# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- OxoGdeHyase_C PF16870.5 CBY30336.1 - 0.043 13.5 0.3 0.3 10.8 0.3 2.0 1 1 1 2 2 2 0 2-oxoglutarate dehydrogenase C-terminal CUB PF00431.20 CBY30338.1 - 2.4e-08 34.3 1.1 3.1e-08 33.9 0.8 1.3 1 1 0 1 1 1 1 CUB domain CUB PF00431.20 CBY30339.1 - 1.6e-07 31.6 0.5 8.2e-07 29.4 0.4 1.8 1 1 1 2 2 2 2 CUB domain SYCE1 PF15233.6 CBY30340.1 - 0.0031 17.6 7.4 0.0031 17.6 7.4 2.3 1 1 1 2 2 2 1 Synaptonemal complex central element protein 1 Golgin_A5 PF09787.9 CBY30340.1 - 0.0033 17.0 8.4 0.0033 17.0 8.4 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 CALCOCO1 PF07888.11 CBY30340.1 - 0.022 13.7 12.8 0.026 13.4 12.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LXG PF04740.12 CBY30340.1 - 0.025 14.3 9.4 0.081 12.6 3.9 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily ADIP PF11559.8 CBY30340.1 - 0.026 14.6 14.4 0.62 10.1 7.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CBY30340.1 - 0.038 14.5 10.9 0.061 13.8 10.9 1.4 1 0 0 1 1 1 0 Fez1 PTPlike_phytase PF14566.6 CBY30340.1 - 0.051 13.7 6.7 0.044 13.9 5.1 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate RPW8 PF05659.11 CBY30340.1 - 0.06 13.0 6.0 0.38 10.4 1.1 3.1 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4407 PF14362.6 CBY30340.1 - 0.082 12.3 7.0 0.11 11.9 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY30340.1 - 0.091 12.8 12.5 0.17 12.0 10.4 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 CBY30340.1 - 0.099 13.6 12.1 2.8 8.9 0.5 2.5 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RNA_pol_Rpc4 PF05132.14 CBY30340.1 - 0.22 11.9 1.1 0.29 11.5 1.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 HIP1_clath_bdg PF16515.5 CBY30340.1 - 0.26 11.9 11.2 2.7 8.7 1.8 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 CBY30340.1 - 0.28 11.0 13.3 0.11 12.4 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 CBY30340.1 - 0.28 11.5 6.5 1.6 9.1 1.3 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DASH_Duo1 PF08651.10 CBY30340.1 - 0.38 10.6 5.9 0.7 9.7 0.0 3.2 2 1 0 3 3 3 0 DASH complex subunit Duo1 Lebercilin PF15619.6 CBY30340.1 - 0.53 9.9 16.5 5 6.7 16.5 2.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 CBY30340.1 - 0.54 10.4 17.2 1.1 9.3 7.4 2.9 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CBY30340.1 - 0.55 10.4 14.4 2.6 8.2 7.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 CBY30340.1 - 0.61 10.4 16.1 26 5.1 13.5 3.8 1 1 1 2 2 2 0 Tho complex subunit 7 CC2-LZ PF16516.5 CBY30340.1 - 0.85 10.0 14.0 1.6 9.2 10.1 2.8 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator APG6_N PF17675.1 CBY30340.1 - 1.1 9.8 12.0 1.1 9.7 10.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CBY30340.1 - 1.2 9.9 5.7 6.1 7.5 0.1 3.5 2 1 1 3 3 3 0 SlyX DUF745 PF05335.13 CBY30340.1 - 2.1 8.0 8.5 9.3 5.9 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF5082 PF16888.5 CBY30340.1 - 2.2 8.6 16.0 13 6.1 10.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 CBY30340.1 - 2.5 8.2 12.9 1.1 9.3 4.8 2.6 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.15 CBY30340.1 - 2.9 7.7 13.2 3.4 7.5 0.9 2.9 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 CBY30340.1 - 2.9 8.1 15.6 5.4 7.2 6.9 3.0 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4665 PF15679.5 CBY30340.1 - 3.4 8.4 12.6 6.4 7.5 4.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) BST2 PF16716.5 CBY30340.1 - 3.4 8.3 15.5 47 4.7 7.9 3.2 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 DHR10 PF18595.1 CBY30340.1 - 3.4 7.7 16.5 5 7.2 1.1 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 CBY30340.1 - 3.6 7.9 11.4 2.2 8.5 0.3 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4164 PF13747.6 CBY30340.1 - 4.4 7.6 13.5 1.7 8.9 4.4 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 CBY30340.1 - 5.2 4.9 13.0 0.61 7.9 0.5 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CBY30340.1 - 6 6.0 9.8 8 5.6 7.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein Myosin_head PF00063.21 CBY30341.1 - 5.2e-259 861.1 0.4 9.5e-259 860.2 0.4 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CBY30341.1 - 1.1e-23 83.5 7.2 1.1e-23 83.5 3.8 2.9 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CBY30341.1 - 9.7e-12 43.6 29.7 8.2e-06 25.2 0.5 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY30341.1 - 0.016 15.5 3.4 0.02 15.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CBY30341.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.6 3 1 0 4 4 4 0 AAA ATPase domain RNA_POL_M_15KD PF02150.16 CBY30344.1 - 5.2e-10 39.0 8.0 5.2e-10 39.0 8.0 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CBY30344.1 - 0.00049 19.9 11.6 0.00049 19.9 11.6 3.9 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 CBY30344.1 - 0.00079 19.9 1.8 0.00079 19.9 1.8 2.3 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 CBY30344.1 - 0.035 14.1 5.2 0.035 14.1 5.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 CBY30344.1 - 0.15 12.1 10.9 0.063 13.3 3.7 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CpXC PF14353.6 CBY30344.1 - 1.6 8.8 12.0 0.36 10.9 1.4 2.5 1 1 0 2 2 2 0 CpXC protein Lar_restr_allev PF14354.6 CBY30344.1 - 1.9 8.9 16.7 0.086 13.2 4.0 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_10 PF10058.9 CBY30344.1 - 3.6 7.4 14.6 0.27 11.0 2.7 3.0 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein KfrA_N PF11740.8 CBY30345.1 - 0.0034 18.0 0.0 0.0051 17.5 0.0 1.3 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term WBP-1 PF11669.8 CBY30346.1 - 3.6e-06 27.5 0.0 6.3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 WW domain-binding protein 1 Pox_EPC_I2-L1 PF12575.8 CBY30346.1 - 0.022 15.0 1.5 0.4 10.9 0.1 2.6 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 BIR PF00653.21 CBY30348.1 - 2.9e-33 114.3 0.3 3.6e-16 59.6 0.1 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CBY30348.1 - 0.00071 19.6 0.0 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 C3HC zinc finger-like PyrI_C PF02748.15 CBY30348.1 - 0.0019 18.0 0.2 2 8.4 0.0 2.4 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 CBY30348.1 - 0.093 13.6 0.1 7 7.8 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.9 CBY30348.1 - 0.35 10.9 4.0 6.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-ribbon_3 PF13248.6 CBY30348.1 - 0.55 9.7 0.2 0.55 9.7 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 CBY30349.1 - 9e-13 47.9 16.6 1.3e-12 47.3 16.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY30349.1 - 0.00036 20.3 15.6 0.00059 19.6 15.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY30349.1 - 0.49 10.4 17.7 0.99 9.4 17.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Fic PF02661.18 CBY30350.1 - 6.3e-27 94.3 0.1 2.2e-26 92.6 0.1 2.0 2 0 0 2 2 1 1 Fic/DOC family TPR_1 PF00515.28 CBY30350.1 - 6.1e-06 25.8 0.0 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY30350.1 - 1.4e-05 24.8 0.0 0.032 14.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY30350.1 - 3.5e-05 24.2 0.1 0.00011 22.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY30350.1 - 3.8e-05 24.1 0.0 0.035 14.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBY30350.1 - 0.0027 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 CBY30350.1 - 0.0078 15.9 0.1 0.063 13.0 0.0 2.3 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 CBY30350.1 - 0.031 14.5 0.0 0.36 11.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CBY30350.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Coatomer epsilon subunit TPR_16 PF13432.6 CBY30350.1 - 0.14 12.8 0.0 0.78 10.4 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY30350.1 - 0.15 12.2 0.0 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Tubulin PF00091.25 CBY30351.1 - 5.9e-64 215.9 0.0 8e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY30351.1 - 1.6e-50 170.4 0.1 2.6e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY30351.1 - 0.0009 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Trypsin PF00089.26 CBY30352.1 - 8.9e-27 94.3 0.0 1.6e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin Mucin PF01456.17 CBY30352.1 - 0.0036 17.3 5.1 0.0036 17.3 5.1 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Shisa PF13908.6 CBY30352.1 - 0.05 13.8 1.5 0.084 13.1 1.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4366 PF14283.6 CBY30352.1 - 0.064 13.3 1.7 0.072 13.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF3439 PF11921.8 CBY30352.1 - 0.39 10.7 6.4 0.75 9.8 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Menin PF05053.13 CBY30352.1 - 0.52 8.6 5.0 0.71 8.2 5.0 1.1 1 0 0 1 1 1 0 Menin Phospholip_A2_1 PF00068.19 CBY30353.1 - 4.6e-14 52.8 7.3 4.6e-14 52.8 7.3 2.1 2 0 0 2 2 2 1 Phospholipase A2 ArsR PF09824.9 CBY30354.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator KIAA1430 PF13879.6 CBY30354.1 - 0.18 12.6 9.6 2.3 9.1 2.4 2.5 2 0 0 2 2 2 0 KIAA1430 homologue Phospholip_A2_1 PF00068.19 CBY30355.1 - 6.7e-13 49.1 6.3 6.7e-13 49.1 6.3 2.2 2 0 0 2 2 2 1 Phospholipase A2 Peptidase_M16_M PF16187.5 CBY30356.1 - 9.9e-58 195.6 0.1 1.8e-57 194.8 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CBY30356.1 - 1.8e-23 83.2 0.0 4.3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY30356.1 - 8.1e-14 52.0 0.1 8.5e-07 29.2 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain gp32 PF08804.10 CBY30356.1 - 0.063 13.3 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 gp32 DNA binding protein like WXG100 PF06013.12 CBY30356.1 - 0.23 11.7 0.2 0.77 10.0 0.0 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG OAM_alpha PF16552.5 CBY30357.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit SNF PF00209.18 CBY30358.1 - 2.8e-131 438.8 27.1 4.8e-131 438.0 27.1 1.3 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family MWFE PF15879.5 CBY30358.1 - 4.5 7.5 6.2 46 4.3 1.8 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit Ephrin_lbd PF01404.19 CBY30359.1 - 0.076 13.1 0.1 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain EF-hand_7 PF13499.6 CBY30360.1 - 2.9e-09 37.2 0.1 3.8e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY30360.1 - 7.1e-09 35.4 0.9 1.3e-08 34.5 0.9 1.5 1 0 0 1 1 1 1 EF-hand domain pair S_100 PF01023.19 CBY30360.1 - 5.2e-08 32.5 0.4 1.1e-07 31.5 0.4 1.5 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_1 PF00036.32 CBY30360.1 - 6.9e-07 28.4 0.9 3e-06 26.4 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBY30360.1 - 7e-06 25.3 0.2 5.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY30360.1 - 4.1e-05 23.2 0.1 0.0015 18.3 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY30360.1 - 0.017 15.4 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY30360.1 - 0.019 14.9 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBY30360.1 - 0.26 11.2 1.7 1.9 8.4 0.3 2.0 1 1 1 2 2 2 0 Caleosin related protein FMN_red PF03358.15 CBY30361.1 - 6.3e-25 87.7 0.0 8e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CBY30361.1 - 3.2e-08 33.5 0.0 2.1e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin-like fold Glyco_transf_4 PF13439.6 CBY30361.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Mucin PF01456.17 CBY30363.1 - 6.9e-05 22.9 28.5 6.9e-05 22.9 28.5 3.7 2 1 1 3 3 3 1 Mucin-like glycoprotein Squash PF00299.18 CBY30363.1 - 0.028 14.5 0.3 0.078 13.0 0.3 1.8 1 0 0 1 1 1 0 Squash family serine protease inhibitor DUF4215 PF13948.6 CBY30363.1 - 4.3 7.9 7.7 6.3 7.3 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) I-set PF07679.16 CBY30364.1 - 5.3e-17 61.7 0.0 1.7e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY30364.1 - 4.3e-10 40.1 0.1 1.6e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CBY30364.1 - 1.5e-06 28.4 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY30364.1 - 3.2e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 CBY30364.1 - 0.025 14.7 0.0 0.098 12.7 0.0 2.0 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY30364.1 - 0.057 13.6 1.5 2.4 8.4 0.0 3.2 2 1 0 2 2 2 0 Immunoglobulin V-set domain Spore_Cse60 PF10957.8 CBY30364.1 - 0.091 12.8 4.1 0.64 10.1 2.7 3.3 1 1 1 2 2 2 0 Sporulation protein Cse60 Astacin PF01400.24 CBY30365.1 - 2e-13 50.4 0.1 1.1e-12 48.0 0.1 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY30365.1 - 1.9e-05 24.7 6.1 1.9e-05 24.7 6.1 3.6 3 0 0 3 3 3 1 Calcium-binding EGF domain Ldl_recept_a PF00057.18 CBY30365.1 - 0.022 14.9 2.9 0.022 14.9 2.9 4.4 3 1 1 4 4 4 0 Low-density lipoprotein receptor domain class A UPF0054 PF02130.17 CBY30365.1 - 0.16 11.8 0.7 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 Kringle PF00051.18 CBY30366.1 - 1.9e-26 92.2 6.2 3.6e-26 91.3 6.2 1.4 1 0 0 1 1 1 1 Kringle domain Aldose_epim PF01263.20 CBY30368.1 - 8.1e-74 248.6 0.4 9.7e-74 248.4 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase MAS20 PF02064.15 CBY30370.1 - 0.86 9.7 7.7 0.13 12.4 3.1 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor RNA_pol_RpbG PF16992.5 CBY30371.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G Alpha-amylase PF00128.24 CBY30372.1 - 1.1e-75 255.3 1.0 1.7e-75 254.7 1.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SLC3A2_N PF16028.5 CBY30372.1 - 0.00099 18.6 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus Zona_pellucida PF00100.23 CBY30373.1 - 1.1e-10 41.7 0.6 1.3e-10 41.6 0.6 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain CPW_WPC PF09717.10 CBY30373.1 - 0.12 13.3 0.0 0.33 11.9 0.0 1.7 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) FtsH_ext PF06480.15 CBY30375.1 - 0.0012 19.2 0.1 0.0017 18.7 0.1 1.2 1 0 0 1 1 1 1 FtsH Extracellular 2OG-FeII_Oxy_3 PF13640.6 CBY30377.1 - 0.00037 21.3 0.0 0.00095 20.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CBY30379.1 - 0.00024 21.9 0.0 0.00074 20.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_1 PF00232.18 CBY30380.1 - 2.6e-135 451.4 5.8 2.9e-135 451.2 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Vac7 PF12751.7 CBY30383.1 - 0.11 11.9 0.2 0.11 11.9 0.2 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 RNA_binding PF01877.17 CBY30384.1 - 0.13 12.6 0.8 0.34 11.2 0.8 1.8 1 0 0 1 1 1 0 RNA binding Abhydrolase_3 PF07859.13 CBY30386.1 - 7.9e-44 150.0 0.0 3.5e-35 121.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CBY30386.1 - 0.00014 20.9 0.0 0.00043 19.3 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 CBY30386.1 - 0.0007 18.6 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family LIDHydrolase PF10230.9 CBY30386.1 - 0.0032 17.0 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 CBY30386.1 - 0.011 15.2 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family UDP-g_GGTase PF06427.11 CBY30387.1 - 0.013 15.6 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase Mad3_BUB1_I_2 PF17014.5 CBY30387.1 - 0.015 15.4 0.3 0.031 14.4 0.3 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein HMG_box PF00505.19 CBY30388.1 - 1.1e-12 48.2 6.5 1.1e-12 48.2 6.5 4.2 2 1 1 3 3 3 1 HMG (high mobility group) box DUF4407 PF14362.6 CBY30388.1 - 8 5.7 19.3 16 4.7 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PLDc_2 PF13091.6 CBY30389.1 - 3.5e-16 59.3 0.1 9.5e-07 28.8 0.1 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBY30389.1 - 0.00041 20.4 1.0 0.23 11.7 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif UPF0167 PF03691.14 CBY30389.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) PTH2 PF01981.16 CBY30390.1 - 1.3e-38 131.9 0.3 2.3e-38 131.1 0.1 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.32 CBY30391.1 - 3.4e-52 173.3 9.8 3.3e-10 40.4 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY30391.1 - 1.3e-22 79.9 0.1 3.4e-05 24.0 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY30391.1 - 3.6e-10 39.7 0.3 0.0042 16.4 0.0 4.1 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CBY30391.1 - 7.9e-08 31.6 3.1 0.1 11.5 0.1 5.7 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY30391.1 - 4.6e-06 25.6 3.8 0.29 9.7 0.0 5.5 3 3 2 6 6 6 1 Nucleoporin Nup120/160 CEP19 PF14933.6 CBY30391.1 - 5.9e-06 26.7 0.5 8.8e-06 26.1 0.5 1.3 1 0 0 1 1 1 1 CEP19-like protein PALB2_WD40 PF16756.5 CBY30391.1 - 0.012 14.5 0.2 2.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DUF5570 PF17731.1 CBY30391.1 - 0.042 13.9 0.3 0.35 11.0 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5570) ELYS-bb PF16687.5 CBY30391.1 - 0.049 12.3 0.0 0.23 10.1 0.0 1.9 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Invasin_D3 PF09134.10 CBY30391.1 - 0.24 11.7 0.7 7.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Invasin, domain 3 Pkinase PF00069.25 CBY30392.1 - 3e-08 33.4 0.0 5.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30392.1 - 5e-05 22.7 0.1 0.00061 19.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase GED PF02212.18 CBY30392.1 - 3.6 7.8 5.0 63 3.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin GTPase effector domain Astacin PF01400.24 CBY30393.1 - 2.7e-28 98.9 2.2 7.1e-28 97.5 2.2 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) FH2 PF02181.23 CBY30393.1 - 8.9e-24 84.3 0.1 2.3e-23 83.0 0.1 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain SHIPPO-rpt PF07004.12 CBY30393.1 - 7.7e-14 51.9 19.6 4.8e-05 24.1 0.9 5.7 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat PDZ PF00595.24 CBY30393.1 - 8.8e-13 48.4 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY30393.1 - 5.8e-09 35.7 0.0 2.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY30393.1 - 0.00026 21.2 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Cnd1 PF12717.7 CBY30393.1 - 0.6 10.1 2.5 9.9 6.2 0.1 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3439 PF11921.8 CBY30393.1 - 0.73 9.8 10.3 1.8 8.5 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 CBY30393.1 - 3.1 7.8 16.6 6.6 6.7 16.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CBY30393.1 - 3.5 5.7 15.1 18 3.4 13.6 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 bZIP_1 PF00170.21 CBY30394.1 - 9.2e-10 38.5 12.8 2.3e-09 37.2 12.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY30394.1 - 7.4e-07 29.2 17.4 4.2e-06 26.8 15.5 2.6 1 1 1 2 2 2 1 Basic region leucine zipper GIT_CC PF16559.5 CBY30394.1 - 0.036 13.9 3.8 0.11 12.4 3.8 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 CBY30394.1 - 1.4 9.5 20.7 0.13 12.8 16.0 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Cnn_1N PF07989.11 CBY30394.1 - 1.9 8.7 10.8 0.18 12.0 3.7 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 LNP1 PF15419.6 CBY30394.1 - 5.6 7.2 13.9 11 6.2 13.9 1.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 CHGN PF05679.16 CBY30395.1 - 1.5e-16 60.4 1.0 2.1e-16 59.9 1.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY30395.1 - 2.9e-10 40.0 0.1 1.1e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 CBY30395.1 - 0.0021 17.9 0.6 0.016 15.0 0.1 2.4 3 0 0 3 3 3 1 Galactosyltransferase CHGN PF05679.16 CBY30396.1 - 2.9e-38 132.0 0.0 3.9e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY30396.1 - 3.6e-07 29.8 0.3 8.1e-07 28.6 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Sulfotransfer_1 PF00685.27 CBY30396.1 - 8.2e-07 28.8 0.1 3.5e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30396.1 - 5.6e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Glycos_transf_2 PF00535.26 CBY30396.1 - 0.022 14.5 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 NTP_transferase PF00483.23 CBY30397.1 - 2.4e-29 102.6 0.0 3.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY30397.1 - 2.2e-08 33.5 4.2 2.1e-06 27.2 0.1 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBY30397.1 - 2.7e-05 24.6 0.0 3.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Ank_2 PF12796.7 CBY30398.1 - 1.3e-19 70.5 0.1 2e-13 50.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY30398.1 - 2.1e-16 60.0 0.5 8e-06 26.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY30398.1 - 3e-13 48.6 0.0 1.5e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY30398.1 - 3.6e-11 43.1 0.1 4.2e-05 23.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY30398.1 - 8.4e-11 41.8 0.6 0.00029 21.1 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Methyltransf_11 PF08241.12 CBY30399.1 - 1.9e-20 73.3 0.1 4.1e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY30399.1 - 3.5e-18 66.0 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY30399.1 - 5.6e-18 65.2 0.1 1.5e-17 63.8 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY30399.1 - 4.4e-17 62.6 0.1 1.2e-16 61.2 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY30399.1 - 3.7e-15 56.5 0.1 6.2e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY30399.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 CBY30399.1 - 2.1e-09 37.3 0.1 3e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 CBY30399.1 - 3.1e-09 36.7 0.2 8.2e-09 35.3 0.1 1.5 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CBY30399.1 - 6.5e-08 31.9 0.0 9.7e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 CBY30399.1 - 4.9e-07 29.3 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 CBY30399.1 - 5.4e-07 29.3 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBY30399.1 - 2e-06 27.4 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CBY30399.1 - 7.4e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CBY30399.1 - 0.00027 20.2 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 CBY30399.1 - 0.0088 15.6 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CBY30399.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CBY30399.1 - 0.062 12.4 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 CBY30399.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ufd2P_core PF10408.9 CBY30400.1 - 2.2e-14 53.0 0.3 3.3e-14 52.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core Ufd2P_core PF10408.9 CBY30402.1 - 5.5e-58 197.1 0.7 8.1e-58 196.5 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CBY30402.1 - 6.4e-21 74.3 0.3 1.1e-20 73.5 0.3 1.4 1 0 0 1 1 1 1 U-box domain NLRC4_HD2 PF17776.1 CBY30402.1 - 0.08 13.5 2.4 0.082 13.5 0.2 2.1 2 1 1 3 3 3 0 NLRC4 helical domain HD2 NAC PF01849.18 CBY30403.1 - 2.2e-24 85.2 0.1 4e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain TPR_12 PF13424.6 CBY30405.1 - 0.092 13.1 0.1 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SRPRB PF09439.10 CBY30406.1 - 2.5e-37 128.0 2.3 3e-37 127.8 2.3 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CBY30406.1 - 1.8e-13 50.3 0.1 2.5e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY30406.1 - 1e-09 38.5 0.1 2e-09 37.5 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY30406.1 - 2e-05 24.2 0.3 3.4e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 CBY30406.1 - 0.00012 22.2 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY30406.1 - 0.0011 18.6 0.5 0.17 11.4 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBY30406.1 - 0.0017 18.5 0.6 0.35 10.9 0.6 2.5 1 1 0 1 1 1 1 Dynamin family Gtr1_RagA PF04670.12 CBY30406.1 - 0.0024 17.3 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRP54 PF00448.22 CBY30406.1 - 0.0044 16.7 0.5 0.027 14.1 0.5 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CBY30406.1 - 0.027 14.6 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CBY30406.1 - 0.032 14.1 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 CBY30406.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase tRNA-synt_1d PF00750.19 CBY30407.1 - 4.1e-25 88.5 0.0 8.6e-25 87.4 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 CBY30407.1 - 0.029 13.7 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 CBY30408.1 - 4.5e-12 45.6 0.4 8.9e-12 44.6 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CBY30408.1 - 2.6e-08 34.0 0.4 5.8e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain SPT16 PF08644.11 CBY30408.1 - 0.48 10.6 2.6 0.37 10.9 0.6 1.7 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Nucleoporin_FG PF13634.6 CBY30411.1 - 1.1 10.1 28.3 4.6 8.1 28.3 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region NPF PF16601.5 CBY30411.1 - 1.2 9.5 17.4 1.4 9.3 10.3 2.1 1 1 1 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif TPR_2 PF07719.17 CBY30412.1 - 5.8e-25 85.4 18.0 1.3e-05 24.9 0.9 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBY30412.1 - 1.5e-23 83.1 6.6 5.9e-06 26.7 0.0 7.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBY30412.1 - 2.6e-23 80.7 2.4 0.013 16.3 0.0 10.0 7 2 3 10 10 10 5 Tetratricopeptide repeat DUF1736 PF08409.11 CBY30412.1 - 3.2e-21 75.1 0.8 3.2e-21 75.1 0.8 2.4 3 0 0 3 3 2 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 CBY30412.1 - 1.2e-20 72.9 9.6 1.2e-07 31.3 0.1 7.1 7 0 0 7 7 7 4 TPR repeat TPR_17 PF13431.6 CBY30412.1 - 3.8e-20 70.7 6.2 0.098 13.1 0.0 9.9 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY30412.1 - 1.8e-19 70.1 0.0 0.063 13.9 0.1 6.3 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY30412.1 - 1e-18 66.3 19.2 4.2e-05 23.2 0.4 8.4 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY30412.1 - 2e-18 65.0 12.6 0.00026 21.0 0.3 8.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY30412.1 - 4.2e-17 62.2 17.0 1.5e-06 28.4 0.9 7.8 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY30412.1 - 7.3e-10 38.2 10.4 0.017 15.1 0.1 7.2 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBY30412.1 - 2e-09 37.0 18.3 0.0068 16.2 0.6 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY30412.1 - 1.9e-08 34.1 7.3 3e-08 33.4 1.4 2.6 3 0 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 CBY30412.1 - 3.7e-08 33.6 2.4 0.063 13.6 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY30412.1 - 1.1e-07 31.9 14.1 0.0079 16.4 0.0 6.5 4 2 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CBY30412.1 - 1.5e-07 31.5 0.1 0.19 11.9 0.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBY30412.1 - 0.00017 21.2 0.9 0.012 15.3 0.1 3.6 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 CBY30412.1 - 0.00022 21.7 16.0 0.37 11.5 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat PPR PF01535.20 CBY30412.1 - 0.0084 16.3 0.1 4.7 7.7 0.0 4.7 4 0 0 4 4 4 1 PPR repeat Mad3_BUB1_I PF08311.12 CBY30412.1 - 0.038 14.0 7.1 0.25 11.4 2.3 4.0 3 2 0 3 3 3 0 Mad3/BUB1 homology region 1 HTH_Bact PF18768.1 CBY30412.1 - 1.4 8.5 6.0 21 4.8 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain TPR_3 PF07720.12 CBY30412.1 - 4.3 7.4 17.4 0.39 10.8 0.4 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat MIT PF04212.18 CBY30412.1 - 4.7 7.4 12.1 2.9 8.0 0.3 4.7 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TAF1_subA PF14929.6 CBY30412.1 - 5.3 6.4 7.8 0.75 9.2 0.3 2.9 3 1 0 3 3 3 0 TAF RNA Polymerase I subunit A Ion_trans PF00520.31 CBY30413.1 - 0.00014 21.2 14.1 0.00019 20.7 14.1 1.2 1 0 0 1 1 1 1 Ion transport protein Lact-deh-memb PF09330.11 CBY30413.1 - 0.019 14.3 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding CitMHS PF03600.16 CBY30413.1 - 0.021 14.1 0.5 0.049 12.8 0.5 1.6 1 1 0 1 1 1 0 Citrate transporter Fib_alpha PF08702.10 CBY30413.1 - 0.97 9.6 7.2 2.3 8.4 7.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Kelch_6 PF13964.6 CBY30414.1 - 9e-12 44.8 0.4 9.9e-07 28.8 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY30414.1 - 4.7e-06 26.5 0.3 0.0054 16.7 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CBY30414.1 - 8.1e-06 26.0 0.0 0.00049 20.3 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY30414.1 - 4.7e-05 23.2 5.6 0.24 11.4 0.0 4.9 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY30414.1 - 0.0001 22.3 0.3 0.13 12.3 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY30414.1 - 0.00052 19.5 4.6 0.015 14.9 0.1 4.0 3 2 0 3 3 3 1 Kelch motif Trypsin PF00089.26 CBY30416.1 - 7.4e-55 186.2 3.3 3.8e-52 177.3 0.1 2.5 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.19 CBY30416.1 - 9.6e-30 102.6 74.2 5.2e-08 33.0 3.6 7.2 6 0 0 6 6 6 6 Thrombospondin type 1 domain CUB PF00431.20 CBY30416.1 - 3.6e-25 88.4 0.0 2.6e-11 43.8 0.0 3.4 3 0 0 3 3 3 2 CUB domain Pentaxin PF00354.17 CBY30416.1 - 4.4e-12 46.1 0.0 9.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Laminin_G_3 PF13385.6 CBY30416.1 - 1.3e-05 25.4 0.1 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Astacin PF01400.24 CBY30418.1 - 4.8e-22 78.5 1.1 2.2e-21 76.3 0.8 2.0 1 1 1 2 2 2 1 Astacin (Peptidase family M12A) Choline_transpo PF04515.12 CBY30419.1 - 5e-97 325.0 35.9 5e-97 325.0 35.9 2.5 3 0 0 3 3 3 1 Plasma-membrane choline transporter TMEM192 PF14802.6 CBY30419.1 - 9.2e-06 24.9 2.8 2.7e-05 23.4 2.8 1.8 1 0 0 1 1 1 1 TMEM192 family PAP2 PF01569.21 CBY30422.1 - 7e-14 51.8 3.0 1.7e-13 50.5 3.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBY30422.1 - 0.00096 18.9 11.3 0.031 14.0 11.3 2.4 1 1 0 1 1 1 1 PAP2 superfamily SGS PF05002.15 CBY30423.1 - 1.1e-34 118.4 6.1 1.1e-34 118.4 6.1 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.16 CBY30423.1 - 4.3e-09 37.3 0.2 9.4e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 CS domain DUF2057 PF09829.9 CBY30423.1 - 0.028 14.6 4.0 0.043 14.0 4.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) AsiA PF09010.10 CBY30423.1 - 0.041 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A Hid1 PF12722.7 CBY30423.1 - 0.15 10.1 4.0 0.17 10.0 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein W_rich_C PF07483.11 CBY30423.1 - 0.21 11.8 3.7 0.29 11.3 0.2 2.6 3 1 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Ribosomal_S27e PF01667.17 CBY30424.1 - 3.6e-23 81.0 5.4 4.5e-23 80.7 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-TAZ PF02135.16 CBY30424.1 - 0.1 13.0 4.9 0.16 12.4 4.9 1.4 1 1 0 1 1 1 0 TAZ zinc finger Ribosomal_L44 PF00935.19 CBY30425.1 - 6.2e-34 116.3 12.4 8.7e-34 115.8 12.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 TerB_N PF13208.6 CBY30426.1 - 0.0064 16.2 0.2 0.013 15.3 0.2 1.5 2 0 0 2 2 2 1 TerB N-terminal domain Med30 PF11315.8 CBY30427.1 - 4.8e-41 140.4 9.1 7.5e-41 139.8 9.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit 30 Hrs_helical PF12210.8 CBY30427.1 - 0.01 16.4 1.5 0.029 14.9 1.4 1.9 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med30 PF11315.8 CBY30428.1 - 1.4e-08 35.1 4.7 1.8e-08 34.7 4.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 Clathrin_lg_ch PF01086.17 CBY30428.1 - 0.06 13.4 0.5 0.086 12.9 0.5 1.2 1 0 0 1 1 1 0 Clathrin light chain RNaseH_like PF04308.12 CBY30428.1 - 0.14 12.1 0.2 0.36 10.7 0.2 1.6 2 0 0 2 2 2 0 Ribonuclease H-like PUB PF09409.10 CBY30429.1 - 2.6e-17 62.5 0.1 7.3e-17 61.1 0.1 1.8 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 CBY30429.1 - 3.6e-05 23.9 0.1 9.7e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 UBX domain PRP21_like_P PF12230.8 CBY30429.1 - 0.0014 18.6 1.3 0.0021 18.0 0.2 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein DUF4857 PF16149.5 CBY30429.1 - 0.03 13.6 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) RF-1 PF00472.20 CBY30429.1 - 0.74 9.8 3.6 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 RF-1 domain Cast PF10174.9 CBY30430.1 - 1.5e-36 126.0 70.4 3.1e-19 68.7 45.5 4.4 1 1 2 3 3 3 3 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.12 CBY30430.1 - 4.2 7.9 12.9 6.4 7.3 0.0 5.6 5 1 2 7 7 7 0 Nucleopolyhedrovirus P10 protein MRG PF05712.13 CBY30431.1 - 3.5e-41 140.7 1.2 3.5e-41 140.7 1.2 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 CBY30431.1 - 3.8e-09 36.3 0.2 8.2e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4537 PF15057.6 CBY30431.1 - 0.093 12.8 0.1 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Flavoprotein PF02441.19 CBY30432.1 - 1.3e-18 67.2 0.0 1.6e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein AAA_13 PF13166.6 CBY30432.1 - 0.22 10.2 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain PutA_N PF18083.1 CBY30433.1 - 0.032 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain DUF4375 PF14300.6 CBY30433.1 - 0.11 12.8 0.2 0.2 11.9 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) AbiJ_NTD4 PF18863.1 CBY30434.1 - 0.078 13.4 0.4 0.14 12.6 0.4 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Endonuclease_NS PF01223.23 CBY30437.1 - 3.2e-08 33.7 0.1 5.3e-08 33.0 0.1 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CBY30438.1 - 0.0096 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ribonuc_2-5A PF06479.12 CBY30440.1 - 2e-11 44.2 3.6 3.7e-11 43.3 0.3 2.3 1 1 1 2 2 2 1 Ribonuclease 2-5A CKS PF01111.19 CBY30441.1 - 7.7e-34 115.8 2.5 8.6e-34 115.6 2.5 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Hepar_II_III_N PF16889.5 CBY30441.1 - 0.048 12.9 1.1 0.048 12.9 1.1 1.0 1 0 0 1 1 1 0 Heparinase II/III N-terminus CBAH PF02275.18 CBY30442.1 - 2.7e-13 50.2 0.0 6.9e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Linear amide C-N hydrolases, choloylglycine hydrolase family NAAA-beta PF15508.6 CBY30442.1 - 7.5e-12 45.4 0.2 2e-11 44.0 0.1 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Carb_kinase PF01256.17 CBY30443.1 - 7.5e-56 189.3 0.0 8.4e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CBY30443.1 - 0.003 17.0 0.0 0.0092 15.4 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 CBY30443.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Rep_fac_C PF08542.11 CBY30443.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain STN1_2 PF09170.10 CBY30445.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Lectin_C PF00059.21 CBY30446.1 - 4.4e-06 27.4 1.8 6e-06 26.9 1.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain Pkinase PF00069.25 CBY30447.1 - 8.5e-58 195.8 0.0 1.8e-57 194.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30447.1 - 4.9e-30 104.7 0.0 2.5e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY30447.1 - 5.4e-06 25.9 0.0 8.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY30447.1 - 1.1e-05 24.4 0.7 6.4e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY30447.1 - 0.00064 18.8 1.1 0.0019 17.2 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY30447.1 - 0.00091 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dynein_AAA_lid PF17852.1 CBY30447.1 - 0.019 15.1 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 Dynein heavy chain AAA lid domain YrbL-PhoP_reg PF10707.9 CBY30447.1 - 0.021 14.3 0.8 0.064 12.8 0.1 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 CBY30447.1 - 0.042 13.2 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY30447.1 - 0.043 13.4 0.1 0.15 11.6 0.1 1.9 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 CBY30447.1 - 0.055 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HEAT_2 PF13646.6 CBY30448.1 - 1.3e-06 28.7 0.0 0.002 18.5 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.7 CBY30448.1 - 0.0017 18.4 1.2 0.13 12.3 0.0 2.4 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY30448.1 - 0.0042 17.5 0.0 0.095 13.2 0.0 2.8 2 1 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 CBY30448.1 - 0.0074 16.5 0.0 3.2 8.2 0.0 3.2 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.23 CBY30448.1 - 0.0095 16.0 0.2 0.39 10.8 0.0 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CBY30448.1 - 0.011 16.4 0.1 1.4 9.6 0.0 2.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region RasGEF PF00617.19 CBY30449.1 - 1.6e-35 122.9 0.4 2.8e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain Asp PF00026.23 CBY30450.1 - 5.4e-119 397.3 0.3 6.3e-119 397.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY30450.1 - 1e-13 51.9 0.4 1.3e-12 48.4 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CBY30450.1 - 2e-05 24.4 0.0 0.00012 21.9 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CBY30450.1 - 0.0055 17.3 0.0 4.2 8.1 0.0 2.9 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CBY30450.1 - 0.014 15.9 0.0 5 7.8 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease FERM_M PF00373.18 CBY30451.1 - 2.6e-12 47.2 1.5 5.4e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CBY30451.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 FERM C-terminal PH-like domain Ntox15 PF15604.6 CBY30451.1 - 0.0017 18.5 2.0 0.044 13.9 0.2 2.6 3 0 0 3 3 3 1 Novel toxin 15 Y_phosphatase PF00102.27 CBY30452.1 - 1.9e-08 34.2 0.0 6.8e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase SH3_13 PF18335.1 CBY30453.1 - 0.015 15.1 0.8 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain Hormone_recep PF00104.30 CBY30454.1 - 4.2e-31 108.2 0.1 6.6e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY30454.1 - 1.7e-28 98.8 18.5 3.7e-28 97.8 18.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) NTF2 PF02136.20 CBY30455.1 - 7.7e-15 55.5 0.1 9.3e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain IPK PF03770.16 CBY30455.1 - 0.012 15.5 1.4 0.015 15.2 0.5 1.5 1 1 1 2 2 2 0 Inositol polyphosphate kinase DUF2524 PF10732.9 CBY30455.1 - 0.076 13.3 1.4 0.18 12.2 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) YccV-like PF08755.11 CBY30455.1 - 0.11 13.0 1.5 0.12 12.9 0.5 1.6 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like Mt_ATP-synt_D PF05873.12 CBY30456.1 - 4.4e-30 104.6 0.3 6.4e-30 104.0 0.3 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) FerA PF08165.11 CBY30456.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain EF-hand_7 PF13499.6 CBY30457.1 - 1.2e-09 38.4 0.1 5.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY30457.1 - 1.5e-06 28.4 0.0 0.043 14.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 CBY30457.1 - 1.8e-06 27.4 0.1 0.0061 16.4 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBY30457.1 - 0.00018 20.8 0.2 0.016 14.7 0.0 2.8 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.10 CBY30457.1 - 0.031 14.3 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2294 PF10057.9 CBY30457.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) NAD_binding_2 PF03446.15 CBY30458.1 - 4.6e-40 137.4 0.0 9e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBY30458.1 - 5.1e-25 88.1 0.4 8.2e-25 87.4 0.4 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PWWP PF00855.17 CBY30458.1 - 1.2e-10 41.6 0.0 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 PWWP domain F420_oxidored PF03807.17 CBY30458.1 - 6e-09 36.4 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CBY30458.1 - 8.5e-06 25.2 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBY30458.1 - 3.2e-05 23.6 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CBY30458.1 - 4.4e-05 23.5 0.0 8.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CBY30458.1 - 0.0011 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 CBY30458.1 - 0.034 14.1 0.6 0.053 13.5 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_N PF05222.15 CBY30458.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain 3HCDH_N PF02737.18 CBY30458.1 - 0.1 12.5 1.2 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBY30458.1 - 0.17 11.4 0.6 7.4 6.1 0.0 2.6 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Striatin PF08232.12 CBY30458.1 - 0.45 11.1 3.7 0.73 10.4 3.7 1.2 1 0 0 1 1 1 0 Striatin family NDUF_B6 PF09782.9 CBY30459.1 - 0.00081 19.6 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit MIF4G PF02854.19 CBY30460.1 - 6e-25 88.1 6.4 9.9e-25 87.4 4.6 2.3 2 1 0 2 2 2 1 MIF4G domain Enkurin PF13864.6 CBY30460.1 - 3.3 8.2 10.0 0.24 11.9 3.1 2.7 2 0 0 2 2 2 0 Calmodulin-binding Glyco_transf_21 PF13506.6 CBY30461.1 - 1.5e-41 141.7 0.0 2.2e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CBY30461.1 - 6.7e-23 81.8 0.0 1e-22 81.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY30461.1 - 3.2e-13 50.1 2.4 4.8e-13 49.5 2.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CBY30461.1 - 3.2e-06 27.0 0.0 9.1e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 TK PF00265.18 CBY30462.1 - 1.1e-63 214.3 0.3 1.4e-63 214.0 0.3 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_16 PF13191.6 CBY30462.1 - 0.018 15.5 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CBY30462.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY30462.1 - 0.088 12.6 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain NUFIP1 PF10453.9 CBY30463.1 - 2.7e-15 55.9 9.0 2.7e-15 55.9 9.0 2.8 3 1 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 CBY30463.1 - 0.00025 21.2 2.4 0.00073 19.8 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Cwf_Cwc_15 PF04889.12 CBY30463.1 - 0.0094 15.7 20.6 0.014 15.1 20.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-met PF12874.7 CBY30463.1 - 0.013 15.9 2.7 0.013 15.9 0.3 2.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 CBY30463.1 - 0.066 12.8 0.2 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Presenilin PF01080.17 CBY30463.1 - 1.1 8.0 7.7 1.4 7.6 7.7 1.3 1 0 0 1 1 1 0 Presenilin zf-C2H2_4 PF13894.6 CBY30463.1 - 9.7 7.3 6.2 2.6 9.1 0.2 2.9 2 1 1 3 3 3 0 C2H2-type zinc finger SH3_9 PF14604.6 CBY30464.1 - 2.9e-43 145.5 0.8 2.1e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CBY30464.1 - 1.4e-37 127.0 4.6 1.7e-12 46.8 0.1 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY30464.1 - 1.2e-30 104.9 0.1 2.7e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain betaPIX_CC PF16523.5 CBY30464.1 - 0.085 12.7 3.0 0.18 11.7 3.0 1.5 1 0 0 1 1 1 0 betaPIX coiled coil RNA_pol_Rpb5_C PF01191.19 CBY30465.1 - 0.00056 19.7 1.4 0.067 13.1 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb5, C-terminal domain Myb_DNA-binding PF00249.31 CBY30465.1 - 0.046 13.9 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ELM2 PF01448.24 CBY30465.1 - 0.075 13.8 0.0 0.075 13.8 0.0 2.7 2 1 0 2 2 2 0 ELM2 domain Myb_DNA-bind_7 PF15963.5 CBY30465.1 - 0.17 11.8 3.7 0.31 11.0 1.8 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Acetyltransf_1 PF00583.25 CBY30466.1 - 6.9e-09 36.0 0.1 1e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY30466.1 - 3.4e-06 27.0 0.1 7.8e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY30466.1 - 1.8e-05 24.6 0.2 4.6e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 CBY30466.1 - 0.00052 20.4 0.2 0.0067 16.8 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain LIM PF00412.22 CBY30467.1 - 3.3e-22 78.5 28.7 1e-11 44.9 12.5 3.7 3 1 0 3 3 3 2 LIM domain UVR PF02151.19 CBY30467.1 - 0.18 11.6 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 UvrB/uvrC motif DZR PF12773.7 CBY30467.1 - 2 8.5 23.9 39 4.4 5.6 3.9 1 1 2 3 3 3 0 Double zinc ribbon DUF5344 PF17279.2 CBY30468.1 - 0.0036 17.8 1.0 0.0036 17.8 1.0 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF5344) AF0941-like PF14591.6 CBY30468.1 - 0.018 15.6 1.1 0.033 14.8 0.9 1.5 1 1 0 1 1 1 0 AF0941-like Prominin PF05478.11 CBY30468.1 - 0.031 12.3 2.4 0.04 11.9 2.4 1.1 1 0 0 1 1 1 0 Prominin DUF3198 PF11433.8 CBY30468.1 - 0.055 13.4 0.3 0.27 11.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) CHB_HEX PF03173.13 CBY30468.1 - 0.059 13.0 1.1 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Putative carbohydrate binding domain TPR_MLP1_2 PF07926.12 CBY30468.1 - 0.08 13.0 7.5 0.064 13.3 3.8 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein mCpol PF18182.1 CBY30468.1 - 0.25 11.7 2.3 0.36 11.2 0.4 2.1 2 1 0 2 2 2 0 minimal CRISPR polymerase domain UPF0242 PF06785.11 CBY30468.1 - 0.28 11.3 5.2 0.39 10.8 5.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 CBY30469.1 - 2.2e-08 34.6 2.7 0.14 13.0 0.0 4.1 3 1 1 4 4 4 3 WD domain, G-beta repeat DUF4394 PF14339.6 CBY30469.1 - 0.11 11.9 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) Homeodomain PF00046.29 CBY30470.1 - 7e-17 61.0 0.5 1.6e-16 59.8 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY30470.1 - 6.3e-06 26.0 2.3 7.1e-05 22.6 0.1 2.9 3 0 0 3 3 3 1 Homeobox KN domain DZR PF12773.7 CBY30470.1 - 0.16 12.0 1.4 0.33 11.0 1.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CBY30470.1 - 0.19 11.9 1.9 0.37 11.0 1.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Trefoil PF00088.18 CBY30473.1 - 0.0097 15.8 8.0 0.014 15.2 8.0 1.3 1 0 0 1 1 1 1 Trefoil (P-type) domain zf-3CxxC_2 PF17180.4 CBY30474.1 - 5e-11 43.2 20.4 1e-09 38.9 5.7 4.1 4 1 1 5 5 5 2 Zinc-binding domain GST_C_3 PF14497.6 CBY30475.1 - 7.1e-07 29.3 0.0 8.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY30475.1 - 5.9e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY30475.1 - 0.00078 19.4 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY30476.1 - 4.2e-15 55.8 0.0 5.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY30476.1 - 6.8e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY30476.1 - 8.1e-12 45.4 0.1 1.1e-11 44.9 0.1 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBY30476.1 - 0.019 15.2 0.0 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin DUF1390 PF07150.11 CBY30476.1 - 0.038 13.7 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) CAP_C PF08603.11 CBY30476.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal GST_C_3 PF14497.6 CBY30477.1 - 7.1e-07 29.3 0.0 8.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY30477.1 - 5.9e-05 23.2 0.0 7.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY30477.1 - 0.00078 19.4 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY30478.1 - 4.2e-15 55.9 0.0 5.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY30478.1 - 7e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY30478.1 - 8.4e-12 45.3 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBY30478.1 - 0.016 15.4 0.0 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin DUF1390 PF07150.11 CBY30478.1 - 0.038 13.7 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) CAP_C PF08603.11 CBY30478.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal VWA PF00092.28 CBY30479.1 - 2.7e-22 79.9 4.0 5.3e-22 78.9 4.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY30479.1 - 3.4e-06 27.7 0.1 1.9e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Phospholip_A2_1 PF00068.19 CBY30482.1 - 3.3e-09 37.2 14.2 3.3e-09 37.2 14.2 2.1 2 1 0 2 2 2 1 Phospholipase A2 MMR_HSR1_C PF08438.10 CBY30482.1 - 0.0082 16.7 0.0 0.032 14.8 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal COesterase PF00135.28 CBY30483.1 - 9.7e-27 94.0 0.0 1.1e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family JmjC PF02373.22 CBY30483.1 - 6.6e-05 23.3 0.1 9.3e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Abhydrolase_3 PF07859.13 CBY30483.1 - 0.00013 21.9 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Reprolysin PF01421.19 CBY30484.1 - 6.6e-13 49.0 0.0 4.8e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Sulfotransfer_3 PF13469.6 CBY30484.1 - 6.3e-12 46.3 0.0 1.4e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Reprolysin_5 PF13688.6 CBY30484.1 - 2e-10 41.1 0.2 4.2e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY30484.1 - 2.1e-08 34.8 0.2 4.6e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CBY30484.1 - 1.2e-07 32.4 30.4 1.2e-07 32.4 30.4 3.7 2 1 0 3 3 1 1 Disintegrin Reprolysin_2 PF13574.6 CBY30484.1 - 1.8e-05 24.8 0.1 4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY30484.1 - 3.4e-05 23.6 0.3 6e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CBY30484.1 - 0.00085 19.0 0.9 0.0045 16.6 0.1 2.1 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Sulfotransfer_1 PF00685.27 CBY30484.1 - 0.0041 16.6 0.1 0.0096 15.4 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Peptidase_M10 PF00413.24 CBY30484.1 - 0.0066 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Matrixin DUF3810 PF12725.7 CBY30484.1 - 0.015 14.6 0.8 0.028 13.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_M54 PF07998.11 CBY30484.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M54 DUF755 PF05501.11 CBY30485.1 - 0.012 15.8 1.2 0.015 15.6 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CKS PF01111.19 CBY30486.1 - 8.7e-35 118.8 0.7 9.5e-35 118.7 0.7 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DcpS_C PF11969.8 CBY30488.1 - 6.4e-26 91.1 0.3 1.2e-25 90.2 0.3 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CBY30488.1 - 7.7e-10 39.5 0.0 1.8e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal zf-C2HE PF16278.5 CBY30488.1 - 0.086 13.3 0.1 0.27 11.7 0.1 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger AtuA PF07287.11 CBY30489.1 - 8e-108 360.3 0.3 1.1e-107 359.8 0.3 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Scramblase PF03803.15 CBY30490.1 - 1.3e-31 109.7 0.5 2.2e-31 108.9 0.5 1.3 1 1 0 1 1 1 1 Scramblase EF-hand_1 PF00036.32 CBY30491.1 - 1.2e-08 33.9 8.1 6.4e-05 22.2 0.1 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY30491.1 - 3.2e-08 32.9 6.0 0.00033 20.3 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY30491.1 - 1.5e-06 28.6 7.3 0.0035 17.8 1.8 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY30491.1 - 0.00096 19.0 6.7 0.24 11.3 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair DUF5601 PF18151.1 CBY30491.1 - 0.022 15.1 7.7 7.2 7.0 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) EF-hand_5 PF13202.6 CBY30491.1 - 0.034 13.7 6.4 0.18 11.4 0.0 3.1 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 CBY30491.1 - 0.058 13.7 2.5 0.35 11.2 0.7 2.9 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3510 PF12022.8 CBY30491.1 - 0.18 12.2 2.1 9.8 6.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Trypsin PF00089.26 CBY30493.1 - 5.6e-49 166.9 0.8 7.4e-49 166.5 0.8 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY30493.1 - 0.00016 22.1 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) CUB PF00431.20 CBY30493.1 - 0.00066 20.0 0.7 0.0016 18.7 0.1 1.9 2 0 0 2 2 2 1 CUB domain PRIMA1 PF16101.5 CBY30493.1 - 0.44 10.6 9.7 2.3 8.3 10.3 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 CBY30493.1 - 1.4 8.3 7.6 2.3 7.6 7.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 CBY30493.1 - 2.8 8.0 6.3 4.2 7.4 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminotran_1_2 PF00155.21 CBY30494.1 - 2.9e-60 204.4 0.0 8.4e-58 196.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CBY30494.1 - 0.00021 20.1 0.0 0.0028 16.4 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-III SepSecS PF05889.13 CBY30494.1 - 0.00051 18.8 0.0 0.00079 18.2 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 CBY30494.1 - 0.00097 17.8 0.1 0.0044 15.6 0.1 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CBY30494.1 - 0.0042 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CBY30494.1 - 0.0043 16.1 0.0 0.015 14.3 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBY30494.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF759 PF05537.11 CBY30494.1 - 0.043 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) LRR_6 PF13516.6 CBY30495.1 - 3.5e-16 57.8 13.8 0.22 11.7 0.0 11.4 12 1 0 12 12 12 4 Leucine Rich repeat LRR_4 PF12799.7 CBY30495.1 - 9.2e-13 48.2 23.0 0.002 18.5 0.5 8.5 4 3 7 11 11 11 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY30495.1 - 0.00013 22.0 15.9 72 4.5 0.1 10.1 10 1 0 10 10 10 0 Leucine Rich Repeat BRCA2 PF00634.18 CBY30495.1 - 0.12 12.0 0.2 0.36 10.5 0.2 1.8 1 0 0 1 1 1 0 BRCA2 repeat Pkinase PF00069.25 CBY30496.1 - 2.2e-31 109.2 0.0 8.5e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30496.1 - 1.5e-29 103.1 0.2 1.5e-28 99.8 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY30496.1 - 8.2e-05 22.3 0.1 0.0019 17.9 0.0 2.6 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY30496.1 - 0.0007 18.5 0.1 0.0013 17.6 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY30496.1 - 0.0078 15.6 0.0 0.063 12.6 0.0 2.3 3 0 0 3 3 3 1 Kinase-like ASFV_J13L PF05568.11 CBY30496.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein MFS_2 PF13347.6 CBY30496.1 - 0.093 11.3 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Fn_bind PF02986.14 CBY30496.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat APH PF01636.23 CBY30496.1 - 0.17 11.8 0.1 1.6 8.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UAF_Rrn10 PF05234.11 CBY30497.1 - 0.043 14.0 0.1 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 Toxin_35 PF10530.9 CBY30498.1 - 6.1 6.9 14.2 9.2 6.3 1.5 2.2 1 1 1 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold EF-hand_1 PF00036.32 CBY30499.1 - 9e-15 53.1 6.3 0.00042 19.7 0.0 4.4 3 1 1 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY30499.1 - 1.1e-13 49.9 1.9 0.00044 19.9 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 CBY30499.1 - 3.7e-12 46.5 1.1 5.5e-05 23.5 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY30499.1 - 3e-10 39.1 4.6 0.00091 18.6 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 CBY30499.1 - 0.00018 21.8 0.0 0.0016 18.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY30499.1 - 0.00057 19.7 7.3 0.34 10.8 0.3 4.4 3 1 1 4 4 4 1 EF-hand domain pair DUF489 PF04356.12 CBY30499.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Excalibur PF05901.11 CBY30499.1 - 4.8 7.9 6.0 13 6.5 0.5 3.1 3 1 0 3 3 3 0 Excalibur calcium-binding domain COesterase PF00135.28 CBY30500.1 - 7.6e-20 71.3 1.2 1.1e-19 70.8 1.2 1.2 1 0 0 1 1 1 1 Carboxylesterase family RRM_1 PF00076.22 CBY30501.1 - 5.9e-16 58.0 0.0 1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAP1_N PF04849.13 CBY30502.1 - 0.0015 17.8 38.7 0.0024 17.1 37.9 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF573 PF04504.14 CBY30502.1 - 0.0017 19.0 3.4 0.0017 19.0 3.4 2.9 2 1 0 2 2 2 1 Protein of unknown function, DUF573 APG6_N PF17675.1 CBY30502.1 - 0.0078 16.8 9.9 0.0078 16.8 9.9 3.1 2 1 1 3 3 2 1 Apg6 coiled-coil region bZIP_1 PF00170.21 CBY30502.1 - 0.012 15.7 0.4 0.012 15.7 0.4 5.3 4 1 1 5 5 5 0 bZIP transcription factor YlqD PF11068.8 CBY30502.1 - 0.015 15.7 9.5 0.015 15.7 9.5 3.1 2 1 1 3 3 3 0 YlqD protein FliT PF05400.13 CBY30502.1 - 0.026 15.3 0.6 0.026 15.3 0.6 3.5 2 2 2 4 4 4 0 Flagellar protein FliT DUF1043 PF06295.12 CBY30502.1 - 0.55 10.2 19.5 0.89 9.6 7.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3452 PF11934.8 CBY30502.1 - 0.56 9.8 6.9 1.3 8.6 0.7 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF3452) MbeD_MobD PF04899.12 CBY30502.1 - 2 8.6 8.8 3.1 8.0 0.2 3.6 3 1 0 3 3 3 0 MbeD/MobD like Osmo_CC PF08946.10 CBY30502.1 - 4.7 7.5 9.4 29 5.0 5.7 3.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DUF3450 PF11932.8 CBY30502.1 - 8.9 5.5 24.2 0.29 10.4 3.6 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3450) Sulfotransfer_2 PF03567.14 CBY30503.1 - 1.1e-18 68.1 0.1 1.5e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY30503.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain DUF2740 PF10872.8 CBY30503.1 - 0.1 12.5 0.6 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) Troponin PF00992.20 CBY30504.1 - 1.8e-05 25.0 27.1 2e-05 24.9 27.1 1.0 1 0 0 1 1 1 1 Troponin DARPP-32 PF05395.12 CBY30504.1 - 0.015 15.5 9.5 0.019 15.2 9.5 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Corazonin PF17308.2 CBY30504.1 - 0.29 11.5 4.5 0.35 11.2 4.3 1.4 1 1 0 1 1 1 0 Pro-corazonin THAP PF05485.12 CBY30504.1 - 0.77 10.7 5.0 1.9 9.5 5.0 1.9 1 1 0 1 1 1 0 THAP domain Synaptobrevin PF00957.21 CBY30504.1 - 1.1 9.1 6.1 0.49 10.2 3.1 1.9 1 1 1 2 2 2 0 Synaptobrevin HSP70 PF00012.20 CBY30504.1 - 4.8 5.3 13.8 5 5.2 13.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Pkinase PF00069.25 CBY30506.1 - 1.2e-22 80.5 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30506.1 - 1.4e-08 34.4 0.0 5.4e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY30506.1 - 2.2e-08 33.3 0.2 2.2e-08 33.3 0.2 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY30506.1 - 0.037 13.9 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sulfatase PF00884.23 CBY30507.1 - 2.6e-51 174.8 0.0 4.2e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY30507.1 - 0.0085 16.8 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 CBY30507.1 - 0.14 12.5 1.2 0.6 10.4 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Gal-3-0_sulfotr PF06990.11 CBY30508.1 - 9.1e-70 235.5 0.8 1.1e-69 235.2 0.8 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_3 PF13469.6 CBY30508.1 - 0.00015 22.2 0.1 0.00068 20.1 0.0 2.0 1 1 1 2 2 2 1 Sulfotransferase family DUF3338 PF11819.8 CBY30508.1 - 0.49 10.4 1.8 32 4.5 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) Sulfotransfer_1 PF00685.27 CBY30510.1 - 6.1e-06 25.9 0.2 6.1e-06 25.9 0.2 2.2 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30510.1 - 0.056 13.8 0.0 0.21 12.0 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase family PDZ PF00595.24 CBY30511.1 - 3.5e-16 59.3 0.3 6.1e-16 58.5 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY30511.1 - 5.1e-12 45.5 0.0 8.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY30511.1 - 1.5e-08 34.8 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 CBY30511.1 - 0.00026 20.9 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF3140 PF11338.8 CBY30511.1 - 0.049 14.1 0.3 0.085 13.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) DUF3618 PF12277.8 CBY30513.1 - 0.22 11.8 2.1 1.7 8.9 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) CUB PF00431.20 CBY30514.1 - 0.00024 21.4 0.0 0.0006 20.1 0.0 1.6 1 1 0 1 1 1 1 CUB domain EGF_CA PF07645.15 CBY30515.1 - 1.6e-132 431.5 635.1 5.8e-10 39.2 4.5 42.3 38 5 5 43 43 43 27 Calcium-binding EGF domain EGF_3 PF12947.7 CBY30515.1 - 3.6e-96 315.0 524.0 2.4e-10 40.4 6.1 39.1 39 2 2 42 42 42 26 EGF domain cEGF PF12662.7 CBY30515.1 - 4.3e-30 103.3 385.6 3.2e-06 27.0 4.8 38.3 36 3 1 37 37 37 22 Complement Clr-like EGF-like TIL PF01826.17 CBY30515.1 - 6.2e-14 52.0 98.5 1e-07 32.1 19.8 34.7 19 9 13 32 32 32 11 Trypsin Inhibitor like cysteine rich domain EGF PF00008.27 CBY30515.1 - 3.6e-11 43.2 479.3 9e-06 25.9 10.8 37.8 37 3 1 38 38 38 19 EGF-like domain EGF_MSP1_1 PF12946.7 CBY30515.1 - 5.5e-11 42.3 371.1 0.0035 17.3 4.4 33.7 31 3 3 34 34 34 17 MSP1 EGF domain 1 hEGF PF12661.7 CBY30515.1 - 0.00035 21.1 15.6 0.00052 20.6 3.9 39.5 43 0 0 43 43 43 18 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY30515.1 - 0.0011 19.1 5.2 0.0011 19.1 5.2 37.4 31 6 6 37 37 37 16 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY30515.1 - 0.0023 18.2 4.2 0.0023 18.2 4.2 36.7 34 5 4 38 38 38 15 Pvs28 EGF domain Zona_pellucida PF00100.23 CBY30516.1 - 6.5e-12 45.8 0.0 7.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain ETRAMP PF09716.10 CBY30516.1 - 0.055 13.5 0.0 0.068 13.2 0.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Marek_A PF02124.15 CBY30516.1 - 0.24 11.2 2.3 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 Marek's disease glycoprotein A ubiquitin PF00240.23 CBY30518.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 CBY30518.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain NADH_dehy_S2_C PF06444.11 CBY30519.1 - 0.0044 17.5 0.2 0.012 16.1 0.2 1.8 1 0 0 1 1 1 1 NADH dehydrogenase subunit 2 C-terminus Lectin_C PF00059.21 CBY30520.1 - 2.4e-44 150.5 26.8 4.8e-18 65.9 1.5 5.2 4 1 1 5 5 5 4 Lectin C-type domain Chordopox_A33R PF05966.12 CBY30520.1 - 3.3e-05 23.3 1.0 0.0056 16.0 0.1 2.3 2 0 0 2 2 2 2 Chordopoxvirus A33R protein UL45 PF05473.12 CBY30520.1 - 0.00021 21.0 0.9 0.75 9.4 0.0 3.2 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Trefoil PF00088.18 CBY30520.1 - 0.0048 16.8 4.0 0.0048 16.8 4.0 2.4 2 0 0 2 2 2 1 Trefoil (P-type) domain SKG6 PF08693.10 CBY30520.1 - 0.28 10.6 2.4 0.48 9.9 2.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NRN1 PF15056.6 CBY30521.1 - 0.031 14.3 4.1 0.042 14.0 4.1 1.3 1 0 0 1 1 1 0 Neuritin protein family DUF1962 PF09227.10 CBY30521.1 - 0.12 12.7 5.0 0.16 12.3 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Astacin PF01400.24 CBY30522.1 - 5.2e-11 42.5 0.0 1.9e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY30523.1 - 7e-07 29.4 0.4 7e-07 29.4 0.4 2.6 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CBY30523.1 - 0.0081 16.1 3.7 0.0081 16.1 3.7 2.6 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY30523.1 - 0.44 10.6 10.8 1.1 9.4 5.2 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Kazal_1 PF00050.21 CBY30524.1 - 1.2e-18 66.9 13.5 1.2e-09 38.0 1.5 3.5 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY30524.1 - 6.6e-18 64.6 24.7 2.5e-10 40.3 2.3 3.9 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain DUF3450 PF11932.8 CBY30525.1 - 0.001 18.4 10.5 0.0014 17.9 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) AAA_13 PF13166.6 CBY30525.1 - 0.0073 15.0 9.0 0.0075 15.0 9.0 1.1 1 0 0 1 1 1 1 AAA domain FTA4 PF13093.6 CBY30525.1 - 0.011 15.6 6.0 0.014 15.3 6.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Retrotrans_gag PF03732.17 CBY30525.1 - 0.067 13.5 3.1 0.14 12.5 3.1 1.6 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4407 PF14362.6 CBY30525.1 - 0.1 11.9 6.4 0.12 11.7 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY30525.1 - 0.21 11.6 18.7 0.46 10.5 18.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phlebovirus_NSM PF07246.11 CBY30525.1 - 0.25 10.7 13.7 0.37 10.1 13.2 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Fez1 PF06818.15 CBY30525.1 - 0.31 11.5 16.5 0.5 10.8 15.9 1.6 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 CBY30525.1 - 0.33 11.6 19.7 0.089 13.4 13.2 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 CBY30525.1 - 0.35 8.7 10.5 0.41 8.5 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5094 PF17015.5 CBY30525.1 - 0.49 10.5 14.7 0.75 9.9 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) APG6_N PF17675.1 CBY30525.1 - 0.5 10.9 20.4 0.17 12.4 16.6 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 CBY30525.1 - 0.84 10.1 14.8 3.2 8.2 14.8 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4337 PF14235.6 CBY30525.1 - 2.5 8.2 12.2 4.3 7.4 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TMPIT PF07851.13 CBY30525.1 - 4.8 6.3 11.2 6.1 6.0 11.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein GPS2_interact PF15784.5 CBY30525.1 - 5.4 7.5 14.8 28 5.2 8.1 3.4 2 1 2 4 4 4 0 G-protein pathway suppressor 2-interacting domain ZapB PF06005.12 CBY30525.1 - 5.9 7.4 20.5 1.4 9.5 9.9 3.0 1 1 1 2 2 2 0 Cell division protein ZapB USP8_interact PF08941.10 CBY30525.1 - 6.1 6.6 11.7 2.1 8.2 4.1 2.2 1 1 1 2 2 2 0 USP8 interacting UAA PF08449.11 CBY30526.1 - 1.4e-30 106.5 9.9 1.8e-30 106.2 9.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY30526.1 - 1.7e-06 27.6 7.5 4e-06 26.4 7.5 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY30526.1 - 0.0017 18.5 8.8 0.0017 18.5 8.8 2.9 2 1 0 2 2 2 1 EamA-like transporter family Ninjurin PF04923.12 CBY30526.1 - 0.0093 15.9 3.0 0.34 10.8 0.3 2.7 2 1 0 2 2 2 2 Ninjurin SET PF00856.28 CBY30528.1 - 8.7e-15 55.5 0.0 1.2e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 SET domain PMP22_Claudin PF00822.20 CBY30531.1 - 1.9e-08 34.4 6.4 2.2e-08 34.1 6.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Peptidase_A24 PF01478.18 CBY30531.1 - 0.0095 16.3 4.8 0.022 15.2 4.8 1.6 1 1 0 1 1 1 1 Type IV leader peptidase family Dynein_light PF01221.18 CBY30531.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 DUF1449 PF07290.11 CBY30531.1 - 0.16 11.6 0.5 0.21 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Prominin PF05478.11 CBY30531.1 - 0.99 7.3 5.1 1.3 6.9 5.1 1.1 1 0 0 1 1 1 0 Prominin ECF_trnsprt PF12822.7 CBY30531.1 - 5.1 7.2 8.9 0.78 9.8 5.4 1.4 2 0 0 2 2 2 0 ECF transporter, substrate-specific component p450 PF00067.22 CBY30532.1 - 1.5e-44 152.5 0.0 1.8e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3281 PF11685.8 CBY30532.1 - 0.18 11.1 0.1 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3281) RhoGAP PF00620.27 CBY30534.1 - 2.2e-22 79.5 0.1 4.8e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Peptidase_C14 PF00656.22 CBY30535.1 - 2e-16 60.7 0.0 3.7e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Caspase domain N-SET PF11764.8 CBY30536.1 - 0.094 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Connexin PF00029.19 CBY30537.1 - 5e-55 186.8 5.0 6.3e-55 186.5 5.0 1.1 1 0 0 1 1 1 1 Connexin 7tm_1 PF00001.21 CBY30537.1 - 0.031 13.6 6.3 0.32 10.3 0.4 2.3 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4133 PF13571.6 CBY30537.1 - 0.048 14.0 1.1 1.7 9.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Mcl1_mid PF12341.8 CBY30538.1 - 1.4e-69 234.7 0.2 8.4e-69 232.2 0.1 2.0 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CBY30538.1 - 2.8e-09 37.2 0.2 4.1e-06 27.0 0.0 3.7 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY30538.1 - 4.4e-06 27.3 0.0 0.0003 21.5 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Kelch_5 PF13854.6 CBY30539.1 - 1.4e-21 76.0 5.4 7.9e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBY30539.1 - 3.4e-18 65.2 1.7 2.4e-08 34.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CBY30539.1 - 2.6e-16 58.9 3.4 2.6e-09 36.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CBY30539.1 - 4.5e-15 55.4 3.3 1.5e-07 31.3 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY30539.1 - 2.1e-13 50.2 0.0 0.00019 21.6 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY30539.1 - 7.4e-11 41.6 8.5 8.3e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CBY30540.1 - 7.6e-05 22.2 0.7 0.00012 21.5 0.2 1.7 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CBY30540.1 - 0.002 18.1 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CBY30540.1 - 0.0093 16.2 0.1 0.53 10.6 0.1 2.6 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY30540.1 - 0.013 15.5 0.2 0.022 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY30540.1 - 0.2 12.0 1.3 2.2 8.7 1.3 2.2 1 1 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY30540.1 - 0.52 10.3 2.5 0.35 10.9 0.5 2.0 2 1 0 2 2 2 0 Galactose oxidase, central domain AAA PF00004.29 CBY30541.1 - 3.6e-19 69.5 0.0 6.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBY30541.1 - 8.2e-19 67.8 1.7 1.3e-18 67.2 0.2 2.1 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY30541.1 - 3.3e-14 53.0 0.0 4.1e-10 39.7 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CBY30541.1 - 1e-09 38.6 0.0 2.2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBY30541.1 - 1.3e-06 28.2 0.1 7.4e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CBY30541.1 - 1.7e-05 24.9 0.1 0.008 16.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_assoc_2 PF16193.5 CBY30541.1 - 2e-05 24.9 0.1 5e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 CBY30541.1 - 2.7e-05 24.2 0.0 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY30541.1 - 3.2e-05 23.9 0.2 0.00027 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY30541.1 - 4.4e-05 23.9 0.0 0.0068 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY30541.1 - 4.6e-05 23.7 0.1 0.0042 17.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY30541.1 - 8.2e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBY30541.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CBY30541.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY30541.1 - 0.00047 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CBY30541.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.13 CBY30541.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 CBY30541.1 - 0.0023 18.3 0.2 0.011 16.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY30541.1 - 0.004 16.9 0.2 0.021 14.6 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBY30541.1 - 0.005 16.6 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY30541.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CBY30541.1 - 0.0098 16.4 0.3 0.047 14.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 CBY30541.1 - 0.011 15.2 0.1 0.058 12.8 0.0 1.9 1 1 1 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 CBY30541.1 - 0.011 15.1 0.1 0.63 9.4 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CBY30541.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CBY30541.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CBY30541.1 - 0.035 13.9 0.1 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBY30541.1 - 0.036 13.8 0.0 5.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain TniB PF05621.11 CBY30541.1 - 0.046 13.1 0.1 2.6 7.4 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 CBY30541.1 - 0.054 13.9 0.3 0.34 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase UQ_con PF00179.26 CBY30542.1 - 1.2e-21 76.8 0.0 2.5e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FKBP_N PF01346.18 CBY30542.1 - 0.16 13.0 3.1 0.43 11.6 3.1 1.7 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FlxA PF14282.6 CBY30542.1 - 2.2 8.3 6.8 3.9 7.5 2.6 2.4 2 0 0 2 2 2 0 FlxA-like protein RVT_1 PF00078.27 CBY30545.1 - 1.1e-10 41.5 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY30545.1 - 0.031 13.8 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Phage_integrase PF00589.22 CBY30546.1 - 1.7e-09 37.7 0.0 4.3e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family RR_TM4-6 PF06459.12 CBY30546.1 - 0.45 10.3 7.2 4.7 7.0 3.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BTB PF00651.31 CBY30547.1 - 9.4e-28 96.7 0.9 2.6e-27 95.3 0.9 1.8 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY30547.1 - 2.5e-27 95.0 0.9 4.4e-27 94.2 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_1 PF01344.25 CBY30547.1 - 2.7e-15 55.6 3.2 7.1e-05 22.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CBY30547.1 - 5.7e-09 35.9 5.9 0.0042 17.3 0.0 4.4 2 1 2 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY30547.1 - 1.6e-05 24.7 0.3 0.038 14.0 0.2 3.2 2 0 0 2 2 2 2 Kelch motif DUF3342 PF11822.8 CBY30547.1 - 0.00067 19.8 0.5 0.0079 16.4 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_4 PF13418.6 CBY30547.1 - 0.2 11.7 4.1 38 4.4 0.1 4.1 3 1 1 4 4 4 0 Galactose oxidase, central domain Zona_pellucida PF00100.23 CBY30548.1 - 7.3e-16 58.7 0.0 1.2e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain TMEM154 PF15102.6 CBY30548.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EGF PF00008.27 CBY30549.1 - 1e-91 300.6 729.9 7.9e-06 26.1 4.9 56.3 54 2 1 55 55 55 46 EGF-like domain hEGF PF12661.7 CBY30549.1 - 0.0014 19.2 1.4 0.0014 19.2 1.4 56.1 57 0 0 57 57 57 28 Human growth factor-like EGF EGF_2 PF07974.13 CBY30549.1 - 0.0039 17.5 5.8 0.0039 17.5 5.8 55.2 53 5 3 56 56 56 36 EGF-like domain DUF1297 PF06973.12 CBY30549.1 - 0.11 12.0 0.6 23 4.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1297) CUB PF00431.20 CBY30550.1 - 1.7e-10 41.2 0.3 2.4e-07 31.1 0.1 2.4 1 1 1 2 2 2 2 CUB domain GATA PF00320.27 CBY30553.1 - 2.2e-28 97.6 15.1 1.5e-15 56.5 4.0 2.3 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY30553.1 - 0.00036 20.0 7.0 0.024 14.1 0.7 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CBY30553.1 - 0.0024 17.9 2.2 1.4 9.1 0.4 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 CBY30553.1 - 0.011 15.9 5.3 0.34 11.1 0.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CBY30553.1 - 0.011 15.6 8.6 0.13 12.2 2.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 CBY30553.1 - 0.1 12.8 6.2 0.12 12.5 0.9 2.9 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 CBY30553.1 - 1.3 9.2 11.5 22 5.2 2.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 CBY30553.1 - 1.4 8.9 4.8 8.7 6.3 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 CBY30553.1 - 3.4 7.9 9.2 73 3.6 9.2 2.4 1 1 0 1 1 1 0 FYVE zinc finger ADK_lid PF05191.14 CBY30553.1 - 4 7.5 10.6 5.8 7.0 1.8 4.2 4 0 0 4 4 4 0 Adenylate kinase, active site lid CUB PF00431.20 CBY30554.1 - 5.7e-08 33.1 0.5 0.0011 19.2 0.1 2.3 2 0 0 2 2 2 2 CUB domain PAP2_C PF14360.6 CBY30556.1 - 8.9e-17 61.4 6.3 1.8e-16 60.4 6.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBY30556.1 - 0.00012 21.8 0.4 0.00016 21.5 0.4 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBY30556.1 - 0.00026 20.7 0.1 0.0003 20.5 0.1 1.2 1 0 0 1 1 1 1 PAP2 superfamily IGFBP PF00219.18 CBY30557.1 - 8.7e-07 29.5 21.8 8.7e-07 29.5 21.8 6.2 4 4 1 5 5 5 1 Insulin-like growth factor binding protein TSP_1 PF00090.19 CBY30557.1 - 0.0033 17.6 10.8 0.0033 17.6 10.8 5.9 8 1 1 9 9 9 1 Thrombospondin type 1 domain TauD PF02668.16 CBY30558.1 - 1.3e-31 110.4 0.0 1.7e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CBY30558.1 - 1.4e-05 25.6 0.1 7e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 CBY30558.1 - 4e-05 22.9 0.1 6.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 CsiD Na_sulph_symp PF00939.19 CBY30559.1 - 2.3e-90 303.9 15.0 3e-90 303.6 15.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY30559.1 - 1.6e-37 129.4 38.4 5.6e-17 61.9 4.1 3.1 2 1 1 3 3 3 3 Citrate transporter ECSCR PF15820.5 CBY30559.1 - 0.025 14.4 0.2 0.087 12.7 0.2 2.0 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SieB PF14163.6 CBY30559.1 - 0.052 13.0 0.2 0.25 10.8 0.2 2.3 1 0 0 1 1 1 0 Super-infection exclusion protein B ETRAMP PF09716.10 CBY30559.1 - 0.07 13.2 0.2 0.07 13.2 0.2 2.8 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Exonuc_VII_L PF02601.15 CBY30560.1 - 4 6.9 11.4 6 6.3 11.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CBY30560.1 - 6 6.1 12.6 8.2 5.7 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EGF_CA PF07645.15 CBY30562.1 - 5.4e-54 180.1 135.1 6.8e-11 42.2 13.1 8.9 8 1 0 8 8 8 7 Calcium-binding EGF domain EGF_3 PF12947.7 CBY30562.1 - 3.9e-45 151.7 156.4 3.2e-09 36.8 17.1 9.0 8 1 1 9 9 9 7 EGF domain EGF PF00008.27 CBY30562.1 - 2.8e-24 85.1 123.0 2.9e-05 24.3 10.9 8.9 8 0 0 8 8 8 7 EGF-like domain hEGF PF12661.7 CBY30562.1 - 3.1e-12 46.6 109.5 0.00015 22.3 5.8 10.5 11 0 0 11 11 11 7 Human growth factor-like EGF cEGF PF12662.7 CBY30562.1 - 1.7e-11 43.8 85.6 0.00025 20.9 5.0 9.5 9 1 0 9 9 9 6 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY30562.1 - 0.00011 22.4 122.6 0.0034 17.6 10.0 8.8 6 3 2 8 8 8 5 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY30562.1 - 0.0011 19.0 99.2 0.0035 17.4 10.5 7.8 7 0 0 7 7 7 5 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY30562.1 - 0.16 12.3 104.9 0.15 12.3 11.4 8.8 7 1 1 8 8 8 0 Pvs28 EGF domain Aldo_ket_red PF00248.21 CBY30563.1 - 1.4e-47 162.3 0.0 1.8e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Utp13 PF08625.11 CBY30563.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Piwi PF02171.17 CBY30564.1 - 0.005 16.1 0.1 0.059 12.6 0.0 1.9 2 0 0 2 2 2 2 Piwi domain zf-H2C2_2 PF13465.6 CBY30566.1 - 1.5e-19 69.4 25.2 2.3e-06 27.7 2.1 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY30566.1 - 4.1e-17 61.6 29.5 2.3e-06 27.7 3.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY30566.1 - 1.2e-15 56.9 25.2 0.00026 21.6 1.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-BED PF02892.15 CBY30566.1 - 1.6e-07 31.2 17.7 0.00075 19.5 3.2 3.6 2 1 2 4 4 4 2 BED zinc finger zf-C2H2_jaz PF12171.8 CBY30566.1 - 6.4e-07 29.5 13.7 0.0026 18.0 0.5 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY30566.1 - 2.9e-06 27.1 20.6 0.012 15.6 1.3 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY30566.1 - 3.5e-06 27.2 11.0 7.4e-06 26.2 3.2 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Cys_rich_CPXG PF14255.6 CBY30566.1 - 0.00064 19.6 3.8 2.5 8.1 0.5 3.7 3 1 0 3 3 3 1 Cysteine-rich CPXCG Zn-ribbon_8 PF09723.10 CBY30566.1 - 0.0019 18.3 9.2 0.21 11.7 1.5 3.6 1 1 3 4 4 4 3 Zinc ribbon domain Prok-RING_1 PF14446.6 CBY30566.1 - 0.002 18.0 8.0 2.8 7.9 0.1 4.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 CBY30566.1 - 0.0025 18.5 6.2 0.58 11.0 0.4 2.3 2 0 0 2 2 2 2 zinc-ribbon family zf-met PF12874.7 CBY30566.1 - 0.0034 17.7 19.0 0.017 15.5 1.5 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Zf_RING PF16744.5 CBY30566.1 - 0.0035 17.4 10.3 0.6 10.3 0.2 3.7 2 1 2 4 4 3 1 KIAA1045 RING finger zf-C2H2_9 PF16293.5 CBY30566.1 - 0.008 16.0 4.2 5 7.0 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_UBZ PF18439.1 CBY30566.1 - 0.012 15.2 12.2 5 6.8 0.3 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 CBY30566.1 - 0.027 15.2 15.5 0.13 13.0 0.5 4.0 2 1 3 5 5 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CBY30566.1 - 0.029 14.7 18.2 3.6 8.0 1.4 4.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 CBY30566.1 - 0.041 14.0 14.5 13 6.0 14.3 3.0 1 1 1 2 2 2 0 FYVE zinc finger HNH_5 PF14279.6 CBY30566.1 - 0.1 12.5 10.1 14 5.6 0.3 4.1 3 1 0 3 3 3 0 HNH endonuclease zf-AN1 PF01428.16 CBY30566.1 - 0.1 12.8 12.6 5.5 7.3 0.2 4.3 4 0 0 4 4 4 0 AN1-like Zinc finger HypA PF01155.19 CBY30566.1 - 0.11 12.5 4.4 4.4 7.3 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 CBY30566.1 - 0.15 11.9 5.6 5.8 6.9 0.2 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 CBY30566.1 - 0.16 11.9 7.3 13 5.9 0.3 3.6 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Zn_ribbon_SprT PF17283.2 CBY30566.1 - 0.17 11.8 9.5 2.9 7.9 2.0 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 CBY30566.1 - 0.24 11.4 13.6 1.4 8.9 2.4 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DZR PF12773.7 CBY30566.1 - 0.36 10.9 7.5 18 5.5 7.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-MYST PF17772.1 CBY30566.1 - 0.41 10.3 6.9 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 MYST family zinc finger domain zf-CHY PF05495.12 CBY30566.1 - 0.44 11.1 16.0 1.4e+02 3.0 0.1 3.0 1 1 1 2 2 2 0 CHY zinc finger GAGA PF09237.11 CBY30566.1 - 0.67 9.8 9.4 0.6 10.0 0.1 4.0 2 1 3 5 5 4 0 GAGA factor Zn-C2H2_12 PF18112.1 CBY30566.1 - 0.7 10.4 11.1 3.2 8.3 0.5 4.7 5 0 0 5 5 4 0 Autophagy receptor zinc finger-C2H2 domain FYDLN_acid PF09538.10 CBY30566.1 - 0.92 10.2 5.4 28 5.5 0.5 4.0 2 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Endonuclease_7 PF02945.15 CBY30566.1 - 1.3 9.0 9.3 5 7.1 2.4 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII zf_ZIC PF18366.1 CBY30566.1 - 2.1 8.5 9.4 1.4 9.1 0.3 3.2 1 1 2 3 3 3 0 Zic proteins zinc finger domain zinc-ribbons_6 PF07191.12 CBY30566.1 - 2.3 8.3 9.7 16 5.5 0.5 3.1 1 1 2 3 3 3 0 zinc-ribbons DUF3268 PF11672.8 CBY30566.1 - 3.6 7.9 7.0 8.7 6.7 0.8 3.0 2 1 1 3 3 3 0 zinc-finger-containing domain LIM PF00412.22 CBY30566.1 - 4.7 7.5 9.3 7.5 6.9 0.6 3.3 1 1 2 3 3 3 0 LIM domain zf-CHCC PF10276.9 CBY30566.1 - 6.5 6.9 11.6 3.7 7.7 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger domain Zn_Tnp_IS1595 PF12760.7 CBY30566.1 - 8.3 6.5 15.9 12 5.9 0.5 3.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Phage_fiber_C PF06820.12 CBY30567.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Glyco_transf_7N PF13733.6 CBY30568.1 - 8.5e-39 132.3 0.0 1.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY30568.1 - 3.9e-24 84.1 0.5 7.5e-24 83.2 0.5 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Kelch_6 PF13964.6 CBY30569.1 - 1.4e-07 31.5 3.4 0.022 15.0 0.3 4.2 3 1 1 4 4 4 3 Kelch motif TSP_1 PF00090.19 CBY30569.1 - 1.1e-05 25.6 3.8 1.1e-05 25.6 3.8 3.2 3 1 0 3 3 3 1 Thrombospondin type 1 domain Kelch_1 PF01344.25 CBY30569.1 - 0.0012 18.4 0.0 0.4 10.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY30569.1 - 0.0025 17.8 0.0 0.66 10.0 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY30569.1 - 0.004 17.1 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 Kelch motif OmpH PF03938.14 CBY30569.1 - 0.01 16.2 2.2 0.59 10.5 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Kelch_3 PF13415.6 CBY30569.1 - 0.022 15.1 0.0 48 4.4 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain UNC45-central PF11701.8 CBY30569.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central CAP18_C PF12153.8 CBY30569.1 - 0.36 10.7 2.1 0.97 9.4 2.1 1.7 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) COesterase PF00135.28 CBY30570.1 - 6.6e-136 454.2 0.0 8.1e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY30570.1 - 5e-08 33.1 0.0 2.1e-07 31.0 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold AChE_tetra PF08674.10 CBY30570.1 - 9.3e-05 22.0 3.5 0.00036 20.2 3.5 2.0 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Peptidase_S9 PF00326.21 CBY30570.1 - 0.0021 17.6 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_11 PF08241.12 CBY30571.1 - 3e-11 43.8 0.1 8e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY30571.1 - 1.2e-09 38.8 0.1 4.9e-09 36.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY30571.1 - 2.2e-08 34.1 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY30571.1 - 2.7e-07 31.2 0.1 1e-06 29.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY30571.1 - 2.3e-06 27.1 0.1 0.00021 20.7 0.1 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CBY30571.1 - 1.7e-05 24.7 0.0 3.3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY30571.1 - 0.12 12.3 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain CdiI PF07262.11 CBY30572.1 - 0.031 14.0 0.9 0.04 13.7 0.9 1.1 1 0 0 1 1 1 0 CDI immunity protein Bclt PF15318.6 CBY30572.1 - 0.04 13.8 0.6 0.057 13.3 0.6 1.1 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis ADH_zinc_N PF00107.26 CBY30574.1 - 1.9e-21 76.4 0.0 2.4e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBY30574.1 - 3.6e-11 44.2 0.0 4.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY30574.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Cauli_VI PF01693.16 CBY30574.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin ADH_N PF08240.12 CBY30575.1 - 1.1e-23 83.1 3.8 1.4e-23 82.8 3.8 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.28 CBY30576.1 - 1.6e-67 228.5 0.0 5.8e-67 226.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY30576.1 - 3.1e-05 23.9 0.0 0.00012 22.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CBY30576.1 - 0.014 14.3 0.0 0.04 12.8 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase DUF2663 PF10864.8 CBY30577.1 - 1.4 9.4 8.3 0.082 13.3 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF1279 PF06916.13 CBY30577.1 - 8.4 7.0 8.4 7.4 7.2 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1279) Cgr1 PF03879.14 CBY30578.1 - 0.015 15.6 1.1 0.018 15.4 1.1 1.1 1 0 0 1 1 1 0 Cgr1 family Cep57_MT_bd PF06657.13 CBY30578.1 - 0.2 12.1 2.0 0.3 11.5 2.0 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short_C2 PF13561.6 CBY30579.1 - 1.2e-47 162.4 0.2 1.5e-47 162.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY30579.1 - 1.4e-42 145.4 1.8 1.8e-42 145.0 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY30579.1 - 5.1e-11 42.8 0.2 8e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY30579.1 - 0.00036 21.1 0.1 0.00085 19.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 CBY30579.1 - 0.039 14.5 0.8 0.071 13.7 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CBY30579.1 - 0.061 13.2 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CBY30579.1 - 0.07 12.3 0.6 0.39 9.8 0.3 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein TPR_19 PF14559.6 CBY30580.1 - 8.7e-36 122.3 6.9 0.0006 20.3 0.0 11.3 5 3 5 12 12 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 CBY30580.1 - 6.8e-35 116.4 36.2 2.9e-05 23.8 1.7 16.3 16 1 0 16 16 16 9 Tetratricopeptide repeat TPR_1 PF00515.28 CBY30580.1 - 3.6e-33 112.0 33.1 8.4e-05 22.2 0.0 13.8 14 1 0 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBY30580.1 - 2.8e-26 89.5 16.8 4.9e-05 23.2 0.5 13.7 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBY30580.1 - 1.3e-25 87.9 8.6 0.85 10.6 0.0 15.3 10 4 7 17 17 17 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY30580.1 - 2.7e-25 86.9 21.6 0.16 12.4 0.0 15.6 14 1 1 15 15 15 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBY30580.1 - 7.9e-24 83.1 14.3 7.8e-05 22.3 0.0 11.6 10 3 2 12 12 12 5 TPR repeat TPR_12 PF13424.6 CBY30580.1 - 5e-22 78.0 24.3 0.0039 17.4 0.9 11.0 5 2 7 13 13 13 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBY30580.1 - 9.2e-20 69.2 10.7 0.0034 17.3 0.4 11.7 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY30580.1 - 1.2e-18 67.4 10.1 0.084 13.5 0.0 10.3 7 2 4 12 12 11 7 Tetratricopeptide repeat TPR_6 PF13174.6 CBY30580.1 - 2e-16 59.4 24.0 0.054 14.1 0.0 13.7 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBY30580.1 - 8.3e-12 45.1 2.0 0.15 12.2 0.0 7.4 5 2 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY30580.1 - 1.3e-10 41.3 16.2 0.054 13.7 1.9 7.5 4 3 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 CBY30580.1 - 0.0021 18.7 9.7 0.045 14.4 1.8 3.9 4 0 0 4 4 2 2 Sel1 repeat Rapsyn_N PF10579.9 CBY30580.1 - 0.0022 18.0 2.3 3.6 7.8 0.0 5.7 5 2 1 6 6 5 1 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.6 CBY30580.1 - 0.0024 17.7 33.7 0.67 9.9 0.9 11.8 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_4 PF07721.14 CBY30580.1 - 0.0045 17.5 6.5 8.8 7.3 0.0 5.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4810 PF16068.5 CBY30580.1 - 0.071 13.7 0.0 0.071 13.7 0.0 4.8 6 0 0 6 6 3 0 Domain of unknown function (DUF4810) TPR_21 PF09976.9 CBY30580.1 - 0.089 12.5 0.1 0.089 12.5 0.1 4.9 4 1 0 5 5 5 0 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 CBY30580.1 - 0.27 11.3 8.2 37 4.4 0.9 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FlbT PF07378.11 CBY30580.1 - 1.7 8.7 6.6 0.25 11.4 0.1 3.0 3 0 0 3 3 3 0 Flagellar protein FlbT Fis1_TPR_C PF14853.6 CBY30580.1 - 9.8 6.3 8.2 4.4 7.5 1.1 4.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Trypsin PF00089.26 CBY30581.1 - 1.8e-06 28.0 0.1 5.8e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY30581.1 - 0.0022 18.9 0.0 0.0039 18.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY30581.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Zona_pellucida PF00100.23 CBY30582.1 - 5.8e-22 78.7 1.1 8.8e-22 78.1 1.1 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain Mvb12 PF09452.10 CBY30583.1 - 0.076 13.5 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 Galactosyl_T PF01762.21 CBY30584.1 - 8.1e-15 55.2 2.9 1.9e-14 54.0 2.9 1.6 1 0 0 1 1 1 1 Galactosyltransferase TrmO PF01980.16 CBY30584.1 - 0.091 13.0 0.1 0.76 10.0 0.0 2.3 2 1 1 3 3 3 0 tRNA-methyltransferase O CBM_14 PF01607.24 CBY30585.1 - 2.5e-15 56.4 4.0 3.4e-15 55.9 4.0 1.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain DUF3439 PF11921.8 CBY30585.1 - 0.012 15.6 8.3 0.019 14.9 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CBY30585.1 - 0.13 10.5 6.6 0.16 10.2 6.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.11 CBY30585.1 - 5.1 7.0 6.2 6.4 6.7 6.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Phospholip_A2_1 PF00068.19 CBY30586.1 - 4.4e-19 69.0 6.3 4.4e-19 69.0 6.3 2.1 2 0 0 2 2 2 1 Phospholipase A2 Laminin_N PF00055.17 CBY30588.1 - 1.1e-55 188.8 5.2 1.1e-55 188.8 5.2 2.6 2 1 1 3 3 3 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY30588.1 - 8.3e-10 38.7 44.5 1.5e-06 28.3 13.2 3.5 3 0 0 3 3 3 2 Laminin EGF domain NTR PF01759.21 CBY30588.1 - 1.9e-08 34.1 9.5 3.6e-06 26.7 0.9 2.6 1 1 1 2 2 2 2 UNC-6/NTR/C345C module Amidinotransf PF02274.17 CBY30590.1 - 0.007 15.5 0.0 0.35 9.9 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase Sulfotransfer_1 PF00685.27 CBY30591.1 - 7.8e-20 71.5 0.4 1.1e-19 71.0 0.4 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30591.1 - 4e-12 47.0 0.0 8.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family Gal_Lectin PF02140.18 CBY30592.1 - 6.2e-28 97.1 21.0 1.7e-15 57.2 2.5 3.4 3 0 0 3 3 3 2 Galactose binding lectin domain Astacin PF01400.24 CBY30593.1 - 3.9e-53 179.9 0.0 6.3e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY30593.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Matrixin LMBR1 PF04791.16 CBY30595.1 - 3.8 6.3 7.7 5 5.9 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP_sp32 PF07222.12 CBY30595.1 - 5.8 6.3 15.7 14 5.0 15.7 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Paramyxo_ncap PF00973.19 CBY30595.1 - 6.1 5.6 8.0 9 5.1 8.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SLC12 PF03522.15 CBY30595.1 - 7 5.6 21.1 3.2 6.7 17.7 2.0 2 0 0 2 2 2 0 Solute carrier family 12 SHE3 PF17078.5 CBY30597.1 - 4.4e-05 23.3 4.6 5.5e-05 23.0 4.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 HAP1_N PF04849.13 CBY30597.1 - 0.00019 20.7 0.8 0.00023 20.5 0.8 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region EzrA PF06160.12 CBY30597.1 - 0.0034 15.6 3.7 0.0044 15.2 3.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 CBY30597.1 - 0.0056 16.9 0.1 0.0089 16.2 0.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CBY30597.1 - 0.014 15.5 1.8 0.014 15.5 1.8 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 CBY30597.1 - 0.021 14.2 2.1 0.029 13.7 2.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 CBY30597.1 - 0.089 12.9 3.6 0.16 12.0 3.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 CBY30597.1 - 0.11 12.7 5.5 0.2 11.9 0.3 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 CBY30597.1 - 0.48 10.0 8.4 0.085 12.5 2.3 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF2325 PF10087.9 CBY30597.1 - 7.2 6.8 7.8 5 7.3 0.0 3.4 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2325) ELFV_dehydrog_N PF02812.18 CBY30598.1 - 1.7e-20 73.2 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Tudor-knot PF11717.8 CBY30599.1 - 3.3e-12 46.1 1.5 1.2e-11 44.3 1.0 2.3 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain BRK PF07533.16 CBY30599.1 - 5.1e-05 22.8 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 BRK domain Chromo PF00385.24 CBY30599.1 - 0.0061 16.4 0.4 0.023 14.6 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PLATZ PF04640.14 CBY30599.1 - 0.014 16.0 0.7 0.014 16.0 0.7 2.6 2 0 0 2 2 2 0 PLATZ transcription factor AT_hook PF02178.19 CBY30599.1 - 0.32 11.0 4.2 1.5 8.9 4.2 2.3 1 0 0 1 1 1 0 AT hook motif DUF2116 PF09889.9 CBY30599.1 - 1.3 9.1 4.1 4 7.5 4.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3006 PF11213.8 CBY30600.1 - 0.049 13.9 0.4 29 5.0 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF3006) Y_phosphatase PF00102.27 CBY30602.1 - 2.5e-60 204.0 1.2 5.9e-32 111.1 0.1 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY30602.1 - 0.0014 18.6 0.1 0.011 15.7 0.0 2.1 1 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CBY30602.1 - 0.003 17.4 0.3 0.011 15.5 0.3 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY30602.1 - 0.017 15.2 0.1 0.075 13.1 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CBY30602.1 - 0.031 13.8 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.20 CBY30602.1 - 0.1 13.2 0.0 8 7.0 0.0 2.9 2 0 0 2 2 2 0 Rhodanese-like domain PLAT PF01477.23 CBY30603.1 - 0.0037 17.8 0.0 0.89 10.1 0.0 2.5 2 0 0 2 2 2 2 PLAT/LH2 domain DUF1217 PF06748.12 CBY30603.1 - 0.043 13.8 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) ADH_zinc_N PF00107.26 CBY30604.1 - 0.002 18.1 0.0 4.1 7.4 0.0 2.8 2 0 0 2 2 2 2 Zinc-binding dehydrogenase DUF4959 PF16323.5 CBY30604.1 - 0.053 13.9 0.2 13 6.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) NESP55 PF06390.12 CBY30604.1 - 0.064 12.9 1.5 0.25 10.9 0.1 2.2 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Cas9_PI2 PF18070.1 CBY30604.1 - 0.78 10.5 3.6 30 5.5 0.4 2.8 2 0 0 2 2 2 0 CRISPR-Cas9 PI domain AAT PF03417.16 CBY30605.1 - 0.0011 18.7 0.1 0.0019 17.9 0.0 1.4 2 0 0 2 2 2 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PAX PF00292.18 CBY30607.1 - 5e-35 120.1 0.3 9.1e-35 119.3 0.3 1.4 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY30607.1 - 1.8e-20 72.5 1.2 1.8e-20 72.5 1.2 2.8 4 0 0 4 4 4 1 Homeodomain Homeobox_KN PF05920.11 CBY30607.1 - 6.2e-05 22.8 0.1 0.00016 21.