-05 22.1 0.0 0.0044 16.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KRH93208.1 - 8e-05 23.4 0.3 0.00072 20.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 KRH93208.1 - 8.3e-05 21.9 0.0 0.25 10.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.1 KRH93208.1 - 0.00011 21.7 0.1 0.57 9.5 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KRH93208.1 - 0.00011 22.1 9.9 0.0058 16.5 0.1 4.2 3 1 1 4 4 4 1 AAA domain AAA_18 PF13238.1 KRH93208.1 - 0.00033 20.9 4.1 0.00099 19.4 0.2 3.2 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.1 KRH93208.1 - 0.0017 18.0 2.7 0.25 10.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KRH93208.1 - 0.0018 17.9 0.3 1.4 8.5 0.1 2.9 2 1 0 2 2 2 1 NACHT domain RuvB_N PF05496.7 KRH93208.1 - 0.002 17.2 0.2 0.025 13.6 0.2 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KRH93208.1 - 0.0025 17.7 0.0 0.035 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KRH93208.1 - 0.0028 16.6 0.1 0.03 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KRH93208.1 - 0.0028 17.3 11.3 0.099 12.3 0.5 4.4 4 1 0 4 4 4 2 Archaeal ATPase AAA_3 PF07726.6 KRH93208.1 - 0.0045 16.5 0.1 0.02 14.4 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KRH93208.1 - 0.0084 16.5 0.0 5.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Zot PF05707.7 KRH93208.1 - 0.015 14.7 0.1 0.79 9.1 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.1 KRH93208.1 - 0.015 14.8 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KRH93208.1 - 0.019 13.8 0.0 0.62 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 KRH93208.1 - 0.023 13.6 0.1 6.2 5.6 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_28 PF13521.1 KRH93208.1 - 0.027 14.4 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KRH93208.1 - 0.032 13.4 2.4 0.038 13.1 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 CDC48_N PF02359.13 KRH93208.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain UPF0079 PF02367.12 KRH93208.1 - 0.044 13.4 0.0 0.98 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 KRH93208.1 - 0.045 13.5 6.3 2.6 7.8 0.0 3.3 4 1 0 4 4 2 0 Type III restriction enzyme, res subunit T4_baseplate PF12322.3 KRH93210.1 - 0.0021 17.3 0.0 0.0021 17.3 0.0 1.0 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.14 KRH93210.1 - 0.0025 17.2 0.3 0.004 16.6 0.2 1.3 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.1 KRH93210.1 - 0.034 13.3 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KRH93210.1 - 0.044 13.7 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 KRH93210.1 - 0.052 13.2 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Vps39_2 PF10367.4 KRH93210.1 - 0.066 13.3 0.0 0.08 13.1 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Ribosomal_S27e PF01667.12 KRH93210.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 Methyltransf_6 PF03737.10 KRH93210.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Demethylmenaquinone methyltransferase DDE_Tnp_IS1595 PF12762.2 KRH93211.1 - 1.1e-09 38.3 0.0 1.3e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain N_Asn_amidohyd PF14736.1 KRH93213.1 - 0.032 13.0 0.1 0.036 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase zf-CHY PF05495.7 KRH93213.1 - 0.24 11.6 6.0 2.5 8.3 2.8 2.3 2 0 0 2 2 2 0 CHY zinc finger DZR PF12773.2 KRH93213.1 - 0.38 10.6 8.2 2.6 7.9 5.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KRH93213.1 - 0.75 9.3 5.6 0.6 9.6 2.3 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 FYDLN_acid PF09538.5 KRH93213.1 - 0.96 10.0 4.2 2 9.0 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_3 PF13920.1 KRH93213.1 - 1.1 9.0 6.8 4.6 6.9 2.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBP PF02148.14 KRH93213.1 - 1.4 9.1 6.6 0.42 10.7 0.5 2.5 1 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 KRH93213.1 - 2 8.2 7.4 2 8.2 4.0 2.0 1 1 0 1 1 1 0 BED zinc finger HypA PF01155.14 KRH93213.1 - 2 8.1 4.8 4.3 7.0 3.3 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 KRH93213.1 - 5.3 7.5 9.9 2.8 8.4 1.6 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-rbx1 PF12678.2 KRH93214.1 - 1.9e-21 75.9 16.3 2.2e-21 75.7 11.3 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KRH93214.1 - 4.6e-19 68.0 14.6 5.6e-19 67.7 10.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KRH93214.1 - 8.6e-08 31.8 16.6 8.6e-08 31.8 11.5 2.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KRH93214.1 - 7.2e-05 22.3 19.2 0.00017 21.1 11.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH93214.1 - 0.00014 21.4 20.4 0.00015 21.3 9.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH93214.1 - 0.002 18.1 19.1 0.019 15.0 11.7 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH93214.1 - 0.002 17.8 11.4 0.002 17.8 7.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KRH93214.1 - 0.015 15.0 2.5 0.015 15.0 1.7 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KRH93214.1 - 0.18 11.3 9.2 0.27 10.7 6.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 KRH93214.1 - 0.27 11.0 14.3 0.4 10.5 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon XPA_N PF01286.13 KRH93214.1 - 1.5 8.5 6.2 8.9 6.0 0.2 3.3 2 1 1 3 3 3 0 XPA protein N-terminal FANCL_C PF11793.3 KRH93214.1 - 2 8.4 16.1 0.88 9.5 7.4 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.9 KRH93214.1 - 2.3 7.7 15.7 6.6 6.2 7.3 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 KRH93214.1 - 3.1 7.4 19.9 5.9 6.5 9.2 2.8 1 1 1 2 2 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KRH93214.1 - 5.6 7.0 15.4 12 5.9 10.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-CHY PF05495.7 KRH93214.1 - 6.6 6.9 15.8 15 5.8 6.6 2.2 1 1 1 2 2 2 0 CHY zinc finger DUF2256 PF10013.4 KRH93214.1 - 7.5 6.3 14.1 3.7 7.3 1.2 3.8 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Baculo_RING PF05883.6 KRH93214.1 - 8.1 6.2 9.7 18 5.1 6.7 1.6 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-HC5HC2H PF13771.1 KRH93214.1 - 8.5 6.5 17.0 36 4.5 11.9 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain Ferritin PF00210.19 KRH93215.1 - 5.1e-26 91.1 3.2 6.3e-26 90.8 2.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain ERCC4 PF02732.10 KRH93215.1 - 0.012 15.3 0.1 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 ERCC4 domain MA3 PF02847.12 KRH93215.1 - 0.061 13.0 0.9 0.11 12.2 0.7 1.4 1 0 0 1 1 1 0 MA3 domain TB2_DP1_HVA22 PF03134.14 KRH93216.1 - 3.9e-10 39.3 7.3 6.3e-10 38.6 5.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family EzrA PF06160.7 KRH93216.1 - 0.0026 15.9 1.3 0.0034 15.6 0.9 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF3810 PF12725.2 KRH93216.1 - 0.06 12.2 0.7 0.075 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF837 PF05769.6 KRH93216.1 - 0.1 12.1 1.5 0.13 11.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Peptidase_A3 PF02160.10 KRH93216.1 - 3.4 7.2 9.2 0.23 11.0 2.0 1.9 1 1 1 2 2 2 0 Cauliflower mosaic virus peptidase (A3) N6_N4_Mtase PF01555.13 KRH93217.1 - 0.56 9.6 4.4 0.8 9.1 3.1 1.2 1 0 0 1 1 1 0 DNA methylase OmpH PF03938.9 KRH93217.1 - 1 9.2 5.8 0.45 10.4 1.5 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 KRH93218.1 - 0.012 15.4 4.4 0.064 13.1 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1283 PF06932.6 KRH93219.1 - 0.024 14.6 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) FeThRed_A PF02941.10 KRH93219.1 - 0.12 12.3 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase variable alpha chain SNF2_N PF00176.18 KRH93220.1 - 4.2e-44 150.5 0.2 9.3e-44 149.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DASH_Dad1 PF08649.5 KRH93220.1 - 2.9 7.6 8.6 4.8 6.9 0.0 4.6 4 1 0 4 4 4 0 DASH complex subunit Dad1 DEAD PF00270.24 KRH93221.1 - 6.2e-19 68.1 0.6 5.1e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93221.1 - 2.5e-08 33.6 0.2 7e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 KRH93221.1 - 1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 KRH93221.1 - 0.00097 18.2 1.2 0.00098 18.1 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SecA_DEAD PF07517.9 KRH93221.1 - 0.0067 15.7 0.6 3.1 7.0 0.0 2.7 1 1 0 3 3 3 2 SecA DEAD-like domain CmcH_NodU PF02543.10 KRH93221.1 - 0.034 13.2 0.4 0.034 13.2 0.2 2.2 1 1 1 2 2 2 0 Carbamoyltransferase Helicase_RecD PF05127.9 KRH93221.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Helicase GerE PF00196.14 KRH93221.1 - 0.27 10.5 3.8 18 4.7 0.1 3.6 3 1 0 3 3 3 0 Bacterial regulatory proteins, luxR family PhnA_Zn_Ribbon PF08274.7 KRH93223.1 - 0.086 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Prim_Zn_Ribbon PF08273.7 KRH93223.1 - 0.12 12.4 0.8 0.19 11.8 0.6 1.5 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase DDE_Tnp_IS1595 PF12762.2 KRH93224.1 - 4.9e-28 97.8 0.1 5.6e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3936 PF13072.1 KRH93224.1 - 0.071 12.5 2.3 0.29 10.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Striatin PF08232.7 KRH93224.1 - 0.091 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Striatin family tRNA_bind PF01588.15 KRH93227.1 - 1.7e-22 79.0 0.0 3.1e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 KRH93227.1 - 0.0086 16.0 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KRH93227.1 - 0.081 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Slx4 PF09494.5 KRH93228.1 - 0.03 14.0 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Slx4 endonuclease Beta-Casp PF10996.3 KRH93228.1 - 0.033 14.1 0.1 0.044 13.7 0.0 1.4 1 1 0 1 1 1 0 Beta-Casp domain Retrotrans_gag PF03732.12 KRH93228.1 - 0.093 12.8 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein NifT PF06988.6 KRH93230.1 - 0.0083 15.5 0.0 0.021 14.2 0.0 1.8 1 0 0 1 1 1 1 NifT/FixU protein Utp14 PF04615.8 KRH93231.1 - 7.6e-23 80.6 29.8 2.3e-21 75.7 4.7 2.9 1 1 2 3 3 3 2 Utp14 protein Ead_Ea22 PF13935.1 KRH93231.1 - 0.3 11.4 8.4 0.37 11.1 5.0 1.7 1 1 0 1 1 1 0 Ead/Ea22-like protein TFIID_30kDa PF03540.8 KRH93232.1 - 6.6e-15 54.6 0.1 1.4e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit HeH PF12949.2 KRH93232.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Bromo_TP PF07524.8 KRH93232.1 - 0.061 13.0 0.1 7.7 6.3 0.0 2.2 1 1 1 2 2 2 0 Bromodomain associated TAF PF02969.12 KRH93232.1 - 0.091 12.7 1.3 0.79 9.7 0.9 2.2 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Iron_traffic PF04362.9 KRH93232.1 - 0.11 11.9 0.2 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking DUF4316 PF14195.1 KRH93232.1 - 0.73 9.9 4.0 1.2 9.2 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) Acyltransferase PF01553.16 KRH93233.1 - 6.1e-13 48.3 0.4 1.5e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 Acyltransferase Ricin_B_lectin PF00652.17 KRH93234.1 - 0.0039 17.2 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KRH93234.1 - 0.04 14.2 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like HAD PF12710.2 KRH93238.1 - 1.9e-22 80.3 0.1 3.9e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KRH93238.1 - 8.1e-21 74.1 4.5 1.9e-19 69.6 3.1 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KRH93238.1 - 2e-20 74.1 0.0 3.7e-13 50.3 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KRH93238.1 - 6.7e-07 29.1 0.1 2.9e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KRH93238.1 - 0.01 15.4 8.1 0.42 10.1 0.1 3.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase PTR2 PF00854.16 KRH93239.1 - 1.7e-12 46.8 7.7 2.9e-08 32.8 1.9 2.2 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 KRH93239.1 - 0.048 12.3 16.4 0.053 12.2 9.9 1.7 1 1 1 2 2 2 0 Major Facilitator Superfamily RseC_MucC PF04246.7 KRH93239.1 - 1.7 8.2 7.0 4.9 6.7 0.6 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NfeD PF01957.13 KRH93239.1 - 2.7 8.1 8.8 0.66 10.1 1.0 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Sec66 PF09802.4 KRH93240.1 - 0.007 15.7 7.0 0.021 14.2 4.9 1.8 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3492 PF11997.3 KRH93240.1 - 0.086 12.3 1.1 0.53 9.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Peptidase_M16 PF00675.15 KRH93240.1 - 0.22 11.2 1.8 0.56 9.9 0.6 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) THOC7 PF05615.8 KRH93241.1 - 0.0017 18.6 2.7 0.002 18.4 1.9 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 DUF465 PF04325.8 KRH93241.1 - 0.1 12.3 3.5 0.25 11.0 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF465) DUF1444 PF07285.6 KRH93241.1 - 0.1 11.8 1.7 0.098 11.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) YvrJ PF12841.2 KRH93241.1 - 0.1 11.8 1.7 1.5 8.1 0.1 2.4 2 0 0 2 2 2 0 YvrJ protein family BLOC1_2 PF10046.4 KRH93241.1 - 0.14 12.3 6.3 0.17 12.0 4.4 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 KRH93241.1 - 0.18 11.7 2.5 0.32 10.9 1.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Blo-t-5 PF11642.3 KRH93241.1 - 0.25 11.1 3.3 0.37 10.5 2.3 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 Spc7 PF08317.6 KRH93241.1 - 0.31 9.6 6.0 0.36 9.4 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KRH93241.1 - 0.5 10.2 11.1 0.028 14.2 3.9 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.6 KRH93241.1 - 0.87 9.4 4.2 0.56 10.0 0.9 1.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF724 PF05266.9 KRH93241.1 - 1.1 8.8 5.0 1.5 8.3 3.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tropomyosin_1 PF12718.2 KRH93241.1 - 1.1 9.1 5.9 0.8 9.5 2.0 1.8 1 1 0 1 1 1 0 Tropomyosin like DivIC PF04977.10 KRH93241.1 - 1.8 8.1 4.8 12 5.5 3.1 2.1 1 1 0 1 1 1 0 Septum formation initiator Nup160 PF11715.3 KRH93242.1 - 0.033 12.3 0.0 0.046 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 KRH93242.1 - 0.081 12.8 0.2 0.41 10.6 0.0 2.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Glutaredoxin PF00462.19 KRH93243.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KRH93243.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4108 PF13390.1 KRH93244.1 - 0.02 14.6 8.0 0.028 14.1 0.6 3.5 1 1 1 4 4 4 0 Protein of unknown function (DUF4108) KH_1 PF00013.24 KRH93245.1 - 2.5e-06 27.0 0.2 4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KRH93245.1 - 3.7e-06 26.4 0.3 6.5e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 KRH93245.1 - 0.01 15.3 0.3 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 KH domain PepSY_TM_1 PF13172.1 KRH93246.1 - 0.014 15.1 0.3 0.014 15.1 0.2 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix PepSY_TM_3 PF13706.1 KRH93246.1 - 0.017 14.5 0.8 0.056 12.8 0.5 2.0 1 0 0 1 1 1 0 PepSY-associated TM helix DUF788 PF05620.6 KRH93246.1 - 0.69 9.7 4.6 6.4 6.5 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) WD40 PF00400.27 KRH93247.1 - 8.6e-38 126.8 3.1 7.8e-12 44.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KRH93247.1 - 1.1e-25 90.4 19.6 1.1e-25 90.4 13.6 1.8 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 KRH93247.1 - 0.00035 18.8 2.5 0.23 9.5 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 RecR PF02132.10 KRH93247.1 - 0.14 11.6 2.4 0.32 10.4 1.6 1.5 1 0 0 1 1 1 0 RecR protein DDE_3 PF13358.1 KRH93248.1 - 2.8e-08 33.6 0.1 3.5e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ACI44 PF15270.1 KRH93249.1 - 0.02 14.8 1.6 0.076 13.0 1.1 2.0 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor Peptidase_M1 PF01433.15 KRH93250.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 DUF4399 PF14347.1 KRH93250.1 - 0.07 13.1 0.1 4.4 7.4 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4399) DUF3563 PF12086.3 KRH93250.1 - 0.097 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Peptidase_M1 PF01433.15 KRH93251.1 - 1.1e-56 192.6 0.7 2.7e-52 178.1 0.8 2.3 1 1 1 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 KRH93251.1 - 8.2e-17 61.4 0.0 2.8e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase MA superfamily MgtE PF01769.11 KRH93255.1 - 0.00011 22.4 4.8 0.00011 22.4 3.3 5.3 4 2 1 6 6 6 2 Divalent cation transporter Nodulin_late PF07127.6 KRH93255.1 - 4.2 7.5 6.9 7.1 6.8 0.6 3.2 1 1 1 2 2 2 0 Late nodulin protein TMEM18 PF14770.1 KRH93256.1 - 0.11 12.0 0.1 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 18 DUF1699 PF08004.6 KRH93257.1 - 0.022 14.2 0.3 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) UCH PF00443.24 KRH93260.1 - 1.5e-06 27.5 1.2 2.8e-06 26.6 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KRH93260.1 - 0.0033 16.9 0.4 0.0079 15.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM_X2 PF03442.9 KRH93261.1 - 0.037 13.8 0.2 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 DUF2490 PF10677.4 KRH93261.1 - 0.075 12.2 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) DUF3596 PF12167.3 KRH93261.1 - 0.14 11.6 1.3 0.28 10.7 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Glyco_hydro_19 PF00182.14 KRH93262.1 - 2.1e-25 89.7 0.1 6.3e-24 84.9 0.1 2.5 1 1 0 1 1 1 1 Chitinase class I Zn_ribbon_recom PF13408.1 KRH93263.1 - 0.0021 18.2 1.8 0.0026 18.0 1.2 1.2 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 KRH93263.1 - 0.018 14.4 0.2 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DDE_3 PF13358.1 KRH93264.1 - 8.9e-29 100.1 0.0 1.1e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 KRH93264.1 - 0.0029 16.7 0.1 0.0037 16.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sec63 PF02889.11 KRH93266.1 - 1.5e-12 47.3 6.3 1.4e-10 40.9 4.2 2.5 1 1 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KRH93266.1 - 7.6e-11 41.7 0.1 5.4e-07 29.2 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93266.1 - 1.2e-07 31.5 0.0 4e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dynamin_M PF01031.15 KRH93267.1 - 5.6e-65 219.0 1.7 5.6e-65 219.0 1.2 2.0 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 KRH93267.1 - 2.8e-45 154.1 2.6 2.8e-45 154.1 1.8 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KRH93267.1 - 1.5e-19 69.7 2.9 2.5e-19 68.9 0.8 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KRH93267.1 - 0.00033 20.6 6.2 0.0015 18.4 4.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KRH93267.1 - 0.0037 17.7 0.1 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Peptidase_S49_N PF08496.5 KRH93269.1 - 0.039 13.7 1.1 0.16 11.7 0.8 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Octopine_DH PF02317.12 KRH93270.1 - 0.017 14.7 0.0 0.017 14.7 0.0 1.0 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF4446 PF14584.1 KRH93270.1 - 0.069 12.9 0.8 0.068 12.9 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3165 PF11364.3 KRH93270.1 - 0.09 12.9 2.3 0.095 12.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) GCS PF03074.11 KRH93272.1 - 9.1e-68 228.9 14.3 9.4e-67 225.6 9.9 2.3 1 1 0 1 1 1 1 Glutamate-cysteine ligase DUF2769 PF10967.3 KRH93272.1 - 0.038 14.2 0.3 0.096 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) Ndr PF03096.9 KRH93272.1 - 0.039 12.4 2.6 0.42 9.0 0.1 2.9 2 1 1 3 3 3 0 Ndr family Sugar_tr PF00083.19 KRH93273.1 - 3.2e-30 105.1 35.4 1.6e-22 79.7 6.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KRH93273.1 - 9e-18 64.0 27.8 2.8e-17 62.4 5.7 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Fibrillarin PF01269.12 KRH93274.1 - 2.7e-108 360.2 0.0 3.1e-108 359.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KRH93274.1 - 0.0043 16.5 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KRH93274.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4233 PF14017.1 KRH93276.1 - 0.36 10.7 7.3 1.4 8.8 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4233) Cpn60_TCP1 PF00118.19 KRH93277.1 - 1.6e-120 402.9 14.8 1.8e-120 402.8 10.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3155 PF11352.3 KRH93277.1 - 0.091 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) DUF2624 PF11116.3 KRH93277.1 - 0.12 12.9 1.5 0.85 10.1 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2624) Sigma_reg_N PF13800.1 KRH93278.1 - 0.00013 21.9 3.3 0.0014 18.5 0.0 2.7 2 1 0 2 2 2 1 Sigma factor regulator N-terminal DUF95 PF01944.12 KRH93278.1 - 0.00028 20.5 0.0 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 Integral membrane protein DUF95 Otopetrin PF03189.8 KRH93278.1 - 0.00028 20.0 1.3 0.00039 19.5 0.9 1.1 1 0 0 1 1 1 1 Otopetrin DUF1700 PF08006.6 KRH93278.1 - 0.0076 15.5 0.2 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) DDHD PF02862.12 KRH93278.1 - 0.035 13.9 1.3 0.041 13.6 0.9 1.2 1 0 0 1 1 1 0 DDHD domain ETRAMP PF09716.5 KRH93278.1 - 0.04 13.8 0.1 0.98 9.4 0.0 2.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RP-C_C PF11800.3 KRH93278.1 - 0.095 12.3 0.5 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4337 PF14235.1 KRH93278.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Shisa PF13908.1 KRH93278.1 - 0.29 11.2 1.5 0.39 10.8 0.2 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Vpu PF00558.14 KRH93278.1 - 1.1 8.9 5.5 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Vpu protein ABC2_membrane_3 PF12698.2 KRH93278.1 - 1.1 8.2 11.9 3.9 6.4 8.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF912 PF06024.7 KRH93278.1 - 3.9 7.5 11.7 0.42 10.6 4.3 2.3 2 1 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) gag-asp_proteas PF13975.1 KRH93280.1 - 6.5e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KRH93280.1 - 0.0017 18.8 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 KRH93280.1 - 0.0064 16.5 0.2 2.9 8.0 0.0 2.8 1 1 1 2 2 2 2 Retrotransposon gag protein eIF3g PF12353.3 KRH93280.1 - 0.007 16.2 1.6 0.018 14.9 1.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RVP PF00077.15 KRH93280.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF793 PF05633.6 KRH93280.1 - 0.058 12.1 0.9 0.21 10.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF793) Pex16 PF08610.5 KRH93280.1 - 0.064 12.2 1.0 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RVT_1 PF00078.22 KRH93282.1 - 9.3e-23 80.7 0.6 2.1e-22 79.5 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93282.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FNIP PF05725.7 KRH93283.1 - 0.14 12.1 0.8 0.22 11.4 0.5 1.6 1 1 0 1 1 1 0 FNIP Repeat HTH_29 PF13551.1 KRH93284.1 - 0.00017 21.7 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KRH93284.1 - 0.0005 20.8 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.13 KRH93284.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.13 KRH93284.1 - 0.011 15.7 0.0 0.085 12.9 0.0 2.4 1 1 1 2 2 2 0 Transposase RNA_pol_Rpb4 PF03874.11 KRH93284.1 - 0.049 13.6 0.3 0.067 13.2 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 DDE_3 PF13358.1 KRH93284.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 KRH93285.1 - 2.1e-22 79.5 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Smac_DIABLO PF09057.5 KRH93286.1 - 0.0079 15.3 0.3 0.011 14.8 0.2 1.2 1 0 0 1 1 1 1 Second Mitochondria-derived Activator of Caspases PTR PF12789.2 KRH93286.1 - 0.044 13.6 1.2 0.11 12.3 0.8 1.7 1 0 0 1 1 1 0 Phage tail repeat like Mannitol_dh_C PF08125.8 KRH93286.1 - 0.12 11.5 1.9 0.099 11.8 0.5 1.5 1 1 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain TFCD_C PF12612.3 KRH93286.1 - 0.16 11.3 4.6 0.079 12.3 1.2 2.0 1 1 1 2 2 2 0 Tubulin folding cofactor D C terminal DUF445 PF04286.7 KRH93286.1 - 0.26 10.7 5.1 0.34 10.3 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SecA_DEAD PF07517.9 KRH93288.1 - 0.12 11.6 0.2 0.19 11.0 0.1 1.4 1 1 0 1 1 1 0 SecA DEAD-like domain RVT_1 PF00078.22 KRH93289.1 - 1e-21 77.3 0.8 2.3e-21 76.1 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH93289.1 - 0.00028 20.7 0.3 0.00028 20.7 0.2 2.8 2 1 1 3 3 3 1 Retroviral aspartyl protease RVT_thumb PF06817.9 KRH93289.1 - 0.0003 20.3 0.8 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase thumb domain Asp_protease_2 PF13650.1 KRH93289.1 - 0.0048 17.3 0.0 0.025 15.0 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease Med3 PF11593.3 KRH93290.1 - 1.4 8.1 10.4 1.3 8.1 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PRP3 PF08572.5 KRH93291.1 - 3.9 6.7 16.6 0.95 8.7 8.4 2.0 2 1 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Proteasome PF00227.21 KRH93292.1 - 1.5e-18 66.7 0.0 4.9e-17 61.8 0.0 2.2 1 1 0 1 1 1 1 Proteasome subunit Brix PF04427.13 KRH93293.1 - 1.2e-06 28.3 0.5 1.7e-06 27.8 0.4 1.3 1 0 0 1 1 1 1 Brix domain RVP_2 PF08284.6 KRH93295.1 - 8.6e-05 22.4 0.1 0.00011 22.2 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH93295.1 - 0.0001 22.1 0.1 0.00018 21.3 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93295.1 - 0.00031 20.3 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KRH93295.1 - 0.0009 19.7 0.1 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease P34-Arc PF04045.9 KRH93295.1 - 0.097 11.9 0.5 0.11 11.7 0.3 1.1 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc gag-asp_proteas PF13975.1 KRH93295.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Rad51 PF08423.6 KRH93297.1 - 7.3e-138 457.6 0.1 2.1e-137 456.1 0.0 1.7 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 KRH93297.1 - 7.1e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KRH93297.1 - 6.2e-10 39.1 0.8 1.7e-09 37.6 0.5 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 KRH93297.1 - 4e-07 29.4 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KRH93297.1 - 1.9e-06 27.1 0.0 2.9e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 KRH93297.1 - 0.0024 17.9 0.0 0.0063 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.10 KRH93297.1 - 0.13 11.6 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF2115 PF09888.4 KRH93298.1 - 0.11 12.5 1.6 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) KH_1 PF00013.24 KRH93299.1 - 5.3e-07 29.1 1.3 1.2e-06 28.0 0.9 1.6 1 0 0 1 1 1 1 KH domain Egg_lysin PF01303.12 KRH93299.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) DUF3689 PF12463.3 KRH93302.1 - 0.041 12.6 0.1 0.041 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) DegQ PF08181.6 KRH93303.1 - 0.031 13.9 1.9 6.3 6.6 0.4 2.5 2 0 0 2 2 2 0 DegQ (SacQ) family Flocculin PF00624.13 KRH93303.1 - 0.04 13.7 0.3 0.09 12.6 0.2 1.6 1 0 0 1 1 1 0 Flocculin repeat DUF2142 PF09913.4 KRH93303.1 - 4.6 5.7 14.3 0.8 8.2 4.7 2.5 1 1 2 3 3 3 0 Predicted membrane protein (DUF2142) DUF368 PF04018.8 KRH93303.1 - 6.6 5.8 13.1 0.56 9.3 3.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF368) DUF962 PF06127.6 KRH93303.1 - 9.4 6.2 7.7 2.6 8.0 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) CBFD_NFYB_HMF PF00808.18 KRH93304.1 - 5.4e-06 26.3 0.8 2.6e-05 24.1 0.6 2.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIN_2 PF10130.4 KRH93304.1 - 0.91 9.5 4.3 1 9.4 2.3 1.5 1 1 0 1 1 1 0 PIN domain Acetyltransf_1 PF00583.19 KRH93305.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KRH93305.1 - 2.3e-06 27.6 0.0 1.8e-05 24.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KRH93305.1 - 4.1e-05 23.2 0.0 7.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KRH93305.1 - 0.00032 20.8 0.1 0.00066 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KRH93305.1 - 0.044 13.9 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Clenterotox PF03505.9 KRH93305.1 - 0.054 12.8 3.3 0.11 11.8 1.5 2.0 2 1 0 2 2 2 0 Clostridium enterotoxin Acetyltransf_9 PF13527.1 KRH93305.1 - 0.15 11.8 0.0 0.73 9.6 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Methyltransf_32 PF13679.1 KRH93307.1 - 0.003 17.2 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF4546 PF15079.1 KRH93307.1 - 0.089 11.9 0.1 0.11 11.6 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4546) tRNA-synt_2 PF00152.15 KRH93309.1 - 2.5e-17 62.6 0.0 2.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KRH93309.1 - 0.011 14.9 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DDE_Tnp_IS1595 PF12762.2 KRH93311.1 - 2.5e-21 76.0 0.1 2.1e-20 73.0 0.0 2.2 2 0 0 2 2 2 1 ISXO2-like transposase domain DNA_ligase_ZBD PF03119.11 KRH93311.1 - 0.0021 17.7 0.3 0.0048 16.5 0.2 1.6 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.14 KRH93311.1 - 0.0046 16.4 0.2 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger DDE_Tnp_IS66 PF03050.9 KRH93311.1 - 0.0054 15.9 0.0 0.0071 15.5 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family T4_baseplate PF12322.3 KRH93311.1 - 0.05 12.8 0.2 0.069 12.3 0.2 1.4 1 1 0 1 1 1 0 T4 bacteriophage base plate protein Zn-ribbon_8 PF09723.5 KRH93311.1 - 0.13 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain RVT_1 PF00078.22 KRH93312.1 - 5.7e-07 29.0 0.1 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C_2 PF13307.1 KRH93314.1 - 2.2e-33 115.5 0.0 4.3e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain Helicase_C_2 PF13307.1 KRH93316.1 - 1.4e-33 116.2 0.0 2.5e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DIPSY PF11763.3 KRH93317.1 - 0.069 12.9 1.2 0.24 11.2 0.8 1.9 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Acetyltransf_1 PF00583.19 KRH93318.1 - 3.8e-17 62.0 0.1 5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KRH93318.1 - 1.1e-10 41.5 0.1 1.5e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KRH93318.1 - 1.9e-06 27.7 0.0 2.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KRH93318.1 - 4.8e-06 26.6 0.0 5.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KRH93318.1 - 9.4e-06 25.3 0.0 3.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KRH93318.1 - 0.0009 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KRH93318.1 - 0.0023 18.1 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KRH93318.1 - 0.0032 17.4 0.1 0.0055 16.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Imm23 PF15593.1 KRH93318.1 - 0.048 13.8 0.1 0.064 13.4 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 23 DUF3749 PF12568.3 KRH93318.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RVP PF00077.15 KRH93320.1 - 2.5e-06 27.3 0.2 4.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Pkinase PF00069.20 KRH93321.1 - 3e-61 206.8 0.1 3e-61 206.8 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93321.1 - 1.2e-36 126.1 0.4 5.2e-36 124.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.17 KRH93321.1 - 2.2e-09 36.8 21.6 4.9e-05 22.9 4.5 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KRH93321.1 - 9.1e-08 31.3 0.0 1.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like HC2 PF07382.6 KRH93321.1 - 5.1 6.9 14.7 2 8.2 7.5 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 HATPase_c_3 PF13589.1 KRH93322.1 - 1.5e-12 47.3 0.3 4.2e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KRH93322.1 - 3e-08 33.3 0.2 8.2e-08 31.9 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acetyltransf_1 PF00583.19 KRH93324.1 - 2.3e-11 43.5 0.0 3.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KRH93324.1 - 0.0035 17.2 1.8 0.0053 16.7 1.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KRH93324.1 - 0.0093 16.1 0.2 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KRH93324.1 - 0.041 13.9 0.0 0.06 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KRH93324.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 KRH93324.1 - 0.066 13.0 0.1 0.091 12.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.26 KRH93325.1 - 7.4e-14 51.5 0.3 0.0012 18.9 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KRH93325.1 - 0.0011 19.0 9.0 0.87 9.7 0.1 4.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Proteasome PF00227.21 KRH93326.1 - 1.1e-24 86.7 0.2 2.8e-24 85.4 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 KRH93326.1 - 2.2e-07 30.0 0.0 4.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature COG5 PF10392.4 KRH93327.1 - 0.0044 16.9 2.4 0.0044 16.9 1.6 1.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Phage_GP20 PF06810.6 KRH93327.1 - 0.028 13.8 1.3 0.028 13.8 0.9 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 RE_HindIII PF09518.5 KRH93327.1 - 0.056 12.3 1.1 0.054 12.3 0.8 1.0 1 0 0 1 1 1 0 HindIII restriction endonuclease Pox_polyA_pol_N PF12630.2 KRH93327.1 - 0.24 11.5 2.9 0.27 11.3 2.0 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Sas10 PF09368.5 KRH93327.1 - 0.48 10.6 4.2 0.63 10.2 2.9 1.3 1 1 0 1 1 1 0 Sas10 C-terminal domain DUF2361 PF10153.4 KRH93327.1 - 0.64 10.2 6.4 0.68 10.1 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) SAB PF04382.8 KRH93327.1 - 4.3 7.1 8.3 1.5 8.5 1.5 2.2 1 1 1 2 2 2 0 SAB domain KMP11 PF03037.11 KRH93327.1 - 8.3 7.0 8.6 9.7 6.8 5.9 1.2 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 ubiquitin PF00240.18 KRH93328.1 - 5.9e-35 118.5 1.5 1.8e-34 116.9 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KRH93328.1 - 4.9e-20 70.9 0.3 8.1e-20 70.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 KRH93328.1 - 8.5e-12 44.6 2.4 1.4e-11 43.9 1.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 KRH93328.1 - 6.5e-06 26.3 0.2 6.5e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KRH93328.1 - 0.00035 20.4 0.1 0.00079 19.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 KRH93328.1 - 0.00039 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KRH93328.1 - 0.031 14.4 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain tRNA-synt_2c PF01411.14 KRH93328.1 - 0.047 11.9 0.0 0.047 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) DZR PF12773.2 KRH93328.1 - 0.081 12.7 0.4 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon Plexin_cytopl PF08337.7 KRH93328.1 - 0.09 11.0 0.5 0.86 7.8 0.0 1.9 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 KRH93328.1 - 0.093 12.4 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain CARD PF00619.16 KRH93329.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Caspase recruitment domain Sec23_trunk PF04811.10 KRH93331.1 - 1.7e-34 119.2 0.1 2.5e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KRH93331.1 - 1.6e-12 46.7 1.4 2.8e-12 45.9 0.2 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KRH93331.1 - 1.4e-09 37.3 5.6 2.9e-09 36.3 3.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KRH93331.1 - 4.2e-09 36.7 0.0 8.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KRH93331.1 - 5.5e-06 25.9 0.0 1.6e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF2296 PF10058.4 KRH93331.1 - 0.02 14.6 2.6 0.045 13.5 1.8 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ribosomal_S8e PF01201.17 KRH93332.1 - 5.2e-33 114.0 4.2 3.7e-31 107.9 2.9 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e SPOUT_MTase PF02590.12 KRH93332.1 - 0.56 9.9 6.1 2.8 7.6 4.2 2.0 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase DEAD PF00270.24 KRH93333.1 - 4.6e-07 29.4 0.1 1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KRH93333.1 - 0.021 14.6 5.8 0.022 14.5 0.0 2.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit T2SE PF00437.15 KRH93333.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KRH93333.1 - 0.04 13.1 0.2 0.087 12.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein FANCI_S2 PF14676.1 KRH93333.1 - 0.041 13.7 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 FANCI solenoid 2 RP-C_C PF11800.3 KRH93333.1 - 0.21 11.2 1.1 0.32 10.6 0.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Pam17 PF08566.5 KRH93333.1 - 0.21 11.2 2.6 0.89 9.2 1.8 1.9 1 1 0 1 1 1 0 Mitochondrial import protein Pam17 GDI PF00996.13 KRH93334.1 - 5e-62 209.6 1.4 5.2e-49 166.7 0.5 2.0 1 1 0 2 2 2 2 GDP dissociation inhibitor FANCI_S1 PF14675.1 KRH93335.1 - 0.0019 17.6 0.6 0.0035 16.7 0.2 1.6 1 1 0 1 1 1 1 FANCI solenoid 1 YqgF PF14639.1 KRH93335.1 - 0.061 12.8 0.1 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Antimicrobial_3 PF08025.6 KRH93335.1 - 0.23 11.2 2.8 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Spider antimicrobial peptide Cnd1 PF12717.2 KRH93335.1 - 0.65 9.8 7.1 1.1 9.1 0.9 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 rve PF00665.21 KRH93336.1 - 2.9e-27 95.1 0.0 7.2e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 KRH93336.1 - 6.3e-26 91.0 0.3 3.6e-25 88.5 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH93336.1 - 1.7e-10 40.7 0.1 4.5e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH93336.1 - 0.00054 20.4 0.2 0.0015 18.9 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KRH93336.1 - 0.00082 19.3 0.1 0.002 18.0 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH93336.1 - 0.0025 17.6 0.1 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_Tnp_IS240 PF13610.1 KRH93336.1 - 0.003 17.5 0.2 0.0089 15.9 0.1 1.8 1 0 0 1 1 1 1 DDE domain rve_3 PF13683.1 KRH93336.1 - 0.003 17.0 1.8 0.0064 15.9 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain DUF1900 PF08954.6 KRH93336.1 - 0.025 14.1 0.0 0.081 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) RVT_1 PF00078.22 KRH93337.1 - 1.5e-20 73.5 6.5 9.6e-20 70.8 0.1 3.8 4 0 0 4 4 4 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93337.1 - 8.3e-16 58.1 0.0 2.2e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.6 KRH93337.1 - 3.4e-07 30.2 0.1 7.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 KRH93337.1 - 0.0001 22.0 1.1 0.0001 22.0 0.8 2.3 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.1 KRH93337.1 - 0.0004 20.8 0.0 0.00095 19.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93337.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH93337.1 - 0.0036 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.1 KRH93337.1 - 0.032 13.7 0.2 0.11 11.9 0.1 2.1 1 0 0 1 1 1 0 Integrase core domain DNA_pol_E_B PF04042.11 KRH93338.1 - 1.8e-13 50.2 1.0 1.1e-12 47.6 0.7 2.0 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF243 PF03103.12 KRH93338.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF243) Med31 PF05669.7 KRH93339.1 - 4.2e-30 103.5 7.1 5.9e-30 103.0 4.9 1.2 1 0 0 1 1 1 1 SOH1 DUF3680 PF12441.3 KRH93339.1 - 0.06 13.2 0.7 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) TypeIII_RM_meth PF12564.3 KRH93339.1 - 2.5 8.1 7.3 0.69 9.9 1.0 2.5 2 1 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit PHD PF00628.24 KRH93340.1 - 1.3e-06 28.0 11.0 1.3e-06 28.0 7.6 1.7 2 0 0 2 2 2 1 PHD-finger ING PF12998.2 KRH93340.1 - 0.0009 19.4 1.9 0.0016 18.6 1.3 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF2779 PF11074.3 KRH93340.1 - 0.0014 18.7 1.5 0.0021 18.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) tRNA-synt_1e PF01406.14 KRH93340.1 - 0.015 14.3 2.0 0.021 13.9 1.4 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Bacillus_HBL PF05791.6 KRH93340.1 - 0.2 11.0 4.7 0.27 10.5 3.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ORC2 PF04084.9 KRH93341.1 - 2.9e-17 62.4 10.7 1.1e-09 37.6 5.3 3.0 2 1 0 2 2 2 2 Origin recognition complex subunit 2 Epsilon_antitox PF08998.6 KRH93341.1 - 0.0017 18.2 5.6 0.0024 17.7 0.1 2.9 2 1 1 3 3 3 1 Bacterial epsilon antitoxin DDE_Tnp_IS1595 PF12762.2 KRH93343.1 - 8.2e-30 103.6 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 KRH93343.1 - 2.1e-09 36.9 0.0 3.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family rve PF00665.21 KRH93343.1 - 0.00073 19.6 0.1 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Endonuc-dimeris PF09124.5 KRH93343.1 - 0.043 13.4 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation BTB_2 PF02214.17 KRH93344.1 - 0.13 12.5 0.5 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 BTB/POZ domain Peptidase_C48 PF02902.14 KRH93345.1 - 0.014 14.9 0.2 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Asp_protease_2 PF13650.1 KRH93346.1 - 1.8e-05 25.1 0.0 2.2e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93346.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH93346.1 - 0.038 13.9 0.0 0.51 10.2 0.0 1.9 1 1 1 2 2 2 0 Retroviral aspartyl protease PI3_PI4_kinase PF00454.22 KRH93347.1 - 7.9e-26 90.9 8.3 2e-25 89.6 0.4 3.1 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KRH93347.1 - 2.3e-10 39.6 0.0 5.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain RVT_1 PF00078.22 KRH93348.1 - 3.8e-16 59.0 0.0 5.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ndr PF03096.9 KRH93349.1 - 0.081 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Ndr family HTH_IclR PF09339.5 KRH93352.1 - 6.1e-05 22.5 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.1 KRH93352.1 - 0.00012 21.5 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain TrmB PF01978.14 KRH93352.1 - 0.00095 18.8 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 KRH93352.1 - 0.0014 18.2 0.1 0.0027 17.3 0.0 1.4 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.1 KRH93352.1 - 0.0057 16.0 0.4 0.075 12.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 KRH93352.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_5 PF01022.15 KRH93352.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LacI PF00356.16 KRH93352.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2435 PF10363.4 KRH93352.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HTH_20 PF12840.2 KRH93352.1 - 0.035 13.9 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.2 KRH93352.1 - 0.043 13.8 0.0 0.059 13.4 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.1 KRH93352.1 - 0.049 13.9 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Crp PF00325.15 KRH93352.1 - 0.06 12.8 0.2 0.18 11.3 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_36 PF13730.1 KRH93352.1 - 0.089 12.9 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.1 KRH93352.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.17 KRH93352.1 - 0.11 12.2 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 MarR family PC_rep PF01851.17 KRH93353.1 - 0.0042 17.2 0.0 0.0042 17.2 0.0 5.0 6 0 0 6 6 6 1 Proteasome/cyclosome repeat Mucin PF01456.12 KRH93353.1 - 3.9 7.2 18.6 10 5.8 12.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4485 PF14846.1 KRH93355.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) rve PF00665.21 KRH93356.1 - 1.8e-15 57.1 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain ApoO PF09769.4 KRH93356.1 - 0.022 14.4 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O DNA_pol_B PF00136.16 KRH93356.1 - 0.057 12.1 0.0 0.074 11.8 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase family B Ribosomal_L31e PF01198.14 KRH93356.1 - 0.094 12.3 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L31e zf-C2H2 PF00096.21 KRH93358.1 - 9.6e-05 22.4 0.8 9.6e-05 22.4 0.5 5.1 5 0 0 5 5 4 1 Zinc finger, C2H2 type zf-C3HC4 PF00097.20 KRH93358.1 - 0.00016 21.2 7.8 0.00016 21.2 5.4 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_6 PF13912.1 KRH93358.1 - 0.00048 19.9 0.3 0.00048 19.9 0.2 4.3 4 1 0 4 4 4 1 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 KRH93358.1 - 0.0037 16.9 7.1 0.0037 16.9 4.9 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 KRH93358.1 - 0.0046 17.1 0.3 0.0046 17.1 0.2 6.5 7 0 0 7 7 7 2 C2H2-type zinc finger zf-met PF12874.2 KRH93358.1 - 0.0048 17.0 28.0 0.0063 16.6 0.7 5.8 4 1 1 5 5 5 2 Zinc-finger of C2H2 type zf-RING_5 PF14634.1 KRH93358.1 - 0.0056 16.3 6.3 0.0056 16.3 4.4 3.9 3 2 0 3 3 2 1 zinc-RING finger domain zf-C2H2_jaz PF12171.3 KRH93358.1 - 0.019 15.0 0.6 0.019 15.0 0.4 4.7 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding GFA PF04828.9 KRH93358.1 - 0.09 12.7 5.5 14 5.7 0.1 4.2 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Trypan_glycop_C PF10659.4 KRH93358.1 - 0.35 11.1 0.1 0.35 11.1 0.1 3.8 3 1 0 3 3 2 0 Trypanosome variant surface glycoprotein C-terminal domain zf-C2H2_2 PF12756.2 KRH93358.1 - 0.91 9.6 31.9 1.7 8.7 10.0 4.3 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Lar_restr_allev PF14354.1 KRH93358.1 - 8 6.8 8.1 3.3 8.0 0.3 2.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar FLO_LFY PF01698.11 KRH93358.1 - 9.8 4.9 21.9 26 3.5 15.2 1.7 1 0 0 1 1 1 0 Floricaula / Leafy protein Sugar_tr PF00083.19 KRH93359.1 - 5e-23 81.4 45.3 5.8e-17 61.4 13.4 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KRH93359.1 - 2e-09 36.6 32.6 2e-09 36.6 22.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4396 PF14342.1 KRH93359.1 - 0.016 15.3 1.6 0.016 15.3 1.1 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4396) DUF4231 PF14015.1 KRH93359.1 - 4.3 7.3 19.7 0.99 9.4 1.0 4.1 2 2 1 3 3 3 0 Protein of unknown function (DUF4231) TGT PF01702.13 KRH93360.1 - 4.9e-67 225.6 0.5 8.9e-67 224.8 0.3 1.4 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PTR2 PF00854.16 KRH93361.1 - 3.6e-11 42.4 13.9 4.6e-11 42.1 9.6 1.2 1 0 0 1 1 1 1 POT family SNF2_N PF00176.18 KRH93363.1 - 1.4e-64 217.7 2.4 1.4e-64 217.7 1.7 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KRH93363.1 - 3e-14 52.6 0.0 8.5e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KRH93363.1 - 1.8e-06 27.5 0.0 5.4e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KRH93363.1 - 0.042 14.0 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Cucumo_2B PF03263.8 KRH93363.1 - 0.063 13.5 0.2 0.063 13.5 0.2 3.2 4 0 0 4 4 4 0 Cucumovirus protein 2B AAA_14 PF13173.1 KRH93363.1 - 0.089 12.6 0.2 0.089 12.6 0.1 3.9 2 1 1 3 3 3 0 AAA domain Homeobox PF00046.24 KRH93364.1 - 1.2e-15 56.8 2.4 4.6e-15 54.9 1.7 2.1 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH93364.1 - 0.03 14.0 0.1 0.086 12.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain Nol1_Nop2_Fmu PF01189.12 KRH93365.1 - 1e-36 126.7 0.1 8.3e-25 87.7 0.0 3.5 1 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KRH93365.1 - 0.0013 18.3 4.3 0.14 11.7 0.0 3.0 2 2 1 4 4 4 2 Methyltransferase domain Methyltransf_26 PF13659.1 KRH93365.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3362 PF11842.3 KRH93365.1 - 0.086 12.7 0.2 0.086 12.7 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3362) Mem_trans PF03547.13 KRH93365.1 - 0.89 7.7 4.7 6.8 4.8 0.2 2.1 2 0 0 2 2 2 0 Membrane transport protein Asparaginase_2 PF01112.13 KRH93365.1 - 2.4 6.7 9.5 1.6 7.3 0.4 2.2 2 0 0 2 2 2 0 Asparaginase DUF3639 PF12341.3 KRH93366.1 - 1.3 9.0 12.1 23 5.1 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) LRR_4 PF12799.2 KRH93368.1 - 0.22 11.1 5.7 1.3 8.7 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DOT1 PF08123.8 KRH93368.1 - 0.5 9.6 6.3 0.32 10.2 1.6 2.3 2 1 0 2 2 2 0 Histone methylation protein DOT1 LRR_6 PF13516.1 KRH93368.1 - 4.7 7.5 6.5 9.6 6.6 0.0 4.7 6 1 0 6 6 6 0 Leucine Rich repeat Got1 PF04178.7 KRH93369.1 - 0.03 14.4 14.0 0.78 9.8 9.7 2.1 1 1 0 1 1 1 0 Got1/Sft2-like family YrhK PF14145.1 KRH93369.1 - 2.1 8.0 8.4 0.14 11.8 2.2 1.8 2 1 0 2 2 2 0 YrhK-like protein RabGAP-TBC PF00566.13 KRH93370.1 - 4.8e-05 22.9 6.1 8e-05 22.2 4.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rad17 PF03215.10 KRH93370.1 - 0.005 15.5 4.4 0.0073 15.0 2.7 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein Rad10 PF03834.9 KRH93371.1 - 1e-19 69.9 1.6 1.4e-19 69.4 0.3 1.8 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) WAC_Acf1_DNA_bd PF10537.4 KRH93371.1 - 0.057 13.5 0.8 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal VWA_2 PF13519.1 KRH93372.1 - 2.3e-07 31.0 0.1 5e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Arrestin_N PF00339.24 KRH93373.1 - 8.2e-13 48.4 4.9 5.1e-10 39.3 0.3 2.9 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KRH93373.1 - 4.3e-05 23.6 5.5 0.078 13.0 0.2 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain IL22 PF14565.1 KRH93373.1 - 0.016 15.2 1.2 0.026 14.6 0.8 1.3 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Y_phosphatase PF00102.22 KRH93374.1 - 1e-22 80.6 0.4 4.7e-16 58.8 0.0 2.3 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 KRH93374.1 - 8.5e-07 28.6 0.2 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KRH93374.1 - 0.0047 16.9 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KRH93374.1 - 0.0049 17.1 0.1 0.043 14.0 0.0 2.4 3 0 0 3 3 3 1 Tyrosine phosphatase family RVT_1 PF00078.22 KRH93375.1 - 2.2e-23 82.7 0.9 2.6e-22 79.2 0.1 3.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93375.1 - 1.4e-19 70.3 0.0 6.8e-19 68.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93375.1 - 0.002 17.6 3.6 0.0024 17.3 0.5 2.7 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 KRH93376.1 - 0.15 12.1 1.7 0.79 9.8 0.1 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 KRH93377.1 - 3.1e-08 33.9 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 KRH93377.1 - 2.1e-07 30.4 0.1 3.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.5 KRH93377.1 - 3.2e-07 29.9 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93377.1 - 1.7e-05 24.6 0.2 3.3e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH93377.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 KRH93377.1 - 0.016 14.7 0.2 0.025 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.6 KRH93377.1 - 0.028 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 KRH93378.1 - 1.3e-18 67.1 0.1 2.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93378.1 - 3.7e-17 62.5 0.1 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93378.1 - 0.18 11.3 2.1 0.72 9.4 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain DUF747 PF05346.6 KRH93379.1 - 3.3e-41 141.4 9.6 4.5e-41 140.9 6.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3270 PF11674.3 KRH93379.1 - 0.001 19.0 0.6 0.001 19.0 0.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3270) DUF3552 PF12072.3 KRH93379.1 - 0.86 8.7 3.7 1.3 8.1 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Plasmid_Txe PF06769.8 KRH93380.1 - 0.027 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Plasmid encoded toxin Txe CRC_subunit PF08624.5 KRH93380.1 - 0.11 12.3 2.8 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit AAA_12 PF13087.1 KRH93380.1 - 0.15 11.3 1.7 0.22 10.8 1.2 1.4 1 1 0 1 1 1 0 AAA domain VASP_tetra PF08776.6 KRH93380.1 - 0.15 11.3 0.1 0.15 11.3 0.0 2.7 4 0 0 4 4 4 0 VASP tetramerisation domain SR-25 PF10500.4 KRH93381.1 - 5.5e-05 22.7 16.0 5.5e-05 22.7 11.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Zip PF02535.17 KRH93381.1 - 0.31 10.0 9.3 1.4 7.8 7.1 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter CMV_1a PF12467.3 KRH93381.1 - 3.4 8.0 14.4 0.71 10.2 5.4 2.3 2 1 0 2 2 2 0 Cucumber mosaic virus 1a protein family DDE_Tnp_IS1595 PF12762.2 KRH93383.1 - 0.00089 19.1 0.1 0.00098 18.9 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain SRP54_N PF02881.14 KRH93383.1 - 0.021 14.9 0.3 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain USP7_C2 PF14533.1 KRH93383.1 - 0.037 13.4 0.4 0.038 13.4 0.3 1.0 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal RVT_1 PF00078.22 KRH93384.1 - 4.8e-22 78.3 0.2 2e-21 76.3 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93384.1 - 8.7e-18 64.5 0.0 6.4e-17 61.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RNase_H PF00075.19 KRH93384.1 - 0.00018 21.8 0.1 0.00044 20.5 0.1 1.7 1 0 0 1 1 1 1 RNase H RVT_thumb PF06817.9 KRH93384.1 - 0.015 14.8 0.2 0.051 13.1 0.1 2.0 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVP PF00077.15 KRH93385.1 - 3.9e-07 29.9 0.6 1.4e-06 28.1 0.4 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 KRH93385.1 - 5.6e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93385.1 - 0.0001 21.8 0.1 0.0002 20.9 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KRH93385.1 - 0.0001 22.6 0.0 0.00047 20.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93385.1 - 0.00035 20.3 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF866 PF05907.8 KRH93386.1 - 0.026 14.0 12.9 0.25 10.8 0.8 3.3 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.8 KRH93386.1 - 0.065 12.9 0.2 0.065 12.9 0.2 2.7 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like Glyco_transf_20 PF00982.16 KRH93387.1 - 7.8e-61 205.9 1.1 4.4e-18 65.0 0.0 4.3 4 0 0 4 4 4 4 Glycosyltransferase family 20 TBPIP PF07106.8 KRH93389.1 - 1.3e-17 63.8 19.0 1.3e-17 63.8 13.2 3.1 2 1 1 3 3 3 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KRH93389.1 - 0.0009 18.9 16.0 0.0009 18.9 11.1 3.1 1 1 1 3 3 3 1 Mnd1 family Macoilin PF09726.4 KRH93389.1 - 0.0013 17.1 44.4 0.0016 16.8 30.8 1.0 1 0 0 1 1 1 1 Transmembrane protein KIP1 PF07765.7 KRH93389.1 - 0.0091 15.8 1.5 0.029 14.2 1.0 1.9 1 0 0 1 1 1 1 KIP1-like protein DUF1192 PF06698.6 KRH93389.1 - 0.012 15.3 7.6 0.13 12.0 0.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.6 KRH93389.1 - 0.59 10.0 12.2 1.6 8.7 0.7 3.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 KRH93389.1 - 2.9 8.3 6.3 70 3.8 4.2 3.5 1 1 0 1 1 1 0 SlyX Pox_A_type_inc PF04508.7 KRH93389.1 - 7.7 6.5 7.1 6.4 6.8 0.5 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Evr1_Alr PF04777.8 KRH93390.1 - 0.0089 15.9 0.2 0.0098 15.7 0.1 1.0 1 0 0 1 1 1 1 Erv1 / Alr family Takusan PF04822.8 KRH93390.1 - 0.011 15.5 6.2 0.012 15.3 4.3 1.0 1 0 0 1 1 1 0 Takusan RBD-FIP PF09457.5 KRH93390.1 - 0.17 11.7 1.4 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 FIP domain CENP-F_leu_zip PF10473.4 KRH93391.1 - 0.0011 18.8 7.0 0.0013 18.5 4.9 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 KRH93391.1 - 0.0052 16.7 4.6 0.007 16.3 3.2 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 KRH93391.1 - 0.013 15.1 4.2 0.031 13.8 2.9 1.6 1 1 0 1 1 1 0 IncA protein Rota_NSP4 PF01452.11 KRH93391.1 - 0.084 12.2 1.6 0.1 11.9 1.1 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein Erf4 PF10256.4 KRH93391.1 - 0.12 12.2 0.3 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF1192 PF06698.6 KRH93391.1 - 0.19 11.5 5.1 1.1 9.1 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ETRAMP PF09716.5 KRH93391.1 - 0.19 11.7 1.1 0.47 10.4 0.8 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4094 PF13334.1 KRH93391.1 - 0.23 11.8 3.4 1.7 9.1 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF4164 PF13747.1 KRH93391.1 - 0.27 11.3 5.9 1.7 8.8 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Mnd1 PF03962.10 KRH93391.1 - 0.33 10.5 4.4 0.46 10.1 3.1 1.2 1 0 0 1 1 1 0 Mnd1 family Baculo_p24 PF05073.7 KRH93391.1 - 0.33 10.4 3.2 0.38 10.3 2.2 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF1664 PF07889.7 KRH93391.1 - 0.54 10.0 4.0 2.4 7.9 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 KRH93391.1 - 0.93 9.9 4.2 1.6 9.2 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.6 KRH93391.1 - 1.5 8.8 6.0 12 5.8 1.1 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.15 KRH93391.1 - 3.3 7.5 9.5 3.1 7.6 1.6 2.1 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 KRH93391.1 - 7 6.2 10.2 6.9 6.2 1.4 2.3 1 1 0 2 2 2 0 Septum formation initiator rve PF00665.21 KRH93392.1 - 9.3e-17 61.2 0.1 2e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93392.1 - 0.0086 15.5 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Cecropin PF00272.14 KRH93392.1 - 0.11 12.1 0.4 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Cecropin family zf-CCHC PF00098.18 KRH93393.1 - 4.9e-05 23.0 0.2 9.2e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_L7Ae PF01248.21 KRH93395.1 - 1.7e-08 33.8 0.6 2e-08 33.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 KRH93395.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF2574 PF10836.3 KRH93395.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Mod_r PF07200.8 KRH93395.1 - 0.034 14.0 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF241 PF03087.9 KRH93395.1 - 0.053 13.0 1.3 0.063 12.7 0.9 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function PepSY_TM PF03929.11 KRH93396.1 - 0.017 15.4 0.2 0.025 14.9 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix RVT_1 PF00078.22 KRH93398.1 - 5.8e-23 81.3 0.2 1.3e-22 80.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93398.1 - 4.5e-16 59.0 0.9 1e-15 57.9 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.15 KRH93398.1 - 1.7e-08 34.2 2.2 3e-08 33.4 0.5 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 KRH93398.1 - 0.0056 16.7 1.1 0.0056 16.7 0.8 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 KRH93399.1 - 1.2e-19 70.6 0.1 4.9e-18 65.3 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain RVT_3 PF13456.1 KRH93399.1 - 0.014 15.1 0.1 0.045 13.5 0.1 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like rve_3 PF13683.1 KRH93399.1 - 0.027 13.9 0.6 0.11 11.9 0.0 2.4 3 0 0 3 3 3 0 Integrase core domain RVT_1 PF00078.22 KRH93400.1 - 1.4e-10 40.8 0.1 8.6e-10 38.3 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 KRH93400.1 - 3.1e-06 27.6 0.0 9.1e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93400.1 - 0.00013 21.7 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH93400.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH93400.1 - 0.027 14.4 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Streptin-Immun PF11083.3 KRH93401.1 - 0.021 14.8 0.4 0.021 14.8 0.3 2.2 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein 2OG-FeII_Oxy_3 PF13640.1 KRH93403.1 - 8e-12 45.5 0.2 2.4e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KRH93403.1 - 0.029 14.6 0.0 0.08 13.2 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2985 PF11204.3 KRH93404.1 - 0.019 14.6 0.1 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) TMEM52 PF14979.1 KRH93404.1 - 0.13 12.1 0.8 0.6 10.0 0.2 1.9 1 1 1 2 2 2 0 Transmembrane 52 Sec23_trunk PF04811.10 KRH93405.1 - 1.4e-12 47.5 0.1 5.4e-12 45.6 0.1 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 KRH93405.1 - 0.0021 18.5 0.1 0.048 14.1 0.0 2.5 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KRH93405.1 - 0.0071 16.0 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat FA_desaturase PF00487.19 KRH93406.1 - 0.1 11.9 2.5 0.17 11.2 1.7 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Ninjurin PF04923.7 KRH93406.1 - 0.89 9.3 5.3 19 5.0 0.1 2.7 2 1 0 2 2 2 0 Ninjurin Nsp1_C PF05064.8 KRH93408.1 - 0.0016 18.0 1.4 0.0016 18.0 1.0 3.1 3 0 0 3 3 3 1 Nsp1-like C-terminal region V_ATPase_I PF01496.14 KRH93408.1 - 0.015 13.2 2.6 0.021 12.7 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec8_exocyst PF04048.9 KRH93408.1 - 0.015 14.8 3.3 0.11 12.1 0.5 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain UPF0449 PF15136.1 KRH93408.1 - 0.042 14.0 4.0 0.053 13.7 1.4 2.2 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 TFX_C PF14601.1 KRH93408.1 - 0.089 12.5 0.3 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Keratin_B2 PF01500.12 KRH93408.1 - 0.11 12.2 1.1 0.16 11.7 0.8 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Sec20 PF03908.8 KRH93408.1 - 2.2 8.0 9.4 0.058 13.0 0.7 2.5 3 1 0 3 3 3 0 Sec20 DDE_Tnp_IS1595 PF12762.2 KRH93411.1 - 1.1e-05 25.3 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain T4_baseplate PF12322.3 KRH93412.1 - 0.00065 19.0 0.3 0.0007 18.9 0.2 1.1 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.14 KRH93412.1 - 0.0018 17.6 2.4 0.0031 16.9 1.7 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.11 KRH93412.1 - 0.0031 17.1 2.0 0.026 14.2 1.4 2.0 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain Elf1 PF05129.8 KRH93412.1 - 0.018 14.6 0.4 0.022 14.4 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 KRH93412.1 - 0.027 13.8 0.5 0.031 13.6 0.4 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-ribbon_3 PF13248.1 KRH93412.1 - 0.055 12.7 0.3 0.1 11.8 0.1 1.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KRH93412.1 - 0.065 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PapB PF03333.8 KRH93412.1 - 0.076 12.8 0.2 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein DUF2225 PF09986.4 KRH93412.1 - 0.13 11.7 1.2 0.2 11.0 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_5 PF13719.1 KRH93412.1 - 0.48 10.0 2.8 1.8 8.2 1.9 1.9 1 1 0 1 1 1 0 zinc-ribbon domain NAP PF00956.13 KRH93414.1 - 1.3e-06 27.7 5.9 1.3e-06 27.7 4.1 1.5 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) Ricin_B_lectin PF00652.17 KRH93415.1 - 1.4e-07 31.5 0.0 3.8e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KRH93415.1 - 0.0012 19.2 0.1 0.14 12.5 0.0 2.4 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KRH93415.1 - 0.0093 15.3 1.7 0.022 14.1 0.8 2.0 1 1 0 1 1 1 1 Cytolethal distending toxin A/C family HAUS-augmin3 PF14932.1 KRH93415.1 - 0.053 12.7 2.0 0.078 12.1 1.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 vATP-synt_E PF01991.13 KRH93416.1 - 0.017 14.4 6.0 0.019 14.2 4.2 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Cas_Cmr5 PF09701.5 KRH93416.1 - 0.18 11.9 2.2 0.26 11.4 1.6 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) DUF1843 PF08898.5 KRH93416.1 - 0.49 10.4 2.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Nsp1_C PF05064.8 KRH93416.1 - 0.65 9.6 8.9 1.5 8.5 0.5 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Corona_S2 PF01601.11 KRH93416.1 - 1 7.3 5.7 1.1 7.2 3.9 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FlxA PF14282.1 KRH93416.1 - 3.2 7.7 8.5 4.3 7.3 5.9 1.2 1 0 0 1 1 1 0 FlxA-like protein Patatin PF01734.17 KRH93418.1 - 1.1e-08 35.3 0.0 7e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase HSP90 PF00183.13 KRH93418.1 - 0.1 11.0 0.0 2.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Hsp90 protein zf-UBR PF02207.15 KRH93418.1 - 0.87 9.3 6.2 2.3 7.9 4.3 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) adh_short PF00106.20 KRH93419.1 - 1.1e-18 67.7 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KRH93419.1 - 9.3e-07 28.8 0.2 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KRH93419.1 - 1.3e-05 24.9 0.0 8.1e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 KR domain ApbA PF02558.11 KRH93419.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KRH93419.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KRH93419.1 - 0.025 13.4 0.5 0.058 12.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KRH93419.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Wax2_C PF12076.3 KRH93419.1 - 0.053 13.2 0.1 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain Epimerase PF01370.16 KRH93419.1 - 0.11 11.9 0.2 0.18 11.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family dCMP_cyt_deam_1 PF00383.17 KRH93420.1 - 9.7e-23 79.7 0.1 1.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Helicase_C PF00271.26 KRH93421.1 - 1.2e-15 57.1 0.0 2.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MAS20 PF02064.10 KRH93421.1 - 8.9 6.2 7.5 1.2 9.0 0.4 2.8 2 1 1 3 3 3 0 MAS20 protein import receptor zf-CHY PF05495.7 KRH93423.1 - 2.3e-13 50.1 12.5 2.3e-13 50.1 8.7 3.7 3 1 0 3 3 3 1 CHY zinc finger HALZ PF02183.13 KRH93424.1 - 0.0011 18.6 1.7 0.002 17.7 0.3 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper GvpK PF05121.7 KRH93424.1 - 0.0022 17.8 1.8 0.0039 16.9 1.2 1.4 1 0 0 1 1 1 1 Gas vesicle protein K Atg14 PF10186.4 KRH93424.1 - 0.0078 15.1 5.2 0.011 14.7 3.6 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 KRH93424.1 - 0.011 15.6 3.3 0.017 14.9 2.3 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain KLRAQ PF10205.4 KRH93424.1 - 0.013 15.4 4.7 0.013 15.4 3.3 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein bZIP_1 PF00170.16 KRH93424.1 - 0.038 13.9 2.6 0.038 13.9 1.8 2.7 2 1 1 3 3 3 0 bZIP transcription factor LON PF02190.11 KRH93424.1 - 0.051 13.2 0.8 0.06 13.0 0.5 1.3 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain Bap31 PF05529.7 KRH93424.1 - 0.065 12.6 4.3 0.11 12.0 3.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3782 PF12644.2 KRH93424.1 - 0.069 12.9 0.4 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Rootletin PF15035.1 KRH93424.1 - 0.11 12.4 7.4 0.17 11.8 5.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1640 PF07798.6 KRH93424.1 - 0.15 12.1 7.4 0.28 11.1 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 KRH93424.1 - 0.26 11.0 10.7 1.3 8.7 7.4 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 KRH93424.1 - 0.69 9.4 5.5 1.4 8.4 2.6 2.3 1 1 1 2 2 2 0 Septum formation initiator SYCE1 PF15233.1 KRH93424.1 - 0.93 9.4 9.7 0.91 9.4 6.5 1.4 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 IFP_35_N PF07334.8 KRH93424.1 - 1.5 8.8 8.7 0.29 11.1 2.9 2.1 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF972 PF06156.8 KRH93424.1 - 8.8 6.7 11.2 2.9 8.2 5.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ERO1 PF04137.10 KRH93425.1 - 5.3e-17 61.8 12.7 2e-16 59.9 4.6 2.9 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Invas_SpaK PF03519.9 KRH93425.1 - 0.022 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Invasion protein B family DUF4488 PF14869.1 KRH93425.1 - 0.07 12.7 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) AAA PF00004.24 KRH93426.1 - 8e-45 152.2 0.0 1.5e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH93426.1 - 2e-07 30.7 0.1 1.2e-06 28.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KRH93426.1 - 2.5e-07 30.9 0.1 2.9e-05 24.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KRH93426.1 - 6.9e-06 26.0 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KRH93426.1 - 8.4e-06 26.6 0.6 0.00014 22.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 KRH93426.1 - 1.2e-05 24.3 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KRH93426.1 - 5.3e-05 23.2 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KRH93426.1 - 0.00026 20.1 0.0 0.00054 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KRH93426.1 - 0.0006 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH93426.1 - 0.00063 19.4 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KRH93426.1 - 0.00079 19.1 0.1 0.022 14.4 0.1 2.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KRH93426.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KRH93426.1 - 0.001 19.3 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KRH93426.1 - 0.0017 18.4 0.0 0.0072 16.4 0.0 2.0 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 KRH93426.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KRH93426.1 - 0.002 17.2 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KRH93426.1 - 0.0022 17.6 0.0 0.57 9.8 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_25 PF13481.1 KRH93426.1 - 0.0023 17.3 0.4 0.085 12.2 0.1 2.3 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KRH93426.1 - 0.0027 16.9 0.1 0.017 14.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KRH93426.1 - 0.0029 17.5 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KRH93426.1 - 0.0054 15.5 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 KRH93426.1 - 0.0076 15.8 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KRH93426.1 - 0.0089 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KRH93426.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 NTPase KaiC PF06745.8 KRH93426.1 - 0.027 13.5 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 KRH93426.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 KRH93426.1 - 0.037 12.8 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 KRH93426.1 - 0.041 13.3 0.0 0.14 11.6 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 KRH93426.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 KRH93426.1 - 0.074 13.3 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 KRH93426.1 - 0.075 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LSM PF01423.17 KRH93427.1 - 2.7e-15 55.6 0.3 4.3e-15 55.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain Prefoldin PF02996.12 KRH93428.1 - 0.00078 19.0 0.4 0.00093 18.8 0.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.6 KRH93428.1 - 0.18 11.6 1.1 0.19 11.5 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) G_glu_transpept PF01019.16 KRH93429.1 - 2.8e-140 468.2 0.0 3.2e-140 468.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.20 KRH93430.1 - 3.8e-25 88.5 0.2 1.3e-19 70.3 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93430.1 - 4.8e-14 52.0 0.2 1.5e-11 43.8 0.1 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH93430.1 - 0.00043 19.3 0.8 0.011 14.6 0.1 2.5 3 0 0 3 3 3 1 Kinase-like YrbL-PhoP_reg PF10707.4 KRH93430.1 - 0.0052 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Sua5_yciO_yrdC PF01300.13 KRH93431.1 - 6.4e-32 110.2 0.0 4.9e-30 104.0 0.0 2.4 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KRH93431.1 - 2e-11 44.0 0.0 3.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF2624 PF11116.3 KRH93431.1 - 0.086 13.3 0.3 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) PRK PF00485.13 KRH93434.1 - 6.5e-17 61.7 0.1 1.4e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KRH93434.1 - 9.6e-09 35.6 0.4 2.3e-08 34.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KRH93434.1 - 9.9e-09 36.0 0.0 2.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH93434.1 - 1.3e-06 28.5 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KRH93434.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KRH93434.1 - 1.4e-05 25.0 0.0 3.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 KRH93434.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 KRH93434.1 - 2.6e-05 24.1 0.2 0.00028 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KRH93434.1 - 3.9e-05 22.8 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KRH93434.1 - 0.00074 19.6 0.0 0.002 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Dna2 PF08696.6 KRH93434.1 - 0.0019 17.5 1.0 0.0054 16.0 0.0 2.1 2 1 0 2 2 2 1 DNA replication factor Dna2 KTI12 PF08433.5 KRH93434.1 - 0.0024 17.1 1.2 0.0032 16.7 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 T2SE PF00437.15 KRH93434.1 - 0.0029 16.5 0.7 0.0054 15.6 0.3 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KRH93434.1 - 0.0051 16.4 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KRH93434.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF258 PF03193.11 KRH93434.1 - 0.0059 15.8 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KRH93434.1 - 0.0059 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 KRH93434.1 - 0.0063 16.2 0.5 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 KRH93434.1 - 0.0064 16.7 0.1 0.0064 16.7 0.0 2.9 1 1 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 KRH93434.1 - 0.0076 15.7 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UPF0079 PF02367.12 KRH93434.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KRH93434.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 KRH93434.1 - 0.019 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KRH93434.1 - 0.02 14.8 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KRH93434.1 - 0.021 14.5 0.0 0.067 12.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ANF_receptor PF01094.23 KRH93434.1 - 0.025 13.4 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region RNA12 PF10443.4 KRH93434.1 - 0.046 12.2 0.0 0.046 12.2 0.0 2.0 1 1 1 2 2 2 0 RNA12 protein ArgK PF03308.11 KRH93434.1 - 0.083 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 KRH93434.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KRH93434.1 - 0.086 12.7 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 KRH93434.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TT_ORF1 PF02956.9 KRH93434.1 - 0.74 8.1 6.5 1.2 7.5 4.5 1.3 1 0 0 1 1 1 0 TT viral orf 1 PUA PF01472.15 KRH93435.1 - 3.2e-05 23.5 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PUA domain DUF1599 PF07659.6 KRH93435.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1599) Glutaredoxin PF00462.19 KRH93436.1 - 5.6e-11 42.2 0.0 1.6e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.10 KRH93436.1 - 0.0039 17.1 1.0 0.0059 16.5 0.1 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein PBP_dimer PF03717.10 KRH93436.1 - 0.029 14.4 2.0 0.055 13.5 1.4 1.5 1 1 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Thioredoxin_2 PF13098.1 KRH93436.1 - 0.057 13.6 0.6 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain P-mevalo_kinase PF04275.9 KRH93436.1 - 0.069 12.8 3.1 0.077 12.7 0.8 1.9 1 1 0 2 2 2 0 Phosphomevalonate kinase IL2 PF00715.12 KRH93436.1 - 0.66 9.7 2.9 2.2 7.9 0.9 2.1 1 1 1 2 2 2 0 Interleukin 2 DUF1435 PF07256.7 KRH93437.1 - 0.032 14.2 1.1 0.035 14.0 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Hexapep PF00132.19 KRH93438.1 - 1.6e-05 24.1 1.3 0.00074 18.9 0.2 2.7 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KRH93438.1 - 0.17 11.5 4.8 0.97 9.0 0.2 2.8 1 1 2 3 3 2 0 Hexapeptide repeat of succinyl-transferase DDE_Tnp_1_7 PF13843.1 KRH93439.1 - 9.3e-24 84.1 1.7 1.1e-23 83.9 1.2 1.0 1 0 0 1 1 1 1 Transposase IS4 rve PF00665.21 KRH93440.1 - 4e-11 43.0 0.1 4.7e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93440.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain UPF0004 PF00919.15 KRH93440.1 - 0.15 11.9 0.1 0.43 10.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein family UPF0004 Histone PF00125.19 KRH93441.1 - 8.6e-19 67.4 0.1 1.9e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KRH93441.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 KRH93441.1 - 0.00016 21.6 1.1 0.00034 20.6 0.0 2.1 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KRH93441.1 - 0.00017 21.7 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Cytochrom_B562 PF07361.6 KRH93441.1 - 0.0086 16.4 2.0 0.31 11.4 0.6 2.1 2 0 0 2 2 2 1 Cytochrome b562 DDE_Tnp_2 PF04693.7 KRH93441.1 - 0.086 11.8 0.1 0.097 11.6 0.1 1.2 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 zf-CCCH PF00642.19 KRH93443.1 - 5.7e-05 22.6 0.7 5.7e-05 22.6 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KRH93443.1 - 0.0077 16.1 1.4 0.0077 16.1 0.9 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type DUF4065 PF13274.1 KRH93443.1 - 0.2 12.4 2.5 0.51 11.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DapH_N PF08503.5 KRH93444.1 - 0.014 15.5 3.2 0.025 14.6 1.8 1.8 1 1 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal G10 PF01125.12 KRH93445.1 - 5.8e-28 97.2 7.6 6.8e-28 97.0 5.2 1.1 1 0 0 1 1 1 1 G10 protein ORF6N PF10543.4 KRH93445.1 - 0.023 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 ORF6N domain PEMT PF04191.8 KRH93446.1 - 0.0037 17.3 3.5 0.0037 17.3 2.4 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase Evr1_Alr PF04777.8 KRH93447.1 - 3.3e-27 94.2 0.7 8e-27 92.9 0.2 1.8 2 0 0 2 2 2 1 Erv1 / Alr family ABC1 PF03109.11 KRH93448.1 - 1.4e-14 54.1 0.2 8.1e-14 51.6 0.1 2.1 1 1 0 1 1 1 1 ABC1 family Pkinase PF00069.20 KRH93448.1 - 4.8e-10 39.0 5.4 3e-09 36.4 3.8 2.1 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KRH93448.1 - 5.7e-07 29.0 2.2 9.7e-07 28.3 0.4 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 KRH93448.1 - 9.1e-07 28.1 0.9 6.2e-06 25.4 0.4 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KRH93448.1 - 0.01 15.5 0.1 0.06 13.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nol1_Nop2_Fmu PF01189.12 KRH93449.1 - 1.1e-22 80.7 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family RrnaAD PF00398.15 KRH93449.1 - 0.0041 16.1 0.0 0.0077 15.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 KRH93449.1 - 0.0062 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Tox-MPTase2 PF15638.1 KRH93449.1 - 0.0099 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase toxin 2 Cons_hypoth95 PF03602.10 KRH93449.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KRH93449.1 - 0.056 13.0 0.4 0.12 11.9 0.3 1.6 1 1 0 1 1 1 0 Methyltransferase domain La PF05383.12 KRH93450.1 - 1.2e-12 47.4 0.1 3.9e-12 45.7 0.1 2.0 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KRH93450.1 - 8.4e-08 32.0 0.4 2.4e-06 27.4 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KRH93450.1 - 2.4e-06 27.0 0.1 2.4e-06 27.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH93450.1 - 0.23 11.3 2.9 0.35 10.7 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DM13 PF10517.4 KRH93450.1 - 5.1 7.5 8.7 0.75 10.2 0.9 3.1 2 1 2 4 4 4 0 Electron transfer DM13 RVT_1 PF00078.22 KRH93454.1 - 5.5e-23 81.4 0.5 8.3e-22 77.5 0.3 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.3 KRH93454.1 - 9.4e-17 61.1 13.5 2.5e-16 59.8 5.8 2.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain LCAT PF02450.10 KRH93455.1 - 3.9e-25 88.6 0.3 1.4e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 KRH93455.1 - 9.2e-09 35.2 0.1 1.6e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.2 KRH93455.1 - 0.00041 20.2 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KRH93455.1 - 0.013 14.7 2.2 1.3 8.2 0.0 3.2 3 1 0 3 3 3 0 Putative serine esterase (DUF676) DUF900 PF05990.7 KRH93455.1 - 0.029 13.6 0.0 0.077 12.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KRH93455.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1411 PF07199.6 KRH93457.1 - 0.027 13.9 0.8 0.027 13.9 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) Toxin_2 PF00451.14 KRH93457.1 - 8.4 6.5 11.7 3.3e+02 1.4 8.1 2.3 1 1 0 1 1 1 0 Scorpion short toxin, BmKK2 DUF1199 PF06712.6 KRH93458.1 - 0.071 12.9 2.2 36 4.2 0.0 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1199) Ribosomal_L7Ae PF01248.21 KRH93459.1 - 6.7e-23 80.0 0.5 1.2e-22 79.1 0.2 1.6 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KRH93459.1 - 0.0015 18.4 0.1 0.0018 18.1 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 rve PF00665.21 KRH93461.1 - 1.2e-09 38.3 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93461.1 - 0.00071 19.0 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Maelstrom PF13017.1 KRH93461.1 - 0.1 12.0 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 piRNA pathway germ-plasm component zf-CCHC PF00098.18 KRH93463.1 - 2.5e-06 27.1 2.6 4.2e-06 26.4 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CHC2 PF01807.15 KRH93463.1 - 0.018 14.5 0.3 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 CHC2 zinc finger zf-CCHC_6 PF15288.1 KRH93463.1 - 0.052 13.2 0.7 0.088 12.4 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KRH93463.1 - 0.59 9.8 7.2 0.082 12.5 2.1 1.9 2 1 0 2 2 2 0 Zinc knuckle Integrase_DNA PF02920.10 KRH93463.1 - 5.6 6.4 7.6 3 7.3 2.8 2.1 2 1 0 2 2 2 0 DNA binding domain of tn916 integrase Sec16_C PF12931.2 KRH93465.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DUF778 PF05608.7 KRH93465.1 - 0.083 12.8 0.2 0.19 11.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) IRK PF01007.15 KRH93466.1 - 0.065 12.0 0.5 0.066 11.9 0.4 1.0 1 0 0 1 1 1 0 Inward rectifier potassium channel DUF3828 PF12883.2 KRH93467.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) DDE_3 PF13358.1 KRH93467.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Actin PF00022.14 KRH93468.1 - 2.6e-09 35.9 0.0 1.5e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Actin CobT PF06213.7 KRH93468.1 - 0.36 9.9 10.5 0.74 8.8 5.8 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF2681 PF10883.3 KRH93469.1 - 0.015 15.5 1.5 0.12 12.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) TMEMspv1-c74-12 PF11044.3 KRH93469.1 - 0.064 12.8 1.0 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Vpu PF00558.14 KRH93469.1 - 0.073 12.6 0.9 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Vpu protein DUF1247 PF06851.6 KRH93469.1 - 0.11 12.1 3.1 0.19 11.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) CoatB PF10389.4 KRH93469.1 - 0.17 11.7 1.0 0.36 10.7 0.7 1.5 1 1 0 1 1 1 0 Bacteriophage coat protein B zf-CHY PF05495.7 KRH93470.1 - 0.098 12.8 1.8 0.11 12.6 1.2 1.1 1 0 0 1 1 1 0 CHY zinc finger tRNA-synt_2b PF00587.20 KRH93471.1 - 1.5e-40 138.6 0.9 3.1e-40 137.5 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KRH93471.1 - 2.8e-15 56.0 0.3 6.5e-15 54.8 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KRH93471.1 - 9.5e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain INT_SG_DDX_CT_C PF15300.1 KRH93471.1 - 0.0022 17.4 0.1 0.0082 15.5 0.0 2.0 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus Rab5-bind PF09311.6 KRH93472.1 - 9.9 6.0 17.1 1.9 8.3 3.7 2.6 2 1 0 2 2 2 0 Rabaptin-like protein DER1 PF04511.10 KRH93473.1 - 7.3e-38 130.0 21.0 9.2e-38 129.7 14.5 1.1 1 0 0 1 1 1 1 Der1-like family Gastrin PF00918.12 KRH93473.1 - 0.062 14.1 2.0 0.13 13.0 1.4 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family E1-E2_ATPase PF00122.15 KRH93474.1 - 2.2e-15 56.3 0.0 6e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KRH93474.1 - 5.6e-13 49.4 0.0 1.3e-12 48.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KRH93474.1 - 8.9e-11 42.6 0.0 4.1e-09 37.1 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KRH93474.1 - 2.7e-10 40.1 0.1 2.7e-10 40.1 0.1 3.2 3 1 0 3 3 3 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 KRH93474.1 - 5.2e-10 39.1 0.1 1.5e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit RVT_1 PF00078.22 KRH93475.1 - 2.5e-27 95.6 0.4 5.2e-27 94.6 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93475.1 - 2.3e-21 76.1 0.0 5.2e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93475.1 - 0.0093 15.4 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain eIF3g PF12353.3 KRH93476.1 - 0.0021 17.9 1.1 0.0038 17.1 0.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2136 PF09907.4 KRH93476.1 - 0.068 13.2 0.3 3.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2136) EF-hand_8 PF13833.1 KRH93477.1 - 0.00012 21.5 1.1 0.00032 20.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KRH93477.1 - 0.0032 17.5 1.7 0.0086 16.1 0.3 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KRH93477.1 - 0.0082 15.9 2.1 2.9 8.0 0.0 3.5 3 1 2 5 5 5 2 EF-hand domain Hydrolase_3 PF08282.7 KRH93477.1 - 0.0088 15.6 2.2 0.012 15.2 1.5 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NADPH_Ox PF08414.5 KRH93477.1 - 0.0093 16.0 0.6 0.52 10.4 0.1 2.5 1 1 0 2 2 2 1 Respiratory burst NADPH oxidase Dehydratase_SU PF02287.10 KRH93477.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Dehydratase small subunit YhdB PF14148.1 KRH93477.1 - 0.064 13.0 0.6 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 YhdB-like protein EF-hand_1 PF00036.27 KRH93477.1 - 0.078 12.3 0.0 0.078 12.3 0.0 3.7 4 1 1 5 5 5 0 EF hand EF-hand_5 PF13202.1 KRH93477.1 - 0.08 12.3 0.0 0.48 9.8 0.0 2.3 2 0 0 2 2 2 0 EF hand zf-RING_5 PF14634.1 KRH93478.1 - 0.0011 18.6 11.9 0.0028 17.3 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Spt4 PF06093.8 KRH93478.1 - 0.024 14.4 2.5 0.044 13.6 1.2 1.9 1 1 0 1 1 1 0 Spt4/RpoE2 zinc finger zf-RING_6 PF14835.1 KRH93478.1 - 0.12 12.2 2.2 0.22 11.3 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein XkdW PF09636.5 KRH93478.1 - 0.18 11.7 0.9 0.31 10.9 0.2 1.8 2 0 0 2 2 2 0 XkdW protein UDPGP PF01704.13 KRH93481.1 - 3.4e-07 29.1 0.0 4.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CDP-OH_P_transf PF01066.16 KRH93482.1 - 6.6e-14 52.0 1.5 6.6e-14 52.0 1.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Neur_chan_memb PF02932.11 KRH93482.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 KRH93482.1 - 0.021 13.1 1.9 0.033 12.5 1.3 1.4 1 1 0 1 1 1 0 Membrane transport protein UQ_con PF00179.21 KRH93483.1 - 8.9e-38 128.8 0.0 1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spc7 PF08317.6 KRH93484.1 - 0.0028 16.3 2.4 0.0029 16.3 1.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein OmpH PF03938.9 KRH93484.1 - 0.0063 16.4 1.2 0.0081 16.1 0.8 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DivIC PF04977.10 KRH93484.1 - 0.007 15.8 3.5 0.011 15.1 2.4 1.3 1 0 0 1 1 1 1 Septum formation initiator GrpE PF01025.14 KRH93484.1 - 0.01 15.3 2.7 0.014 14.9 1.9 1.2 1 0 0 1 1 1 0 GrpE DUF874 PF05917.6 KRH93484.1 - 0.01 14.7 2.7 0.011 14.6 1.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Ax_dynein_light PF10211.4 KRH93484.1 - 0.013 15.3 3.5 0.015 15.1 2.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Borrelia_P83 PF05262.6 KRH93484.1 - 0.014 13.6 4.8 0.014 13.7 3.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4337 PF14235.1 KRH93484.1 - 0.015 15.1 1.8 0.022 14.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Exonuc_VII_L PF02601.10 KRH93484.1 - 0.018 14.2 3.6 0.02 14.1 2.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMCO5 PF14992.1 KRH93484.1 - 0.019 14.1 3.2 0.019 14.1 2.2 1.1 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 KRH93484.1 - 0.024 12.4 1.2 0.024 12.5 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4041 PF13250.1 KRH93484.1 - 0.029 13.9 2.1 1.9 8.1 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4041) APG6 PF04111.7 KRH93484.1 - 0.033 13.2 2.5 0.034 13.2 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TelA PF05816.6 KRH93484.1 - 0.039 12.6 1.7 0.053 12.2 1.2 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Atg14 PF10186.4 KRH93484.1 - 0.06 12.2 2.7 0.08 11.8 1.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 KRH93484.1 - 0.07 12.8 10.9 0.033 13.9 6.2 1.4 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 KRH93484.1 - 0.074 13.0 0.3 5.3 7.1 0.0 2.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF3186 PF11382.3 KRH93484.1 - 0.16 11.0 0.8 0.19 10.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) EMP24_GP25L PF01105.19 KRH93484.1 - 0.16 11.6 2.3 0.23 11.1 1.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prefoldin_2 PF01920.15 KRH93484.1 - 0.17 11.6 9.7 0.32 10.7 6.8 1.5 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KRH93484.1 - 0.19 11.3 0.7 0.19 11.3 0.5 1.1 1 0 0 1 1 1 0 IncA protein Sec8_exocyst PF04048.9 KRH93484.1 - 0.26 10.9 5.0 0.54 9.8 3.5 1.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF3552 PF12072.3 KRH93484.1 - 0.36 10.0 9.2 0.048 12.8 3.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1043 PF06295.7 KRH93484.1 - 1.2 8.8 10.6 44 3.7 7.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Prefoldin PF02996.12 KRH93484.1 - 1.2 8.8 8.1 5.8 6.5 5.6 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF327 PF03885.8 KRH93484.1 - 4.3 7.1 9.5 7.3 6.4 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF327) RRF PF01765.14 KRH93484.1 - 5.2 6.5 9.9 8.9 5.7 6.9 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Bromodomain PF00439.20 KRH93485.1 - 2.2e-23 81.9 1.4 3.7e-23 81.2 1.0 1.3 1 0 0 1 1 1 1 Bromodomain zf-DHHC PF01529.15 KRH93488.1 - 3.8e-14 52.4 17.9 3.8e-14 52.4 12.4 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase RFC1 PF08519.7 KRH93489.1 - 7.2e-20 71.3 0.5 1.3e-19 70.4 0.3 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KRH93489.1 - 9.5e-12 44.9 1.5 3.6e-11 43.0 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KRH93489.1 - 2.2e-11 44.1 0.0 4.7e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH93489.1 - 7.8e-06 26.0 0.1 0.00037 20.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH93489.1 - 3.5e-05 23.8 0.0 7.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KRH93489.1 - 6.8e-05 23.0 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.10 KRH93489.1 - 0.00022 20.0 0.0 0.00022 20.0 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KRH93489.1 - 0.0004 20.2 0.3 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KRH93489.1 - 0.0017 19.1 0.0 0.0052 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KRH93489.1 - 0.003 17.0 0.1 0.071 12.6 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KRH93489.1 - 0.0043 16.6 0.2 0.0072 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KRH93489.1 - 0.0043 16.0 0.0 0.013 14.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KRH93489.1 - 0.0076 15.7 0.0 0.022 14.3 0.0 1.8 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.11 KRH93489.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NTPase_1 PF03266.10 KRH93489.1 - 0.023 14.4 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 0 NTPase Mg_chelatase PF01078.16 KRH93489.1 - 0.027 13.6 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KRH93489.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KRH93489.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 KRH93489.1 - 0.031 13.2 0.2 0.22 10.4 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KRH93489.1 - 0.044 13.3 0.0 1.2 8.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KRH93489.1 - 0.051 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KRH93490.1 - 4e-10 38.9 12.8 1.3e-08 34.0 7.4 2.5 1 1 0 1 1 1 1 TIP49 C-terminus B3 PF02362.16 KRH93490.1 - 0.00048 19.7 0.1 0.025 14.2 0.0 2.6 2 0 0 2 2 2 1 B3 DNA binding domain Asp_decarbox PF02261.11 KRH93490.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartate decarboxylase MS_channel PF00924.13 KRH93492.1 - 4.1e-13 49.1 2.1 7.5e-13 48.2 1.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF4131 PF13567.1 KRH93493.1 - 9 5.6 7.6 9.8 5.5 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PCI PF01399.22 KRH93494.1 - 1.4e-12 47.8 1.4 1.4e-12 47.8 0.9 2.3 2 1 0 2 2 2 1 PCI domain P-mevalo_kinase PF04275.9 KRH93494.1 - 0.0052 16.4 0.8 0.013 15.2 0.2 1.9 2 0 0 2 2 2 1 Phosphomevalonate kinase RasGEF_N_2 PF14663.1 KRH93494.1 - 0.022 14.6 2.8 0.037 13.9 0.5 2.4 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain rve_3 PF13683.1 KRH93495.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 KRH93496.1 - 0.018 14.4 0.2 0.026 13.8 0.1 1.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CheR PF01739.13 KRH93496.1 - 0.064 12.5 0.4 0.09 12.0 0.3 1.3 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain PPPI_inhib PF14895.1 KRH93500.1 - 0.18 10.5 1.6 0.23 10.1 1.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor SET PF00856.23 KRH93501.1 - 3.1e-24 86.1 3.2 6.3e-23 81.8 0.1 3.4 2 1 0 2 2 2 1 SET domain Flu_C_NS1 PF03506.8 KRH93501.1 - 2.8 7.6 7.3 14 5.3 5.1 2.1 1 1 0 1 1 1 0 Influenza C non-structural protein (NS1) Daxx PF03344.10 KRH93502.1 - 7.1 4.9 35.2 13 4.0 24.4 1.5 1 0 0 1 1 1 0 Daxx Family DDE_3 PF13358.1 KRH93503.1 - 9.9e-05 22.1 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA-synt_2 PF00152.15 KRH93505.1 - 2.5e-26 92.2 0.2 4.5e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KRH93505.1 - 3.4e-12 46.0 0.7 5.8e-12 45.2 0.5 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mnd1 PF03962.10 KRH93506.1 - 1.7e-34 119.1 5.0 2.2e-34 118.7 3.4 1.1 1 0 0 1 1 1 1 Mnd1 family HAP2-GCS1 PF10699.4 KRH93506.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Male gamete fusion factor AbiH PF14253.1 KRH93506.1 - 0.012 15.2 10.6 0.014 14.9 7.4 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH TBPIP PF07106.8 KRH93506.1 - 0.018 14.5 9.5 0.053 13.0 6.5 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-ZPR1 PF03367.8 KRH93506.1 - 0.022 13.9 1.7 0.03 13.4 0.9 1.4 1 1 0 1 1 1 0 ZPR1 zinc-finger domain BDV_P24 PF06595.6 KRH93506.1 - 0.1 12.3 0.8 0.77 9.4 0.1 2.1 1 1 1 2 2 2 0 Borna disease virus P24 protein Glyco_hydro_20b PF02838.10 KRH93506.1 - 0.1 13.1 0.8 0.16 12.5 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DivIC PF04977.10 KRH93506.1 - 0.43 10.1 7.6 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KRH93506.1 - 4.7 6.7 8.1 8.4 5.9 5.6 1.4 1 0 0 1 1 1 0 IncA protein UAA PF08449.6 KRH93507.1 - 0.00052 19.0 33.5 0.00072 18.5 23.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KRH93507.1 - 0.00059 19.8 14.1 0.00059 19.8 9.7 3.4 2 1 1 3 3 3 1 EamA-like transporter family Clathrin_propel PF01394.15 KRH93507.1 - 0.074 13.3 0.6 7.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Clathrin propeller repeat rve PF00665.21 KRH93508.1 - 1.6e-23 83.1 0.1 6.7e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH93508.1 - 2.5e-21 76.0 0.3 7.7e-21 74.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH93508.1 - 2.3e-09 37.0 0.2 9.5e-09 35.0 0.1 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_Tnp_IS240 PF13610.1 KRH93508.1 - 0.0079 16.1 0.3 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 DDE domain Asp_protease PF09668.5 KRH93508.1 - 0.018 14.5 0.0 0.052 13.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.1 KRH93508.1 - 0.077 13.4 0.1 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease DUF3970 PF13113.1 KRH93510.1 - 0.36 10.5 3.6 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) gag-asp_proteas PF13975.1 KRH93511.1 - 7.9e-07 28.8 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KRH93511.1 - 1.9e-06 28.2 0.1 4.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93511.1 - 0.00019 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93511.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 KRH93511.1 - 0.044 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve_3 PF13683.1 KRH93512.1 - 1.5e-05 24.4 0.1 0.00015 21.2 0.0 2.3 2 1 1 3 3 3 1 Integrase core domain rve PF00665.21 KRH93512.1 - 0.001 19.1 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Coatomer_WDAD PF04053.9 KRH93513.1 - 2.1e-05 23.5 9.1 0.00098 18.0 2.3 2.2 1 1 1 2 2 2 2 Coatomer WD associated region FliD_N PF02465.13 KRH93514.1 - 0.013 15.8 2.6 0.013 15.8 1.8 3.1 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ACI44 PF15270.1 KRH93515.1 - 0.047 13.6 1.2 0.047 13.6 0.8 2.2 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Chordopox_L2 PF05803.7 KRH93516.1 - 1.4 8.5 4.8 0.23 11.1 0.5 1.7 2 0 0 2 2 2 0 Chordopoxvirus L2 protein rve PF00665.21 KRH93518.1 - 0.057 13.5 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain Crinivirus_P26 PF07416.6 KRH93521.1 - 0.021 14.3 0.3 0.029 13.8 0.2 1.2 1 0 0 1 1 1 0 Crinivirus P26 protein NOG1 PF06858.9 KRH93523.1 - 4.6e-22 77.6 0.1 1.4e-21 76.1 0.1 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KRH93523.1 - 5e-14 52.2 0.0 1.6e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.6 KRH93523.1 - 3.1e-10 39.5 5.4 8e-10 38.2 3.8 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 KRH93523.1 - 5.7e-08 32.1 0.3 2.5e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KRH93523.1 - 0.00044 19.4 0.1 0.036 13.2 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Lip_prot_lig_C PF10437.4 KRH93523.1 - 0.0037 16.8 0.8 0.0092 15.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus Dynamin_N PF00350.18 KRH93523.1 - 0.86 9.4 7.6 0.88 9.3 0.0 3.5 2 2 1 3 3 3 0 Dynamin family Glyco_hydro_19 PF00182.14 KRH93526.1 - 0.049 13.2 0.3 1.3 8.6 0.0 2.5 2 1 1 3 3 3 0 Chitinase class I TetR_C_8 PF14278.1 KRH93526.1 - 0.16 12.3 0.3 0.16 12.3 0.2 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Sdh5 PF03937.11 KRH93527.1 - 0.098 12.3 0.8 1.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase Ribosomal_L1 PF00687.16 KRH93529.1 - 6.9e-22 77.8 4.2 8.4e-22 77.5 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Adeno_hexon_C PF03678.9 KRH93534.1 - 0.089 12.2 0.3 0.096 12.1 0.2 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain AAA PF00004.24 KRH93535.1 - 5.3e-98 324.3 0.2 5.4e-49 165.7 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KRH93535.1 - 2.5e-14 53.5 0.1 1.7e-05 24.8 0.0 3.7 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KRH93535.1 - 2.6e-14 52.8 0.0 1.7e-06 27.2 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KRH93535.1 - 1.2e-13 51.3 2.2 3.1e-05 24.1 0.2 5.0 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KRH93535.1 - 4.8e-12 45.8 0.0 5.8e-05 22.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KRH93535.1 - 5.3e-11 43.3 0.7 0.00048 20.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KRH93535.1 - 8.4e-11 41.7 0.3 0.00017 21.3 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KRH93535.1 - 1.9e-10 41.0 0.1 0.00083 19.3 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 KRH93535.1 - 9.4e-10 38.5 0.0 0.00046 20.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KRH93535.1 - 4.1e-09 36.1 0.9 0.0031 16.9 0.0 3.8 3 1 1 4 4 4 2 IstB-like ATP binding protein AAA_25 PF13481.1 KRH93535.1 - 6.7e-09 35.4 6.1 0.11 11.8 0.0 4.6 3 2 1 5 5 4 3 AAA domain TIP49 PF06068.8 KRH93535.1 - 1.1e-08 34.2 0.0 0.0016 17.2 0.0 2.9 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KRH93535.1 - 1.1e-08 35.1 0.0 0.0016 18.5 0.0 3.7 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.1 KRH93535.1 - 3.2e-08 33.9 3.0 0.0029 17.9 0.0 3.6 3 0 0 3 3 2 2 AAA domain KaiC PF06745.8 KRH93535.1 - 1.2e-07 31.1 1.0 0.33 10.0 0.0 3.7 2 1 1 3 3 3 3 KaiC Mg_chelatase PF01078.16 KRH93535.1 - 1.2e-07 31.1 0.2 0.0077 15.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KRH93535.1 - 3.2e-07 29.6 0.0 0.012 14.7 0.0 2.9 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KRH93535.1 - 6.5e-07 29.0 1.1 0.014 15.1 0.3 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 KRH93535.1 - 1.3e-06 28.4 0.0 0.058 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KRH93535.1 - 1.5e-06 28.1 0.6 0.004 17.0 0.0 3.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CDC48_N PF02359.13 KRH93535.1 - 2.8e-06 27.1 0.0 9.2e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 KRH93535.1 - 3.4e-06 27.4 0.4 0.18 12.0 0.0 3.7 3 0 0 3 3 3 2 ABC transporter Parvo_NS1 PF01057.12 KRH93535.1 - 4.1e-06 25.8 0.1 0.026 13.3 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KRH93535.1 - 4.4e-06 26.7 0.0 0.19 11.7 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KRH93535.1 - 4.2e-05 23.3 2.8 0.92 9.1 0.0 4.7 3 2 2 5 5 4 2 Archaeal ATPase NACHT PF05729.7 KRH93535.1 - 4.4e-05 23.2 0.1 0.54 9.8 0.0 3.5 4 0 0 4 4 3 1 NACHT domain AAA_24 PF13479.1 KRH93535.1 - 0.00013 21.6 0.0 0.58 9.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 KRH93535.1 - 0.00014 21.1 0.1 0.56 9.4 0.0 2.9 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 KRH93535.1 - 0.00027 20.5 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KRH93535.1 - 0.00033 20.4 0.4 1.3 8.7 0.0 4.3 3 1 1 4 4 4 1 NTPase Vps4_C PF09336.5 KRH93535.1 - 0.00042 20.1 0.6 0.0046 16.8 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 KRH93535.1 - 0.00047 19.7 0.0 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 KRH93535.1 - 0.00052 19.5 0.0 0.42 10.0 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 KRH93535.1 - 0.00063 19.2 0.0 0.76 9.2 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 KRH93535.1 - 0.0012 17.7 0.0 0.94 8.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Bac_DnaA PF00308.13 KRH93535.1 - 0.0012 18.5 0.1 1 8.9 0.0 3.1 3 1 0 3 3 2 1 Bacterial dnaA protein Cytidylate_kin2 PF13189.1 KRH93535.1 - 0.0034 17.3 0.6 0.38 10.6 0.0 3.0 3 0 0 3 3 2 1 Cytidylate kinase-like family DUF2075 PF09848.4 KRH93535.1 - 0.0045 16.0 3.2 0.58 9.0 0.0 3.1 4 0 0 4 4 3 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KRH93535.1 - 0.0097 15.3 0.3 6.6 6.0 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain AAA_11 PF13086.1 KRH93535.1 - 0.013 15.1 6.1 0.52 9.8 0.0 3.3 3 2 0 3 3 2 0 AAA domain SKI PF01202.17 KRH93535.1 - 0.014 15.2 0.0 2.7 7.8 0.0 3.0 2 0 0 2 2 2 0 Shikimate kinase CDC48_2 PF02933.12 KRH93535.1 - 0.021 14.4 0.2 0.09 12.4 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 UPF0079 PF02367.12 KRH93535.1 - 0.021 14.4 0.1 9.1 5.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KRH93535.1 - 0.041 13.3 0.0 11 5.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KRH93535.1 - 0.061 12.8 0.0 13 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 KRH93535.1 - 0.072 12.2 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DEAD PF00270.24 KRH93537.1 - 3.3e-25 88.5 0.8 1.7e-24 86.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93537.1 - 7.3e-12 44.9 0.6 2.4e-11 43.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KRH93537.1 - 0.025 14.5 0.8 1.7 8.5 0.0 2.9 2 1 1 3 3 3 0 Helicase C-terminal domain DEAD PF00270.24 KRH93538.1 - 2.3e-20 72.7 0.5 1.2e-19 70.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93538.1 - 2.6e-08 33.5 0.0 6.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KRH93538.1 - 3.2e-08 33.6 0.1 2.8e-06 27.3 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KRH93538.1 - 0.00036 20.6 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KRH93538.1 - 0.00057 19.1 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 KRH93538.1 - 0.0016 17.9 0.0 0.013 14.9 0.0 2.5 4 1 0 4 4 4 1 IstB-like ATP binding protein T2SE PF00437.15 KRH93538.1 - 0.014 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KRH93538.1 - 0.092 12.9 0.4 2.7 8.2 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KRH93539.1 - 7.7e-25 87.7 0.1 1.4e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KRH93539.1 - 1.6e-07 30.8 0.6 5e-07 29.1 0.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KRH93539.1 - 9.2e-07 29.1 5.1 9.2e-07 29.1 3.6 4.1 2 2 1 4 4 4 1 AAA domain AAA_22 PF13401.1 KRH93539.1 - 5.2e-06 26.6 0.1 1.2e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH93539.1 - 2.1e-05 24.5 0.0 4.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KRH93539.1 - 0.00029 20.0 0.1 0.00066 18.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KRH93539.1 - 0.00034 21.4 0.1 0.0012 19.6 0.0 2.1 2 1 1 3 3 1 1 AAA domain AAA_23 PF13476.1 KRH93539.1 - 0.00038 20.8 5.6 0.0015 18.8 3.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KRH93539.1 - 0.0004 19.8 0.2 0.0019 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KRH93539.1 - 0.00075 19.3 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.1 KRH93539.1 - 0.00075 18.9 0.3 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KRH93539.1 - 0.00076 19.3 0.0 0.013 15.3 0.0 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 KRH93539.1 - 0.0018 17.2 0.1 0.003 16.5 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 KRH93539.1 - 0.0039 16.8 0.3 0.0067 16.0 0.2 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 KRH93539.1 - 0.0051 16.5 0.3 0.68 9.6 0.0 2.4 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 KRH93539.1 - 0.0053 16.6 0.6 0.018 14.9 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KRH93539.1 - 0.0071 16.0 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KRH93539.1 - 0.0095 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KRH93539.1 - 0.015 14.7 0.2 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KRH93539.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KRH93539.1 - 0.018 14.4 0.5 0.031 13.7 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KRH93539.1 - 0.031 14.1 0.2 0.057 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KRH93539.1 - 0.04 14.0 0.3 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KRH93539.1 - 0.041 13.5 0.1 0.094 12.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KRH93539.1 - 0.066 12.0 0.1 0.14 10.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 KRH93539.1 - 0.099 12.8 1.1 0.85 9.8 0.8 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KRH93539.1 - 0.11 12.4 0.6 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 KRH93539.1 - 0.13 10.8 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class NTPase_P4 PF11602.3 KRH93539.1 - 0.19 10.6 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 UPF0542 PF15086.1 KRH93539.1 - 0.3 10.8 7.9 8.2 6.2 0.2 4.2 4 0 0 4 4 3 0 Uncharacterised protein family UPF0542 AAA_30 PF13604.1 KRH93539.1 - 0.31 10.5 0.1 0.58 9.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF1212 PF06738.7 KRH93539.1 - 1.1 8.7 5.6 2.6 7.4 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF87 PF01935.12 KRH93539.1 - 1.2 8.8 6.5 3.8 7.2 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 KRH93540.1 - 1.2e-28 100.2 0.1 1.5e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KRH93540.1 - 0.00057 19.8 0.1 0.0015 18.4 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KRH93540.1 - 0.0038 17.2 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KRH93540.1 - 0.0046 16.4 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KRH93540.1 - 0.0052 17.6 0.9 0.032 15.0 0.6 2.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KRH93540.1 - 0.013 14.9 0.2 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KRH93540.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KRH93540.1 - 0.025 14.2 0.0 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 KRH93540.1 - 0.046 13.8 0.0 0.2 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KRH93540.1 - 0.05 13.5 4.5 0.064 13.1 0.2 2.8 1 1 0 2 2 2 0 AAA domain Docking PF08990.6 KRH93540.1 - 0.064 12.5 0.6 0.15 11.3 0.4 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking AAA_18 PF13238.1 KRH93540.1 - 0.084 13.1 2.0 0.24 11.6 0.3 2.5 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KRH93540.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KRH93540.1 - 0.18 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RRM_1 PF00076.17 KRH93541.1 - 2.1e-07 30.4 0.0 3.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH93541.1 - 0.00041 20.2 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH93541.1 - 0.00068 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pentapeptide_4 PF13599.1 KRH93542.1 - 4.4e-13 48.8 4.1 7.3e-08 32.1 0.1 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) GCD14 PF08704.5 KRH93542.1 - 3.3 7.1 9.2 0.52 9.7 3.8 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Pyr_redox_dim PF02852.17 KRH93543.1 - 1e-20 73.7 0.0 3.4e-20 72.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KRH93543.1 - 6.9e-20 71.7 0.0 6.3e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KRH93543.1 - 3.6e-14 52.9 0.9 2.6e-13 50.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KRH93543.1 - 0.00018 20.5 0.0 0.00034 19.6 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KRH93543.1 - 0.0035 16.9 0.0 0.058 12.9 0.0 2.7 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KRH93543.1 - 0.015 13.7 0.1 0.35 9.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein UPF0147 PF03685.8 KRH93543.1 - 1.2 8.9 4.8 22 4.9 0.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) Na_H_Exchanger PF00999.16 KRH93546.1 - 3e-42 144.5 34.1 3.8e-42 144.1 23.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cytochrome-c551 PF10643.4 KRH93546.1 - 0.85 8.8 6.3 0.16 11.2 1.5 1.9 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 cNMP_binding PF00027.24 KRH93548.1 - 1.6e-10 40.6 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LicD PF04991.8 KRH93548.1 - 2.8 7.9 6.3 6.2 6.8 4.3 1.7 1 1 0 1 1 1 0 LicD family Nup54 PF13874.1 KRH93549.1 - 2.5e-07 30.4 1.3 4.1e-07 29.7 0.9 1.4 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Matrilin_ccoil PF10393.4 KRH93549.1 - 0.099 12.0 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HAD_2 PF13419.1 KRH93551.1 - 1.4e-05 25.4 0.1 1.4e-05 25.4 0.1 2.3 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase APG6 PF04111.7 KRH93551.1 - 5.3 5.9 39.9 1.4 7.9 8.8 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF902 PF06001.8 KRH93557.1 - 0.041 14.0 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) XRN_N PF03159.13 KRH93558.1 - 1.1e-76 257.4 1.5 1.4e-76 257.0 0.2 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Wyosine_form PF08608.7 KRH93559.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Wyosine base formation Zip PF02535.17 KRH93561.1 - 1.4e-07 30.8 2.9 1.4e-07 30.8 2.0 2.0 1 1 1 2 2 2 1 ZIP Zinc transporter DUF2985 PF11204.3 KRH93561.1 - 0.0062 16.2 0.1 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2985) 7TM-7TMR_HD PF07698.6 KRH93561.1 - 0.96 8.8 5.6 1.3 8.4 3.9 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF2946 PF11162.3 KRH93561.1 - 8 6.6 10.2 14 5.9 7.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) DUF21 PF01595.15 KRH93562.1 - 0.025 13.8 0.1 0.025 13.8 0.1 2.8 2 1 1 4 4 4 0 Domain of unknown function DUF21 MAGP PF05507.6 KRH93562.1 - 0.16 11.8 0.7 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) EF-hand_10 PF14788.1 KRH93564.1 - 0.0045 16.6 1.2 0.69 9.6 0.0 2.6 2 0 0 2 2 2 2 EF hand PTPS PF01242.14 KRH93564.1 - 0.022 14.4 0.6 0.036 13.7 0.4 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase OS-D PF03392.8 KRH93564.1 - 0.033 14.1 2.0 0.08 12.9 1.4 1.7 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Shikimate_DH PF01488.15 KRH93564.1 - 0.13 12.3 1.5 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF740 PF05340.7 KRH93564.1 - 0.14 10.5 6.2 0.15 10.3 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF1289 PF06945.8 KRH93564.1 - 0.66 9.4 2.3 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) rve PF00665.21 KRH93566.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain PRANC PF09372.5 KRH93566.1 - 0.059 13.3 0.2 0.1 12.5 0.1 1.5 1 1 0 1 1 1 0 PRANC domain Kazal_1 PF00050.16 KRH93566.1 - 0.22 11.5 0.5 0.22 11.5 0.3 1.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain RVT_1 PF00078.22 KRH93568.1 - 1.5e-09 37.5 0.3 1.9e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF777 PF05606.6 KRH93568.1 - 0.28 10.3 4.3 0.44 9.6 3.0 1.3 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Asp_protease_2 PF13650.1 KRH93569.1 - 4e-05 24.0 0.0 9.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 KRH93569.1 - 0.00026 20.3 0.7 0.00056 19.2 0.2 1.8 1 1 1 2 2 2 1 Ty3 transposon peptidase RVP PF00077.15 KRH93569.1 - 0.043 13.7 2.6 0.27 11.1 0.0 2.7 1 1 0 2 2 2 0 Retroviral aspartyl protease RVP PF00077.15 KRH93572.1 - 2.8e-11 43.1 0.1 5e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93572.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KRH93572.1 - 0.0096 16.3 0.1 0.016 15.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.10 KRH93572.1 - 0.012 15.2 0.3 0.016 14.8 0.2 1.4 1 1 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Abhydrolase_1 PF00561.15 KRH93574.1 - 0.0033 17.0 0.0 0.0039 16.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KRH93574.1 - 0.027 14.3 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_2 PF07719.12 KRH93575.1 - 0.0015 18.2 1.8 4.2 7.5 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KRH93575.1 - 0.005 17.4 0.0 1.6 9.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KRH93575.1 - 0.0058 16.5 2.0 2.8 7.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2686 PF10887.3 KRH93575.1 - 0.033 12.9 0.2 0.076 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2686) TPR_11 PF13414.1 KRH93575.1 - 0.038 13.6 4.3 1.8 8.3 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.1 KRH93575.1 - 0.21 11.4 1.2 2.6 8.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KRH93575.1 - 0.28 10.8 1.9 16 5.2 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KRH93575.1 - 0.38 10.6 8.4 2.4 8.1 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Cupin_8 PF13621.1 KRH93575.1 - 1.8 8.0 8.5 0.16 11.4 1.2 2.0 2 0 0 2 2 2 0 Cupin-like domain TLC PF03219.9 KRH93577.1 - 2.4e-53 181.3 32.5 3.8e-53 180.6 22.6 1.2 1 1 0 1 1 1 1 TLC ATP/ADP transporter HTH_Tnp_Tc3_2 PF01498.13 KRH93578.1 - 0.018 15.0 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Transposase ABC_tran PF00005.22 KRH93579.1 - 1.9e-14 54.1 0.2 1.9e-14 54.1 0.1 3.4 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.18 KRH93579.1 - 2.2e-10 40.4 4.0 2.2e-10 40.4 2.8 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KRH93579.1 - 0.0069 15.6 0.8 0.0069 15.6 0.6 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KRH93579.1 - 0.011 16.5 0.0 0.057 14.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KRH93579.1 - 0.027 14.3 0.1 0.027 14.3 0.0 3.6 4 0 0 4 4 4 0 Dynamin family Miro PF08477.8 KRH93579.1 - 0.05 14.0 0.0 0.05 14.0 0.0 2.8 4 0 0 4 4 4 0 Miro-like protein AAA_29 PF13555.1 KRH93579.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KRH93579.1 - 0.069 13.2 0.5 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KRH93579.1 - 0.075 12.9 0.0 9.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KRH93579.1 - 0.2 11.2 0.2 23 4.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.19 KRH93580.1 - 8.1e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KRH93580.1 - 0.021 15.0 0.8 0.034 14.3 0.6 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KRH93580.1 - 0.025 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BRX_N PF13713.1 KRH93580.1 - 0.036 13.5 1.2 6 6.4 0.2 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain MOZ_SAS PF01853.13 KRH93580.1 - 0.046 12.9 0.3 0.046 12.9 0.2 1.6 2 0 0 2 2 2 0 MOZ/SAS family DEAD PF00270.24 KRH93581.1 - 7e-42 142.7 0.0 1.5e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH93581.1 - 3.2e-26 90.9 0.2 8.4e-26 89.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KRH93581.1 - 0.0011 18.7 0.0 0.0038 17.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KRH93581.1 - 0.038 13.0 0.6 0.12 11.4 0.0 2.0 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 KRH93581.1 - 0.081 13.0 0.0 0.33 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain Ribosomal_S13_N PF08069.7 KRH93583.1 - 2.6e-19 68.8 0.1 4.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KRH93583.1 - 1.9e-12 46.7 1.9 2.8e-12 46.2 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.3 KRH93583.1 - 0.0025 17.9 0.1 0.0039 17.3 0.0 1.4 1 1 0 1 1 1 1 Heat induced stress protein YflT DUF3860 PF12976.2 KRH93583.1 - 0.11 12.3 0.5 0.43 10.4 0.1 1.9 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) DUF3050 PF11251.3 KRH93583.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3050) Pap_E4 PF02711.9 KRH93584.1 - 4.9 8.0 7.7 1.3 9.8 2.7 1.9 1 1 1 2 2 2 0 E4 protein dsDNA_bind PF01984.15 KRH93585.1 - 2.2e-15 56.5 0.0 2.5e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain zf-CHY PF05495.7 KRH93586.1 - 3.6e-12 46.2 32.1 3.6e-12 46.2 22.2 4.6 1 1 2 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 KRH93586.1 - 7.6e-09 35.2 5.2 7.6e-09 35.2 3.6 4.4 4 2 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 KRH93586.1 - 1e-07 31.5 4.9 1e-07 31.5 3.4 6.2 3 1 2 5 5 5 1 zinc-RING finger domain zinc_ribbon_6 PF14599.1 KRH93586.1 - 1.5e-07 31.1 7.7 1.5e-07 31.1 5.3 4.3 4 1 1 5 5 5 1 Zinc-ribbon zf-C3HC4_2 PF13923.1 KRH93586.1 - 1.1e-06 28.5 7.4 1.1e-06 28.5 5.1 5.4 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH93586.1 - 0.00015 21.3 7.1 0.00015 21.3 4.9 5.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KRH93586.1 - 0.004 17.2 2.8 0.004 17.2 1.9 4.4 3 1 1 4 4 4 1 RING-H2 zinc finger Rubis-subs-bind PF09273.6 KRH93586.1 - 0.13 12.1 1.9 0.88 9.4 1.5 2.0 1 1 1 2 2 2 0 Rubisco LSMT substrate-binding MAGE PF01454.14 KRH93587.1 - 0.017 14.4 5.7 0.14 11.4 4.0 2.2 1 1 0 1 1 1 0 MAGE family TMEM237 PF15383.1 KRH93587.1 - 0.038 13.1 0.8 0.064 12.3 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 TMF_DNA_bd PF12329.3 KRH93588.1 - 0.00017 21.3 14.8 0.00017 21.3 10.2 10.3 9 3 2 11 11 11 1 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 KRH93588.1 - 0.0012 19.0 4.2 0.0012 19.0 2.9 7.0 5 1 0 6 6 6 3 Nucleopolyhedrovirus P10 protein EF-hand_6 PF13405.1 KRH93589.1 - 2.1e-05 24.0 3.5 0.18 11.7 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KRH93589.1 - 2.3e-05 23.3 2.2 0.63 9.4 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KRH93589.1 - 0.0004 19.9 2.4 0.1 12.2 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair Terminase_1 PF03354.10 KRH93589.1 - 0.0078 14.6 0.3 0.01 14.3 0.2 1.1 1 0 0 1 1 1 1 Phage Terminase EFhand_Ca_insen PF08726.5 KRH93589.1 - 0.026 14.5 0.7 0.026 14.5 0.5 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_7 PF13499.1 KRH93589.1 - 0.034 14.2 6.2 4.3 7.5 0.0 3.4 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 KRH93589.1 - 0.041 13.2 2.7 1.1 8.7 0.1 3.0 3 0 0 3 3 3 0 EF hand Sen15 PF09631.5 KRH93589.1 - 0.11 12.7 0.6 0.5 10.6 0.2 2.2 1 1 1 2 2 2 0 Sen15 protein GSHPx PF00255.14 KRH93590.1 - 1.1e-20 73.0 2.2 8.8e-16 57.2 0.1 2.3 2 0 0 2 2 2 2 Glutathione peroxidase INT_SG_DDX_CT_C PF15300.1 KRH93590.1 - 0.026 13.9 0.2 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus VGCC_alpha2 PF08473.6 KRH93592.1 - 0.045 13.5 0.0 0.053 13.2 0.0 1.0 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Sel1 PF08238.7 KRH93593.1 - 5.7e-21 74.4 25.3 7.3e-06 26.4 1.7 6.6 7 0 0 7 7 7 5 Sel1 repeat Fcf1 PF04900.7 KRH93594.1 - 1.1e-31 108.8 0.8 1.9e-31 108.1 0.3 1.6 2 0 0 2 2 2 1 Fcf1 GCV_T PF01571.16 KRH93594.1 - 0.048 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Glycolytic PF00274.14 KRH93595.1 - 6.8e-91 304.2 0.0 9.4e-91 303.7 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I C8 PF08742.6 KRH93595.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 C8 domain DUF3393 PF11873.3 KRH93597.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Rad52_Rad22 PF04098.10 KRH93598.1 - 7.2e-52 175.2 1.0 9.3e-52 174.8 0.7 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ribonuc_L-PSP PF01042.16 KRH93598.1 - 0.062 13.0 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP ATC_hydrolase PF14196.1 KRH93598.1 - 0.1 12.9 0.7 0.16 12.3 0.5 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DALR_2 PF09190.6 KRH93598.1 - 0.8 10.0 7.5 5.9 7.2 0.2 2.9 3 1 0 3 3 3 0 DALR domain bZIP_1 PF00170.16 KRH93600.1 - 0.025 14.5 1.1 0.025 14.5 0.8 10.9 9 2 2 11 11 11 0 bZIP transcription factor Tropomyosin_1 PF12718.2 KRH93600.1 - 0.6 9.9 103.9 0.31 10.8 11.1 6.1 1 1 4 5 5 5 0 Tropomyosin like Spc7 PF08317.6 KRH93600.1 - 1.3 7.6 102.1 0.0052 15.4 23.2 5.4 1 1 3 5 5 5 0 Spc7 kinetochore protein HrpB7 PF09486.5 KRH93600.1 - 2 8.3 22.8 0.51 10.2 2.7 4.0 4 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.20 KRH93601.1 - 5.3e-09 35.6 1.1 5.3e-09 35.6 0.8 2.2 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 KRH93601.1 - 3.2e-08 33.6 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KRH93601.1 - 2.9e-07 30.0 6.9 7.5e-05 22.1 0.1 2.3 1 1 1 2 2 2 2 RIO1 family Kdo PF06293.9 KRH93601.1 - 6.5e-05 22.0 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KRH93601.1 - 0.0041 16.2 1.2 0.0076 15.3 0.5 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase ETRAMP PF09716.5 KRH93602.1 - 0.00078 19.3 2.5 0.00078 19.3 1.7 2.7 4 0 0 4 4 4 1 Malarial early transcribed membrane protein (ETRAMP) Metallophos PF00149.23 KRH93604.1 - 1.8e-31 109.0 0.2 2.4e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KRH93604.1 - 0.00053 19.8 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PAN_3 PF08277.7 KRH93604.1 - 0.012 15.2 1.1 0.033 13.8 0.4 2.0 2 0 0 2 2 2 0 PAN-like domain GSIII_N PF12437.3 KRH93606.1 - 1.5e-49 167.5 0.0 3.1e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 KRH93606.1 - 6e-38 130.4 0.0 1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Peptidase_M16_C PF05193.16 KRH93607.1 - 0.0024 17.5 0.8 0.22 11.2 0.0 2.9 3 1 0 3 3 3 2 Peptidase M16 inactive domain IL6 PF00489.12 KRH93607.1 - 0.022 14.3 0.0 0.076 12.5 0.0 1.9 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family s48_45 PF07422.8 KRH93610.1 - 0.045 13.8 0.8 0.063 13.3 0.5 1.3 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain DNA_ligase_A_M PF01068.16 KRH93611.1 - 7.2e-42 143.0 3.9 5.1e-40 137.0 2.7 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KRH93611.1 - 4e-39 134.2 2.9 7.4e-39 133.3 2.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KRH93611.1 - 1.4e-22 79.8 0.0 9.1e-22 77.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KRH93611.1 - 0.0018 18.0 2.5 0.018 14.7 0.6 3.1 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain Gtr1_RagA PF04670.7 KRH93611.1 - 0.0026 16.9 1.3 0.0068 15.5 0.9 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DNA_ligase_OB_2 PF14743.1 KRH93611.1 - 0.13 11.9 1.6 1.4 8.6 1.1 2.5 1 1 0 1 1 1 0 DNA ligase OB-like domain GTP_EFTU PF00009.22 KRH93612.1 - 6.3e-42 143.1 0.0 7.5e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KRH93612.1 - 7e-24 83.8 0.1 2e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KRH93612.1 - 1.7e-09 37.6 0.1 6.9e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KRH93612.1 - 0.0017 17.9 0.1 0.0067 16.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 KRH93612.1 - 0.002 17.3 0.5 0.49 9.5 0.0 2.7 3 1 0 3 3 3 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KRH93612.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KRH93612.1 - 0.026 15.0 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein DUF2481 PF10654.4 KRH93614.1 - 0.27 10.9 5.5 4 7.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2481) DDT PF02791.12 KRH93615.1 - 0.024 14.4 0.1 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 DDT domain M20_dimer PF07687.9 KRH93615.1 - 0.043 13.5 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase dimerisation domain LAGLIDADG_1 PF00961.14 KRH93615.1 - 0.86 10.1 5.7 0.72 10.4 0.4 2.1 2 0 0 2 2 2 0 LAGLIDADG endonuclease Peptidase_C48 PF02902.14 KRH93617.1 - 1.6e-11 44.2 0.4 2.2e-11 43.8 0.3 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KRH93617.1 - 4.4e-06 25.4 3.8 1.5e-05 23.6 0.2 2.0 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase rve PF00665.21 KRH93619.1 - 0.052 13.6 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DUF3753 PF12575.3 KRH93620.1 - 0.051 13.3 1.7 0.12 12.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF106 PF01956.11 KRH93620.1 - 0.096 12.2 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Orbi_NS3 PF01616.11 KRH93620.1 - 0.13 11.1 1.1 0.63 8.9 0.8 1.9 2 0 0 2 2 2 0 Orbivirus NS3 DUF740 PF05340.7 KRH93620.1 - 0.21 9.9 2.4 0.26 9.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) L1R_F9L PF02442.12 KRH93620.1 - 0.74 9.2 5.7 2.7 7.4 0.1 2.2 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DUF912 PF06024.7 KRH93620.1 - 3.4 7.7 6.1 10 6.2 4.3 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-Di19 PF05605.7 KRH93621.1 - 0.054 13.6 1.7 0.12 12.5 1.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KRH93621.1 - 0.15 12.4 1.4 0.4 11.1 1.0 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KRH93621.1 - 0.23 11.8 1.8 0.67 10.4 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Nuf2 PF03800.9 KRH93623.1 - 2.3e-13 50.3 1.3 1.8e-10 40.9 0.8 4.0 3 2 1 4 4 4 2 Nuf2 family DUF3154 PF11351.3 KRH93623.1 - 1.2 8.9 4.3 1.2 8.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Reo_sigmaC PF04582.7 KRH93623.1 - 1.3 8.0 16.8 0.47 9.5 1.2 3.0 1 1 4 5 5 5 0 Reovirus sigma C capsid protein TPR_11 PF13414.1 KRH93624.1 - 1.7e-16 59.6 4.4 2.9e-13 49.2 2.4 3.7 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.1 KRH93624.1 - 1e-10 41.4 3.9 5.2e-10 39.1 1.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KRH93624.1 - 2.8e-07 29.9 6.6 0.00086 19.0 0.3 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KRH93624.1 - 0.0013 18.2 0.9 0.0013 18.2 0.6 5.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KRH93624.1 - 0.003 17.6 3.1 0.074 13.2 0.0 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KRH93624.1 - 0.0038 17.8 0.0 0.012 16.2 0.0 1.7 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KRH93624.1 - 0.0071 16.0 2.5 0.0071 16.0 1.7 5.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KRH93624.1 - 0.0084 16.0 0.0 3.7 7.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KRH93624.1 - 0.0091 16.3 0.6 2.1 8.7 0.2 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KRH93624.1 - 0.045 13.5 0.8 0.76 9.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KRH93624.1 - 0.064 13.0 1.7 0.21 11.4 0.6 2.3 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region SHNi-TPR PF10516.4 KRH93624.1 - 0.11 11.8 1.5 0.16 11.2 0.2 2.0 2 0 0 2 2 2 0 SHNi-TPR Apc3 PF12895.2 KRH93624.1 - 0.23 11.6 8.3 0.12 12.5 2.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BRCA2 PF00634.13 KRH93624.1 - 9.5 5.6 9.3 25 4.2 0.1 4.1 4 0 0 4 4 4 0 BRCA2 repeat Cpn60_TCP1 PF00118.19 KRH93625.1 - 2e-101 340.0 20.9 2.3e-101 339.8 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2335 PF10097.4 KRH93626.1 - 9.8 5.8 10.2 0.23 11.1 1.2 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) RLL PF10036.4 KRH93629.1 - 0.0029 17.0 3.0 0.0074 15.7 2.0 1.6 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein RVT_1 PF00078.22 KRH93630.1 - 0.00036 19.9 0.1 0.00057 19.3 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4233 PF14017.1 KRH93631.1 - 0.4 10.6 6.0 0.61 10.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) vATP-synt_AC39 PF01992.11 KRH93632.1 - 1.2e-22 80.5 11.1 2.2e-22 79.6 7.7 1.4 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF2605 PF10792.4 KRH93632.1 - 0.058 13.0 0.4 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) SNF2_N PF00176.18 KRH93634.1 - 1.9e-56 191.0 10.1 1.9e-56 191.0 7.0 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KRH93634.1 - 1.4e-16 60.1 0.0 9.3e-16 57.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBINO PF13892.1 KRH93634.1 - 9e-11 41.9 19.2 9e-11 41.9 13.3 4.7 5 1 0 5 5 5 1 DNA-binding domain Ribosomal_L18e PF00828.14 KRH93636.1 - 9.6e-11 42.1 0.3 1.4e-10 41.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF2420 PF10336.4 KRH93638.1 - 0.042 13.4 1.8 0.079 12.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Mis14 PF08641.7 KRH93640.1 - 0.11 12.5 2.3 0.12 12.4 0.2 2.1 1 1 1 2 2 2 0 Kinetochore protein Mis14 like HalX PF08663.5 KRH93640.1 - 0.13 12.3 0.9 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 HalX domain DUF2115 PF09888.4 KRH93640.1 - 0.33 11.0 2.9 0.46 10.5 1.4 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Med2 PF11214.3 KRH93640.1 - 0.63 10.1 12.5 1.3 9.1 7.4 2.3 1 1 1 2 2 2 0 Mediator complex subunit 2 HAD_2 PF13419.1 KRH93641.1 - 5.6e-13 49.4 0.0 1.1e-11 45.2 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KRH93641.1 - 0.0026 17.3 0.2 0.047 13.3 0.1 2.6 1 1 0 1 1 1 1 Acid Phosphatase DnaJ PF00226.26 KRH93642.1 - 1.2e-17 63.3 1.5 2.2e-17 62.5 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KRH93642.1 - 4.8e-11 42.5 16.8 8.8e-11 41.6 11.7 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KRH93642.1 - 1.7e-09 37.4 4.7 8.3e-06 25.6 0.1 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain LMSTEN PF07988.7 KRH93642.1 - 0.018 14.3 2.0 0.041 13.1 1.4 1.5 1 0 0 1 1 1 0 LMSTEN motif FAM92 PF06730.6 KRH93642.1 - 0.035 13.4 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 FAM92 protein Cpn60_TCP1 PF00118.19 KRH93643.1 - 3.6e-112 375.4 21.1 4.4e-112 375.1 14.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EF-hand_6 PF13405.1 KRH93644.1 - 2.8e-05 23.6 0.8 0.00011 21.7 0.5 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KRH93644.1 - 0.00011 22.3 2.1 0.0002 21.4 1.5 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KRH93644.1 - 0.00013 21.0 1.9 0.00033 19.7 0.6 2.3 2 0 0 2 2 2 1 EF hand EF-hand_2 PF09068.6 KRH93644.1 - 0.0032 17.5 0.8 0.034 14.2 0.1 2.1 1 1 1 2 2 2 1 EF hand GTP-bdg_N PF13167.1 KRH93644.1 - 0.0072 16.4 1.1 0.023 14.8 0.1 2.2 2 1 0 2 2 2 1 GTP-binding GTPase N-terminal FliW PF02623.10 KRH93644.1 - 0.01 15.4 1.1 0.01 15.3 0.1 1.5 2 0 0 2 2 2 1 FliW protein EF-hand_5 PF13202.1 KRH93644.1 - 0.021 14.1 0.5 0.021 14.1 0.4 2.2 2 0 0 2 2 2 0 EF hand DUF2660 PF10859.3 KRH93644.1 - 0.026 14.7 3.0 0.49 10.6 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2660) EF-hand_8 PF13833.1 KRH93644.1 - 0.029 13.9 0.7 0.097 12.2 0.2 2.2 2 1 1 3 3 3 0 EF-hand domain pair TFIID_20kDa PF03847.8 KRH93645.1 - 1e-09 38.5 0.7 1.6e-09 37.8 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 KRH93645.1 - 6.6e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KRH93645.1 - 0.00031 20.4 0.1 0.00056 19.6 0.1 1.4 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 KRH93645.1 - 0.0073 16.0 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 KRH93645.1 - 0.011 15.7 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.9 KRH93645.1 - 0.088 12.0 0.2 0.11 11.7 0.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TAFII28 PF04719.9 KRH93645.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region YokU PF14122.1 KRH93646.1 - 0.098 12.3 0.1 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 YokU-like protein KH_1 PF00013.24 KRH93647.1 - 0.022 14.3 0.2 0.022 14.3 0.1 2.1 2 0 0 2 2 2 0 KH domain Septin PF00735.13 KRH93648.1 - 3.7e-45 154.1 5.2 6.4e-45 153.3 3.6 1.4 1 0 0 1 1 1 1 Septin SUFU PF05076.8 KRH93648.1 - 0.043 13.3 0.1 0.48 9.9 0.0 2.4 2 1 0 2 2 2 0 Suppressor of fused protein (SUFU) Homeobox PF00046.24 KRH93649.1 - 1.1e-12 47.3 2.4 2.7e-12 46.1 1.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH93649.1 - 0.00011 21.7 0.1 0.00047 19.7 0.0 2.0 1 0 0 1 1 1 1 Homeobox KN domain FH2 PF02181.18 KRH93650.1 - 6e-22 78.0 16.1 6e-22 78.0 11.1 2.5 3 0 0 3 3 3 2 Formin Homology 2 Domain Bromodomain PF00439.20 KRH93651.1 - 7.9e-27 93.0 1.2 7.9e-27 93.0 0.8 2.4 3 0 0 3 3 3 1 Bromodomain Acetyltransf_7 PF13508.1 KRH93651.1 - 7.9e-09 35.5 0.1 1.7e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KRH93651.1 - 3.1e-06 27.1 0.0 8.2e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KRH93651.1 - 0.072 13.2 0.0 0.42 10.7 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KRH93651.1 - 0.085 12.1 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Arc_PepC PF06819.6 KRH93652.1 - 0.029 14.3 0.1 0.18 11.7 0.0 2.1 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain DNA_pol_B_palm PF14792.1 KRH93652.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase beta palm DUF4428 PF14471.1 KRH93654.1 - 0.0028 17.3 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.8 KRH93654.1 - 0.019 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 ClpX C4-type zinc finger Trehalase PF01204.13 KRH93655.1 - 1.1e-102 344.3 1.8 1.1e-102 344.3 1.3 1.8 1 1 1 2 2 2 1 Trehalase DUF1797 PF08796.5 KRH93655.1 - 0.0062 16.3 0.4 0.082 12.7 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1797) GDE_C PF06202.9 KRH93655.1 - 0.0094 14.6 4.0 0.097 11.3 2.8 2.3 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Linker_histone PF00538.14 KRH93655.1 - 0.15 12.1 1.1 29 4.8 0.0 3.3 3 0 0 3 3 3 0 linker histone H1 and H5 family DDE_Tnp_IS1595 PF12762.2 KRH93656.1 - 3.4e-24 85.4 0.3 3.9e-24 85.1 0.2 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain P35 PF02331.10 KRH93656.1 - 0.011 14.8 1.5 0.016 14.3 1.0 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein DUF3139 PF11337.3 KRH93660.1 - 0.0018 18.5 0.2 0.008 16.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3139) DUF1510 PF07423.6 KRH93660.1 - 0.002 17.5 3.7 0.0022 17.4 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 KRH93660.1 - 0.008 16.0 0.2 0.009 15.9 0.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CoxIIa PF08113.6 KRH93660.1 - 0.012 15.3 2.2 0.017 14.7 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family OSTbeta PF15048.1 KRH93660.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF2371 PF10177.4 KRH93660.1 - 0.052 13.4 0.2 0.085 12.7 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) EphA2_TM PF14575.1 KRH93660.1 - 0.11 12.8 0.6 0.28 11.6 0.4 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 KRH93660.1 - 0.15 11.6 5.1 0.26 10.8 3.5 1.4 1 1 0 1 1 1 0 IncA protein CAF1A PF12253.3 KRH93660.1 - 0.93 9.6 3.4 0.75 9.9 0.1 2.0 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A DDE_Tnp_IS1595 PF12762.2 KRH93661.1 - 4.4e-12 46.0 1.2 5.4e-12 45.7 0.8 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Spike_rec_bind PF09408.5 KRH93661.1 - 0.032 13.7 1.2 0.037 13.5 0.8 1.1 1 0 0 1 1 1 0 Spike receptor binding domain PRO8NT PF08082.6 KRH93662.1 - 0.12 11.9 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain RVP_2 PF08284.6 KRH93663.1 - 1.1e-06 28.5 0.1 1.4e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH93663.1 - 1.3e-05 25.5 0.1 2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93663.1 - 0.00029 20.6 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93663.1 - 0.00058 19.4 0.1 0.00082 18.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93663.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 KRH93664.1 - 6.6e-16 58.3 0.0 8.7e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH93664.1 - 0.09 11.7 0.1 0.15 10.9 0.1 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH93664.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain rve PF00665.21 KRH93665.1 - 8.6e-08 32.3 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain F-actin_cap_A PF01267.12 KRH93666.1 - 0.031 13.3 0.1 0.031 13.3 0.1 1.1 1 0 0 1 1 1 0 F-actin capping protein alpha subunit SEP PF08059.8 KRH93666.1 - 0.038 14.3 0.1 0.07 13.4 0.1 1.5 1 0 0 1 1 1 0 SEP domain zf-CCHC PF00098.18 KRH93667.1 - 6.1e-07 29.0 2.1 6.1e-07 29.0 1.4 2.0 2 0 0 2 2 2 1 Zinc knuckle DUF4482 PF14818.1 KRH93667.1 - 0.036 14.7 3.0 0.065 13.8 0.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) zf-CCHC_4 PF14392.1 KRH93667.1 - 0.063 12.9 4.8 0.1 12.3 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle CorA PF01544.13 KRH93667.1 - 0.064 12.2 0.5 0.1 11.6 0.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 KRH93667.1 - 0.47 10.0 2.4 0.91 9.0 1.6 1.5 1 0 0 1 1 1 0 IncA protein zf-CCHC_6 PF15288.1 KRH93667.1 - 1.4 8.6 4.3 6 6.6 2.2 2.3 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 KRH93668.1 - 1.7e-23 83.1 0.1 2.3e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop PF01798.13 KRH93670.1 - 6.4e-21 74.2 0.1 1.1e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Pox_T4_N PF04491.7 KRH93674.1 - 0.078 12.8 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus DDE_3 PF13358.1 KRH93675.1 - 6.4e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 KRH93675.1 - 8.9e-06 24.9 0.0 0.00045 19.4 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Arg_repressor PF01316.16 KRH93675.1 - 0.00028 20.3 0.5 0.00056 19.4 0.3 1.5 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain rve PF00665.21 KRH93675.1 - 0.038 14.0 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_21 PF13276.1 KRH93675.1 - 0.049 13.6 2.2 0.18 11.8 0.7 2.2 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 KRH93675.1 - 0.15 12.0 1.3 0.39 10.8 0.9 1.7 1 0 0 1 1 1 0 Transposase Acetyltransf_11 PF13720.1 KRH93677.1 - 0.074 13.2 1.4 0.25 11.6 0.4 2.1 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Acetyltransf_7 PF13508.1 KRH93678.1 - 1.5e-12 47.4 0.1 2.4e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KRH93678.1 - 1.3e-11 44.3 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KRH93678.1 - 3.4e-06 26.9 0.0 6.3e-06 26.1 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KRH93678.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KRH93678.1 - 2.5e-05 24.2 0.5 3.3e-05 23.8 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KRH93678.1 - 0.0001 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KRH93678.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KRH93678.1 - 0.007 16.5 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribonuc_red_lgC PF02867.10 KRH93679.1 - 4.9e-198 659.0 0.6 9.4e-198 658.1 0.0 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KRH93679.1 - 3.6e-21 74.7 0.1 9.1e-21 73.4 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KRH93679.1 - 0.00075 19.8 0.0 0.0035 17.7 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain ATG_C PF09333.6 KRH93682.1 - 0.11 12.6 5.4 0.31 11.2 0.7 3.3 3 0 0 3 3 3 0 ATG C terminal domain PTS_IIA PF02255.11 KRH93682.1 - 0.76 9.6 10.7 10 6.0 0.7 3.9 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2611 PF11022.3 KRH93682.1 - 3.2 7.9 7.6 5.5 7.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) LIM_bind PF01803.11 KRH93683.1 - 0.14 11.2 2.0 0.19 10.8 1.4 1.2 1 0 0 1 1 1 0 LIM-domain binding protein TruB_N PF01509.13 KRH93684.1 - 9.5e-19 68.0 1.3 1.4e-12 47.9 0.1 3.1 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 KRH93684.1 - 4.4e-18 64.9 0.3 6.3e-17 61.2 0.2 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.15 KRH93684.1 - 3.7e-15 55.3 0.7 7.4e-15 54.4 0.5 1.5 1 0 0 1 1 1 1 PUA domain DNA_pol_B PF00136.16 KRH93685.1 - 1.7e-75 254.6 10.0 4.4e-75 253.2 7.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B IP_trans PF02121.13 KRH93686.1 - 3.9e-35 121.2 8.2 1.3e-34 119.5 5.7 1.8 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein Ricin_B_lectin PF00652.17 KRH93687.1 - 0.079 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain TSP_1 PF00090.14 KRH93688.1 - 0.13 12.4 1.1 0.17 12.0 0.2 1.6 2 0 0 2 2 2 0 Thrombospondin type 1 domain HTH_Tnp_Tc3_2 PF01498.13 KRH93690.1 - 1.7e-08 34.3 0.7 1.5e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 Transposase HTH_29 PF13551.1 KRH93690.1 - 0.0017 18.4 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 KRH93690.1 - 0.0033 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 KRH93690.1 - 0.053 14.3 0.0 0.096 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MCM PF00493.18 KRH93692.1 - 1.3e-40 139.2 7.5 3.9e-32 111.3 0.1 4.0 4 0 0 4 4 4 3 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 KRH93692.1 - 6e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 KRH93692.1 - 7.8e-05 22.2 0.6 0.00079 18.9 0.4 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 KRH93692.1 - 8e-05 22.5 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KRH93692.1 - 9.8e-05 21.3 0.4 0.00034 19.6 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 KRH93692.1 - 0.00018 20.2 0.1 0.00049 18.8 0.1 1.7 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 KRH93692.1 - 0.00026 20.2 2.2 0.066 12.3 0.2 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KRH93692.1 - 0.0015 18.6 0.5 0.0081 16.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KRH93692.1 - 0.0051 16.3 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_3 PF07726.6 KRH93692.1 - 0.0075 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KRH93692.1 - 0.013 15.2 0.2 0.037 13.7 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KRH93692.1 - 0.016 14.6 0.5 0.032 13.6 0.3 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KRH93692.1 - 0.024 14.2 0.0 0.076 12.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KRH93692.1 - 0.025 14.2 0.6 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KRH93692.1 - 0.03 14.8 3.1 0.056 13.9 0.1 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_5 PF07728.9 KRH93692.1 - 0.046 13.4 0.4 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KRH93692.1 - 0.14 12.9 0.8 0.35 11.7 0.1 2.1 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KRH93692.1 - 0.61 10.3 8.4 0.063 13.5 0.7 3.0 3 1 0 3 3 3 0 ABC transporter DSHCT PF08148.7 KRH93694.1 - 2.2e-27 95.4 0.3 2.2e-27 95.4 0.2 2.2 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.24 KRH93694.1 - 1.3e-22 80.0 0.0 3.2e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KRH93694.1 - 1.6e-06 28.0 0.1 1.6e-06 28.0 0.1 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KRH93694.1 - 4.4e-06 26.4 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.3 KRH93694.1 - 9.6e-06 24.6 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) PhoH PF02562.11 KRH93694.1 - 0.0041 16.3 0.1 0.013 14.7 0.1 1.8 1 1 0 1 1 1 1 PhoH-like protein TFIIB PF00382.14 KRH93695.1 - 5e-31 106.3 0.1 1.4e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KRH93695.1 - 1.8e-12 47.3 9.1 1.3e-10 41.3 6.3 2.4 1 1 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 KRH93695.1 - 0.00013 21.1 0.7 0.00038 19.7 0.5 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 KRH93695.1 - 0.00056 19.4 0.4 0.037 13.5 0.0 2.