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HTH_32 PF13565.6 CBY30607.1 - 0.0013 19.3 0.1 0.022 15.4 0.0 2.7 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 CBY30607.1 - 0.012 15.6 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 CBY30607.1 - 0.017 14.9 0.1 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain PI-PLC-X PF00388.19 CBY30608.1 - 2.2e-59 199.2 0.0 3.2e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY30608.1 - 4.1e-38 130.3 0.1 6.3e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBY30608.1 - 2.6e-12 46.9 0.0 4.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 CBY30608.1 - 2.9e-08 33.0 0.8 0.00027 20.6 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY30608.1 - 6.8e-07 29.7 0.1 1.2e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY30608.1 - 3.6e-06 26.1 0.4 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_like PF09279.11 CBY30608.1 - 8.7e-06 26.1 0.4 1.7e-05 25.2 0.4 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.6 CBY30608.1 - 0.00014 21.6 0.3 0.00031 20.5 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CBY30608.1 - 0.0011 18.4 0.5 0.024 14.1 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY30608.1 - 0.039 13.8 0.6 0.86 9.5 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain pair Caleosin PF05042.13 CBY30608.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Caleosin related protein Ank_2 PF12796.7 CBY30609.1 - 6.4e-73 241.4 40.7 1.2e-12 48.2 0.4 7.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY30609.1 - 8.7e-58 192.0 23.3 2.7e-09 37.4 0.1 12.0 4 2 10 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY30609.1 - 4.1e-54 179.9 21.2 3.2e-08 33.7 0.4 11.0 5 4 6 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.30 CBY30609.1 - 1.4e-53 177.1 31.3 0.00012 22.3 0.3 14.2 15 0 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.6 CBY30609.1 - 6e-52 167.5 13.6 5.1e-05 23.4 0.3 14.4 14 0 0 14 14 14 12 Ankyrin repeat IQ PF00612.27 CBY30609.1 - 0.1 12.4 0.4 0.25 11.2 0.4 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fringe PF02434.16 CBY30610.1 - 9.1e-54 182.5 0.0 1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CBY30610.1 - 5.2e-05 23.2 0.0 0.0031 17.3 0.0 2.2 1 1 0 1 1 1 1 Galactosyltransferase Glyco_transf_21 PF13506.6 CBY30610.1 - 0.0006 19.3 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF604 PF04646.12 CBY30610.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Glycos_transf_2 PF00535.26 CBY30610.1 - 0.07 12.9 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 PBP PF01161.20 CBY30611.1 - 6.9e-15 55.5 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LRR_4 PF12799.7 CBY30612.1 - 4e-15 55.7 9.0 4.5e-05 23.7 2.5 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY30612.1 - 4.8e-15 55.1 6.5 1.4e-05 24.8 0.2 3.3 2 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBY30612.1 - 8.9e-05 22.1 4.3 0.0082 15.7 1.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY30612.1 - 0.00035 20.7 12.7 3.2 8.6 0.3 6.2 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY30612.1 - 0.0037 17.2 3.5 9.8 6.5 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat Troponin PF00992.20 CBY30613.1 - 1.5e-25 90.0 16.1 1.7e-25 89.9 16.1 1.0 1 0 0 1 1 1 1 Troponin DUF3584 PF12128.8 CBY30613.1 - 0.0019 15.8 6.5 0.0021 15.7 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BssS PF13991.6 CBY30613.1 - 0.044 13.8 0.1 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 BssS protein family SWI-SNF_Ssr4 PF08549.10 CBY30613.1 - 0.058 12.0 4.2 0.065 11.9 4.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SLATT_fungal PF18142.1 CBY30613.1 - 0.065 13.2 1.1 0.1 12.6 1.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain XhlA PF10779.9 CBY30613.1 - 0.22 11.8 4.5 2.6 8.3 1.6 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 CBY30613.1 - 1.1 9.4 12.8 1.6 9.0 12.8 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3810 PF12725.7 CBY30613.1 - 2.6 7.3 5.3 3.7 6.8 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) DUF1003 PF06210.11 CBY30613.1 - 2.9 8.0 4.6 2.1 8.5 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) TMPIT PF07851.13 CBY30613.1 - 6 6.0 5.5 5.9 6.0 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein BTB PF00651.31 CBY30614.1 - 6.5e-16 58.5 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 CBY30614.1 - 9.8e-13 47.9 13.0 8.3e-08 32.3 0.3 4.0 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY30614.1 - 1.1e-10 41.4 18.3 9.5e-05 22.7 1.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY30614.1 - 8.9e-08 32.4 16.1 0.002 18.8 0.7 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY30614.1 - 0.00014 21.7 15.9 0.00052 19.9 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CBY30614.1 - 0.073 13.5 11.5 0.66 10.5 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY30614.1 - 0.3 11.2 3.6 8.5 6.6 1.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY30614.1 - 0.4 11.0 10.6 0.86 10.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY30614.1 - 0.57 10.6 8.5 8.4 6.8 0.2 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3 PF13878.6 CBY30614.1 - 0.66 9.8 6.3 0.61 10.0 1.9 3.0 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2HE PF16278.5 CBY30614.1 - 1.2 9.6 6.3 6.8 7.2 0.1 3.6 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 CBY30614.1 - 2.3 8.8 4.9 31 5.2 0.2 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 CBY30614.1 - 3.2 8.1 12.5 3.4 8.0 0.2 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Tubulin PF00091.25 CBY30615.1 - 1.8e-51 175.1 0.0 3.1e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY30615.1 - 0.0016 18.6 0.0 0.04 14.1 0.0 2.3 1 1 0 1 1 1 1 Tubulin C-terminal domain Astacin PF01400.24 CBY30616.1 - 8.3e-22 77.7 0.0 3e-19 69.4 0.0 3.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_3 PF12947.7 CBY30616.1 - 3.7e-10 39.8 32.0 2.7e-06 27.5 9.5 5.2 4 1 0 4 4 4 2 EGF domain EGF_CA PF07645.15 CBY30616.1 - 1.5e-05 25.1 14.7 1.5e-05 25.1 14.7 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain EGF PF00008.27 CBY30616.1 - 0.00019 21.7 29.3 0.011 16.0 7.3 4.0 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY30616.1 - 0.0063 16.4 17.9 0.031 14.2 2.2 3.8 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY30616.1 - 0.0071 16.4 26.8 0.031 14.3 5.2 3.6 3 0 0 3 3 3 2 MSP1 EGF domain 1 Ldl_recept_a PF00057.18 CBY30616.1 - 0.02 15.1 0.1 0.02 15.1 0.1 5.0 5 0 0 5 5 5 0 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY30616.1 - 0.025 15.2 4.9 0.025 15.2 4.9 5.5 6 0 0 6 6 6 0 Human growth factor-like EGF DUF4064 PF13273.6 CBY30617.1 - 0.047 14.0 3.8 5.4 7.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SecG PF03840.14 CBY30617.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.9 2 1 1 3 3 3 0 Preprotein translocase SecG subunit DUF4231 PF14015.6 CBY30617.1 - 0.24 11.9 7.9 1.3 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2157 PF09925.9 CBY30617.1 - 0.37 10.6 6.6 0.78 9.5 4.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) 7TMR-DISM_7TM PF07695.11 CBY30617.1 - 6.9 6.5 12.4 25 4.7 4.6 3.0 3 0 0 3 3 3 0 7TM diverse intracellular signalling SUR7 PF06687.12 CBY30617.1 - 9.5 5.8 14.1 0.34 10.5 0.1 2.6 2 1 1 3 3 3 0 SUR7/PalI family Jagunal PF07086.12 CBY30618.1 - 0.85 9.7 6.7 1.1 9.3 6.7 1.1 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF2070 PF09843.9 CBY30618.1 - 9.6 4.4 13.9 12 4.0 13.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CDO_I PF05995.12 CBY30619.1 - 6.8e-42 142.6 0.0 8.5e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY30619.1 - 0.0026 17.2 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO zf-C2H2 PF00096.26 CBY30620.1 - 4.2e-07 30.1 9.7 0.0032 17.8 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY30620.1 - 2e-05 24.8 5.5 0.019 15.4 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY30620.1 - 0.014 16.2 0.2 0.014 16.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY30620.1 - 0.097 13.0 3.2 3.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY30620.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain FTH PF01827.27 CBY30622.1 - 0.014 15.2 0.1 0.033 14.0 0.1 1.6 1 1 0 1 1 1 0 FTH domain GCP_C_terminal PF04130.13 CBY30624.1 - 3.6e-52 177.7 8.0 4.3e-52 177.5 8.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF2935 PF11155.8 CBY30624.1 - 0.043 14.1 0.5 0.043 14.1 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Vps54 PF07928.12 CBY30624.1 - 0.079 13.4 0.9 0.12 12.8 0.9 1.3 1 0 0 1 1 1 0 Vps54-like protein DUF999 PF06198.11 CBY30624.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) GCP_N_terminal PF17681.1 CBY30625.1 - 7.6e-16 58.6 0.0 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CBY30625.1 - 8.6e-16 58.3 0.6 1.3e-15 57.6 0.2 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBY30626.1 - 1.7e-07 31.1 0.1 3.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Rotamase PF00639.21 CBY30627.1 - 4.2e-23 82.1 0.0 5.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBY30627.1 - 3.4e-21 76.0 0.0 4.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CBY30627.1 - 7.7e-13 48.3 0.5 1.3e-12 47.5 0.5 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CBY30627.1 - 0.00018 22.3 0.0 0.00023 22.0 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain SH3_9 PF14604.6 CBY30628.1 - 9.8e-15 54.2 0.1 1.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY30628.1 - 2.4e-13 49.5 0.1 4.6e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 CBY30628.1 - 6.7e-13 48.7 0.3 6.7e-13 48.7 0.3 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CBY30628.1 - 2.3e-07 30.4 0.0 5.6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF3560 PF12083.8 CBY30628.1 - 6.6 6.9 16.1 0.35 11.0 7.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) zf-RING_2 PF13639.6 CBY30629.1 - 3.5e-14 52.9 6.5 6.6e-14 52.0 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY30629.1 - 3.9e-12 45.8 6.1 7.7e-12 44.9 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY30629.1 - 8e-11 41.5 3.9 1.8e-10 40.4 3.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBY30629.1 - 2.9e-08 33.4 4.8 5.5e-08 32.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY30629.1 - 7.2e-08 32.6 7.4 7.2e-08 32.6 7.4 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY30629.1 - 1.2e-07 31.6 3.2 2.4e-07 30.6 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY30629.1 - 9.6e-07 28.6 3.2 1.5e-06 27.9 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY30629.1 - 2.3e-06 27.5 3.4 4e-06 26.7 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBY30629.1 - 0.0022 17.6 3.6 0.004 16.8 3.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY30629.1 - 0.0023 17.7 4.1 0.0051 16.6 4.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CBY30629.1 - 0.0029 17.6 3.4 0.0029 17.6 3.4 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CBY30629.1 - 0.014 15.7 3.3 0.036 14.4 3.3 1.8 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CBY30629.1 - 0.017 15.3 4.3 0.055 13.6 4.3 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 CBY30629.1 - 0.021 15.1 2.0 0.032 14.5 1.0 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain LAP1C PF05609.12 CBY30629.1 - 0.036 13.2 14.5 0.057 12.5 14.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf-C3H2C3 PF17122.5 CBY30629.1 - 0.054 13.5 4.6 0.13 12.3 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CBY30629.1 - 0.068 13.3 3.2 0.19 11.9 3.2 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 CBY30629.1 - 0.41 10.6 3.6 0.85 9.6 3.6 1.6 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.13 CBY30629.1 - 0.45 10.5 12.0 0.59 10.1 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Collagen PF01391.18 CBY30631.1 - 1.7e-40 136.6 172.2 4e-08 32.9 23.7 6.3 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) C1q PF00386.21 CBY30631.1 - 6.3e-08 32.9 0.1 9.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 C1q domain PPC PF04151.15 CBY30631.1 - 0.031 15.4 0.3 0.058 14.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain AAA_12 PF13087.6 CBY30632.1 - 1.1e-43 149.2 0.0 2.3e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY30632.1 - 1.4e-37 129.9 0.5 8.1e-21 75.0 0.0 4.0 2 2 1 3 3 2 2 AAA domain AAA_30 PF13604.6 CBY30632.1 - 5.3e-17 62.2 0.1 6.6e-16 58.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY30632.1 - 1.9e-10 41.3 0.0 6.8e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBY30632.1 - 2e-09 37.6 0.2 0.03 14.0 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-AN1 PF01428.16 CBY30632.1 - 5.6e-09 36.0 11.4 5.7e-09 36.0 7.5 2.4 2 0 0 2 2 2 1 AN1-like Zinc finger AAA_16 PF13191.6 CBY30632.1 - 3.8e-05 24.1 0.0 0.00024 21.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.14 CBY30632.1 - 5.2e-05 23.2 0.3 5.2e-05 23.2 0.3 2.5 3 1 0 3 3 1 1 Helicase AAA_22 PF13401.6 CBY30632.1 - 7.9e-05 23.0 0.5 0.00046 20.5 0.1 2.7 3 1 0 3 3 1 1 AAA domain AAA PF00004.29 CBY30632.1 - 7.9e-05 23.1 0.0 0.00028 21.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CBY30632.1 - 0.00026 20.3 0.1 0.02 14.2 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 CBY30632.1 - 0.00042 20.1 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain XAF1_C PF18608.1 CBY30632.1 - 0.00052 19.5 0.5 0.028 13.9 0.4 2.5 2 0 0 2 2 2 1 XIAP-associated factor 1 C-terminal domain RuvB_N PF05496.12 CBY30632.1 - 0.00061 19.6 0.3 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CBY30632.1 - 0.0027 17.7 0.1 0.01 15.8 0.0 2.1 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CBY30632.1 - 0.0029 17.1 0.0 0.096 12.1 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 CBY30632.1 - 0.0029 17.3 0.0 0.0092 15.7 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 CBY30632.1 - 0.0085 15.2 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.13 CBY30632.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 CBY30632.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CBY30632.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBY30632.1 - 0.024 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CBY30632.1 - 0.025 14.7 0.0 0.091 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBY30632.1 - 0.03 14.3 0.0 0.095 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY30632.1 - 0.036 14.4 0.4 0.35 11.3 0.0 2.9 3 1 0 3 3 2 0 RNA helicase zf_UBZ PF18439.1 CBY30632.1 - 0.044 13.4 4.2 0.3 10.7 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GARS_N PF02844.15 CBY30632.1 - 0.062 14.1 0.0 0.31 11.8 0.0 2.2 2 0 0 2 2 1 0 Phosphoribosylglycinamide synthetase, N domain RsgA_GTPase PF03193.16 CBY30632.1 - 0.079 12.9 1.6 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CBY30632.1 - 0.095 12.2 0.1 0.41 10.1 0.0 2.1 3 0 0 3 3 2 0 P-loop containing dynein motor region TsaE PF02367.17 CBY30632.1 - 0.096 12.7 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CBY30632.1 - 0.1 13.1 0.2 2.5 8.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBY30632.1 - 0.11 12.6 2.1 0.25 11.4 0.0 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_29 PF13555.6 CBY30632.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY30632.1 - 0.12 12.9 1.3 0.29 11.7 0.0 2.4 2 1 0 2 2 1 0 ABC transporter zf-UBP PF02148.19 CBY30632.1 - 0.89 9.9 3.8 2.4 8.6 3.8 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2318 PF10080.9 CBY30632.1 - 1.5 9.0 4.4 0.89 9.7 0.6 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) SH2_2 PF14633.6 CBY30633.1 - 0.043 13.2 0.7 0.045 13.2 0.7 1.1 1 0 0 1 1 1 0 SH2 domain CIDR1_gamma PF18562.1 CBY30633.1 - 1 9.5 6.5 2.3 8.4 6.5 1.7 1 1 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma Glyco_tranf_2_3 PF13641.6 CBY30634.1 - 3.8e-21 76.0 0.1 6.4e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_6 PF01341.17 CBY30634.1 - 1.9e-16 60.7 0.1 4.3e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glyco_trans_2_3 PF13632.6 CBY30634.1 - 2.2e-15 57.1 2.8 2.2e-15 57.1 2.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CBY30634.1 - 4e-14 52.8 0.1 7e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 CBY30634.1 - 1.6e-07 30.2 12.5 5.2e-06 25.3 8.7 2.6 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 CBY30634.1 - 1.7e-07 30.9 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 ZapB PF06005.12 CBY30636.1 - 0.02 15.3 2.4 0.036 14.5 2.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 CBY30636.1 - 0.028 14.5 2.2 0.054 13.6 1.5 1.8 1 1 1 2 2 2 0 bZIP transcription factor YabA PF06156.13 CBY30636.1 - 0.029 15.0 2.7 0.054 14.1 2.7 1.4 1 1 1 2 2 2 0 Initiation control protein YabA NRBF2 PF08961.10 CBY30636.1 - 0.032 13.8 2.3 0.046 13.3 2.3 1.4 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator PCRF PF03462.18 CBY30636.1 - 0.068 13.0 2.4 0.082 12.8 2.4 1.1 1 0 0 1 1 1 0 PCRF domain bZIP_2 PF07716.15 CBY30636.1 - 0.084 13.0 2.0 0.12 12.5 1.5 1.5 1 1 0 1 1 1 0 Basic region leucine zipper PCI PF01399.27 CBY30638.1 - 6.7e-13 49.1 0.7 6.7e-13 49.1 0.7 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 CBY30638.1 - 0.0048 16.6 0.4 0.016 14.9 0.4 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 CBY30638.1 - 0.074 13.6 0.1 0.78 10.3 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat CSN4_RPN5_eIF3a PF18420.1 CBY30638.1 - 0.14 12.3 2.0 0.22 11.7 0.4 2.2 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain FNIP_M PF14637.6 CBY30638.1 - 3 7.8 6.9 35 4.3 0.0 3.6 3 1 1 4 4 4 0 Folliculin-interacting protein middle domain PHD PF00628.29 CBY30639.1 - 8.2e-11 41.6 25.2 4.6e-07 29.6 8.1 3.2 3 0 0 3 3 3 2 PHD-finger PLU-1 PF08429.11 CBY30639.1 - 1.1e-09 38.0 5.2 1.7e-06 27.5 0.2 2.5 2 1 0 2 2 2 2 PLU-1-like protein Polyhedrin PF00738.18 CBY30639.1 - 0.13 11.5 0.4 0.32 10.3 0.4 1.5 1 0 0 1 1 1 0 Polyhedrin zf-CW PF07496.15 CBY30639.1 - 0.82 9.8 10.3 0.25 11.4 4.0 3.3 3 0 0 3 3 3 0 CW-type Zinc Finger JmjC PF02373.22 CBY30640.1 - 5.4e-39 133.2 0.6 1.1e-38 132.1 0.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CBY30640.1 - 3.4e-16 58.9 2.5 4.8e-16 58.4 0.8 2.3 2 0 0 2 2 2 1 jmjN domain ARID PF01388.21 CBY30640.1 - 4.4e-16 59.3 0.0 1.5e-13 51.2 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PLU-1 PF08429.11 CBY30640.1 - 2.9e-09 36.6 8.2 4.3e-06 26.1 0.4 2.5 2 1 1 3 3 3 2 PLU-1-like protein Remorin_C PF03763.13 CBY30640.1 - 0.0018 18.1 1.4 0.0036 17.1 0.1 2.0 2 0 0 2 2 2 1 Remorin, C-terminal region PHD_Oberon PF07227.11 CBY30640.1 - 0.91 9.4 4.8 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein Bac_RepA_C PF18008.1 CBY30640.1 - 2.1 8.7 8.1 4.2 7.8 0.4 3.4 3 0 0 3 3 3 0 Replication initiator protein A C-terminal domain Laminin_I PF06008.14 CBY30640.1 - 2.5 7.7 7.6 52 3.4 7.3 2.4 1 1 0 1 1 1 0 Laminin Domain I CSTF2_hinge PF14327.6 CBY30641.1 - 0.012 16.1 4.5 0.097 13.1 0.5 3.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 FHA PF00498.26 CBY30642.1 - 8.8e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain SSF PF00474.17 CBY30643.1 - 7.7e-18 64.5 2.0 9.3e-18 64.3 2.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Kringle PF00051.18 CBY30644.1 - 3.2e-44 149.1 15.4 7.2e-22 77.5 6.0 2.8 2 0 0 2 2 2 2 Kringle domain FXa_inhibition PF14670.6 CBY30644.1 - 0.00088 19.5 12.5 0.0089 16.3 12.5 2.9 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site HTH_48 PF17906.1 CBY30644.1 - 0.17 12.0 0.3 16 5.7 0.1 2.8 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Kringle PF00051.18 CBY30645.1 - 1.3e-15 57.4 1.6 1.3e-15 57.4 1.6 1.0 1 0 0 1 1 1 1 Kringle domain Toxin_5 PF05294.13 CBY30645.1 - 0.45 11.0 3.6 0.36 11.3 1.9 1.9 2 1 0 2 2 2 0 Scorpion short toxin CUB PF00431.20 CBY30646.1 - 3.5e-13 49.9 0.8 2.7e-10 40.5 0.8 2.7 1 1 0 1 1 1 1 CUB domain IMUP PF15761.5 CBY30646.1 - 0.36 11.5 3.8 0.72 10.6 3.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3524 PF12038.8 CBY30647.1 - 4.9e-60 202.2 0.3 1.2e-59 200.9 0.1 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 CBY30647.1 - 3.1e-09 36.6 0.0 6.3e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Gla PF00594.20 CBY30647.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Methyltransf_32 PF13679.6 CBY30651.1 - 1.1e-17 64.4 1.3 3.6e-17 62.8 0.8 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY30651.1 - 9.1e-06 26.3 0.0 4.1e-05 24.2 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY30651.1 - 5.6e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY30651.1 - 8e-05 22.3 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 CBY30651.1 - 0.00055 19.4 0.1 0.00084 18.8 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 CBY30651.1 - 0.0011 19.7 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY30651.1 - 0.0014 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY30651.1 - 0.0023 17.9 0.2 0.0065 16.4 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY30651.1 - 0.015 15.9 0.0 0.038 14.6 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.20 CBY30651.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 CBY30651.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.18 CBY30651.1 - 0.025 14.5 0.3 0.044 13.7 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.19 CBY30651.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M14 PF00246.24 CBY30652.1 - 1.7e-64 218.5 0.0 2.3e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY30652.1 - 9.5e-06 24.9 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Glyco_hydro_18 PF00704.28 CBY30653.1 - 6.8e-85 285.5 1.5 1e-84 285.0 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY30653.1 - 1.6e-20 73.0 27.1 1.7e-12 47.3 9.6 2.8 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Lysyl_oxidase PF01186.17 CBY30654.1 - 6.8e-78 261.0 5.7 9.7e-78 260.5 5.7 1.2 1 0 0 1 1 1 1 Lysyl oxidase Sulfotransfer_1 PF00685.27 CBY30655.1 - 4.9e-17 62.3 0.4 1.7e-16 60.5 0.4 1.7 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30655.1 - 1.6e-09 38.5 0.0 2.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY30655.1 - 0.0018 18.2 0.1 0.0021 18.0 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase family E1-E2_ATPase PF00122.20 CBY30656.1 - 2.8e-46 157.3 2.3 2.8e-46 157.3 2.3 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY30656.1 - 1.6e-43 148.5 1.1 1.6e-43 148.5 1.1 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CBY30656.1 - 2.8e-25 88.2 0.0 5.3e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY30656.1 - 5.7e-19 69.2 0.3 1.1e-15 58.5 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBY30656.1 - 8.4e-13 47.8 0.0 1.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY30656.1 - 3.8e-07 30.1 1.0 0.00077 19.3 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY30656.1 - 0.013 15.9 0.1 0.099 13.0 0.1 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase O-FucT PF10250.9 CBY30657.1 - 8.6e-10 38.8 0.2 1.8e-09 37.8 0.2 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aminotran_1_2 PF00155.21 CBY30658.1 - 5.9e-43 147.4 0.0 7.5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY30658.1 - 0.0054 16.0 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyr_redox_2 PF07992.14 CBY30658.1 - 0.092 12.0 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KIAA1430 PF13879.6 CBY30659.1 - 2.9e-28 98.6 9.9 2.9e-28 98.6 9.9 2.4 3 0 0 3 3 3 1 KIAA1430 homologue Mitoc_L55 PF09776.9 CBY30659.1 - 1.2 8.9 7.9 0.44 10.3 1.4 2.5 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L55 Cadherin_3 PF16184.5 CBY30660.1 - 5.7e-13 48.8 0.0 0.005 16.8 0.0 4.7 4 0 0 4 4 4 3 Cadherin-like Furin-like_2 PF15913.5 CBY30660.1 - 3.1e-09 36.9 50.6 6.7e-05 23.0 11.4 3.4 1 1 2 3 3 3 3 Furin-like repeat, cysteine-rich VSP PF03302.13 CBY30660.1 - 0.0027 16.6 46.8 0.074 11.9 10.6 3.6 1 1 2 3 3 3 3 Giardia variant-specific surface protein Calx-beta PF03160.14 CBY30661.1 - 1.6e-54 182.2 22.9 2.4e-14 53.3 0.2 6.4 5 1 1 6 6 6 5 Calx-beta domain Cadherin_3 PF16184.5 CBY30661.1 - 1.1e-24 86.5 2.5 1.1e-17 64.0 0.4 4.0 4 0 0 4 4 4 2 Cadherin-like DUF4843 PF16132.5 CBY30661.1 - 0.0035 16.9 1.4 4.3 6.9 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4843) CDC45 PF02724.14 CBY30662.1 - 0.22 9.8 5.8 0.23 9.7 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBY30662.1 - 0.24 10.1 1.1 0.27 10.0 1.1 1.2 1 0 0 1 1 1 0 Presenilin Troponin PF00992.20 CBY30664.1 - 2.3e-35 121.8 12.0 3e-35 121.5 12.0 1.0 1 0 0 1 1 1 1 Troponin Tup_N PF08581.10 CBY30664.1 - 0.02 15.2 0.9 0.055 13.8 0.3 2.1 2 0 0 2 2 2 0 Tup N-terminal Cauli_DNA-bind PF03310.13 CBY30664.1 - 0.026 14.6 4.4 0.027 14.6 3.1 1.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Fes1 PF08609.10 CBY30664.1 - 0.15 13.0 3.8 5.4 8.0 3.8 2.2 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF1690 PF07956.11 CBY30664.1 - 0.53 10.7 7.8 0.83 10.1 7.8 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DivIC PF04977.15 CBY30664.1 - 2.3 8.0 7.3 7.3 6.4 3.1 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF3978 PF13123.6 CBY30665.1 - 0.038 13.7 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) Endomucin PF07010.12 CBY30666.1 - 0.23 11.4 25.5 0.34 10.9 25.5 1.2 1 0 0 1 1 1 0 Endomucin PRCC PF10253.9 CBY30666.1 - 0.61 10.8 8.1 0.75 10.5 8.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4446 PF14584.6 CBY30667.1 - 0.00028 20.9 0.3 0.00051 20.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Fungal_TACC PF12709.7 CBY30667.1 - 0.0012 19.3 1.1 0.0058 17.1 1.2 2.0 2 1 0 2 2 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins KASH_CCD PF14662.6 CBY30667.1 - 0.0074 16.1 2.3 0.012 15.4 2.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Kelch_6 PF13964.6 CBY30667.1 - 0.011 16.0 0.2 20 5.6 0.0 3.5 2 1 1 3 3 3 0 Kelch motif NKWYS PF10364.9 CBY30667.1 - 0.014 15.5 2.2 0.026 14.6 2.2 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Kelch_4 PF13418.6 CBY30667.1 - 0.014 15.3 2.5 17 5.6 0.0 3.8 3 1 0 3 3 3 0 Galactose oxidase, central domain DivIC PF04977.15 CBY30667.1 - 0.015 15.0 1.6 0.2 11.4 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 CBY30667.1 - 0.018 15.1 7.8 0.094 12.8 3.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CBY30667.1 - 0.023 15.1 4.2 0.064 13.7 4.2 1.8 1 1 0 1 1 1 0 Cell division protein ZapB Kelch_5 PF13854.6 CBY30667.1 - 0.024 14.7 0.1 26 5.0 0.1 3.4 3 0 0 3 3 3 0 Kelch motif HALZ PF02183.18 CBY30667.1 - 0.032 14.5 5.0 0.058 13.6 0.9 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CBY30667.1 - 0.067 13.3 7.4 1.8 8.8 3.6 2.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 RPW8 PF05659.11 CBY30667.1 - 0.074 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SIKE PF05769.11 CBY30667.1 - 0.16 11.9 1.1 11 5.9 0.1 2.3 2 0 0 2 2 2 0 SIKE family DMPK_coil PF08826.10 CBY30667.1 - 0.16 12.1 1.8 0.4 10.8 1.8 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like Cep57_CLD_2 PF14197.6 CBY30667.1 - 0.42 10.7 7.0 2.1 8.5 7.0 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 YabA PF06156.13 CBY30667.1 - 0.45 11.2 4.4 8.1 7.1 1.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Mto2_bdg PF12808.7 CBY30667.1 - 0.68 10.3 7.0 0.38 11.1 1.1 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Kelch_1 PF01344.25 CBY30667.1 - 0.75 9.4 2.0 6.1 6.5 0.0 3.3 4 1 0 4 4 4 0 Kelch motif Trypsin PF00089.26 CBY30668.1 - 1.8e-29 103.2 0.1 2.6e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kelch_2 PF07646.15 CBY30668.1 - 2.1e-05 24.3 0.2 0.02 14.9 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY30668.1 - 0.0025 17.8 0.3 0.02 14.9 0.2 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.15 CBY30668.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Kelch_5 PF13854.6 CBY30668.1 - 0.072 13.1 0.6 0.35 10.9 0.0 2.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY30668.1 - 0.083 13.2 0.0 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 Kelch motif Phospholip_A2_1 PF00068.19 CBY30670.1 - 4.6e-16 59.3 2.1 8.5e-16 58.4 2.1 1.5 1 0 0 1 1 1 1 Phospholipase A2 EGF_3 PF12947.7 CBY30671.1 - 3e-09 36.9 60.4 6.5e-05 23.0 11.2 6.7 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.15 CBY30671.1 - 1.2e-07 31.9 73.5 0.00023 21.3 14.4 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain EGF PF00008.27 CBY30671.1 - 0.0027 18.0 50.8 0.021 15.1 7.4 5.6 5 0 0 5 5 5 4 EGF-like domain Ldl_recept_a PF00057.18 CBY30671.1 - 0.012 15.8 0.4 0.012 15.8 0.4 7.2 8 0 0 8 8 8 0 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY30671.1 - 1 10.1 41.6 0.27 11.9 1.7 6.4 5 1 0 5 5 5 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY30673.1 - 1.3e-12 47.7 23.5 4.8e-08 33.1 11.3 5.0 4 1 2 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.7 CBY30673.1 - 1.2e-09 37.9 23.5 0.00053 19.9 0.5 4.6 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY30673.1 - 0.026 14.8 6.3 0.026 14.8 6.3 4.7 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY30673.1 - 9.4 6.5 33.2 0.35 11.1 7.5 5.1 2 2 2 4 4 4 0 EGF domain Troponin PF00992.20 CBY30674.1 - 9.5e-35 119.8 17.5 1.2e-34 119.5 17.5 1.0 1 0 0 1 1 1 1 Troponin LXG PF04740.12 CBY30674.1 - 0.036 13.8 1.7 0.052 13.2 1.4 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily SIN1_PH PF16979.5 CBY30674.1 - 0.092 13.0 1.5 0.15 12.3 1.5 1.6 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SLATT_fungal PF18142.1 CBY30674.1 - 0.16 12.0 0.6 0.29 11.1 0.6 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain GLTSCR1 PF15249.6 CBY30674.1 - 0.16 12.4 4.1 0.32 11.4 4.0 1.7 1 1 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein eIF3_N PF09440.10 CBY30674.1 - 0.5 10.8 6.8 2.2 8.7 5.2 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DivIC PF04977.15 CBY30674.1 - 0.58 10.0 8.1 0.74 9.6 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CBY30674.1 - 1.4 9.4 9.0 0.077 13.4 2.2 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MRPL52 PF18699.1 CBY30674.1 - 8.6 6.6 12.5 9.3 6.5 1.6 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 Astacin PF01400.24 CBY30675.1 - 4.1e-26 91.8 0.0 6.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY30675.1 - 2.6e-06 27.5 7.5 2.6e-06 27.5 7.5 4.9 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A Kelch_2 PF07646.15 CBY30676.1 - 0.03 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Kelch motif GST_N_2 PF13409.6 CBY30678.1 - 0.068 13.5 0.0 0.073 13.4 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ets PF00178.22 CBY30679.1 - 1.2e-36 125.0 1.9 2e-36 124.3 1.9 1.3 1 0 0 1 1 1 1 Ets-domain RNA_pol_Rpc34 PF05158.12 CBY30679.1 - 0.12 11.8 2.7 0.12 11.8 1.8 1.5 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit Kelch_6 PF13964.6 CBY30680.1 - 3.7e-10 39.7 0.8 0.0036 17.5 0.2 3.8 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CBY30680.1 - 2.1e-06 27.7 1.8 0.018 15.1 0.2 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY30680.1 - 5.8e-05 22.6 0.4 0.095 12.3 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY30680.1 - 0.00014 21.7 0.7 0.82 9.7 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY30680.1 - 0.014 15.4 8.1 0.32 11.0 0.1 4.4 5 0 0 5 5 5 0 Kelch motif Acyl-CoA_dh_1 PF00441.24 CBY30681.1 - 2.1e-38 131.9 2.8 3.4e-38 131.2 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY30681.1 - 4e-27 95.1 0.0 1.2e-26 93.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY30681.1 - 1.1e-23 83.2 0.0 2.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY30681.1 - 4.7e-15 56.0 0.3 6.6e-15 55.6 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF905 PF06006.12 CBY30682.1 - 0.03 14.3 0.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) CUB PF00431.20 CBY30683.1 - 4.6e-13 49.5 0.5 1.1e-11 45.0 0.0 2.2 1 1 1 2 2 2 2 CUB domain CUB PF00431.20 CBY30685.1 - 4.6e-13 49.5 0.5 1.1e-11 45.0 0.0 2.2 1 1 1 2 2 2 2 CUB domain SUR7 PF06687.12 CBY30688.1 - 0.025 14.2 0.5 0.026 14.2 0.5 1.0 1 0 0 1 1 1 0 SUR7/PalI family Plasmod_dom_1 PF09715.10 CBY30688.1 - 0.058 13.5 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Kinesin PF00225.23 CBY30689.1 - 3.9e-101 338.3 0.4 6.3e-101 337.6 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY30689.1 - 2.5e-21 76.2 0.7 1.2e-20 73.9 0.2 2.2 2 0 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 CBY30689.1 - 1.5e-06 28.5 2.1 1.6e-06 28.4 0.3 2.0 2 0 0 2 2 2 1 Kinesin-associated FHA PF00498.26 CBY30689.1 - 3.4e-06 27.3 0.0 1.3e-05 25.5 0.0 2.1 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 CBY30689.1 - 0.00033 21.0 2.2 0.00038 20.8 0.5 2.1 2 0 0 2 2 2 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 CBY30689.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain UPF0242 PF06785.11 CBY30689.1 - 0.018 15.2 1.0 0.037 14.1 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 CBY30689.1 - 0.23 11.2 2.0 0.84 9.4 2.0 1.9 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF87 PF01935.17 CBY30689.1 - 0.48 10.5 3.2 18 5.3 0.3 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4897 PF16238.5 CBY30690.1 - 0.062 13.1 0.3 0.094 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) Ank_2 PF12796.7 CBY30691.1 - 1.8e-21 76.5 0.9 2.6e-09 37.5 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY30691.1 - 1.2e-17 64.1 0.0 7.4e-05 23.2 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY30691.1 - 2.6e-09 36.6 0.0 0.24 12.1 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY30691.1 - 1.4e-07 31.6 0.1 0.004 17.4 0.2 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY30691.1 - 8.6e-05 22.8 0.1 0.96 10.0 0.1 4.7 5 1 0 5 5 5 1 Ankyrin repeat DUF1493 PF07377.12 CBY30692.1 - 0.29 11.6 3.8 0.14 12.6 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1493) YojJ PF10372.9 CBY30694.1 - 0.11 12.6 3.0 0.16 12.0 3.0 1.4 1 1 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus API5 PF05918.11 CBY30696.1 - 0.0051 15.7 7.4 0.01 14.7 6.2 1.9 1 1 1 2 2 2 1 Apoptosis inhibitory protein 5 (API5) BTV_NS2 PF04514.12 CBY30696.1 - 0.39 9.5 4.4 0.59 8.9 4.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1640 PF07798.11 CBY30696.1 - 9.3 6.3 17.4 0.51 10.4 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) zf-rbx1 PF12678.7 CBY30697.1 - 9.2e-07 29.1 5.5 1.6e-06 28.3 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBY30697.1 - 9.8e-07 29.0 5.9 9.8e-07 29.0 5.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY30697.1 - 3.5e-06 26.8 3.6 8.2e-06 25.6 3.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY30697.1 - 9.6e-06 25.6 4.0 1.7e-05 24.8 4.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBY30697.1 - 9.7e-05 22.1 1.9 9.7e-05 22.1 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY30697.1 - 0.00011 22.1 5.2 0.00024 21.0 5.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY30697.1 - 0.0029 17.6 7.7 0.0094 16.0 2.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY30697.1 - 0.017 15.0 4.2 0.017 15.0 4.2 1.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY30697.1 - 0.031 14.1 4.9 0.14 12.0 4.8 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fibrillin_U_N PF18193.1 CBY30697.1 - 0.069 13.3 1.0 0.14 12.3 1.0 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain zf-C3HC4_4 PF15227.6 CBY30697.1 - 0.08 13.1 1.0 0.23 11.7 1.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CBY30697.1 - 0.14 12.3 5.3 2.2 8.5 5.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 CBY30697.1 - 0.38 10.5 8.7 0.16 11.7 5.0 2.3 2 1 0 2 2 2 0 RING-like zinc finger zf-UDP PF14569.6 CBY30697.1 - 0.74 10.0 6.9 2.5 8.3 6.2 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger ArAE_2_N PF10337.9 CBY30697.1 - 1.3 7.9 8.1 0.28 10.2 0.2 2.2 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal DUF3796 PF12676.7 CBY30697.1 - 2.7 8.5 8.1 1.9 8.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) adh_short PF00106.25 CBY30698.1 - 1.9e-26 92.7 0.1 3.1e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY30698.1 - 1e-22 80.8 0.2 1.4e-22 80.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY30698.1 - 1.4e-06 28.4 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 CBY30698.1 - 0.028 14.6 0.1 0.047 13.9 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 CBY30698.1 - 0.053 12.7 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PriC PF07445.12 CBY30700.1 - 0.061 13.3 0.3 3 7.7 0.0 2.8 2 1 1 3 3 3 0 Primosomal replication protein priC EF-hand_1 PF00036.32 CBY30701.1 - 3.7e-15 54.3 5.3 4.2e-06 25.9 0.1 3.3 2 1 1 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY30701.1 - 8e-13 47.2 2.7 1.7e-05 24.4 0.1 3.4 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY30701.1 - 1e-11 45.1 2.5 3.7e-11 43.3 0.8 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY30701.1 - 2.7e-11 43.2 4.8 0.00019 21.2 0.1 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY30701.1 - 3.8e-11 42.0 4.1 0.00012 21.4 0.1 2.8 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CBY30701.1 - 0.005 17.1 0.3 0.012 15.9 0.3 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5508 PF17621.2 CBY30701.1 - 0.029 13.5 0.4 0.047 12.8 0.3 1.3 1 1 1 2 2 2 0 Family of unknown function (DUF5508) PRD PF00874.20 CBY30701.1 - 0.044 14.1 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 PRD domain Xylo_C PF12529.8 CBY30701.1 - 0.045 13.4 0.0 0.048 13.3 0.0 1.1 1 0 0 1 1 1 0 Xylosyltransferase C terminal RecG_N PF17190.4 CBY30701.1 - 0.053 14.2 1.5 0.091 13.5 0.2 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain MctB PF11382.8 CBY30702.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Glycos_transf_2 PF00535.26 CBY30703.1 - 2.1e-23 83.0 0.0 3.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY30703.1 - 2.7e-07 30.1 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY30703.1 - 0.072 12.5 0.1 0.86 9.0 0.0 2.3 2 1 0 2 2 2 0 Glycosyltransferase like family 2 SVS_QK PF10578.9 CBY30703.1 - 0.13 12.9 0.4 0.7 10.6 0.4 2.3 1 0 0 1 1 1 0 Seminal vesicle protein repeat Kelch_5 PF13854.6 CBY30704.1 - 0.00016 21.6 0.8 0.51 10.4 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY30704.1 - 0.00047 20.0 6.0 0.052 13.5 0.8 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY30704.1 - 0.0011 18.5 0.5 1.9 8.1 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY30704.1 - 0.0021 18.0 1.5 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY30704.1 - 0.0036 17.6 3.8 2.2 8.7 0.3 3.1 2 1 1 3 3 3 2 Kelch motif FXa_inhibition PF14670.6 CBY30705.1 - 0.00011 22.4 8.3 0.00043 20.5 8.3 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site PorP_SprF PF11751.8 CBY30705.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IX secretion system membrane protein PorP/SprF Glycos_transf_2 PF00535.26 CBY30706.1 - 8.3e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY30706.1 - 3.3e-07 29.9 0.1 6.4e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY30706.1 - 0.096 12.1 0.0 1.1 8.7 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase like family 2 SVS_QK PF10578.9 CBY30706.1 - 0.21 12.2 0.4 0.78 10.5 0.4 2.0 1 0 0 1 1 1 0 Seminal vesicle protein repeat adh_short_C2 PF13561.6 CBY30707.1 - 1.8e-57 194.6 1.8 2.2e-57 194.3 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY30707.1 - 2.8e-49 167.2 0.2 3.5e-49 166.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY30707.1 - 1.7e-13 50.9 0.3 2.7e-13 50.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY30707.1 - 6.9e-06 25.7 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY30707.1 - 7e-05 22.8 0.6 0.00018 21.5 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY30707.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 CBY30707.1 - 0.0068 16.7 0.1 0.0068 16.7 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 CBY30707.1 - 0.01 15.2 0.1 0.045 13.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CBY30707.1 - 0.083 12.8 0.1 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDPD PF03009.17 CBY30709.1 - 2.4e-40 138.9 0.0 3.4e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Helicase_PWI PF18149.1 CBY30710.1 - 0.095 12.9 4.6 0.23 11.6 0.2 3.0 3 0 0 3 3 3 0 N-terminal helicase PWI domain KfrA_N PF11740.8 CBY30710.1 - 0.1 13.3 0.0 11 6.7 0.0 2.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term UNC-93 PF05978.16 CBY30711.1 - 4.2e-23 81.8 8.3 4.2e-23 81.8 8.3 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 RabGAP-TBC PF00566.18 CBY30712.1 - 1.2e-33 116.6 4.0 6.7e-31 107.6 0.8 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TFIIE_alpha PF02002.17 CBY30713.1 - 3.1e-17 62.4 1.2 6.3e-17 61.4 1.2 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 CBY30713.1 - 4.2e-08 33.4 9.0 1.3e-07 31.9 9.0 2.0 1 1 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.12 CBY30713.1 - 5.3e-06 25.9 1.7 1.5e-05 24.4 1.7 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Elf1 PF05129.13 CBY30713.1 - 0.082 13.0 1.0 0.16 12.0 1.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zona_pellucida PF00100.23 CBY30714.1 - 2e-23 83.5 6.8 3.5e-23 82.7 6.8 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY30714.1 - 0.00025 21.3 12.7 0.00081 19.6 12.7 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site OppC_N PF12911.7 CBY30715.1 - 1.4 9.0 12.5 2 8.5 1.4 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ATP1G1_PLM_MAT8 PF02038.16 CBY30715.1 - 1.9 8.0 6.0 4.2 6.9 0.2 2.9 1 1 0 2 2 2 0 ATP1G1/PLM/MAT8 family CAP_C PF08603.11 CBY30716.1 - 6.1e-40 136.4 7.8 6.1e-40 136.4 7.8 1.9 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CBY30716.1 - 0.0001 21.9 1.1 0.00022 20.9 0.5 1.9 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CBY30716.1 - 0.078 12.7 3.1 0.18 11.6 3.1 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C Siah-Interact_N PF09032.11 CBY30716.1 - 0.87 9.9 5.5 0.53 10.6 2.1 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal ApoLp-III PF07464.11 CBY30717.1 - 0.001 19.2 3.3 0.0016 18.5 2.7 1.7 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YfdX PF10938.8 CBY30717.1 - 0.0036 17.2 0.3 0.084 12.8 0.1 2.2 2 0 0 2 2 2 1 YfdX protein Vps53_N PF04100.12 CBY30717.1 - 0.0048 15.9 2.0 0.0067 15.4 2.0 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal RE_HindIII PF09518.10 CBY30717.1 - 0.0056 16.0 3.0 0.058 12.6 2.0 2.0 1 1 1 2 2 2 1 HindIII restriction endonuclease THOC7 PF05615.13 CBY30717.1 - 0.0073 16.6 3.6 0.011 16.0 3.6 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 ISG65-75 PF11727.8 CBY30717.1 - 0.0088 15.3 2.0 0.0088 15.3 2.0 1.8 2 0 0 2 2 2 1 Invariant surface glycoprotein MCPsignal PF00015.21 CBY30717.1 - 0.013 15.4 0.9 0.018 14.8 0.9 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 CBY30717.1 - 0.088 12.8 5.3 0.038 14.0 2.6 1.7 2 1 0 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 CBY30717.1 - 0.096 13.4 6.0 0.99 10.1 2.9 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mis14 PF08641.12 CBY30717.1 - 0.11 12.8 6.1 0.23 11.8 3.5 2.1 1 1 0 2 2 2 0 Kinetochore protein Mis14 like ECH_2 PF16113.5 CBY30717.1 - 0.12 11.9 2.1 0.14 11.6 1.4 1.5 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase REC1 PF18501.1 CBY30717.1 - 0.15 11.9 5.0 0.088 12.7 2.2 1.8 1 1 0 2 2 2 0 Alpha helical recognition lobe domain DUF1043 PF06295.12 CBY30717.1 - 0.18 11.8 4.6 1 9.3 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) ZnuA PF01297.17 CBY30717.1 - 0.23 10.8 2.4 0.31 10.4 2.4 1.3 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic YscO-like PF16789.5 CBY30717.1 - 0.24 11.4 9.4 0.03 14.3 4.8 1.8 2 0 0 2 2 2 0 YscO-like protein DUF948 PF06103.11 CBY30717.1 - 0.26 11.6 2.5 2.3 8.5 0.2 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) 5_nucleotid PF05761.14 CBY30717.1 - 0.3 10.0 3.6 0.41 9.5 3.6 1.1 1 0 0 1 1 1 0 5' nucleotidase family Phasin PF05597.11 CBY30717.1 - 0.59 10.1 5.6 0.67 10.0 2.4 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF5082 PF16888.5 CBY30717.1 - 0.94 9.8 7.4 2 8.7 3.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 CBY30717.1 - 3.2 8.3 10.1 9.6 6.7 10.1 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF883 PF05957.13 CBY30717.1 - 3.4 8.3 6.6 13 6.4 3.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Galactosyl_T PF01762.21 CBY30718.1 - 7.3e-36 123.8 0.5 1.5e-35 122.8 0.3 1.6 2 0 0 2 2 2 1 Galactosyltransferase DUF2205 PF10224.9 CBY30718.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Short coiled-coil protein Sugar_tr PF00083.24 CBY30719.1 - 6.8e-24 84.5 16.5 7.6e-19 67.9 10.9 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY30719.1 - 8.9e-15 54.5 17.1 1.1e-07 31.1 3.3 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 CBY30719.1 - 9.5e-06 25.1 0.9 2.1e-05 24.0 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Kunitz_BPTI PF00014.23 CBY30720.1 - 4.6e-16 58.8 1.5 5.1e-16 58.6 1.5 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF3471 PF11954.8 CBY30721.1 - 0.17 12.4 0.0 0.19 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Beta_elim_lyase PF01212.21 CBY30722.1 - 1.6e-67 227.9 0.0 1.9e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CBY30722.1 - 5.8e-07 29.0 0.0 7.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBY30722.1 - 1.4e-05 24.2 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 CBY30722.1 - 0.0013 17.5 0.0 0.0022 16.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CBY30722.1 - 0.0016 17.8 0.1 0.0021 17.4 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TMP_2 PF06791.13 CBY30722.1 - 0.082 12.6 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein Gal-3-0_sulfotr PF06990.11 CBY30723.1 - 1e-67 228.8 0.0 1.3e-67 228.5 0.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase PHINT_rpt PF14882.6 CBY30723.1 - 0.074 13.3 4.7 6 7.2 0.0 3.2 3 0 0 3 3 3 0 Phage-integrase repeat unit Sulfotransfer_3 PF13469.6 CBY30723.1 - 0.12 12.7 0.1 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family DNA_pol_phi PF04931.13 CBY30724.1 - 1.6 6.8 5.4 2 6.4 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi VWA_3 PF13768.6 CBY30725.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Synaptobrevin PF00957.21 CBY30725.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.8 4 0 0 4 4 4 0 Synaptobrevin Sulfotransfer_4 PF17784.1 CBY30727.1 - 9e-43 146.6 0.1 1.4e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30727.1 - 0.093 13.1 0.1 0.3 11.5 0.1 1.9 1 1 1 2 2 2 0 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY30728.1 - 6.7e-44 150.3 0.2 8.5e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30728.1 - 0.026 14.9 0.0 0.067 13.6 0.0 1.8 2 0 0 2 2 2 0 Sulfotransferase family An_peroxidase PF03098.15 CBY30730.1 - 1.8e-126 422.8 0.0 2.5e-126 422.4 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Sulfotransfer_2 PF03567.14 CBY30730.1 - 4.5e-22 79.2 0.4 9.5e-22 78.1 0.4 1.5 1 0 0 1 1 1 1 Sulfotransferase family Y_phosphatase PF00102.27 CBY30731.1 - 1.6e-66 224.3 0.1 2.5e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY30731.1 - 0.00019 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CBY30731.1 - 0.00096 19.0 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GTP-bdg_M PF16360.5 CBY30731.1 - 0.004 17.7 1.1 0.0092 16.6 1.1 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region PTPlike_phytase PF14566.6 CBY30731.1 - 0.0059 16.7 2.9 0.022 14.9 0.0 2.9 2 2 1 3 3 3 1 Inositol hexakisphosphate zf-CCHC PF00098.23 CBY30732.1 - 0.00069 19.6 2.3 0.00069 19.6 2.3 5.3 5 1 0 5 5 5 2 Zinc knuckle DUF2170 PF09938.9 CBY30732.1 - 0.27 10.9 1.1 9.5 5.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2170) RRM_1 PF00076.22 CBY30733.1 - 0.013 15.3 0.0 0.044 13.6 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY30733.1 - 0.02 14.9 1.7 0.11 12.6 0.3 2.6 3 0 0 3 3 3 0 RNA binding motif LRR_6 PF13516.6 CBY30734.1 - 0.0059 16.6 1.6 0.82 9.9 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat OST-HTH PF12872.7 CBY30734.1 - 0.017 14.9 0.1 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 OST-HTH/LOTUS domain Lipase_GDSL_3 PF14606.6 CBY30734.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.5 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF4533 PF15047.6 CBY30734.1 - 0.66 9.5 7.2 0.12 11.9 1.1 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4533) EF-hand_6 PF13405.6 CBY30735.1 - 0.17 11.9 0.1 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Peptidase_M13 PF01431.21 CBY30737.1 - 0.2 11.2 5.0 1.1 8.8 0.2 3.3 3 0 0 3 3 3 0 Peptidase family M13 7tm_1 PF00001.21 CBY30739.1 - 8.1e-17 61.4 0.9 1.1e-16 61.0 0.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pox_A14 PF05767.12 CBY30739.1 - 2.1 8.6 6.6 1.1 9.5 1.2 2.6 1 1 2 3 3 3 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 CBY30740.1 - 2e-08 33.9 0.3 2.6e-08 33.5 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DnaJ PF00226.31 CBY30742.1 - 1.9e-11 43.9 0.7 4.1e-11 42.8 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Sulfotransfer_1 PF00685.27 CBY30743.1 - 1.4e-13 51.0 0.0 3.2e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30743.1 - 1.6e-06 28.7 0.4 0.28 11.5 0.0 3.7 3 1 1 4 4 4 3 Sulfotransferase family AgrD PF05931.11 CBY30743.1 - 0.12 12.4 0.8 0.53 10.4 0.1 2.4 2 0 0 2 2 2 0 Staphylococcal AgrD protein Nodulin-like PF06813.13 CBY30743.1 - 0.14 11.6 0.2 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 Nodulin-like MLANA PF14991.6 CBY30745.1 - 0.00024 21.3 0.3 0.0027 18.0 0.0 2.4 2 0 0 2 2 2 1 Protein melan-A DUF4446 PF14584.6 CBY30745.1 - 0.19 11.7 2.1 2.1 8.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) IPK PF03770.16 CBY30746.1 - 1.6e-26 93.4 4.4 1.1e-25 90.7 4.4 2.0 1 1 0 1 1 1 1 Inositol polyphosphate kinase KRTDAP PF15200.6 CBY30746.1 - 0.091 12.6 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Keratinocyte differentiation-associated SSF PF00474.17 CBY30747.1 - 1e-42 146.5 17.3 1.3e-42 146.1 17.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family COX14 PF14880.6 CBY30747.1 - 0.38 10.6 1.8 0.69 9.8 0.0 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Aminotran_5 PF00266.19 CBY30748.1 - 4.4e-27 95.0 0.0 7.6e-27 94.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Ldl_recept_a PF00057.18 CBY30749.1 - 8.3e-09 35.5 18.6 1.3e-08 34.9 10.9 2.4 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A TPR_2 PF07719.17 CBY30751.1 - 2.9e-11 42.6 12.9 0.13 12.4 0.1 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY30751.1 - 2.5e-07 30.9 16.4 0.0019 18.5 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY30751.1 - 1.1e-06 28.2 10.4 0.049 13.5 0.4 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.6 CBY30751.1 - 6.1e-06 25.9 0.3 6.1e-06 25.9 0.3 3.1 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 CBY30751.1 - 6.5e-06 26.5 8.3 6.7 7.8 0.2 6.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY30751.1 - 4.2e-05 23.4 6.5 0.17 12.2 0.3 5.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY30751.1 - 0.00013 22.5 9.2 0.98 10.1 0.9 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY30751.1 - 0.00014 22.3 10.5 1.3 9.5 1.5 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY30751.1 - 0.00017 21.7 10.7 0.011 15.9 0.6 5.1 5 1 1 6 6 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBY30751.1 - 0.00051 20.5 9.9 4.2 8.2 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY30751.1 - 0.00091 18.9 1.4 4.8 7.0 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 CBY30751.1 - 0.077 13.1 5.1 5.8 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ComR_TPR PF18710.1 CBY30751.1 - 0.26 10.8 3.8 4.3 6.8 0.3 2.9 2 1 1 3 3 3 0 ComR tetratricopeptide DUF2786 PF10979.8 CBY30751.1 - 0.32 10.9 5.0 3.9 7.5 0.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2786) DUF2802 PF10975.8 CBY30751.1 - 9 6.5 9.4 2.4 8.3 2.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DHR-2 PF06920.13 CBY30752.1 - 1.3e-133 446.5 3.9 1.3e-133 446.5 3.9 2.0 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 CBY30752.1 - 4.7e-33 114.7 0.6 4.4e-32 111.5 0.1 2.7 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 CBY30752.1 - 5.7e-12 46.1 0.3 2.2e-11 44.1 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) PH PF00169.29 CBY30752.1 - 1.4e-06 28.7 2.2 4.1e-06 27.2 0.5 2.7 2 0 0 2 2 2 1 PH domain Sulfotransfer_2 PF03567.14 CBY30753.1 - 3.5e-14 53.3 0.3 6.7e-14 52.4 0.3 1.5 1 0 0 1 1 1 1 Sulfotransferase family KH_1 PF00013.29 CBY30754.1 - 3e-28 97.4 3.0 4.3e-10 39.3 0.0 5.4 5 0 0 5 5 5 4 KH domain DpaA_N PF16924.5 CBY30754.1 - 0.071 13.2 0.4 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Phospholip_A2_1 PF00068.19 CBY30755.1 - 2.4e-17 63.4 8.2 2.4e-17 63.4 8.2 1.7 2 0 0 2 2 2 1 Phospholipase A2 Ldh_2 PF02615.14 CBY30756.1 - 1.5e-80 270.9 1.2 1.8e-80 270.6 1.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase EGF_CA PF07645.15 CBY30759.1 - 6.7e-15 55.0 74.0 1.9e-07 31.1 10.1 25.6 24 4 3 27 27 27 10 Calcium-binding EGF domain cEGF PF12662.7 CBY30759.1 - 1.9e-09 37.3 112.6 2.7e-06 27.2 1.5 16.3 14 1 0 14 14 14 7 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY30759.1 - 0.00053 20.1 13.6 0.0019 18.4 7.5 19.2 17 2 0 17 17 17 4 EGF domain FXa_inhibition PF14670.6 CBY30759.1 - 0.0021 18.3 1.7 0.0021 18.3 1.7 20.6 17 4 2 19 19 19 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY30759.1 - 0.0069 17.0 1.9 0.0069 17.0 1.9 22.4 23 2 0 23 23 23 5 Human growth factor-like EGF zf-C3H1 PF10650.9 CBY30760.1 - 0.02 14.6 0.6 0.04 13.7 0.6 1.5 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.22 CBY30761.1 - 1.2e-42 145.3 0.0 1.8e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Ras family RabGAP-TBC PF00566.18 CBY30761.1 - 1.9e-34 119.2 1.6 3e-34 118.6 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Roc PF08477.13 CBY30761.1 - 1.5e-30 105.9 0.0 2.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY30761.1 - 1.5e-12 47.4 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY30761.1 - 0.0047 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY30761.1 - 0.035 13.5 0.5 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CBY30761.1 - 0.43 11.0 2.9 9.3 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DIRP PF06584.13 CBY30762.1 - 1.8e-37 127.7 0.2 4e-37 126.6 0.2 1.6 1 0 0 1 1 1 1 DIRP KxDL PF10241.9 CBY30762.1 - 0.0062 16.8 0.4 0.02 15.2 0.4 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2524 PF10732.9 CBY30762.1 - 0.022 15.0 0.5 0.39 11.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HNF-1_N PF04814.13 CBY30763.1 - 3.1 8.4 8.3 4.9 7.7 7.8 1.6 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus BIR PF00653.21 CBY30764.1 - 2.4e-31 108.2 3.0 3.9e-16 59.4 0.2 3.4 3 1 1 4 4 4 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 CBY30764.1 - 6.1e-09 35.6 14.0 6.1e-09 35.6 14.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY30764.1 - 0.7 9.8 15.3 0.7 9.8 13.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ribbon_3 PF13248.6 CBY30764.1 - 4.5 6.8 7.0 7.1 6.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain C8 PF08742.11 CBY30765.1 - 0.064 13.7 2.7 0.21 12.1 2.7 1.9 1 0 0 1 1 1 0 C8 domain EGF PF00008.27 CBY30766.1 - 9.3e-130 422.3 410.1 1.8e-07 31.3 8.9 26.6 26 0 0 26 26 26 21 EGF-like domain hEGF PF12661.7 CBY30766.1 - 3.6e-63 208.2 343.6 0.00013 22.4 4.7 27.4 27 0 0 27 27 27 21 Human growth factor-like EGF EGF_2 PF07974.13 CBY30766.1 - 2.1e-42 143.2 429.8 0.0063 16.9 10.6 26.9 26 0 0 26 26 26 22 EGF-like domain VWA_2 PF13519.6 CBY30766.1 - 3.1e-08 34.2 0.8 3.1e-08 34.2 0.8 2.9 2 1 0 2 2 2 1 von Willebrand factor type A domain cEGF PF12662.7 CBY30766.1 - 3.4e-08 33.3 295.9 0.0072 16.2 3.1 24.4 25 0 0 25 25 25 17 Complement Clr-like EGF-like CATSPERD PF15020.6 CBY30768.1 - 0.03 12.6 0.1 3.2 5.9 0.0 2.9 3 0 0 3 3 3 0 Cation channel sperm-associated protein subunit delta Glyco_hydro_9 PF00759.19 CBY30769.1 - 5.7e-122 408.1 5.9 7.5e-122 407.7 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF3747 PF12565.8 CBY30769.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DPBB_1 PF03330.18 CBY30769.1 - 0.067 13.5 1.9 0.14 12.4 0.2 2.5 3 0 0 3 3 3 0 Lytic transglycolase Aminotran_3 PF00202.21 CBY30770.1 - 7.9e-115 383.7 0.0 9.4e-115 383.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Oscp1 PF10188.9 CBY30771.1 - 1.2e-48 165.5 3.6 2.1e-48 164.8 3.6 1.4 1 0 0 1 1 1 1 Organic solute transport protein 1 SWIRM PF04433.17 CBY30771.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 SWIRM domain zf-ANAPC11 PF12861.7 CBY30771.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.22 CBY30773.1 - 9.8e-28 95.8 0.0 9.7e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY30773.1 - 2e-05 24.6 0.8 0.18 12.0 0.1 3.3 3 1 0 3 3 3 2 RNA recognition motif DUF4651 PF15513.6 CBY30773.1 - 0.0052 16.6 0.0 6 6.8 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4651) RRM_5 PF13893.6 CBY30773.1 - 0.0096 15.5 0.0 0.79 9.3 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBY30773.1 - 0.012 15.6 0.0 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif RRM_occluded PF16842.5 CBY30773.1 - 0.057 13.3 0.0 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Arf PF00025.21 CBY30775.1 - 3.2e-45 153.7 0.1 3.8e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY30775.1 - 1.2e-15 57.8 0.1 1.6e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY30775.1 - 2.2e-12 46.9 0.1 2.7e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBY30775.1 - 1.2e-11 44.3 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY30775.1 - 1.4e-10 40.9 1.4 3.3e-06 26.5 0.7 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY30775.1 - 3.5e-09 36.4 0.0 4.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY30775.1 - 2.1e-07 31.0 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY30775.1 - 0.0042 17.4 0.2 0.2 11.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBY30775.1 - 0.023 14.2 0.3 0.088 12.3 0.0 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Ank_2 PF12796.7 CBY30777.1 - 2.1e-19 69.9 0.1 1e-10 42.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY30777.1 - 2e-15 56.9 0.2 4.2e-07 30.4 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.28 CBY30777.1 - 2.4e-15 57.3 0.2 4e-13 50.1 0.2 2.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CBY30777.1 - 1.1e-12 48.6 5.2 1.1e-12 48.6 5.2 3.6 3 0 0 3 3 3 2 Pre-SET motif Ank_3 PF13606.6 CBY30777.1 - 4e-12 45.2 0.0 0.28 11.9 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBY30777.1 - 8.7e-11 41.9 0.6 0.04 14.2 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY30777.1 - 7.1e-06 26.2 0.1 1.3 9.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Transglut_i_TM PF14400.6 CBY30777.1 - 0.0074 16.4 0.7 0.6 10.2 0.0 2.4 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices zf-CCHC_3 PF13917.6 CBY30778.1 - 1.8e-06 27.8 0.0 1.8e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Zinc knuckle Rtf2 PF04641.12 CBY30778.1 - 0.001 18.5 4.3 0.001 18.5 4.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-CCHC PF00098.23 CBY30778.1 - 0.0015 18.5 4.0 0.0024 17.9 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Transformer PF06495.11 CBY30778.1 - 0.048 13.8 14.9 0.05 13.7 14.9 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF2229 PF09989.9 CBY30778.1 - 0.72 9.5 3.9 0.79 9.3 3.8 1.2 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2207 PF09972.9 CBY30778.1 - 2.3 6.9 4.8 2.8 6.6 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S49_N PF08496.10 CBY30778.1 - 3.5 7.7 10.7 5 7.2 10.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 CBY30778.1 - 5.8 5.7 14.3 7.1 5.4 14.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4228 PF14009.6 CBY30778.1 - 8.2 6.8 11.2 12 6.2 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) An_peroxidase PF03098.15 CBY30779.1 - 8.1e-132 440.5 0.0 1.9e-96 323.8 0.0 2.2 2 0 0 2 2 2 2 Animal haem peroxidase I-set PF07679.16 CBY30779.1 - 1.5e-38 130.8 0.0 2.7e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY30779.1 - 1.1e-29 102.9 0.1 2.1e-09 37.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY30779.1 - 1.8e-23 82.6 0.1 1.3e-07 31.9 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CBY30779.1 - 2.7e-22 78.7 0.2 5.1e-07 29.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain LRR_8 PF13855.6 CBY30779.1 - 1.2e-14 53.7 2.8 9.4e-13 47.7 1.5 2.6 2 0 0 2 2 2 1 Leucine rich repeat V-set PF07686.17 CBY30779.1 - 7.8e-07 29.3 0.5 0.78 9.9 0.0 4.8 3 2 0 4 4 4 2 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY30779.1 - 1.7e-05 24.3 0.0 2.5 7.7 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain Ig_4 PF16680.5 CBY30779.1 - 4.7e-05 23.6 0.0 3 8.2 0.0 4.0 3 1 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain LRR_4 PF12799.7 CBY30779.1 - 0.00015 22.0 7.7 0.0024 18.2 0.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY30779.1 - 0.00023 21.1 0.4 0.00074 19.5 0.4 1.8 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Herpes_gE PF02480.16 CBY30779.1 - 0.00029 19.7 0.1 0.56 8.9 0.0 2.8 3 0 0 3 3 3 2 Alphaherpesvirus glycoprotein E C1-set PF07654.15 CBY30779.1 - 0.00085 19.7 0.0 0.2 12.0 0.0 3.0 2 1 0 2 2 2 1 Immunoglobulin C1-set domain LRR_1 PF00560.33 CBY30779.1 - 0.0048 17.2 2.3 2.2 9.1 0.0 4.8 3 1 1 4 4 4 1 Leucine Rich Repeat C2-set_2 PF08205.12 CBY30779.1 - 0.009 16.1 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain LRR_9 PF14580.6 CBY30779.1 - 0.022 14.2 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRRNT PF01462.18 CBY30779.1 - 2.9 7.6 7.8 0.5 10.1 3.3 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain WD40 PF00400.32 CBY30780.1 - 6.9e-61 200.8 77.7 3.4e-05 24.5 0.0 27.0 29 0 0 29 29 28 12 WD domain, G-beta repeat HELP PF03451.14 CBY30780.1 - 9.4e-43 143.9 0.1 1.3e-15 57.0 0.0 3.4 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 CBY30780.1 - 1.7e-36 124.4 8.2 4.6e-05 23.6 0.0 14.5 10 3 5 16 16 16 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY30780.1 - 3.9e-14 53.0 2.7 1.5e-05 24.9 0.1 6.7 6 2 0 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY30780.1 - 2.1e-09 37.2 8.9 0.00015 21.2 0.4 7.5 5 4 2 7 7 7 2 WD40-like domain Frtz PF11768.8 CBY30780.1 - 2.8e-09 35.9 0.1 0.12 10.7 0.0 4.1 3 1 1 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CBY30780.1 - 9.6e-09 34.2 0.0 4e-05 22.3 0.0 4.4 5 0 0 5 5 5 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CBY30780.1 - 8.6e-08 31.3 0.0 0.027 13.2 0.0 3.9 3 0 0 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.6 CBY30780.1 - 3e-06 27.2 0.5 4.6 7.3 0.0 7.6 9 1 1 10 10 8 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBY30780.1 - 9.5e-06 24.5 0.0 0.15 10.7 0.0 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 MMS1_N PF10433.9 CBY30780.1 - 0.00022 20.0 0.0 0.057 12.0 0.0 3.5 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Formyl_trans_C PF02911.18 CBY30780.1 - 0.0018 18.5 0.8 3.8 7.8 0.1 4.1 3 1 1 4 4 4 1 Formyl transferase, C-terminal domain Ge1_WD40 PF16529.5 CBY30780.1 - 0.004 16.2 0.8 2.1 7.2 0.0 4.8 4 2 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBY30780.1 - 0.014 15.3 0.1 23 5.1 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 CBY30780.1 - 0.054 12.8 0.0 2.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FtsK_SpoIIIE_N PF12538.8 CBY30780.1 - 0.11 12.8 0.3 2.6 8.3 0.0 3.1 3 0 0 3 3 3 0 DNA transporter SNAPc_SNAP43 PF09808.9 CBY30781.1 - 4.7e-20 72.3 0.1 4.7e-20 72.3 0.1 2.5 2 1 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 AMPKBI PF04739.15 CBY30781.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain SPC22 PF04573.12 CBY30782.1 - 1.2e-49 168.1 0.0 1.4e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit WAC_Acf1_DNA_bd PF10537.9 CBY30783.1 - 5.7e-11 42.8 0.3 2e-10 41.1 0.3 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CBY30783.1 - 7.4e-08 32.8 1.9 2.3e-06 28.0 0.8 3.4 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF1803 PF08820.10 CBY30783.1 - 0.0085 16.1 0.6 8.2 6.5 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1803) RAMP PF04901.13 CBY30783.1 - 0.0099 15.9 0.2 0.049 13.6 0.1 2.2 2 0 0 2 2 2 1 Receptor activity modifying family tRNA_lig_kinase PF08303.11 CBY30783.1 - 0.03 14.4 1.5 0.07 13.2 0.3 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain Glyco_hydro_31 PF01055.26 CBY30784.1 - 4.7e-140 467.7 4.5 6.3e-140 467.2 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY30784.1 - 2.4e-16 59.9 0.2 2.4e-16 59.9 0.2 1.8 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CBY30784.1 - 0.027 14.8 0.1 0.061 13.6 0.1 1.6 1 0 0 1 1 1 0 Galactose mutarotase-like Nucleo_P87 PF07267.11 CBY30785.1 - 9.8 4.9 11.0 0.23 10.3 3.3 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 mRNA_cap_enzyme PF01331.19 CBY30786.1 - 1.2e-44 152.5 0.0 2.1e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CBY30786.1 - 8.9e-20 71.3 0.1 2.3e-19 70.0 0.1 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CBY30786.1 - 8.2e-06 25.6 0.0 0.027 14.1 0.0 2.6 1 1 1 2 2 2 2 ATP dependent DNA ligase domain CCSAP PF15748.5 CBY30787.1 - 0.26 11.4 35.7 0.12 12.5 19.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 CBY30787.1 - 0.41 8.9 33.5 0.67 8.2 4.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Hid1 PF12722.7 CBY30787.1 - 3.1 5.8 24.3 2.7 6.0 12.5 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein BAF1_ABF1 PF04684.13 CBY30787.1 - 4.9 6.1 32.8 4.6 6.2 18.1 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.25 CBY30788.1 - 4.1e-62 209.9 0.0 5.5e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30788.1 - 1.2e-35 123.0 0.0 2.7e-34 118.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBY30788.1 - 0.0054 15.8 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CBY30788.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SF1-HH PF16275.5 CBY30789.1 - 0.039 14.3 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain bZIP_2 PF07716.15 CBY30791.1 - 2.6e-06 27.4 11.0 2.6e-06 27.4 11.0 2.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY30791.1 - 0.0021 18.1 15.3 0.0034 17.5 15.3 1.3 1 1 0 1 1 1 1 bZIP transcription factor DUF773 PF05600.12 CBY30791.1 - 0.17 10.5 8.5 0.21 10.3 8.5 1.0 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF21 PF01595.20 CBY30792.1 - 1.3e-29 103.2 0.1 2.4e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBY30792.1 - 2e-09 37.7 2.4 1.5e-05 25.4 0.1 2.9 3 0 0 3 3 3 2 CBS domain cNMP_binding PF00027.29 CBY30792.1 - 0.026 14.6 0.0 0.082 13.0 0.0 1.8 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBY30793.1 - 4e-47 160.8 0.0 4.7e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30793.1 - 6.4e-14 51.9 0.0 8.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY30793.1 - 7.7e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY30793.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY30793.1 - 0.0026 17.7 0.1 0.0047 16.9 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY30793.1 - 0.0048 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY30793.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family S_locus_glycop PF00954.20 CBY30793.1 - 0.016 15.7 0.0 0.033 14.7 0.0 1.6 1 1 0 1 1 1 0 S-locus glycoprotein domain Haspin_kinase PF12330.8 CBY30793.1 - 0.14 11.0 0.1 0.37 9.7 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Sulfatase PF00884.23 CBY30794.1 - 4.1e-58 197.2 0.0 4.9e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY30794.1 - 0.00097 18.8 0.0 0.012 15.2 0.0 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY30794.1 - 0.094 12.6 0.1 0.66 9.9 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function Pellino PF04710.14 CBY30794.1 - 0.14 10.8 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 Pellino DUF1501 PF07394.12 CBY30794.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UNC80 PF15778.5 CBY30795.1 - 3.2e-20 72.5 0.4 1.6e-17 63.7 0.4 2.7 1 1 0 1 1 1 1 Cation channel complex component UNC80 DUF719 PF05334.13 CBY30795.1 - 0.18 12.0 5.5 0.069 13.3 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) Nop53 PF07767.11 CBY30796.1 - 1.8 7.8 8.0 2.4 7.4 8.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Peptidase_S8 PF00082.22 CBY30797.1 - 2.3e-25 89.5 4.9 3.1e-25 89.0 4.9 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY30797.1 - 2.1e-12 46.9 0.1 5.5e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain ERM PF00769.19 CBY30798.1 - 0.011 15.6 27.5 0.015 15.2 27.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mucin PF01456.17 CBY30798.1 - 0.044 13.8 41.6 0.085 12.9 41.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF572 PF04502.13 CBY30798.1 - 0.17 11.5 18.8 0.3 10.7 18.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.13 CBY30798.1 - 1.3 7.3 14.7 1.7 6.9 14.7 1.0 1 0 0 1 1 1 0 Menin Sporozoite_P67 PF05642.11 CBY30798.1 - 1.7 6.6 17.6 3 5.8 17.6 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen UPAR_LY6 PF00021.21 CBY30798.1 - 3.9 8.2 13.2 0.12 13.1 5.9 2.1 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Peptidase_S64 PF08192.11 CBY30798.1 - 9.1 4.6 11.9 12 4.3 11.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF966 PF06136.13 CBY30798.1 - 9.2 5.9 17.8 13 5.4 17.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TAFII28 PF04719.14 CBY30799.1 - 3.8e-32 110.2 0.2 7.6e-32 109.3 0.2 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region RasGAP_C PF03836.15 CBY30799.1 - 0.0027 17.8 0.3 0.0045 17.1 0.3 1.5 1 0 0 1 1 1 1 RasGAP C-terminus RRM_1 PF00076.22 CBY30800.1 - 6.5e-25 86.7 1.5 2.9e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY30800.1 - 1.4e-09 37.7 0.1 0.0012 18.4 0.5 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY30800.1 - 1.6e-07 31.1 0.2 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY30800.1 - 0.031 14.4 0.0 5.8 7.1 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY30800.1 - 0.19 11.8 0.2 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF2605 PF10792.9 CBY30800.1 - 0.37 10.7 6.3 7.8 6.5 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2605) GET2 PF08690.10 CBY30800.1 - 0.64 9.6 13.5 0.97 9.0 13.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 AAA PF00004.29 CBY30801.1 - 2.8e-35 121.6 0.0 6.9e-35 120.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY30801.1 - 1.2e-07 32.3 0.0 0.00014 22.3 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CBY30801.1 - 2.2e-06 27.7 0.0 5.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBY30801.1 - 2.5e-06 27.7 0.0 5.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CBY30801.1 - 3.2e-05 23.2 0.0 0.00012 21.4 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBY30801.1 - 0.00016 22.0 0.5 0.0058 16.9 0.5 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBY30801.1 - 0.00044 20.0 0.0 0.00094 19.0 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBY30801.1 - 0.00072 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Vps4_C PF09336.10 CBY30801.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 CBY30801.1 - 0.0019 18.2 0.0 0.015 15.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain MCM PF00493.23 CBY30801.1 - 0.002 17.3 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain Kinesin PF00225.23 CBY30801.1 - 0.0056 15.6 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain IstB_IS21 PF01695.17 CBY30801.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 CBY30801.1 - 0.009 15.7 1.6 0.01 15.6 0.2 1.9 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CBY30801.1 - 0.012 15.5 1.9 0.64 9.9 0.1 3.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CBY30801.1 - 0.017 14.7 0.0 0.053 13.0 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 CBY30801.1 - 0.017 15.5 0.7 0.14 12.5 0.1 2.3 2 1 1 3 3 3 0 AAA domain TsaE PF02367.17 CBY30801.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CBY30801.1 - 0.038 14.5 0.1 0.43 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY30801.1 - 0.048 13.8 0.0 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBY30801.1 - 0.054 13.2 0.0 0.099 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY30801.1 - 0.055 13.7 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 CBY30801.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CBY30801.1 - 0.067 12.5 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 KaiC ABC_tran PF00005.27 CBY30801.1 - 0.087 13.3 0.1 0.37 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 CBY30801.1 - 0.089 12.2 0.1 0.3 10.4 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CBY30801.1 - 0.094 12.3 0.1 0.5 9.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBY30801.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 CBY30801.1 - 0.097 12.4 0.0 0.097 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBY30801.1 - 0.11 11.8 0.0 8.8 5.4 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 CBY30801.1 - 0.13 12.7 0.0 0.34 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CBY30801.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nucleo_P87 PF07267.11 CBY30801.1 - 0.2 10.5 2.4 0.32 9.8 2.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 CBY30802.1 - 1.5e-71 240.9 0.0 1.7e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30802.1 - 1.1e-36 126.5 0.1 3.8e-36 124.7 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY30802.1 - 0.015 14.6 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like STAR_dimer PF16544.5 CBY30806.1 - 4.8e-22 77.3 0.4 1.1e-21 76.1 0.4 1.6 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein KH_1 PF00013.29 CBY30806.1 - 4.8e-07 29.5 0.1 1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 KH domain STAR_dimer PF16544.5 CBY30807.1 - 4.6e-10 38.9 0.2 7.2e-10 38.3 0.2 1.2 1 0 0 1 1 1 1 Homodimerisation region of STAR domain protein EGF PF00008.27 CBY30808.1 - 6.3e-09 36.0 69.6 0.00011 22.5 3.0 6.3 5 1 1 6 6 6 4 EGF-like domain EGF_2 PF07974.13 CBY30808.1 - 8.2e-06 26.1 85.9 0.014 15.8 10.2 6.5 7 0 0 7 7 7 5 EGF-like domain Mucin PF01456.17 CBY30808.1 - 0.0076 16.2 26.2 0.0076 16.2 26.2 2.2 1 1 1 2 2 2 1 Mucin-like glycoprotein DUF2325 PF10087.9 CBY30808.1 - 0.018 15.1 0.1 6.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) hEGF PF12661.7 CBY30808.1 - 0.14 12.8 0.6 0.14 12.8 0.6 7.3 5 2 1 6 6 6 0 Human growth factor-like EGF Laminin_EGF PF00053.24 CBY30808.1 - 0.79 9.9 62.7 1.5 9.1 5.0 5.5 1 1 4 5 5 5 0 Laminin EGF domain DUF936 PF06075.12 CBY30808.1 - 8.1 5.2 10.6 12 4.7 10.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Kinesin PF00225.23 CBY30809.1 - 4.3e-112 374.3 0.5 4.3e-112 374.3 0.5 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY30809.1 - 1.5e-27 96.4 0.1 1.5e-27 96.4 0.1 3.0 3 0 0 3 3 3 1 Microtubule binding ApoLp-III PF07464.11 CBY30809.1 - 0.00023 21.3 8.9 0.00023 21.3 8.9 5.4 1 1 4 5 5 5 3 Apolipophorin-III precursor (apoLp-III) Filament PF00038.21 CBY30809.1 - 0.86 9.1 59.5 0.18 11.3 27.9 3.3 1 1 2 3 3 3 0 Intermediate filament protein CK2S PF15011.6 CBY30809.1 - 3.2 7.6 28.0 0.7 9.8 0.4 5.3 1 1 3 5 5 5 0 Casein Kinase 2 substrate HU-CCDC81_bac_2 PF18175.1 CBY30809.1 - 5 7.1 6.5 9.8 6.1 0.2 4.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Baculo_PEP_C PF04513.12 CBY30809.1 - 7.5 6.6 23.2 1.7 8.6 1.3 4.9 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin_2 PF09361.10 CBY30809.1 - 8 6.8 26.9 0.68 10.2 7.7 4.9 3 1 1 4 4 4 0 Phasin protein PLAT PF01477.23 CBY30810.1 - 3.6e-06 27.5 0.5 0.00024 21.6 0.0 2.9 3 0 0 3 3 3 1 PLAT/LH2 domain Transglut_N PF00868.20 CBY30810.1 - 0.0012 19.2 0.1 0.25 11.7 0.0 3.5 2 1 1 3 3 3 1 Transglutaminase family Collagen PF01391.18 CBY30811.1 - 1.4e-51 172.0 221.2 1.7e-10 40.5 26.4 7.4 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) PBD PF00786.28 CBY30812.1 - 0.013 15.8 0.1 0.041 14.3 0.1 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain ELFV_dehydrog PF00208.21 CBY30813.1 - 5.8e-84 281.6 1.1 7.5e-84 281.2 1.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBY30813.1 - 1.4e-53 180.3 0.0 3.6e-53 178.9 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 CBY30813.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBY30813.1 - 0.0018 18.7 0.0 0.0035 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding SHNi-TPR PF10516.9 CBY30814.1 - 0.0014 18.0 0.3 2.4 7.7 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR SHOCT PF09851.9 CBY30814.1 - 0.0042 16.8 2.0 2.2 8.1 0.2 2.4 2 0 0 2 2 2 2 Short C-terminal domain ArgJ PF01960.18 CBY30814.1 - 0.0049 15.6 0.0 0.6 8.8 0.0 2.1 2 0 0 2 2 2 2 ArgJ family Pam17 PF08566.10 CBY30814.1 - 0.0069 16.2 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial import protein Pam17 DUF4532 PF15046.6 CBY30814.1 - 0.095 11.9 0.3 9 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4532) IL1_propep PF02394.16 CBY30814.1 - 0.21 12.5 0.8 32 5.5 0.1 2.7 2 0 0 2 2 2 0 Interleukin-1 propeptide L_biotic_typeA PF04604.13 CBY30814.1 - 0.31 10.9 4.8 9 6.2 0.4 2.6 2 0 0 2 2 2 0 Type-A lantibiotic CHORD PF04968.12 CBY30814.1 - 0.49 11.1 21.4 8 7.3 0.6 4.8 2 2 2 4 4 4 0 CHORD zf-C2H2 PF00096.26 CBY30815.1 - 1.3e-06 28.5 6.1 0.00068 19.9 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY30815.1 - 0.00015 22.3 6.2 0.0028 18.4 1.3 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CBY30815.1 - 0.0016 18.7 0.2 79 3.7 0.1 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY30815.1 - 0.0043 17.4 1.5 0.023 15.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY30815.1 - 0.01 15.8 3.1 0.034 14.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY30815.1 - 0.011 16.1 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY30815.1 - 0.029 14.7 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon CpXC PF14353.6 CBY30815.1 - 0.12 12.4 0.1 9.5 6.3 0.0 2.7 1 1 1 2 2 2 0 CpXC protein zf-H2C2_2 PF13465.6 CBY30815.1 - 0.97 10.0 9.9 0.78 10.3 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double domain TMEM214 PF10151.9 CBY30815.1 - 5.1 5.4 9.2 7.6 4.9 9.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MIP PF00230.20 CBY30816.1 - 7.7e-08 32.3 0.6 1e-07 32.0 0.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein CHB_HEX_C PF03174.13 CBY30817.1 - 2.3e-07 30.7 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Glyco_hydro_20 PF00728.22 CBY30818.1 - 1.1e-62 212.5 0.4 1.7e-62 211.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Kinesin PF00225.23 CBY30819.1 - 1.5e-103 346.2 3.7 1.5e-103 346.2 3.7 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY30819.1 - 6.6e-46 155.9 0.2 1.7e-45 154.6 0.2 1.7 1 0 0 1 1 1 1 Microtubule binding MAD PF05557.13 CBY30819.1 - 0.0014 17.1 26.9 0.0028 16.1 26.9 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein Sec34 PF04136.15 CBY30819.1 - 0.068 13.1 19.4 0.067 13.1 2.6 3.2 1 1 2 3 3 3 0 Sec34-like family APG6_N PF17675.1 CBY30819.1 - 0.12 12.9 36.9 0.12 12.9 16.9 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBY30819.1 - 0.12 11.6 24.5 0.72 9.1 11.8 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBY30819.1 - 0.19 10.5 33.8 0.076 11.9 22.1 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CBY30819.1 - 0.22 10.8 34.8 0.13 11.6 21.6 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 CBY30819.1 - 0.26 11.3 14.4 0.91 9.5 8.5 3.1 2 0 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 CBY30819.1 - 0.76 9.8 33.8 0.054 13.6 27.3 2.5 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY30819.1 - 0.78 9.8 24.9 1 9.4 5.8 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CBY30819.1 - 1.3 6.9 12.0 2.3 6.1 12.0 1.4 1 0 0 1 1 1 0 Prominin HIP1_clath_bdg PF16515.5 CBY30819.1 - 1.6 9.4 30.9 0.67 10.6 14.0 3.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 CBY30819.1 - 2 8.9 23.3 19 5.8 17.0 3.4 2 1 1 3 3 2 0 Protein of unknown function DUF16 XhlA PF10779.9 CBY30819.1 - 2.1 8.6 26.3 2.2 8.6 2.7 4.6 2 1 2 4 4 4 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 CBY30819.1 - 3.6 7.6 42.0 0.19 11.7 17.0 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 CBY30819.1 - 4.8 6.0 37.5 24 3.6 33.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) DUF2968 PF11180.8 CBY30819.1 - 5.2 6.7 22.0 5.9 6.5 7.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) UPF0449 PF15136.6 CBY30819.1 - 9.8 6.7 22.2 1.6 9.3 7.7 2.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 ERK-JNK_inhib PF15002.6 CBY30820.1 - 3.3e-57 193.3 9.6 3.8e-57 193.1 9.6 1.0 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor HMG_box_5 PF14887.6 CBY30820.1 - 0.034 14.1 0.3 0.034 14.1 0.3 2.1 3 0 0 3 3 3 0 HMG (high mobility group) box 5 Raptor_N PF14538.6 CBY30820.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF3527 PF12043.8 CBY30820.1 - 0.09 12.3 0.2 0.09 12.3 0.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3527) TrwC PF08751.11 CBY30820.1 - 0.55 9.7 4.0 0.7 9.3 1.6 1.9 1 1 1 2 2 2 0 TrwC relaxase NERD PF08378.11 CBY30821.1 - 0.0004 20.8 0.0 0.00073 20.0 0.0 1.4 1 0 0 1 1 1 1 Nuclease-related domain Glyco_transf_90 PF05686.12 CBY30822.1 - 9.7e-72 242.1 5.4 1.3e-71 241.6 5.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 CBY30822.1 - 0.041 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Phospholip_A2_1 PF00068.19 CBY30824.1 - 4.1e-11 43.3 10.6 4.1e-11 43.3 10.6 2.2 2 0 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.12 CBY30824.1 - 0.51 10.9 6.0 0.57 10.8 4.2 1.9 2 0 0 2 2 2 0 Poxvirus A21 Protein P5CR_dimer PF14748.6 CBY30825.1 - 2.3e-39 133.8 1.1 5.1e-39 132.7 1.1 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBY30825.1 - 2.5e-14 53.6 0.1 5.7e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBY30825.1 - 0.00035 20.8 0.3 0.00062 20.0 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RcsD_ABL PF16359.5 CBY30825.1 - 0.041 14.0 0.0 3.6 7.8 0.0 2.2 2 0 0 2 2 2 0 RcsD-ABL domain Ribosomal_S11 PF00411.19 CBY30825.1 - 0.053 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 C6_DPF PF10170.9 CBY30825.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 Cysteine-rich domain zf-DBF PF07535.12 CBY30826.1 - 0.0038 17.3 0.9 0.0038 17.3 0.9 2.0 2 0 0 2 2 2 1 DBF zinc finger TetR_C_2 PF08361.11 CBY30826.1 - 0.023 14.8 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region CYLD_phos_site PF16607.5 CBY30827.1 - 0.73 9.7 9.3 0.057 13.3 3.8 1.9 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured PLAC8 PF04749.17 CBY30829.1 - 8e-14 52.4 10.9 9.6e-14 52.2 10.9 1.1 1 0 0 1 1 1 1 PLAC8 family C6_DPF PF10170.9 CBY30829.1 - 0.66 10.4 9.2 2.5 8.5 0.4 2.1 1 1 1 2 2 2 0 Cysteine-rich domain EGF_CA PF07645.15 CBY30832.1 - 5.3e-202 653.9 552.1 1.1e-10 41.5 10.5 34.3 28 4 6 34 34 34 31 Calcium-binding EGF domain EGF_3 PF12947.7 CBY30832.1 - 5.3e-183 592.9 521.7 5.4e-10 39.3 13.1 34.3 29 4 5 34 34 34 32 EGF domain cEGF PF12662.7 CBY30832.1 - 2.7e-117 382.1 339.5 1e-07 31.7 3.8 33.0 31 1 1 32 32 32 29 Complement Clr-like EGF-like EGF PF00008.27 CBY30832.1 - 1.2e-83 274.9 427.0 2.4e-06 27.7 7.7 34.1 29 4 4 33 33 33 28 EGF-like domain hEGF PF12661.7 CBY30832.1 - 9.1e-53 175.2 360.8 0.00016 22.1 3.1 36.1 36 1 1 37 37 37 27 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY30832.1 - 1.5e-52 175.4 422.0 1.8e-06 27.9 8.5 33.8 28 5 6 34 34 34 26 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY30832.1 - 8.3e-22 77.2 422.7 0.026 14.8 10.4 32.4 14 9 16 30 30 30 18 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY30832.1 - 3.1e-12 46.6 431.6 0.0033 17.7 7.8 32.1 28 4 3 31 31 31 19 Pvs28 EGF domain Utp14 PF04615.13 CBY30832.1 - 3.5 6.1 18.8 5 5.6 18.8 1.1 1 0 0 1 1 1 0 Utp14 protein EGF_CA PF07645.15 CBY30833.1 - 2.1e-228 738.4 555.8 5.8e-12 45.6 7.5 35.1 30 4 4 34 34 34 31 Calcium-binding EGF domain EGF_3 PF12947.7 CBY30833.1 - 6.6e-156 506.2 506.2 4e-09 36.5 6.8 33.6 28 4 3 32 32 32 30 EGF domain cEGF PF12662.7 CBY30833.1 - 2.2e-119 388.7 362.9 5.9e-06 26.1 0.4 35.3 34 1 0 34 34 34 31 Complement Clr-like EGF-like EGF PF00008.27 CBY30833.1 - 7.8e-59 195.5 412.9 0.00011 22.4 6.8 34.9 32 3 0 32 32 32 26 EGF-like domain EGF_MSP1_1 PF12946.7 CBY30833.1 - 6.5e-47 157.3 408.7 2e-05 24.5 6.5 32.3 31 2 1 32 32 32 22 MSP1 EGF domain 1 hEGF PF12661.7 CBY30833.1 - 2.5e-45 151.6 370.4 0.0084 16.7 3.1 37.1 36 2 0 36 36 36 27 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY30833.1 - 9.1e-33 112.3 432.9 0.007 16.6 6.8 32.7 20 5 12 32 32 32 26 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY30833.1 - 9.6e-25 86.6 411.4 0.0002 21.6 12.3 31.0 28 3 2 30 30 30 23 Pvs28 EGF domain TMEM52 PF14979.6 CBY30836.1 - 0.036 14.0 6.1 0.12 12.3 6.1 1.8 1 1 0 1 1 1 0 Transmembrane 52 ABC2_membrane_3 PF12698.7 CBY30836.1 - 0.34 10.0 0.4 0.41 9.7 0.1 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein TMEM174 PF15029.6 CBY30836.1 - 0.44 10.2 4.5 7.4 6.2 0.9 2.2 1 1 1 2 2 2 0 Transmembrane protein 174 RVT_1 PF00078.27 CBY30837.1 - 2.1e-27 96.1 0.0 5e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAS_C PF12026.8 CBY30837.1 - 0.068 13.2 0.3 0.4 10.8 0.4 2.2 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain DHO_dh PF01180.21 CBY30837.1 - 0.11 11.7 2.6 0.24 10.6 2.6 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase GDPD PF03009.17 CBY30840.1 - 2.7e-05 24.0 0.0 3.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4996 PF16387.5 CBY30840.1 - 0.028 14.9 0.0 0.052 14.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function SPT6_acidic PF14632.6 CBY30840.1 - 0.11 13.1 9.6 0.15 12.7 9.6 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 GDPD_2 PF13653.6 CBY30840.1 - 0.15 12.6 0.0 0.4 11.2 0.0 1.8 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Sulfotransfer_1 PF00685.27 CBY30841.1 - 1.8e-18 67.0 0.1 1.8e-18 67.0 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30841.1 - 6.6e-14 52.8 0.0 9.1e-05 22.9 0.0 3.4 2 1 1 3 3 3 3 Sulfotransferase family DUF2183 PF09949.9 CBY30841.1 - 0.76 10.2 3.0 12 6.3 0.0 3.3 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2183) WD40 PF00400.32 CBY30842.1 - 5.2e-10 39.8 8.1 0.00027 21.7 0.3 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY30842.1 - 3.1e-07 30.6 0.3 0.31 11.4 0.0 4.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Gly-zipper_YMGG PF13441.6 CBY30843.1 - 0.0087 15.8 38.7 0.011 15.4 30.5 2.4 1 1 1 2 2 2 2 YMGG-like Gly-zipper TraT PF05818.12 CBY30843.1 - 0.013 15.2 6.7 0.017 14.8 6.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.6 CBY30843.1 - 0.28 11.0 40.8 3.8 7.4 31.9 2.7 1 1 1 2 2 2 0 Glycine-zipper domain DUF1269 PF06897.12 CBY30843.1 - 0.62 10.4 17.0 0.38 11.1 14.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 CBY30843.1 - 4.3 7.4 41.9 22 5.2 38.2 2.8 1 1 1 2 2 2 0 Glycine zipper Keratin_2_head PF16208.5 CBY30843.1 - 4.8 7.3 16.7 6.4 6.9 16.7 1.1 1 0 0 1 1 1 0 Keratin type II head DUF533 PF04391.12 CBY30843.1 - 5.4 6.5 6.6 7.8 6.0 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DUF726 PF05277.12 CBY30843.1 - 8.7 5.2 10.7 11 4.9 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) CBM_14 PF01607.24 CBY30844.1 - 5.7e-12 45.6 7.5 1.8e-11 44.0 5.6 2.1 1 1 1 2 2 2 1 Chitin binding Peritrophin-A domain Frag1 PF10277.9 CBY30845.1 - 4e-27 95.2 10.0 4.9e-27 94.9 10.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tup_N PF08581.10 CBY30846.1 - 0.0043 17.3 2.5 0.0043 17.3 2.5 2.1 1 1 1 2 2 2 1 Tup N-terminal DUF1640 PF07798.11 CBY30846.1 - 5.8 6.9 15.2 8.1 6.5 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Choline_kinase PF01633.20 CBY30847.1 - 1.9e-14 53.8 0.1 2.9e-14 53.2 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY30847.1 - 1.1e-12 48.5 0.0 1.4e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY30847.1 - 4.2e-05 23.0 0.1 6.3e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 CBY30847.1 - 0.11 11.7 0.3 0.73 9.0 0.3 2.0 1 1 0 1 1 1 0 Fructosamine kinase zf-H2C2_2 PF13465.6 CBY30848.1 - 5.9e-19 67.6 21.7 2.2e-08 34.2 1.6 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY30848.1 - 2.8e-12 46.4 28.1 5.5e-06 26.5 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY30848.1 - 6.2e-09 35.9 25.3 0.0011 19.6 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY30848.1 - 1.9e-06 27.7 19.7 0.0028 17.6 2.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY30848.1 - 0.0012 18.5 0.4 0.0012 18.5 0.4 4.4 3 1 0 3 3 2 1 C2H2-type zinc-finger domain C1_4 PF07975.12 CBY30848.1 - 0.013 15.7 5.2 0.013 15.7 5.2 3.1 1 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CBY30848.1 - 0.016 15.5 9.0 3.6 8.0 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 CBY30848.1 - 0.049 13.6 7.5 0.081 12.9 7.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-met PF12874.7 CBY30848.1 - 0.088 13.2 0.3 0.088 13.2 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY30848.1 - 0.14 11.9 0.1 0.14 11.9 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zf_RING PF16744.5 CBY30848.1 - 0.3 11.2 15.5 0.24 11.5 0.7 3.2 1 1 0 2 2 2 0 KIAA1045 RING finger IBR PF01485.21 CBY30848.1 - 0.36 11.1 8.7 0.098 12.9 4.4 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2HC_2 PF13913.6 CBY30848.1 - 0.58 10.1 11.3 1.5 8.8 0.8 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 CBY30848.1 - 0.61 10.0 13.7 0.56 10.2 0.7 3.4 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 CBY30848.1 - 0.92 9.8 8.8 3 8.2 1.9 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 CBY30848.1 - 2.4 8.7 12.7 20 5.7 6.3 3.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_9 PF14369.6 CBY30848.1 - 3.3 8.1 8.4 0.36 11.1 2.5 2.6 2 1 0 2 2 1 0 zinc-ribbon GAGA PF09237.11 CBY30848.1 - 3.5 7.5 6.3 12 5.8 3.3 2.6 1 1 1 2 2 2 0 GAGA factor PfkB PF00294.24 CBY30849.1 - 7.5e-11 41.9 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cortex-I_coil PF09304.10 CBY30849.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Defb50 PF17546.2 CBY30849.1 - 0.078 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Beta defensin 50 Collagen PF01391.18 CBY30850.1 - 7.8e-14 51.2 88.4 6.3e-05 22.6 41.3 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Acyl-CoA_dh_1 PF00441.24 CBY30852.1 - 1.3e-38 132.6 0.2 2e-38 132.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY30852.1 - 3e-25 89.1 0.0 6.1e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY30852.1 - 7.6e-25 86.9 0.1 1.8e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY30852.1 - 5.3e-15 55.9 0.0 8.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY30852.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1175 PF06672.11 CBY30852.1 - 0.078 12.7 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) Neur_chan_LBD PF02931.23 CBY30853.1 - 2.4e-30 105.6 6.6 3.3e-30 105.2 6.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY30853.1 - 0.029 14.4 6.3 0.047 13.8 6.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_Cse60 PF10957.8 CBY30853.1 - 0.03 14.4 0.1 7.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Sporulation protein Cse60 CLZ PF16526.5 CBY30854.1 - 0.0046 17.3 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4200 PF13863.6 CBY30854.1 - 0.018 15.4 0.5 0.018 15.4 0.5 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ATF7IP_BD PF16788.5 CBY30854.1 - 0.068 13.3 7.9 0.088 12.9 7.9 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF4446 PF14584.6 CBY30854.1 - 0.094 12.7 0.1 0.18 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) HrpB7 PF09486.10 CBY30854.1 - 0.28 11.6 1.6 0.42 11.0 0.4 1.