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cys_rich_CPCC PF14206.1 KRH93695.1 - 0.0087 15.5 0.3 0.02 14.4 0.2 1.6 1 0 0 1 1 1 1 Cysteine-rich CPCC DZR PF12773.2 KRH93695.1 - 0.12 12.2 1.7 0.3 10.9 1.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KRH93695.1 - 0.49 9.6 3.8 2 7.7 2.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain LRR_4 PF12799.2 KRH93696.1 - 1.2e-08 34.3 14.2 0.00016 21.2 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KRH93696.1 - 1.7e-08 33.6 17.4 0.012 15.6 0.1 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 KRH93696.1 - 1.8e-06 27.1 9.8 0.056 13.4 0.1 6.5 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 KRH93696.1 - 9.8e-05 22.0 13.2 0.054 13.2 0.6 4.9 3 3 2 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 KRH93696.1 - 0.00037 20.2 2.9 9.9 6.8 0.0 6.1 6 0 0 6 6 6 1 Leucine rich repeat DUF2893 PF11459.3 KRH93696.1 - 0.021 14.5 0.4 23 4.8 0.1 3.5 3 0 0 3 3 3 0 Protein of unknwon function (DUF2893) FTH PF01827.22 KRH93696.1 - 0.13 11.8 14.0 1.2 8.7 0.4 3.7 3 1 1 4 4 4 0 FTH domain PGI PF00342.14 KRH93697.1 - 7.9e-136 453.3 1.3 1.6e-134 449.0 0.9 2.4 1 1 0 1 1 1 1 Phosphoglucose isomerase BIR PF00653.16 KRH93698.1 - 2e-16 60.1 4.5 2.9e-11 43.6 0.3 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PepSY_TM_3 PF13706.1 KRH93699.1 - 0.036 13.4 2.4 0.06 12.7 1.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUF161 PF02588.10 KRH93699.1 - 0.081 13.2 3.7 0.11 12.8 2.5 1.2 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DUF751 PF05421.6 KRH93699.1 - 0.13 12.5 3.0 0.23 11.7 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF751) HSP90 PF00183.13 KRH93701.1 - 6.4e-09 34.7 10.6 1.6e-07 30.0 2.6 2.4 2 0 0 2 2 2 2 Hsp90 protein GDPD PF03009.12 KRH93702.1 - 1.9e-21 76.7 1.0 5.9e-21 75.1 0.7 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2763 PF10961.3 KRH93703.1 - 0.78 10.1 0.0 0.78 10.1 0.0 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF2763) RYDR_ITPR PF01365.16 KRH93705.1 - 0.11 11.7 0.3 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 RIH domain DDE_Tnp_IS1595 PF12762.2 KRH93706.1 - 8.3e-05 22.4 0.0 0.00022 21.0 0.0 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Brr6_like_C_C PF10104.4 KRH93707.1 - 1.7e-21 76.1 3.8 2.4e-21 75.6 2.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ER_lumen_recept PF00810.13 KRH93707.1 - 0.39 11.1 5.9 0.51 10.8 0.6 2.1 2 0 0 2 2 2 0 ER lumen protein retaining receptor TB2_DP1_HVA22 PF03134.14 KRH93707.1 - 8.3 6.2 7.3 1.1 9.0 0.9 2.0 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Exo_endo_phos PF03372.18 KRH93708.1 - 2.1e-12 47.5 0.2 2.8e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KRH93708.1 - 1.8e-08 33.9 0.2 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase B1 PF02246.10 KRH93709.1 - 0.12 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein L b1 domain Methuselah_N PF06652.7 KRH93710.1 - 0.027 14.0 1.0 0.03 13.8 0.7 1.1 1 0 0 1 1 1 0 Methuselah N-terminus Pneumovirus_M2 PF06436.6 KRH93710.1 - 0.085 12.0 3.2 0.1 11.8 2.2 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) DUF3338 PF11819.3 KRH93710.1 - 0.16 11.4 6.1 0.28 10.6 4.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) HALZ PF02183.13 KRH93710.1 - 0.16 11.6 6.4 0.099 12.3 2.2 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF948 PF06103.6 KRH93710.1 - 0.29 11.0 4.3 0.36 10.7 3.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 KRH93710.1 - 0.55 9.7 12.0 0.98 8.9 4.0 2.2 1 1 1 2 2 2 0 Septum formation initiator Apt1 PF10351.4 KRH93710.1 - 0.65 8.7 6.1 0.67 8.7 4.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain IATP PF04568.7 KRH93710.1 - 0.66 10.0 4.8 1.3 9.0 3.1 1.7 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ETRAMP PF09716.5 KRH93710.1 - 5.4 7.0 6.6 29 4.7 4.6 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Atg14 PF10186.4 KRH93711.1 - 0.04 12.8 5.1 0.07 12.0 3.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Imm10 PF15562.1 KRH93711.1 - 0.048 13.4 0.4 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 Immunity protein 10 Torsin PF06309.6 KRH93711.1 - 0.061 13.2 0.6 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Torsin RabGAP-TBC PF00566.13 KRH93713.1 - 2.3e-31 108.9 12.9 1.4e-28 99.8 0.8 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Pkinase PF00069.20 KRH93714.1 - 7.8e-34 116.9 4.0 7.8e-34 116.9 2.8 3.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93714.1 - 3e-16 59.2 0.5 4.1e-08 32.6 0.1 2.8 2 0 0 2 2 2 2 Protein tyrosine kinase Prok-RING_1 PF14446.1 KRH93714.1 - 7.5e-05 22.3 4.7 0.00019 21.0 3.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 KRH93714.1 - 0.0071 16.0 9.6 0.03 14.0 6.8 2.0 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KRH93714.1 - 0.14 11.5 7.3 0.46 9.8 5.0 2.0 1 1 0 1 1 1 0 PHD-finger GTP_EFTU PF00009.22 KRH93716.1 - 2.2e-39 134.8 0.1 4e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KRH93716.1 - 5.6e-25 87.2 0.2 1.2e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KRH93716.1 - 6.4e-07 29.3 0.4 1.5e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KRH93716.1 - 0.00055 19.8 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase LytTR PF04397.10 KRH93716.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.1 3 0 0 3 3 3 0 LytTr DNA-binding domain Metallophos PF00149.23 KRH93718.1 - 6e-12 45.3 0.5 6e-12 45.3 0.4 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 KRH93718.1 - 0.081 12.5 2.0 0.41 10.3 0.5 2.7 2 1 0 2 2 2 0 TPR repeat CIAPIN1 PF05093.8 KRH93719.1 - 2.3e-15 56.5 9.7 3.6e-15 55.8 6.7 1.4 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis EURL PF06937.6 KRH93719.1 - 0.096 12.0 0.6 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 EURL protein Calc_CGRP_IAPP PF00214.14 KRH93719.1 - 0.096 12.7 2.1 0.15 12.0 1.5 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF3795 PF12675.2 KRH93719.1 - 1.4 9.1 11.9 2.8 8.1 6.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) GNAT_acetyltr_2 PF13718.1 KRH93722.1 - 3.8e-36 124.2 0.0 5.8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Acetyltransf_7 PF13508.1 KRH93722.1 - 0.00012 22.2 0.1 0.00038 20.5 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA_bind_2 PF13725.1 KRH93722.1 - 0.00019 21.4 0.3 0.00067 19.7 0.1 2.0 3 0 0 3 3 3 1 Possible tRNA binding domain Acetyltransf_3 PF13302.1 KRH93722.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KRH93722.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Exo_endo_phos PF03372.18 KRH93723.1 - 7.8e-11 42.3 0.0 1.8e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.19 KRH93724.1 - 7.6e-28 97.5 0.0 2.1e-27 96.0 0.0 1.9 1 1 0 1 1 1 1 Metallopeptidase family M24 DUF4492 PF14899.1 KRH93728.1 - 5.2 6.6 9.1 11 5.5 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4492) DUF1682 PF07946.9 KRH93729.1 - 0.0035 16.2 8.3 0.0046 15.8 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SID-1_RNA_chan PF13965.1 KRH93729.1 - 0.04 12.0 1.5 0.044 11.9 1.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HSBP1 PF06825.7 KRH93729.1 - 0.078 12.5 1.6 0.42 10.2 1.1 2.0 1 1 0 1 1 1 0 Heat shock factor binding protein 1 ETRAMP PF09716.5 KRH93729.1 - 0.22 11.4 2.9 0.56 10.1 2.0 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FAM176 PF14851.1 KRH93729.1 - 0.26 10.9 3.6 0.74 9.4 2.5 1.8 1 1 0 1 1 1 0 FAM176 family Pal1 PF08316.6 KRH93729.1 - 0.28 11.6 2.3 0.37 11.2 1.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Queuosine_synth PF02547.10 KRH93729.1 - 0.6 8.7 4.3 1 8.0 3.0 1.4 1 1 0 1 1 1 0 Queuosine biosynthesis protein DUF3043 PF11241.3 KRH93729.1 - 8.6 5.9 7.3 15 5.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF3671 PF12420.3 KRH93730.1 - 2.1 8.3 9.1 3.9 7.4 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function Beta-Casp PF10996.3 KRH93732.1 - 1.5e-30 105.6 0.2 6.2e-30 103.7 0.1 2.2 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.2 KRH93732.1 - 3.8e-15 55.9 0.8 9.8e-15 54.6 0.5 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KRH93732.1 - 7.4e-12 45.3 0.8 2.9e-11 43.3 0.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KRH93732.1 - 1.9e-09 37.1 0.0 4.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase WD40 PF00400.27 KRH93733.1 - 0.00025 20.7 0.5 0.94 9.4 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TFIIE_beta PF02186.10 KRH93734.1 - 2.2e-07 30.7 0.4 2.2e-07 30.7 0.3 2.3 3 0 0 3 3 3 1 TFIIE beta subunit core domain zf-CSL PF05207.8 KRH93737.1 - 0.076 12.5 1.2 0.15 11.5 0.8 1.7 1 1 0 1 1 1 0 CSL zinc finger Trehalase_Ca-bi PF07492.6 KRH93738.1 - 1.1 8.5 3.2 5.1 6.4 0.5 2.2 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain MFS_2 PF13347.1 KRH93741.1 - 0.018 13.4 0.0 0.02 13.2 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF4083 PF13314.1 KRH93741.1 - 0.034 13.9 0.5 0.056 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) ABC2_membrane_3 PF12698.2 KRH93741.1 - 0.046 12.7 0.7 0.05 12.6 0.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein BRCT PF00533.21 KRH93742.1 - 1.8e-09 37.6 15.2 0.00016 21.7 0.1 6.1 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KRH93742.1 - 9e-05 22.2 0.1 0.0018 18.1 0.0 2.9 2 0 0 2 2 2 1 twin BRCT domain WD40 PF00400.27 KRH93743.1 - 1.4e-09 37.4 0.5 0.011 15.6 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat UspB PF10625.4 KRH93743.1 - 0.038 13.7 0.2 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Universal stress protein B (UspB) IBN_N PF03810.14 KRH93745.1 - 0.0013 18.5 0.0 0.0074 16.1 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.17 KRH93745.1 - 0.015 15.3 0.1 10 6.5 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.1 KRH93745.1 - 0.061 13.6 0.0 27 5.1 0.0 3.3 2 1 1 3 3 3 0 HEAT repeats DDE_1 PF03184.14 KRH93746.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3921 PF13060.1 KRH93749.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) DUF2956 PF11169.3 KRH93750.1 - 0.1 12.5 3.1 0.053 13.4 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) LRR_4 PF12799.2 KRH93752.1 - 6.1e-18 64.0 37.3 2.7e-05 23.6 2.3 6.8 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KRH93752.1 - 4.4e-15 55.1 30.7 5.1e-05 22.9 1.5 5.4 3 2 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 KRH93752.1 - 1.7e-09 36.3 24.5 0.99 9.6 0.2 9.2 5 2 2 7 7 7 5 Leucine Rich Repeat FNIP PF05725.7 KRH93752.1 - 4.9e-09 35.9 0.0 0.001 19.0 0.0 4.6 3 2 0 3 3 3 2 FNIP Repeat LRR_6 PF13516.1 KRH93752.1 - 4.6e-06 26.1 25.8 3.7 7.8 0.3 9.5 5 2 3 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 KRH93752.1 - 0.00031 20.4 22.6 6.3 7.4 0.1 8.6 8 1 0 8 8 8 2 Leucine rich repeat LRR_9 PF14580.1 KRH93752.1 - 0.0032 17.0 12.1 0.016 14.8 2.6 3.3 1 1 2 3 3 3 2 Leucine-rich repeat DUF648 PF04890.8 KRH93753.1 - 0.084 12.0 0.1 0.087 11.9 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF648) rve PF00665.21 KRH93757.1 - 1.5e-20 73.5 0.7 3e-18 66.0 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.22 KRH93757.1 - 1.5e-20 73.4 0.2 4.6e-20 71.9 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 KRH93757.1 - 3.9e-09 36.8 0.0 8.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH93757.1 - 1.7e-05 24.5 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH93757.1 - 2.2e-05 24.3 0.0 5.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH93757.1 - 8.2e-05 22.1 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH93757.1 - 0.00012 21.9 0.2 0.00044 20.1 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 KRH93757.1 - 0.0057 16.1 0.0 0.35 10.4 0.0 3.0 2 0 0 2 2 2 1 Integrase core domain Autoind_bind PF03472.10 KRH93758.1 - 0.31 10.3 0.1 0.6 9.3 0.1 1.4 1 0 0 1 1 1 0 Autoinducer binding domain DUF1189 PF06691.6 KRH93758.1 - 3.8 6.7 7.7 1.3 8.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Ribosomal_L30_N PF08079.7 KRH93763.1 - 0.0084 16.1 5.3 0.0084 16.1 3.6 1.5 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain DUF2407_C PF13373.1 KRH93763.1 - 0.03 14.2 0.6 0.03 14.2 0.4 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF2963 PF11178.3 KRH93763.1 - 1.5 8.3 7.7 1.2 8.6 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2963) RVT_1 PF00078.22 KRH93767.1 - 1.4e-23 83.4 0.1 3.2e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93767.1 - 5.6e-19 68.4 0.0 2.3e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF4354 PF14263.1 KRH93768.1 - 0.12 12.0 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) zf-BED PF02892.10 KRH93769.1 - 0.049 13.4 0.8 0.14 11.9 0.5 1.8 1 1 0 1 1 1 0 BED zinc finger RabGAP-TBC PF00566.13 KRH93770.1 - 3.1e-34 118.3 27.8 8.1e-34 116.9 15.5 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Gti1_Pac2 PF09729.4 KRH93770.1 - 5.1 6.9 9.6 0.73 9.6 2.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF912 PF06024.7 KRH93774.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PB1 PF00564.19 KRH93775.1 - 0.02 14.5 1.0 0.1 12.2 0.1 2.4 3 0 0 3 3 3 0 PB1 domain Bromodomain PF00439.20 KRH93778.1 - 5.4e-05 23.0 1.2 5.4e-05 23.0 0.9 2.7 3 1 0 3 3 3 1 Bromodomain Dioxygenase_N PF04444.9 KRH93778.1 - 0.14 12.1 0.3 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Catechol dioxygenase N terminus GTP_EFTU PF00009.22 KRH93779.1 - 1.4e-27 96.3 2.5 3.7e-27 94.9 0.3 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KRH93779.1 - 3.4e-13 49.4 5.2 9.4e-13 47.9 3.6 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KRH93779.1 - 3.9e-13 49.3 0.6 4.1e-07 30.0 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KRH93779.1 - 1.6e-07 30.8 1.8 2.7e-07 30.1 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KRH93779.1 - 1.5e-05 24.8 0.1 1.5e-05 24.8 0.0 3.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase Ras PF00071.17 KRH93779.1 - 0.0069 15.7 0.0 0.031 13.6 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.1 KRH93779.1 - 0.0078 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KRH93779.1 - 0.0088 16.5 0.9 0.047 14.1 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein IF-2B PF01008.12 KRH93780.1 - 0.038 12.9 1.9 0.07 12.1 1.3 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family Bacillus_HBL PF05791.6 KRH93782.1 - 0.0007 19.0 1.1 0.87 8.9 0.0 2.4 2 0 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) ICAP-1_inte_bdg PF10480.4 KRH93782.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Beta-1 integrin binding protein Peptidase_M16_C PF05193.16 KRH93782.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16 inactive domain HEPN PF05168.9 KRH93782.1 - 0.17 11.7 1.2 11 5.9 0.1 2.4 2 0 0 2 2 2 0 HEPN domain DASH_Duo1 PF08651.5 KRH93782.1 - 0.46 10.1 3.5 1.9 8.1 1.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 S-AdoMet_synt_C PF02773.11 KRH93783.1 - 8e-56 187.5 0.2 1.4e-55 186.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KRH93783.1 - 6.4e-28 97.1 0.0 3.3e-27 94.8 0.0 2.1 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KRH93783.1 - 2.5e-23 82.2 0.1 6.7e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Peptidase_M57 PF12388.3 KRH93784.1 - 0.023 14.0 0.0 0.067 12.5 0.0 1.7 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Copine PF07002.11 KRH93784.1 - 0.089 12.5 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Copine Ribosomal_L37ae PF01780.14 KRH93785.1 - 5.8e-30 103.0 6.7 6.5e-30 102.8 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KRH93785.1 - 0.0016 18.1 5.5 0.0023 17.7 3.8 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 KRH93785.1 - 0.014 14.9 0.4 0.014 14.9 0.3 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 KRH93785.1 - 0.029 14.6 7.5 0.16 12.3 2.8 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 KRH93785.1 - 0.033 13.3 1.9 0.55 9.5 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KRH93785.1 - 0.042 13.7 1.2 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KRH93785.1 - 0.062 12.9 2.5 0.087 12.4 1.7 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 KRH93785.1 - 0.08 13.2 2.0 0.21 11.9 1.4 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-BED PF02892.10 KRH93785.1 - 0.081 12.6 6.2 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 KRH93785.1 - 0.35 11.3 1.5 8.4 6.9 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.1 KRH93785.1 - 0.36 10.3 3.8 0.99 8.9 0.8 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 KRH93785.1 - 0.79 9.5 4.3 2.1 8.1 1.1 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Mcm10 PF09332.6 KRH93785.1 - 1 8.6 4.6 1.2 8.3 3.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor zf-MIZ PF02891.15 KRH93785.1 - 1.6 8.3 6.1 2.6 7.6 0.2 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prim_Zn_Ribbon PF08273.7 KRH93785.1 - 1.7 8.7 5.3 16 5.6 3.7 2.1 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-C2HC5 PF06221.8 KRH93785.1 - 3 7.6 5.7 2.1 8.1 0.6 2.1 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2 PF00096.21 KRH93785.1 - 4.2 7.9 5.4 12 6.4 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DDE_Tnp_IS1595 PF12762.2 KRH93787.1 - 2.4e-10 40.4 0.0 3.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 KRH93787.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Transposase IS66 family rve PF00665.21 KRH93787.1 - 0.037 14.1 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FliG_C PF01706.11 KRH93787.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 FliG C-terminal domain DUF4369 PF14289.1 KRH93790.1 - 0.13 12.2 0.7 1.1 9.2 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4369) SAC3_GANP PF03399.11 KRH93791.1 - 3.2e-07 30.1 10.6 5.5e-06 26.0 7.3 2.6 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ORC6 PF05460.8 KRH93791.1 - 0.032 13.3 4.2 0.058 12.4 2.9 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Homeobox PF00046.24 KRH93793.1 - 3.4e-21 74.6 1.7 3.9e-21 74.4 0.4 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 KRH93793.1 - 0.024 14.3 0.0 0.024 14.3 0.0 2.5 4 0 0 4 4 4 0 Homeobox KN domain SNF2_N PF00176.18 KRH93794.1 - 3.2e-59 200.1 0.0 7.4e-59 198.9 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KRH93794.1 - 5e-15 55.1 0.0 1.5e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KRH93794.1 - 1e-07 31.8 5.3 1e-07 31.8 3.7 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KRH93794.1 - 2.6e-06 27.1 3.6 2.6e-06 27.1 2.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KRH93794.1 - 4e-06 26.4 3.3 4e-06 26.4 2.3 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH93794.1 - 0.0011 18.6 6.0 0.0011 18.6 4.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KRH93794.1 - 0.009 15.7 1.5 0.032 13.9 1.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger PWWP PF00855.12 KRH93795.1 - 4.5e-08 33.1 0.1 4.5e-08 33.1 0.1 3.9 3 2 0 3 3 3 1 PWWP domain UQ_con PF00179.21 KRH93796.1 - 1.7e-44 150.6 0.2 1.9e-44 150.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KRH93796.1 - 1.9e-07 30.9 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KRH93796.1 - 9.1e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KRH93796.1 - 0.018 14.7 0.2 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain PGA2 PF07543.7 KRH93796.1 - 0.075 12.8 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 RNB PF00773.14 KRH93797.1 - 1.8e-76 257.5 8.0 1.8e-76 257.5 5.6 1.8 2 0 0 2 2 2 1 RNB domain rve PF00665.21 KRH93800.1 - 6.2e-20 71.5 0.0 1.5e-19 70.3 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH93800.1 - 0.011 15.2 0.1 0.032 13.7 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain Ricin_B_lectin PF00652.17 KRH93802.1 - 7.3e-05 22.7 0.1 0.00016 21.6 0.0 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 KRH93802.1 - 0.0085 15.4 1.3 0.015 14.7 0.3 1.9 1 1 1 2 2 2 1 Cytolethal distending toxin A/C family DED PF01335.16 KRH93802.1 - 0.042 13.9 1.4 0.087 12.9 1.0 1.5 1 1 0 1 1 1 0 Death effector domain Pentapeptide_4 PF13599.1 KRH93803.1 - 4.6e-06 26.3 2.9 5.6e-06 26.0 2.0 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 KRH93803.1 - 0.0019 17.4 1.5 0.0022 17.1 0.4 1.7 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 KRH93803.1 - 0.008 16.0 4.0 0.02 14.8 2.7 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Kelch_4 PF13418.1 KRH93803.1 - 7.5 6.4 9.0 27 4.6 0.2 3.3 2 2 0 2 2 2 0 Galactose oxidase, central domain DENN PF02141.16 KRH93805.1 - 5.5e-10 39.2 0.7 2.6e-09 37.0 0.1 2.3 2 0 0 2 2 2 1 DENN (AEX-3) domain Chordopox_RPO7 PF05864.7 KRH93805.1 - 0.0069 16.4 1.0 0.022 14.8 0.2 2.3 2 0 0 2 2 2 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF2346 PF09803.4 KRH93806.1 - 0.11 12.3 2.6 0.13 12.0 1.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) HMG_box_5 PF14887.1 KRH93806.1 - 0.12 12.2 4.3 0.14 11.9 3.0 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box 5 zf-PHD-like PF15446.1 KRH93806.1 - 0.15 11.3 1.2 0.16 11.2 0.8 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF2724 PF10893.3 KRH93806.1 - 0.53 10.1 3.4 0.65 9.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) DUF3513 PF12026.3 KRH93806.1 - 2.3 7.7 5.8 2.4 7.6 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Mt_ATP-synt_D PF05873.7 KRH93807.1 - 0.087 12.4 0.1 0.087 12.4 0.1 1.0 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Spc97_Spc98 PF04130.8 KRH93808.1 - 2e-13 49.5 22.6 2e-13 49.5 15.7 1.9 1 1 1 2 2 2 2 Spc97 / Spc98 family XPG_I PF00867.13 KRH93809.1 - 1.1e-26 92.6 0.1 4.2e-26 90.8 0.1 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KRH93809.1 - 1.1e-21 76.9 0.1 2.5e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF2458 PF10454.4 KRH93809.1 - 0.0012 18.6 0.9 0.0012 18.6 0.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2458) 5_3_exonuc PF01367.15 KRH93809.1 - 0.0014 18.8 0.1 0.0051 17.0 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold RecX PF02631.11 KRH93809.1 - 0.015 15.4 0.2 0.015 15.4 0.1 2.1 2 0 0 2 2 2 0 RecX family DUF106 PF01956.11 KRH93809.1 - 0.18 11.3 2.2 0.42 10.1 1.5 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3340 PF11818.3 KRH93809.1 - 4 7.4 7.7 4.6 7.1 0.6 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Sugar_tr PF00083.19 KRH93810.1 - 1.1e-16 60.4 5.7 5.1e-15 54.9 3.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter YIF1 PF03878.10 KRH93810.1 - 0.11 11.6 2.9 0.32 10.0 2.0 1.7 1 1 0 1 1 1 0 YIF1 DUF3526 PF12040.3 KRH93810.1 - 0.13 12.3 0.1 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Disaggr_assoc PF08480.5 KRH93811.1 - 0.01 15.2 1.1 0.02 14.3 0.7 1.6 1 1 0 1 1 1 0 Disaggregatase related RelB PF04221.7 KRH93812.1 - 0.089 12.5 2.7 0.93 9.2 0.0 3.3 3 0 0 3 3 3 0 RelB antitoxin Noggin PF05806.7 KRH93812.1 - 0.12 11.6 0.6 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Noggin EamA PF00892.15 KRH93813.1 - 1.7e-07 31.3 2.5 2.4e-07 30.8 1.7 1.3 1 0 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 KRH93813.1 - 0.00017 21.7 0.2 0.00026 21.1 0.2 1.2 1 0 0 1 1 1 1 Multidrug resistance efflux transporter DUF1700 PF08006.6 KRH93813.1 - 0.0045 16.3 4.1 0.0053 16.0 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) TPT PF03151.11 KRH93813.1 - 0.0048 16.5 3.0 0.019 14.5 0.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KRH93813.1 - 0.0078 15.1 5.0 0.0086 15.0 3.4 1.1 1 0 0 1 1 1 1 UAA transporter family Sarcoglycan_2 PF05510.8 KRH93814.1 - 0.021 13.1 0.4 0.023 12.9 0.3 1.0 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Pho88 PF10032.4 KRH93814.1 - 0.061 12.5 0.2 0.09 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) Pex24p PF06398.6 KRH93814.1 - 0.094 11.4 1.2 0.1 11.3 0.8 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Myf5 PF12232.3 KRH93814.1 - 0.23 12.1 2.6 0.31 11.6 1.6 1.4 1 1 0 1 1 1 0 Myogenic determination factor 5 DUF606 PF04657.8 KRH93815.1 - 0.19 11.8 0.2 0.19 11.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function, DUF606 GRASP55_65 PF04495.9 KRH93816.1 - 4.1e-20 72.1 0.0 9.5e-15 54.8 0.0 2.4 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KRH93816.1 - 8.6e-07 28.7 0.1 0.0042 16.9 0.0 3.0 3 0 0 3 3 3 2 PDZ domain NAD_Gly3P_dh_C PF07479.9 KRH93817.1 - 7.2e-36 123.1 0.4 2e-35 121.6 0.3 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KRH93817.1 - 1.3e-28 99.6 0.0 2.1e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IF2_N PF04760.10 KRH93817.1 - 0.011 15.3 0.4 0.75 9.4 0.0 3.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region F420_oxidored PF03807.12 KRH93817.1 - 0.013 15.9 0.2 6.1 7.3 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2207 PF09972.4 KRH93818.1 - 0.15 10.5 0.6 0.16 10.5 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_3 PF13358.1 KRH93819.1 - 1.7e-25 89.4 0.1 3.5e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 KRH93819.1 - 0.005 16.9 0.1 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 KRH93819.1 - 0.02 14.0 2.0 0.031 13.4 0.0 2.1 2 1 1 3 3 3 0 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 KRH93819.1 - 0.025 13.3 2.8 0.14 10.8 0.1 2.4 2 1 0 2 2 2 0 Rhodopirellula transposase DDE domain Arg_repressor PF01316.16 KRH93819.1 - 0.027 14.0 1.3 0.055 13.0 0.9 1.5 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain ABC_tran PF00005.22 KRH93820.1 - 7.1e-25 87.9 0.0 1.8e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ATP-synt_ab PF00006.20 KRH93820.1 - 0.0011 18.4 0.1 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 KRH93820.1 - 0.078 12.2 5.9 3.2 6.9 0.0 2.9 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KRH93820.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KRH93820.1 - 0.34 10.5 5.3 0.48 10.0 0.1 3.2 4 1 0 4 4 4 0 NACHT domain MS_channel PF00924.13 KRH93821.1 - 3.7e-19 68.8 0.5 6.9e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel Sec62 PF03839.11 KRH93821.1 - 0.59 9.5 9.9 3.4 7.0 6.8 2.3 1 1 0 1 1 1 0 Translocation protein Sec62 Spore_coat_CotO PF14153.1 KRH93821.1 - 2.4 7.5 23.6 1.6 8.1 12.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF1242 PF06842.7 KRH93822.1 - 3.4e-09 36.0 0.6 6.7e-09 35.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) DUF167 PF02594.11 KRH93823.1 - 2.8e-22 78.4 3.5 3.8e-22 77.9 2.4 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Peptidase_C48 PF02902.14 KRH93825.1 - 2e-07 30.8 0.1 7e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KRH93825.1 - 0.00017 20.2 1.5 0.023 13.2 0.0 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase Myb_DNA-bind_4 PF13837.1 KRH93826.1 - 0.29 11.2 3.0 2.3 8.4 2.5 1.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Topoisom_I_N PF02919.10 KRH93826.1 - 0.36 10.0 3.0 0.47 9.7 2.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment AAA_23 PF13476.1 KRH93826.1 - 0.6 10.4 6.0 0.7 10.1 4.2 1.1 1 0 0 1 1 1 0 AAA domain DUF4482 PF14818.1 KRH93826.1 - 0.91 10.1 7.3 0.32 11.6 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Vma12 PF11712.3 KRH93826.1 - 1.3 8.7 3.9 2.2 7.9 2.7 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase IncA PF04156.9 KRH93826.1 - 2 7.9 6.7 4.2 6.9 4.6 1.6 1 1 0 1 1 1 0 IncA protein RVT_1 PF00078.22 KRH93827.1 - 0.00059 19.2 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KRH93828.1 - 3.7e-14 52.5 0.1 5.5e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH93830.1 - 8.7e-21 74.2 0.0 1.9e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93830.1 - 0.00013 21.3 0.1 0.0044 16.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 KRH93830.1 - 0.039 13.3 0.3 0.039 13.3 0.2 2.5 3 0 0 3 3 3 0 His(2)-Cys(2) zinc finger DUF1256 PF06866.6 KRH93830.1 - 0.052 12.7 0.6 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) ArsA_ATPase PF02374.10 KRH93831.1 - 6e-23 81.3 3.9 2.2e-22 79.5 2.7 1.7 1 1 0 1 1 1 1 Anion-transporting ATPase Transposase_28 PF04195.7 KRH93831.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative gypsy type transposon LRR_4 PF12799.2 KRH93831.1 - 0.099 12.2 0.1 0.099 12.2 0.1 2.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) rve PF00665.21 KRH93832.1 - 1.8e-23 82.9 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93832.1 - 0.012 15.1 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain DUF1758 PF05585.7 KRH93832.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H2C2 PF09337.5 KRH93832.1 - 0.41 10.1 11.3 0.17 11.2 2.5 3.0 3 0 0 3 3 3 0 His(2)-Cys(2) zinc finger Flavi_glycop_C PF02832.11 KRH93833.1 - 0.099 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain RVT_1 PF00078.22 KRH93834.1 - 3.1e-10 39.7 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH93834.1 - 5e-06 26.1 1.1 1.2e-05 24.9 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Striatin PF08232.7 KRH93834.1 - 0.0082 16.4 2.3 0.02 15.2 1.6 1.6 1 0 0 1 1 1 1 Striatin family zf-CCHC_4 PF14392.1 KRH93834.1 - 0.23 11.1 4.4 0.46 10.2 0.8 2.6 2 0 0 2 2 2 0 Zinc knuckle M PF02370.11 KRH93834.1 - 0.36 11.3 3.3 1.5 9.4 2.3 2.1 1 0 0 1 1 1 0 M protein repeat IncA PF04156.9 KRH93834.1 - 1.3 8.6 3.5 1.9 8.0 2.0 1.4 1 1 0 1 1 1 0 IncA protein IFT20 PF14931.1 KRH93837.1 - 0.068 13.0 0.5 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF4537 PF15057.1 KRH93839.1 - 0.023 14.4 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF3201 PF11447.3 KRH93839.1 - 0.049 13.0 0.1 0.064 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) SH3_2 PF07653.12 KRH93839.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain PMM PF03332.8 KRH93842.1 - 0.1 12.1 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Peptidase_S64 PF08192.6 KRH93844.1 - 2 6.6 40.0 0.059 11.6 23.3 1.5 2 0 0 2 2 2 0 Peptidase family S64 DnaJ PF00226.26 KRH93845.1 - 5.4e-05 22.8 3.0 0.00037 20.1 0.5 2.7 2 1 0 2 2 2 1 DnaJ domain SAM_decarbox PF01536.11 KRH93845.1 - 0.096 11.3 0.9 0.12 10.9 0.6 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Syntaxin_2 PF14523.1 KRH93845.1 - 0.15 12.1 5.4 0.21 11.6 3.6 1.4 1 1 0 1 1 1 0 Syntaxin-like protein PP1_inhibitor PF05361.7 KRH93845.1 - 0.79 9.4 5.3 0.62 9.7 2.2 1.6 1 1 1 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor Chorein_N PF12624.2 KRH93848.1 - 4.2e-13 48.8 2.3 2.9e-12 46.1 1.6 2.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PI3_PI4_kinase PF00454.22 KRH93850.1 - 2.7e-24 85.9 2.2 4.5e-23 81.9 0.1 3.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Ada3 PF10198.4 KRH93852.1 - 3.1e-05 23.7 7.6 3.1e-05 23.7 5.3 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Rep_fac_C PF08542.6 KRH93853.1 - 7.5e-17 61.0 0.2 2.6e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KRH93853.1 - 6.6e-12 45.3 0.9 6.6e-12 45.3 0.6 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Arch_ATPase PF01637.13 KRH93853.1 - 9.8e-06 25.4 2.9 9.8e-06 25.4 2.0 2.1 1 1 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 KRH93853.1 - 0.00042 20.3 0.1 0.013 15.5 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KRH93853.1 - 0.00046 20.1 3.3 0.0024 17.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KRH93853.1 - 0.00065 19.8 5.4 0.0054 16.8 0.6 2.6 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 KRH93853.1 - 0.0011 19.3 16.7 0.0041 17.4 11.6 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KRH93853.1 - 0.0018 17.2 0.0 0.0044 15.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KRH93853.1 - 0.0019 18.3 0.4 0.011 15.9 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KRH93853.1 - 0.0057 16.8 0.3 0.024 14.8 0.1 2.1 1 1 1 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 KRH93853.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KRH93853.1 - 0.076 13.8 0.6 0.55 11.0 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KRH93853.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KRH93853.1 - 0.16 12.2 2.7 1.2 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KRH93853.1 - 0.19 12.0 2.1 0.62 10.3 1.4 2.0 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.8 KRH93853.1 - 0.2 10.5 4.7 2.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_21 PF13304.1 KRH93853.1 - 0.91 9.4 7.3 17 5.2 5.1 2.2 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KRH93853.1 - 2.4 7.9 10.2 90 2.7 7.1 2.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 Ribosomal_60s PF00428.14 KRH93854.1 - 1.2e-08 35.1 5.1 1.5e-08 34.9 3.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DNA_pol3_delta PF06144.8 KRH93854.1 - 0.068 12.6 0.1 0.096 12.1 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF2999 PF11212.3 KRH93854.1 - 0.077 13.0 0.1 2.2 8.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2999) IFT57 PF10498.4 KRH93854.1 - 0.1 11.3 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CLASP_N PF12348.3 KRH93855.1 - 1.3 8.3 6.9 0.21 10.8 0.4 2.9 4 0 0 4 4 4 0 CLASP N terminal DUF572 PF04502.8 KRH93856.1 - 1.1e-13 51.1 9.8 1.2e-13 50.9 6.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 KRH93856.1 - 0.0067 15.9 3.0 0.0067 15.9 2.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) ETRAMP PF09716.5 KRH93856.1 - 0.013 15.4 0.8 0.026 14.4 0.5 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-3CxxC PF13695.1 KRH93856.1 - 0.73 10.1 5.4 0.85 9.8 3.2 1.6 1 1 0 1 1 1 0 Zinc-binding domain Evr1_Alr PF04777.8 KRH93856.1 - 0.93 9.4 7.7 1 9.2 0.7 2.5 1 1 1 3 3 3 0 Erv1 / Alr family DUF2072 PF09845.4 KRH93856.1 - 1 9.2 6.0 0.58 10.0 2.1 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) RPAP2_Rtr1 PF04181.8 KRH93856.1 - 2.8 8.0 7.4 0.79 9.8 0.2 2.4 1 1 1 2 2 2 0 Rtr1/RPAP2 family Zn_ribbon_recom PF13408.1 KRH93856.1 - 3.2 8.0 5.7 0.51 10.6 0.2 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Proteasome PF00227.21 KRH93857.1 - 4.3e-42 143.5 0.5 5e-42 143.3 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit RVT_1 PF00078.22 KRH93858.1 - 2e-38 131.8 0.0 3.5e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_UBOX PF13445.1 KRH93859.1 - 3.2e-09 36.3 1.3 1.8e-08 33.9 0.9 2.5 1 0 0 1 1 1 1 RING-type zinc-finger Folliculin PF11704.3 KRH93859.1 - 1.1 8.8 13.1 0.041 13.4 0.4 2.9 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport S1FA PF04689.8 KRH93860.1 - 0.86 9.5 4.7 0.46 10.4 1.0 2.1 2 1 0 2 2 2 0 DNA binding protein S1FA Rad33 PF08730.5 KRH93861.1 - 0.71 9.3 6.9 0.1 12.0 1.6 1.9 2 1 0 2 2 2 0 Rad33 DUF3677 PF12432.3 KRH93861.1 - 1.4 9.4 4.2 3.7 8.0 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3677) HAD_2 PF13419.1 KRH93862.1 - 4.3e-15 56.3 0.0 5.7e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase IL15 PF02372.10 KRH93862.1 - 0.00025 20.8 0.2 0.00057 19.6 0.1 1.6 1 0 0 1 1 1 1 Interleukin 15 Prenyltransf PF01255.14 KRH93864.1 - 0.063 12.4 0.1 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RVT_1 PF00078.22 KRH93865.1 - 4.9e-19 68.5 0.7 1.5e-18 66.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cutinase PF01083.17 KRH93865.1 - 0.057 13.1 0.3 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Cutinase Bac_DnaA PF00308.13 KRH93865.1 - 0.067 12.8 0.1 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein AAA PF00004.24 KRH93870.1 - 1.8e-48 164.0 0.0 6.5e-46 155.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KRH93870.1 - 3.6e-10 39.8 1.4 1.5e-06 28.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain RuvB_N PF05496.7 KRH93870.1 - 5.6e-08 32.1 0.0 3.4e-07 29.5 0.0 2.2 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KRH93870.1 - 5.7e-08 32.9 0.2 5e-05 23.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KRH93870.1 - 2.8e-07 31.3 0.4 0.00015 22.6 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KRH93870.1 - 7.3e-07 29.2 0.0 2e-06 27.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KRH93870.1 - 1.4e-06 28.6 0.9 0.00022 21.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KRH93870.1 - 3.8e-06 26.6 0.1 2.4e-05 24.0 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KRH93870.1 - 8.3e-06 25.5 0.2 0.027 14.1 0.0 3.7 2 1 1 3 3 3 1 NACHT domain AAA_23 PF13476.1 KRH93870.1 - 3.3e-05 24.2 3.4 0.0019 18.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KRH93870.1 - 5.9e-05 23.1 0.1 0.014 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KRH93870.1 - 6.8e-05 22.6 2.9 0.0028 17.4 0.0 3.6 2 2 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 KRH93870.1 - 0.00013 22.0 0.0 0.00058 20.0 0.0 2.1 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.16 KRH93870.1 - 0.00014 21.1 0.0 0.00043 19.5 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KRH93870.1 - 0.00031 19.9 0.0 0.00083 18.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 KRH93870.1 - 0.00034 19.6 0.0 0.0048 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KRH93870.1 - 0.0012 17.6 0.0 0.0022 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KRH93870.1 - 0.0015 18.0 0.0 0.0039 16.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KRH93870.1 - 0.0031 16.9 0.0 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KRH93870.1 - 0.0043 16.9 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KRH93870.1 - 0.0088 16.3 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SKI PF01202.17 KRH93870.1 - 0.01 15.7 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase AAA_19 PF13245.1 KRH93870.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KRH93870.1 - 0.012 15.1 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KRH93870.1 - 0.013 14.3 0.1 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KRH93870.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KRH93870.1 - 0.014 15.0 0.0 0.085 12.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KRH93870.1 - 0.017 14.5 0.1 0.62 9.5 0.0 3.1 2 2 1 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 KRH93870.1 - 0.018 14.1 0.2 0.11 11.6 0.0 2.3 2 1 0 2 2 2 0 KaiC T2SE PF00437.15 KRH93870.1 - 0.031 13.1 0.0 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 KRH93870.1 - 0.038 13.5 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 KRH93870.1 - 0.054 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KRH93870.1 - 0.055 13.0 0.0 0.75 9.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 KRH93870.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KRH93870.1 - 0.091 12.1 0.3 0.76 9.1 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_3 PF07726.6 KRH93870.1 - 0.098 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KRH93870.1 - 0.15 11.6 0.0 0.49 9.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 KRH93870.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ham1p_like PF01725.11 KRH93871.1 - 1e-28 100.0 0.1 1.2e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.11 KRH93872.1 - 1.4e-06 27.8 0.2 2.3e-06 27.1 0.1 1.3 1 1 0 1 1 1 1 Ham1 family NEMO PF11577.3 KRH93872.1 - 0.00076 19.1 2.4 0.013 15.2 0.1 2.4 2 0 0 2 2 2 1 NF-kappa-B essential modulator NEMO DUF2959 PF11172.3 KRH93872.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF1160 PF06648.6 KRH93872.1 - 0.067 12.9 0.3 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) End3 PF12761.2 KRH93872.1 - 0.11 12.1 3.1 0.18 11.4 2.2 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 PspB PF06667.7 KRH93872.1 - 0.21 11.5 5.7 0.056 13.3 1.5 1.8 2 0 0 2 2 2 0 Phage shock protein B RhoGAP PF00620.22 KRH93873.1 - 1.2e-07 31.5 5.2 8.6e-06 25.4 3.6 2.9 1 1 0 1 1 1 1 RhoGAP domain Retrotrans_gag PF03732.12 KRH93874.1 - 0.0014 18.6 1.6 0.0044 17.0 0.1 2.4 1 1 1 2 2 2 1 Retrotransposon gag protein DUF445 PF04286.7 KRH93874.1 - 0.019 14.5 4.3 0.037 13.5 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Herpes_BLRF2 PF05812.7 KRH93874.1 - 0.27 11.0 4.4 0.2 11.4 1.6 1.9 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein CHDNT PF08073.7 KRH93876.1 - 0.0018 17.9 1.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 CHDNT (NUC034) domain DUF2206 PF09971.4 KRH93876.1 - 0.078 11.7 6.0 0.06 12.1 2.7 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2206) HTH_23 PF13384.1 KRH93878.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 KRH93878.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_IS1595 PF12762.2 KRH93879.1 - 1.7e-13 50.6 1.1 2.1e-13 50.3 0.4 1.5 1 1 1 2 2 2 1 ISXO2-like transposase domain rve PF00665.21 KRH93880.1 - 7.9e-10 38.8 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93880.1 - 0.11 12.0 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain RNA_pol_Rpb1_5 PF04998.12 KRH93881.1 - 1.5e-70 237.6 0.2 5.4e-70 235.7 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KRH93881.1 - 1.7e-56 190.7 0.2 3.8e-56 189.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KRH93881.1 - 9.8e-45 153.2 7.5 9.8e-45 153.2 5.2 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KRH93881.1 - 3.9e-20 71.5 1.9 8.3e-20 70.5 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 KRH93881.1 - 4.7e-09 36.1 0.6 8.5e-07 28.8 0.0 3.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 3 DUF1413 PF07205.6 KRH93881.1 - 0.0041 16.6 0.1 0.016 14.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1413) DUF4571 PF15137.1 KRH93881.1 - 0.026 13.9 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4571) DUF367 PF04034.8 KRH93882.1 - 2.6e-45 153.1 0.1 3.1e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KRH93882.1 - 0.00036 20.0 0.4 0.00036 20.0 0.3 1.9 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI LEDGF PF11467.3 KRH93886.1 - 0.093 12.4 0.3 0.12 12.1 0.2 1.3 1 1 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Herpes_IE2_3 PF03361.9 KRH93886.1 - 0.1 11.8 0.2 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Lactamase_B_4 PF13691.1 KRH93887.1 - 8.2e-07 28.4 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Trypan_glycop_C PF10659.4 KRH93888.1 - 0.063 13.5 8.7 1.1 9.5 1.0 2.3 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain Peptidase_M16 PF00675.15 KRH93888.1 - 0.15 11.8 1.6 3.4 7.4 0.1 2.0 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) Herpes_UL33 PF03581.8 KRH93888.1 - 0.16 11.8 1.5 4.1 7.3 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL33-like protein DUF3617 PF12276.3 KRH93888.1 - 0.23 10.8 3.4 0.23 10.8 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) DnaJ PF00226.26 KRH93890.1 - 0.0015 18.2 0.0 0.004 16.8 0.0 1.8 1 1 1 2 2 2 1 DnaJ domain Pam16 PF03656.8 KRH93890.1 - 0.054 13.2 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Pam16 Pkinase PF00069.20 KRH93891.1 - 3.1e-45 154.3 2.4 2.3e-38 131.8 0.0 3.0 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93891.1 - 2.9e-23 82.2 0.3 1.7e-22 79.7 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH93891.1 - 3e-05 23.1 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KRH93891.1 - 0.0036 16.1 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Slp PF03843.8 KRH93891.1 - 0.055 12.4 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Kdo PF06293.9 KRH93891.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIS PF01380.17 KRH93892.1 - 4.6e-48 162.1 0.1 3.3e-29 101.1 0.1 2.7 3 0 0 3 3 3 2 SIS domain GATase_2 PF00310.16 KRH93892.1 - 4.2e-20 71.7 1.8 3.7e-13 48.9 0.2 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KRH93892.1 - 3.1e-15 56.2 0.0 1.1e-14 54.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KRH93892.1 - 1.8e-11 43.8 0.0 6.3e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KRH93892.1 - 2.1e-08 33.1 0.1 3.8e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KRH93892.1 - 7.1e-05 22.5 0.0 0.00022 20.9 0.0 1.9 2 0 0 2 2 2 1 SIS domain DUF3375 PF11855.3 KRH93892.1 - 0.29 9.8 2.7 4.4 5.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Phage_connector PF05352.7 KRH93894.1 - 0.069 12.3 0.0 0.09 11.9 0.0 1.3 1 1 0 1 1 1 0 Phage Connector (GP10) UPF1_Zn_bind PF09416.5 KRH93896.1 - 4.1e-13 49.1 10.4 1.7e-12 47.1 7.2 2.1 1 1 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Rpr2 PF04032.11 KRH93896.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-B_box PF00643.19 KRH93896.1 - 4.3 7.3 18.9 0.13 12.1 4.4 2.9 3 0 0 3 3 3 0 B-box zinc finger PRK PF00485.13 KRH93899.1 - 2.6e-13 49.9 0.0 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KRH93899.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH93899.1 - 8.1e-06 26.6 0.0 1.3e-05 25.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KRH93899.1 - 0.00034 20.3 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KRH93899.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KRH93899.1 - 0.028 14.1 0.1 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KRH93899.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 KRH93899.1 - 0.032 14.1 0.1 0.094 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KRH93899.1 - 0.052 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KRH93899.1 - 0.076 12.5 0.6 0.2 11.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.17 KRH93899.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase Pput2613-deam PF14427.1 KRH93900.1 - 0.031 13.9 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 Pput_2613-like deaminase IL8 PF00048.15 KRH93900.1 - 0.68 9.9 2.9 1.1 9.2 2.0 1.4 1 1 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like p12I PF12233.3 KRH93902.1 - 0.0078 16.4 1.3 0.0078 16.4 0.9 2.7 2 1 1 3 3 3 1 Human adult T cell leukemia/lymphoma virus protein MCM PF00493.18 KRH93903.1 - 6.1e-124 413.1 2.2 4e-122 407.1 1.5 2.1 1 1 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KRH93903.1 - 2.6e-07 30.0 0.0 7.9e-05 21.9 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KRH93903.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KRH93903.1 - 0.0046 16.5 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.1 KRH93903.1 - 0.005 17.3 2.8 0.05 14.0 0.1 3.2 2 1 1 3 3 3 1 MCM N-terminal domain Sigma54_activat PF00158.21 KRH93903.1 - 0.042 13.3 0.1 0.44 10.0 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain tRNA_U5-meth_tr PF05958.6 KRH93904.1 - 1.4e-11 43.6 0.3 3.6e-11 42.3 0.2 1.7 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KRH93904.1 - 5.7e-05 22.7 0.3 5.7e-05 22.7 0.2 3.6 3 2 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.1 KRH93904.1 - 0.02 14.5 0.7 0.068 12.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 KRH93904.1 - 0.023 15.2 0.0 0.069 13.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KRH93904.1 - 0.031 13.8 2.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Met-10+ like-protein TcdA_TcdB_pore PF12920.2 KRH93905.1 - 0.027 12.4 5.9 0.62 7.9 1.9 2.0 1 1 1 2 2 2 0 TcdA/TcdB pore forming domain Atrophin-1 PF03154.10 KRH93905.1 - 0.63 8.1 2.6 0.73 7.9 1.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family CAP_GLY PF01302.20 KRH93907.1 - 2.6e-13 49.4 0.2 5.5e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LSM PF01423.17 KRH93908.1 - 2e-07 30.4 0.0 2.5e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain RIO1 PF01163.17 KRH93909.1 - 2.3e-44 151.0 10.1 2.6e-23 82.3 2.8 3.1 2 1 1 3 3 3 2 RIO1 family APH PF01636.18 KRH93909.1 - 0.0092 15.7 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DnaA_N PF11638.3 KRH93911.1 - 0.044 13.3 0.1 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain RVT_1 PF00078.22 KRH93912.1 - 3.3e-21 75.6 0.1 5.2e-21 74.9 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH93913.1 - 0.0028 17.4 3.6 0.0075 16.1 2.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KRH93913.1 - 0.017 14.8 0.9 0.038 13.7 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Fer4_18 PF13746.1 KRH93913.1 - 0.06 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain DDE_Tnp_IS1595 PF12762.2 KRH93914.1 - 3.1e-20 72.5 0.3 4.1e-20 72.1 0.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain UPF0270 PF06794.7 KRH93914.1 - 0.066 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) MFS_2 PF13347.1 KRH93915.1 - 0.12 10.8 8.3 0.14 10.5 5.8 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein FA_hydroxylase PF04116.8 KRH93915.1 - 0.13 12.6 2.9 0.17 12.3 2.0 1.2 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily Bestrophin PF01062.16 KRH93915.1 - 0.79 8.6 6.1 0.42 9.5 3.0 1.4 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel SDH_sah PF01972.11 KRH93916.1 - 0.018 13.8 0.6 0.033 12.9 0.4 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Aminotran_1_2 PF00155.16 KRH93917.1 - 5.9e-52 176.8 0.0 6.9e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KRH93917.1 - 2.5e-05 23.5 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase eRF1_1 PF03463.10 KRH93918.1 - 1.7e-12 47.0 0.9 3.3e-12 46.1 0.6 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KRH93918.1 - 1.6e-07 31.5 1.8 2e-07 31.2 0.1 2.1 3 0 0 3 3 3 1 eRF1 domain 3 Thymidylat_synt PF00303.14 KRH93919.1 - 1e-107 359.1 0.0 1.1e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase UPF0016 PF01169.14 KRH93920.1 - 0.063 13.4 0.3 0.073 13.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 Nha1_C PF08619.5 KRH93921.1 - 0.14 11.3 7.9 0.91 8.7 1.8 2.0 1 1 1 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF1837 PF08878.6 KRH93922.1 - 0.61 9.6 10.2 0.031 13.8 1.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1837) Pkinase PF00069.20 KRH93923.1 - 2e-44 151.7 0.0 4.6e-44 150.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93923.1 - 3e-21 75.6 0.0 4.8e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH93923.1 - 6.7e-05 21.9 0.0 0.00024 20.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KRH93923.1 - 0.0045 16.3 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Adipokin_hormo PF06377.6 KRH93924.1 - 1.1e-06 28.6 9.2 1.4 9.1 0.0 6.9 1 1 7 10 10 10 3 Adipokinetic hormone Complex1_30kDa PF00329.14 KRH93924.1 - 2.7 8.2 8.4 38 4.5 0.1 3.6 1 1 3 4 4 4 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zinc_ribbon_5 PF13719.1 KRH93928.1 - 0.0019 17.7 3.4 0.0029 17.1 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KRH93928.1 - 0.0054 16.3 3.7 0.0066 16.1 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.4 KRH93928.1 - 0.0069 16.0 4.7 0.03 14.0 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 DUF35_N PF12172.3 KRH93928.1 - 0.017 15.0 0.9 3.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-FPG_IleRS PF06827.9 KRH93928.1 - 0.038 13.6 0.4 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KRH93928.1 - 0.06 13.3 1.9 6.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KRH93928.1 - 0.09 12.0 1.1 2.5 7.4 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Desulfoferrod_N PF06397.7 KRH93928.1 - 0.12 11.7 1.5 2 7.8 0.2 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF1179 PF06678.6 KRH93928.1 - 0.23 11.7 1.0 0.39 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) ADK_lid PF05191.9 KRH93928.1 - 1.1 8.9 4.6 9 6.0 0.0 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid TFIIE-A_C-term PF11521.3 KRH93928.1 - 1.2 9.1 4.8 1.9 8.4 0.0 2.2 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha TFIIS_C PF01096.13 KRH93928.1 - 3 7.5 7.8 6.2 6.5 0.1 2.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-LITAF-like PF10601.4 KRH93928.1 - 4.4 7.2 7.6 13 5.7 0.4 3.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain WD40 PF00400.27 KRH93929.1 - 2.9e-25 87.1 14.2 5.7e-07 29.1 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KRH93929.1 - 0.00037 18.7 0.4 0.011 13.9 0.0 2.8 2 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KRH93929.1 - 0.0037 16.7 0.0 0.027 13.9 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 KRH93929.1 - 0.0043 15.8 4.5 1.5 7.4 1.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 KRH93929.1 - 0.0067 14.7 0.0 0.037 12.2 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) ATP-synt_ab_N PF02874.18 KRH93929.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L14 PF00238.14 KRH93930.1 - 1.9e-33 114.8 0.0 2.2e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF3744 PF12558.3 KRH93931.1 - 0.049 14.0 1.3 0.38 11.2 0.1 2.6 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter DUF1202 PF06717.6 KRH93932.1 - 0.0034 16.6 0.1 0.004 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) DivIC PF04977.10 KRH93932.1 - 0.005 16.2 1.3 0.013 14.9 0.7 1.7 2 0 0 2 2 2 1 Septum formation initiator DUF2232 PF09991.4 KRH93932.1 - 0.12 11.3 1.7 0.2 10.6 0.5 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) LSM PF01423.17 KRH93933.1 - 4.6e-13 48.5 0.2 7e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain Pentapeptide_4 PF13599.1 KRH93933.1 - 0.036 13.8 0.1 0.062 13.1 0.0 1.4 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) SM-ATX PF14438.1 KRH93933.1 - 0.039 13.8 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.2 KRH93933.1 - 0.051 13.3 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain DUF273 PF03314.9 KRH93934.1 - 0.056 12.7 0.5 0.08 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 RasGEF PF00617.14 KRH93935.1 - 1.5e-08 34.6 1.0 2.5e-08 33.8 0.7 1.4 1 0 0 1 1 1 1 RasGEF domain HECT PF00632.20 KRH93937.1 - 7.2e-24 84.5 6.8 3e-22 79.1 4.7 2.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) T4_baseplate PF12322.3 KRH93939.1 - 0.0036 16.5 0.8 0.0044 16.2 0.5 1.3 1 0 0 1 1 1 1 T4 bacteriophage base plate protein zf-C4_Topoisom PF01396.14 KRH93939.1 - 0.013 15.0 1.5 0.028 13.9 1.1 1.6 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.11 KRH93939.1 - 0.021 14.4 1.7 0.13 11.9 1.2 2.0 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.5 KRH93939.1 - 0.091 12.7 0.2 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Zinc ribbon domain SOCS PF12610.3 KRH93939.1 - 0.091 13.0 0.2 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Suppressor of cytokine signalling PyrI_C PF02748.10 KRH93939.1 - 0.25 10.8 1.5 18 4.8 0.1 3.0 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rapamycin_bind PF08771.6 KRH93942.1 - 0.051 13.6 2.0 0.18 11.8 0.1 2.2 1 1 1 2 2 2 0 Rapamycin binding domain Vac_Fusion PF02346.11 KRH93942.1 - 0.13 11.7 0.3 3.8 6.9 0.1 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Antimicrobial19 PF08225.6 KRH93942.1 - 0.17 11.2 12.0 9.9 5.6 0.1 4.4 4 2 2 6 6 6 0 Pseudin antimicrobial peptide Amelogenin PF02948.10 KRH93942.1 - 1.1 9.8 11.0 1.4 9.5 7.6 1.2 1 0 0 1 1 1 0 Amelogenin XPC-binding PF09280.6 KRH93942.1 - 5.9 6.4 8.0 11 5.5 0.3 3.4 1 1 0 2 2 2 0 XPC-binding domain Nol1_Nop2_Fmu PF01189.12 KRH93945.1 - 5.9e-12 45.5 0.0 7.3e-11 41.9 0.0 2.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family BATS PF06968.8 KRH93945.1 - 0.019 14.8 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain GUCT PF08152.7 KRH93945.1 - 0.049 13.6 0.1 0.39 10.7 0.0 2.5 3 0 0 3 3 3 0 GUCT (NUC152) domain Radical_SAM PF04055.16 KRH93946.1 - 1.1e-17 64.7 0.1 3.4e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily DUF1399 PF07173.7 KRH93948.1 - 0.14 12.4 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) DASH_Dad3 PF08656.5 KRH93949.1 - 0.065 12.9 1.7 0.29 10.8 0.2 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 TMF_TATA_bd PF12325.3 KRH93949.1 - 0.79 9.4 9.4 3.4 7.4 0.4 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2779 PF11074.3 KRH93949.1 - 2.2 8.3 9.2 7.2 6.6 4.6 2.5 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) Peptidase_A4 PF01828.12 KRH93949.1 - 8.7 5.3 6.5 2.9 6.9 0.3 2.1 2 0 0 2 2 2 0 Peptidase A4 family MIP-T3 PF10243.4 KRH93950.1 - 0.12 10.8 54.4 0.19 10.1 37.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 KRH93950.1 - 0.55 8.4 41.0 1.1 7.4 28.4 1.4 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 KRH93950.1 - 1.1 7.3 57.5 1.8 6.6 39.8 1.4 1 0 0 1 1 1 0 Utp14 protein EphA2_TM PF14575.1 KRH93950.1 - 1.3 9.4 0.0 1.3 9.4 0.0 4.3 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain S-AdoMet_synt_M PF02772.11 KRH93951.1 - 2e-11 43.8 0.0 5.8e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 S-adenosylmethionine synthetase, central domain MoeA_C PF03454.10 KRH93951.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Rad60-SLD PF11976.3 KRH93953.1 - 3.5e-10 39.4 0.0 4.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_60s PF00428.14 KRH93954.1 - 1.1e-13 51.3 0.2 1.3e-13 51.1 0.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-C4H2 PF10146.4 KRH93954.1 - 0.01 15.8 0.0 0.011 15.7 0.0 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein His_Phos_2 PF00328.17 KRH93955.1 - 1.4e-12 47.6 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KRH93955.1 - 0.034 14.2 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Membr_traf_MHD PF10540.4 KRH93955.1 - 0.041 13.6 0.1 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain DUF2358 PF10184.4 KRH93955.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) rve PF00665.21 KRH93956.1 - 0.0038 17.3 0.1 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH93956.1 - 0.004 16.6 0.2 0.0054 16.2 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain DUF3932 PF13068.1 KRH93956.1 - 0.089 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) DDE_3 PF13358.1 KRH93957.1 - 1e-15 57.7 0.1 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 KRH93957.1 - 0.00041 20.4 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF3741 PF12552.3 KRH93957.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3741) DUF4047 PF13256.1 KRH93957.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) eIF3g PF12353.3 KRH93958.1 - 0.0026 17.6 1.4 0.0026 17.6 1.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G MU117 PF15474.1 KRH93958.1 - 0.019 15.4 2.2 0.057 13.9 0.4 2.1 2 0 0 2 2 2 0 Meiotically up-regulated gene family DUF2312 PF10073.4 KRH93959.1 - 0.017 14.4 1.1 0.049 12.9 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) WHEP-TRS PF00458.15 KRH93959.1 - 0.021 14.4 0.3 0.021 14.4 0.2 1.7 2 0 0 2 2 2 0 WHEP-TRS domain Toprim_Crpt PF13342.1 KRH93959.1 - 0.045 13.3 0.1 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase RVT_1 PF00078.22 KRH93960.1 - 2.9e-25 88.9 0.3 4.1e-25 88.3 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 KRH93961.1 - 0.012 15.4 0.2 0.05 13.3 0.1 2.1 2 1 0 2 2 2 0 Reverse transcriptase-like Vps16_C PF04840.7 KRH93961.1 - 0.019 13.9 0.6 2.4 7.0 0.1 2.1 1 1 1 2 2 2 0 Vps16, C-terminal region CobT PF06213.7 KRH93963.1 - 0.2 10.7 19.7 0.4 9.7 13.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YbjQ_1 PF01906.12 KRH93963.1 - 0.31 11.4 2.1 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative heavy-metal-binding Raftlin PF15250.1 KRH93963.1 - 0.49 8.8 14.5 0.35 9.3 5.4 2.2 2 0 0 2 2 2 0 Raftlin Hid1 PF12722.2 KRH93963.1 - 6.7 4.2 12.2 9 3.8 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RVT_1 PF00078.22 KRH93964.1 - 1e-24 87.0 0.2 2e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH93964.1 - 0.00011 21.9 0.2 0.00011 21.9 0.1 1.8 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.1 KRH93964.1 - 0.0062 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF2250 PF10007.4 KRH93964.1 - 0.1 12.4 1.9 19 5.2 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) rve PF00665.21 KRH93965.1 - 1.5e-14 54.1 0.2 4.8e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF2493 PF10686.4 KRH93965.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Stirrup PF09061.1 KRH93965.1 - 0.25 11.2 2.4 11 6.0 0.1 2.9 2 0 0 2 2 2 0 Stirrup DUF424 PF04242.8 KRH93967.1 - 0.0098 15.9 0.9 0.16 12.0 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF424) DUF3802 PF12290.3 KRH93969.1 - 0.00073 19.8 1.9 0.0017 18.6 0.6 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3802) UvsY PF11056.3 KRH93969.1 - 0.0083 16.2 1.8 0.013 15.6 1.2 1.5 1 0 0 1 1 1 1 Recombination, repair and ssDNA binding protein UvsY XhlA PF10779.4 KRH93969.1 - 0.0091 15.8 1.4 0.0091 15.8 1.0 3.0 3 0 0 3 3 3 1 Haemolysin XhlA Lzipper-MIP1 PF14389.1 KRH93969.1 - 0.064 13.3 2.0 0.13 12.3 1.3 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1878 PF08963.5 KRH93969.1 - 0.082 13.1 4.3 1.3 9.2 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) DUF2779 PF11074.3 KRH93969.1 - 1.1 9.3 5.9 2.3 8.2 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) Syntaxin-6_N PF09177.6 KRH93969.1 - 1.3 9.5 4.7 2.4 8.6 0.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATP-synt_C PF00137.16 KRH93971.1 - 7.5e-12 44.9 15.7 1.6e-06 27.8 0.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C GIDA PF01134.17 KRH93971.1 - 0.084 11.7 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2838 PF10998.3 KRH93971.1 - 0.18 11.6 5.6 0.039 13.8 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2838) Rota_NSP4 PF01452.11 KRH93971.1 - 0.62 9.3 2.6 1.1 8.5 0.1 2.4 2 1 1 3 3 3 0 Rotavirus non structural protein DUF1546 PF07571.8 KRH93973.1 - 0.021 14.9 0.2 0.062 13.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) Asp-B-Hydro_N PF05279.6 KRH93973.1 - 4.7 6.9 17.5 8.2 6.2 12.1 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_M17 PF00883.16 KRH93974.1 - 1.9e-98 329.2 0.0 1.3e-81 273.8 0.0 2.1 2 0 0 2 2 2 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KRH93974.1 - 0.0033 17.1 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Imm-NTF2-2 PF15631.1 KRH93975.1 - 0.017 15.0 0.6 0.025 14.5 0.1 1.5 2 0 0 2 2 2 0 NTF2 fold immunity protein IN_DBD_C PF00552.16 KRH93975.1 - 0.1 12.0 0.2 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 Integrase DNA binding domain PilJ PF13675.1 KRH93976.1 - 0.0011 19.2 6.4 0.27 11.5 0.4 4.2 1 1 2 4 4 4 3 Type IV pili methyl-accepting chemotaxis transducer N-term Hpt PF01627.18 KRH93976.1 - 0.0047 16.9 4.7 15 5.6 0.1 4.7 1 1 2 4 4 4 1 Hpt domain DUF883 PF05957.8 KRH93976.1 - 0.027 14.8 22.2 5.5 7.4 0.4 5.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF883) HEAT_EZ PF13513.1 KRH93976.1 - 0.093 13.2 5.1 1.3e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat Calici_coat_C PF08435.6 KRH93976.1 - 0.58 9.4 4.4 0.29 10.3 0.5 2.1 1 1 1 2 2 2 0 Calicivirus coat protein C-terminal BIV_Env PF05858.7 KRH93976.1 - 1.4 6.8 5.0 2.4 6.0 3.5 1.5 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) PAH PF02671.16 KRH93976.1 - 1.8 8.2 9.8 77 3.0 0.1 5.4 5 0 0 5 5 5 0 Paired amphipathic helix repeat DUF1569 PF07606.6 KRH93978.1 - 0.029 14.2 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) DUF1179 PF06678.6 KRH93979.1 - 0.14 12.5 1.4 0.29 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DUF1512 PF07431.7 KRH93980.1 - 0.017 13.8 8.6 0.02 13.6 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF2500 PF10694.4 KRH93980.1 - 0.12 12.3 3.4 6.6 6.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Peptidase_M48 PF01435.13 KRH93983.1 - 1.1e-41 142.8 0.1 1.8e-41 142.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.4 KRH93983.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF2456 PF10445.4 KRH93983.1 - 0.21 11.5 11.3 1.4 8.8 0.5 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2456) DUF4538 PF15061.1 KRH93983.1 - 0.25 10.6 3.1 0.35 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Pkinase PF00069.20 KRH93984.1 - 9.2e-64 215.0 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH93984.1 - 2.7e-34 118.4 0.0 3.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH93984.1 - 2.4e-05 23.4 0.0 4.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KRH93984.1 - 0.079 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3227 PF11537.3 KRH93984.1 - 0.094 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Flp_N PF03930.9 KRH93985.1 - 0.095 12.4 5.3 2.9 7.7 1.0 2.9 3 1 0 3 3 3 0 Recombinase Flp protein N-terminus Ras PF00071.17 KRH93987.1 - 2.4e-41 140.8 0.1 2.9e-41 140.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH93987.1 - 6.1e-16 58.9 0.1 1.2e-15 58.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KRH93987.1 - 2.1e-09 36.8 0.1 2.3e-09 36.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KRH93987.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KRH93987.1 - 0.0036 17.4 0.1 4.2 7.5 0.0 2.8 2 1 1 3 3 3 2 AAA domain SRPRB PF09439.5 KRH93987.1 - 0.0053 15.9 0.2 0.0065 15.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KRH93987.1 - 0.0066 16.3 0.7 0.027 14.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain DUF1027 PF06265.6 KRH93987.1 - 0.12 12.2 2.7 0.25 11.2 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) AAA_24 PF13479.1 KRH93987.1 - 0.14 11.7 0.9 4 6.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain YEATS PF03366.11 KRH93988.1 - 1.7e-17 62.9 0.6 6.1e-17 61.1 0.4 1.9 1 0 0 1 1 1 1 YEATS family MutS_V PF00488.16 KRH93991.1 - 1.9e-50 171.4 1.5 3.4e-26 92.1 0.1 2.7 2 0 0 2 2 2 2 MutS domain V MutS_I PF01624.15 KRH93991.1 - 7e-29 100.1 0.1 2.4e-28 98.4 0.1 2.0 1 1 0 1 1 1 1 MutS domain I MutS_III PF05192.13 KRH93991.1 - 5.6e-09 36.0 3.1 8.6e-09 35.4 0.6 2.6 2 1 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 KRH93991.1 - 0.00067 19.1 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvA_N PF01330.16 KRH93992.1 - 0.0054 16.5 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 RuvA N terminal domain TIP49 PF06068.8 KRH93994.1 - 3.2e-13 49.1 7.5 4e-07 29.0 1.8 3.9 1 1 2 3 3 3 3 TIP49 C-terminus AAA_22 PF13401.1 KRH93994.1 - 0.00023 21.2 0.1 0.11 12.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KRH93994.1 - 0.0082 15.5 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KRH93994.1 - 0.014 15.2 4.9 0.13 12.1 0.0 3.5 2 2 2 4 4 4 0 AAA domain AAA PF00004.24 KRH93994.1 - 0.05 13.7 2.1 0.1 12.8 0.1 2.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) NuA4 PF09340.5 KRH93996.1 - 4.6e-11 42.2 0.6 6.2e-11 41.7 0.4 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RNA_pol_L_2 PF13656.1 KRH93997.1 - 2.2e-13 49.4 0.4 1e-11 44.0 0.3 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain C2 PF00168.25 KRH93998.1 - 9.1e-22 76.7 2.3 3.6e-15 55.5 0.1 3.5 2 1 0 2 2 2 2 C2 domain DUF2404 PF10296.4 KRH93998.1 - 0.0025 17.8 0.0 0.11 12.6 0.0 2.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) MDFI PF15316.1 KRH93999.1 - 0.0084 16.1 0.2 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 MyoD family inhibitor Podoplanin PF05808.6 KRH93999.1 - 0.018 14.6 1.5 0.024 14.1 1.0 1.3 1 0 0 1 1 1 0 Podoplanin Sec3_C PF09763.4 KRH93999.1 - 0.038 12.1 0.9 0.041 12.0 0.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 ETRAMP PF09716.5 KRH93999.1 - 0.039 13.9 1.0 0.064 13.2 0.8 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Apt1 PF10351.4 KRH93999.1 - 0.24 10.2 6.9 0.27 10.0 4.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.12 KRH93999.1 - 0.3 10.8 4.5 0.37 10.5 3.1 1.1 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.9 KRH93999.1 - 0.38 10.7 4.6 0.56 10.2 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.3 KRH93999.1 - 1.5 7.2 5.0 2.1 6.8 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hamartin PF04388.7 KRH93999.1 - 1.7 7.2 7.4 1.7 7.1 5.1 1.0 1 0 0 1 1 1 0 Hamartin protein Bindin PF02084.10 KRH93999.1 - 2.4 8.1 6.6 1.4 8.8 3.4 1.4 1 1 0 1 1 1 0 Bindin Macoilin PF09726.4 KRH93999.1 - 2.9 6.0 8.7 3.5 5.7 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 KRH93999.1 - 4 7.1 12.3 5.8 6.6 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF2413 PF10310.4 KRH93999.1 - 4.8 5.8 10.3 6.4 5.4 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3827 PF12877.2 KRH93999.1 - 7.9 4.4 8.1 10 4.0 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Herpes_capsid PF06112.6 KRH93999.1 - 8.5 6.4 14.0 13 5.7 9.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein UCH PF00443.24 KRH94000.1 - 1.6e-06 27.4 0.8 0.00026 20.1 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RasGAP_C PF03836.10 KRH94001.1 - 0.0023 17.6 14.8 0.0023 17.6 10.2 4.5 3 2 2 5 5 5 1 RasGAP C-terminus KIAA1430 PF13879.1 KRH94002.1 - 0.0012 19.2 6.5 0.0013 19.0 4.5 1.1 1 0 0 1 1 1 1 KIAA1430 homologue Retrotrans_gag PF03732.12 KRH94004.1 - 0.023 14.7 0.1 0.93 9.6 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon gag protein GvpO PF05800.6 KRH94004.1 - 0.067 13.0 0.7 4.6 7.1 0.0 2.0 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO SNF2_N PF00176.18 KRH94006.1 - 2.2e-24 85.8 0.1 2.2e-24 85.8 0.1 3.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain HEAT PF02985.17 KRH94006.1 - 0.019 14.9 0.1 3.6 7.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat DUF843 PF05814.6 KRH94007.1 - 0.012 15.4 3.6 0.012 15.4 2.5 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) FA_desaturase PF00487.19 KRH94007.1 - 0.076 12.4 2.9 0.11 11.9 2.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Peptidase_M56 PF05569.6 KRH94007.1 - 0.34 9.8 12.0 0.3 9.9 4.3 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 PDR_CDR PF06422.7 KRH94007.1 - 2.7 7.7 4.6 1.3 8.7 0.3 2.2 2 0 0 2 2 2 0 CDR ABC transporter ABC_tran PF00005.22 KRH94009.1 - 2.5e-07 31.0 0.0 6.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KRH94009.1 - 6.8e-06 26.2 0.1 6.8e-06 26.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain ABC2_membrane PF01061.19 KRH94009.1 - 0.00052 19.2 18.4 0.00052 19.2 12.7 3.1 2 1 1 3 3 3 1 ABC-2 type transporter SMC_N PF02463.14 KRH94009.1 - 0.0081 15.4 0.0 0.027 13.7 0.0 1.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 KRH94009.1 - 0.015 15.2 0.0 0.058 13.3 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 KRH94010.1 - 1.3e-13 51.4 0.0 1.8e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KRH94010.1 - 6.7e-05 22.1 0.1 8.