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TPPK_C PF12555.8 CBY30854.1 - 0.29 11.2 2.5 0.51 10.4 2.5 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Lin-8 PF03353.15 CBY30854.1 - 0.34 10.4 6.3 0.45 10.0 6.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SKA1 PF07160.12 CBY30854.1 - 0.49 10.2 7.7 0.68 9.7 7.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4690 PF15756.5 CBY30854.1 - 0.99 10.0 3.0 0.61 10.7 0.5 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Not3 PF04065.15 CBY30854.1 - 1.5 8.2 6.7 0.14 11.5 0.4 1.9 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component SKG6 PF08693.10 CBY30854.1 - 2.5 7.6 6.2 6.5 6.3 6.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Frag1 PF10277.9 CBY30855.1 - 6.8e-21 74.8 16.8 8.2e-21 74.5 16.8 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family HOK_GEF PF01848.16 CBY30855.1 - 0.05 13.0 0.3 0.05 13.0 0.3 2.4 2 0 0 2 2 2 0 Hok/gef family MSC PF09402.10 CBY30855.1 - 0.14 11.6 2.4 0.15 11.4 0.6 1.7 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF423 PF04241.15 CBY30855.1 - 1.7 8.9 6.5 0.6 10.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF4131 PF13567.6 CBY30855.1 - 3.9 7.1 9.8 2.3 7.9 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Spermine_synth PF01564.17 CBY30857.1 - 6.3e-25 87.7 0.0 8.1e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CBY30857.1 - 7e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_12 PF08242.12 CBY30857.1 - 0.0012 19.5 0.0 0.0024 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Trypsin PF00089.26 CBY30859.1 - 1.8e-57 194.7 0.6 2.2e-57 194.4 0.6 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY30859.1 - 6.8e-06 27.1 0.0 1.2e-05 26.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY30859.1 - 0.0038 17.6 0.1 0.0096 16.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Aldo_ket_red PF00248.21 CBY30860.1 - 2.9e-05 23.4 0.3 6.7e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family UNC-93 PF05978.16 CBY30861.1 - 2.2e-34 118.4 9.7 1.9e-33 115.4 6.5 4.2 4 0 0 4 4 4 3 Ion channel regulatory protein UNC-93 Csm1_N PF18504.1 CBY30862.1 - 0.0031 17.8 7.3 0.0031 17.8 7.3 2.0 1 1 1 2 2 2 1 Csm1 N-terminal domain GAS PF13851.6 CBY30862.1 - 0.0072 15.7 11.8 0.0091 15.4 11.8 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 CBY30862.1 - 0.014 15.6 8.2 0.017 15.4 8.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 USP8_interact PF08941.10 CBY30862.1 - 0.03 14.1 4.4 0.039 13.8 4.4 1.2 1 0 0 1 1 1 0 USP8 interacting FapA PF03961.13 CBY30862.1 - 0.042 12.5 6.0 0.049 12.2 6.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-K PF11802.8 CBY30862.1 - 0.047 13.3 7.1 0.056 13.0 7.1 1.0 1 0 0 1 1 1 0 Centromere-associated protein K DUF4763 PF15960.5 CBY30862.1 - 0.058 12.7 12.0 0.22 10.8 11.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Swi5 PF07061.11 CBY30862.1 - 0.06 13.4 5.9 0.095 12.8 5.9 1.4 1 0 0 1 1 1 0 Swi5 PRKG1_interact PF15898.5 CBY30862.1 - 0.061 14.2 6.4 0.086 13.7 6.4 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Ribosomal_S3Ae PF01015.18 CBY30862.1 - 0.065 12.8 1.5 0.078 12.5 1.5 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family DUF2570 PF10828.8 CBY30862.1 - 0.085 12.7 7.9 0.11 12.3 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cep57_MT_bd PF06657.13 CBY30862.1 - 0.3 11.6 9.5 2.3 8.7 4.4 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Cnn_1N PF07989.11 CBY30862.1 - 0.54 10.5 10.9 1.5 9.0 4.7 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Sec2p PF06428.11 CBY30862.1 - 0.57 10.2 13.7 0.45 10.5 7.4 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TMPIT PF07851.13 CBY30862.1 - 0.93 8.7 4.5 1 8.5 4.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 CBY30862.1 - 1.2 9.8 9.4 4 8.1 2.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 CBY30862.1 - 1.8 9.1 9.8 2.4 8.7 2.2 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 CBY30862.1 - 3.1 7.0 12.4 1.9 7.7 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DASH_Spc34 PF08657.10 CBY30862.1 - 8.4 6.1 11.5 11 5.8 11.5 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 SlyX PF04102.12 CBY30862.1 - 9.6 6.9 13.9 74 4.1 13.9 2.0 1 1 0 1 1 1 0 SlyX Trypsin PF00089.26 CBY30865.1 - 1.1e-37 129.9 0.1 1.1e-37 129.9 0.1 1.7 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY30865.1 - 2.4e-05 24.7 0.0 7.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) UPAR_LY6_2 PF16975.5 CBY30865.1 - 0.0071 16.5 10.7 0.0071 16.5 10.7 1.7 2 0 0 2 2 2 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Aldose_epim PF01263.20 CBY30869.1 - 1e-79 268.0 0.0 1.3e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Sulfotransfer_1 PF00685.27 CBY30870.1 - 7.3e-09 35.5 0.8 1.2e-08 34.8 0.1 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY30870.1 - 6e-05 23.5 0.1 0.00032 21.2 0.0 2.2 3 0 0 3 3 3 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY30870.1 - 0.00038 20.4 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family GerD PF17898.1 CBY30870.1 - 0.013 15.4 1.0 0.036 14.0 0.2 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF573 PF04504.14 CBY30870.1 - 0.029 15.0 0.8 0.091 13.4 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF1689 PF07954.11 CBY30870.1 - 0.082 13.3 0.5 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Connexin PF00029.19 CBY30871.1 - 8e-29 101.0 1.0 1e-28 100.7 1.0 1.0 1 0 0 1 1 1 1 Connexin EMC3_TMCO1 PF01956.16 CBY30871.1 - 0.011 15.5 0.4 0.022 14.5 0.1 1.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Peptidase_S49_N PF08496.10 CBY30871.1 - 0.025 14.6 2.7 0.025 14.6 2.7 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Orf78 PF06024.12 CBY30871.1 - 0.048 14.0 1.3 0.058 13.7 0.1 1.7 2 0 0 2 2 2 0 Orf78 (ac78) UL45 PF05473.12 CBY30871.1 - 0.049 13.3 0.1 0.099 12.3 0.0 1.5 1 1 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like ATP-synt_E PF05680.12 CBY30871.1 - 0.083 13.2 3.3 0.12 12.7 3.3 1.2 1 0 0 1 1 1 0 ATP synthase E chain Pox_EPC_I2-L1 PF12575.8 CBY30871.1 - 0.14 12.4 1.6 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF3040 PF11239.8 CBY30871.1 - 0.21 11.9 0.6 1.8 8.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Casc1_N PF15927.5 CBY30871.1 - 3.3 7.3 12.7 4.9 6.8 12.7 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Connexin PF00029.19 CBY30872.1 - 1.7e-27 96.7 0.2 1.9e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 Connexin FCH PF00611.23 CBY30872.1 - 0.0084 16.4 2.1 0.014 15.7 2.1 1.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DndB PF14072.6 CBY30872.1 - 0.11 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated Phospholip_A2_1 PF00068.19 CBY30873.1 - 1.8e-16 60.6 4.3 1.8e-16 60.6 4.3 1.8 2 0 0 2 2 2 1 Phospholipase A2 DEK_C PF08766.11 CBY30874.1 - 9.3e-11 41.5 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 DEK C terminal domain NOT2_3_5 PF04153.18 CBY30874.1 - 0.12 12.4 0.4 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family F-box-like PF12937.7 CBY30876.1 - 1.9e-06 27.7 0.1 3.9e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 CBY30876.1 - 1e-05 25.2 0.5 2.1e-05 24.2 0.5 1.6 1 0 0 1 1 1 1 BTK motif F-box PF00646.33 CBY30876.1 - 0.00046 20.0 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain Trypsin PF00089.26 CBY30877.1 - 1.3e-104 348.9 1.2 5.4e-59 199.7 0.1 2.1 2 0 0 2 2 2 2 Trypsin Trypsin_2 PF13365.6 CBY30877.1 - 2.6e-13 51.1 0.0 1.8e-07 32.2 0.0 2.2 2 0 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY30877.1 - 3.6e-07 30.6 0.0 0.00076 19.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Histone PF00125.24 CBY30878.1 - 7.6e-54 181.6 1.6 8.5e-54 181.4 1.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY30878.1 - 7.9e-05 22.7 0.2 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY30878.1 - 0.00015 22.3 2.4 0.00019 22.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY30878.1 - 0.00028 21.2 0.0 0.00042 20.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY30878.1 - 0.054 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glycos_transf_2 PF00535.26 CBY30880.1 - 5.8e-15 55.5 0.0 9.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY30880.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 zf-C2H2 PF00096.26 CBY30881.1 - 0.00085 19.7 3.8 0.0017 18.7 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 CBY30881.1 - 0.089 13.4 0.1 0.15 12.7 0.1 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CBY30881.1 - 0.11 13.4 2.7 0.19 12.6 2.7 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Coiled-coil_56 PF09813.9 CBY30883.1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 Trypsin PF00089.26 CBY30885.1 - 2e-52 178.2 0.6 3.2e-52 177.6 0.6 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY30885.1 - 1.4e-06 29.3 0.0 3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain SelR PF01641.18 CBY30886.1 - 2.7e-38 130.7 0.6 3.3e-38 130.5 0.6 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CBY30886.1 - 0.00069 19.8 1.1 0.0019 18.4 1.1 1.6 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.14 CBY30886.1 - 0.095 13.1 2.2 0.66 10.3 2.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ta0938 PF11494.8 CBY30886.1 - 0.11 12.8 1.2 0.42 10.9 0.2 2.1 1 1 0 2 2 2 0 Ta0938 DUF2225 PF09986.9 CBY30886.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Auto_anti-p27 PF06677.12 CBY30886.1 - 0.21 11.7 3.3 3.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MFS_1 PF07690.16 CBY30888.1 - 7.3e-11 41.6 23.2 3.9e-10 39.2 15.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 CBY30888.1 - 0.071 13.6 8.4 0.27 11.7 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Glyco_transf_10 PF00852.19 CBY30889.1 - 2.4e-43 147.9 0.1 4.9e-43 146.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY30889.1 - 2.8e-16 60.0 0.3 5.7e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Leader_CPA1 PF08252.11 CBY30889.1 - 0.015 14.6 0.1 0.04 13.3 0.1 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide PhoPQ_related PF10142.9 CBY30890.1 - 3.6e-99 331.9 0.3 4.8e-99 331.5 0.3 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein IDO PF01231.18 CBY30891.1 - 4.5e-96 322.3 0.0 5.5e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RRXRR PF14239.6 CBY30893.1 - 0.018 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 RRXRR protein Red1 PF07964.11 CBY30893.1 - 0.081 11.2 5.1 0.1 10.8 5.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 IMUP PF15761.5 CBY30894.1 - 0.015 16.0 5.3 0.027 15.2 5.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 CBY30894.1 - 2.4 8.5 14.2 4.2 7.7 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2457 PF10446.9 CBY30894.1 - 2.4 7.2 13.2 3.2 6.8 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lipocalin_7 PF14651.6 CBY30895.1 - 0.056 13.4 0.9 0.13 12.2 0.9 1.6 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family MFS_1 PF07690.16 CBY30896.1 - 0.0013 17.7 0.7 0.0013 17.7 0.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA_int_endo PF01974.17 CBY30896.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain 2TM PF13239.6 CBY30896.1 - 0.19 12.1 0.2 0.19 12.1 0.2 2.0 2 0 0 2 2 2 0 2TM domain DUF3784 PF12650.7 CBY30896.1 - 0.23 11.7 3.6 0.42 10.8 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF3413 PF11893.8 CBY30896.1 - 0.27 10.3 3.7 0.13 11.4 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) EF-hand_4 PF12763.7 CBY30897.1 - 4.5e-29 100.4 0.0 2.3e-19 69.2 0.1 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY30897.1 - 2.9e-08 32.7 0.0 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY30897.1 - 0.00015 21.4 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain CENP-F_leu_zip PF10473.9 CBY30897.1 - 0.00072 19.6 10.2 0.00072 19.6 10.2 2.3 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_7 PF13499.6 CBY30897.1 - 0.00077 19.9 0.0 2.2 8.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair APG6_N PF17675.1 CBY30897.1 - 0.0011 19.5 11.3 0.0011 19.5 11.3 2.6 2 1 1 3 3 2 1 Apg6 coiled-coil region EF-hand_8 PF13833.6 CBY30897.1 - 0.0042 16.9 0.0 0.22 11.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair DUF3450 PF11932.8 CBY30897.1 - 0.0063 15.8 3.6 0.0063 15.8 3.6 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Filament PF00038.21 CBY30897.1 - 0.018 14.6 9.1 0.088 12.4 9.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein EF-hand_5 PF13202.6 CBY30897.1 - 0.023 14.2 1.9 0.47 10.0 0.2 2.5 2 0 0 2 2 2 0 EF hand Golgin_A5 PF09787.9 CBY30897.1 - 0.036 13.6 10.2 0.06 12.8 10.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5082 PF16888.5 CBY30897.1 - 0.039 14.2 6.7 0.48 10.7 6.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 CBY30897.1 - 0.039 14.2 9.6 0.61 10.4 1.7 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 CBY30897.1 - 0.089 13.0 8.0 0.37 11.0 1.3 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.11 CBY30897.1 - 0.096 11.5 14.4 0.15 10.9 14.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 CBY30897.1 - 0.097 13.1 12.6 0.15 12.5 12.6 1.2 1 0 0 1 1 1 0 Fez1 DUF4797 PF16051.5 CBY30897.1 - 0.11 12.4 3.8 3.1 7.8 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) ADIP PF11559.8 CBY30897.1 - 0.13 12.3 9.4 2 8.5 5.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CBY30897.1 - 0.19 10.6 11.9 0.33 9.8 11.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 CBY30897.1 - 0.19 10.2 3.4 0.27 9.8 3.4 1.3 1 0 0 1 1 1 0 Macoilin family TPR_MLP1_2 PF07926.12 CBY30897.1 - 0.25 11.4 12.2 0.59 10.2 12.2 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CBY30897.1 - 0.37 11.0 10.7 1.2 9.4 5.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3138 PF11336.8 CBY30897.1 - 0.4 9.2 1.7 0.68 8.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) kleA_kleC PF17383.2 CBY30897.1 - 0.56 10.6 3.4 1.5 9.2 0.4 2.8 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A AAA_13 PF13166.6 CBY30897.1 - 0.68 8.5 4.3 1.5 7.4 4.1 1.4 1 1 0 1 1 1 0 AAA domain DUF724 PF05266.14 CBY30897.1 - 1.4 8.7 6.6 0.63 9.8 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RasGAP_C PF03836.15 CBY30897.1 - 1.4 9.1 4.6 0.39 10.9 1.3 1.7 2 0 0 2 2 1 0 RasGAP C-terminus DUF2730 PF10805.8 CBY30897.1 - 1.4 9.0 3.7 2.4 8.3 0.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 CBY30897.1 - 1.9 7.8 9.4 4.3 6.6 9.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 CBY30897.1 - 2.2 7.4 4.1 3.3 6.9 4.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.6 CBY30897.1 - 4.4 6.6 13.4 0.89 8.9 7.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.6 CBY30897.1 - 4.4 6.8 12.4 8.4 5.9 11.8 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 CBY30897.1 - 5.1 7.8 10.0 7.9 7.2 4.4 3.3 1 1 2 3 3 3 0 SlyX FlaC_arch PF05377.11 CBY30897.1 - 5.2 7.6 5.8 9.5 6.7 0.4 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 CBY30897.1 - 6 5.3 9.8 8.1 4.8 9.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_1 PF00515.28 CBY30898.1 - 1.3e-13 50.1 0.1 4.6e-07 29.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY30898.1 - 1.2e-10 40.7 0.2 9.4e-06 25.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY30898.1 - 7.3e-06 25.8 9.2 5.1e-05 23.2 0.2 4.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY30898.1 - 1.9e-05 24.9 0.1 0.00023 21.4 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY30898.1 - 2.8e-05 24.5 2.0 0.23 12.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY30898.1 - 0.00011 22.8 0.0 0.059 14.0 0.0 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBY30898.1 - 0.0017 18.1 1.5 0.0073 16.2 0.1 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY30898.1 - 0.0029 18.3 1.7 0.24 12.3 0.0 3.7 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY30898.1 - 0.0052 16.7 0.1 0.072 13.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat mCpol PF18182.1 CBY30898.1 - 0.0086 16.4 2.0 2.1 8.7 0.4 3.0 2 0 0 2 2 2 1 minimal CRISPR polymerase domain HEAT_EZ PF13513.6 CBY30898.1 - 0.01 16.3 0.6 0.3 11.6 0.0 3.7 4 1 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 CBY30898.1 - 0.026 14.9 0.7 6.4 7.2 0.0 4.0 3 1 0 4 4 4 0 HEAT repeats TPR_11 PF13414.6 CBY30898.1 - 0.072 12.8 0.9 23 4.7 0.1 3.5 3 1 1 4 4 4 0 TPR repeat TPR_17 PF13431.6 CBY30898.1 - 0.075 13.4 0.0 31 5.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY30898.1 - 0.08 13.1 0.0 3 8.0 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY30898.1 - 0.097 13.4 1.9 0.62 10.8 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat HEAT PF02985.22 CBY30898.1 - 0.11 12.8 0.7 78 3.9 0.0 4.3 5 0 0 5 5 3 0 HEAT repeat Arm PF00514.23 CBY30898.1 - 0.33 11.0 4.4 0.63 10.2 0.0 3.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cyclin_N PF00134.23 CBY30899.1 - 1.2e-18 67.1 0.9 2.2e-18 66.2 0.9 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3839 PF12943.7 CBY30899.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) MFS_1 PF07690.16 CBY30901.1 - 4.9e-58 196.7 22.0 4.9e-58 196.7 22.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY30901.1 - 1.1e-09 37.7 6.4 1.1e-09 37.7 6.4 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBY30901.1 - 1.4e-06 27.9 2.1 1.4e-06 27.9 2.1 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 CBY30901.1 - 0.0076 14.8 11.5 0.0066 15.1 2.6 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 CBY30901.1 - 0.011 14.1 3.8 0.12 10.5 0.2 2.7 3 0 0 3 3 3 0 BT1 family Ank_2 PF12796.7 CBY30902.1 - 3.5e-20 72.4 0.0 2.9e-11 43.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY30902.1 - 1.1e-17 62.2 0.1 5.4e-05 23.3 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBY30902.1 - 5.6e-15 55.0 3.7 4e-05 23.9 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY30902.1 - 4.2e-14 52.4 1.6 5.1e-07 29.8 0.1 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY30902.1 - 8.2e-13 48.6 0.9 8.3e-10 39.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Trypsin PF00089.26 CBY30904.1 - 4.5e-48 164.0 0.3 5.4e-48 163.7 0.3 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY30904.1 - 1.2e-05 26.2 0.1 4.2e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY30904.1 - 0.055 13.0 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Methyltransf_23 PF13489.6 CBY30905.1 - 8.5e-18 64.7 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY30905.1 - 2.5e-17 63.4 0.0 5.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY30905.1 - 2.4e-16 60.1 0.0 4.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY30905.1 - 3.1e-16 59.5 0.1 5.2e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CBY30905.1 - 5.3e-14 52.3 0.0 7.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY30905.1 - 4.6e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY30905.1 - 1.3e-12 47.6 0.2 5.1e-12 45.6 0.1 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 CBY30905.1 - 3.1e-09 36.6 0.3 1.1e-07 31.5 0.0 2.8 2 1 1 3 3 3 1 CheR methyltransferase, SAM binding domain PrmA PF06325.13 CBY30905.1 - 9.4e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBY30905.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CBY30905.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 CBY30905.1 - 0.0083 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CBY30905.1 - 0.011 15.3 0.2 0.027 14.0 0.2 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 CBY30905.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 CBY30905.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MAP65_ASE1 PF03999.12 CBY30905.1 - 0.042 12.6 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UPF0020 PF01170.18 CBY30905.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 CBY30905.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4521 PF15021.6 CBY30906.1 - 0.0016 18.4 0.1 0.0019 18.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4521) DUF4381 PF14316.6 CBY30906.1 - 0.017 15.4 0.0 0.019 15.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RVT_1 PF00078.27 CBY30910.1 - 2.4e-15 56.7 0.0 2.4e-11 43.6 0.0 2.7 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MIT_C PF16565.5 CBY30911.1 - 0.015 15.2 1.3 2.4 8.1 0.9 2.4 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT Syntaxin PF00804.25 CBY30911.1 - 0.61 9.7 9.2 1.2 8.8 9.2 1.5 1 0 0 1 1 1 0 Syntaxin Recep_L_domain PF01030.24 CBY30912.1 - 0.071 13.2 1.0 0.44 10.7 0.6 2.0 2 0 0 2 2 2 0 Receptor L domain p450 PF00067.22 CBY30914.1 - 6.6e-56 190.0 0.0 9e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLN_propep PF16485.5 CBY30915.1 - 0.083 12.6 0.2 0.083 12.6 0.2 1.5 2 0 0 2 2 2 0 Protealysin propeptide DUF1179 PF06678.11 CBY30915.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) SH3BP5 PF05276.14 CBY30916.1 - 2.5e-28 99.5 14.4 2.5e-28 99.5 14.4 2.3 3 0 0 3 3 3 1 SH3 domain-binding protein 5 (SH3BP5) YabA PF06156.13 CBY30916.1 - 0.0029 18.2 0.5 0.0029 18.2 0.5 3.5 4 1 0 4 4 4 1 Initiation control protein YabA TPR_MLP1_2 PF07926.12 CBY30916.1 - 0.012 15.6 1.7 0.012 15.6 1.7 4.4 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein Tyrosinase PF00264.20 CBY30916.1 - 0.026 14.8 5.2 0.013 15.8 2.4 1.8 1 1 1 2 2 2 0 Common central domain of tyrosinase TSC22 PF01166.18 CBY30916.1 - 0.049 13.9 1.0 0.049 13.9 1.0 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family MR_MLE_N PF02746.16 CBY30916.1 - 0.15 12.3 0.1 5.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DivIC PF04977.15 CBY30916.1 - 0.26 11.1 13.2 0.18 11.6 0.9 4.0 4 1 0 4 4 4 0 Septum formation initiator DUF3488 PF11992.8 CBY30916.1 - 0.51 9.2 2.3 6.6 5.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Myb_DNA-bind_3 PF12776.7 CBY30916.1 - 4.1 8.5 7.0 28 5.8 0.9 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain HALZ PF02183.18 CBY30916.1 - 6.7 7.0 12.8 0.12 12.6 2.4 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper PetG PF02529.15 CBY30917.1 - 0.051 13.4 0.8 0.051 13.4 0.8 1.6 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Complex1_LYR PF05347.15 CBY30918.1 - 0.19 11.8 1.7 0.26 11.4 0.9 1.6 2 0 0 2 2 2 0 Complex 1 protein (LYR family) LNS2 PF08235.13 CBY30919.1 - 6.1e-07 29.1 0.1 8.2e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF1474 PF07342.11 CBY30919.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) GST_N PF02798.20 CBY30920.1 - 6.8e-07 29.5 0.0 2.1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CBY30920.1 - 0.00083 20.1 0.0 0.0016 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 CBY30920.1 - 0.00087 19.6 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY30920.1 - 0.0049 17.0 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY30920.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AAA_21 PF13304.6 CBY30921.1 - 1e-05 25.5 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CBY30921.1 - 0.00034 21.1 0.0 0.00049 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF4162 PF13732.6 CBY30922.1 - 0.0011 19.6 0.0 0.0013 19.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) MFS_1 PF07690.16 CBY30924.1 - 0.00042 19.3 8.5 0.00042 19.3 8.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Kelch_4 PF13418.6 CBY30925.1 - 4.6 7.3 9.4 31 4.7 0.1 4.5 4 0 0 4 4 4 0 Galactose oxidase, central domain CBP4 PF07960.11 CBY30926.1 - 0.032 14.1 0.2 0.072 12.9 0.2 1.5 1 0 0 1 1 1 0 CBP4 RT_RNaseH_2 PF17919.1 CBY30926.1 - 0.086 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Glyco_transf_10 PF00852.19 CBY30927.1 - 4.5e-25 88.4 2.0 4.5e-17 62.3 0.7 2.6 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY30927.1 - 6.2e-13 49.2 0.3 2.9e-12 47.0 0.2 2.2 1 1 1 2 2 2 1 Fucosyltransferase, N-terminal DUF4317 PF14199.6 CBY30927.1 - 0.017 14.3 1.6 0.025 13.7 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4317) Glyco_transf_10 PF00852.19 CBY30928.1 - 6.7e-12 45.5 0.1 1.5e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY30928.1 - 8.4e-12 45.5 0.0 1.7e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Lectin_C PF00059.21 CBY30930.1 - 0.011 16.4 1.9 0.011 16.4 1.9 2.3 1 1 1 2 2 2 0 Lectin C-type domain COesterase PF00135.28 CBY30931.1 - 3.4e-83 280.3 0.0 4.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY30931.1 - 7.5e-13 48.8 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY30931.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PilJ_C PF18223.1 CBY30931.1 - 0.013 15.9 0.6 0.54 10.8 0.1 3.0 3 0 0 3 3 3 0 Pili PilJ C-terminal domain Say1_Mug180 PF10340.9 CBY30931.1 - 0.051 12.4 0.0 7.5 5.3 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase DHODB_Fe-S_bind PF10418.9 CBY30932.1 - 0.017 15.0 6.0 2.2 8.2 0.1 4.2 4 0 0 4 4 4 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NPBW PF15180.6 CBY30932.1 - 0.13 12.1 0.9 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Neuropeptides B and W Glyco_transf_49 PF13896.6 CBY30934.1 - 4.9e-36 124.7 0.0 6.3e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 CBY30935.1 - 1.3e-16 60.9 0.5 1.3e-16 60.9 0.5 1.4 2 0 0 2 2 2 1 Glycosyl-transferase for dystroglycan MAM PF00629.23 CBY30936.1 - 5.5e-06 26.4 0.2 9.3e-06 25.6 0.2 1.4 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu adh_short PF00106.25 CBY30938.1 - 1.1e-35 122.9 0.1 1.3e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY30938.1 - 2.4e-22 79.6 0.1 3.1e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 CBY30938.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 CBY30938.1 - 0.003 17.5 0.0 0.0042 17.0 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CBY30938.1 - 0.017 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 CBY30938.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VCBS PF13517.6 CBY30939.1 - 1.3e-12 48.1 11.0 0.00073 20.1 0.0 3.8 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY30939.1 - 0.00033 20.7 11.7 0.066 13.4 1.3 4.1 4 0 0 4 4 4 3 FG-GAP repeat Xlink PF00193.17 CBY30939.1 - 0.2 12.1 4.2 0.14 12.5 0.5 2.3 1 1 0 2 2 2 0 Extracellular link domain CUB PF00431.20 CBY30940.1 - 7.5e-48 161.5 7.0 9e-17 61.4 0.2 3.5 3 0 0 3 3 3 3 CUB domain Trypsin PF00089.26 CBY30940.1 - 2.4e-45 155.0 1.1 5.1e-45 154.0 1.1 1.6 1 0 0 1 1 1 1 Trypsin Astacin PF01400.24 CBY30940.1 - 1.6e-11 44.2 0.0 4.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF1986 PF09342.11 CBY30940.1 - 0.13 12.6 0.2 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY30940.1 - 0.22 11.5 7.6 4.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Mur_ligase_M PF08245.12 CBY30941.1 - 6e-08 32.9 0.0 2.3e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CBY30941.1 - 0.064 13.5 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain zf-LSD1 PF06943.12 CBY30941.1 - 1.6 8.7 6.0 0.5 10.3 2.8 1.9 2 0 0 2 2 2 0 LSD1 zinc finger EGF_CA PF07645.15 CBY30942.1 - 1.9e-13 50.4 21.4 1.7e-09 37.7 8.5 10.3 8 4 1 9 9 9 4 Calcium-binding EGF domain EGF PF00008.27 CBY30942.1 - 8e-08 32.4 28.9 2.6e-06 27.6 4.8 10.0 9 3 2 11 11 11 4 EGF-like domain cEGF PF12662.7 CBY30942.1 - 1.3e-05 25.0 0.8 1.3e-05 25.0 0.8 8.0 8 1 0 8 8 8 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY30942.1 - 0.00017 21.7 19.3 0.00079 19.6 4.0 9.8 9 3 1 10 10 10 4 EGF domain hEGF PF12661.7 CBY30942.1 - 0.01 16.5 22.5 0.028 15.1 4.2 10.4 13 1 0 13 13 13 0 Human growth factor-like EGF Kelch_2 PF07646.15 CBY30943.1 - 0.0048 16.8 0.1 1.1 9.4 0.1 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY30943.1 - 0.011 15.3 1.7 0.43 10.2 0.1 3.1 2 1 0 2 2 2 0 Kelch motif eIF2A PF08662.11 CBY30943.1 - 0.047 13.6 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.6 CBY30943.1 - 0.05 13.9 0.1 4.4 7.7 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 CBY30943.1 - 0.065 13.3 1.8 5.6 7.1 0.2 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Pet191_N PF10203.9 CBY30944.1 - 0.011 16.1 1.0 0.011 16.1 1.0 3.6 4 0 0 4 4 4 0 Cytochrome c oxidase assembly protein PET191 Methyltransf_31 PF13847.6 CBY30945.1 - 1.8e-23 83.0 0.1 2.6e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY30945.1 - 1.9e-22 79.8 0.0 2.6e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY30945.1 - 1.3e-20 73.9 0.0 3.2e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY30945.1 - 5.7e-20 71.8 0.0 1.3e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY30945.1 - 3.3e-15 56.1 0.2 1.2e-14 54.2 0.1 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CBY30945.1 - 4.1e-15 55.8 0.2 5e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBY30945.1 - 3.3e-13 50.2 0.1 7e-13 49.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 CBY30945.1 - 1.4e-08 34.8 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CBY30945.1 - 5.4e-08 32.6 0.0 1.3e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 CBY30945.1 - 1.1e-07 31.4 0.2 3.1e-07 30.0 0.1 1.6 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.12 CBY30945.1 - 9e-06 25.4 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 CBY30945.1 - 9.8e-06 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 CBY30945.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CBY30945.1 - 4.1e-05 23.6 0.0 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY30945.1 - 0.0033 17.0 0.1 0.0051 16.4 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DOT1 PF08123.13 CBY30945.1 - 0.0049 16.4 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MetW PF07021.12 CBY30945.1 - 0.0055 16.3 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 CBY30945.1 - 0.0059 16.7 0.0 2.3 8.3 0.0 2.3 1 1 1 2 2 2 1 FtsJ-like methyltransferase CheR PF01739.18 CBY30945.1 - 0.011 15.2 0.0 0.049 13.1 0.0 1.9 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_5 PF01795.19 CBY30945.1 - 0.025 14.1 0.0 0.13 11.7 0.1 1.9 1 1 1 2 2 2 0 MraW methylase family UPF0020 PF01170.18 CBY30945.1 - 0.027 14.1 0.1 0.051 13.3 0.1 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 CBY30945.1 - 0.14 11.6 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase AGTRAP PF06396.11 CBY30946.1 - 9.3e-23 80.7 0.1 1.1e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) zf-RING_2 PF13639.6 CBY30947.1 - 2.4e-08 34.2 7.7 2.4e-08 34.2 7.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY30947.1 - 0.00081 19.1 8.9 0.0018 18.0 8.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBY30947.1 - 0.00084 18.9 6.0 0.00084 18.9 6.0 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CBY30947.1 - 0.003 17.4 7.9 0.003 17.4 7.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY30947.1 - 0.01 16.1 14.5 0.018 15.3 8.2 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain RNF220 PF15926.5 CBY30947.1 - 0.012 15.2 0.7 0.015 14.9 0.7 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 FANCL_C PF11793.8 CBY30947.1 - 0.027 14.6 10.6 0.052 13.7 7.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 CBY30947.1 - 0.065 13.6 10.1 0.085 13.2 5.1 2.3 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 CBY30947.1 - 0.95 9.6 9.7 0.3 11.3 6.0 2.1 2 1 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.6 CBY30947.1 - 6.2 6.9 15.9 0.079 13.0 7.7 2.0 2 1 0 2 2 2 0 RING-type zinc-finger PDZ PF00595.24 CBY30948.1 - 1.1e-12 48.1 0.7 2.3e-12 47.1 0.7 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY30948.1 - 0.0013 18.5 0.1 0.0032 17.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY30948.1 - 0.082 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 PDZ domain DUF4472 PF14739.6 CBY30948.1 - 3.7 8.3 14.0 0.72 10.6 0.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) CENP-H PF05837.12 CBY30948.1 - 6 7.3 12.5 5 7.6 6.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 CBY30948.1 - 6.4 6.5 19.1 0.17 11.7 4.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spectrin PF00435.21 CBY30949.1 - 1.1e-27 96.6 1.7 6.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Spectrin repeat EFhand_Ca_insen PF08726.10 CBY30949.1 - 1.4e-26 92.4 0.0 9.7e-26 89.7 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_1 PF00036.32 CBY30949.1 - 2.6e-08 32.8 0.0 0.0035 16.8 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY30949.1 - 2.7e-07 30.9 0.0 1e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY30949.1 - 2.6e-06 27.2 0.1 0.00094 19.0 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY30949.1 - 3.1e-06 26.7 0.2 0.0054 16.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain UPF0242 PF06785.11 CBY30949.1 - 0.024 14.7 1.9 0.045 13.9 1.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XisI PF08869.11 CBY30949.1 - 0.068 13.5 0.6 0.23 11.8 0.6 1.9 1 0 0 1 1 1 0 XisI protein FAA_hydrolase PF01557.18 CBY30949.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family DUF1845 PF08900.11 CBY30949.1 - 0.13 12.0 0.9 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) ApbA_C PF08546.11 CBY30949.1 - 0.13 12.5 0.1 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF5087 PF17006.5 CBY30949.1 - 0.15 11.5 0.3 0.63 9.5 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5087) CH PF00307.31 CBY30950.1 - 8.2e-50 167.6 0.1 2.9e-25 88.6 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain Spectrin PF00435.21 CBY30950.1 - 1.1e-10 41.9 0.8 2e-10 41.1 0.2 1.8 2 0 0 2 2 2 1 Spectrin repeat CAMSAP_CH PF11971.8 CBY30950.1 - 1.8e-07 30.9 0.1 7e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 CAMSAP CH domain UNC-93 PF05978.16 CBY30951.1 - 4.6e-21 75.2 9.6 4.6e-21 75.2 9.6 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY30951.1 - 1.4e-05 24.2 40.0 2.9e-05 23.2 35.2 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3098 PF11297.8 CBY30951.1 - 0.005 16.4 0.7 0.026 14.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3098) DUF5349 PF17298.2 CBY30951.1 - 0.27 11.0 9.0 0.4 10.4 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) FAM198 PF15051.6 CBY30952.1 - 0.1 11.5 0.2 0.13 11.1 0.2 1.0 1 0 0 1 1 1 0 FAM198 protein Xlink PF00193.17 CBY30952.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Extracellular link domain Sulfatase PF00884.23 CBY30955.1 - 4.4e-47 161.0 0.2 1.3e-23 83.9 0.1 2.4 2 0 0 2 2 2 2 Sulfatase Phosphodiest PF01663.22 CBY30955.1 - 1e-05 25.3 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ASL_C2 PF14698.6 CBY30955.1 - 0.11 13.2 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal ARD PF03079.14 CBY30956.1 - 3.9e-44 150.6 0.1 4.7e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CBY30956.1 - 4.2e-07 29.6 0.0 7.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CBY30956.1 - 0.00092 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CBY30956.1 - 0.045 13.4 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 CBY30956.1 - 0.045 13.5 0.0 0.086 12.5 0.0 1.7 1 1 0 1 1 1 0 Cupin-like domain MgtE PF01769.16 CBY30957.1 - 9e-46 155.3 28.9 1.3e-24 86.9 4.2 3.0 4 0 0 4 4 4 2 Divalent cation transporter RasGEF PF00617.19 CBY30958.1 - 2.3e-45 155.0 0.1 4.6e-45 154.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CBY30958.1 - 1.8e-19 69.9 0.4 6.9e-19 68.0 0.4 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RA PF00788.23 CBY30958.1 - 1.8e-09 38.1 0.0 4.8e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Glyco_hydro38C2 PF17677.1 CBY30958.1 - 0.011 15.8 0.4 0.062 13.4 0.3 2.5 2 1 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PGI PF00342.19 CBY30959.1 - 3.4e-211 702.0 8.7 8.3e-120 400.6 0.3 2.0 1 1 1 2 2 2 2 Phosphoglucose isomerase Pkinase PF00069.25 CBY30960.1 - 9e-61 205.5 0.0 1.1e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30960.1 - 9.7e-39 133.2 0.0 1.2e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY30960.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY30960.1 - 2.2e-05 23.6 0.1 3.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY30960.1 - 0.00044 19.7 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY30960.1 - 0.018 14.6 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CBY30960.1 - 0.19 11.6 0.1 0.9 9.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 CBY30961.1 - 8e-14 52.0 0.7 1.3e-10 41.8 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY30961.1 - 7.4e-09 35.1 0.1 0.039 14.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBY30961.1 - 1e-08 35.5 0.2 9.4e-08 32.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY30961.1 - 1.4e-07 31.6 0.1 0.0038 17.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Fez1 PF06818.15 CBY30961.1 - 1.2e-05 25.8 10.0 2.4e-05 24.9 10.0 1.4 1 0 0 1 1 1 1 Fez1 Ank PF00023.30 CBY30961.1 - 0.00017 21.9 0.0 0.4 11.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF4686 PF15742.5 CBY30961.1 - 0.0031 16.7 10.3 0.0055 15.9 10.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Polysacc_synt_2 PF02719.15 CBY30961.1 - 0.018 14.2 0.2 0.054 12.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DHR10 PF18595.1 CBY30961.1 - 0.023 14.7 4.0 0.023 14.7 4.0 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FAM76 PF16046.5 CBY30961.1 - 0.042 13.2 11.5 0.014 14.7 7.3 1.9 1 1 1 2 2 2 0 FAM76 protein SPATA1_C PF15743.5 CBY30961.1 - 0.043 13.9 8.7 0.086 12.9 8.7 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus ADIP PF11559.8 CBY30961.1 - 0.068 13.3 10.0 0.061 13.4 2.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CBY30961.1 - 0.11 11.4 11.2 0.18 10.6 11.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CBY30961.1 - 0.13 12.8 13.5 0.17 12.5 5.1 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 CBY30961.1 - 0.25 10.8 15.8 0.51 9.7 15.8 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 CBY30961.1 - 0.29 11.2 11.5 0.48 10.5 11.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CC2-LZ PF16516.5 CBY30961.1 - 0.6 10.5 11.3 1.6 9.1 11.4 1.8 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMPIT PF07851.13 CBY30961.1 - 0.72 9.0 4.4 1 8.5 4.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cep57_MT_bd PF06657.13 CBY30961.1 - 1.2 9.6 11.3 2.1 8.8 4.3 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ISG65-75 PF11727.8 CBY30961.1 - 1.3 8.2 7.2 2 7.6 1.4 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein SlyX PF04102.12 CBY30961.1 - 2 9.1 6.1 1.1 9.9 1.4 2.7 1 1 0 2 2 2 0 SlyX PhoU PF01895.19 CBY30961.1 - 2.6 8.6 9.0 4.9 7.7 1.3 3.4 3 0 0 3 3 3 0 PhoU domain NYD-SP28 PF14772.6 CBY30961.1 - 2.6 8.1 16.1 0.25 11.4 8.2 2.5 1 1 1 2 2 2 0 Sperm tail DUF1664 PF07889.12 CBY30961.1 - 2.8 8.0 6.6 18 5.4 6.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CBY30961.1 - 3.1 8.3 6.7 3.8 8.0 1.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 CBY30961.1 - 3.8 7.7 18.0 0.96 9.6 7.4 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.19 CBY30961.1 - 4.5 7.0 17.7 1.9 8.2 14.7 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF16 PF01519.16 CBY30961.1 - 5 7.7 10.5 6.8 7.2 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.15 CBY30961.1 - 8 6.3 13.2 0.86 9.4 2.2 3.0 2 1 0 3 3 3 0 Septum formation initiator SOGA PF11365.8 CBY30962.1 - 0.00084 20.4 2.1 0.00084 20.4 2.1 3.2 1 1 2 3 3 3 1 Protein SOGA DUF2576 PF10845.8 CBY30962.1 - 0.015 14.9 0.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) PRKG1_interact PF15898.5 CBY30962.1 - 0.046 14.6 16.8 0.072 14.0 7.9 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 CBY30962.1 - 0.059 13.7 11.1 6.5 7.2 0.2 4.0 3 2 1 4 4 4 0 TSC-22/dip/bun family BSD PF03909.17 CBY30962.1 - 0.073 13.1 0.8 3.6 7.7 0.1 3.3 1 1 2 3 3 3 0 BSD domain GAS PF13851.6 CBY30962.1 - 0.084 12.2 21.1 0.077 12.3 11.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KIAA1430 PF13879.6 CBY30962.1 - 0.19 12.5 12.7 0.39 11.5 3.7 2.5 1 1 1 2 2 2 0 KIAA1430 homologue DivIC PF04977.15 CBY30962.1 - 0.43 10.4 15.5 2.4 8.0 1.1 4.0 2 1 2 4 4 4 0 Septum formation initiator Fez1 PF06818.15 CBY30962.1 - 1.5 9.2 13.9 4.3 7.7 13.9 1.7 1 1 0 1 1 1 0 Fez1 Striatin PF08232.12 CBY30962.1 - 2.1 8.9 12.7 1.5 9.4 10.3 1.9 1 1 0 2 2 2 0 Striatin family YlqD PF11068.8 CBY30962.1 - 2.5 8.5 6.2 2.1 8.7 0.3 2.4 1 1 0 2 2 2 0 YlqD protein Sas10_Utp3 PF04000.15 CBY30962.1 - 7.8 7.2 11.2 0.34 11.5 2.1 2.7 2 1 0 2 2 2 0 Sas10/Utp3/C1D family bZIP_2 PF07716.15 CBY30962.1 - 8.2 6.6 15.6 13 6.0 0.9 4.1 4 0 0 4 4 4 0 Basic region leucine zipper ZapB PF06005.12 CBY30962.1 - 8.3 6.9 20.7 0.55 10.7 2.4 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.6 CBY30962.1 - 8.8 6.8 11.2 2.7 8.5 1.0 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) YebO PF13974.6 CBY30963.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.0 2 1 0 2 2 2 0 YebO-like protein CDC37_N PF03234.14 CBY30963.1 - 0.29 12.1 3.4 0.45 11.4 0.5 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding TSP_1 PF00090.19 CBY30964.1 - 7.6e-08 32.5 11.4 7.6e-08 32.5 11.4 3.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain SelP_N PF04592.14 CBY30965.1 - 1 8.7 12.3 1.5 8.2 12.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M14 PF00246.24 CBY30967.1 - 3.9e-75 253.3 0.0 5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBY30967.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Rotamase_2 PF13145.6 CBY30968.1 - 0.074 13.9 0.1 0.37 11.6 0.0 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain PLDc PF00614.22 CBY30969.1 - 6.2e-18 64.2 0.3 6.2e-08 32.5 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CBY30969.1 - 2.8e-15 56.4 0.2 1.1e-06 28.6 0.0 3.3 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.14 CBY30969.1 - 1.1e-10 41.0 1.0 4e-10 39.1 1.0 1.8 1 1 0 1 1 1 1 mTERF DASH_Ask1 PF08655.10 CBY30969.1 - 0.059 13.3 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Ask1 Ribosomal_L31e PF01198.19 CBY30970.1 - 4e-38 129.5 2.6 4e-38 129.5 2.6 1.5 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.17 CBY30971.1 - 1.3e-94 316.3 0.0 1.7e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Band_7 PF01145.25 CBY30971.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Tmemb_14 PF03647.13 CBY30972.1 - 1.3e-14 54.6 7.9 1.6e-14 54.4 7.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PigN PF04987.14 CBY30972.1 - 0.014 14.3 4.1 0.018 13.9 4.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TctB PF07331.11 CBY30972.1 - 3.8 7.8 10.0 12 6.2 10.0 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.18 CBY30973.1 - 2.4e-17 62.6 2.0 1.3e-15 57.1 1.4 2.3 2 0 0 2 2 2 2 NAC domain GDA1_CD39 PF01150.17 CBY30974.1 - 6.3e-112 374.3 0.0 8.9e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DPM3 PF08285.11 CBY30975.1 - 3.7e-13 49.5 1.1 4.1e-13 49.3 1.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DPM3 PF08285.11 CBY30976.1 - 0.0046 17.1 0.0 0.0054 16.9 0.0 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Adaptin_binding PF10199.9 CBY30977.1 - 2.1e-08 34.8 0.7 1.8e-07 31.8 0.7 2.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Roc PF08477.13 CBY30978.1 - 6.5e-08 32.8 0.0 9.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY30978.1 - 0.00062 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CBY30978.1 - 0.0025 17.9 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CBY30978.1 - 0.0047 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_4 PF13637.6 CBY30980.1 - 4.9e-31 106.7 0.5 1.7e-10 41.2 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY30980.1 - 1.5e-28 99.2 0.1 6.3e-14 52.3 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY30980.1 - 3.7e-27 94.0 0.1 3.8e-07 30.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY30980.1 - 6e-26 89.7 0.1 4e-08 33.4 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY30980.1 - 2.6e-22 76.5 0.1 6.3e-06 26.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat ARA70 PF12489.8 CBY30980.1 - 0.051 13.8 4.6 0.25 11.5 4.6 2.1 1 1 0 1 1 1 0 Nuclear coactivator NABP PF07990.12 CBY30980.1 - 0.061 12.9 1.7 0.1 12.1 1.7 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4407 PF14362.6 CBY30980.1 - 0.099 12.0 3.1 0.17 11.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3672 PF12421.8 CBY30980.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III protein ER PF01133.17 CBY30983.1 - 1.7e-42 143.4 0.7 1.9e-42 143.3 0.7 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary PBP_N PF17093.5 CBY30984.1 - 0.048 13.9 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus Calreticulin PF00262.18 CBY30985.1 - 5.9e-70 236.0 19.1 5.7e-51 173.5 9.0 2.7 2 1 1 3 3 3 2 Calreticulin family Pkinase PF00069.25 CBY30987.1 - 8.8e-29 100.7 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30987.1 - 1.5e-20 73.6 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPH PF13868.6 CBY30988.1 - 4.9e-43 147.0 97.1 6e-43 146.7 97.1 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain HJURP_mid PF12346.8 CBY30988.1 - 0.031 14.7 0.6 0.031 14.7 0.6 2.4 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat DUF1077 PF06417.12 CBY30990.1 - 1.8e-36 124.7 1.3 2.5e-36 124.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TPH PF13868.6 CBY30991.1 - 1.1e-26 93.3 78.9 1.1e-26 93.3 78.9 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain TPH PF13868.6 CBY30992.1 - 1e-21 76.9 34.0 1.2e-21 76.7 34.0 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Mt_ATP-synt_B PF05405.14 CBY30992.1 - 0.0084 15.7 5.7 0.011 15.3 5.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) eIF3_subunit PF08597.10 CBY30992.1 - 0.32 10.9 11.6 0.4 10.5 11.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Asp-B-Hydro_N PF05279.11 CBY30992.1 - 1.9 8.5 11.6 2.1 8.3 11.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4337 PF14235.6 CBY30992.1 - 3.1 7.9 9.5 4.1 7.5 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Sec62 PF03839.16 CBY30992.1 - 4 6.9 5.0 4.5 6.7 5.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TSP_1 PF00090.19 CBY30993.1 - 0.0015 18.7 9.5 0.0015 18.7 9.5 3.1 3 0 0 3 3 3 1 Thrombospondin type 1 domain Ephrin_rec_like PF07699.13 CBY30993.1 - 0.031 14.0 16.0 0.023 14.5 8.6 3.4 1 1 1 2 2 2 0 Putative ephrin-receptor like TPH PF13868.6 CBY30994.1 - 7.4e-42 143.1 95.0 8.3e-42 142.9 95.0 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Gsf2 PF11055.8 CBY30994.1 - 1.6 7.4 6.7 3.1 6.5 6.7 1.5 1 0 0 1 1 1 0 Glucose signalling factor 2 DUF4215 PF13948.6 CBY30995.1 - 0.57 10.7 6.6 1.4 9.4 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Ephrin_rec_like PF07699.13 CBY30995.1 - 1.4 8.8 20.2 0.047 13.5 8.8 2.7 2 1 1 3 3 3 0 Putative ephrin-receptor like Pkinase PF00069.25 CBY30997.1 - 8.1e-71 238.5 0.0 1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY30997.1 - 4.9e-34 117.8 0.0 7.4e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY30997.1 - 2.9e-08 33.4 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY30997.1 - 0.02 13.8 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Thioredoxin_2 PF13098.6 CBY30998.1 - 0.026 15.0 0.1 0.055 13.9 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain IL15 PF02372.15 CBY30998.1 - 0.066 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin 15 Tau95_N PF17682.1 CBY30998.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Tau95 Triple barrel domain DUF2847 PF11009.8 CBY30998.1 - 0.16 11.9 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Trefoil PF00088.18 CBY30999.1 - 2.4e-17 62.5 28.0 4.5e-13 48.9 8.0 2.6 2 0 0 2 2 2 2 Trefoil (P-type) domain Alpha-amylase PF00128.24 CBY30999.1 - 2.5e-10 40.4 0.0 6.8e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CBY30999.1 - 3.3e-09 37.1 0.0 1.8e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Sugar_tr PF00083.24 CBY31000.1 - 3.6e-21 75.5 0.6 4.8e-21 75.1 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY31000.1 - 2.4e-09 36.6 0.9 3e-09 36.3 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4110 PF13422.6 CBY31000.1 - 0.14 12.2 0.3 0.21 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Pox_P35 PF03213.14 CBY31000.1 - 0.47 9.6 3.1 0.39 9.9 1.8 1.5 1 1 1 2 2 2 0 Poxvirus P35 protein PAS_11 PF14598.6 CBY31001.1 - 3.6e-14 52.9 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY31001.1 - 2.3e-12 47.0 0.0 5.3e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 CBY31001.1 - 0.00036 20.5 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBY31001.1 - 0.0049 17.1 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain Flavodoxin_5 PF12724.7 CBY31001.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Kelch_2 PF07646.15 CBY31002.1 - 0.03 14.3 0.2 6.2 7.0 0.0 3.6 3 1 0 3 3 3 0 Kelch motif Syntaxin PF00804.25 CBY31004.1 - 2.5e-48 164.4 25.2 3.6e-48 163.9 25.2 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CBY31004.1 - 3.5e-12 46.1 0.2 3.5e-12 46.1 0.2 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 CBY31004.1 - 1.5e-07 31.7 17.2 1.5e-07 31.7 17.2 2.7 1 1 1 2 2 2 1 Syntaxin-like protein Baculo_PEP_C PF04513.12 CBY31004.1 - 0.02 14.9 11.7 0.061 13.4 5.7 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 CBY31004.1 - 0.021 14.6 14.2 0.2 11.5 0.8 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.21 CBY31004.1 - 0.022 15.2 13.8 0.65 10.5 7.2 2.5 2 0 0 2 2 2 0 Spectrin repeat COG5 PF10392.9 CBY31004.1 - 0.051 13.7 11.0 1.6 8.9 6.1 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Tricorn_C1 PF14684.6 CBY31004.1 - 0.057 13.5 0.5 1.9 8.6 0.0 2.6 2 1 0 2 2 2 0 Tricorn protease C1 domain DUF4226 PF10774.9 CBY31004.1 - 0.18 12.1 8.0 0.13 12.5 4.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) DSBA PF01323.20 CBY31004.1 - 0.18 11.6 2.8 0.21 11.3 1.9 1.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain DUF948 PF06103.11 CBY31004.1 - 0.2 12.0 10.4 9.1 6.6 4.5 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.8 CBY31004.1 - 0.22 10.7 10.8 0.054 12.7 6.9 1.9 1 1 0 2 2 2 0 Invariant surface glycoprotein LOH1CR12 PF10158.9 CBY31004.1 - 0.61 10.1 13.5 3.1 7.8 5.6 2.7 2 1 0 2 2 2 0 Tumour suppressor protein PRKG1_interact PF15898.5 CBY31004.1 - 0.71 10.8 23.4 2.5 9.1 2.6 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 CBY31004.1 - 1.3 9.1 21.3 1.6 8.8 3.6 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 CBY31004.1 - 1.7 9.0 9.2 3.3 8.0 1.8 3.6 2 2 2 4 4 4 0 Proteins of 100 residues with WXG Fzo_mitofusin PF04799.13 CBY31004.1 - 2.2 7.8 15.6 1.5 8.3 8.0 2.9 2 1 1 3 3 3 0 fzo-like conserved region DUF3800 PF12686.7 CBY31004.1 - 2.6 8.7 7.1 18 6.0 7.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Laminin_II PF06009.12 CBY31004.1 - 3.2 7.8 17.7 0.98 9.4 8.4 3.0 2 2 1 3 3 3 0 Laminin Domain II Erp_C PF06780.11 CBY31004.1 - 4.1 7.4 13.2 2.1 8.3 0.6 3.2 2 1 1 3 3 3 0 Erp protein C-terminus DUF883 PF05957.13 CBY31004.1 - 5 7.8 10.8 8.6 7.0 5.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Allexi_40kDa PF05549.11 CBY31004.1 - 6.1 6.3 13.9 1.4 8.4 6.9 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 CBY31004.1 - 8.8 6.9 15.4 1 9.9 4.5 3.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DnaI_N PF07319.11 CBY31008.1 - 0.2 12.4 0.4 0.76 10.5 0.0 2.1 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus LptF_LptG PF03739.14 CBY31008.1 - 1.4 7.7 4.7 7.1 5.4 4.7 2.0 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG GOLD_2 PF13897.6 CBY31009.1 - 7.1e-69 230.6 4.3 7.1e-69 230.6 4.3 2.7 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking Caldesmon PF02029.15 CBY31009.1 - 0.00054 18.9 19.0 0.00054 18.9 19.0 1.6 2 0 0 2 2 2 1 Caldesmon MAP7 PF05672.11 CBY31009.1 - 0.00085 19.0 41.4 0.00085 19.0 41.4 1.6 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family GramPos_pilinD1 PF16555.5 CBY31009.1 - 0.014 15.5 2.4 4 7.6 0.9 3.1 2 1 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain DDRGK PF09756.9 CBY31009.1 - 0.33 10.5 32.2 0.57 9.8 32.2 1.4 1 0 0 1 1 1 0 DDRGK domain U79_P34 PF03064.16 CBY31009.1 - 8.4 5.7 19.1 16 4.8 19.1 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ArAE_1 PF06081.11 CBY31010.1 - 0.0098 16.0 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 ACBP PF00887.19 CBY31011.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 1.8 2 1 0 2 2 2 1 Acyl CoA binding protein Sec62 PF03839.16 CBY31011.1 - 0.12 11.9 8.9 0.17 11.4 8.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 CBY31011.1 - 0.5 10.2 10.0 0.62 9.8 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CBY31011.1 - 2.6 6.7 5.4 2.8 6.6 5.4 1.2 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CBY31011.1 - 7.8 4.8 8.8 9.9 4.5 8.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cation_efflux PF01545.21 CBY31012.1 - 9.1e-48 162.6 14.3 1.1e-47 162.3 14.3 1.1 1 0 0 1 1 1 1 Cation efflux family zf-HIT PF04438.16 CBY31013.1 - 7.2e-11 41.8 12.4 1.4e-10 40.8 12.4 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 CBY31013.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.6 CBY31013.1 - 0.044 13.9 6.2 0.04 14.0 3.9 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sigma70_r4_2 PF08281.12 CBY31013.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Sterile PF03015.19 CBY31013.1 - 0.1 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Male sterility protein PolC_DP2 PF03833.13 CBY31013.1 - 0.94 7.2 5.7 1.5 6.6 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.18 CBY31013.1 - 2.2 8.4 14.5 1.3 9.2 12.1 1.9 2 0 0 2 2 2 0 MYND finger EMP24_GP25L PF01105.24 CBY31014.1 - 4.1e-35 121.4 4.6 7.1e-35 120.6 4.6 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5362 PF17319.2 CBY31014.1 - 0.073 12.9 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PBP1_TM PF14812.6 CBY31014.1 - 0.24 11.8 8.3 0.52 10.7 8.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PEHE PF15275.6 CBY31015.1 - 8.3e-12 45.9 1.2 8.3e-12 45.9 1.2 2.7 2 1 0 2 2 2 1 PEHE domain Angiomotin_C PF12240.8 CBY31015.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.7 3 0 0 3 3 3 1 Angiomotin C terminal Rootletin PF15035.6 CBY31015.1 - 0.0029 17.7 0.3 0.0029 17.7 0.3 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CENP-Q PF13094.6 CBY31015.1 - 0.0032 17.7 0.4 0.0032 17.7 0.4 2.5 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.11 CBY31015.1 - 0.0066 16.7 0.4 0.0066 16.7 0.4 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) NAD_binding_6 PF08030.12 CBY31015.1 - 0.15 12.2 0.9 0.58 10.3 0.1 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DivIC PF04977.15 CBY31015.1 - 6.5 6.6 8.4 2.2 8.1 0.9 2.4 2 0 0 2 2 2 0 Septum formation initiator EF-hand_7 PF13499.6 CBY31016.1 - 0.11 13.0 7.5 0.15 12.6 1.8 2.9 2 1 1 3 3 3 0 EF-hand domain pair SNF2_N PF00176.23 CBY31017.1 - 3.8e-17 62.1 0.0 3.9e-17 62.0 0.0 1.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CBY31017.1 - 0.00013 21.8 0.0 0.00019 21.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CBY31017.1 - 0.0028 17.3 0.2 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 CBY31017.1 - 0.0041 17.1 1.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit C_Hendra PF16821.5 CBY31017.1 - 0.0091 15.9 1.5 0.016 15.1 1.5 1.4 1 0 0 1 1 1 1 C protein from hendra and measles viruses TLP-20 PF06088.11 CBY31017.1 - 2.1 8.2 7.4 4.2 7.2 7.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 CBY31017.1 - 5.2 6.7 9.1 7.7 6.2 9.1 1.3 1 0 0 1 1 1 0 FAM176 family Hydrolase PF00702.26 CBY31018.1 - 4.7e-07 30.3 0.0 4.8e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY31018.1 - 0.0029 18.0 0.0 0.0031 18.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY31018.1 - 0.04 13.6 0.0 0.044 13.5 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.6 CBY31018.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain Cation_ATPase_C PF00689.21 CBY31019.1 - 3.3e-43 147.5 1.9 4.1e-43 147.2 1.9 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.12 CBY31019.1 - 0.078 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Sulfotransfer_3 PF13469.6 CBY31020.1 - 1.5e-06 28.8 0.0 0.0032 17.9 0.0 2.3 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY31020.1 - 1.1e-05 25.1 0.0 3.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Peripla_BP_1 PF00532.21 CBY31020.1 - 4.9e-05 22.9 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family IU_nuc_hydro PF01156.19 CBY31020.1 - 0.085 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase UvsY PF11056.8 CBY31021.1 - 0.57 10.5 3.6 0.53 10.6 0.2 2.4 3 0 0 3 3 3 0 Recombination, repair and ssDNA binding protein UvsY ThiF PF00899.21 CBY31023.1 - 1.7e-61 207.7 0.0 2.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CBY31023.1 - 1.1e-14 54.3 0.6 1.9e-14 53.6 0.6 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 CBY31023.1 - 0.0026 18.3 0.3 0.0055 17.3 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain PglD_N PF17836.1 CBY31023.1 - 0.016 15.8 0.1 0.17 12.6 0.1 2.6 2 0 0 2 2 2 0 PglD N-terminal domain Shikimate_DH PF01488.20 CBY31023.1 - 0.094 12.8 0.3 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CDKN3 PF05706.12 CBY31023.1 - 0.13 11.9 0.8 19 4.9 0.0 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_19 PF14559.6 CBY31024.1 - 0.0032 17.9 1.9 0.0049 17.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat SEP PF08059.13 CBY31024.1 - 0.035 14.7 0.3 0.74 10.4 0.0 2.6 3 0 0 3 3 3 0 SEP domain DUF2975 PF11188.8 CBY31026.1 - 8.1 6.3 8.5 0.72 9.7 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Lectin_C PF00059.21 CBY31027.1 - 4.3e-11 43.5 0.9 1e-10 42.3 0.9 1.7 1 0 0 1 1 1 1 Lectin C-type domain Connexin PF00029.19 CBY31028.1 - 2.1e-25 89.9 3.0 2.7e-20 73.1 1.4 2.1 2 0 0 2 2 2 2 Connexin Avian_gp85 PF03708.14 CBY31028.1 - 0.0073 15.5 0.4 0.015 14.5 0.4 1.5 1 0 0 1 1 1 1 Avian retrovirus envelope protein, gp85 Ac76 PF05814.11 CBY31028.1 - 7 6.7 8.1 15 5.7 0.3 2.9 3 0 0 3 3 3 0 Orf76 (Ac76) Trypsin PF00089.26 CBY31029.1 - 3.5e-40 138.2 0.1 3.9e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY31029.1 - 0.00017 22.5 0.0 0.00028 21.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CBY31030.1 - 3.3e-40 138.3 0.2 3.9e-40 138.0 0.2 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY31030.1 - 2.5e-05 25.2 0.0 4.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY31030.1 - 0.0019 18.5 0.0 0.0031 17.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Kinocilin PF15033.6 CBY31031.1 - 0.25 11.0 1.4 0.47 10.1 0.2 1.9 2 0 0 2 2 2 0 Kinocilin protein DUF4140 PF13600.6 CBY31033.1 - 0.0057 17.1 7.9 1.2 9.7 0.5 3.4 3 0 0 3 3 3 2 N-terminal domain of unknown function (DUF4140) SID-1_RNA_chan PF13965.6 CBY31033.1 - 0.071 11.5 4.8 0.88 7.9 1.1 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Ctr PF04145.15 CBY31033.1 - 3.6 8.2 14.2 2.4e+03 -1.0 14.2 2.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF1682 PF07946.14 CBY31033.1 - 4.7 6.3 25.9 0.03 13.6 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) YMF19 PF02326.15 CBY31033.1 - 9.3 7.1 9.9 1.7 9.5 0.4 3.1 2 1 0 2 2 2 0 Plant ATP synthase F0 Glyco_hydro_31 PF01055.26 CBY31035.1 - 1.9e-116 389.9 1.0 2.7e-116 389.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBY31035.1 - 0.0032 17.8 0.1 0.011 16.0 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Trefoil PF00088.18 CBY31035.1 - 0.037 13.9 3.5 0.099 12.5 3.5 1.8 1 0 0 1 1 1 0 Trefoil (P-type) domain NtCtMGAM_N PF16863.5 CBY31035.1 - 0.29 11.4 1.1 3.4 7.9 0.1 2.6 2 1 1 3 3 3 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase ABC_tran PF00005.27 CBY31036.1 - 1.1e-48 165.2 0.0 1.8e-25 90.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CBY31036.1 - 4.3e-23 82.6 0.0 1.3e-06 28.5 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBY31036.1 - 5.6e-08 32.9 0.1 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CBY31036.1 - 6.8e-08 32.2 0.0 0.22 11.0 0.0 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY31036.1 - 3.6e-07 29.8 2.3 0.0014 18.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY31036.1 - 9.5e-07 28.8 5.6 0.0016 18.2 0.3 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBY31036.1 - 4.3e-05 23.9 0.4 0.068 13.6 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY31036.1 - 9e-05 22.8 0.6 0.28 11.5 0.0 3.3 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CBY31036.1 - 0.00013 22.0 0.7 0.28 11.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CBY31036.1 - 0.00046 20.0 0.1 0.92 9.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CBY31036.1 - 0.00052 19.8 0.1 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBY31036.1 - 0.00062 19.8 0.4 0.17 11.9 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CBY31036.1 - 0.00067 19.4 0.3 18 5.0 0.1 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_16 PF13191.6 CBY31036.1 - 0.00088 19.7 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 CBY31036.1 - 0.002 18.5 0.0 3.8 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 CBY31036.1 - 0.0022 18.6 17.0 0.05 14.1 0.8 3.8 4 1 0 4 4 3 2 AAA domain AAA_33 PF13671.6 CBY31036.1 - 0.0033 17.6 0.4 4.2 7.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY31036.1 - 0.0044 17.6 2.3 4.4 7.9 0.0 3.5 5 0 0 5 5 2 1 AAA domain AAA_28 PF13521.6 CBY31036.1 - 0.0052 17.0 1.5 3.5 7.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain MukB PF04310.12 CBY31036.1 - 0.0081 16.0 1.4 0.046 13.5 0.1 2.3 2 0 0 2 2 2 1 MukB N-terminal AAA_27 PF13514.6 CBY31036.1 - 0.0085 15.7 0.3 0.45 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBY31036.1 - 0.019 14.9 2.3 0.5 10.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CBY31036.1 - 0.023 14.8 0.2 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_13 PF13166.6 CBY31036.1 - 0.024 13.3 3.0 1.6 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CBY31036.1 - 0.028 13.8 0.1 7.5 5.9 0.1 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NAD_binding_7 PF13241.6 CBY31036.1 - 0.038 14.4 0.2 0.092 13.2 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AAA_14 PF13173.6 CBY31036.1 - 0.044 13.8 0.4 45 4.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CBY31036.1 - 0.044 14.0 0.2 2.1 8.6 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 CBY31036.1 - 0.051 13.1 1.6 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CBY31036.1 - 0.13 12.2 2.4 9.5 6.1 0.1 3.1 4 0 0 4 4 3 0 Rad17 P-loop domain SRP54 PF00448.22 CBY31036.1 - 0.13 11.8 4.0 6.2 6.4 0.1 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CBY31036.1 - 0.17 12.1 0.0 51 4.2 0.0 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 CBY31036.1 - 0.21 11.5 5.8 16 5.4 0.1 4.5 5 0 0 5 5 5 0 NTPase cobW PF02492.19 CBY31036.1 - 0.31 10.6 2.3 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.8 CBY31036.1 - 0.64 7.5 4.3 0.66 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF87 PF01935.17 CBY31036.1 - 7.7 6.5 7.4 16 5.5 0.3 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain EF-hand_1 PF00036.32 CBY31037.1 - 8.9e-08 31.2 1.6 9.8e-05 21.6 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY31037.1 - 4.1e-06 26.0 3.8 6.1e-05 22.3 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY31037.1 - 6.2e-06 25.7 3.1 0.0031 17.3 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY31037.1 - 0.00015 22.2 1.6 0.0031 17.9 1.6 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY31037.1 - 0.00053 19.8 1.1 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY31038.1 - 5.3e-08 31.9 2.3 7.1e-05 22.1 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY31038.1 - 1e-05 25.9 1.5 0.03 14.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY31038.1 - 0.0003 20.5 7.6 0.0068 16.3 0.7 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY31038.1 - 0.0004 19.8 0.6 0.0004 19.8 0.6 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY31038.1 - 0.0032 17.3 0.4 0.059 13.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair RhoGEF PF00621.20 CBY31039.1 - 8.8e-31 107.6 1.0 1.2e-30 107.1 1.0 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CBY31039.1 - 0.0068 16.9 0.7 0.02 15.4 0.1 2.1 2 0 0 2 2 2 1 PH domain DUF5014 PF16406.5 CBY31040.1 - 0.006 16.8 0.0 0.023 15.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5014) API5 PF05918.11 CBY31041.1 - 0.0003 19.7 5.5 0.0003 19.7 5.5 1.7 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DUF3012 PF11216.8 CBY31041.1 - 0.0019 18.2 0.4 0.0044 17.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) Whib PF02467.16 CBY31044.1 - 3.6 8.3 7.5 2.6 8.7 0.6 3.1 2 1 1 3 3 3 0 Transcription factor WhiB EF-hand_1 PF00036.32 CBY31046.1 - 9.9e-05 21.6 0.6 0.00084 18.7 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY31046.1 - 0.00015 22.1 0.4 0.049 14.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY31046.1 - 0.00028 20.6 0.4 0.0036 17.1 0.1 2.9 4 1 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 CBY31046.1 - 0.00071 19.0 0.2 0.0037 16.7 0.2 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY31046.1 - 0.0083 16.0 0.0 0.065 13.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair bZIP_2 PF07716.15 CBY31050.1 - 7.5e-12 45.2 12.1 7.5e-12 45.2 12.1 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY31050.1 - 0.0019 18.3 9.7 0.0019 18.3 9.7 1.5 1 1 1 2 2 2 1 bZIP transcription factor Fib_alpha PF08702.10 CBY31050.1 - 0.34 11.1 2.7 0.34 11.1 2.7 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tudor-knot PF11717.8 CBY31052.1 - 1.7e-11 43.8 0.5 3.9e-11 42.6 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 CBY31052.1 - 1.9e-09 37.2 1.6 8.2e-08 31.8 0.9 2.4 1 1 0 1 1 1 1 MRG Chromo PF00385.24 CBY31052.1 - 0.018 14.9 4.3 0.018 14.9 4.3 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Phospholip_A2_1 PF00068.19 CBY31053.1 - 1.4e-20 73.8 6.0 3.2e-20 72.7 6.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 zf-C2H2_4 PF13894.6 CBY31054.1 - 0.0088 16.8 3.8 0.02 15.7 3.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY31054.1 - 0.037 13.9 0.2 0.99 9.4 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CBY31054.1 - 0.067 13.5 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CBY31054.1 - 0.11 13.0 4.9 0.17 12.4 3.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4674 PF15719.5 CBY31054.1 - 0.99 9.4 10.0 0.12 12.5 1.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4674) zf-H2C2_5 PF13909.6 CBY31054.1 - 4.6 7.1 8.1 2 8.2 5.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Phospholip_A2_1 PF00068.19 CBY31056.1 - 1.3e-14 54.7 9.1 1.3e-14 54.7 9.1 2.3 2 0 0 2 2 2 1 Phospholipase A2 COesterase PF00135.28 CBY31057.1 - 1.2e-108 364.2 0.5 5.3e-59 200.5 0.4 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY31057.1 - 1.1e-14 54.9 0.4 1.1e-07 31.9 0.1 3.6 2 2 0 2 2 2 2 alpha/beta hydrolase fold EGF_3 PF12947.7 CBY31057.1 - 2.5e-08 34.0 8.2 2.5e-08 34.0 8.2 5.2 4 0 0 4 4 4 1 EGF domain EGF PF00008.27 CBY31057.1 - 0.00068 19.9 8.9 0.00068 19.9 8.9 4.4 4 0 0 4 4 4 2 EGF-like domain cEGF PF12662.7 CBY31057.1 - 0.0088 15.9 2.1 0.0088 15.9 2.1 4.8 5 0 0 5 5 5 1 Complement Clr-like EGF-like Say1_Mug180 PF10340.9 CBY31057.1 - 0.13 11.1 0.1 0.88 8.4 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase BTB_2 PF02214.22 CBY31058.1 - 4.8e-26 90.9 0.0 1.7e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY31058.1 - 6.2e-18 64.9 2.4 5.3e-17 61.9 0.3 2.2 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 CBY31058.1 - 6.5e-13 48.5 1.1 6.5e-13 48.5 1.1 1.9 2 0 0 2 2 2 1 Ion channel ECF_trnsprt PF12822.7 CBY31058.1 - 0.13 12.4 0.8 0.27 11.3 0.1 1.6 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Kelch_5 PF13854.6 CBY31059.1 - 0.0014 18.6 1.0 0.054 13.5 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY31059.1 - 0.55 10.6 5.8 5.1 7.5 0.0 3.5 2 1 1 3 3 3 0 Kelch motif Trypsin PF00089.26 CBY31060.1 - 1.1e-29 103.8 0.0 1.8e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kelch_6 PF13964.6 CBY31060.1 - 0.036 14.4 0.4 4.9 7.6 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Trypsin PF00089.26 CBY31061.1 - 5.5e-11 42.7 0.0 6.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin nos_propeller_2 PF18793.1 CBY31061.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 Trypsin PF00089.26 CBY31062.1 - 1.6e-35 122.9 0.0 2.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kelch_6 PF13964.6 CBY31062.1 - 0.023 15.0 1.9 1.6 9.2 0.0 3.3 3 1 1 4 4 4 0 Kelch motif Big_4 PF07532.11 CBY31062.1 - 0.084 12.6 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) DnaJ PF00226.31 CBY31063.1 - 2.4e-05 24.4 0.1 0.0079 16.3 0.1 2.5 1 1 1 2 2 2 2 DnaJ domain THOC7 PF05615.13 CBY31063.1 - 0.0069 16.7 3.1 0.0079 16.5 3.1 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 Cnn_1N PF07989.11 CBY31063.1 - 0.012 15.8 3.3 0.15 12.3 3.0 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 CBY31063.1 - 0.017 15.4 5.2 0.017 15.4 5.2 1.7 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.15 CBY31063.1 - 0.21 11.4 5.6 0.24 11.2 3.6 1.9 2 0 0 2 2 2 0 Septum formation initiator M PF02370.16 CBY31063.1 - 0.27 11.9 8.8 4.9 8.0 5.2 2.3 2 0 0 2 2 2 0 M protein repeat Trypsin PF00089.26 CBY31064.1 - 5.5e-11 42.7 0.0 6.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin nos_propeller_2 PF18793.1 CBY31064.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat 2 Kelch_6 PF13964.6 CBY31065.1 - 0.15 12.4 1.7 21 5.6 0.0 3.3 2 1 1 3 3 3 0 Kelch motif Collagen PF01391.18 CBY31066.1 - 0.039 13.7 5.3 0.059 13.1 5.3 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Kelch_2 PF07646.15 CBY31067.1 - 0.058 13.4 0.1 7.1 6.8 0.0 2.9 2 0 0 2 2 2 0 Kelch motif ShK PF01549.24 CBY31068.1 - 0.00047 20.6 42.8 0.016 15.7 7.5 4.6 4 0 0 4 4 4 4 ShK domain-like TPR_12 PF13424.6 CBY31070.1 - 4e-60 200.1 28.8 2e-17 63.3 2.7 5.1 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 CBY31070.1 - 2.1e-53 176.8 17.0 3.6e-13 48.9 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBY31070.1 - 1.1e-27 94.0 14.3 2.5e-05 24.0 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 CBY31070.1 - 4.7e-20 70.5 26.9 9.4e-06 25.2 0.3 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31070.1 - 5.5e-15 54.2 26.3 0.0051 16.8 0.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY31070.1 - 4.3e-12 45.2 21.1 0.00069 19.6 0.9 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY31070.1 - 1.3e-08 35.2 13.3 1.9e-05 25.1 0.5 5.1 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY31070.1 - 3.3e-08 34.0 14.6 0.02 15.5 0.5 5.7 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY31070.1 - 1.2e-07 31.5 4.8 1.2e-07 31.5 4.8 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 CBY31070.1 - 8.8e-07 28.9 7.5 0.25 11.8 0.2 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY31070.1 - 3.6e-05 23.9 5.6 0.15 12.3 0.1 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CBY31070.1 - 4.5e-05 23.4 2.0 0.024 14.9 0.0 4.8 6 0 0 6 6 4 1 PPR repeat TPR_14 PF13428.6 CBY31070.1 - 8.6e-05 23.0 23.6 1 10.3 0.1 6.8 5 1 3 8 8 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CBY31070.1 - 0.0016 18.9 0.0 46 5.1 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 CBY31070.1 - 0.02 15.0 0.8 0.99 9.6 0.1 3.3 3 0 0 3 3 3 0 PPR repeat family L27 PF02828.16 CBY31070.1 - 0.047 13.4 0.5 1.9 8.3 0.0 3.0 2 0 0 2 2 2 0 L27 domain DUF1897 PF09005.10 CBY31070.1 - 0.1 12.1 6.2 2.9 7.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) GHL5 PF14872.6 CBY31070.1 - 0.11 10.5 0.5 0.17 9.9 0.1 1.4 2 0 0 2 2 2 0 Hypothetical glycoside hydrolase 5 RPN6_N PF18055.1 CBY31070.1 - 0.23 11.8 7.1 2.7 8.4 0.2 4.3 3 2 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain RPN7 PF10602.9 CBY31070.1 - 1.1 9.0 10.1 0.3 10.8 1.6 3.5 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TMF_TATA_bd PF12325.8 CBY31070.1 - 1.3 9.3 10.4 0.13 12.5 2.1 3.0 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_6 PF13174.6 CBY31070.1 - 2.1 9.2 16.5 1.8 9.4 0.6 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat I-set PF07679.16 CBY31072.1 - 2e-16 59.8 0.0 4e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY31072.1 - 1.3e-15 57.7 0.0 6.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY31072.1 - 6.3e-12 45.4 0.1 5.4e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY31072.1 - 9.4e-12 45.1 0.0 8.4e-08 32.4 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 CBY31072.1 - 1.3e-09 38.1 0.0 0.00072 19.7 0.0 2.7 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY31072.1 - 2.3e-09 37.4 0.0 0.00015 22.1 0.0 2.2 2 0 0 2 2 2 2 Immunoglobulin domain C1-set PF07654.15 CBY31072.1 - 0.018 15.4 0.0 0.72 10.3 0.0 2.6 3 0 0 3 3 3 0 Immunoglobulin C1-set domain TPR_1 PF00515.28 CBY31077.1 - 9.1e-14 50.6 1.3 0.00045 19.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31077.1 - 3.3e-13 48.6 3.4 0.00051 19.9 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY31077.1 - 4.9e-10 39.8 1.3 5.9e-06 26.7 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY31077.1 - 6.8e-08 33.0 1.5 0.00014 22.5 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY31077.1 - 1.2e-07 31.9 0.7 0.022 15.6 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY31077.1 - 7.1e-07 29.0 3.1 0.46 10.8 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY31077.1 - 1.4e-06 27.9 1.1 0.0021 17.7 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY31077.1 - 5.8e-05 23.3 1.1 1.5 9.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY31077.1 - 0.00012 22.2 0.7 0.00025 21.2 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY31077.1 - 0.00025 21.2 0.4 1.7 9.2 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY31077.1 - 0.00065 20.2 4.3 1.2 9.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY31077.1 - 0.0046 17.1 1.9 0.013 15.6 1.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY31077.1 - 0.0064 16.3 1.5 17 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBY31077.1 - 0.011 16.1 0.1 0.52 10.8 0.2 2.5 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation BTAD PF03704.17 CBY31077.1 - 0.016 15.7 0.9 0.44 11.0 1.5 2.6 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Arnt_C PF18583.1 CBY31077.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Galactosyl_T PF01762.21 CBY31078.1 - 3.6e-15 56.3 0.1 2.6e-14 53.5 0.1 2.1 1 1 0 1 1 1 1 Galactosyltransferase DNA_pol_A_exo1 PF01612.20 CBY31081.1 - 9.5e-15 54.7 0.0 2.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PetG PF02529.15 CBY31081.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Ldl_recept_b PF00058.17 CBY31082.1 - 1.5e-20 73.4 14.2 0.00015 22.2 0.0 10.0 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.16 CBY31082.1 - 3.5e-13 49.7 6.9 2.9e-11 43.6 0.0 4.3 4 1 0 4 4 3 2 HYR domain Ephrin_rec_like PF07699.13 CBY31082.1 - 9.9e-08 31.6 2.4 9.9e-08 31.6 2.4 2.7 1 1 1 2 2 2 1 Putative ephrin-receptor like FXa_inhibition PF14670.6 CBY31082.1 - 2e-07 31.2 55.1 3.8e-05 23.9 8.7 5.7 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site SGL PF08450.12 CBY31082.1 - 3.1e-05 23.7 2.2 0.72 9.4 0.2 5.6 4 2 1 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region fn1 PF00039.18 CBY31082.1 - 0.00014 22.0 5.8 0.00035 20.7 5.8 1.7 1 0 0 1 1 1 1 Fibronectin type I domain FAM176 PF14851.6 CBY31082.1 - 0.00048 19.8 0.7 0.00048 19.8 0.7 2.3 1 1 1 2 2 1 1 FAM176 family Arylesterase PF01731.20 CBY31082.1 - 0.00072 19.7 0.0 18 5.6 0.0 5.9 7 1 0 7 7 6 0 Arylesterase EphA2_TM PF14575.6 CBY31082.1 - 0.002 19.0 0.1 0.0047 17.8 0.1 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBY31082.1 - 0.14 12.4 0.3 0.39 10.9 0.4 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4381) FAM76 PF16046.5 CBY31082.1 - 0.22 10.9 6.5 0.5 9.7 6.5 1.6 1 0 0 1 1 1 0 FAM76 protein Neur_chan_memb PF02932.16 CBY31082.1 - 0.28 11.2 1.4 0.62 10.1 1.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EGF PF00008.27 CBY31082.1 - 1.1 9.6 37.8 0.47 10.8 8.7 4.8 4 0 0 4 4 4 0 EGF-like domain TMEM51 PF15345.6 CBY31082.1 - 1.6 8.5 8.3 0.14 12.0 1.1 2.2 1 1 0 2 2 2 0 Transmembrane protein 51 FctA PF12892.7 CBY31082.1 - 2 9.2 12.3 5.2 7.9 12.3 1.7 1 0 0 1 1 1 0 Spy0128-like isopeptide containing domain Lectin_C PF00059.21 CBY31083.1 - 6.5e-14 52.6 2.5 1.8e-12 47.9 0.2 2.5 2 0 0 2 2 2 2 Lectin C-type domain Trefoil PF00088.18 CBY31083.1 - 0.056 13.3 5.0 0.16 11.8 5.0 1.8 1 0 0 1 1 1 0 Trefoil (P-type) domain Kelch_2 PF07646.15 CBY31084.1 - 0.0028 17.6 2.4 1.9 8.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Sulfotransfer_1 PF00685.27 CBY31085.1 - 5.5e-14 52.3 0.1 8.7e-13 48.4 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31085.1 - 1.9e-10 41.5 0.0 1.4e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family DUF3504 PF12012.8 CBY31085.1 - 0.1 12.5 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Cadherin_C_2 PF16492.5 CBY31086.1 - 0.075 13.8 0.0 0.2 12.5 0.0 1.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal DUF3671 PF12420.8 CBY31086.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF4229 PF14012.6 CBY31087.1 - 0.0012 18.9 0.9 0.0018 18.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) Phage_holin_3_6 PF07332.11 CBY31087.1 - 0.023 14.8 0.6 0.029 14.4 0.6 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 CBY31087.1 - 0.053 12.3 0.9 0.05 12.4 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC12 PF06645.13 CBY31087.1 - 0.18 11.9 2.1 0.21 11.7 1.4 1.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) LapA_dom PF06305.11 CBY31087.1 - 0.25 11.2 3.8 0.49 10.2 3.8 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF202 PF02656.15 CBY31087.1 - 1.6 9.2 5.5 4 8.0 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Amidohydro_3 PF07969.11 CBY31088.1 - 4.5e-17 62.7 0.6 2.7e-10 40.3 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 CBY31088.1 - 2.8e-12 46.6 3.3 1.8e-10 40.6 3.3 2.3 1 1 0 1 1 1 1 Amidohydrolase family DSPn PF14671.6 CBY31089.1 - 2.9e-61 206.1 0.1 4.1e-61 205.5 0.1 1.2 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half MAP7 PF05672.11 CBY31090.1 - 1.4e-10 41.1 55.6 1.4e-10 41.1 55.6 3.2 3 1 1 4 4 4 1 MAP7 (E-MAP-115) family Membralin PF09746.9 CBY31091.1 - 7.1e-64 216.2 6.3 3.3e-51 174.5 2.8 2.7 1 1 0 2 2 2 2 Tumour-associated protein RsgA_GTPase PF03193.16 CBY31092.1 - 0.00027 20.9 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase GBP PF02263.19 CBY31092.1 - 0.0047 16.2 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 CBY31092.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY31092.1 - 0.06 13.7 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Smg8_Smg9 PF10220.9 CBY31092.1 - 0.076 11.3 0.1 0.22 9.8 0.1 1.6 1 1 0 1 1 1 0 Smg8_Smg9 ABC_tran PF00005.27 CBY31092.1 - 0.17 12.4 0.1 0.33 11.5 0.0 1.5 2 0 0 2 2 2 0 ABC transporter SCAMP PF04144.13 CBY31093.1 - 1.2e-62 211.3 13.8 1.4e-62 211.1 13.8 1.1 1 0 0 1 1 1 1 SCAMP family FERM_F1 PF18379.1 CBY31093.1 - 0.37 10.8 3.1 0.95 9.5 3.1 1.6 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain Pedibin PF08182.11 CBY31093.1 - 0.51 10.2 5.5 0.9 9.4 5.5 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family Pkinase PF00069.25 CBY31094.1 - 2.4e-64 217.2 0.0 3.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31094.1 - 3.1e-32 111.9 0.0 4.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PB1 PF00564.24 CBY31094.1 - 1.3e-12 47.5 0.1 3e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Kinase-like PF14531.6 CBY31094.1 - 2.1e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY31094.1 - 0.017 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CBY31094.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY31094.1 - 0.027 14.1 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CBY31094.1 - 0.036 14.8 1.5 0.036 14.8 1.5 2.3 3 0 0 3 3 3 0 Protein kinase C terminal domain APH PF01636.23 CBY31094.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family CaiF_GrlA PF07180.11 CBY31094.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator DUF3774 PF12609.8 CBY31095.1 - 0.16 13.0 0.6 0.16 13.0 0.6 1.1 1 0 0 1 1 1 0 Wound-induced protein Peptidase_C1 PF00112.23 CBY31096.1 - 2.1e-72 243.7 0.4 2.9e-72 243.3 0.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY31096.1 - 2.9e-10 40.4 3.9 2.9e-10 40.4 3.9 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY31096.1 - 7.2e-06 25.0 1.3 0.033 13.0 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family OST-HTH PF12872.7 CBY31096.1 - 0.081 12.8 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 OST-HTH/LOTUS domain IBD PF10416.9 CBY31096.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.8 3 0 0 3 3 3 0 Transcription-initiator DNA-binding domain IBD Acetyltransf_1 PF00583.25 CBY31097.1 - 5.6e-08 33.0 0.1 1.3e-07 31.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY31097.1 - 2.4e-07 30.7 0.4 6.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY31097.1 - 0.00029 20.9 0.0 0.045 13.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY31097.1 - 0.0003 20.8 0.1 0.00071 19.7 0.1 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RecX PF02631.16 CBY31097.1 - 0.00037 21.0 0.2 0.081 13.4 0.0 2.2 2 0 0 2 2 2 1 RecX family Acetyltransf_3 PF13302.7 CBY31097.1 - 0.00048 20.8 0.1 0.0083 16.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY31097.1 - 0.0019 18.6 0.0 0.004 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY31097.1 - 0.084 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ins_allergen_rp PF06757.13 CBY31097.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Pkinase PF00069.25 CBY31098.1 - 1.9e-42 145.5 0.1 1.9e-42 145.5 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31098.1 - 1.7e-29 102.9 1.5 2.3e-29 102.4 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY31098.1 - 1.4e-12 47.5 1.6 2e-12 47.0 0.0 2.0 2 1 0 2 2 2 1 Kinase-like TPR_MLP1_2 PF07926.12 CBY31098.1 - 0.01 15.9 9.8 0.021 14.9 9.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APH PF01636.23 CBY31098.1 - 0.019 14.9 0.1 0.21 11.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CBY31098.1 - 0.022 14.1 0.8 0.085 12.2 0.0 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ly49 PF08391.10 CBY31098.1 - 0.51 10.7 8.1 1.4 9.3 8.1 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pkinase PF00069.25 CBY31099.1 - 3.1e-44 151.3 0.2 3.1e-44 151.3 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31099.1 - 4.3e-30 104.9 0.2 7.3e-30 104.1 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY31099.1 - 3.8e-13 49.4 0.0 1.2e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY31099.1 - 0.00041 19.8 0.8 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rootletin PF15035.6 CBY31099.1 - 0.0016 18.5 9.4 0.0067 16.5 9.3 2.0 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Pkinase_fungal PF17667.1 CBY31099.1 - 0.0041 15.9 0.0 0.0041 15.9 0.0 2.2 2 1 1 3 3 3 1 Fungal protein kinase Yuri_gagarin PF15934.5 CBY31099.1 - 0.0073 16.2 6.5 0.017 15.0 6.5 1.6 1 0 0 1 1 1 1 Yuri gagarin Atg14 PF10186.9 CBY31099.1 - 0.014 14.5 10.9 0.022 13.8 10.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 CBY31099.1 - 0.025 13.1 7.0 0.036 12.6 7.0 1.2 1 0 0 1 1 1 0 Macoilin family Baculo_PEP_C PF04513.12 CBY31099.1 - 0.038 14.0 4.3 0.072 13.1 4.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APH PF01636.23 CBY31099.1 - 0.045 13.7 0.0 0.38 10.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ADIP PF11559.8 CBY31099.1 - 0.12 12.4 12.1 0.11 12.5 10.4 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding T6SS-SciN PF12790.7 CBY31099.1 - 0.32 10.7 2.9 16 5.2 0.7 3.0 3 0 0 3 3 3 0 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 Exonuc_VII_L PF02601.15 CBY31099.1 - 0.96 9.0 6.9 1.7 8.1 6.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBY31099.1 - 1.4 9.0 12.0 0.63 10.1 1.8 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 CBY31099.1 - 3.2 8.0 20.9 0.086 13.0 9.6 2.9 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 CBY31099.1 - 5.1 7.5 13.9 10 6.5 12.9 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 CBY31099.1 - 6.1 6.9 8.9 10 6.2 7.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CBY31099.1 - 7.4 5.8 10.2 31 3.8 10.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 CBY31099.1 - 10 6.9 12.7 6.9 7.4 7.9 2.6 1 1 1 2 2 2 0 Initiation control protein YabA TF_AP-2 PF03299.14 CBY31100.1 - 2.4e-84 282.2 0.0 5.1e-84 281.2 0.0 1.6 1 0 0 1 1 1 1 Transcription factor AP-2 DUF5320 PF17253.2 CBY31101.1 - 0.029 15.4 0.0 0.054 14.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CSN8_PSD8_EIF3K PF10075.9 CBY31102.1 - 6.1e-33 113.8 1.0 1.1e-32 113.1 1.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Reprolysin PF01421.19 CBY31103.1 - 1.8e-30 106.4 0.1 1.8e-30 106.4 0.1 2.4 3 0 0 3 3 2 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR PF08516.12 CBY31103.1 - 1.3e-17 64.3 13.0 1.3e-17 64.3 13.0 4.3 4 1 0 4 4 2 1 ADAM cysteine-rich Disintegrin PF00200.23 CBY31103.1 - 2e-15 57.3 29.6 2e-15 57.3 29.6 4.9 6 1 0 6 6 4 1 Disintegrin Reprolysin_5 PF13688.6 CBY31103.1 - 1.4e-13 51.5 0.0 3.9e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY31103.1 - 4.2e-13 49.9 0.1 8.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY31103.1 - 1.5e-07 31.6 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY31103.1 - 2.3e-06 27.4 0.1 4.6e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBY31103.1 - 0.00047 20.0 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.13 CBY31103.1 - 0.01 15.8 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A EGF_2 PF07974.13 CBY31103.1 - 0.017 15.5 15.8 0.017 15.5 15.8 5.2 4 1 0 4 4 3 0 EGF-like domain Peptidase_M66 PF10462.9 CBY31103.1 - 0.043 12.8 0.1 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase M66 DUF3810 PF12725.7 CBY31103.1 - 0.077 12.3 0.1 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LKAAEAR PF15478.6 CBY31104.1 - 1.4e-10 41.6 8.5 1.7e-10 41.3 8.5 1.2 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif TbpB_B_D PF01298.18 CBY31104.1 - 0.11 12.9 0.5 0.11 12.8 0.5 1.2 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B DUF1974 PF09317.11 CBY31104.1 - 0.4 10.2 5.3 0.45 10.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) PIG-P PF08510.12 CBY31105.1 - 5.7e-21 74.7 5.6 6.5e-21 74.5 5.6 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CBY31105.1 - 0.0013 19.0 8.7 0.0017 18.6 8.7 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pox_A21 PF05323.12 CBY31105.1 - 0.17 12.5 1.6 0.29 11.7 1.6 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Viral_Beta_CD PF04530.12 CBY31105.1 - 0.64 10.3 2.5 0.43 10.9 1.3 1.4 1 1 0 1 1 1 0 Viral Beta C/D like family LSM PF01423.22 CBY31107.1 - 5.1e-16 58.1 0.0 7.3e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 CBY31107.1 - 0.00097 19.8 11.5 0.0015 19.2 11.5 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.6 CBY31107.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain SH2 PF00017.24 CBY31108.1 - 0.0065 16.5 0.1 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 SH2 domain ATG16 PF08614.11 CBY31108.1 - 3.3 7.9 4.7 1.9 8.6 2.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Plk4_PB1 PF18190.1 CBY31109.1 - 0.19 11.9 1.4 0.29 11.3 0.2 1.8 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 1 XTBD PF11952.8 CBY31110.1 - 1.8e-17 62.8 0.0 2.4e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 XRN-Two Binding Domain, XTBD LcrG PF07216.12 CBY31110.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 LcrG protein Pterin_4a PF01329.19 CBY31113.1 - 7.7e-28 96.5 0.0 9e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Spectrin PF00435.21 CBY31114.1 - 0.00081 19.8 10.2 0.00081 19.8 10.2 2.3 1 1 1 2 2 2 1 Spectrin repeat Atg14 PF10186.9 CBY31114.1 - 0.088 11.9 13.4 0.14 11.2 13.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myb_DNA-bind_3 PF12776.7 CBY31114.1 - 0.15 13.1 4.4 0.25 12.3 3.1 1.9 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FapA PF03961.13 CBY31114.1 - 0.16 10.6 12.5 0.21 10.2 12.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sas10_Utp3 PF04000.15 CBY31114.1 - 0.26 11.9 0.3 0.26 11.9 0.3 3.0 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Exonuc_VII_L PF02601.15 CBY31114.1 - 0.43 10.1 7.8 0.53 9.8 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 CBY31114.1 - 0.99 9.8 12.1 0.47 10.9 2.3 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) NTNH_C PF08470.10 CBY31114.1 - 1.1 9.1 4.9 1.3 8.8 1.6 2.3 1 1 2 3 3 3 0 Nontoxic nonhaemagglutinin C-terminal MCC-bdg_PDZ PF10506.9 CBY31114.1 - 2.2 8.4 11.5 25 5.0 5.7 4.0 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Jnk-SapK_ap_N PF09744.9 CBY31114.1 - 2.6 8.2 25.8 0.61 10.3 2.8 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 CBY31114.1 - 3.1 6.2 4.7 2.5 6.5 3.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Ead_Ea22 PF13935.6 CBY31114.1 - 3.9 8.1 16.7 2e+02 2.6 16.7 2.3 1 1 0 1 1 1 0 Ead/Ea22-like protein UPF0242 PF06785.11 CBY31114.1 - 4.5 7.3 22.8 1.1 9.4 18.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CBY31114.1 - 6.8 4.5 9.4 7.5 4.3 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PH_TFIIH PF08567.11 CBY31115.1 - 0.12 12.7 0.3 0.79 10.1 0.0 2.6 2 1 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain RBD-FIP PF09457.10 CBY31115.1 - 0.21 11.5 2.3 0.26 11.2 0.6 2.1 2 0 0 2 2 2 0 FIP domain Tipalpha PF16753.5 CBY31116.1 - 0.069 13.0 0.3 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Rubis-subs-bind PF09273.11 CBY31117.1 - 0.0047 17.6 0.1 0.011 16.4 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding RNA_pol_I_A49 PF06870.12 CBY31118.1 - 0.1 11.4 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor SpoU_methylase PF00588.19 CBY31119.1 - 5.4e-08 33.1 0.0 1.4e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family Ank_4 PF13637.6 CBY31120.1 - 4.9e-11 42.9 0.7 8.6e-10 39.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY31120.1 - 8.9e-09 35.8 0.1 1.6e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY31120.1 - 3.5e-07 30.0 0.3 0.0064 16.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY31120.1 - 0.0008 19.7 2.0 0.0066 16.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY31120.1 - 0.014 15.8 3.0 2.3 8.8 0.4 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF4507 PF14964.6 CBY31121.1 - 7.3e-14 51.5 0.4 2e-13 50.0 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4507) Aim21 PF11489.8 CBY31121.1 - 0.21 10.4 0.8 0.28 10.0 0.8 1.0 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 WD40 PF00400.32 CBY31122.1 - 3.7e-05 24.4 0.9 0.67 10.9 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Tubulin-binding PF00418.19 CBY31122.1 - 0.15 12.1 0.4 0.36 10.9 0.4 1.7 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat BTB_2 PF02214.22 CBY31124.1 - 2.2e-19 69.6 0.3 2.2e-19 69.6 0.3 2.4 2 1 0 2 2 2 1 BTB/POZ domain Ion_trans PF00520.31 CBY31124.1 - 2.8e-16 59.5 15.4 1.8e-15 56.9 15.4 1.9 1 1 0 1 1 1 1 Ion transport protein TetR_C_19 PF17924.1 CBY31124.1 - 0.064 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ERGIC_N PF13850.6 CBY31124.1 - 0.067 13.5 2.1 0.36 11.2 0.0 2.7 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ion_trans_2 PF07885.16 CBY31124.1 - 0.079 12.9 8.3 0.066 13.2 5.1 2.3 2 0 0 2 2 2 0 Ion channel DUF2785 PF10978.8 CBY31126.1 - 0.05 13.4 2.6 0.14 11.9 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Pyridoxal_deC PF00282.19 CBY31127.1 - 2e-97 326.3 0.0 2.3e-97 326.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBY31127.1 - 6.3e-06 25.4 0.1 9.2e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY31127.1 - 2e-05 24.0 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CBY31127.1 - 0.019 13.7 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OKR_DC_1 PF01276.20 CBY31127.