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KRH94010.1 - 9.4e-05 22.4 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KRH94010.1 - 0.00014 22.7 0.0 0.0002 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KRH94010.1 - 0.00071 19.6 1.0 0.0011 19.0 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KRH94010.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KRH94010.1 - 0.0016 17.4 0.1 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 KRH94010.1 - 0.0018 18.5 0.3 0.0029 17.9 0.2 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KRH94010.1 - 0.0018 18.0 0.2 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 NTPase MMR_HSR1 PF01926.18 KRH94010.1 - 0.0028 17.6 0.2 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KRH94010.1 - 0.003 17.2 0.3 0.0046 16.6 0.2 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 KRH94010.1 - 0.0033 17.5 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KRH94010.1 - 0.0062 16.5 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KRH94010.1 - 0.007 15.8 1.0 0.014 14.9 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 KRH94010.1 - 0.008 15.6 1.1 0.012 15.0 0.8 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KRH94010.1 - 0.008 16.5 4.6 0.013 15.8 2.5 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KRH94010.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KRH94010.1 - 0.01 14.8 0.1 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 Septin Arch_ATPase PF01637.13 KRH94010.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KRH94010.1 - 0.01 15.2 0.5 0.015 14.7 0.4 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KRH94010.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KRH94010.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KRH94010.1 - 0.014 14.9 0.6 0.029 13.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KRH94010.1 - 0.015 14.9 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KRH94010.1 - 0.016 15.0 0.1 0.025 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KRH94010.1 - 0.017 14.2 0.7 0.019 13.9 0.5 1.2 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 KRH94010.1 - 0.021 14.5 0.2 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 KRH94010.1 - 0.021 13.8 0.1 0.03 13.3 0.1 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ATP_bind_1 PF03029.12 KRH94010.1 - 0.023 14.2 0.5 0.034 13.6 0.3 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 KRH94010.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 KRH94010.1 - 0.034 13.8 0.1 0.096 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PIF1 PF05970.9 KRH94010.1 - 0.037 12.9 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Pox_A32 PF04665.7 KRH94010.1 - 0.041 13.1 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 KRH94010.1 - 0.047 13.1 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad17 PF03215.10 KRH94010.1 - 0.077 11.6 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KRH94010.1 - 0.086 11.6 0.4 0.19 10.5 0.1 1.7 1 1 1 2 2 2 0 NB-ARC domain SMC_N PF02463.14 KRH94010.1 - 0.093 11.9 0.2 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 KRH94010.1 - 0.095 12.1 0.3 0.2 11.0 0.2 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 KRH94010.1 - 0.097 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain PRK PF00485.13 KRH94010.1 - 0.098 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 KRH94010.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KRH94010.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Cu_amine_oxidN3 PF02728.11 KRH94013.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain DUF3087 PF11286.3 KRH94016.1 - 0.074 12.2 0.1 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) FadA PF09403.5 KRH94016.1 - 0.1 12.5 1.9 0.13 12.2 1.3 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Nucleic_acid_bd PF13820.1 KRH94016.1 - 0.12 11.9 0.6 0.16 11.5 0.4 1.2 1 0 0 1 1 1 0 Putative nucleic acid-binding region U1snRNP70_N PF12220.3 KRH94016.1 - 0.13 12.5 3.4 0.18 12.1 2.3 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ETRAMP PF09716.5 KRH94016.1 - 0.67 9.9 3.2 3.4 7.6 2.2 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MIF4G_like_2 PF09090.6 KRH94019.1 - 0.0034 16.6 4.7 0.0036 16.5 3.3 1.0 1 0 0 1 1 1 1 MIF4G like Kinesin-related PF06548.6 KRH94019.1 - 0.004 15.7 3.8 0.0046 15.5 2.7 1.0 1 0 0 1 1 1 1 Kinesin-related zf-C4H2 PF10146.4 KRH94019.1 - 0.02 14.9 3.2 0.024 14.6 2.2 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Baculo_IE-1 PF05290.6 KRH94019.1 - 0.025 14.2 1.5 0.037 13.7 0.8 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1342 PF07072.6 KRH94019.1 - 0.027 14.1 3.2 0.032 13.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) COG2 PF06148.6 KRH94019.1 - 0.035 13.9 4.9 0.69 9.7 3.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3375 PF11855.3 KRH94019.1 - 0.035 12.8 0.2 0.038 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) CK2S PF15011.1 KRH94019.1 - 0.04 13.7 1.0 0.053 13.3 0.6 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate FerA PF08165.6 KRH94019.1 - 0.043 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 FerA (NUC095) domain Nsp1_C PF05064.8 KRH94019.1 - 0.051 13.2 4.3 0.07 12.7 3.0 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region SYCE1 PF15233.1 KRH94019.1 - 0.051 13.4 3.5 0.067 13.1 2.4 1.1 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 GatB_Yqey PF02637.13 KRH94019.1 - 0.16 11.6 3.3 0.22 11.2 2.3 1.2 1 0 0 1 1 1 0 GatB domain LON PF02190.11 KRH94019.1 - 0.17 11.5 3.7 0.21 11.2 2.6 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF3557 PF12078.3 KRH94019.1 - 0.24 11.1 4.3 0.28 10.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) HrcA PF01628.16 KRH94019.1 - 0.34 10.4 3.0 0.41 10.1 2.1 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain KxDL PF10241.4 KRH94019.1 - 0.38 10.6 3.6 0.65 9.9 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein TetR_C_4 PF08359.6 KRH94019.1 - 0.48 10.3 3.8 2.5 8.0 0.3 2.0 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region DUF1759 PF03564.10 KRH94019.1 - 0.59 9.9 4.4 0.7 9.7 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) YMF19 PF02326.10 KRH94019.1 - 1.1 9.8 4.5 0.82 10.2 1.4 1.8 1 1 1 2 2 2 0 Plant ATP synthase F0 RNA_pol_Rpc34 PF05158.7 KRH94020.1 - 4e-23 82.1 14.5 5.2e-23 81.7 10.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit ESCRT-II PF05871.7 KRH94020.1 - 8.9e-05 22.4 6.3 0.016 15.1 0.0 3.4 1 1 2 3 3 3 2 ESCRT-II complex subunit HxlR PF01638.12 KRH94020.1 - 0.00033 20.2 2.6 0.082 12.5 0.1 2.5 2 0 0 2 2 2 2 HxlR-like helix-turn-helix MarR PF01047.17 KRH94020.1 - 0.0069 16.0 0.7 0.52 10.0 0.0 2.6 2 0 0 2 2 2 1 MarR family RPA_C PF08784.6 KRH94020.1 - 0.016 15.6 0.2 0.23 11.9 0.1 2.5 2 1 1 3 3 3 0 Replication protein A C terminal HTH_34 PF13601.1 KRH94020.1 - 0.017 15.1 2.1 0.25 11.4 0.4 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.15 KRH94020.1 - 0.035 14.2 0.2 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator z-alpha PF02295.12 KRH94020.1 - 0.073 12.8 6.0 0.29 10.9 0.2 3.5 3 1 0 3 3 3 0 Adenosine deaminase z-alpha domain DUF2286 PF10051.4 KRH94020.1 - 0.28 10.8 5.1 0.71 9.5 3.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) Sulfolobus_pRN PF05584.6 KRH94020.1 - 3.2 7.7 7.8 18 5.3 0.1 3.1 2 1 0 3 3 3 0 Sulfolobus plasmid regulatory protein FAM110_C PF14160.1 KRH94021.1 - 2.9 8.8 7.0 0.53 11.2 1.7 2.0 2 1 0 2 2 2 0 Centrosome-associated C terminus Trehalase PF01204.13 KRH94022.1 - 1.1e-123 413.5 1.2 1.2e-121 406.8 0.5 2.3 1 1 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 KRH94022.1 - 0.078 11.1 0.0 0.14 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase MS_channel PF00924.13 KRH94024.1 - 2.8e-06 26.7 1.8 1.4e-05 24.5 1.2 2.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KRH94024.1 - 0.00078 18.5 0.2 0.0043 16.2 0.1 2.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KRH94024.1 - 0.0097 15.7 3.7 0.011 15.5 0.5 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KRH94024.1 - 0.059 13.0 0.8 0.23 11.1 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair Glutaredoxin PF00462.19 KRH94026.1 - 3.8e-10 39.6 0.0 5.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KRH94026.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KRH94026.1 - 0.0081 15.7 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2318 PF10080.4 KRH94026.1 - 0.027 14.2 0.2 0.097 12.4 0.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) FANCL_C PF11793.3 KRH94026.1 - 0.052 13.5 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain TypeIII_RM_meth PF12564.3 KRH94031.1 - 0.084 12.8 0.3 0.46 10.5 0.0 2.0 1 1 1 2 2 2 0 Type III restriction/modification enzyme methylation subunit EXOSC1 PF10447.4 KRH94033.1 - 0.0015 18.4 0.9 0.046 13.6 0.4 3.0 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 DNA_primase_S PF01896.14 KRH94035.1 - 6.5e-18 64.9 5.0 1.7e-10 40.9 0.1 2.9 2 1 1 3 3 3 2 Eukaryotic and archaeal DNA primase small subunit PAP_assoc PF03828.14 KRH94035.1 - 0.081 12.8 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase Per1 PF04080.8 KRH94036.1 - 7e-11 42.0 12.6 4.2e-07 29.6 2.3 2.4 1 1 1 2 2 2 2 Per1-like Ribosomal_S19 PF00203.16 KRH94038.1 - 2.4e-14 52.6 0.1 3.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3551 PF12071.3 KRH94038.1 - 0.014 14.9 0.4 0.034 13.6 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3551) Tox-REase-9 PF15650.1 KRH94038.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 Adap_comp_sub PF00928.16 KRH94039.1 - 1e-05 24.7 0.1 1.7e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DUF1014 PF06244.7 KRH94040.1 - 1e-07 32.1 21.3 0.18 12.0 0.6 4.5 1 1 4 5 5 5 4 Protein of unknown function (DUF1014) Ribosomal_L30 PF00327.15 KRH94040.1 - 0.019 14.5 0.0 1.3e+02 2.2 0.0 4.0 4 0 0 4 4 4 0 Ribosomal protein L30p/L7e DUF161 PF02588.10 KRH94040.1 - 0.29 11.4 3.0 0.41 10.9 2.1 1.2 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 MbeB_N PF04837.7 KRH94040.1 - 0.54 10.4 19.1 18 5.5 0.4 4.8 4 0 0 4 4 4 0 MbeB-like, N-term conserved region Maelstrom PF13017.1 KRH94040.1 - 1.1 8.7 12.0 3.2 7.1 2.0 2.2 1 1 1 2 2 2 0 piRNA pathway germ-plasm component PFO_beta_C PF12367.3 KRH94040.1 - 2.5 8.0 6.7 1.3e+02 2.6 0.1 3.9 1 1 3 4 4 4 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal TMA7 PF09072.5 KRH94040.1 - 3.2 8.2 21.8 24 5.5 1.6 4.2 1 1 3 4 4 4 0 Translation machinery associated TMA7 DDE_Tnp_IS1595 PF12762.2 KRH94042.1 - 6.3e-27 94.2 0.2 8e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Corona_RPol_N PF06478.8 KRH94042.1 - 0.0031 16.2 0.2 0.0038 15.9 0.1 1.1 1 0 0 1 1 1 1 Coronavirus RPol N-terminus PUF PF00806.14 KRH94043.1 - 0.0061 15.9 0.2 0.013 14.9 0.2 1.6 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat zf-C4_Topoisom PF01396.14 KRH94043.1 - 0.016 14.6 4.3 0.044 13.2 3.0 1.8 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.1 KRH94043.1 - 0.042 14.0 2.3 0.042 14.0 1.6 1.5 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.11 KRH94043.1 - 0.13 11.9 3.8 0.25 11.0 2.6 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DDE_Tnp_IS1595 PF12762.2 KRH94045.1 - 4e-05 23.4 0.0 4.4e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 KRH94047.1 - 3.4e-15 56.2 0.1 1.1e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 KRH94047.1 - 0.073 12.7 0.3 0.27 10.9 0.2 2.0 1 0 0 1 1 1 0 GAG-pre-integrase domain Cript PF10235.4 KRH94047.1 - 0.34 11.2 3.8 0.43 10.9 0.1 2.4 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT DDE_Tnp_4 PF13359.1 KRH94048.1 - 2.8e-17 62.7 0.7 5.3e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.9 KRH94048.1 - 6.8e-05 22.3 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein SpoIIID PF12116.3 KRH94048.1 - 0.00027 20.8 0.1 0.00071 19.4 0.1 1.7 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_28 PF13518.1 KRH94048.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Trp_repressor PF01371.14 KRH94048.1 - 0.024 14.5 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Trp repressor protein VHP PF02209.14 KRH94048.1 - 0.047 13.3 0.3 0.31 10.7 0.0 2.6 2 0 0 2 2 2 0 Villin headpiece domain HTH_Tnp_1 PF01527.15 KRH94048.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_Tnp_4 PF13613.1 KRH94048.1 - 0.099 12.1 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Prolamin_like PF05617.6 KRH94048.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolamin-like Myb_DNA-bind_4 PF13837.1 KRH94049.1 - 0.0017 18.4 5.7 0.0017 18.4 3.9 2.7 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KRH94049.1 - 0.0027 17.8 1.2 0.0027 17.8 0.8 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like PNPase PF03726.9 KRH94049.1 - 0.0072 16.5 4.0 0.0083 16.3 1.4 2.2 1 1 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4083 PF13314.1 KRH94049.1 - 0.07 12.9 0.9 0.07 12.9 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) IBP39 PF11422.3 KRH94050.1 - 0.082 12.4 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Ribosomal_L30 PF00327.15 KRH94053.1 - 4.9e-13 48.4 0.6 9.4e-13 47.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF1355 PF07090.6 KRH94053.1 - 0.027 13.8 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1355) MotCF PF09158.5 KRH94053.1 - 1.4 8.6 8.6 0.85 9.3 0.6 2.6 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal DnaJ PF00226.26 KRH94055.1 - 4.5e-12 45.5 0.9 4.5e-12 45.5 0.6 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 KRH94055.1 - 7.3e-05 23.0 0.3 2.6 8.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4363 PF14276.1 KRH94055.1 - 0.023 14.3 0.4 0.023 14.3 0.3 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4363) DLD PF14878.1 KRH94055.1 - 6.5 6.9 15.0 0.71 9.9 0.8 3.5 3 0 0 3 3 3 0 Death-like domain of SPT6 AT_hook PF02178.14 KRH94056.1 - 0.037 13.6 3.0 0.11 12.2 2.1 1.8 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.22 KRH94057.1 - 3.6e-25 88.8 0.1 7e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KRH94057.1 - 5.1e-09 35.6 0.1 9.5e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KRH94057.1 - 1.6e-06 28.2 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KRH94057.1 - 3.6e-05 23.8 1.0 3.6e-05 23.8 0.7 3.7 3 2 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KRH94057.1 - 0.00025 21.0 0.0 0.00064 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KRH94057.1 - 0.0007 19.3 1.7 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 KRH94057.1 - 0.0013 17.6 0.2 0.0026 16.7 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 KRH94057.1 - 0.0013 18.1 0.3 0.0036 16.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KRH94057.1 - 0.0026 17.1 0.0 0.0089 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KRH94057.1 - 0.0033 16.9 1.8 0.074 12.4 0.7 2.5 2 0 0 2 2 2 1 AAA-like domain SbcCD_C PF13558.1 KRH94057.1 - 0.0044 16.9 0.0 0.055 13.3 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KRH94057.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KRH94057.1 - 0.011 16.4 0.0 0.029 15.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KRH94057.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.18 KRH94057.1 - 0.012 15.4 0.1 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.1 KRH94057.1 - 0.014 15.7 3.2 0.024 14.9 0.8 2.6 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KRH94057.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 KRH94057.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KRH94057.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KRH94057.1 - 0.082 12.7 0.0 0.27 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KRH94057.1 - 0.096 12.8 1.1 1.1 9.4 0.8 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KRH94057.1 - 0.13 12.2 0.6 0.43 10.5 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KRH94057.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KRH94057.1 - 0.15 11.4 0.3 0.28 10.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.19 KRH94057.1 - 0.17 11.0 27.3 0.016 14.3 15.2 2.0 2 1 0 2 2 2 0 ABC-2 type transporter AAA_30 PF13604.1 KRH94057.1 - 0.39 10.2 0.7 0.66 9.5 0.5 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KRH94057.1 - 3.7 7.3 6.8 4.3 7.0 0.3 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 Leu_zip PF15294.1 KRH94058.1 - 0.021 13.9 11.0 0.03 13.4 7.6 1.2 1 0 0 1 1 1 0 Leucine zipper UpxZ PF06603.6 KRH94058.1 - 0.053 13.5 1.2 0.11 12.5 0.5 1.7 1 1 1 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Orthopox_A36R PF05950.6 KRH94058.1 - 0.09 12.6 0.6 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein PA26 PF04636.8 KRH94058.1 - 0.095 11.3 3.7 0.1 11.2 2.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Chitin_synth_1 PF01644.12 KRH94058.1 - 0.15 11.7 2.3 0.14 11.9 0.7 1.6 1 1 0 1 1 1 0 Chitin synthase CENP-H PF05837.7 KRH94058.1 - 1.8 8.7 8.9 3.1 8.0 6.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DASH_Dad3 PF08656.5 KRH94058.1 - 2.3 8.0 7.7 5.1 6.8 4.5 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF3166 PF11365.3 KRH94058.1 - 2.4 8.6 8.9 0.32 11.4 3.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) TAFII55_N PF04658.8 KRH94059.1 - 9.8e-23 80.4 0.5 9.8e-23 80.4 0.3 2.7 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF1451 PF07295.6 KRH94059.1 - 0.1 12.3 4.7 0.23 11.2 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) RbsD_FucU PF05025.8 KRH94059.1 - 0.28 11.4 3.0 0.42 10.9 1.7 1.6 1 1 0 1 1 1 0 RbsD / FucU transport protein family DUF1018 PF06252.7 KRH94059.1 - 0.31 11.5 4.4 2.5 8.6 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1018) YtzH PF14165.1 KRH94059.1 - 0.75 10.0 9.0 0.33 11.1 0.7 2.9 2 1 0 3 3 3 0 YtzH-like protein ALMT PF11744.3 KRH94059.1 - 1.3 7.6 5.3 1.8 7.1 3.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CBF PF03914.12 KRH94060.1 - 3.3 7.1 9.9 7.3 6.0 0.1 3.6 3 1 1 4 4 4 0 CBF/Mak21 family Collagen PF01391.13 KRH94061.1 - 7.5e-05 22.2 6.1 7.5e-05 22.2 4.2 2.2 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) HA2 PF04408.18 KRH94062.1 - 8e-17 61.1 0.2 2.4e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KRH94062.1 - 7.4e-16 57.9 0.1 2.6e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KRH94062.1 - 7.2e-13 48.2 0.0 1.8e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KRH94062.1 - 9.8e-05 21.9 1.9 0.00049 19.6 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.1 KRH94062.1 - 0.00037 20.3 0.4 0.0034 17.2 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KRH94062.1 - 0.0018 17.9 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KRH94062.1 - 0.0032 17.3 0.4 0.0032 17.3 0.2 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KRH94062.1 - 0.0047 17.0 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 KRH94062.1 - 0.007 16.0 0.0 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 Helicase T2SE PF00437.15 KRH94062.1 - 0.038 12.8 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KRH94062.1 - 0.072 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KRH94062.1 - 0.15 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain EF-hand_2 PF09068.6 KRH94062.1 - 0.32 11.0 4.1 0.44 10.6 0.2 2.8 2 1 0 2 2 2 0 EF hand DNA_Packaging_2 PF11123.3 KRH94063.1 - 0.11 12.3 1.1 1.4 8.8 0.1 2.1 1 1 0 2 2 2 0 DNA packaging protein Homeobox_KN PF05920.6 KRH94064.1 - 4e-16 58.4 0.4 8.5e-16 57.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KRH94064.1 - 3.4e-08 32.9 0.9 3.4e-08 32.9 0.6 2.4 2 1 0 2 2 2 1 Homeobox domain Sec34 PF04136.10 KRH94064.1 - 0.02 14.6 3.0 0.036 13.7 2.1 1.5 1 0 0 1 1 1 0 Sec34-like family Herpes_UL14 PF03580.9 KRH94064.1 - 0.11 12.3 3.2 0.21 11.3 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein IncA PF04156.9 KRH94064.1 - 2.2 7.8 9.4 3.3 7.2 6.5 1.4 1 1 0 1 1 1 0 IncA protein Wbp11 PF09429.5 KRH94064.1 - 5.5 7.0 7.7 7.5 6.6 0.2 2.7 3 0 0 3 3 3 0 WW domain binding protein 11 Homeobox PF00046.24 KRH94065.1 - 4.3e-15 55.0 0.4 1.5e-14 53.3 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH94065.1 - 3.8e-10 39.3 0.1 3.8e-10 39.3 0.1 2.3 3 1 0 3 3 3 1 Homeobox KN domain DUF2963 PF11178.3 KRH94065.1 - 0.0025 17.2 0.1 0.009 15.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2963) DUF4456 PF14644.1 KRH94065.1 - 0.0077 15.4 1.1 0.013 14.7 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF1415 PF07209.7 KRH94065.1 - 0.024 14.3 0.0 0.036 13.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1415) Vasculin PF15337.1 KRH94065.1 - 0.025 15.0 4.2 0.9 10.0 0.2 2.5 1 1 2 3 3 3 0 Vascular protein family Vasculin-like 1 Homez PF11569.3 KRH94065.1 - 0.045 12.8 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Herpes_UL36 PF03586.8 KRH94065.1 - 0.093 11.8 0.1 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 Herpesvirus UL36 tegument protein DDE_3 PF13358.1 KRH94066.1 - 2e-07 30.8 0.5 1.3e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Phage_min_cap2 PF06152.6 KRH94066.1 - 0.02 13.9 0.0 0.025 13.5 0.0 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 NPH3 PF03000.9 KRH94066.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 NPH3 family Autophagy_Cterm PF10381.4 KRH94066.1 - 0.66 9.1 6.2 1.3 8.2 4.3 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal RNA_pol_Rpb4 PF03874.11 KRH94067.1 - 0.032 14.2 1.5 0.057 13.4 1.0 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 Ribosomal_L29e PF01779.12 KRH94068.1 - 1.1e-11 44.4 4.1 1.1e-11 44.4 2.8 2.0 2 0 0 2 2 2 1 Ribosomal L29e protein family DUF217 PF02697.9 KRH94069.1 - 3.2 8.0 5.9 98 3.3 4.1 3.0 1 1 0 1 1 1 0 Uncharacterized ACR, COG1753 RNA_pol_I_A49 PF06870.7 KRH94070.1 - 1.1e-10 40.6 8.3 2.6e-05 22.9 0.9 2.1 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor B5 PF03484.10 KRH94070.1 - 0.085 12.6 0.2 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase B5 domain Ribosomal_S27e PF01667.12 KRH94071.1 - 3.3e-15 55.3 1.2 4.1e-15 55.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 SIR2 PF02146.12 KRH94071.1 - 0.018 14.8 0.4 0.018 14.8 0.3 1.1 1 0 0 1 1 1 0 Sir2 family Zn_Tnp_IS91 PF14319.1 KRH94071.1 - 0.046 13.2 3.5 0.055 12.9 2.4 1.2 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-LSD1 PF06943.7 KRH94071.1 - 0.069 12.7 3.8 2.4 7.8 0.0 2.6 3 0 0 3 3 3 0 LSD1 zinc finger Zn_Tnp_IS1595 PF12760.2 KRH94071.1 - 0.11 12.3 5.7 0.19 11.5 3.9 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C5HC2 PF02928.11 KRH94071.1 - 0.12 12.4 3.7 0.19 11.8 2.6 1.2 1 0 0 1 1 1 0 C5HC2 zinc finger DUF1451 PF07295.6 KRH94071.1 - 0.28 10.9 3.1 0.4 10.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Med22 PF06179.7 KRH94073.1 - 0.16 12.0 5.1 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex DS PF01916.12 KRH94074.1 - 1.2e-29 103.4 1.4 1.3e-14 54.0 0.2 3.8 2 1 1 3 3 3 3 Deoxyhypusine synthase RNase_HII PF01351.13 KRH94075.1 - 3.2e-21 75.8 0.4 5.4e-18 65.3 0.2 2.9 2 1 0 2 2 2 1 Ribonuclease HII PFK PF00365.15 KRH94076.1 - 6.9e-58 195.8 0.2 6.3e-34 117.2 0.2 3.2 3 0 0 3 3 3 3 Phosphofructokinase Ribosomal_S20p PF01649.13 KRH94076.1 - 0.36 11.2 5.6 6.1 7.2 0.3 4.0 4 0 0 4 4 4 0 Ribosomal protein S20 HLH PF00010.21 KRH94079.1 - 0.0027 17.3 0.5 0.0074 15.9 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S14 PF00253.16 KRH94080.1 - 1.6e-15 56.1 6.2 1.9e-15 55.9 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S7 PF00177.16 KRH94081.1 - 2.9e-34 117.7 0.1 3.5e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3113 PF11310.3 KRH94082.1 - 1.3 8.7 23.3 25 4.6 0.2 6.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3113) POC1 PF10450.4 KRH94083.1 - 0.0038 16.0 0.1 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 POC1 chaperone Helicase_RecD PF05127.9 KRH94084.1 - 2.8e-29 102.0 2.3 9.5e-23 80.7 0.0 2.8 1 1 1 2 2 2 2 Helicase DUF1726 PF08351.6 KRH94084.1 - 8.1e-11 41.4 0.5 4.4e-10 39.1 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1726) DUF3086 PF11285.3 KRH94085.1 - 0.032 13.0 1.3 0.055 12.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF3560 PF12083.3 KRH94087.1 - 0.12 12.4 0.3 0.19 11.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3560) CBFD_NFYB_HMF PF00808.18 KRH94088.1 - 0.061 13.3 0.1 0.08 13.0 0.1 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ras PF00071.17 KRH94089.1 - 4.1e-51 172.5 0.0 4.9e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH94089.1 - 8.5e-11 42.3 0.0 2e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KRH94089.1 - 5.6e-08 32.2 0.0 8.1e-08 31.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KRH94089.1 - 9.2e-05 21.6 0.0 0.00012 21.3 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ribosomal_L30_N PF08079.7 KRH94089.1 - 0.0004 20.3 0.4 0.00079 19.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain GTP_EFTU PF00009.22 KRH94089.1 - 0.023 14.1 0.1 0.22 10.9 0.1 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KRH94089.1 - 0.048 13.1 0.0 1.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1327 PF07041.6 KRH94089.1 - 0.063 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) MMR_HSR1 PF01926.18 KRH94089.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pyrophosphatase PF00719.14 KRH94090.1 - 5.7e-43 146.0 0.8 8.8e-43 145.4 0.6 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase RNA_pol_Rpb6 PF01192.17 KRH94091.1 - 1e-11 44.4 0.2 1.6e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF3445 PF11927.3 KRH94092.1 - 0.0057 16.0 0.5 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) Tat PF00539.13 KRH94092.1 - 1.7 8.2 9.2 4.1 7.0 6.4 1.6 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) RCC1 PF00415.13 KRH94093.1 - 1.5e-26 92.3 0.1 5.7e-06 26.4 0.0 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KRH94093.1 - 1.6e-18 65.7 5.2 2.2e-06 27.1 0.0 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat KOW PF00467.24 KRH94094.1 - 6.7e-05 22.4 1.6 8.6e-05 22.1 0.3 1.7 2 0 0 2 2 2 1 KOW motif ECR1_N PF14382.1 KRH94097.1 - 5.8e-05 22.3 0.0 9.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RNA_pol_A_CTD PF03118.10 KRH94097.1 - 0.019 14.3 0.4 1.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain SPC25 PF06703.6 KRH94100.1 - 4.2e-22 78.4 2.1 4.2e-22 78.4 1.4 1.5 2 0 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BCLP PF12304.3 KRH94100.1 - 0.037 13.4 0.4 0.057 12.8 0.3 1.2 1 0 0 1 1 1 0 Beta-casein like protein Hexapep PF00132.19 KRH94101.1 - 1.5e-07 30.6 0.1 0.0041 16.5 0.0 3.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DDE_3 PF13358.1 KRH94103.1 - 2e-08 34.1 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.12 KRH94107.1 - 0.016 15.2 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein BicD PF09730.4 KRH94108.1 - 0.046 12.0 0.0 0.046 12.0 0.0 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D RVT_1 PF00078.22 KRH94109.1 - 2.3e-09 36.9 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH94110.1 - 0.016 15.3 0.1 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain Stap_Strp_toxin PF01123.15 KRH94110.1 - 0.14 12.6 0.1 0.23 11.9 0.1 1.5 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain Retrotrans_gag PF03732.12 KRH94111.1 - 0.059 13.4 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein ARGLU PF15346.1 KRH94111.1 - 0.11 12.3 0.6 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF1447 PF07288.6 KRH94111.1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) PocR PF10114.4 KRH94114.1 - 0.048 12.8 0.3 0.049 12.7 0.2 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR UPF0182 PF03699.8 KRH94114.1 - 0.081 10.8 0.1 0.09 10.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) RVP PF00077.15 KRH94115.1 - 6.2e-09 35.6 0.2 1.3e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH94115.1 - 1.7e-07 31.6 0.1 3.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 KRH94115.1 - 2.5e-06 26.9 0.1 6.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 KRH94115.1 - 0.00024 21.0 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH94115.1 - 0.00031 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2E PF12382.3 KRH94115.1 - 0.016 15.0 0.1 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon peptidase Asp_protease PF09668.5 KRH94115.1 - 0.017 14.6 0.1 0.062 12.8 0.0 2.0 2 1 0 2 2 2 0 Aspartyl protease Peptidase_A3 PF02160.10 KRH94115.1 - 0.044 13.3 0.2 0.089 12.3 0.1 1.5 1 1 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Methyltransf_12 PF08242.7 KRH94115.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RVT_thumb PF06817.9 KRH94116.1 - 0.025 14.1 0.0 0.057 13.0 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase thumb domain rve PF00665.21 KRH94117.1 - 8.1e-20 71.1 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Proteasome PF00227.21 KRH94118.1 - 6.7e-48 162.4 0.4 8.8e-48 162.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2964 PF11177.3 KRH94121.1 - 0.29 11.0 14.2 0.25 11.3 2.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2964) PepSY_TM PF03929.11 KRH94121.1 - 6.9 7.2 19.0 5.7 7.5 0.0 5.1 5 0 0 5 5 5 0 PepSY-associated TM helix DUF4234 PF14018.1 KRH94121.1 - 8.6 6.1 41.9 1 9.1 4.1 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4234) Got1 PF04178.7 KRH94122.1 - 2.5e-21 75.9 20.1 3.8e-21 75.3 13.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2085 PF09858.4 KRH94122.1 - 0.24 11.5 6.3 4.5 7.4 0.6 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) CBFD_NFYB_HMF PF00808.18 KRH94123.1 - 6.6e-19 67.7 0.9 9.2e-19 67.2 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KRH94123.1 - 1.1e-10 41.4 0.3 1.5e-10 41.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KRH94123.1 - 0.073 12.8 0.3 0.098 12.4 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PI3_PI4_kinase PF00454.22 KRH94124.1 - 4.6e-21 75.3 0.2 1.6e-19 70.3 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UDPGP PF01704.13 KRH94126.1 - 1e-146 488.7 2.4 1.3e-146 488.4 1.6 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ATP-synt_F PF01990.12 KRH94127.1 - 2.1e-17 63.2 0.3 2.4e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit TetR_C_4 PF08359.6 KRH94127.1 - 0.098 12.5 0.1 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region Ribosomal_S9 PF00380.14 KRH94128.1 - 6.5e-24 84.4 0.3 7.4e-24 84.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 KRH94129.1 - 2.2e-39 134.8 6.6 3.1e-39 134.3 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Parvo_coat PF00740.13 KRH94129.1 - 0.027 13.4 1.4 0.027 13.4 1.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Ribosomal_L24e PF01246.15 KRH94130.1 - 1.9e-24 85.3 2.9 1.9e-24 85.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DnaB PF00772.16 KRH94130.1 - 0.0005 19.9 0.6 0.00068 19.4 0.4 1.3 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain GHBP PF12772.2 KRH94130.1 - 0.008 15.6 0.2 0.0093 15.4 0.1 1.1 1 0 0 1 1 1 1 Growth hormone receptor binding PIP5K PF01504.13 KRH94131.1 - 5.9e-52 176.2 13.2 5.9e-52 176.2 9.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PCI PF01399.22 KRH94132.1 - 0.021 15.1 4.8 0.021 15.1 0.7 2.9 2 1 0 2 2 2 0 PCI domain Metalloenzyme PF01676.13 KRH94133.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily Topo_Zn_Ribbon PF08272.6 KRH94133.1 - 0.17 11.2 0.9 0.26 10.6 0.1 1.6 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Septin PF00735.13 KRH94134.1 - 1.5e-53 181.6 12.5 3.7e-44 150.8 5.9 3.0 1 1 1 2 2 2 2 Septin Miro PF08477.8 KRH94134.1 - 1.5e-05 25.4 1.1 0.011 16.1 0.2 3.2 1 1 1 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KRH94134.1 - 0.00015 21.3 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 KRH94134.1 - 0.00073 19.4 0.3 0.00073 19.4 0.2 2.5 2 1 1 3 3 3 1 AAA domain AAA PF00004.24 KRH94134.1 - 0.0065 16.6 0.3 0.017 15.3 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KRH94134.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KRH94134.1 - 0.033 13.6 0.5 0.041 13.3 0.4 1.5 1 1 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KRH94134.1 - 0.035 14.2 0.0 0.088 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KRH94134.1 - 0.037 14.1 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KRH94134.1 - 0.062 13.5 1.3 0.18 12.1 0.8 1.9 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KRH94134.1 - 0.074 12.6 0.7 0.53 9.8 0.2 2.3 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KRH94134.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KRH94134.1 - 0.087 12.6 0.5 0.18 11.6 0.3 1.7 1 1 0 1 1 1 0 Dynamin family NACHT PF05729.7 KRH94134.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cpn60_TCP1 PF00118.19 KRH94135.1 - 4.3e-126 421.3 5.0 5e-126 421.1 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Zip PF02535.17 KRH94136.1 - 6.9e-25 87.7 20.4 2e-22 79.6 3.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Ribonuclease_3 PF00636.21 KRH94138.1 - 6.7e-29 100.6 1.7 5.9e-15 55.7 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KRH94138.1 - 4e-23 81.7 0.8 2.2e-10 40.5 0.0 4.1 3 1 0 3 3 3 2 Ribonuclease-III-like Proteasome PF00227.21 KRH94139.1 - 4.6e-29 101.0 0.0 5.5e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ETRAMP PF09716.5 KRH94140.1 - 0.00035 20.4 0.3 0.001 18.9 0.2 1.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) ApoC-I PF04691.7 KRH94140.1 - 0.0014 18.2 6.0 0.0015 18.1 0.8 2.4 1 1 1 2 2 2 1 Apolipoprotein C-I (ApoC-1) DUF883 PF05957.8 KRH94140.1 - 0.2 12.0 0.6 1.9 8.9 0.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mt_ATP-synt_B PF05405.9 KRH94140.1 - 0.49 9.8 3.8 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_B PF00430.13 KRH94140.1 - 0.59 9.9 8.2 0.023 14.4 1.6 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.2 KRH94140.1 - 1.6 9.1 6.5 15 6.0 4.5 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF1456 PF07308.8 KRH94141.1 - 0.019 14.9 2.4 0.092 12.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) ETRAMP PF09716.5 KRH94141.1 - 0.13 12.2 2.6 0.28 11.1 1.8 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DnaJ PF00226.26 KRH94142.1 - 3.8e-06 26.5 0.9 3.8e-06 26.5 0.6 2.1 3 0 0 3 3 3 1 DnaJ domain PhdYeFM_antitox PF02604.14 KRH94142.1 - 0.0043 16.6 0.4 0.2 11.2 0.1 2.5 1 1 1 2 2 2 1 Antitoxin Phd_YefM, type II toxin-antitoxin system Mis14 PF08641.7 KRH94142.1 - 0.014 15.4 0.2 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Myb_DNA-bind_4 PF13837.1 KRH94142.1 - 0.071 13.2 3.8 0.073 13.2 0.2 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain MscS_porin PF12795.2 KRH94142.1 - 0.08 12.2 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RNA_pol_Rpb5_C PF01191.14 KRH94143.1 - 8.3e-26 89.3 0.5 1.9e-25 88.2 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KRH94143.1 - 3.7e-16 59.3 1.4 8.1e-16 58.2 1.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF2348 PF09807.4 KRH94143.1 - 0.091 11.8 0.2 0.48 9.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2348) CaKB PF03185.10 KRH94143.1 - 0.093 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Rav1p_C PF12234.3 KRH94145.1 - 0.025 12.7 0.6 0.028 12.5 0.5 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal Ribosomal_S13 PF00416.17 KRH94146.1 - 2.8e-21 75.9 1.2 3.4e-21 75.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 SBDS PF01172.13 KRH94147.1 - 4.8e-07 29.4 0.9 2.3e-06 27.2 0.1 2.3 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DZR PF12773.2 KRH94149.1 - 4.2e-05 23.2 16.9 7.8e-05 22.4 4.1 2.5 2 0 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KRH94149.1 - 0.00039 19.5 3.2 0.00039 19.5 2.2 3.6 2 2 1 3 3 3 1 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KRH94149.1 - 0.00095 18.9 8.7 0.0051 16.5 1.1 2.6 2 1 0 2 2 2 2 zinc-ribbons Prok-RING_4 PF14447.1 KRH94149.1 - 0.0016 17.9 0.0 0.0016 17.9 0.0 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 UPF0547 PF10571.4 KRH94149.1 - 0.012 15.3 0.4 0.012 15.3 0.3 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.6 KRH94149.1 - 0.04 13.4 0.2 0.04 13.4 0.2 4.0 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Rad50_zn_hook PF04423.9 KRH94149.1 - 0.045 13.2 1.4 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.4 KRH94149.1 - 0.3 10.4 9.2 1.2 8.6 1.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-TFIIB PF13453.1 KRH94149.1 - 1.1 8.4 13.1 50 3.2 6.6 3.9 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-C3HC4_3 PF13920.1 KRH94149.1 - 1.1 8.9 19.6 1.3 8.7 2.5 3.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NinF PF05810.7 KRH94149.1 - 1.7 8.5 8.4 6 6.7 0.2 3.0 2 1 1 3 3 3 0 NinF protein zinc_ribbon_2 PF13240.1 KRH94149.1 - 2.4 7.7 21.1 0.21 11.1 4.7 3.6 2 2 2 4 4 4 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 KRH94149.1 - 5 6.9 10.7 4.4 7.1 0.2 3.1 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Di19 PF05605.7 KRH94149.1 - 5 7.3 15.5 1.1 9.4 1.7 3.7 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C4pol PF14260.1 KRH94149.1 - 6.2 6.8 10.2 3.1 7.8 1.5 2.8 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 KRH94151.1 - 7.4e-06 25.6 3.9 7.4e-06 25.6 2.7 2.5 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KRH94151.1 - 0.00039 19.5 0.9 0.00039 19.5 0.6 2.8 3 0 0 3 3 3 1 zinc-ribbon domain UPF0547 PF10571.4 KRH94151.1 - 0.011 15.4 1.4 0.011 15.4 0.9 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.6 KRH94151.1 - 0.026 14.0 0.0 0.026 14.0 0.0 3.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 KRH94151.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.5 3 1 0 3 3 3 0 Nudix N-terminal DUF4182 PF13790.1 KRH94151.1 - 3.7 7.4 11.0 9.8 6.0 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) Cytochrom_CIII PF02085.11 KRH94151.1 - 5.1 7.2 7.7 73 3.5 0.4 2.6 1 1 1 2 2 2 0 Class III cytochrome C family Retrotrans_gag PF03732.12 KRH94153.1 - 0.013 15.5 0.5 0.86 9.7 0.1 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein DUF793 PF05633.6 KRH94153.1 - 0.12 11.0 2.0 0.43 9.2 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF793) rve PF00665.21 KRH94154.1 - 9e-19 67.7 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH94154.1 - 0.0098 15.3 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain SLS PF14611.1 KRH94154.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator PTPS PF01242.14 KRH94154.1 - 0.044 13.4 0.1 0.53 9.9 0.0 2.2 1 1 1 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Aminotran_5 PF00266.14 KRH94155.1 - 1.9e-87 293.4 0.0 2.2e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KRH94155.1 - 4.2e-07 29.3 0.0 5.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KRH94155.1 - 2.6e-06 26.1 0.1 6.3e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 KRH94155.1 - 0.00021 20.4 0.1 0.00031 19.8 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Nop14 PF04147.7 KRH94156.1 - 4.2 5.1 36.7 7.2 4.3 25.4 1.4 1 0 0 1 1 1 0 Nop14-like family DUF3449 PF11931.3 KRH94157.1 - 5.7e-10 39.0 3.4 5.7e-10 39.0 2.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.2 KRH94157.1 - 0.23 11.5 19.1 0.077 13.1 1.6 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KRH94157.1 - 1.7 8.9 17.4 1.9 8.7 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RVT_1 PF00078.22 KRH94160.1 - 0.0024 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLAC1 PF03595.12 KRH94162.1 - 0.038 12.6 2.7 0.04 12.5 1.9 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel Bac_rhodopsin PF01036.13 KRH94162.1 - 0.067 12.4 1.8 0.068 12.4 1.3 1.0 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein Ion_trans PF00520.26 KRH94162.1 - 0.6 9.3 6.4 0.69 9.1 4.4 1.0 1 0 0 1 1 1 0 Ion transport protein PKD_channel PF08016.7 KRH94162.1 - 0.74 8.1 5.0 0.74 8.1 3.5 1.0 1 0 0 1 1 1 0 Polycystin cation channel GP41 PF00517.12 KRH94162.1 - 1 8.8 4.3 1.1 8.7 3.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF818 PF05677.7 KRH94162.1 - 6.8 5.3 6.8 6.7 5.3 4.7 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) zf-DHHC PF01529.15 KRH94162.1 - 6.8 6.0 5.9 7.1 5.9 4.1 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Gln-synt_N PF03951.14 KRH94163.1 - 0.079 12.5 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain zf-RING_UBOX PF13445.1 KRH94163.1 - 0.26 11.0 4.4 0.34 10.6 1.1 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Macoilin PF09726.4 KRH94163.1 - 1 7.5 12.6 1.1 7.4 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 KRH94163.1 - 1.2 7.1 22.9 1.6 6.7 15.9 1.0 1 0 0 1 1 1 0 Utp14 protein Mitofilin PF09731.4 KRH94163.1 - 1.4 7.4 12.1 1.7 7.2 8.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Menin PF05053.8 KRH94163.1 - 1.8 6.6 11.2 2.2 6.3 7.7 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 KRH94163.1 - 2.7 7.2 26.0 3.5 6.9 18.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF4551 PF15087.1 KRH94163.1 - 3.1 6.0 11.3 3.7 5.7 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 KRH94163.1 - 4.3 4.9 17.6 4.8 4.7 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.10 KRH94163.1 - 4.5 6.4 11.9 6 6.0 8.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NUMOD1 PF07453.8 KRH94166.1 - 0.1 12.4 0.4 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 NUMOD1 domain Ricin_B_lectin PF00652.17 KRH94169.1 - 0.0048 16.9 0.4 0.0086 16.1 0.3 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ribosomal_L21e PF01157.13 KRH94170.1 - 1.5e-29 101.7 3.7 2.2e-29 101.1 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e PVL_ORF50 PF07768.6 KRH94170.1 - 0.0068 16.3 2.0 0.0068 16.3 1.4 1.7 2 0 0 2 2 2 1 PVL ORF-50-like family S4 PF01479.20 KRH94172.1 - 2e-09 36.7 0.3 3.8e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KRH94172.1 - 0.00011 22.5 0.5 0.0002 21.6 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF826 PF05696.6 KRH94172.1 - 0.017 15.2 0.4 0.028 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Reo_sigmaC PF04582.7 KRH94173.1 - 0.033 13.3 9.1 0.0088 15.2 3.3 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tup_N PF08581.5 KRH94173.1 - 0.56 10.4 8.7 0.16 12.1 0.5 2.9 2 1 1 3 3 3 0 Tup N-terminal MSC PF09402.5 KRH94175.1 - 0.0027 16.4 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Fungal_trans PF04082.13 KRH94175.1 - 0.011 14.5 0.9 0.014 14.2 0.6 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF912 PF06024.7 KRH94175.1 - 0.093 12.7 0.1 0.093 12.7 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1117 PF06547.7 KRH94175.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) CBFB_NFYA PF02045.10 KRH94176.1 - 3.2e-18 65.9 1.1 8.8e-18 64.5 0.7 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B WD40 PF00400.27 KRH94177.1 - 2.2e-21 74.8 1.7 1e-05 25.1 0.0 6.9 5 1 2 8 8 8 3 WD domain, G-beta repeat MbeD_MobD PF04899.7 KRH94178.1 - 7.2e-05 22.6 0.1 0.31 10.9 0.1 2.6 1 1 1 2 2 2 2 MbeD/MobD like IncA PF04156.9 KRH94178.1 - 0.00068 19.2 5.8 0.00091 18.8 4.0 1.2 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 KRH94178.1 - 0.0013 18.5 24.5 0.029 14.1 9.9 2.1 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 KRH94178.1 - 0.0014 17.9 2.6 0.0018 17.6 1.8 1.2 1 0 0 1 1 1 1 Laminin Domain I Nup54 PF13874.1 KRH94178.1 - 0.0053 16.4 6.1 0.051 13.2 1.9 1.9 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 ATG16 PF08614.6 KRH94178.1 - 0.0054 16.5 9.4 0.011 15.6 6.0 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.7 KRH94178.1 - 0.014 15.7 4.2 0.089 13.1 2.9 2.0 1 1 0 1 1 1 0 SlyX DUF1664 PF07889.7 KRH94178.1 - 0.016 15.0 6.0 0.019 14.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.3 KRH94178.1 - 0.016 15.0 5.2 0.02 14.8 3.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 KRH94178.1 - 0.019 14.6 8.0 0.023 14.4 5.5 1.1 1 0 0 1 1 1 0 Laminin Domain II COG5 PF10392.4 KRH94178.1 - 0.021 14.7 7.4 0.027 14.4 5.1 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Spc7 PF08317.6 KRH94178.1 - 0.022 13.4 7.4 0.027 13.1 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KRH94178.1 - 0.053 12.4 5.6 0.082 11.8 3.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KRH94178.1 - 0.053 13.0 12.9 0.23 10.9 2.1 2.1 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 KRH94178.1 - 0.066 11.0 2.4 0.069 11.0 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4631 PF15450.1 KRH94178.1 - 0.074 11.3 8.0 0.45 8.7 5.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4631) PDZ_2 PF13180.1 KRH94178.1 - 0.099 12.5 3.8 3.9 7.4 0.3 2.2 1 1 1 2 2 2 0 PDZ domain DUF724 PF05266.9 KRH94178.1 - 0.1 12.2 7.5 0.13 11.8 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.5 KRH94178.1 - 0.12 12.5 13.5 0.71 9.9 4.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OEP PF02321.13 KRH94178.1 - 0.12 11.9 5.6 2.5 7.6 0.3 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein CENP-H PF05837.7 KRH94178.1 - 0.12 12.5 11.0 0.6 10.3 3.1 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Vps51 PF08700.6 KRH94178.1 - 0.17 11.7 8.8 1.6 8.6 1.2 2.2 1 1 1 2 2 2 0 Vps51/Vps67 CorA PF01544.13 KRH94178.1 - 0.17 10.9 4.7 0.21 10.6 3.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AcylCoA_dehyd_C PF12186.3 KRH94178.1 - 0.18 11.6 2.9 6.4 6.6 0.1 2.4 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF2935 PF11155.3 KRH94178.1 - 0.19 11.8 7.3 0.36 10.9 5.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) GP41 PF00517.12 KRH94178.1 - 0.26 10.8 4.4 3.2 7.2 3.1 2.0 1 1 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.11 KRH94178.1 - 0.27 9.2 2.5 0.34 8.9 1.7 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2185 PF09951.4 KRH94178.1 - 0.32 10.8 3.2 15 5.4 0.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2185) Prefoldin PF02996.12 KRH94178.1 - 0.36 10.4 13.3 0.6 9.7 2.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Uds1 PF15456.1 KRH94178.1 - 0.36 10.8 5.4 0.78 9.7 3.7 1.5 1 1 0 1 1 1 0 Up-regulated During Septation PMC2NT PF08066.7 KRH94178.1 - 0.39 11.0 4.2 37 4.7 2.9 2.6 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF4200 PF13863.1 KRH94178.1 - 0.39 10.6 12.8 1.3 9.0 8.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Nsp1_C PF05064.8 KRH94178.1 - 0.4 10.3 5.5 1.2 8.8 3.5 1.7 1 1 0 1 1 1 0 Nsp1-like C-terminal region CHD5 PF04420.9 KRH94178.1 - 0.46 10.1 5.6 0.6 9.7 3.9 1.3 1 0 0 1 1 1 0 CHD5-like protein Snapin_Pallidin PF14712.1 KRH94178.1 - 0.47 10.7 13.1 1 9.6 9.1 1.6 1 1 0 1 1 1 0 Snapin/Pallidin PT-HINT PF07591.6 KRH94178.1 - 0.49 10.2 2.3 12 5.8 0.2 2.0 1 1 1 2 2 2 0 Pretoxin HINT domain AATF-Che1 PF13339.1 KRH94178.1 - 0.49 10.5 7.2 4.2 7.5 5.0 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF342 PF03961.8 KRH94178.1 - 0.51 8.6 10.0 0.58 8.5 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ACCA PF03255.9 KRH94178.1 - 0.55 9.7 9.7 1.1 8.7 3.2 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FAE1_CUT1_RppA PF08392.7 KRH94178.1 - 0.6 9.1 3.7 0.61 9.1 0.9 1.9 1 1 1 2 2 2 0 FAE1/Type III polyketide synthase-like protein GrpE PF01025.14 KRH94178.1 - 0.84 9.1 4.3 2.7 7.5 3.1 1.7 1 1 0 1 1 1 0 GrpE LPP PF04728.8 KRH94178.1 - 0.96 9.2 4.9 35 4.3 0.0 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF3962 PF13111.1 KRH94178.1 - 1 8.7 9.5 0.54 9.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3962) NPV_P10 PF05531.7 KRH94178.1 - 1.2 9.4 5.8 3.3 8.0 4.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 KRH94178.1 - 1.4 9.3 7.4 3.3 8.0 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Med4 PF10018.4 KRH94178.1 - 2 7.7 11.1 23 4.3 2.3 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3251 PF11622.3 KRH94178.1 - 2.3 7.6 4.2 8.8 5.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3251) HCMV_UL139 PF12507.3 KRH94178.1 - 2.6 8.2 6.1 85 3.3 4.2 2.2 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein BLOC1_2 PF10046.4 KRH94178.1 - 2.8 8.1 13.8 4.7 7.4 9.5 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoU PF01895.14 KRH94178.1 - 4.1 7.9 8.4 27 5.3 5.8 2.0 1 1 0 1 1 1 0 PhoU domain DDE_Tnp_IS1 PF03400.8 KRH94178.1 - 5 7.2 6.2 12 6.0 0.4 2.1 1 1 1 2 2 2 0 IS1 transposase AKNA PF12443.3 KRH94178.1 - 7.1 6.6 7.6 23 5.0 1.6 2.3 1 1 2 3 3 3 0 AT-hook-containing transcription factor RecR PF02132.10 KRH94178.1 - 7.4 6.1 6.5 87 2.6 0.0 3.6 2 2 2 5 5 5 0 RecR protein O-antigen_lig PF13425.1 KRH94182.1 - 0.04 13.8 0.2 0.048 13.6 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CoxIIa PF08113.6 KRH94182.1 - 0.89 9.3 5.1 1.4 8.6 3.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Abhydrolase_6 PF12697.2 KRH94186.1 - 2.1e-06 27.8 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KRH94186.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KRH94186.1 - 0.0083 15.7 1.5 0.21 11.1 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KRH94186.1 - 0.053 13.1 0.0 0.23 11.0 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_6 PF12697.2 KRH94187.1 - 5.9e-05 23.0 0.0 8.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Frigida PF07899.6 KRH94188.1 - 0.015 14.0 0.1 0.017 13.9 0.1 1.0 1 0 0 1 1 1 0 Frigida-like protein HSP70 PF00012.15 KRH94189.1 - 2.9e-163 544.0 9.1 7e-90 301.6 0.1 2.7 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KRH94189.1 - 1.3e-08 33.8 0.1 0.0021 16.6 0.0 3.5 3 0 0 3 3 3 3 MreB/Mbl protein FtsA PF14450.1 KRH94189.1 - 1.5e-05 24.8 0.6 0.42 10.4 0.0 4.2 3 2 0 3 3 3 2 Cell division protein FtsA StbA PF06406.6 KRH94189.1 - 0.00088 18.3 0.3 0.032 13.1 0.0 3.1 3 0 0 3 3 3 1 StbA protein FGGY_C PF02782.11 KRH94189.1 - 0.0041 16.7 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KRH94189.1 - 0.011 14.8 0.1 0.15 11.0 0.0 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Syntaxin-6_N PF09177.6 KRH94189.1 - 2.7 8.4 7.8 1.2 9.6 1.5 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spore_III_AF PF09581.5 KRH94190.1 - 0.0046 16.8 0.7 0.005 16.7 0.5 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) DUF3387 PF11867.3 KRH94190.1 - 0.041 12.8 0.7 0.051 12.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) zf-HC2 PF13490.1 KRH94191.1 - 0.01 15.7 0.1 0.042 13.8 0.0 1.9 2 0 0 2 2 2 0 Putative zinc-finger YopD PF05844.7 KRH94191.1 - 0.11 11.4 0.6 0.16 10.9 0.4 1.1 1 0 0 1 1 1 0 YopD protein U-box PF04564.10 KRH94191.1 - 0.12 12.3 0.1 3.6 7.5 0.0 2.8 2 1 0 2 2 2 0 U-box domain Toxin_20 PF08089.6 KRH94191.1 - 0.28 11.1 2.6 0.57 10.1 1.8 1.5 1 0 0 1 1 1 0 Huwentoxin-II family Rer1 PF03248.8 KRH94192.1 - 7.2e-53 178.7 8.9 8e-53 178.6 6.1 1.0 1 0 0 1 1 1 1 Rer1 family DUF2207 PF09972.4 KRH94192.1 - 0.31 9.5 3.0 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RNA_pol_Rpb4 PF03874.11 KRH94193.1 - 5.5e-17 61.8 1.1 6.2e-17 61.6 0.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 HRDC PF00570.18 KRH94193.1 - 0.023 14.4 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 HRDC domain DUF2893 PF11459.3 KRH94193.1 - 0.11 12.3 0.1 17 5.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknwon function (DUF2893) LUC7 PF03194.10 KRH94194.1 - 0.00011 21.7 12.8 0.00064 19.3 8.7 2.0 1 1 0 1 1 1 1 LUC7 N_terminus NAD_binding_6 PF08030.7 KRH94194.1 - 0.51 10.2 6.3 0.69 9.8 2.3 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Peptidase_C13 PF01650.13 KRH94195.1 - 7.2e-21 74.6 0.1 8.6e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 KRH94195.1 - 0.00068 19.3 0.1 0.00089 19.0 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C25 PF01364.13 KRH94195.1 - 0.035 13.0 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 DUF4131 PF13567.1 KRH94196.1 - 0.12 11.7 17.3 0.21 10.9 1.9 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) Sex_peptide PF08138.6 KRH94196.1 - 0.98 9.3 4.1 4.2 7.3 0.2 3.0 3 0 0 3 3 3 0 Sex peptide (SP) family EamA PF00892.15 KRH94196.1 - 1 9.4 34.5 0.13 12.3 11.4 3.4 2 2 1 3 3 3 0 EamA-like transporter family Pkinase PF00069.20 KRH94197.1 - 8.3e-46 156.2 2.0 1.1e-43 149.2 1.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH94197.1 - 1.7e-24 86.3 0.1 1.6e-21 76.5 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KRH94197.1 - 2.1e-05 24.3 0.0 0.0048 16.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 KRH94197.1 - 3.7e-05 23.0 0.4 3.7e-05 23.0 0.3 2.6 3 0 0 3 3 3 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KRH94197.1 - 6.7e-05 22.3 0.2 6.7e-05 22.3 0.2 2.5 2 1 0 3 3 3 1 RIO1 family Kinase-like PF14531.1 KRH94197.1 - 0.00025 20.1 0.0 0.009 15.0 0.0 2.8 2 1 1 3 3 3 1 Kinase-like DUF2318 PF10080.4 KRH94197.1 - 0.026 14.3 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) NOT2_3_5 PF04153.13 KRH94198.1 - 6.3e-11 42.2 2.5 8e-11 41.9 1.4 1.3 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RrnaAD PF00398.15 KRH94199.1 - 9.3e-53 178.9 0.2 1.1e-52 178.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KRH94199.1 - 9.2e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KRH94199.1 - 1.2e-06 29.0 0.0 1.9e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KRH94199.1 - 1.8e-06 27.6 0.1 3e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KRH94199.1 - 7.9e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KRH94199.1 - 2.5e-05 24.5 0.0 0.00011 22.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KRH94199.1 - 3.3e-05 23.3 0.0 5.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KRH94199.1 - 0.00049 20.5 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KRH94199.1 - 0.0089 15.3 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 KRH94199.1 - 0.016 15.6 0.0 0.068 13.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 KRH94199.1 - 0.016 14.5 0.1 0.098 12.0 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KRH94199.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KRH94199.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KRH94199.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KRH94199.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1133 PF06576.6 KRH94199.1 - 0.14 11.3 1.0 8 5.6 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1133) Uteroglobin PF01099.12 KRH94199.1 - 0.18 11.6 1.7 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Uteroglobin family Mer2 PF09074.5 KRH94202.1 - 0.18 11.7 8.2 0.26 11.1 5.7 1.2 1 0 0 1 1 1 0 Mer2 rve PF00665.21 KRH94203.1 - 6.7e-14 52.0 0.1 9.3e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KRH94203.1 - 0.00054 19.4 0.1 0.001 18.5 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain LIF_OSM PF01291.12 KRH94207.1 - 0.094 12.6 1.9 2.2 8.1 0.1 2.1 1 1 1 2 2 2 0 LIF / OSM family rve_3 PF13683.1 KRH94209.1 - 0.0039 16.6 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Pox_I1 PF03289.8 KRH94209.1 - 0.066 12.0 0.1 0.067 12.0 0.1 1.0 1 0 0 1 1 1 0 Poxvirus protein I1 SNF2_N PF00176.18 KRH94210.1 - 2.7e-13 49.3 0.0 2.7e-13 49.3 0.0 3.2 2 2 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.3 KRH94210.1 - 0.069 12.8 11.1 4.7 6.9 0.4 4.8 2 1 3 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like Patatin PF01734.17 KRH94210.1 - 3.7 7.4 5.1 14 5.5 3.2 2.1 1 1 0 1 1 1 0 Patatin-like phospholipase UCH PF00443.24 KRH94211.1 - 5.4e-08 32.2 10.6 5.4e-08 32.2 7.3 2.9 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ipi1_N PF12333.3 KRH94211.1 - 0.047 13.6 0.0 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Tsg PF04668.7 KRH94212.1 - 3.9 7.6 7.2 1.3 9.2 0.1 2.5 2 1 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Hydrolase PF00702.21 KRH94213.1 - 3.1e-12 47.3 0.0 4.1e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KRH94213.1 - 4.8e-07 30.1 0.0 7.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SHMT PF00464.14 KRH94213.1 - 0.1 10.9 0.1 1.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Serine hydroxymethyltransferase DS PF01916.12 KRH94215.1 - 2.5e-42 145.0 0.4 1.1e-36 126.5 0.2 2.1 1 1 1 2 2 2 2 Deoxyhypusine synthase UPF0113 PF03657.8 KRH94216.1 - 6.7e-12 45.3 2.0 9e-12 44.9 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KRH94216.1 - 7.5e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PUA domain tRNA-synt_1e PF01406.14 KRH94219.1 - 1.8e-86 289.9 5.0 4.6e-58 196.7 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 KRH94219.1 - 4.2e-07 28.3 0.2 0.0011 17.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KRH94219.1 - 6.9e-07 28.2 0.7 0.00067 18.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 KRH94219.1 - 0.00043 19.2 2.1 0.0018 17.1 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (R) DDE_Tnp_1_7 PF13843.1 KRH94221.1 - 1.5e-05 24.2 0.2 1.5e-05 24.2 0.2 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF4498 PF14926.1 KRH94221.1 - 0.069 12.2 0.3 0.072 12.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) RVT_1 PF00078.22 KRH94222.1 - 6.2e-22 78.0 0.1 2e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH94222.1 - 3.6e-05 23.4 0.6 7.6e-05 22.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 KRH94222.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 KRH94223.1 - 6.6e-10 39.1 0.0 6.7e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DUF3104 PF11302.3 KRH94226.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DDE_Tnp_IS1595 PF12762.2 KRH94228.1 - 3.1e-31 108.2 0.5 1.5e-30 106.0 0.2 2.0 2 0 0 2 2 2 1 ISXO2-like transposase domain T4_baseplate PF12322.3 KRH94228.1 - 0.00023 20.5 0.5 0.00054 19.2 0.4 1.7 1 1 0 1 1 1 1 T4 bacteriophage base plate protein DNA_ligase_ZBD PF03119.11 KRH94228.1 - 0.0017 17.9 1.4 0.017 14.8 1.0 2.2 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.14 KRH94228.1 - 0.014 14.8 0.2 0.038 13.4 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger RVT_1 PF00078.22 KRH94229.1 - 3.2e-23 82.2 0.8 8.7e-23 80.7 0.6 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH94229.1 - 1.6e-17 63.6 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 KRH94229.1 - 7.7e-06 26.3 0.1 2.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag_pre-integrs PF13976.1 KRH94229.1 - 0.00044 19.8 0.1 0.0013 18.3 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP_2 PF08284.6 KRH94229.1 - 0.00071 19.5 0.1 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH94229.1 - 0.00084 19.2 0.0 0.0039 17.0 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH94229.1 - 0.0015 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4414 PF14377.1 KRH94229.1 - 0.0076 16.1 1.0 0.018 14.9 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) Asp_protease PF09668.5 KRH94229.1 - 0.0093 15.5 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Pox_A32 PF04665.7 KRH94231.1 - 0.074 12.3 1.1 0.077 12.2 0.8 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein GBP PF02263.14 KRH94231.1 - 0.12 11.3 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain GCS PF03074.11 KRH94232.1 - 2.1e-39 135.6 4.7 4.4e-30 104.9 3.8 2.4 2 1 0 2 2 2 2 Glutamate-cysteine ligase EamA PF00892.15 KRH94233.1 - 0.0063 16.5 11.8 0.0063 16.5 8.2 3.7 2 2 1 3 3 3 1 EamA-like transporter family DUF1792 PF08759.6 KRH94234.1 - 0.019 14.5 0.2 0.019 14.5 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1792) MCM PF00493.18 KRH94235.1 - 1.4e-96 323.1 0.9 2.6e-96 322.3 0.6 1.4 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KRH94235.1 - 4e-06 26.1 0.1 1.4e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KRH94235.1 - 0.0049 16.6 0.1 0.017 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KRH94235.1 - 0.0066 16.6 0.0 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.1 KRH94235.1 - 0.0092 16.4 0.2 1.6 9.2 0.0 3.0 2 1 0 2 2 2 1 MCM N-terminal domain Dynein_light PF01221.13 KRH94236.1 - 8e-09 35.3 0.1 9.9e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 BTG PF07742.7 KRH94236.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 BTG family RINT1_TIP1 PF04437.8 KRH94237.1 - 2.5e-08 32.9 12.4 2.5e-08 32.9 8.6 3.7 2 1 1 3 3 3 3 RINT-1 / TIP-1 family Ferritin PF00210.19 KRH94237.1 - 0.0093 15.7 5.7 0.0093 15.7 3.9 2.7 3 0 0 3 3 3 1 Ferritin-like domain EmrE PF13536.1 KRH94238.1 - 0.00017 21.7 4.8 0.00017 21.7 3.3 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KRH94238.1 - 0.0024 17.9 8.4 0.0024 17.9 5.8 2.8 2 2 0 2 2 2 1 EamA-like transporter family Pox_C7_F8A PF03287.9 KRH94239.1 - 0.042 13.5 0.3 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 Poxvirus C7/F8A protein Alpha-L-AF_C PF06964.7 KRH94245.1 - 0.09 12.5 0.1 1.5 8.6 0.0 2.1 1 1 1 2 2 2 0 Alpha-L-arabinofuranosidase C-terminus zf-U1 PF06220.7 KRH94250.1 - 0.072 12.6 0.5 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 U1 zinc finger mRNA_triPase PF02940.10 KRH94252.1 - 0.036 13.8 1.6 0.045 13.4 1.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain AAA_32 PF13654.1 KRH94252.1 - 0.079 11.6 3.4 0.086 11.4 2.4 1.0 1 0 0 1 1 1 0 AAA domain DUF365 PF04033.7 KRH94252.1 - 0.099 12.6 2.7 0.11 12.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF365) Thioredoxin_7 PF13899.1 KRH94252.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF342 PF03961.8 KRH94252.1 - 0.75 8.1 4.7 1.1 7.5 3.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 KRH94252.1 - 3.1 7.8 8.5 7.1 6.6 1.9 2.4 1 1 1 2 2 2 0 bZIP transcription factor WD40 PF00400.27 KRH94253.1 - 4.6e-29 99.2 6.2 3.6e-07 29.8 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KRH94253.1 - 3.2e-06 26.9 3.7 1.6 8.5 0.0 5.4 5 1 1 6 6 6 3 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.1 KRH94253.1 - 0.029 13.3 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FlaC_arch PF05377.6 KRH94254.1 - 0.044 13.6 0.9 0.12 12.3 0.2 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Med4 PF10018.4 KRH94254.1 - 0.059 12.7 2.2 0.066 12.6 1.5 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 KRH94254.1 - 0.062 13.5 0.5 0.083 13.1 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RP-C_C PF11800.3 KRH94254.1 - 0.069 12.8 0.2 0.069 12.8 0.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Baculo_PEP_C PF04513.7 KRH94254.1 - 0.077 12.8 0.4 0.085 12.6 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pyr_redox_2 PF07992.9 KRH94256.1 - 6.6e-29 101.2 0.6 8.1e-29 100.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KRH94256.1 - 2.3e-14 53.5 2.7 1.8e-12 47.4 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KRH94256.1 - 2.4e-14 53.8 0.3 2.1e-13 50.8 0.0 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KRH94256.1 - 5e-08 32.2 3.9 0.0058 15.5 0.1 4.0 4 0 0 4 4 4 3 Glucose inhibited division protein A HI0933_like PF03486.9 KRH94256.1 - 3.1e-06 25.9 1.1 0.0025 16.3 0.0 3.2 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 KRH94256.1 - 4.8e-06 25.7 1.0 0.00034 19.6 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KRH94256.1 - 0.00021 20.3 0.7 0.18 10.6 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 KRH94256.1 - 0.00045 19.2 3.7 0.00048 19.1 0.0 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KRH94256.1 - 0.0006 18.9 1.0 0.063 12.3 0.1 2.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KRH94256.1 - 0.00095 18.1 1.4 1.1 8.0 0.1 3.8 3 1 1 4 4 4 1 FAD binding domain NAD_binding_7 PF13241.1 KRH94256.1 - 0.0067 16.6 1.4 0.026 14.7 0.0 2.5 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KRH94256.1 - 0.18 11.5 0.1 0.18 11.5 0.0 2.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding DUF2969 PF11184.3 KRH94256.1 - 0.41 10.7 4.6 0.66 10.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) XPA_C PF05181.7 KRH94257.1 - 1.6e-12 46.8 0.0 3.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus DUF2616 PF11077.3 KRH94257.1 - 0.59 9.6 6.3 0.1 12.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) CK_II_beta PF01214.13 KRH94258.1 - 1.1e-46 158.6 0.7 2.1e-46 157.7 0.5 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Ank_4 PF13637.1 KRH94259.1 - 0.1 13.1 0.1 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PBCV_basic_adap PF08789.5 KRH94260.1 - 0.69 9.6 2.5 0.45 10.2 0.1 1.9 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain Lactamase_B_2 PF12706.2 KRH94261.1 - 2.4e-25 89.2 0.2 1.8e-13 50.4 0.0 3.3 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KRH94261.1 - 1e-05 24.9 0.0 0.00036 19.9 0.0 2.8 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KRH94261.1 - 0.0001 22.0 0.1 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Metallophos PF00149.23 KRH94262.1 - 1.4e-30 106.1 0.0 2.3e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Med30 PF11315.3 KRH94262.1 - 0.0046 17.0 2.4 0.011 15.8 1.6 1.6 1 0 0 1 1 1 1 Mediator complex subunit 30 Gag_p12 PF01141.13 KRH94262.1 - 0.013 15.6 0.3 0.33 11.1 0.0 2.6 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Pentapeptide PF00805.17 KRH94263.1 - 0.1 11.8 0.2 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Ribosomal_S25 PF03297.10 KRH94264.1 - 6.1e-17 61.5 6.1 6.1e-17 61.5 4.3 1.3 1 1 0 1 1 1 1 S25 ribosomal protein HTH_45 PF14947.1 KRH94264.1 - 0.0028 17.4 0.2 0.0041 16.8 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix Ribosomal_L23eN PF03939.8 KRH94264.1 - 0.48 10.4 7.6 17 5.5 4.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain Mlp PF03304.8 KRH94265.1 - 0.038 14.0 1.9 0.054 13.4 1.3 1.4 1 1 0 1 1 1 0 Mlp lipoprotein family DUF2683 PF10884.3 KRH94265.1 - 0.12 12.3 0.5 0.23 11.4 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2683) Orthopox_F14 PF06076.7 KRH94265.1 - 0.21 11.6 2.2 0.29 11.2 1.5 1.2 1 0 0 1 1 1 0 Orthopoxvirus F14 protein MutL_C PF08676.6 KRH94266.1 - 5.9e-09 35.6 1.8 1.2e-08 34.7 0.4 2.1 2 1 1 3 3 3 1 MutL C terminal dimerisation domain GLTSCR1 PF15249.1 KRH94267.1 - 1.8e-05 24.7 0.2 5e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region rve PF00665.21 KRH94270.1 - 2.3e-23 82.5 0.1 5e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 KRH94270.1 - 0.00011 21.7 4.0 0.00045 19.8 2.7 2.2 1 1 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 KRH94270.1 - 0.0068 15.9 0.2 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 KRH94270.1 - 0.026 14.4 0.2 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 DDE domain RVT_1 PF00078.22 KRH94271.1 - 4.9e-07 29.3 0.1 8.1e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4367 PF14285.1 KRH94271.1 - 0.019 14.2 0.2 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Glyco_transf_20 PF00982.16 KRH94271.1 - 0.11 10.9 0.1 0.19 10.1 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase family 20 Asp_protease_2 PF13650.1 KRH94272.1 - 1.3e-09 38.4 0.1 2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH94272.1 - 1.9e-08 34.1 0.2 6.7e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 KRH94272.1 - 5.1e-05 23.2 0.1 7.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH94272.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 KRH94272.1 - 0.0019 17.7 0.2 0.018 14.6 0.1 2.1 1 1 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.5 KRH94272.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease zf-C4_Topoisom PF01396.14 KRH94275.1 - 0.011 15.2 1.7 0.019 14.4 1.2 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger PUF PF00806.14 KRH94275.1 - 0.017 14.5 0.4 0.039 13.4 0.2 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat PH PF00169.24 KRH94276.1 - 0.015 15.4 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 PH domain Reo_sigmaC PF04582.7 KRH94277.1 - 0.079 12.1 18.1 0.15 11.1 0.9 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ThiS PF02597.15 KRH94277.1 - 0.98 9.8 4.7 9.1 6.7 0.1 3.4 3 0 0 3 3 3 0 ThiS family Transcrip_act PF04949.8 KRH94278.1 - 0.095 12.3 1.0 0.19 11.3 0.7 1.5 1 0 0 1 1 1 0 Transcriptional activator Pkr1 PF08636.5 KRH94280.1 - 4.6 7.3 6.6 1.6 8.8 2.1 1.9 1 1 1 2 2 2 0 ER protein Pkr1 DUF3953 PF13129.1 KRH94280.1 - 4.6 6.9 7.2 1.4 8.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) GTP_EFTU PF00009.22 KRH94282.1 - 4.8e-34 117.4 0.1 5.5e-34 117.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KRH94282.1 - 1.1e-05 25.9 0.3 0.00016 22.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KRH94282.1 - 1.1e-05 25.3 0.6 3.6e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 KRH94282.1 - 0.011 15.2 0.1 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KRH94282.1 - 0.052 13.3 0.0 11 5.8 0.0 2.9 1 1 1 2 2 2 0 Dynamin family Asp_protease_2 PF13650.1 KRH94283.1 - 4.7e-05 23.8 0.0 8.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94283.1 - 9.6e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH94283.1 - 0.00024 21.0 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH94283.1 - 0.0051 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1409 PF07197.7 KRH94283.1 - 0.035 14.1 0.4 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) GCR PF02155.10 KRH94283.1 - 0.12 11.1 0.2 0.79 8.3 0.0 1.9 2 0 0 2 2 2 0 Glucocorticoid receptor UPF0158 PF03682.8 KRH94284.1 - 0.01 15.4 0.6 0.012 15.2 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF777 PF05606.6 KRH94286.1 - 0.031 13.4 0.5 0.034 13.3 0.4 1.0 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) rve PF00665.21 KRH94287.1 - 1e-22 80.4 0.1 5.8e-22 78.