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 CBY31127.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II TFIIA PF03153.13 CBY31129.1 - 0.0068 16.5 12.0 0.011 15.8 12.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PDGF_N PF04692.13 CBY31129.1 - 6.5 7.6 7.5 1.2 10.0 2.3 2.5 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Peptidase_C28 PF05408.11 CBY31130.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase MitoNEET_N PF10660.9 CBY31132.1 - 0.095 12.7 0.1 0.095 12.7 0.1 1.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Clc-like PF07062.12 CBY31134.1 - 0.57 9.6 12.8 2.8e+02 0.8 12.8 2.3 1 1 0 1 1 1 0 Clc-like SUR7 PF06687.12 CBY31134.1 - 3 7.4 21.3 3.6 7.2 17.8 2.8 2 1 0 2 2 2 0 SUR7/PalI family G8 PF10162.9 CBY31135.1 - 1.2e-51 173.9 0.0 1.4e-26 92.9 0.0 2.8 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY31135.1 - 8.6e-44 147.5 49.5 3.1e-14 52.8 0.1 10.8 12 0 0 12 12 12 6 IPT/TIG domain EGF_CA PF07645.15 CBY31135.1 - 9.6e-29 99.3 106.4 5.6e-06 26.5 10.8 7.5 7 0 0 7 7 7 6 Calcium-binding EGF domain EGF_3 PF12947.7 CBY31135.1 - 6.5e-13 48.6 92.0 2.6e-08 33.9 11.2 7.9 7 0 0 7 7 7 4 EGF domain cEGF PF12662.7 CBY31135.1 - 3.6e-11 42.8 50.8 0.00011 22.0 2.3 7.3 7 0 0 7 7 7 4 Complement Clr-like EGF-like Beta_helix PF13229.6 CBY31135.1 - 2.5e-08 33.9 29.3 8.7e-05 22.4 3.7 5.5 5 0 0 5 5 5 2 Right handed beta helix region FXa_inhibition PF14670.6 CBY31135.1 - 0.0042 17.3 5.3 0.0042 17.3 5.3 7.5 6 1 1 7 7 7 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY31135.1 - 0.19 12.1 83.4 0.0077 16.5 6.6 7.7 7 0 0 7 7 7 0 EGF-like domain Rrp44_CSD1 PF17216.3 CBY31136.1 - 1.7 8.3 4.6 5.8 6.6 0.0 3.5 4 0 0 4 4 4 0 Rrp44-like cold shock domain EGF_CA PF07645.15 CBY31138.1 - 4 7.7 7.8 4.4 7.6 5.5 2.3 2 1 0 2 2 2 0 Calcium-binding EGF domain LrgA PF03788.14 CBY31139.1 - 0.017 15.1 1.1 0.048 13.6 1.1 1.7 1 0 0 1 1 1 0 LrgA family DUF3487 PF11990.8 CBY31139.1 - 0.078 12.9 3.5 0.78 9.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) RVT_1 PF00078.27 CBY31140.1 - 1.2e-29 103.5 0.0 2.8e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY31140.1 - 0.00046 20.0 0.3 0.008 16.0 0.1 2.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase HTH_32 PF13565.6 CBY31141.1 - 0.025 15.2 0.3 0.034 14.8 0.3 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Med4 PF10018.9 CBY31142.1 - 0.0043 16.8 9.8 0.06 13.0 0.2 2.7 2 0 0 2 2 2 2 Vitamin-D-receptor interacting Mediator subunit 4 Arylsulfotrans PF05935.11 CBY31142.1 - 0.015 14.2 1.0 0.06 12.2 0.1 2.0 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) DUF4407 PF14362.6 CBY31142.1 - 0.059 12.7 15.3 1.1 8.5 12.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CBY31142.1 - 0.14 12.3 25.1 2.3 8.5 0.2 4.0 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 CBY31142.1 - 0.26 11.4 24.2 1.6 8.8 2.5 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 CBY31142.1 - 0.41 11.0 24.3 0.97 9.8 0.0 4.5 4 1 0 4 4 4 0 Csm1 N-terminal domain SlyX PF04102.12 CBY31142.1 - 1 10.1 16.7 0.91 10.2 2.3 3.8 3 2 0 3 3 3 0 SlyX DUF4200 PF13863.6 CBY31142.1 - 1 9.8 27.4 0.34 11.3 10.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 CBY31142.1 - 1.3 9.2 27.8 0.91 9.7 11.9 3.2 3 0 0 3 3 3 0 Tropomyosin like ADIP PF11559.8 CBY31142.1 - 3.3 7.8 28.7 0.099 12.7 9.5 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding CtIP_N PF10482.9 CBY31142.1 - 5 7.2 20.5 0.9 9.6 0.4 3.6 3 2 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain CREPT PF16566.5 CBY31142.1 - 5.4 7.2 19.9 0.097 12.8 7.6 3.0 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DASH_Dam1 PF08653.10 CBY31142.1 - 7.9 6.4 12.3 5 7.0 2.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 GAS PF13851.6 CBY31142.1 - 9.5 5.5 30.7 1.1 8.5 11.1 3.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 CBY31142.1 - 9.9 6.0 25.2 0.72 9.7 2.1 3.7 3 2 1 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 CBY31143.1 - 0.016 15.3 12.0 0.016 15.3 12.0 4.1 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 CBY31143.1 - 0.027 14.5 3.0 0.027 14.5 3.0 5.7 5 1 0 5 5 5 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 CBY31143.1 - 0.029 14.5 2.0 0.029 14.5 2.0 8.5 8 2 3 11 11 11 0 bZIP transcription factor NPV_P10 PF05531.12 CBY31143.1 - 0.26 11.8 18.7 1.6 9.2 0.0 5.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4248 PF14053.6 CBY31143.1 - 1.8 8.7 4.1 22 5.2 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) Phospholip_A2_1 PF00068.19 CBY31144.1 - 1e-17 64.6 12.4 1e-17 64.6 12.4 2.2 1 1 1 2 2 2 1 Phospholipase A2 EphA2_TM PF14575.6 CBY31146.1 - 0.097 13.6 0.0 0.22 12.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 CBY31147.1 - 2.8e-65 220.3 0.0 4.4e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31147.1 - 2.2e-32 112.4 0.2 4.4e-32 111.4 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY31147.1 - 0.00011 21.6 1.1 0.0008 18.8 0.2 2.2 1 1 1 2 2 2 1 Kinase-like 4PPT_N PF17837.1 CBY31147.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Lsr2 PF11774.8 CBY31147.1 - 0.25 11.5 3.7 0.66 10.1 3.7 1.7 1 0 0 1 1 1 0 Lsr2 ICA69 PF04629.14 CBY31147.1 - 8.2 6.7 16.0 3.1 8.0 12.8 1.8 2 1 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain EF-hand_1 PF00036.32 CBY31148.1 - 2.2e-20 70.6 3.3 1.5e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY31148.1 - 9.8e-19 67.6 2.1 2.6e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY31148.1 - 1.1e-14 53.0 2.2 4.3e-06 26.2 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY31148.1 - 3.7e-13 49.1 2.5 5.8e-07 29.3 0.1 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31148.1 - 5e-11 41.6 3.9 0.00075 18.9 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CBY31148.1 - 4.5e-05 23.3 0.4 0.22 11.5 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBY31148.1 - 0.00016 21.8 0.5 0.056 13.6 0.0 2.8 2 1 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 CBY31148.1 - 0.00017 22.4 0.0 0.00038 21.3 0.0 1.5 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY31148.1 - 0.004 17.4 0.0 0.42 11.0 0.0 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 CBY31148.1 - 0.14 10.7 0.0 1.1 7.7 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) zf_Hakai PF18408.1 CBY31149.1 - 5.6e-06 25.9 1.1 1.6e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain zf-H2C2_5 PF13909.6 CBY31149.1 - 0.00011 21.9 9.6 0.095 12.5 0.0 5.1 5 0 0 5 5 5 2 C2H2-type zinc-finger domain AKAP95 PF04988.12 CBY31149.1 - 0.00033 20.9 15.8 0.092 13.0 4.6 3.8 3 1 0 3 3 3 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 CBY31149.1 - 0.00088 19.9 21.4 0.35 11.8 0.1 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf_ZIC PF18366.1 CBY31149.1 - 0.004 17.2 1.8 0.02 15.0 0.1 2.4 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_12 PF18658.1 CBY31149.1 - 0.014 15.0 3.3 0.13 11.9 0.1 3.1 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 CBY31149.1 - 2 8.1 7.3 4.5 7.0 0.1 3.1 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CBY31149.1 - 6.6 7.1 12.6 2.8 8.3 0.3 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RGS PF00615.19 CBY31150.1 - 4.1e-17 62.5 7.6 3.9e-09 36.8 0.9 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain ARL2_Bind_BART PF11527.8 CBY31150.1 - 0.0045 17.1 0.8 0.15 12.2 0.0 3.2 2 1 1 3 3 3 1 The ARF-like 2 binding protein BART 4HB_MCP_1 PF12729.7 CBY31150.1 - 0.022 14.3 1.3 0.04 13.5 1.3 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Daxx PF03344.15 CBY31150.1 - 0.14 12.3 1.3 5.4 7.1 0.0 3.3 4 0 0 4 4 4 0 Daxx N-terminal Rassf1C-interacting domain MAP65_ASE1 PF03999.12 CBY31151.1 - 3.2e-64 217.7 40.6 6.6e-64 216.7 40.3 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ECH_2 PF16113.5 CBY31151.1 - 1.5 8.3 4.7 0.39 10.2 0.6 2.1 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase DUF4279 PF14106.6 CBY31151.1 - 2.8 8.2 8.2 2.1 8.6 0.2 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4279) DAD PF02109.16 CBY31152.1 - 1.8e-43 147.2 2.8 2.2e-43 147.0 2.8 1.1 1 0 0 1 1 1 1 DAD family YIF1 PF03878.15 CBY31152.1 - 0.0005 19.7 0.3 0.00054 19.6 0.3 1.1 1 0 0 1 1 1 1 YIF1 NuA4 PF09340.10 CBY31153.1 - 3.4e-20 71.7 0.9 4.5e-20 71.3 0.9 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HRM PF02793.22 CBY31154.1 - 0.0033 17.7 0.4 0.0061 16.8 0.4 1.4 1 0 0 1 1 1 1 Hormone receptor domain SCIMP PF15050.6 CBY31154.1 - 0.0055 17.2 0.0 0.0073 16.8 0.0 1.1 1 0 0 1 1 1 1 SCIMP protein LRR19-TM PF15176.6 CBY31154.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SieB PF14163.6 CBY31154.1 - 0.044 13.3 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Super-infection exclusion protein B Amnionless PF14828.6 CBY31154.1 - 0.053 12.4 0.0 0.057 12.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless Vpu PF00558.19 CBY31154.1 - 0.062 13.1 0.3 0.085 12.6 0.3 1.2 1 0 0 1 1 1 0 Vpu protein Orthoreo_P10 PF07204.11 CBY31154.1 - 0.073 13.0 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 WBP-1 PF11669.8 CBY31154.1 - 0.076 13.7 0.2 0.094 13.4 0.1 1.3 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF3169 PF11368.8 CBY31154.1 - 0.083 12.4 0.4 0.1 12.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) LYRIC PF15686.5 CBY31154.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 1 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Conotoxin PF02950.17 CBY31154.1 - 0.12 13.4 0.4 0.44 11.6 0.0 1.9 2 0 0 2 2 2 0 Conotoxin FMN_bind PF04205.14 CBY31155.1 - 0.099 13.2 0.1 3.2 8.4 0.0 2.2 1 1 1 2 2 2 0 FMN-binding domain NPM1-C PF16276.5 CBY31156.1 - 9.4e-06 25.5 2.3 0.0019 18.1 0.1 2.4 2 0 0 2 2 2 2 Nucleophosmin C-terminal domain DUF3884 PF13024.6 CBY31156.1 - 0.012 15.1 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) RNase_T PF00929.24 CBY31157.1 - 2.3e-10 41.2 0.1 5.8e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBY31157.1 - 0.00027 20.7 0.2 0.0014 18.4 0.2 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF4490 PF14892.6 CBY31158.1 - 1.1e-08 35.0 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) KH_1 PF00013.29 CBY31160.1 - 0.00052 19.8 0.3 0.00057 19.7 0.3 1.1 1 0 0 1 1 1 1 KH domain ASH PF15780.5 CBY31161.1 - 0.0099 16.1 0.0 58 4.0 0.0 3.7 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ASH PF15780.5 CBY31162.1 - 3.7e-14 52.7 0.1 0.0001 22.4 0.0 3.6 3 0 0 3 3 3 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY31162.1 - 2.9e-13 49.7 0.0 9.9e-05 22.3 0.0 3.6 3 1 0 3 3 3 3 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CBY31162.1 - 7.8e-08 32.1 0.7 0.00076 19.3 0.1 3.3 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD-like PF14874.6 CBY31162.1 - 0.0015 18.7 0.1 3 8.1 0.0 3.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like Tim54 PF11711.8 CBY31162.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM154 PF15102.6 CBY31162.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family SIS PF01380.22 CBY31163.1 - 8.9e-55 184.1 0.0 5.4e-33 113.6 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CBY31163.1 - 2.6e-15 56.8 0.0 5.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBY31163.1 - 2.1e-10 40.6 0.0 4.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CBY31163.1 - 4.2e-05 22.6 0.0 8e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CBY31163.1 - 8.3e-05 22.6 0.1 0.00062 19.8 0.0 2.3 1 1 1 2 2 2 1 SIS domain HMG_box PF00505.19 CBY31165.1 - 2.6e-15 56.6 2.1 5e-15 55.7 2.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY31165.1 - 1.2e-08 35.4 2.6 2.7e-08 34.3 2.6 1.7 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 CBY31165.1 - 0.00043 19.7 0.6 0.00067 19.0 0.6 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Presenilin PF01080.17 CBY31165.1 - 9.2 4.9 9.4 11 4.6 9.4 1.3 1 0 0 1 1 1 0 Presenilin eRF1_2 PF03464.15 CBY31166.1 - 4.9e-41 140.2 0.1 1.9e-40 138.3 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 CBY31166.1 - 5.4e-18 65.5 0.1 9.8e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 3 acVLRF1 PF18859.1 CBY31166.1 - 3.2e-07 30.7 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CBY31166.1 - 6.9e-05 23.1 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ssl1 PF04056.14 CBY31166.1 - 0.0056 16.5 0.0 0.016 15.1 0.0 1.8 1 1 2 3 3 3 1 Ssl1-like eRF1_1 PF03463.15 CBY31167.1 - 3.1e-16 59.5 0.0 3.8e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 eRF1 domain 1 Zn-ribbon_8 PF09723.10 CBY31168.1 - 0.89 9.7 3.2 2 8.6 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain eRF1_2 PF03464.15 CBY31169.1 - 7.9e-44 149.2 0.3 2.3e-43 147.7 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 CBY31169.1 - 1.3e-28 99.8 0.1 3.1e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CBY31169.1 - 2e-20 73.1 0.0 3.4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 CBY31169.1 - 1.2e-07 32.0 0.0 2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 CBY31169.1 - 2.2e-07 31.2 0.0 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Ssl1 PF04056.14 CBY31169.1 - 0.0076 16.1 0.0 0.038 13.8 0.0 2.2 1 1 1 2 2 2 1 Ssl1-like VWA_2 PF13519.6 CBY31169.1 - 0.081 13.6 0.2 17 6.1 0.0 2.8 3 1 1 4 4 4 0 von Willebrand factor type A domain Zn-ribbon_8 PF09723.10 CBY31170.1 - 0.81 9.9 3.2 1.8 8.7 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DPBB_1 PF03330.18 CBY31172.1 - 0.00035 20.8 1.7 0.00046 20.4 0.3 1.9 2 0 0 2 2 2 1 Lytic transglycolase Sulfotransfer_4 PF17784.1 CBY31173.1 - 6.4e-61 205.9 0.0 7.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31173.1 - 0.023 15.1 0.1 0.18 12.1 0.0 2.3 2 1 1 3 3 3 0 Sulfotransferase family Amidase PF01425.21 CBY31174.1 - 0.16 10.9 0.5 0.22 10.4 0.5 1.2 1 0 0 1 1 1 0 Amidase EMC3_TMCO1 PF01956.16 CBY31174.1 - 0.46 10.2 2.9 0.86 9.3 2.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 CBY31174.1 - 9.3 4.9 9.1 13 4.4 9.1 1.1 1 0 0 1 1 1 0 Presenilin NADHdh PF00146.21 CBY31175.1 - 0.0033 16.8 0.6 0.0033 16.8 0.6 1.1 1 0 0 1 1 1 1 NADH dehydrogenase WD40 PF00400.32 CBY31176.1 - 3.4e-45 151.1 33.1 3.5e-07 30.8 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CBY31176.1 - 1.3e-13 50.6 0.9 2.3e-13 49.8 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CBY31176.1 - 1.6e-11 44.4 7.0 0.1 12.9 0.0 6.5 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CBY31176.1 - 3e-11 42.9 0.3 6.9e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CBY31176.1 - 2.6e-07 29.7 17.5 0.018 13.7 0.6 5.9 3 2 3 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CBY31176.1 - 1.6e-05 24.6 7.4 0.0044 16.6 2.3 3.4 2 2 0 2 2 2 2 PQQ-like domain FAM83 PF07894.12 CBY31176.1 - 0.011 15.3 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 FAM83 A-H DUF5046 PF16465.5 CBY31176.1 - 0.081 12.4 0.4 9.5 5.6 0.1 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 CBY31176.1 - 0.12 12.8 4.7 11 6.6 0.0 5.1 6 2 1 7 7 7 0 PQQ-like domain ACBP PF00887.19 CBY31177.1 - 1.7e-29 101.9 0.5 1.8e-29 101.7 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein SPOB_a PF14689.6 CBY31178.1 - 9.7 6.0 7.9 2.8 7.7 0.1 3.4 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Pkinase PF00069.25 CBY31179.1 - 4.7e-47 160.6 0.0 7.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31179.1 - 1.8e-29 102.9 0.0 3.4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY31179.1 - 3.9e-05 23.1 0.0 0.0002 20.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like NifU PF01106.17 CBY31180.1 - 1.5e-25 89.1 0.0 1.9e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CBY31182.1 - 6.3e-28 96.7 0.0 8.6e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal LRR_8 PF13855.6 CBY31183.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeat RRM_1 PF00076.22 CBY31185.1 - 1.4e-14 53.7 0.9 1.6e-07 31.0 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY31185.1 - 1.2e-05 25.0 0.3 0.16 11.9 0.0 3.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif NPR3 PF03666.13 CBY31185.1 - 4.1 6.1 16.8 0.49 9.1 10.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Indigoidine_A PF04227.12 CBY31186.1 - 3.4e-110 368.0 0.1 3.8e-110 367.8 0.1 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein BCAS2 PF05700.11 CBY31187.1 - 3.9e-69 232.5 8.3 4.6e-69 232.2 8.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) SbcD_C PF12320.8 CBY31187.1 - 0.0031 17.8 5.5 0.051 13.9 2.9 2.3 1 1 1 2 2 2 1 Type 5 capsule protein repressor C-terminal domain DUF3271 PF11675.8 CBY31187.1 - 0.011 15.0 2.9 0.17 11.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3271) Rootletin PF15035.6 CBY31187.1 - 0.019 15.0 7.9 0.019 15.0 7.9 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 CBY31187.1 - 0.019 15.0 8.7 2.5 8.1 6.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rab5-bind PF09311.11 CBY31187.1 - 0.038 13.4 9.2 0.057 12.8 8.7 1.5 1 1 0 1 1 1 0 Rabaptin-like protein Helo_like_N PF17111.5 CBY31187.1 - 0.047 13.1 3.5 0.13 11.6 3.3 1.8 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins HR1 PF02185.16 CBY31187.1 - 0.082 13.0 6.2 0.34 11.1 6.2 2.1 1 1 0 1 1 1 0 Hr1 repeat MEDS PF14417.6 CBY31187.1 - 0.11 12.3 0.1 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF1515 PF07439.11 CBY31187.1 - 0.15 12.1 1.1 0.28 11.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 CBY31187.1 - 0.26 10.8 4.8 0.3 10.6 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZapB PF06005.12 CBY31187.1 - 0.32 11.5 13.6 6.9 7.2 3.1 3.4 2 2 1 3 3 3 0 Cell division protein ZapB Med9 PF07544.13 CBY31187.1 - 0.4 10.8 7.2 3.6 7.7 0.0 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4810 PF16068.5 CBY31187.1 - 0.46 11.1 3.4 18 6.0 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4810) Csm1_N PF18504.1 CBY31187.1 - 0.99 9.8 10.8 0.066 13.6 3.8 2.5 2 1 1 3 3 3 0 Csm1 N-terminal domain LMBR1 PF04791.16 CBY31187.1 - 1.2 8.0 4.0 1.3 7.8 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein KxDL PF10241.9 CBY31187.1 - 2.4 8.5 8.0 11 6.4 0.6 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 CBY31187.1 - 4.2 8.0 8.9 3.6 8.3 6.5 2.2 1 1 1 2 2 2 0 SlyX GIT_CC PF16559.5 CBY31187.1 - 7.1 6.6 12.5 1.4 8.9 2.6 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 CBY31187.1 - 8.6 7.3 11.1 1.6 9.7 5.7 2.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain MA3 PF02847.17 CBY31188.1 - 0.0059 16.6 0.8 0.014 15.4 0.8 1.6 1 0 0 1 1 1 1 MA3 domain DUF1542 PF07564.11 CBY31188.1 - 0.024 14.7 2.9 0.09 12.9 2.9 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Tox-ODYAM1 PF15642.6 CBY31188.1 - 0.093 11.7 4.7 0.13 11.2 4.7 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cryptochrome_C PF12546.8 CBY31188.1 - 0.12 13.0 0.4 0.12 13.0 0.4 2.6 2 1 1 3 3 3 0 Blue/Ultraviolet sensing protein C terminal RNR_Alpha PF17975.1 CBY31188.1 - 0.22 12.0 4.0 0.47 11.0 2.3 2.2 1 1 1 2 2 2 0 Ribonucleotide reductase alpha domain DUF3492 PF11997.8 CBY31188.1 - 2.5 7.8 5.0 3.7 7.2 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3492) DpnI_C PF17726.1 CBY31188.1 - 5.3 7.2 7.8 13 6.0 0.8 2.6 1 1 1 2 2 2 0 Dam-replacing HTH domain Glyco_transf_22 PF03901.17 CBY31189.1 - 1.3e-65 222.3 26.6 1.7e-65 221.9 26.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_60s PF00428.19 CBY31190.1 - 1.3e-20 73.7 8.0 1.6e-20 73.5 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ifi-6-16 PF06140.13 CBY31191.1 - 7.6e-12 45.0 34.3 1.1e-11 44.4 34.3 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family PG_isomerase_N PF18353.1 CBY31191.1 - 2.3 8.6 13.0 3.2 8.2 13.0 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain Raffinose_syn PF05691.12 CBY31192.1 - 4e-05 21.6 0.0 5e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Bac_rhamnosid_C PF17390.2 CBY31192.1 - 0.052 13.4 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Phospholip_A2_1 PF00068.19 CBY31193.1 - 5.6e-12 46.1 10.5 5.6e-12 46.1 10.5 2.1 2 1 0 2 2 2 1 Phospholipase A2 Pox_A21 PF05323.12 CBY31193.1 - 3 8.5 6.0 6.5 7.4 6.0 1.5 1 0 0 1 1 1 0 Poxvirus A21 Protein Gal_Lectin PF02140.18 CBY31194.1 - 1.1e-13 51.4 2.7 3.7e-13 49.7 1.1 2.4 2 1 0 2 2 2 1 Galactose binding lectin domain GHL10 PF02638.15 CBY31198.1 - 2.9e-46 158.0 0.8 3.6e-46 157.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 CBY31198.1 - 0.0073 16.5 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 2 Hypothetical glycosyl hydrolase 6 Cnd1 PF12717.7 CBY31199.1 - 3.5e-32 111.7 17.4 1.6e-29 103.0 0.1 5.8 5 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY31199.1 - 2.3e-10 39.7 11.6 0.0016 17.1 0.1 5.8 3 3 1 5 5 5 5 Adaptin N terminal region Cnd3 PF12719.7 CBY31199.1 - 0.027 13.7 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Cys_Met_Meta_PP PF01053.20 CBY31200.1 - 1.1e-140 468.5 0.0 1.3e-140 468.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CBY31200.1 - 3.8e-10 39.3 0.8 6.7e-08 31.9 0.2 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Met_gamma_lyase PF06838.11 CBY31200.1 - 5.7e-07 28.4 0.0 1.9e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CBY31200.1 - 4.6e-06 26.0 0.1 7.1e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBY31200.1 - 0.041 13.2 0.1 0.089 12.1 0.1 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Baculo_PEP_C PF04513.12 CBY31201.1 - 0.035 14.1 4.8 0.83 9.7 2.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 CBY31201.1 - 0.14 12.4 5.2 0.067 13.5 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Myb_DNA-bind_3 PF12776.7 CBY31201.1 - 0.15 13.1 7.6 2.7 9.0 0.2 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain SlyX PF04102.12 CBY31201.1 - 1.1 10.0 7.2 11 6.8 0.5 2.8 2 1 1 3 3 3 0 SlyX FAM167 PF11652.8 CBY31201.1 - 3.5 8.2 7.2 4.9 7.7 1.6 3.0 1 1 3 4 4 4 0 FAM167 DUF919 PF06034.11 CBY31201.1 - 9.9 6.1 10.5 1.4 8.8 0.5 3.5 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Phospholip_A2_1 PF00068.19 CBY31202.1 - 3.1e-18 66.3 8.0 4.6e-18 65.7 8.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Ig_2 PF13895.6 CBY31203.1 - 3.6e-07 30.4 0.0 0.00034 20.9 0.0 2.8 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY31203.1 - 7.3e-05 23.3 0.0 0.035 14.7 0.0 3.7 1 1 2 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CBY31203.1 - 0.0011 19.0 0.0 0.26 11.4 0.0 2.9 2 2 0 2 2 2 2 Immunoglobulin I-set domain AA_permease_2 PF13520.6 CBY31204.1 - 4.5e-35 121.3 42.3 5.6e-35 121.0 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY31204.1 - 2.6e-14 52.7 37.1 3.2e-14 52.4 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease Asparaginase PF00710.20 CBY31205.1 - 2.1e-43 148.1 0.0 3.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 CBY31205.1 - 6.7e-25 87.5 0.0 4.2e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 CBY31205.1 - 2.5e-21 76.0 0.2 1.3e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 CBY31205.1 - 3.6e-21 75.3 0.1 6.6e-07 29.8 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY31205.1 - 7e-18 64.2 0.0 9.6e-06 25.8 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBY31205.1 - 6.3e-17 59.9 0.0 4.2e-05 23.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY31205.1 - 1.5e-13 50.7 0.1 6.3e-08 32.7 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF2389 PF09493.10 CBY31205.1 - 0.023 15.3 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) SSF PF00474.17 CBY31206.1 - 4.5e-10 39.0 4.5 8.9e-10 38.0 4.5 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4231 PF14015.6 CBY31206.1 - 6.6 7.3 11.5 7.3 7.1 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) bZIP_1 PF00170.21 CBY31207.1 - 0.017 15.2 5.9 0.081 13.0 1.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor PspB PF06667.12 CBY31207.1 - 0.017 15.2 1.0 0.017 15.2 1.0 1.7 2 0 0 2 2 1 0 Phage shock protein B Phage_HK97_TLTM PF06120.11 CBY31207.1 - 0.02 14.1 4.1 0.025 13.8 4.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein ATG16 PF08614.11 CBY31207.1 - 0.024 14.9 5.1 0.024 14.9 5.1 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 CBY31207.1 - 0.087 12.1 2.6 0.11 11.7 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 CBY31207.1 - 0.14 12.6 5.9 0.21 12.0 0.7 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Wtap PF17098.5 CBY31207.1 - 0.21 11.5 5.8 39 4.2 5.8 2.3 1 1 0 1 1 1 0 WTAP/Mum2p family SIR4_SID PF16991.5 CBY31207.1 - 0.25 11.4 2.7 0.33 11.0 2.7 1.2 1 0 0 1 1 1 0 Sir4 SID domain Seadorna_VP6 PF07407.11 CBY31207.1 - 0.25 10.2 1.1 3.9 6.3 0.0 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein Exonuc_VII_L PF02601.15 CBY31207.1 - 0.45 10.0 4.8 0.52 9.8 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CBY31207.1 - 0.49 10.6 7.3 0.28 11.4 4.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY31207.1 - 0.54 9.6 5.0 0.73 9.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DsrD PF08679.11 CBY31207.1 - 0.62 10.4 3.7 1.9 8.8 0.4 2.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) UPF0242 PF06785.11 CBY31207.1 - 0.71 10.0 12.8 0.068 13.3 5.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 CBY31207.1 - 0.73 9.9 10.2 2.6 8.1 5.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 CBY31207.1 - 1 10.1 6.5 8.6 7.1 0.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 CBY31207.1 - 1.8 9.2 8.5 0.43 11.2 1.8 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 CBY31207.1 - 1.9 7.5 6.1 2.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2015 PF09435.10 CBY31207.1 - 2.5 8.0 6.3 1.1 9.1 3.7 1.8 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF2015) Csm1_N PF18504.1 CBY31207.1 - 4.3 7.8 10.8 1.1 9.6 3.5 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF16 PF01519.16 CBY31207.1 - 7.4 7.1 10.0 3.6 8.1 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 PLAC8 PF04749.17 CBY31208.1 - 1.4e-21 77.3 14.2 1.6e-21 77.1 14.2 1.0 1 0 0 1 1 1 1 PLAC8 family Sulfotransfer_2 PF03567.14 CBY31209.1 - 4.6e-11 43.1 3.7 9.8e-11 42.0 3.7 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY31209.1 - 0.0045 16.5 0.2 0.022 14.2 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain TAFA PF12020.8 CBY31210.1 - 2.6 8.6 14.5 1 9.8 0.0 4.3 5 0 0 5 5 5 0 TAFA family Pkinase_Tyr PF07714.17 CBY31211.1 - 1.8e-55 188.0 0.4 3.4e-54 183.8 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY31211.1 - 4.8e-34 117.9 0.9 2.1e-32 112.5 0.9 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY31211.1 - 0.001 18.0 0.1 0.0016 17.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4467 PF14729.6 CBY31211.1 - 0.0049 17.2 1.8 0.0088 16.4 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function with cystatin-like fold (DUF4467) Pkinase PF00069.25 CBY31212.1 - 1.1e-50 172.5 0.0 1.6e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31212.1 - 4.9e-19 68.6 0.0 7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY31212.1 - 0.0011 19.0 0.0 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY31212.1 - 0.003 16.4 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CBY31212.1 - 0.098 12.2 0.1 0.098 12.2 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Sulfotransfer_2 PF03567.14 CBY31213.1 - 1.5e-10 41.4 5.7 1.9e-10 41.1 5.7 1.0 1 0 0 1 1 1 1 Sulfotransferase family Orbi_NS1 PF01718.16 CBY31213.1 - 0.036 12.5 0.3 0.046 12.2 0.3 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein zf-CSL PF05207.13 CBY31213.1 - 0.079 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger Glyco_hydro_9 PF00759.19 CBY31214.1 - 2e-122 409.6 3.8 2.4e-122 409.3 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ion_trans PF00520.31 CBY31215.1 - 1.6e-213 705.5 88.9 1.1e-62 211.4 7.7 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CBY31215.1 - 2.9e-09 36.1 88.8 0.00035 19.4 6.1 10.4 6 4 2 8 8 8 8 Polycystin cation channel GPHH PF16905.5 CBY31215.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Beta-lactamase PF00144.24 CBY31216.1 - 5.5e-29 101.5 0.0 1.3e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Dynactin PF12455.8 CBY31217.1 - 3.4e-43 147.9 0.2 3.4e-43 147.9 0.2 3.4 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 CBY31217.1 - 1.3e-21 76.4 0.9 2.2e-21 75.6 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.15 CBY31217.1 - 0.0042 16.8 3.2 0.0042 16.8 3.2 7.1 5 4 2 7 7 7 2 Septum formation initiator Pkinase PF00069.25 CBY31218.1 - 4.8e-59 199.9 0.2 9e-59 199.0 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31218.1 - 1.8e-37 129.0 0.0 2.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY31218.1 - 1e-09 37.7 0.0 1.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY31218.1 - 7.2e-05 22.2 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY31218.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY31218.1 - 0.0028 17.6 0.0 0.037 14.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBY31218.1 - 0.031 13.9 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CBY31218.1 - 0.046 13.3 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CBY31218.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Band_7 PF01145.25 CBY31219.1 - 3.1e-29 102.3 0.4 3.1e-29 102.3 0.4 2.3 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CBY31219.1 - 3.9e-21 74.9 0.7 1.2e-20 73.3 0.2 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CBY31219.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family Tmemb_cc2 PF10267.9 CBY31220.1 - 0.00016 21.0 1.4 0.00019 20.8 1.4 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Chitin_synth_2 PF03142.15 CBY31221.1 - 1.9e-28 99.4 1.4 1.6e-23 83.1 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CBY31221.1 - 3.2e-11 43.5 7.7 3.2e-11 43.5 7.7 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CBY31221.1 - 3.2e-10 40.3 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CBY31221.1 - 0.041 13.7 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 RVT_1 PF00078.27 CBY31222.1 - 2.6e-12 46.7 0.0 7.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SPECT1 PF18680.1 CBY31222.1 - 0.07 12.8 0.6 0.45 10.2 0.1 2.5 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 Mtc PF03820.17 CBY31224.1 - 1.1e-63 215.2 5.2 1.2e-63 215.0 5.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ost5 PF05251.12 CBY31224.1 - 0.069 13.4 1.0 0.069 13.4 1.0 2.0 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF3313 PF11769.8 CBY31224.1 - 0.072 12.9 0.3 0.19 11.5 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) AAA PF00004.29 CBY31225.1 - 9.8e-44 149.0 0.0 3.5e-43 147.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CBY31225.1 - 6e-28 98.0 2.8 1.8e-27 96.5 2.8 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CBY31225.1 - 2e-10 40.3 0.0 4.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBY31225.1 - 6.6e-05 23.4 0.0 0.026 14.9 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY31225.1 - 0.00014 21.9 0.2 0.0073 16.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBY31225.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CBY31225.1 - 0.00018 21.3 0.0 0.00051 19.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY31225.1 - 0.0003 20.9 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBY31225.1 - 0.00032 21.2 1.1 0.0021 18.6 0.0 2.8 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 CBY31225.1 - 0.011 15.1 0.2 0.026 13.9 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY31225.1 - 0.011 15.5 0.4 0.085 12.6 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBY31225.1 - 0.013 15.5 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBY31225.1 - 0.015 15.5 0.5 0.8 10.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CBY31225.1 - 0.024 15.1 0.5 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY31225.1 - 0.054 12.8 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 CBY31225.1 - 0.08 12.6 0.0 0.31 10.7 0.0 1.9 1 1 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 CBY31225.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PHD PF00628.29 CBY31226.1 - 0.00054 19.8 10.7 0.00054 19.8 10.7 2.8 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.25 CBY31226.1 - 0.013 15.5 0.1 0.038 14.1 0.1 1.9 1 0 0 1 1 1 0 Bromodomain ERCC3_RAD25_C PF16203.5 CBY31226.1 - 0.029 13.6 0.0 0.067 12.4 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF4094 PF13334.6 CBY31226.1 - 0.045 14.2 1.9 0.14 12.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) YyzF PF14116.6 CBY31226.1 - 0.12 12.4 4.6 8.4 6.5 0.1 3.5 3 1 0 3 3 3 0 YyzF-like protein Ilm1 PF10311.9 CBY31226.1 - 0.16 11.6 0.0 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Zf_RING PF16744.5 CBY31226.1 - 0.3 11.2 17.1 0.059 13.5 7.8 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger MoCF_biosynth PF00994.24 CBY31227.1 - 4.1e-59 198.4 0.1 5e-32 110.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CBY31227.1 - 2.3e-38 131.4 0.1 8.8e-38 129.5 0.1 2.0 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CBY31227.1 - 3.4e-12 46.4 0.0 7.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DEAD PF00270.29 CBY31228.1 - 3.7e-38 131.1 0.0 7.6e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY31228.1 - 2.4e-25 89.0 0.3 1.3e-23 83.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY31228.1 - 3.2e-09 37.0 0.0 7.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY31228.1 - 1.2e-05 25.6 0.7 0.00013 22.3 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY31228.1 - 0.0018 18.6 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CBY31228.1 - 0.013 14.3 0.0 3.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 CBY31228.1 - 0.051 13.5 0.5 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain ING PF12998.7 CBY31229.1 - 1.6e-23 83.2 4.6 2.1e-23 82.8 4.6 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CBY31229.1 - 1.8e-05 24.5 8.2 3.2e-05 23.7 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY31229.1 - 0.0066 16.0 2.8 0.012 15.1 2.8 1.5 1 0 0 1 1 1 1 PHD-finger Nup54 PF13874.6 CBY31229.1 - 0.011 15.9 0.6 0.015 15.4 0.6 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF3160 PF11369.8 CBY31229.1 - 0.025 13.1 1.9 0.033 12.7 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) THDPS_N_2 PF14805.6 CBY31229.1 - 0.038 14.2 0.4 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Muted PF14942.6 CBY31229.1 - 0.069 13.5 6.9 0.099 13.0 6.9 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF724 PF05266.14 CBY31229.1 - 0.12 12.2 5.5 0.16 11.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 CBY31229.1 - 0.16 12.2 4.5 1 9.5 5.2 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 CBY31229.1 - 0.19 10.9 4.3 0.24 10.6 4.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-HC5HC2H PF13771.6 CBY31229.1 - 0.36 11.1 4.6 0.1 12.9 1.1 2.0 2 1 0 2 2 2 0 PHD-like zinc-binding domain DUF4164 PF13747.6 CBY31229.1 - 0.59 10.5 6.5 5 7.5 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TMPIT PF07851.13 CBY31229.1 - 0.68 9.1 6.2 0.96 8.6 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-C4pol PF14260.6 CBY31229.1 - 3.4 8.2 8.5 0.75 10.3 0.9 3.0 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta PSP1 PF04468.12 CBY31230.1 - 0.047 14.0 0.3 0.19 12.0 0.3 2.0 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Methyltransf_28 PF02636.17 CBY31232.1 - 4.6e-61 206.8 0.0 5.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ndc80_HEC PF03801.13 CBY31232.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family zf-TAZ PF02135.16 CBY31233.1 - 0.14 12.6 5.4 0.26 11.8 5.4 1.4 1 0 0 1 1 1 0 TAZ zinc finger zf-C3HC4_4 PF15227.6 CBY31234.1 - 3.5e-07 30.3 13.7 6.1e-07 29.5 13.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY31234.1 - 2.6e-06 27.2 9.6 4e-06 26.6 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY31234.1 - 3e-06 27.4 12.9 4.8e-06 26.8 12.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY31234.1 - 4.9e-06 26.3 13.5 7.8e-06 25.6 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY31234.1 - 9e-06 25.5 14.0 1.5e-05 24.8 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY31234.1 - 2.3e-05 24.3 11.5 4.7e-05 23.3 11.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY31234.1 - 0.029 14.3 14.1 0.096 12.7 14.5 1.7 1 1 1 2 2 2 0 zinc-RING finger domain U-box PF04564.15 CBY31234.1 - 0.048 13.8 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CBY31234.1 - 0.11 12.3 9.6 0.17 11.7 9.6 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CBY31234.1 - 0.2 11.6 14.8 2.9 7.8 15.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 CBY31234.1 - 0.42 10.9 0.3 0.42 10.9 0.3 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CBY31234.1 - 0.43 11.1 14.2 1.3 9.5 2.7 3.1 2 1 1 3 3 3 0 Zinc-finger double domain zf-RING_6 PF14835.6 CBY31234.1 - 0.46 10.4 4.0 0.82 9.6 4.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DTHCT PF08070.11 CBY31234.1 - 3.1 8.6 17.0 2.7 8.8 14.5 2.0 1 1 1 2 2 2 0 DTHCT (NUC029) region HEAT_2 PF13646.6 CBY31235.1 - 4.8e-06 26.9 0.0 0.013 15.9 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 CBY31235.1 - 2.7e-05 24.0 0.0 1.1 9.7 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CBY31235.1 - 0.0012 18.9 9.7 0.2 11.7 0.2 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF762 PF05555.11 CBY31235.1 - 0.076 12.6 4.5 0.072 12.7 1.3 2.3 1 1 1 2 2 2 0 Coxiella burnetii protein of unknown function (DUF762) ELFV_dehydrog PF00208.21 CBY31237.1 - 1.6e-74 250.7 0.1 1.9e-74 250.5 0.1 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBY31237.1 - 3e-07 30.4 0.0 8.4e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Integrase_H2C2 PF17921.1 CBY31239.1 - 0.00034 20.7 0.1 0.00081 19.5 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Ndufs5 PF10200.9 CBY31239.1 - 0.0045 17.2 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF1173 PF06666.11 CBY31239.1 - 0.057 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Dynamin_M PF01031.20 CBY31240.1 - 5.3e-92 308.1 11.2 5.3e-92 308.1 11.2 2.2 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY31240.1 - 2.3e-56 190.4 0.0 8.2e-56 188.7 0.0 2.0 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CBY31240.1 - 2.7e-25 88.3 4.7 1.2e-24 86.3 4.7 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBY31240.1 - 1.1e-05 25.9 0.3 2.4e-05 24.8 0.3 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY31240.1 - 8.7e-05 22.6 0.0 0.00047 20.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RecG_N PF17190.4 CBY31240.1 - 0.48 11.2 4.2 0.84 10.4 0.5 3.3 2 1 1 3 3 3 0 RecG N-terminal helical domain Kelch_6 PF13964.6 CBY31241.1 - 0.012 15.9 0.0 1.9 8.9 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY31242.1 - 0.16 12.0 0.5 27 5.0 0.2 2.6 2 0 0 2 2 2 0 Kelch motif DDE_Tnp_IS1 PF03400.13 CBY31244.1 - 0.027 14.8 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 IS1 transposase BOFC_N PF08977.10 CBY31244.1 - 0.062 13.3 2.0 0.12 12.4 2.0 1.4 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal DNA_pol_phi PF04931.13 CBY31245.1 - 3.3 5.7 10.4 3.8 5.5 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Clat_adaptor_s PF01217.20 CBY31246.1 - 3.1e-58 195.7 4.8 3.4e-58 195.6 4.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ITI_HC_C PF06668.12 CBY31247.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus ITI_HC_C PF06668.12 CBY31248.1 - 0.00046 19.9 0.6 0.001 18.8 0.0 1.9 2 1 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus CSRNP_N PF16019.5 CBY31249.1 - 3.9e-45 154.5 16.0 3.9e-45 154.5 16.0 2.9 3 1 0 3 3 3 1 Cysteine/serine-rich nuclear protein N-terminus HisKA_2 PF07568.12 CBY31249.1 - 0.093 12.8 0.5 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase Perilipin PF03036.16 CBY31250.1 - 0.011 14.8 0.3 0.015 14.3 0.3 1.2 1 0 0 1 1 1 0 Perilipin family Gly-zipper_Omp PF13488.6 CBY31250.1 - 0.029 14.4 3.0 0.054 13.5 3.0 1.5 1 0 0 1 1 1 0 Glycine zipper EF1_GNE PF00736.19 CBY31250.1 - 0.07 13.3 1.0 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain ING PF12998.7 CBY31252.1 - 2.6e-09 37.6 4.0 3.7e-09 37.1 4.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CBY31252.1 - 0.0014 18.5 1.6 0.0023 17.8 1.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CBY31252.1 - 0.0029 17.8 1.9 0.0084 16.3 0.1 2.2 1 1 1 2 2 2 1 PHD-like zinc-binding domain CENP-Q PF13094.6 CBY31252.1 - 0.0097 16.1 2.8 0.013 15.8 2.8 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.11 CBY31252.1 - 3.4 8.2 7.1 3.8 8.0 0.3 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lectin_C PF00059.21 CBY31253.1 - 5e-46 155.9 19.8 1.9e-14 54.3 0.4 4.5 4 0 0 4 4 4 4 Lectin C-type domain Trefoil PF00088.18 CBY31253.1 - 2.7e-05 24.0 5.3 0.00011 22.0 5.3 2.1 1 0 0 1 1 1 1 Trefoil (P-type) domain UL45 PF05473.12 CBY31253.1 - 0.13 11.8 3.2 13 5.3 0.0 3.2 3 0 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like MORN PF02493.20 CBY31253.1 - 0.51 10.3 2.5 2.7 8.1 0.1 3.5 4 0 0 4 4 4 0 MORN repeat Phospholip_A2_1 PF00068.19 CBY31254.1 - 1.6e-08 35.0 0.4 1.6e-08 35.0 0.4 1.9 2 0 0 2 2 2 1 Phospholipase A2 PEN-2 PF10251.9 CBY31255.1 - 0.0062 16.9 2.8 0.0087 16.5 0.8 2.2 2 0 0 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase PsbT PF01405.17 CBY31255.1 - 2.6 7.9 5.1 22 5.0 0.1 3.2 3 0 0 3 3 3 0 Photosystem II reaction centre T protein DNA_pol_A_exo1 PF01612.20 CBY31256.1 - 4e-12 46.2 0.0 1.2e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.7 CBY31256.1 - 0.034 14.7 1.0 0.078 13.5 1.0 1.6 1 0 0 1 1 1 0 Stc1 domain Tnp_zf-ribbon_2 PF13842.6 CBY31256.1 - 1.2 10.0 4.9 1.5 9.7 1.9 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon ENTH PF01417.20 CBY31257.1 - 4.9e-41 139.7 0.0 7.6e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TPR_19 PF14559.6 CBY31260.1 - 1.3e-18 67.2 0.0 4.2e-07 30.4 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY31260.1 - 1.2e-10 41.3 0.0 0.048 14.5 0.0 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY31260.1 - 1.5e-07 31.9 0.0 0.011 16.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY31260.1 - 0.00024 20.4 0.1 0.078 12.2 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY31260.1 - 0.0015 18.2 0.1 0.004 16.9 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 CBY31260.1 - 0.0024 17.9 0.1 14 6.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY31260.1 - 0.0037 17.5 0.0 20 5.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat S1 PF00575.23 CBY31260.1 - 0.0066 16.8 2.3 4.6 7.6 0.0 3.1 2 1 0 2 2 2 2 S1 RNA binding domain TPR_12 PF13424.6 CBY31260.1 - 0.007 16.6 0.0 27 5.1 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31260.1 - 0.0082 16.2 0.0 2.9 8.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY31260.1 - 0.012 15.8 0.0 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY31260.1 - 0.025 14.0 0.6 0.97 8.7 0.1 2.6 1 1 1 2 2 2 0 MalT-like TPR region ChAPs PF09295.10 CBY31260.1 - 0.032 13.2 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY31260.1 - 0.043 14.4 0.1 56 4.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 CBY31260.1 - 0.52 10.2 4.4 18 5.2 0.0 3.4 1 1 3 4 4 4 0 Suppressor of forked protein (Suf) DUF2031 PF09592.10 CBY31260.1 - 4.7 6.7 8.7 0.12 11.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) IP_trans PF02121.18 CBY31261.1 - 8.7e-40 136.8 0.7 1.2e-39 136.4 0.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein IP_trans PF02121.18 CBY31262.1 - 1.6e-19 70.5 1.1 1.8e-19 70.3 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Lectin_C PF00059.21 CBY31263.1 - 8.7e-05 23.2 1.4 0.00044 20.9 0.0 2.4 3 0 0 3 3 3 1 Lectin C-type domain DUF5010_C PF18099.1 CBY31263.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain Aldose_epim PF01263.20 CBY31264.1 - 3.6e-70 236.7 0.1 4e-70 236.5 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4751 PF15942.5 CBY31264.1 - 0.11 12.4 0.7 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4751) Astacin PF01400.24 CBY31266.1 - 1.6e-23 83.3 0.2 1.2e-21 77.2 0.2 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY31266.1 - 0.0057 16.9 2.6 0.019 15.2 2.6 1.9 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A BAR_3_WASP_bdg PF10456.9 CBY31267.1 - 4.3e-23 82.0 0.1 4.8e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PX PF00787.24 CBY31268.1 - 4e-21 75.1 0.1 7.1e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 CBY31268.1 - 2e-14 52.9 0.1 4.9e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY31268.1 - 1.5e-10 40.8 0.1 2.7e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY31268.1 - 2.6e-10 39.8 0.0 7.8e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Chitin_synth_2 PF03142.15 CBY31269.1 - 1.3e-08 33.9 8.1 4.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Choline_sulf_C PF12411.8 CBY31269.1 - 0.067 13.0 0.7 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal ILEI PF15711.5 CBY31270.1 - 1.2e-17 64.1 0.1 1.7e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Interleukin-like EMT inducer Osw5 PF17062.5 CBY31271.1 - 0.068 13.3 0.9 0.11 12.6 0.9 1.3 1 0 0 1 1 1 0 Outer spore wall 5 C2 PF00168.30 CBY31272.1 - 1.1e-42 144.4 0.9 1.9e-27 95.6 0.0 2.6 2 1 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY31272.1 - 0.0012 18.4 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 2 CEP76 C2 domain PAG PF15347.6 CBY31272.1 - 0.0083 15.2 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched DUF4489 PF14879.6 CBY31272.1 - 0.009 16.1 0.5 0.021 14.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4489) MAP17 PF15807.5 CBY31272.1 - 0.0091 16.2 0.7 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM52 PF14979.6 CBY31272.1 - 0.039 13.9 0.3 0.077 12.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane 52 DOCK-C2 PF14429.6 CBY31272.1 - 0.047 13.5 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Transglut_C PF00927.22 CBY31272.1 - 0.13 12.4 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain EF-hand_6 PF13405.6 CBY31273.1 - 2e-14 52.2 0.6 1.6e-06 27.6 0.2 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY31273.1 - 3.7e-14 51.1 0.4 5.4e-06 25.6 0.3 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY31273.1 - 5.9e-13 49.1 0.4 3.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY31273.1 - 7.8e-09 35.3 1.0 0.0034 17.2 0.0 3.1 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31273.1 - 4.9e-08 32.1 6.6 1.5e-05 24.3 0.8 2.9 3 0 0 3 3 3 2 EF hand TRCF PF03461.15 CBY31273.1 - 0.033 14.6 0.1 0.054 13.9 0.1 1.3 1 0 0 1 1 1 0 TRCF domain EF-hand_9 PF14658.6 CBY31273.1 - 0.051 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY31273.1 - 0.07 13.5 0.1 0.29 11.5 0.1 1.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY31273.1 - 0.099 12.6 0.1 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Zona_pellucida PF00100.23 CBY31274.1 - 2.4e-20 73.4 0.0 2.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain fn3 PF00041.21 CBY31275.1 - 1.4e-41 140.7 7.0 6.8e-12 45.6 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY31275.1 - 3.4e-06 27.5 9.5 1.4 9.5 0.1 5.8 5 2 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Laminin_G_3 PF13385.6 CBY31275.1 - 2.3e-05 24.6 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 CBY31275.1 - 7.2e-05 22.9 4.4 7.2e-05 22.9 4.4 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.10 CBY31275.1 - 0.00027 21.2 0.0 1.3 9.4 0.0 4.4 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III EGF PF00008.27 CBY31275.1 - 0.0012 19.1 1.8 0.0027 18.0 1.8 1.6 1 0 0 1 1 1 1 EGF-like domain TQ PF18202.1 CBY31275.1 - 0.0022 18.5 3.5 8.8 6.9 0.1 4.0 3 1 1 4 4 4 2 T-Q ester bond containing domain CBM_4_9 PF02018.17 CBY31275.1 - 0.022 15.0 4.4 0.073 13.3 0.4 3.5 3 1 1 4 4 4 0 Carbohydrate binding domain DUF2369 PF10179.9 CBY31275.1 - 0.053 13.9 0.1 5.9 7.4 0.1 3.2 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Plasmod_Pvs28 PF06247.11 CBY31275.1 - 0.06 13.7 6.5 0.15 12.4 6.5 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain EB PF01683.18 CBY31275.1 - 0.074 13.4 2.4 0.23 11.8 2.4 1.7 1 0 0 1 1 1 0 EB module hEGF PF12661.7 CBY31275.1 - 0.088 13.5 1.0 0.22 12.2 1.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY31275.1 - 0.14 12.2 3.7 0.34 11.0 3.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY31275.1 - 0.23 11.7 3.6 0.63 10.3 3.6 1.7 1 0 0 1 1 1 0 EGF domain fn3 PF00041.21 CBY31276.1 - 1.4e-41 140.7 7.0 6.8e-12 45.6 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY31276.1 - 3.4e-06 27.5 9.5 1.4 9.5 0.1 5.8 5 2 0 5 5 5 2 Purple acid Phosphatase, N-terminal domain Laminin_G_3 PF13385.6 CBY31276.1 - 2.3e-05 24.6 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_CA PF07645.15 CBY31276.1 - 7.2e-05 22.9 4.4 7.2e-05 22.9 4.4 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain Interfer-bind PF09294.10 CBY31276.1 - 0.00027 21.2 0.0 1.3 9.4 0.0 4.4 3 1 1 4 4 4 1 Interferon-alpha/beta receptor, fibronectin type III EGF PF00008.27 CBY31276.1 - 0.0012 19.1 1.8 0.0027 18.0 1.8 1.6 1 0 0 1 1 1 1 EGF-like domain TQ PF18202.1 CBY31276.1 - 0.0022 18.5 3.5 8.8 6.9 0.1 4.0 3 1 1 4 4 4 2 T-Q ester bond containing domain CBM_4_9 PF02018.17 CBY31276.1 - 0.022 15.0 4.4 0.073 13.3 0.4 3.5 3 1 1 4 4 4 0 Carbohydrate binding domain DUF2369 PF10179.9 CBY31276.1 - 0.053 13.9 0.1 5.9 7.4 0.1 3.2 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) Plasmod_Pvs28 PF06247.11 CBY31276.1 - 0.06 13.7 6.5 0.15 12.4 6.5 1.7 1 0 0 1 1 1 0 Pvs28 EGF domain EB PF01683.18 CBY31276.1 - 0.074 13.4 2.4 0.23 11.8 2.4 1.7 1 0 0 1 1 1 0 EB module hEGF PF12661.7 CBY31276.1 - 0.088 13.5 1.0 0.22 12.2 1.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY31276.1 - 0.14 12.2 3.7 0.34 11.0 3.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY31276.1 - 0.23 11.7 3.6 0.63 10.3 3.6 1.7 1 0 0 1 1 1 0 EGF domain DAO PF01266.24 CBY31279.1 - 9.5e-05 22.1 0.0 9.8e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 CBY31279.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Taxilin PF09728.9 CBY31281.1 - 0.0073 15.5 28.5 0.0088 15.3 14.2 2.0 1 1 1 2 2 2 1 Myosin-like coiled-coil protein UPF0449 PF15136.6 CBY31281.1 - 0.014 15.8 18.1 0.34 11.4 8.9 3.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 CALCOCO1 PF07888.11 CBY31281.1 - 0.032 13.1 29.2 0.26 10.1 28.6 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 CBY31281.1 - 0.066 13.7 31.4 0.44 11.0 7.6 3.3 1 1 1 3 3 3 0 Cell division protein ZapB DUF3450 PF11932.8 CBY31281.1 - 0.2 10.9 24.8 0.32 10.2 5.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 CBY31281.1 - 0.2 12.1 7.2 0.95 10.0 0.3 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CBY31281.1 - 0.21 10.4 33.4 0.79 8.6 8.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein OrfB_IS605 PF01385.19 CBY31281.1 - 0.23 11.7 4.5 0.25 11.6 1.6 2.0 2 0 0 2 2 2 0 Probable transposase Macoilin PF09726.9 CBY31281.1 - 0.34 9.4 25.2 0.42 9.1 25.2 1.0 1 0 0 1 1 1 0 Macoilin family Chal_sti_synt_N PF00195.19 CBY31281.1 - 0.38 10.2 4.1 0.16 11.4 0.5 1.9 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain GHMP_kinases_C PF08544.13 CBY31281.1 - 0.43 11.0 7.0 9.1 6.7 2.5 3.9 1 1 2 3 3 3 0 GHMP kinases C terminal Seryl_tRNA_N PF02403.22 CBY31281.1 - 0.86 9.9 31.9 2.7 8.3 12.6 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 CBY31281.1 - 0.91 10.2 21.0 15 6.2 1.7 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Sec34 PF04136.15 CBY31281.1 - 0.99 9.3 15.4 2.6 7.9 4.3 2.7 1 1 3 4 4 4 0 Sec34-like family Cluap1 PF10234.9 CBY31281.1 - 1.7 8.0 25.5 4.2 6.7 9.6 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 JIP_LZII PF16471.5 CBY31281.1 - 2.7 8.2 28.6 2 8.6 11.3 3.5 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II PIN_2 PF10130.9 CBY31281.1 - 3 8.1 11.9 0.64 10.2 6.4 2.5 1 1 1 2 2 2 0 PIN domain SYCE1 PF15233.6 CBY31281.1 - 3.2 7.8 31.7 0.25 11.4 9.0 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 PRKG1_interact PF15898.5 CBY31281.1 - 3.4 8.6 23.6 3 8.8 13.1 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG17 PF04108.12 CBY31281.1 - 4.2 6.4 19.6 0.16 11.1 9.4 2.2 1 1 0 2 2 2 0 Autophagy protein Apg17 AAA_13 PF13166.6 CBY31281.1 - 4.4 5.8 21.9 5.1 5.6 21.9 1.0 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 CBY31281.1 - 4.5 7.3 17.7 3.2 7.8 2.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ASD2 PF08687.11 CBY31281.1 - 4.5 6.7 23.0 0.091 12.3 9.0 2.1 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 ESP PF16590.5 CBY31281.1 - 6.1 7.2 8.7 1.6 9.0 2.2 2.5 1 1 0 2 2 2 0 Exocrine gland-secreting peptide DUF4250 PF14056.6 CBY31281.1 - 8.1 6.5 6.0 8.3 6.4 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4250) CorA PF01544.18 CBY31281.1 - 8.4 5.6 9.5 13 5.0 9.5 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein T-box PF00907.22 CBY31282.1 - 1.1e-74 250.7 0.0 1.5e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 T-box TRAPP PF04051.16 CBY31284.1 - 3.2e-29 101.5 0.0 3.7e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CREPT PF16566.5 CBY31285.1 - 1.8e-39 135.2 3.0 3.8e-39 134.2 3.0 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CBY31285.1 - 2.3e-16 60.3 0.4 8.3e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TPPII_N PF12583.8 CBY31285.1 - 0.043 14.4 1.6 0.07 13.7 0.9 1.7 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DUF3209 PF11483.8 CBY31285.1 - 0.084 13.3 0.4 0.18 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Syntaxin_2 PF14523.6 CBY31285.1 - 0.23 11.8 3.0 0.19 12.1 0.7 2.1 2 0 0 2 2 2 0 Syntaxin-like protein BLOC1_2 PF10046.9 CBY31285.1 - 0.36 11.2 5.0 9.8 6.6 1.9 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY31285.1 - 0.5 9.2 5.4 2.3 7.0 2.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CBY31285.1 - 0.59 10.3 5.8 0.22 11.7 0.6 2.9 3 0 0 3 3 3 0 bZIP transcription factor Tropomyosin_1 PF12718.7 CBY31285.1 - 2.1 8.5 7.2 1.6 8.9 3.7 2.2 2 0 0 2 2 2 0 Tropomyosin like YabA PF06156.13 CBY31285.1 - 6.3 7.5 6.1 3.3 8.4 1.8 2.4 2 0 0 2 2 2 0 Initiation control protein YabA COBRA1 PF06209.13 CBY31286.1 - 0.0045 15.9 0.3 0.0057 15.6 0.3 1.1 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Vfa1 PF08432.10 CBY31286.1 - 1 9.7 14.9 1.6 9.0 14.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TMEM214 PF10151.9 CBY31286.1 - 7.9 4.8 12.9 8.8 4.6 12.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator COBRA1 PF06209.13 CBY31287.1 - 5.5e-57 193.7 2.0 5.5e-57 193.7 2.0 1.6 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) DUF496 PF04363.12 CBY31287.1 - 0.0023 17.9 0.1 0.64 10.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF496) DUF3450 PF11932.8 CBY31288.1 - 0.0017 17.7 7.2 0.0017 17.7 7.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 CBY31288.1 - 0.019 14.9 12.2 0.019 14.9 12.2 4.0 1 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Filament PF00038.21 CBY31288.1 - 0.029 14.0 20.6 0.3 10.6 3.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 CBY31288.1 - 0.27 11.3 23.6 2.3 8.3 5.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 CBY31288.1 - 0.28 11.8 10.0 11 6.7 0.7 3.3 1 1 2 3 3 3 0 SlyX NPV_P10 PF05531.12 CBY31288.1 - 0.52 10.8 4.9 8.1 7.0 2.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rab5-bind PF09311.11 CBY31288.1 - 0.7 9.2 20.7 1.2 8.5 12.0 2.0 1 1 1 2 2 2 0 Rabaptin-like protein Spc7 PF08317.11 CBY31288.1 - 1 8.2 23.3 5.3 5.8 22.8 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 CBY31288.1 - 1.3 9.4 22.4 2.8 8.3 3.9 4.0 2 2 1 3 3 3 0 Csm1 N-terminal domain Fez1 PF06818.15 CBY31288.1 - 1.4 9.3 22.3 3.5 8.0 2.3 2.0 1 1 1 2 2 2 0 Fez1 HAUS6_N PF14661.6 CBY31288.1 - 1.5 8.3 18.8 2.5 7.6 8.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4201 PF13870.6 CBY31288.1 - 1.7 8.3 23.6 0.61 9.8 11.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4695 PF15766.5 CBY31288.1 - 2.2 8.5 10.6 3 8.1 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4695) DUF812 PF05667.11 CBY31288.1 - 2.3 7.0 23.9 11 4.8 23.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Vir_act_alpha_C PF10400.9 CBY31288.1 - 2.5 8.8 9.5 5.3 7.8 0.3 3.1 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF4140 PF13600.6 CBY31288.1 - 2.6 8.6 13.4 28 5.2 6.1 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.11 CBY31288.1 - 2.6 8.2 26.2 12 6.1 12.5 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Rx_N PF18052.1 CBY31288.1 - 6 7.2 10.0 1.6 9.1 1.6 2.6 1 1 0 2 2 2 0 Rx N-terminal domain M PF02370.16 CBY31288.1 - 6.5 7.7 14.8 39 5.3 0.1 5.0 3 2 1 4 4 4 0 M protein repeat AAA_13 PF13166.6 CBY31288.1 - 7.1 5.1 21.7 2 7.0 10.9 2.0 1 1 0 2 2 2 0 AAA domain APG6_N PF17675.1 CBY31288.1 - 7.2 7.2 29.5 39 4.8 17.4 2.9 1 1 1 2 2 1 0 Apg6 coiled-coil region HIT PF01230.23 CBY31289.1 - 3.9e-31 107.7 0.0 4.8e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBY31289.1 - 3.7e-27 95.1 0.0 4.3e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 CBY31289.1 - 0.052 13.3 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain IPT PF01745.16 CBY31289.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Isopentenyl transferase G5 PF07501.12 CBY31289.1 - 0.18 12.3 0.1 1.8 9.0 0.0 2.0 2 0 0 2 2 2 0 G5 domain Glycos_transf_2 PF00535.26 CBY31290.1 - 9.4e-28 97.1 0.0 1.6e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY31290.1 - 5.8e-16 58.9 2.0 1.4e-15 57.7 2.0 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.6 CBY31290.1 - 4.3e-06 26.8 0.0 2.8e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY31290.1 - 0.00044 19.9 0.1 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY31290.1 - 0.0049 16.4 0.0 0.026 14.0 0.0 2.1 2 1 1 3 3 3 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.22 CBY31291.1 - 3.8e-17 62.7 0.9 5.6e-17 62.2 0.9 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CBY31291.1 - 0.042 14.6 0.1 3.1 8.6 0.1 2.9 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Glycos_transf_2 PF00535.26 CBY31292.1 - 2.9e-14 53.2 0.0 5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 TssO PF17561.2 CBY31292.1 - 0.0068 16.5 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Type VI secretion system, TssO OAD_gamma PF04277.13 CBY31292.1 - 0.13 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GCIP PF13324.6 CBY31293.1 - 0.066 12.8 2.7 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF3446 PF11928.8 CBY31293.1 - 7.8 6.9 11.7 1.9 8.9 6.0 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain SGL PF08450.12 CBY31294.1 - 0.031 13.9 0.0 1.6 8.2 0.0 2.4 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 CBY31294.1 - 0.036 14.1 1.2 1.5 9.0 0.0 3.7 4 0 0 4 4 4 0 NHL repeat Pkinase PF00069.25 CBY31296.1 - 1.4e-32 113.1 0.0 6.1e-32 111.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31296.1 - 6.9e-13 48.5 0.0 8.5e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 CBY31296.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 CAAD PF14159.6 CBY31296.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Pkinase PF00069.25 CBY31298.1 - 4.8e-65 219.5 1.5 9.6e-65 218.6 1.5 1.5 1 0 0 1 1 1 1 Protein kinase domain RCC1 PF00415.18 CBY31298.1 - 8.2e-46 154.4 2.3 6.5e-12 45.9 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 CBY31298.1 - 1.5e-40 139.2 0.3 2.9e-40 138.2 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 CBY31298.1 - 1.1e-22 79.3 14.4 5.8e-09 35.5 0.3 5.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kinase-like PF14531.6 CBY31298.1 - 1.5e-07 31.0 0.0 3.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY31298.1 - 0.00021 20.7 0.6 0.00042 19.7 0.6 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY31298.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase CHIPS PF11434.8 CBY31298.1 - 0.035 13.9 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS APH PF01636.23 CBY31298.1 - 0.24 11.3 3.2 10 5.9 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 CBY31299.1 - 4.7e-05 23.4 12.7 8.7e-05 22.6 12.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY31299.1 - 0.00084 19.4 11.1 0.0026 17.8 11.1 1.9 1 0 0 1 1 1 1 Basic region leucine zipper TMEM52 PF14979.6 CBY31299.1 - 0.14 12.0 0.2 0.32 10.9 0.2 1.6 1 0 0 1 1 1 0 Transmembrane 52 bZIP_Maf PF03131.17 CBY31299.1 - 0.22 12.0 11.5 0.07 13.7 7.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF5045 PF16464.5 CBY31299.1 - 0.26 11.6 2.8 0.58 10.5 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) TMCO5 PF14992.6 CBY31299.1 - 1.1 8.8 12.1 0.17 11.5 8.4 1.4 2 0 0 2 2 2 0 TMCO5 family Uso1_p115_C PF04871.13 CBY31299.1 - 7 7.0 12.7 0.52 10.7 6.7 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CDO_I PF05995.12 CBY31300.1 - 4e-30 104.3 0.0 5e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY31300.1 - 0.081 12.4 0.0 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 PCO_ADO CAML PF14963.6 CBY31301.1 - 0.12 12.5 2.2 0.19 11.8 2.2 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand YL1 PF05764.13 CBY31301.1 - 2.7 8.0 12.4 4.1 7.4 12.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TEX15 PF15326.6 CBY31301.1 - 4.1 7.1 6.8 6.2 6.5 6.8 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 FSA_C PF10479.9 CBY31301.1 - 4.9 5.2 20.4 6.4 4.8 20.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 CBY31301.1 - 5.2 5.5 9.9 5.4 5.4 9.9 1.1 1 0 0 1 1 1 0 Macoilin family cEGF PF12662.7 CBY31302.1 - 2.7e-05 24.0 18.0 0.2 11.6 0.1 4.6 3 0 0 3 3 3 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY31302.1 - 9.5 6.6 27.1 3.1 8.2 1.1 4.8 4 1 0 4 4 4 0 Coagulation Factor Xa inhibitory site Na_Ca_ex PF01699.24 CBY31303.1 - 1.6e-15 57.3 14.6 1.6e-15 57.3 14.6 1.9 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 CBY31304.1 - 8.2e-15 55.1 12.5 1.1e-14 54.6 12.5 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Vps23_core PF09454.10 CBY31305.1 - 0.24 11.4 1.1 1.4 8.9 0.3 2.6 2 0 0 2 2 2 0 Vps23 core domain Ank_2 PF12796.7 CBY31307.1 - 2.2e-31 108.3 0.0 3.3e-14 53.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY31307.1 - 3.7e-27 94.3 0.8 8.2e-11 42.2 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 CBY31307.1 - 1.2e-25 90.2 14.4 1.2e-25 90.2 14.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 CBY31307.1 - 4.6e-25 87.3 1.4 9.4e-08 32.2 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY31307.1 - 8.9e-25 86.0 0.1 0.00011 22.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY31307.1 - 4.3e-21 72.7 0.2 0.00078 19.7 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat MARVEL PF01284.23 CBY31307.1 - 0.0038 17.2 2.6 0.099 12.7 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain 7TM_GPCR_Srd PF10317.9 CBY31307.1 - 0.51 9.5 8.0 0.088 12.0 3.8 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd PID PF00640.23 CBY31309.1 - 3.6e-05 23.8 0.1 0.0001 22.4 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Gly-zipper_OmpA PF13436.6 CBY31309.1 - 1.2 8.9 6.3 3.1 7.7 6.3 1.6 1 0 0 1 1 1 0 Glycine-zipper domain Anticodon_1 PF08264.13 CBY31310.1 - 5.3e-30 104.4 0.1 9.8e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 CBY31310.1 - 5.1e-06 25.0 0.0 7.8e-06 24.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBY31310.1 - 0.043 12.6 0.0 0.087 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (M) RNase_T PF00929.24 CBY31310.1 - 0.12 12.9 0.1 7.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Exonuclease Lectin_C PF00059.21 CBY31313.1 - 0.00034 21.3 2.7 0.0013 19.4 2.7 2.1 1 1 0 1 1 1 1 Lectin C-type domain Syndecan PF01034.20 CBY31313.1 - 0.007 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain DUF5305 PF17231.2 CBY31313.1 - 0.059 12.8 0.1 0.059 12.8 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) TMEM154 PF15102.6 CBY31313.1 - 2.5 8.0 7.5 12 5.8 7.5 1.9 1 1 0 1 1 1 0 TMEM154 protein family CAP_GLY PF01302.25 CBY31314.1 - 2.9e-12 46.4 0.1 4.8e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CCDC106 PF15794.5 CBY31314.1 - 7.1 6.3 15.3 6.1 6.5 7.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TFIIA PF03153.13 CBY31315.1 - 0.014 15.4 25.1 0.019 15.0 25.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 CBY31315.1 - 3.3 7.4 10.4 0.11 12.3 3.7 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 CBY31315.1 - 4.1 6.2 4.6 4.8 6.0 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Selenoprotein_S PF06936.11 CBY31315.1 - 4.2 7.1 16.6 10 5.9 11.4 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) Agouti PF05039.12 CBY31315.1 - 4.7 8.0 14.3 0.61 10.8 9.7 1.8 2 0 0 2 2 2 0 Agouti protein Hydrolase PF00702.26 CBY31316.1 - 0.00013 22.4 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Atg31 PF09795.9 CBY31316.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 31 2OG-FeII_Oxy PF03171.20 CBY31317.1 - 6.5e-19 68.3 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY31317.1 - 2.5e-09 37.9 0.8 9.8e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal VWC PF00093.18 CBY31318.1 - 0.043 14.1 0.3 0.043 14.1 0.3 6.9 4 2 1 5 5 5 0 von Willebrand factor type C domain CBP_BcsG PF11658.8 CBY31318.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PTR2 PF00854.21 CBY31319.1 - 5.3e-91 305.4 11.3 2.9e-79 266.7 6.2 2.3 2 0 0 2 2 2 2 POT family DUF4452 PF14618.6 CBY31319.1 - 0.16 11.8 2.1 0.31 10.9 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DLH PF01738.18 CBY31320.1 - 1.8e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Gamma-thionin PF00304.20 CBY31320.1 - 6.2 7.2 7.4 2 8.7 0.8 2.3 2 0 0 2 2 2 0 Gamma-thionin family MFS_1 PF07690.16 CBY31321.1 - 1.1e-39 136.3 21.4 7.1e-39 133.7 19.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MbeD_MobD PF04899.12 CBY31322.1 - 0.3 11.2 2.7 0.84 9.8 2.7 1.7 1 0 0 1 1 1 0 MbeD/MobD like DUF3456 PF11938.8 CBY31323.1 - 3.5e-10 40.6 5.0 0.00035 21.1 2.2 2.1 1 1 1 2 2 2 2 TLR4 regulator and MIR-interacting MSAP VSP PF03302.13 CBY31324.1 - 0.00071 18.5 11.1 0.00076 18.4 11.1 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein Laminin_EGF PF00053.24 CBY31324.1 - 1.7 8.8 23.5 0.2 11.8 10.1 2.6 1 1 1 2 2 2 0 Laminin EGF domain SH3_2 PF07653.17 CBY31325.1 - 7.5e-06 25.5 0.1 0.058 13.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY31325.1 - 2.1e-05 24.0 0.1 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY31325.1 - 3.6e-05 23.5 0.0 0.041 13.8 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain hSH3 PF14603.6 CBY31325.1 - 0.028 14.9 0.5 1.4 9.4 0.1 2.6 1 1 1 2 2 2 0 Helically-extended SH3 domain SLATT_5 PF18160.1 CBY31326.1 - 0.0011 18.4 0.4 0.002 17.5 0.4 1.4 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 Tweety PF04906.13 CBY31326.1 - 0.003 16.3 0.0 0.0038 16.0 0.0 1.1 1 0 0 1 1 1 1 Tweety DUF2207 PF09972.9 CBY31326.1 - 0.0033 16.3 0.1 0.0042 15.9 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Syndecan PF01034.20 CBY31326.1 - 0.0049 16.8 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain FAD_SOX PF18371.1 CBY31326.1 - 0.1 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase ACCA PF03255.14 CBY31326.1 - 0.14 12.0 2.1 0.84 9.5 0.2 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TSC22 PF01166.18 CBY31326.1 - 0.18 12.1 2.7 0.39 11.1 2.7 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family MinE PF03776.14 CBY31326.1 - 2.1 8.4 6.9 8.1 6.5 4.5 2.5 1 1 2 3 3 3 0 Septum formation topological specificity factor MinE Zona_pellucida PF00100.23 CBY31327.1 - 3.1e-24 86.2 0.1 3.1e-24 86.2 0.1 1.3 2 0 0 2 2 2 1 Zona pellucida-like domain DUF3439 PF11921.8 CBY31327.1 - 0.0056 16.6 0.6 0.011 15.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Zona_pellucida PF00100.23 CBY31328.1 - 4e-07 30.1 2.0 6.4e-07 29.4 2.0 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain UPF0228 PF05727.11 CBY31328.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0228) Fer4_7 PF12838.7 CBY31328.1 - 7.6 7.2 11.7 0.52 10.9 5.8 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain C5-epim_C PF06662.13 CBY31329.1 - 1.6e-54 184.3 0.0 2.6e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus SLC3A2_N PF16028.5 CBY31330.1 - 3.7e-28 96.9 0.1 6.1e-28 96.2 0.1 1.3 1 0 0 1 1 1 1 Solute carrier family 3 member 2 N-terminus GTP_EFTU PF00009.27 CBY31330.1 - 0.061 12.9 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain p450 PF00067.22 CBY31331.1 - 5.7e-92 308.9 0.1 7.2e-92 308.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 C1_2 PF03107.16 CBY31332.1 - 0.047 14.0 1.5 0.047 14.0 1.5 1.9 2 0 0 2 2 2 0 C1 domain DUF3878 PF12994.7 CBY31332.1 - 0.082 12.3 0.3 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) VATC PF18716.1 CBY31332.1 - 0.11 12.4 4.1 0.23 11.3 4.1 1.6 1 0 0 1 1 1 0 Vms1-associating treble clef domain zinc_ribbon_2 PF13240.6 CBY31332.1 - 0.14 11.9 1.0 0.34 10.7 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-FCS PF06467.14 CBY31332.1 - 0.2 11.6 8.0 2.1 8.3 8.0 2.3 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif YhfH PF14149.6 CBY31332.1 - 0.45 10.5 4.9 0.92 9.5 4.9 1.5 1 0 0 1 1 1 0 YhfH-like protein YyzF PF14116.6 CBY31332.1 - 0.47 10.5 3.0 0.35 10.9 0.8 1.9 2 0 0 2 2 2 0 YyzF-like protein DUF2116 PF09889.9 CBY31332.1 - 8.8 6.4 9.7 1.1 9.4 1.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) AAA_12 PF13087.6 CBY31333.1 - 7.2e-46 156.3 0.7 7.2e-46 156.3 0.7 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 CBY31333.1 - 2.2e-20 73.6 13.2 9.4e-20 71.5 6.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY31333.1 - 2.2e-08 34.5 0.0 2.3e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY31333.1 - 6e-07 29.4 0.0 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBY31333.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 CBY31333.1 - 0.0079 16.6 0.0 0.027 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY31333.1 - 0.0083 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY31333.1 - 0.013 15.7 0.0 0.094 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY31333.1 - 0.015 15.3 0.0 0.052 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 CBY31333.1 - 0.021 14.8 0.0 0.021 14.8 0.0 3.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CBY31333.1 - 0.029 13.8 0.0 0.079 12.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 CBY31333.1 - 0.054 13.7 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CBY31333.1 - 0.063 13.0 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 CBY31333.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Eco57I PF07669.11 CBY31333.1 - 0.41 11.2 2.3 0.96 10.0 1.0 2.4 2 0 0 2 2 1 0 Eco57I restriction-modification methylase FoP_duplication PF13865.6 CBY31334.1 - 0.28 11.7 10.8 0.41 11.2 10.8 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 F-box-like PF12937.7 CBY31336.1 - 7.5e-08 32.2 0.1 1.4e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY31336.1 - 0.00013 21.8 4.6 0.0019 18.1 4.6 2.4 1 1 0 1 1 1 1 F-box domain Sulfotransfer_1 PF00685.27 CBY31337.1 - 9.7e-16 58.0 0.0 2.4e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31337.1 - 7.5e-07 29.8 0.1 0.61 10.4 0.0 3.7 2 1 2 4 4 4 3 Sulfotransferase family DUF1103 PF06513.11 CBY31337.1 - 0.058 13.0 0.6 0.096 12.3 0.6 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) adh_short PF00106.25 CBY31338.1 - 1.2e-47 161.9 1.2 1.5e-47 161.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY31338.1 - 2.2e-35 122.3 0.5 2.7e-35 122.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY31338.1 - 2.3e-09 37.4 0.5 3.7e-09 36.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY31338.1 - 0.054 13.0 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family C2 PF00168.30 CBY31340.1 - 4.5e-48 161.8 0.2 3.7e-23 81.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.6 CBY31340.1 - 0.0041 16.7 0.0 0.014 15.0 0.0 1.9 1 0 0 1 1 1 1 CEP76 C2 domain DUF3137 PF11335.8 CBY31340.1 - 0.014 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Ctr PF04145.15 CBY31341.1 - 6.5e-20 72.2 12.2 2.6e-18 67.0 9.5 2.4 1 1 1 2 2 2 1 Ctr copper transporter family AA_permease_C PF13906.6 CBY31341.1 - 0.48 10.5 4.1 0.86 9.7 4.1 1.5 1 0 0 1 1 1 0 C-terminus of AA_permease DUF3487 PF11990.8 CBY31341.1 - 2.6 8.0 5.3 18 5.2 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Choline_kinase PF01633.20 CBY31342.1 - 2.5e-08 33.8 0.3 3.7e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY31342.1 - 5e-05 22.8 0.1 7.7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase SdrG_C_C PF10425.9 CBY31342.1 - 0.027 14.6 0.9 0.088 12.9 0.1 2.0 2 0 0 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin DUF2252 PF10009.9 CBY31342.1 - 0.065 12.3 0.0 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF1679 PF07914.11 CBY31342.1 - 0.077 11.8 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Connexin PF00029.19 CBY31343.1 - 2.1e-35 122.6 2.6 2.7e-35 122.2 2.6 1.1 1 0 0 1 1 1 1 Connexin Cyc-maltodext_C PF10438.9 CBY31343.1 - 0.095 12.8 0.3 0.24 11.5 0.3 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Integrin_alpha2 PF08441.12 CBY31344.1 - 3e-44 151.7 2.0 5.2e-44 150.9 2.0 1.4 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY31344.1 - 4.7e-14 52.2 23.7 9e-08 32.1 7.1 5.1 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 CBY31344.1 - 2.1e-11 44.2 2.8 4.8e-05 23.9 0.1 3.5 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.18 CBY31344.1 - 0.15 12.3 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 FG-GAP_2 PF14312.6 CBY31344.1 - 1.1 9.6 15.0 2.3 8.6 0.3 4.4 4 0 0 4 4 4 0 FG-GAP repeat DUF2724 PF10893.8 CBY31346.1 - 0.12 12.2 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) TMPIT PF07851.13 CBY31346.1 - 2.2 7.5 6.2 3 7.0 6.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein CUB PF00431.20 CBY31347.1 - 1.5e-28 99.3 6.1 1.9e-14 53.9 0.1 4.4 4 0 0 4 4 4 4 CUB domain CUB PF00431.20 CBY31348.1 - 2.3e-16 60.1 0.5 3.9e-13 49.7 0.0 2.9 3 0 0 3 3 3 2 CUB domain Glycolytic PF00274.19 CBY31350.1 - 2.4e-111 371.9 0.0 2.6e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I FeoB_associated PF12669.7 CBY31352.1 - 0.0085 16.5 3.2 0.013 15.9 3.2 1.2 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein ARF7EP_C PF14949.6 CBY31352.1 - 0.012 16.3 3.8 0.016 15.8 3.8 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus ITI_HC_C PF06668.12 CBY31353.1 - 9.3e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Gp_dh_C PF02800.20 CBY31354.1 - 1.8e-59 199.8 0.5 2.6e-59 199.3 0.5 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY31354.1 - 1.3e-33 115.4 0.0 3.4e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY31354.1 - 0.0012 18.9 2.6 0.025 14.7 0.3 3.3 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 CBY31354.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACT_4 PF13291.6 CBY31354.1 - 0.12 12.9 0.2 0.34 11.5 0.0 1.9 2 0 0 2 2 2 0 ACT domain DUF3042 PF11240.8 CBY31355.1 - 0.036 14.1 1.0 0.071 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF3149 PF11346.8 CBY31355.1 - 0.11 12.2 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Trypsin PF00089.26 CBY31356.1 - 6e-44 150.5 0.8 6.7e-44 150.3 0.8 1.0 1 0 0 1 1 1 1 Trypsin TNV_CP PF03898.13 CBY31356.1 - 0.011 15.0 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein DUF316 PF03761.15 CBY31356.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 LpoB PF13036.6 CBY31356.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB MAP65_ASE1 PF03999.12 CBY31357.1 - 0.36 9.5 3.4 0.42 9.2 3.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Somatomedin_B PF01033.17 CBY31357.1 - 1.1 9.7 24.4 0.98 9.9 23.1 1.7 1 1 0 1 1 1 0 Somatomedin B domain FSA_C PF10479.9 CBY31357.1 - 3.8 5.5 18.1 4.5 5.3 18.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SprA-related PF12118.8 CBY31357.1 - 9.2 5.3 13.3 11 5.0 13.3 1.1 1 0 0 1 1 1 0 SprA-related family P2_N PF18628.1 CBY31358.1 - 0.047 13.4 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain Asp PF00026.23 CBY31359.1 - 2.2e-96 323.0 0.0 2.6e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY31359.1 - 2.2e-11 44.3 0.1 4.6e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CBY31359.1 - 7.9e-05 22.5 0.0 0.00026 20.8 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MtrF PF09472.10 CBY31359.1 - 0.081 12.3 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Pkinase_Tyr PF07714.17 CBY31360.1 - 2.8e-18 66.1 0.1 7.5e-17 61.5 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY31360.1 - 3e-07 30.1 0.2 9.8e-07 28.4 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.6 CBY31361.1 - 1.2e-10 41.6 7.8 1.7e-10 41.0 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBY31361.1 - 6.9e-10 38.5 3.6 1.3e-09 37.6 3.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY31361.1 - 2.2e-06 27.5 8.2 3.2e-06 27.0 8.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY31361.1 - 5.7e-05 23.3 8.0 0.00057 20.1 8.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY31361.1 - 8e-05 22.4 9.6 0.00012 21.8 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY31361.1 - 8.5e-05 22.5 2.5 8.5e-05 22.5 2.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY31361.1 - 0.00017 21.3 8.1 0.0003 20.6 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY31361.1 - 0.0025 17.7 3.4 0.0051 16.7 3.4 1.5 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY31361.1 - 0.0056 16.5 8.3 0.0095 15.8 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY31361.1 - 0.0075 16.1 7.2 0.011 15.6 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBY31361.1 - 0.017 15.1 1.4 0.019 14.9 1.4 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.8 CBY31361.1 - 0.025 14.4 4.5 0.042 13.7 4.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.22 CBY31361.1 - 0.11 12.4 5.4 0.079 12.9 3.8 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 CBY31361.1 - 0.15 12.1 4.9 0.38 10.8 4.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 CBY31361.1 - 0.19 11.7 6.6 1.5 8.8 6.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CBY31361.1 - 0.29 11.2 4.8 0.53 10.4 4.8 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 CBY31361.1 - 0.3 11.0 8.0 1.1 9.2 8.0 1.9 1 1 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CBY31361.1 - 1.1 8.9 7.4 2.9 7.6 7.4 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Phospholip_A2_1 PF00068.19 CBY31362.1 - 2.3e-13 50.6 8.6 4.5e-13 49.7 8.6 1.5 1 0 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.23 CBY31363.1 - 4e-44 150.6 0.2 5.2e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY31363.1 - 4.8e-23 82.5 2.8 8.2e-23 81.7 2.8 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY31364.1 - 4e-44 150.6 0.2 5.2e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY31364.1 - 1.9e-23 83.8 1.7 2.6e-23 83.3 1.7 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Bacillus_HBL PF05791.11 CBY31365.1 - 0.00022 21.1 4.6 0.0014 18.5 0.6 2.0 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 CBY31365.1 - 0.00084 18.3 18.2 0.00098 18.1 18.2 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein FapA PF03961.13 CBY31365.1 - 0.03 13.0 11.9 0.033 12.8 11.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FmiP_Thoc5 PF09766.9 CBY31365.1 - 0.037 13.3 13.0 0.042 13.1 13.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 CBY31365.1 - 0.041 13.9 10.1 0.14 12.2 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HemX PF04375.14 CBY31365.1 - 0.051 12.9 10.7 0.055 12.7 10.7 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Seryl_tRNA_N PF02403.22 CBY31365.1 - 0.055 13.7 14.5 0.084 13.1 14.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 CBY31365.1 - 0.26 12.5 17.0 0.61 11.3 16.7 1.7 1 1 0 1 1 1 0 Protein SOGA TMPIT PF07851.13 CBY31365.1 - 0.48 9.6 12.4 0.53 9.5 12.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 CBY31365.1 - 0.53 9.6 12.1 0.63 9.3 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WDCP PF15390.6 CBY31365.1 - 0.89 7.9 7.4 1 7.6 7.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Med30 PF11315.8 CBY31365.1 - 0.9 9.7 13.2 1.8 8.7 9.6 1.9 1 1 1 2 2 2 0 Mediator complex subunit 30 GAS PF13851.6 CBY31365.1 - 1.1 8.5 21.9 2.1 7.7 21.9 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 CBY31365.1 - 1.2 9.7 4.8 21 5.7 4.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 CBY31365.1 - 1.7 8.2 10.8 1.8 8.1 10.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 CBY31365.1 - 1.7 9.3 20.8 1.3e+02 3.3 20.8 2.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1515 PF07439.11 CBY31365.1 - 2.5 8.2 6.6 5.9 7.0 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 CBY31365.1 - 3 7.1 11.4 3.9 6.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CBY31365.1 - 6.1 7.4 26.0 56 4.3 26.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 CBY31365.1 - 9.5 6.9 12.5 8.3 7.1 9.9 1.9 1 1 1 2 2 2 0 Initiation control protein YabA GAS PF13851.6 CBY31366.1 - 0.0025 17.2 7.9 0.0025 17.2 7.9 20.6 3 1 14 19 19 19 6 Growth-arrest specific micro-tubule binding HypA PF01155.19 CBY31366.1 - 0.011 15.7 0.4 0.42 10.6 0.2 3.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 CBY31367.1 - 8.9e-79 265.4 17.6 1.2e-78 265.0 17.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY31367.1 - 3.1e-16 59.3 25.4 1.6e-12 47.0 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.13 CBY31367.1 - 0.043 13.3 0.3 0.076 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) EGF_CA PF07645.15 CBY31368.1 - 8.2e-143 464.4 448.3 9.7e-10 38.5 8.6 30.6 24 7 6 30 30 30 25 Calcium-binding EGF domain EGF_3 PF12947.7 CBY31368.1 - 5.1e-80 263.3 379.4 4.4e-09 36.4 10.9 30.7 26 4 4 30 30 30 25 EGF domain cEGF PF12662.7 CBY31368.1 - 9.9e-61 201.2 289.1 5.5e-05 23.0 5.6 29.9 30 2 0 30 30 30 23 Complement Clr-like EGF-like EGF PF00008.27 CBY31368.1 - 6.2e-20 71.2 376.1 0.00036 20.8 3.4 31.0 29 2 1 30 30 30 19 EGF-like domain FXa_inhibition PF14670.6 CBY31368.1 - 5.8e-16 58.5 362.2 0.00016 21.8 2.4 29.5 20 6 9 29 29 29 16 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY31368.1 - 1.1e-13 51.3 326.3 0.0041 17.7 1.3 33.1 32 0 0 32 32 32 19 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY31368.1 - 0.00036 20.5 14.8 0.00091 19.2 7.7 28.5 26 3 3 29 29 29 13 MSP1 EGF domain 1 PYNP_C PF07831.13 CBY31370.1 - 0.0064 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain zf-C2HE PF16278.5 CBY31370.1 - 0.0089 16.5 1.5 0.012 16.0 0.3 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger RNase_T PF00929.24 CBY31370.1 - 0.035 14.7 0.2 0.059 13.9 0.1 1.7 1 1 0 1 1 1 0 Exonuclease TIR_2 PF13676.6 CBY31370.1 - 0.077 13.6 0.1 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 TIR domain zf-C2H2_4 PF13894.6 CBY31370.1 - 0.14 13.1 2.9 0.42 11.6 2.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY31370.1 - 4.1 8.0 6.0 3 8.4 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Forkhead PF00250.18 CBY31371.1 - 1.6e-37 127.7 0.0 2.6e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain AAA PF00004.29 CBY31373.1 - 0.03 14.8 1.6 0.49 10.8 0.3 2.5 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) C2 PF00168.30 CBY31374.1 - 1.5e-47 160.1 0.1 4e-19 68.8 0.0 3.4 3 0 0 3 3 3 3 C2 domain CEP76-C2 PF15627.6 CBY31374.1 - 8.5e-08 31.9 0.1 0.0038 16.8 0.0 3.2 3 0 0 3 3 3 2 CEP76 C2 domain Reticulon PF02453.17 CBY31374.1 - 0.0076 16.2 1.4 0.016 15.2 1.4 1.5 1 0 0 1 1 1 1 Reticulon DUF4094 PF13334.6 CBY31374.1 - 0.049 14.0 0.1 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Pex24p PF06398.11 CBY31374.1 - 0.087 11.8 3.7 0.089 11.8 2.3 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PAX PF00292.18 CBY31375.1 - 4.6e-66 220.4 0.8 6.6e-66 219.9 0.8 1.2 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY31375.1 - 8.8e-24 83.1 6.4 1.4e-23 82.4 6.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY31375.1 - 8.7e-05 22.3 0.8 8.7e-05 22.3 0.8 2.3 3 0 0 3 3 3 1 Homeobox KN domain HTH_23 PF13384.6 CBY31375.1 - 0.00038 20.2 1.0 0.0046 16.7 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CBY31375.1 - 0.0057 16.7 0.1 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 CBY31375.1 - 0.17 12.0 0.6 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TLP-20 PF06088.11 CBY31375.1 - 0.23 11.4 2.0 0.33 10.8 2.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4533 PF15047.6 CBY31375.1 - 0.49 9.9 2.0 0.77 9.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) CDC45 PF02724.14 CBY31375.1 - 1.1 7.4 6.0 1.5 7.0 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA_bind_2 PF13725.6 CBY31375.1 - 1.8 8.2 3.9 2.9 7.5 3.9 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain FAM176 PF14851.6 CBY31375.1 - 3.1 7.4 5.8 5.9 6.5 5.8 1.5 1 0 0 1 1 1 0 FAM176 family EGF PF00008.27 CBY31376.1 - 3.7e-15 55.9 30.9 7.6e-07 29.3 7.3 3.6 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 CBY31376.1 - 1.1e-07 32.2 22.8 0.0013 19.3 4.4 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY31376.1 - 3.7e-05 24.0 40.3 0.0016 18.7 12.6 3.4 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 CBY31376.1 - 0.014 15.6 31.2 0.094 12.9 5.5 3.7 4 0 0 4 4 4 0 EGF domain Laminin_EGF PF00053.24 CBY31376.1 - 0.12 12.5 28.8 1.8 8.8 11.0 3.5 1 1 2 3 3 3 0 Laminin EGF domain EGF_CA PF07645.15 CBY31376.1 - 0.16 12.2 32.2 2 8.7 5.5 3.4 2 1 1 3 3 3 0 Calcium-binding EGF domain Sulfotransfer_1 PF00685.27 CBY31379.1 - 5.9e-26 91.5 0.1 7.8e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31379.1 - 1.4e-13 51.7 0.1 4.3e-09 37.1 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY31379.1 - 0.00016 21.7 0.5 0.00041 20.3 0.5 1.8 1 1 0 1 1 1 1 Sulfotransferase family Laminin_G_1 PF00054.23 CBY31380.1 - 0.00029 21.0 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CBY31380.1 - 0.0041 17.7 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain Trypsin PF00089.26 CBY31381.1 - 7.1e-57 192.7 1.5 1.9e-56 191.3 1.5 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY31381.1 - 0.00056 20.8 0.0 0.0013 19.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY31381.1 - 0.00094 19.6 0.1 0.002 18.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) DUF4793 PF16041.5 CBY31381.1 - 0.31 11.2 3.4 1.5 9.0 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4793) TMEM164 PF14808.6 CBY31382.1 - 5.9e-86 287.9 7.9 6.8e-86 287.7 7.9 1.0 1 0 0 1 1 1 1 TMEM164 family Collagen PF01391.18 CBY31383.1 - 1.6e-168 546.6 695.5 1.7e-08 34.1 37.3 21.5 1 1 11 12 12 12 11 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY31383.1 - 9.5e-77 257.4 0.3 1.3e-76 257.0 0.3 1.1 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain VWC PF00093.18 CBY31383.1 - 3.6e-09 36.8 14.9 3.6e-09 36.8 14.9 1.6 2 0 0 2 2 2 1 von Willebrand factor type C domain Tmem26 PF09772.9 CBY31384.1 - 6.5e-75 252.2 1.4 4.8e-52 177.1 0.3 2.2 2 0 0 2 2 2 2 Transmembrane protein 26 MAP1B_neuraxin PF00414.17 CBY31384.1 - 0.12 12.0 0.2 0.25 10.9 0.2 1.6 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat PMP22_Claudin PF00822.20 CBY31386.1 - 8.2e-08 32.3 5.8 3.1e-07 30.4 5.8 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY31386.1 - 0.00015 21.6 3.9 0.0026 17.5 3.9 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.12 CBY31386.1 - 0.012 15.3 1.2 0.012 15.3 1.2 1.8 1 1 0 2 2 2 0 SUR7/PalI family Prefoldin_2 PF01920.20 CBY31387.1 - 4.2e-19 68.5 3.9 4.8e-19 68.3 3.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 CBY31387.1 - 0.0034 17.9 0.3 0.08 13.6 0.0 2.1 2 0 0 2 2 2 1 SlyX HBM PF16591.5 CBY31387.1 - 0.025 14.0 0.1 0.045 13.2 0.0 1.5 1 1 0 1 1 1 0 Helical bimodular sensor domain SesA PF17107.5 CBY31387.1 - 0.026 14.7 0.3 0.033 14.4 0.3 1.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CCDC-167 PF15188.6 CBY31387.1 - 0.086 13.2 2.1 1.1 9.6 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 CBY31387.1 - 1.7 9.1 6.6 7.4 7.1 0.5 2.2 2 0 0 2 2 2 0 Cell division protein ZapB InaF-motif PF15018.6 CBY31388.1 - 1.1e-11 44.4 3.8 2.2e-11 43.4 3.8 1.6 1 0 0 1 1 1 1 TRP-interacting helix PH PF00169.29 CBY31388.1 - 5.4e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CBY31388.1 - 0.024 15.1 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Myotub-related PF06602.14 CBY31389.1 - 4.4e-14 52.2 0.0 4.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain VQ PF05678.14 CBY31389.1 - 0.082 12.4 0.0 4.4 6.9 0.0 2.6 2 0 0 2 2 2 0 VQ motif Myotub-related PF06602.14 CBY31390.1 - 9.6e-18 64.2 0.2 2.2e-17 63.1 0.2 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CBY31390.1 - 2.4e-12 46.7 0.0 4.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DENN PF02141.21 CBY31391.1 - 5.7e-32 111.2 0.0 9.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CBY31391.1 - 0.0058 16.6 2.0 0.011 15.6 2.0 1.5 1 0 0 1 1 1 1 dDENN domain Acetyltransf_1 PF00583.25 CBY31392.1 - 0.0015 18.8 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY31392.1 - 0.0096 15.9 0.0 0.05 13.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY31392.1 - 0.033 14.2 0.0 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY31392.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LTXXQ PF07813.12 CBY31393.1 - 0.00047 20.8 11.0 0.00047 20.8 11.0 2.3 2 1 1 3 3 3 1 LTXXQ motif family protein V_ATPase_I PF01496.19 CBY31393.1 - 0.66 7.8 12.6 0.77 7.6 12.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1974 PF09317.11 CBY31393.1 - 3.2 7.3 9.4 4.5 6.7 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) PP2C PF00481.21 CBY31394.1 - 2e-68 230.8 0.1 2.8e-68 230.4 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY31394.1 - 5.7e-06 26.1 0.0 3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_C PF07830.13 CBY31394.1 - 0.00029 21.2 0.0 0.0009 19.7 0.0 1.9 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain SIR2 PF02146.17 CBY31395.1 - 1.2e-58 198.0 0.0 2e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CBY31395.1 - 0.0015 18.3 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 CBY31395.1 - 0.047 13.5 0.2 0.091 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Pox_D5 PF03288.16 CBY31396.1 - 0.22 12.1 1.9 1.7 9.2 1.9 2.0 1 1 0 1 1 1 0 Poxvirus D5 protein-like Metallophos PF00149.28 CBY31397.1 - 2.7e-41 142.3 0.0 3.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY31397.1 - 2.4e-22 79.1 0.5 4.8e-22 78.1 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TRIQK PF15168.6 CBY31399.1 - 6.1e-36 122.2 0.0 6.5e-36 122.1 0.0 1.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family Ureide_permease PF07168.11 CBY31399.1 - 0.059 12.1 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Ureide permease Orf78 PF06024.12 CBY31399.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) WH1 PF00568.23 CBY31400.1 - 5.6e-19 68.1 0.0 9.5e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CBY31400.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 WH2 motif ABC_membrane PF00664.23 CBY31401.1 - 8.2e-07 28.9 6.7 5.6e-05 22.9 6.7 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region Sbt_1 PF05982.12 CBY31401.1 - 0.03 13.6 0.2 0.04 13.2 0.2 1.1 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily Acyl_transf_3 PF01757.22 CBY31402.1 - 1.4e-05 24.4 3.9 1.7e-05 24.1 3.9 1.0 1 0 0 1 1 1 1 Acyltransferase family Anti-TRAP PF15777.5 CBY31404.1 - 0.15 12.0 0.5 0.15 12.0 0.5 2.3 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MCR PF18509.1 CBY31404.1 - 0.76 9.4 0.1 0.76 9.4 0.1 3.2 3 0 0 3 3 3 0 Magnetochrome domain zinc_ribbon_4 PF13717.6 CBY31404.1 - 4 7.4 10.8 1.2 9.1 0.5 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CBY31404.1 - 4.2 7.4 14.1 0.34 10.9 5.9 2.8 3 1 0 3 3 3 0 SprT-like zinc ribbon domain HypA PF01155.19 CBY31404.1 - 5 7.2 7.2 3 7.9 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2963 PF11178.8 CBY31410.1 - 0.026 14.2 1.7 0.096 12.4 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) SGL PF08450.12 CBY31410.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF4821 PF16092.5 CBY31411.1 - 2.9e-20 73.0 0.8 1.7e-19 70.5 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) DUF4821 PF16092.5 CBY31413.1 - 1.7e-06 27.9 0.3 8.4e-06 25.6 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 CBY31414.1 - 3.3e-07 29.8 0.2 0.0093 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAC PF01849.18 CBY31414.1 - 0.081 12.9 1.1 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 NAC domain SMC_ScpB PF04079.16 CBY31414.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Pou PF00157.17 CBY31415.1 - 1.3e-36 124.4 0.6 2.8e-36 123.3 0.1 1.9 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY31415.1 - 1.2e-16 60.3 2.4 5.2e-16 58.2 2.4 2.2 1 0 0 1 1 1 1 Homeodomain DASH_Dam1 PF08653.10 CBY31415.1 - 0.12 12.2 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 Pro_CA PF00484.19 CBY31415.1 - 3.4 7.9 5.1 24 5.2 0.1 2.3 2 0 0 2 2 2 0 Carbonic anhydrase MOLO1 PF17175.4 CBY31415.1 - 3.8 7.7 6.8 1 9.5 2.4 2.1 2 1 0 2 2 2 0 Modulator of levamisole receptor-1 GPW_gp25 PF04965.14 CBY31416.1 - 0.035 13.9 0.1 0.14 12.0 0.0 2.0 3 0 0 3 3 3 0 Gene 25-like lysozyme Siva PF05458.12 CBY31416.1 - 0.077 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CCDC71L PF15374.6 CBY31416.1 - 0.4 9.9 5.9 1 8.5 6.0 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L DUF2149 PF09919.9 CBY31416.1 - 2.8 8.2 4.5 14 6.1 4.5 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) PQQ_2 PF13360.6 CBY31417.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain SICA_beta PF12878.7 CBY31417.1 - 0.83 9.8 9.9 1.5 9.0 9.9 1.4 1 0 0 1 1 1 0 SICA extracellular beta domain LSDAT_euk PF18139.1 CBY31418.1 - 2e-60 204.5 0.1 3.4e-60 203.7 0.1 1.3 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CBY31418.1 - 7.7e-13 48.1 0.4 1.4e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 CBY31418.1 - 8.3e-12 44.9 16.8 8.3e-12 44.9 16.8 1.7 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 CBY31418.1 - 0.00095 17.9 0.5 0.00095 17.9 0.5 1.7 2 0 0 2 2 2 1 Polycystin cation channel Pkinase PF00069.25 CBY31420.1 - 7.2e-61 205.9 0.1 9.8e-61 205.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31420.1 - 9e-22 77.6 0.1 1.3e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY31420.1 - 5.1e-08 32.6 0.0 8.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY31420.1 - 0.00032 20.1 1.4 0.00053 19.4 1.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY31420.1 - 0.038 13.6 0.2 0.08 12.5 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBY31420.1 - 0.082 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3512 PF12024.8 CBY31421.1 - 1.4e-12 47.6 0.2 8.6e-12 45.0 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3512) FIVAR PF07554.13 CBY31421.1 - 0.1 13.3 0.1 0.3 11.9 0.1 1.8 1 0 0 1 1 1 0 FIVAR domain Zip PF02535.22 CBY31422.1 - 1.8e-49 168.8 10.5 2.1e-49 168.5 10.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1129 PF06570.11 CBY31422.1 - 2.9 7.3 4.5 13 5.2 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) Arc_PepC_II PF06847.11 CBY31424.1 - 0.099 13.2 0.7 1.3 9.6 0.7 2.3 1 1 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Pox_polyA_pol_N PF12630.7 CBY31425.1 - 0.076 13.4 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Glycos_transf_2 PF00535.26 CBY31426.1 - 1.7e-10 41.0 0.1 6.2e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 EF-hand_6 PF13405.6 CBY31427.1 - 5.2e-09 35.3 0.4 1.4e-08 34.0 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY31427.1 - 2.4e-07 29.8 0.1 5.3e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY31427.1 - 3.2e-07 30.7 0.0 4.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CBY31427.1 - 1.2e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CBY31427.1 - 3.9e-06 26.1 0.3 8.4e-06 25.1 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY31427.1 - 5.9e-06 26.0 0.6 0.0011 18.7 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_14 PF17959.1 CBY31427.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain FGAR-AT_linker PF18072.1 CBY31427.1 - 0.042 14.4 0.0 0.062 13.9 0.0 1.5 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain ZapB PF06005.12 CBY31428.1 - 0.07 13.6 0.0 0.27 11.7 0.0 2.0 1 1 0 1 1 1 0 Cell division protein ZapB EF-hand_7 PF13499.6 CBY31430.1 - 1.3e-14 54.3 0.2 5.9e-08 33.0 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY31430.1 - 1.5e-13 49.2 2.7 0.00019 20.8 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY31430.1 - 1.8e-11 43.0 2.3 8.6e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY31430.1 - 5e-10 39.1 0.9 0.00018 21.3 0.3 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31430.1 - 7.2e-09 34.7 4.2 0.00065 19.1 1.0 3.3 3 0 0 3 3 3 3 EF hand Dockerin_1 PF00404.18 CBY31430.1 - 0.00014 21.9 3.1 0.00046 20.3 1.2 2.3 2 1 1 3 3 3 2 Dockerin type I domain PMP22_Claudin PF00822.20 CBY31431.1 - 4.9e-10 39.5 1.2 1.1e-09 38.4 1.2 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY31431.1 - 0.00015 22.0 0.7 0.00043 20.5 0.1 1.9 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Clc-like PF07062.12 CBY31431.1 - 0.006 16.1 0.0 0.006 16.1 0.0 2.5 2 2 1 3 3 3 1 Clc-like Claudin_2 PF13903.6 CBY31431.1 - 0.09 12.5 5.1 0.52 10.0 5.1 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 CBY31431.1 - 0.39 10.6 13.4 2.5 8.0 5.7 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Ail_Lom PF06316.11 CBY31432.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Prefoldin_2 PF01920.20 CBY31433.1 - 7.4e-19 67.7 6.2 7.4e-19 67.7 6.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 CBY31433.1 - 0.055 13.5 9.8 0.66 10.0 2.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 CBY31433.1 - 0.065 11.4 7.5 0.048 11.8 0.9 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 CBY31433.1 - 0.15 12.3 6.8 0.92 9.7 1.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 CBY31433.1 - 0.16 12.0 6.9 0.55 10.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY31433.1 - 0.17 10.7 7.4 1.7 7.4 0.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 CBY31433.1 - 0.18 12.3 9.1 2.1 8.9 1.7 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 CBY31433.1 - 0.21 11.2 10.4 1.7 8.3 5.3 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Bcr-Abl_Oligo PF09036.10 CBY31433.1 - 0.21 11.6 3.9 0.78 9.8 0.7 2.5 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHR10 PF18595.1 CBY31433.1 - 0.3 11.2 9.9 0.89 9.6 2.7 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 CBY31433.1 - 0.36 11.2 4.9 8.6 6.8 0.5 2.7 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 CBY31433.1 - 0.57 10.4 8.3 4 7.7 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Nas2_N PF18265.1 CBY31433.1 - 0.65 9.9 5.2 20 5.2 0.0 3.1 3 0 0 3 3 3 0 Nas2 N_terminal domain PEARLI-4 PF05278.12 CBY31433.1 - 0.83 9.2 10.9 0.46 10.0 3.7 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) TBCA PF02970.16 CBY31433.1 - 0.84 10.0 7.5 1.7 9.0 0.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A Spc24 PF08286.11 CBY31433.1 - 0.88 9.8 8.1 2.9 8.2 1.0 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF16 PF01519.16 CBY31433.1 - 1.1 9.8 13.7 2.4 8.7 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF16 Sec2p PF06428.11 CBY31433.1 - 3.3 7.8 11.3 6.7 6.8 0.5 2.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 CBY31433.1 - 7.6 7.2 9.0 3 8.5 0.8 2.9 1 1 3 4 4 4 0 SlyX FRG1 PF06229.12 CBY31434.1 - 5.4e-53 179.6 0.0 5.4e-53 179.6 0.0 2.0 2 0 0 2 2 2 1 FRG1-like domain DUF1754 PF08555.10 CBY31434.1 - 0.00044 21.0 11.9 0.00044 21.0 11.9 1.9 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Fascin PF06268.13 CBY31434.1 - 0.00066 19.9 0.0 0.0022 18.2 0.0 1.9 1 1 0 1 1 1 1 Fascin domain WRNPLPNID PF15017.6 CBY31434.1 - 1 10.3 3.1 2.3 9.1 3.1 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box TM231 PF10149.9 CBY31435.1 - 8.1e-10 38.5 3.7 2.8e-09 36.8 3.7 1.7 1 1 0 1 1 1 1 Transmembrane protein 231 FixP_N PF14715.6 CBY31435.1 - 6.3 6.6 5.4 0.49 10.2 0.5 1.6 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Sulfotransfer_4 PF17784.1 CBY31436.1 - 5.5e-56 189.8 0.0 6.4e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31436.1 - 0.014 15.7 0.0 0.051 13.9 0.0 2.0 2 1 0 2 2 2 0 Sulfotransferase family Acyl-CoA_dh_1 PF00441.24 CBY31437.1 - 4.4e-37 127.6 6.9 1.6e-34 119.3 1.9 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY31437.1 - 6.3e-26 90.4 0.5 1.4e-25 89.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY31437.1 - 2.2e-19 70.2 0.1 8e-19 68.4 0.1 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY31437.1 - 8e-15 55.3 1.3 1.5e-11 44.7 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY31437.1 - 0.0008 19.2 0.2 0.002 17.9 0.2 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Allexi_40kDa PF05549.11 CBY31437.1 - 0.096 12.2 0.4 0.19 11.2 0.4 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein I-set PF07679.16 CBY31438.1 - 0 2079.7 16.0 2.5e-15 56.3 0.0 49.9 49 0 0 49 49 49 48 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY31438.1 - 0 1996.2 52.5 1.4e-14 54.4 0.0 49.6 49 0 0 49 49 49 48 Immunoglobulin domain Ig_2 PF13895.6 CBY31438.1 - 0 1322.6 0.4 9.2e-10 38.7 0.0 50.1 50 1 1 51 51 50 48 Immunoglobulin domain ig PF00047.25 CBY31438.1 - 0 1124.2 9.4 7.4e-09 35.7 0.0 51.3 49 3 0 49 49 49 47 Immunoglobulin domain C2-set_2 PF08205.12 CBY31438.1 - 1e-127 416.6 31.5 0.0052 16.8 0.0 45.3 46 0 0 46 46 46 30 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY31438.1 - 1.6e-109 359.7 55.7 0.0056 16.8 0.0 59.9 50 21 5 57 57 56 19 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY31438.1 - 2e-71 235.4 0.0 0.033 13.7 0.0 37.4 40 0 0 40 40 39 10 Immunoglobulin domain Ig_4 PF16680.5 CBY31438.1 - 1.5e-57 191.8 5.0 0.023 14.9 0.0 36.8 43 2 2 45 45 41 7 T-cell surface glycoprotein CD3 delta chain EGF_CA PF07645.15 CBY31438.1 - 4.1e-53 177.3 117.5 8.4e-09 35.5 10.0 11.1 8 1 1 9 9 9 8 Calcium-binding EGF domain TSP_1 PF00090.19 CBY31438.1 - 5.9e-48 160.9 101.0 7.9e-10 38.8 10.2 7.6 7 0 0 7 7 6 6 Thrombospondin type 1 domain Izumo-Ig PF16706.5 CBY31438.1 - 1.7e-30 104.9 13.4 1.1 9.4 0.0 29.8 37 0 0 37 37 34 2 Izumo-like Immunoglobulin domain cEGF PF12662.7 CBY31438.1 - 1e-25 89.3 76.0 6e-10 38.9 1.3 11.2 10 0 0 10 10 10 8 Complement Clr-like EGF-like G2F PF07474.12 CBY31438.1 - 7.7e-25 87.7 0.2 2.3e-24 86.2 0.2 1.8 1 0 0 1 1 1 1 G2F domain Receptor_2B4 PF11465.8 CBY31438.1 - 5.2e-24 84.5 8.0 0.0019 18.4 0.0 15.4 13 2 2 15 15 13 2 Natural killer cell receptor 2B4 C2-set PF05790.15 CBY31438.1 - 4.7e-22 78.0 11.3 12 6.2 0.0 23.5 28 0 0 28 28 23 0 Immunoglobulin C2-set domain Adeno_E3_CR1 PF02440.15 CBY31438.1 - 1.2e-14 53.8 13.5 15 5.4 0.0 17.9 22 0 0 22 22 17 0 Adenovirus E3 region protein CR1 FXa_inhibition PF14670.6 CBY31438.1 - 6.4e-10 39.2 129.5 5.6e-08 32.9 9.4 10.8 8 1 2 10 10 9 5 Coagulation Factor Xa inhibitory site V-set_CD47 PF08204.11 CBY31438.1 - 1.8e-09 37.6 14.3 11 6.1 0.0 17.0 19 0 0 19 19 14 0 CD47 immunoglobulin-like domain EGF PF00008.27 CBY31438.1 - 8.9e-06 25.9 120.5 0.00032 20.9 4.9 11.5 10 0 0 10 10 9 4 EGF-like domain PKD_3 PF16820.5 CBY31438.1 - 0.047 13.4 2.3 3 7.7 0.0 5.4 5 0 0 5 5 4 0 PKD-like domain SPEG_u2 PF16650.5 CBY31438.1 - 0.13 12.5 0.4 46 4.3 0.0 3.3 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein CdiI_N PF18228.1 CBY31438.1 - 0.24 11.3 0.8 34 4.3 0.1 2.7 2 0 0 2 2 2 0 CdiI N-terminal domain Cadherin_4 PF17803.1 CBY31438.1 - 1.4 9.6 6.3 88 3.8 0.1 5.0 5 0 0 5 5 4 0 Bacterial cadherin-like domain EF-hand_1 PF00036.32 CBY31439.1 - 1.6e-06 27.3 0.0 0.41 10.3 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY31439.1 - 0.001 18.9 0.0 2.9 8.0 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY31439.1 - 0.0059 17.0 0.6 2.5 8.6 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31439.1 - 0.59 9.7 3.3 7 6.3 0.0 3.2 4 0 0 4 4 4 0 EF hand Serpin PF00079.20 CBY31440.1 - 3.7e-51 174.6 0.0 4.5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) MH2 PF03166.14 CBY31441.1 - 6.3e-61 205.8 3.0 1.5e-60 204.6 0.3 2.3 2 0 0 2 2 2 1 MH2 domain MH1 PF03165.16 CBY31441.1 - 1.6e-23 82.9 0.3 3.5e-23 81.8 0.3 1.6 1 0 0 1 1 1 1 MH1 domain Methyltransf_23 PF13489.6 CBY31441.1 - 5.6e-17 62.1 0.1 1.5e-16 60.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY31441.1 - 7.4e-17 61.9 0.0 1.8e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY31441.1 - 1.4e-16 60.7 0.1 2.7e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY31441.1 - 6.2e-16 58.8 0.1 2.2e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CBY31441.1 - 1.2e-15 57.6 0.1 2.1e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBY31441.1 - 2e-13 50.9 0.0 4.7e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY31441.1 - 1e-08 35.0 0.0 2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBY31441.1 - 1.5e-07 31.0 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CBY31441.1 - 3.5e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 CBY31441.1 - 8.7e-05 22.1 0.2 0.0059 16.1 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_15 PF09445.10 CBY31441.1 - 0.00044 19.9 0.2 0.00097 18.8 0.2 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 CBY31441.1 - 0.00056 18.9 0.0 0.0011 17.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CBY31441.1 - 0.0074 16.3 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CBY31441.1 - 0.0086 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 CBY31441.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 2 0 0 2 2 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.7 CBY31441.1 - 0.023 14.7 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Melibiase_2 PF16499.5 CBY31441.1 - 0.027 13.6 0.2 0.044 12.9 0.2 1.3 1 0 0 1 1 1 0 Alpha galactosidase A CmcI PF04989.12 CBY31441.1 - 0.03 14.0 0.0 0.075 12.7 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase DOT1 PF08123.13 CBY31441.1 - 0.045 13.3 0.2 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 Histone methylation protein DOT1 NAS PF03059.16 CBY31441.1 - 0.094 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein PCMT PF01135.19 CBY31441.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.26 CBY31441.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UPF0020 PF01170.18 CBY31441.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 CBY31441.1 - 0.22 10.9 0.9 0.81 9.1 0.1 2.4 2 1 0 2 2 2 0 Putative methyltransferase Dimerisation PF08100.11 CBY31442.1 - 0.052 13.6 0.3 0.65 10.1 0.1 2.5 2 1 1 3 3 3 0 Dimerisation domain Pkinase PF00069.25 CBY31443.1 - 1.4e-12 47.6 0.2 2.7e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31443.1 - 1.9e-08 34.0 0.2 5.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY31443.1 - 0.015 14.3 0.5 0.015 14.3 0.5 2.5 2 0 0 2 2 2 0 Haspin like kinase domain DUF4131 PF13567.6 CBY31445.1 - 1 9.0 5.0 9.1 5.9 5.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Alpha_GJ PF03229.13 CBY31445.1 - 2.1 8.9 14.3 5.3 7.6 14.3 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J FSA_C PF10479.9 CBY31445.1 - 4.7 5.2 11.2 5.7 4.9 11.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Insulin_TMD PF17870.1 CBY31446.1 - 0.0087 16.1 1.0 0.014 15.5 1.0 1.3 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Cation_efflux PF01545.21 CBY31447.1 - 8.7e-40 136.6 16.6 1.1e-39 136.3 16.6 1.1 1 0 0 1 1 1 1 Cation efflux family zf-C2H2_4 PF13894.6 CBY31448.1 - 7.5e-17 60.6 95.1 0.03 15.1 0.5 13.7 14 0 0 14 14 14 10 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY31448.1 - 3e-11 43.1 102.2 0.0043 17.4 0.3 14.1 14 1 0 14 14 14 10 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CBY31448.1 - 5.5e-07 29.2 0.2 5.5e-07 29.2 0.2 7.1 8 0 0 8 8 8 2 zinc-finger C2H2-type zf-met PF12874.7 CBY31448.1 - 0.00027 21.2 1.8 0.00027 21.2 1.8 9.7 13 0 0 13 13 13 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY31448.1 - 0.0013 19.0 2.5 0.0013 19.0 2.5 9.2 12 0 0 12 12 12 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY31448.1 - 0.0053 16.7 0.6 0.0053 16.7 0.6 10.7 12 0 0 12 12 12 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY31448.1 - 0.13 12.8 0.1 0.13 12.8 0.1 12.2 13 1 0 13 13 13 0 Zinc-finger double domain DUF1059 PF06348.11 CBY31448.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1059) zf_UBZ PF18439.1 CBY31448.1 - 6.2 6.5 42.6 1.7 8.3 0.1 8.9 10 0 0 10 10 10 0 Ubiquitin-Binding Zinc Finger FSAP_sig_propep PF03032.15 CBY31449.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Mon2_C PF16206.5 CBY31450.1 - 2.1e-87 294.1 11.3 1.2e-60 205.6 0.2 3.1 1 1 1 2 2 2 2 C-terminal region of Mon2 protein Sec7_N PF12783.7 CBY31450.1 - 1.1e-30 106.7 1.8 1.1e-30 106.7 1.8 4.5 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CBY31450.1 - 2.9e-25 88.9 2.4 2.9e-25 88.9 2.4 3.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CBY31450.1 - 5.3e-16 58.2 2.6 5.1e-14 51.9 0.2 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) PA28_beta PF02252.18 CBY31451.1 - 1.2e-48 164.5 3.3 2.1e-48 163.7 3.3 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CBY31451.1 - 0.00028 20.9 0.1 0.00096 19.1 0.1 1.9 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit WBP-1 PF11669.8 CBY31452.1 - 0.00065 20.3 1.8 0.019 15.6 0.1 2.2 2 0 0 2 2 2 1 WW domain-binding protein 1 ETRAMP PF09716.10 CBY31452.1 - 0.028 14.5 1.5 0.12 12.4 1.5 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF973 PF06157.11 CBY31452.1 - 0.039 13.0 0.8 0.058 12.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) zf-H2C2_2 PF13465.6 CBY31453.1 - 6.9e-17 61.0 18.9 8.6e-07 29.1 0.8 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY31453.1 - 1.2e-11 44.4 21.2 1.3e-05 25.4 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31453.1 - 3.3e-11 43.0 17.0 0.00016 22.3 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY31453.1 - 4.6e-07 30.0 12.5 0.00071 19.9 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY31453.1 - 4.5e-05 23.6 6.4 0.0022 18.2 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY31453.1 - 0.08 13.0 16.2 0.13 12.3 0.7 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY31453.1 - 0.087 13.2 6.6 7.6 6.9 0.1 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CCHC_2 PF13696.6 CBY31453.1 - 0.3 11.0 16.3 3.8 7.4 0.5 3.5 3 0 0 3 3 3 0 Zinc knuckle Zf_RING PF16744.5 CBY31453.1 - 0.32 11.2 8.1 12 6.1 0.3 3.5 2 1 1 3 3 3 0 KIAA1045 RING finger FYVE PF01363.21 CBY31453.1 - 0.32 11.2 8.7 3.5 7.8 1.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger C1_4 PF07975.12 CBY31453.1 - 0.39 11.0 6.5 12 6.2 0.1 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain C1_1 PF00130.22 CBY31453.1 - 0.47 10.4 5.0 0.25 11.3 0.3 2.3 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.6 CBY31453.1 - 0.48 10.4 8.1 9.6 6.2 0.8 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_ribbon_recom PF13408.6 CBY31453.1 - 0.76 10.3 7.2 0.14 12.6 3.2 1.9 2 0 0 2 2 1 0 Recombinase zinc beta ribbon domain zf-Dof PF02701.15 CBY31453.1 - 2.5 8.3 7.7 28 5.0 4.4 3.1 2 1 1 3 3 3 0 Dof domain, zinc finger zf-C2H2_3rep PF18868.1 CBY31453.1 - 4.2 8.1 9.1 18 6.0 0.4 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-FCS PF06467.14 CBY31453.1 - 4.4 7.3 6.9 18 5.4 0.2 2.6 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_11 PF16622.5 CBY31453.1 - 4.6 7.1 11.6 4.2 7.2 0.2 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type Phospholip_A2_1 PF00068.19 CBY31456.1 - 2e-14 54.0 2.5 2e-14 54.0 2.5 2.1 2 0 0 2 2 2 1 Phospholipase A2 VbhA PF18495.1 CBY31456.1 - 0.23 11.3 0.2 0.48 10.3 0.2 1.4 1 0 0 1 1 1 0 Antitoxin VbhA Cadherin PF00028.17 CBY31457.1 - 7.8e-121 394.9 19.5 5.5e-21 74.8 0.2 8.1 8 0 0 8 8 8 7 Cadherin domain 7tm_2 PF00002.24 CBY31457.1 - 2.7e-25 89.1 10.1 5e-25 88.2 10.1 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Laminin_G_2 PF02210.24 CBY31457.1 - 1.7e-23 83.6 0.5 5e-14 53.0 0.1 2.7 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CBY31457.1 - 8.1e-18 64.9 0.4 1.2e-10 41.7 0.0 3.2 3 0 0 3 3 2 2 Laminin G domain EGF PF00008.27 CBY31457.1 - 1.2e-14 54.3 91.7 2.9e-06 27.5 6.6 8.4 8 0 0 8 8 7 5 EGF-like domain GPS PF01825.21 CBY31457.1 - 2.7e-12 47.0 3.1 2.7e-12 47.0 3.1 3.5 3 0 0 3 3 1 1 GPCR proteolysis site, GPS, motif Cadherin_2 PF08266.12 CBY31457.1 - 2.3e-10 40.1 4.4 0.23 11.3 0.0 7.5 8 0 0 8 8 8 3 Cadherin-like Laminin_EGF PF00053.24 CBY31457.1 - 2.1e-07 31.0 14.1 2.1e-07 31.0 14.1 8.3 5 2 2 7 7 7 2 Laminin EGF domain Cadherin_3 PF16184.5 CBY31457.1 - 2.2e-06 27.6 15.6 2.4 8.2 0.1 7.1 7 0 0 7 7 7 3 Cadherin-like Cadherin_4 PF17803.1 CBY31457.1 - 0.00046 20.8 27.7 0.032 14.9 0.4 7.0 6 0 0 6 6 6 1 Bacterial cadherin-like domain RET_CLD1 PF17756.1 CBY31457.1 - 0.0011 19.3 0.0 1.7 8.9 0.0 5.1 6 0 0 6 6 5 1 RET Cadherin like domain 1 EGF_2 PF07974.13 CBY31457.1 - 0.0056 17.0 10.2 0.0056 17.0 10.2 9.5 7 2 1 8 8 6 4 EGF-like domain hEGF PF12661.7 CBY31457.1 - 0.007 17.0 6.7 0.007 17.0 6.7 8.4 9 0 0 9 9 6 3 Human growth factor-like EGF Laminin_G_3 PF13385.6 CBY31457.1 - 0.011 15.8 0.1 0.22 11.7 0.0 3.1 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Big_9 PF17963.1 CBY31457.1 - 0.73 10.6 18.0 4.2 8.2 0.2 6.3 6 0 0 6 6 6 0 Bacterial Ig domain YpmT PF17431.2 CBY31457.1 - 3.7 7.7 6.0 1.5 8.9 1.0 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like PsbP PF01789.16 CBY31457.1 - 4.7 7.3 6.4 1.2 9.3 0.1 3.1 4 0 0 4 4 3 0 PsbP DUF3902 PF13042.6 CBY31458.1 - 0.32 10.6 6.9 0.41 10.2 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Phospholip_A2_1 PF00068.19 CBY31459.1 - 1.5e-17 64.1 8.4 6.3e-17 62.1 8.4 1.9 1 1 0 1 1 1 1 Phospholipase A2 PI3_PI4_kinase PF00454.27 CBY31460.1 - 6e-39 134.3 1.3 2.8e-25 89.6 0.4 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBY31460.1 - 7.5e-25 87.4 1.5 1.4e-24 86.5 1.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) C2 PF00168.30 CBY31460.1 - 1.7e-11 44.3 0.1 2.2e-09 37.5 0.0 2.8 3 0 0 3 3 3 1 C2 domain PI3K_C2 PF00792.24 CBY31460.1 - 1.1e-10 41.6 0.0 1.1e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Glyco_transf_54 PF04666.13 CBY31460.1 - 0.022 13.6 0.6 8.8 5.1 0.0 3.1 3 0 0 3 3 3 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4135 PF13575.6 CBY31460.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) HLH PF00010.26 CBY31462.1 - 4.4e-06 26.6 1.3 8.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Sec66 PF09802.9 CBY31462.1 - 0.013 15.0 0.6 0.024 14.2 0.6 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 CagA PF03507.13 CBY31462.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 CagA exotoxin Mis12 PF05859.12 CBY31462.1 - 0.31 11.1 2.6 1.4 9.0 0.2 2.6 2 0 0 2 2 2 0 Mis12 protein CaM_binding PF07839.11 CBY31462.1 - 0.6 10.9 0.1 0.6 10.9 0.1 2.7 2 1 1 3 3 3 0 Plant calmodulin-binding domain Sulfotransfer_2 PF03567.14 CBY31463.1 - 0.008 16.1 3.7 0.11 12.3 3.7 2.3 1 1 0 1 1 1 1 Sulfotransferase family Collagen PF01391.18 CBY31464.1 - 4.1e-28 96.9 105.1 7.4e-09 35.2 29.8 4.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 CBY31465.1 - 1.1e-103 339.0 428.8 3.6e-09 36.2 27.0 14.3 2 1 11 13 13 13 12 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY31465.1 - 4.2e-62 209.5 0.1 6.3e-62 208.9 0.1 1.3 1 0 0 1 1 1 1 Fibrillar collagen C-terminal domain Trypsin PF00089.26 CBY31466.1 - 2.4e-56 191.0 0.1 4.2e-56 190.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY31466.1 - 2.2e-26 92.3 2.7 3e-13 50.0 0.2 3.6 3 0 0 3 3 3 3 CUB domain Trypsin_2 PF13365.6 CBY31466.1 - 0.0006 20.7 0.0 0.0013 19.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain BTB PF00651.31 CBY31467.1 - 2.3e-21 76.1 0.0 6e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Adeno_PV PF03910.13 CBY31467.1 - 0.052 12.3 0.7 6.6 5.3 0.1 2.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV GAD-like PF08887.11 CBY31467.1 - 0.12 12.2 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain fn3 PF00041.21 CBY31468.1 - 4.4e-31 107.1 16.2 0.00023 21.4 0.3 8.8 8 1 0 8 8 8 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY31468.1 - 2.5e-05 24.8 13.2 1.4 9.5 0.1 7.5 5 2 1 6 6 6 2 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 CBY31468.1 - 0.039 14.3 1.3 67 4.0 0.0 5.1 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) Toxin_TOLIP PF00087.21 CBY31468.1 - 2.5 8.4 16.7 4.8 7.5 16.7 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein BAMBI PF06211.12 CBY31468.1 - 3.2 8.1 8.5 6.6 7.0 8.5 1.5 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Headcase PF16002.5 CBY31470.1 - 2.7e-75 252.2 9.8 4e-75 251.6 9.8 1.2 1 0 0 1 1 1 1 Headcase protein HECA PF15353.6 CBY31470.1 - 7.9e-19 67.8 1.0 7.9e-19 67.8 1.0 2.2 3 0 0 3 3 3 1 Headcase protein family homologue Rhodanese_C PF12368.8 CBY31470.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 4.6 4 1 0 4 4 4 1 Rhodanase C-terminal EF-hand_1 PF00036.32 CBY31471.1 - 6.6e-15 53.5 10.0 2.9e-05 23.3 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBY31471.1 - 1.1e-14 54.6 3.5 6.7e-10 39.3 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY31471.1 - 1.4e-14 52.7 7.5 3.7e-06 26.4 0.2 3.3 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY31471.1 - 2.3e-06 27.3 6.5 7.3e-05 22.5 0.5 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31471.1 - 5.4e-06 25.7 15.3 7.4e-05 22.1 0.3 4.0 4 0 0 4 4 4 3 EF hand Caleosin PF05042.13 CBY31471.1 - 0.0099 15.8 0.2 0.021 14.7 0.0 1.6 1 1 1 2 2 2 1 Caleosin related protein Dockerin_1 PF00404.18 CBY31471.1 - 0.14 12.3 0.0 0.74 10.1 0.0 2.1 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 CBY31471.1 - 1.8 8.6 4.1 47 4.0 0.2 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Sema PF01403.19 CBY31472.1 - 9.1e-12 44.5 1.4 1.2e-11 44.1 1.4 1.1 1 0 0 1 1 1 1 Sema domain Ald_Xan_dh_C2 PF02738.18 CBY31473.1 - 9e-188 625.2 0.0 1.3e-187 624.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY31473.1 - 1.4e-36 125.8 0.0 2.9e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CBY31473.1 - 7.3e-30 102.8 0.1 1.7e-29 101.6 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 CBY31473.1 - 1.5e-26 92.5 0.0 1.1e-25 89.8 0.0 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 CBY31473.1 - 3.3e-26 91.8 0.1 1e-25 90.2 0.1 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 CBY31473.1 - 2.7e-09 36.9 1.0 9.2e-09 35.1 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 CBY31473.1 - 0.69 9.8 5.2 2.2 8.2 5.2 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B zf-CpG_bind_C PF12269.8 CBY31474.1 - 2.1e-73 247.0 7.8 2.1e-73 247.0 7.8 2.2 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD PF00628.29 CBY31474.1 - 0.00019 21.2 2.8 0.00019 21.2 2.8 3.4 3 1 1 4 4 4 1 PHD-finger DUF1644 PF07800.12 CBY31474.1 - 0.017 15.2 11.7 0.069 13.2 6.2 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) DER1 PF04511.15 CBY31475.1 - 2.7e-52 177.5 12.4 3.1e-52 177.3 12.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF983 PF06170.12 CBY31475.1 - 7.8 7.0 13.3 15 6.1 6.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF983) RRM_1 PF00076.22 CBY31476.1 - 1.1e-26 92.4 2.0 9e-16 57.5 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY31476.1 - 2.2e-10 40.5 0.4 7.4e-05 22.8 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY31476.1 - 0.015 15.3 0.2 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 CBY31476.1 - 0.028 14.4 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Epimerase PF01370.21 CBY31477.1 - 0.0051 16.3 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Meis_PKNOX_N PF16493.5 CBY31479.1 - 7.8e-24 83.8 0.6 1.3e-23 83.2 0.6 1.3 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 TSP_1 PF00090.19 CBY31480.1 - 2.7e-05 24.3 9.1 2.7e-05 24.3 9.1 3.6 3 0 0 3 3 3 1 Thrombospondin type 1 domain DUF572 PF04502.13 CBY31480.1 - 4.8 6.7 23.9 0.24 11.0 18.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Utp14 PF04615.13 CBY31480.1 - 5 5.6 15.6 8.6 4.8 15.6 1.3 1 0 0 1 1 1 0 Utp14 protein MH1 PF03165.16 CBY31481.1 - 0.0046 17.1 0.1 0.012 15.8 0.1 1.6 2 0 0 2 2 2 1 MH1 domain TAN PF11640.8 CBY31481.1 - 0.081 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair MH1 PF03165.16 CBY31482.1 - 1.5e-12 47.6 0.4 1.8e-12 47.3 0.4 1.1 1 0 0 1 1 1 1 MH1 domain Nitrophorin PF02087.15 CBY31482.1 - 0.0063 16.5 0.1 0.007 16.4 0.1 1.1 1 0 0 1 1 1 1 Nitrophorin MH2 PF03166.14 CBY31483.1 - 2e-46 158.5 0.4 2.8e-46 158.1 0.4 1.2 1 0 0 1 1 1 1 MH2 domain PALP PF00291.25 CBY31485.1 - 2.4e-56 191.3 0.3 3.6e-56 190.8 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme EF-hand_1 PF00036.32 CBY31485.1 - 2.4e-07 29.8 0.4 6.2e-06 25.4 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY31485.1 - 1.7e-06 27.5 0.1 0.00036 20.2 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY31485.1 - 6e-06 25.5 0.7 0.00032 20.1 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY31485.1 - 1.1e-05 25.8 0.0 3.1e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY31485.1 - 6.8e-05 22.6 0.2 0.00028 20.7 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair ACT PF01842.25 CBY31485.1 - 0.097 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain VWA_3 PF13768.6 CBY31486.1 - 2.3e-13 50.4 0.0 1.3e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 CBY31486.1 - 1.1e-08 35.5 0.3 0.00069 19.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VIT PF08487.10 CBY31486.1 - 1.7e-05 25.0 1.2 4.7e-05 23.6 1.2 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 CBY31486.1 - 6.7e-05 23.5 0.1 0.5 11.0 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY31486.1 - 0.0021 17.5 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Glycos_transf_2 PF00535.26 CBY31487.1 - 1.8e-07 31.1 0.0 2.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Tcell_CD4_C PF12104.8 CBY31488.1 - 3.4 7.7 8.2 0.13 12.2 1.7 2.0 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region PALP PF00291.25 CBY31489.1 - 1.5e-45 155.8 0.2 2.1e-45 155.4 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 CBY31489.1 - 0.052 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ACT domain PfkB PF00294.24 CBY31491.1 - 1.9e-13 50.4 0.1 1.9e-12 47.2 0.1 1.9 1 1 1 2 2 2 2 pfkB family carbohydrate kinase DUF4200 PF13863.6 CBY31496.1 - 8.3e-24 84.3 11.4 9.5e-24 84.1 11.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) RNA_pol_Rpb6 PF01192.22 CBY31496.1 - 0.047 13.6 0.5 0.079 12.9 0.5 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb6 Cas_Cas1 PF01867.16 CBY31496.1 - 0.082 12.0 3.8 0.1 11.7 3.8 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Ribosomal_S20p PF01649.18 CBY31496.1 - 0.12 13.0 0.6 0.12 13.0 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein S20 DUF2730 PF10805.8 CBY31496.1 - 0.97 9.6 6.0 4 7.6 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) WD40 PF00400.32 CBY31497.1 - 0.088 13.7 0.3 0.48 11.4 0.0 2.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 CBY31499.1 - 0.0012 18.2 0.0 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain DUF4816 PF16086.5 CBY31499.1 - 0.26 11.2 1.8 0.67 9.9 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) Pkinase PF00069.25 CBY31500.1 - 9e-10 38.3 2.3 2.4e-09 36.9 1.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31500.1 - 7.4e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 CBY31501.1 - 1.4e-28 100.0 6.9 1.9e-28 99.5 6.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY31501.1 - 2.5e-24 85.8 9.6 2.5e-24 85.8 9.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF973 PF06157.11 CBY31501.1 - 0.028 13.5 2.6 0.043 12.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) CCT_2 PF09425.10 CBY31503.1 - 0.083 12.8 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Divergent CCT motif Ycf9 PF01737.17 CBY31504.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 YCF9 Actin PF00022.19 CBY31505.1 - 1.5e-84 284.0 0.0 1.1e-51 175.7 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 CBY31505.1 - 0.00019 21.8 0.0 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 CBY31505.1 - 0.00059 18.7 0.0 0.11 11.4 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein RTC PF01137.21 CBY31506.1 - 2.4e-55 187.2 0.0 2.8e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RAI16-like PF10257.9 CBY31507.1 - 9e-62 209.0 0.3 1.3e-61 208.5 0.3 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein zf-C2H2 PF00096.26 CBY31508.1 - 0.00011 22.4 1.2 0.00011 22.4 1.2 6.5 6 1 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31508.1 - 0.00083 20.0 1.0 0.00083 20.0 1.0 5.9 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY31508.1 - 0.021 15.1 0.1 0.021 15.1 0.1 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 CBY31508.1 - 0.029 14.0 12.8 0.062 13.0 0.9 4.1 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY31508.1 - 0.069 13.6 0.1 0.069 13.6 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY31508.1 - 2.4 8.7 27.6 0.63 10.6 1.0 5.4 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 CBY31508.1 - 5 7.1 8.6 0.52 10.3 0.4 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type RAI16-like PF10257.9 CBY31509.1 - 1e-83 281.2 4.1 1.3e-83 280.9 4.1 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein RTC PF01137.21 CBY31509.1 - 8.7e-06 25.1 0.0 3.2e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF4792 PF16040.5 CBY31510.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) RAI16-like PF10257.9 CBY31511.1 - 6.1e-81 272.1 6.2 8.4e-81 271.6 6.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Coatomer_WDAD PF04053.14 CBY31512.1 - 9.7e-11 41.4 7.8 4.9e-05 22.6 0.0 4.3 4 1 1 5 5 5 4 Coatomer WD associated region ANAPC4_WD40 PF12894.7 CBY31512.1 - 6.4e-08 32.8 3.8 7.8e-05 22.9 0.2 4.8 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PPR PF01535.20 CBY31512.1 - 1.6e-05 24.8 3.1 0.61 10.5 0.0 5.7 5 2 1 6 6 6 1 PPR repeat Clathrin PF00637.20 CBY31512.1 - 0.00012 22.0 0.5 0.016 15.1 0.0 3.3 3 1 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 CBY31512.1 - 0.0002 22.1 0.8 0.12 13.3 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat TPR_7 PF13176.6 CBY31512.1 - 0.0051 16.7 0.8 1.7 8.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HPS3_N PF14761.6 CBY31512.1 - 0.012 15.1 0.0 4 6.9 0.0 3.0 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 SNAP PF14938.6 CBY31512.1 - 0.05 13.0 0.9 8.4 5.7 0.1 2.4 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP DEP PF00610.21 CBY31513.1 - 5.4e-17 61.6 0.1 1.7e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1539 PF07560.11 CBY31513.1 - 7.7e-05 22.8 1.1 0.027 14.6 0.1 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) RhoGAP PF00620.27 CBY31513.1 - 0.0074 16.1 0.4 0.023 14.5 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain FHIPEP PF00771.20 CBY31513.1 - 0.054 12.0 0.1 0.087 11.3 0.1 1.3 1 0 0 1 1 1 0 FHIPEP family Pkinase PF00069.25 CBY31515.1 - 3.2e-34 118.5 0.8 6.1e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31515.1 - 4.8e-15 55.5 0.0 1.3e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4407 PF14362.6 CBY31515.1 - 0.78 9.0 14.6 1.3 8.3 7.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 CBY31515.1 - 2.3 8.0 29.2 7.2 6.4 15.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 CBY31515.1 - 4.3 7.4 13.7 7.3 6.7 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CBY31515.1 - 4.4 7.9 14.8 0.21 12.2 0.5 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc42p PF11544.8 CBY31515.1 - 7.1 6.7 17.6 5.9 7.0 4.9 4.5 3 1 0 4 4 4 0 Spindle pole body component Spc42p IF-2B PF01008.17 CBY31516.1 - 7.7e-81 271.4 0.7 9.7e-81 271.1 0.7 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TSP_1 PF00090.19 CBY31517.1 - 2.5e-07 30.8 9.7 9.2e-06 25.8 2.5 3.6 2 0 0 2 2 2 2 Thrombospondin type 1 domain PAN_1 PF00024.26 CBY31517.1 - 1.7e-06 27.9 8.5 0.0098 15.8 0.6 3.4 2 0 0 2 2 2 2 PAN domain Kelch_4 PF13418.6 CBY31517.1 - 0.0019 18.1 1.3 12 6.0 0.1 4.5 4 1 0 4 4 4 2 Galactose oxidase, central domain PAN_4 PF14295.6 CBY31517.1 - 0.0033 17.3 2.2 0.0033 17.3 2.2 4.7 5 0 0 5 5 5 1 PAN domain GSHPx PF00255.19 CBY31519.1 - 6.8e-21 73.9 0.1 2.4e-20 72.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione peroxidase DnaJ PF00226.31 CBY31519.1 - 4.9e-06 26.6 0.2 0.0098 16.0 0.0 2.8 1 1 1 2 2 2 2 DnaJ domain AhpC-TSA PF00578.21 CBY31519.1 - 0.0024 17.8 0.3 0.013 15.5 0.1 2.2 2 1 0 2 2 2 1 AhpC/TSA family DUF4407 PF14362.6 CBY31519.1 - 0.078 12.3 0.4 13 5.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EF-hand_7 PF13499.6 CBY31520.1 - 9.9e-06 25.9 0.1 1.9e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY31520.1 - 9.9e-05 21.6 0.4 0.00024 20.4 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY31520.1 - 0.00011 21.9 0.4 0.00038 20.1 0.0 2.1 3 0 0 3 3 3 1 EF-hand domain CLCA PF08434.11 CBY31520.1 - 0.004 16.5 0.3 0.0046 16.3 0.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal EF-hand_8 PF13833.6 CBY31520.1 - 0.04 13.8 0.2 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain pair BSMAP PF12280.8 CBY31521.1 - 0.0065 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF5385 PF17359.2 CBY31521.1 - 0.015 14.9 0.1 0.015 14.9 0.1 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5385) OAD_gamma PF04277.13 CBY31521.1 - 0.02 15.5 0.1 0.047 14.3 0.1 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TMEM154 PF15102.6 CBY31521.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family OATP PF03137.20 CBY31521.1 - 0.032 12.5 0.0 0.053 11.8 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_Mycoplasma PF07672.13 CBY31521.1 - 0.047 13.0 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter Spore_YhaL PF14147.6 CBY31521.1 - 0.08 12.6 1.4 0.19 11.5 0.4 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL Orf78 PF06024.12 CBY31521.1 - 0.11 12.8 0.0 0.44 10.9 0.0 2.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF4286 PF14114.6 CBY31521.1 - 0.11 13.0 0.2 0.49 10.9 0.1 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4286) DUF4381 PF14316.6 CBY31521.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 CBY31521.1 - 0.14 13.1 0.0 0.42 11.5 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 CBY31521.1 - 0.14 12.3 3.8 0.31 11.2 3.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FeoB_associated PF12669.7 CBY31521.1 - 0.54 10.7 2.6 1.5 9.2 2.6 1.8 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein zf-Di19 PF05605.12 CBY31522.1 - 0.0038 17.5 26.6 0.0042 17.3 0.0 5.4 4 2 1 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CBY31522.1 - 0.026 15.4 31.5 0.27 12.2 0.1 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY31522.1 - 0.13 12.1 4.5 0.96 9.3 4.5 2.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_12 PF18658.1 CBY31522.1 - 0.13 11.8 14.2 3.4 7.3 0.1 4.6 4 1 1 5 5 5 0 Zinc-finger C2H2-type DUF2321 PF10083.9 CBY31522.1 - 4.3 6.9 6.8 4.6 6.8 0.3 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ECH_1 PF00378.20 CBY31523.1 - 2.6e-58 197.3 0.1 2.9e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY31523.1 - 3.4e-30 105.7 0.2 7.7e-30 104.5 0.2 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MBT PF02820.18 CBY31525.1 - 1.6e-58 195.0 0.4 1.1e-19 70.5 0.0 4.3 4 0 0 4 4 4 4 mbt repeat Ta0938 PF11494.8 CBY31525.1 - 0.015 15.6 0.3 0.037 14.3 0.3 1.7 1 0 0 1 1 1 0 Ta0938 POPLD PF08170.12 CBY31525.1 - 0.019 15.3 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 POPLD (NUC188) domain BPA_C PF18040.1 CBY31525.1 - 0.2 11.6 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 beta porphyranase A C-terminal VPS13_C PF16909.5 CBY31526.1 - 1.7e-49 168.0 8.3 1.5e-45 155.1 1.6 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CBY31526.1 - 1.1e-36 126.9 9.2 1.2e-34 120.2 4.6 3.7 2 1 0 2 2 2 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CBY31526.1 - 9.2e-27 93.5 0.2 5.7e-26 90.9 0.1 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CBY31526.1 - 2.2e-26 92.7 1.4 2.2e-26 92.7 1.4 3.8 4 0 0 4 4 4 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 CBY31526.1 - 1.9e-24 86.5 0.5 2.8e-21 76.1 0.1 3.7 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 CBY31526.1 - 1.7e-08 34.7 0.0 6.1e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain MKLP1_Arf_bdg PF16540.5 CBY31529.1 - 0.027 14.5 7.3 0.092 12.8 4.9 2.4 1 1 1 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Mgr1 PF08602.10 CBY31529.1 - 2.3 7.0 8.8 3 6.6 8.8 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit CDC45 PF02724.14 CBY31529.1 - 5.4 5.2 9.4 5.9 5.1 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein CAMSAP_CKK PF08683.11 CBY31530.1 - 2.3e-39 134.2 0.0 3.7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Zona_pellucida PF00100.23 CBY31533.1 - 3.7e-07 30.2 2.6 4.3e-07 30.0 2.6 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain LRR_4 PF12799.7 CBY31534.1 - 4.7e-11 42.7 7.2 2.9e-06 27.5 0.0 3.2 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY31534.1 - 2.4e-10 40.2 1.5 4.7e-06 26.2 0.2 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBY31534.1 - 0.00051 19.8 4.3 0.041 13.6 0.1 2.2 2 0 0 2 2 2 2 Leucine rich repeat KH_1 PF00013.29 CBY31535.1 - 9.8e-08 31.7 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 KH domain TUDOR PF00567.24 CBY31535.1 - 3.1e-07 30.4 0.1 2.5e-05 24.3 0.0 3.1 3 0 0 3 3 3 1 Tudor domain KH_2 PF07650.17 CBY31535.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_4 PF13083.6 CBY31535.1 - 0.18 11.7 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 KH domain Spectrin PF00435.21 CBY31536.1 - 1.4e-146 478.7 255.2 5.2e-17 62.2 5.5 22.3 20 2 2 22 22 22 21 Spectrin repeat EFhand_Ca_insen PF08726.10 CBY31536.1 - 1.3e-16 60.4 2.1 3.4e-16 59.1 0.1 2.9 3 0 0 3 3 3 1 Ca2+ insensitive EF hand SH3_1 PF00018.28 CBY31536.1 - 3.4e-07 29.8 0.0 1.2e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY31536.1 - 2.9e-06 26.9 0.0 7.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_6 PF13405.6 CBY31536.1 - 1.7e-05 24.4 0.4 0.00024 20.8 0.2 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY31536.1 - 2.1e-05 23.8 1.1 0.00011 21.4 0.3 2.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY31536.1 - 0.00014 22.3 2.1 0.00014 22.3 2.1 5.4 4 0 0 4 4 4 1 EF-hand domain pair SH3_9 PF14604.6 CBY31536.1 - 0.00017 21.4 0.0 0.00066 19.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PKcGMP_CC PF16808.5 CBY31537.1 - 0.013 15.3 1.1 0.043 13.7 1.1 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_U57 PF05582.12 CBY31537.1 - 0.26 10.5 6.3 0.26 10.5 0.7 2.3 1 1 1 2 2 2 0 YabG peptidase U57 TBCA PF02970.16 CBY31537.1 - 2.7 8.4 10.5 0.086 13.2 3.8 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor A HSBP1 PF06825.12 CBY31538.1 - 0.024 14.5 0.2 0.057 13.3 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SF-assemblin PF06705.11 CBY31538.1 - 0.03 13.7 1.1 0.048 13.0 1.1 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin ABC2_membrane_3 PF12698.7 CBY31539.1 - 3.8e-29 101.9 7.5 5.2e-29 101.4 7.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CBY31539.1 - 1e-22 81.1 0.0 3.3e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBY31539.1 - 2.7e-09 37.2 0.0 1.6e-05 24.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 CBY31539.1 - 7.5e-07 28.8 5.8 1.3e-06 28.0 5.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_23 PF13476.6 CBY31539.1 - 0.11 13.0 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CBY31540.1 - 9.3e-65 218.6 0.0 1.4e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31540.1 - 2.3e-35 122.1 0.0 3.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CBY31540.1 - 2.2e-28 98.5 0.2 4.4e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 C2 domain C1_1 PF00130.22 CBY31540.1 - 3.7e-27 94.0 22.4 7.9e-14 51.3 4.8 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CBY31540.1 - 1.3e-05 25.8 0.6 4.4e-05 24.1 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY31540.1 - 2.7e-05 23.3 0.5 5e-05 22.4 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain C1_2 PF03107.16 CBY31540.1 - 0.0033 17.7 16.7 0.0033 17.7 2.8 3.1 3 0 0 3 3 3 1 C1 domain DOCK-C2 PF14429.6 CBY31540.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins PHD_2 PF13831.6 CBY31540.1 - 0.022 14.3 0.8 0.022 14.3 0.8 3.5 4 0 0 4 4 3 0 PHD-finger APH PF01636.23 CBY31540.1 - 0.022 14.7 0.1 0.066 13.1 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY31540.1 - 0.036 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RNA_POL_M_15KD PF02150.16 CBY31540.1 - 0.044 13.7 0.7 0.044 13.7 0.7 3.1 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit Kdo PF06293.14 CBY31540.1 - 0.098 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YccV-like PF08755.11 CBY31540.1 - 0.16 12.5 0.3 0.84 10.2 0.1 2.3 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like eIF-4B PF06273.11 CBY31540.1 - 0.72 8.8 6.0 1.1 8.2 6.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DZR PF12773.7 CBY31540.1 - 1.5 8.9 13.3 2 8.5 3.2 3.3 3 0 0 3 3 3 0 Double zinc ribbon DUF2318 PF10080.9 CBY31540.1 - 1.8 8.7 11.3 0.041 14.0 0.9 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) zf-RING-like PF08746.11 CBY31540.1 - 2.8 8.3 18.2 7.2 7.0 3.4 2.9 2 0 0 2 2 2 0 RING-like domain zf-RING_9 PF13901.6 CBY31540.1 - 3.3 7.6 18.6 0.37 10.8 3.1 2.8 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon Cob_adeno_trans PF01923.18 CBY31541.1 - 4.2e-55 186.3 0.1 4.9e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DXP_synthase_N PF13292.6 CBY31541.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase BRO1 PF03097.18 CBY31542.1 - 2.6e-78 263.5 0.0 4.2e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain HR1 PF02185.16 CBY31542.1 - 6.2e-10 39.0 0.0 1.6e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Hr1 repeat PDZ PF00595.24 CBY31542.1 - 1.2e-09 38.3 1.3 1.8e-09 37.8 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBY31542.1 - 1.6e-07 31.1 0.2 1.6e-07 31.1 0.2 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY31542.1 - 6e-06 26.5 0.1 1.5e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain DUF5050 PF16472.5 CBY31543.1 - 0.33 10.2 1.5 0.73 9.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) HSA PF07529.13 CBY31544.1 - 2.7e-13 50.0 3.1 2.7e-13 50.0 3.1 2.7 2 1 1 3 3 3 1 HSA Helicase_C PF00271.31 CBY31544.1 - 0.0034 17.7 0.2 0.039 14.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VPS9 PF02204.18 CBY31545.1 - 3.8e-20 72.0 0.0 3.4e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 CBY31546.1 - 1.3e-13 51.2 0.0 2.6e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase KASH_CCD PF14662.6 CBY31547.1 - 0.04 13.7 23.7 0.51 10.1 15.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1495 PF07381.11 CBY31547.1 - 0.077 12.8 0.2 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) OrsD PF12013.8 CBY31547.1 - 0.078 13.4 1.0 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Calici_MSP PF05752.11 CBY31547.1 - 0.12 12.2 1.0 0.3 10.9 0.8 1.7 1 1 0 1 1 1 0 Calicivirus minor structural protein TPR_MLP1_2 PF07926.12 CBY31547.1 - 0.26 11.4 21.4 0.051 13.6 3.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 CBY31547.1 - 3.1 8.0 18.8 34 4.7 9.5 4.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 CBY31547.1 - 3.3 8.0 23.9 0.03 14.6 7.2 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 LsmAD PF06741.13 CBY31547.1 - 8.5 7.0 11.9 0.79 10.3 0.9 3.5 1 1 2 3 3 3 0 LsmAD domain DUF2613 PF11021.8 CBY31548.1 - 0.23 11.6 3.3 0.37 10.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4545 PF15078.6 CBY31549.1 - 0.0037 16.3 0.1 0.0042 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4545) KCNQ_channel PF03520.14 CBY31550.1 - 3.7e-36 124.7 0.6 6.5e-36 123.9 0.6 1.3 1 0 0 1 1 1 1 KCNQ voltage-gated potassium channel Ion_trans PF00520.31 CBY31550.1 - 1.2e-13 50.9 8.7 2.3e-13 50.0 7.5 2.0 2 0 0 2 2 2 1 Ion transport protein TAF6_C PF07571.13 CBY31550.1 - 0.053 13.9 0.1 71 3.8 0.0 3.3 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain DnaJ_C PF01556.18 CBY31551.1 - 3.3e-30 105.1 0.0 4.3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY31551.1 - 1.7e-11 44.0 0.2 3.5e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBY31551.1 - 1.3e-05 25.4 10.1 3.9e-05 23.9 10.1 1.9 1 1 0 1 1 1 1 DnaJ central domain SR-25 PF10500.9 CBY31551.1 - 0.0071 16.0 1.8 0.0071 16.0 1.8 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 CBY31551.1 - 0.047 14.2 0.9 0.088 13.4 0.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain TSGP1 PF07771.11 CBY31551.1 - 0.12 12.5 1.6 0.25 11.5 1.6 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 WD40 PF00400.32 CBY31552.1 - 6.3e-31 105.9 10.2 6.2e-07 30.0 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Prp19 PF08606.11 CBY31552.1 - 2.6e-17 62.5 0.8 5.2e-17 61.6 0.8 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 CBY31552.1 - 2.9e-14 53.1 1.3 0.00052 20.3 0.0 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY31552.1 - 2.5e-07 29.7 2.4 0.00047 18.9 0.4 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 U-box PF04564.15 CBY31552.1 - 1.7e-05 24.9 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain Ge1_WD40 PF16529.5 CBY31552.1 - 0.00073 18.6 0.0 0.015 14.3 0.0 3.0 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBY31552.1 - 0.0084 15.5 0.0 0.16 11.3 0.0 2.4 1 1 2 3 3 3 2 WD40-like domain zf-NOSIP PF15906.5 CBY31552.1 - 0.012 15.7 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein tRNA_bind_2 PF13725.6 CBY31552.1 - 0.07 12.8 1.6 0.1 12.3 1.6 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain UPF0449 PF15136.6 CBY31552.1 - 0.68 10.4 3.5 3 8.4 3.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Seryl_tRNA_N PF02403.22 CBY31552.1 - 2.4 8.4 9.5 4.5 7.5 9.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_9 PF00759.19 CBY31553.1 - 4.2e-32 112.1 0.0 4.8e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Connexin PF00029.19 CBY31554.1 - 2.1e-84 283.0 11.9 6.9e-84 281.3 11.9 1.7 1 1 0 1 1 1 1 Connexin Glyco_hydro_9 PF00759.19 CBY31555.1 - 2.7e-74 251.1 7.2 3.8e-74 250.6 7.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sushi PF00084.20 CBY31555.1 - 0.00025 21.6 1.8 0.00063 20.3 1.8 1.7 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) CBM_2 PF00553.19 CBY31555.1 - 0.034 14.5 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 Cellulose binding domain RNase_T PF00929.24 CBY31556.1 - 2.4e-13 51.0 0.0 3.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Ku_PK_bind PF08785.11 CBY31556.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like DUF1364 PF07102.12 CBY31556.1 - 0.15 12.0 0.1 0.38 10.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) TPPK_C PF12555.8 CBY31557.1 - 0.0042 17.1 0.1 0.0072 16.4 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal SLATT_5 PF18160.1 CBY31557.1 - 0.01 15.2 0.8 0.01 15.2 0.8 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3974 PF13120.6 CBY31557.1 - 0.46 10.6 2.1 0.29 11.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) cNMP_binding PF00027.29 CBY31558.1 - 7.5e-12 45.2 0.1 2.2e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ras PF00071.22 CBY31559.1 - 2.8e-51 173.3 0.0 3.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY31559.1 - 2.2e-30 105.3 0.1 4.7e-30 104.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY31559.1 - 1.9e-10 40.4 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY31559.1 - 0.00014 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zip PF02535.22 CBY31560.1 - 1.1e-33 116.8 26.8 2.4e-26 92.8 16.5 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF21 PF01595.20 CBY31560.1 - 0.01 15.6 3.1 0.01 15.6 3.1 2.6 3 1 1 4 4 4 0 Cyclin M transmembrane N-terminal domain fn3 PF00041.21 CBY31561.1 - 1.3e-05 25.5 0.1 0.0066 16.8 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain FlaG PF03646.15 CBY31561.1 - 0.046 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 FlaG protein PhoPQ_related PF10142.9 CBY31562.1 - 1.5e-59 201.5 1.6 3.2e-57 193.9 0.2 2.9 1 1 1 2 2 2 2 PhoPQ-activated pathogenicity-related protein Cas9_b_hairpin PF17893.1 CBY31562.1 - 0.036 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Ax_dynein_light PF10211.9 CBY31563.1 - 0.0026 17.8 0.1 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Axonemal dynein light chain Bromodomain PF00439.25 CBY31565.1 - 1.2e-71 236.8 14.3 1.2e-21 76.5 0.3 5.8 6 0 0 6 6 6 4 Bromodomain BAH PF01426.18 CBY31565.1 - 2.4e-18 66.1 0.3 6e-18 64.9 0.3 1.7 1 0 0 1 1 1 1 BAH domain HMG_box PF00505.19 CBY31565.1 - 2.5e-12 47.0 0.6 6.4e-12 45.7 0.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY31565.1 - 9.3e-12 45.4 0.3 3e-11 43.7 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CBY31565.1 - 0.023 14.7 0.0 0.089 12.8 0.0 2.0 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF3461 PF11944.8 CBY31565.1 - 0.09 12.9 0.7 0.82 9.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) WD40 PF00400.32 CBY31566.1 - 2.8e-39 132.4 15.9 1.2e-06 29.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Beta-TrCP_D PF12125.8 CBY31566.1 - 4.9e-16 58.3 0.9 1e-15 57.3 0.9 1.6 1 0 0 1 1 1 1 D domain of beta-TrCP ANAPC4_WD40 PF12894.7 CBY31566.1 - 3e-11 43.5 0.6 0.034 14.4 0.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY31566.1 - 6.3e-09 35.6 0.1 7.5e-05 22.2 0.0 2.7 1 1 1 3 3 3 3 WD40-like domain F-box-like PF12937.7 CBY31566.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 CBY31566.1 - 6.6e-06 26.1 0.2 0.34 11.0 0.0 4.2 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBY31566.1 - 1.1e-05 24.3 3.3 0.96 8.0 0.0 4.6 2 2 2 4 4 4 2 Nucleoporin Nup120/160 120_Rick_ant PF12574.8 CBY31566.1 - 0.00029 20.1 0.1 0.14 11.3 0.0 2.2 1 1 1 2 2 2 2 120 KDa Rickettsia surface antigen F-box PF00646.33 CBY31566.1 - 0.0016 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.11 CBY31566.1 - 0.024 13.4 1.5 1.6 7.4 0.0 3.7 1 1 2 4 4 4 0 Nup133 N terminal like DUF5046 PF16465.5 CBY31566.1 - 0.088 12.2 0.3 1.4 8.3 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 CBY31566.1 - 0.14 11.8 0.1 1.2 8.7 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain Invas_SpaK PF03519.14 CBY31566.1 - 0.16 12.0 0.4 2 8.6 0.1 2.7 2 1 1 3 3 3 0 Invasion protein B family AAA_5 PF07728.14 CBY31567.1 - 2.6e-96 319.0 0.0 1.8e-35 122.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY31567.1 - 9.5e-09 35.9 3.5 0.1 13.0 0.0 5.7 3 2 2 5 5 5 2 AAA ATPase domain AAA_3 PF07726.11 CBY31567.1 - 8e-07 29.0 0.0 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBY31567.1 - 2.8e-06 26.9 0.1 1.3 8.4 0.0 4.6 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI CbbQ_C PF08406.10 CBY31567.1 - 3.2e-06 27.3 0.2 0.005 17.1 0.2 2.8 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_2 PF07724.14 CBY31567.1 - 1.8e-05 24.9 0.0 0.14 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBY31567.1 - 6.5e-05 23.4 0.0 1.1 9.7 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY31567.1 - 6.8e-05 23.2 1.3 0.28 11.4 0.0 4.2 3 2 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CBY31567.1 - 0.00062 19.9 0.1 5 7.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain MCM PF00493.23 CBY31567.1 - 0.0035 16.5 0.0 0.024 13.7 0.0 2.4 3 0 0 3 3 3 1 MCM P-loop domain RsgA_GTPase PF03193.16 CBY31567.1 - 0.0044 16.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 CBY31567.1 - 0.015 15.0 0.0 4.2 7.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 CBY31567.1 - 0.016 15.4 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY31567.1 - 0.023 15.2 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 CBY31567.1 - 0.027 14.2 0.2 23 4.7 0.0 3.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBY31567.1 - 0.039 14.5 0.3 10 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CBY31567.1 - 0.15 11.3 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_8 PF12780.7 CBY31567.1 - 0.18 11.1 0.5 8.9 5.5 0.0 3.3 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 NACHT PF05729.12 CBY31567.1 - 0.18 11.7 0.5 34 4.3 0.0 3.9 4 1 0 4 4 4 0 NACHT domain PQQ_2 PF13360.6 CBY31568.1 - 1.9e-08 34.2 0.0 0.0039 16.8 0.0 3.1 2 2 1 3 3 3 3 PQQ-like domain AMP-binding PF00501.28 CBY31568.1 - 0.018 13.7 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme PQQ_3 PF13570.6 CBY31568.1 - 0.02 15.4 0.0 2.6 8.7 0.0 3.3 2 0 0 2 2 2 0 PQQ-like domain PP-binding PF00550.25 CBY31568.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF4506 PF14958.6 CBY31568.1 - 0.17 11.4 1.0 0.48 9.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4506) Ank_2 PF12796.7 CBY31571.1 - 1.4e-88 291.6 48.5 9.6e-17 61.4 4.4 15.1 7 5 10 17 17 17 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY31571.1 - 5.6e-72 237.2 33.4 1.5e-10 41.4 1.5 17.3 11 4 6 17 17 17 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY31571.1 - 6.6e-52 172.9 38.3 9.3e-07 29.0 2.4 17.2 13 3 4 17 17 17 12 Ankyrin repeats (many copies) Ank PF00023.30 CBY31571.1 - 4.6e-47 156.5 62.7 1.3e-05 25.4 0.1 22.2 24 0 0 24 24 24 11 Ankyrin repeat Ank_3 PF13606.6 CBY31571.1 - 1.2e-42 138.9 39.3 0.00014 22.0 0.2 24.1 27 0 0 27 27 27 10 Ankyrin repeat PARP_reg PF02877.14 CBY31571.1 - 2.4e-17 63.3 0.1 5.4e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CBY31571.1 - 3.9e-09 36.4 0.2 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 WGR domain PARP PF00644.20 CBY31571.1 - 0.00061 19.4 0.1 0.00061 19.4 0.1 3.1 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF484 PF04340.12 CBY31572.1 - 0.0049 16.6 0.0 0.52 10.0 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function, DUF484 Prok-E2_C PF14459.6 CBY31572.1 - 0.022 14.9 0.1 0.68 10.1 0.0 3.0 4 0 0 4 4 4 0 Prokaryotic E2 family C Ntox24 PF15529.6 CBY31572.1 - 0.044 14.1 0.0 4.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial toxin 24 OrsD PF12013.8 CBY31572.1 - 0.13 12.7 2.9 2.2 8.8 0.4 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 CBY31573.1 - 0.14 12.7 0.2 0.14 12.7 0.2 6.0 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 CBY31573.1 - 4.5 7.2 9.9 8.2 6.4 0.4 4.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Paired_CXXCH_1 PF09699.10 CBY31573.1 - 6.7 6.5 12.0 0.11 12.3 0.5 3.5 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) MepB PF08877.10 CBY31575.1 - 0.017 14.9 1.0 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 MepB protein KH_8 PF17903.1 CBY31575.1 - 0.092 12.8 0.1 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Krr1 KH1 domain YlbE PF14003.6 CBY31576.1 - 0.012 16.0 0.9 0.029 14.8 0.9 1.7 1 0 0 1 1 1 0 YlbE-like protein DUF4062 PF13271.6 CBY31576.1 - 0.14 12.6 0.7 0.73 10.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4062) MRPL52 PF18699.1 CBY31576.1 - 0.19 11.9 6.2 1.3 9.2 3.5 2.5 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Thioredoxin_6 PF13848.6 CBY31577.1 - 3.7e-29 102.0 1.0 1.7e-28 99.8 0.2 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CBY31577.1 - 7.6e-08 32.3 0.2 1.9e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 CBY31577.1 - 0.0062 16.5 0.3 0.021 14.7 0.1 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBY31577.1 - 0.0074 16.7 0.5 0.023 15.2 0.5 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY31577.1 - 0.044 13.1 0.2 0.077 12.3 0.2 1.4 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glyco_transf_43 PF03360.16 CBY31577.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 43 HIP1_clath_bdg PF16515.5 CBY31578.1 - 0.0062 17.1 7.3 0.011 16.3 7.3 1.4 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Rx_N PF18052.1 CBY31578.1 - 0.025 14.9 2.4 0.056 13.7 2.4 1.6 1 0 0 1 1 1 0 Rx N-terminal domain DELLA PF12041.8 CBY31578.1 - 0.14 12.1 2.1 6 6.8 0.0 2.9 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal RP-C_C PF11800.8 CBY31578.1 - 0.62 10.1 8.3 1.1 9.3 8.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Cob_adeno_trans PF01923.18 CBY31578.1 - 0.96 9.6 4.0 1.1 9.4 2.7 1.6 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DASH_Spc19 PF08287.11 CBY31578.1 - 1.2 9.0 9.9 0.85 9.5 7.6 1.8 2 0 0 2 2 2 0 Spc19 Spc24 PF08286.11 CBY31578.1 - 1.3 9.3 7.4 3 8.1 7.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 CBY31578.1 - 2.2 7.1 13.1 3.2 6.6 13.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TACC_C PF05010.14 CBY31579.1 - 0.00058 19.7 8.6 0.00058 19.7 8.6 4.7 3 1 0 4 4 4 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 CBY31579.1 - 0.002 18.7 6.4 0.002 18.7 6.4 6.5 2 2 4 6 6 6 3 Initiation control protein YabA DUF3800 PF12686.7 CBY31579.1 - 0.014 16.0 1.0 7.3 7.3 1.0 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF812 PF05667.11 CBY31579.1 - 0.015 14.3 2.3 0.015 14.3 2.3 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 CBY31579.1 - 0.015 15.4 11.8 0.015 15.4 11.8 5.1 2 1 3 5 5 5 0 Tropomyosin like Sec34 PF04136.15 CBY31579.1 - 0.019 14.9 1.5 0.019 14.9 1.5 5.5 4 2 3 7 7 7 0 Sec34-like family DUF4352 PF11611.8 CBY31579.1 - 0.037 14.3 2.9 0.095 13.0 2.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Filament PF00038.21 CBY31579.1 - 1.1 8.8 63.1 0.14 11.7 39.6 3.5 2 2 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 CBY31579.1 - 5 7.2 72.4 2.8 8.0 10.7 5.1 1 1 3 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Homeodomain PF00046.29 CBY31581.1 - 1.2e-19 69.9 12.7 2.4e-19 68.9 12.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY31581.1 - 0.012 15.5 2.3 0.025 14.5 2.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 CBY31581.1 - 0.077 12.5 0.3 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF4148 PF13663.6 CBY31581.1 - 0.14 12.4 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PAP2_3 PF14378.6 CBY31582.1 - 0.15 11.8 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 PAP2 superfamily DUF3450 PF11932.8 CBY31583.1 - 0.0073 15.6 1.7 0.01 15.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 CBY31583.1 - 0.012 15.6 4.1 0.012 15.6 4.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Ax_dynein_light PF10211.9 CBY31583.1 - 0.022 14.7 5.5 0.038 13.9 5.5 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain ABC_tran_CTD PF16326.5 CBY31583.1 - 0.028 14.7 5.3 0.071 13.4 5.3 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain DHR10 PF18595.1 CBY31583.1 - 0.055 13.5 8.3 0.14 12.2 8.3 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TSC22 PF01166.18 CBY31583.1 - 0.15 12.4 7.3 0.13 12.6 4.3 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Tnp_22_trimer PF17489.2 CBY31583.1 - 0.33 10.9 4.3 0.24 11.4 1.1 2.5 2 1 0 2 2 2 0 L1 transposable element trimerization domain SlyX PF04102.12 CBY31583.1 - 0.39 11.4 3.5 0.81 10.3 3.5 1.6 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 CBY31583.1 - 0.84 9.4 5.0 0.77 9.6 3.2 1.8 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 CBY31583.1 - 0.95 8.5 7.3 1.4 8.0 7.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Shugoshin_N PF07558.11 CBY31583.1 - 0.98 9.3 4.7 1.5 8.7 0.9 2.5 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 CBY31583.1 - 1.2 9.3 10.5 0.28 11.3 5.6 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Cast PF10174.9 CBY31584.1 - 3.6e-05 22.2 2.3 3.8e-05 22.2 2.3 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Laminin_I PF06008.14 CBY31584.1 - 0.0055 16.5 1.5 0.0061 16.3 1.5 1.1 1 0 0 1 1 1 1 Laminin Domain I Ribonuc_2-5A PF06479.12 CBY31584.1 - 0.017 15.3 0.4 0.019 15.1 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease 2-5A DGF-1_C PF11040.8 CBY31584.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ctr PF04145.15 CBY31585.1 - 0.016 15.8 1.5 0.016 15.8 1.5 2.6 1 1 1 2 2 2 0 Ctr copper transporter family MAP17 PF15807.5 CBY31585.1 - 0.034 14.4 1.7 0.034 14.4 1.7 2.9 3 1 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 CBY31585.1 - 0.059 14.3 0.8 0.059 14.3 0.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 CBY31585.1 - 0.23 11.1 8.2 0.54 9.9 1.0 2.5 2 0 0 2 2 2 0 FAM176 family CLN3 PF02487.17 CBY31585.1 - 1.7 7.6 5.4 0.35 9.9 0.6 2.0 2 0 0 2 2 2 0 CLN3 protein MLANA PF14991.6 CBY31585.1 - 6.3 7.1 6.3 0.72 10.2 0.7 2.3 2 1 0 2 2 2 0 Protein melan-A CLCA PF08434.11 CBY31586.1 - 3.8e-12 46.1 9.6 1.1e-07 31.4 0.4 2.7 2 1 1 3 3 3 2 Calcium-activated chloride channel N terminal Chordopox_A33R PF05966.12 CBY31586.1 - 0.059 12.7 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Hepsin-SRCR PF09272.10 CBY31586.1 - 0.14 12.7 0.4 0.48 11.0 0.1 2.0 2 0 0 2 2 2 0 Hepsin, SRCR domain COesterase PF00135.28 CBY31587.1 - 1.5e-96 324.4 3.0 1.7e-48 165.8 1.2 2.1 2 0 0 2 2 2 2 Carboxylesterase family Zona_pellucida PF00100.23 CBY31587.1 - 6.1e-18 65.5 2.7 1.2e-17 64.6 2.7 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain Glyco_transf_4 PF13439.6 CBY31587.1 - 0.044 13.8 0.0 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Ig_3 PF13927.6 CBY31588.1 - 1.7e-08 34.9 7.5 0.016 15.8 0.3 6.3 5 2 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 CBY31588.1 - 1.1e-06 28.8 1.8 2.1 8.7 0.1 4.8 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.16 CBY31588.1 - 2.7e-05 24.2 0.8 11 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.15 CBY31588.1 - 0.00028 21.2 0.5 4.5 7.7 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ig PF00047.25 CBY31588.1 - 0.00028 21.0 2.7 14 5.9 0.0 5.5 4 1 0 4 4 4 1 Immunoglobulin domain Ig_4 PF16680.5 CBY31588.1 - 0.044 14.0 0.3 3.9 7.8 0.0 3.5 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain PK PF00224.21 CBY31588.1 - 0.06 12.2 0.1 0.097 11.5 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF4073 PF13285.6 CBY31588.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Trypsin PF00089.26 CBY31589.1 - 2e-41 142.2 0.6 3.2e-41 141.6 0.6 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY31589.1 - 0.00041 21.3 0.0 0.00084 20.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain TSP_1 PF00090.19 CBY31589.1 - 0.0044 17.2 2.3 0.0044 17.2 2.3 3.6 4 0 0 4 4 4 1 Thrombospondin type 1 domain Trefoil PF00088.18 CBY31589.1 - 0.011 15.6 8.3 0.011 15.6 8.3 4.1 3 0 0 3 3 3 0 Trefoil (P-type) domain CD20 PF04103.15 CBY31590.1 - 0.053 13.6 1.9 0.069 13.2 0.1 1.9 2 0 0 2 2 2 0 CD20-like family DUF308 PF03729.13 CBY31590.1 - 0.12 12.7 5.0 0.17 12.2 5.0 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) COPI_assoc PF08507.10 CBY31590.1 - 0.21 11.6 2.5 6.6 6.8 2.5 2.2 1 1 0 1 1 1 0 COPI associated protein MAR_sialic_bdg PF10564.9 CBY31591.1 - 2.9e-164 533.6 66.0 3.2e-19 68.8 0.2 11.6 12 0 0 12 12 12 10 Sialic-acid binding micronemal adhesive repeat CCDC23 PF15674.5 CBY31591.1 - 3.6e-05 23.7 8.3 21 5.2 0.3 7.9 9 0 0 9 9 9 1 Coiled-coil domain-containing protein 23 EF-hand_9 PF14658.6 CBY31591.1 - 0.031 14.6 0.0 11 6.5 0.0 4.3 5 0 0 5 5 5 0 EF-hand domain Frigida PF07899.11 CBY31591.1 - 0.094 12.0 3.6 21 4.2 0.0 5.1 7 0 0 7 7 7 0 Frigida-like protein DDHD PF02862.17 CBY31591.1 - 0.26 11.4 5.9 1.1 9.3 3.2 2.3 2 0 0 2 2 2 0 DDHD domain Tim54 PF11711.8 CBY31591.1 - 4.2 6.1 9.8 2 7.1 2.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Trypsin PF00089.26 CBY31592.1 - 8.3e-13 48.6 0.2 1.1e-12 48.3 0.2 1.1 1 0 0 1 1 1 1 Trypsin Gal-3-0_sulfotr PF06990.11 CBY31593.1 - 5e-28 98.1 3.4 7.8e-28 97.5 1.4 2.2 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 CBY31593.1 - 3.3e-10 39.9 9.4 8.8e-08 32.0 2.4 3.9 2 2 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY31593.1 - 2.2e-06 28.2 4.6 0.001 19.5 0.1 3.7 3 1 0 4 4 4 2 Sulfotransferase family DSPn PF14671.6 CBY31595.1 - 0.081 13.4 2.7 0.31 11.5 2.7 1.8 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half zf-HC5HC2H_2 PF13832.6 CBY31596.1 - 7.8e-34 116.1 11.0 7.8e-34 116.1 11.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY31596.1 - 3.7e-26 91.2 6.2 3.7e-26 91.2 6.2 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 CBY31596.1 - 2.4e-20 72.4 0.5 7.5e-20 70.8 0.5 1.9 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 CBY31596.1 - 2.4e-14 52.6 2.4 2.4e-14 52.6 2.4 2.9 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 CBY31596.1 - 2.4e-10 41.0 2.2 2.4e-10 41.0 2.2 3.3 3 1 0 3 3 2 1 Enhancer of polycomb-like PWWP PF00855.17 CBY31596.1 - 2.7e-10 40.5 0.0 3.3e-09 37.0 0.0 3.0 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 CBY31596.1 - 1.2e-07 31.5 12.0 1.2e-07 31.5 12.0 3.8 4 0 0 4 4 4 2 PHD-finger zf-C2H2 PF00096.26 CBY31596.1 - 0.0022 18.3 0.1 0.0022 18.3 0.1 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type Glyco_hydro_38N PF01074.22 CBY31596.1 - 0.06 12.7 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 N-terminal domain zf-C2H2_4 PF13894.6 CBY31596.1 - 0.58 11.2 0.1 0.58 11.2 0.1 3.9 6 0 0 6 6 3 0 C2H2-type zinc finger ADK_lid PF05191.14 CBY31596.1 - 1.1 9.2 5.7 0.51 10.4 1.5 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid Hydrolase_4 PF12146.8 CBY31598.1 - 4e-39 134.3 0.0 4.6e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY31598.1 - 5.2e-08 32.9 0.0 6.9e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY31598.1 - 1.4e-05 25.8 0.0 2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY31598.1 - 0.0077 15.9 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 CBY31598.1 - 0.098 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family BIV_Env PF05858.12 CBY31598.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) LIDHydrolase PF10230.9 CBY31598.1 - 0.18 11.3 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Na_K-ATPase PF00287.18 CBY31599.1 - 3.8e-54 183.8 0.0 1.2e-28 100.2 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain Neur_chan_memb PF02932.16 CBY31600.1 - 1.2e-64 218.6 21.7 1.6e-53 182.3 17.4 2.1 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY31600.1 - 2.3e-55 187.4 1.0 2.9e-55 187.0 1.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Homeodomain PF00046.29 CBY31601.1 - 9.8e-16 57.4 17.9 7.4e-11 41.7 0.4 4.4 5 0 0 5 5 5 2 Homeodomain EcoRII-N PF09217.10 CBY31601.1 - 0.00069 19.4 1.0 7.2 6.3 0.0 3.5 3 0 0 3 3 3 2 Restriction endonuclease EcoRII, N-terminal Homez PF11569.8 CBY31601.1 - 0.028 13.9 1.3 8.7 5.9 0.1 3.4 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez DUF4817 PF16087.5 CBY31601.1 - 0.061 13.1 0.4 4.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) Homeobox_KN PF05920.11 CBY31601.1 - 0.078 12.9 1.2 0.59 10.1 1.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain CBFD_NFYB_HMF PF00808.23 CBY31601.1 - 0.34 11.2 3.7 15 6.0 0.2 3.7 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trans_reg_C PF00486.28 CBY31601.1 - 2.7 8.2 4.5 14 5.9 0.1 3.2 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal MORN PF02493.20 CBY31602.1 - 3.1e-13 48.8 14.0 2e-05 24.2 0.7 5.4 5 0 0 5 5 5 4 MORN repeat SM-ATX PF14438.6 CBY31602.1 - 0.061 13.5 0.1 3.4 7.9 0.1 2.5 1 1 1 2 2 2 0 Ataxin 2 SM domain MIG-14_Wnt-bd PF06664.12 CBY31603.1 - 0.00043 19.6 3.9 0.00043 19.6 3.9 1.6 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion MLANA PF14991.6 CBY31603.1 - 0.016 15.4 0.4 0.056 13.7 0.0 2.0 3 0 0 3 3 3 0 Protein melan-A DUF3961 PF13106.6 CBY31603.1 - 0.17 11.5 3.4 0.61 9.8 3.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Synaptobrevin PF00957.21 CBY31603.1 - 0.21 11.4 2.1 6.1 6.7 0.6 2.7 2 0 0 2 2 2 0 Synaptobrevin Pho86 PF11124.8 CBY31603.1 - 0.23 10.9 2.9 0.49 9.8 2.9 1.5 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 UPF0114 PF03350.16 CBY31603.1 - 0.43 10.8 5.2 1.9 8.7 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein family, UPF0114 DUF2207 PF09972.9 CBY31603.1 - 0.78 8.4 6.0 19 3.8 6.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) WTF PF03303.13 CBY31603.1 - 1.2 8.8 7.4 0.71 9.6 5.3 1.6 1 1 0 1 1 1 0 WTF protein SGL PF08450.12 CBY31605.1 - 0.054 13.1 0.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Defensin_big PF14862.6 CBY31606.1 - 0.51 10.7 3.4 0.85 10.0 2.7 1.7 1 1 0 1 1 1 0 Big defensin Cg6151-P PF10233.9 CBY31607.1 - 4e-09 36.8 7.8 5.4e-09 36.4 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Tmemb_40 PF10160.9 CBY31607.1 - 0.0058 16.1 2.8 0.0068 15.9 2.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF4133 PF13571.6 CBY31607.1 - 1 9.7 6.7 6.4 7.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Galactosyl_T PF01762.21 CBY31608.1 - 3.3e-16 59.7 0.0 2e-15 57.1 0.0 1.9 1 1 0 1 1 1 1 Galactosyltransferase TTL PF03133.15 CBY31609.1 - 5.3e-45 153.8 1.1 7e-45 153.4 1.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY31609.1 - 0.00025 20.4 0.2 0.0061 15.8 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY31609.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp WAC_Acf1_DNA_bd PF10537.9 CBY31609.1 - 0.092 13.3 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal FlgM PF04316.13 CBY31610.1 - 0.003 17.9 0.1 0.0071 16.7 0.1 1.7 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM MMS22L_N PF14910.6 CBY31610.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal BPL_N PF09825.9 CBY31610.1 - 0.24 10.5 1.9 0.26 10.3 1.9 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal TSP_1 PF00090.19 CBY31611.1 - 7.2e-05 22.9 16.1 0.0015 18.7 4.5 3.3 3 1 0 3 3 3 2 Thrombospondin type 1 domain PQQ PF01011.21 CBY31612.1 - 0.00037 20.3 0.4 0.0069 16.3 0.2 3.1 2 0 0 2 2 2 1 PQQ enzyme repeat Sushi PF00084.20 CBY31612.1 - 4 8.1 7.8 0.76 10.4 2.0 3.0 3 0 0 3 3 3 0 Sushi repeat (SCR repeat) rve PF00665.26 CBY31614.1 - 1.6e-17 63.8 0.0 2e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY31614.1 - 8.4e-17 61.0 0.2 1.9e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVP PF00077.20 CBY31614.1 - 1.2e-06 28.8 0.0 3.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CBY31614.1 - 4.3e-05 24.1 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY31614.1 - 9.4e-05 22.9 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CBY31614.1 - 0.0033 17.2 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CBY31614.1 - 0.026 14.7 0.5 0.099 12.9 0.1 2.2 2 0 0 2 2 2 0 H2C2 zinc finger DUF4988 PF16378.5 CBY31614.1 - 0.052 13.2 0.2 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function EF-hand_7 PF13499.6 CBY31615.1 - 9.9e-18 64.4 7.1 3.6e-11 43.4 3.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY31615.1 - 1.4e-14 52.4 14.9 7.2e-06 25.2 2.3 4.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CBY31615.1 - 1.4e-13 49.5 6.4 1.6e-06 27.6 0.2 4.0 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY31615.1 - 9e-12 44.7 12.8 4.4e-09 36.0 1.4 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY31615.1 - 2.4e-11 43.8 0.9 6.2e-06 26.4 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY31615.1 - 6.5e-06 25.4 8.2 3.5e-05 23.1 0.6 3.5 3 0 0 3 3 3 1 EF hand DUF1456 PF07308.13 CBY31615.1 - 0.013 15.8 0.9 6.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) UPF0154 PF03672.13 CBY31615.1 - 0.053 13.6 0.2 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 CBY31615.1 - 0.072 13.4 0.4 0.5 10.8 0.1 2.4 1 1 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY31615.1 - 0.072 13.4 0.9 0.13 12.6 0.2 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PMBR PF09373.10 CBY31615.1 - 0.16 12.2 0.0 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat UBA_4 PF14555.6 CBY31616.1 - 4.4e-12 45.6 0.1 5.1e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CBY31616.1 - 0.032 13.9 1.1 1.7 8.3 0.2 2.1 1 1 1 2 2 2 0 TAP C-terminal domain DUF3089 PF11288.8 CBY31618.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Acyltransferase PF01553.21 CBY31619.1 - 4.5e-08 32.8 0.0 7.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase EGF PF00008.27 CBY31620.1 - 0.00068 19.9 20.9 0.11 12.9 8.2 3.1 2 0 0 2 2 2 2 EGF-like domain AAA_32 PF13654.6 CBY31620.1 - 0.7 8.6 7.1 1.1 8.0 7.1 1.2 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 CBY31620.1 - 2.3 8.7 38.7 0.24 11.8 12.9 3.2 3 0 0 3 3 3 0 EGF-like domain AIG2_2 PF13772.6 CBY31621.1 - 0.1 13.0 0.2 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 AIG2-like family Phospholip_A2_1 PF00068.19 CBY31624.1 - 1.3e-14 54.6 9.6 1.3e-14 54.6 9.6 2.0 2 0 0 2 2 2 1 Phospholipase A2 Ion_trans_2 PF07885.16 CBY31625.1 - 1.3e-31 108.4 12.1 3e-17 62.3 1.8 4.0 4 0 0 4 4 4 3 Ion channel Ion_trans PF00520.31 CBY31625.1 - 0.0015 17.8 8.4 0.0017 17.6 4.3 2.6 1 1 1 2 2 2 1 Ion transport protein IRK PF01007.20 CBY31625.1 - 0.071 12.9 1.9 0.43 10.4 0.2 2.8 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain Ac76 PF05814.11 CBY31625.1 - 0.63 10.1 6.8 0.35 10.9 0.2 2.8 2 0 0 2 2 2 0 Orf76 (Ac76) Ig_3 PF13927.6 CBY31626.1 - 3.6e-20 72.3 0.0 7e-15 55.4 0.1 2.3 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY31626.1 - 3.4e-14 52.7 0.3 1.9e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY31626.1 - 8.2e-14 51.7 0.0 2.8e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY31626.1 - 6.7e-10 39.0 0.1 3.4e-07 30.3 0.0 3.2 2 2 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY31626.1 - 1.2e-05 25.4 0.0 0.00051 20.2 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin V-set domain Podoplanin PF05808.11 CBY31626.1 - 0.0014 18.8 0.1 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Podoplanin C2-set_2 PF08205.12 CBY31626.1 - 0.028 14.5 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain TIM21 PF08294.11 CBY31626.1 - 0.054 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 TIM21 Ig_6 PF18452.1 CBY31626.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF5326 PF17260.2 CBY31626.1 - 0.59 10.3 7.8 0.099 12.8 4.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Adeno_E3_CR2 PF02439.15 CBY31626.1 - 7.7 6.4 8.1 17 5.2 8.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4490 PF14892.6 CBY31627.1 - 0.0047 17.0 0.9 0.012 15.7 0.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4490) Pes-10 PF07149.11 CBY31627.1 - 0.058 12.5 4.6 0.075 12.1 4.6 1.1 1 0 0 1 1 1 0 Pes-10 ASC PF00858.24 CBY31628.1 - 2.4e-35 122.4 9.7 2.8e-35 122.2 9.7 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel LIM PF00412.22 CBY31629.1 - 2.8e-25 88.3 34.8 3.8e-11 43.0 8.8 3.3 3 0 0 3 3 3 3 LIM domain zf-rbx1 PF12678.7 CBY31631.1 - 1.8e-14 53.7 8.1 2.3e-14 53.4 8.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY31631.1 - 5.3e-11 42.4 4.4 6.4e-11 42.2 4.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY31631.1 - 0.0048 17.2 11.4 0.0098 16.2 11.4 1.7 1 1 0 1 1 1 1 Ring finger domain IRK_C PF17655.1 CBY31631.1 - 0.05 13.2 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain PHD PF00628.29 CBY31631.1 - 0.055 13.4 7.8 0.084 12.8 7.8 1.5 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CBY31631.1 - 0.062 13.5 6.1 0.12 12.6 6.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain gp32 PF08804.10 CBY31631.1 - 0.1 12.6 0.3 0.14 12.2 0.3 1.2 1 0 0 1 1 1 0 gp32 DNA binding protein like zf-RING_UBOX PF13445.6 CBY31631.1 - 0.28 11.2 8.1 0.62 10.1 8.1 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY31631.1 - 0.33 10.9 10.1 0.59 10.0 8.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY31631.1 - 2.6 8.0 11.1 13 5.8 11.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY31631.1 - 3.1 7.5 11.7 7.6 6.2 11.7 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 CBY31632.1 - 2.3e-44 151.8 0.0 2.8e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31632.1 - 8.1e-20 71.2 0.0 1.1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2362 PF10154.9 CBY31634.1 - 0.0032 16.5 2.7 0.0047 15.9 2.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) Topoisom_I_N PF02919.15 CBY31634.1 - 0.27 10.7 4.0 0.53 9.7 4.0 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment GEMIN8 PF15348.6 CBY31634.1 - 1.4 9.1 12.6 2.2 8.5 12.6 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Forkhead PF00250.18 CBY31635.1 - 3.5e-37 126.5 0.8 1.1e-36 125.0 0.8 1.9 1 0 0 1 1 1 1 Forkhead domain DUF4678 PF15727.5 CBY31635.1 - 0.22 10.8 3.3 0.34 10.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) Galactosyl_T PF01762.21 CBY31636.1 - 1.1e-17 64.4 0.0 1.7e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Oxidored_q3 PF00499.20 CBY31636.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PEPcase_2 PF14010.6 CBY31636.1 - 0.057 11.9 0.1 0.14 10.6 0.0 1.5 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase Adeno_terminal PF02459.15 CBY31637.1 - 0.083 11.3 1.7 0.1 10.9 1.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein ATP_synt_H PF05493.13 CBY31638.1 - 0.64 10.5 3.6 0.3 11.6 1.7 1.4 2 0 0 2 2 2 0 ATP synthase subunit H AF-4 PF05110.13 CBY31639.1 - 0.016 13.3 0.3 0.02 13.0 0.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SecE PF00584.20 CBY31639.1 - 0.83 9.6 0.0 0.83 9.6 0.0 3.0 3 1 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Molybdopterin PF00384.22 CBY31640.1 - 4.1e-61 207.3 0.0 1e-59 202.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CBY31640.1 - 1.5e-20 73.0 0.5 3e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CBY31640.1 - 5.6e-17 61.0 0.3 5.6e-17 61.0 0.3 2.1 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CBY31640.1 - 5.9e-10 39.0 0.6 5.9e-10 39.0 0.6 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 CBY31640.1 - 0.014 15.2 5.1 0.74 9.7 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lyx_isomer PF07385.12 CBY31640.1 - 0.034 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_16 PF13484.6 CBY31640.1 - 0.046 14.7 2.9 18 6.4 2.6 3.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY31640.1 - 0.37 11.0 5.5 2 8.6 5.5 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBY31640.1 - 0.41 11.3 6.1 0.54 10.9 3.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 CBY31640.1 - 1.9 9.1 8.2 0.66 10.6 3.1 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY31640.1 - 5.8 7.4 8.6 21 5.6 8.6 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY31640.1 - 8.8 7.0 8.6 0.83 10.2 3.3 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Sec15 PF04091.12 CBY31642.1 - 3.9e-46 157.9 1.2 3.9e-46 157.9 1.2 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like NPF PF16601.5 CBY31642.1 - 1.6 9.1 12.8 1.5 9.2 6.8 2.2 1 1 1 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif COPIIcoated_ERV PF07970.12 CBY31643.1 - 5.3e-35 121.3 0.5 9.2e-35 120.5 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY31643.1 - 1e-28 99.5 0.1 3.2e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Arfaptin PF06456.13 CBY31644.1 - 7.8e-40 136.8 6.6 1.7e-39 135.8 3.5 2.1 2 0 0 2 2 2 1 Arfaptin-like domain PDZ PF00595.24 CBY31644.1 - 1.8e-09 37.8 0.0 3.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY31644.1 - 2.8e-09 36.7 0.0 1.3e-08 34.5 0.0 2.2 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 CBY31644.1 - 1.8e-05 24.9 0.0 3.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF1013 PF06242.11 CBY31644.1 - 0.0083 16.2 0.5 0.03 14.4 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1013) MFS_1 PF07690.16 CBY31646.1 - 2.3e-52 178.1 33.2 1.3e-49 169.0 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CBY31646.1 - 0.0024 16.2 4.0 0.0024 16.2 4.0 3.0 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Steroid_dh PF02544.16 CBY31646.1 - 0.027 14.5 0.8 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase SepRS_C PF18006.1 CBY31647.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain Troponin PF00992.20 CBY31648.1 - 1.2e-18 67.7 27.0 1.2e-18 67.7 27.0 2.3 1 1 1 2 2 2 2 Troponin Fasciclin PF02469.22 CBY31648.1 - 0.08 13.2 0.2 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Fasciclin domain EBP50_C PF09007.11 CBY31648.1 - 0.22 12.5 5.5 0.35 11.9 5.5 1.3 1 0 0 1 1 1 0 EBP50, C-terminal PMP22_Claudin PF00822.20 CBY31649.1 - 0.0015 18.4 0.4 0.014 15.3 0.4 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DctM PF06808.12 CBY31649.1 - 0.0064 15.4 0.4 0.0088 14.9 0.4 1.1 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component L_HMGIC_fpl PF10242.9 CBY31649.1 - 0.0084 16.3 0.3 2.1 8.5 0.0 2.4 2 1 0 2 2 2 2 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY31649.1 - 0.014 15.1 3.9 0.29 10.9 3.9 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Trypan_PARP PF05887.11 CBY31649.1 - 0.039 13.9 10.4 0.048 13.6 2.8 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3439 PF11921.8 CBY31650.1 - 6.8e-05 22.8 43.6 0.0061 16.5 4.7 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3439) Hyphal_reg_CWP PF11765.8 CBY31650.1 - 0.0084 15.1 2.3 0.23 10.4 0.1 2.1 2 0 0 2 2 2 2 Hyphally regulated cell wall protein N-terminal Mucin PF01456.17 CBY31650.1 - 0.0099 15.9 42.2 0.43 10.6 6.7 3.3 3 0 0 3 3 3 3 Mucin-like glycoprotein Amino_oxidase PF01593.24 CBY31651.1 - 4.5e-09 36.1 0.0 5.8e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Prenylcys_lyase PF07156.14 CBY31651.1 - 0.0032 16.6 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase TSP_1 PF00090.19 CBY31652.1 - 3.7e-76 251.1 196.8 1.4e-08 34.8 9.5 15.5 14 1 0 14 14 14 13 Thrombospondin type 1 domain Glyco_hydro_9 PF00759.19 CBY31652.1 - 2.9e-37 129.1 0.4 4.1e-37 128.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 EGF_CA PF07645.15 CBY31652.1 - 1.7e-09 37.7 8.8 1.7e-09 37.7 8.8 7.7 6 1 1 7 7 7 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY31652.1 - 3.4e-05 24.0 37.1 0.00026 21.1 8.1 6.5 7 0 0 7 7 7 3 EGF domain cEGF PF12662.7 CBY31652.1 - 0.0001 22.1 1.3 0.0001 22.1 1.3 5.4 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.27 CBY31652.1 - 0.00011 22.5 3.5 0.00011 22.5 3.5 6.4 6 0 0 6 6 6 2 EGF-like domain Kelch_6 PF13964.6 CBY31652.1 - 0.00013 22.2 0.0 0.37 11.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif hEGF PF12661.7 CBY31652.1 - 7.8 7.3 34.8 0.04 14.6 0.7 6.5 5 0 0 5 5 5 0 Human growth factor-like EGF Lipase PF00151.19 CBY31653.1 - 4.9e-74 249.6 0.0 6.2e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 CBY31653.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAX PF00292.18 CBY31654.1 - 4.5e-39 133.2 0.6 9.9e-39 132.1 0.4 1.6 2 0 0 2 2 2 1 'Paired box' domain Homeodomain PF00046.29 CBY31654.1 - 1.9e-19 69.2 0.5 1.9e-19 69.2 0.5 3.0 4 0 0 4 4 4 1 Homeodomain Homeobox_KN PF05920.11 CBY31654.1 - 0.0002 21.2 0.1 0.00059 19.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CBY31654.1 - 0.00027 20.6 0.1 0.0037 17.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 CBY31654.1 - 0.0051 17.4 1.2 0.061 13.9 0.0 2.9 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 CBY31654.1 - 0.0065 16.5 0.1 0.031 14.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix PHA_synth_III_E PF09712.10 CBY31654.1 - 0.041 13.0 4.7 0.032 13.3 2.7 1.8 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) XRN1_D2_D3 PF18334.1 CBY31654.1 - 0.06 13.6 0.0 7 6.9 0.0 2.6 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain GlgS PF08971.11 CBY31654.1 - 0.18 11.8 0.2 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 Glycogen synthesis protein TNFR_c6 PF00020.18 CBY31655.1 - 0.12 12.8 0.4 0.16 12.4 0.4 1.4 1 1 0 1 1 1 0 TNFR/NGFR cysteine-rich region SNF PF00209.18 CBY31656.1 - 2.3e-201 670.0 32.5 2.7e-201 669.8 32.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family SMN PF06003.12 CBY31657.1 - 9.6e-10 38.2 0.2 9.6e-10 38.2 0.2 2.1 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 CBY31657.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Tudor domain DUF1325 PF07039.11 CBY31657.1 - 0.0015 18.6 1.1 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 SGF29 tudor-like domain SspH PF08141.12 CBY31657.1 - 0.079 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DUF2368 PF10166.9 CBY31657.1 - 0.74 9.4 5.5 0.11 12.1 1.7 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Com_YlbF PF06133.11 CBY31657.1 - 5.7 7.6 10.9 0.51 11.0 0.6 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA OLF PF02191.16 CBY31658.1 - 1.6e-83 280.1 5.2 2.4e-83 279.5 5.2 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain tRNA_anti-codon PF01336.25 CBY31659.1 - 4.8e-06 26.5 0.1 7.8e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Bin3 PF06859.12 CBY31660.1 - 1.5e-38 131.7 0.0 3.3e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 CBY31660.1 - 2.1e-13 50.3 0.0 4e-09 36.4 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 CBY31660.1 - 7.1e-12 45.9 0.0 2.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBY31660.1 - 5.2e-11 42.7 0.0 7.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY31660.1 - 5.3e-11 43.1 0.0 1.9e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CBY31660.1 - 4.3e-10 40.1 0.0 7e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.19 CBY31660.1 - 5.9e-06 26.2 0.0 6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CBY31660.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 CBY31660.1 - 2.9e-05 24.0 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY31660.1 - 5.1e-05 22.7 0.0 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CBY31660.1 - 0.00011 21.7 0.0 0.00044 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Spermine_synth PF01564.17 CBY31660.1 - 0.001 18.5 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_32 PF13679.6 CBY31660.1 - 0.0015 18.6 0.1 0.0037 17.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 CBY31660.1 - 0.0025 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa CMAS PF02353.20 CBY31660.1 - 0.0033 16.7 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 CBY31660.1 - 0.0095 15.4 0.4 0.036 13.5 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase DUF43 PF01861.16 CBY31660.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain UPF0020 PF01170.18 CBY31660.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CheR PF01739.18 CBY31660.1 - 0.064 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pik1 PF11522.8 CBY31660.1 - 0.36 10.8 1.3 0.82 9.7 0.4 2.0 2 0 0 2 2 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 HA2 PF04408.23 CBY31661.1 - 2.6e-19 69.5 0.0 6.6e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY31661.1 - 3.6e-15 56.3 0.0 2.1e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBY31661.1 - 2.1e-07 31.2 0.0 4.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY31661.1 - 9.1e-06 25.5 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBY31661.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY31661.1 - 0.0003 21.1 1.0 0.0012 19.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY31661.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBY31661.1 - 0.016 15.7 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Herpes_UL37_2 PF07413.11 CBY31661.1 - 0.053 12.8 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 AIG1 PF04548.16 CBY31661.1 - 0.084 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ResIII PF04851.15 CBY31661.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4558 PF15104.6 CBY31662.1 - 0.43 10.7 9.8 0.84 9.7 9.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) CLASP_N PF12348.8 CBY31663.1 - 3.7e-08 33.2 0.5 9e-08 32.0 0.3 1.7 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 CBY31663.1 - 0.14 12.7 0.1 6.9 7.3 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region FAM76 PF16046.5 CBY31664.1 - 1.4 8.2 22.6 2.9 7.2 22.6 1.5 1 0 0 1 1 1 0 FAM76 protein F-box_4 PF15966.5 CBY31666.1 - 0.0039 17.1 0.1 0.0095 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box PRANC PF09372.10 CBY31666.