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.1 KRH94287.1 - 0.019 14.7 0.2 4.4 7.1 0.0 3.5 3 1 0 3 3 3 0 Reverse transcriptase-like Peptidase_S7 PF00949.16 KRH94287.1 - 0.053 12.9 0.2 12 5.3 0.0 3.3 3 1 1 4 4 4 0 Peptidase S7, Flavivirus NS3 serine protease RVT_1 PF00078.22 KRH94288.1 - 3.7e-24 85.2 0.2 1.3e-23 83.4 0.2 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 KRH94288.1 - 5.3e-09 35.9 1.6 9.2e-09 35.1 0.1 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH94288.1 - 4.1e-08 33.6 0.1 1e-07 32.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94288.1 - 0.00082 19.1 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH94288.1 - 0.00098 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_thumb PF06817.9 KRH94288.1 - 0.014 14.9 0.0 0.085 12.4 0.0 2.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Asp_protease PF09668.5 KRH94288.1 - 0.015 14.8 0.1 0.038 13.5 0.1 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF4621 PF15414.1 KRH94289.1 - 0.016 13.9 0.1 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) DUF438 PF04282.8 KRH94290.1 - 0.072 12.8 0.0 0.075 12.8 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF438) Transpos_assoc PF13963.1 KRH94291.1 - 0.15 12.0 0.2 0.18 11.8 0.2 1.2 1 0 0 1 1 1 0 Transposase-associated domain Asp_protease_2 PF13650.1 KRH94295.1 - 7.8e-06 26.3 0.1 1.7e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94295.1 - 1.1e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KRH94295.1 - 0.00012 21.8 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.3 KRH94295.1 - 0.0022 17.8 1.3 0.0073 16.2 0.9 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Retrotrans_gag PF03732.12 KRH94295.1 - 0.015 15.3 0.2 6.9 6.8 0.0 2.7 1 1 1 2 2 2 0 Retrotransposon gag protein rve PF00665.21 KRH94295.1 - 0.016 15.3 0.0 0.057 13.5 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain zf-RanBP PF00641.13 KRH94295.1 - 3.2 6.9 5.7 21 4.3 0.1 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others bZIP_1 PF00170.16 KRH94298.1 - 9.1e-08 31.9 2.1 5.5e-07 29.4 1.5 2.4 1 0 0 1 1 1 1 bZIP transcription factor CfAFP PF05264.6 KRH94298.1 - 0.31 10.7 2.7 0.58 9.9 1.9 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) bZIP_2 PF07716.10 KRH94298.1 - 2.6 7.9 13.4 0.04 13.7 2.8 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Ribosomal_L7Ae PF01248.21 KRH94300.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DDE_Tnp_IS1595 PF12762.2 KRH94301.1 - 1.9e-18 66.7 0.5 2.2e-18 66.5 0.4 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain SLT_beta PF02258.11 KRH94303.1 - 0.087 12.6 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Shiga-like toxin beta subunit KIF1B PF12423.3 KRH94304.1 - 0.0017 18.3 1.5 0.0018 18.2 0.2 1.7 2 0 0 2 2 2 1 Kinesin protein 1B Baculo_p24 PF05073.7 KRH94304.1 - 0.0053 16.3 3.9 0.0076 15.8 2.7 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein YTV PF07639.6 KRH94304.1 - 0.039 13.6 1.5 0.039 13.6 1.0 2.1 3 0 0 3 3 3 0 YTV PG_binding_4 PF12229.3 KRH94304.1 - 0.34 11.1 5.4 0.2 11.9 1.8 1.8 1 1 1 2 2 2 0 Putative peptidoglycan binding domain RVT_1 PF00078.22 KRH94305.1 - 9.6e-21 74.1 0.1 1.2e-20 73.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH94305.1 - 0.0081 15.1 0.3 0.011 14.7 0.2 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rep_3 PF01051.16 KRH94305.1 - 0.03 13.9 1.6 0.051 13.1 1.0 1.3 1 1 0 1 1 1 0 Initiator Replication protein POR_N PF01855.14 KRH94307.1 - 0.67 9.4 2.0 1.5 8.2 0.0 2.4 3 0 0 3 3 3 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3175 PF11373.3 KRH94308.1 - 0.094 12.7 1.5 0.32 11.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) RVT_1 PF00078.22 KRH94312.1 - 3.2e-11 43.0 0.0 3.5e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 KRH94312.1 - 0.042 12.7 0.2 0.11 11.4 0.1 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PduV-EutP PF10662.4 KRH94312.1 - 0.091 12.2 0.1 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RPW8 PF05659.6 KRH94312.1 - 0.094 12.2 0.1 0.1 12.1 0.1 1.0 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RVT_1 PF00078.22 KRH94313.1 - 6.8e-17 61.5 0.1 7.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pentapeptide_4 PF13599.1 KRH94315.1 - 0.078 12.7 0.7 0.084 12.6 0.5 1.1 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DNA_pol_E_B PF04042.11 KRH94318.1 - 9.7e-17 60.9 0.2 1.7e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B OGG_N PF07934.7 KRH94319.1 - 1.2e-14 54.2 0.3 3.2e-14 52.9 0.2 1.7 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain DUF4554 PF15091.1 KRH94320.1 - 0.01 14.5 0.7 0.02 13.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) ScpA_ScpB PF02616.9 KRH94320.1 - 0.019 14.5 6.2 0.032 13.8 0.0 2.6 3 0 0 3 3 3 0 ScpA/B protein XPG_N PF00752.12 KRH94320.1 - 0.11 12.7 2.4 2.5 8.4 0.5 2.6 2 0 0 2 2 2 0 XPG N-terminal domain Carb_kinase PF01256.12 KRH94323.1 - 4.2e-31 108.0 0.0 1.6e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase LRR_4 PF12799.2 KRH94324.1 - 6.6e-05 22.4 34.8 0.014 14.9 4.5 6.2 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KRH94324.1 - 0.0009 19.0 18.0 5 7.5 0.0 7.9 9 0 0 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 KRH94324.1 - 0.25 11.6 25.0 34 5.2 0.2 9.4 9 2 1 10 10 10 0 Leucine rich repeat LRR_1 PF00560.28 KRH94324.1 - 0.81 9.9 30.1 11 6.4 0.0 8.9 8 2 0 8 8 8 0 Leucine Rich Repeat DDE_3 PF13358.1 KRH94326.1 - 8.5e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3603 PF12227.3 KRH94326.1 - 0.036 13.1 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) WASH-7_mid PF14744.1 KRH94328.1 - 0.055 12.3 0.2 0.055 12.3 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 rve PF00665.21 KRH94329.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 KRH94330.1 - 4.2e-14 52.6 0.0 1.1e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KRH94330.1 - 0.0012 18.1 2.2 0.0012 18.1 1.5 1.8 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DUF1227 PF06777.6 KRH94330.1 - 0.14 11.9 2.3 2.5 7.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1227) FlbD PF06289.6 KRH94331.1 - 0.49 9.8 3.1 2.6 7.5 0.9 2.4 1 1 1 2 2 2 0 Flagellar protein (FlbD) RVT_1 PF00078.22 KRH94332.1 - 5.6e-09 35.6 0.5 6.6e-08 32.1 0.3 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 KRH94333.1 - 6.3e-06 25.8 2.0 6.3e-06 25.8 1.4 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 KRH94333.1 - 0.036 13.7 0.6 0.09 12.4 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CHC2 PF01807.15 KRH94333.1 - 0.094 12.2 0.2 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 CHC2 zinc finger RVT_1 PF00078.22 KRH94335.1 - 0.041 13.2 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2636 PF11120.3 KRH94336.1 - 0.17 11.4 0.4 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) FA_synthesis PF02504.10 KRH94336.1 - 0.19 10.5 0.5 0.35 9.6 0.0 1.5 2 0 0 2 2 2 0 Fatty acid synthesis protein tRNA-synt_2d PF01409.15 KRH94337.1 - 1.5e-84 283.0 0.0 2.5e-84 282.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KRH94337.1 - 0.0071 15.9 0.1 0.031 13.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) RuvC PF02075.12 KRH94337.1 - 0.067 13.0 0.2 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC ABC_tran PF00005.22 KRH94338.1 - 4.6e-25 88.4 0.0 8.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KRH94338.1 - 7.6e-10 39.2 1.9 7.6e-10 39.2 1.3 3.5 3 2 0 3 3 2 1 AAA domain SMC_N PF02463.14 KRH94338.1 - 2.5e-07 30.1 0.7 5.8e-07 28.9 0.5 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KRH94338.1 - 1.3e-06 28.6 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KRH94338.1 - 0.00016 21.4 0.1 0.00086 19.0 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase SbcCD_C PF13558.1 KRH94338.1 - 0.00019 21.2 0.0 0.0023 17.7 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KRH94338.1 - 0.0005 20.4 3.1 0.0019 18.5 2.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH94338.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 KRH94338.1 - 0.0014 18.4 0.9 0.0021 17.9 0.1 1.7 2 0 0 2 2 1 1 Dynamin family NTPase_1 PF03266.10 KRH94338.1 - 0.0019 17.9 0.3 0.97 9.1 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 KRH94338.1 - 0.0031 16.9 0.1 0.019 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KRH94338.1 - 0.0032 16.6 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KRH94338.1 - 0.0097 15.4 0.3 0.04 13.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KRH94338.1 - 0.011 15.6 0.1 0.25 11.2 0.1 2.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KRH94338.1 - 0.012 16.4 0.1 0.045 14.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 KRH94338.1 - 0.017 14.0 0.2 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KRH94338.1 - 0.027 13.9 1.5 0.054 12.9 0.4 1.9 1 1 1 2 2 2 0 AAA-like domain cobW PF02492.14 KRH94338.1 - 0.029 13.8 0.3 0.046 13.1 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KRH94338.1 - 0.033 13.8 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KRH94338.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 KRH94338.1 - 0.04 13.8 0.4 0.13 12.1 0.3 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KRH94338.1 - 0.049 14.1 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_24 PF13479.1 KRH94338.1 - 0.056 13.0 0.2 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KRH94338.1 - 0.063 13.5 0.1 0.24 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KRH94338.1 - 0.083 12.3 0.0 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KRH94338.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KRH94338.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KRH94338.1 - 0.11 12.2 0.1 1.9 8.2 0.1 2.7 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KRH94338.1 - 0.23 11.6 2.7 2.8 8.1 0.8 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2839 PF10999.3 KRH94338.1 - 0.3 11.1 1.1 4.4 7.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) PARG_cat PF05028.9 KRH94339.1 - 0.01 15.1 0.4 0.012 14.8 0.3 1.2 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) TNFR_c6 PF00020.13 KRH94339.1 - 0.16 12.0 0.7 0.41 10.7 0.2 2.0 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region DivIC PF04977.10 KRH94340.1 - 0.72 9.3 9.1 0.77 9.2 0.0 4.2 4 0 0 4 4 4 0 Septum formation initiator RabGAP-TBC PF00566.13 KRH94345.1 - 1.1e-36 126.3 10.5 1.8e-36 125.6 7.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RICH PF05062.7 KRH94345.1 - 6 7.0 9.2 40 4.4 0.0 3.7 2 1 1 4 4 4 0 RICH domain PTH2 PF01981.11 KRH94348.1 - 3.2e-08 33.2 0.1 7.9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 Peptidase_M24 PF00557.19 KRH94349.1 - 6e-25 88.0 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KRH94349.1 - 1.9e-14 54.2 0.0 1.8e-13 51.0 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain HECT PF00632.20 KRH94350.1 - 2.1e-73 247.2 3.3 2.1e-73 247.2 2.3 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PLDc_2 PF13091.1 KRH94351.1 - 1.4e-08 34.5 0.3 2.6e-08 33.6 0.1 1.5 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.17 KRH94351.1 - 0.0014 18.3 0.3 0.0043 16.7 0.2 1.8 1 0 0 1 1 1 1 Phospholipase D Active site motif DDE_Tnp_IS1595 PF12762.2 KRH94354.1 - 1.8e-10 40.8 0.7 1.9e-10 40.7 0.5 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain Tfb4 PF03850.9 KRH94356.1 - 2.9e-08 33.3 18.4 5.4e-05 22.6 3.2 3.1 2 1 1 3 3 3 3 Transcription factor Tfb4 E1-E2_ATPase PF00122.15 KRH94358.1 - 3.4e-33 114.5 9.6 3.3e-17 62.3 0.3 3.1 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.21 KRH94358.1 - 2e-21 77.4 0.0 6.5e-21 75.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KRH94358.1 - 1.2e-15 58.2 0.0 3.8e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KRH94358.1 - 2.8e-12 46.5 12.4 1.4e-06 27.9 3.4 3.6 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Helicase_C PF00271.26 KRH94359.1 - 6.9e-12 45.0 0.0 1.8e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KRH94359.1 - 2.6e-07 30.2 0.3 9.5e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KRH94359.1 - 0.0016 18.5 0.3 0.0044 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KRH94359.1 - 0.0053 16.2 0.2 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KRH94359.1 - 0.0057 16.5 0.3 0.027 14.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain HA2 PF04408.18 KRH94359.1 - 0.01 15.8 0.2 0.038 13.9 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) Ribosomal_L18e PF00828.14 KRH94360.1 - 1.1e-24 87.2 1.1 1.3e-24 86.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DGOK PF05035.7 KRH94360.1 - 0.07 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase TRH PF05438.7 KRH94360.1 - 0.37 10.1 2.2 0.46 9.8 1.6 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) DEAD PF00270.24 KRH94361.1 - 1.7e-30 105.7 1.0 5.1e-30 104.1 0.7 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH94361.1 - 7.9e-19 67.3 0.0 2.4e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KRH94361.1 - 2.2e-12 46.3 0.4 7.3e-12 44.6 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KRH94361.1 - 1.7e-08 34.4 0.3 1.7e-08 34.4 0.2 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Cullin_Nedd8 PF10557.4 KRH94361.1 - 0.0069 16.1 0.4 0.044 13.6 0.3 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain AAA_19 PF13245.1 KRH94361.1 - 0.043 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain SecA_DEAD PF07517.9 KRH94361.1 - 0.053 12.7 2.1 3.4 6.8 0.0 3.6 4 0 0 4 4 4 0 SecA DEAD-like domain Flavi_DEAD PF07652.9 KRH94361.1 - 0.14 11.9 0.2 0.46 10.2 0.1 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain Med27 PF11571.3 KRH94361.1 - 0.19 11.8 1.0 4.2 7.5 0.3 2.6 2 0 0 2 2 2 0 Mediator complex subunit 27 CW_binding_2 PF04122.7 KRH94361.1 - 0.25 11.5 2.6 6.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 CTD_bind PF04818.8 KRH94361.1 - 2.1 8.6 7.3 0.32 11.2 0.2 3.1 3 0 0 3 3 3 0 RNA polymerase II-binding domain. zf-C4_Topoisom PF01396.14 KRH94362.1 - 0.0031 16.9 0.8 0.0084 15.5 0.4 1.9 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger DNA_ligase_ZBD PF03119.11 KRH94362.1 - 0.0043 16.7 1.0 0.013 15.1 0.7 1.8 1 1 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain T4_baseplate PF12322.3 KRH94362.1 - 0.0045 16.2 0.2 0.005 16.1 0.2 1.1 1 0 0 1 1 1 1 T4 bacteriophage base plate protein Zn-ribbon_8 PF09723.5 KRH94362.1 - 0.037 13.9 0.1 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KRH94362.1 - 0.055 13.1 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 KRH94362.1 - 0.065 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 KRH94362.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 rve PF00665.21 KRH94363.1 - 6.1e-10 39.2 0.1 3.3e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KRH94363.1 - 1.1e-05 24.8 0.1 2.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4537 PF15057.1 KRH94363.1 - 0.0097 15.6 0.3 0.016 14.9 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) Streptin-Immun PF11083.3 KRH94363.1 - 0.014 15.3 1.9 0.014 15.3 1.3 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF2533 PF10752.4 KRH94363.1 - 0.019 15.2 1.2 0.78 10.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) LOH1CR12 PF10158.4 KRH94363.1 - 0.038 13.7 0.5 0.038 13.7 0.4 1.6 2 0 0 2 2 2 0 Tumour suppressor protein YukC PF10140.4 KRH94367.1 - 0.13 10.7 1.7 0.17 10.4 0.2 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Lipoprotein_20 PF13942.1 KRH94368.1 - 0.032 13.7 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Syntaxin PF00804.20 KRH94368.1 - 0.41 10.8 3.4 0.52 10.5 2.3 1.2 1 0 0 1 1 1 0 Syntaxin Lebercilin PF15619.1 KRH94369.1 - 0.0035 16.7 4.5 0.0042 16.5 3.1 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.8 KRH94369.1 - 0.011 15.6 6.3 0.013 15.4 4.4 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4618 PF15397.1 KRH94369.1 - 0.015 14.6 3.8 0.02 14.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) RPN7 PF10602.4 KRH94369.1 - 0.031 13.6 0.4 0.041 13.2 0.3 1.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DUF2385 PF09539.5 KRH94369.1 - 0.051 13.9 0.5 0.064 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) CCDC92 PF14916.1 KRH94369.1 - 0.11 12.0 3.6 4.6 6.9 0.0 2.5 2 1 0 2 2 2 0 Coiled-coil domain of unknown function AAA_32 PF13654.1 KRH94369.1 - 0.12 10.9 1.8 0.13 10.8 1.3 1.0 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 KRH94369.1 - 0.15 10.4 4.5 0.16 10.3 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SufE PF02657.10 KRH94369.1 - 0.16 11.5 1.7 0.22 11.1 0.9 1.4 1 1 0 1 1 1 0 Fe-S metabolism associated domain DUF904 PF06005.7 KRH94369.1 - 0.22 11.8 5.2 4 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Gp-FAR-1 PF05823.7 KRH94369.1 - 0.27 11.1 3.8 1.2 9.0 0.1 2.0 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2051 PF09738.4 KRH94369.1 - 0.31 10.2 5.8 3.9 6.6 0.1 2.0 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) GrpE PF01025.14 KRH94369.1 - 0.35 10.3 3.5 0.43 10.1 2.4 1.1 1 0 0 1 1 1 0 GrpE Seryl_tRNA_N PF02403.17 KRH94369.1 - 0.38 10.7 4.7 0.66 10.0 3.3 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF573 PF04504.9 KRH94369.1 - 0.38 11.0 4.4 0.39 11.0 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF3847 PF12958.2 KRH94369.1 - 0.4 10.4 0.2 0.4 10.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) Nodulin_late PF07127.6 KRH94369.1 - 0.61 10.2 0.1 0.61 10.2 0.1 2.5 3 0 0 3 3 3 0 Late nodulin protein AKNA PF12443.3 KRH94369.1 - 1.3 9.0 8.3 0.93 9.5 2.6 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor YPEB PF14620.1 KRH94370.1 - 0.0014 17.6 3.5 0.0017 17.4 2.4 1.0 1 0 0 1 1 1 1 YpeB sporulation TBPIP PF07106.8 KRH94370.1 - 0.0019 17.7 6.0 0.0022 17.5 4.2 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_UL14 PF03580.9 KRH94370.1 - 0.0041 16.9 3.2 0.0046 16.7 2.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Cytochrom_C_2 PF01322.15 KRH94370.1 - 0.0092 16.5 1.4 0.011 16.2 1.0 1.1 1 0 0 1 1 1 1 Cytochrome C' AATF-Che1 PF13339.1 KRH94370.1 - 0.021 14.9 5.5 0.8 9.8 0.4 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Seryl_tRNA_N PF02403.17 KRH94370.1 - 0.022 14.7 6.3 0.031 14.3 4.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rogdi_lz PF10259.4 KRH94370.1 - 0.026 13.6 1.7 0.029 13.4 1.2 1.0 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein IncA PF04156.9 KRH94370.1 - 0.04 13.5 4.6 0.05 13.2 3.2 1.2 1 0 0 1 1 1 0 IncA protein DUF573 PF04504.9 KRH94370.1 - 0.043 14.1 3.0 0.082 13.1 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF3644 PF12358.3 KRH94370.1 - 0.065 13.5 0.7 0.39 11.0 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3644) PA26 PF04636.8 KRH94370.1 - 0.078 11.6 2.4 0.093 11.4 1.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Mod_r PF07200.8 KRH94370.1 - 0.09 12.6 6.1 0.14 12.1 4.2 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein 4HB_MCP_1 PF12729.2 KRH94370.1 - 0.092 12.0 5.1 0.14 11.4 3.5 1.3 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF342 PF03961.8 KRH94370.1 - 0.13 10.5 5.8 0.15 10.4 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 KRH94370.1 - 0.14 11.2 2.8 0.16 10.9 2.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FBP PF07299.6 KRH94370.1 - 0.14 11.4 1.7 0.33 10.2 1.0 1.7 1 1 1 2 2 2 0 Fibronectin-binding protein (FBP) Exonuc_VII_S PF02609.11 KRH94370.1 - 0.15 11.8 0.4 0.15 11.8 0.3 2.0 2 0 0 2 2 2 0 Exonuclease VII small subunit PspB PF06667.7 KRH94370.1 - 0.18 11.7 3.4 0.16 11.8 0.4 2.0 1 1 1 2 2 2 0 Phage shock protein B DUF4239 PF14023.1 KRH94370.1 - 0.2 10.9 0.7 0.26 10.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) CHASE3 PF05227.8 KRH94370.1 - 0.26 10.9 5.3 0.49 10.0 3.7 1.4 1 1 0 1 1 1 0 CHASE3 domain DUF4259 PF14078.1 KRH94370.1 - 0.27 11.7 3.7 0.27 11.7 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) FlgN PF05130.7 KRH94370.1 - 0.38 10.9 5.0 0.49 10.6 3.5 1.2 1 0 0 1 1 1 0 FlgN protein DASH_Dam1 PF08653.5 KRH94370.1 - 0.41 10.4 4.9 0.25 11.1 0.3 2.3 3 0 0 3 3 2 0 DASH complex subunit Dam1 DUF4613 PF15390.1 KRH94370.1 - 0.43 8.7 2.4 0.48 8.5 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4613) KilA-N PF04383.8 KRH94370.1 - 0.46 10.1 6.1 4.7 6.8 0.6 2.1 1 1 1 2 2 2 0 KilA-N domain Mnd1 PF03962.10 KRH94370.1 - 0.5 10.0 7.0 0.54 9.8 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family DUF2407_C PF13373.1 KRH94370.1 - 0.76 9.6 3.8 1 9.2 2.5 1.4 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF972 PF06156.8 KRH94370.1 - 1.2 9.4 5.5 3.9 7.8 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Uds1 PF15456.1 KRH94370.1 - 1.6 8.7 6.4 11 5.9 4.4 1.9 1 1 1 2 2 2 0 Up-regulated During Septation DUF4163 PF13739.1 KRH94370.1 - 5.3 7.8 7.2 3.3 8.5 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Vasculin PF15337.1 KRH94370.1 - 9.7 6.7 8.9 3.5 8.1 3.8 1.9 1 1 1 2 2 2 0 Vascular protein family Vasculin-like 1 DUF4187 PF13821.1 KRH94371.1 - 5.3e-06 25.9 5.4 1.3e-05 24.6 3.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 KRH94371.1 - 0.0033 17.0 0.1 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH94371.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 KRH94371.1 - 0.038 14.3 1.5 0.038 14.3 1.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Hemerythrin PF01814.18 KRH94371.1 - 0.093 12.8 0.1 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain zf-Di19 PF05605.7 KRH94371.1 - 1.4 9.0 4.4 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 KRH94371.1 - 2 8.5 9.1 1.1 9.3 2.6 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KRH94371.1 - 2.7 8.5 8.6 1.2 9.6 1.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger LSM PF01423.17 KRH94372.1 - 4.4e-11 42.1 0.1 6.7e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KRH94372.1 - 0.0028 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain SMC_N PF02463.14 KRH94373.1 - 3.1e-27 95.2 0.3 6e-27 94.2 0.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TBPIP PF07106.8 KRH94373.1 - 0.0042 16.6 9.9 0.0042 16.6 6.8 6.8 2 2 5 8 8 8 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 KRH94373.1 - 0.0057 16.4 7.7 0.0057 16.4 5.4 5.8 3 1 2 5 5 5 1 TPR/MLP1/MLP2-like protein AAA_29 PF13555.1 KRH94373.1 - 0.011 15.3 0.2 0.024 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KRH94373.1 - 0.02 15.0 0.6 1.8 8.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain DUF4326 PF14216.1 KRH94373.1 - 5.6 7.6 7.5 40 4.8 0.2 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4326) NIF PF03031.13 KRH94374.1 - 5.8e-10 39.0 0.9 1.2e-09 38.0 0.6 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2817 PF10994.3 KRH94374.1 - 0.0035 16.4 0.3 0.0056 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) Sedlin_N PF04628.8 KRH94375.1 - 2.7e-08 33.7 1.1 3.1e-08 33.5 0.8 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L14 PF00238.14 KRH94376.1 - 0.019 14.7 0.1 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L14p/L23e zf-RING_6 PF14835.1 KRH94378.1 - 0.067 12.9 1.8 0.07 12.9 1.2 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ecl1 PF12855.2 KRH94378.1 - 5.4 6.3 10.1 2.5 7.4 0.7 2.1 1 1 1 2 2 2 0 Life-span regulatory factor zf-BED PF02892.10 KRH94378.1 - 9.1 6.1 8.9 0.54 10.0 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger MS_channel PF00924.13 KRH94379.1 - 4.5e-15 55.5 0.1 4.5e-15 55.5 0.1 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KRH94379.1 - 2.1e-05 23.4 1.6 5.9e-05 22.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KRH94379.1 - 8.5e-05 22.1 0.1 0.00053 19.6 0.1 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 KRH94379.1 - 0.0053 16.3 0.1 0.015 14.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KRH94379.1 - 0.0092 16.0 0.2 0.046 13.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KRH94379.1 - 0.018 14.3 0.2 0.064 12.6 0.1 2.0 1 0 0 1 1 1 0 EF hand NDUF_B12 PF08122.7 KRH94379.1 - 0.059 13.1 4.5 2 8.1 0.2 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Arm PF00514.18 KRH94381.1 - 9.8e-31 104.5 10.9 6.4e-10 38.4 0.0 8.1 8 2 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KRH94381.1 - 6.6e-07 29.6 0.0 0.00015 22.1 0.0 4.6 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.1 KRH94381.1 - 3.2e-06 27.3 0.0 0.015 15.5 0.0 3.9 3 2 0 3 3 3 2 HEAT repeats IBB PF01749.15 KRH94381.1 - 0.00025 21.1 2.9 0.00063 19.8 2.0 1.8 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 KRH94381.1 - 0.00026 20.8 2.4 3.9 7.4 0.0 4.8 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 KRH94381.1 - 0.047 13.7 7.4 5.5 7.3 0.0 5.8 8 0 0 8 8 8 0 HEAT repeat VCBS PF13517.1 KRH94382.1 - 2.3e-06 27.8 0.4 0.0054 17.0 0.0 3.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KRH94382.1 - 0.00051 19.6 1.7 0.12 12.0 0.1 2.5 2 0 0 2 2 2 2 FG-GAP repeat NMD3 PF04981.8 KRH94383.1 - 1.3e-50 171.7 12.9 1.9e-50 171.2 9.0 1.2 1 0 0 1 1 1 1 NMD3 family PRTase_2 PF15609.1 KRH94383.1 - 0.11 11.7 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase RNA_pol_3_Rpc31 PF11705.3 KRH94384.1 - 0.0036 17.2 0.2 0.0039 17.1 0.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2410 PF10307.4 KRH94384.1 - 0.024 14.0 0.2 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2410) Arrestin_N PF00339.24 KRH94385.1 - 0.00033 20.5 1.0 0.0016 18.2 0.1 2.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain zf-CSL PF05207.8 KRH94386.1 - 5.4e-21 73.8 0.5 8.3e-21 73.2 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.1 KRH94386.1 - 0.019 14.5 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 KRH94386.1 - 0.032 13.8 0.2 0.057 13.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KRH94386.1 - 0.13 11.9 0.3 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L6 PF00347.18 KRH94387.1 - 3.8e-18 65.7 0.6 1.8e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 RVT_1 PF00078.22 KRH94389.1 - 1.7e-18 66.7 0.1 2.3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TRI5 PF06330.6 KRH94389.1 - 0.01 14.5 0.2 0.017 13.8 0.1 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Glucosaminidase PF01832.15 KRH94390.1 - 0.0064 16.6 0.8 0.012 15.7 0.6 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase DUF3486 PF11985.3 KRH94390.1 - 0.045 13.8 0.5 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) DUF1908 PF08926.6 KRH94390.1 - 0.12 11.0 1.9 0.17 10.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Cauli_DNA-bind PF03310.8 KRH94390.1 - 0.85 9.4 5.0 0.76 9.6 1.5 2.2 2 1 1 3 3 3 0 Caulimovirus DNA-binding protein Peptidase_C34 PF05413.6 KRH94391.1 - 0.19 11.7 2.6 1.4 9.0 0.1 2.8 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase LSM PF01423.17 KRH94394.1 - 3.3e-10 39.3 0.0 4.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF1510 PF07423.6 KRH94395.1 - 0.41 9.9 24.3 0.54 9.5 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF572 PF04502.8 KRH94395.1 - 0.72 9.0 17.9 0.86 8.7 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3c_N PF05470.7 KRH94395.1 - 0.76 7.7 21.7 0.89 7.5 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 KRH94395.1 - 1.3 7.0 20.5 1.4 6.8 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 KRH94395.1 - 1.9 8.4 27.0 3 7.8 18.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PRTP PF01366.13 KRH94395.1 - 2.1 6.2 8.8 2.3 6.1 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DDHD PF02862.12 KRH94395.1 - 2.4 7.8 14.0 2.8 7.6 9.7 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KRH94395.1 - 2.7 5.7 26.7 3.3 5.4 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 KRH94395.1 - 3.6 6.6 22.2 3.9 6.5 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Band_3_cyto PF07565.8 KRH94395.1 - 4 6.8 9.5 4.5 6.7 6.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FLO_LFY PF01698.11 KRH94395.1 - 5.7 5.6 13.2 6.4 5.5 9.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 KRH94395.1 - 8.3 5.5 19.9 11 5.1 13.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger G-7-MTase PF12803.2 KRH94395.1 - 9 5.3 7.1 10 5.1 4.9 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF1706 PF08020.6 KRH94396.1 - 0.076 12.5 0.4 0.12 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) E1-E2_ATPase PF00122.15 KRH94397.1 - 1.2e-15 57.2 12.5 2.1e-09 36.7 0.2 3.1 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 KRH94397.1 - 2.9e-15 57.2 0.0 2e-14 54.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KRH94397.1 - 9e-10 39.0 0.0 2.4e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KRH94397.1 - 6.6e-09 35.6 0.1 5.9e-08 32.5 0.0 2.6 2 1 1 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2951 PF11166.3 KRH94398.1 - 0.022 14.6 2.3 0.024 14.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) UQ_con PF00179.21 KRH94400.1 - 4.7e-39 133.0 0.1 5.7e-39 132.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KRH94400.1 - 0.0065 16.3 0.6 0.027 14.3 0.4 2.1 1 1 0 1 1 1 1 RWD domain Hexokinase_1 PF00349.16 KRH94401.1 - 1.2e-18 67.1 0.6 3.4e-18 65.7 0.1 1.8 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 KRH94401.1 - 6.8e-09 35.2 0.1 2.5e-06 26.8 0.1 2.4 1 1 1 2 2 2 2 Hexokinase StbA PF06406.6 KRH94401.1 - 0.002 17.0 0.5 0.092 11.6 0.0 2.4 2 0 0 2 2 2 2 StbA protein DHFR_1 PF00186.14 KRH94402.1 - 9.2e-23 80.5 0.3 1e-22 80.4 0.2 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Ribosomal_S4e PF00900.15 KRH94403.1 - 2.6e-20 71.8 0.2 5.5e-20 70.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KRH94403.1 - 4.5e-17 61.6 4.7 6.4e-17 61.1 2.5 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 KRH94403.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KTI12 PF08433.5 KRH94404.1 - 0.0065 15.7 3.8 2.1 7.4 0.2 3.1 1 1 2 3 3 3 2 Chromatin associated protein KTI12 Psb28 PF03912.9 KRH94404.1 - 0.053 13.4 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Psb28 protein Cnd1 PF12717.2 KRH94405.1 - 7.2e-08 32.4 38.9 4.5e-06 26.6 3.7 5.0 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KRH94405.1 - 0.0061 16.5 0.1 12 6.2 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KRH94405.1 - 0.056 13.7 0.1 0.34 11.2 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats DUF2435 PF10363.4 KRH94405.1 - 0.43 10.5 9.1 0.11 12.4 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) zf-DHHC PF01529.15 KRH94406.1 - 1.5 8.1 4.1 1.6 8.1 2.9 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase DDE_3 PF13358.1 KRH94407.1 - 0.0006 19.5 0.0 0.00073 19.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Shugoshin_N PF07558.6 KRH94409.1 - 0.028 14.1 1.5 0.037 13.7 1.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DDE_Tnp_IS1595 PF12762.2 KRH94410.1 - 1.4e-07 31.5 0.0 1.5e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain Nucleo_LEF-12 PF06256.6 KRH94411.1 - 0.034 13.9 1.1 0.056 13.2 0.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein N_NLPC_P60 PF12912.2 KRH94415.1 - 0.05 13.7 0.7 0.055 13.5 0.5 1.2 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term CS PF04969.11 KRH94416.1 - 2.8e-11 43.8 2.0 5.9e-11 42.7 1.4 1.6 1 0 0 1 1 1 1 CS domain Peptidase_M1 PF01433.15 KRH94418.1 - 7.9e-109 364.2 15.8 3e-99 332.7 8.7 4.0 3 1 0 3 3 3 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 KRH94418.1 - 1.7e-15 57.2 0.4 1.7e-14 53.9 0.2 2.2 1 1 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 KRH94418.1 - 5.5e-15 55.4 0.2 4.5e-13 49.1 0.2 2.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain SprT-like PF10263.4 KRH94418.1 - 0.0003 20.4 0.0 0.00081 19.0 0.0 1.7 1 0 0 1 1 1 1 SprT-like family DUF2265 PF10023.4 KRH94418.1 - 0.00092 18.4 2.3 0.002 17.3 1.6 1.5 1 0 0 1 1 1 1 Predicted aminopeptidase (DUF2265) Trypan_PARP PF05887.6 KRH94418.1 - 0.63 9.8 10.4 1.3 8.8 7.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L16 PF00252.13 KRH94419.1 - 4.7e-28 97.5 1.0 6.1e-28 97.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ank_2 PF12796.2 KRH94422.1 - 0.0062 16.8 0.1 0.013 15.8 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KRH94422.1 - 0.014 15.1 0.0 0.079 12.8 0.0 2.2 2 1 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 KRH94422.1 - 0.019 15.1 0.0 0.53 10.6 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat TFIIF_beta PF02270.10 KRH94423.1 - 7.4e-36 124.3 4.5 1e-28 100.9 0.9 2.0 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit DEAD PF00270.24 KRH94427.1 - 3.5e-33 114.4 0.1 6.2e-31 107.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH94427.1 - 3.1e-19 68.6 0.6 8.7e-19 67.1 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KRH94427.1 - 1.6e-05 24.8 0.1 1.6e-05 24.8 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KRH94427.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DUF3106 PF11304.3 KRH94427.1 - 0.0071 16.7 1.1 0.15 12.4 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3106) Imm47 PF15586.1 KRH94427.1 - 0.053 13.3 0.5 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Immunity protein 47 AAA_22 PF13401.1 KRH94427.1 - 0.12 12.4 1.9 0.53 10.4 0.0 2.8 4 0 0 4 4 4 0 AAA domain Ribosomal_L3 PF00297.17 KRH94427.1 - 0.22 10.9 1.1 0.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L3 DUF788 PF05620.6 KRH94429.1 - 8.7e-11 41.9 7.2 1.1e-10 41.6 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) EI24 PF07264.6 KRH94429.1 - 0.019 14.4 7.2 0.025 14.0 5.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1673 PF07895.6 KRH94429.1 - 0.69 9.4 9.0 0.12 11.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) MIR PF02815.14 KRH94431.1 - 0.00065 19.2 0.1 0.0012 18.4 0.1 1.6 1 1 0 1 1 1 1 MIR domain AAA_11 PF13086.1 KRH94433.1 - 2.2e-22 79.8 1.6 6.1e-22 78.3 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.1 KRH94433.1 - 3.9e-22 78.6 1.9 1.5e-21 76.7 1.3 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KRH94433.1 - 1.7e-10 40.8 6.5 0.0083 15.6 0.0 4.5 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KRH94433.1 - 4.8e-08 32.6 0.0 9.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KRH94433.1 - 1.7e-06 27.7 0.0 4.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KRH94433.1 - 8.8e-06 25.8 0.0 6.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KRH94433.1 - 2.7e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KRH94433.1 - 0.00076 19.7 0.0 0.0075 16.5 0.0 2.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH94433.1 - 0.0014 19.4 0.3 0.0071 17.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain SRP54 PF00448.17 KRH94433.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 KRH94433.1 - 0.034 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KRH94433.1 - 0.037 13.7 0.5 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KRH94433.1 - 0.15 11.9 0.0 0.58 10.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KRH94433.1 - 0.22 11.4 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Glucosamine_iso PF01182.15 KRH94434.1 - 1e-20 74.3 0.1 3.3e-15 56.3 0.0 2.6 1 1 2 3 3 3 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PseudoU_synth_1 PF01416.15 KRH94435.1 - 1e-17 64.4 2.4 1.4e-11 44.7 0.0 3.8 4 1 0 4 4 4 2 tRNA pseudouridine synthase Ribosomal_S10 PF00338.17 KRH94436.1 - 1.2e-12 47.4 0.0 1.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DDE_Tnp_IS1595 PF12762.2 KRH94437.1 - 2.4e-14 53.4 0.0 2.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 KRH94438.1 - 5.5e-22 78.1 0.2 7.4e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Corona_NS4 PF03905.8 KRH94444.1 - 0.032 14.0 1.6 0.044 13.5 0.2 1.8 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 RVT_1 PF00078.22 KRH94445.1 - 7.3e-23 81.0 0.6 1.1e-22 80.5 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UcrQ PF02939.11 KRH94445.1 - 0.0047 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 UcrQ family eIF3g PF12353.3 KRH94446.1 - 0.00087 19.2 6.8 0.0011 18.9 3.2 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Thioredoxin_8 PF13905.1 KRH94447.1 - 0.083 13.0 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like DUF3887 PF13026.1 KRH94448.1 - 0.0021 18.2 8.8 0.0033 17.6 6.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3887) ERO1 PF04137.10 KRH94448.1 - 0.04 12.9 0.6 0.047 12.7 0.4 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Thg1C PF14413.1 KRH94448.1 - 0.88 9.2 4.6 1.1 9.0 3.2 1.1 1 0 0 1 1 1 0 Thg1 C terminal domain NAPRTase PF04095.11 KRH94448.1 - 0.89 8.7 5.5 43 3.2 3.8 2.0 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Imm6 PF14434.1 KRH94450.1 - 0.0022 17.7 0.2 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 Immunity protein Imm6 zf-HC5HC2H_2 PF13832.1 KRH94452.1 - 8.3e-23 80.4 7.6 8.3e-23 80.4 5.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KRH94452.1 - 3.1e-13 49.6 5.9 3.1e-13 49.6 4.1 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KRH94452.1 - 9.6e-13 47.2 2.4 9.6e-13 47.2 1.6 2.4 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.20 KRH94452.1 - 3.9e-11 42.7 1.4 1.2e-10 41.1 0.3 2.4 2 1 0 2 2 2 1 Bromodomain PHD PF00628.24 KRH94452.1 - 5.4e-09 35.6 3.4 5.4e-09 35.6 2.4 3.7 3 1 0 3 3 3 2 PHD-finger EPL1 PF10513.4 KRH94452.1 - 1.1e-05 25.7 0.5 1.1e-05 25.7 0.4 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-PHD-like PF15446.1 KRH94452.1 - 0.0039 16.5 0.5 0.0039 16.5 0.4 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KRH94452.1 - 0.033 13.9 0.1 0.033 13.9 0.1 3.9 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1-E2_ATPase PF00122.15 KRH94453.1 - 1.1e-51 175.0 5.1 2.5e-51 173.9 3.6 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KRH94453.1 - 4e-27 94.9 7.7 4e-27 94.9 5.4 3.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KRH94453.1 - 1.5e-22 81.1 0.0 3.7e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KRH94453.1 - 2.1e-14 53.2 0.0 6e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KRH94453.1 - 6.6e-14 52.5 0.1 2.4e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KRH94453.1 - 0.0077 15.6 0.0 0.035 13.5 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KRH94453.1 - 0.034 13.7 5.1 0.056 13.0 0.1 3.4 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KRH94453.1 - 0.06 13.5 0.0 0.22 11.7 0.0 1.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase UDG PF03167.14 KRH94454.1 - 1.4e-25 89.5 0.1 2.9e-25 88.5 0.0 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Lactamase_B PF00753.22 KRH94456.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KRH94456.1 - 0.002 17.6 0.1 0.0045 16.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CPSF100_C PF13299.1 KRH94456.1 - 0.026 14.7 0.1 0.098 12.8 0.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal 2-Hacid_dh_C PF02826.14 KRH94456.1 - 0.15 11.2 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CaM_binding PF07839.6 KRH94458.1 - 0.032 14.4 2.3 0.038 14.2 1.6 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain IFN-gamma PF00714.12 KRH94458.1 - 0.079 12.7 2.8 0.082 12.7 1.9 1.0 1 0 0 1 1 1 0 Interferon gamma APG9 PF04109.11 KRH94459.1 - 1.2e-06 27.7 8.0 1.2e-06 27.7 5.6 2.7 2 1 0 2 2 2 1 Autophagy protein Apg9 Hydrolase PF00702.21 KRH94461.1 - 6.9e-17 62.5 0.0 1.9e-16 61.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KRH94461.1 - 4.1e-14 52.1 0.1 4.1e-14 52.1 0.0 3.4 4 0 0 4 4 4 1 E1-E2 ATPase HAD PF12710.2 KRH94461.1 - 1.7e-13 51.1 0.0 3.9e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KRH94461.1 - 2.6e-05 24.1 0.2 0.00043 20.1 0.0 2.6 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit EnY2 PF10163.4 KRH94462.1 - 0.0018 18.1 0.1 0.0021 17.9 0.1 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2680 PF10925.3 KRH94462.1 - 0.035 13.9 0.9 7.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF2014 PF09427.5 KRH94462.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) M11L PF11099.3 KRH94462.1 - 0.46 10.2 3.9 0.77 9.4 2.2 1.6 1 1 1 2 2 2 0 Apoptosis regulator M11L like Helicase_C_3 PF13625.1 KRH94463.1 - 3.4e-24 85.0 0.0 7.4e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KRH94463.1 - 3.9e-14 52.9 2.9 9.8e-14 51.5 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KRH94463.1 - 2.7e-11 43.1 0.0 8.4e-11 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KRH94463.1 - 2.9e-09 36.1 0.2 9.1e-09 34.5 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KRH94463.1 - 1.8e-07 30.8 0.1 3.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPC22 PF04573.7 KRH94464.1 - 1.2e-10 40.9 2.8 1.7e-10 40.4 1.9 1.3 1 0 0 1 1 1 1 Signal peptidase subunit TruD PF01142.13 KRH94465.1 - 2.2e-51 174.7 6.7 3.4e-21 75.3 0.1 4.1 2 1 2 4 4 4 4 tRNA pseudouridine synthase D (TruD) DUF4434 PF14488.1 KRH94465.1 - 0.082 12.6 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) EndoU_bacteria PF14436.1 KRH94465.1 - 0.85 9.4 5.5 0.4 10.5 0.3 2.6 2 1 1 3 3 3 0 Bacterial EndoU nuclease Sec61_beta PF03911.11 KRH94466.1 - 3.6e-06 26.6 2.3 3.6e-06 26.6 1.6 2.0 2 0 0 2 2 2 1 Sec61beta family TcpE PF12648.2 KRH94466.1 - 0.019 15.0 2.2 0.021 14.9 1.5 1.1 1 0 0 1 1 1 0 TcpE family DUF2208 PF09973.4 KRH94466.1 - 0.033 13.4 3.1 0.037 13.2 2.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF2207 PF09972.4 KRH94466.1 - 0.23 10.0 1.1 0.22 10.0 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.7 KRH94466.1 - 0.91 9.2 6.8 5.4 6.7 4.8 1.9 1 1 0 1 1 1 0 Ninjurin DDE_Tnp_IS1595 PF12762.2 KRH94468.1 - 0.011 15.5 0.2 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 ISXO2-like transposase domain Asp_protease_2 PF13650.1 KRH94473.1 - 8.8e-05 22.9 0.0 0.0002 21.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94473.1 - 0.01 15.6 0.1 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH94473.1 - 0.077 12.9 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Phage_pRha PF09669.5 KRH94474.1 - 0.057 13.7 0.5 1.7 9.0 0.1 2.1 1 1 1 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Polysacc_deac_1 PF01522.16 KRH94475.1 - 5.3e-08 32.5 0.1 1.4e-07 31.2 0.0 1.6 1 1 1 2 2 2 1 Polysaccharide deacetylase DUF1633 PF07794.6 KRH94475.1 - 0.013 13.4 0.0 0.017 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) CTP_synth_N PF06418.9 KRH94476.1 - 9e-43 146.3 5.2 6.9e-41 140.1 0.6 3.2 2 1 0 2 2 2 2 CTP synthase N-terminus GATase PF00117.23 KRH94476.1 - 1.2e-30 106.4 1.4 1.4e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KRH94476.1 - 0.00049 19.5 0.0 0.067 12.6 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 TatC PF00902.13 KRH94477.1 - 0.0058 16.0 0.6 0.009 15.4 0.4 1.2 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) ALO PF04030.9 KRH94477.1 - 0.092 12.3 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase Sigma_reg_N PF13800.1 KRH94477.1 - 0.19 11.7 1.3 0.39 10.7 0.9 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal B12D PF06522.6 KRH94478.1 - 0.0061 16.2 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MRAP PF15183.1 KRH94478.1 - 0.071 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF3357 PF11837.3 KRH94478.1 - 0.088 12.6 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 KRH94478.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myb_DNA-binding PF00249.26 KRH94480.1 - 0.00089 19.2 0.0 0.61 10.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KRH94480.1 - 0.06 13.4 0.4 3.2 7.9 0.0 3.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain Rap1_C PF11626.3 KRH94480.1 - 0.062 13.1 0.2 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AMP-binding PF00501.23 KRH94481.1 - 1.7e-41 142.0 0.0 5.4e-34 117.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme DUF2207 PF09972.4 KRH94482.1 - 0.018 13.6 0.8 0.019 13.5 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HlyIII PF03006.15 KRH94483.1 - 0.27 10.6 4.0 0.35 10.2 2.8 1.1 1 0 0 1 1 1 0 Haemolysin-III related RVT_1 PF00078.22 KRH94484.1 - 1.5e-19 70.2 0.0 4.3e-19 68.7 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH94484.1 - 4.4e-17 62.3 0.1 8.9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 KRH94485.1 - 3.9e-06 26.6 0.8 1.1e-05 25.2 0.1 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH94485.1 - 8.5e-06 26.1 0.0 2.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94485.1 - 3.8e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KRH94485.1 - 5.1e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 KRH94485.1 - 0.001 18.4 1.6 0.0021 17.4 0.2 2.2 2 0 0 2 2 2 1 Ty3 transposon peptidase RVP_2 PF08284.6 KRH94485.1 - 0.0037 17.1 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Amnionless PF14828.1 KRH94486.1 - 0.00075 18.1 0.0 0.00085 17.9 0.0 1.0 1 0 0 1 1 1 1 Amnionless Securin PF04856.8 KRH94486.1 - 0.00094 18.9 7.0 0.0016 18.1 4.9 1.3 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor DUF2207 PF09972.4 KRH94486.1 - 0.0086 14.7 0.3 0.01 14.4 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF751 PF05421.6 KRH94486.1 - 0.055 13.7 1.6 0.12 12.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF1272 PF06906.6 KRH94487.1 - 2.4 8.0 5.9 1.2 9.0 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) Cys_rich_KTR PF14205.1 KRH94487.1 - 6.4 6.3 10.6 0.67 9.4 0.9 3.1 3 1 1 4 4 4 0 Cysteine-rich KTR PTN_MK_C PF01091.13 KRH94487.1 - 7.3 6.6 8.4 20 5.2 0.2 3.2 2 1 1 3 3 3 0 PTN/MK heparin-binding protein family, C-terminal domain HTH_29 PF13551.1 KRH94488.1 - 2.5e-05 24.3 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KRH94488.1 - 0.00061 19.3 0.3 0.0012 18.3 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KRH94488.1 - 0.019 15.7 0.1 0.13 13.0 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain CYTL1 PF15153.1 KRH94488.1 - 0.032 13.9 0.8 0.04 13.6 0.5 1.1 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF3013 PF11217.3 KRH94488.1 - 0.05 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3013) DUF1497 PF07384.6 KRH94488.1 - 0.12 12.5 0.2 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) PRANC PF09372.5 KRH94491.1 - 0.12 12.3 11.3 0.13 12.2 3.1 2.2 1 1 1 2 2 2 0 PRANC domain RVT_1 PF00078.22 KRH94493.1 - 4.4e-25 88.3 0.1 7e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.9 KRH94493.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 PRELI-like family Helitron_like_N PF14214.1 KRH94494.1 - 3.6e-08 33.3 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.1 KRH94495.1 - 0.0034 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KRH94496.1 - 9.3e-37 126.8 0.0 1.2e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KRH94496.1 - 3.8e-09 36.3 0.0 7.6e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KRH94496.1 - 0.00016 21.7 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KRH94496.1 - 0.0008 19.3 0.1 0.013 15.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KRH94496.1 - 0.0012 18.4 0.2 0.73 9.3 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KRH94496.1 - 0.0026 17.4 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KRH94496.1 - 0.0046 16.9 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 KRH94496.1 - 0.0082 15.1 0.0 0.081 11.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KRH94496.1 - 0.012 15.7 0.1 0.038 14.1 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KRH94496.1 - 0.037 13.2 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.11 KRH94496.1 - 0.044 12.6 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase ResIII PF04851.10 KRH94496.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.9 KRH94496.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain KaiC PF06745.8 KRH94496.1 - 0.071 12.2 0.4 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 KRH94496.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 KRH94496.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1253 PF06862.7 KRH94496.1 - 0.18 10.1 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) UvrD_C_2 PF13538.1 KRH94497.1 - 2.9e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 KRH94497.1 - 0.0002 19.2 0.0 0.00022 19.1 0.0 1.0 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KRH94497.1 - 0.0019 17.7 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF736 PF05284.7 KRH94497.1 - 0.059 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF736) tify PF06200.9 KRH94498.1 - 0.16 11.2 0.6 2.1 7.6 0.0 2.4 3 0 0 3 3 3 0 tify domain IFNGR1 PF07140.6 KRH94499.1 - 0.04 13.6 0.4 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) RVT_1 PF00078.22 KRH94500.1 - 0.0068 15.7 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KRH94501.1 - 0.01 16.1 0.3 0.02 15.2 0.2 1.5 1 1 0 1 1 1 0 RNase H Frizzled PF01534.12 KRH94501.1 - 0.022 13.5 0.1 0.03 13.1 0.1 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Glyco_tranf_2_4 PF13704.1 KRH94501.1 - 0.047 14.0 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 RVT_3 PF13456.1 KRH94501.1 - 0.056 13.2 0.3 0.18 11.5 0.2 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like DDE_Tnp_IS1595 PF12762.2 KRH94504.1 - 3.6e-05 23.6 0.3 4.1e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Urm1 PF09138.6 KRH94505.1 - 2.8e-07 30.5 0.3 2.8e-07 30.5 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Yos1 PF08571.5 KRH94506.1 - 2.2e-17 62.8 1.6 2.6e-17 62.6 1.1 1.0 1 0 0 1 1 1 1 Yos1-like DUF4064 PF13273.1 KRH94506.1 - 0.12 12.4 1.8 0.16 12.0 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) SecY PF00344.15 KRH94507.1 - 2.8e-71 240.2 20.0 3.4e-71 239.9 13.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KRH94507.1 - 7.5e-16 57.3 0.3 1.4e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 Plug domain of Sec61p DNA_alkylation PF08713.6 KRH94508.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme Formyl_trans_C PF02911.13 KRH94509.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1456 PF07308.8 KRH94509.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) MS_channel PF00924.13 KRH94509.1 - 0.24 10.6 3.0 5.8 6.1 0.3 2.3 1 1 2 3 3 3 0 Mechanosensitive ion channel BPL_C PF02237.12 KRH94510.1 - 0.0023 17.6 0.2 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DcpS PF05652.7 KRH94510.1 - 0.27 11.6 2.0 3.7 7.9 0.3 2.5 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal Formyl_trans_C PF02911.13 KRH94511.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF1456 PF07308.8 KRH94511.1 - 0.058 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) MS_channel PF00924.13 KRH94511.1 - 0.24 10.6 3.0 5.8 6.1 0.3 2.3 1 1 2 3 3 3 0 Mechanosensitive ion channel Transketolase_C PF02780.15 KRH94513.1 - 3.5e-35 120.6 0.0 4.6e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KRH94514.1 - 7.4e-34 116.7 0.0 8.3e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain zf-C3HC4_3 PF13920.1 KRH94516.1 - 1.6e-08 34.0 9.8 3.7e-08 32.9 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH94516.1 - 3.3e-08 33.4 11.8 3.3e-08 33.4 8.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH94516.1 - 2.4e-07 30.3 9.4 5.8e-07 29.1 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KRH94516.1 - 3.5e-07 29.7 12.1 1e-06 28.3 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KRH94516.1 - 6.3e-06 25.9 8.0 1.3e-05 24.9 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KRH94516.1 - 0.00032 20.4 3.7 0.00069 19.3 2.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KRH94516.1 - 0.00043 20.0 5.8 0.0015 18.3 4.1 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KRH94516.1 - 0.00046 19.8 5.0 0.00046 19.8 3.4 2.6 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KRH94516.1 - 0.0011 18.4 2.0 0.0026 17.2 1.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.1 KRH94516.1 - 0.33 11.3 3.5 19 5.7 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Vpu PF00558.14 KRH94516.1 - 0.48 10.0 8.5 0.65 9.5 3.4 3.1 2 1 0 2 2 2 0 Vpu protein zf-RING_4 PF14570.1 KRH94516.1 - 1.8 8.2 11.8 36 4.0 8.1 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1529 PF07485.6 KRH94518.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) WD40 PF00400.27 KRH94519.1 - 1.2e-37 126.4 11.7 1.3e-13 50.2 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KRH94519.1 - 3.3e-36 124.4 4.5 3.3e-36 124.4 3.1 2.7 3 0 0 3 3 3 1 WD40 associated region in TFIID subunit Proteasome PF00227.21 KRH94520.1 - 1.5e-23 83.0 0.1 1.2e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit TRAM_LAG1_CLN8 PF03798.11 KRH94521.1 - 6.2e-32 110.7 30.7 8.4e-32 110.3 21.3 1.2 1 0 0 1 1 1 1 TLC domain CelD_N PF02927.9 KRH94522.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase TRAPP PF04051.11 KRH94523.1 - 0.00097 18.6 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glutaredoxin PF00462.19 KRH94524.1 - 4.6e-07 29.7 1.6 1.6e-06 28.0 0.0 2.6 3 0 0 3 3 3 1 Glutaredoxin DDE_Tnp_IS1595 PF12762.2 KRH94526.1 - 1.3e-23 83.5 0.6 1.7e-23 83.0 0.4 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain Sof1 PF04158.9 KRH94527.1 - 0.94 9.5 4.0 1.8 8.6 2.8 1.4 1 1 0 1 1 1 0 Sof1-like domain DUF257 PF03192.8 KRH94531.1 - 0.097 11.9 0.5 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Folate_rec PF03024.9 KRH94535.1 - 0.032 13.8 0.3 0.032 13.8 0.2 1.0 1 0 0 1 1 1 0 Folate receptor family DUF3609 PF12259.3 KRH94538.1 - 0.00035 19.3 0.0 0.00069 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF3519 PF12033.3 KRH94540.1 - 1.1 9.4 7.6 1.5 9.0 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3519) DUF3816 PF12822.2 KRH94541.1 - 0.1 12.4 1.1 0.21 11.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF2846 PF11008.3 KRH94542.1 - 0.024 14.4 0.0 0.098 12.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2846) Endotoxin_M PF00555.14 KRH94542.1 - 0.9 9.3 10.3 0.022 14.5 1.6 2.0 1 1 1 2 2 2 0 delta endotoxin O-ag_pol_Wzy PF14296.1 KRH94543.1 - 0.034 12.7 0.1 0.045 12.3 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DDE_3 PF13358.1 KRH94547.1 - 2.1e-20 72.9 0.0 2.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KRH94547.1 - 5.4e-14 52.0 1.1 2.8e-12 46.5 0.2 2.3 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 KRH94547.1 - 9.2e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 KRH94547.1 - 2.3e-05 24.1 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain rve PF00665.21 KRH94547.1 - 0.00068 19.7 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 KRH94547.1 - 0.00093 18.7 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.8 KRH94547.1 - 0.0042 16.4 0.0 0.018 14.4 0.0 2.1 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.1 KRH94547.1 - 0.0044 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 KRH94547.1 - 0.021 14.5 0.1 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_3 PF01381.17 KRH94547.1 - 0.057 13.2 0.4 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix MarR_2 PF12802.2 KRH94547.1 - 0.15 11.7 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 MarR family TCR PF03638.10 KRH94548.1 - 2 8.3 14.1 1.2 8.9 4.5 2.2 2 0 0 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain DUF4448 PF14610.1 KRH94549.1 - 0.0036 16.8 0.1 0.0042 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3609 PF12259.3 KRH94549.1 - 0.017 13.8 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) FSA_C PF10479.4 KRH94549.1 - 0.028 12.5 0.4 0.035 12.1 0.3 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FUN14 PF04930.10 KRH94549.1 - 0.27 11.5 2.7 0.68 10.2 1.8 1.8 1 1 0 1 1 1 0 FUN14 family SWIM PF04434.12 KRH94550.1 - 0.071 12.5 1.3 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 SWIM zinc finger DUF4044 PF13253.1 KRH94550.1 - 0.084 12.0 0.3 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Gp58 PF07902.6 KRH94552.1 - 0.027 12.7 0.0 0.027 12.7 0.0 1.0 1 0 0 1 1 1 0 gp58-like protein DUF2935 PF11155.3 KRH94552.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3888 PF13027.1 KRH94552.1 - 0.092 12.6 0.3 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) OspE PF02471.12 KRH94553.1 - 0.071 12.9 0.5 0.35 10.7 0.0 2.4 3 0 0 3 3 3 0 Borrelia outer surface protein E ECF-ribofla_trS PF07155.7 KRH94553.1 - 0.16 11.7 0.2 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DUF2069 PF09842.4 KRH94554.1 - 0.72 9.8 10.2 1 9.3 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) Enolase_C PF00113.17 KRH94555.1 - 7.4e-80 268.0 0.1 1.1e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KRH94555.1 - 4.5e-30 104.2 0.0 1.1e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KRH94555.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KRH94555.1 - 0.038 13.9 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like S-AdoMet_synt_C PF02773.11 KRH94556.1 - 5.8e-08 32.5 1.6 6.3e-08 32.4 1.1 1.1 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain Peptidase_M16 PF00675.15 KRH94558.1 - 5.4e-22 78.1 0.1 5.6e-21 74.8 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KRH94558.1 - 0.00096 18.8 1.7 0.036 13.7 0.3 3.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain Sipho_Gp157 PF05565.6 KRH94561.1 - 0.007 15.9 1.1 0.0082 15.7 0.8 1.0 1 0 0 1 1 1 1 Siphovirus Gp157 Med9 PF07544.8 KRH94561.1 - 0.016 14.8 1.3 0.031 14.0 0.9 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Chibby PF14645.1 KRH94561.1 - 0.017 14.9 0.6 0.02 14.7 0.4 1.2 1 0 0 1 1 1 0 Chibby family DUF972 PF06156.8 KRH94561.1 - 0.031 14.6 0.2 0.034 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SWIRM PF04433.12 KRH94561.1 - 0.033 14.2 0.4 0.035 14.2 0.3 1.1 1 0 0 1 1 1 0 SWIRM domain TSC22 PF01166.13 KRH94561.1 - 0.073 13.0 0.8 0.11 12.4 0.5 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DivIVA PF05103.8 KRH94561.1 - 0.08 13.0 2.0 0.09 12.8 1.4 1.1 1 0 0 1 1 1 0 DivIVA protein ComC PF03047.9 KRH94561.1 - 7.2 6.1 8.0 3.5 7.1 1.9 2.1 1 1 1 2 2 2 0 COMC family Pentapeptide_4 PF13599.1 KRH94562.1 - 4.5e-08 32.7 15.1 0.048 13.4 2.1 4.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) DUF2111 PF09884.4 KRH94562.1 - 0.12 12.2 1.4 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2111) DUF4100 PF13352.1 KRH94562.1 - 0.21 11.0 5.7 1 8.7 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4100) Pentapeptide_3 PF13576.1 KRH94562.1 - 0.67 9.8 27.5 7.4 6.5 4.9 5.2 2 2 1 3 3 3 0 Pentapeptide repeats (9 copies) UL11 PF11094.3 KRH94562.1 - 4.3 7.2 14.1 19 5.1 0.1 6.1 6 3 2 8 8 8 0 Membrane-associated tegument protein PEP-utilisers_N PF05524.8 KRH94564.1 - 0.25 11.1 6.2 2.1 8.1 3.6 3.0 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal S-AdoMet_synt_C PF02773.11 KRH94565.1 - 0.19 11.4 0.1 12 5.6 0.1 2.5 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain DnaJ PF00226.26 KRH94566.1 - 0.00028 20.5 0.3 0.00037 20.1 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain C1_1 PF00130.17 KRH94566.1 - 0.051 13.3 0.4 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KRH94566.1 - 0.45 10.2 3.2 0.45 10.2 1.4 1.6 2 0 0 2 2 2 0 PHD-finger DUF1426 PF07234.6 KRH94567.1 - 0.003 17.2 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1426) Herpes_LMP1 PF05297.6 KRH94567.1 - 0.0031 16.5 0.2 0.0034 16.3 0.2 1.0 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) Amnionless PF14828.1 KRH94567.1 - 0.013 14.0 0.0 0.015 13.8 0.0 1.0 1 0 0 1 1 1 0 Amnionless HemY_N PF07219.8 KRH94567.1 - 0.022 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Tenui_PVC2 PF06656.6 KRH94567.1 - 0.047 11.4 0.3 0.042 11.6 0.2 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Tetraspannin PF00335.15 KRH94567.1 - 0.047 12.9 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4579 PF15158.1 KRH94567.1 - 0.096 12.1 3.5 0.13 11.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) Pex24p PF06398.6 KRH94567.1 - 0.1 11.3 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PTS_EIIC_2 PF13303.1 KRH94567.1 - 0.32 9.8 4.5 0.4 9.5 3.1 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC OAD_gamma PF04277.8 KRH94567.1 - 3.7 7.9 5.9 13 6.2 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RVT_1 PF00078.22 KRH94572.1 - 9.5e-07 28.3 0.1 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH94572.1 - 0.072 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase thumb domain Meleagrin PF08189.6 KRH94574.1 - 0.14 11.6 0.1 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Meleagrin/Cygnin family Homeobox_KN PF05920.6 KRH94576.1 - 2.4e-17 62.3 0.9 6.4e-17 60.9 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KRH94576.1 - 6.3e-07 28.9 0.6 2e-06 27.3 0.4 1.9 1 0 0 1 1 1 1 Homeobox domain RNA_pol_Rpb1_5 PF04998.12 KRH94576.1 - 0.11 11.7 0.3 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 RVT_1 PF00078.22 KRH94578.1 - 1.2e-19 70.4 0.2 2.1e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH94580.1 - 6.9e-19 68.1 0.1 8.4e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 KRH94580.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2493 PF10686.4 KRH94580.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) Sec10 PF07393.6 KRH94580.1 - 0.079 11.1 0.1 0.082 11.0 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 ALIX_LYPXL_bnd PF13949.1 KRH94580.1 - 0.13 11.1 0.2 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PspC PF04024.7 KRH94582.1 - 0.12 11.8 0.2 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 PspC domain DUF4023 PF13215.1 KRH94583.1 - 0.14 11.9 0.6 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Retrotrans_gag PF03732.12 KRH94584.1 - 0.019 15.0 0.2 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 KRH94585.1 - 6.4e-24 84.5 0.4 1.2e-23 83.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH94585.1 - 4.1e-05 23.0 0.0 9.3e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain Cript PF10235.4 KRH94586.1 - 0.052 13.8 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Sec23_helical PF04815.10 KRH94587.1 - 0.069 12.5 0.2 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Aegerolysin PF06355.8 KRH94588.1 - 0.088 12.6 0.9 0.088 12.6 0.6 1.0 1 0 0 1 1 1 0 Aegerolysin HipA_N PF07805.7 KRH94588.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 HipA-like N-terminal domain RepL PF05732.6 KRH94589.1 - 0.0029 16.8 0.9 0.0038 16.4 0.7 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Cullin_Nedd8 PF10557.4 KRH94590.1 - 0.05 13.4 0.6 0.19 11.5 0.2 1.9 2 0 0 2 2 2 0 Cullin protein neddylation domain DUF2481 PF10654.4 KRH94590.1 - 0.28 10.8 3.3 0.38 10.4 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2481) Metallophos PF00149.23 KRH94592.1 - 5.7e-41 140.1 0.1 7.4e-41 139.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 KRH94593.1 - 4.7e-06 26.2 0.0 0.09 12.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Kelch_6 PF13964.1 KRH94593.1 - 0.014 15.5 0.1 0.3 11.3 0.0 3.1 3 0 0 3 3 3 0 Kelch motif PQQ_2 PF13360.1 KRH94593.1 - 0.12 11.8 0.0 0.71 9.2 0.0 2.3 3 1 0 3 3 3 0 PQQ-like domain YpzG PF14139.1 KRH94594.1 - 1.8 8.5 4.6 15 5.6 0.3 2.9 3 0 0 3 3 3 0 YpzG-like protein ORMDL PF04061.9 KRH94595.1 - 1.8e-28 98.7 7.2 2.1e-28 98.5 5.0 1.0 1 0 0 1 1 1 1 ORMDL family MitMem_reg PF13012.1 KRH94596.1 - 0.002 18.2 4.2 0.003 17.6 2.9 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Baculo_p24 PF05073.7 KRH94597.1 - 0.54 9.8 6.4 0.9 9.0 4.4 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein IncA PF04156.9 KRH94597.1 - 3.8 7.0 12.1 2.2 7.8 0.2 2.1 1 1 1 2 2 2 0 IncA protein HhH-GPD PF00730.20 KRH94601.1 - 3.4e-14 53.0 0.0 4.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.4 KRH94601.1 - 0.087 13.0 6.9 0.19 11.9 4.8 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III SBBP PF06739.6 KRH94602.1 - 0.34 10.7 2.9 39 4.1 0.1 3.4 3 0 0 3 3 3 0 Beta-propeller repeat LptE PF04390.7 KRH94602.1 - 1.1 8.9 6.4 5.8 6.6 4.5 2.2 1 1 0 1 1 1 0 Lipopolysaccharide-assembly TBCA PF02970.11 KRH94603.1 - 0.0015 18.5 9.4 0.002 18.1 6.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spectrin PF00435.16 KRH94603.1 - 0.011 16.0 8.8 0.37 11.0 1.0 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF1515 PF07439.6 KRH94603.1 - 0.014 15.2 0.8 0.017 14.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Val_tRNA-synt_C PF10458.4 KRH94603.1 - 0.02 14.9 5.3 0.35 10.9 0.3 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Prefoldin_2 PF01920.15 KRH94603.1 - 0.022 14.5 14.5 0.05 13.3 2.9 2.1 1 1 1 2 2 2 0 Prefoldin subunit Tctex-1 PF03645.8 KRH94603.1 - 0.036 13.8 1.8 0.036 13.8 1.3 1.8 1 1 1 2 2 2 0 Tctex-1 family Mnd1 PF03962.10 KRH94603.1 - 0.062 12.9 9.4 0.069 12.8 6.5 1.1 1 0 0 1 1 1 0 Mnd1 family FH2 PF02181.18 KRH94603.1 - 0.078 11.8 4.8 0.097 11.5 3.3 1.0 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF4559 PF15112.1 KRH94603.1 - 0.092 11.8 6.0 0.097 11.8 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DltD_M PF04918.7 KRH94603.1 - 0.1 12.7 2.6 0.13 12.4 1.8 1.2 1 0 0 1 1 1 0 DltD central region VirDNA-topo-I_N PF09266.5 KRH94603.1 - 0.12 12.3 3.9 1.8 8.5 0.3 2.5 2 1 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal pRN1_helical PF13010.1 KRH94603.1 - 0.15 11.6 5.1 0.17 11.5 3.5 1.1 1 0 0 1 1 1 0 Primase helical domain DUF1647 PF07801.6 KRH94603.1 - 0.16 11.4 1.2 0.21 11.0 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1647) TPR_7 PF13176.1 KRH94603.1 - 0.17 11.7 1.2 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.1 KRH94603.1 - 0.17 12.0 0.3 0.17 12.0 0.2 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Bap31 PF05529.7 KRH94603.1 - 0.18 11.2 9.8 0.97 8.8 6.8 1.8 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4284 PF14112.1 KRH94603.1 - 0.23 11.9 2.8 0.26 11.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) Mit_KHE1 PF10173.4 KRH94603.1 - 0.23 11.2 3.3 0.28 11.0 2.3 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SDP_N PF12278.3 KRH94603.1 - 0.32 10.6 4.2 0.39 10.3 2.9 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Sigma54_DBD PF04552.8 KRH94603.1 - 0.35 10.3 4.0 0.41 10.1 0.6 1.9 1 1 1 2 2 2 0 Sigma-54, DNA binding domain XisI PF08869.6 KRH94603.1 - 0.36 10.9 6.8 1.1 9.3 4.4 1.7 1 1 1 2 2 2 0 XisI protein DUF1664 PF07889.7 KRH94603.1 - 0.37 10.5 4.3 0.54 10.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ACCA PF03255.9 KRH94603.1 - 0.43 10.1 4.1 0.65 9.5 2.8 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2087 PF09860.4 KRH94603.1 - 0.43 10.3 3.8 0.84 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) DNApol3-delta_C PF09115.5 KRH94603.1 - 0.48 10.4 3.9 0.69 9.9 2.7 1.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Lge1 PF11488.3 KRH94603.1 - 0.7 10.1 6.8 1.7 8.8 0.4 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF3810 PF12725.2 KRH94603.1 - 0.86 8.4 4.4 0.97 8.2 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tropomyosin_1 PF12718.2 KRH94603.1 - 0.99 9.2 11.5 4.8 7.0 3.3 2.0 1 1 1 2 2 2 0 Tropomyosin like Spc24 PF08286.6 KRH94603.1 - 1.4 8.6 8.5 3.7 7.2 1.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tho2 PF11262.3 KRH94603.1 - 1.8 7.5 8.0 2 7.3 5.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Mt_ATP-synt_D PF05873.7 KRH94603.1 - 1.9 8.1 6.4 3.3 7.3 4.5 1.6 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) APG6 PF04111.7 KRH94603.1 - 2.1 7.2 10.1 2.4 7.1 7.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 KRH94603.1 - 2.5 6.4 10.3 2.8 6.2 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KRH94603.1 - 2.5 7.6 7.6 3.4 7.2 5.3 1.3 1 0 0 1 1 1 0 IncA protein TPX2 PF06886.6 KRH94603.1 - 3.4 7.7 8.9 4.1 7.5 1.9 2.1 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) TcdB_N PF12918.2 KRH94603.1 - 3.6 7.7 9.4 0.71 9.9 0.9 2.5 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain SlyX PF04102.7 KRH94603.1 - 5.5 7.4 7.6 2.7 8.4 1.6 2.2 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 KRH94603.1 - 5.7 6.8 12.5 4.4 7.1 1.2 2.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DRMBL PF07522.9 KRH94605.1 - 9.3e-21 73.9 0.6 9.3e-21 73.9 0.4 2.4 2 1 1 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KRH94605.1 - 1.7e-10 40.7 0.3 5.2e-10 39.1 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KRH94605.1 - 8.4e-06 25.5 0.1 2.4e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CoaE PF01121.15 KRH94607.1 - 8.5e-24 83.9 0.0 1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KRH94607.1 - 6.8e-10 39.3 1.1 1.4e-09 38.3 0.8 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH94607.1 - 8.4e-10 39.5 0.2 4e-09 37.3 0.2 1.9 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KRH94607.1 - 0.012 15.7 0.9 0.5 10.5 0.6 2.3 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 KRH94607.1 - 0.018 14.9 0.7 0.041 13.7 0.5 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_33 PF13671.1 KRH94607.1 - 0.02 14.7 0.0 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KRH94607.1 - 0.038 14.3 1.2 0.059 13.6 0.8 1.6 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 KRH94607.1 - 0.054 13.3 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_21 PF13304.1 KRH94607.1 - 0.49 10.2 6.2 0.84 9.5 4.3 1.4 1 1 0 1 1 1 0 AAA domain DUF4064 PF13273.1 KRH94608.1 - 5.2 7.2 8.0 0.21 11.7 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Ytp1 PF10355.4 KRH94611.1 - 0.036 13.2 0.0 0.036 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) RVT_1 PF00078.22 KRH94615.1 - 0.001 18.4 0.1 0.0026 17.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Borrelia_orfX PF04160.7 KRH94616.1 - 0.02 14.7 0.4 0.023 14.4 0.3 1.1 1 0 0 1 1 1 0 Orf-X protein UxuA PF03786.8 KRH94616.1 - 0.031 12.8 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) Glyco_transf_6 PF03414.8 KRH94617.1 - 0.097 11.1 0.0 0.097 11.