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Phospholip_A2_1 PF00068.19 CBY31667.1 - 1.2e-10 41.8 5.1 1.2e-10 41.8 5.1 1.8 2 0 0 2 2 2 1 Phospholipase A2 zf-TRAF_2 PF15965.5 CBY31669.1 - 2.1e-07 31.3 2.2 2.9e-07 30.8 2.2 1.2 1 0 0 1 1 1 1 TRAF-like zinc-finger IL1_propep PF02394.16 CBY31669.1 - 0.011 16.7 0.1 0.016 16.1 0.1 1.5 1 1 0 1 1 1 0 Interleukin-1 propeptide zf-TRAF PF02176.18 CBY31669.1 - 1.5 9.6 8.5 2.6 8.8 7.0 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger fn3 PF00041.21 CBY31670.1 - 2.8e-85 280.7 63.4 6.1e-06 26.5 0.0 25.9 27 0 0 27 27 27 18 Fibronectin type III domain PKD_channel PF08016.12 CBY31670.1 - 2.7e-51 174.6 1.2 7.1e-51 173.2 1.2 1.6 1 0 0 1 1 1 1 Polycystin cation channel REJ PF02010.15 CBY31670.1 - 4.1e-34 118.2 4.1 2.1e-24 86.1 0.0 4.7 6 0 0 6 6 6 2 REJ domain PLAT PF01477.23 CBY31670.1 - 9.9e-16 58.4 2.2 2.9e-14 53.6 0.0 4.2 4 0 0 4 4 4 1 PLAT/LH2 domain Pur_ac_phosph_N PF16656.5 CBY31670.1 - 5.1e-09 36.6 34.0 0.034 14.7 0.4 12.6 15 0 0 15 15 15 4 Purple acid Phosphatase, N-terminal domain GPS PF01825.21 CBY31670.1 - 0.00034 21.1 0.9 0.00034 21.1 0.9 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Interfer-bind PF09294.10 CBY31670.1 - 0.057 13.7 22.6 13 6.1 0.0 11.6 14 0 0 14 14 14 0 Interferon-alpha/beta receptor, fibronectin type III DUF4945 PF16303.5 CBY31670.1 - 8.1 6.4 9.9 6.4 6.7 0.1 5.4 5 1 1 6 6 6 0 Domain of unknown function (DUF4945) Ion_trans PF00520.31 CBY31671.1 - 0.0071 15.6 1.6 0.012 14.9 1.6 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY31671.1 - 0.0081 14.9 2.2 0.013 14.2 2.2 1.3 1 0 0 1 1 1 1 Polycystin cation channel CBM_14 PF01607.24 CBY31672.1 - 2.5e-10 40.3 8.9 2.5e-10 40.3 8.9 5.6 5 0 0 5 5 5 1 Chitin binding Peritrophin-A domain Serglycin PF04360.12 CBY31672.1 - 6.3e-05 23.0 13.9 0.13 12.2 0.4 3.6 3 0 0 3 3 3 3 Serglycin Utp14 PF04615.13 CBY31672.1 - 0.31 9.6 12.1 0.57 8.7 12.1 1.3 1 0 0 1 1 1 0 Utp14 protein GABP-alpha PF11620.8 CBY31673.1 - 0.13 12.4 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 GA-binding protein alpha chain GYF_2 PF14237.6 CBY31674.1 - 1.8e-13 50.1 0.4 4.8e-13 48.7 0.2 1.9 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 CBY31674.1 - 2.1e-06 27.7 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arm PF00514.23 CBY31674.1 - 5.1e-05 23.2 7.1 0.023 14.8 0.3 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.6 CBY31674.1 - 0.00052 20.1 1.5 0.083 13.0 0.4 2.9 3 0 0 3 3 3 2 Exocyst complex component SEC3 N-terminal PIP2 binding PH KIAA1430 PF13879.6 CBY31674.1 - 0.37 11.6 2.4 0.86 10.4 0.1 2.5 2 0 0 2 2 2 0 KIAA1430 homologue HECT PF00632.25 CBY31675.1 - 9.2e-79 265.1 0.7 1.1e-78 264.8 0.0 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF3337 PF11816.8 CBY31675.1 - 0.011 15.7 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) WD40 PF00400.32 CBY31677.1 - 2e-26 91.7 15.2 0.0043 17.8 0.0 10.4 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY31677.1 - 1.3e-18 67.1 1.4 0.00047 20.4 0.0 7.5 5 3 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY31677.1 - 8.8e-06 25.7 0.1 0.16 11.8 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A NUP214 PF16755.5 CBY31677.1 - 0.00016 21.0 0.0 0.026 13.7 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PD40 PF07676.12 CBY31677.1 - 0.022 14.7 0.0 3.6 7.7 0.0 3.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBY31677.1 - 0.027 13.4 0.4 8.6 5.2 0.0 3.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY31677.1 - 0.039 12.6 0.0 1.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 CBY31677.1 - 0.065 12.6 0.0 1.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal LVIVD PF08309.11 CBY31677.1 - 0.42 10.0 2.8 0.74 9.2 0.2 2.7 3 0 0 3 3 3 0 LVIVD repeat Filament PF00038.21 CBY31678.1 - 0.0018 17.9 5.3 0.0022 17.6 5.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein LRRFIP PF09738.9 CBY31678.1 - 0.6 9.5 11.6 0.63 9.5 8.3 2.0 1 1 1 2 2 2 0 LRRFIP family Seryl_tRNA_N PF02403.22 CBY31679.1 - 0.0037 17.5 3.7 0.0037 17.5 3.7 4.8 2 1 4 6 6 6 1 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.11 CBY31679.1 - 0.004 17.0 3.1 0.004 17.0 3.1 3.9 4 0 0 4 4 4 1 Shugoshin N-terminal coiled-coil region Filament PF00038.21 CBY31679.1 - 0.0078 15.8 34.3 0.005 16.5 30.4 2.1 2 0 0 2 2 2 1 Intermediate filament protein Fib_alpha PF08702.10 CBY31679.1 - 0.009 16.2 15.0 0.009 16.2 15.0 3.2 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CBY31679.1 - 0.071 13.5 29.2 0.23 11.9 0.5 5.8 4 2 1 6 6 6 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 CBY31679.1 - 0.29 11.7 43.6 0.82 10.2 18.0 4.0 1 1 2 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 CBY31679.1 - 0.59 10.3 46.0 1.1 9.4 30.6 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CBY31679.1 - 1.5 8.9 46.7 0.12 12.4 10.0 4.0 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.13 CBY31679.1 - 2.7 8.5 34.0 0.18 12.2 3.1 5.1 2 1 2 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DUF745 PF05335.13 CBY31679.1 - 3.7 7.2 22.1 0.016 14.9 8.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF745) GIT_CC PF16559.5 CBY31679.1 - 3.9 7.4 18.4 0.44 10.4 0.6 4.3 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 CBY31679.1 - 6.2 6.9 43.4 1.6 8.8 0.2 3.8 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 CBY31679.1 - 7.3 5.4 47.2 0.059 12.2 22.8 3.7 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF4407 PF14362.6 CBY31679.1 - 7.5 5.8 26.9 4 6.7 13.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CBY31679.1 - 7.8 6.6 48.6 1.2 9.2 16.7 4.1 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Lebercilin PF15619.6 CBY31679.1 - 8.3 6.0 52.4 5.2 6.7 35.1 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fungal_TACC PF12709.7 CBY31680.1 - 0.0083 16.5 0.7 0.0083 16.5 0.7 6.1 2 1 6 8 8 8 1 Fungal Transforming acidic coiled-coil (TACC) proteins XhlA PF10779.9 CBY31680.1 - 0.037 14.2 1.3 0.037 14.2 1.3 4.3 4 2 0 4 4 4 0 Haemolysin XhlA Tnp_22_trimer PF17489.2 CBY31680.1 - 0.15 12.1 3.4 0.38 10.7 0.2 2.9 2 0 0 2 2 2 0 L1 transposable element trimerization domain Fez1 PF06818.15 CBY31680.1 - 3.9 7.9 49.1 0.32 11.4 12.6 3.7 1 1 2 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 CBY31680.1 - 4.3 7.4 6.9 4.4 7.3 0.2 3.0 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MBOAT PF03062.19 CBY31681.1 - 1.2e-44 153.2 5.2 2.1e-44 152.3 5.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_T PF00929.24 CBY31682.1 - 8.6e-09 36.1 0.0 1.3e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBY31682.1 - 0.0018 18.0 0.4 0.027 14.2 0.4 2.6 1 1 0 1 1 1 1 3'-5' exonuclease Ig_3 PF13927.6 CBY31683.1 - 1.9e-08 34.8 0.0 8.2e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY31683.1 - 1.5e-07 31.4 0.0 1.5e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CBY31683.1 - 1.5e-06 28.3 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY31683.1 - 0.0016 18.8 0.1 0.067 13.5 0.0 2.9 1 1 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY31683.1 - 0.027 14.6 0.0 0.078 13.2 0.0 1.8 1 0 0 1 1 1 0 Immunoglobulin V-set domain GAS PF13851.6 CBY31685.1 - 0.00014 21.3 10.4 0.00014 21.3 10.4 4.2 1 1 2 4 4 4 1 Growth-arrest specific micro-tubule binding HisKA_3 PF07730.13 CBY31685.1 - 0.00059 20.3 13.3 5.4 7.6 0.1 5.9 4 2 0 5 5 5 2 Histidine kinase DUF948 PF06103.11 CBY31685.1 - 0.014 15.6 28.0 4.8 7.5 0.2 6.2 4 3 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Collagen_mid PF15984.5 CBY31685.1 - 0.054 13.2 0.1 0.2 11.4 0.2 1.9 1 1 1 2 2 2 0 Bacterial collagen, middle region Syntaxin_2 PF14523.6 CBY31685.1 - 0.087 13.2 25.6 0.054 13.9 1.2 5.3 3 3 1 4 4 4 0 Syntaxin-like protein Baculo_PEP_C PF04513.12 CBY31685.1 - 0.43 10.6 21.8 1 9.4 2.0 5.3 3 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CBY31685.1 - 0.58 10.0 47.9 0.42 10.5 14.0 3.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain T3SS_needle_F PF09392.10 CBY31685.1 - 0.81 9.9 0.0 0.81 9.9 0.0 6.5 5 2 1 7 7 7 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF ApoO PF09769.9 CBY31685.1 - 2.4 8.1 13.3 17 5.3 0.0 5.5 4 3 1 6 6 6 0 Apolipoprotein O DUF883 PF05957.13 CBY31685.1 - 3.5 8.3 46.4 0.36 11.5 1.9 6.6 4 3 4 8 8 8 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.11 CBY31685.1 - 5.4 7.6 31.3 4.8 7.8 4.4 5.8 2 2 2 4 4 4 0 Syntaxin 6, N-terminal YtxH PF12732.7 CBY31685.1 - 6.5 7.4 62.7 0.33 11.5 6.2 7.1 3 2 2 5 5 4 0 YtxH-like protein Dynamin_M PF01031.20 CBY31685.1 - 6.9 5.8 12.2 11 5.1 5.0 3.3 1 1 2 3 3 3 0 Dynamin central region ArnB_C PF18677.1 CBY31685.1 - 7 6.8 23.5 3.3 7.9 1.4 4.5 4 0 0 4 4 4 0 Archaellum regulatory network B, C-terminal domain PMC2NT PF08066.12 CBY31685.1 - 7.3 7.4 23.0 2 9.2 0.6 4.8 3 2 2 5 5 5 0 PMC2NT (NUC016) domain AhpC-TSA PF00578.21 CBY31686.1 - 6.1e-35 119.8 0.0 1.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY31686.1 - 1.7e-13 50.5 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY31686.1 - 2.1e-12 46.7 0.1 4.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF563 PF04577.14 CBY31686.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) MFS_1 PF07690.16 CBY31687.1 - 9.3e-25 87.3 35.2 9.3e-25 87.3 35.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY31687.1 - 0.00018 20.0 9.4 0.00035 19.0 8.7 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Nuc_sug_transp PF04142.15 CBY31687.1 - 0.012 14.8 1.5 0.012 14.8 1.5 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter MOSC PF03473.17 CBY31689.1 - 6.7e-19 68.2 0.0 9.6e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CBY31689.1 - 3.6e-17 62.4 0.0 5.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain adh_short PF00106.25 CBY31690.1 - 2.4e-50 170.7 1.0 3.2e-50 170.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY31690.1 - 1.6e-47 162.0 0.2 2e-47 161.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY31690.1 - 8.3e-13 48.6 0.4 1.2e-12 48.1 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBY31690.1 - 1.8e-05 24.8 0.2 2.2e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CBY31690.1 - 0.029 13.8 0.1 0.093 12.2 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CBY31690.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Toxin_TOLIP PF00087.21 CBY31691.1 - 0.024 14.9 0.7 3.7 7.9 0.1 3.3 2 0 0 2 2 2 0 Snake toxin and toxin-like protein Pkinase PF00069.25 CBY31693.1 - 4.4e-08 32.8 0.2 1e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31693.1 - 2.4e-06 27.0 0.4 6e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase I-set PF07679.16 CBY31694.1 - 7.2e-107 349.7 2.7 9.8e-20 70.4 0.0 10.9 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY31694.1 - 2.1e-71 236.5 0.9 1.1e-14 54.7 0.0 10.5 10 0 0 10 10 10 7 Immunoglobulin domain Ig_2 PF13895.6 CBY31694.1 - 1.5e-40 137.4 3.5 6.4e-13 48.8 0.0 8.1 7 1 1 8 8 8 5 Immunoglobulin domain ig PF00047.25 CBY31694.1 - 6.5e-32 109.6 2.5 1.7e-08 34.5 0.0 8.8 9 0 0 9 9 9 4 Immunoglobulin domain V-set PF07686.17 CBY31694.1 - 1.9e-18 66.6 6.8 0.00022 21.3 0.0 10.8 8 5 0 8 8 8 3 Immunoglobulin V-set domain BiPBP_C PF06832.12 CBY31694.1 - 1.8e-12 47.1 0.0 1.8 8.7 0.0 8.4 9 0 0 9 9 9 2 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 CBY31694.1 - 2.5e-10 40.3 6.0 0.055 13.5 0.0 7.2 9 0 0 9 9 9 3 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CBY31694.1 - 2.9e-09 37.2 3.1 1.4 9.4 0.0 8.0 8 1 0 8 8 8 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Izumo-Ig PF16706.5 CBY31694.1 - 2.6e-08 33.8 0.8 0.62 10.2 0.0 5.9 5 1 1 6 6 6 2 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CBY31694.1 - 9.8e-08 32.2 5.4 1.4 9.3 0.0 7.0 7 1 0 7 7 7 3 T-cell surface glycoprotein CD3 delta chain fn3 PF00041.21 CBY31694.1 - 5e-05 23.6 0.0 0.00075 19.8 0.0 3.0 3 0 0 3 3 3 1 Fibronectin type III domain Ig_6 PF18452.1 CBY31694.1 - 0.00063 19.3 0.2 14 5.3 0.1 4.5 4 0 0 4 4 4 1 Immunoglobulin domain I-set PF07679.16 CBY31696.1 - 8.4e-62 205.3 23.7 2.2e-11 43.7 0.1 10.8 11 0 0 11 11 11 9 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY31696.1 - 2.4e-43 146.6 3.1 4.6e-06 27.1 0.0 10.1 10 0 0 10 10 9 8 Immunoglobulin domain ig PF00047.25 CBY31696.1 - 3.2e-25 88.1 12.9 2.3e-06 27.7 0.0 10.6 10 2 0 10 10 10 5 Immunoglobulin domain Ig_2 PF13895.6 CBY31696.1 - 6.8e-17 61.6 2.3 0.14 12.5 0.0 8.4 9 0 0 9 9 9 3 Immunoglobulin domain V-set PF07686.17 CBY31696.1 - 5.5e-14 52.3 2.6 0.25 11.5 0.0 8.4 7 2 0 7 7 7 3 Immunoglobulin V-set domain fn3 PF00041.21 CBY31696.1 - 6.7e-09 36.0 0.0 5.4e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 Fibronectin type III domain Ig_6 PF18452.1 CBY31696.1 - 1.2e-05 24.8 0.0 0.7 9.5 0.0 4.9 5 0 0 5 5 5 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY31696.1 - 0.00051 20.0 0.1 22 5.2 0.0 4.4 4 0 0 4 4 4 0 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CBY31696.1 - 0.0042 17.3 13.5 3.8 7.9 0.1 6.2 7 0 0 7 7 7 1 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 CBY31696.1 - 0.0056 16.9 3.0 20 5.5 0.0 5.7 6 0 0 6 6 6 0 Natural killer cell receptor 2B4 SH3_1 PF00018.28 CBY31696.1 - 0.032 13.8 1.4 0.13 11.9 1.4 2.0 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 CBY31696.1 - 0.096 12.6 0.2 0.32 10.9 0.2 1.9 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 CBY31696.1 - 0.19 11.4 1.0 0.52 10.0 1.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF1307 PF06998.11 CBY31696.1 - 1 9.4 7.1 0.88 9.6 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) Phospholip_A2_1 PF00068.19 CBY31697.1 - 7.2e-15 55.4 7.1 7.2e-15 55.4 7.1 2.0 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY31698.1 - 9.1e-14 51.9 6.5 9.1e-14 51.9 6.5 2.1 2 0 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.25 CBY31699.1 - 4.7e-09 36.0 0.0 7.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31699.1 - 2.7e-07 30.1 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane PF01061.24 CBY31700.1 - 6.6e-15 55.1 9.6 6.6e-15 55.1 9.6 1.7 3 0 0 3 3 3 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBY31700.1 - 0.0009 18.4 9.7 0.0013 18.0 9.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Pkinase PF00069.25 CBY31701.1 - 8e-08 32.0 0.0 2.4e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31701.1 - 4.1e-05 23.0 0.0 8.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2183 PF09949.9 CBY31702.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) B_lectin PF01453.24 CBY31704.1 - 0.086 13.4 0.8 0.78 10.3 0.1 2.6 2 1 1 3 3 3 0 D-mannose binding lectin WD40 PF00400.32 CBY31705.1 - 0.033 15.1 2.6 0.41 11.6 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Prok-E2_E PF14462.6 CBY31706.1 - 0.47 10.3 5.0 0.93 9.3 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E 7tm_1 PF00001.21 CBY31709.1 - 6.1e-22 78.2 14.7 2.5e-18 66.4 9.2 2.7 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY31709.1 - 8.6e-06 25.2 6.3 8.6e-06 25.2 6.3 2.1 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw TMEM154 PF15102.6 CBY31709.1 - 0.26 11.2 0.7 3.2 7.7 0.0 2.4 1 1 1 2 2 2 0 TMEM154 protein family TMEM238 PF15125.6 CBY31709.1 - 1 9.6 5.7 3.1 8.1 0.4 2.7 2 0 0 2 2 2 0 TMEM238 protein family zf-LITAF-like PF10601.9 CBY31709.1 - 1.6 9.1 11.9 13 6.2 0.0 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain APH PF01636.23 CBY31710.1 - 9.5e-19 68.3 0.0 1.8e-18 67.3 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY31710.1 - 5.8e-05 22.8 0.0 0.00019 21.1 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 CBY31710.1 - 0.039 12.8 0.0 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 CBY31710.1 - 0.085 12.4 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family SCAB-PH PF17684.1 CBY31711.1 - 0.14 12.4 1.0 0.31 11.3 1.0 1.6 1 1 0 1 1 1 0 PH domain of plant-specific actin-binding protein RhoGEF PF00621.20 CBY31712.1 - 2.7e-29 102.7 0.8 1.5e-17 64.4 0.2 2.2 2 0 0 2 2 2 2 RhoGEF domain Tam41_Mmp37 PF09139.11 CBY31712.1 - 0.0068 15.9 0.1 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial zf-LITAF-like PF10601.9 CBY31713.1 - 1.4e-14 54.1 20.7 1.8e-14 53.8 20.7 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Phage_integr_3 PF16795.5 CBY31714.1 - 0.027 14.4 1.0 0.041 13.8 1.0 1.2 1 0 0 1 1 1 0 Archaeal phage integrase Oxidored_q2 PF00420.24 CBY31715.1 - 0.021 14.4 2.9 0.033 13.8 0.0 2.6 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7tm_1 PF00001.21 CBY31715.1 - 0.036 13.4 0.2 0.036 13.4 0.2 2.1 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 CBY31715.1 - 0.043 12.6 3.6 0.26 10.0 0.0 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Orf78 PF06024.12 CBY31715.1 - 0.057 13.7 0.0 0.057 13.7 0.0 2.7 3 0 0 3 3 3 0 Orf78 (ac78) DUF3169 PF11368.8 CBY31715.1 - 0.072 12.6 8.6 0.012 15.2 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4500 PF14937.6 CBY31715.1 - 0.15 12.1 0.1 0.39 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF4834 PF16118.5 CBY31715.1 - 0.29 12.1 1.6 1.6 9.7 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CagD PF16567.5 CBY31716.1 - 0.024 14.4 0.3 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Pathogenicity island component CagD Glyco_hydro_130 PF04041.13 CBY31716.1 - 0.036 13.0 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase DUF4897 PF16238.5 CBY31716.1 - 0.074 12.9 0.5 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) RVT_1 PF00078.27 CBY31717.1 - 1.7e-18 67.0 0.0 1.8e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CBY31717.1 - 0.0012 18.5 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBY31717.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Hydrolase_4 PF12146.8 CBY31718.1 - 1.9e-45 155.0 0.0 2.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY31718.1 - 6.2e-17 62.1 0.1 1.9e-10 40.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY31718.1 - 3.3e-12 47.5 0.0 4.8e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CBY31718.1 - 2.2e-06 27.6 0.0 4.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Peptidase_S28 PF05577.12 CBY31718.1 - 1e-05 24.5 0.0 1.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 UPF0227 PF05728.12 CBY31718.1 - 1.3e-05 25.2 0.0 4.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) DLH PF01738.18 CBY31718.1 - 0.0001 21.9 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY31718.1 - 0.00011 21.8 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.13 CBY31718.1 - 0.00079 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CBY31718.1 - 0.0017 18.2 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CBY31718.1 - 0.0023 17.5 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CBY31718.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBY31718.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 CBY31718.1 - 0.034 13.7 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 CBY31718.1 - 0.035 14.1 0.5 0.072 13.0 0.0 1.7 2 0 0 2 2 1 0 Cutinase Thioesterase PF00975.20 CBY31718.1 - 0.038 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 CBY31718.1 - 0.081 12.8 0.0 7.9 6.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.12 CBY31718.1 - 0.12 11.4 0.1 0.3 10.1 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2920 PF11144.8 CBY31718.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF4094 PF13334.6 CBY31719.1 - 0.85 10.1 4.3 12 6.4 4.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) SMN PF06003.12 CBY31720.1 - 1.5e-10 40.8 9.9 2.1e-07 30.5 2.6 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF4537 PF15057.6 CBY31720.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) YqfQ PF14181.6 CBY31720.1 - 0.25 11.5 2.1 0.33 11.1 2.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Rad60-SLD PF11976.8 CBY31721.1 - 1.8e-06 27.7 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY31721.1 - 0.0043 16.8 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Tn7_Tnp_TnsA_C PF08721.11 CBY31721.1 - 0.11 13.2 0.0 0.35 11.5 0.0 1.8 1 1 1 2 2 2 0 TnsA endonuclease C terminal PB1 PF00564.24 CBY31722.1 - 1.7e-08 34.3 0.1 2.8e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 PB1 domain PDZ PF00595.24 CBY31722.1 - 4.8e-08 33.2 0.1 7.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY31722.1 - 8.8e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain DUF1899 PF08953.11 CBY31723.1 - 3.2e-30 103.8 0.0 7.9e-30 102.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CBY31723.1 - 2.8e-22 78.3 0.1 4.8e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CBY31723.1 - 1.2e-11 44.9 4.0 3.2e-06 27.8 0.6 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY31723.1 - 6.2e-10 39.2 0.6 0.06 13.7 0.0 4.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Trimer_CC PF08954.11 CBY31723.1 - 0.0039 16.7 1.9 0.0078 15.7 1.1 1.9 2 0 0 2 2 2 1 Trimerisation motif WHAMM-JMY_N PF15920.5 CBY31723.1 - 0.035 14.0 0.2 0.6 10.0 0.0 2.3 1 1 1 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated Comm PF15957.5 CBY31724.1 - 0.013 15.9 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 0 Commissureless RCR PF12273.8 CBY31724.1 - 0.039 14.6 0.0 0.063 13.9 0.0 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mucin PF01456.17 CBY31724.1 - 0.057 13.4 1.6 0.072 13.1 1.6 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein Nic96 PF04097.14 CBY31725.1 - 2.1e-166 555.0 0.0 2.5e-166 554.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Clathrin PF00637.20 CBY31725.1 - 0.026 14.4 0.0 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Region in Clathrin and VPS Peptidase_M16_M PF16187.5 CBY31725.1 - 0.033 13.5 0.1 0.086 12.1 0.1 1.6 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 ANAPC3 PF12895.7 CBY31725.1 - 0.057 13.6 1.1 0.38 11.0 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBY31725.1 - 0.16 12.8 0.2 67 4.7 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat RAMP4 PF06624.12 CBY31726.1 - 1.2e-25 89.3 0.1 1.3e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Radical_SAM PF04055.21 CBY31727.1 - 1.1e-21 77.9 1.2 4.7e-21 75.9 0.3 2.6 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 CBY31727.1 - 2.4e-17 62.8 0.0 1.4e-16 60.3 0.0 2.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Fib_alpha PF08702.10 CBY31727.1 - 0.0066 16.6 7.5 0.0066 16.6 7.5 10.3 3 2 6 10 10 10 3 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 CBY31727.1 - 0.0077 16.4 7.0 0.0077 16.4 7.0 10.3 1 1 7 8 8 8 1 Uncharacterised protein family (UPF0242) N-terminus TRAM PF01938.20 CBY31727.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 TRAM domain FoP_duplication PF13865.6 CBY31728.1 - 1.8e-23 82.9 35.8 7.8e-17 61.6 19.9 4.7 2 2 2 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 efThoc1 PF11957.8 CBY31729.1 - 3.1e-126 421.9 18.8 3.1e-126 421.9 18.8 1.4 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Death PF00531.22 CBY31729.1 - 2.9e-10 40.2 0.2 9.2e-10 38.6 0.2 1.9 1 0 0 1 1 1 1 Death domain DUF2130 PF09903.9 CBY31729.1 - 0.0011 18.3 1.5 0.0011 18.3 1.5 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2130) DUF2408 PF10303.9 CBY31729.1 - 0.34 11.5 4.4 4.5 7.9 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) zf-B_box PF00643.24 CBY31730.1 - 6.3e-11 42.2 39.6 4.4e-10 39.5 8.8 4.4 4 0 0 4 4 4 2 B-box zinc finger zf-RING_UBOX PF13445.6 CBY31730.1 - 3.1e-05 23.9 0.7 3.1e-05 23.9 0.7 3.8 3 2 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY31730.1 - 5.2e-05 23.5 4.6 5.2e-05 23.5 4.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY31730.1 - 8.7e-05 22.4 8.4 8.7e-05 22.4 8.4 4.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY31730.1 - 0.0021 17.9 4.3 0.0021 17.9 4.3 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY31730.1 - 0.037 14.2 1.4 0.037 14.2 1.4 4.3 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING SUIM_assoc PF16619.5 CBY31730.1 - 1.6 8.8 6.3 6.1 7.0 0.5 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ion_trans PF00520.31 CBY31731.1 - 1.3e-50 172.0 13.7 1.6e-50 171.6 13.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY31731.1 - 1.8e-12 47.0 8.6 2.4e-12 46.7 5.4 2.4 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.22 CBY31731.1 - 1.9e-11 44.2 0.7 4.3e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain PKD_channel PF08016.12 CBY31731.1 - 0.00042 19.1 2.0 0.00042 19.1 2.0 2.0 1 1 1 2 2 2 1 Polycystin cation channel Sld5 PF05916.11 CBY31731.1 - 0.027 14.9 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 GINS complex protein WAK PF08488.11 CBY31731.1 - 0.065 13.8 0.2 0.12 12.9 0.2 1.5 1 0 0 1 1 1 0 Wall-associated kinase Sigma_reg_N PF13800.6 CBY31731.1 - 1 9.7 4.3 3.2 8.1 0.1 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal BRD4_CDT PF17105.5 CBY31731.1 - 4.1 7.1 7.0 9.7 5.9 7.0 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 FAM195 PF14799.6 CBY31732.1 - 9.3e-08 32.4 3.6 1.2e-07 32.0 3.6 1.2 1 0 0 1 1 1 1 FAM195 family BDHCT_assoc PF16204.5 CBY31732.1 - 0.13 11.9 6.4 0.17 11.6 0.7 2.6 1 1 2 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein Ank_2 PF12796.7 CBY31733.1 - 1e-32 112.6 0.0 4e-12 46.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY31733.1 - 8.2e-29 99.3 1.5 1.4e-08 34.8 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY31733.1 - 6.8e-26 87.5 0.1 2.5e-06 27.4 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 CBY31733.1 - 2.3e-24 84.7 0.8 2.2e-05 24.7 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 CBY31733.1 - 1.2e-22 79.9 0.4 4.9e-06 27.0 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Pur_ac_phosph_N PF16656.5 CBY31733.1 - 0.088 13.4 0.1 0.24 12.0 0.1 1.6 1 1 1 2 2 2 0 Purple acid Phosphatase, N-terminal domain V-set PF07686.17 CBY31735.1 - 0.022 14.9 0.1 0.037 14.2 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin V-set domain Pkinase PF00069.25 CBY31736.1 - 2.2e-52 178.0 0.0 1.4e-51 175.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31736.1 - 1.2e-35 123.1 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY31736.1 - 2.3e-06 26.6 0.0 3.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY31736.1 - 0.00086 18.7 0.1 0.0013 18.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY31736.1 - 0.0014 18.0 0.1 0.0043 16.4 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBY31736.1 - 0.003 16.6 0.4 0.0059 15.6 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CBY31736.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_S30 PF01577.16 CBY31736.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease APH PF01636.23 CBY31736.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 CBY31737.1 - 0.01 15.6 0.0 1.8 8.4 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_2 PF01497.18 CBY31739.1 - 0.025 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Ig_3 PF13927.6 CBY31740.1 - 1.1e-34 118.8 4.4 3.1e-08 34.1 0.0 6.0 6 0 0 6 6 6 5 Immunoglobulin domain I-set PF07679.16 CBY31740.1 - 1.4e-25 89.2 3.5 3.5e-08 33.4 0.0 6.4 5 3 0 5 5 5 4 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY31740.1 - 5.5e-25 87.5 0.0 0.00016 22.0 0.0 5.7 5 0 0 5 5 5 4 Immunoglobulin domain V-set PF07686.17 CBY31740.1 - 1.2e-16 60.8 0.4 7.6e-10 38.9 0.0 5.7 5 1 1 6 6 6 2 Immunoglobulin V-set domain ig PF00047.25 CBY31740.1 - 4.4e-16 58.8 1.7 0.00024 21.2 0.0 6.2 5 2 0 5 5 5 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY31740.1 - 3.9e-08 33.2 9.5 3.4e-06 27.0 0.0 4.5 5 0 0 5 5 5 2 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CBY31740.1 - 0.0043 17.1 0.1 1.6 8.8 0.1 3.5 4 1 0 4 4 4 1 C17orf99 Ig domain Methyltransf_25 PF13649.6 CBY31741.1 - 2.6e-07 31.3 0.0 8.7e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY31741.1 - 3.1e-07 30.3 0.1 1.1e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY31741.1 - 0.0001 22.9 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY31741.1 - 0.0096 16.6 0.1 0.042 14.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY31741.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FtsJ PF01728.19 CBY31741.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase zf-MYST PF17772.1 CBY31742.1 - 0.078 12.6 3.0 0.67 9.6 0.3 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2 PF00096.26 CBY31742.1 - 0.32 11.5 0.2 0.32 11.5 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sulfotransfer_3 PF13469.6 CBY31743.1 - 8.8e-08 32.8 0.2 9.8e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY31743.1 - 3.3e-06 26.8 1.6 2.1e-05 24.1 1.6 2.2 1 1 0 1 1 1 1 Sulfotransferase domain SH3BP5 PF05276.14 CBY31744.1 - 3.1e-12 46.8 15.6 4.6e-12 46.2 15.6 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) SPATA24 PF15175.6 CBY31744.1 - 0.013 15.4 17.2 0.13 12.2 0.1 3.1 1 1 0 2 2 2 0 Spermatogenesis-associated protein 24 Peptidase_S48 PF03574.15 CBY31744.1 - 0.016 15.4 0.3 0.041 14.1 0.2 1.7 1 1 0 1 1 1 0 Peptidase family S48 Citrate_synt PF00285.21 CBY31744.1 - 0.038 13.1 1.2 0.14 11.2 0.4 1.9 1 1 1 2 2 2 0 Citrate synthase, C-terminal domain FAM194 PF14977.6 CBY31744.1 - 0.049 13.0 1.3 0.079 12.3 1.3 1.3 1 0 0 1 1 1 0 FAM194 protein DUF5601 PF18151.1 CBY31744.1 - 0.12 12.8 1.8 6.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) DUF910 PF06014.11 CBY31744.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF910) FapA PF03961.13 CBY31744.1 - 0.49 8.9 10.6 0.61 8.6 10.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MerR-DNA-bind PF09278.11 CBY31744.1 - 1.2 9.7 4.6 5.7 7.6 1.7 2.6 1 1 1 2 2 2 0 MerR, DNA binding Syntaxin-6_N PF09177.11 CBY31744.1 - 3.9 8.1 11.5 2.4 8.8 6.5 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CLCA PF08434.11 CBY31745.1 - 1.4e-21 77.1 4.1 7.4e-20 71.4 4.1 2.4 1 1 0 1 1 1 1 Calcium-activated chloride channel N terminal VWA PF00092.28 CBY31745.1 - 1.2e-10 41.9 0.0 4.8e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY31745.1 - 1.2e-07 32.3 0.0 3.6e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY31745.1 - 0.00082 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF1194 PF06707.11 CBY31745.1 - 0.073 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) Lectin_C PF00059.21 CBY31745.1 - 6.8 7.5 8.4 0.49 11.2 1.3 2.7 2 1 0 2 2 2 0 Lectin C-type domain Aldedh PF00171.22 CBY31746.1 - 3.1e-132 441.4 0.2 3.9e-132 441.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M19 PF01244.21 CBY31746.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF3692 PF12469.8 CBY31746.1 - 0.15 12.3 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein HLH PF00010.26 CBY31747.1 - 5.4e-11 42.3 0.9 5.4e-11 42.3 0.9 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CENP-N PF05238.13 CBY31747.1 - 0.85 8.8 7.6 0.87 8.8 3.2 2.3 2 1 1 3 3 3 0 Kinetochore protein CHL4 like HLH PF00010.26 CBY31748.1 - 2.9e-10 39.9 0.6 2.9e-10 39.9 0.6 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Innexin PF00876.18 CBY31750.1 - 0.00088 18.7 1.9 0.002 17.5 1.9 1.7 1 1 0 1 1 1 1 Innexin DUF3671 PF12420.8 CBY31750.1 - 0.41 10.7 0.0 0.41 10.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function DHHC PF01529.20 CBY31752.1 - 8.8e-35 119.7 15.4 8.8e-35 119.7 15.4 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase MqsA_antitoxin PF15731.5 CBY31752.1 - 0.14 12.3 1.0 0.39 10.8 0.7 1.8 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FYVE PF01363.21 CBY31752.1 - 6.9 6.9 13.7 14 5.9 13.2 1.7 1 1 0 1 1 1 0 FYVE zinc finger PGK PF00162.19 CBY31753.1 - 3.1e-148 493.8 2.0 3.5e-148 493.6 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 CBY31753.1 - 0.16 11.3 0.1 27 4.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3530) MMgT PF10270.9 CBY31754.1 - 3.6e-10 40.1 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter zf-C2H2 PF00096.26 CBY31755.1 - 1.5e-06 28.3 15.6 0.0015 18.9 3.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31755.1 - 4.7e-05 23.9 9.4 0.0054 17.5 1.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY31755.1 - 8.1e-05 22.8 6.5 0.072 13.4 0.7 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY31755.1 - 0.0082 16.5 0.2 0.0082 16.5 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY31755.1 - 0.011 16.0 3.1 0.13 12.7 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBY31755.1 - 0.014 16.1 3.5 0.12 13.0 0.1 2.9 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats RXT2_N PF08595.11 CBY31755.1 - 0.082 12.9 1.3 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-C2H2_11 PF16622.5 CBY31755.1 - 0.16 11.7 3.8 0.47 10.3 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type 4HBT PF03061.22 CBY31756.1 - 2.8e-09 37.2 0.0 0.0031 17.8 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily DUF5532 PF17673.1 CBY31756.1 - 0.067 13.3 0.4 8.3 6.5 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Zip PF02535.22 CBY31757.1 - 4.1e-27 95.3 16.7 5.3e-23 81.8 4.6 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter LETM1 PF07766.13 CBY31758.1 - 3.6e-81 272.5 0.8 6.3e-81 271.7 0.8 1.4 1 0 0 1 1 1 1 LETM1-like protein EF-hand_1 PF00036.32 CBY31758.1 - 0.0002 20.7 0.3 0.00055 19.3 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CBY31758.1 - 0.00071 19.0 0.8 0.0019 17.6 0.8 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY31758.1 - 0.00096 19.6 1.4 0.027 14.9 0.4 3.0 2 1 0 2 2 2 1 EF-hand domain pair DUF1053 PF06327.14 CBY31758.1 - 0.013 16.0 1.9 0.062 13.9 1.7 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) EF-hand_6 PF13405.6 CBY31758.1 - 0.016 15.1 0.8 0.087 12.8 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 CBY31758.1 - 0.15 11.9 0.1 0.44 10.4 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair DUF745 PF05335.13 CBY31758.1 - 6.4 6.5 8.7 1.3 8.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Tim17 PF02466.19 CBY31759.1 - 7.2e-18 65.0 5.8 9.7e-18 64.6 5.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CAF1 PF04857.20 CBY31760.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Ras PF00071.22 CBY31762.1 - 2.4e-60 202.8 1.7 3.1e-60 202.5 1.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY31762.1 - 3.3e-32 111.2 1.4 6.7e-32 110.2 1.4 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY31762.1 - 4.4e-15 55.6 0.3 5.9e-15 55.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY31762.1 - 2e-05 24.1 0.1 3.2e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBY31762.1 - 7.5e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY31762.1 - 9.8e-05 22.4 0.3 0.00018 21.6 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY31762.1 - 0.00063 19.3 0.3 0.0013 18.3 0.2 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBY31762.1 - 0.0019 17.8 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY31762.1 - 0.0023 17.9 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBY31762.1 - 0.014 15.7 0.0 0.027 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CBY31762.1 - 0.035 13.8 1.0 0.085 12.6 1.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CBY31762.1 - 0.049 12.9 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin DBP10CT PF08147.12 CBY31762.1 - 0.056 13.7 1.2 0.07 13.4 0.1 1.7 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Tfb2_C PF18307.1 CBY31762.1 - 0.079 13.4 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain DUF2757 PF10955.8 CBY31762.1 - 0.12 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) FAD-SLDH PF12318.8 CBY31762.1 - 0.26 11.3 2.2 16 5.5 0.3 2.4 2 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF3890 PF13029.6 CBY31762.1 - 0.48 10.9 2.3 7.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) CAP PF00188.26 CBY31763.1 - 2.8e-07 31.4 0.2 9.2e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-HIT PF04438.16 CBY31763.1 - 4.8 7.1 10.4 0.94 9.4 1.2 3.4 3 0 0 3 3 3 0 HIT zinc finger UCH PF00443.29 CBY31764.1 - 7.3e-46 156.8 0.0 1.2e-45 156.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY31764.1 - 6.1e-16 58.9 2.0 7.8e-10 38.8 0.1 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.29 CBY31764.1 - 0.37 10.7 3.7 0.37 10.7 1.2 2.2 2 0 0 2 2 2 0 PHD-finger CarbpepA_inh PF02977.15 CBY31764.1 - 1.2 9.0 5.1 0.98 9.3 0.9 2.4 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Cofilin_ADF PF00241.20 CBY31765.1 - 5.2e-28 97.3 0.0 6.5e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoU_methylas_C PF12105.8 CBY31766.1 - 0.1 12.3 0.5 11 5.9 0.1 2.6 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal SecA_SW PF07516.13 CBY31766.1 - 0.18 11.8 4.3 0.27 11.2 4.3 1.4 1 1 0 1 1 1 0 SecA Wing and Scaffold domain CorA PF01544.18 CBY31766.1 - 1.3 8.3 4.3 13 5.0 0.1 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Mod_r PF07200.13 CBY31767.1 - 0.0054 16.8 0.2 0.0054 16.8 0.2 2.6 2 1 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein COG5 PF10392.9 CBY31767.1 - 0.048 13.8 0.7 0.048 13.8 0.7 2.4 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Imm9 PF15587.6 CBY31767.1 - 0.074 12.7 0.9 5.3 6.7 0.4 2.6 2 1 0 2 2 2 0 Immunity protein 9 Laminin_I PF06008.14 CBY31767.1 - 0.13 12.0 10.5 0.26 11.0 3.5 2.2 1 1 1 2 2 2 0 Laminin Domain I Sulfatase_C PF14707.6 CBY31767.1 - 0.13 13.0 0.5 0.13 13.0 0.5 2.2 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase SecA_SW PF07516.13 CBY31767.1 - 0.41 10.7 10.1 0.99 9.4 10.1 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain T2SSF PF00482.23 CBY31767.1 - 0.77 9.7 2.2 3.2 7.7 0.4 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Fzo_mitofusin PF04799.13 CBY31767.1 - 1.4 8.5 4.1 1.3 8.5 0.6 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 CBY31767.1 - 2.4 8.8 5.1 0.78 10.4 0.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TipAS PF07739.13 CBY31767.1 - 3.2 8.3 5.5 3 8.4 1.2 2.8 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4404 PF14357.6 CBY31767.1 - 5.3 7.7 11.3 19 6.0 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) FAM76 PF16046.5 CBY31767.1 - 6.5 6.0 12.4 13 5.0 12.4 1.4 1 1 0 1 1 1 0 FAM76 protein Trypsin PF00089.26 CBY31768.1 - 1.7e-129 430.2 9.0 8.1e-42 143.5 0.0 5.4 5 0 0 5 5 5 5 Trypsin DUF1986 PF09342.11 CBY31768.1 - 1.1e-15 58.0 0.5 0.006 17.0 0.1 5.9 5 1 1 6 6 6 4 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY31768.1 - 1.3e-06 29.4 0.2 0.001 20.0 0.0 4.4 5 0 0 5 5 5 1 Trypsin-like peptidase domain Cellulase-like PF12876.7 CBY31768.1 - 0.044 13.1 0.5 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF1664 PF07889.12 CBY31769.1 - 0.00025 21.1 7.9 0.091 12.8 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 CBY31769.1 - 0.025 13.4 6.7 0.033 13.1 6.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 CBY31769.1 - 0.039 14.6 3.1 0.42 11.3 0.7 2.1 2 0 0 2 2 2 0 SlyX Bcr-Abl_Oligo PF09036.10 CBY31769.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Flagellin_C PF00700.21 CBY31769.1 - 0.12 12.8 4.3 0.084 13.2 1.6 1.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DUF16 PF01519.16 CBY31769.1 - 0.37 11.3 10.8 2.4 8.7 9.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 CBY31769.1 - 1.5 9.0 9.0 2 8.6 9.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 CBY31769.1 - 3.5 6.9 9.2 8.1 5.7 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MCM PF00493.23 CBY31770.1 - 1.6e-96 321.7 0.2 2.4e-96 321.2 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY31770.1 - 2.4e-31 108.2 1.9 5e-31 107.2 1.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY31770.1 - 3.9e-25 88.1 0.2 9.6e-25 86.8 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 CBY31770.1 - 3.7e-21 75.4 0.1 8.6e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CBY31770.1 - 1.1e-14 54.8 3.0 5.3e-14 52.7 0.5 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY31770.1 - 1e-07 31.6 0.1 1.5e-05 24.5 0.0 2.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY31770.1 - 6.4e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY31770.1 - 0.0001 22.2 0.0 0.00056 19.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY31770.1 - 0.00034 20.4 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain MMR_HSR1 PF01926.23 CBY31770.1 - 0.17 12.0 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Orn_Arg_deC_N PF02784.16 CBY31771.1 - 6.7e-42 143.6 0.0 8.5e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBY31771.1 - 2.2e-11 43.8 0.0 4.3e-11 42.9 0.0 1.6 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Laminin_N PF00055.17 CBY31775.1 - 1.7e-08 34.4 0.0 6.7e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Laminin N-terminal (Domain VI) 7tm_2 PF00002.24 CBY31776.1 - 7.6e-43 146.6 17.5 9.9e-43 146.2 17.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PAP_central PF04928.17 CBY31776.1 - 0.17 10.8 0.6 0.25 10.3 0.6 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain UAA PF08449.11 CBY31777.1 - 8.8e-09 35.0 5.9 1e-08 34.8 5.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY31777.1 - 7.8e-07 28.7 2.1 9.7e-07 28.4 2.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY31777.1 - 0.00016 21.8 6.4 0.00019 21.6 6.4 1.2 1 0 0 1 1 1 1 EamA-like transporter family DnaJ PF00226.31 CBY31778.1 - 1.4e-27 95.5 0.9 2.9e-27 94.6 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Trigger_C PF05698.14 CBY31779.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF3553 PF12073.8 CBY31780.1 - 0.09 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Fis1_TPR_C PF14853.6 CBY31780.1 - 0.096 12.8 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat NYD-SP28 PF14772.6 CBY31781.1 - 2.3e-21 75.7 16.9 2.3e-21 75.7 16.9 5.3 2 2 2 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 CBY31781.1 - 4.7e-07 29.8 2.1 4.7e-07 29.8 2.1 3.9 3 0 0 3 3 3 1 Sperm tail C-terminal domain Lectin_N PF03954.14 CBY31781.1 - 2.9 7.6 27.3 2.5 7.8 4.9 4.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Radial_spoke PF04712.12 CBY31782.1 - 1.6e-08 34.0 0.5 4.6e-06 25.8 0.1 2.3 1 1 0 2 2 2 2 Radial spokehead-like protein XendoU PF09412.10 CBY31783.1 - 6.1e-83 278.1 0.0 6.9e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 CBY31783.1 - 0.0022 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial EndoU nuclease Pkinase PF00069.25 CBY31784.1 - 1.6e-40 139.1 0.0 2.3e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31784.1 - 4.3e-16 59.0 0.0 6.1e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY31784.1 - 4e-10 39.4 0.0 7.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY31784.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY31784.1 - 0.00018 20.4 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY31784.1 - 0.00029 19.9 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY31784.1 - 0.0057 16.3 0.3 0.0088 15.7 0.3 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY31784.1 - 0.026 13.8 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like EGF_CA PF07645.15 CBY31785.1 - 6.9e-07 29.4 3.6 6.9e-07 29.4 3.6 6.7 8 0 0 8 8 8 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY31785.1 - 0.048 13.9 4.8 0.048 13.9 4.8 5.8 5 1 0 5 5 5 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY31785.1 - 0.088 12.9 38.5 0.59 10.2 2.8 6.2 5 2 0 5 5 5 0 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY31785.1 - 0.2 12.0 32.2 2.6 8.4 1.4 5.7 5 0 0 5 5 5 0 Pvs28 EGF domain EGF_3 PF12947.7 CBY31785.1 - 10 6.4 48.3 0.073 13.3 3.2 6.4 5 3 0 5 5 5 0 EGF domain Zona_pellucida PF00100.23 CBY31786.1 - 2.5e-41 142.2 2.9 2.9e-41 142.0 2.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain ATP-gua_Ptrans PF00217.19 CBY31787.1 - 3.1e-78 262.1 0.0 4.1e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY31787.1 - 4.9e-30 103.7 0.0 8.9e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain AdoMet_MTase PF07757.13 CBY31788.1 - 8.1e-41 138.9 0.0 1.4e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CBY31788.1 - 0.0035 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY31788.1 - 0.0092 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CBY31788.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CBY31788.1 - 0.036 14.1 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY31788.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY31788.1 - 0.088 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CBY31788.1 - 0.15 12.7 0.0 0.37 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_114 PF03537.13 CBY31788.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 ANAPC9 PF12856.7 CBY31789.1 - 0.057 13.6 3.9 0.061 13.5 0.8 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 9 MAM1 PF10434.9 CBY31791.1 - 0.24 11.0 0.1 0.24 11.0 0.1 3.8 4 1 1 5 5 5 0 Monopolin complex protein MAM1 ECH_1 PF00378.20 CBY31792.1 - 3.9e-38 131.2 0.0 4.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY31792.1 - 1.8e-11 44.1 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBY31792.1 - 0.0048 16.9 0.1 0.93 9.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 GDP_Man_Dehyd PF16363.5 CBY31793.1 - 4.9e-154 512.7 0.0 5.6e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY31793.1 - 2.2e-70 236.9 0.1 2.7e-70 236.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBY31793.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBY31793.1 - 0.0002 20.6 0.0 0.00044 19.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 CBY31793.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Amdo_NSP PF12475.8 CBY31793.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Amdovirus non-structural protein SH3_9 PF14604.6 CBY31794.1 - 1e-14 54.1 0.0 2.3e-06 27.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CBY31794.1 - 5.6e-08 32.4 0.0 2.7e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY31794.1 - 6.8e-07 28.8 0.1 0.0096 15.5 0.0 3.0 3 1 0 3 3 3 2 SH3 domain bZIP_1 PF00170.21 CBY31794.1 - 0.25 11.4 2.0 1.2 9.2 1.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor zf-C4 PF00105.18 CBY31795.1 - 3.6e-16 59.4 10.1 7.2e-16 58.4 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY31795.1 - 0.072 12.6 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CBY31795.1 - 0.082 13.0 1.9 0.21 11.7 1.9 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Glutaminase PF04960.15 CBY31796.1 - 1.6e-32 112.8 0.0 2.9e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Glutaminase Cas6_N PF17952.1 CBY31796.1 - 0.056 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Cas6 N-terminal domain GST_C_2 PF13410.6 CBY31798.1 - 3.3e-07 30.2 0.0 1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY31798.1 - 0.034 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY31798.1 - 0.056 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LRR_8 PF13855.6 CBY31803.1 - 7.8e-39 131.3 38.0 1.9e-10 40.4 9.9 7.5 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CBY31803.1 - 5.4e-24 83.9 52.6 1.2e-06 28.7 1.9 9.4 5 2 6 11 11 11 9 Leucine Rich repeats (2 copies) PDZ PF00595.24 CBY31803.1 - 5.3e-15 55.5 1.2 9.3e-13 48.3 0.4 2.6 2 0 0 2 2 2 1 PDZ domain LRR_9 PF14580.6 CBY31803.1 - 3.4e-09 36.4 21.2 0.0082 15.7 0.3 5.4 1 1 3 5 5 5 4 Leucine-rich repeat PDZ_6 PF17820.1 CBY31803.1 - 1.4e-07 31.2 0.3 3e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 PDZ domain LRR_5 PF13306.6 CBY31803.1 - 2.1e-06 27.7 1.8 0.0014 18.6 0.0 2.9 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) PDZ_2 PF13180.6 CBY31803.1 - 0.0024 18.1 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain LRR_6 PF13516.6 CBY31803.1 - 0.0026 17.7 22.8 2.1 8.6 1.5 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CBY31803.1 - 0.065 13.8 31.2 12 6.9 1.1 9.3 10 1 0 10 10 10 0 Leucine Rich Repeat Vhr1 PF04001.13 CBY31803.1 - 0.27 11.6 1.9 0.89 9.9 0.2 2.6 2 0 0 2 2 2 0 Transcription factor Vhr1 NRDE-2 PF08424.10 CBY31804.1 - 8.4e-17 61.3 1.3 2.3e-13 50.0 0.2 2.6 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference NRDE-2 PF08424.10 CBY31805.1 - 4.4e-31 108.2 1.0 8e-31 107.4 1.0 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference MIR PF02815.19 CBY31805.1 - 0.18 11.6 1.2 0.3 10.9 0.6 1.5 1 1 0 1 1 1 0 MIR domain DUF1043 PF06295.12 CBY31805.1 - 2 8.5 6.0 0.92 9.5 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) EF-hand_1 PF00036.32 CBY31806.1 - 2.8e-13 48.4 5.2 0.00079 18.8 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY31806.1 - 2.7e-12 46.9 3.2 5.1e-07 30.0 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY31806.1 - 7.8e-11 41.7 7.6 0.0032 17.3 0.2 4.7 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY31806.1 - 2.2e-09 36.5 3.9 0.15 12.1 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY31806.1 - 3.4e-05 23.2 13.4 0.46 10.1 0.1 4.8 5 0 0 5 5 5 3 EF hand Mito_carr PF00153.27 CBY31806.1 - 0.00017 21.5 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein EF-hand_10 PF14788.6 CBY31806.1 - 0.0096 15.8 1.4 3.7 7.5 0.1 3.2 2 1 1 3 3 3 2 EF hand Excalibur PF05901.11 CBY31806.1 - 0.15 12.7 0.4 19 6.0 0.1 2.5 2 0 0 2 2 2 0 Excalibur calcium-binding domain TSP_3 PF02412.18 CBY31806.1 - 2.2 8.1 4.8 20 5.0 0.3 3.2 3 0 0 3 3 3 0 Thrombospondin type 3 repeat Mito_carr PF00153.27 CBY31807.1 - 2.6e-20 72.2 0.1 2.1e-15 56.4 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Thioredoxin_4 PF13462.6 CBY31809.1 - 1.5e-08 35.0 0.0 2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 CBY31809.1 - 5.1e-07 29.7 0.0 0.026 14.3 0.0 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain IpgD PF05925.12 CBY31809.1 - 0.026 13.1 0.1 0.035 12.7 0.1 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD SURF4 PF02077.15 CBY31810.1 - 1.9e-39 135.9 5.0 2.2e-39 135.7 5.0 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY31810.1 - 0.16 12.6 0.1 0.16 12.6 0.1 3.1 2 1 1 3 3 3 0 DoxX Tht1 PF04163.12 CBY31810.1 - 0.22 10.3 3.6 0.31 9.7 3.6 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Peptidase_S8 PF00082.22 CBY31811.1 - 6e-45 153.8 3.8 9.3e-45 153.1 3.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY31811.1 - 2.6e-25 88.3 0.0 1.1e-24 86.2 0.0 2.2 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF3695 PF12494.8 CBY31811.1 - 1.6e-18 66.4 0.2 3e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) S8_pro-domain PF16470.5 CBY31811.1 - 3.4e-07 30.9 0.0 9.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 CBY31811.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family DAGK_acc PF00609.19 CBY31813.1 - 1.7e-47 161.8 0.0 3.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBY31813.1 - 1.8e-24 85.7 0.0 6.4e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain I-set PF07679.16 CBY31815.1 - 1.8e-48 162.5 6.2 7.7e-18 64.3 0.0 7.8 7 0 0 7 7 7 7 Immunoglobulin I-set domain fn3 PF00041.21 CBY31815.1 - 1.2e-34 118.5 0.5 1.3e-11 44.7 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 CBY31815.1 - 5.3e-29 100.6 0.5 1.2e-09 38.6 0.0 7.2 8 0 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CBY31815.1 - 3.1e-16 59.5 0.1 7.7e-07 29.4 0.0 6.0 5 1 1 6 6 6 3 Immunoglobulin domain ig PF00047.25 CBY31815.1 - 1.3e-14 54.1 2.5 5.9e-09 36.0 0.0 5.9 5 1 1 6 6 6 2 Immunoglobulin domain THB PF18362.1 CBY31815.1 - 1.4e-10 40.6 0.2 3.4e-10 39.3 0.2 1.7 1 0 0 1 1 1 1 Tri-helix bundle domain V-set PF07686.17 CBY31815.1 - 6.2e-08 32.8 0.2 0.27 11.4 0.0 6.3 5 1 0 5 5 5 1 Immunoglobulin V-set domain ITI_HC_C PF06668.12 CBY31815.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.9 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus zf-C2H2 PF00096.26 CBY31816.1 - 1.1e-12 47.7 26.4 9.8e-05 22.6 2.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31816.1 - 2.6e-10 40.2 22.4 0.0023 18.6 1.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY31816.1 - 2.9e-10 40.1 8.4 2.6e-06 27.6 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY31816.1 - 7.4e-06 25.8 20.4 0.00012 22.0 0.5 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY31816.1 - 0.0016 18.7 24.5 0.12 12.7 1.1 3.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CBY31816.1 - 0.0077 16.0 1.7 0.19 11.5 0.3 2.6 1 1 1 2 2 2 1 GAGA factor FYVE PF01363.21 CBY31816.1 - 0.01 16.0 6.3 0.01 16.0 6.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-AN1 PF01428.16 CBY31816.1 - 0.012 15.7 17.5 0.091 12.9 4.4 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger zf-met PF12874.7 CBY31816.1 - 0.013 15.9 19.1 0.035 14.5 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY31816.1 - 0.11 12.8 10.9 4.3 7.6 5.8 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2757 PF10955.8 CBY31816.1 - 0.43 10.9 5.9 6.5 7.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2757) Prok-RING_1 PF14446.6 CBY31816.1 - 1 9.3 8.3 12 5.9 0.2 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 XPA_N PF01286.18 CBY31816.1 - 1 9.5 10.1 15 5.7 0.1 3.4 3 0 0 3 3 3 0 XPA protein N-terminal PyrI_C PF02748.15 CBY31816.1 - 2.4 8.1 9.7 5 7.1 0.3 3.4 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_8 PF15909.5 CBY31816.1 - 3.1 8.2 13.5 0.17 12.2 3.9 2.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY31816.1 - 4.6 7.6 20.9 8.4 6.8 0.7 3.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 CBY31816.1 - 7 6.9 8.7 29 4.9 2.5 2.7 2 1 0 2 2 2 0 Zinc ribbon domain Choline_transpo PF04515.12 CBY31817.1 - 4.2e-82 276.0 34.2 4.2e-82 276.0 34.2 2.8 3 0 0 3 3 3 1 Plasma-membrane choline transporter Apo-VLDL-II PF05418.11 CBY31817.1 - 0.013 16.1 0.0 0.043 14.4 0.0 1.8 2 0 0 2 2 2 0 Apovitellenin I (Apo-VLDL-II) CoA_transf_3 PF02515.17 CBY31818.1 - 2.3e-69 234.3 0.0 3.8e-69 233.6 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III FDF PF09532.10 CBY31819.1 - 3.4e-05 24.7 0.9 3.4e-05 24.7 0.9 1.9 2 0 0 2 2 2 1 FDF domain DUF1735 PF08522.10 CBY31819.1 - 0.12 13.0 0.2 0.21 12.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Pkinase PF00069.25 CBY31820.1 - 5.1e-63 212.9 0.0 7.3e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31820.1 - 6.4e-32 110.9 0.0 9.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CBY31820.1 - 1.3e-11 44.8 1.1 3e-11 43.6 0.6 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain Pkinase_fungal PF17667.1 CBY31820.1 - 6.6e-05 21.9 0.0 8.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY31820.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PC-Esterase PF13839.6 CBY31821.1 - 0.0069 16.2 0.0 0.0085 15.9 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RhoGAP PF00620.27 CBY31824.1 - 1.4e-28 99.6 0.0 2.9e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 CBY31824.1 - 1.1e-05 25.2 4.6 2.5e-05 24.0 4.6 1.7 1 1 0 1 1 1 1 BAR domain Tropomyosin_1 PF12718.7 CBY31824.1 - 1.4 9.1 5.7 0.74 10.0 2.3 2.2 2 0 0 2 2 2 0 Tropomyosin like Dyp_perox PF04261.12 CBY31826.1 - 0.12 11.3 0.2 0.14 11.1 0.2 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family zf-C2H2 PF00096.26 CBY31827.1 - 8.9e-15 54.2 51.9 0.002 18.5 3.3 7.7 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31827.1 - 3.3e-14 52.4 52.7 0.00084 20.0 3.2 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY31827.1 - 1e-05 25.7 2.3 1e-05 25.7 2.3 10.1 9 1 1 10 10 10 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 CBY31827.1 - 0.00057 20.2 26.8 0.15 12.4 0.1 5.7 5 2 0 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBY31827.1 - 0.00089 19.9 25.1 0.0035 18.0 0.2 6.2 4 2 2 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CBY31827.1 - 0.0098 16.2 23.9 0.34 11.3 0.3 6.4 7 0 0 7 7 6 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CBY31827.1 - 0.017 15.0 1.2 0.017 15.0 1.2 6.5 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CBY31827.1 - 0.036 13.8 29.8 0.22 11.3 0.0 5.8 6 0 0 6 6 5 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY31827.1 - 0.053 13.5 44.8 0.24 11.4 2.8 7.0 7 0 0 7 7 7 0 C2H2-type zinc finger DUF1178 PF06676.11 CBY31827.1 - 0.099 13.0 8.8 0.16 12.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) zf-met PF12874.7 CBY31827.1 - 0.12 12.8 0.3 0.12 12.8 0.3 7.0 6 1 1 7 7 7 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 CBY31827.1 - 0.27 11.1 20.1 5.7 6.9 0.1 6.2 5 1 1 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.7 CBY31827.1 - 0.5 10.4 23.8 12 6.0 0.3 5.1 4 1 0 4 4 4 0 Double zinc ribbon zf-Di19 PF05605.12 CBY31827.1 - 0.65 10.3 29.2 0.63 10.4 1.0 5.1 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.12 CBY31827.1 - 0.77 8.2 16.7 0.1 11.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF629) DUF2256 PF10013.9 CBY31827.1 - 0.92 9.7 0.0 0.92 9.7 0.0 5.8 7 0 0 7 7 6 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 CBY31827.1 - 0.97 9.9 30.1 1.8 9.1 3.1 6.2 5 3 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 CBY31827.1 - 3.2 8.1 9.1 7.8 6.9 0.6 3.3 3 0 0 3 3 3 0 zinc-finger-containing domain zf-FCS PF06467.14 CBY31827.1 - 6.9 6.7 19.5 6.9 6.7 0.1 5.7 5 1 1 6 6 6 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.9 CBY31827.1 - 8.7 6.5 17.2 29 4.8 0.2 5.2 5 0 0 5 5 5 0 Zinc-finger domain BSD PF03909.17 CBY31828.1 - 5.2e-12 45.6 1.3 1.7e-11 44.0 1.3 1.9 1 0 0 1 1 1 1 BSD domain GPP34 PF05719.11 CBY31829.1 - 4.4e-57 193.4 1.6 6.4e-57 192.9 1.6 1.3 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.20 CBY31830.1 - 7.2e-19 68.4 33.2 2.3e-13 50.6 28.5 2.0 1 1 1 2 2 2 2 Troponin DUF4366 PF14283.6 CBY31830.1 - 0.028 14.5 4.5 0.047 13.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VIT1 PF01988.19 CBY31830.1 - 0.5 10.2 3.1 0.84 9.5 3.1 1.3 1 0 0 1 1 1 0 VIT family ANAPC_CDC26 PF10471.9 CBY31830.1 - 3.7 8.4 14.6 1.9 9.4 1.4 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 RR_TM4-6 PF06459.12 CBY31830.1 - 6.5 6.5 15.9 9 6.0 15.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sugar_tr PF00083.24 CBY31831.1 - 6.4e-23 81.3 18.0 1e-13 51.0 1.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY31831.1 - 5.6e-12 45.2 19.4 5.5e-08 32.1 4.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1440 PF07274.12 CBY31831.1 - 0.0092 16.3 2.3 0.032 14.6 0.1 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF1440) YidC_periplas PF14849.6 CBY31831.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 YidC periplasmic domain Ribonuc_2-5A PF06479.12 CBY31832.1 - 2.1e-11 44.1 4.4 3.3e-11 43.5 0.5 2.5 2 1 0 2 2 2 1 Ribonuclease 2-5A LAS2 PF15792.5 CBY31832.1 - 0.074 13.6 1.1 0.47 11.0 0.1 2.6 3 0 0 3 3 3 0 Lung adenoma susceptibility protein 2 Ribosomal_L18_c PF14204.6 CBY31832.1 - 1.7 9.7 10.7 8.4 7.4 0.9 3.0 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region Peptidase_C1 PF00112.23 CBY31833.1 - 3.9e-84 282.1 1.9 5.7e-84 281.6 1.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY31833.1 - 5.4e-15 55.6 3.3 1e-14 54.7 3.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY31833.1 - 0.0011 17.9 0.3 1.1 8.0 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Meiosis_expr PF15163.6 CBY31833.1 - 0.059 14.0 5.2 0.27 11.9 0.0 3.2 3 0 0 3 3 3 0 Meiosis-expressed GDA1_CD39 PF01150.17 CBY31835.1 - 3e-68 230.4 0.0 1.4e-66 225.0 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.23 CBY31836.1 - 2.3e-72 243.6 5.3 3.6e-72 243.0 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY31836.1 - 3.1e-13 49.9 4.4 6e-13 49.0 4.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY31836.1 - 8e-06 24.9 2.1 0.0025 16.7 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBY31836.1 - 0.00011 22.0 0.3 0.00028 20.7 0.3 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.14 CBY31837.1 - 6.1e-10 39.4 0.1 6.6e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Adhesin_P1 PF03257.13 CBY31838.1 - 0.0069 16.9 0.2 0.046 14.2 0.2 2.5 1 0 0 1 1 1 1 Mycoplasma adhesin P1 PEN-2 PF10251.9 CBY31840.1 - 1.9e-05 25.0 0.3 2.8e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.14 CBY31840.1 - 0.24 11.5 3.3 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Endosulfine PF04667.17 CBY31842.1 - 7.2e-11 42.1 0.2 1.1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Myb_DNA-bind_4 PF13837.6 CBY31842.1 - 0.095 13.1 0.9 0.13 12.6 0.9 1.2 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.29 CBY31843.1 - 1.3e-44 152.1 0.0 1.9e-43 148.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY31843.1 - 1.6e-29 102.5 0.6 4.4e-29 101.0 0.5 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY31843.1 - 1.1e-07 32.0 0.0 3.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SUKH_5 PF14567.6 CBY31843.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall TRIC PF05197.13 CBY31843.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 TRIC channel CMS1 PF14617.6 CBY31843.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1829 PF08862.10 CBY31843.1 - 0.095 13.2 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF1829 AAA_22 PF13401.6 CBY31843.1 - 0.44 10.8 1.4 13 6.1 0.5 3.4 2 1 1 3 3 3 0 AAA domain Geminin PF07412.12 CBY31845.1 - 8.2e-05 22.4 15.9 0.00011 22.0 15.9 1.2 1 0 0 1 1 1 1 Geminin PA28_alpha PF02251.18 CBY31845.1 - 0.16 12.1 4.3 0.36 10.9 0.3 2.8 2 2 0 2 2 2 0 Proteasome activator pa28 alpha subunit LUC7 PF03194.15 CBY31845.1 - 0.24 11.0 12.5 0.28 10.8 12.5 1.1 1 0 0 1 1 1 0 LUC7 N_terminus UCH PF00443.29 CBY31846.1 - 4.2e-44 151.0 0.1 6.3e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CBY31846.1 - 1.7e-34 117.2 2.1 5e-11 42.3 1.1 3.6 3 0 0 3 3 3 3 UBA/TS-N domain zf-UBP_var PF17807.1 CBY31846.1 - 1.8e-18 66.0 1.6 2.4e-17 62.4 1.3 2.3 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CBY31846.1 - 2e-17 63.3 1.4 2.6e-16 59.7 0.2 2.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBY31846.1 - 2.9e-09 37.0 1.5 5.2e-07 29.6 1.5 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 CBY31846.1 - 0.041 13.7 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain Pkinase PF00069.25 CBY31847.1 - 1.6e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31847.1 - 9.7e-32 110.3 0.0 1.7e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY31847.1 - 0.0011 19.0 0.1 0.04 13.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY31847.1 - 0.011 14.7 0.0 0.038 12.9 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain COX15-CtaA PF02628.15 CBY31848.1 - 1.8e-95 319.8 3.1 2e-95 319.6 3.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 CBY31848.1 - 0.18 12.5 1.8 1.4 9.7 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PX PF00787.24 CBY31849.1 - 9e-26 90.1 0.8 4.3e-25 87.9 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CBY31849.1 - 0.00011 21.8 16.0 0.028 14.0 1.8 2.9 3 0 0 3 3 3 2 Vps5 C terminal like DUF1878 PF08963.10 CBY31849.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) Asr PF06392.11 CBY31849.1 - 0.23 11.9 1.0 0.75 10.3 1.0 1.9 1 0 0 1 1 1 0 Acid shock protein repeat RhoGEF PF00621.20 CBY31849.1 - 0.24 11.6 5.3 2.3 8.4 0.8 2.8 2 0 0 2 2 2 0 RhoGEF domain NEXCaM_BD PF16644.5 CBY31849.1 - 0.43 10.8 3.1 5.5 7.3 0.0 3.6 4 0 0 4 4 4 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin DUF3452 PF11934.8 CBY31849.1 - 1.4 8.5 5.2 0.51 9.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3452) CREPT PF16566.5 CBY31849.1 - 1.7 8.8 9.0 1.2 9.3 0.6 3.2 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour RIC3 PF15361.6 CBY31850.1 - 2.8e-07 31.0 0.5 2.8e-07 31.0 0.5 2.8 2 2 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 Syndecan PF01034.20 CBY31850.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain PIN_8 PF18476.1 CBY31850.1 - 0.16 11.8 13.6 0.11 12.4 12.1 1.4 1 1 0 1 1 1 0 PIN like domain CorA PF01544.18 CBY31850.1 - 0.22 10.8 4.0 0.84 8.9 4.0 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SieB PF14163.6 CBY31850.1 - 0.45 10.0 2.0 2.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Super-infection exclusion protein B HrpB7 PF09486.10 CBY31850.1 - 0.75 10.2 9.5 0.27 11.6 1.3 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lipoprotein_2 PF00921.17 CBY31850.1 - 2.1 7.9 20.8 0.14 11.7 9.3 2.1 2 0 0 2 2 2 0 Borrelia lipoprotein GatB_Yqey PF02637.18 CBY31850.1 - 6.7 6.6 13.3 0.072 13.0 3.0 2.1 2 0 0 2 2 2 0 GatB domain His_Phos_2 PF00328.22 CBY31851.1 - 4.2e-10 39.5 0.3 3.2e-07 30.0 0.1 3.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.9 CBY31851.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase His_Phos_2 PF00328.22 CBY31852.1 - 1.8e-10 40.7 6.2 1.9e-08 34.0 6.2 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aminotran_1_2 PF00155.21 CBY31853.1 - 6.1e-38 130.9 0.0 7.1e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CBY31853.1 - 0.056 12.0 0.1 0.36 9.3 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme PX PF00787.24 CBY31854.1 - 2.3e-13 50.1 0.1 4.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 PX domain LRR_4 PF12799.7 CBY31854.1 - 4.4e-08 33.3 17.9 1.2e-05 25.6 6.5 4.4 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY31854.1 - 1.5e-05 24.7 15.3 0.032 14.0 7.1 3.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBY31854.1 - 3e-05 23.7 1.0 0.19 11.8 0.1 4.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 CBY31854.1 - 0.00028 20.4 3.2 0.00028 20.4 3.2 2.4 2 1 1 3 3 3 2 Leucine-rich repeat SoDot-IcmSS PF16848.5 CBY31854.1 - 0.004 17.1 1.4 0.0059 16.6 0.3 1.8 2 0 0 2 2 2 1 Substrate of the Dot/Icm secretion system, putative LRR_1 PF00560.33 CBY31854.1 - 0.026 15.0 7.8 20 6.3 1.3 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat CENP-F_leu_zip PF10473.9 CBY31855.1 - 0.00046 20.2 7.6 0.0013 18.7 7.3 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 CBY31855.1 - 0.0052 17.1 4.1 0.045 14.1 1.2 2.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Filament PF00038.21 CBY31855.1 - 0.048 13.2 12.3 0.033 13.8 6.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 CBY31855.1 - 0.17 12.0 8.5 0.28 11.3 7.7 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HCV_core PF01542.18 CBY31855.1 - 0.18 12.2 0.4 33 5.0 0.2 2.5 1 1 1 2 2 2 0 Hepatitis C virus core protein ADIP PF11559.8 CBY31855.1 - 0.23 11.5 9.5 0.5 10.4 9.5 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 CBY31855.1 - 0.23 11.9 2.2 1.2 9.6 0.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CEP209_CC5 PF16574.5 CBY31855.1 - 0.23 11.6 11.2 0.31 11.2 6.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 MCC-bdg_PDZ PF10506.9 CBY31855.1 - 0.3 11.1 4.2 0.45 10.6 2.2 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 CBY31855.1 - 0.39 10.7 6.1 0.42 10.7 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 CBY31855.1 - 0.54 10.3 10.6 0.065 13.2 5.4 2.3 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding CdvA PF18822.1 CBY31855.1 - 0.54 10.1 10.8 0.89 9.4 2.2 3.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 CBY31855.1 - 0.63 9.3 10.2 0.23 10.7 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CBY31855.1 - 0.94 10.0 11.4 0.77 10.3 8.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DHR10 PF18595.1 CBY31855.1 - 1.5 8.9 9.0 3.5 7.7 8.7 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Lebercilin PF15619.6 CBY31855.1 - 1.9 8.1 14.7 0.15 11.7 8.4 2.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 CBY31855.1 - 3.1 8.3 6.2 0.53 10.7 1.3 2.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB SKA1 PF07160.12 CBY31856.1 - 6.4e-15 55.6 8.5 8.4e-15 55.3 8.5 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Ca_bind_SSO6904 PF18249.1 CBY31856.1 - 0.0013 19.0 3.4 0.0015 18.8 0.4 2.5 3 0 0 3 3 3 1 Calcium binding protein SSO6904 Spc110_C PF18520.1 CBY31856.1 - 0.19 11.3 1.8 0.27 10.9 0.2 2.1 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain Coilin_N PF15862.5 CBY31859.1 - 0.0034 17.2 3.5 0.0049 16.7 3.5 1.2 1 0 0 1 1 1 1 Coilin N-terminus NPL4 PF05021.15 CBY31860.1 - 2.3e-25 89.6 0.0 2.6e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 NPL4 family WVELL PF14043.6 CBY31860.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 WVELL protein CDC45 PF02724.14 CBY31861.1 - 2.3 6.4 7.4 2.3 6.4 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein WW PF00397.26 CBY31862.1 - 8e-07 29.0 4.1 1.2e-06 28.5 4.1 1.3 1 0 0 1 1 1 1 WW domain Gal-3-0_sulfotr PF06990.11 CBY31863.1 - 1.3e-75 254.8 0.0 2.6e-75 253.8 0.0 1.4 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase GTP-bdg_N PF13167.6 CBY31863.1 - 0.12 13.0 0.1 0.33 11.7 0.1 1.7 1 1 0 1 1 1 0 GTP-binding GTPase N-terminal SH3_1 PF00018.28 CBY31864.1 - 3.2e-16 58.7 0.4 1.5e-15 56.6 0.3 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY31864.1 - 3.2e-14 52.5 2.3 7.6e-14 51.3 0.9 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY31864.1 - 3.2e-12 45.9 0.1 5.7e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Abi_HHR PF07815.14 CBY31865.1 - 3.5e-23 81.6 0.1 7.3e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Abl-interactor HHR SH3_1 PF00018.28 CBY31865.1 - 1.6e-15 56.4 0.7 4.3e-15 55.0 0.3 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY31865.1 - 2.2e-13 49.8 2.9 2.4e-13 49.7 0.9 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY31865.1 - 8.4e-12 44.6 0.1 1.8e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Asp_protease PF09668.10 CBY31867.1 - 1e-58 196.5 0.4 1.5e-58 196.0 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY31867.1 - 3.3e-21 75.6 0.0 7.8e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBY31867.1 - 1.1e-08 35.6 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CBY31867.1 - 0.00021 21.1 0.0 0.00058 19.6 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.20 CBY31867.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 CBY31867.1 - 0.024 14.5 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain RPA_interact_M PF14767.6 CBY31867.1 - 6.9 7.3 8.2 1.8 9.2 2.7 2.9 3 1 0 3 3 3 0 Replication protein A interacting middle DUF2306 PF10067.9 CBY31868.1 - 0.13 12.5 0.1 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) PAM2 PF07145.15 CBY31869.1 - 3.2e-06 26.4 0.1 4.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Cytochrom_B561 PF03188.16 CBY31870.1 - 1.7e-27 96.3 9.6 1.7e-27 96.3 9.6 2.5 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Sdh_cyt PF01127.22 CBY31870.1 - 0.54 10.3 13.0 0.5 10.4 0.4 2.6 1 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM PF03929.16 CBY31870.1 - 3.7 7.1 9.7 83 2.7 5.2 3.2 2 1 1 3 3 3 0 PepSY-associated TM region Fis1_TPR_C PF14853.6 CBY31871.1 - 2.5e-17 62.7 2.2 4e-17 62.0 0.8 2.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CBY31871.1 - 2e-10 40.1 0.1 3.9e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CBY31871.1 - 0.014 15.4 0.2 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBY31871.1 - 0.021 15.6 0.0 1.2 10.1 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat PH PF00169.29 CBY31872.1 - 1.1e-23 83.8 0.1 1.9e-11 44.4 0.1 3.0 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.20 CBY31872.1 - 2.7e-19 70.1 0.5 6.4e-19 68.9 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain FERM_C PF09380.10 CBY31872.1 - 3.7e-15 56.1 0.5 1e-14 54.6 0.1 2.0 2 0 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY31872.1 - 3.8e-14 52.4 0.0 8.1e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain FA PF08736.11 CBY31872.1 - 1.6e-11 44.1 3.1 4.5e-11 42.6 3.1 1.8 1 0 0 1 1 1 1 FERM adjacent (FA) FERM_M PF00373.18 CBY31872.1 - 3.4e-09 37.1 0.1 1.4e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 FERM central domain PH_9 PF15410.6 CBY31872.1 - 0.13 12.7 0.7 2.3 8.6 0.3 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Sin3a_C PF16879.5 CBY31873.1 - 2.7e-37 129.1 2.2 2.7e-37 129.1 2.2 2.7 3 1 1 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 CBY31873.1 - 8.7e-35 118.6 3.3 2e-14 53.4 0.0 4.5 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CBY31873.1 - 2.1e-31 107.9 0.1 5.2e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor Clr5 PF14420.6 CBY31873.1 - 0.015 15.5 1.9 0.035 14.3 0.1 2.6 3 0 0 3 3 3 0 Clr5 domain EFTUD2 PF16004.5 CBY31873.1 - 0.023 15.2 0.1 0.5 10.9 0.0 3.2 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Herpes_Helicase PF02689.14 CBY31873.1 - 0.027 12.4 0.1 0.046 11.7 0.1 1.2 1 0 0 1 1 1 0 Helicase Endonuclease_NS PF01223.23 CBY31874.1 - 1.6e-21 77.1 2.1 2.3e-21 76.7 2.1 1.3 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Metallophos PF00149.28 CBY31875.1 - 1.7e-11 45.0 1.0 3.2e-11 44.1 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATPase_2 PF01637.18 CBY31875.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Metallophos_3 PF14582.6 CBY31875.1 - 0.026 13.9 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily LRR_8 PF13855.6 CBY31876.1 - 6.7e-76 250.0 64.5 1.8e-12 46.8 0.9 10.3 4 3 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 CBY31876.1 - 1.4e-31 108.0 72.3 3.7e-06 27.2 2.1 13.1 6 3 9 15 15 15 13 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY31876.1 - 1.6e-25 89.6 24.6 9.2e-09 35.3 2.1 6.1 4 2 2 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY31876.1 - 1.5e-13 50.6 32.7 0.0022 17.5 0.8 7.7 2 2 6 8 8 8 7 Leucine-rich repeat LRR_1 PF00560.33 CBY31876.1 - 0.21 12.2 53.5 4 8.4 0.3 14.6 13 4 1 14 14 14 0 Leucine Rich Repeat Pkinase PF00069.25 CBY31877.1 - 8.7e-71 238.4 0.0 1e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY31877.1 - 2.7e-36 125.2 0.0 3.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY31877.1 - 0.00037 19.6 0.1 0.0031 16.5 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY31877.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY31877.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CBY31877.1 - 0.027 13.8 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Exonuc_VII_L PF02601.15 CBY31878.1 - 0.0044 16.6 1.4 0.0055 16.3 1.4 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit FGAR-AT_N PF18076.1 CBY31878.1 - 0.028 14.4 0.3 0.053 13.5 0.3 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Apolipoprotein PF01442.18 CBY31878.1 - 0.061 13.2 4.7 0.13 12.1 4.7 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SKA2 PF16740.5 CBY31878.1 - 0.068 12.9 7.1 0.095 12.5 4.3 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 V_ATPase_I PF01496.19 CBY31878.1 - 0.14 10.0 2.0 0.15 10.0 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uds1 PF15456.6 CBY31878.1 - 0.47 10.6 6.2 2.2 8.5 0.1 2.4 1 1 1 2 2 2 0 Up-regulated During Septation Phasin PF05597.11 CBY31878.1 - 0.6 10.1 6.3 4.4 7.3 4.8 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TMPIT PF07851.13 CBY31878.1 - 1.4 8.1 4.4 2.1 7.5 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2408 PF10303.9 CBY31878.1 - 2.1 8.9 7.4 7.6 7.1 7.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) MerR-DNA-bind PF09278.11 CBY31878.1 - 3.6 8.2 5.3 1.8 9.1 0.1 2.5 2 1 0 2 2 2 0 MerR, DNA binding ING PF12998.7 CBY31878.1 - 6.7 7.4 9.2 8.7 7.0 8.0 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ank_2 PF12796.7 CBY31879.1 - 0.04 14.5 0.0 0.71 10.5 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY31879.1 - 0.14 12.7 0.0 9.7 7.1 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat EGF_3 PF12947.7 CBY31880.1 - 0.00056 20.1 6.2 0.0011 19.1 6.2 1.4 1 0 0 1 1 1 1 EGF domain Orf78 PF06024.12 CBY31880.1 - 0.0097 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Get5_C PF18514.1 CBY31880.1 - 0.014 15.1 0.1 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 Get5 C-terminal domain DUF4051 PF13260.6 CBY31880.1 - 0.039 13.7 2.1 0.041 13.6 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) EGF PF00008.27 CBY31880.1 - 0.44 10.9 4.0 0.76 10.1 4.0 1.4 1 0 0 1 1 1 0 EGF-like domain cEGF PF12662.7 CBY31880.1 - 0.47 10.4 2.8 0.32 11.0 0.7 1.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY31880.1 - 1 9.7 4.6 2.1 8.7 4.6 1.5 1 0 0 1 1 1 0 Pvs28 EGF domain EGF_CA PF07645.15 CBY31880.1 - 2.4 8.4 7.3 4.3 7.6 7.3 1.4 1 0 0 1 1 1 0 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY31880.1 - 5 7.5 7.4 8.6 6.7 7.4 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site VWA PF00092.28 CBY31881.1 - 5.9e-34 117.8 1.4 8.5e-34 117.3 0.3 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain fn3 PF00041.21 CBY31881.1 - 1.4e-22 79.8 10.7 1.8e-05 25.0 0.1 8.7 8 1 2 10 10 10 5 Fibronectin type III domain VWA_2 PF13519.6 CBY31881.1 - 2.1e-10 41.2 0.0 5.4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain MOSC_N PF03476.16 CBY31881.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain Glyco_hydro_9 PF00759.19 CBY31882.1 - 2.3e-121 406.1 2.6 2.7e-121 405.9 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SSF PF00474.17 CBY31883.1 - 1.3e-101 340.5 22.9 2.6e-100 336.2 22.9 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family Pro_isomerase PF00160.21 CBY31886.1 - 6.8e-27 94.7 0.1 7.5e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 CBY31887.1 - 8.5e-08 32.2 41.0 0.0072 16.7 0.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY31887.1 - 2.3e-07 30.9 33.8 0.00063 20.1 0.4 5.5 6 0 0 6 6 6 4 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY31887.1 - 0.0001 22.0 4.2 0.0001 22.0 4.2 4.8 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY31887.1 - 0.00017 22.1 40.0 0.16 12.9 2.3 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY31887.1 - 0.061 13.6 10.1 0.2 12.0 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY31887.1 - 0.095 13.1 0.0 0.095 13.1 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GAGA PF09237.11 CBY31887.1 - 0.49 10.2 4.0 12 5.8 0.1 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_8 PF15909.5 CBY31887.1 - 0.69 10.2 14.7 0.92 9.9 1.0 3.2 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-3CxxC_2 PF17180.4 CBY31888.1 - 7.8e-25 87.4 13.1 7.8e-25 87.4 13.1 1.7 2 0 0 2 2 2 1 Zinc-binding domain zf-CCHC_2 PF13696.6 CBY31888.1 - 4.7e-10 39.1 2.0 1.8e-09 37.2 2.0 2.1 1 0 0 1 1 1 1 Zinc knuckle UPF0515 PF15135.6 CBY31888.1 - 0.00025 20.5 7.9 0.00031 20.2 7.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 zf-3CxxC PF13695.6 CBY31888.1 - 0.003 18.0 18.1 0.063 13.8 17.3 2.9 2 1 0 2 2 2 1 Zinc-binding domain zf-CCHC PF00098.23 CBY31888.1 - 0.047 13.8 0.6 0.047 13.8 0.6 3.2 3 0 0 3 3 3 0 Zinc knuckle PPP1R35_C PF15503.6 CBY31889.1 - 6.1e-35 120.2 0.7 1e-34 119.4 0.7 1.4 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus BcrAD_BadFG PF01869.20 CBY31890.1 - 1.8e-21 76.8 0.1 2.1e-21 76.6 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family TAL_effector PF03377.13 CBY31890.1 - 0.0074 16.6 0.5 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 TAL effector repeat ROK PF00480.20 CBY31890.1 - 0.056 12.9 0.0 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 ROK family ORMDL PF04061.14 CBY31891.1 - 1.1e-49 167.7 5.6 1.3e-49 167.5 5.6 1.0 1 0 0 1 1 1 1 ORMDL family CitMHS PF03600.16 CBY31891.1 - 0.17 11.0 1.1 0.21 10.7 1.1 1.1 1 0 0 1 1 1 0 Citrate transporter TMEM208_SND2 PF05620.11 CBY31891.1 - 0.56 10.0 4.7 0.28 10.9 0.5 2.0 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 ArsA_ATPase PF02374.15 CBY31892.1 - 1.2e-102 343.2 0.0 1.5e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CBY31892.1 - 5.1e-11 42.8 0.2 2.1e-10 40.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CBY31892.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CBY31892.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CBY31892.1 - 0.00064 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CBY31892.1 - 0.00069 19.1 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CBY31892.1 - 0.0021 17.7 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBY31892.1 - 0.085 12.1 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sucrose_synth PF00862.19 CBY31893.1 - 0.00037 19.0 0.4 0.00066 18.1 0.4 1.3 1 0 0 1 1 1 1 Sucrose synthase CAP_N PF01213.19 CBY31893.1 - 2.2 7.7 10.6 0.23 10.9 4.8 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Enolase_N PF03952.16 CBY31894.1 - 6.4e-55 184.9 0.6 1.4e-54 183.8 0.6 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 CBY31894.1 - 1.5e-45 155.7 0.1 2.5e-45 155.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain PPC PF04151.15 CBY31894.1 - 0.052 14.6 0.0 0.14 13.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain Alpha-amylase_C PF02806.18 CBY31895.1 - 1e-21 77.2 0.0 2.9e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CBY31895.1 - 6.8e-13 48.9 0.1 3.1e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 CBY31895.1 - 4.6e-08 33.3 0.1 1.3e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.18 CBY31895.1 - 0.047 13.1 0.3 2.7 7.3 0.0 2.3 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Tubulin PF00091.25 CBY31896.1 - 8e-68 228.5 0.0 1.5e-67 227.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY31896.1 - 3.8e-50 169.3 0.1 6e-50 168.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY31896.1 - 0.00066 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CBY31896.1 - 0.022 15.1 0.1 0.052 13.9 0.1 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Sugar_tr PF00083.24 CBY31897.1 - 1.2e-35 123.3 16.6 3.3e-35 121.8 16.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY31897.1 - 4.2e-13 48.9 43.3 6.3e-09 35.2 18.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin PF00089.26 CBY31898.1 - 9.3e-55 185.8 0.0 1.5e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY31898.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) TPR_14 PF13428.6 CBY31900.1 - 3e-18 65.0 4.8 0.083 13.7 0.1 12.2 8 3 5 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY31900.1 - 1e-12 47.9 10.0 0.00061 19.1 0.2 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat Suf PF05843.14 CBY31900.1 - 9.5e-09 35.7 28.8 0.0021 18.1 0.3 6.7 4 1 0 6 6 6 3 Suppressor of forked protein (Suf) TPR_12 PF13424.6 CBY31900.1 - 3.8e-07 30.3 9.5 0.00024 21.3 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY31900.1 - 6.5e-07 29.1 11.5 1.1 9.6 0.1 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY31900.1 - 4.7e-06 27.0 6.3 14 6.2 0.0 8.0 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31900.1 - 4.9e-06 26.2 18.8 0.89 9.8 0.2 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY31900.1 - 0.00013 22.0 19.0 0.088 12.8 0.8 6.7 5 2 2 7 7 7 2 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 CBY31900.1 - 0.0017 18.6 4.2 84 3.9 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CBY31900.1 - 0.002 17.4 20.3 0.25 10.4 0.1 6.0 3 3 2 5 5 5 3 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 CBY31900.1 - 0.0023 18.0 0.7 7.6 6.8 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat AEP1 PF17049.5 CBY31900.1 - 0.0031 16.7 0.2 1.7 7.6 0.1 2.3 2 0 0 2 2 2 2 ATPase expression protein 1 TPR_16 PF13432.6 CBY31900.1 - 0.0079 16.8 3.1 1.1 10.0 0.1 4.9 8 0 0 8 8 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY31900.1 - 0.046 13.8 1.2 4.9 7.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 CBY31900.1 - 0.053 12.9 9.8 0.053 13.0 0.6 4.5 5 1 3 8 8 8 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CBY31900.1 - 0.062 14.0 12.2 67 4.4 0.0 7.4 10 0 0 10 10 6 0 Tetratricopeptide repeat DALR_1 PF05746.15 CBY31900.1 - 0.11 12.7 1.4 0.92 9.7 0.1 3.0 2 0 0 2 2 2 0 DALR anticodon binding domain Ferlin_C PF16165.5 CBY31901.1 - 2.2e-29 102.4 0.7 5.6e-23 81.6 0.0 2.4 1 1 1 2 2 2 2 Ferlin C-terminus C2 PF00168.30 CBY31901.1 - 1.1e-28 99.5 0.0 1.1e-17 64.2 0.0 4.4 3 1 0 3 3 3 3 C2 domain DUF2154 PF09922.9 CBY31901.1 - 0.068 13.1 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF FerB PF08150.12 CBY31902.1 - 8e-30 103.3 0.0 1.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 FerB (NUC096) domain C2 PF00168.30 CBY31902.1 - 1.1e-09 38.4 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Mrr_cat_2 PF13156.6 CBY31903.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease C2 PF00168.30 CBY31904.1 - 8.2e-23 80.7 0.3 2.6e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain FerI PF08151.12 CBY31904.1 - 4.2e-14 52.4 0.1 4.2e-14 52.4 0.1 2.6 3 0 0 3 3 3 1 FerI (NUC094) domain DEAD PF00270.29 CBY31906.1 - 4.2e-49 166.7 0.0 8.1e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY31906.1 - 8.3e-27 93.7 0.6 6.7e-26 90.8 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY31906.1 - 4.6e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY31906.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Tra_M PF05261.11 CBY31906.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TraM protein, DNA-binding HABP4_PAI-RBP1 PF04774.15 CBY31906.1 - 2.7 8.9 7.2 6.2 7.7 6.5 1.8 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family zf-UBR PF02207.20 CBY31907.1 - 8.9e-18 64.2 11.2 8.9e-18 64.2 11.2 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CBY31907.1 - 2.4e-13 49.7 0.1 9e-13 47.8 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 CBY31907.1 - 0.0027 17.7 0.3 0.0027 17.7 0.3 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY31907.1 - 0.021 14.6 0.3 0.021 14.6 0.3 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.23 CBY31907.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SPACA7 PF15307.6 CBY31907.1 - 9.7 6.5 6.7 1.8 8.9 0.3 2.9 3 0 0 3 3 3 0 Sperm acrosome-associated protein 7 TMIE PF16038.5 CBY31908.1 - 0.05 13.5 0.6 0.05 13.5 0.6 2.5 2 1 1 3 3 3 0 TMIE protein Med19 PF10278.9 CBY31908.1 - 2 8.3 13.7 0.64 9.9 7.2 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SAM_KSR1 PF13543.6 CBY31909.1 - 0.75 9.9 4.5 1.6 8.9 4.5 1.5 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Atg14 PF10186.9 CBY31909.1 - 5.9 5.9 12.2 12 4.9 12.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CBY31909.1 - 7.6 6.6 7.2 1.6 8.7 2.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RVT_1 PF00078.27 CBY31910.1 - 3.1e-28 98.8 0.0 9.2e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_9 PF17674.1 CBY31910.1 - 0.024 15.5 0.9 22 6.0 0.1 4.0 2 0 0 2 2 2 0 HHH domain Involucrin_N PF10583.9 CBY31910.1 - 0.39 11.3 3.5 0.16 12.5 0.4 2.0 2 0 0 2 2 2 0 Involucrin of squamous epithelia N-terminus Ribosomal_L30_N PF08079.12 CBY31913.1 - 0.0068 16.6 1.0 1.7 8.9 0.9 2.8 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain AJAP1_PANP_C PF15298.6 CBY31913.1 - 0.64 10.2 13.9 1.4 9.1 13.9 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Dicty_REP PF05086.12 CBY31913.1 - 3.7 5.4 7.2 4.7 5.1 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gal-3-0_sulfotr PF06990.11 CBY31914.1 - 4.3e-28 98.3 0.7 5.3e-27 94.7 0.7 1.9 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY31914.1 - 1.5e-06 28.4 0.3 3.1e-06 27.3 0.3 1.5 1 1 0 1 1 1 1 Sulfotransferase family EF-hand_1 PF00036.32 CBY31915.1 - 2e-11 42.6 0.6 6.9e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY31915.1 - 5.4e-11 41.5 1.4 4.4e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY31915.1 - 3.3e-06 27.5 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY31915.1 - 6.7e-05 22.2 0.9 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY31915.1 - 0.014 15.2 0.8 2.9 7.8 0.1 3.3 2 2 1 3 3 3 0 EF-hand domain pair TRP PF06011.12 CBY31916.1 - 0.014 14.2 1.0 0.015 14.1 1.0 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF5643 PF18705.1 CBY31916.1 - 0.035 14.1 0.9 0.052 13.5 0.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5643) Orf78 PF06024.12 CBY31916.1 - 0.062 13.6 0.5 0.093 13.0 0.5 1.4 1 1 0 1 1 1 0 Orf78 (ac78) SARAF PF06682.12 CBY31916.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Lysyl_oxidase PF01186.17 CBY31917.1 - 1.3e-89 299.3 2.7 1.3e-89 299.3 2.7 1.9 2 0 0 2 2 2 1 Lysyl oxidase SRCR PF00530.18 CBY31917.1 - 5e-80 264.4 31.0 1.2e-23 83.5 1.9 5.7 5 1 1 6 6 6 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY31917.1 - 2.7e-28 98.4 16.6 3.1e-10 40.4 0.4 5.1 4 2 0 4 4 4 4 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY31917.1 - 8.9e-11 42.3 3.8 0.22 12.0 0.0 4.8 4 1 0 4 4 4 4 Hepsin, SRCR domain DUF2196 PF09962.9 CBY31917.1 - 0.08 12.9 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) TauD PF02668.16 CBY31918.1 - 3.4e-30 105.8 0.0 4.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CBY31918.1 - 1.6e-05 24.2 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 CsiD UnbV_ASPIC PF07593.12 CBY31918.1 - 0.079 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV MBD PF01429.19 CBY31922.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain zf-NPL4 PF05020.15 CBY31922.1 - 0.065 13.4 0.7 0.082 13.1 0.7 1.2 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region PI_PP_I PF18363.1 CBY31922.1 - 0.082 13.1 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain TPR_1 PF00515.28 CBY31923.1 - 8.1e-30 101.4 16.2 9e-08 31.6 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31923.1 - 1.1e-28 96.9 14.4 6.2e-06 25.9 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 CBY31923.1 - 8.7e-23 78.6 10.5 0.0016 18.5 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBY31923.1 - 3.5e-19 68.2 3.9 5.6e-07 29.1 0.0 6.5 4 2 4 8 8 7 4 TPR repeat TPR_14 PF13428.6 CBY31923.1 - 1.5e-18 65.9 4.1 0.041 14.7 0.0 9.6 7 1 3 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY31923.1 - 2.9e-17 62.7 18.4 5e-09 36.3 0.1 4.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY31923.1 - 4.5e-17 62.3 1.3 9.4e-05 22.8 0.4 5.7 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY31923.1 - 2.7e-16 59.9 0.8 7e-05 23.4 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY31923.1 - 4.9e-16 57.9 10.4 7.2e-05 22.9 0.5 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY31923.1 - 5e-11 41.8 0.7 0.91 9.7 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY31923.1 - 5.2e-11 42.7 15.9 4.2e-05 23.7 0.0 7.3 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBY31923.1 - 4.9e-07 29.8 0.0 0.0013 18.8 0.0 4.2 4 1 2 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.8 CBY31923.1 - 1e-06 28.0 0.7 0.00077 18.5 0.3 2.9 1 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 CBY31923.1 - 5.3e-06 25.9 3.2 6.2e-05 22.3 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY31923.1 - 1.8e-05 25.1 5.0 11 6.9 0.0 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF3808 PF10300.9 CBY31923.1 - 0.00039 19.3 0.4 0.0011 17.7 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) HrpB1_HrpK PF09613.10 CBY31923.1 - 0.0012 18.4 0.0 0.027 14.1 0.0 2.5 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 CBY31923.1 - 0.0013 18.2 1.9 0.51 9.7 0.1 3.6 2 1 2 4 4 4 1 MalT-like TPR region DUF4919 PF16266.5 CBY31923.1 - 0.0017 18.3 0.9 0.26 11.2 0.1 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4919) TPR_10 PF13374.6 CBY31923.1 - 0.0098 15.7 1.1 73 3.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.12 CBY31923.1 - 0.01 15.8 0.7 0.72 9.9 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF627) ChAPs PF09295.10 CBY31923.1 - 0.017 14.1 0.1 0.83 8.6 0.0 2.7 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4248 PF14053.6 CBY31923.1 - 0.032 14.3 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) TPR_20 PF14561.6 CBY31923.1 - 0.058 13.7 1.8 0.61 10.5 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CBY31923.1 - 0.87 9.6 3.8 1.2 9.1 0.7 2.8 3 1 1 4 4 3 0 Putative TPR-like repeat RCC1 PF00415.18 CBY31924.1 - 8.3e-24 84.0 6.6 0.0037 17.9 0.0 8.8 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY31924.1 - 0.022 14.6 27.7 0.27 11.1 0.4 7.9 8 1 0 8 8 8 0 Regulator of chromosome condensation (RCC1) repeat Motile_Sperm PF00635.26 CBY31925.1 - 4e-26 91.0 1.4 9.4e-26 89.8 0.6 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain FlxA PF14282.6 CBY31925.1 - 0.0046 16.9 0.6 0.0046 16.9 0.6 2.2 2 0 0 2 2 2 1 FlxA-like protein PEP-utilisers_N PF05524.13 CBY31925.1 - 0.024 14.8 1.1 0.034 14.3 0.5 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TIG_plexin PF17960.1 CBY31925.1 - 0.027 14.5 0.1 0.1 12.6 0.1 1.9 1 1 0 1 1 1 0 TIG domain Neur_chan_memb PF02932.16 CBY31925.1 - 0.051 13.6 1.3 0.065 13.3 1.