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 Ribosomal_S6e PF01092.14 KRH94619.1 - 3.7e-34 117.0 0.2 6.3e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e RhoGAP PF00620.22 KRH94620.1 - 3e-19 69.1 0.3 5.1e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain PseudoU_synth_2 PF00849.17 KRH94621.1 - 1.9e-30 105.8 0.1 2.9e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KRH94621.1 - 0.018 14.4 1.9 0.019 14.3 0.0 2.1 3 0 0 3 3 3 0 S4 domain Acyl_CoA_thio PF02551.10 KRH94621.1 - 0.13 11.8 0.3 0.49 10.0 0.1 1.9 2 0 0 2 2 2 0 Acyl-CoA thioesterase POT1 PF02765.12 KRH94622.1 - 0.00015 21.6 3.0 0.00045 20.1 2.1 2.0 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 KRH94622.1 - 0.00029 20.6 0.2 1.2 9.0 0.0 3.2 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF3256 PF11644.3 KRH94622.1 - 0.0085 15.6 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3256) DUF3324 PF11797.3 KRH94622.1 - 0.065 12.9 3.0 0.13 11.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) DUF1410 PF07198.6 KRH94622.1 - 1.3 9.3 13.4 5.4 7.4 0.3 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1410) Vps16_C PF04840.7 KRH94623.1 - 1.6e-06 27.3 3.1 4.6e-06 25.8 2.1 1.8 1 1 0 1 1 1 1 Vps16, C-terminal region Ham1p_like PF01725.11 KRH94624.1 - 1.1e-24 86.8 0.0 1.3e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family iPGM_N PF06415.8 KRH94625.1 - 1.5e-27 96.3 1.1 2.2e-27 95.8 0.7 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KRH94625.1 - 1.9e-11 43.8 0.1 4.8e-11 42.5 0.1 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily Chitin_synth_1 PF01644.12 KRH94625.1 - 0.059 13.1 0.1 0.2 11.4 0.0 1.8 2 1 0 2 2 2 0 Chitin synthase LAGLIDADG_1 PF00961.14 KRH94627.1 - 1.2 9.7 6.6 2.2 8.9 0.7 2.2 1 1 1 2 2 2 0 LAGLIDADG endonuclease Imm-NTF2-2 PF15631.1 KRH94631.1 - 0.032 14.1 0.2 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein FrpC PF06901.7 KRH94631.1 - 0.042 13.3 0.1 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Lipoprotein_18 PF06804.6 KRH94631.1 - 0.053 12.2 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein ABC_tran PF00005.22 KRH94634.1 - 9.5e-30 103.6 1.5 3.8e-15 56.3 0.0 3.4 2 1 1 3 3 3 3 ABC transporter AAA_21 PF13304.1 KRH94634.1 - 8.2e-10 39.1 23.6 0.0064 16.4 0.2 4.7 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 KRH94634.1 - 8.9e-08 31.6 11.0 0.0067 15.6 0.1 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 KRH94634.1 - 1.5e-07 30.8 3.8 1.5e-07 30.8 2.6 3.5 4 0 0 4 4 3 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 KRH94634.1 - 3.6e-07 29.4 3.2 3.6e-07 29.4 2.2 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 KRH94634.1 - 7.7e-07 28.4 14.7 0.027 13.5 0.0 3.6 3 1 0 3 3 3 3 AAA ATPase domain Fer4_6 PF12837.2 KRH94634.1 - 1.3e-06 27.9 11.7 7.8e-06 25.5 1.8 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 KRH94634.1 - 2.3e-06 27.8 0.2 0.037 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KRH94634.1 - 3.3e-06 26.5 0.1 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain VirE PF05272.6 KRH94634.1 - 5e-06 26.1 1.0 0.093 12.1 0.2 3.0 2 1 0 2 2 2 2 Virulence-associated protein E DUF258 PF03193.11 KRH94634.1 - 2.4e-05 23.6 2.7 0.08 12.1 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function, DUF258 NACHT PF05729.7 KRH94634.1 - 2.9e-05 23.7 0.6 0.095 12.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KRH94634.1 - 8.2e-05 22.6 0.0 0.071 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KRH94634.1 - 8.7e-05 21.5 1.0 0.034 13.0 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.1 KRH94634.1 - 0.00014 22.7 2.9 0.0077 17.0 0.1 2.9 2 2 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KRH94634.1 - 0.00018 21.3 11.8 0.00045 20.0 8.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA PF00004.24 KRH94634.1 - 0.00034 20.8 0.1 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 KRH94634.1 - 0.00035 20.8 11.4 0.0011 19.3 0.9 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain RNA_helicase PF00910.17 KRH94634.1 - 0.0006 19.9 0.4 1.9 8.7 0.0 2.9 2 1 0 2 2 2 2 RNA helicase Fer4_2 PF12797.2 KRH94634.1 - 0.00068 19.4 11.5 0.0028 17.4 1.4 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 KRH94634.1 - 0.00097 19.4 10.4 0.0048 17.1 0.1 3.3 3 1 1 4 4 2 1 AAA domain Fer4_16 PF13484.1 KRH94634.1 - 0.0015 19.2 0.1 0.0015 19.2 0.1 2.8 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KRH94634.1 - 0.0027 17.4 1.6 0.0027 17.4 1.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_5 PF07728.9 KRH94634.1 - 0.0031 17.2 0.7 0.63 9.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KRH94634.1 - 0.0038 16.7 0.7 2.2 7.6 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 KRH94634.1 - 0.0039 16.8 0.0 0.76 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 KRH94634.1 - 0.0078 16.4 14.5 0.024 14.8 10.0 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 KRH94634.1 - 0.0099 16.3 1.0 7.1 7.1 0.0 3.0 2 1 0 2 2 2 0 Miro-like protein Fer4_4 PF12800.2 KRH94634.1 - 0.015 15.5 2.4 0.015 15.5 1.7 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_14 PF13173.1 KRH94634.1 - 0.02 14.8 5.2 3 7.7 0.1 3.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KRH94634.1 - 0.023 14.6 0.1 8.8 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KRH94634.1 - 0.024 14.6 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 KRH94634.1 - 0.03 14.8 3.1 0.03 14.8 2.1 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0079 PF02367.12 KRH94634.1 - 0.031 13.9 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KRH94634.1 - 0.033 14.0 0.0 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KRH94634.1 - 0.039 13.4 1.8 0.56 9.6 0.2 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.7 KRH94634.1 - 0.042 12.9 0.2 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus PRK PF00485.13 KRH94634.1 - 0.043 13.3 0.2 3.3 7.2 0.0 2.9 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 KRH94634.1 - 0.049 13.3 1.6 5.7 6.6 0.0 3.2 2 1 1 3 3 3 0 NTPase AAA_10 PF12846.2 KRH94634.1 - 0.062 12.7 2.0 6.1 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 KRH94634.1 - 0.093 12.6 0.0 18 5.3 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KRH94634.1 - 0.16 11.7 4.7 0.9 9.2 0.2 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_8 PF13183.1 KRH94634.1 - 0.24 11.4 11.5 0.6 10.1 8.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_23 PF13476.1 KRH94634.1 - 0.43 10.8 26.6 0.092 13.0 4.7 4.0 1 1 1 2 2 2 0 AAA domain Fer4_17 PF13534.1 KRH94634.1 - 1.1 9.6 11.7 24 5.3 8.4 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 KRH94634.1 - 5.5 7.4 11.0 0.46 10.9 2.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L28e PF01778.12 KRH94635.1 - 4.8e-22 78.5 0.1 1.1e-21 77.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family AAA_12 PF13087.1 KRH94636.1 - 6.6e-60 201.9 2.5 2.4e-59 200.0 1.7 2.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KRH94636.1 - 2.2e-55 187.8 0.7 8.1e-55 185.9 0.5 2.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KRH94636.1 - 6.9e-10 38.8 0.0 3.6e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH94636.1 - 9.8e-10 38.0 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KRH94636.1 - 0.0013 18.8 0.0 0.01 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain VTC PF09359.5 KRH94638.1 - 8.1e-58 195.6 36.0 6.7e-32 110.6 8.6 4.4 3 1 1 4 4 4 2 VTC domain DUF202 PF02656.10 KRH94638.1 - 2.3e-11 43.7 3.0 6.9e-11 42.2 2.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) LSM PF01423.17 KRH94639.1 - 1.2e-07 31.1 0.2 2.6e-07 30.1 0.1 1.5 1 1 0 1 1 1 1 LSM domain DMPK_coil PF08826.5 KRH94640.1 - 0.53 10.2 6.5 0.44 10.4 2.2 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like SGS PF05002.10 KRH94641.1 - 1.2e-07 31.4 10.9 1.5e-06 27.8 7.5 2.1 1 1 0 1 1 1 1 SGS domain tRNA-synt_His PF13393.1 KRH94641.1 - 0.088 11.8 1.9 0.1 11.6 1.3 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Peptidase_S46 PF10459.4 KRH94641.1 - 0.22 9.8 6.8 0.24 9.7 4.7 1.0 1 0 0 1 1 1 0 Peptidase S46 MitMem_reg PF13012.1 KRH94641.1 - 0.86 9.7 8.0 9.2 6.3 5.6 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Tn7_Tnp_TnsA_C PF08721.6 KRH94641.1 - 0.9 9.5 4.0 1.2 9.2 0.1 2.3 2 1 0 2 2 2 0 TnsA endonuclease C terminal DUF1053 PF06327.9 KRH94641.1 - 2 8.8 8.1 3.3 8.0 5.6 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1053) PP2C_C PF07830.8 KRH94641.1 - 2 8.5 4.5 5.5 7.1 1.1 2.2 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain NusB PF01029.13 KRH94641.1 - 3.1 7.8 6.6 4.4 7.2 4.5 1.3 1 1 0 1 1 1 0 NusB family Ndc1_Nup PF09531.5 KRH94641.1 - 3.1 6.1 5.7 3.2 6.0 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YbaJ PF10757.4 KRH94642.1 - 0.032 14.3 0.2 62 3.7 0.0 3.8 1 1 2 4 4 4 0 Biofilm formation regulator YbaJ PhaC_N PF07167.8 KRH94642.1 - 0.27 10.6 4.5 42 3.5 0.0 3.7 2 2 1 4 4 4 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Pox_polyA_pol PF03296.8 KRH94642.1 - 0.56 9.7 6.3 12 5.4 0.1 3.2 1 1 3 4 4 4 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Methyltransf_11 PF08241.7 KRH94643.1 - 3.6e-12 46.6 0.0 1.6e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KRH94643.1 - 2.5e-11 43.5 0.0 1.1e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KRH94643.1 - 3e-07 30.1 5.6 1.1e-05 25.0 3.8 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KRH94643.1 - 6.3e-06 26.5 0.4 5.6e-05 23.5 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KRH94643.1 - 1.2e-05 24.5 0.0 7.1e-05 22.0 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KRH94643.1 - 0.00062 20.3 0.0 0.0019 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KRH94643.1 - 0.0033 17.7 0.5 0.023 15.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KRH94643.1 - 0.021 13.5 0.0 0.73 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) HlyIII PF03006.15 KRH94645.1 - 2.1e-13 50.1 13.9 1.3e-06 28.0 0.4 2.1 2 0 0 2 2 2 2 Haemolysin-III related ABA_GPCR PF12430.3 KRH94645.1 - 0.082 12.0 2.9 0.17 10.9 2.0 1.5 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor LETM1 PF07766.8 KRH94646.1 - 0.0044 16.0 1.5 0.0055 15.7 1.0 1.0 1 0 0 1 1 1 1 LETM1-like protein MitMem_reg PF13012.1 KRH94646.1 - 0.011 15.8 3.0 0.015 15.4 2.1 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PilO PF04350.8 KRH94646.1 - 0.017 14.9 1.0 0.02 14.7 0.7 1.3 1 1 0 1 1 1 0 Pilus assembly protein, PilO Laminin_II PF06009.7 KRH94646.1 - 0.02 14.6 2.1 0.024 14.3 1.4 1.1 1 0 0 1 1 1 0 Laminin Domain II Borrelia_REV PF03978.8 KRH94646.1 - 0.03 14.0 5.0 0.055 13.2 3.3 1.7 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein Vac_Fusion PF02346.11 KRH94646.1 - 0.066 12.6 0.4 0.16 11.4 0.2 1.8 1 1 1 2 2 2 0 Chordopoxvirus fusion protein Phage_GP20 PF06810.6 KRH94646.1 - 0.067 12.6 4.7 0.078 12.4 3.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mod_r PF07200.8 KRH94646.1 - 0.087 12.7 2.0 0.092 12.6 1.4 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spectrin PF00435.16 KRH94646.1 - 0.094 13.0 0.3 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Spectrin repeat DASH_Duo1 PF08651.5 KRH94646.1 - 0.099 12.2 2.2 0.28 10.7 0.3 1.9 1 1 1 2 2 2 0 DASH complex subunit Duo1 AKAP7_NLS PF10469.4 KRH94646.1 - 0.11 12.1 1.6 0.12 12.0 1.1 1.0 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain V-SNARE_C PF12352.3 KRH94646.1 - 0.22 11.6 1.7 1.2 9.2 0.2 2.3 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus TBPIP PF07106.8 KRH94646.1 - 0.23 11.0 4.4 0.24 10.9 3.1 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 KRH94646.1 - 0.27 11.5 4.2 0.42 10.9 2.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2136 PF09907.4 KRH94646.1 - 0.3 11.1 1.5 0.87 9.7 1.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2136) DASH_Dam1 PF08653.5 KRH94646.1 - 0.37 10.5 3.2 1.4 8.7 0.2 2.4 1 1 1 2 2 2 0 DASH complex subunit Dam1 FlaC_arch PF05377.6 KRH94646.1 - 0.63 9.9 4.7 0.57 10.1 1.4 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Latarcin PF10279.4 KRH94646.1 - 1.8 8.8 4.9 2.6 8.3 3.3 1.4 1 1 0 1 1 1 0 Latarcin precursor Corona_S2 PF01601.11 KRH94646.1 - 4.4 5.2 5.9 4.7 5.2 4.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BAH PF01426.13 KRH94647.1 - 0.078 12.7 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 BAH domain Peptidase_C48 PF02902.14 KRH94648.1 - 4.8e-13 49.2 3.9 4.8e-13 49.2 2.7 1.7 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_25 PF13649.1 KRH94649.1 - 0.011 16.0 0.2 0.09 13.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain DUF3106 PF11304.3 KRH94650.1 - 0.2 12.1 9.0 0.039 14.3 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Pkinase PF00069.20 KRH94651.1 - 1.8e-48 164.9 0.1 1.6e-47 161.8 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH94651.1 - 8.4e-20 70.9 0.1 6.4e-16 58.1 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KRH94651.1 - 0.00026 20.8 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KRH94651.1 - 0.0077 15.8 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KRH94651.1 - 0.048 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KRH94651.1 - 0.067 12.1 0.1 1.3 7.9 0.1 2.1 1 1 0 1 1 1 0 Kinase-like tRNA-synt_1c PF00749.16 KRH94652.1 - 4.1e-71 239.2 1.0 8.2e-71 238.2 0.7 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KRH94652.1 - 6.7e-22 77.9 0.6 1.7e-21 76.6 0.4 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain CDC37_N PF03234.9 KRH94654.1 - 0.014 15.7 8.8 0.03 14.6 6.1 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4375 PF14300.1 KRH94654.1 - 0.2 11.6 7.2 2.8 7.9 1.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) WD40 PF00400.27 KRH94655.1 - 7.2e-09 35.2 0.5 0.08 12.8 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP-dep_RFKase PF01982.11 KRH94656.1 - 0.01 15.4 0.6 0.036 13.7 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF120 Myosin_head PF00063.16 KRH94657.1 - 2.1e-222 740.0 10.5 2.1e-222 740.0 7.3 4.3 3 3 1 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 KRH94657.1 - 5.7e-06 25.8 2.6 1.5e-05 24.5 1.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KRH94657.1 - 0.79 9.5 0.0 1.8 8.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain E1_dh PF00676.15 KRH94660.1 - 2.4e-65 220.2 0.0 2.8e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KRH94660.1 - 2.6e-05 23.8 0.1 4.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KRH94660.1 - 0.027 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain adh_short PF00106.20 KRH94661.1 - 1.1e-10 41.6 0.2 4.6e-05 23.3 0.1 3.1 2 1 0 2 2 2 2 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KRH94661.1 - 0.024 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KRH94661.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NTase_sub_bind PF08780.6 KRH94661.1 - 0.096 12.4 2.2 0.44 10.3 0.3 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like HypD PF01924.11 KRH94661.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase formation hypA family Y2_Tnp PF04986.8 KRH94661.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative transposase KR PF08659.5 KRH94661.1 - 0.21 11.2 0.2 0.6 9.7 0.2 1.9 1 1 0 1 1 1 0 KR domain PTR2 PF00854.16 KRH94662.1 - 1.1e-47 162.6 23.8 6.2e-36 123.9 7.4 3.2 2 1 0 2 2 2 2 POT family MFS_1 PF07690.11 KRH94662.1 - 4.8e-13 48.5 22.3 9.6e-11 40.9 9.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily AAA_17 PF13207.1 KRH94663.1 - 4.8e-09 37.0 0.1 3.8e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KRH94663.1 - 1.6e-07 31.0 0.1 2e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KRH94663.1 - 9.7e-07 28.7 0.0 2.4e-06 27.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain KTI12 PF08433.5 KRH94663.1 - 0.00011 21.5 0.0 0.0039 16.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 KRH94663.1 - 0.00013 22.2 0.0 0.00089 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KRH94663.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KRH94663.1 - 0.00038 20.3 2.2 0.0014 18.5 0.0 2.9 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 KRH94663.1 - 0.00073 19.5 0.0 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 KRH94663.1 - 0.0036 16.8 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KRH94663.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KRH94663.1 - 0.011 15.4 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KRH94663.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Chlorophyllase PF07224.6 KRH94663.1 - 0.015 14.1 0.0 0.03 13.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase NB-ARC PF00931.17 KRH94663.1 - 0.02 13.7 0.0 0.044 12.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3133 PF11331.3 KRH94663.1 - 0.022 14.3 1.0 0.05 13.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) UPF0079 PF02367.12 KRH94663.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KRH94663.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KRH94663.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 KRH94663.1 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KRH94663.1 - 0.083 13.1 0.1 0.69 10.2 0.0 2.3 2 2 0 2 2 2 0 ABC transporter NACHT PF05729.7 KRH94663.1 - 0.086 12.4 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KRH94663.1 - 0.14 12.4 7.3 0.39 11.0 4.9 2.1 1 1 0 1 1 1 0 AAA domain Trehalose_PPase PF02358.11 KRH94664.1 - 5.3e-31 107.3 0.2 2.4e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase S6PP PF05116.8 KRH94664.1 - 0.0041 16.4 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Homeobox_KN PF05920.6 KRH94664.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4615 PF15393.1 KRH94664.1 - 0.013 15.6 2.1 0.042 14.0 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Glyco_transf_20 PF00982.16 KRH94665.1 - 1.5e-18 66.5 0.2 1.8e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 RPN7 PF10602.4 KRH94666.1 - 2.1e-28 98.8 3.2 4.1e-28 97.9 2.2 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KRH94666.1 - 1.1e-09 38.4 1.9 2.8e-09 37.2 1.3 1.7 1 0 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 KRH94666.1 - 0.00021 20.8 3.5 0.00032 20.3 2.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KRH94666.1 - 0.042 13.6 0.8 0.084 12.6 0.6 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 RRM_5 PF13893.1 KRH94667.1 - 2.5e-08 33.6 0.5 0.00088 19.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH94667.1 - 1.7e-07 31.1 0.2 0.016 15.1 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KRH94667.1 - 2e-05 24.1 1.0 0.28 10.8 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KRH94667.1 - 0.0021 17.8 0.4 0.0077 16.0 0.3 1.9 1 0 0 1 1 1 1 RNA binding motif WD40 PF00400.27 KRH94668.1 - 1e-14 53.7 5.1 1.3e-08 34.3 0.7 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2703 PF10865.3 KRH94668.1 - 0.022 14.7 0.1 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) DUF3113 PF11310.3 KRH94669.1 - 0.042 13.5 4.6 0.27 10.9 1.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) T2SF PF00482.18 KRH94669.1 - 0.42 10.5 1.5 3.4 7.5 0.2 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Reo_sigmaC PF04582.7 KRH94669.1 - 6.6 5.8 21.9 0.56 9.3 2.9 3.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein S10_plectin PF03501.10 KRH94670.1 - 3e-20 71.8 0.0 3.4e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ATP-synt_10 PF05176.9 KRH94670.1 - 0.079 12.2 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 ATP10 protein Brix PF04427.13 KRH94671.1 - 4.5e-10 39.4 10.8 4.5e-10 39.4 7.5 2.1 2 1 0 2 2 2 1 Brix domain GCS PF03074.11 KRH94672.1 - 2.1e-27 96.1 1.1 2.2e-27 96.0 0.7 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Cpn60_TCP1 PF00118.19 KRH94674.1 - 0.014 14.0 0.2 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family DDE_Tnp_IS1595 PF12762.2 KRH94676.1 - 1.7e-23 83.1 0.2 2.4e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Corona_RPol_N PF06478.8 KRH94676.1 - 0.02 13.5 0.1 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus SporV_AA PF12164.3 KRH94676.1 - 0.063 13.2 0.2 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AA DUF2079 PF09852.4 KRH94677.1 - 0.0034 16.1 0.0 0.0036 16.0 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) COX7C PF02935.11 KRH94677.1 - 0.018 14.8 0.2 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc PUF PF00806.14 KRH94677.1 - 0.029 13.8 1.6 0.037 13.5 0.2 1.9 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Zn_ribbon_recom PF13408.1 KRH94677.1 - 0.041 14.1 1.8 0.076 13.2 1.2 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C4_Topoisom PF01396.14 KRH94677.1 - 0.088 12.3 3.6 0.27 10.7 2.5 1.8 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger GDI PF00996.13 KRH94679.1 - 2.9e-08 32.4 0.1 2.4e-06 26.1 0.1 2.8 3 0 0 3 3 3 3 GDP dissociation inhibitor SCA7 PF08313.7 KRH94680.1 - 3.1e-10 39.5 0.6 6.4e-10 38.5 0.4 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain Ku_PK_bind PF08785.6 KRH94680.1 - 0.028 14.3 0.9 0.042 13.7 0.7 1.2 1 0 0 1 1 1 0 Ku C terminal domain like zf-AN1 PF01428.11 KRH94680.1 - 0.048 13.5 1.0 0.048 13.5 0.7 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger SID PF11778.3 KRH94683.1 - 0.013 15.3 0.7 0.034 14.0 0.5 1.7 1 0 0 1 1 1 0 Septation initiation HD_assoc PF13286.1 KRH94683.1 - 0.044 14.0 0.6 0.075 13.3 0.1 1.7 2 0 0 2 2 2 0 Phosphohydrolase-associated domain CBFD_NFYB_HMF PF00808.18 KRH94684.1 - 1.3e-20 73.1 1.6 1.8e-20 72.7 1.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KRH94684.1 - 0.00037 20.5 0.1 0.00066 19.7 0.0 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KRH94684.1 - 0.0092 15.6 0.1 0.017 14.8 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated Ndc80_HEC PF03801.8 KRH94684.1 - 0.022 14.1 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family Pkinase PF00069.20 KRH94685.1 - 7.8e-49 166.1 2.4 9.7e-49 165.8 0.5 1.9 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH94685.1 - 3.9e-25 88.4 0.0 7.1e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH94685.1 - 2.9e-09 36.2 0.9 7e-09 35.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KRH94685.1 - 0.0024 16.9 0.3 0.014 14.4 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KRH94685.1 - 0.04 13.6 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_D PF01813.12 KRH94686.1 - 3.5e-52 176.8 3.3 4e-52 176.6 2.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D WD40 PF00400.27 KRH94687.1 - 8.6e-14 50.8 3.7 5.6e-05 22.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Imm43 PF15602.1 KRH94688.1 - 0.0067 16.4 2.4 0.0067 16.4 1.7 1.5 2 0 0 2 2 2 1 Immunity protein 43 SNARE PF05739.14 KRH94688.1 - 0.052 13.2 13.2 0.11 12.1 2.4 3.5 3 0 0 3 3 3 0 SNARE domain FliC PF12445.3 KRH94688.1 - 0.057 13.5 0.4 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 Flagellin protein Sec20 PF03908.8 KRH94688.1 - 4.7 6.9 9.4 1.9 8.2 0.8 2.7 2 1 0 2 2 2 0 Sec20 Sec1 PF00995.18 KRH94689.1 - 2.4e-10 39.6 10.5 3e-07 29.4 3.8 2.2 1 1 1 2 2 2 2 Sec1 family Cofilin_ADF PF00241.15 KRH94690.1 - 3.2e-10 39.9 0.0 4.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pneumovirus_M2 PF06436.6 KRH94690.1 - 0.07 12.3 1.1 0.11 11.7 0.7 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) TMCO5 PF14992.1 KRH94691.1 - 0.048 12.8 2.5 0.052 12.6 1.7 1.1 1 0 0 1 1 1 0 TMCO5 family LKAAEAR PF15478.1 KRH94691.1 - 0.058 13.6 2.3 0.067 13.4 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif Pox_MCEL PF03291.11 KRH94692.1 - 4.9e-51 173.5 13.7 2.5e-50 171.2 9.5 1.8 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 KRH94692.1 - 4.7e-13 48.9 0.6 6.9e-13 48.4 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KRH94692.1 - 4.5e-12 45.9 0.1 1.1e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KRH94692.1 - 1.1e-09 38.8 0.0 1.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KRH94692.1 - 1.4e-08 35.1 0.0 2.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KRH94692.1 - 8.2e-08 32.6 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KRH94692.1 - 3.8e-07 30.4 0.0 7.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KRH94692.1 - 4e-05 22.8 0.1 6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 KRH94692.1 - 0.0003 20.2 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 KRH94692.1 - 0.0005 19.2 1.1 0.00077 18.6 0.8 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 KRH94692.1 - 0.00087 18.5 0.4 0.0014 17.8 0.3 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KRH94692.1 - 0.0015 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KRH94692.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KRH94692.1 - 0.0032 16.8 0.0 0.0077 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KRH94692.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KRH94692.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 KRH94692.1 - 0.033 12.8 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.6 KRH94692.1 - 0.046 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Hema_HEFG PF02710.9 KRH94692.1 - 0.071 13.3 2.2 0.15 12.2 1.5 1.6 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein NNMT_PNMT_TEMT PF01234.12 KRH94692.1 - 0.082 11.8 0.1 0.63 8.9 0.0 2.0 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Ribosom_S12_S23 PF00164.20 KRH94693.1 - 0.057 12.8 0.0 0.061 12.7 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.20 KRH94694.1 - 3.3e-25 87.8 0.5 3.7e-25 87.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 TPR_3 PF07720.7 KRH94695.1 - 0.011 15.5 17.0 1.7 8.4 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KRH94695.1 - 0.023 14.5 24.1 0.68 9.9 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KRH94695.1 - 0.028 15.0 0.1 8 7.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KRH94695.1 - 0.2 11.5 7.4 9.6 6.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KRH94695.1 - 0.5 10.0 23.0 1.5 8.5 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KRH94695.1 - 1.1 9.2 3.6 32 4.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KRH94695.1 - 1.5 8.5 25.2 3.2 7.4 0.2 5.7 7 1 0 7 7 7 0 TPR repeat TPR_8 PF13181.1 KRH94695.1 - 1.7 8.6 20.6 13 5.8 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NifU_N PF01592.11 KRH94696.1 - 2.1e-51 173.1 0.1 2.4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Med6 PF04934.9 KRH94697.1 - 8.7e-22 77.1 2.4 1.2e-21 76.7 1.7 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DEAD PF00270.24 KRH94698.1 - 8.7e-33 113.1 0.4 3.2e-32 111.3 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH94698.1 - 1.5e-25 88.8 0.0 4.4e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KRH94698.1 - 9.2e-09 35.3 1.1 9.2e-09 35.3 0.8 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KRH94698.1 - 9e-05 21.9 2.9 0.00021 20.7 2.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 KRH94698.1 - 0.002 17.6 0.4 0.8 9.0 0.1 3.1 2 1 0 3 3 3 1 AAA-like domain RanGAP1_C PF07834.6 KRH94698.1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 RanGAP1 C-terminal domain SNF2_N PF00176.18 KRH94698.1 - 0.03 13.1 0.1 0.03 13.1 0.1 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain PhoH PF02562.11 KRH94698.1 - 0.033 13.4 0.3 0.083 12.1 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.9 KRH94698.1 - 0.038 13.7 0.6 0.15 11.7 0.0 2.2 3 0 0 3 3 3 0 Flavivirus DEAD domain AHH PF14412.1 KRH94698.1 - 0.054 13.5 1.2 10 6.1 0.2 2.8 2 1 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH AAA PF00004.24 KRH94698.1 - 0.085 13.0 0.4 0.25 11.5 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rep_fac-A_C PF08646.5 KRH94700.1 - 1.4e-39 135.1 12.5 3.7e-37 127.2 4.3 3.1 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KRH94700.1 - 1.2e-13 50.6 1.6 9.3e-10 38.2 0.0 2.9 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 KRH94700.1 - 3.4e-08 33.1 0.0 7.9e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain HypA PF01155.14 KRH94700.1 - 0.078 12.6 2.2 2.8 7.6 0.7 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family MCM PF00493.18 KRH94701.1 - 1.2e-129 431.8 2.7 1.6e-129 431.4 1.9 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KRH94701.1 - 1.2e-18 67.7 1.0 1.2e-18 67.7 0.7 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KRH94701.1 - 7.9e-12 44.7 0.5 1.1e-08 34.4 0.1 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KRH94701.1 - 7.5e-07 28.8 0.0 1.6e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH94701.1 - 3e-06 27.0 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KRH94701.1 - 0.0013 18.2 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KRH94701.1 - 0.0021 18.2 1.5 0.0095 16.1 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1546 PF07571.8 KRH94702.1 - 1.6e-17 63.3 0.0 3.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KRH94702.1 - 5.2e-17 61.5 0.4 1.6e-16 60.0 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KRH94702.1 - 0.067 13.3 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RIX1 PF08167.7 KRH94702.1 - 0.071 12.7 0.4 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis IF3_C PF00707.17 KRH94702.1 - 0.077 12.7 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain RNA_pol_Rpb1_5 PF04998.12 KRH94704.1 - 5.7e-66 222.6 14.9 4.7e-54 183.5 0.0 3.7 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KRH94704.1 - 1.2e-57 194.4 0.3 1.2e-57 194.4 0.2 2.8 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KRH94704.1 - 2e-25 89.3 0.0 2e-25 89.3 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KRH94704.1 - 5.8e-16 58.6 26.8 3.5e-11 42.9 1.1 4.3 2 1 3 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KRH94704.1 - 5.4e-15 55.0 0.1 5.4e-15 55.0 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Pkinase PF00069.20 KRH94705.1 - 6.5e-23 81.2 3.2 1e-12 47.7 0.1 3.2 2 2 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KRH94705.1 - 2.1e-10 40.1 5.4 6.7e-08 31.9 1.6 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Phasin PF05597.6 KRH94707.1 - 0.096 12.4 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SHOCT PF09851.4 KRH94707.1 - 0.31 10.5 2.7 0.51 9.8 0.3 2.5 2 0 0 2 2 2 0 Short C-terminal domain YL1_C PF08265.6 KRH94708.1 - 0.0004 19.8 0.2 0.00091 18.7 0.0 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DFF40 PF09230.5 KRH94708.1 - 0.094 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa DUF3403 PF11883.3 KRH94709.1 - 0.23 11.7 2.0 0.66 10.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3403) PHD PF00628.24 KRH94710.1 - 6.8e-07 28.8 9.1 1.6e-06 27.7 6.3 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KRH94710.1 - 0.5 10.1 8.8 0.048 13.3 2.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ELMO_CED12 PF04727.8 KRH94711.1 - 0.0014 18.1 0.5 0.0014 18.1 0.4 2.2 2 1 0 2 2 2 1 ELMO/CED-12 family MMR_HSR1_C PF08438.5 KRH94711.1 - 0.076 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 GTPase of unknown function C-terminal Synaptobrevin PF00957.16 KRH94712.1 - 0.069 12.7 1.1 0.18 11.3 0.2 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF4381 PF14316.1 KRH94712.1 - 0.19 11.7 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ribosomal_L40e PF01020.12 KRH94713.1 - 0.092 12.3 0.1 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L40e family RNase_H PF00075.19 KRH94717.1 - 0.042 14.1 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 RNase H NAC PF01849.13 KRH94717.1 - 0.054 13.0 0.4 0.088 12.3 0.3 1.3 1 0 0 1 1 1 0 NAC domain VirB3 PF05101.8 KRH94718.1 - 4.6 7.2 5.7 0.66 9.9 0.5 1.9 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein RVP_2 PF08284.6 KRH94721.1 - 2e-08 34.2 0.1 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KRH94721.1 - 5.9e-07 29.3 0.1 9.2e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH94721.1 - 1.8e-06 28.3 0.1 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94721.1 - 2.1e-05 24.2 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KRH94721.1 - 0.0041 16.6 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 KRH94721.1 - 0.0049 16.4 0.9 0.055 13.0 0.1 2.1 1 1 1 2 2 2 1 Putative peptidase (DUF1758) rve PF00665.21 KRH94722.1 - 5.1e-17 62.1 0.1 2.1e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 KRH94722.1 - 1.3e-15 57.3 0.7 5.9e-15 55.2 0.2 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ISG65-75 PF11727.3 KRH94722.1 - 0.019 14.0 0.3 0.042 12.9 0.0 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Glutaredoxin PF00462.19 KRH94722.1 - 0.13 12.2 0.3 3.5 7.6 0.1 3.0 2 0 0 2 2 2 0 Glutaredoxin Hexapep PF00132.19 KRH94723.1 - 9.5e-07 28.0 5.1 0.0091 15.4 0.9 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) zf-CCCH_2 PF14608.1 KRH94723.1 - 0.04 13.9 1.7 0.04 13.9 1.2 4.9 4 1 2 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type ACI44 PF15270.1 KRH94723.1 - 2.9 7.9 22.8 1.5 8.8 1.4 4.0 2 2 2 4 4 4 0 Metallo-carboxypeptidase inhibitor GTP_EFTU PF00009.22 KRH94727.1 - 4.6e-37 127.2 0.1 6.4e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KRH94727.1 - 4.7e-14 52.3 0.1 1.5e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KRH94727.1 - 9.3e-07 28.8 0.0 2.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KRH94727.1 - 0.053 13.3 0.7 6.3 6.5 0.0 2.8 2 1 0 3 3 3 0 Dynamin family Cpn60_TCP1 PF00118.19 KRH94728.1 - 1.7e-58 198.4 11.9 2.3e-57 194.7 8.2 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRCT PF00533.21 KRH94728.1 - 0.011 15.9 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SR-25 PF10500.4 KRH94729.1 - 0.0099 15.3 12.5 0.015 14.7 8.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Streptin-Immun PF11083.3 KRH94731.1 - 0.05 13.6 1.2 0.11 12.5 0.4 1.9 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein DUF1912 PF08930.5 KRH94732.1 - 0.046 13.8 1.1 0.13 12.3 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) IL4 PF00727.13 KRH94733.1 - 0.083 12.7 0.2 0.083 12.7 0.2 1.0 1 0 0 1 1 1 0 Interleukin 4 RGS PF00615.14 KRH94733.1 - 0.085 12.9 0.9 0.093 12.8 0.6 1.0 1 0 0 1 1 1 0 Regulator of G protein signaling domain Ribosomal_L37 PF08561.5 KRH94733.1 - 0.14 11.7 0.7 0.15 11.6 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF4446 PF14584.1 KRH94734.1 - 0.022 14.5 0.7 0.022 14.5 0.5 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4446) DivIC PF04977.10 KRH94734.1 - 0.77 9.2 9.9 1.6 8.2 2.9 2.7 1 1 1 2 2 2 0 Septum formation initiator GFP PF01353.17 KRH94735.1 - 0.0065 15.8 0.6 0.0078 15.6 0.4 1.1 1 0 0 1 1 1 1 Green fluorescent protein CytochromB561_N PF09786.4 KRH94735.1 - 0.03 12.8 4.6 0.03 12.7 2.4 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal DUF3753 PF12575.3 KRH94735.1 - 5.6 6.8 5.7 13 5.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) eIF-1a PF01176.14 KRH94736.1 - 7.7e-17 60.4 0.2 1.1e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Apc3 PF12895.2 KRH94737.1 - 0.0014 18.6 17.5 0.21 11.7 1.0 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Zn_dep_PLPC PF00882.13 KRH94737.1 - 0.01 15.5 0.3 0.027 14.1 0.2 1.7 1 0 0 1 1 1 0 Zinc dependent phospholipase C BING4CT PF08149.6 KRH94738.1 - 9.8e-26 89.0 0.0 3.4e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.9 KRH94738.1 - 4.6e-06 25.7 1.8 0.0017 17.2 0.5 2.2 1 1 1 2 2 2 2 Coatomer WD associated region AAA_23 PF13476.1 KRH94739.1 - 0.055 13.7 7.0 0.066 13.5 4.8 1.1 1 0 0 1 1 1 0 AAA domain OHA PF14418.1 KRH94739.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain PYRIN PF02758.11 KRH94739.1 - 0.071 12.8 3.3 0.13 12.0 2.3 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain PhoU PF01895.14 KRH94739.1 - 0.55 10.7 6.2 6.4 7.2 4.3 2.0 1 1 0 1 1 1 0 PhoU domain Matrilin_ccoil PF10393.4 KRH94739.1 - 0.76 9.1 3.2 2.1 7.7 0.3 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF342 PF03961.8 KRH94739.1 - 0.76 8.1 6.9 0.83 7.9 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Borealin PF10512.4 KRH94739.1 - 0.9 9.4 4.6 14 5.6 0.2 2.7 2 1 0 2 2 2 0 Cell division cycle-associated protein 8 Latarcin PF10279.4 KRH94739.1 - 3.4 7.9 10.0 4.4 7.5 6.5 1.4 1 1 0 1 1 1 0 Latarcin precursor TMF_DNA_bd PF12329.3 KRH94739.1 - 4.3 7.2 12.1 1.3 8.8 3.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pescadillo_N PF06732.6 KRH94740.1 - 1.3e-11 44.2 14.5 2.2e-11 43.5 10.1 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus SMC_N PF02463.14 KRH94741.1 - 8.2e-24 84.0 47.2 2.3e-19 69.5 32.7 4.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KRH94741.1 - 2.5e-17 62.9 0.0 1e-16 61.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 KRH94741.1 - 1.8e-07 30.5 0.1 6e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KRH94741.1 - 4e-05 23.7 76.9 4e-05 23.7 15.0 5.5 2 2 2 4 4 4 2 AAA domain PAXNEB PF05625.6 KRH94742.1 - 8e-08 31.5 2.4 0.0061 15.4 0.7 2.5 2 1 1 3 3 3 2 PAXNEB protein DUF2659 PF10858.3 KRH94743.1 - 0.063 12.6 0.7 0.07 12.5 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) Chitin_synth_2 PF03142.10 KRH94744.1 - 1.5e-199 663.7 6.0 2.2e-199 663.2 4.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KRH94744.1 - 3.4e-17 62.7 4.2 3.4e-17 62.7 2.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KRH94744.1 - 5e-17 62.4 0.0 3.2e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KRH94744.1 - 0.00016 21.3 0.1 0.33 10.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KRH94744.1 - 0.0075 15.5 0.1 0.51 9.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 KRH94744.1 - 0.049 13.4 0.1 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Asparaginase PF00710.15 KRH94747.1 - 3.7e-38 131.1 0.0 5.7e-38 130.5 0.0 1.3 1 1 0 1 1 1 1 Asparaginase DUF3961 PF13106.1 KRH94747.1 - 0.082 12.4 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) DUF2120 PF09893.4 KRH94748.1 - 0.089 12.7 2.7 0.13 12.1 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Choline_transpo PF04515.7 KRH94749.1 - 2.2e-28 99.0 40.1 2.2e-28 99.0 27.8 2.4 1 1 1 2 2 2 1 Plasma-membrane choline transporter YjgP_YjgQ PF03739.9 KRH94750.1 - 0.077 11.7 0.1 0.084 11.5 0.1 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2142 PF09913.4 KRH94750.1 - 0.21 10.2 1.3 0.23 10.0 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Ni_hydr_CYTB PF01292.15 KRH94752.1 - 0.029 13.7 0.2 0.029 13.7 0.2 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4274 PF14096.1 KRH94752.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DUF788 PF05620.6 KRH94752.1 - 0.15 11.8 1.5 0.16 11.7 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DASH_Dad2 PF08654.5 KRH94754.1 - 0.074 13.0 0.2 0.084 12.8 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 SusD-like_3 PF14322.1 KRH94754.1 - 0.14 12.2 0.2 0.14 12.2 0.1 1.0 1 0 0 1 1 1 0 Starch-binding associating with outer membrane RVT_1 PF00078.22 KRH94755.1 - 1.4e-09 37.6 0.8 2.2e-09 36.9 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med16 PF11635.3 KRH94755.1 - 0.065 11.1 0.7 0.069 11.1 0.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 rve PF00665.21 KRH94757.1 - 2.8e-13 50.0 0.0 3.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain FliG_N PF14842.1 KRH94759.1 - 0.015 15.3 0.1 0.017 15.2 0.1 1.1 1 0 0 1 1 1 0 FliG N-terminal domain DUF2414 PF10309.4 KRH94759.1 - 0.044 13.4 0.2 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) MRP-S23 PF10484.4 KRH94759.1 - 0.15 11.9 0.4 0.15 11.9 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 DUF619 PF04768.8 KRH94760.1 - 1 8.7 5.3 0.28 10.5 0.8 2.2 3 1 0 3 3 3 0 Protein of unknown function (DUF619) Asp_protease_2 PF13650.1 KRH94761.1 - 6.2e-09 36.2 0.1 9.3e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KRH94761.1 - 5.7e-08 32.5 0.2 1e-07 31.8 0.2 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KRH94761.1 - 8.3e-07 28.7 0.1 1.6e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH94761.1 - 8e-06 25.8 0.5 1.7e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH94761.1 - 3.1e-05 23.5 0.4 4.9e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 KRH94761.1 - 3.5e-05 23.4 1.5 6.3e-05 22.5 1.0 1.3 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Peptidase_A2B PF12384.3 KRH94761.1 - 0.0014 18.0 0.1 0.0022 17.3 0.1 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase TBD PF12845.2 KRH94761.1 - 0.0054 16.2 0.2 0.18 11.3 0.0 2.9 3 0 0 3 3 3 1 TBD domain RVT_1 PF00078.22 KRH94761.1 - 0.021 14.1 0.1 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) GvpO PF05800.6 KRH94761.1 - 0.11 12.4 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO DUF3121 PF11319.3 KRH94762.1 - 0.021 14.3 0.4 0.093 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) Herpes_UL52 PF03121.10 KRH94762.1 - 6.8 6.5 5.7 45 3.8 4.0 2.0 1 1 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase GCS PF03074.11 KRH94764.1 - 5.4e-05 22.4 0.0 5.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase FtsK_SpoIIIE PF01580.13 KRH94764.1 - 0.047 13.1 0.0 0.053 12.9 0.0 1.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family GCS PF03074.11 KRH94765.1 - 1.4e-19 70.4 1.9 1.6e-19 70.2 1.3 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF3310 PF11753.3 KRH94766.1 - 0.097 12.6 0.4 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) DUF1510 PF07423.6 KRH94767.1 - 5.8e-06 25.8 7.0 8.9e-06 25.2 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF1634 PF07843.6 KRH94767.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) AUX_IAA PF02309.11 KRH94767.1 - 0.62 9.7 8.5 1.1 8.9 5.9 1.4 1 0 0 1 1 1 0 AUX/IAA family SET_assoc PF11767.3 KRH94770.1 - 0.013 14.8 0.1 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF758 PF05527.6 KRH94775.1 - 0.048 13.2 0.2 0.05 13.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF758) IATP PF04568.7 KRH94775.1 - 0.15 12.0 1.7 0.2 11.7 1.2 1.1 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP RE_AlwI PF09491.5 KRH94775.1 - 0.16 10.4 2.2 0.17 10.3 1.5 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease Peptidase_M1 PF01433.15 KRH94778.1 - 1.9e-74 251.1 5.9 2.9e-72 243.9 4.1 2.3 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KRH94778.1 - 0.00072 19.5 0.2 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily tRNA-synt_2c PF01411.14 KRH94780.1 - 1.6e-138 462.3 0.3 2e-138 462.1 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) THUMP PF02926.12 KRH94781.1 - 5.4e-09 36.0 0.8 8e-09 35.5 0.1 1.6 2 0 0 2 2 2 1 THUMP domain DUF4030 PF13222.1 KRH94781.1 - 0.053 13.2 1.6 0.08 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4030) DUF2427 PF10348.4 KRH94781.1 - 0.099 12.2 0.1 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) SPRY PF00622.23 KRH94782.1 - 2.1e-15 56.8 1.2 3.7e-15 56.1 0.8 1.4 1 0 0 1 1 1 1 SPRY domain NDK PF00334.14 KRH94784.1 - 2.1e-47 160.3 0.0 2.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1803 PF08820.5 KRH94784.1 - 0.022 14.4 0.3 0.04 13.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) Homeobox PF00046.24 KRH94784.1 - 0.14 11.8 0.1 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox domain DUF1324 PF07038.6 KRH94785.1 - 0.28 11.2 3.2 0.24 11.4 0.6 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1324) zf-DHHC PF01529.15 KRH94786.1 - 1.8e-14 53.5 20.4 1.8e-14 53.5 14.1 4.3 2 2 2 4 4 4 1 DHHC palmitoyltransferase Ank_4 PF13637.1 KRH94786.1 - 2.2e-07 31.2 0.1 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KRH94786.1 - 1.7e-06 27.6 0.1 0.0001 22.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KRH94786.1 - 2.6e-05 24.4 0.0 6.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KRH94786.1 - 3.2e-05 23.4 0.0 0.0039 16.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KRH94786.1 - 0.00018 21.6 0.0 0.0043 17.2 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4359 PF14271.1 KRH94787.1 - 0.14 12.5 1.4 1.6 9.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) RVP PF00077.15 KRH94788.1 - 2.3e-09 37.0 0.0 3.1e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KRH94788.1 - 2.6e-07 31.0 0.0 3.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KRH94788.1 - 2.8e-05 23.8 0.0 7.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 KRH94788.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 KRH94788.1 - 0.018 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.7 KRH94788.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.7 1 1 1 2 2 2 0 Putative peptidase (DUF1758) RVT_1 PF00078.22 KRH94789.1 - 0.00036 19.9 0.1 0.00046 19.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KRH94791.1 - 5.2e-15 55.6 0.0 7.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF3006 PF11213.3 KRH94792.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF4553 PF15090.1 KRH94793.1 - 0.015 14.3 0.1 0.015 14.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF2207 PF09972.4 KRH94795.1 - 0.00072 18.2 2.8 0.00085 18.0 1.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Securin PF04856.8 KRH94795.1 - 0.011 15.5 1.5 0.014 15.1 1.1 1.1 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor LRRC37AB_C PF14914.1 KRH94795.1 - 0.019 14.3 1.4 0.019 14.3 1.0 1.4 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain AMA-1 PF02430.10 KRH94795.1 - 0.05 12.4 2.0 0.058 12.2 1.4 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Ycf15 PF10705.4 KRH94795.1 - 0.45 10.5 3.4 11 6.1 0.3 2.3 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative Peptidase_C48 PF02902.14 KRH94798.1 - 1.5e-17 63.9 4.7 2.8e-17 63.0 3.2 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tankyrase_bdg_C PF15327.1 KRH94800.1 - 0.0087 16.2 3.0 0.011 15.8 2.1 1.1 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain Ebola_NP PF05505.7 KRH94800.1 - 0.022 12.8 0.7 0.023 12.7 0.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Dicty_REP PF05086.7 KRH94800.1 - 0.027 12.2 2.6 0.028 12.1 1.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MCM PF00493.18 KRH94803.1 - 1.1e-109 366.2 0.1 1.8e-109 365.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KRH94803.1 - 2.6e-11 44.0 0.5 2.6e-11 44.0 0.3 3.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KRH94803.1 - 2.8e-06 26.6 0.0 9.8e-05 21.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KRH94803.1 - 0.00014 21.5 0.3 0.00075 19.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KRH94804.1 - 1.6e-18 66.7 4.6 3.4e-18 65.6 0.8 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 KRH94804.1 - 2.6e-17 62.3 0.0 5.8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KRH94804.1 - 1.5e-12 47.0 0.5 9.6e-12 44.4 0.3 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KRH94804.1 - 7.9e-07 28.6 1.5 8.5e-05 22.0 0.0 3.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KRH94804.1 - 0.00091 18.4 0.6 0.0028 16.9 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KRH94804.1 - 0.0038 16.8 0.2 0.065 12.7 0.0 2.6 2 2 0 2 2 2 1 Conserved hypothetical ATP binding protein Arf PF00025.16 KRH94804.1 - 0.0055 15.9 0.1 0.24 10.6 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 KRH94804.1 - 0.016 14.6 0.2 2.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.1 KRH94804.1 - 0.017 15.2 1.7 3.7 7.7 0.9 2.7 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KRH94804.1 - 0.025 14.4 4.3 1.6 8.5 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 KRH94804.1 - 0.053 14.0 0.4 0.44 11.0 0.0 2.5 1 1 1 2 2 2 0 Miro-like protein ABC_tran PF00005.22 KRH94804.1 - 0.057 13.7 1.2 0.18 12.1 0.7 2.1 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KRH94804.1 - 0.082 12.0 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2481 PF10654.4 KRH94804.1 - 0.19 11.4 4.9 0.4 10.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2481) AAA_18 PF13238.1 KRH94804.1 - 0.37 11.1 4.2 1.8 8.8 2.9 2.3 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KRH94804.1 - 0.78 9.1 5.3 13 5.1 0.1 3.1 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Sugar_tr PF00083.19 KRH94805.1 - 4.8e-23 81.4 42.0 2.6e-15 55.9 13.6 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KRH94805.1 - 2e-05 23.5 33.4 2e-05 23.5 23.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily UBACT PF02134.16 KRH94808.1 - 2.2e-24 84.7 0.3 1e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 KRH94808.1 - 3e-22 78.9 0.1 1.4e-13 50.8 0.0 3.8 3 1 0 3 3 3 2 ThiF family UBA_e1_thiolCys PF10585.4 KRH94808.1 - 1.7e-19 68.9 0.2 1.2e-18 66.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 KRH94808.1 - 2.8e-10 40.4 0.6 1.1e-08 35.2 0.1 3.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain ER PF01133.12 KRH94811.1 - 0.025 14.2 0.1 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Enhancer of rudimentary HTH_28 PF13518.1 KRH94814.1 - 0.0033 17.4 0.3 0.019 14.9 0.1 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_psq PF05225.11 KRH94814.1 - 0.0062 16.0 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 KRH94814.1 - 0.0071 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Nbl1_Borealin_N PF10444.4 KRH94814.1 - 0.12 11.7 0.6 0.26 10.6 0.4 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Zn_ribbon_recom PF13408.1 KRH94814.1 - 0.19 12.0 2.5 0.31 11.3 1.3 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2846 PF11008.3 KRH94815.1 - 0.1 12.4 0.3 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2846) Prefoldin_2 PF01920.15 KRH94819.1 - 0.009 15.7 0.9 0.026 14.2 0.1 1.9 2 0 0 2 2 2 1 Prefoldin subunit DUF3584 PF12128.3 KRH94820.1 - 0.00089 16.7 2.9 0.0011 16.4 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Tape_meas_lam_C PF09718.5 KRH94820.1 - 0.0014 18.4 12.8 0.033 14.1 0.4 3.7 2 1 3 5 5 5 4 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 KRH94820.1 - 0.0015 18.9 0.8 0.015 15.6 0.2 2.5 2 2 1 3 3 3 2 Bacterial protein of unknown function (DUF883) Perilipin PF03036.11 KRH94820.1 - 0.0046 15.8 3.9 0.068 11.9 1.9 2.6 1 1 1 2 2 2 1 Perilipin family MutS_III PF05192.13 KRH94820.1 - 0.012 15.4 0.9 0.022 14.5 0.6 1.4 1 0 0 1 1 1 0 MutS domain III ApoO PF09769.4 KRH94820.1 - 0.024 14.3 1.6 1.6 8.3 0.1 2.9 2 1 1 3 3 3 0 Apolipoprotein O Phasin PF05597.6 KRH94820.1 - 0.091 12.5 2.1 0.93 9.2 0.2 2.9 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3631 PF12307.3 KRH94820.1 - 0.16 11.8 1.5 0.29 11.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) DUF842 PF05811.8 KRH94820.1 - 0.17 11.3 1.6 0.41 10.1 1.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Prominin PF05478.6 KRH94820.1 - 0.2 9.1 15.3 1.3 6.4 10.5 2.0 1 1 0 1 1 1 0 Prominin DUF885 PF05960.6 KRH94820.1 - 0.28 10.3 8.5 0.37 9.8 5.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ATP-synt_B PF00430.13 KRH94820.1 - 0.33 10.7 20.0 0.15 11.8 11.6 1.9 1 1 0 2 2 2 0 ATP synthase B/B' CF(0) Mis12 PF05859.7 KRH94820.1 - 0.44 10.3 6.2 6.7 6.5 4.3 2.6 1 1 0 1 1 1 0 Mis12 protein Pex19 PF04614.7 KRH94820.1 - 0.58 9.7 8.2 0.66 9.5 4.4 2.0 2 0 0 2 2 2 0 Pex19 protein family LXG PF04740.7 KRH94820.1 - 0.79 9.4 19.6 0.6 9.8 8.4 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily UPF0160 PF03690.8 KRH94820.1 - 1.2 8.5 5.9 1.9 7.8 4.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) SF-assemblin PF06705.6 KRH94820.1 - 1.5 7.8 25.4 0.064 12.4 4.7 2.9 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF1664 PF07889.7 KRH94820.1 - 1.6 8.5 9.1 4 7.2 3.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mer2 PF09074.5 KRH94820.1 - 1.9 8.3 16.0 1.7 8.5 9.5 2.1 1 1 0 1 1 1 0 Mer2 V-SNARE PF05008.10 KRH94820.1 - 2 8.6 5.8 2.3 8.4 2.4 2.4 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DivIVA PF05103.8 KRH94820.1 - 2.9 7.9 19.1 0.83 9.7 9.6 2.5 1 1 1 2 2 2 0 DivIVA protein AIP3 PF03915.8 KRH94820.1 - 3.7 6.3 11.1 5.1 5.8 6.5 1.9 1 1 1 2 2 2 0 Actin interacting protein 3 DUF29 PF01724.11 KRH94820.1 - 4.7 7.0 9.2 8.5 6.2 3.2 2.9 1 1 1 2 2 2 0 Domain of unknown function DUF29 ApoLp-III PF07464.6 KRH94820.1 - 4.7 7.2 16.6 9.4 6.2 1.9 2.7 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Chlorosome_CsmC PF11098.3 KRH94820.1 - 5.1 6.8 17.0 3 7.5 8.7 2.7 1 1 1 2 2 2 0 Chlorosome envelope protein C V_ATPase_I PF01496.14 KRH94821.1 - 0.14 10.0 3.5 0.7 7.6 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1201 PF06716.6 KRH94822.1 - 3.8 7.4 6.7 5 7.0 4.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1201) Ribosomal_S26e PF01283.14 KRH94823.1 - 1.3e-41 141.4 7.1 1.4e-41 141.3 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Sec1 PF00995.18 KRH94824.1 - 2.4e-32 112.3 29.2 4.6e-32 111.3 20.1 1.5 1 1 0 1 1 1 1 Sec1 family QueF_N PF14819.1 KRH94824.1 - 0.85 9.7 5.8 0.15 12.1 0.8 2.0 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term ABC_tran PF00005.22 KRH94825.1 - 8e-21 74.7 4.0 1.5e-19 70.6 0.4 2.9 2 1 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.19 KRH94825.1 - 3e-17 62.4 21.8 3e-17 62.4 15.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.1 KRH94825.1 - 2.6e-10 40.7 10.5 2.6e-10 40.7 7.3 4.8 2 1 1 3 3 2 1 AAA domain AAA_17 PF13207.1 KRH94825.1 - 0.00099 19.9 0.1 0.00099 19.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KRH94825.1 - 0.0012 18.0 0.1 0.0059 15.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KRH94825.1 - 0.011 15.2 2.0 0.011 15.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KRH94825.1 - 0.018 15.2 0.1 0.087 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KRH94825.1 - 0.02 14.2 0.0 0.075 12.4 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KRH94825.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KRH94825.1 - 0.039 14.2 0.7 0.039 14.2 0.5 3.8 3 2 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KRH94825.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KRH94825.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain CDC50 PF03381.10 KRH94827.1 - 2.8e-05 23.4 0.0 2.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNA_pol_Rpb8 PF03870.10 KRH94828.1 - 0.0011 19.2 0.2 0.0025 18.0 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb8 DUF3987 PF13148.1 KRH94829.1 - 0.7 8.3 3.1 1.1 7.7 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ABC_tran PF00005.22 KRH94830.1 - 1.4e-28 99.8 16.5 2e-16 60.5 0.0 4.5 4 2 0 4 4 4 2 ABC transporter AAA_21 PF13304.1 KRH94830.1 - 1.8e-10 41.2 62.3 1.4e-06 28.5 9.6 6.0 4 2 0 4 4 4 2 AAA domain ABC_tran_2 PF12848.2 KRH94830.1 - 4.1e-09 36.1 10.2 4.1e-09 36.1 7.1 2.6 3 0 0 3 3 2 1 ABC transporter DUF258 PF03193.11 KRH94830.1 - 1.3e-06 27.6 0.3 0.00099 18.3 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KRH94830.1 - 1.1e-05 24.8 0.6 0.0047 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KRH94830.1 - 0.00013 22.0 2.1 0.49 10.5 0.0 4.8 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 KRH94830.1 - 0.0002 21.3 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KRH94830.1 - 0.00023 20.9 0.7 0.73 9.7 0.1 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KRH94830.1 - 0.00064 20.5 0.1 0.8 10.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 KRH94830.1 - 0.0011 19.2 0.0 4.5 7.4 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KRH94830.1 - 0.0014 18.2 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KRH94830.1 - 0.0041 17.0 0.0 2.8 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KRH94830.1 - 0.017 14.8 2.5 4.1 7.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Ribosomal_S19 PF00203.16 KRH94830.1 - 0.17 11.4 0.1 0.17 11.4 0.0 2.5 2 1 1 3 3 3 0 Ribosomal protein S19 AAA_25 PF13481.1 KRH94830.1 - 0.23 10.8 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ubiquitin PF00240.18 KRH94831.1 - 2.3e-15 55.7 0.2 2.7e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KRH94831.1 - 4.4e-06 26.2 0.2 4.7e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KRH94831.1 - 0.0035 17.5 0.0 0.004 17.3 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain KH_3 PF13014.1 KRH94835.1 - 1.2e-14 53.5 5.6 6.3e-08 32.1 0.1 4.2 3 0 0 3 3 3 2 KH domain KH_1 PF00013.24 KRH94835.1 - 1.5e-13 50.1 11.4 4.1e-08 32.7 0.0 4.6 4 0 0 4 4 4 3 KH domain Pentapeptide PF00805.17 KRH94835.1 - 0.0077 15.4 0.1 0.02 14.1 0.0 1.7 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Homeobox PF00046.24 KRH94838.1 - 2.1e-10 40.0 0.7 2.9e-10 39.6 0.5 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH94838.1 - 3.4e-05 23.4 0.3 5.7e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain Crystall_3 PF08964.5 KRH94838.1 - 0.02 14.5 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin VPS11_C PF12451.3 KRH94841.1 - 0.65 9.8 4.6 1.7 8.5 0.1 3.1 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal RVT_1 PF00078.22 KRH94842.1 - 1.5e-07 30.9 0.0 2.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH94843.1 - 5.2e-05 22.7 0.8 5.9e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase thumb domain FlgM PF04316.8 KRH94843.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM PUF PF00806.14 KRH94845.1 - 7.8e-42 138.4 19.5 4.1e-06 25.9 0.0 8.6 7 1 1 8 8 8 8 Pumilio-family RNA binding repeat S1 PF00575.18 KRH94846.1 - 4.6e-05 23.4 0.1 9.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 KRH94846.1 - 5.2e-05 23.2 0.1 0.0001 22.3 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Kinesin PF00225.18 KRH94847.1 - 7.2e-26 90.6 28.9 1.1e-21 76.9 0.8 4.8 3 2 1 4 4 4 3 Kinesin motor domain HHH_3 PF12836.2 KRH94847.1 - 0.00018 21.3 0.9 0.00054 19.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_22 PF13401.1 KRH94847.1 - 0.00021 21.4 2.6 0.0012 18.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain HHH PF00633.18 KRH94847.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif NDT80_PhoG PF05224.7 KRH94849.1 - 0.13 12.2 3.5 0.16 11.9 2.4 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Fzo_mitofusin PF04799.8 KRH94849.1 - 0.34 10.2 4.0 0.16 11.3 1.0 1.7 2 0 0 2 2 2 0 fzo-like conserved region DUF2951 PF11166.3 KRH94849.1 - 4.9 7.0 11.5 19 5.1 0.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2951) PTH2 PF01981.11 KRH94850.1 - 3e-26 91.3 0.3 4.9e-26 90.6 0.2 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF874 PF05917.6 KRH94850.1 - 0.0095 14.8 1.7 0.011 14.6 1.2 1.0 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) Duffy_binding PF05424.6 KRH94850.1 - 0.02 14.7 0.2 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Duffy binding domain TcdB_N PF12918.2 KRH94850.1 - 0.8 9.8 6.3 0.91 9.6 1.2 2.6 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain STE PF02200.11 KRH94851.1 - 7.8e-58 193.3 0.7 7.8e-58 193.3 0.5 1.8 2 0 0 2 2 2 1 STE like transcription factor A1_Propeptide PF07966.7 KRH94852.1 - 1 9.2 4.8 1.5 8.6 3.3 1.3 1 0 0 1 1 1 0 A1 Propeptide Choline_kinase PF01633.15 KRH94854.1 - 5.8e-43 146.9 7.1 9.3e-43 146.2 5.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KRH94854.1 - 3.5e-07 30.2 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 KRH94854.1 - 0.16 11.0 8.6 0.023 13.8 1.2 2.5 3 0 0 3 3 3 0 Ecdysteroid kinase RVT_1 PF00078.22 KRH94855.1 - 1.7e-21 76.5 0.3 3e-21 75.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 KRH94855.1 - 0.0012 18.4 0.1 0.0026 17.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RNase_H PF00075.19 KRH94855.1 - 0.0028 17.9 0.1 0.0064 16.8 0.1 1.6 1 0 0 1 1 1 1 RNase H Peptidase_C48 PF02902.14 KRH94857.1 - 1.9e-14 53.8 5.7 2.4e-14 53.4 4.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TcdB_N PF12918.2 KRH94858.1 - 0.023 14.7 2.0 0.056 13.5 0.1 2.6 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain Complex1_LYR_2 PF13233.1 KRH94858.1 - 0.034 14.6 0.4 7.7 7.0 0.0 2.4 1 1 0 2 2 2 0 Complex1_LYR-like DHC PF09626.5 KRH94858.1 - 0.13 12.9 2.1 0.56 10.8 0.2 2.2 2 0 0 2 2 2 0 Dihaem cytochrome c Ycf66_N PF07444.6 KRH94859.1 - 0.036 13.7 0.2 0.037 13.7 0.2 1.1 1 0 0 1 1 1 0 Ycf66 protein N-terminus Borrelia_REV PF03978.8 KRH94859.1 - 0.2 11.3 1.5 0.24 11.1 1.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein SID PF11778.3 KRH94860.1 - 0.04 13.8 0.2 0.046 13.6 0.2 1.0 1 0 0 1 1 1 0 Septation initiation DUF1450 PF07293.6 KRH94861.1 - 0.039 13.9 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) DUF3919 PF13057.1 KRH94861.1 - 0.055 12.9 0.5 0.084 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) priB_priC PF07445.7 KRH94865.1 - 0.0034 16.8 1.0 0.0043 16.5 0.7 1.1 1 0 0 1 1 1 1 Primosomal replication protein priB and priC DUF1878 PF08963.5 KRH94865.1 - 0.014 15.5 6.2 0.043 14.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1878) PuR_N PF09182.5 KRH94865.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Stk19 PF10494.4 KRH94865.1 - 2.4 7.4 5.6 2.4 7.4 1.3 2.0 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 Helicase_C_2 PF13307.1 KRH94866.1 - 1.7e-37 128.9 0.4 6.8e-37 126.9 0.0 2.2 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 KRH94866.1 - 6.7e-36 123.2 1.6 9.9e-36 122.7 0.3 2.0 2 0 0 2 2 2 1 DEAD_2 DUF1227 PF06777.6 KRH94866.1 - 3.4e-10 39.7 1.7 3.4e-10 39.7 1.2 3.5 4 1 0 4 4 4 1 Protein of unknown function (DUF1227) DEAD PF00270.24 KRH94866.1 - 3.8e-06 26.4 0.0 0.0061 16.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KRH94866.1 - 1.7e-05 24.7 0.1 0.0035 17.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KRH94866.1 - 0.00071 18.8 0.1 0.028 13.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein RRM_1 PF00076.17 KRH94868.1 - 4e-38 128.8 2.6 1.3e-19 69.6 0.3 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH94868.1 - 2e-29 101.3 2.0 1.5e-13 50.4 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH94868.1 - 1e-16 60.5 1.2 7.9e-11 41.6 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KRH94868.1 - 3.5e-05 23.4 0.2 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Cohesin_HEAT PF12765.2 KRH94868.1 - 0.034 14.1 1.8 0.064 13.2 1.3 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF2992 PF11208.3 KRH94871.1 - 0.12 12.2 34.9 0.18 11.7 24.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) APG6 PF04111.7 KRH94871.1 - 0.25 10.3 24.4 0.29 10.1 16.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KRH94871.1 - 0.92 7.2 21.9 1 7.1 15.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2935 PF11155.3 KRH94871.1 - 1 9.4 14.1 1.3 9.1 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Zip PF02535.17 KRH94871.1 - 3.1 6.7 11.3 4 6.3 7.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OmpH PF03938.9 KRH94871.1 - 3.3 7.6 23.6 4.6 7.1 16.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Miff PF05644.6 KRH94871.1 - 4.2 6.9 13.7 5.7 6.4 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Allexi_40kDa PF05549.6 KRH94871.1 - 4.3 6.5 16.6 4.8 6.3 11.5 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Tubulin PF00091.20 KRH94872.1 - 5.9e-72 241.9 0.1 9.9e-72 241.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KRH94872.1 - 5.3e-48 162.2 0.1 8.7e-48 161.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KRH94872.1 - 4.8e-07 29.8 0.7 8.3e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain DUF1510 PF07423.6 KRH94873.1 - 5.7 6.2 13.6 0.092 12.1 4.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RRM_1 PF00076.17 KRH94874.1 - 1.7e-06 27.5 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KRH94874.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KRH94874.1 - 0.00028 20.6 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U5_2-snRNA_bdg PF10597.4 KRH94877.1 - 4.3e-07 29.6 0.1 1.5e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Aa_trans PF01490.13 KRH94878.1 - 2.8e-31 108.4 54.5 1.6e-25 89.5 32.7 2.3 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein UNC45-central PF11701.3 KRH94878.1 - 0.043 13.4 0.8 0.12 11.9 0.3 1.8 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF4035 PF13227.1 KRH94878.1 - 0.06 12.7 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) VirionAssem_T7 PF11653.3 KRH94878.1 - 0.57 10.9 4.9 0.98 10.2 3.4 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein DUF1510 PF07423.6 KRH94878.1 - 1.6 8.0 9.7 0.13 11.5 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Aa_trans PF01490.13 KRH94879.1 - 2e-37 128.6 42.6 2.5e-37 128.3 29.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KRH94879.1 - 1.2 7.9 32.7 9.2 4.9 22.7 2.1 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family APG6 PF04111.7 KRH94881.1 - 0.00053 19.1 13.7 0.00064 18.8 9.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KRH94881.1 - 0.01 15.0 0.3 0.012 14.8 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc24 PF08286.6 KRH94881.1 - 0.021 14.5 5.0 0.021 14.5 3.5 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ACCA PF03255.9 KRH94881.1 - 0.076 12.5 6.3 0.097 12.2 0.7 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CALCOCO1 PF07888.6 KRH94881.1 - 0.085 11.1 8.4 0.087 11.0 5.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG12 PF04110.8 KRH94881.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 PhoU PF01895.14 KRH94881.1 - 0.12 12.8 0.7 0.26 11.7 0.5 1.6 1 0 0 1 1 1 0 PhoU domain Macoilin PF09726.4 KRH94881.1 - 0.23 9.7 11.6 0.095 10.9 3.3 1.9 1 1 1 2 2 2 0 Transmembrane protein TMPIT PF07851.8 KRH94881.1 - 0.26 10.3 5.0 0.31 10.0 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Nup54 PF13874.1 KRH94881.1 - 0.47 10.0 9.3 0.82 9.3 6.4 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 BRE1 PF08647.6 KRH94881.1 - 0.55 10.2 9.6 0.094 12.6 2.7 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase His_kinase PF06580.8 KRH94881.1 - 0.94 9.4 4.7 4.1 7.3 0.6 2.3 2 0 0 2 2 2 0 Histidine kinase Wbp11 PF09429.5 KRH94881.1 - 1 9.3 13.3 3.4 7.7 1.5 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 Baculo_PEP_C PF04513.7 KRH94881.1 - 1.3 8.8 6.8 3.7 7.3 2.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 KRH94881.1 - 1.4 6.6 5.8 1.6 6.4 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Erp_C PF06780.6 KRH94881.1 - 2.2 8.1 11.3 0.68 9.7 2.6 2.5 2 1 1 3 3 3 0 Erp protein C-terminus FlaC_arch PF05377.6 KRH94881.1 - 2.6 7.9 8.9 9.7 6.1 1.2 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Lzipper-MIP1 PF14389.1 KRH94881.1 - 3.9 7.6 14.8 0.093 12.8 2.8 2.8 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4527 PF15030.1 KRH94881.1 - 4.1 6.6 9.2 1.5 8.0 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) TMF_TATA_bd PF12325.3 KRH94881.1 - 4.5 7.0 13.9 6.2 6.5 6.3 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.8 KRH94881.1 - 5.7 6.7 11.8 28 4.5 4.8 2.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4404 PF14357.1 KRH94881.1 - 6.1 7.3 12.9 0.79 10.1 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Atg14 PF10186.4 KRH94881.1 - 6.7 5.5 11.6 12 4.7 8.0 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 KRH94881.1 - 7.2 6.9 7.0 5.7 7.2 0.7 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KRH94881.1 - 8.6 5.9 22.6 12 5.4 8.9 2.2 1 1 1 2 2 2 0 IncA protein AAA_23 PF13476.1 KRH94881.1 - 9 6.5 13.3 10 6.3 9.2 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 KRH94881.1 - 9.3 4.5 9.8 12 4.2 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_S24 PF00717.18 KRH94882.1 - 5.4e-09 35.5 0.1 8.1e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Pro_dh PF01619.13 KRH94883.1 - 0.052 12.5 4.6 0.089 11.7 3.2 1.3 1 0 0 1 1 1 0 Proline dehydrogenase Cor1 PF04803.7 KRH94888.1 - 0.019 14.6 1.2 0.019 14.6 0.8 2.1 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region PGAP1 PF07819.8 KRH94888.1 - 0.3 10.6 3.9 1 8.9 1.4 2.4 1 1 0 1 1 1 0 PGAP1-like protein Fringe PF02434.11 KRH94889.1 - 0.033 13.3 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Fringe-like tRNA-synt_2b PF00587.20 KRH94890.1 - 1.7e-06 27.7 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) 7TM_GPCR_Srv PF10323.4 KRH94891.1 - 0.04 13.0 3.7 0.044 12.9 2.6 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2180 PF09947.4 KRH94893.1 - 0.06 13.1 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) DUF2392 PF10288.4 KRH94894.1 - 0.069 13.4 1.4 0.14 12.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2392) Pep_deformylase PF01327.16 KRH94894.1 - 0.22 10.9 1.6 12 5.3 0.1 2.8 3 0 0 3 3 3 0 Polypeptide deformylase rve PF00665.21 KRH94896.1 - 0.056 13.5 0.4 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain rve_3 PF13683.1 KRH94896.1 - 0.075 12.5 0.3 0.18 11.3 0.1 1.8 2 0 0 2 2 2 0 Integrase core domain EIF_2_alpha PF07541.7 KRH94899.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit DUF1106 PF06523.6 KRH94900.1 - 0.022 14.5 1.8 0.17 11.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1106) WD40 PF00400.27 KRH94902.1 - 1.6e-05 24.5 0.1 0.14 12.0 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KRH94902.1 - 0.058 12.8 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain Sec6 PF06046.8 KRH94903.1 - 2e-34 118.6 13.4 2e-34 118.6 9.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF1664 PF07889.7 KRH94903.1 - 0.0025 17.6 3.5 0.012 15.3 2.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) IncA PF04156.9 KRH94903.1 - 0.7 9.4 7.7 0.61 9.6 3.3 2.5 2 0 0 2 2 2 0 IncA protein Med4 PF10018.4 KRH94903.1 - 1.3 8.3 9.1 1.7 7.9 5.2 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 vMSA PF00695.14 KRH94913.1 - 0.095 11.8 0.7 0.14 11.3 0.5 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus tRNA-synt_1 PF00133.17 KRH94914.1 - 1.8e-185 617.4 0.1 1.7e-155 518.4 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KRH94914.1 - 2.1e-24 85.9 1.3 5.5e-24 84.6 0.3 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KRH94914.1 - 6.6e-21 74.4 6.7 2.3e-06 26.5 0.9 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) RHH_1 PF01402.16 KRH94914.1 - 0.047 13.5 0.1 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family ABC_tran PF00005.22 KRH94921.1 - 6.8e-27 94.4 0.1 1.7e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KRH94921.1 - 5.4e-10 39.7 8.6 1.4e-08 35.0 1.8 3.3 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KRH94921.1 - 4.5e-09 35.8 0.2 9.7e-09 34.7 0.1 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KRH94921.1 - 0.00023 20.9 1.5 0.00036 20.3 0.1 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KRH94921.1 - 0.00029 20.9 0.2 0.00078 19.