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LapA_dom PF06305.11 CBY31925.1 - 0.64 9.9 2.1 1.7 8.5 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NARP1 PF12569.8 CBY31925.1 - 0.97 8.3 11.1 1.2 7.9 11.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cupin_8 PF13621.6 CBY31926.1 - 6.8e-18 65.3 0.0 8.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain His_Phos_2 PF00328.22 CBY31927.1 - 2.2e-14 53.6 0.1 4.9e-14 52.5 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) AMP-binding PF00501.28 CBY31928.1 - 2.6e-93 312.9 0.0 3.5e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Phospholip_A2_1 PF00068.19 CBY31929.1 - 1.2e-17 64.4 8.9 1.2e-17 64.4 8.9 1.6 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY31930.1 - 0.046 14.2 0.3 0.13 12.7 0.2 1.7 2 0 0 2 2 2 0 Phospholipase A2 DUF1186 PF06685.11 CBY31930.1 - 0.17 11.2 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) zf-H2C2_2 PF13465.6 CBY31932.1 - 9.4e-18 63.8 10.8 2.1e-07 31.0 0.5 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY31932.1 - 7.7e-12 45.0 12.7 0.0017 18.7 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY31932.1 - 5.3e-10 39.3 12.4 0.0026 18.4 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY31932.1 - 4.4e-07 30.0 0.3 0.017 15.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY31932.1 - 0.00015 22.0 3.6 4.4 7.8 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY31932.1 - 0.0025 18.0 2.8 0.19 12.0 0.1 3.1 2 1 1 3 3 3 1 TFIIH C1-like domain zf-C2HE PF16278.5 CBY31932.1 - 0.0087 16.5 2.8 6.2 7.4 2.9 3.3 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 CBY31932.1 - 0.012 15.8 6.2 10 6.4 0.2 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger PyrI_C PF02748.15 CBY31932.1 - 0.02 14.8 0.7 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.14 CBY31932.1 - 0.035 14.1 1.5 0.056 13.4 0.2 2.2 2 0 0 2 2 1 0 Adenylate kinase, active site lid LIM PF00412.22 CBY31932.1 - 0.043 14.1 4.6 0.2 11.9 2.8 2.4 2 1 0 2 2 2 0 LIM domain zf_UBZ PF18439.1 CBY31932.1 - 0.075 12.6 1.4 2.6 7.7 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CBY31932.1 - 0.076 12.8 0.3 0.076 12.8 0.3 2.3 3 0 0 3 3 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY31932.1 - 0.14 12.2 9.9 0.56 10.3 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.13 CBY31932.1 - 1.2 9.2 3.7 2.2 8.4 0.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-LYAR PF08790.11 CBY31932.1 - 1.4 8.9 3.4 6.1 6.8 0.1 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CHCC PF10276.9 CBY31932.1 - 1.6 8.9 8.3 1.1 9.3 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-FCS PF06467.14 CBY31932.1 - 1.7 8.6 6.9 12 6.0 0.9 3.0 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.7 CBY31932.1 - 1.9 8.9 4.9 62 4.0 5.1 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 CBY31932.1 - 2.7 8.7 5.2 1.6 9.5 2.0 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 CBY31932.1 - 3.3 7.9 10.1 9.4 6.4 1.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain RAP1 PF07218.11 CBY31932.1 - 5 5.3 6.1 8.4 4.5 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-BED PF02892.15 CBY31932.1 - 5.1 7.2 8.9 6.3 6.9 0.6 3.2 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_3rep PF18868.1 CBY31932.1 - 8.8 7.0 9.0 6.5 7.4 0.1 3.6 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats FYDLN_acid PF09538.10 CBY31932.1 - 9 7.0 11.5 0.67 10.7 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF664 PF04978.12 CBY31933.1 - 0.068 13.6 0.8 0.29 11.5 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF664) DUF2852 PF11014.8 CBY31933.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) LMP PF04778.12 CBY31933.1 - 0.17 11.8 1.7 0.9 9.4 0.4 2.0 2 0 0 2 2 2 0 LMP repeated region TPR_1 PF00515.28 CBY31933.1 - 1.3 9.0 4.0 0.54 10.2 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY31933.1 - 4.8 7.5 7.7 1 9.6 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Alanine_zipper PF11839.8 CBY31933.1 - 6.3 7.2 13.3 11 6.5 7.3 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein YHYH PF14240.6 CBY31934.1 - 7.5e-16 58.7 2.3 3.1e-14 53.4 2.3 2.4 1 1 0 1 1 1 1 YHYH protein Glyco_hydro_18 PF00704.28 CBY31935.1 - 1.5e-75 254.8 5.2 2e-75 254.4 5.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY31935.1 - 4.9e-10 39.4 11.7 4.9e-10 39.4 11.7 2.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain SAND PF01342.21 CBY31936.1 - 1.1e-21 76.4 1.0 2.2e-21 75.3 1.0 1.5 1 0 0 1 1 1 1 SAND domain Kelch_6 PF13964.6 CBY31937.1 - 0.01 16.1 4.0 34 4.9 0.1 4.6 4 1 1 5 5 5 0 Kelch motif Somatomedin_B PF01033.17 CBY31938.1 - 0.0012 19.2 22.3 0.0012 19.2 22.3 2.5 2 1 0 2 2 2 1 Somatomedin B domain DUF726 PF05277.12 CBY31938.1 - 0.34 9.8 1.3 0.47 9.3 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RNA_pol_Rpb2_6 PF00562.28 CBY31939.1 - 4.9e-116 388.0 4.3 2.8e-74 250.6 0.8 2.8 2 1 1 3 3 3 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBY31939.1 - 2.3e-48 164.4 1.1 4.4e-48 163.5 1.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CBY31939.1 - 6.6e-32 109.8 0.1 2.2e-31 108.1 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CBY31939.1 - 3e-22 78.7 0.1 7.6e-22 77.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBY31939.1 - 8.5e-18 64.3 0.0 2.1e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CBY31939.1 - 9.5e-14 51.5 4.6 3.9e-13 49.5 4.6 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 CBY31939.1 - 1e-11 45.2 0.1 3.8e-11 43.4 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 bacHORMA_2 PF18173.1 CBY31939.1 - 0.039 13.8 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial HORMA domain 2 Nop14 PF04147.12 CBY31940.1 - 0.099 10.8 35.3 0.11 10.6 35.3 1.0 1 0 0 1 1 1 0 Nop14-like family SR-25 PF10500.9 CBY31940.1 - 0.78 9.3 81.8 1.3 8.6 79.5 2.2 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PWI PF01480.17 CBY31941.1 - 4.6e-20 71.7 0.0 7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain RSRP PF17069.5 CBY31941.1 - 0.071 12.7 17.5 0.098 12.2 17.5 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Transformer PF06495.11 CBY31941.1 - 0.18 11.9 14.7 0.47 10.5 14.7 1.6 2 0 0 2 2 2 0 Fruit fly transformer protein Secretin_N_2 PF07655.13 CBY31941.1 - 0.26 11.8 5.5 0.53 10.9 5.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain zf-C3HC4_2 PF13923.6 CBY31942.1 - 0.0014 18.4 13.0 0.0014 18.4 13.0 2.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF4659 PF15558.6 CBY31943.1 - 3e-09 36.3 110.0 3e-09 36.3 110.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4659) Phospholip_A2_1 PF00068.19 CBY31944.1 - 3.1e-11 43.7 10.1 3.1e-11 43.7 10.1 2.3 2 0 0 2 2 2 1 Phospholipase A2 Metallopep PF12044.8 CBY31944.1 - 0.11 11.1 0.6 0.23 10.0 0.5 1.5 2 0 0 2 2 2 0 Putative peptidase family Nramp PF01566.18 CBY31945.1 - 6.1e-114 380.7 9.5 6.1e-114 380.7 9.5 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein ATP-synt_F PF01990.17 CBY31946.1 - 5.4e-29 100.4 0.1 6.2e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Peptidase_M16 PF00675.20 CBY31947.1 - 2.9e-35 121.4 0.0 5.2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY31947.1 - 4.3e-23 82.3 0.0 1.6e-21 77.2 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain zf-CCCH PF00642.24 CBY31948.1 - 1.4e-17 63.2 11.9 4.2e-10 39.3 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY31948.1 - 7.5e-08 32.0 9.9 4.5e-05 23.1 2.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY31948.1 - 2.1e-07 30.8 13.4 3e-05 23.9 4.0 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CBY31948.1 - 0.031 15.0 8.1 0.15 12.8 0.9 2.3 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 CBY31948.1 - 0.63 10.6 3.1 21 5.7 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_2 PF14608.6 CBY31948.1 - 0.69 10.5 10.9 4 8.1 1.0 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger LRR_5 PF13306.6 CBY31949.1 - 4e-08 33.3 0.2 4e-08 33.3 0.2 2.4 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CBY31949.1 - 2.2e-05 24.1 0.1 0.0016 18.2 0.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.18 CBY31949.1 - 0.024 14.3 2.4 0.024 14.3 2.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-RING_2 PF13639.6 CBY31950.1 - 1.6e-05 25.1 3.8 1.6e-05 25.1 3.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY31950.1 - 0.0003 20.8 2.9 0.00079 19.4 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY31950.1 - 0.0072 16.3 6.8 0.0072 16.3 6.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY31950.1 - 0.019 14.8 5.0 0.019 14.8 5.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY31950.1 - 0.39 10.5 4.8 0.89 9.4 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY31950.1 - 0.55 10.1 9.7 0.065 13.1 4.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY31950.1 - 2.9 8.1 6.8 0.65 10.2 2.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING LRR_5 PF13306.6 CBY31951.1 - 3.2e-08 33.6 0.2 3.2e-08 33.6 0.2 2.4 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CBY31951.1 - 1.8e-05 24.4 0.1 0.0013 18.4 0.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.18 CBY31951.1 - 0.024 14.3 2.4 0.024 14.3 2.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain adh_short PF00106.25 CBY31952.1 - 1.6e-44 151.7 2.1 2e-44 151.4 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY31952.1 - 1.3e-26 93.6 0.4 1.7e-26 93.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY31952.1 - 2.1e-11 44.1 0.5 3.3e-11 43.4 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY31952.1 - 0.0003 20.4 1.4 0.0014 18.2 1.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBY31952.1 - 0.00068 18.9 0.5 0.0011 18.2 0.5 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CBY31952.1 - 0.00086 18.8 0.6 0.052 13.0 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CBY31952.1 - 0.0031 17.2 0.5 0.0079 15.9 0.4 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CBY31952.1 - 0.0039 17.1 0.4 0.0068 16.3 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CBY31952.1 - 0.035 14.0 1.4 0.056 13.3 0.8 1.5 1 1 0 1 1 1 0 NAD(P)H-binding OrfB_Zn_ribbon PF07282.11 CBY31952.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pyr_redox PF00070.27 CBY31952.1 - 0.11 13.0 0.8 0.39 11.3 0.5 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CBY31952.1 - 0.15 12.3 0.9 0.56 10.5 0.8 1.9 1 1 0 1 1 1 0 TrkA-N domain SLX9 PF15341.6 CBY31953.1 - 1.6e-06 28.5 9.0 1.6e-06 28.5 9.0 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Lon_2 PF13337.6 CBY31953.1 - 0.034 12.7 0.2 0.054 12.0 0.2 1.3 1 1 0 1 1 1 0 Putative ATP-dependent Lon protease SRI PF08236.11 CBY31953.1 - 3.2 8.0 12.3 1 9.6 0.6 2.7 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain HMG_box_2 PF09011.10 CBY31953.1 - 8.7 7.0 7.7 12 6.5 0.7 2.5 2 0 0 2 2 2 0 HMG-box domain Clat_adaptor_s PF01217.20 CBY31954.1 - 6e-52 175.3 2.1 7.9e-52 175.0 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LNS2 PF08235.13 CBY31955.1 - 2.8e-89 298.5 0.3 3.8e-89 298.1 0.3 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CBY31955.1 - 6.3e-20 71.0 0.0 2.2e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 CBY31955.1 - 2.6e-16 59.6 0.5 1.7e-15 57.0 0.0 2.5 2 1 1 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain PHO4 PF01384.20 CBY31957.1 - 1.1e-116 389.6 15.4 1.7e-116 389.0 15.4 1.3 1 0 0 1 1 1 1 Phosphate transporter family DUF4612 PF15389.6 CBY31958.1 - 0.2 12.7 3.0 0.29 12.2 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Cortexin PF11057.8 CBY31959.1 - 0.00023 20.9 0.8 0.97 9.3 0.1 3.4 3 0 0 3 3 3 1 Cortexin of kidney Saf_2TM PF18303.1 CBY31959.1 - 0.0049 16.5 2.6 0.68 9.5 1.1 2.2 2 0 0 2 2 2 2 SAVED-fused 2TM effector domain DUF2157 PF09925.9 CBY31959.1 - 0.0072 16.1 4.3 4.4 7.1 0.0 2.6 2 1 0 2 2 2 2 Predicted membrane protein (DUF2157) Frag1 PF10277.9 CBY31959.1 - 0.011 15.2 10.9 0.011 15.2 10.9 1.8 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family SdpI PF13630.6 CBY31959.1 - 0.067 13.3 3.9 0.79 9.9 0.7 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family PMP22_Claudin PF00822.20 CBY31959.1 - 0.077 12.9 7.1 0.098 12.5 0.3 2.8 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF3899 PF13038.6 CBY31959.1 - 0.12 12.9 4.5 1.6 9.3 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Pox_A14 PF05767.12 CBY31959.1 - 0.25 11.5 0.2 0.25 11.5 0.2 3.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Na_Ala_symp PF01235.17 CBY31959.1 - 0.4 9.9 7.4 0.13 11.5 4.4 1.7 2 1 0 2 2 2 0 Sodium:alanine symporter family SpoIIM PF01944.17 CBY31959.1 - 0.47 10.5 9.8 2.4 8.2 9.8 2.0 1 1 0 1 1 1 0 Stage II sporulation protein M DUF5383 PF17355.2 CBY31959.1 - 0.79 10.1 2.3 1.9 8.9 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Zip PF02535.22 CBY31960.1 - 1.9e-44 152.3 8.9 1.9e-37 129.2 0.2 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF456 PF04306.13 CBY31960.1 - 0.019 15.3 0.9 0.019 15.3 0.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF456) SirB PF04247.12 CBY31960.1 - 0.065 13.3 4.9 0.21 11.7 0.5 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB TMEM65 PF10507.9 CBY31960.1 - 0.095 12.7 6.5 1.5 8.8 0.1 3.8 3 2 1 4 4 4 0 Transmembrane protein 65 P2 PF07194.11 CBY31960.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain HXXEE PF13787.6 CBY31960.1 - 0.37 11.6 5.2 3.4 8.5 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function with HXXEE motif Peptidase_M19 PF01244.21 CBY31961.1 - 3.8e-90 302.3 0.0 4.7e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PIP49_C PF12260.8 CBY31963.1 - 0.082 12.5 0.0 0.082 12.5 0.0 2.1 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 Eaf7 PF07904.13 CBY31963.1 - 0.13 12.6 1.2 0.4 11.1 0.5 2.0 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 AMP-binding PF00501.28 CBY31964.1 - 1.4e-70 238.1 0.0 1.8e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY31964.1 - 0.0072 17.3 0.0 0.016 16.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 CBY31964.1 - 0.13 12.2 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Cyclophilin-like family Tctex-1 PF03645.13 CBY31965.1 - 2.5e-22 79.0 2.0 2.9e-22 78.8 2.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF2004 PF09406.10 CBY31965.1 - 0.032 14.5 0.1 0.041 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) DNA_pol_A_exo1 PF01612.20 CBY31966.1 - 4.6e-14 52.5 0.0 7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Stc1 PF12898.7 CBY31966.1 - 0.021 15.4 0.5 0.059 13.9 0.5 1.8 1 0 0 1 1 1 0 Stc1 domain Kinesin PF00225.23 CBY31967.1 - 4.7e-97 324.9 0.4 4.7e-97 324.9 0.4 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY31967.1 - 1.3e-29 103.0 2.4 1.5e-29 102.8 0.2 2.2 2 0 0 2 2 2 1 Microtubule binding CENP-F_leu_zip PF10473.9 CBY31967.1 - 0.016 15.2 2.6 0.016 15.2 2.6 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PIF1 PF05970.14 CBY31967.1 - 0.035 13.3 0.3 0.093 11.9 0.3 1.6 1 0 0 1 1 1 0 PIF1-like helicase Homoserine_dh PF00742.19 CBY31967.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase AAA_16 PF13191.6 CBY31967.1 - 0.3 11.5 2.9 18 5.7 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Mvb12 PF09452.10 CBY31967.1 - 1.4 9.4 6.0 2.1 8.8 0.4 3.4 3 1 1 4 4 4 0 ESCRT-I subunit Mvb12 Exo84_C PF16528.5 CBY31967.1 - 1.8 8.3 8.8 0.37 10.6 2.8 2.7 2 0 0 2 2 2 0 Exocyst component 84 C-terminal COG5 PF10392.9 CBY31967.1 - 1.8 8.8 14.9 1.4 9.1 1.6 3.5 3 1 0 3 3 3 0 Golgi transport complex subunit 5 OTU PF02338.19 CBY31968.1 - 7e-18 65.3 0.3 4.7e-17 62.7 0.0 2.3 2 1 1 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBY31968.1 - 2.2e-06 27.3 0.9 0.054 12.9 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain Chromo PF00385.24 CBY31968.1 - 0.00029 20.7 0.1 0.00077 19.3 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5347 PF17282.2 CBY31968.1 - 0.026 14.8 0.7 0.31 11.4 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5347) Phage_GPA PF05840.13 CBY31968.1 - 0.03 13.4 0.8 0.049 12.7 0.1 1.7 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) UCR_14kD PF02271.16 CBY31968.1 - 0.031 14.2 0.1 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit PWWP PF00855.17 CBY31968.1 - 0.048 14.1 0.5 0.048 14.1 0.5 1.9 2 0 0 2 2 2 0 PWWP domain Ank_2 PF12796.7 CBY31969.1 - 4.2e-10 40.1 0.1 6.4e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY31969.1 - 5.5e-09 36.4 0.1 0.0015 19.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY31969.1 - 4.9e-07 29.9 0.2 0.00082 19.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY31969.1 - 7.5e-05 22.8 0.1 4.7 8.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY31969.1 - 9.3e-05 22.7 0.6 0.076 13.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat BLACT_WH PF17778.1 CBY31969.1 - 0.017 15.1 0.8 1.9 8.5 0.2 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain Glyco_transf_10 PF00852.19 CBY31970.1 - 6.1e-20 71.7 1.1 6.6e-18 65.0 1.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY31970.1 - 3.1e-18 66.3 0.5 2.1e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal TSP_1 PF00090.19 CBY31971.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Thrombospondin type 1 domain DUF3149 PF11346.8 CBY31971.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Homeodomain PF00046.29 CBY31973.1 - 1.8e-19 69.3 1.1 1.8e-19 69.3 1.1 1.6 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 CBY31973.1 - 3.5e-09 36.7 30.2 4.3e-06 26.8 17.9 2.4 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CBY31973.1 - 9.8e-06 25.4 0.1 9e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain DUF3123 PF11321.8 CBY31973.1 - 0.0076 16.9 0.0 0.023 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3123) 7tm_2 PF00002.24 CBY31974.1 - 9.9e-22 77.4 15.4 6.4e-21 74.8 15.4 2.2 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 CBY31974.1 - 4.2e-08 33.6 5.6 4.2e-08 33.6 5.6 3.1 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif TMEM138 PF14935.6 CBY31974.1 - 0.094 13.4 1.2 2.7 8.7 0.5 2.7 2 0 0 2 2 2 0 Transmembrane protein 138 zf-3CxxC_2 PF17180.4 CBY31975.1 - 2.9e-22 79.2 13.6 2.9e-22 79.2 13.6 4.6 3 3 2 5 5 5 1 Zinc-binding domain Trypsin PF00089.26 CBY31976.1 - 1.7e-60 204.6 0.2 2.3e-60 204.1 0.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY31976.1 - 7.5e-06 26.9 0.0 3.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Phospholip_A2_1 PF00068.19 CBY31977.1 - 9.3e-18 64.7 10.4 1.6e-17 64.0 10.4 1.3 1 0 0 1 1 1 1 Phospholipase A2 SNF PF00209.18 CBY31978.1 - 1.3e-192 641.1 28.1 1.5e-192 640.9 28.1 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.15 CBY31979.1 - 2.2e-97 319.0 416.7 2.3e-10 40.5 11.1 23.4 23 1 1 24 24 24 22 Calcium-binding EGF domain EGF_3 PF12947.7 CBY31979.1 - 5.4e-46 154.5 392.6 9.4e-09 35.3 10.1 23.3 22 0 0 22 22 22 22 EGF domain cEGF PF12662.7 CBY31979.1 - 2.3e-44 148.9 241.7 4.7e-05 23.2 3.0 24.1 23 0 0 23 23 23 19 Complement Clr-like EGF-like EGF PF00008.27 CBY31979.1 - 4.4e-08 33.3 335.1 0.00069 19.9 6.2 24.2 22 0 0 22 22 22 14 EGF-like domain hEGF PF12661.7 CBY31979.1 - 6.2e-06 26.7 268.1 0.0065 17.1 1.3 26.3 25 1 0 25 25 25 16 Human growth factor-like EGF Imm53 PF15580.6 CBY31979.1 - 0.043 13.5 1.1 56 3.5 0.0 3.7 3 0 0 3 3 3 0 Immunity protein 53 Peptidase_C50 PF03568.17 CBY31980.1 - 2.1e-07 30.4 0.5 1.1e-06 28.1 0.5 2.2 1 0 0 1 1 1 1 Peptidase family C50 DUF4611 PF15387.6 CBY31980.1 - 0.85 9.9 12.3 5 7.4 12.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cob_adeno_trans PF01923.18 CBY31980.1 - 1.4 9.0 4.9 1 9.5 0.3 3.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase LRR_8 PF13855.6 CBY31981.1 - 5.2e-10 38.9 9.0 5.9e-06 26.0 0.9 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY31981.1 - 3.2e-08 33.7 12.2 2.7e-05 24.4 1.3 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY31981.1 - 0.089 13.4 10.4 19 6.3 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat ArgoN PF16486.5 CBY31982.1 - 1e-09 39.1 0.1 1.6e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of argonaute Piwi PF02171.17 CBY31983.1 - 6.6e-54 183.2 0.0 8.9e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 CBY31983.1 - 0.002 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain Band_7 PF01145.25 CBY31984.1 - 7.6e-28 97.7 1.3 1e-27 97.3 1.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY31984.1 - 0.047 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family PLDc PF00614.22 CBY31985.1 - 1.1e-15 57.1 0.1 1.9e-06 27.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CBY31985.1 - 3.2e-14 52.9 0.3 6.7e-08 32.5 0.1 2.8 2 0 0 2 2 2 2 PLD-like domain PH PF00169.29 CBY31985.1 - 1.4e-06 28.8 2.2 5.6e-05 23.6 2.2 3.2 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CBY31985.1 - 0.0048 17.3 7.6 0.027 14.9 0.4 4.0 3 1 1 4 4 4 1 Pleckstrin homology domain Glyco_hydro_6 PF01341.17 CBY31985.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 DUF4823 PF16105.5 CBY31985.1 - 0.045 13.6 1.3 0.28 11.1 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4823) Regulator_TrmB PF11495.8 CBY31985.1 - 0.11 11.6 0.1 0.51 9.5 0.1 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Ins_P5_2-kin PF06090.12 CBY31986.1 - 1.1e-58 199.2 0.7 1.3e-58 199.0 0.7 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase RhoGEF PF00621.20 CBY31987.1 - 4.8e-32 111.7 0.4 6.1e-32 111.3 0.4 1.1 1 0 0 1 1 1 1 RhoGEF domain Arm PF00514.23 CBY31989.1 - 2.3e-17 62.4 14.6 5.9e-09 35.7 0.0 10.0 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 CBY31989.1 - 0.00034 20.1 0.4 0.059 12.8 0.0 3.1 4 0 0 4 4 4 1 Family of unknown function (DUF5578) Arm_2 PF04826.13 CBY31989.1 - 0.0018 17.8 2.4 0.018 14.5 1.1 2.7 3 0 0 3 3 3 1 Armadillo-like V-ATPase_H_N PF03224.14 CBY31989.1 - 0.003 16.9 4.4 1.3 8.2 1.2 3.8 1 1 1 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CBY31989.1 - 0.0078 16.3 3.7 9.1 6.4 0.0 4.7 5 0 0 5 5 5 1 V-ATPase subunit H TetR_C_35 PF18556.1 CBY31989.1 - 0.019 15.1 1.0 3.6 7.8 0.1 2.9 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain DUF383 PF04063.14 CBY31989.1 - 0.079 12.6 0.7 5.7 6.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF383) CTNNBL PF08216.11 CBY31989.1 - 0.12 12.5 0.8 14 5.9 0.1 3.7 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear HEAT PF02985.22 CBY31989.1 - 0.28 11.6 1.3 1.3e+02 3.2 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat 3Beta_HSD PF01073.19 CBY31990.1 - 4.9e-38 130.7 0.0 5.8e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBY31990.1 - 1.2e-19 70.8 0.0 1.4e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBY31990.1 - 5.4e-14 52.0 0.0 9.3e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CBY31990.1 - 7.4e-10 39.0 0.0 8.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CBY31990.1 - 7e-09 35.2 0.0 8.7e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CBY31990.1 - 1e-05 25.1 0.2 2.4e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBY31990.1 - 7.9e-05 21.9 0.7 0.0013 17.9 0.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CBY31990.1 - 0.003 17.2 0.0 0.006 16.2 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CBY31990.1 - 0.032 13.7 0.0 0.067 12.6 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 CBY31991.1 - 6.2e-11 41.8 0.0 1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBY31991.1 - 5.2e-05 22.8 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY31991.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 CBY31992.1 - 2.4e-37 128.4 1.8 3.5e-37 127.9 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY31992.1 - 5.2e-28 98.0 0.0 3.5e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY31992.1 - 1.8e-21 76.1 0.0 3.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY31992.1 - 3.2e-08 33.9 0.0 4.6e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Carb_anhydrase PF00194.21 CBY31993.1 - 1.9e-78 263.6 0.1 2.2e-78 263.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CUB PF00431.20 CBY31994.1 - 8.9e-11 42.1 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 CUB domain PepSY_2 PF13670.6 CBY31996.1 - 0.16 12.0 0.1 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Homeodomain PF00046.29 CBY31997.1 - 2.3e-21 75.4 4.8 5e-21 74.3 4.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY31997.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CBY31997.1 - 0.021 14.3 0.3 0.043 13.3 0.3 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Glyco_hydro_9 PF00759.19 CBY31998.1 - 5.8e-232 770.4 11.9 1.6e-127 426.3 2.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 TRAM_LAG1_CLN8 PF03798.16 CBY31999.1 - 5.3e-16 59.0 10.1 5.9e-16 58.8 10.1 1.0 1 0 0 1 1 1 1 TLC domain DUF4956 PF16316.5 CBY31999.1 - 0.26 11.0 2.6 0.39 10.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) Sod_Fe_N PF00081.22 CBY32000.1 - 2e-32 111.5 1.0 3.5e-32 110.7 0.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CBY32000.1 - 1.8e-09 37.7 0.2 5.9e-09 36.0 0.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain TerB_C PF15615.6 CBY32001.1 - 0.023 15.0 0.9 0.036 14.4 0.9 1.3 1 0 0 1 1 1 0 TerB-C domain ESM4 PF15952.5 CBY32001.1 - 0.53 10.7 4.2 0.62 10.5 4.2 1.2 1 1 0 1 1 1 0 Enhancer of split M4 family SDF PF00375.18 CBY32002.1 - 5.5e-35 121.1 0.2 6.4e-35 120.9 0.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Stm1_N PF09598.10 CBY32003.1 - 0.039 14.8 3.3 0.14 13.0 3.3 2.0 1 0 0 1 1 1 0 Stm1 zf_C2HC_14 PF18574.1 CBY32003.1 - 0.11 12.3 1.0 0.26 11.1 1.0 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain IL5 PF02025.15 CBY32003.1 - 4.7 7.5 8.7 0.62 10.4 0.4 2.8 3 0 0 3 3 3 0 Interleukin 5 Acyl-CoA_dh_1 PF00441.24 CBY32004.1 - 5.8e-40 136.9 0.2 8.2e-40 136.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY32004.1 - 2.5e-26 92.5 0.1 8.9e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY32004.1 - 3.6e-26 91.2 0.0 6.4e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY32004.1 - 1.7e-06 28.4 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY32004.1 - 0.018 15.6 0.0 0.078 13.5 0.0 2.1 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal RT_RNaseH_2 PF17919.1 CBY32007.1 - 1.5e-10 41.0 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY32007.1 - 4.7e-10 39.4 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CBY32007.1 - 1.7e-07 31.4 0.0 1e-06 29.0 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 CBY32007.1 - 0.0003 21.3 0.0 0.0008 20.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY32007.1 - 0.065 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2616 PF11077.8 CBY32008.1 - 0.037 13.8 2.0 0.052 13.3 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) Noggin PF05806.12 CBY32009.1 - 2.2 8.1 5.2 2.9 7.7 5.2 1.3 1 0 0 1 1 1 0 Noggin PMP22_Claudin PF00822.20 CBY32010.1 - 0.00019 21.4 8.5 0.00019 21.4 8.5 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family DUF4271 PF14093.6 CBY32010.1 - 0.021 14.7 3.8 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF2207 PF09972.9 CBY32010.1 - 4.1 6.0 6.2 11 4.6 6.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_16 PF00722.21 CBY32011.1 - 2.3e-09 37.0 4.2 2.3e-09 37.0 4.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FSA_C PF10479.9 CBY32012.1 - 0.16 10.1 2.7 0.19 9.8 2.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sulfotransfer_2 PF03567.14 CBY32013.1 - 1.2e-15 58.1 3.6 2e-15 57.4 3.6 1.3 1 1 0 1 1 1 1 Sulfotransferase family Occludin_ELL PF07303.13 CBY32015.1 - 0.0045 17.7 15.0 0.11 13.3 0.3 4.1 2 1 0 3 3 3 2 Occludin homology domain Ntox1 PF15500.6 CBY32015.1 - 0.092 13.1 0.3 14 6.1 0.1 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Sbi-IV PF11621.8 CBY32015.1 - 0.33 11.3 5.6 6 7.3 0.3 3.7 3 1 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI PKcGMP_CC PF16808.5 CBY32015.1 - 2.6 8.0 10.0 1.3 8.9 1.0 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CUB PF00431.20 CBY32016.1 - 1.3e-12 48.0 0.0 2.2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 CUB domain Mtc PF03820.17 CBY32018.1 - 3.6e-93 312.0 0.0 4.1e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Trefoil PF00088.18 CBY32021.1 - 0.01 15.7 12.1 0.021 14.7 1.6 5.3 5 0 0 5 5 5 0 Trefoil (P-type) domain DUF4541 PF15074.6 CBY32023.1 - 0.0026 18.3 0.1 0.008 16.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Mt_ATP-synt_B PF05405.14 CBY32023.1 - 0.14 11.8 2.8 0.22 11.1 2.8 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RRM_1 PF00076.22 CBY32024.1 - 3.8e-10 39.4 0.0 4.5e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBY32024.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBY32024.1 - 0.077 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CBY32025.1 - 1.4e-09 37.6 0.1 3.1e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBY32025.1 - 0.022 14.7 0.0 0.067 13.1 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY32025.1 - 0.035 14.2 0.0 0.074 13.1 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 CBY32025.1 - 0.23 11.4 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif GPI2 PF06432.11 CBY32026.1 - 2.5e-16 59.9 21.1 3.8e-16 59.4 21.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Abhydrolase_1 PF00561.20 CBY32027.1 - 4.5e-19 69.1 0.1 7.4e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CBY32027.1 - 1.4e-11 43.8 0.0 3.5e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CBY32027.1 - 9.3e-07 28.3 0.0 4.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Connexin PF00029.19 CBY32029.1 - 1.3e-58 198.6 10.9 5.8e-38 131.0 0.3 2.5 2 1 1 3 3 3 2 Connexin Glyco_transf_7N PF13733.6 CBY32029.1 - 7.3e-46 155.1 0.0 1.7e-45 154.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY32029.1 - 4.1e-18 64.8 0.4 8.8e-18 63.7 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CUB PF00431.20 CBY32030.1 - 2e-06 28.1 0.0 3.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain Gly_transf_sug PF04488.15 CBY32033.1 - 2.3e-06 28.2 0.0 5.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CBY32033.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 CBY32033.1 - 0.024 14.8 1.0 0.024 14.8 1.0 1.8 2 1 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region ABC_membrane PF00664.23 CBY32034.1 - 9.1e-10 38.6 0.2 1.1e-09 38.4 0.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 CBY32035.1 - 3.2e-94 315.6 19.2 4.7e-53 180.6 11.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY32035.1 - 3.2e-74 247.9 1.4 1.4e-36 126.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CBY32035.1 - 4e-17 62.4 0.0 1.1e-07 31.6 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY32035.1 - 9.6e-10 38.9 0.1 0.0012 19.1 0.0 3.2 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBY32035.1 - 8.7e-09 35.5 0.1 0.0051 16.7 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 CBY32035.1 - 9.5e-08 32.1 0.3 0.0051 16.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY32035.1 - 4.1e-07 29.2 0.1 0.015 14.1 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY32035.1 - 1.5e-06 28.7 0.2 0.012 16.0 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBY32035.1 - 5.1e-06 26.9 1.0 0.68 10.4 0.1 4.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBY32035.1 - 2.2e-05 24.1 1.0 0.31 10.8 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 CBY32035.1 - 5.1e-05 23.1 1.3 0.27 10.9 0.2 3.5 2 2 0 2 2 2 2 AAA domain Rad17 PF03215.15 CBY32035.1 - 8.7e-05 22.5 0.6 0.18 11.7 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain SbcCD_C PF13558.6 CBY32035.1 - 0.00045 20.4 4.4 1.4 9.2 0.4 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 CBY32035.1 - 0.0005 19.6 0.1 0.3 10.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 CBY32035.1 - 0.001 18.3 0.1 0.44 9.6 0.1 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 CBY32035.1 - 0.0029 17.6 0.1 2.4 8.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY32035.1 - 0.0036 17.7 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.7 CBY32035.1 - 0.0038 16.2 0.1 2.2 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.12 CBY32035.1 - 0.005 16.1 2.1 0.13 11.6 0.0 3.1 4 0 0 4 4 4 1 Zeta toxin PRK PF00485.18 CBY32035.1 - 0.006 16.4 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_21 PF13304.6 CBY32035.1 - 0.016 15.0 0.2 8.6 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBY32035.1 - 0.017 14.7 0.0 8.4 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CBY32035.1 - 0.019 14.6 1.6 6.9 6.3 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 CBY32035.1 - 0.023 13.9 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 CBY32035.1 - 0.026 14.7 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBY32035.1 - 0.046 13.5 2.5 5.3 6.7 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 CBY32035.1 - 0.05 12.8 0.2 4 6.6 0.2 3.1 2 1 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 CBY32035.1 - 0.066 13.4 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 CBY32035.1 - 0.56 10.1 2.3 0.6 10.0 0.3 2.1 2 0 0 2 2 1 0 CDR ABC transporter AAA_23 PF13476.6 CBY32035.1 - 8.3 6.9 11.3 1.1 9.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain Ank_2 PF12796.7 CBY32036.1 - 2.5e-14 53.6 0.1 3.8e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32036.1 - 6.2e-14 51.9 0.1 1.7e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY32036.1 - 5.8e-13 49.1 0.2 1.5e-05 25.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY32036.1 - 1.5e-08 34.2 0.0 0.0017 18.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY32036.1 - 2.5e-08 34.0 0.3 0.00019 21.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Phospholip_A2_1 PF00068.19 CBY32037.1 - 1.7e-09 38.1 6.5 1.7e-09 38.1 6.5 2.4 2 0 0 2 2 2 1 Phospholipase A2 DUF3450 PF11932.8 CBY32038.1 - 0.0063 15.9 11.6 0.018 14.3 11.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) JAKMIP_CC3 PF16034.5 CBY32038.1 - 0.12 12.3 11.9 0.36 10.8 11.2 2.0 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF1515 PF07439.11 CBY32038.1 - 0.73 9.9 8.2 3 7.9 1.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) I_LWEQ PF01608.17 CBY32038.1 - 1 9.6 10.2 1.7 8.9 9.8 1.5 1 1 0 1 1 1 0 I/LWEQ domain Striatin PF08232.12 CBY32038.1 - 4 8.0 15.8 8.4 7.0 15.8 1.8 1 1 0 1 1 1 0 Striatin family TSC22 PF01166.18 CBY32038.1 - 7 7.0 14.6 0.17 12.2 1.7 3.1 2 1 2 4 4 4 0 TSC-22/dip/bun family Phospholip_A2_1 PF00068.19 CBY32039.1 - 2e-11 44.3 11.1 2e-11 44.3 11.1 2.0 2 0 0 2 2 2 1 Phospholipase A2 zf-RING_5 PF14634.6 CBY32040.1 - 1.8e-06 27.8 7.4 3e-06 27.1 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY32040.1 - 9.4e-06 25.9 6.9 1.4e-05 25.3 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY32040.1 - 7.3e-05 22.6 5.0 0.00051 19.8 5.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY32040.1 - 7.6e-05 22.7 7.2 0.00017 21.5 2.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY32040.1 - 0.00015 21.5 5.3 0.00028 20.7 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY32040.1 - 0.0043 16.9 8.1 0.0095 15.8 8.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) She9_MDM33 PF05546.11 CBY32040.1 - 0.039 13.8 0.9 0.049 13.4 0.9 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF2256 PF10013.9 CBY32040.1 - 1.1 9.4 0.1 1.1 9.4 0.1 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_4 PF15227.6 CBY32040.1 - 2 8.6 11.2 53 4.1 11.5 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FAD_binding_4 PF01565.23 CBY32041.1 - 1.1e-33 115.9 0.2 1.6e-33 115.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain SRCR PF00530.18 CBY32043.1 - 0.00012 22.5 2.6 0.00032 21.1 0.1 2.3 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain DUF1640 PF07798.11 CBY32044.1 - 0.16 12.0 21.1 0.056 13.5 9.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) DprA_WH PF17782.1 CBY32044.1 - 0.17 12.1 0.1 0.85 9.8 0.0 2.1 2 0 0 2 2 2 0 DprA winged helix domain GAS PF13851.6 CBY32044.1 - 0.3 10.4 25.1 0.55 9.6 24.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 CBY32044.1 - 0.83 9.2 8.2 1.1 8.7 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 CBY32044.1 - 3.8 6.0 13.7 5.7 5.4 13.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 CBY32044.1 - 3.9 6.7 17.8 0.46 9.8 12.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMEM237 PF15383.6 CBY32044.1 - 4.5 6.3 5.7 8.3 5.4 5.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 V_ATPase_I PF01496.19 CBY32044.1 - 5 4.9 10.8 6.9 4.5 10.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_hydro_28 PF00295.17 CBY32045.1 - 3.9e-29 101.7 0.1 5.8e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 zf-C3HC4_3 PF13920.6 CBY32047.1 - 6e-09 35.6 4.3 6e-09 35.6 4.3 3.2 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY32047.1 - 1.3e-07 31.5 6.9 1.3e-07 31.5 6.9 3.4 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY32047.1 - 1.2e-06 28.2 5.6 1.2e-06 28.2 5.6 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY32047.1 - 3.1e-05 23.7 7.4 3.1e-05 23.7 7.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY32047.1 - 6e-05 23.3 7.4 6e-05 23.3 7.4 3.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY32047.1 - 0.00018 21.3 14.5 0.00032 20.5 7.7 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY32047.1 - 0.001 19.0 2.9 0.001 19.0 2.9 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY32047.1 - 0.0014 18.3 6.1 0.0014 18.3 6.1 3.9 3 1 0 4 4 4 1 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 CBY32047.1 - 0.071 13.2 0.1 0.071 13.2 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) V_ATPase_I PF01496.19 CBY32047.1 - 0.073 11.0 1.2 0.082 10.8 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ETRAMP PF09716.10 CBY32047.1 - 1.1 9.4 5.7 0.22 11.6 1.7 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CoiA PF06054.11 CBY32048.1 - 0.0021 17.3 1.2 0.0022 17.2 1.2 1.0 1 0 0 1 1 1 1 Competence protein CoiA-like family ADK PF00406.22 CBY32050.1 - 4.9e-07 30.0 0.5 1.8e-06 28.1 0.3 1.8 2 0 0 2 2 2 1 Adenylate kinase DUF1993 PF09351.10 CBY32050.1 - 0.11 12.7 0.2 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Striatin PF08232.12 CBY32051.1 - 0.0079 16.8 18.5 0.44 11.1 8.1 2.6 1 1 1 2 2 2 2 Striatin family FapA PF03961.13 CBY32051.1 - 0.086 11.4 10.5 0.11 11.0 10.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mu-like_Pro PF10123.9 CBY32051.1 - 0.096 12.2 6.5 0.14 11.7 6.5 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein V_ATPase_I PF01496.19 CBY32051.1 - 0.11 10.5 7.2 0.12 10.3 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHE3 PF17078.5 CBY32051.1 - 0.12 12.1 14.8 0.21 11.3 14.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FAM76 PF16046.5 CBY32051.1 - 0.18 11.2 11.8 0.23 10.8 11.8 1.1 1 0 0 1 1 1 0 FAM76 protein MRPL52 PF18699.1 CBY32051.1 - 0.18 12.0 10.7 0.5 10.6 10.7 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Macoilin PF09726.9 CBY32051.1 - 3.9 5.9 12.9 5.3 5.5 12.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 CBY32051.1 - 4.3 6.6 21.7 0.7 9.2 8.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cyclin_N PF00134.23 CBY32052.1 - 5.7e-21 74.6 0.1 1.1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY32052.1 - 5e-13 49.2 0.4 5e-13 49.2 0.4 2.8 3 0 0 3 3 3 1 Cyclin, C-terminal domain LRR_8 PF13855.6 CBY32053.1 - 1.3e-40 136.9 24.1 6.8e-15 54.6 5.2 5.0 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 CBY32053.1 - 4.4e-15 55.5 22.3 1.3e-06 28.6 2.2 6.2 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY32053.1 - 8.9e-11 41.9 0.0 1.1e-07 31.9 0.0 2.8 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY32053.1 - 1.1e-08 34.8 3.8 0.0023 17.5 0.3 3.3 1 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CBY32053.1 - 7.6e-07 28.8 16.9 0.28 11.9 0.1 8.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY32053.1 - 0.41 10.8 12.6 3.8 7.8 0.2 6.2 7 0 0 7 7 7 0 Leucine Rich repeat DUF755 PF05501.11 CBY32053.1 - 6.2 7.1 10.7 13 6.1 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pkinase PF00069.25 CBY32054.1 - 1.7e-35 122.7 3.3 3.9e-35 121.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32054.1 - 1.1e-20 74.1 0.3 2.8e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF812 PF05667.11 CBY32054.1 - 0.0028 16.6 24.0 0.0044 16.0 24.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_13 PF13166.6 CBY32054.1 - 0.0046 15.7 16.3 0.0062 15.2 16.3 1.2 1 0 0 1 1 1 1 AAA domain RtcB PF01139.17 CBY32054.1 - 0.0083 15.4 1.5 0.013 14.7 1.5 1.3 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB GAD PF02938.14 CBY32054.1 - 0.013 15.7 7.0 0.41 10.9 0.3 2.6 2 0 0 2 2 2 0 GAD domain Elf4 PF07011.11 CBY32054.1 - 0.045 13.7 0.3 0.045 13.7 0.3 2.6 1 1 1 2 2 2 0 Early Flowering 4 domain Golgin_A5 PF09787.9 CBY32054.1 - 0.073 12.5 21.3 0.22 10.9 21.3 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 CBY32054.1 - 1.4 6.7 12.4 2.1 6.2 12.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CBY32054.1 - 2.9 7.2 19.1 13 5.0 17.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CBY32054.1 - 5 7.8 8.5 30 5.3 6.1 2.9 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.10 CBY32054.1 - 5.8 7.1 14.7 1.7 8.8 7.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 CBY32054.1 - 6.9 6.7 32.9 0.31 11.1 24.1 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Zip PF02535.22 CBY32056.1 - 1.6e-05 24.3 2.1 2e-05 24.0 2.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter TssN PF17555.2 CBY32056.1 - 0.002 17.5 1.4 0.0025 17.3 1.4 1.1 1 0 0 1 1 1 1 Type VI secretion system, TssN RMMBL PF07521.12 CBY32057.1 - 1.7e-11 43.9 0.0 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Arm PF00514.23 CBY32057.1 - 0.00013 21.9 0.0 1 9.5 0.0 4.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MH2 PF03166.14 CBY32059.1 - 1.4e-23 84.1 0.0 1.7e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 MH2 domain IRF-3 PF10401.9 CBY32059.1 - 0.065 13.0 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 HEAT PF02985.22 CBY32060.1 - 2.2e-31 105.2 18.7 0.0013 18.8 0.2 13.1 13 0 0 13 13 13 7 HEAT repeat HEAT_2 PF13646.6 CBY32060.1 - 5.5e-30 103.6 9.7 1.6e-07 31.6 0.3 6.6 3 2 4 7 7 7 7 HEAT repeats Cnd1 PF12717.7 CBY32060.1 - 1.6e-12 47.8 9.6 0.02 15.0 0.3 6.2 2 2 3 7 7 7 5 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBY32060.1 - 2.5e-12 47.0 5.9 0.085 13.4 0.0 7.0 7 3 2 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBY32060.1 - 1.1e-08 35.5 0.2 1.7 9.3 0.0 6.5 4 1 4 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBY32060.1 - 2.2e-08 33.1 11.0 0.00024 19.8 2.3 3.2 3 0 0 3 3 3 3 Adaptin N terminal region IFRD PF05004.13 CBY32060.1 - 5.8e-06 25.6 4.9 2.5e-05 23.5 0.0 3.7 3 3 1 4 4 4 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 CBY32060.1 - 7.5e-06 25.7 2.7 0.11 12.1 0.0 4.8 2 1 1 5 5 5 2 CLASP N terminal RTP1_C1 PF10363.9 CBY32060.1 - 0.00025 21.2 4.9 0.076 13.2 0.1 5.1 5 2 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 M11L PF11099.8 CBY32060.1 - 0.1 12.9 0.4 1.1 9.5 0.0 2.8 3 1 0 3 3 3 0 Apoptosis regulator M11L like WD40 PF00400.32 CBY32061.1 - 9.9e-29 99.0 10.5 3.8e-07 30.7 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBY32061.1 - 1.4e-27 95.7 0.8 9.2e-27 93.1 0.3 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.11 CBY32061.1 - 0.00016 21.7 2.3 0.0012 18.8 0.1 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBY32061.1 - 0.00071 19.8 2.8 0.11 12.9 0.1 3.9 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DBP10CT PF08147.12 CBY32061.1 - 0.15 12.3 0.6 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 DBP10CT (NUC160) domain DUF3689 PF12463.8 CBY32062.1 - 8.6e-110 366.9 2.2 8.6e-110 366.9 2.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) TFR_dimer PF04253.15 CBY32062.1 - 0.03 14.4 0.1 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Med23 PF11573.8 CBY32063.1 - 9.4e-229 762.4 38.7 1.1e-228 762.2 38.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 MRAP PF15183.6 CBY32063.1 - 0.1 12.6 0.0 0.4 10.6 0.0 2.1 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family MGAT2 PF05060.14 CBY32064.1 - 1.2e-87 294.3 1.7 1.4e-87 294.0 1.7 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Syndecan PF01034.20 CBY32065.1 - 3.8e-08 33.1 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Fe-ADH PF00465.19 CBY32066.1 - 7.8e-96 321.1 0.0 8.9e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBY32066.1 - 8.5e-12 45.3 0.0 6.5e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase bZIP_1 PF00170.21 CBY32067.1 - 2.8e-13 49.7 15.2 2.8e-13 49.7 15.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY32067.1 - 4.8e-07 29.7 13.5 4.8e-07 29.7 13.5 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY32067.1 - 2.1e-05 25.0 12.9 6.1e-05 23.5 9.8 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor RF-1 PF00472.20 CBY32067.1 - 0.01 15.7 4.8 0.04 13.9 2.1 2.2 2 0 0 2 2 2 0 RF-1 domain ZapB PF06005.12 CBY32067.1 - 0.015 15.7 8.5 0.015 15.7 8.5 2.5 2 1 1 3 3 3 0 Cell division protein ZapB YabA PF06156.13 CBY32067.1 - 0.016 15.8 5.4 0.31 11.7 3.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 CBY32067.1 - 0.029 14.6 2.9 0.065 13.5 2.9 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY32067.1 - 0.45 9.3 11.0 0.098 11.5 6.9 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 CBY32067.1 - 0.66 9.5 11.2 0.15 11.6 7.4 1.9 2 1 0 2 2 2 0 PspA/IM30 family Spc24 PF08286.11 CBY32067.1 - 0.84 9.9 8.4 0.21 11.8 4.0 2.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Pox_G5 PF04599.12 CBY32067.1 - 1.4 7.9 4.1 2.2 7.2 4.1 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Atg14 PF10186.9 CBY32067.1 - 1.7 7.7 10.3 0.5 9.4 6.4 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 CBY32067.1 - 2.4 7.7 9.8 0.31 10.6 4.5 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 HAUS6_N PF14661.6 CBY32067.1 - 3.8 7.0 8.6 0.88 9.1 5.3 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3552 PF12072.8 CBY32067.1 - 5.7 6.3 17.2 0.76 9.2 11.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Adhesin_P1_N PF18652.1 CBY32068.1 - 0.037 14.0 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain MRP-S26 PF14943.6 CBY32069.1 - 2.9e-14 53.3 6.6 2.9e-14 53.3 6.6 2.0 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 Prok-TraM PF09228.10 CBY32069.1 - 0.0067 16.8 1.4 0.02 15.3 1.4 1.8 1 0 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM DUF2654 PF10849.8 CBY32069.1 - 0.0097 16.1 1.4 0.018 15.2 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2654) FKBP_N PF01346.18 CBY32069.1 - 0.58 11.2 8.4 2.3 9.2 1.1 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2789 PF10982.8 CBY32069.1 - 0.81 9.9 4.6 0.3 11.3 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2789) SKA2 PF16740.5 CBY32070.1 - 0.019 14.8 1.5 0.036 13.8 1.5 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HALZ PF02183.18 CBY32070.1 - 0.12 12.7 0.8 0.27 11.5 0.8 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3450 PF11932.8 CBY32070.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ninjurin PF04923.12 CBY32071.1 - 4.7e-05 23.3 7.8 6.2e-05 22.9 7.8 1.2 1 0 0 1 1 1 1 Ninjurin Serinc PF03348.15 CBY32071.1 - 0.22 10.4 6.3 0.27 10.1 6.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2207 PF09972.9 CBY32071.1 - 0.45 9.2 1.0 0.5 9.1 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ist1 PF03398.14 CBY32073.1 - 2.5e-52 177.1 6.8 3e-52 176.9 6.8 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2624 PF11116.8 CBY32073.1 - 0.072 14.0 0.3 2.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) Galactosyl_T PF01762.21 CBY32075.1 - 1.4e-15 57.6 0.0 2.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase Gal-3-0_sulfotr PF06990.11 CBY32076.1 - 1.1e-27 96.9 1.7 6.3e-27 94.5 1.7 1.8 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase HLH PF00010.26 CBY32077.1 - 2.4e-14 53.0 0.0 3.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain VCX_VCY PF15231.6 CBY32077.1 - 0.0022 18.7 1.6 0.0055 17.4 1.6 1.6 1 0 0 1 1 1 1 Variable charge X/Y family Ion_trans PF00520.31 CBY32078.1 - 6.7e-25 87.7 12.9 1e-24 87.1 12.9 1.2 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CBY32078.1 - 2.4e-24 85.3 2.0 2.4e-24 85.3 2.0 1.9 2 0 0 2 2 2 1 Transient receptor ion channel II Ank_2 PF12796.7 CBY32078.1 - 2.7e-09 37.5 0.3 0.0028 18.2 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY32078.1 - 2.2e-06 28.1 0.1 0.032 14.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 CBY32078.1 - 4.6e-06 25.6 9.1 8.3e-06 24.7 9.1 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank_3 PF13606.6 CBY32078.1 - 6.1e-06 26.2 0.3 0.64 10.8 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY32078.1 - 0.00015 22.0 0.0 1.1 9.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY32078.1 - 0.0099 16.3 0.3 0.98 10.0 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeat ATG16 PF08614.11 CBY32078.1 - 4.7 7.4 18.3 0.58 10.4 13.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Kinesin PF00225.23 CBY32079.1 - 1.3e-84 283.9 0.6 7.5e-84 281.5 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY32079.1 - 1.4e-21 77.0 0.1 5.4e-19 68.6 0.0 3.2 2 0 0 2 2 2 1 Microtubule binding ATG16 PF08614.11 CBY32079.1 - 0.012 15.8 16.3 0.012 15.8 16.3 6.8 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBY32079.1 - 0.072 12.0 110.8 0.042 12.7 15.2 6.2 2 2 4 6 6 6 0 Spc7 kinetochore protein DUF4407 PF14362.6 CBY32079.1 - 0.31 10.4 72.7 1 8.7 12.6 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY32079.1 - 0.53 10.3 109.4 0.064 13.3 4.1 8.6 3 1 4 8 8 8 0 TPR/MLP1/MLP2-like protein PilJ PF13675.6 CBY32079.1 - 1.3 9.0 19.6 0.21 11.6 2.5 5.5 2 2 4 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.8 CBY32079.1 - 1.8 8.7 104.8 0.69 10.0 4.7 8.3 3 3 3 7 7 7 0 Afadin- and alpha -actinin-Binding Phospholip_A2_1 PF00068.19 CBY32081.1 - 9.1e-12 45.4 3.6 9.1e-12 45.4 3.6 1.6 2 0 0 2 2 2 1 Phospholipase A2 HEAT_EZ PF13513.6 CBY32082.1 - 0.054 14.0 0.2 10 6.7 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat EF-hand_1 PF00036.32 CBY32085.1 - 5.6e-05 22.4 1.0 0.055 13.0 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY32085.1 - 0.0006 19.6 0.9 2.2 8.2 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY32085.1 - 0.00073 19.3 5.0 0.12 12.4 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY32085.1 - 0.0029 18.0 1.9 0.029 14.8 1.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY32085.1 - 0.06 13.7 0.3 10 6.5 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Phage_int_SAM_3 PF14659.6 CBY32085.1 - 1 9.6 5.5 0.45 10.8 0.6 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Rer1 PF03248.13 CBY32086.1 - 0.0056 16.4 3.6 0.049 13.4 0.1 2.2 1 1 1 2 2 2 2 Rer1 family Lysis_col PF02402.16 CBY32086.1 - 0.0096 15.6 3.1 0.19 11.4 0.1 2.5 2 0 0 2 2 2 2 Lysis protein Calcyon PF06387.11 CBY32086.1 - 0.045 13.7 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) E1-E2_ATPase PF00122.20 CBY32086.1 - 0.54 9.8 5.8 0.62 9.6 0.2 2.3 1 1 0 2 2 2 0 E1-E2 ATPase Ctr PF04145.15 CBY32087.1 - 2.6e-18 67.1 13.0 1.2e-14 55.1 13.0 2.0 1 1 0 1 1 1 1 Ctr copper transporter family ThiW PF09512.10 CBY32087.1 - 0.0075 16.4 0.3 0.011 15.8 0.3 1.2 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) Innexin PF00876.18 CBY32089.1 - 2.1e-05 24.0 0.1 2.1e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 Innexin AWS PF17907.1 CBY32089.1 - 6 7.0 10.2 0.51 10.4 5.0 1.9 2 0 0 2 2 2 0 AWS domain ETRAMP PF09716.10 CBY32090.1 - 0.032 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF5345 PF17280.2 CBY32090.1 - 0.053 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Phospholip_A2_1 PF00068.19 CBY32091.1 - 1.4e-17 64.1 10.4 1.4e-17 64.1 10.4 2.1 1 1 1 2 2 2 2 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY32092.1 - 1.2e-18 67.6 13.2 1.2e-18 67.6 13.2 1.4 2 0 0 2 2 2 1 Phospholipase A2 CDP-OH_P_transf PF01066.21 CBY32093.1 - 1.6e-15 57.6 0.3 1.6e-15 57.6 0.3 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Colicin_V PF02674.16 CBY32093.1 - 0.0064 16.5 1.5 0.019 15.0 1.5 1.8 1 0 0 1 1 1 1 Colicin V production protein DCX PF03607.17 CBY32094.1 - 2.8e-09 36.9 0.0 7.5e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Doublecortin RRM_1 PF00076.22 CBY32095.1 - 7.5e-18 64.1 0.2 1.3e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32095.1 - 0.00039 20.5 0.1 0.0016 18.5 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CBY32095.1 - 0.038 13.6 0.1 0.075 12.6 0.0 1.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3088 PF11287.8 CBY32097.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3088) Cation_efflux PF01545.21 CBY32098.1 - 5.1e-43 147.1 13.0 6.3e-42 143.6 6.1 2.1 2 0 0 2 2 2 2 Cation efflux family DC_STAMP PF07782.13 CBY32098.1 - 0.044 13.6 1.0 0.33 10.8 0.2 2.3 2 0 0 2 2 2 0 DC-STAMP-like protein PRD1_DD PF11087.8 CBY32098.1 - 0.072 12.8 0.3 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery DUF3050 PF11251.8 CBY32100.1 - 8.9e-74 248.0 0.0 1e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) RCC1 PF00415.18 CBY32102.1 - 8.9e-74 243.9 17.3 3.3e-12 46.8 0.3 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CBY32102.1 - 1.8e-71 241.1 0.1 3.2e-71 240.3 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 CBY32102.1 - 1.3e-44 149.2 33.3 2.2e-10 40.0 0.9 7.7 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat PIRT PF15099.6 CBY32102.1 - 0.02 14.5 0.1 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family CdiA_C PF18451.1 CBY32102.1 - 0.14 12.4 1.1 0.64 10.3 1.0 2.2 1 1 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain MMS19_N PF14500.6 CBY32103.1 - 0.058 13.0 0.1 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II TPR_2 PF07719.17 CBY32104.1 - 3.3e-08 33.0 0.0 0.00021 21.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY32104.1 - 4.9e-06 26.1 0.1 0.0011 18.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY32104.1 - 7.9e-05 22.9 0.0 0.89 9.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY32104.1 - 8.1e-05 22.2 0.0 0.00082 19.0 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 CBY32104.1 - 0.00014 22.3 0.1 0.0052 17.3 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY32104.1 - 0.00036 21.1 0.0 0.075 13.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY32104.1 - 0.0032 17.9 0.0 0.021 15.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY32104.1 - 0.012 15.6 0.8 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 CBY32104.1 - 0.02 15.1 0.0 0.089 13.0 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBY32104.1 - 0.024 15.4 0.0 0.41 11.6 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY32104.1 - 0.07 13.4 3.6 0.15 12.3 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY32104.1 - 0.09 12.9 0.4 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Allexi_40kDa PF05549.11 CBY32104.1 - 0.1 12.1 4.6 0.072 12.6 0.5 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein LMBR1 PF04791.16 CBY32104.1 - 1 8.2 12.2 0.35 9.7 1.9 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Iwr1 PF08574.10 CBY32105.1 - 1.7e-07 32.2 17.4 1.7e-07 32.2 17.4 2.6 2 0 0 2 2 2 1 Transcription factor Iwr1 DUF5537 PF17690.1 CBY32106.1 - 0.00014 21.6 0.5 0.0003 20.5 0.5 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5537) Exonuc_X-T_C PF08411.10 CBY32106.1 - 0.0033 16.6 0.3 0.006 15.8 0.3 1.5 1 0 0 1 1 1 1 Exonuclease C-terminal Aa_trans PF01490.18 CBY32108.1 - 1.4e-46 159.0 38.8 1.4e-31 109.6 23.2 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein ER PF01133.17 CBY32109.1 - 3.2e-41 139.3 0.2 3.6e-41 139.1 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary HSR PF03172.13 CBY32109.1 - 0.019 15.1 0.3 0.027 14.6 0.3 1.2 1 0 0 1 1 1 0 HSR domain DUF4735 PF15882.5 CBY32109.1 - 0.059 12.8 0.1 0.074 12.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) PAPS_reduct PF01507.19 CBY32110.1 - 3.9 7.5 6.6 5.9 6.9 6.6 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HS1_rep PF02218.15 CBY32111.1 - 1.2e-54 182.3 40.2 1.2e-20 73.5 3.7 5.2 5 0 0 5 5 5 4 Repeat in HS1/Cortactin SH3_9 PF14604.6 CBY32111.1 - 3.9e-15 55.5 0.1 3.9e-15 55.5 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY32111.1 - 1.6e-14 53.2 1.5 2.6e-14 52.6 0.3 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY32111.1 - 3.1e-09 36.4 0.0 6.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain OMP_b-brl PF13505.6 CBY32111.1 - 4.5 7.3 8.4 1.4e+02 2.5 8.4 2.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain WD40 PF00400.32 CBY32112.1 - 9.2e-46 152.9 31.9 1.9e-07 31.6 0.2 10.3 10 0 0 10 10 10 8 WD domain, G-beta repeat Utp13 PF08625.11 CBY32112.1 - 5.7e-25 87.9 0.2 1.2e-24 86.9 0.2 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CBY32112.1 - 3.1e-22 78.7 5.0 1.1e-05 25.6 0.1 7.0 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY32112.1 - 4.6e-08 32.7 3.8 0.01 15.2 0.0 4.2 4 0 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 CBY32112.1 - 0.00019 21.4 0.0 0.13 12.1 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Peptidase_M13 PF01431.21 CBY32112.1 - 0.054 13.1 0.5 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Peptidase family M13 MCM_lid PF17855.1 CBY32112.1 - 0.083 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain Methuselah_N PF06652.12 CBY32112.1 - 0.29 11.0 1.6 0.71 9.8 0.9 1.9 2 0 0 2 2 2 0 Methuselah N-terminus ACBP PF00887.19 CBY32113.1 - 5.2e-19 68.2 0.2 8.1e-19 67.6 0.2 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein NRDE-2 PF08424.10 CBY32113.1 - 0.038 13.1 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Ank_4 PF13637.6 CBY32114.1 - 2.1e-23 82.4 0.7 5.5e-10 39.6 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY32114.1 - 4.6e-16 58.4 0.0 1.1e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CBY32114.1 - 1.4e-15 57.7 0.1 3.2e-14 53.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32114.1 - 1.6e-14 53.7 0.7 7.7e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY32114.1 - 6.2e-14 50.8 0.0 1.3e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat zf-LITAF-like PF10601.9 CBY32116.1 - 2.8 8.3 14.0 5.4 7.4 14.0 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain PXPV PF12778.7 CBY32117.1 - 0.086 12.7 17.0 0.22 11.5 17.0 1.6 1 1 0 1 1 1 0 PXPV repeat (3 copies) DnaI_N PF07319.11 CBY32119.1 - 0.41 11.3 6.9 0.72 10.6 0.4 2.8 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus XhlA PF10779.9 CBY32119.1 - 1.1 9.5 4.4 0.52 10.6 0.7 2.1 2 0 0 2 2 2 0 Haemolysin XhlA LcrG PF07216.12 CBY32119.1 - 9.9 6.2 8.4 3.9 7.5 0.1 3.6 4 0 0 4 4 4 0 LcrG protein PfkB PF00294.24 CBY32120.1 - 3.3e-57 194.1 0.1 4.3e-57 193.7 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CBY32120.1 - 6.6e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF5518 PF17647.1 CBY32120.1 - 0.067 13.3 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) ATP_synt_H PF05493.13 CBY32121.1 - 1.7e-18 66.8 8.2 2e-18 66.6 8.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit H N2227 PF07942.12 CBY32122.1 - 9.7e-82 274.2 0.0 1.3e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 CBY32122.1 - 0.008 16.8 0.0 0.065 13.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY32122.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBY32122.1 - 0.031 15.0 0.0 0.37 11.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Sec20 PF03908.13 CBY32122.1 - 0.042 13.7 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Sec20 Methyltransf_25 PF13649.6 CBY32122.1 - 0.12 13.0 0.0 1.7 9.4 0.0 2.4 1 1 0 2 2 2 0 Methyltransferase domain SYF2 PF08231.12 CBY32123.1 - 3.1e-42 144.7 16.5 3.1e-42 144.7 16.5 1.8 1 1 1 2 2 2 1 SYF2 splicing factor WW PF00397.26 CBY32124.1 - 2.9e-07 30.5 0.3 6.7e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 WW domain Ndc80_HEC PF03801.13 CBY32125.1 - 4.2e-18 65.4 0.7 3.3e-17 62.5 0.0 2.5 2 0 0 2 2 2 1 HEC/Ndc80p family zf-C4H2 PF10146.9 CBY32125.1 - 0.015 15.6 10.6 0.015 15.6 10.6 3.2 2 1 1 3 3 3 0 Zinc finger-containing protein KIAA1430 PF13879.6 CBY32125.1 - 0.26 12.1 24.5 0.17 12.7 6.9 3.4 3 0 0 3 3 3 0 KIAA1430 homologue YabA PF06156.13 CBY32125.1 - 4.9 7.8 30.1 4.3 8.0 6.0 4.3 2 1 1 3 3 3 0 Initiation control protein YabA GAS PF13851.6 CBY32125.1 - 6.5 6.0 41.8 0.022 14.1 10.5 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Collagen PF01391.18 CBY32126.1 - 5.2e-20 71.0 64.7 1.6e-08 34.2 22.4 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) SET PF00856.28 CBY32127.1 - 1.8e-19 70.8 0.5 1.8e-19 70.8 0.5 2.7 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CBY32127.1 - 5.7e-11 42.7 15.9 5.7e-11 42.7 15.9 3.7 3 1 0 3 3 3 1 CXC domain PRC2_HTH_1 PF18118.1 CBY32127.1 - 0.00081 20.2 0.0 0.00081 20.2 0.0 2.7 3 0 0 3 3 3 1 Polycomb repressive complex 2 tri-helical domain Myb_DNA-binding PF00249.31 CBY32127.1 - 0.021 15.0 0.8 0.69 10.2 0.0 3.4 4 0 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY32127.1 - 0.1 12.9 3.7 9.9 6.5 0.0 3.7 4 0 0 4 4 4 0 Myb-like DNA-binding domain CSD PF00313.22 CBY32128.1 - 1.6e-21 75.9 0.4 2.8e-21 75.1 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain KdpC PF02669.15 CBY32128.1 - 0.011 15.5 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 K+-transporting ATPase, c chain OB_RNB PF08206.11 CBY32128.1 - 0.044 13.5 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain Rrn6 PF10214.9 CBY32128.1 - 0.17 10.3 3.1 0.24 9.9 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SH3_9 PF14604.6 CBY32129.1 - 2.8e-13 49.5 0.4 5.9e-13 48.5 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY32129.1 - 3.2e-12 45.9 0.6 5.9e-12 45.0 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY32129.1 - 3.9e-11 42.5 0.0 7.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 CBY32129.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY32129.1 - 2.2e-08 34.6 0.0 3.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY32129.1 - 2.1e-07 31.1 0.0 7.1e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CBY32129.1 - 3.6e-07 30.0 0.0 2.3e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY32129.1 - 1.2e-06 28.7 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TFR_dimer PF04253.15 CBY32130.1 - 1.7e-05 24.9 0.0 2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain DUF4492 PF14899.6 CBY32132.1 - 0.0033 17.3 0.1 0.0044 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4492) VWA_N2 PF16164.5 CBY32136.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 VWA N-terminal RCC1 PF00415.18 CBY32137.1 - 6.5e-60 199.6 29.5 1.4e-12 48.0 0.5 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 CBY32137.1 - 8.7e-58 196.2 0.0 1.3e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1_2 PF13540.6 CBY32137.1 - 6e-25 86.5 34.7 1.1e-09 37.8 1.0 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 CBY32137.1 - 0.053 14.4 7.2 3 8.9 0.1 4.8 5 1 1 6 6 6 0 WD domain, G-beta repeat Ceramidase PF05875.12 CBY32139.1 - 9.3e-52 176.0 13.5 1.1e-51 175.8 13.5 1.0 1 0 0 1 1 1 1 Ceramidase Rhamno_transf PF11316.8 CBY32140.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase Mucin2_WxxW PF13330.6 CBY32142.1 - 1.6e-18 67.3 0.1 4.4e-16 59.5 0.0 3.4 3 1 0 3 3 3 1 Mucin-2 protein WxxW repeating region V_cholerae_RfbT PF05575.11 CBY32142.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein RCC1 PF00415.18 CBY32143.1 - 1.1e-72 240.4 18.6 7.4e-13 48.9 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY32143.1 - 8.5e-30 101.9 33.8 2.6e-09 36.6 0.2 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.21 CBY32144.1 - 5.2e-19 67.2 2.3 0.00041 20.2 0.0 6.3 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 CBY32144.1 - 0.00064 19.4 0.1 0.013 15.1 0.1 2.7 1 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CBY32144.1 - 0.02 15.0 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 Strictosidine synthase RNase_PH PF01138.21 CBY32145.1 - 4.5e-20 72.5 0.0 1e-19 71.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBY32145.1 - 2.8e-12 46.5 0.0 5.1e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RIO1 PF01163.22 CBY32146.1 - 7e-61 205.1 0.0 1.8e-60 203.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY32146.1 - 0.00013 22.0 0.0 0.0073 16.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY32146.1 - 0.0033 16.2 0.2 0.0075 15.1 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase UIM PF02809.20 CBY32146.1 - 0.0043 16.9 1.3 0.022 14.7 1.3 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif TFIIB PF00382.19 CBY32147.1 - 2.8e-43 145.8 2.8 7.6e-22 77.2 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CBY32147.1 - 2.8e-12 45.9 0.1 5.9e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CBY32147.1 - 7.7e-06 25.7 0.1 0.0079 15.9 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY32147.1 - 0.00012 22.1 0.1 0.37 10.9 0.0 2.4 1 1 1 2 2 2 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 CBY32147.1 - 0.086 12.4 0.1 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 RB_B PF01857.20 CBY32147.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.8 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain DUF2039 PF10217.9 CBY32147.1 - 2.5 8.5 5.2 1.7 9.0 1.6 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) NUDIX PF00293.28 CBY32148.1 - 3.5e-14 53.0 0.0 4.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_1 PF00441.24 CBY32149.1 - 4.3e-41 140.6 8.8 3.3e-36 124.7 3.5 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY32149.1 - 1.7e-24 85.9 0.0 6.2e-24 84.0 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY32149.1 - 6.9e-23 81.5 0.1 2.4e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY32149.1 - 2.1e-10 41.0 2.4 3.1e-08 34.0 0.2 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain PKcGMP_CC PF16808.5 CBY32151.1 - 1.5 8.8 6.7 0.1 12.5 1.0 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Methyltransf_21 PF05050.12 CBY32152.1 - 2.3e-09 37.5 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3098 PF11297.8 CBY32152.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Pkinase PF00069.25 CBY32153.1 - 1.9e-09 37.3 0.8 4.9e-09 35.9 0.8 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32153.1 - 4.4e-06 26.2 0.0 9.2e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L4 PF00573.22 CBY32154.1 - 1.9e-25 89.7 0.6 2.3e-25 89.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CH PF00307.31 CBY32155.1 - 5.2e-75 248.6 2.9 2.9e-19 69.3 0.1 5.2 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY32155.1 - 3.9e-05 23.4 0.1 0.025 14.4 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain An_peroxidase PF03098.15 CBY32157.1 - 1.5e-100 337.3 0.0 1.8e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PT PF04886.12 CBY32157.1 - 0.15 11.6 49.4 0.04 13.5 26.1 2.6 1 1 1 2 2 2 0 PT repeat AJAP1_PANP_C PF15298.6 CBY32158.1 - 0.1 12.8 12.7 0.073 13.3 10.9 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus SSP160 PF06933.11 CBY32158.1 - 0.14 10.4 20.2 0.21 9.7 20.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 CBY32158.1 - 0.36 8.9 9.8 0.47 8.5 9.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 CBY32158.1 - 1.3 7.0 9.3 1.7 6.5 9.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RhoGEF PF00621.20 CBY32160.1 - 1e-28 100.8 6.4 1e-28 100.8 6.4 2.0 3 0 0 3 3 3 1 RhoGEF domain DUF3388 PF11868.8 CBY32160.1 - 0.014 14.7 0.5 0.029 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Septin PF00735.18 CBY32161.1 - 9.8e-66 221.9 9.9 5.3e-52 176.8 1.1 2.8 3 0 0 3 3 3 2 Septin GTP_EFTU PF00009.27 CBY32161.1 - 0.048 13.2 3.1 1.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.15 CBY32161.1 - 1.9 8.0 8.0 4.3 6.8 8.0 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Trypsin PF00089.26 CBY32162.1 - 2.2e-52 178.1 0.0 3.4e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY32162.1 - 3.9e-18 65.6 28.1 2.7e-12 46.8 8.5 3.9 3 2 1 4 4 4 2 Kringle domain Trypsin_2 PF13365.6 CBY32162.1 - 0.0014 19.6 0.0 0.0023 18.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Inositol_P PF00459.25 CBY32163.1 - 1.5e-36 126.4 0.0 1.8e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family PspB PF06667.12 CBY32163.1 - 0.0067 16.5 0.3 0.015 15.3 0.3 1.6 1 0 0 1 1 1 1 Phage shock protein B PhoPQ_related PF10142.9 CBY32164.1 - 1.8e-58 198.0 4.1 8.9e-58 195.7 4.1 1.8 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein PA PF02225.22 CBY32166.1 - 1.6e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 PA domain Trypsin PF00089.26 CBY32167.1 - 7.4e-59 199.2 0.5 1.5e-58 198.3 0.5 1.5 1 0 0 1 1 1 1 Trypsin EGF_CA PF07645.15 CBY32167.1 - 4.6e-15 55.5 27.6 7.1e-11 42.1 9.8 7.8 5 2 3 8 8 8 3 Calcium-binding EGF domain EGF PF00008.27 CBY32167.1 - 5.6e-12 45.7 89.7 3.5e-06 27.2 10.3 7.3 7 0 0 7 7 7 5 EGF-like domain EGF_3 PF12947.7 CBY32167.1 - 4.7e-07 29.9 25.0 5.7e-05 23.2 6.9 7.2 6 0 0 6 6 6 2 EGF domain FXa_inhibition PF14670.6 CBY32167.1 - 0.00012 22.2 62.6 0.03 14.6 10.5 6.8 3 2 2 5 5 5 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY32167.1 - 0.0005 20.0 12.5 0.0013 18.7 5.7 6.3 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF_2 PF07974.13 CBY32167.1 - 0.0012 19.2 10.6 0.0012 19.2 10.6 7.2 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.7 CBY32167.1 - 0.0049 17.5 6.8 0.0049 17.5 6.8 8.4 9 1 0 9 9 9 4 Human growth factor-like EGF DUF1986 PF09342.11 CBY32167.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Plasmod_Pvs28 PF06247.11 CBY32167.1 - 0.26 11.6 38.5 0.049 13.9 3.2 5.8 4 0 0 4 4 4 0 Pvs28 EGF domain LepB_GAP_N PF18172.1 CBY32168.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 LepB GAP domain N-terminal subdomain YL1 PF05764.13 CBY32169.1 - 0.00071 19.8 16.4 0.00098 19.3 16.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SRP-alpha_N PF04086.13 CBY32169.1 - 0.64 9.9 16.4 0.89 9.4 16.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4551 PF15087.6 CBY32169.1 - 6.5 5.5 5.9 7.5 5.3 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Gal-3-0_sulfotr PF06990.11 CBY32170.1 - 1.3e-31 109.9 2.1 2.1e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Chordopox_G3 PF06129.12 CBY32170.1 - 0.16 12.7 1.5 0.24 12.1 0.2 1.9 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Med30 PF11315.8 CBY32170.1 - 0.57 10.4 3.4 11 6.2 0.2 2.5 1 1 1 2 2 2 0 Mediator complex subunit 30 Abhydrolase_3 PF07859.13 CBY32171.1 - 6.2e-44 150.4 0.0 4.3e-35 121.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY32171.1 - 5.4e-07 28.9 0.0 1.7e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CBY32171.1 - 0.0027 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CBY32171.1 - 0.021 14.4 0.1 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 CBY32171.1 - 0.032 13.1 0.0 0.078 11.8 0.0 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 CBY32171.1 - 0.061 13.1 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 CBY32171.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) GlpM PF06942.12 CBY32171.1 - 0.13 12.7 0.0 0.4 11.1 0.0 1.8 2 0 0 2 2 2 0 GlpM protein AXE1 PF05448.12 CBY32171.1 - 0.13 10.9 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 CBY32171.1 - 0.18 11.6 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Sulfate_transp PF00916.20 CBY32172.1 - 1.9e-08 33.5 3.9 2.1e-08 33.3 3.9 1.0 1 0 0 1 1 1 1 Sulfate permease family TALPID3 PF15324.6 CBY32174.1 - 0.26 8.9 0.1 0.29 8.8 0.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Imm31 PF15591.6 CBY32174.1 - 0.27 11.1 1.4 4 7.4 0.1 2.7 2 1 1 3 3 3 0 Immunity protein 31 RVT_1 PF00078.27 CBY32176.1 - 1.7e-29 103.0 0.5 7.8e-29 100.8 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CBY32176.1 - 0.00041 20.2 0.0 0.0025 17.7 0.0 2.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4508 PF14969.6 CBY32176.1 - 0.041 14.1 1.7 0.37 11.1 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) 7tm_1 PF00001.21 CBY32177.1 - 0.00046 19.6 1.4 0.00065 19.1 1.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Spo7 PF03907.13 CBY32177.1 - 0.1 12.1 0.5 0.14 11.7 0.5 1.2 1 0 0 1 1 1 0 Spo7-like protein DHHC PF01529.20 CBY32179.1 - 3.2e-37 127.6 11.3 3.2e-37 127.6 11.3 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Imm17 PF15562.6 CBY32179.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.7 3 0 0 3 3 3 0 Immunity protein 17 DUF4131 PF13567.6 CBY32179.1 - 0.28 10.8 1.6 2.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) OppC_N PF12911.7 CBY32179.1 - 0.53 10.3 5.4 7.4 6.6 0.1 2.7 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Nup54_57_C PF18570.1 CBY32180.1 - 3.2 7.4 9.7 8.9 6.0 2.3 3.1 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain TPT PF03151.16 CBY32181.1 - 1.6e-20 73.6 16.0 2e-20 73.3 16.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY32181.1 - 1.2e-08 35.3 23.3 7.8e-05 22.9 5.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBY32181.1 - 4.1e-07 29.5 17.9 5.4e-07 29.1 17.9 1.2 1 0 0 1 1 1 1 UAA transporter family Peptidase_A8 PF01252.18 CBY32181.1 - 5.4e-05 23.4 2.3 5.4e-05 23.4 2.3 2.8 1 1 0 2 2 2 1 Signal peptidase (SPase) II Phage_holin_3_3 PF16083.5 CBY32181.1 - 0.0053 16.9 1.8 0.055 13.6 0.4 2.6 2 0 0 2 2 2 1 LydA holin phage, holin superfamily III SLC35F PF06027.12 CBY32181.1 - 0.011 15.2 12.9 0.18 11.2 0.3 2.4 2 1 1 3 3 3 0 Solute carrier family 35 EF-hand_7 PF13499.6 CBY32183.1 - 1.7e-12 47.6 17.3 1.6e-06 28.4 2.0 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY32183.1 - 1.2e-08 34.2 7.4 1.9e-05 24.2 0.9 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY32183.1 - 4.5e-08 32.1 11.4 6.8e-05 22.1 2.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CBY32183.1 - 7.9e-06 25.6 16.5 0.036 13.9 1.5 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CBY32183.1 - 0.0018 17.7 2.2 0.0018 17.7 2.2 2.3 2 0 0 2 2 2 1 EF hand Pep1_7 PF17232.2 CBY32183.1 - 0.03 14.8 0.7 0.06 13.8 0.7 1.5 1 0 0 1 1 1 0 Elicitor peptide 1-7 EF-hand_4 PF12763.7 CBY32183.1 - 0.034 14.1 0.6 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY32183.1 - 0.51 10.7 2.8 1.3 9.4 0.5 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sulfotransfer_2 PF03567.14 CBY32184.1 - 9.7e-42 143.6 0.9 1.2e-41 143.3 0.9 1.1 1 0 0 1 1 1 1 Sulfotransferase family SH2 PF00017.24 CBY32187.1 - 3.7e-05 23.7 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain LuxC PF05893.14 CBY32187.1 - 0.078 12.0 0.1 0.092 11.8 0.1 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cbl_N3 PF02762.14 CBY32187.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain LRR_8 PF13855.6 CBY32188.1 - 1.3e-13 50.5 2.4 4.2e-06 26.4 0.2 3.2 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY32188.1 - 1.5e-10 41.1 5.0 3.2e-05 24.2 0.2 4.0 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY32188.1 - 2.1e-07 30.9 0.1 3.1e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY32188.1 - 0.0091 15.5 1.2 0.069 12.7 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY32188.1 - 0.028 14.9 2.4 6.8 7.7 1.1 4.2 2 1 0 2 2 2 0 Leucine Rich Repeat TFIIA PF03153.13 CBY32189.1 - 0.13 12.2 12.5 0.17 11.9 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cse1 PF08506.10 CBY32189.1 - 0.19 10.5 0.2 0.25 10.1 0.2 1.1 1 0 0 1 1 1 0 Cse1 Sulfotransfer_3 PF13469.6 CBY32190.1 - 7.9e-05 23.1 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY32190.1 - 0.00025 20.6 0.1 0.00033 20.2 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain DUF4363 PF14276.6 CBY32190.1 - 0.093 12.9 0.5 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) MT PF12777.7 CBY32191.1 - 0.00092 18.3 1.7 0.85 8.6 0.3 2.9 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor IFT46_B_C PF12317.8 CBY32191.1 - 0.17 11.6 1.8 1.4 8.6 0.2 2.7 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Med29 PF11568.8 CBY32192.1 - 0.0072 16.6 2.4 0.014 15.6 2.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 29 Choline_kinase PF01633.20 CBY32193.1 - 1.4e-08 34.6 0.2 4.2e-08 33.0 0.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY32193.1 - 1.2e-06 28.6 0.2 1.7e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY32193.1 - 0.0002 20.8 0.9 0.00034 20.0 0.9 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase AvrPphF-ORF-2 PF09143.10 CBY32193.1 - 0.18 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AvrPphF-ORF-2 EGF_CA PF07645.15 CBY32194.1 - 4.4e-31 106.8 106.1 3.6e-07 30.3 4.2 7.4 7 0 0 7 7 7 6 Calcium-binding EGF domain EGF_3 PF12947.7 CBY32194.1 - 4.3e-09 36.4 88.8 0.0018 18.4 10.2 7.2 6 1 0 6 6 6 5 EGF domain cEGF PF12662.7 CBY32194.1 - 6.3e-07 29.2 33.8 0.0001 22.2 2.5 7.5 6 2 0 6 6 6 3 Complement Clr-like EGF-like EGF PF00008.27 CBY32194.1 - 0.00096 19.4 87.3 0.25 11.7 4.6 7.6 5 2 3 8 8 8 5 EGF-like domain FXa_inhibition PF14670.6 CBY32194.1 - 0.0039 17.4 21.5 0.016 15.5 7.7 6.8 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY32194.1 - 0.019 15.2 82.4 0.025 14.9 9.6 7.1 4 2 1 6 6 6 0 Pvs28 EGF domain hEGF PF12661.7 CBY32194.1 - 0.056 14.1 5.5 0.056 14.1 5.5 9.0 9 1 0 9 9 9 0 Human growth factor-like EGF Pkinase_Tyr PF07714.17 CBY32195.1 - 3.9e-86 288.5 0.0 5.1e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY32195.1 - 1.8e-39 135.7 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY32195.1 - 1.2e-21 76.5 0.0 2.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY32195.1 - 4.8e-17 61.3 0.1 9.3e-17 60.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY32195.1 - 8.1e-14 51.2 0.0 1.5e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY32195.1 - 3.3e-10 39.5 0.2 7.9e-10 38.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_10 PF17902.1 CBY32195.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 SH3 domain Haspin_kinase PF12330.8 CBY32195.1 - 0.062 12.2 0.0 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain SH3_3 PF08239.11 CBY32195.1 - 0.064 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1751 PF08551.10 CBY32196.1 - 2.6e-21 76.0 3.1 2.6e-21 76.0 3.1 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ubiquitin_2 PF14560.6 CBY32198.1 - 3.3e-26 91.6 0.0 7.2e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CBY32198.1 - 1.4e-23 82.7 0.6 2.6e-23 81.8 0.6 1.5 1 0 0 1 1 1 1 CAP-Gly domain CFAP91 PF14738.6 CBY32199.1 - 6.7e-52 175.6 15.2 6.7e-52 175.6 15.2 3.0 2 1 2 4 4 4 1 Cilia- and flagella-associated protein 91 Cas_Cas6 PF01881.16 CBY32199.1 - 0.23 12.0 2.0 0.56 10.8 2.0 1.7 1 0 0 1 1 1 0 CRISPR associated protein Cas6 DUF2935 PF11155.8 CBY32199.1 - 4.6 7.6 8.1 2.3 8.6 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 CBY32200.1 - 2.5e-67 227.0 0.0 2.9e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32200.1 - 2.3e-51 174.6 0.0 2.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY32200.1 - 8.2e-08 31.4 0.0 9.9e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY32200.1 - 0.00012 21.1 0.9 0.002 17.2 0.9 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY32200.1 - 0.008 15.5 0.1 0.38 10.0 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CBY32200.1 - 0.054 13.4 0.0 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abi_2 PF07751.11 CBY32200.1 - 0.12 12.6 0.2 0.37 11.1 0.0 1.8 2 1 0 2 2 2 0 Abi-like protein TFIIS_M PF07500.14 CBY32201.1 - 8.1e-36 122.9 2.1 8.1e-36 122.9 2.1 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CBY32201.1 - 3.1e-18 65.3 7.2 5e-18 64.7 7.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CBY32201.1 - 2e-11 43.7 2.3 2.4e-11 43.5 0.6 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain AreA_N PF07573.11 CBY32201.1 - 0.013 16.1 1.1 0.034 14.8 0.5 2.0 2 1 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus Ribosomal_60s PF00428.19 CBY32201.1 - 1.4 9.5 8.1 3.1 8.4 6.5 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF775 PF05603.12 CBY32201.1 - 3 7.3 6.6 0.64 9.5 1.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF775) zf-HIT PF04438.16 CBY32202.1 - 0.029 14.2 8.7 0.029 14.2 8.7 1.8 2 0 0 2 2 2 0 HIT zinc finger Tnp_zf-ribbon_2 PF13842.6 CBY32202.1 - 0.36 11.7 6.3 0.13 13.0 2.2 2.2 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-MYST PF17772.1 CBY32202.1 - 2.9 7.6 8.5 1.8 8.3 6.3 1.8 2 0 0 2 2 2 0 MYST family zinc finger domain FoP_duplication PF13865.6 CBY32202.1 - 6.8 7.3 18.7 11 6.6 18.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Glyco_hydro_20 PF00728.22 CBY32203.1 - 5e-79 266.2 0.1 7.7e-79 265.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CBY32203.1 - 5.9e-15 56.1 0.0 1.1e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CBY32203.1 - 1.9e-07 31.9 0.0 3.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Sulfotransfer_1 PF00685.27 CBY32204.1 - 1.1e-15 57.9 0.0 8.9e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY32204.1 - 5e-11 43.4 0.0 1.9e-07 31.7 0.0 2.6 3 0 0 3 3 3 2 Sulfotransferase family Collagen PF01391.18 CBY32206.1 - 8.5e-19 67.1 66.4 7.2e-10 38.5 29.2 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY32206.1 - 2e-14 54.2 0.3 3.1e-14 53.6 0.3 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY32206.1 - 1.4e-10 41.8 0.0 7.2e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain RHD3 PF05879.12 CBY32206.1 - 0.0064 14.7 0.6 0.0086 14.3 0.6 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Tetraspanin PF00335.20 CBY32207.1 - 9.8e-06 25.4 0.6 9.8e-06 25.4 0.6 1.9 2 0 0 2 2 2 1 Tetraspanin family Mucin PF01456.17 CBY32207.1 - 0.0082 16.1 0.3 0.0082 16.1 0.3 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein SUR7 PF06687.12 CBY32207.1 - 0.14 11.8 11.7 2.3 7.8 7.5 2.5 2 0 0 2 2 2 0 SUR7/PalI family PGF-CTERM PF18204.1 CBY32207.1 - 2.3 8.3 10.5 0.14 12.2 2.8 2.4 2 0 0 2 2 2 0 PGF-CTERM motif CUB PF00431.20 CBY32208.1 - 3.5e-11 43.4 0.1 7.5e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 CUB domain BshC PF10079.9 CBY32208.1 - 0.2 10.4 2.8 0.33 9.7 2.8 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC VWA_3 PF13768.6 CBY32209.1 - 3.5e-15 56.3 0.2 1.3e-14 54.4 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY32209.1 - 3.1e-14 53.5 0.4 1.5e-13 51.3 0.2 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CBY32209.1 - 1e-12 48.7 1.4 3.2e-12 47.1 1.4 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 CBY32209.1 - 0.00038 20.7 0.5 0.0022 18.2 0.1 2.4 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain CSD PF00313.22 CBY32211.1 - 3.1e-30 103.8 12.7 1.6e-08 34.3 0.4 6.5 7 0 0 7 7 7 4 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBY32211.1 - 5.2e-08 32.7 2.7 0.2 11.6 0.1 3.9 3 1 0 3 3 3 3 S1-like S1 PF00575.23 CBY32211.1 - 1.5e-05 25.2 2.4 0.0032 17.8 0.1 4.0 3 0 0 3 3 3 1 S1 RNA binding domain Rho_RNA_bind PF07497.12 CBY32211.1 - 0.00066 19.5 0.0 0.78 9.6 0.0 3.3 3 0 0 3 3 3 2 Rho termination factor, RNA-binding domain CusF_Ec PF11604.8 CBY32211.1 - 0.0072 16.3 1.1 9.8 6.2 0.0 4.1 4 0 0 4 4 4 1 Copper binding periplasmic protein CusF OB_RNB PF08206.11 CBY32211.1 - 0.018 14.7 8.5 1.3 8.7 0.1 3.9 4 0 0 4 4 4 0 Ribonuclease B OB domain Nsp1 PF11501.8 CBY32211.1 - 0.18 11.9 0.1 43 4.2 0.0 3.2 3 0 0 3 3 3 0 Non structural protein Nsp1 WD40 PF00400.32 CBY32214.1 - 0.12 13.3 0.9 22 6.1 0.0 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat WD40_like PF17005.5 CBY32214.1 - 0.13 11.6 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Imm3 PF14425.6 CBY32214.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 CAF1A PF12253.8 CBY32217.1 - 6.5e-20 71.1 12.8 6.5e-20 71.1 12.8 8.8 7 2 2 9 9 9 1 Chromatin assembly factor 1 subunit A TPR_12 PF13424.6 CBY32218.1 - 3.6e-17 62.4 44.3 0.0021 18.3 0.4 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBY32218.1 - 3.2e-13 48.9 9.2 0.012 15.4 0.1 9.8 11 0 0 11 11 11 3 Tetratricopeptide repeat CHAT PF12770.7 CBY32218.1 - 1.9e-12 47.2 0.4 3e-06 26.9 0.0 3.1 2 1 0 3 3 3 2 CHAT domain TPR_2 PF07719.17 CBY32218.1 - 2.1e-11 43.0 27.4 0.012 15.6 0.2 11.3 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY32218.1 - 2.7e-11 42.7 14.9 0.0089 16.2 0.1 10.3 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY32218.1 - 1.1e-10 40.7 16.0 0.0013 18.7 0.2 8.9 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 CBY32218.1 - 4.4e-07 29.9 22.4 0.35 11.6 0.4 9.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY32218.1 - 8.1e-06 26.4 33.4 0.0017 19.0 4.3 8.4 8 1 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY32218.1 - 7e-05 23.3 38.0 0.19 12.6 0.1 11.7 13 0 0 13 13 11 2 Tetratricopeptide repeat PhageMin_Tail PF10145.9 CBY32218.1 - 0.00034 20.5 0.2 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 Phage-related minor tail protein SRP_TPR_like PF17004.5 CBY32218.1 - 0.00035 20.6 2.7 0.0044 17.0 0.1 3.6 3 1 0 3 3 3 1 Putative TPR-like repeat ANAPC3 PF12895.7 CBY32218.1 - 0.00096 19.3 30.6 0.0068 16.6 1.2 7.7 7 1 2 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY32218.1 - 0.0049 17.4 0.9 0.0049 17.4 0.9 9.2 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY32218.1 - 0.037 14.4 2.0 0.83 10.2 0.0 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY32218.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 CBY32218.1 - 0.15 12.8 21.5 0.65 10.8 0.0 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat Clathrin PF00637.20 CBY32218.1 - 0.15 11.9 11.0 0.95 9.3 2.2 4.1 4 2 0 4 4 3 0 Region in Clathrin and VPS TPR_10 PF13374.6 CBY32218.1 - 0.85 9.6 34.1 1.2 9.1 0.2 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat HEAT_2 PF13646.6 CBY32218.1 - 4.4 7.8 19.3 1.8 9.0 0.1 6.2 5 2 3 8 8 7 0 HEAT repeats Ras PF00071.22 CBY32219.1 - 2.7e-67 225.4 1.0 3.3e-67 225.1 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY32219.1 - 6.5e-38 129.6 0.1 1.1e-37 128.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY32219.1 - 2.1e-17 63.2 0.2 2.4e-17 62.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY32219.1 - 2.9e-06 26.9 1.7 4.3e-06 26.4 0.3 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY32219.1 - 7.8e-06 25.9 1.5 0.055 13.4 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBY32219.1 - 8e-06 25.4 0.1 9.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY32219.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY32219.1 - 2.5e-05 23.8 0.1 3.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CBY32219.1 - 0.01 15.3 0.1 0.066 12.7 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CBY32219.1 - 0.011 15.5 0.1 0.55 10.0 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBY32219.1 - 0.036 13.6 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 CBY32219.1 - 0.04 14.3 0.0 0.76 10.2 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) LANC_like PF05147.13 CBY32219.1 - 0.041 12.4 0.1 0.09 11.3 0.0 1.5 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein AAA_16 PF13191.6 CBY32219.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBY32219.1 - 0.058 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 CBY32219.1 - 0.061 12.6 0.1 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 CBY32219.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY32219.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CBY32219.1 - 0.16 11.3 0.0 0.37 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Utp8 PF10395.9 CBY32220.1 - 0.047 12.2 1.1 0.05 12.1 1.1 1.0 1 0 0 1 1 1 0 Utp8 family SVM_signal PF12113.8 CBY32220.1 - 0.28 11.1 2.9 0.5 10.3 2.9 1.4 1 0 0 1 1 1 0 SVM protein signal sequence EGF_CA PF07645.15 CBY32221.1 - 8.1e-13 48.3 68.6 6.4e-07 29.5 9.0 5.7 5 0 0 5 5 5 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY32221.1 - 4e-05 23.8 51.9 0.67 10.3 10.2 6.1 3 2 1 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY32221.1 - 0.00025 21.3 47.1 0.0011 19.2 4.9 5.7 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.7 CBY32221.1 - 0.00076 19.6 23.2 0.003 17.7 8.0 5.8 5 1 0 5 5 5 3 EGF domain cEGF PF12662.7 CBY32221.1 - 0.035 14.0 51.0 0.054 13.4 5.5 7.0 6 0 0 6 6 6 0 Complement Clr-like EGF-like MBG_2 PF18676.1 CBY32221.1 - 0.4 11.4 2.5 1.6 9.4 0.1 3.0 3 0 0 3 3 3 0 MBG domain (YGX type) TRP_2 PF08344.11 CBY32222.1 - 3e-22 78.6 1.5 6.2e-22 77.6 1.5 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CBY32222.1 - 1.3e-09 38.5 0.1 8.8e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY32222.1 - 6.8e-07 29.1 1.7 2 9.2 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 CBY32222.1 - 0.00047 20.7 0.0 0.045 14.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY32222.1 - 0.0065 16.9 0.1 0.42 11.1 0.1 3.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY32222.1 - 0.013 15.8 0.0 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Sulfotransfer_1 PF00685.27 CBY32223.1 - 1.3e-07 31.4 0.0 6.9e-07 29.0 0.0 2.2 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY32223.1 - 2.2e-07 31.5 0.0 4.2e-06 27.3 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family EGF PF00008.27 CBY32224.1 - 0.00046 20.4 50.3 0.024 15.0 6.1 4.9 4 0 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 CBY32224.1 - 0.0025 18.0 35.5 0.1 12.8 3.0 4.8 4 1 0 4 4 4 3 EGF domain hEGF PF12661.7 CBY32224.1 - 0.021 15.5 4.4 0.021 15.5 4.4 6.5 6 1 0 6 6 6 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY32224.1 - 0.032 14.4 12.5 0.032 14.4 12.5 5.2 3 2 2 5 5 5 0 Calcium-binding EGF domain YtxH PF12732.7 CBY32225.1 - 0.033 14.7 0.1 0.044 14.3 0.1 1.4 1 1 0 1 1 1 0 YtxH-like protein Ubiquitin_2 PF14560.6 CBY32226.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain MR_MLE_C PF13378.6 CBY32227.1 - 1.6e-39 135.8 0.0 2.8e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CBY32227.1 - 5.4e-07 29.8 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ribonucleas_3_2 PF11469.8 CBY32227.1 - 0.081 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 Ribonuclease III Spo7 PF03907.13 CBY32229.1 - 0.016 14.7 0.2 0.017 14.6 0.2 1.1 1 0 0 1 1 1 0 Spo7-like protein DUF3328 PF11807.8 CBY32229.1 - 0.089 12.6 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) ASH PF15780.5 CBY32230.1 - 2.8e-28 98.0 11.8 0.0015 18.7 0.0 13.0 13 0 0 13 13 13 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBY32230.1 - 3e-18 65.8 1.3 0.54 10.4 0.0 9.0 10 0 0 10 10 10 5 Flagellar-associated PapD-like DUF1573 PF07610.11 CBY32230.1 - 2.7e-14 53.0 11.2 1.7 8.8 0.1 13.8 16 1 0 16 16 16 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CBY32230.1 - 7.3e-12 45.1 7.2 0.00019 21.2 0.0 7.5 7 1 0 7 7 7 2 MSP (Major sperm protein) domain MYCBPAP PF14646.6 CBY32230.1 - 7.5e-12 44.9 0.9 0.13 11.2 0.0 6.3 6 0 0 6 6 6 4 MYCBP-associated protein family Hydin_ADK PF17213.3 CBY32230.1 - 1.8e-08 34.9 0.1 3.4e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain TMEM131_like PF12371.8 CBY32230.1 - 0.00062 20.0 12.5 13 6.1 0.0 8.1 10 0 0 10 10 10 1 Transmembrane protein 131-like SKI PF01202.22 CBY32230.1 - 0.007 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 CBY32230.1 - 0.019 15.5 0.1 0.49 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CBY32230.1 - 0.04 14.3 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain LBP_BPI_CETP_C PF02886.17 CBY32230.1 - 0.097 12.1 0.2 0.29 10.5 0.2 1.8 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Cytidylate_kin PF02224.18 CBY32230.