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KRH94921.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 KRH94921.1 - 0.001 19.4 3.8 0.002 18.4 2.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KRH94921.1 - 0.0014 18.1 1.5 0.021 14.2 0.5 2.5 2 1 1 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 KRH94921.1 - 0.0019 18.1 0.0 0.022 14.6 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KRH94921.1 - 0.003 17.0 0.2 0.0066 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KRH94921.1 - 0.0073 15.2 0.3 0.015 14.2 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 KRH94921.1 - 0.0097 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KRH94921.1 - 0.013 16.2 0.1 0.05 14.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KRH94921.1 - 0.021 14.2 0.1 0.054 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KRH94921.1 - 0.022 14.5 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 KRH94921.1 - 0.028 14.1 0.5 0.74 9.5 0.1 2.3 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.18 KRH94921.1 - 0.037 13.9 0.2 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KRH94921.1 - 0.066 12.9 0.2 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KRH94921.1 - 0.076 12.8 0.8 0.17 11.6 0.6 1.7 1 1 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.13 KRH94921.1 - 0.093 12.1 0.1 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 KRH94921.1 - 0.11 12.4 0.3 0.2 11.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KRH94921.1 - 0.13 11.9 0.3 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KRH94921.1 - 0.17 12.1 3.3 1.4 9.1 1.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KRH94921.1 - 0.31 10.6 0.4 0.54 9.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain PV_NSP1 PF12433.3 KRH94922.1 - 0.021 14.8 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 MFS_1 PF07690.11 KRH94923.1 - 4e-13 48.8 41.4 5.5e-07 28.6 5.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.8 KRH94923.1 - 0.0003 19.0 3.1 0.0005 18.3 2.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector IncA PF04156.9 KRH94923.1 - 7 6.1 13.0 0.14 11.6 0.1 2.9 3 1 0 3 3 3 0 IncA protein Plus-3 PF03126.13 KRH94924.1 - 7e-10 38.9 1.1 7e-10 38.9 0.8 2.7 3 1 0 3 3 3 1 Plus-3 domain UDPG_MGDP_dh_C PF03720.10 KRH94924.1 - 7 6.8 6.8 1.3 9.1 1.7 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SNF2_N PF00176.18 KRH94925.1 - 2.4e-60 203.8 1.5 2.4e-60 203.8 1.0 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KRH94925.1 - 5.1e-13 48.6 0.0 1.4e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KRH94925.1 - 7.8e-10 38.2 0.0 0.00026 20.5 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KRH94925.1 - 2.3e-07 30.4 1.1 1e-06 28.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase FadR_C PF07840.7 KRH94926.1 - 0.0061 16.1 0.3 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 FadR C-terminal domain Sterile PF03015.14 KRH94926.1 - 0.055 13.7 1.8 0.087 13.0 1.2 1.4 1 0 0 1 1 1 0 Male sterility protein Lipid_DES PF08557.5 KRH94926.1 - 0.075 12.2 0.1 0.075 12.2 0.0 2.0 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) CBFD_NFYB_HMF PF00808.18 KRH94928.1 - 1.3e-11 44.3 2.1 3.5e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KRH94928.1 - 1.6e-05 24.8 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_G2 PF11962.3 KRH94928.1 - 0.057 12.5 0.3 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain FF PF01846.14 KRH94928.1 - 0.084 12.8 2.6 0.45 10.4 0.3 2.5 2 0 0 2 2 2 0 FF domain Eaf7 PF07904.8 KRH94928.1 - 0.33 10.9 5.5 0.087 12.8 1.6 1.7 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 LMBR1 PF04791.11 KRH94928.1 - 6.3 5.2 5.2 8.2 4.8 3.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GTP_EFTU PF00009.22 KRH94929.1 - 1.5e-59 200.6 0.0 2.1e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KRH94929.1 - 6.5e-30 103.1 0.0 1.7e-29 101.7 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KRH94929.1 - 2.8e-21 75.1 0.0 6.8e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KRH94929.1 - 3.7e-13 49.1 0.0 9.4e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KRH94929.1 - 3.5e-11 43.0 0.7 8.5e-11 41.8 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TP_methylase PF00590.15 KRH94931.1 - 5.8e-17 62.1 0.0 2.6e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases AAA_2 PF07724.9 KRH94932.1 - 2.1e-42 144.9 1.0 9.5e-38 129.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KRH94932.1 - 2.1e-23 82.9 2.0 2.2e-13 50.5 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KRH94932.1 - 1.3e-17 63.8 1.1 2e-10 40.5 0.0 3.9 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KRH94932.1 - 1e-14 54.2 0.7 6.8e-14 51.5 0.5 2.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KRH94932.1 - 1.8e-10 41.1 0.2 0.0036 17.2 0.0 4.2 3 2 1 5 5 4 2 AAA ATPase domain IstB_IS21 PF01695.12 KRH94932.1 - 9.3e-10 38.2 0.0 0.0002 20.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 KRH94932.1 - 6.7e-07 28.9 0.4 0.00038 19.9 0.0 3.2 3 1 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 KRH94932.1 - 8.8e-07 29.1 1.5 0.04 14.0 0.0 4.5 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KRH94932.1 - 1.7e-06 27.9 5.8 0.019 14.8 0.0 3.8 4 0 0 4 4 3 2 AAA domain Clp_N PF02861.15 KRH94932.1 - 2.3e-06 27.4 0.3 9.6e-06 25.4 0.0 2.2 2 0 0 2 2 1 1 Clp amino terminal domain AAA_10 PF12846.2 KRH94932.1 - 2.6e-06 27.0 2.9 0.00011 21.7 0.1 3.3 2 1 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 KRH94932.1 - 6.8e-06 25.9 13.9 0.0015 18.2 0.4 5.0 3 2 1 5 5 5 2 Archaeal ATPase NACHT PF05729.7 KRH94932.1 - 9.6e-06 25.3 0.0 0.013 15.1 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_17 PF13207.1 KRH94932.1 - 1.8e-05 25.5 3.4 0.01 16.6 0.0 3.8 4 2 0 4 4 2 1 AAA domain CbiA PF01656.18 KRH94932.1 - 0.00012 21.5 0.1 0.55 9.6 0.0 3.0 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 KRH94932.1 - 0.00012 21.7 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 KRH94932.1 - 0.00016 20.8 0.2 1.1 8.4 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KRH94932.1 - 0.00022 20.4 0.1 0.45 9.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KRH94932.1 - 0.00037 20.6 0.7 0.71 10.0 0.0 3.3 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 KRH94932.1 - 0.00051 19.4 0.0 0.56 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KRH94932.1 - 0.00064 18.8 5.2 0.081 11.9 0.0 4.3 4 1 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 KRH94932.1 - 0.0012 18.2 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 KRH94932.1 - 0.0026 17.2 0.5 0.68 9.3 0.0 2.9 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KRH94932.1 - 0.0054 17.0 2.0 0.0054 17.0 1.4 4.4 3 1 0 3 3 1 1 AAA domain Torsin PF06309.6 KRH94932.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Torsin AAA_3 PF07726.6 KRH94932.1 - 0.0067 16.0 0.2 0.32 10.5 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KRH94932.1 - 0.012 15.2 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KRH94932.1 - 0.013 15.0 0.0 0.7 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KRH94932.1 - 0.036 13.7 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KRH94932.1 - 0.044 14.1 11.1 0.23 11.7 0.0 4.6 4 2 0 4 4 3 0 AAA domain AAA_28 PF13521.1 KRH94932.1 - 0.056 13.4 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KRH94932.1 - 0.056 13.3 0.0 5.6 6.8 0.0 3.2 2 0 0 2 2 2 0 AAA domain LRAT PF04970.8 KRH94932.1 - 0.15 12.0 1.3 0.57 10.1 0.0 2.7 3 0 0 3 3 1 0 Lecithin retinol acyltransferase ABC_tran PF00005.22 KRH94932.1 - 0.34 11.1 12.3 0.36 11.1 0.1 4.0 3 3 0 3 3 2 0 ABC transporter tRNA-synt_2 PF00152.15 KRH94933.1 - 3.1e-65 220.1 2.7 3.1e-65 220.1 1.8 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KRH94933.1 - 6.1e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PLC-beta_C PF08703.5 KRH94933.1 - 5.8 6.5 13.6 1.1 8.8 1.9 2.4 2 0 0 2 2 2 0 PLC-beta C terminal RNA_pol_Rpb4 PF03874.11 KRH94934.1 - 5.3e-07 29.6 9.7 7.7e-07 29.1 6.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 IFRD PF05004.8 KRH94934.1 - 0.027 13.5 1.7 0.032 13.3 1.2 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) FAM75 PF14650.1 KRH94934.1 - 0.041 13.2 1.3 0.059 12.7 0.9 1.1 1 0 0 1 1 1 0 FAM75 family TetR_C_8 PF14278.1 KRH94934.1 - 9.1 6.7 10.0 0.94 9.9 2.3 2.4 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region 2TM PF13239.1 KRH94935.1 - 6.1 6.9 17.3 0.076 13.0 1.8 3.2 2 1 1 3 3 3 0 2TM domain Sybindin PF04099.7 KRH94936.1 - 1.8e-09 37.4 1.6 3.9e-09 36.3 1.1 1.5 1 1 0 1 1 1 1 Sybindin-like family XPG_I PF00867.13 KRH94937.1 - 5.6e-12 45.5 0.0 8.6e-11 41.7 0.0 2.8 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KRH94937.1 - 2.4e-10 40.5 0.1 1.1e-09 38.3 0.0 2.3 1 1 0 1 1 1 1 XPG N-terminal domain Syntaxin-6_N PF09177.6 KRH94937.1 - 0.0023 18.2 2.6 0.0045 17.3 0.3 2.6 2 0 0 2 2 2 1 Syntaxin 6, N-terminal HTH_23 PF13384.1 KRH94938.1 - 1.1e-07 31.2 0.5 6.4e-07 28.8 0.2 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 KRH94938.1 - 1.8e-07 31.2 0.3 3.5e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.1 KRH94938.1 - 6.8e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 KRH94938.1 - 0.00035 21.2 0.6 0.0049 17.6 0.0 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 KRH94938.1 - 0.00077 18.9 1.5 0.0017 17.8 1.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KRH94938.1 - 0.0025 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 PAX PF00292.13 KRH94938.1 - 0.0052 16.4 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain Sigma54_DBD PF04552.8 KRH94938.1 - 0.011 15.1 1.2 0.025 14.0 0.1 2.0 3 0 0 3 3 3 0 Sigma-54, DNA binding domain HTH_28 PF13518.1 KRH94938.1 - 0.012 15.6 0.3 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 KRH94938.1 - 0.015 14.8 0.4 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_26 PF13443.1 KRH94938.1 - 0.015 15.5 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.11 KRH94938.1 - 0.017 14.4 0.2 0.056 12.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1732 PF08340.6 KRH94938.1 - 0.026 14.3 2.0 0.16 11.7 1.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Sigma70_ECF PF07638.6 KRH94938.1 - 0.043 13.4 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 ECF sigma factor HTH_Tnp_ISL3 PF13542.1 KRH94938.1 - 0.14 11.3 0.4 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PMM PF03332.8 KRH94940.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase GHL12 PF14882.1 KRH94940.1 - 0.15 12.2 0.4 0.55 10.3 0.0 2.0 2 1 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 PG_binding_1 PF01471.13 KRH94943.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF1430 PF07242.6 KRH94946.1 - 0.0067 16.4 0.5 0.0094 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) RNA_pol_Rpb1_1 PF04997.7 KRH94948.1 - 3.2e-95 319.2 3.3 3.2e-95 319.2 2.3 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KRH94948.1 - 2.4e-62 209.7 0.1 2.4e-62 209.7 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KRH94948.1 - 2.5e-44 150.7 0.3 6.1e-44 149.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KRH94948.1 - 4.2e-06 26.4 21.8 0.00023 20.8 0.3 3.9 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 4 Mucin PF01456.12 KRH94948.1 - 1.7 8.4 13.6 0.21 11.3 5.8 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L36e PF01158.13 KRH94949.1 - 8.5e-17 60.9 4.3 9.8e-17 60.7 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Aminotran_1_2 PF00155.16 KRH94950.1 - 2.4e-06 26.7 2.2 0.023 13.6 0.0 4.8 5 0 0 5 5 5 2 Aminotransferase class I and II SDA1 PF05285.7 KRH94950.1 - 4.7 6.4 43.2 0.037 13.3 0.1 3.3 2 1 1 3 3 3 0 SDA1 GATA PF00320.22 KRH94951.1 - 4.3e-11 41.9 4.7 4.3e-11 41.9 3.3 2.6 2 1 0 3 3 3 1 GATA zinc finger DZR PF12773.2 KRH94951.1 - 0.0058 16.4 11.8 0.15 11.9 4.1 2.6 2 1 0 2 2 2 2 Double zinc ribbon C1_1 PF00130.17 KRH94951.1 - 0.031 13.9 1.0 0.031 13.9 0.7 2.8 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Auto_anti-p27 PF06677.7 KRH94951.1 - 0.7 9.7 8.5 0.3 10.8 0.8 2.9 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_3 PF14369.1 KRH94951.1 - 2.3 8.2 11.2 2.7 8.0 0.5 2.9 2 2 0 2 2 2 0 zinc-finger Thioredoxin PF00085.15 KRH94952.1 - 4.5e-17 61.6 0.0 1.5e-13 50.2 0.1 2.9 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KRH94952.1 - 2e-12 47.2 4.7 0.00012 21.9 0.3 3.7 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KRH94952.1 - 2.3e-06 27.7 3.3 0.0015 18.7 0.6 4.2 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KRH94952.1 - 1.6e-05 24.9 1.2 0.0023 17.9 0.1 4.1 3 2 2 5 5 5 1 Thioredoxin-like AhpC-TSA PF00578.16 KRH94952.1 - 0.011 15.3 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.1 KRH94952.1 - 0.013 15.2 0.6 0.84 9.4 0.3 3.1 3 0 0 3 3 3 0 Thioredoxin domain Con-6 PF10346.4 KRH94953.1 - 0.039 13.3 0.7 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Conidiation protein 6 Sec3-PIP2_bind PF15277.1 KRH94955.1 - 0.052 13.4 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH zf-AN1 PF01428.11 KRH94956.1 - 9.9e-07 28.5 17.2 1.8e-06 27.7 11.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Pox_ser-thr_kin PF05445.6 KRH94956.1 - 0.043 12.5 2.8 0.056 12.2 2.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_S17e PF00833.13 KRH94957.1 - 5.2e-36 123.0 2.6 6.3e-36 122.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 DUF4317 PF14199.1 KRH94957.1 - 0.048 12.4 3.0 0.056 12.2 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) RicinB_lectin_2 PF14200.1 KRH94958.1 - 0.029 14.7 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Botulinum_HA-17 PF05588.6 KRH94958.1 - 0.037 13.9 1.6 0.31 10.9 0.1 2.6 1 1 2 3 3 3 0 Clostridium botulinum HA-17 protein DUF420 PF04238.7 KRH94959.1 - 0.26 11.2 1.1 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF420) GCS PF03074.11 KRH94961.1 - 2.7e-43 148.4 2.2 4.1e-31 108.3 2.0 2.9 3 0 0 3 3 3 2 Glutamate-cysteine ligase POTRA_1 PF08478.5 KRH94963.1 - 4.6 7.3 13.3 14 5.7 0.2 4.6 4 1 0 5 5 5 0 POTRA domain, FtsQ-type DUF2733 PF10813.3 KRH94965.1 - 0.00016 21.1 22.5 9.8 5.8 0.2 6.2 6 0 0 6 6 6 5 Protein of unknown function (DUF2733) Phage_DNA_bind PF02303.12 KRH94965.1 - 0.039 13.9 1.2 8.1 6.5 0.1 2.8 1 1 3 4 4 4 0 Helix-destabilising protein PRD PF00874.15 KRH94965.1 - 0.35 11.0 17.3 0.68 10.0 5.2 2.6 1 1 1 2 2 2 0 PRD domain AMP-binding_C_2 PF14535.1 KRH94965.1 - 0.41 10.7 3.0 2.2 8.3 2.1 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF916 PF06030.7 KRH94965.1 - 2.2 8.1 10.8 5.2 6.8 1.6 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF916) DuoxA PF10204.4 KRH94965.1 - 3.4 6.6 9.3 2.7 6.9 0.9 2.1 1 1 1 2 2 2 0 Dual oxidase maturation factor Ofd1_CTDD PF10637.4 KRH94965.1 - 5.6 6.0 15.1 8.5 5.4 3.7 2.3 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Adap_comp_sub PF00928.16 KRH94966.1 - 3e-13 49.4 14.6 1e-12 47.7 10.1 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family STAT6_C PF14596.1 KRH94966.1 - 0.045 13.6 0.0 0.096 12.6 0.0 1.5 2 0 0 2 2 2 0 STAT6 C-terminal DNA_pol3_a_NII PF11490.3 KRH94967.1 - 0.024 14.2 2.0 0.027 14.0 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Mut7-C PF01927.11 KRH94967.1 - 0.11 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain DNA_pol3_delta2 PF13177.1 KRH94968.1 - 7.4e-16 58.2 4.2 7.4e-16 58.2 2.9 4.4 2 2 0 2 2 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KRH94968.1 - 3.1e-14 53.3 0.0 3.1e-14 53.3 0.0 3.4 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH94968.1 - 6.9e-07 29.4 11.6 4.6e-06 26.7 1.2 4.0 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 KRH94968.1 - 0.00011 21.8 4.7 0.00019 21.1 0.1 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KRH94968.1 - 0.00035 20.6 0.1 0.00035 20.6 0.1 4.1 2 2 0 2 2 1 1 AAA ATPase domain Rep_fac_C PF08542.6 KRH94968.1 - 0.0011 18.9 0.7 0.017 15.0 0.0 3.0 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA_19 PF13245.1 KRH94968.1 - 0.0026 17.4 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KRH94968.1 - 0.0035 16.4 0.0 0.014 14.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KRH94968.1 - 0.0036 16.7 0.0 0.011 15.1 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 KRH94968.1 - 0.0043 16.9 0.1 0.0043 16.9 0.0 4.5 2 2 0 2 2 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KRH94968.1 - 0.0081 15.6 0.4 0.65 9.4 0.0 2.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 KRH94968.1 - 0.014 14.8 0.1 0.035 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KRH94968.1 - 0.023 14.3 0.0 0.18 11.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KRH94968.1 - 0.033 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KRH94968.1 - 0.037 13.1 0.0 1.2 8.2 0.0 2.2 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KRH94968.1 - 0.079 13.1 0.6 0.63 10.2 0.1 2.7 1 1 1 2 2 2 0 RNA helicase AAA_17 PF13207.1 KRH94968.1 - 0.3 11.8 0.1 0.3 11.8 0.1 4.1 1 1 1 2 2 1 0 AAA domain OmpH PF03938.9 KRH94968.1 - 4.1 7.3 77.4 1.6 8.6 19.6 3.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) V-ATPase_C PF03223.10 KRH94969.1 - 1.7e-10 40.3 22.1 5e-07 28.9 3.1 2.9 2 1 1 3 3 3 3 V-ATPase subunit C Cpn60_TCP1 PF00118.19 KRH94973.1 - 4.4e-48 164.1 14.2 1.6e-24 86.4 1.5 2.9 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Ndc1_Nup PF09531.5 KRH94973.1 - 5.8 5.1 9.9 10 4.4 6.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 KRH94977.1 - 1.9e-10 40.0 20.6 9.4e-06 24.5 6.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 KRH94977.1 - 2.9e-07 29.1 0.7 5.7e-07 28.1 0.5 1.4 1 1 0 1 1 1 1 Membrane transport protein DUF1510 PF07423.6 KRH94977.1 - 7.5e-06 25.4 13.9 1.1e-05 24.8 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KRH94977.1 - 9.6e-05 20.3 1.2 0.00013 19.8 0.8 1.1 1 0 0 1 1 1 1 Ycf1 SAPS PF04499.10 KRH94977.1 - 0.00022 20.0 0.0 0.00026 19.7 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Zip PF02535.17 KRH94977.1 - 0.0003 19.9 0.0 0.0003 19.9 0.0 2.5 3 0 0 3 3 3 1 ZIP Zinc transporter Peptidase_S49_N PF08496.5 KRH94977.1 - 0.0024 17.6 2.7 0.0043 16.8 1.9 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal IncA PF04156.9 KRH94977.1 - 0.0035 16.9 0.3 0.0035 16.9 0.2 1.9 2 0 0 2 2 1 1 IncA protein SpoIIIAH PF12685.2 KRH94977.1 - 0.0038 16.7 6.2 0.0055 16.2 4.3 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein EphA2_TM PF14575.1 KRH94977.1 - 0.019 15.3 0.0 0.019 15.3 0.0 3.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AIF_C PF14721.1 KRH94977.1 - 0.02 15.1 0.8 0.02 15.1 0.5 2.1 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spore_coat_CotO PF14153.1 KRH94977.1 - 0.034 13.5 10.1 0.047 13.1 7.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO NPR3 PF03666.8 KRH94977.1 - 0.045 12.2 6.8 0.064 11.7 4.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF-MLS PF14962.1 KRH94977.1 - 0.068 12.8 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Pex16 PF08610.5 KRH94977.1 - 0.37 9.7 3.8 1.2 8.1 2.6 1.8 1 1 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3278 PF11683.3 KRH94977.1 - 0.49 10.3 0.0 0.49 10.3 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3278) Hid1 PF12722.2 KRH94977.1 - 1.7 6.2 17.3 2.4 5.7 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NfeD PF01957.13 KRH94977.1 - 2.4 8.3 7.3 17 5.5 0.0 3.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding FAM176 PF14851.1 KRH94977.1 - 4.1 7.0 12.0 0.47 10.1 2.4 2.1 1 1 1 2 2 2 0 FAM176 family DUF2201_N PF13203.1 KRH94977.1 - 4.2 6.4 12.1 6 5.9 8.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Vpu PF00558.14 KRH94978.1 - 0.072 12.6 0.0 0.3 10.6 0.0 2.1 1 1 0 1 1 1 0 Vpu protein DUF4163 PF13739.1 KRH94978.1 - 2.3 9.0 18.6 1.4 9.6 4.7 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4163) BBS2_Mid PF14783.1 KRH94979.1 - 0.0011 18.7 0.0 0.084 12.6 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region CPSF_A PF03178.10 KRH94979.1 - 0.0023 17.0 0.2 0.0064 15.6 0.1 1.6 1 1 0 1 1 1 1 CPSF A subunit region Rpr2 PF04032.11 KRH94979.1 - 0.0093 15.8 0.2 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_28 PF00295.12 KRH94980.1 - 0.13 11.2 7.7 0.17 10.8 5.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 MSV199 PF10553.4 KRH94980.1 - 2.9 7.7 12.8 3.8 7.3 4.9 2.5 2 1 1 3 3 3 0 MSV199 domain FBA_2 PF07735.12 KRH94980.1 - 9.5 6.1 7.8 1.4e+02 2.4 4.8 2.9 2 1 0 2 2 2 0 F-box associated Haemocyan_bet_s PF14830.1 KRH94981.1 - 0.022 14.4 0.1 0.029 14.0 0.1 1.1 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Peptidase_S7 PF00949.16 KRH94981.1 - 0.025 13.9 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease C1_1 PF00130.17 KRH94983.1 - 2.4 7.9 5.7 0.29 10.8 0.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_Tnp_IS1595 PF12762.2 KRH94985.1 - 6.7e-06 26.0 0.0 7.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF2666 PF10869.3 KRH94991.1 - 0.063 13.3 0.2 0.078 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Phyto_Pns9_10 PF05878.6 KRH94991.1 - 0.078 11.9 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Ras_bdg_2 PF14847.1 KRH94991.1 - 0.085 12.7 0.2 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Ras-binding domain of Byr2 PA28_alpha PF02251.13 KRH94992.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit RVT_1 PF00078.22 KRH94993.1 - 1.8e-05 24.2 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RGS-like PF09128.6 KRH94994.1 - 0.096 12.1 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain rve_3 PF13683.1 KRH94995.1 - 1.8e-06 27.3 0.1 2.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 KRH94995.1 - 2.8e-05 24.2 0.0 4.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF1726 PF08351.6 KRH94995.1 - 0.034 13.8 0.0 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) ABC_tran PF00005.22 KRH94998.1 - 2.1e-22 79.9 0.0 3.9e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 KRH94998.1 - 2.7e-05 24.0 0.4 8.5e-05 22.3 0.1 1.9 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KRH94998.1 - 0.00011 22.3 0.0 0.00032 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KRH94998.1 - 0.0002 20.6 1.6 0.00066 18.9 1.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KRH94998.1 - 0.00026 21.0 6.9 0.00026 21.0 4.8 3.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KRH94998.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.1 KRH94998.1 - 0.0018 18.1 0.9 0.14 12.0 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.1 KRH94998.1 - 0.0026 18.1 4.1 0.0059 16.9 2.8 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KRH94998.1 - 0.0043 16.2 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_13 PF13166.1 KRH94998.1 - 0.0047 15.4 4.3 0.0054 15.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KRH94998.1 - 0.007 15.8 0.1 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 KRH94998.1 - 0.0089 15.6 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 KRH94998.1 - 0.013 15.7 0.1 0.079 13.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 KRH94998.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KRH94998.1 - 0.015 14.9 0.2 0.97 9.1 0.0 2.3 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KRH94998.1 - 0.016 14.1 0.2 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 KRH94998.1 - 0.016 16.0 0.3 0.066 14.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KRH94998.1 - 0.017 14.6 0.3 0.036 13.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 KRH94998.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KRH94998.1 - 0.019 14.4 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KRH94998.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KRH94998.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KRH94998.1 - 0.026 13.9 0.2 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KRH94998.1 - 0.045 13.9 2.0 0.75 9.9 1.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KRH94998.1 - 0.075 12.9 1.0 0.45 10.4 0.8 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KRH94998.1 - 0.08 12.4 0.1 0.23 10.9 0.1 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KRH94998.1 - 0.083 13.3 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 KRH94998.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain YIF1 PF03878.10 KRH94999.1 - 0.66 9.0 22.1 1e+02 1.9 15.3 3.0 1 1 0 1 1 1 0 YIF1 DUF2368 PF10166.4 KRH95000.1 - 0.0017 17.9 2.7 6.8 6.2 0.1 3.7 1 1 3 4 4 4 3 Uncharacterised conserved protein (DUF2368) GrpB PF04229.9 KRH95000.1 - 0.071 12.8 1.4 9.3 5.9 0.0 2.5 1 1 2 3 3 3 0 GrpB protein Cadherin_2 PF08266.7 KRH95000.1 - 8.7 5.9 17.3 54 3.4 0.1 5.9 1 1 6 7 7 7 0 Cadherin-like DUF4378 PF14309.1 KRH95001.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Pex24p PF06398.6 KRH95005.1 - 0.043 12.6 0.3 0.047 12.4 0.2 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Borrelia_lipo_2 PF06238.6 KRH95005.1 - 0.053 13.5 2.1 0.067 13.2 1.4 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein TPR_15 PF13429.1 KRH95005.1 - 0.086 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1989 PF09347.5 KRH95005.1 - 0.13 11.7 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1989) SAP PF02037.22 KRH95006.1 - 3.6e-05 23.1 0.0 7.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain rve PF00665.21 KRH95007.1 - 0.02 15.0 0.8 0.15 12.1 0.5 2.1 1 1 1 2 2 2 0 Integrase core domain DUF1510 PF07423.6 KRH95012.1 - 0.00041 19.7 7.0 0.00047 19.5 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 KRH95012.1 - 0.0017 17.8 2.5 0.002 17.6 1.7 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2371 PF10177.4 KRH95012.1 - 0.16 11.8 0.5 0.3 10.9 0.3 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) SID-1_RNA_chan PF13965.1 KRH95012.1 - 0.16 10.0 0.4 0.17 10.0 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.1 KRH95012.1 - 0.19 12.1 1.5 1.3 9.4 1.0 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 KRH95013.1 - 0.00016 21.1 11.1 0.00024 20.5 7.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 KRH95013.1 - 0.012 13.9 0.2 0.013 13.8 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein GPCR_chapero_1 PF11904.3 KRH95013.1 - 0.019 14.1 9.6 0.6 9.1 0.0 2.1 2 0 0 2 2 2 0 GPCR-chaperone CDC45 PF02724.9 KRH95013.1 - 0.028 12.4 2.9 0.039 12.0 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 KRH95013.1 - 0.078 11.5 4.1 0.13 10.8 2.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3362 PF11842.3 KRH95013.1 - 0.19 11.6 6.2 0.46 10.3 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) LMBR1 PF04791.11 KRH95013.1 - 0.26 9.8 3.6 0.89 8.0 1.4 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein MEF2_binding PF09047.5 KRH95013.1 - 8.6 6.0 8.1 49 3.6 0.1 3.2 3 0 0 3 3 3 0 MEF2 binding Pkinase PF00069.20 KRH95014.1 - 7.1e-24 84.3 1.0 6.9e-23 81.1 0.7 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH95014.1 - 4.4e-13 48.8 0.1 5.4e-12 45.3 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH95014.1 - 0.00055 18.9 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TcdB_N PF12918.2 KRH95015.1 - 0.0022 18.0 1.2 0.007 16.4 0.2 2.3 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain PIF1 PF05970.9 KRH95015.1 - 0.056 12.3 0.6 0.081 11.8 0.1 1.5 2 0 0 2 2 2 0 PIF1-like helicase dUTPase PF00692.14 KRH95016.1 - 2.1e-12 46.6 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase MIF4G PF02854.14 KRH95017.1 - 9e-15 54.6 8.2 9e-15 54.6 5.7 2.0 2 0 0 2 2 2 1 MIF4G domain UvdE PF03851.9 KRH95017.1 - 0.00082 18.4 0.2 0.0023 16.9 0.2 1.8 1 0 0 1 1 1 1 UV-endonuclease UvdE Cript PF10235.4 KRH95018.1 - 0.21 11.9 2.5 0.34 11.3 1.7 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Peptidase_A17 PF05380.8 KRH95019.1 - 0.054 13.3 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Pao retrotransposon peptidase SHP PF03579.8 KRH95020.1 - 0.0026 17.0 0.4 0.0031 16.8 0.3 1.2 1 0 0 1 1 1 1 Small hydrophobic protein Cytochrom_B561 PF03188.11 KRH95020.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 ATG27 PF09451.5 KRH95020.1 - 0.095 11.9 0.1 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 Lig_chan PF00060.21 KRH95020.1 - 0.12 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel Baculo_11_kDa PF06143.6 KRH95020.1 - 0.33 10.3 2.9 0.32 10.3 1.4 1.5 1 1 1 2 2 2 0 Baculovirus 11 kDa family Methyltransf_4 PF02390.12 KRH95021.1 - 2.9e-40 137.4 1.9 2.9e-39 134.1 1.3 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KRH95021.1 - 8.7e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KRH95021.1 - 0.00045 20.7 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KRH95021.1 - 0.0025 17.1 0.0 0.0049 16.2 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 KRH95021.1 - 0.0063 16.2 0.1 0.073 12.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 KRH95021.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 KRH95021.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KRH95021.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KRH95021.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22e PF01776.12 KRH95022.1 - 1.1e-24 86.5 2.3 1.5e-24 86.1 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family PBS_linker_poly PF00427.16 KRH95022.1 - 0.025 14.2 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Yippee-Mis18 PF03226.9 KRH95022.1 - 0.076 13.0 0.9 0.91 9.6 0.4 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cys_rich_KTR PF14205.1 KRH95022.1 - 0.14 11.6 1.0 0.26 10.7 0.2 1.8 1 1 1 2 2 2 0 Cysteine-rich KTR DUF1413 PF07205.6 KRH95022.1 - 0.23 11.0 2.9 0.26 10.8 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) Pkinase PF00069.20 KRH95023.1 - 1.5e-52 178.3 6.3 1.8e-52 178.0 4.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH95023.1 - 4.7e-41 140.5 1.6 5.8e-41 140.2 1.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH95023.1 - 0.00019 20.4 0.2 0.00088 18.3 0.1 1.9 1 1 0 1 1 1 1 Kinase-like LAGLIDADG_1 PF00961.14 KRH95023.1 - 0.24 11.9 13.9 0.16 12.5 4.8 2.7 2 0 0 2 2 2 0 LAGLIDADG endonuclease Cation_efflux PF01545.16 KRH95024.1 - 4.3e-61 206.4 13.5 5e-61 206.2 9.3 1.0 1 0 0 1 1 1 1 Cation efflux family AA_permease_2 PF13520.1 KRH95024.1 - 0.0064 15.0 3.7 0.0064 15.0 2.6 2.1 2 0 0 2 2 2 2 Amino acid permease DUF3278 PF11683.3 KRH95024.1 - 0.87 9.5 10.9 0.76 9.7 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) tRNA-synt_1c PF00749.16 KRH95026.1 - 8.7e-88 293.9 0.3 1.4e-87 293.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KRH95026.1 - 4.2e-14 52.5 0.1 1.2e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 KRH95026.1 - 0.0053 17.4 0.2 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 IL31 PF15209.1 KRH95026.1 - 0.39 10.3 6.6 0.13 11.8 2.2 2.0 2 0 0 2 2 2 0 Interleukin 31 DUF382 PF04037.8 KRH95027.1 - 3.5e-08 33.3 0.7 3.5e-08 33.3 0.5 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF382) HTH_26 PF13443.1 KRH95027.1 - 0.035 14.3 0.3 0.066 13.4 0.2 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 KRH95029.1 - 2.2e-07 30.3 0.0 2.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 KRH95029.1 - 1e-06 28.5 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.1 KRH95029.1 - 3.6e-06 27.0 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix TrmB PF01978.14 KRH95029.1 - 3.9e-05 23.2 0.0 0.005 16.5 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 KRH95029.1 - 6.2e-05 22.3 0.0 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_33 PF13592.1 KRH95029.1 - 6.7e-05 22.3 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 KRH95029.1 - 0.0002 20.7 0.1 0.00056 19.3 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_32 PF13565.1 KRH95029.1 - 0.00079 20.1 0.0 0.0012 19.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 KRH95029.1 - 0.0012 18.3 1.3 0.48 10.0 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain Terminase_5 PF06056.7 KRH95029.1 - 0.0099 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.1 KRH95029.1 - 0.038 13.5 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 KRH95029.1 - 0.052 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.5 KRH95029.1 - 0.056 13.0 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 KRH95029.1 - 0.095 12.7 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_7 PF02796.10 KRH95029.1 - 0.12 12.3 1.2 3.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 KRH95029.1 - 0.13 11.9 0.0 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 HTH domain Phage_AlpA PF05930.7 KRH95029.1 - 0.14 11.8 0.0 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.2 KRH95029.1 - 0.15 12.3 0.1 7.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 KRH95030.1 - 6.4e-09 35.7 0.1 9.7e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Flt3_lig PF02947.9 KRH95030.1 - 0.061 13.2 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 flt3 ligand WBS_methylT PF12589.3 KRH95034.1 - 0.42 11.1 4.6 0.58 10.6 3.2 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome T4_baseplate PF12322.3 KRH95036.1 - 0.0021 17.3 0.3 0.0022 17.2 0.2 1.0 1 0 0 1 1 1 1 T4 bacteriophage base plate protein PyrI_C PF02748.10 KRH95036.1 - 0.016 14.6 1.9 0.26 10.7 0.1 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Elf1 PF05129.8 KRH95036.1 - 0.093 12.4 0.5 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ribosomal_S27e PF01667.12 KRH95036.1 - 0.095 12.2 1.4 0.1 12.1 0.2 1.7 1 1 1 2 2 2 0 Ribosomal protein S27 DUF3909 PF13077.1 KRH95039.1 - 0.13 12.0 0.4 0.15 11.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) ABC_tran PF00005.22 KRH95043.1 - 3.9e-22 79.0 0.0 8.4e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KRH95043.1 - 2e-06 27.1 12.9 2e-06 27.1 8.9 3.0 2 1 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.1 KRH95043.1 - 1.1e-05 25.5 5.7 1.1e-05 25.5 4.0 4.0 3 2 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KRH95043.1 - 0.00023 21.3 0.7 0.0031 17.6 0.5 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KRH95043.1 - 0.00023 20.4 0.8 0.41 9.8 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KRH95043.1 - 0.00026 21.3 8.9 0.0071 16.6 6.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH95043.1 - 0.0003 21.5 0.1 0.001 19.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KRH95043.1 - 0.00043 20.3 0.2 0.00077 19.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KRH95043.1 - 0.0019 17.7 0.6 0.035 13.5 0.3 2.4 2 1 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KRH95043.1 - 0.0044 16.2 0.1 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KRH95043.1 - 0.0081 16.1 0.0 0.025 14.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KRH95043.1 - 0.0084 16.3 3.1 0.03 14.5 0.6 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KRH95043.1 - 0.01 15.2 0.6 0.035 13.5 0.2 2.1 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KRH95043.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KRH95043.1 - 0.014 15.3 0.6 0.032 14.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KRH95043.1 - 0.019 14.6 0.2 0.04 13.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KRH95043.1 - 0.02 15.1 3.6 0.03 14.6 0.9 2.5 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 KRH95043.1 - 0.022 14.4 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KRH95043.1 - 0.023 14.1 1.0 0.053 13.0 0.7 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KRH95043.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KRH95043.1 - 0.025 14.4 1.3 0.14 12.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 KRH95043.1 - 0.032 13.1 0.8 0.073 11.9 0.6 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KRH95043.1 - 0.041 13.6 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain PduV-EutP PF10662.4 KRH95043.1 - 0.041 13.3 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KRH95043.1 - 0.041 13.6 1.3 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.1 KRH95043.1 - 0.046 13.3 2.8 0.21 11.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KRH95043.1 - 0.06 13.0 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KRH95043.1 - 0.064 12.9 0.7 0.26 10.9 0.1 2.2 2 1 0 2 2 2 0 NTPase cobW PF02492.14 KRH95043.1 - 0.075 12.4 0.8 0.21 11.0 0.6 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KRH95043.1 - 0.12 11.7 0.1 0.4 10.1 0.1 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-U11-48K PF05253.7 KRH95044.1 - 0.59 9.9 3.3 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger E2R135 PF11570.3 KRH95044.1 - 4.6 7.3 6.5 5.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Enterotoxin_HS1 PF08090.6 KRH95055.1 - 0.43 10.3 2.6 0.88 9.3 1.8 1.5 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 Ni_hydr_CYTB PF01292.15 KRH95055.1 - 8.5 5.7 11.5 7.7 5.8 0.6 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 SNF2_N PF00176.18 KRH95058.1 - 3.2e-16 59.0 0.2 6.2e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KRH95058.1 - 2.8e-10 39.8 0.4 9e-09 35.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDP-OH_P_transf PF01066.16 KRH95059.1 - 2.6e-15 56.5 24.9 1.2e-13 51.1 17.2 3.2 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HA2 PF04408.18 KRH95060.1 - 2.3e-15 56.4 0.0 7.1e-15 54.8 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) DEAD PF00270.24 KRH95060.1 - 7.7e-10 38.5 0.3 1.9e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KRH95060.1 - 9.1e-09 35.0 0.2 2.2e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KRH95060.1 - 2.2e-07 30.6 0.0 5.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KRH95060.1 - 0.00031 20.8 0.0 0.00088 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KRH95060.1 - 0.0021 17.9 2.6 0.0068 16.2 0.1 2.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KRH95060.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KRH95060.1 - 0.047 13.5 2.9 0.26 11.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain DUF2084 PF09857.4 KRH95060.1 - 0.089 12.5 0.1 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2084) T2SE PF00437.15 KRH95060.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KRH95060.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KRH95060.1 - 0.16 12.2 0.2 0.16 12.2 0.1 3.7 3 2 0 4 4 4 0 AAA domain eIF2A PF08662.6 KRH95061.1 - 2.4e-29 102.4 2.5 3.3e-29 101.9 0.3 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KRH95061.1 - 0.018 13.8 0.9 0.054 12.2 0.1 2.0 1 1 1 2 2 2 0 Coatomer WD associated region EIF_2_alpha PF07541.7 KRH95064.1 - 1.2e-19 70.0 0.7 7.4e-17 61.1 0.1 2.9 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KRH95064.1 - 7.1e-08 32.4 1.2 1.4e-07 31.4 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HI0933_like PF03486.9 KRH95064.1 - 0.076 11.4 0.1 0.18 10.2 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein Med18 PF09637.5 KRH95066.1 - 0.0032 17.0 0.0 0.015 14.8 0.0 2.1 2 1 1 3 3 3 1 Med18 protein RNA_pol_Rpb2_6 PF00562.23 KRH95068.1 - 2.8e-129 431.2 0.9 4.2e-129 430.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KRH95068.1 - 7.4e-60 201.3 0.3 1.2e-59 200.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KRH95068.1 - 4.6e-41 140.3 1.0 7.8e-41 139.5 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KRH95068.1 - 6.6e-28 96.7 0.1 2e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 KRH95068.1 - 6.6e-27 93.0 0.0 1.4e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KRH95068.1 - 5e-19 67.8 0.0 1.5e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KRH95068.1 - 1.7e-16 59.8 0.1 4.5e-16 58.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-RING_2 PF13639.1 KRH95069.1 - 7.8e-13 48.0 8.5 1.3e-12 47.2 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KRH95069.1 - 3.1e-09 36.8 4.5 6.6e-09 35.7 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KRH95069.1 - 1.6e-06 28.0 8.4 2.8e-06 27.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH95069.1 - 5.5e-06 25.9 5.1 8.6e-06 25.3 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH95069.1 - 2.5e-05 23.8 7.8 5e-05 22.8 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH95069.1 - 4.2e-05 23.1 6.3 7.4e-05 22.4 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KRH95069.1 - 0.0012 18.6 4.3 0.0025 17.6 3.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KRH95069.1 - 0.059 13.3 4.7 0.13 12.2 3.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KRH95069.1 - 0.1 12.1 4.9 0.21 11.1 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain S_layer_N PF05123.7 KRH95069.1 - 2.4 7.7 6.8 0.33 10.5 0.3 2.3 3 0 0 3 3 3 0 S-layer like family, N-terminal region PHD PF00628.24 KRH95069.1 - 2.6 7.8 10.4 0.85 9.3 5.3 1.7 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KRH95069.1 - 2.6 8.0 6.0 6.4 6.7 4.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KRH95069.1 - 6.4 6.9 8.8 14 5.8 6.1 1.5 1 0 0 1 1 1 0 RING-variant domain Ribosomal_L15e PF00827.12 KRH95070.1 - 7.3e-70 234.3 2.6 1e-69 233.9 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L15 RNA_pol_L_2 PF13656.1 KRH95071.1 - 3.7e-19 67.9 0.2 4.7e-19 67.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KRH95071.1 - 0.0072 15.4 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LsmAD PF06741.8 KRH95072.1 - 1.9e-11 43.9 6.3 1.9e-11 43.9 4.3 2.6 2 1 0 2 2 2 1 LsmAD domain FtsJ PF01728.14 KRH95073.1 - 2.9e-55 187.0 0.1 5.5e-55 186.1 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KRH95073.1 - 1.5e-11 44.0 10.2 1.5e-11 44.0 7.1 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_18 PF12847.2 KRH95073.1 - 0.00052 20.5 0.1 0.7 10.4 0.0 3.5 2 1 0 2 2 2 1 Methyltransferase domain Spb1_C PF07780.7 KRH95073.1 - 0.0015 18.0 13.0 0.0015 18.0 9.0 3.2 1 1 2 3 3 3 1 Spb1 C-terminal domain Methyltrans_Mon PF14314.1 KRH95073.1 - 0.0023 15.8 0.1 0.0044 14.9 0.1 1.4 1 0 0 1 1 1 1 Virus-capping methyltransferase Methyltransf_25 PF13649.1 KRH95073.1 - 0.004 17.4 2.0 0.13 12.6 0.0 3.2 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KRH95073.1 - 0.038 13.7 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF4559 PF15112.1 KRH95074.1 - 0.61 9.2 8.6 1 8.4 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Sod_Fe_C PF02777.13 KRH95075.1 - 1.4e-30 105.2 1.6 1.8e-30 104.8 0.3 1.8 1 1 1 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KRH95075.1 - 4.4e-24 84.5 3.4 7.5e-24 83.7 2.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNA_POL_M_15KD PF02150.11 KRH95078.1 - 9.8e-09 34.7 1.8 9.8e-09 34.7 1.2 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KRH95078.1 - 0.00051 19.6 2.7 0.00051 19.6 1.9 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 KRH95078.1 - 0.0094 15.7 9.7 0.092 12.5 0.3 2.5 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 KRH95078.1 - 0.16 11.4 0.5 0.16 11.4 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 KRH95078.1 - 0.19 12.0 10.9 1.5 9.2 2.7 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Thioredoxin_3 PF13192.1 KRH95078.1 - 0.28 11.0 0.2 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 Thioredoxin domain zf-ribbon_3 PF13248.1 KRH95078.1 - 0.31 10.3 11.6 0.22 10.7 3.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.21 KRH95078.1 - 0.58 10.6 0.1 0.58 10.6 0.1 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 KRH95078.1 - 0.6 10.1 0.1 0.6 10.1 0.0 3.4 3 1 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.16 KRH95078.1 - 0.72 9.7 11.1 4.4 7.2 0.6 3.1 2 1 1 3 3 3 0 FYVE zinc finger Nudix_N_2 PF14803.1 KRH95078.1 - 1.4 8.6 13.8 0.28 10.9 0.8 3.4 2 2 0 2 2 2 0 Nudix N-terminal Zn_ribbon_recom PF13408.1 KRH95078.1 - 1.5 9.1 8.1 3.5 7.9 2.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain FYVE_2 PF02318.11 KRH95078.1 - 1.6 8.6 7.1 0.62 9.9 0.4 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger NMD3 PF04981.8 KRH95078.1 - 1.7 7.6 12.3 0.18 10.9 1.9 2.2 1 1 0 2 2 2 0 NMD3 family Elf1 PF05129.8 KRH95078.1 - 3.4 7.4 9.4 1.5 8.5 1.1 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like GFA PF04828.9 KRH95078.1 - 3.7 7.5 12.4 0.78 9.7 0.8 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_4 PF13717.1 KRH95078.1 - 6.8 6.4 14.5 5.1 6.8 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Fip1 PF05182.8 KRH95079.1 - 4.1e-22 77.1 3.2 7.5e-22 76.3 2.2 1.4 1 0 0 1 1 1 1 Fip1 motif TPP1 PF10341.4 KRH95082.1 - 2.2e-09 37.2 1.0 3.2e-07 30.2 0.1 3.4 2 0 0 2 2 2 2 Shelterin complex subunit, TPP1/ACD XPG_I PF00867.13 KRH95084.1 - 8.3e-15 54.6 0.0 1e-13 51.1 0.0 2.6 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KRH95084.1 - 1.3e-10 41.4 0.4 1.6e-08 34.7 0.1 2.8 2 1 0 2 2 2 1 XPG N-terminal domain Clathrin PF00637.15 KRH95087.1 - 0.062 12.9 0.7 0.066 12.8 0.5 1.0 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF693 PF05113.8 KRH95087.1 - 0.34 9.7 3.7 0.34 9.7 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Motile_Sperm PF00635.21 KRH95088.1 - 6.4e-15 54.7 0.1 8.7e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Pro-rich PF15240.1 KRH95089.1 - 0.00061 19.9 18.7 0.0011 19.0 12.9 1.4 1 0 0 1 1 1 1 Proline-rich HATPase_c PF02518.21 KRH95091.1 - 0.0002 21.0 1.8 0.0013 18.3 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cnl2_NKP2 PF09447.5 KRH95092.1 - 0.009 15.6 0.3 0.04 13.5 0.2 2.1 1 0 0 1 1 1 1 Cnl2/NKP2 family protein S1FA PF04689.8 KRH95092.1 - 0.075 12.9 0.3 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 DNA binding protein S1FA DNA_pol3_delta2 PF13177.1 KRH95094.1 - 4.9e-08 32.7 0.5 4.8e-05 23.0 0.0 3.1 2 1 1 3 3 3 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 KRH95094.1 - 1.4e-05 24.3 0.3 0.017 14.2 0.1 2.8 1 1 2 3 3 3 2 Magnesium chelatase, subunit ChlI AAA PF00004.24 KRH95094.1 - 1.6e-05 25.1 1.5 0.0028 17.8 0.1 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KRH95094.1 - 2.6e-05 24.1 2.7 0.0015 18.3 0.0 3.5 1 1 2 3 3 3 1 AAA domain AAA_22 PF13401.1 KRH95094.1 - 0.0002 21.5 1.3 0.19 11.8 0.0 3.2 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KRH95094.1 - 0.00031 20.4 0.3 0.31 10.7 0.0 3.0 2 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KRH95094.1 - 0.0014 18.6 0.1 0.049 13.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain PhoH PF02562.11 KRH95094.1 - 0.0017 17.5 0.0 0.26 10.5 0.0 2.5 1 1 1 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 KRH95094.1 - 0.0021 18.8 0.3 0.0056 17.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KRH95094.1 - 0.008 15.6 0.0 2.6 7.5 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain GPDPase_memb PF10110.4 KRH95094.1 - 0.011 15.2 0.8 0.02 14.3 0.6 1.4 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase AAA_19 PF13245.1 KRH95094.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KRH95094.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KRH95094.1 - 0.024 13.6 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KRH95094.1 - 0.03 14.2 0.1 0.099 12.5 0.1 1.8 1 1 1 2 2 2 0 AAA domain DUF977 PF06163.6 KRH95094.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) NACHT PF05729.7 KRH95094.1 - 0.033 13.8 0.3 0.47 10.0 0.0 2.6 2 1 1 3 3 3 0 NACHT domain ResIII PF04851.10 KRH95094.1 - 0.045 13.5 0.1 0.3 10.8 0.0 2.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 KRH95094.1 - 0.049 13.0 0.2 0.21 10.9 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KRH95094.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KRH95094.1 - 0.094 13.0 3.6 0.98 9.7 0.9 3.3 1 1 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.2 KRH95095.1 - 1.5e-12 47.5 0.1 3.7e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Beta-Casp PF10996.3 KRH95095.1 - 2.3e-10 40.5 0.8 2.3e-09 37.2 0.0 3.0 2 1 1 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 KRH95095.1 - 1.8e-09 37.2 0.0 6.9e-09 35.3 0.0 2.0 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KRH95095.1 - 5.7e-09 35.8 0.0 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BUD22 PF09073.5 KRH95095.1 - 0.00086 18.4 34.8 0.0014 17.8 24.1 1.3 1 0 0 1 1 1 1 BUD22 DRMBL PF07522.9 KRH95095.1 - 0.0053 16.7 2.0 0.014 15.3 0.1 2.7 2 1 1 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_3 PF13483.1 KRH95095.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.21 KRH95096.1 - 1.1e-06 28.0 0.8 1.5e-06 27.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CPSF_A PF03178.10 KRH95098.1 - 9.5e-29 100.4 2.2 5.8e-23 81.4 0.2 3.0 3 0 0 3 3 3 2 CPSF A subunit region YjeF_N PF03853.10 KRH95100.1 - 5.5e-23 81.4 0.0 7.4e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus 14-3-3 PF00244.15 KRH95101.1 - 0.032 13.3 4.0 0.039 13.0 2.8 1.1 1 0 0 1 1 1 0 14-3-3 protein Casc1 PF12366.3 KRH95101.1 - 1.2 8.5 7.0 1.5 8.2 4.8 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 BBS2_Mid PF14783.1 KRH95102.1 - 0.0017 18.1 0.4 0.17 11.6 0.1 2.7 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 KRH95102.1 - 0.03 14.2 3.0 21 5.1 0.1 4.4 5 1 0 5 5 5 0 WD domain, G-beta repeat E2F_TDP PF02319.15 KRH95105.1 - 1.3e-14 53.4 0.0 3.7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.7 KRH95105.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.14 KRH95105.1 - 0.012 15.2 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3895 PF13034.1 KRH95105.1 - 0.058 12.8 0.1 0.27 10.7 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3895) HTH_36 PF13730.1 KRH95105.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Nic96 PF04097.9 KRH95106.1 - 2e-15 55.9 5.9 2.3e-13 49.1 2.1 2.3 2 0 0 2 2 2 2 Nup93/Nic96 HUN PF08729.5 KRH95107.1 - 0.026 14.3 1.9 0.077 12.8 1.3 1.8 1 0 0 1 1 1 0 HPC2 and ubinuclein domain AAA_assoc PF14363.1 KRH95107.1 - 0.08 12.9 0.3 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA SH PF01445.12 KRH95110.1 - 0.32 10.6 2.4 0.19 11.4 0.7 1.4 1 1 0 1 1 1 0 Viral small hydrophobic protein AAA PF00004.24 KRH95111.1 - 2.7e-39 134.4 0.2 1.4e-38 132.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH95111.1 - 2e-07 31.1 0.6 0.0013 18.8 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KRH95111.1 - 2.7e-07 30.3 0.3 0.0027 17.4 0.0 3.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 KRH95111.1 - 1e-06 28.5 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KRH95111.1 - 1.3e-06 27.6 0.0 3.6e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KRH95111.1 - 0.00015 21.6 1.9 0.0015 18.5 0.0 2.7 2 2 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KRH95111.1 - 0.00054 20.0 0.3 0.03 14.3 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain TIP49 PF06068.8 KRH95111.1 - 0.0015 17.3 0.1 0.005 15.5 0.0 1.9 1 1 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KRH95111.1 - 0.0016 18.3 0.1 0.0095 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KRH95111.1 - 0.002 18.9 0.1 0.013 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KRH95111.1 - 0.0027 17.3 1.4 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KRH95111.1 - 0.0049 16.0 0.1 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KRH95111.1 - 0.0058 16.2 0.1 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KRH95111.1 - 0.0086 15.4 0.2 0.18 11.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 KRH95111.1 - 0.018 15.2 0.0 0.053 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 KRH95111.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 KRH95111.1 - 0.035 13.7 0.4 1.4 8.5 0.0 3.0 1 1 1 3 3 3 0 NACHT domain AAA_19 PF13245.1 KRH95111.1 - 0.035 13.8 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KRH95111.1 - 0.044 14.1 0.6 0.25 11.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KRH95111.1 - 0.051 13.1 0.5 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KRH95111.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KRH95111.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter RINGv PF12906.2 KRH95112.1 - 1.1e-08 34.9 1.4 1.1e-08 34.9 0.9 1.6 2 0 0 2 2 2 1 RING-variant domain LSM PF01423.17 KRH95113.1 - 9.7e-10 37.8 0.6 1.2e-09 37.5 0.4 1.0 1 0 0 1 1 1 1 LSM domain CS PF04969.11 KRH95113.1 - 0.0077 16.7 0.2 0.0099 16.4 0.2 1.1 1 0 0 1 1 1 1 CS domain TFIIS_C PF01096.13 KRH95114.1 - 1.6e-16 59.6 1.7 1.6e-16 59.6 1.2 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ISL3 PF14690.1 KRH95114.1 - 0.032 14.2 0.6 0.47 10.5 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 NOB1_Zn_bind PF08772.6 KRH95114.1 - 0.06 13.1 3.3 1.9 8.3 0.0 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PhnA_Zn_Ribbon PF08274.7 KRH95114.1 - 0.087 12.6 0.8 0.087 12.6 0.5 2.0 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 KRH95114.1 - 0.13 11.5 13.1 0.38 10.0 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KRH95114.1 - 0.23 11.2 4.9 0.31 10.8 0.8 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 KRH95114.1 - 0.26 11.6 6.5 0.11 12.8 1.0 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 KRH95114.1 - 0.31 11.0 0.0 0.31 11.0 0.0 3.2 3 1 0 3 3 3 0 Zinc ribbon domain DUF2082 PF09855.4 KRH95114.1 - 0.43 10.4 0.1 0.43 10.4 0.1 2.4 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RING_4 PF14570.1 KRH95114.1 - 0.51 9.9 0.1 0.51 9.9 0.1 3.2 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 KRH95114.1 - 1 9.2 10.3 11 5.9 7.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KRH95114.1 - 1.4 8.5 13.5 0.41 10.2 0.6 4.1 3 2 1 4 4 4 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 KRH95114.1 - 1.6 8.2 11.1 0.082 12.4 0.9 3.1 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-H2C2_2 PF13465.1 KRH95114.1 - 1.6 9.1 8.5 8.6 6.8 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.7 KRH95114.1 - 2.1 7.7 9.5 1.8 7.9 1.6 3.2 2 2 1 3 3 3 0 TFIIB zinc-binding Auto_anti-p27 PF06677.7 KRH95114.1 - 4 7.2 5.9 1.6 8.5 0.3 2.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RNase_HII PF01351.13 KRH95116.1 - 5.4 6.5 8.9 3 7.4 0.3 2.6 2 0 0 2 2 2 0 Ribonuclease HII DUF668 PF05003.7 KRH95116.1 - 8.7 6.6 6.8 7.1 6.9 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF668) Ribosomal_L27e PF01777.13 KRH95117.1 - 1.5e-05 25.0 0.9 1.8e-05 24.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family CaKB PF03185.10 KRH95119.1 - 0.0046 16.3 0.1 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated potassium channel, beta subunit DUF1907 PF08925.6 KRH95119.1 - 0.064 12.3 0.1 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) TFIIS_C PF01096.13 KRH95120.1 - 2.7e-16 58.8 8.1 5e-16 58.0 5.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 KRH95120.1 - 4.8e-13 49.1 0.0 6.8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Histone PF00125.19 KRH95123.1 - 2.9e-20 72.1 0.0 4.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KRH95123.1 - 0.0032 17.6 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KRH95123.1 - 0.099 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PolyA_pol PF01743.15 KRH95124.1 - 5.4e-25 88.0 0.3 9.7e-24 83.9 0.0 2.5 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KRH95124.1 - 0.00036 20.0 0.5 0.0011 18.5 0.3 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A PyocinActivator PF11112.3 KRH95124.1 - 0.086 12.6 0.9 37 4.2 0.0 3.4 3 0 0 3 3 3 0 Pyocin activator protein PrtN Wzy_C PF04932.10 KRH95125.1 - 0.0019 18.0 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 O-Antigen ligase UPF0233 PF06781.7 KRH95125.1 - 0.63 9.7 7.7 1.5 8.5 0.0 3.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0233) Pkinase PF00069.20 KRH95128.1 - 1.1e-65 221.4 0.0 1.2e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KRH95128.1 - 7.2e-33 113.7 0.0 8.3e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KRH95128.1 - 0.0001 21.4 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KRH95128.1 - 0.01 15.6 0.0 0.13 11.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KRH95128.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KRH95128.1 - 0.037 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 KRH95129.1 - 5.9e-13 48.4 6.1 5.9e-13 48.4 4.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KRH95129.1 - 4.4e-08 33.0 6.7 4.4e-08 33.0 4.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH95129.1 - 7.2e-08 32.0 5.6 7.2e-08 32.0 3.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KRH95129.1 - 2.1e-07 30.9 4.3 2.1e-07 30.9 2.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KRH95129.1 - 2.4e-07 30.3 3.4 2.4e-07 30.3 2.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH95129.1 - 1.5e-06 27.7 6.6 1.5e-06 27.7 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KRH95129.1 - 0.00045 20.0 2.1 0.00045 20.0 1.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KRH95129.1 - 0.0093 15.9 9.3 0.5 10.3 6.5 2.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KRH95129.1 - 0.049 13.3 2.4 0.16 11.7 1.6 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 KRH95129.1 - 0.064 13.0 4.1 0.1 12.3 2.2 1.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Pex24p PF06398.6 KRH95129.1 - 1.2 7.9 7.1 0.042 12.6 0.7 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin zf-RING_4 PF14570.1 KRH95129.1 - 6.2 6.4 10.8 0.25 10.9 3.6 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KRH95129.1 - 8.3 5.9 12.2 2.6 7.5 5.0 2.6 2 1 0 2 2 2 0 P-11 zinc finger Hist_deacetyl PF00850.14 KRH95130.1 - 7.8e-78 261.9 0.2 1.5e-77 260.9 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain TPR_11 PF13414.1 KRH95131.1 - 1.8e-11 43.4 7.0 0.00012 21.6 0.1 4.2 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.1 KRH95131.1 - 2.8e-09 37.1 5.1 0.00045 20.4 0.1 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KRH95131.1 - 6.1e-06 26.0 7.2 0.0027 17.6 0.1 4.0 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KRH95131.1 - 9e-06 25.8 0.1 0.36 11.6 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KRH95131.1 - 6.6e-05 23.4 0.0 0.4 11.4 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KRH95131.1 - 0.00028 20.8 0.6 2.1 8.7 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KRH95131.1 - 0.00058 19.5 4.6 0.41 10.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 KRH95131.1 - 0.002 18.2 3.1 0.0077 16.3 0.1 2.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KRH95131.1 - 0.0021 17.5 3.4 1.1 8.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.4 KRH95131.1 - 0.01 15.6 0.1 0.054 13.3 0.1 2.3 1 1 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.1 KRH95131.1 - 0.026 14.3 4.1 6.9 6.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KRH95131.1 - 0.13 12.2 0.6 9 6.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.11 KRH95131.1 - 0.14 12.7 0.3 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat TPR_8 PF13181.1 KRH95131.1 - 0.14 11.9 6.3 0.96 9.3 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Ras PF00071.17 KRH95132.1 - 2e-54 183.3 2.3 2.3e-54 183.1 1.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH95132.1 - 1.7e-20 73.6 0.4 2.8e-20 73.0 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KRH95132.1 - 9.3e-17 60.8 0.9 1.1e-16 60.5 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KRH95132.1 - 5.6e-09 35.4 1.0 6.8e-09 35.2 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KRH95132.1 - 5.9e-08 32.3 0.9 1e-07 31.6 0.6 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KRH95132.1 - 6.5e-06 26.0 0.3 1.2e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KRH95132.1 - 0.00062 19.9 0.1 0.0019 18.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 KRH95132.1 - 0.0051 16.0 0.4 0.0099 15.1 0.2 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KRH95132.1 - 0.0051 16.0 0.1 0.012 14.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 KRH95132.1 - 0.0079 16.4 0.1 0.017 15.3 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KRH95132.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KRH95132.1 - 0.02 14.6 0.0 0.075 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KRH95132.1 - 0.02 15.7 1.1 0.07 13.9 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KRH95132.1 - 0.072 12.1 8.6 0.12 11.4 6.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KRH95132.1 - 0.082 12.3 0.9 0.16 11.4 0.6 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KRH95132.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KRH95132.1 - 0.23 11.1 2.6 1 9.0 1.8 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Met_10 PF02475.11 KRH95133.1 - 5.7e-37 127.2 0.1 1.4e-36 125.9 0.1 1.7 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 KRH95133.1 - 1.9e-10 40.3 0.0 4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 KRH95133.1 - 7.1e-07 28.9 1.1 3.2e-06 26.8 0.9 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KRH95133.1 - 1.4e-06 28.3 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KRH95133.1 - 5.2e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 KRH95133.1 - 0.00033 20.2 0.9 0.0013 18.2 0.2 2.1 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 KRH95133.1 - 0.00066 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 FmrO PF07091.6 KRH95133.1 - 0.00079 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 KRH95133.1 - 0.0017 17.5 0.1 0.0042 16.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltrans_SAM PF10672.4 KRH95133.1 - 0.0024 16.7 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase TRM PF02005.11 KRH95133.1 - 0.005 15.8 0.4 0.011 14.6 0.1 1.7 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.5 KRH95133.1 - 0.0061 16.1 0.9 0.016 14.7 0.6 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 KRH95133.1 - 0.037 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 KRH95133.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase TFIIE_beta PF02186.10 KRH95133.1 - 0.058 13.4 0.6 10 6.1 0.1 2.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain Methyltransf_12 PF08242.7 KRH95133.1 - 0.089 13.2 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UQ_con PF00179.21 KRH95134.1 - 4.5e-43 146.0 0.0 5e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KRH95134.1 - 0.019 14.8 0.1 0.028 14.3 0.1 1.4 1 1 0 1 1 1 0 RWD domain Ribosomal_S17 PF00366.15 KRH95135.1 - 1.6e-19 69.6 4.3 2.7e-19 68.9 2.5 1.7 1 1 1 2 2 2 1 Ribosomal protein S17 VirB3 PF05101.8 KRH95136.1 - 1.4 8.9 7.3 1.3 9.0 0.2 3.2 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein ATP_synt_H PF05493.8 KRH95136.1 - 9.5 6.3 9.8 8.9 6.4 1.3 3.5 3 1 1 4 4 4 0 ATP synthase subunit H Ras PF00071.17 KRH95137.1 - 1.3e-56 190.4 0.7 1.5e-56 190.2 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH95137.1 - 4.3e-19 69.1 0.1 6.6e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KRH95137.1 - 7.9e-16 57.7 0.2 9.4e-16 57.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KRH95137.1 - 6.3e-07 29.0 0.7 7.6e-06 25.4 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 KRH95137.1 - 3.3e-06 26.4 0.1 4.1e-06 26.1 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KRH95137.1 - 4.1e-06 26.1 0.4 1.8e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KRH95137.1 - 6.1e-06 26.1 0.6 9.7e-06 25.5 0.4 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KRH95137.1 - 0.00064 18.9 0.1 0.0015 17.7 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KRH95137.1 - 0.0021 17.9 0.2 0.0054 16.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KRH95137.1 - 0.0026 17.9 0.2 0.0063 16.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KRH95137.1 - 0.0047 16.1 0.0 0.0096 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KRH95137.1 - 0.0083 16.1 0.1 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 KRH95137.1 - 0.016 14.4 0.1 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 KRH95137.1 - 0.017 14.1 0.1 0.031 13.2 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 KRH95137.1 - 0.018 14.9 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KRH95137.1 - 0.022 14.2 0.2 0.04 13.4 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KRH95137.1 - 0.041 13.4 0.7 0.048 13.2 0.5 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KRH95137.1 - 0.047 13.9 0.4 0.059 13.6 0.3 1.5 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.8 KRH95137.1 - 0.052 12.3 0.2 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) G-alpha PF00503.15 KRH95137.1 - 0.059 12.0 1.0 3.4 6.2 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_2 PF07724.9 KRH95137.1 - 0.067 13.0 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Pox_A32 PF04665.7 KRH95137.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_5 PF07728.9 KRH95137.1 - 0.073 12.7 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KRH95137.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KRH95137.1 - 0.088 12.5 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KRH95137.1 - 0.099 12.2 0.1 0.22 11.1 0.0 1.5 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 KRH95137.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KRH95137.1 - 0.12 11.8 0.2 0.29 10.5 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.1 KRH95137.1 - 0.19 11.6 2.5 0.42 10.5 1.7 1.7 1 1 0 1 1 1 0 AAA domain SNARE PF05739.14 KRH95138.1 - 4.7e-11 42.2 3.7 1.3e-10 40.7 2.6 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KRH95138.1 - 0.0065 16.6 22.5 0.0088 16.1 6.5 3.5 2 1 1 3 3 3 1 Syntaxin VitD-bind_III PF09164.5 KRH95138.1 - 0.019 14.5 0.1 0.076 12.6 0.1 2.0 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF599 PF04654.7 KRH95138.1 - 0.078 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 YqzH PF14164.1 KRH95138.1 - 0.28 11.1 4.6 3.1 7.7 0.2 3.1 3 0 0 3 3 3 0 YqzH-like protein DUF2762 PF10960.3 KRH95138.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2762) CHD5 PF04420.9 KRH95138.1 - 1.1 8.8 12.4 1 8.9 2.7 3.0 2 1 0 2 2 2 0 CHD5-like protein RPA_C PF08784.6 KRH95138.1 - 4.5 7.7 5.8 0.3 11.5 0.3 1.8 2 0 0 2 2 2 0 Replication protein A C terminal DUF745 PF05335.8 KRH95138.1 - 6.2 6.2 7.4 5.1 6.5 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Noelin-1 PF12308.3 KRH95138.1 - 9.1 6.1 9.4 8 6.3 1.1 2.8 1 1 2 3 3 3 0 Neurogenesis glycoprotein DUF2789 PF10982.3 KRH95139.1 - 0.00098 19.0 0.2 0.0027 17.6 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2789) PUF PF00806.14 KRH95139.1 - 0.0089 15.4 0.2 0.5 9.9 0.0 3.6 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat AAA_10 PF12846.2 KRH95139.1 - 0.2 11.0 1.9 1.8 7.9 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain Imm46 PF15585.1 KRH95139.1 - 0.28 11.2 5.4 2.3 8.2 0.0 3.5 3 1 1 4 4 4 0 Immunity protein 46 HD PF01966.17 KRH95139.1 - 1.2 9.1 4.4 0.7 9.9 0.8 2.5 2 1 1 3 3 3 0 HD domain Ydc2-catalyt PF09159.5 KRH95139.1 - 7.9 5.8 10.8 2 7.8 5.0 1.7 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 EF-hand_7 PF13499.1 KRH95140.1 - 8.1e-13 48.3 10.1 1.6e-05 24.9 1.9 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KRH95140.1 - 8.5e-12 43.4 2.9 0.016 14.5 0.3 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KRH95140.1 - 5.3e-09 35.2 4.4 0.047 13.5 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KRH95140.1 - 2.5e-06 26.9 5.0 0.24 11.0 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KRH95140.1 - 0.0067 15.7 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 EF hand YchF-GTPase_C PF06071.8 KRH95141.1 - 5.7e-38 128.5 2.1 6.1e-38 128.4 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KRH95141.1 - 4.8e-19 68.4 0.0 1.2e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KRH95141.1 - 2.8e-08 33.1 0.0 7.6e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KRH95141.1 - 0.0082 15.9 0.9 3 7.6 0.0 3.1 3 1 1 4 4 4 2 Dynamin family ArgK PF03308.11 KRH95141.1 - 0.031 13.0 0.0 0.072 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein TGS PF02824.16 KRH95141.1 - 0.032 14.0 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 TGS domain ABC_tran PF00005.22 KRH95141.1 - 0.081 13.2 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 KRH95141.1 - 0.11 12.4 1.3 0.62 9.9 0.0 2.7 2 1 0 3 3 3 0 AAA domain zf-C2H2 PF00096.21 KRH95142.1 - 2.2e-12 46.5 32.4 0.00073 19.7 0.8 5.5 4 1 1 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KRH95142.1 - 4.4e-06 26.6 28.2 0.093 13.1 0.3 5.5 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KRH95142.1 - 2.2e-05 24.4 29.0 0.041 14.0 0.3 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KRH95142.1 - 0.00047 19.9 20.4 0.063 13.1 0.0 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KRH95142.1 - 0.00049 20.2 4.4 0.016 15.4 0.2 5.8 6 1 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.2 KRH95142.1 - 0.077 13.2 0.2 0.077 13.2 0.2 5.6 5 1 1 6 6 6 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KRH95142.1 - 0.17 11.6 0.3 0.17 11.6 0.2 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Yippee-Mis18 PF03226.9 KRH95142.1 - 0.19 11.7 12.7 0.029 14.4 4.9 2.2 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-ribbon_8 PF09723.5 KRH95142.1 - 0.56 10.2 13.0 5.2 7.1 0.1 4.4 4 0 0 4 4 4 0 Zinc ribbon domain Trm112p PF03966.11 KRH95142.1 - 1.3 9.4 4.2 33 4.9 1.3 3.3 2 2 0 2 2 2 0 Trm112p-like protein zf-CHY PF05495.7 KRH95142.1 - 1.3 9.1 21.9 0.5 10.5 4.7 3.4 1 1 2 3 3 3 0 CHY zinc finger C1_4 PF07975.7 KRH95142.1 - 2 8.4 18.6 10 6.1 0.1 3.9 2 1 1 3 3 3 0 TFIIH C1-like domain zf-Di19 PF05605.7 KRH95142.1 - 8.5 6.5 16.8 1.6 8.8 0.2 3.9 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 KRH95142.1 - 8.7 6.2 14.3 10 5.9 0.5 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain LSM PF01423.17 KRH95143.1 - 4.1e-11 42.2 1.7 6.5e-11 41.6 1.2 1.3 1 0 0 1 1 1 1 LSM domain Rad21_Rec8_N PF04825.8 KRH95143.1 - 0.038 13.9 0.6 0.048 13.6 0.4 1.2 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein G-7-MTase PF12803.2 KRH95143.1 - 0.11 11.6 0.3 0.18 10.9 0.1 1.5 1 1 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF2913 PF11140.3 KRH95144.1 - 0.021 14.1 0.2 0.054 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) DUF883 PF05957.8 KRH95144.1 - 0.13 12.6 0.0 0.86 10.0 0.0 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mit_KHE1 PF10173.4 KRH95144.1 - 0.56 10.0 3.0 2.2 8.0 2.0 2.2 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF2112 PF09885.4 KRH95146.1 - 0.078 12.6 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) DUF4632 PF15451.1 KRH95147.1 - 1.9 8.4 0.0 1.9 8.4 0.0 6.1 4 1 2 7 7 7 0 Domain of unknown function (DUF4632) Fork_head PF00250.13 KRH95149.1 - 1.4e-29 101.9 1.1 2.3e-29 101.2 0.8 1.3 1 0 0 1 1 1 1 Fork head domain OST-HTH PF12872.2 KRH95149.1 - 0.09 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain DsrC PF04358.8 KRH95151.1 - 0.012 15.8 0.9 0.81 9.9 0.0 2.4 2 1 0 2 2 2 0 DsrC like protein Nop10p PF04135.7 KRH95153.1 - 6e-08 32.3 0.6 3.6e-07 29.8 0.4 1.9 1 1 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Homeobox PF00046.24 KRH95154.1 - 6.1e-15 54.5 0.7 1.1e-14 53.7 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 KRH95154.1 - 0.03 13.9 0.3 0.072 12.7 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Homeobox_KN PF05920.6 KRH95154.1 - 0.038 13.6 0.3 0.075 12.7 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homeobox PF00046.24 KRH95157.1 - 3.7e-13 48.8 0.8 6.7e-13 48.0 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KRH95157.1 - 0.0036 16.9 0.2 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.17 KRH95157.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix DUF658 PF04936.7 KRH95157.1 - 0.027 14.3 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Actin PF00022.14 KRH95160.1 - 1.6e-147 491.0 0.0 1.8e-147 490.9 0.0 1.0 1 0 0 1 1 1 1 Actin Peptidase_M18 PF02127.10 KRH95161.1 - 1.4e-57 195.1 0.0 1e-56 192.3 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KRH95161.1 - 6.9e-06 25.0 0.0 1.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MCM PF00493.18 KRH95163.1 - 8.4e-104 346.9 1.6 1.1e-103 346.5 0.4 1.7 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 KRH95163.1 - 7.5e-10 38.3 0.0 1.4e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KRH95163.1 - 9.6e-08 31.8 0.0 4.3e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KRH95163.1 - 0.00063 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KRH95163.1 - 0.035 14.3 0.1 0.14 12.3 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vfa1 PF08432.5 KRH95163.1 - 0.59 10.1 6.8 0.08 12.9 0.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1240 PF06836.7 KRH95164.1 - 0.27 11.4 1.8 0.54 10.5 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) PS_Dcarbxylase PF02666.10 KRH95166.1 - 4.2e-40 137.2 0.0 7.2e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF883 PF05957.8 KRH95167.1 - 0.015 15.6 0.2 0.015 15.6 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KRH95167.1 - 0.016 14.7 14.8 0.03 13.8 0.2 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain PhaP_Bmeg PF09602.5 KRH95167.1 - 0.036 13.8 12.4 0.044 13.6 8.6 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) GvpL_GvpF PF06386.6 KRH95167.1 - 0.13 11.8 5.5 0.16 11.5 3.8 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Molybdopterin PF00384.17 KRH95167.1 - 0.18 10.5 4.4 0.083 11.6 1.8 1.3 1 1 0 1 1 1 0 Molybdopterin oxidoreductase DUF2422 PF10337.4 KRH95167.1 - 0.32 9.7 2.8 0.38 9.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) YtxH PF12732.2 KRH95167.1 - 0.51 10.7 17.6 1.2e+03 -0.1 12.2 2.4 1 1 0 1 1 1 0 YtxH-like protein Occludin_ELL PF07303.8 KRH95167.1 - 1.1 10.0 19.3 1.6 9.4 3.4 2.2 1 1 1 2 2 2 0 Occludin homology domain AAA_23 PF13476.1 KRH95167.1 - 1.3 9.3 18.4 1.6 9.0 12.7 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 KRH95167.1 - 1.7 7.7 11.6 1.9 7.5 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GBP_C PF02841.9 KRH95167.1 - 3.5 6.7 25.3 10 5.2 17.5 1.7 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.9 KRH95167.1 - 7.6 6.4 26.6 20 5.0 18.4 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Med1 PF10744.4 KRH95170.1 - 0.087 11.5 0.3 0.086 11.5 0.2 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 DnaJ PF00226.26 KRH95171.1 - 0.00015 21.4 1.7 0.00015 21.4 1.2 2.4 2 0 0 2 2 2 1 DnaJ domain LHH PF14411.1 KRH95171.1 - 8.3 6.7 7.4 0.35 11.1 0.3 2.3 3 0 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Rcd1 PF04078.8 KRH95172.1 - 3.6e-50 170.2 6.1 4.7e-50 169.8 4.2 1.3 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sdh5 PF03937.11 KRH95172.1 - 0.55 9.9 0.0 0.55 9.9 0.0 2.4 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase AAA PF00004.24 KRH95173.1 - 4.4e-19 68.9 0.3 4.3e-12 46.3 0.2 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH95173.1 - 2.1e-05 24.6 0.0 0.013 15.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KRH95173.1 - 0.00026 20.1 0.0 0.00095 18.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KRH95173.1 - 0.0003 20.4 13.4 0.0003 20.4 9.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KRH95173.1 - 0.00077 19.4 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KRH95173.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 KRH95173.1 - 0.0018 17.7 0.1 0.0055 16.2 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 KRH95173.1 - 0.0019 18.1 2.0 0.0092 15.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KRH95173.1 - 0.0031 17.0 0.0 0.01 15.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.15 KRH95173.1 - 0.0033 17.0 0.3 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.12 KRH95173.1 - 0.0037 16.6 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 KRH95173.1 - 0.004 16.8 0.1 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 KRH95173.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KRH95173.1 - 0.0071 17.1 0.4 0.071 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 KRH95173.1 - 0.037 13.1 0.0 0.095 11.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KRH95173.1 - 0.074 13.0 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KRH95173.1 - 0.13 12.1 0.0 0.13 12.1 0.0 4.1 2 2 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KRH95173.1 - 2.9 8.2 21.9 0.072 13.4 5.0 4.0 3 1 0 3 3 3 0 AAA domain NMT PF01233.14 KRH95174.1 - 6.8e-06 25.7 0.1 6.5e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.19 KRH95174.1 - 0.014 15.4 0.0 0.066 13.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KRH95174.1 - 0.041 14.0 1.3 0.41 10.8 0.0 3.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain YopJ PF03421.11 KRH95176.1 - 0.19 11.5 2.3 5.5 6.8 0.1 2.6 1 1 2 3 3 3 0 YopJ Serine/Threonine acetyltransferase Nop25 PF09805.4 KRH95179.1 - 0.0026 17.8 24.7 0.0028 17.7 17.1 1.0 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) DUF2413 PF10310.4 KRH95179.1 - 0.58 8.9 13.6 0.55 8.9 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mit_ribos_Mrp51 PF11709.3 KRH95179.1 - 0.75 8.9 9.8 0.85 8.7 6.8 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF2514 PF10721.4 KRH95179.1 - 1.3 8.7 7.3 1.6 8.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Med19 PF10278.4 KRH95179.1 - 4.1 7.0 21.7 4.7 6.8 15.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SR-25 PF10500.4 KRH95179.1 - 4.7 6.6 19.8 6 6.2 13.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDHD PF02862.12 KRH95179.1 - 4.7 6.9 8.8 4.7 6.9 6.1 1.1 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 KRH95179.1 - 9.7 6.2 10.9 10 6.0 7.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF4309 PF14172.1 KRH95180.1 - 0.049 13.6 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) O-antigen_lig PF13425.1 KRH95180.1 - 0.071 13.0 0.6 0.098 12.6 0.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BAR_2 PF10455.4 KRH95182.1 - 6.3e-08 31.8 13.6 8.8e-08 31.4 9.3 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Corona_S2 PF01601.11 KRH95182.1 - 0.014 13.5 1.0 0.015 13.4 0.7 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Syntaxin PF00804.20 KRH95182.1 - 0.02 15.0 16.0 0.054 13.6 8.6 2.5 2 1 0 2 2 2 0 Syntaxin CENP-F_leu_zip PF10473.4 KRH95182.1 - 0.023 14.5 10.0 0.033 14.0 4.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ig_J_chain PF15097.1 KRH95182.1 - 0.039 13.5 0.5 0.061 12.8 0.3 1.3 1 0 0 1 1 1 0 Immunoglobulin J chain OGG_N PF07934.7 KRH95182.1 - 0.047 13.6 2.4 0.19 11.7 0.5 2.4 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Hrs_helical PF12210.3 KRH95182.1 - 0.053 13.7 10.2 1.3 9.3 0.6 3.7 2 1 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF1664 PF07889.7 KRH95182.1 - 0.084 12.6 8.4 0.22 11.3 1.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF592 PF04574.8 KRH95182.1 - 0.12 11.9 4.5 0.15 11.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF592) MADF_DNA_bdg PF10545.4 KRH95182.1 - 0.17 12.0 3.7 15 5.8 1.1 3.0 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4373 PF14297.1 KRH95182.1 - 0.19 12.0 1.7 1.7 8.9 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4373) Prefoldin_2 PF01920.15 KRH95182.1 - 0.82 9.4 13.3 2.5 7.9 2.1 3.6 3 1 0 3 3 3 0 Prefoldin subunit DUF1759 PF03564.10 KRH95182.1 - 1.8 8.3 10.3 30 4.3 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) BLOC1_2 PF10046.4 KRH95182.1 - 3.9 7.6 16.6 0.86 9.7 0.2 3.1 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 KRH95182.1 - 4.5 6.1 9.4 11 4.8 6.4 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pox_VLTF3 PF04947.9 KRH95182.1 - 5.6 6.4 12.9 0.37 10.2 4.7 2.0 2 1 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like IncA PF04156.9 KRH95182.1 - 5.7 6.4 9.3 5.9 6.4 3.9 2.2 2 1 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KRH95182.1 - 8.2 6.4 8.8 1.5 8.8 0.4 2.9 2 1 2 4 4 4 0 bZIP transcription factor CAF1 PF04857.15 KRH95187.1 - 1.5e-54 185.0 1.7 2.2e-54 184.5 1.2 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease PAT1 PF09770.4 KRH95188.1 - 2.7e-05 22.6 0.2 2.7e-05 22.6 0.2 2.4 3 0 0 3 3 3 2 Topoisomerase II-associated protein PAT1 GIT_SHD PF08518.6 KRH95189.1 - 1.7e-07 30.4 5.6 0.0018 17.6 0.1 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT tRNA-synt_1d PF00750.14 KRH95190.1 - 2.7e-60 204.0 13.4 3.4e-58 197.1 6.9 2.7 1 1 1 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KRH95190.1 - 2.2e-19 69.5 0.0 7.6e-19 67.8 0.0 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2274 PF10038.4 KRH95190.1 - 0.2 11.8 2.3 3.5 7.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) Arg_tRNA_synt_N PF03485.11 KRH95190.1 - 0.59 10.7 5.2 1.7 9.2 1.3 2.9 2 1 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain Glycos_transf_2 PF00535.21 KRH95191.1 - 1.9e-25 89.5 0.2 2.6e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 KRH95191.1 - 8.3e-06 25.0 0.2 1.1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KRH95191.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KRH95191.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KRH95191.1 - 0.063 13.6 0.0 0.15 12.4 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase family 2 TPR_11 PF13414.1 KRH95192.1 - 3.2e-12 45.9 0.1 1.3e-09 37.5 0.0 3.1 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 KRH95192.1 - 1.6e-06 28.6 0.1 0.0011 19.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KRH95192.1 - 5.8e-05 22.5 8.8 0.071 12.7 0.3 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KRH95192.1 - 0.00049 19.7 12.4 0.0067 16.2 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KRH95192.1 - 0.00056 19.7 5.1 0.43 10.5 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KRH95192.1 - 0.0057 16.3 18.3 0.0058 16.3 0.2 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KRH95192.1 - 0.048 14.1 1.5 32 5.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KRH95192.1 - 0.083 12.7 3.4 49 4.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KRH95192.1 - 0.086 13.1 0.0 1 9.7 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KRH95192.1 - 0.087 13.0 2.8 20 5.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.17 KRH95193.1 - 5.7e-35 120.4 0.1 7.9e-35 119.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Spb1_C PF07780.7 KRH95193.1 - 0.057 12.8 0.6 0.089 12.2 0.4 1.2 1 0 0 1 1 1 0 Spb1 C-terminal domain Ribos_L4_asso_C PF14374.1 KRH95193.1 - 0.13 12.1 0.9 0.74 9.7 0.0 2.7 3 0 0 3 3 3 0 60S ribosomal protein L4 C-terminal domain SRP19 PF01922.12 KRH95194.1 - 1.3e-19 70.5 1.6 1.3e-19 70.5 1.1 2.0 1 1 1 2 2 2 1 SRP19 protein DUF4604 PF15377.1 KRH95194.1 - 0.31 11.2 11.9 0.46 10.6 8.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Cas_Csa5 PF09702.5 KRH95194.1 - 1.7 8.7 4.5 0.68 10.0 1.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) TIM PF00121.13 KRH95195.1 - 1.5e-70 237.0 0.4 1.8e-70 236.7 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.19 KRH95195.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Muted PF14942.1 KRH95195.1 - 0.097 12.5 1.0 0.25 11.2 0.2 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Lectin_leg-like PF03388.8 KRH95196.1 - 7.9e-10 38.2 0.1 5.4e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Legume-like lectin family RNA_pol_Rpb1_2 PF00623.15 KRH95198.1 - 0.0069 16.3 0.6 1.7 8.5 0.0 2.3 1 1 2 3 3 3 3 RNA polymerase Rpb1, domain 2 YabP PF07873.6 KRH95198.1 - 0.012 15.1 6.5 4.3 6.9 0.5 4.2 1 1 4 5 5 5 0 YabP family Asp_protease_2 PF13650.1 KRH95198.1 - 0.077 13.5 0.0 0.63 10.5 0.0 2.2 1 1 0 1 1 1 0 Aspartyl protease CBM49 PF09478.5 KRH95198.1 - 0.16 12.0 3.1 8.7 6.5 0.7 2.4 1 1 1 2 2 2 0 Carbohydrate binding domain CBM49 Sulfolobus_pRN PF05584.6 KRH95198.1 - 0.41 10.6 8.1 3.7 7.5 1.8 2.7 1 1 2 3 3 3 0 Sulfolobus plasmid regulatory protein C-term_anchor PF13461.1 KRH95198.1 - 0.53 10.7 11.2 36 4.9 0.6 4.4 1 1 2 3 3 3 0 Cell-wall surface anchor repeat Peptidase_S74 PF13884.1 KRH95198.1 - 1.2 9.3 7.0 5e+02 0.9 4.8 3.6 1 1 0 1 1 1 0 Chaperone of endosialidase Endonuc_subdom PF09062.5 KRH95198.1 - 9.1 7.1 9.3 3.3e+02 2.1 6.4 2.3 1 1 0 1 1 1 0 PI-PfuI Endonuclease subdomain MutS_V PF00488.16 KRH95200.1 - 1.2e-52 178.6 0.0 2.7e-52 177.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KRH95200.1 - 1.6e-16 60.7 1.1 2.9e-16 59.8 0.7 1.4 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 KRH95200.1 - 0.034 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KRH95200.1 - 4.1 7.6 5.6 1.4 9.1 0.1 2.7 3 0 0 3 3 3 0 ABC transporter BHD_1 PF10403.4 KRH95202.1 - 6.4e-12 44.8 0.5 1.5e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 KRH95202.1 - 1.1e-09 37.8 1.9 1.8e-08 33.9 0.1 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 KRH95202.1 - 0.027 14.7 0.2 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 SPC12 PF06645.8 KRH95203.1 - 1.4e-18 66.4 1.1 1.6e-18 66.2 0.8 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Rab5ip PF07019.7 KRH95203.1 - 0.068 13.3 1.4 0.095 12.8 1.0 1.3 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) ZYG-11_interact PF05884.7 KRH95203.1 - 0.12 11.4 0.5 0.11 11.6 0.4 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 Myc_target_1 PF15179.1 KRH95203.1 - 0.13 11.8 0.6 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Myc target protein 1 DUF165 PF02592.10 KRH95203.1 - 0.44 10.7 4.1 1.5 9.0 2.9 1.8 1 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 SdpI PF13630.1 KRH95203.1 - 1 9.0 6.3 1.3 8.8 4.3 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family MAT1 PF06391.8 KRH95205.1 - 7.9e-15 54.9 6.8 1e-14 54.6 4.7 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KRH95205.1 - 9e-06 25.3 7.4 1.6e-05 24.5 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KRH95205.1 - 9.6e-06 25.1 8.2 2.6e-05 23.7 5.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH95205.1 - 4.2e-05 23.4 8.9 0.00012 22.0 6.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH95205.1 - 0.00076 19.0 6.2 0.0017 17.9 4.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KRH95205.1 - 0.0042 16.6 9.9 0.19 11.3 7.6 2.3 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zinc_ribbon_2 PF13240.1 KRH95205.1 - 0.015 14.7 2.0 3.6 7.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 KRH95205.1 - 0.018 14.8 7.9 0.062 13.1 5.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.1 KRH95205.1 - 0.036 13.9 8.5 0.13 12.1 5.9 1.8 1 1 0 1 1 1 0 Ring finger domain TF_Zn_Ribbon PF08271.7 KRH95205.1 - 0.059 12.6 6.3 0.39 10.0 1.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_6 PF14835.1 KRH95205.1 - 0.82 9.4 7.0 7.5 6.4 4.9 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Auto_anti-p27 PF06677.7 KRH95205.1 - 1.2 8.9 5.9 2.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2072 PF09845.4 KRH95205.1 - 1.5 8.7 5.1 3.8 7.4 3.5 1.8 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-ribbon_3 PF13248.1 KRH95205.1 - 2 7.7 9.9 3 7.1 0.2 2.7 1 1 1 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KRH95205.1 - 2.8 7.9 6.9 20 5.2 0.1 2.7 2 1 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 KRH95205.1 - 5 7.0 8.6 8.7 6.2 1.9 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_S21e PF01249.13 KRH95206.1 - 3.6e-09 36.4 0.0 4.2e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e PLAC8 PF04749.12 KRH95208.1 - 0.042 14.4 4.4 0.064 13.8 3.1 1.3 1 0 0 1 1 1 0 PLAC8 family T4_Gp59_C PF08994.5 KRH95209.1 - 0.0023 18.0 0.9 3.5 7.8 0.1 2.8 2 0 0 2 2 2 2 T4 gene Gp59 loader of gp41 DNA helicase C-term DNA_Packaging_2 PF11123.3 KRH95209.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 DNA packaging protein UDPG_MGDP_dh_N PF03721.9 KRH95209.1 - 0.065 12.6 2.9 2 7.7 0.0 3.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Na_Ca_ex PF01699.19 KRH95211.1 - 9.5e-20 70.6 33.7 3.4e-13 49.3 5.2 3.2 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Sad1_UNC PF07738.8 KRH95212.1 - 1.1e-08 34.9 0.5 2.7e-08 33.7 0.3 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ribosomal_L18ae PF01775.12 KRH95213.1 - 1.3e-27 96.1 1.5 1.8e-27 95.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Peptidase_M4 PF01447.13 KRH95213.1 - 0.031 14.4 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain AAA_5 PF07728.9 KRH95214.1 - 1.1e-77 258.4 0.1 8.5e-23 80.6 0.0 7.0 7 1 0 7 7 6 5 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KRH95214.1 - 1.8e-32 111.6 0.0 5.5e-08 32.4 0.0 6.0 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KRH95214.1 - 1.1e-24 87.1 0.7 9.8e-06 25.7 0.0 5.2 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH95214.1 - 3.6e-18 65.9 11.8 5.2e-05 23.4 0.1 6.5 5 1 0 5 5 5 4 AAA domain AAA_16 PF13191.1 KRH95214.1 - 1.6e-16 60.8 0.0 0.0011 18.9 0.0 4.8 4 0 0 4 4 4 3 AAA ATPase domain AAA_17 PF13207.1 KRH95214.1 - 4.5e-13 50.0 6.9 0.0015 19.3 0.0 7.0 6 0 0 6 6 5 2 AAA domain AAA_33 PF13671.1 KRH95214.1 - 3.5e-12 46.3 0.0 0.0004 20.2 0.0 5.4 5 1 0 5 5 5 2 AAA domain AAA_18 PF13238.1 KRH95214.1 - 1.1e-11 45.1 18.2 0.0025 18.1 0.0 8.0 6 0 0 6 6 5 3 AAA domain T2SE PF00437.15 KRH95214.1 - 1.2e-10 40.7 0.0 0.091 11.6 0.0 4.5 4 0 0 4 4 4 3 Type II/IV secretion system protein Sigma54_activat PF00158.21 KRH95214.1 - 4e-10 39.4 0.0 0.13 11.7 0.0 4.9 5 0 0 5 5 4 3 Sigma-54 interaction domain RNA_helicase PF00910.17 KRH95214.1 - 4.4e-09 36.4 0.0 1 9.5 0.0 5.7 4 0 0 4 4 4 3 RNA helicase AAA_19 PF13245.1 KRH95214.1 - 1.5e-07 31.0 0.0 0.044 13.5 0.0 4.1 4 0 0 4 4 4 2 Part of AAA domain NACHT PF05729.7 KRH95214.1 - 1.5e-07 31.2 0.3 0.076 12.6 0.0 5.0 4 1 0 4 4 4 1 NACHT domain UPF0079 PF02367.12 KRH95214.1 - 2.1e-07 30.6 0.0 0.49 10.0 0.0 5.1 5 0 0 5 5 4 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KRH95214.1 - 2.9e-07 29.8 0.1 0.28 10.3 0.0 4.7 4 0 0 4 4 4 2 Protein of unknown function, DUF258 RuvB_N PF05496.7 KRH95214.1 - 2.9e-07 29.7 1.7 0.7 8.8 0.0 6.0 4 2 1 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KRH95214.1 - 1.4e-06 28.3 1.1 0.73 9.8 0.0 5.8 6 0 0 6 6 5 1 Sigma-54 interaction domain NTPase_1 PF03266.10 KRH95214.1 - 3.2e-06 26.9 1.2 0.56 9.9 0.1 4.4 4 0 0 4 4 4 2 NTPase SRP54 PF00448.17 KRH95214.1 - 1.2e-05 24.8 0.1 0.71 9.2 0.0 3.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KRH95214.1 - 1.5e-05 25.0 0.3 8.1 6.3 0.0 4.7 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.12 KRH95214.1 - 3.2e-05 23.4 1.3 0.28 10.5 0.0 4.6 4 1 0 4 4 4 1 IstB-like ATP binding protein AAA_6 PF12774.2 KRH95214.1 - 6.8e-05 22.5 0.5 0.57 9.6 0.0 4.8 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region D1 DEAD PF00270.24 KRH95214.1 - 8.6e-05 22.0 0.0 0.096 12.1 0.0 3.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 KRH95214.1 - 9.8e-05 21.6 0.4 6.1 5.9 0.0 5.5 5 1 0 5 5 4 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KRH95214.1 - 0.00017 21.2 3.9 1.9 8.1 0.1 4.7 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KRH95214.1 - 0.0028 17.2 0.0 7.1 6.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 KRH95214.1 - 0.0029 17.1 0.2 17 4.9 0.0 4.5 5 0 0 5 5 4 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KRH95214.1 - 0.036 13.5 0.1 33 3.8 0.0 3.8 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KRH95214.1 - 0.18 11.2 0.0 52 3.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain Aldo_ket_red PF00248.16 KRH95215.1 - 3.3e-08 32.7 0.0 3.3e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KRH95217.1 - 1.5e-46 158.5 0.2 2.1e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NIF3 PF01784.13 KRH95217.1 - 0.052 13.1 0.5 0.16 11.5 0.3 1.9 1 1 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Ras PF00071.17 KRH95219.1 - 1.4e-52 177.3 0.1 1.6e-52 177.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KRH95219.1 - 3.5e-18 66.2 0.0 6.8e-18 65.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KRH95219.1 - 1.2e-13 50.6 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KRH95219.1 - 6.4e-09 35.2 0.1 7.4e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KRH95219.1 - 9.7e-06 25.5 0.0 1.5e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KRH95219.1 - 0.00018 20.9 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KRH95219.1 - 0.014 15.2 0.5 0.034 14.0 0.1 1.9 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 KRH95219.1 - 0.11 12.3 0.5 2.2 8.0 0.0 2.5 2 1 1 3 3 3 0 Dynamin family G-alpha PF00503.15 KRH95219.1 - 0.2 10.3 4.3 0.85 8.2 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AP_endonuc_2 PF01261.19 KRH95221.1 - 4.4e-27 94.7 0.1 6.6e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel YpzG PF14139.1 KRH95222.1 - 0.26 11.2 2.4 0.34 10.8 1.7 1.3 1 1 0 1 1 1 0 YpzG-like protein Prenyltrans PF00432.16 KRH95225.1 - 4.2e-27 93.3 0.1 9.3e-09 34.7 0.0 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KRH95225.1 - 3.8e-22 78.8 0.0 3.5e-10 40.2 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KRH95225.1 - 6e-07 29.4 0.0 0.23 11.4 0.0 3.5 2 1 1 3 3 3 3 Prenyltransferase-like A2M_comp PF07678.9 KRH95225.1 - 0.075 12.2 0.0 1.4 8.0 0.0 2.6 2 1 0 3 3 3 0 A-macroglobulin complement component HBS1_N PF08938.5 KRH95225.1 - 0.14 12.2 0.1 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 HBS1 N-terminus EMP24_GP25L PF01105.19 KRH95226.1 - 3.1e-09 36.8 0.4 3.9e-09 36.4 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1034 PF06280.7 KRH95226.1 - 0.037 14.4 0.2 0.056 13.8 0.1 1.3 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) Transketolase_N PF00456.16 KRH95228.1 - 1.1e-75 254.5 0.1 1.9e-75 253.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KRH95228.1 - 3.3e-31 108.1 0.0 2.5e-29 102.0 0.0 2.5 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KRH95228.1 - 2.9e-11 43.3 0.0 9e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.15 KRH95228.1 - 5.3e-07 28.6 0.0 5.3e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KRH95228.1 - 1.4e-05 24.7 0.2 6.1e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KRH95228.1 - 0.021 13.7 8.2 0.05 12.5 0.1 3.2 3 1 1 4 4 4 0 1-deoxy-D-xylulose-5-phosphate synthase ThiF PF00899.16 KRH95229.1 - 2.2e-23 82.5 1.7 2.6e-23 82.3 0.1 1.8 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.1 KRH95229.1 - 0.0047 17.1 0.7 0.075 13.2 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Transcrip_act PF04949.8 KRH95229.1 - 0.098 12.2 3.8 0.053 13.1 1.2 1.6 2 0 0 2 2 2 0 Transcriptional activator Cytidylate_kin PF02224.13 KRH95230.1 - 2.9e-37 127.5 0.5 3.9e-37 127.1 0.3 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.1 KRH95230.1 - 3.6e-11 43.9 1.3 1.5e-10 41.9 0.8 2.0 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 KRH95230.1 - 6.8e-06 26.1 3.2 1.7e-05 24.7 2.2 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.1 KRH95230.1 - 9.8e-06 25.8 0.2 3.1e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KRH95230.1 - 0.0032 17.3 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 KRH95230.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH95230.1 - 0.05 13.3 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain KTI12 PF08433.5 KRH95230.1 - 0.057 12.6 0.1 0.21 10.7 0.0 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 KRH95230.1 - 0.064 13.1 0.4 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.7 KRH95230.1 - 0.13 11.8 0.0 1.1 8.9 0.0 2.2 2 1 1 3 3 3 0 NACHT domain ENTH PF01417.15 KRH95230.1 - 0.15 11.9 1.1 0.43 10.4 0.7 1.8 1 1 1 2 2 2 0 ENTH domain ThiF PF00899.16 KRH95231.1 - 3e-38 130.6 0.2 6e-38 129.7 0.1 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KRH95231.1 - 3.2e-19 68.3 1.5 7.3e-19 67.1 1.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KRH95231.1 - 0.0017 18.7 0.1 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.15 KRH95231.1 - 0.0022 18.0 0.1 0.0075 16.3 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KRH95231.1 - 0.034 13.1 0.1 0.073 12.0 0.0 1.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase SMC_N PF02463.14 KRH95232.1 - 1.4e-14 53.9 32.8 6.9e-11 41.8 15.8 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KRH95232.1 - 8.9e-13 48.2 1.3 2.6e-12 46.7 0.1 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KRH95232.1 - 3.8e-07 30.6 26.9 3.8e-07 30.6 18.7 4.3 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 KRH95232.1 - 0.002 17.6 0.1 0.0052 16.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KRH95232.1 - 0.011 16.0 22.2 0.29 11.4 0.2 4.4 3 1 0 3 3 3 0 ABC transporter SbcCD_C PF13558.1 KRH95232.1 - 0.014 15.2 0.1 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KRH95232.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PLU-1 PF08429.6 KRH95233.1 - 0.00059 18.8 1.2 0.00062 18.7 0.8 1.0 1 0 0 1 1 1 1 PLU-1-like protein CENP_C_N PF15622.1 KRH95233.1 - 0.02 14.1 0.6 0.024 13.9 0.4 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal CENP-H PF05837.7 KRH95233.1 - 0.039 14.1 1.1 0.059 13.5 0.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF3158 PF11358.3 KRH95233.1 - 0.087 12.3 0.5 0.098 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Pcc1 PF09341.5 KRH95233.1 - 0.1 12.6 0.1 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Pcc1 Fib_alpha PF08702.5 KRH95233.1 - 0.48 10.5 4.8 0.76 9.8 3.3 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-RING_2 PF13639.1 KRH95235.1 - 2e-13 49.9 9.5 3.8e-13 49.0 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KRH95235.1 - 8.5e-10 38.6 5.1 1.9e-09 37.4 3.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KRH95235.1 - 1.1e-08 34.9 10.9 1.1e-08 34.9 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KRH95235.1 - 6.2e-08 32.1 6.5 1.2e-07 31.3 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KRH95235.1 - 6.1e-07 29.0 8.9 6.1e-07 29.0 6.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KRH95235.1 - 3.5e-05 23.3 11.0 3.5e-05 23.3 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KRH95235.1 - 9.7e-05 22.1 2.6 0.00022 20.9 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 KRH95235.1 - 0.014 15.2 4.1 0.028 14.2 2.9 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 KRH95235.1 - 0.027 14.5 9.8 0.027 14.5 6.8 1.8 2 0 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 KRH95235.1 - 0.35 10.4 7.8 0.87 9.2 5.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KRH95235.1 - 0.66 9.9 9.6 3.3 7.7 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KRH95235.1 - 0.79 9.4 10.9 0.045 13.4 2.1 2.5 2 1 1 3 3 3 0 RING-type zinc-finger PHD PF00628.24 KRH95235.1 - 0.87 9.3 8.3 2 8.1 5.8 1.6 1 0 0 1 1 1 0 PHD-finger vMSA PF00695.14 KRH95235.1 - 2 7.5 7.7 0.038 13.2 0.5 1.6 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Prok-RING_1 PF14446.1 KRH95235.1 - 4.4 7.0 10.1 0.38 10.5 1.6 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 KRH95236.1 - 1.7e-11 43.7 5.9 2.5e-11 43.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KRH95236.1 - 8.7e-09 34.9 7.7 1.3e-08 34.4 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KRH95236.1 - 4.9e-08 32.5 3.5 6.8e-08 32.0 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KRH95236.1 - 6.6e-08 32.4 6.7 9.3e-08 31.9 4.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KRH95236.1 - 9.5e-06 25.1 7.0 9.5e-06 25.1 4.9 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KRH95236.1 - 1.5e-05 24.9 4.1 2.3e-05 24.4 2.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger PHD PF00628.24 KRH95236.1 - 0.0017 17.9 7.4 0.0017 17.9 5.1 1.6 1 1 0 1 1 1 1 PHD-finger zf-RING_4 PF14570.1 KRH95236.1 - 0.0043 16.5 7.9 0.0079 15.7 5.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4206 PF13901.1 KRH95236.1 - 0.0047 16.4 5.1 0.0056 16.2 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) zf-Apc11 PF12861.2 KRH95236.1 - 0.014 15.1 6.2 0.059 13.2 4.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 KRH95236.1 - 0.074 12.2 1.5 0.084 12.0 1.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_1 PF14446.1 KRH95236.1 - 0.077 12.7 6.4 0.1 12.3 1.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 KRH95236.1 - 0.36 10.4 4.2 0.53 9.8 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2296 PF10058.4 KRH95236.1 - 0.39 10.5 7.4 0.81 9.4 5.2 1.6 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-P11 PF03854.9 KRH95236.1 - 0.87 9.1 9.6 1.2 8.7 5.8 1.8 1 1 1 2 2 2 0 P-11 zinc finger Rubredoxin PF00301.15 KRH95236.1 - 2.8 7.8 6.2 16 5.4 1.0 2.6 2 1 0 2 2 2 0 Rubredoxin JmjN PF02375.12 KRH95239.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 jmjN domain JAB PF01398.16 KRH95241.1 - 8.7e-21 73.8 0.0 1.5e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KRH95241.1 - 0.026 14.6 3.4 0.032 14.3 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Tfb2 PF03849.9 KRH95242.1 - 6.3e-28 97.4 5.2 2.7e-17 62.4 0.1 2.1 2 0 0 2 2 2 2 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KRH95242.1 - 0.0047 16.6 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Eaf7 PF07904.8 KRH95243.1 - 0.013 15.4 0.2 0.031 14.2 0.1 1.6 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 EF-hand_8 PF13833.1 KRH95244.1 - 0.09 12.4 0.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair TFIID-18kDa PF02269.11 KRH95245.1 - 6.1e-21 74.0 0.2 2.3e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AKNA PF12443.3 KRH95246.1 - 0.038 14.0 2.2 0.1 12.6 0.0 2.4 2 1 1 3 3 3 0 AT-hook-containing transcription factor SporV_AA PF12164.3 KRH95246.1 - 0.057 13.4 4.3 2.6 8.0 0.3 2.8 2 1 1 3 3 3 0 Stage V sporulation protein AA Syntaxin PF00804.20 KRH95246.1 - 0.076 13.1 11.2 0.79 9.9 0.1 2.2 2 0 0 2 2 2 0 Syntaxin DUF2408 PF10303.4 KRH95246.1 - 0.1 12.7 5.8 1.3 9.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Cobalamin_bind PF01122.14 KRH95246.1 - 0.17 10.4 1.8 1.2 7.6 1.3 2.1 1 1 0 1 1 1 0 Eukaryotic cobalamin-binding protein Histone_HNS PF00816.16 KRH95246.1 - 0.43 11.1 4.1 0.84 10.1 0.5 2.4 2 1 0 2 2 2 0 H-NS histone family BSMAP PF12280.3 KRH95246.1 - 4.4 7.1 6.1 2.2 8.1 1.8 1.8 2 0 0 2 2 2 0 Brain specific membrane anchored protein Lactamase_B_2 PF12706.2 KRH95247.1 - 5.8e-09 35.7 0.0 7.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KRH95247.1 - 0.1 12.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Brix PF04427.13 KRH95248.1 - 3e-23 82.4 4.2 4.5e-23 81.9 2.9 1.3 1 0 0 1 1 1 1 Brix domain YaaC PF14175.1 KRH95248.1 - 0.0096 14.9 1.7 0.014 14.3 1.2 1.2 1 0 0 1 1 1 1 YaaC-like Protein ADIP PF11559.3 KRH95249.1 - 0.021 14.7 4.8 0.021 14.7 3.3 4.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 KRH95249.1 - 0.031 14.7 13.6 0.05 14.0 0.3 3.8 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DNA_photolyase PF00875.13 KRH95249.1 - 0.076 12.7 4.6 0.032 13.9 1.2 1.8 2 0 0 2 2 2 0 DNA photolyase Pox_A_type_inc PF04508.7 KRH95249.1 - 0.32 10.8 7.7 2.3 8.2 1.3 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TSC22 PF01166.13 KRH95249.1 - 1.7 8.6 22.0 0.35 10.8 0.8 4.5 3 2 1 5 5 5 0 TSC-22/dip/bun family PEP-utilisers_N PF05524.8 KRH95249.1 - 2.4 7.9 8.3 2.1 8.1 0.8 3.1 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal SlyX PF04102.7 KRH95249.1 - 4.6 7.6 15.5 0.87 10.0 1.5 3.8 2 1 1 3 3 3 0 SlyX Myb_DNA-binding PF00249.26 KRH95250.1 - 1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L18ae PF01775.12 KRH95250.1 - 0.02 14.7 0.0 1.9 8.4 0.2 2.8 3 1 0 3 3 3 0 Ribosomal L18ae/LX protein domain Ribosomal_S2 PF00318.15 KRH95252.1 - 3.2e-29 101.6 0.1 2.3e-14 53.1 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 Glycos_transf_1 PF00534.15 KRH95253.1 - 6.5e-16 58.2 0.1 2.1e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KRH95253.1 - 2e-06 27.9 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KRH95253.1 - 0.027 14.7 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Gag_spuma PF03276.9 KRH95255.1 - 0.19 10.0 6.4 0.22 9.7 4.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DNA_pol_B PF00136.16 KRH95256.1 - 4e-121 405.0 9.9 4e-121 405.0 6.9 1.9 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KRH95256.1 - 1.3e-46 159.0 24.9 9e-46 156.2 13.5 3.7 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KRH95256.1 - 4.5e-13 48.9 13.6 4.5e-13 48.9 9.4 2.6 2 1 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Helicase_C PF00271.26 KRH95257.1 - 4.2e-10 39.3 0.1 6.6e-09 35.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KRH95257.1 - 1.8e-08 34.1 0.1 6.9e-08 32.3 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KRH95257.1 - 1e-07 31.6 1.7 1.8e-07 30.7 0.1 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 KRH95257.1 - 2.4e-05 24.3 2.8 2.4e-05 24.3 1.9 3.5 2 2 0 2 2 2 1 Helicase associated domain (HA2) Helicase_RecD PF05127.9 KRH95257.1 - 0.00098 18.8 1.3 0.031 13.8 0.0 3.1 3 0 0 3 3 3 1 Helicase T2SE PF00437.15 KRH95257.1 - 0.0012 17.8 0.2 0.0046 15.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 KRH95257.1 - 0.0051 16.9 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KRH95257.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Clr2 PF10383.4 KRH95258.1 - 0.0049 16.8 1.2 0.0049 16.8 0.8 1.9 1 1 0 2 2 2 1 Transcription-silencing protein Clr2 zf-DHHC PF01529.15 KRH95259.1 - 2.2e-25 89.0 40.6 2.7e-25 88.7 21.4 3.7 2 1 0 2 2 2 2 DHHC palmitoyltransferase DUF940 PF06082.6 KRH95259.1 - 4.7 5.6 22.6 6.6 5.1 15.7 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) zf-DHHC PF01529.15 KRH95261.1 - 2.4e-29 101.9 18.4 2.4e-29 101.9 12.7 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase tRNA-synt_2 PF00152.15 KRH95264.1 - 5.2e-92 308.1 0.1 5.2e-92 308.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KRH95264.1 - 1.2e-11 44.2 0.1 2.4e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KRH95264.1 - 4.8e-10 39.0 0.9 3e-06 26.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KRH95264.1 - 0.054 13.0 0.3 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Phage_term_sma PF07141.6 KRH95265.1 - 0.0094 15.5 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Putative bacteriophage terminase small subunit zf-AN1 PF01428.11 KRH95266.1 - 4.2e-07 29.7 14.4 7.3e-07 28.9 10.0 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF1951 PF09188.5 KRH95266.1 - 0.028 14.3 2.2 0.033 14.1 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) Yippee-Mis18 PF03226.9 KRH95266.1 - 0.23 11.5 7.9 0.56 10.2 5.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L10 PF00466.15 KRH95267.1 - 3.4e-17 62.1 2.3 6.4e-17 61.3 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 FlhD PF05247.8 KRH95267.1 - 0.025 14.5 0.1 0.15 12.1 0.0 2.1 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhD) Glyco_hydro_97 PF10566.4 KRH95267.1 - 0.071 12.2 0.2 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 DUF2721 PF11026.3 KRH95270.1 - 0.00059 19.4 0.1 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF244 PF03112.9 KRH95270.1 - 0.028 13.9 0.7 0.032 13.7 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF KNOX2 PF03791.8 KRH95270.1 - 0.044 13.0 0.2 0.06 12.6 0.1 1.1 1 0 0 1 1 1 0 KNOX2 domain Peptidase_C50 PF03568.12 KRH95271.1 - 8.3e-15 54.3 17.6 2.5e-11 42.9 0.1 4.1 2 2 2 4 4 4 3 Peptidase family C50 TPR_7 PF13176.1 KRH95271.1 - 0.069 12.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ssl1 PF04056.9 KRH95272.1 - 2.1e-20 73.1 0.1 2.9e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like Proteasome PF00227.21 KRH95273.1 - 8.8e-21 74.0 0.1 1.2e-20 73.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit UBN_AB PF14075.1 KRH95273.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain HrpB4 PF09502.5 KRH95273.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) V-ATPase_H_C PF11698.3 KRH95274.1 - 0.17 11.8 3.8 0.87 9.5 0.8 2.8 2 1 1 3 3 3 0 V-ATPase subunit H CHD5 PF04420.9 KRH95274.1 - 1.2 8.8 6.8 1.6 8.3 0.4 2.2 2 0 0 2 2 2 0 CHD5-like protein Sld5 PF05916.6 KRH95275.1 - 6.1e-05 23.2 0.5 8.8e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein DPM3 PF08285.6 KRH95275.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4201 PF13870.1 KRH95277.1 - 0.0023 17.4 13.2 0.003 17.0 9.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Med9 PF07544.8 KRH95277.1 - 0.0052 16.5 5.6 0.46 10.2 0.4 2.3 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Streptin-Immun PF11083.3 KRH95277.1 - 0.0093 15.9 6.3 0.041 13.8 1.1 2.2 1 1 1 2 2 2 1 Lantibiotic streptin immunity protein SlyX PF04102.7 KRH95277.1 - 0.04 14.2 10.7 0.11 12.8 2.4 2.3 1 1 0 2 2 2 0 SlyX Fib_alpha PF08702.5 KRH95277.1 - 0.05 13.7 11.7 0.69 10.0 1.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Toxin_51 PF15531.1 KRH95277.1 - 0.052 13.3 0.1 0.097 12.4 0.0 1.4 1 1 0 1 1 1 0 Putative toxin 51 Ada3 PF10198.4 KRH95277.1 - 0.054 13.2 7.6 0.072 12.8 5.3 1.2 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF2407 PF10302.4 KRH95277.1 - 0.1 12.7 0.9 0.12 12.5 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Atg14 PF10186.4 KRH95277.1 - 0.11 11.4 9.1 0.14 11.0 6.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KRH95277.1 - 0.12 10.2 11.5 0.13 10.0 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATC_hydrolase PF14196.1 KRH95277.1 - 0.15 12.4 1.6 0.18 12.2 1.1 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF2968 PF11180.3 KRH95277.1 - 0.15 11.3 5.4 0.19 11.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF948 PF06103.6 KRH95277.1 - 0.18 11.6 3.7 6.2 6.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KRH95277.1 - 0.19 10.8 2.5 0.31 10.1 1.7 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KRH95277.1 - 0.25 11.1 9.1 49 3.7 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Sec2p PF06428.6 KRH95277.1 - 0.26 11.1 13.2 0.5 10.2 1.6 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DivIC PF04977.10 KRH95277.1 - 0.36 10.3 8.6 2.3 7.7 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator MtrG PF04210.8 KRH95277.1 - 0.46 10.1 2.2 0.36 10.5 0.3 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G TMF_DNA_bd PF12329.3 KRH95277.1 - 0.68 9.7 13.5 2.1 8.2 1.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.6 KRH95277.1 - 0.83 7.1 7.9 0.95 6.9 5.5 1.1 1 0 0 1 1 1 0 Prominin Viral_P18 PF04521.8 KRH95277.1 - 0.97 8.8 7.5 4.1 6.8 1.2 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein GrpE PF01025.14 KRH95277.1 - 1.1 8.7 12.3 0.67 9.4 6.4 1.8 1 1 1 2 2 2 0 GrpE GvpK PF05121.7 KRH95277.1 - 1.1 9.0 6.4 5.4 6.9 1.6 2.4 1 1 1 2 2 2 0 Gas vesicle protein K Allexi_40kDa PF05549.6 KRH95277.1 - 1.3 8.2 8.9 3.9 6.6 6.2 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein FlaC_arch PF05377.6 KRH95277.1 - 1.3 8.9 7.7 3.2 7.7 0.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.1 KRH95277.1 - 1.4 9.2 9.1 0.42 10.9 1.2 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF4140 PF13600.1 KRH95277.1 - 1.4 9.4 5.2 16 5.9 0.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 KRH95277.1 - 1.5 8.8 7.0 3.8 7.5 4.5 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF641 PF04859.7 KRH95277.1 - 1.7 8.4 10.3 5.7 6.7 0.9 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF342 PF03961.8 KRH95277.1 - 1.9 6.7 9.3 2.3 6.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 KRH95277.1 - 2.1 8.6 11.0 1.1 9.5 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3847 PF12958.2 KRH95277.1 - 2.7 7.8 7.9 11 5.9 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) APG6 PF04111.7 KRH95277.1 - 3.9 6.4 13.7 4.6 6.1 9.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 KRH95277.1 - 4.4 6.9 11.4 13 5.4 4.2 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.11 KRH95277.1 - 5.8 7.1 11.7 11 6.3 8.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 ALMT PF11744.3 KRH95277.1 - 6.6 5.2 8.4 33 2.9 5.8 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF2951 PF11166.3 KRH95277.1 - 7.7 6.4 15.4 1.3 8.9 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) NPV_P10 PF05531.7 KRH95279.1 - 0.0006 20.0 0.6 0.0058 16.8 0.1 2.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein BDV_P24 PF06595.6 KRH95279.1 - 0.00065 19.5 1.7 0.00084 19.1 1.2 1.3 1 1 0 1 1 1 1 Borna disease virus P24 protein DUF1664 PF07889.7 KRH95279.1 - 0.00067 19.4 3.0 0.00099 18.9 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) BAR_3_WASP_bdg PF10456.4 KRH95279.1 - 0.0029 16.8 0.3 0.0041 16.3 0.2 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BLOC1_2 PF10046.4 KRH95279.1 - 0.0043 17.1 5.7 0.032 14.3 3.8 2.0 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.1 KRH95279.1 - 0.0069 16.4 4.4 0.0089 16.0 3.1 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit RasGAP_C PF03836.10 KRH95279.1 - 0.0079 15.8 3.0 0.0086 15.7 2.1 1.2 1 0 0 1 1 1 1 RasGAP C-terminus DHC_N1 PF08385.7 KRH95279.1 - 0.01 14.2 2.9 0.011 14.1 2.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF948 PF06103.6 KRH95279.1 - 0.011 15.5 1.6 1.6 8.6 0.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1395 PF07160.7 KRH95279.1 - 0.017 14.6 3.1 1.7 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) DUF342 PF03961.8 KRH95279.1 - 0.036 12.4 7.7 0.042 12.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NLE PF08154.7 KRH95279.1 - 0.04 13.9 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 NLE (NUC135) domain YPEB PF14620.1 KRH95279.1 - 0.056 12.4 4.2 0.064 12.2 2.9 1.1 1 0 0 1 1 1 0 YpeB sporulation IDO PF01231.13 KRH95279.1 - 0.059 11.8 0.8 0.088 11.2 0.4 1.4 1 1 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF4546 PF15079.1 KRH95279.1 - 0.062 12.4 3.0 0.093 11.8 2.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4546) DASH_Duo1 PF08651.5 KRH95279.1 - 0.071 12.6 2.3 0.15 11.6 0.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 T2SF PF00482.18 KRH95279.1 - 0.072 12.9 0.2 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F CorA PF01544.13 KRH95279.1 - 0.084 11.8 1.5 0.1 11.6 1.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Allexi_40kDa PF05549.6 KRH95279.1 - 0.099 11.9 3.0 0.12 11.6 2.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.19 KRH95279.1 - 0.11 12.1 4.4 0.14 11.8 3.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 KRH95279.1 - 0.11 12.0 7.5 0.13 11.8 5.2 1.1 1 0 0 1 1 1 0 IncA protein DUF16 PF01519.11 KRH95279.1 - 0.12 12.6 4.2 0.21 11.8 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Complex1_LYR_2 PF13233.1 KRH95279.1 - 0.12 12.8 1.5 0.14 12.6 1.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DUF3708 PF12501.3 KRH95279.1 - 0.16 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF4239 PF14023.1 KRH95279.1 - 0.16 11.2 0.8 0.2 10.9 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) COG5 PF10392.4 KRH95279.1 - 0.17 11.8 3.2 0.2 11.6 1.2 1.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 PspB PF06667.7 KRH95279.1 - 0.23 11.4 2.2 3.7 7.5 1.4 2.5 1 1 0 1 1 1 0 Phage shock protein B Snapin_Pallidin PF14712.1 KRH95279.1 - 0.24 11.7 5.5 1.4 9.2 1.2 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Fmp27_WPPW PF10359.4 KRH95279.1 - 0.28 9.5 7.0 0.31 9.3 4.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 KRH95279.1 - 0.32 8.7 7.3 0.35 8.6 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vip3A_N PF12495.3 KRH95279.1 - 0.35 10.5 2.4 0.9 9.1 1.6 1.5 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Rho_Binding PF08912.6 KRH95279.1 - 0.43 10.9 8.7 0.1 12.8 1.9 2.3 1 1 0 2 2 2 0 Rho Binding DUF2951 PF11166.3 KRH95279.1 - 0.47 10.3 5.9 0.56 10.0 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) UPF0184 PF03670.8 KRH95279.1 - 0.47 10.6 5.8 1.3 9.2 2.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Sec20 PF03908.8 KRH95279.1 - 0.55 9.9 3.6 0.8 9.4 1.4 1.8 1 1 1 2 2 2 0 Sec20 Fib_alpha PF08702.5 KRH95279.1 - 0.77 9.8 5.3 0.45 10.6 1.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 KRH95279.1 - 0.97 9.7 6.9 1.4 9.2 4.5 1.5 1 1 0 1 1 1 0 Spectrin repeat Fijivirus_P9-2 PF06837.6 KRH95279.1 - 1.3 8.1 3.4 1.3 8.1 0.1 2.0 1 1 1 2 2 2 0 Fijivirus P9-2 protein DUF972 PF06156.8 KRH95279.1 - 1.6 9.1 8.7 7.3 6.9 6.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) zf-C4H2 PF10146.4 KRH95279.1 - 5.3 6.9 10.0 5.9 6.8 6.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Apc3 PF12895.2 KRH95280.1 - 3.1e-05 24.0 10.8 0.00026 21.0 5.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KRH95280.1 - 5.2e-05 23.5 1.1 0.0099 16.2 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KRH95280.1 - 0.00021 20.9 3.3 0.52 10.3 0.6 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KRH95280.1 - 0.0091 15.5 6.3 0.91 9.2 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KRH95280.1 - 0.016 14.9 5.7 0.044 13.5 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KRH95280.1 - 0.023 14.3 1.6 0.13 11.9 1.1 2.2 1 1 1 2 2 2 0 TPR repeat TPR_12 PF13424.1 KRH95280.1 - 0.028 14.3 1.5 0.65 9.9 0.8 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KRH95280.1 - 0.078 13.6 0.2 0.36 11.5 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 KRH95280.1 - 1.9 8.3 6.8 14 5.6 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.6 KRH95281.1 - 2.2e-108 362.4 10.6 8.6e-54 182.6 3.6 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KRH95281.1 - 4.4e-08 31.6 0.4 0.0013 16.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KRH95281.1 - 0.014 15.1 0.6 0.077 12.7 0.1 2.4 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Laminin_EGF PF00053.19 KRH95281.1 - 3.1 7.8 8.0 8.9 6.3 5.6 1.8 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) ACDC PF14733.1 KRH95282.1 - 6.8 6.8 12.3 0.4 10.8 2.4 3.1 1 1 1 2 2 2 0 AP2-coincident C-terminal Amidase PF01425.16 KRH95283.1 - 0.1 11.4 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Amidase TrmB PF01978.14 KRH95283.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF1896 PF08989.5 KRH95284.1 - 0.028 14.2 0.2 0.03 14.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) FKS1_dom1 PF14288.1 KRH95284.1 - 0.11 12.4 0.4 0.12 12.2 0.3 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2762 PF10960.3 KRH95285.1 - 0.42 10.3 6.0 0.15 11.7 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) Beta_protein PF14350.1 KRH95287.1 - 0.042 13.0 0.3 0.078 12.1 0.2 1.4 1 0 0 1 1 1 0 Beta protein Tbf5 PF06331.7 KRH95289.1 - 2.3e-07 30.5 0.1 2.8e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 zf-C2H2_jaz PF12171.3 KRH95290.1 - 0.0017 18.4 1.4 0.0017 18.4 0.9 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KRH95290.1 - 0.0036 17.3 3.0 0.009 16.1 2.1 1.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KRH95290.1 - 0.0049 17.1 1.0 0.0049 17.1 0.7 2.3 2 1 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 KRH95290.1 - 0.008 15.9 0.2 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger zf-C2HC_2 PF13913.1 KRH95290.1 - 0.016 14.8 0.2 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 KRH95290.1 - 0.053 12.9 0.1 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.21 KRH95290.1 - 0.085 13.2 1.4 0.085 13.2 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.2 KRH95290.1 - 6.5 7.1 9.9 0.64 10.3 0.6 2.9 2 1 0 2 2 2 0 Zinc-finger of C2H2 type ATP-synt_C PF00137.16 KRH95291.1 - 1.4e-07 31.2 1.0 1.4e-07 31.2 0.7 2.2 2 0 0 2 2 2 1 ATP synthase subunit C DUF2975 PF11188.3 KRH95291.1 - 0.54 9.9 6.3 0.79 9.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF155 PF02582.9 KRH95293.1 - 1.3e-46 158.7 0.8 2.3e-46 157.8 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 eIF-5_eIF-2B PF01873.12 KRH95294.1 - 3.2e-21 75.2 0.8 6.7e-21 74.2 0.1 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Peptidase_C65 PF10275.4 KRH95296.1 - 7.5e-12 45.1 8.8 2.4e-10 40.1 6.1 2.5 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KRH95296.1 - 0.0017 18.9 1.0 0.43 11.1 1.1 2.3 1 1 1 2 2 2 2 OTU-like cysteine protease Uso1_p115_C PF04871.8 KRH95299.1 - 7 6.5 6.4 4.8 7.1 0.9 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DcpS_C PF11969.3 KRH95300.1 - 1.4e-13 51.1 1.3 1.4e-13 51.1 0.9 1.9 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Herpes_BLLF1 PF05109.8 KRH95300.1 - 2.4e-05 22.5 18.2 3e-05 22.2 12.6 1.1 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) HAUS6_N PF14661.1 KRH95300.1 - 0.42 9.9 3.9 0.79 9.0 2.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF948 PF06103.6 KRH95300.1 - 1.1 9.1 15.5 0.48 10.3 5.3 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF506 PF04720.7 KRH95300.1 - 3.1 7.3 6.6 5.8 6.4 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DcpS PF05652.7 KRH95300.1 - 3.3 8.1 19.7 4.2e+02 1.3 13.6 3.3 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF2683 PF10884.3 KRH95300.1 - 3.4 7.6 7.1 0.28 11.1 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2683) Dopey_N PF04118.9 KRH95301.1 - 1.1e-33 116.2 3.5 1.1e-33 116.2 2.4 4.8 5 1 0 5 5 5 2 Dopey, N-terminal YadA_head PF05658.9 KRH95301.1 - 0.19 12.0 0.8 0.42 10.9 0.6 1.5 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin RNA_pol_Rpb1_5 PF04998.12 KRH95302.1 - 6.4 5.9 0.0 6.4 5.9 0.0 6.4 2 2 2 4 4 4 0 RNA polymerase Rpb1, domain 5 PK PF00224.16 KRH95303.1 - 1.3e-98 329.8 13.0 3.9e-51 173.6 0.1 2.3 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 KRH95303.1 - 1.1e-05 24.4 0.1 6.2e-05 21.9 0.1 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CPSase_L_D3 PF02787.14 KRH95303.1 - 0.017 14.9 2.6 0.72 9.6 0.1 3.4 2 1 1 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Death PF00531.17 KRH95303.1 - 0.037 13.8 1.7 3.4 7.5 0.1 2.7 1 1 0 2 2 2 0 Death domain DUF2336 PF10098.4 KRH95303.1 - 0.15 11.2 0.5 0.27 10.4 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) Bac_small_YrzI PF09501.5 KRH95303.1 - 0.19 11.6 10.6 5.6 6.9 0.4 4.5 3 1 1 4 4 4 0 Probable sporulation protein (Bac_small_yrzI) DUF465 PF04325.8 KRH95303.1 - 0.39 10.4 9.8 5 6.9 0.9 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF465) Trypan_PARP PF05887.6 KRH95303.1 - 1.6 8.5 15.8 3.4 7.4 11.0 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Laminin_B PF00052.13 KRH95305.1 - 0.051 13.1 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Laminin B (Domain IV) Ribosomal_L37e PF01907.14 KRH95306.1 - 4.9e-19 67.8 14.0 7.4e-19 67.2 9.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KRH95306.1 - 0.008 15.9 3.4 0.013 15.3 2.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_5 PF14634.1 KRH95306.1 - 0.058 13.1 4.2 0.094 12.4 2.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain DUF2387 PF09526.5 KRH95306.1 - 0.12 12.3 5.7 1.3 9.0 0.9 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) GFA PF04828.9 KRH95306.1 - 0.13 12.2 3.8 0.19 11.7 2.5 1.5 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme ASFV_p27 PF06556.6 KRH95306.1 - 0.23 11.3 3.7 0.13 12.1 1.4 1.4 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus zf-C3HC4 PF00097.20 KRH95306.1 - 0.34 10.6 7.0 0.59 9.8 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FUR PF01475.14 KRH95306.1 - 0.52 10.2 3.4 0.49 10.3 1.4 1.7 1 1 1 2 2 2 0 Ferric uptake regulator family zf-C3HC4_2 PF13923.1 KRH95306.1 - 0.65 10.0 5.3 1.1 9.3 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 KRH95306.1 - 2 7.7 5.4 1.1 8.5 0.3 1.9 1 1 1 2 2 2 0 zinc-ribbon domain DUF1258 PF06869.7 KRH95306.1 - 2 7.4 11.8 0.86 8.6 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zinc_ribbon_2 PF13240.1 KRH95306.1 - 4.4 6.9 5.8 0.39 10.2 0.7 1.7 2 0 0 2 2 2 0 zinc-ribbon domain HAD_2 PF13419.1 KRH95307.1 - 0.03 14.5 0.2 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4131 PF13567.1 KRH95309.1 - 0.36 10.2 2.7 0.44 9.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TRP PF06011.7 KRH95309.1 - 0.37 9.3 9.1 0.42 9.1 6.3 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel G3P_acyltransf PF02660.10 KRH95309.1 - 0.41 10.1 6.8 0.51 9.8 4.7 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase DUF2101 PF09874.4 KRH95309.1 - 1.1 8.7 8.2 1.4 8.3 5.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Choline_kin_N PF04428.9 KRH95310.1 - 0.2 11.1 0.8 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 Choline kinase N terminus AAA_18 PF13238.1 KRH95311.1 - 1.6e-13 51.0 0.3 1.6e-13 51.0 0.2 2.2 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 KRH95311.1 - 8.6e-12 45.9 0.3 1.8e-11 44.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KRH95311.1 - 8.9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KRH95311.1 - 1.7e-05 23.9 0.5 2.7e-05 23.3 0.4 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KRH95311.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KRH95311.1 - 0.00019 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KRH95311.1 - 0.00043 19.2 0.6 0.00067 18.6 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 KRH95311.1 - 0.00083 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 KRH95311.1 - 0.00097 18.4 0.1 0.0026 17.0 0.0 1.8 1 1 1 2 2 2 1 PhoH-like protein KTI12 PF08433.5 KRH95311.1 - 0.0015 17.7 1.5 0.0025 17.0 0.0 1.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.4 KRH95311.1 - 0.0015 17.5 0.1 0.0015 17.5 0.1 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KRH95311.1 - 0.0025 17.7 1.9 0.0031 17.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KRH95311.1 - 0.0026 17.8 0.0 0.0061 16.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KRH95311.1 - 0.0027 17.3 0.6 0.0027 17.3 0.4 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KRH95311.1 - 0.0034 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KRH95311.1 - 0.0041 16.8 0.2 0.0041 16.8 0.2 1.8 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.1 KRH95311.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KRH95311.1 - 0.0056 16.8 0.5 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 KRH95311.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KRH95311.1 - 0.011 15.2 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 KRH95311.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SKI PF01202.17 KRH95311.1 - 0.013 15.3 3.1 0.032 14.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate kinase NACHT PF05729.7 KRH95311.1 - 0.015 14.9 0.1 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 KRH95311.1 - 0.017 14.6 0.1 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 KRH95311.1 - 0.023 14.3 0.6 0.056 13.0 0.1 2.0 2 1 0 2 2 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 KRH95311.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KRH95311.1 - 0.026 14.4 0.5 0.064 13.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 KRH95311.1 - 0.028 13.5 0.7 0.028 13.5 0.5 2.0 2 2 0 2 2 2 0 KaiC AAA_29 PF13555.1 KRH95311.1 - 0.033 13.7 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.10 KRH95311.1 - 0.033 13.2 0.1 0.033 13.2 0.1 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase Cytidylate_kin2 PF13189.1 KRH95311.1 - 0.034 14.0 0.0 0.034 14.0 0.0 2.2 3 0 0 3 3 3 0 Cytidylate kinase-like family AAA_3 PF07726.6 KRH95311.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 KRH95311.1 - 0.065 11.9 10.1 0.02 13.5 5.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_11 PF13086.1 KRH95311.1 - 0.076 12.5 0.2 0.076 12.5 0.1 2.2 1 1 1 2 2 1 0 AAA domain TrwB_AAD_bind PF10412.4 KRH95311.1 - 0.11 11.0 1.2 0.14 10.7 0.4 1.4 1 1 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 KRH95311.1 - 0.12 11.5 0.3 0.23 10.5 0.2 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KRH95311.1 - 0.21 10.3 3.2 0.12 11.1 0.5 1.9 2 1 1 3 3 3 0 ArgK protein Viral_helicase1 PF01443.13 KRH95311.1 - 0.25 10.8 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.18 KRH95311.1 - 0.44 9.9 5.6 0.2 11.0 1.7 2.0 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Herpes_PAP PF03325.8 KRH95311.1 - 1.1 8.7 7.4 2.5 7.5 5.1 1.7 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Macoilin PF09726.4 KRH95311.1 - 3.7 5.7 10.1 4.8 5.3 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Thymidylate_kin PF02223.12 KRH95311.1 - 4.7 6.5 7.8 2.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Thymidylate kinase PRK PF00485.13 KRH95311.1 - 5.9 6.3 7.5 10 5.6 0.1 3.0 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family Lectin_leg-like PF03388.8 KRH95317.1 - 0.0015 17.6 0.1 0.0028 16.8 0.1 1.4 1 0 0 1 1 1 1 Legume-like lectin family ERCC4 PF02732.10 KRH95318.1 - 9.7e-15 54.5 1.2 1.4e-13 50.8 0.2 3.0 2 0 0 2 2 2 1 ERCC4 domain Kinesin PF00225.18 KRH95319.1 - 2.7e-70 236.7 7.9 2.7e-70 236.7 5.5 3.0 2 2 0 2 2 2 1 Kinesin motor domain DUF3132 PF11330.3 KRH95319.1 - 0.019 14.7 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) KCl_Cotrans_1 PF03522.10 KRH95319.1 - 1.1 8.8 4.3 1.1 8.8 1.6 2.1 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) FtsK_SpoIIIE PF01580.13 KRH95319.1 - 4.2 6.7 5.7 18 4.7 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family ApoO PF09769.4 KRH95319.1 - 9.4 5.9 11.3 0.89 9.2 3.4 2.4 1 1 1 2 2 2 0 Apolipoprotein O EF-hand_6 PF13405.1 KRH95320.1 - 0.08 12.8 1.1 1.9 8.5 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain DUF643 PF04867.7 KRH95320.1 - 0.27 11.6 5.6 3 8.2 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF643) RNA_pol_N PF01194.12 KRH95322.1 - 3.3e-24 84.6 2.8 3.8e-24 84.4 1.9 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF2688 PF10892.3 KRH95322.1 - 0.012 15.3 0.7 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) CamS PF07537.6 KRH95322.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor DUF581 PF04570.9 KRH95322.1 - 1.2 8.5 4.5 0.41 9.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF581) DCP2 PF05026.8 KRH95324.1 - 1.4e-08 34.4 1.4 1.4e-08 34.4 1.0 2.2 3 0 0 3 3 3 1 Dcp2, box A domain NUDIX PF00293.23 KRH95324.1 - 4.6e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF3895 PF13034.1 KRH95324.1 - 0.18 11.2 2.3 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) Diphthamide_syn PF01866.12 KRH95325.1 - 1.9e-10 40.4 0.3 3e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CS PF04969.11 KRH95325.1 - 0.0059 17.1 1.2 0.24 11.9 0.1 2.7 2 0 0 2 2 2 1 CS domain Glutaredoxin PF00462.19 KRH95327.1 - 0.00011 22.0 0.3 0.00029 20.7 0.1 1.8 2 0 0 2 2 2 1 Glutaredoxin Apolipoprotein PF01442.13 KRH95327.1 - 0.00023 20.7 1.7 0.00056 19.4 1.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Armet PF10208.4 KRH95327.1 - 0.0029 17.2 1.8 0.0061 16.2 1.0 1.7 1 1 0 1 1 1 1 Degradation arginine-rich protein for mis-folding DUF883 PF05957.8 KRH95327.1 - 0.0094 16.3 2.9 0.0099 16.2 0.2 2.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF883) Methyltransf_32 PF13679.1 KRH95327.1 - 1.7 8.3 4.6 49 3.5 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain ArsC PF03960.10 KRH95327.1 - 5.7 7.0 7.0 7.4 6.6 0.1 3.3 3 1 1 4 4 4 0 ArsC family MT0933_antitox PF14013.1 KRH95327.1 - 5.8 7.0 9.4 3e+02 1.6 6.5 3.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein YtxH PF12732.2 KRH95327.1 - 6.3 7.2 18.2 30 5.0 8.1 3.4 1 1 1 2 2 2 0 YtxH-like protein DUF4318 PF14201.1 KRH95328.1 - 0.0041 16.9 4.7 0.7 9.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4318) MIT PF04212.13 KRH95328.1 - 0.0081 16.0 1.3 0.016 15.0 0.9 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Shisa PF13908.1 KRH95328.1 - 0.028 14.5 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-FCS PF06467.9 KRH95328.1 - 0.053 13.1 0.2 0.19 11.3 0.2 2.0 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PPV_E1_N PF00524.13 KRH95328.1 - 0.14 12.3 7.2 1.7 8.8 0.6 2.1 2 0 0 2 2 2 0 E1 Protein, N terminal domain ATG27 PF09451.5 KRH95328.1 - 0.17 11.1 4.4 0.21 10.8 3.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2387 PF09526.5 KRH95328.1 - 0.17 11.8 1.4 5.7 6.9 0.4 2.8 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) NIF3 PF01784.13 KRH95329.1 - 4.3e-43 147.6 0.8 5.3e-43 147.3 0.5 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) UPF0160 PF03690.8 KRH95330.1 - 7.5e-70 235.8 1.8 2.1e-69 234.3 1.2 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) Lipid_bd PF12888.2 KRH95330.1 - 0.074 12.8 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipid-binding putative hydrolase HTH_AraC PF00165.18 KRH95330.1 - 0.086 12.6 1.1 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Sec20 PF03908.8 KRH95331.1 - 3.5e-05 23.4 0.3 8.2e-05 22.2 0.1 1.7 1 1 1 2 2 2 1 Sec20 Synaptobrevin PF00957.16 KRH95331.1 - 0.00023 20.7 2.6 0.00033 20.1 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin SAS4 PF15460.1 KRH95331.1 - 0.14 12.0 4.7 0.49 10.2 3.1 1.9 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 Pox_A_type_inc PF04508.7 KRH95331.1 - 0.31 10.9 0.0 0.31 10.9 0.0 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat TALPID3 PF15324.1 KRH95331.1 - 0.48 7.7 2.4 0.59 7.4 1.7 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF4559 PF15112.1 KRH95331.1 - 0.63 9.1 4.2 0.34 10.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) MtrG PF04210.8 KRH95331.1 - 0.91 9.2 6.0 1.5 8.5 1.0 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G IFN-gamma PF00714.12 KRH95331.1 - 3.5 7.4 7.6 1.3 8.8 0.9 2.7 1 1 2 3 3 3 0 Interferon gamma AAA PF00004.24 KRH95332.1 - 3.3e-42 143.8 0.0 7.3e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KRH95332.1 - 1.5e-06 28.4 0.2 0.00046 20.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KRH95332.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KRH95332.1 - 2.7e-05 23.2 0.0 4.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KRH95332.1 - 7.8e-05 22.4 0.2 0.00043 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KRH95332.1 - 0.00039 19.5 0.0 0.00083 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KRH95332.1 - 0.00072 19.5 0.1 0.0036 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KRH95332.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KRH95332.1 - 0.0026 18.5 0.1 0.0054 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KRH95332.1 - 0.0046 16.1 0.1 0.21 10.6 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.6 KRH95332.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KRH95332.1 - 0.0066 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KRH95332.1 - 0.008 15.9 0.5 0.018 14.7 0.4 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KRH95332.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KRH95332.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 KRH95332.1 - 0.023 13.5 0.0 0.099 11.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 KRH95332.1 - 0.025 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KRH95332.1 - 0.035 12.8 0.0 0.066 11.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 KRH95332.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KRH95332.1 - 0.054 12.8 0.6 1.2 8.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KRH95332.1 - 0.06 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KRH95332.1 - 0.066 12.8 0.2 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KRH95332.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KRH95332.1 - 0.079 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KRH95332.1 - 0.13 11.4 0.3 0.39 9.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Piwi PF02171.12 KRH95333.1 - 0.0084 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Methyltransf_8 PF05148.10 KRH95334.1 - 5.6e-41 140.5 6.5 5.4e-31 107.9 0.1 3.2 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KRH95334.1 - 3.5e-08 33.8 0.0 6.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KRH95334.1 - 5.1e-06 26.1 0.6 9e-06 25.3 0.5 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KRH95334.1 - 0.00016 20.8 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KRH95334.1 - 0.00056 20.4 0.0 0.0016 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KRH95334.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KRH95334.1 - 0.0036 17.7 0.7 0.0078 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Herpes_U15 PF05613.6 KRH95334.1 - 0.004 17.4 0.1 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Human herpesvirus U15 protein MTS PF05175.9 KRH95334.1 - 0.0059 16.0 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KRH95334.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lys PF00062.15 KRH95334.1 - 0.06 13.3 0.6 0.14 12.1 0.1 1.8 1 1 1 2 2 2 0 C-type lysozyme/alpha-lactalbumin family APC10 PF03256.11 KRH95335.1 - 1.4e-20 73.7 0.8 8.8e-20 71.1 0.6 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 KRH95335.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.3 1 1 0 1 1 1 0 F5/8 type C domain Caps_synth PF05704.7 KRH95335.1 - 0.082 12.0 0.1 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PITH PF06201.8 KRH95335.1 - 0.088 12.5 0.1 9.4 5.9 0.0 2.1 1 1 1 2 2 2 0 PITH domain Ribosomal_S5_C PF03719.10 KRH95338.1 - 2.1e-22 78.1 0.0 3.6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KRH95338.1 - 2.9e-19 68.5 2.5 4.5e-19 67.9 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Myb_DNA-bind_6 PF13921.1 KRH95339.1 - 0.0022 18.0 1.1 0.0048 16.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DASH_Dad1 PF08649.5 KRH95339.1 - 0.022 14.4 2.2 0.022 14.4 1.5 3.3 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF4428 PF14471.1 KRH95339.1 - 0.057 13.1 10.8 0.2 11.4 5.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) SNARE PF05739.14 KRH95339.1 - 0.46 10.2 5.9 0.28 10.9 1.8 2.4 2 0 0 2 2 2 0 SNARE domain DUF479 PF04336.7 KRH95339.1 - 1.3 9.2 6.2 11 6.2 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function, DUF479 UPF0184 PF03670.8 KRH95339.1 - 2.7 8.2 13.8 0.079 13.1 3.5 2.7 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) ARID PF01388.16 KRH95341.1 - 1.3e-10 40.9 0.3 1.3e-10 40.9 0.2 3.0 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Chromo PF00385.19 KRH95341.1 - 0.0015 18.1 3.9 0.033 13.8 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain VPS9 PF02204.13 KRH95342.1 - 1.7e-06 28.0 8.9 0.00057 19.8 0.8 4.2 4 0 0 4 4 4 3 Vacuolar sorting protein 9 (VPS9) domain DUF421 PF04239.7 KRH95344.1 - 0.14 11.7 0.1 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF421) SRF-TF PF00319.13 KRH95345.1 - 3e-19 67.9 0.3 4.6e-19 67.3 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.1 KRH95345.1 - 0.08 12.8 1.1 0.18 11.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) WD40 PF00400.27 KRH95346.1 - 1.9e-07 30.7 0.0 3.3e-05 23.5 0.1 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 KRH95347.1 - 0.00069 19.9 0.0 0.0027 18.0 0.0 2.0 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Peptidase_S30 PF01577.11 KRH95347.1 - 0.0083 15.5 1.0 0.012 15.0 0.7 1.2 1 0 0 1 1 1 1 Potyvirus P1 protease Tau95 PF09734.4 KRH95348.1 - 1.7e-13 50.5 9.1 1.8e-12 47.2 6.3 2.2 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit MAP65_ASE1 PF03999.7 KRH95352.1 - 1.2e-10 40.7 9.7 1.2e-10 40.7 6.7 2.7 3 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family)