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Tropomodulin PF03250.14 CBY32232.1 - 8.2e-48 162.0 4.4 1.9e-47 160.9 4.4 1.5 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 CBY32232.1 - 0.0034 17.3 2.8 0.032 14.3 0.1 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 CBY32232.1 - 2.8 8.5 8.0 1.3 9.6 0.4 3.1 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) PBC PF03792.13 CBY32233.1 - 2.1e-75 252.7 3.6 2.1e-75 252.7 3.6 1.5 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 CBY32233.1 - 6.2e-20 70.8 0.8 1.5e-19 69.5 0.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY32233.1 - 5.3e-16 58.2 0.0 1.6e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY32233.1 - 0.0015 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 CBY32233.1 - 0.012 15.6 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix RPN7 PF10602.9 CBY32233.1 - 0.055 13.2 0.6 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 26S proteasome subunit RPN7 HTH_26 PF13443.6 CBY32233.1 - 0.13 12.7 0.2 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 CBY32233.1 - 0.16 11.8 0.5 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Acetyltransf_1 PF00583.25 CBY32234.1 - 1.9e-21 76.5 0.1 2.4e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY32234.1 - 3.4e-13 49.8 0.0 4.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY32234.1 - 1.3e-12 47.7 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY32234.1 - 9.3e-09 35.2 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBY32234.1 - 1.7e-07 32.0 0.0 1.9e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY32234.1 - 2.1e-06 27.8 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBY32234.1 - 3.8e-06 26.6 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY32234.1 - 0.0054 16.8 0.0 0.0096 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 CBY32234.1 - 0.034 14.3 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-U PF06728.13 CBY32235.1 - 4.8e-07 29.2 1.4 7.1e-07 28.6 1.4 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Transgly_assoc PF04226.13 CBY32235.1 - 0.035 14.4 0.8 0.051 13.8 0.8 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein PIG-U PF06728.13 CBY32236.1 - 2.1e-21 76.4 21.5 1e-18 67.6 18.2 2.8 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U ZU5 PF00791.20 CBY32237.1 - 1.9e-21 76.3 0.2 3.4e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 ZU5 domain PHD PF00628.29 CBY32238.1 - 0.0016 18.3 14.6 0.0016 18.3 14.6 3.9 2 1 2 4 4 4 1 PHD-finger Spore_Cse60 PF10957.8 CBY32238.1 - 0.023 14.7 0.3 0.058 13.4 0.3 1.6 1 0 0 1 1 1 0 Sporulation protein Cse60 RNase_PH_C PF03725.15 CBY32238.1 - 0.094 12.8 0.5 0.49 10.5 0.2 2.3 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Ppx-GppA PF02541.16 CBY32238.1 - 0.1 12.0 0.5 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Nmad5 PF18757.1 CBY32239.1 - 0.00091 19.5 3.1 0.0013 19.0 3.1 1.3 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 REV PF00424.18 CBY32240.1 - 0.16 12.0 2.3 0.97 9.5 2.8 1.9 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) HEAT PF02985.22 CBY32241.1 - 2.1e-07 30.6 2.5 20 5.8 0.0 7.5 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CBY32241.1 - 0.00016 22.2 2.2 3.9 8.1 0.0 5.7 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region Herpes_heli_pri PF05774.11 CBY32241.1 - 0.012 15.9 0.2 0.038 14.2 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component Cohesin_HEAT PF12765.7 CBY32241.1 - 0.025 14.9 1.7 22 5.5 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 CBY32241.1 - 0.028 14.9 0.0 33 5.1 0.0 4.6 6 0 0 6 6 6 0 HEAT-like repeat Cnd1 PF12717.7 CBY32241.1 - 0.029 14.4 6.9 23 5.0 0.2 5.1 5 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ATP_synt_H PF05493.13 CBY32242.1 - 5.7e-20 71.6 9.7 6.9e-20 71.3 9.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H MRP-S22 PF10245.9 CBY32243.1 - 3.1e-28 99.2 0.1 6.3e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Metallophos PF00149.28 CBY32244.1 - 2.1e-35 123.1 0.9 3.3e-35 122.4 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY32244.1 - 0.019 15.4 0.1 0.046 14.2 0.1 1.7 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-TAZ PF02135.16 CBY32244.1 - 0.021 15.3 0.2 0.054 14.0 0.2 1.7 1 0 0 1 1 1 0 TAZ zinc finger Glyco_hydro_65N PF03636.15 CBY32244.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain EIF_2_alpha PF07541.12 CBY32245.1 - 1.1e-33 115.7 1.6 2.8e-33 114.5 0.4 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CBY32245.1 - 8.4e-11 42.1 0.1 1.6e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Mst1_SARAH PF11629.8 CBY32245.1 - 0.0088 16.1 0.0 0.037 14.1 0.0 2.1 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 AcetDehyd-dimer PF09290.11 CBY32245.1 - 0.012 15.8 0.2 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF4407 PF14362.6 CBY32245.1 - 0.054 12.9 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 CBY32246.1 - 1.6e-25 89.9 0.0 4.3e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY32246.1 - 7.1e-25 87.9 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY32246.1 - 0.00084 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase TPT PF03151.16 CBY32247.1 - 1.7e-18 67.0 16.4 2e-18 66.8 16.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CBY32247.1 - 6.9e-08 32.1 21.2 1e-07 31.5 21.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY32247.1 - 0.0015 18.7 30.1 0.049 13.8 15.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Ribosomal_L14 PF00238.19 CBY32248.1 - 7e-34 116.5 0.1 7.8e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ubiquitin PF00240.23 CBY32249.1 - 1.9e-34 117.2 0.4 2.6e-34 116.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBY32249.1 - 1.5e-30 104.9 14.2 2.2e-30 104.3 14.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBY32249.1 - 1.8e-16 59.7 0.5 2.6e-16 59.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBY32249.1 - 1.6e-05 25.3 0.1 6.5e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CBY32249.1 - 0.0027 18.0 0.1 0.0053 17.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBY32249.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBY32249.1 - 0.0047 17.0 0.1 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBY32249.1 - 0.014 15.4 1.2 4.2 7.5 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CBY32249.1 - 0.018 15.6 0.1 0.021 15.4 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Kelch_1 PF01344.25 CBY32250.1 - 3.6e-75 247.3 20.5 3.6e-15 55.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY32250.1 - 4.3e-37 125.2 4.8 1.3e-06 28.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BACK PF07707.15 CBY32250.1 - 7.2e-35 119.2 1.1 1e-34 118.7 0.1 1.8 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CBY32250.1 - 2.1e-27 95.5 3.8 3.7e-27 94.7 3.8 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CBY32250.1 - 3.2e-17 62.3 8.6 0.00094 19.1 0.1 6.2 4 1 2 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY32250.1 - 5.3e-16 58.5 7.0 0.0066 16.7 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY32250.1 - 5.9e-12 45.1 12.0 0.057 13.4 0.2 6.4 6 0 0 6 6 6 5 Kelch motif DUF3342 PF11822.8 CBY32250.1 - 8.9e-06 25.8 2.9 0.0004 20.5 1.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Kelch_5 PF13854.6 CBY32250.1 - 3.3e-05 23.8 7.0 0.7 10.0 0.1 5.2 5 0 0 5 5 5 1 Kelch motif Glu_cyclase_2 PF05096.12 CBY32250.1 - 0.065 12.7 0.0 1 8.8 0.0 2.5 1 1 2 3 3 3 0 Glutamine cyclotransferase Skp1_POZ PF03931.15 CBY32250.1 - 0.088 13.0 0.2 0.31 11.3 0.1 1.9 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF2963 PF11178.8 CBY32250.1 - 0.16 11.7 0.3 96 2.8 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2963) SRR1 PF07985.12 CBY32251.1 - 3.4e-06 27.0 0.0 6.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SRR1 DUF572 PF04502.13 CBY32252.1 - 8.4e-72 242.6 15.0 8.4e-72 242.6 15.0 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF572) Porphobil_deam PF01379.20 CBY32252.1 - 0.0035 16.9 1.0 0.006 16.1 1.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Lipoprotein_10 PF03202.13 CBY32252.1 - 2.9 8.4 10.0 0.05 14.0 1.9 2.2 2 1 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region zf-C2H2 PF00096.26 CBY32253.1 - 3.7e-21 74.3 44.6 5.9e-05 23.3 0.7 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY32253.1 - 9e-20 69.7 40.8 0.00055 20.6 0.8 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY32253.1 - 1.9e-09 37.6 33.6 0.0041 17.4 0.2 6.7 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY32253.1 - 4.6e-09 36.3 49.5 0.01 16.2 0.8 6.9 6 1 0 6 6 6 4 Zinc-finger double domain zf-Di19 PF05605.12 CBY32253.1 - 2.6e-08 34.0 26.6 8.9e-05 22.7 2.7 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY32253.1 - 9.9e-06 25.8 18.7 4.9 7.7 0.2 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY32253.1 - 0.00016 21.6 41.8 0.015 15.3 0.0 7.1 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY32253.1 - 0.0063 16.2 21.8 5.5 6.9 1.2 5.7 5 1 1 6 6 6 4 zinc-finger C2H2-type GAGA PF09237.11 CBY32253.1 - 0.0066 16.2 9.5 0.36 10.7 0.8 3.8 3 1 0 3 3 3 1 GAGA factor zf-H2C2_5 PF13909.6 CBY32253.1 - 0.017 14.8 45.4 0.13 12.0 0.6 7.0 6 1 0 6 6 6 0 C2H2-type zinc-finger domain zf-BED PF02892.15 CBY32253.1 - 0.082 12.9 35.3 0.79 9.8 2.4 5.5 3 1 2 5 5 5 0 BED zinc finger zf-RING_7 PF02591.15 CBY32253.1 - 0.11 12.7 7.1 0.82 9.9 0.3 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2HC_2 PF13913.6 CBY32253.1 - 0.18 11.7 0.4 0.18 11.7 0.4 6.3 7 0 0 7 7 7 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 CBY32253.1 - 1.1 8.9 21.6 11 5.7 0.1 6.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 CBY32253.1 - 2 8.5 22.5 0.33 11.0 0.4 4.4 1 1 3 4 4 3 0 zinc-ribbons Zn-ribbon_8 PF09723.10 CBY32253.1 - 5.9 7.1 27.8 2 8.6 0.8 4.8 2 2 2 4 4 3 0 Zinc ribbon domain DUF2256 PF10013.9 CBY32253.1 - 6.3 7.0 18.1 11 6.3 0.0 5.2 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_8 PF15909.5 CBY32253.1 - 6.4 7.1 21.4 3.2 8.1 3.1 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon TUDOR PF00567.24 CBY32255.1 - 8.9e-05 22.5 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Tudor domain zf-CCCH_4 PF18044.1 CBY32255.1 - 0.035 13.9 0.5 0.084 12.7 0.5 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY32255.1 - 0.041 13.9 0.5 0.041 13.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CBY32255.1 - 0.047 13.6 0.4 0.047 13.6 0.4 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM PF05172.13 CBY32256.1 - 8.1e-21 73.9 0.1 1.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY32256.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBY32256.1 - 0.009 15.8 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.13 CBY32256.1 - 3.6 6.8 10.2 4.1 6.6 2.2 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Guanylate_cyc_2 PF09778.9 CBY32257.1 - 0.061 12.7 0.2 0.092 12.1 0.2 1.2 1 0 0 1 1 1 0 Guanylylate cyclase Connexin PF00029.19 CBY32258.1 - 1.2e-73 247.8 0.1 3.3e-42 144.9 0.2 2.1 2 0 0 2 2 2 2 Connexin Ribosomal_L17 PF01196.19 CBY32259.1 - 0.071 14.0 0.1 0.13 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L17 TypeIII_RM_meth PF12564.8 CBY32260.1 - 0.082 13.0 0.1 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit SNARE PF05739.19 CBY32260.1 - 0.25 11.4 1.4 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 SNARE domain Pup PF05639.11 CBY32260.1 - 0.37 11.7 7.8 6.6 7.7 0.0 2.6 1 1 1 2 2 2 0 Pup-like protein Ribosomal_L17 PF01196.19 CBY32261.1 - 0.12 13.3 0.1 0.22 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L17 Trypsin PF00089.26 CBY32262.1 - 8.1e-134 444.3 20.1 4e-56 190.3 0.1 4.3 4 0 0 4 4 4 3 Trypsin EGF_CA PF07645.15 CBY32262.1 - 3.3e-16 59.2 24.5 3.7e-10 39.8 7.3 6.5 5 1 1 6 6 6 2 Calcium-binding EGF domain DUF1986 PF09342.11 CBY32262.1 - 4.8e-06 26.9 0.2 0.55 10.6 0.0 4.0 4 0 0 4 4 4 3 Domain of unknown function (DUF1986) EGF_3 PF12947.7 CBY32262.1 - 0.0006 19.9 29.7 0.039 14.1 8.4 4.5 3 0 0 3 3 3 2 EGF domain cEGF PF12662.7 CBY32262.1 - 0.0072 16.2 2.3 0.0072 16.2 2.3 5.5 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY32262.1 - 3.2 7.9 22.7 5.5 7.1 5.4 4.3 4 0 0 4 4 4 0 MSP1 EGF domain 1 Trypsin PF00089.26 CBY32265.1 - 7.1e-15 55.4 1.3 1.6e-14 54.3 0.3 1.8 2 0 0 2 2 2 1 Trypsin RCR PF12273.8 CBY32266.1 - 0.024 15.3 0.1 0.038 14.6 0.1 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PHR PF08005.12 CBY32267.1 - 2.6e-48 164.5 1.2 2.6e-48 164.5 1.2 1.5 2 0 0 2 2 2 1 PHR domain BTB PF00651.31 CBY32267.1 - 8.4e-26 90.4 0.4 3.5e-24 85.2 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 CBY32267.1 - 1.7e-10 40.9 0.1 3.3e-09 36.8 0.0 2.6 1 1 1 2 2 2 1 BTB And C-terminal Kelch DUF4082 PF13313.6 CBY32267.1 - 0.11 12.5 0.2 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) dsrm PF00035.26 CBY32268.1 - 9.2e-16 58.3 0.4 6e-07 30.1 0.0 3.8 2 1 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY32268.1 - 0.6 10.4 2.8 6 7.2 0.5 3.3 3 2 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 FAM91_C PF14648.6 CBY32268.1 - 2.2 7.0 10.1 4.3 6.1 0.2 2.3 2 0 0 2 2 2 0 FAM91 C-terminus Endonuclease_NS PF01223.23 CBY32269.1 - 1.1e-54 185.7 0.0 1.3e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DALR_1 PF05746.15 CBY32270.1 - 1.1e-09 38.4 0.2 2.4e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 DALR anticodon binding domain AAA PF00004.29 CBY32271.1 - 1.3e-15 58.0 0.3 4.4e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBY32271.1 - 3.4e-11 43.6 0.3 2e-10 41.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CBY32271.1 - 4.7e-10 40.1 0.0 3.1e-08 34.2 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 CBY32271.1 - 3.7e-06 26.8 0.1 0.00064 19.6 0.0 3.4 3 0 0 3 3 3 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 CBY32271.1 - 1.1e-05 25.4 0.0 5.1e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 CBY32271.1 - 0.0024 18.2 0.5 0.011 16.1 0.5 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CBY32271.1 - 0.0039 16.5 0.0 0.0099 15.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CBY32271.1 - 0.0063 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase NACHT PF05729.12 CBY32271.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 CBY32271.1 - 0.067 13.2 0.0 0.067 13.2 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CBY32271.1 - 0.088 13.2 0.2 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF728 PF05304.12 CBY32271.1 - 3.1 7.6 5.2 2 8.2 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF728) CK_II_beta PF01214.18 CBY32272.1 - 2.1e-73 246.1 0.1 2.4e-73 245.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RRM_1 PF00076.22 CBY32273.1 - 1.7e-09 37.4 1.6 2.4e-09 36.9 0.0 2.2 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32273.1 - 0.035 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif zf-C2H2 PF00096.26 CBY32274.1 - 3e-16 58.9 21.3 2.9e-06 27.4 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY32274.1 - 1.3e-11 44.3 9.6 1.4e-07 31.6 2.7 4.5 5 0 0 5 5 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY32274.1 - 6e-10 39.1 18.6 0.0016 19.1 2.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY32274.1 - 0.0017 18.6 3.0 0.73 10.2 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CBY32274.1 - 0.0022 18.6 6.5 0.3 11.8 0.1 3.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CBY32274.1 - 0.035 14.1 1.4 0.035 14.1 1.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CBY32274.1 - 0.23 11.9 6.0 2.3 8.7 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CBY32274.1 - 0.3 11.2 2.8 7.2 6.7 0.7 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CBY32274.1 - 0.51 10.1 18.9 0.054 13.3 2.8 3.8 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-TRAF PF02176.18 CBY32274.1 - 2.5 8.9 5.6 0.62 10.8 0.9 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_11 PF16622.5 CBY32274.1 - 2.9 7.7 9.8 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY32274.1 - 6.3 7.2 7.6 1.6 9.1 1.5 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CBY32274.1 - 8.2 7.0 7.3 22 5.6 2.0 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Homeodomain PF00046.29 CBY32275.1 - 2.7e-20 72.0 10.2 7.1e-20 70.6 10.2 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY32275.1 - 0.032 14.1 1.6 0.032 14.1 1.6 2.7 2 1 1 3 3 3 0 Homeobox KN domain Homez PF11569.8 CBY32275.1 - 0.15 11.6 0.2 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez TPR_21 PF09976.9 CBY32276.1 - 0.0036 17.0 0.3 0.0051 16.5 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain DUF4366 PF14283.6 CBY32276.1 - 0.012 15.6 1.3 0.05 13.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SWIRM-assoc_2 PF16496.5 CBY32276.1 - 0.11 11.4 4.5 0.14 11.0 4.5 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TMEM208_SND2 PF05620.11 CBY32276.1 - 1.1 9.0 5.8 0.54 10.0 0.3 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Phospholip_A2_1 PF00068.19 CBY32277.1 - 1.7e-07 31.7 4.9 2e-07 31.5 4.9 1.1 1 0 0 1 1 1 1 Phospholipase A2 EGF PF00008.27 CBY32278.1 - 8e-10 38.8 19.6 6e-06 26.4 6.6 4.1 4 0 0 4 4 4 2 EGF-like domain EGF_2 PF07974.13 CBY32278.1 - 0.013 15.9 3.7 0.013 15.9 3.7 3.6 3 1 0 3 3 3 0 EGF-like domain Trypsin PF00089.26 CBY32279.1 - 5.4e-101 337.0 0.0 9e-51 172.8 0.0 2.0 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.11 CBY32279.1 - 7.8e-07 29.5 0.0 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) DUF316 PF03761.15 CBY32279.1 - 1.5e-06 28.0 0.0 0.039 13.5 0.0 2.7 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 Frtz PF11768.8 CBY32279.1 - 0.0052 15.2 0.0 0.7 8.1 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Vezatin PF12632.7 CBY32279.1 - 0.2 11.0 0.0 9.9 5.4 0.0 2.1 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes VESA1_N PF12785.7 CBY32280.1 - 0.21 10.5 5.4 0.23 10.4 5.4 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 EF-hand_1 PF00036.32 CBY32281.1 - 3.1e-24 82.7 2.3 2.9e-07 29.5 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBY32281.1 - 5e-22 78.1 0.1 5.6e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY32281.1 - 5.3e-21 72.7 0.2 8e-06 25.4 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CBY32281.1 - 1.3e-17 62.4 3.9 1.6e-06 27.3 0.2 3.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY32281.1 - 8e-14 51.2 6.3 0.00048 19.9 0.3 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY32281.1 - 7.7e-06 25.8 0.0 0.023 14.7 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY32281.1 - 0.0045 17.3 0.0 0.46 10.8 0.0 2.9 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY32281.1 - 0.0099 15.8 0.8 3.2 7.6 0.0 3.4 2 1 2 4 4 4 1 Caleosin related protein EF-hand_9 PF14658.6 CBY32281.1 - 0.012 15.9 0.0 0.067 13.5 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CBY32281.1 - 0.035 14.3 0.1 7.5 6.8 0.0 2.6 2 1 1 3 3 3 0 Dockerin type I domain TcdB_toxin_midN PF12256.8 CBY32281.1 - 0.068 12.5 0.0 5.9 6.2 0.0 2.2 1 1 1 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region Homez PF11569.8 CBY32281.1 - 0.081 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez BRE1 PF08647.11 CBY32282.1 - 0.26 11.4 8.6 0.36 10.9 8.6 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase EGF_CA PF07645.15 CBY32284.1 - 9.7e-114 371.4 255.0 2.7e-10 40.3 12.7 16.0 15 1 1 16 16 16 14 Calcium-binding EGF domain EGF_3 PF12947.7 CBY32284.1 - 1.3e-71 236.5 218.2 6.1e-09 35.9 7.4 15.7 13 1 1 15 15 15 14 EGF domain cEGF PF12662.7 CBY32284.1 - 1.5e-62 207.0 154.5 1.4e-06 28.1 5.0 15.8 15 0 0 15 15 15 14 Complement Clr-like EGF-like EGF PF00008.27 CBY32284.1 - 9.4e-38 128.1 184.7 1.4e-05 25.2 6.2 16.3 15 1 0 15 15 15 14 EGF-like domain hEGF PF12661.7 CBY32284.1 - 8.2e-27 92.9 157.4 0.00043 20.8 6.9 16.5 15 0 0 15 15 15 14 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY32284.1 - 2.4e-20 72.5 197.8 0.013 15.8 0.9 16.3 11 3 4 15 15 15 13 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY32284.1 - 0.00095 19.2 184.4 0.0051 16.8 4.9 15.5 15 0 0 15 15 15 8 MSP1 EGF domain 1 EGF_2 PF07974.13 CBY32284.1 - 0.004 17.5 9.3 0.004 17.5 9.3 15.8 14 1 1 15 15 15 6 EGF-like domain DUF3439 PF11921.8 CBY32284.1 - 0.0057 16.6 2.4 0.0057 16.6 2.4 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3439) Plasmod_Pvs28 PF06247.11 CBY32284.1 - 0.017 15.4 187.8 0.072 13.4 7.0 16.2 12 4 3 16 16 16 0 Pvs28 EGF domain IL2 PF00715.17 CBY32286.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 SNAPc_SNAP43 PF09808.9 CBY32287.1 - 2.5e-20 73.3 2.1 2.7e-20 73.1 2.1 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Herpes_IE68 PF02479.16 CBY32287.1 - 0.093 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus immediate early protein Pkinase_Tyr PF07714.17 CBY32289.1 - 4.5e-61 206.4 0.0 7.7e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY32289.1 - 2.2e-29 102.6 0.0 3.6e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ephrin_lbd PF01404.19 CBY32289.1 - 1.1e-27 97.3 0.1 2e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain fn3 PF00041.21 CBY32289.1 - 2.6e-18 66.2 0.5 5.1e-09 36.4 0.0 2.9 3 0 0 3 3 3 2 Fibronectin type III domain SAM_2 PF07647.17 CBY32289.1 - 2.7e-11 43.4 0.0 2.7e-10 40.2 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY32289.1 - 4.6e-09 36.6 0.0 1.2e-08 35.3 0.0 1.7 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) Ephrin_rec_like PF07699.13 CBY32289.1 - 6.6e-06 25.8 8.0 6.6e-06 25.8 8.0 2.5 1 1 1 2 2 2 1 Putative ephrin-receptor like SAM_KSR1 PF13543.6 CBY32289.1 - 0.048 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Pur_ac_phosph_N PF16656.5 CBY32289.1 - 0.071 13.7 0.1 11 6.6 0.0 2.9 1 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain cEGF PF12662.7 CBY32289.1 - 1 9.4 7.1 7.9 6.5 0.4 2.9 2 0 0 2 2 2 0 Complement Clr-like EGF-like Zn_clus PF00172.18 CBY32289.1 - 3.8 7.7 7.3 1.6 9.0 3.1 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_L_D3 PF02787.19 CBY32291.1 - 0.54 10.6 4.5 0.73 10.2 1.7 2.6 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Tubulin PF00091.25 CBY32292.1 - 4e-68 229.5 0.0 5.4e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY32292.1 - 2.8e-52 176.2 0.0 4.4e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY32292.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain CUB PF00431.20 CBY32293.1 - 4.9e-17 62.3 0.4 7.8e-17 61.6 0.4 1.3 1 0 0 1 1 1 1 CUB domain DUF3671 PF12420.8 CBY32293.1 - 0.027 14.5 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function CUB_2 PF02408.20 CBY32293.1 - 0.047 13.5 0.2 0.09 12.5 0.2 1.5 1 0 0 1 1 1 0 CUB-like domain DUF4366 PF14283.6 CBY32293.1 - 0.2 11.7 2.0 8.7 6.4 0.6 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4366) CIA30 PF08547.12 CBY32294.1 - 4.1e-26 91.9 0.0 5.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 CBY32294.1 - 0.0014 18.5 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) SGBP_B_XBD PF18329.1 CBY32294.1 - 0.0026 17.8 0.0 0.0084 16.1 0.0 1.7 1 1 0 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain Lipocalin_4 PF13648.6 CBY32295.1 - 0.065 14.2 0.2 0.18 12.8 0.2 1.8 1 0 0 1 1 1 0 Lipocalin-like domain LapA_dom PF06305.11 CBY32295.1 - 0.16 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UQ_con PF00179.26 CBY32296.1 - 9.7e-07 28.5 0.2 1.8e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme CIA30 PF08547.12 CBY32297.1 - 1.9e-26 93.0 0.0 2.3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 CBY32297.1 - 0.00026 20.9 0.0 0.00033 20.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) SGBP_B_XBD PF18329.1 CBY32297.1 - 0.0013 18.7 0.1 0.0028 17.6 0.1 1.7 1 1 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain DHHC PF01529.20 CBY32299.1 - 2.1e-31 108.8 1.0 2.1e-31 108.8 1.0 2.6 3 0 0 3 3 3 1 DHHC palmitoyltransferase PHO4 PF01384.20 CBY32299.1 - 0.19 10.8 2.1 1.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Phosphate transporter family DUF1272 PF06906.11 CBY32299.1 - 0.6 10.2 8.5 0.069 13.3 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HXXEE PF13787.6 CBY32299.1 - 3 8.7 8.1 2.3 9.1 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Topoisom_bac PF01131.20 CBY32300.1 - 1.2e-112 377.0 0.0 1.5e-112 376.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBY32300.1 - 1.7e-17 63.5 0.0 3.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain BTB_2 PF02214.22 CBY32302.1 - 9.2e-19 67.6 0.2 8.9e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Laminin_G_2 PF02210.24 CBY32303.1 - 2.1e-30 105.9 1.8 2.2e-07 31.5 0.0 6.1 5 2 0 5 5 5 4 Laminin G domain Laminin_G_1 PF00054.23 CBY32303.1 - 2.5e-16 60.1 0.2 0.0024 18.1 0.0 6.3 6 0 0 6 6 6 3 Laminin G domain SKA2 PF16740.5 CBY32303.1 - 0.035 13.9 1.8 0.12 12.1 1.8 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 PMC2NT PF08066.12 CBY32303.1 - 0.51 11.1 4.1 0.39 11.4 1.7 2.1 2 0 0 2 2 2 0 PMC2NT (NUC016) domain HrpB2 PF09487.10 CBY32303.1 - 1.3 9.5 6.8 9.9 6.6 0.3 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF4775 PF16001.5 CBY32303.1 - 1.7 7.9 5.6 3.2 7.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) TMPIT PF07851.13 CBY32303.1 - 2 7.6 5.5 4.1 6.6 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein PLC-beta_C PF08703.10 CBY32303.1 - 2.3 8.1 9.4 4.5 7.2 7.4 2.3 2 0 0 2 2 2 0 PLC-beta C terminal DUF948 PF06103.11 CBY32303.1 - 2.8 8.3 14.3 2.1 8.7 0.5 4.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PIN_8 PF18476.1 CBY32303.1 - 2.8 7.7 9.5 0.71 9.7 4.9 2.2 1 1 2 3 3 3 0 PIN like domain Laminin_EGF PF00053.24 CBY32304.1 - 6.1e-136 442.5 435.7 6.1e-11 42.3 15.6 23.4 18 3 5 23 23 23 22 Laminin EGF domain Laminin_N PF00055.17 CBY32304.1 - 3.7e-71 239.4 0.0 3.7e-71 239.4 0.0 4.6 3 1 1 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_B PF00052.18 CBY32304.1 - 6.7e-20 71.4 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Laminin B (Domain IV) F5_F8_type_C PF00754.25 CBY32304.1 - 0.00041 20.5 0.1 0.00086 19.4 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Glycophorin_A PF01102.18 CBY32305.1 - 0.0014 18.9 0.0 0.0064 16.7 0.0 2.1 1 0 0 1 1 1 1 Glycophorin A NPR3 PF03666.13 CBY32305.1 - 0.0043 15.9 0.2 0.0043 15.9 0.2 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 CbiG_mid PF11761.8 CBY32305.1 - 0.09 12.9 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis central region B12D PF06522.11 CBY32305.1 - 0.17 11.7 1.9 0.26 11.1 0.0 2.3 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Syndecan PF01034.20 CBY32305.1 - 0.22 11.5 0.6 0.55 10.2 0.6 1.7 1 0 0 1 1 1 0 Syndecan domain Ctr PF04145.15 CBY32305.1 - 0.36 11.4 0.9 6.5 7.4 0.8 2.2 1 1 0 1 1 1 0 Ctr copper transporter family EELM2 PF15863.5 CBY32306.1 - 0.37 10.9 5.1 10 6.2 0.4 3.0 3 0 0 3 3 3 0 Extended EGL-27 and MTA1 homology domain VPS28 PF03997.12 CBY32306.1 - 0.44 10.2 6.8 0.074 12.7 1.5 2.4 2 1 0 3 3 3 0 VPS28 protein Fez1 PF06818.15 CBY32306.1 - 0.49 10.8 22.0 2.5 8.5 9.6 3.1 3 0 0 3 3 3 0 Fez1 FapA PF03961.13 CBY32306.1 - 2.6 6.6 17.8 3 6.4 4.6 2.8 2 1 1 3 3 3 0 Flagellar Assembly Protein A HeLo PF14479.6 CBY32306.1 - 8.3 6.2 14.6 9.3 6.0 12.4 2.3 2 1 0 2 2 2 0 Prion-inhibition and propagation ABC_tran_CTD PF16326.5 CBY32306.1 - 8.4 6.7 19.6 3.9 7.8 0.7 4.4 3 1 1 4 4 4 0 ABC transporter C-terminal domain CAP PF00188.26 CBY32308.1 - 5.1e-15 56.4 0.1 8.7e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.19 CBY32309.1 - 1.8e-07 31.3 48.9 7.5e-05 22.9 9.5 4.3 4 0 0 4 4 4 3 Thrombospondin type 1 domain Adeno_PV PF03910.13 CBY32309.1 - 0.87 8.2 7.1 1.3 7.7 7.1 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Pkinase PF00069.25 CBY32310.1 - 1.2e-55 188.7 0.0 1.2e-55 188.7 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32310.1 - 5.5e-44 150.4 0.1 1.2e-43 149.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase OSR1_C PF12202.8 CBY32310.1 - 1.2e-06 28.6 0.1 5.3e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Kdo PF06293.14 CBY32310.1 - 0.0016 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY32310.1 - 0.0066 15.3 6.6 0.017 13.9 0.0 3.0 2 1 1 3 3 3 1 Fungal protein kinase APH PF01636.23 CBY32310.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Spt5_N PF11942.8 CBY32311.1 - 0.014 16.3 4.0 0.016 16.1 4.0 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MANEC PF07502.14 CBY32312.1 - 1.7e-15 57.1 4.2 3.6e-15 56.0 4.2 1.6 1 0 0 1 1 1 1 MANEC domain Ldl_recept_a PF00057.18 CBY32312.1 - 9.2e-08 32.2 9.0 9.2e-08 32.2 9.0 2.4 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A TMEM154 PF15102.6 CBY32312.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family PAN_4 PF14295.6 CBY32312.1 - 0.022 14.7 1.4 0.022 14.7 1.4 2.3 2 0 0 2 2 2 0 PAN domain DUF3377 PF11857.8 CBY32312.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FAM176 PF14851.6 CBY32312.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Topoisom_bac PF01131.20 CBY32313.1 - 1.9e-112 376.3 0.0 2.5e-112 375.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBY32313.1 - 1.7e-17 63.5 0.0 3.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain BTB_2 PF02214.22 CBY32316.1 - 2.7e-18 66.1 0.2 9.4e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Laminin_EGF PF00053.24 CBY32317.1 - 1.6e-110 361.1 381.9 6.5e-11 42.2 15.6 20.6 16 4 4 20 20 20 17 Laminin EGF domain Laminin_N PF00055.17 CBY32317.1 - 6e-71 238.8 0.0 6e-71 238.8 0.0 3.7 2 1 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_G_2 PF02210.24 CBY32317.1 - 2.5e-18 66.8 1.0 3.9e-07 30.7 0.0 4.8 5 0 0 5 5 5 3 Laminin G domain Laminin_B PF00052.18 CBY32317.1 - 3.5e-17 62.5 0.1 2.1e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Laminin B (Domain IV) Laminin_G_1 PF00054.23 CBY32317.1 - 1.6e-12 47.8 0.1 0.0069 16.6 0.0 5.0 5 0 0 5 5 5 3 Laminin G domain F5_F8_type_C PF00754.25 CBY32317.1 - 0.00044 20.4 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain DUF3713 PF12506.8 CBY32317.1 - 0.14 12.5 2.6 0.63 10.4 2.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) SKA2 PF16740.5 CBY32317.1 - 0.36 10.6 4.9 0.38 10.6 1.7 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Glycophorin_A PF01102.18 CBY32318.1 - 0.0013 18.9 0.4 0.0061 16.8 0.0 2.2 2 0 0 2 2 2 1 Glycophorin A NPR3 PF03666.13 CBY32318.1 - 0.0031 16.4 4.8 0.0047 15.8 0.2 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 C1_2 PF03107.16 CBY32318.1 - 0.0072 16.6 11.0 0.013 15.8 1.4 2.7 2 0 0 2 2 2 1 C1 domain B12D PF06522.11 CBY32318.1 - 0.038 13.8 0.0 0.2 11.5 0.0 2.2 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Syndecan PF01034.20 CBY32318.1 - 0.25 11.3 0.6 0.54 10.2 0.6 1.6 1 0 0 1 1 1 0 Syndecan domain Ctr PF04145.15 CBY32318.1 - 0.32 11.6 2.4 14 6.3 2.3 2.2 1 1 0 1 1 1 0 Ctr copper transporter family CC2-LZ PF16516.5 CBY32319.1 - 0.022 15.1 3.9 0.022 15.1 3.9 3.5 3 1 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator EELM2 PF15863.5 CBY32319.1 - 0.57 10.3 6.0 9.5 6.3 0.6 2.9 3 0 0 3 3 3 0 Extended EGL-27 and MTA1 homology domain HeLo PF14479.6 CBY32319.1 - 2.5 7.9 13.7 11 5.8 13.7 2.1 1 1 0 1 1 1 0 Prion-inhibition and propagation DUF948 PF06103.11 CBY32319.1 - 3 8.2 7.9 3.7 7.9 0.2 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 CBY32319.1 - 4.3 7.7 22.1 8.5 6.8 12.2 2.4 2 1 0 2 2 2 0 Fez1 DUF1729 PF08354.10 CBY32319.1 - 4.8 6.0 10.2 0.26 10.1 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) DUF3439 PF11921.8 CBY32320.1 - 0.18 11.7 4.7 0.37 10.8 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 CBY32320.1 - 0.34 9.0 2.1 0.45 8.5 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TSP_1 PF00090.19 CBY32321.1 - 7e-16 58.2 73.8 8.8e-11 41.9 9.3 5.5 6 0 0 6 6 6 4 Thrombospondin type 1 domain CAP PF00188.26 CBY32321.1 - 3.2e-14 53.8 0.1 7.4e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GREB1 PF15782.5 CBY32321.1 - 1.9 5.5 4.1 2.5 5.1 4.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 CBY32322.1 - 2.5e-19 69.7 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32322.1 - 0.00011 21.5 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Nucleocap_ssRNA PF11128.8 CBY32322.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid AbiJ_NTD3 PF18860.1 CBY32322.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 PIP5K PF01504.18 CBY32323.1 - 4.2e-84 282.0 0.2 6e-84 281.5 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_M2 PF01401.18 CBY32325.1 - 2.2e-33 115.7 0.0 2.5e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme sCache_2 PF17200.4 CBY32325.1 - 0.21 11.4 0.1 0.54 10.1 0.1 1.7 2 0 0 2 2 2 0 Single Cache domain 2 Zip PF02535.22 CBY32326.1 - 5.7e-17 61.9 0.3 7.3e-17 61.6 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CBY32327.1 - 1.1e-14 54.4 0.6 1.2e-14 54.3 0.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CREPT PF16566.5 CBY32328.1 - 0.039 14.1 3.4 0.079 13.1 3.4 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 CBY32328.1 - 0.04 14.2 2.0 0.04 14.2 2.0 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein GreA_GreB_N PF03449.15 CBY32328.1 - 0.19 11.9 5.2 0.1 12.7 2.4 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Exonuc_VII_L PF02601.15 CBY32328.1 - 1.2 8.7 4.1 2 7.9 4.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBY32328.1 - 2.8 8.0 17.2 67 3.5 17.2 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FtsX_ECD PF18075.1 CBY32328.1 - 7.1 7.3 8.2 69 4.2 5.6 3.1 2 1 1 3 3 3 0 FtsX extracellular domain Occludin_ELL PF07303.13 CBY32328.1 - 7.2 7.4 14.0 1.3 9.8 2.3 3.3 2 1 2 4 4 4 0 Occludin homology domain Pkinase PF00069.25 CBY32329.1 - 1.5e-41 142.5 0.0 1.8e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32329.1 - 6.4e-14 51.8 0.0 8.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY32329.1 - 8.1e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY32329.1 - 9.3e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY32329.1 - 1.3e-05 24.2 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY32329.1 - 0.00096 19.1 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY32329.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CBY32329.1 - 0.033 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PilN_bio_d PF18222.1 CBY32329.1 - 0.16 12.3 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain Piwi PF02171.17 CBY32330.1 - 1.2e-103 346.6 0.9 1.6e-103 346.1 0.9 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY32330.1 - 1.2e-20 74.5 0.0 2.9e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY32330.1 - 6.4e-18 64.9 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY32330.1 - 5.6e-15 54.7 0.0 1.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY32330.1 - 9e-12 45.1 0.0 2.7e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CBY32330.1 - 7.3e-05 22.9 0.1 0.0008 19.6 0.0 2.9 2 0 0 2 2 2 1 Mid domain of argonaute ubiquitin PF00240.23 CBY32331.1 - 3.6e-05 23.4 0.0 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Herpes_LMP1 PF05297.11 CBY32331.1 - 0.78 8.9 7.0 1.1 8.3 7.0 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PhoPQ_related PF10142.9 CBY32332.1 - 3.5e-89 299.0 0.4 4.5e-89 298.7 0.4 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Med18 PF09637.10 CBY32333.1 - 2.4e-25 89.8 0.0 3.3e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Med18 protein PDZ PF00595.24 CBY32334.1 - 8.3e-72 237.6 29.3 2.7e-15 56.5 0.9 6.3 6 0 0 6 6 6 6 PDZ domain PDZ_6 PF17820.1 CBY32334.1 - 2.7e-37 126.4 21.7 1.2e-09 37.8 0.3 6.7 7 0 0 7 7 7 5 PDZ domain PDZ_2 PF13180.6 CBY32334.1 - 4.5e-27 94.2 16.1 1.7e-07 31.4 0.1 6.4 5 1 1 6 6 6 6 PDZ domain Tricorn_PDZ PF14685.6 CBY32334.1 - 7.8e-05 22.6 5.5 0.6 10.1 0.1 5.1 5 0 0 5 5 5 2 Tricorn protease PDZ domain PDZ PF00595.24 CBY32335.1 - 1.9e-133 435.1 51.5 1.3e-15 57.5 0.1 13.5 13 0 0 13 13 13 13 PDZ domain PDZ_6 PF17820.1 CBY32335.1 - 6e-99 323.8 31.0 2.6e-10 40.0 0.1 13.4 13 0 0 13 13 13 13 PDZ domain PDZ_2 PF13180.6 CBY32335.1 - 8.4e-79 260.0 35.7 2e-07 31.2 0.1 13.5 13 0 0 13 13 13 13 PDZ domain Tricorn_PDZ PF14685.6 CBY32335.1 - 5.3e-06 26.3 17.4 0.9 9.6 0.1 10.2 12 0 0 12 12 12 1 Tricorn protease PDZ domain PilN PF05137.13 CBY32335.1 - 0.0025 17.9 0.7 6.1 7.1 0.0 4.1 3 0 0 3 3 3 1 Fimbrial assembly protein (PilN) DUF3394 PF11874.8 CBY32335.1 - 0.011 15.4 10.1 1.2 8.7 0.0 6.4 6 1 0 7 7 7 0 Domain of unknown function (DUF3394) DUF4061 PF13270.6 CBY32336.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) 5-FTHF_cyc-lig PF01812.20 CBY32337.1 - 6.4e-22 78.3 0.0 9.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Lipase_3 PF01764.25 CBY32338.1 - 5.9e-23 81.3 0.0 9e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY32338.1 - 0.099 13.2 0.2 0.95 10.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CBY32338.1 - 0.12 11.9 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Ras PF00071.22 CBY32339.1 - 5.8e-22 78.0 0.0 6.1e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBY32339.1 - 0.00051 20.2 0.0 0.03 14.5 0.0 2.7 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY32339.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 CBY32339.1 - 0.13 11.7 0.0 0.58 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Ion_trans PF00520.31 CBY32340.1 - 1.2e-23 83.7 8.9 1.7e-23 83.1 8.9 1.2 1 0 0 1 1 1 1 Ion transport protein KCNQ_channel PF03520.14 CBY32340.1 - 1.4e-14 54.4 0.8 5.9e-14 52.3 0.7 1.9 2 0 0 2 2 2 1 KCNQ voltage-gated potassium channel Ion_trans_2 PF07885.16 CBY32340.1 - 8.1e-12 44.9 7.9 8.1e-12 44.9 7.9 2.4 3 0 0 3 3 3 1 Ion channel DUF4231 PF14015.6 CBY32340.1 - 0.0049 17.3 0.2 0.87 10.1 0.2 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) SpoIIM PF01944.17 CBY32340.1 - 0.091 12.8 5.0 0.061 13.4 2.4 2.0 1 1 1 2 2 2 0 Stage II sporulation protein M CD225 PF04505.12 CBY32340.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Interferon-induced transmembrane protein BNR_3 PF13859.6 CBY32341.1 - 0.049 12.9 0.0 0.052 12.8 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain RGCC PF15151.6 CBY32342.1 - 0.011 15.9 3.5 0.017 15.4 3.5 1.3 1 1 0 1 1 1 0 Response gene to complement 32 protein family LAP1C PF05609.12 CBY32342.1 - 0.096 11.8 2.7 0.098 11.7 2.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SR-25 PF10500.9 CBY32343.1 - 0.13 11.9 7.5 0.15 11.6 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ICAT PF06384.11 CBY32343.1 - 0.6 10.4 3.6 0.67 10.2 0.5 2.6 2 1 1 3 3 3 0 Beta-catenin-interacting protein ICAT Sulfotransfer_2 PF03567.14 CBY32344.1 - 5.1e-11 43.0 0.2 2.1e-10 40.9 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family IMUP PF15761.5 CBY32345.1 - 2 9.2 14.1 0.059 14.1 5.5 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein Golgin_A5 PF09787.9 CBY32345.1 - 3.6 7.0 22.7 12 5.3 16.6 2.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 PP2C PF00481.21 CBY32347.1 - 3.1e-44 151.5 0.0 3.8e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY32347.1 - 4.2e-08 33.1 0.0 7.7e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C UCH PF00443.29 CBY32347.1 - 0.054 13.0 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PEHE PF15275.6 CBY32348.1 - 0.01 16.4 1.0 0.01 16.4 1.0 4.7 3 2 2 5 5 5 0 PEHE domain Mito_carr PF00153.27 CBY32349.1 - 2.8e-43 145.8 2.8 4.5e-14 52.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0016 PF01169.19 CBY32351.1 - 8.2e-39 131.8 23.1 2.4e-20 72.6 9.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 CBY32351.1 - 1.5e-05 24.8 6.0 0.00022 21.0 0.1 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 CBY32351.1 - 0.033 13.9 8.6 0.051 13.3 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family Phage_holin_3_6 PF07332.11 CBY32351.1 - 0.063 13.3 0.1 0.063 13.3 0.1 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MMU163 PF17119.5 CBY32351.1 - 0.078 12.1 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CytochromB561_N PF09786.9 CBY32351.1 - 0.09 11.8 0.5 0.15 11.0 0.2 1.4 1 1 1 2 2 2 0 Cytochrome B561, N terminal FixQ PF05545.11 CBY32351.1 - 0.094 12.7 0.3 0.094 12.7 0.3 2.9 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.6 CBY32351.1 - 0.33 10.6 1.9 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_U4 PF03419.13 CBY32351.1 - 4 6.7 8.9 0.099 11.9 0.4 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Pyr_redox_2 PF07992.14 CBY32352.1 - 1.2e-65 221.7 8.9 2.4e-65 220.7 5.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBY32352.1 - 5.3e-41 139.3 2.0 5.3e-41 139.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBY32352.1 - 2.8e-20 72.6 7.9 1.2e-18 67.5 1.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBY32352.1 - 5.3e-09 35.9 0.3 5.3e-09 35.9 0.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY32352.1 - 1.6e-07 30.9 5.3 0.00064 19.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY32352.1 - 9.4e-07 28.2 0.3 9.4e-07 28.2 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBY32352.1 - 1.5e-06 28.3 4.8 3e-05 24.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY32352.1 - 2.7e-06 26.7 0.9 2.7e-06 26.7 0.9 2.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CBY32352.1 - 3.8e-06 25.9 10.9 0.002 16.9 0.9 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 CBY32352.1 - 4.9e-06 26.4 10.2 0.0043 16.7 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CBY32352.1 - 0.00013 21.3 0.5 0.068 12.3 0.1 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 CBY32352.1 - 0.00016 20.4 1.0 0.00033 19.4 0.3 1.7 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 CBY32352.1 - 0.0023 17.2 6.1 0.26 10.6 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBY32352.1 - 0.0028 17.0 2.3 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBY32352.1 - 0.019 14.2 11.4 0.15 11.3 0.5 3.5 4 0 0 4 4 4 0 FAD binding domain Amino_oxidase PF01593.24 CBY32352.1 - 0.18 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 CBY32352.1 - 0.51 9.9 5.3 9.2 5.8 0.2 3.6 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 CBY32352.1 - 3.5 6.6 5.8 2.4 7.1 0.4 2.8 3 1 1 4 4 4 0 Lycopene cyclase protein LEM PF03020.15 CBY32353.1 - 1.2e-09 37.6 1.3 1.1e-05 24.9 0.0 2.6 3 0 0 3 3 3 2 LEM domain LRR_8 PF13855.6 CBY32354.1 - 6.6e-13 48.2 5.0 7.3e-06 25.7 0.8 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBY32354.1 - 9.3e-11 41.8 4.5 7.5e-06 26.2 0.3 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY32354.1 - 1.1e-05 25.3 8.0 1.7 9.5 0.0 4.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 CBY32354.1 - 0.0039 17.1 2.7 14 6.1 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat DUF2615 PF11027.8 CBY32354.1 - 0.12 12.5 0.5 0.72 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) EMC3_TMCO1 PF01956.16 CBY32354.1 - 0.27 11.0 1.2 0.43 10.3 1.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Atrophin-1 PF03154.15 CBY32354.1 - 6.2 5.0 5.5 7.8 4.6 5.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family LPAM_1 PF08139.12 CBY32354.1 - 6.5 7.5 7.0 12 6.6 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CUB PF00431.20 CBY32356.1 - 0.00046 20.5 0.1 0.00084 19.6 0.1 1.4 1 0 0 1 1 1 1 CUB domain La PF05383.17 CBY32358.1 - 5.7e-11 42.3 0.0 1.5e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY32358.1 - 0.00029 20.6 0.1 0.3 10.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 CBY32358.1 - 0.012 15.6 0.1 0.036 14.1 0.1 1.8 1 0 0 1 1 1 0 SUZ-C motif MscS_porin PF12795.7 CBY32358.1 - 2.3 7.7 20.4 0.46 10.0 16.9 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Phospholip_A2_1 PF00068.19 CBY32360.1 - 1.7e-10 41.3 4.7 3.2e-10 40.4 4.7 1.4 1 0 0 1 1 1 1 Phospholipase A2 Neur_chan_LBD PF02931.23 CBY32361.1 - 3.5e-31 108.3 0.1 5.1e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain I-set PF07679.16 CBY32362.1 - 8.5e-80 262.9 0.3 4.4e-17 61.9 0.0 8.3 8 1 0 8 8 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY32362.1 - 8.1e-50 167.3 0.1 2.5e-13 50.4 0.0 7.6 7 0 0 7 7 7 7 Immunoglobulin domain fn3 PF00041.21 CBY32362.1 - 4.9e-34 116.5 0.0 2.5e-11 43.8 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 CBY32362.1 - 1.9e-25 88.8 0.8 5.9e-08 32.8 0.0 7.6 7 1 0 7 7 7 5 Immunoglobulin domain V-set PF07686.17 CBY32362.1 - 5.4e-23 81.3 0.0 0.00046 20.3 0.0 7.4 7 1 1 8 8 8 4 Immunoglobulin V-set domain Ig_2 PF13895.6 CBY32362.1 - 1.5e-21 76.5 0.2 5.2e-09 36.3 0.0 7.4 7 1 0 7 7 6 4 Immunoglobulin domain THB PF18362.1 CBY32362.1 - 4e-13 48.7 2.4 1.5e-12 46.9 0.1 2.4 2 0 0 2 2 2 1 Tri-helix bundle domain Pur_ac_phosph_N PF16656.5 CBY32362.1 - 5.2e-05 23.7 0.0 0.74 10.4 0.0 3.9 3 0 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CBY32362.1 - 0.0014 18.2 0.0 0.36 10.4 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.8 CBY32362.1 - 0.0016 18.6 0.0 0.35 11.1 0.0 3.9 4 0 0 4 4 3 1 Natural killer cell receptor 2B4 C2-set_2 PF08205.12 CBY32362.1 - 0.0082 16.2 1.8 12 6.0 0.0 4.3 5 0 0 5 5 5 0 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 CBY32362.1 - 0.0089 16.2 0.0 2.7 8.2 0.0 2.9 2 0 0 2 2 2 1 Fibronectin type III domain Izumo-Ig PF16706.5 CBY32362.1 - 0.015 15.4 0.3 2.4 8.3 0.0 4.2 5 0 0 5 5 5 0 Izumo-like Immunoglobulin domain Herpes_gI PF01688.17 CBY32362.1 - 0.069 13.1 0.2 43 4.0 0.0 4.1 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I MG2 PF01835.19 CBY32362.1 - 0.073 13.5 0.0 16 6.0 0.0 4.1 4 0 0 4 4 4 0 MG2 domain Glyco_transf_41 PF13844.6 CBY32363.1 - 1.9e-232 771.8 0.1 1.1e-231 769.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 41 TPR_1 PF00515.28 CBY32363.1 - 4e-89 289.1 29.8 2.7e-09 36.4 0.1 13.7 15 0 0 15 15 14 11 Tetratricopeptide repeat TPR_11 PF13414.6 CBY32363.1 - 4.3e-76 250.4 34.9 1.4e-11 43.9 0.6 14.6 8 4 8 16 16 14 11 TPR repeat TPR_8 PF13181.6 CBY32363.1 - 4.1e-60 195.0 15.3 7.5e-06 25.8 0.1 13.9 14 0 0 14 14 13 10 Tetratricopeptide repeat TPR_2 PF07719.17 CBY32363.1 - 1e-59 193.9 28.9 4.6e-06 26.3 0.0 14.0 15 0 0 15 15 13 11 Tetratricopeptide repeat TPR_17 PF13431.6 CBY32363.1 - 9.3e-55 179.2 32.2 1.2e-05 25.3 0.1 13.9 15 0 0 15 15 13 9 Tetratricopeptide repeat TPR_7 PF13176.6 CBY32363.1 - 2e-47 155.7 16.8 8.3e-05 22.3 0.0 12.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_12 PF13424.6 CBY32363.1 - 1.7e-43 146.8 31.7 3.4e-10 40.1 0.8 9.5 5 4 4 9 9 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 CBY32363.1 - 4.7e-39 132.8 9.8 4.7e-09 36.8 0.3 8.4 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_10 PF13374.6 CBY32363.1 - 1.6e-38 129.5 39.5 9.5e-06 25.3 1.1 12.4 11 1 1 12 12 12 9 Tetratricopeptide repeat TPR_14 PF13428.6 CBY32363.1 - 4.7e-37 123.5 8.9 0.00044 20.8 0.0 12.1 3 2 8 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.6 CBY32363.1 - 4.7e-37 126.3 17.7 1.7e-06 28.4 0.1 8.3 5 2 3 8 8 7 7 Tetratricopeptide repeat TPR_9 PF13371.6 CBY32363.1 - 1e-18 67.2 5.7 0.019 15.1 0.6 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 CBY32363.1 - 1e-15 57.2 17.8 0.27 11.9 0.1 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat NARP1 PF12569.8 CBY32363.1 - 2.1e-13 50.1 4.5 0.0011 17.9 0.0 4.8 1 1 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 CBY32363.1 - 1.5e-10 41.0 10.6 0.089 12.1 0.1 5.3 1 1 2 5 5 5 4 MalT-like TPR region TPR_4 PF07721.14 CBY32363.1 - 2e-10 40.2 0.0 0.69 10.7 0.0 7.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY32363.1 - 1.9e-09 37.2 7.1 1.1e-05 24.8 1.7 4.8 1 1 3 4 4 4 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CBY32363.1 - 3.8e-08 33.1 13.7 0.00091 18.8 0.4 4.0 4 1 0 4 4 4 3 Est1 DNA/RNA binding domain TPR_3 PF07720.12 CBY32363.1 - 4.1e-08 33.0 1.6 0.38 10.8 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY32363.1 - 2.7e-07 30.7 14.0 0.00059 20.0 2.1 5.7 4 2 1 6 6 4 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 CBY32363.1 - 1.4e-05 24.5 4.5 0.32 10.2 1.8 4.3 2 2 0 2 2 2 2 FAT domain TPR_20 PF14561.6 CBY32363.1 - 0.00012 22.3 8.2 0.34 11.2 0.7 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 CBY32363.1 - 0.00031 20.3 19.7 1 8.7 0.7 5.3 1 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP TOM20_plant PF06552.12 CBY32363.1 - 0.00063 19.6 1.7 40 3.9 0.0 5.5 3 2 3 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 Wzy_C_2 PF11846.8 CBY32363.1 - 0.0029 17.6 5.2 0.0052 16.7 1.1 3.3 2 1 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal AAA_13 PF13166.6 CBY32363.1 - 0.0036 16.0 1.0 0.0055 15.4 1.0 1.2 1 0 0 1 1 1 1 AAA domain DUF4807 PF16065.5 CBY32363.1 - 0.0044 16.7 0.1 0.87 9.2 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4807) DUF4810 PF16068.5 CBY32363.1 - 0.0081 16.7 4.0 11 6.7 0.1 6.4 6 1 1 7 7 6 0 Domain of unknown function (DUF4810) DUF627 PF04781.12 CBY32363.1 - 0.016 15.2 3.4 39 4.3 0.1 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 CBY32363.1 - 0.024 14.3 11.6 1 9.0 2.1 4.7 2 2 1 4 4 4 0 Tetratricopeptide repeat-like domain BTAD PF03704.17 CBY32363.1 - 0.065 13.7 10.7 0.17 12.3 3.7 4.3 2 2 0 3 3 3 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 CBY32363.1 - 0.071 13.6 1.3 25 5.3 0.1 3.5 2 2 1 4 4 4 0 Alkyl sulfatase dimerisation SHNi-TPR PF10516.9 CBY32363.1 - 0.086 12.3 1.7 31 4.1 0.0 5.4 6 0 0 6 6 6 0 SHNi-TPR Coatomer_E PF04733.14 CBY32363.1 - 0.16 11.4 3.5 5.9 6.2 0.5 3.4 2 1 2 4 4 3 0 Coatomer epsilon subunit MIT PF04212.18 CBY32363.1 - 0.18 11.9 23.5 4 7.6 0.0 8.9 9 2 2 11 11 10 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 CBY32363.1 - 0.6 10.1 12.9 2.1 8.4 0.6 5.7 6 1 0 6 6 5 0 Mad3/BUB1 homology region 1 DUF5113 PF17140.4 CBY32363.1 - 5.8 6.7 15.6 30 4.4 0.2 6.1 3 3 3 7 7 7 0 Domain of unknown function (DUF5113) SNAP-25 PF00835.19 CBY32364.1 - 7.4e-21 74.2 3.4 1.6e-20 73.2 3.4 1.6 1 0 0 1 1 1 1 SNAP-25 family V-SNARE_C PF12352.8 CBY32364.1 - 7.4e-05 23.0 4.9 0.016 15.5 0.4 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 CBY32364.1 - 0.00028 20.8 6.9 0.001 19.0 6.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) FliJ PF02050.16 CBY32364.1 - 0.021 15.1 3.9 1.5 9.0 0.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein ABC_membrane PF00664.23 CBY32364.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region Laminin_II PF06009.12 CBY32364.1 - 0.13 12.2 7.6 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Rx_N PF18052.1 CBY32364.1 - 0.19 12.0 4.7 0.4 11.0 0.1 2.8 2 1 1 3 3 3 0 Rx N-terminal domain Sec20 PF03908.13 CBY32364.1 - 0.21 11.5 2.3 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 Sec20 UPF0242 PF06785.11 CBY32364.1 - 0.23 11.6 2.8 0.62 10.1 2.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY32364.1 - 0.23 11.5 7.0 3.1 7.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 CBY32364.1 - 0.3 11.4 3.4 1.6 9.1 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 CBY32364.1 - 0.41 10.1 7.3 2.2 7.6 0.4 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.6 CBY32364.1 - 0.44 11.0 7.6 3.1 8.3 0.8 2.3 2 0 0 2 2 2 0 Snapin/Pallidin HisKA_3 PF07730.13 CBY32364.1 - 0.94 10.0 6.1 9.3 6.9 0.3 3.4 3 1 1 4 4 4 0 Histidine kinase FlaC_arch PF05377.11 CBY32364.1 - 1.1 9.7 6.7 5.3 7.5 1.8 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 CBY32364.1 - 1.3 9.7 6.4 4.3 8.0 0.3 2.8 2 1 1 3 3 3 0 SlyX MscS_porin PF12795.7 CBY32364.1 - 2.4 7.7 9.5 1.4 8.4 1.4 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain XhlA PF10779.9 CBY32364.1 - 4.4 7.6 9.8 20 5.5 1.1 3.5 2 2 2 4 4 4 0 Haemolysin XhlA DUF16 PF01519.16 CBY32364.1 - 4.6 7.8 8.3 16 6.0 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 CBY32364.1 - 4.9 7.5 7.3 13 6.1 0.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 CBY32364.1 - 9.4 6.3 8.0 0.88 9.6 0.6 2.5 3 0 0 3 3 2 0 SNARE domain Phenyl_P_gamma PF09662.10 CBY32365.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) RNase_T PF00929.24 CBY32366.1 - 6.6e-15 56.0 0.2 2.4e-14 54.2 0.2 2.0 1 1 0 1 1 1 1 Exonuclease Dynamin_M PF01031.20 CBY32368.1 - 5e-94 314.7 0.0 8.3e-94 314.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CBY32368.1 - 1.7e-50 171.3 0.0 3.1e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CBY32368.1 - 5.6e-26 90.5 0.2 1.7e-25 89.0 0.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CBY32368.1 - 0.00022 21.3 0.0 0.00054 20.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PB1 PF00564.24 CBY32369.1 - 2e-06 27.7 0.2 3.3e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 PB1 domain Branch PF02485.21 CBY32371.1 - 1.7e-11 44.1 0.0 1.9e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2793 PF10983.8 CBY32371.1 - 0.011 15.5 0.8 0.023 14.6 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2793) Cyclin_C PF02984.19 CBY32372.1 - 0.00033 20.7 0.0 0.00051 20.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CBY32373.1 - 0.0059 16.3 0.2 0.0078 16.0 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain EGF_CA PF07645.15 CBY32374.1 - 2.3e-153 498.2 292.3 3.3e-11 43.2 8.6 18.2 17 1 1 18 18 18 18 Calcium-binding EGF domain EGF_3 PF12947.7 CBY32374.1 - 3.6e-127 414.2 288.4 8.2e-11 41.9 10.1 18.6 19 0 0 19 19 19 18 EGF domain cEGF PF12662.7 CBY32374.1 - 1.1e-79 261.8 187.2 2.2e-07 30.7 3.4 19.0 18 1 0 18 18 18 14 Complement Clr-like EGF-like EGF PF00008.27 CBY32374.1 - 3.7e-45 151.8 245.9 3.4e-05 24.0 5.1 19.5 19 0 0 19 19 19 15 EGF-like domain EGF_MSP1_1 PF12946.7 CBY32374.1 - 5.6e-29 99.9 220.7 2.4e-05 24.3 6.0 17.4 17 0 0 17 17 17 14 MSP1 EGF domain 1 hEGF PF12661.7 CBY32374.1 - 1.6e-26 91.9 206.2 0.00034 21.1 4.5 21.1 22 0 0 22 22 22 13 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY32374.1 - 9.9e-16 57.7 257.0 0.001 19.3 10.9 18.8 14 3 5 19 19 19 14 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY32374.1 - 4.5e-14 52.5 218.5 0.0052 17.1 3.8 18.4 18 0 0 18 18 18 12 Pvs28 EGF domain EGF_2 PF07974.13 CBY32374.1 - 0.0091 16.3 10.3 0.0091 16.3 10.3 17.4 18 0 0 18 18 18 6 EGF-like domain Trypsin PF00089.26 CBY32375.1 - 3.2e-54 184.1 0.0 4.2e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY32375.1 - 0.0053 17.7 0.0 0.015 16.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain BRK PF07533.16 CBY32375.1 - 0.034 13.8 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 BRK domain Neur_chan_LBD PF02931.23 CBY32378.1 - 1.6e-59 201.0 0.7 2.4e-59 200.4 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY32378.1 - 2.7e-52 178.2 11.6 8.8e-39 134.0 9.4 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Yip1 PF04893.17 CBY32380.1 - 2.4e-05 24.1 1.0 3.1e-05 23.8 1.0 1.1 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.6 CBY32380.1 - 0.00076 18.4 6.3 0.0024 16.8 3.2 2.0 1 1 1 2 2 2 2 Amino acid permease HlyIII PF03006.20 CBY32380.1 - 0.0056 16.4 2.6 0.0063 16.3 2.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-DISM_7TM PF07695.11 CBY32380.1 - 0.021 14.7 6.8 0.025 14.5 6.8 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling AbrB PF05145.12 CBY32380.1 - 0.042 12.8 1.1 0.046 12.7 1.1 1.0 1 0 0 1 1 1 0 Transition state regulatory protein AbrB AA_permease_2 PF13520.6 CBY32381.1 - 2.6e-20 72.7 17.9 3.1e-20 72.4 17.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2516 PF10724.9 CBY32381.1 - 0.16 12.3 1.5 0.39 11.0 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) Ion_trans PF00520.31 CBY32382.1 - 4.1e-25 88.4 14.5 7.7e-25 87.5 14.5 1.4 1 0 0 1 1 1 1 Ion transport protein TRP_2 PF08344.11 CBY32382.1 - 2e-24 85.6 2.0 4e-24 84.6 2.0 1.5 1 0 0 1 1 1 1 Transient receptor ion channel II PKD_channel PF08016.12 CBY32382.1 - 1.9e-14 53.2 12.2 6.8e-14 51.4 12.2 1.8 1 1 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 CBY32382.1 - 2e-06 28.3 0.0 0.00046 20.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32382.1 - 0.062 13.6 0.0 6.6 7.2 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PBC PF03792.13 CBY32382.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 PBC domain Plectin PF00681.20 CBY32383.1 - 1.1e-05 25.2 0.0 0.001 18.9 0.0 3.3 4 0 0 4 4 4 1 Plectin repeat DUF1992 PF09350.10 CBY32383.1 - 0.03 14.5 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) ATP-gua_Ptrans PF00217.19 CBY32384.1 - 3.1e-62 209.8 0.0 4.2e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY32384.1 - 8.5e-24 83.7 0.1 2.7e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Sulfate_transp PF00916.20 CBY32385.1 - 2.2e-64 217.6 16.3 2.7e-64 217.3 16.3 1.0 1 0 0 1 1 1 1 Sulfate permease family ABC_membrane PF00664.23 CBY32386.1 - 5.4e-36 124.7 2.0 7.5e-36 124.2 2.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY32386.1 - 4.1e-32 111.6 0.0 1.9e-31 109.4 0.0 2.2 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CBY32386.1 - 2.5e-08 33.6 0.0 1e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBY32386.1 - 1e-05 24.9 0.2 0.00075 18.8 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.17 CBY32386.1 - 0.0029 17.3 0.0 0.76 9.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CBY32386.1 - 0.0034 17.1 0.5 0.048 13.4 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBY32386.1 - 0.0056 17.1 2.1 0.12 12.8 0.3 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_membrane_2 PF06472.15 CBY32386.1 - 0.008 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Ploopntkinase3 PF18751.1 CBY32386.1 - 0.01 15.8 0.0 0.058 13.3 0.0 2.3 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 APS_kinase PF01583.20 CBY32386.1 - 0.012 15.5 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_22 PF13401.6 CBY32386.1 - 0.027 14.8 0.6 0.28 11.4 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBY32386.1 - 0.036 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 CBY32386.1 - 0.038 13.6 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CBY32386.1 - 0.039 13.5 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY32386.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 CBY32386.1 - 0.092 13.3 0.2 0.29 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CBY32386.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 CBY32386.1 - 0.16 12.0 0.1 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY32386.1 - 0.2 12.0 0.5 0.48 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 CBY32386.1 - 0.2 11.9 3.0 1.1 9.6 0.8 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit KH_6 PF15985.5 CBY32387.1 - 3.4e-05 24.1 0.1 9.3e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCCH_3 PF15663.5 CBY32388.1 - 2.8e-09 37.2 19.3 9.4e-09 35.5 4.6 2.4 1 1 1 2 2 2 2 Zinc-finger containing family Torus PF16131.5 CBY32388.1 - 2.7e-07 31.3 19.9 0.0046 17.6 0.8 3.8 1 1 3 4 4 4 3 Torus domain zf-CCCH PF00642.24 CBY32388.1 - 1e-06 28.5 30.9 0.011 15.6 5.0 4.3 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY32388.1 - 0.014 15.4 33.2 0.041 13.9 1.5 4.6 4 0 0 4 4 4 0 Zinc finger domain PWI PF01480.17 CBY32389.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 PWI domain Thyroglobulin_1 PF00086.18 CBY32395.1 - 0.00024 20.7 3.1 0.00024 20.7 3.1 1.8 2 1 0 2 2 2 1 Thyroglobulin type-1 repeat zf-RING_5 PF14634.6 CBY32397.1 - 1.2e-06 28.4 6.7 2.1e-06 27.6 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY32397.1 - 1.2e-05 25.5 6.3 2.2e-05 24.7 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY32397.1 - 2.2e-05 24.2 6.4 4e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY32397.1 - 0.00057 19.8 7.4 0.001 19.1 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY32397.1 - 0.0012 18.6 7.9 0.0026 17.6 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) YabA PF06156.13 CBY32397.1 - 0.0071 17.0 2.5 0.013 16.1 2.5 1.4 1 0 0 1 1 1 1 Initiation control protein YabA FYVE PF01363.21 CBY32397.1 - 0.02 15.0 5.1 0.038 14.1 5.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger DUF5082 PF16888.5 CBY32397.1 - 0.036 14.3 0.6 0.06 13.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) KxDL PF10241.9 CBY32397.1 - 0.2 12.0 1.0 4.6 7.6 0.1 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein Med9 PF07544.13 CBY32397.1 - 0.21 11.7 2.4 0.48 10.6 2.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3287 PF11690.8 CBY32397.1 - 0.24 11.1 1.4 1.3 8.7 1.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) TMPIT PF07851.13 CBY32397.1 - 0.57 9.4 3.1 0.84 8.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-C3HC4_4 PF15227.6 CBY32397.1 - 0.79 9.9 9.0 3.6 7.8 8.6 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CBY32397.1 - 1.6 8.5 11.6 3.3 7.5 11.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 CBY32399.1 - 9.9e-65 218.5 0.0 1.4e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32399.1 - 1.4e-32 113.0 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY32399.1 - 3.3e-08 33.2 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY32399.1 - 9e-07 28.0 0.0 2.4e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CBY32399.1 - 0.00017 21.3 0.0 0.43 10.2 0.0 2.5 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CBY32399.1 - 0.005 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 CBY32399.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NTP_transferase PF00483.23 CBY32400.1 - 2.4e-22 79.7 0.0 3.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CBY32400.1 - 2.7e-07 30.0 0.5 6.4e-06 25.7 0.3 2.4 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CBY32400.1 - 0.0004 20.8 0.0 0.00069 20.0 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CBY32400.1 - 0.0037 17.0 0.2 0.0086 15.8 0.2 1.7 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Tubulin PF00091.25 CBY32401.1 - 0.017 15.3 0.0 0.02 15.1 0.0 1.0 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Arf PF00025.21 CBY32403.1 - 7.3e-62 207.9 0.2 8.1e-62 207.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY32403.1 - 5.2e-12 46.0 0.0 8.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY32403.1 - 9e-10 38.4 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBY32403.1 - 1.2e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBY32403.1 - 2.1e-09 37.0 0.7 0.00018 20.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY32403.1 - 9.1e-08 31.7 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY32403.1 - 6.1e-06 26.3 0.0 9.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY32403.1 - 5.6e-05 23.4 0.0 8.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CBY32403.1 - 0.0021 17.7 0.6 1.8 8.1 0.4 2.1 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBY32403.1 - 0.0049 16.8 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CBY32403.1 - 0.0077 16.8 0.2 0.01 16.4 0.2 1.5 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 CBY32403.1 - 0.0085 15.6 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 CBY32403.1 - 0.012 14.8 0.1 0.026 13.7 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CBY32403.1 - 0.041 14.4 0.1 0.07 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.21 CBY32403.1 - 0.045 12.0 0.0 0.064 11.5 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA PF00004.29 CBY32403.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY32403.1 - 0.079 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CBY32403.1 - 0.087 12.7 1.9 1.3 8.9 0.5 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CBY32403.1 - 0.091 13.1 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 CBY32403.1 - 0.1 12.5 0.2 0.21 11.5 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 CBY32403.1 - 0.12 12.0 0.3 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 CBY32403.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBY32403.1 - 0.14 12.2 0.2 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain DLIC PF05783.11 CBY32403.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 CBY32403.1 - 0.18 11.4 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPK2 PF03976.14 CBY32403.1 - 0.18 11.2 0.2 0.36 10.3 0.1 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HLH PF00010.26 CBY32404.1 - 2e-14 53.2 1.4 5.7e-14 51.8 1.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1122 PF06557.11 CBY32404.1 - 0.17 11.3 0.2 0.26 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Lactonase PF10282.9 CBY32405.1 - 0.00028 20.2 0.0 0.019 14.2 0.0 2.3 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller Babuvirus_MP PF07234.11 CBY32406.1 - 0.06 13.5 0.4 0.1 12.8 0.4 1.3 1 0 0 1 1 1 0 Movement and RNA silencing protein NitrOD5 PF11537.8 CBY32406.1 - 0.15 12.2 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 Astacin PF01400.24 CBY32407.1 - 1.3e-44 152.1 1.8 2.5e-44 151.2 1.8 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) TSP_1 PF00090.19 CBY32407.1 - 9.7e-38 128.2 101.0 4.2e-09 36.5 13.9 7.6 6 0 0 6 6 6 5 Thrombospondin type 1 domain Ldl_recept_a PF00057.18 CBY32407.1 - 3.8e-06 27.0 2.5 3.8e-06 27.0 2.5 4.7 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A EamA PF00892.20 CBY32408.1 - 0.1 12.7 38.7 0.089 13.0 12.1 4.0 2 2 0 2 2 2 0 EamA-like transporter family SLATT_5 PF18160.1 CBY32408.1 - 0.26 10.6 1.8 0.67 9.3 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 HRG PF16954.5 CBY32408.1 - 0.83 10.1 0.0 0.83 10.1 0.0 3.5 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene YrhK PF14145.6 CBY32408.1 - 2.1 8.3 13.7 2.3 8.1 1.4 3.3 2 1 1 3 3 3 0 YrhK-like protein Kelch_1 PF01344.25 CBY32409.1 - 8.3e-07 28.5 0.2 1.1 8.9 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBY32409.1 - 7e-05 22.7 1.6 0.96 9.5 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY32409.1 - 0.00024 21.0 2.0 3.1 7.9 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY32409.1 - 0.00026 21.2 6.2 11 6.5 0.0 5.1 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBY32409.1 - 0.028 14.4 0.4 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 CBY32409.1 - 0.36 11.2 3.6 2.1 8.7 0.0 3.4 4 0 0 4 4 4 0 Galactose oxidase, central domain PBP1_TM PF14812.6 CBY32410.1 - 0.00027 21.2 1.0 0.00037 20.8 1.0 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_1 PF00078.27 CBY32411.1 - 2.2e-12 47.0 0.9 7.9e-12 45.2 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY32411.1 - 2.3e-09 37.2 0.0 8.8e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY32411.1 - 6e-07 29.7 0.1 3.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY32411.1 - 1.2e-05 25.3 0.2 1.2e-05 25.3 0.2 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CBY32411.1 - 0.00098 19.7 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease VirArc_Nuclease PF12187.8 CBY32411.1 - 0.015 14.9 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 Viral/Archaeal nuclease gag-asp_proteas PF13975.6 CBY32411.1 - 0.14 12.7 0.0 0.55 10.8 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Tmemb_185A PF10269.9 CBY32412.1 - 0.0077 15.9 5.4 0.011 15.5 5.4 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Apolipoprotein PF01442.18 CBY32412.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.10 CBY32412.1 - 0.036 14.2 3.4 2.5 8.3 0.9 3.0 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF4079 PF13301.6 CBY32412.1 - 0.043 14.0 0.1 0.078 13.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3813 PF12758.7 CBY32412.1 - 0.069 13.5 0.0 2.1 8.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) T7SS_ESX_EspC PF10824.8 CBY32412.1 - 0.087 13.3 1.1 0.19 12.2 1.1 1.5 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm Dodecin PF07311.12 CBY32412.1 - 0.84 9.9 3.0 1.4 9.2 0.6 2.5 1 1 1 2 2 2 0 Dodecin MT0933_antitox PF14013.6 CBY32412.1 - 1.4 9.2 17.1 2.7e+02 2.0 17.1 3.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF2207 PF09972.9 CBY32412.1 - 8.9 4.9 8.4 56 2.3 8.4 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FAM176 PF14851.6 CBY32413.1 - 0.0017 18.1 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 2 FAM176 family DUF1180 PF06679.12 CBY32413.1 - 0.022 15.2 1.2 0.052 14.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Syndecan PF01034.20 CBY32413.1 - 0.18 11.8 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain BT1 PF03092.16 CBY32413.1 - 0.27 9.4 0.1 0.38 8.9 0.1 1.1 1 0 0 1 1 1 0 BT1 family TPR_12 PF13424.6 CBY32414.1 - 6.4e-08 32.8 5.0 0.031 14.5 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY32414.1 - 0.002 18.1 6.6 2.6 8.4 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY32414.1 - 0.0095 16.1 1.3 0.75 10.2 0.0 4.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY32414.1 - 0.017 15.9 1.8 32 5.7 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY32414.1 - 0.23 11.3 3.0 2.7 8.0 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY32414.1 - 2.2 8.6 7.1 3 8.2 2.1 3.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Dynein_C PF18199.1 CBY32415.1 - 2e-112 375.4 0.0 2.3e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY32415.1 - 2.7e-05 24.0 0.0 5.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Herpes_BTRF1 PF04682.12 CBY32415.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region Pan3_PK PF18101.1 CBY32416.1 - 1.4e-40 138.4 0.0 2.8e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CBY32416.1 - 2.8e-08 33.5 0.3 5.6e-08 32.5 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32416.1 - 0.0054 16.1 0.1 0.0093 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CREPT PF16566.5 CBY32417.1 - 1.4e-11 44.8 2.2 1.4e-11 44.8 2.2 2.4 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CBY32417.1 - 1.6e-11 44.9 0.7 9.7e-11 42.3 0.0 2.8 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Med19 PF10278.9 CBY32417.1 - 5.5e-05 23.2 2.1 5.5e-05 23.2 2.1 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 CTK3 PF12243.8 CBY32417.1 - 0.0035 17.3 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Peptidase_S49_N PF08496.10 CBY32417.1 - 0.53 10.3 11.1 0.26 11.3 6.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thg1C PF14413.6 CBY32417.1 - 3 8.0 8.3 1.7 8.8 4.1 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain Ank_2 PF12796.7 CBY32418.1 - 2.5e-20 72.8 0.0 2.4e-09 37.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32418.1 - 2.4e-11 43.7 0.0 6.6e-06 26.3 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY32418.1 - 6.8e-11 41.4 0.1 0.018 15.5 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CBY32418.1 - 7.8e-07 29.5 0.0 0.00082 19.9 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY32418.1 - 1.7e-06 28.2 0.0 0.57 10.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat SOCS_box PF07525.16 CBY32418.1 - 0.0013 19.0 2.8 0.0029 17.9 2.8 1.6 1 0 0 1 1 1 1 SOCS box WD40 PF00400.32 CBY32419.1 - 1.3e-19 70.1 8.4 1.3e-06 29.0 0.6 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY32419.1 - 1.6e-09 37.9 0.2 0.00024 21.3 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY32419.1 - 0.00015 21.2 0.1 0.013 14.8 0.3 2.3 2 0 0 2 2 2 2 WD40-like domain F_actin_bind PF08919.10 CBY32419.1 - 0.028 14.5 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 F-actin binding Dscam_C PF12355.8 CBY32419.1 - 0.065 14.2 3.3 0.096 13.7 2.1 1.9 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Ras PF00071.22 CBY32420.1 - 8.8e-55 184.7 0.1 1e-54 184.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY32420.1 - 7.8e-21 74.5 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY32420.1 - 1.7e-10 40.7 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY32420.1 - 0.00012 22.1 1.6 0.16 11.9 0.0 2.1 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY32420.1 - 0.00019 21.0 0.1 0.0009 18.8 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY32420.1 - 0.0041 17.2 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY32420.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 CBY32420.1 - 0.12 11.4 0.0 11 5.0 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit zf-B_box PF00643.24 CBY32421.1 - 0.066 13.4 10.7 0.089 13.0 10.7 1.2 1 0 0 1 1 1 0 B-box zinc finger Vps53_N PF04100.12 CBY32422.1 - 0.00039 19.5 0.6 0.0004 19.5 0.6 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal FliT PF05400.13 CBY32422.1 - 0.011 16.5 1.8 0.013 16.2 1.8 1.1 1 0 0 1 1 1 0 Flagellar protein FliT YgaB PF14182.6 CBY32422.1 - 0.037 14.4 0.8 0.044 14.2 0.8 1.2 1 0 0 1 1 1 0 YgaB-like protein TPT PF03151.16 CBY32423.1 - 7e-11 42.0 18.6 9.1e-11 41.6 18.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY32423.1 - 0.0035 17.5 34.6 0.2 11.8 15.7 2.7 2 1 0 2 2 2 2 EamA-like transporter family DSPc PF00782.20 CBY32424.1 - 9.3e-14 51.4 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY32424.1 - 0.0074 16.4 0.0 0.046 13.8 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY32424.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY32424.1 - 0.041 13.9 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PriX PF18689.1 CBY32424.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Primase X Ion_trans PF00520.31 CBY32425.1 - 8.1e-35 120.2 18.8 1.2e-34 119.6 18.8 1.2 1 0 0 1 1 1 1 Ion transport protein BTB_2 PF02214.22 CBY32425.1 - 6e-18 65.0 0.2 9.4e-17 61.2 0.0 2.9 3 0 0 3 3 3 1 BTB/POZ domain Ion_trans_2 PF07885.16 CBY32425.1 - 4.9e-12 45.6 6.8 1.7e-11 43.9 6.8 2.0 1 0 0 1 1 1 1 Ion channel VWA_3 PF13768.6 CBY32425.1 - 8.3e-09 35.6 0.0 2.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY32425.1 - 1.9e-05 25.2 0.0 4.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY32425.1 - 0.00038 20.7 0.0 0.00078 19.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain PKD_channel PF08016.12 CBY32425.1 - 0.12 11.1 12.3 0.027 13.2 3.9 2.4 1 1 1 2 2 2 0 Polycystin cation channel Rhodanese PF00581.20 CBY32426.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain HPD PF05044.12 CBY32427.1 - 4.2e-78 260.6 1.7 4.2e-78 260.6 1.7 1.6 2 0 0 2 2 2 1 Homeo-prospero domain Com_YlbF PF06133.11 CBY32427.1 - 0.55 10.9 5.8 0.2 12.3 0.4 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ion_trans PF00520.31 CBY32428.1 - 2.5e-15 56.4 15.8 3.5e-15 55.9 15.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY32428.1 - 2.5e-13 49.9 0.0 4.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 CBY32428.1 - 0.069 12.8 1.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein N-terminal Vinculin PF01044.19 CBY32430.1 - 8.5e-15 54.1 15.6 1.1e-14 53.7 14.8 1.4 1 1 0 1 1 1 1 Vinculin family KASH_CCD PF14662.6 CBY32430.1 - 0.012 15.5 10.7 0.012 15.5 10.7 3.8 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 CBY32430.1 - 0.016 15.4 10.5 0.016 15.4 10.5 3.9 3 2 1 4 4 4 0 Tropomyosin like Fez1 PF06818.15 CBY32430.1 - 0.087 13.3 32.3 0.31 11.5 25.1 3.3 1 1 1 2 2 2 0 Fez1 FAM76 PF16046.5 CBY32430.1 - 0.56 9.5 21.3 0.017 14.5 13.2 2.2 2 1 0 2 2 2 0 FAM76 protein Fib_alpha PF08702.10 CBY32430.1 - 0.62 10.2 32.2 0.16 12.1 6.5 4.3 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.13 CBY32430.1 - 1.2 8.9 16.6 0.17 11.7 10.4 2.5 2 1 1 3 3 3 0 Nsp1-like C-terminal region XRN_M PF17846.1 CBY32430.1 - 1.3 7.9 16.1 0.26 10.2 12.3 1.7 2 0 0 2 2 2 0 Xrn1 helical domain ADIP PF11559.8 CBY32430.1 - 1.5 8.9 34.7 1.6 8.8 14.0 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CBY32430.1 - 1.8 7.8 18.6 1.1 8.5 13.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 CBY32430.1 - 1.8 7.3 24.4 0.33 9.7 19.9 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.12 CBY32430.1 - 1.8 8.6 29.1 0.66 10.0 18.7 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY32430.1 - 1.8 8.6 18.6 0.93 9.5 5.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CBY32430.1 - 2.3 8.9 18.0 24 5.7 10.9 4.2 3 1 0 3 3 3 0 SlyX Lebercilin PF15619.6 CBY32430.1 - 2.6 7.7 34.3 5.9 6.5 17.3 4.5 3 2 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 CBY32430.1 - 3.5 5.4 17.9 6 4.7 17.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 CBY32430.1 - 3.5 7.8 25.7 0.038 14.2 14.8 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) HSF_DNA-bind PF00447.17 CBY32431.1 - 2e-17 63.6 1.8 3.9e-17 62.7 1.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding PAX PF00292.18 CBY32432.1 - 4e-69 230.3 0.5 6.3e-69 229.7 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY32432.1 - 1e-22 79.7 3.8 2.3e-22 78.6 3.8 1.7 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 CBY32432.1 - 8e-05 22.3 1.4 0.00014 21.5 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 CBY32432.1 - 0.00054 20.5 0.2 0.0023 18.5 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 CBY32432.1 - 0.0045 16.6 0.1 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 InsA C-terminal domain HTH_28 PF13518.6 CBY32432.1 - 0.043 13.9 0.4 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 CBY32432.1 - 0.089 12.7 1.2 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Glutaredoxin PF00462.24 CBY32433.1 - 1.9e-20 72.8 0.1 2.9e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CBY32433.1 - 0.00017 21.6 0.1 0.00041 20.3 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 CBY32433.1 - 0.00035 20.9 0.1 0.00069 20.0 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 CBY32433.1 - 0.0014 19.1 0.4 0.0036 17.7 0.4 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY32433.1 - 0.0027 17.9 0.8 1.4 9.1 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin DSBA PF01323.20 CBY32433.1 - 0.0044 16.8 1.6 0.049 13.4 1.6 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain GST_N_3 PF13417.6 CBY32433.1 - 0.036 14.5 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Kringle PF00051.18 CBY32434.1 - 3.8e-12 46.3 5.8 7.8e-12 45.4 5.8 1.6 1 1 0 1 1 1 1 Kringle domain Kringle PF00051.18 CBY32435.1 - 1.9e-18 66.6 9.2 4.6e-18 65.3 6.5 2.1 2 0 0 2 2 2 1 Kringle domain Phage-MuB_C PF09077.11 CBY32435.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Mu B transposition protein, C terminal TFIIA PF03153.13 CBY32436.1 - 3.1 7.7 10.1 4.8 7.1 10.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Carb_anhydrase PF00194.21 CBY32437.1 - 3.5e-40 138.2 3.6 4.8e-40 137.7 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase EGF_2 PF07974.13 CBY32438.1 - 8.8e-25 86.8 229.5 0.00014 22.1 8.9 14.3 13 1 1 14 14 14 11 EGF-like domain EGF PF00008.27 CBY32438.1 - 1.6e-23 82.7 186.8 5.9e-06 26.5 8.3 15.1 14 1 0 14 14 14 11 EGF-like domain EGF_CA PF07645.15 CBY32438.1 - 7.6e-11 42.0 48.7 1.3e-07 31.7 10.9 14.8 9 4 6 15 15 15 4 Calcium-binding EGF domain hEGF PF12661.7 CBY32438.1 - 2.4e-05 24.8 36.3 0.00039 20.9 3.5 16.4 17 0 0 17 17 17 7 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY32438.1 - 0.00012 22.3 11.9 0.00035 20.8 1.8 14.4 14 1 1 15 15 15 3 Pvs28 EGF domain EGF_3 PF12947.7 CBY32438.1 - 0.00047 20.3 7.0 0.00047 20.3 7.0 14.6 11 2 3 14 14 14 5 EGF domain Collectrin PF16959.5 CBY32438.1 - 0.016 15.0 0.9 0.025 14.4 0.9 1.2 1 0 0 1 1 1 0 Renal amino acid transporter EF-hand_6 PF13405.6 CBY32441.1 - 2.5e-07 30.1 2.0 0.094 12.7 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY32441.1 - 4.2e-07 30.3 0.2 0.009 16.4 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY32441.1 - 4.7e-05 22.6 2.7 0.082 12.5 0.0 4.6 4 1 1 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY32441.1 - 0.011 15.6 6.2 0.011 15.5 0.1 3.3 3 1 1 4 4 4 0 EF-hand domain pair MBOAT_2 PF13813.6 CBY32441.1 - 0.048 13.9 0.2 0.086 13.1 0.2 1.4 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Fungal_TACC PF12709.7 CBY32442.1 - 0.077 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins EF-hand_6 PF13405.6 CBY32443.1 - 2.1e-07 30.3 2.2 0.058 13.3 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY32443.1 - 6.9e-07 29.6 0.1 0.005 17.3 0.1 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY32443.1 - 5.2e-05 22.5 2.5 0.052 13.1 0.0 4.6 4 1 1 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY32443.1 - 0.0018 18.1 4.5 0.0067 16.2 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY32444.1 - 5.6e-05 22.7 0.2 0.029 14.3 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBY32444.1 - 0.00023 20.5 3.8 0.027 14.0 0.0 3.9 4 1 1 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY32444.1 - 0.00074 19.3 4.8 0.003 17.4 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY32444.1 - 0.00082 19.8 0.2 0.002 18.6 0.1 1.7 2 1 0 2 2 2 1 EF-hand domain pair O-FucT PF10250.9 CBY32445.1 - 7.9e-12 45.5 0.3 1.6e-10 41.3 0.3 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ABC_tran PF00005.27 CBY32446.1 - 1.3e-22 80.7 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY32446.1 - 6.6e-06 26.1 0.2 0.053 13.3 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY32446.1 - 0.00057 19.4 0.4 0.012 15.0 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY32446.1 - 0.00069 19.6 0.2 0.0042 17.0 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase ATPase_2 PF01637.18 CBY32446.1 - 0.0024 17.8 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CBY32446.1 - 0.0056 16.7 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY32446.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CBY32446.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBY32446.1 - 0.051 13.3 0.0 1.9 8.1 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CBY32446.1 - 0.057 13.9 0.3 0.057 13.9 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY32446.1 - 0.062 13.7 0.1 0.082 13.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 CBY32446.1 - 0.066 13.3 0.3 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_29 PF13555.6 CBY32446.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CBY32446.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBY32446.1 - 0.11 12.7 0.1 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBY32446.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 CBY32446.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CBY32446.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 CBY32446.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 CBY32446.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_35 PF01301.19 CBY32448.1 - 2.5e-87 293.5 0.1 6.2e-87 292.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY32448.1 - 1.3e-09 37.8 0.0 2.7e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Beta-galactosidase FemAB_like PF04339.12 CBY32449.1 - 0.12 11.4 0.7 0.11 11.6 0.7 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Ammonium_transp PF00909.21 CBY32450.1 - 1.1e-85 287.8 18.7 2.7e-52 177.8 10.8 2.5 2 1 0 2 2 2 2 Ammonium Transporter Family DUF1129 PF06570.11 CBY32450.1 - 0.0011 18.5 1.7 0.0011 18.5 1.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1129) ThrE PF06738.12 CBY32450.1 - 0.19 11.1 6.2 0.1 12.0 0.7 2.7 2 0 0 2 2 2 0 Putative threonine/serine exporter Glyco_transf_7N PF13733.6 CBY32451.1 - 1.1e-47 161.0 0.3 1.9e-47 160.2 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY32451.1 - 2.5e-16 59.1 0.2 6.5e-16 57.8 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase O-FucT PF10250.9 CBY32451.1 - 0.00044 20.0 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EGF_3 PF12947.7 CBY32452.1 - 0.056 13.7 1.0 0.12 12.6 1.0 1.6 1 0 0 1 1 1 0 EGF domain zf-RING_UBOX PF13445.6 CBY32455.1 - 6.2e-05 22.9 5.2 0.00013 21.9 5.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY32455.1 - 0.00015 21.5 9.3 0.00044 20.1 9.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY32455.1 - 0.00039 20.3 9.8 0.00099 19.0 9.6 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY32455.1 - 0.00078 19.7 13.2 0.0029 17.9 13.2 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY32455.1 - 0.0012 18.7 9.5 0.0032 17.3 9.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY32455.1 - 0.0018 18.1 10.4 0.026 14.4 10.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY32455.1 - 0.014 15.2 7.5 0.014 15.2 7.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 CBY32455.1 - 0.018 15.2 5.7 0.043 13.9 5.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger Med20 PF08612.11 CBY32455.1 - 0.1 12.0 0.9 0.18 11.1 0.9 1.3 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Vps39_2 PF10367.9 CBY32455.1 - 1.2 9.6 7.7 3.5 8.1 7.7 1.8 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 CBY32455.1 - 3.1 8.2 11.6 12 6.3 11.4 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain RVT_1 PF00078.27 CBY32457.1 - 3.2e-32 111.9 0.1 7.8e-32 110.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY32458.1 - 3.6e-05 24.0 0.0 9.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-C4 PF00105.18 CBY32459.1 - 2e-28 98.6 14.3 4.5e-28 97.5 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Cys_Met_Meta_PP PF01053.20 CBY32461.1 - 4.2e-144 479.8 0.0 4.8e-144 479.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CBY32461.1 - 4.1e-06 25.6 0.0 5.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CBY32461.1 - 4.7e-06 25.8 0.3 7e-06 25.2 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBY32461.1 - 0.011 15.1 0.0 0.04 13.2 0.0 1.7 1 1 1 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family GHL10 PF02638.15 CBY32462.1 - 0.018 14.1 0.0 0.02 14.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase-like 10 RNase_H2_suC PF08615.11 CBY32462.1 - 0.045 13.9 0.0 0.94 9.6 0.0 2.3 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_S9 PF00326.21 CBY32463.1 - 1.3e-48 165.3 0.0 2.1e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBY32463.1 - 1.7e-46 158.6 0.4 2.3e-46 158.2 0.4 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 PF02129.18 CBY32463.1 - 5.3e-09 36.1 0.0 3.4e-08 33.4 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CBY32463.1 - 5.8e-07 29.4 0.0 3.9e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 CBY32463.1 - 0.0039 15.9 0.5 0.039 12.6 0.5 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 CBY32463.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY32463.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 CBY32463.1 - 0.027 13.3 0.2 0.048 12.5 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.16 CBY32463.1 - 0.052 13.4 0.2 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 CBY32463.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Rad51 PF08423.11 CBY32464.1 - 4.6e-23 81.8 0.0 5.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 CBY32464.1 - 2.6e-09 36.8 0.0 1.3e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CBY32464.1 - 4e-08 33.1 0.0 5.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CBY32464.1 - 5.9e-08 32.4 0.0 8.3e-06 25.3 0.0 2.5 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain RecA PF00154.21 CBY32464.1 - 0.00015 21.4 0.0 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein PhoH PF02562.16 CBY32464.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 CBY32464.1 - 0.0041 16.4 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBY32464.1 - 0.0044 16.8 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CBY32464.1 - 0.024 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY32464.1 - 0.057 13.8 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY32464.1 - 0.072 13.4 0.3 1 9.6 0.3 2.2 1 1 0 1 1 1 0 AAA domain SpoIIE PF07228.12 CBY32465.1 - 2.9e-14 53.4 0.1 4.4e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBY32465.1 - 4.9e-07 29.6 0.4 0.00084 19.0 0.1 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CBY32465.1 - 9.6e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C RNA_pol_Rbc25 PF08292.12 CBY32466.1 - 4.7e-24 85.1 2.1 9.8e-22 77.6 2.1 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CBY32466.1 - 9.7e-16 57.9 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CBY32466.1 - 0.081 13.3 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain GBP PF02263.19 CBY32467.1 - 1.2e-63 214.8 0.2 2e-63 214.1 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain 7tm_1 PF00001.21 CBY32467.1 - 0.0028 17.0 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3566 PF12089.8 CBY32467.1 - 0.057 13.8 0.7 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) FA_desaturase PF00487.24 CBY32467.1 - 0.18 11.6 0.1 0.4 10.5 0.0 1.5 2 0 0 2 2 2 0 Fatty acid desaturase Zona_pellucida PF00100.23 CBY32468.1 - 3.5e-20 72.9 2.3 4e-20 72.7 2.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Metallophos PF00149.28 CBY32469.1 - 4.9e-41 141.5 0.0 6.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBY32469.1 - 6.7e-20 71.3 0.2 1.3e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Forkhead PF00250.18 CBY32470.1 - 1.7e-21 76.3 0.1 3.9e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain SH2 PF00017.24 CBY32473.1 - 2.2e-14 53.3 0.2 2.8e-13 49.8 0.0 2.7 2 1 0 2 2 2 1 SH2 domain SH3_9 PF14604.6 CBY32473.1 - 1e-12 47.7 0.7 2.4e-08 33.7 0.1 2.9 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY32473.1 - 9.9e-10 37.9 0.5 0.0033 17.0 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY32473.1 - 9.4e-06 25.2 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH2 PF00017.24 CBY32474.1 - 1.1e-19 70.3 0.2 2e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 SH2 domain SH3_9 PF14604.6 CBY32474.1 - 1.2e-18 66.7 0.3 2.3e-09 37.0 0.1 3.1 2 1 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CBY32474.1 - 1.1e-16 60.1 0.2 3.4e-08 33.0 0.0 3.2 3 1 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 CBY32474.1 - 1.8e-11 43.5 0.0 2.5e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain MbtH PF03621.13 CBY32474.1 - 0.16 11.4 1.0 0.26 10.8 0.1 1.8 2 0 0 2 2 2 0 MbtH-like protein Trimer_CC PF08954.11 CBY32475.1 - 0.0039 16.7 1.9 0.4 10.3 0.1 2.6 2 0 0 2 2 2 2 Trimerisation motif TSC22 PF01166.18 CBY32475.1 - 0.03 14.6 1.2 0.03 14.6 1.2 3.5 2 2 1 3 3 3 0 TSC-22/dip/bun family MetOD2 PF18548.1 CBY32475.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.7 3 0 0 3 3 3 0 Metanogen output domain 2 ADIP PF11559.8 CBY32475.1 - 0.43 10.7 20.7 0.07 13.2 13.5 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 CBY32475.1 - 0.55 10.3 8.7 0.33 11.0 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 CBY32475.1 - 1.3 9.4 19.9 2 8.8 19.9 1.4 1 1 0 1 1 1 0 Fez1 Occludin_ELL PF07303.13 CBY32475.1 - 1.4 9.6 15.0 0.11 13.3 8.1 2.1 1 1 1 2 2 2 0 Occludin homology domain CENP-H PF05837.12 CBY32475.1 - 2.2 8.7 19.2 18 5.8 19.2 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) YvrJ PF12841.7 CBY32475.1 - 5 6.7 5.6 1.2 8.7 0.2 2.7 4 0 0 4 4 4 0 YvrJ protein family P4Ha_N PF08336.11 CBY32475.1 - 5.4 7.0 16.9 2 8.4 1.8 2.7 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RNase_T PF00929.24 CBY32478.1 - 2.5e-13 50.9 0.0 3.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBY32478.1 - 0.021 14.5 0.0 0.094 12.4 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease PA26 PF04636.13 CBY32479.1 - 0.66 8.8 5.1 1.2 8.0 5.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4404 PF14357.6 CBY32479.1 - 5.9 7.6 13.2 3.9 8.2 0.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) RNase_T PF00929.24 CBY32480.1 - 4.2e-11 43.7 0.0 1e-10 42.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease DUF778 PF05608.12 CBY32480.1 - 3.5 7.9 5.6 3.9 7.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF778) UQ_con PF00179.26 CBY32481.1 - 3.2e-20 72.2 0.1 4e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY32481.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 CBY32482.1 - 4.5e-19 68.5 0.0 6.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyltransferase PF01553.21 CBY32483.1 - 1.3e-21 76.6 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBY32483.1 - 2.4e-16 59.6 1.8 4.5e-16 58.7 1.8 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Adaptin_N PF01602.20 CBY32484.1 - 8.9e-117 390.8 8.1 1.2e-116 390.4 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBY32484.1 - 1.1e-50 171.7 0.1 2.6e-50 170.5 0.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBY32484.1 - 2.1e-35 121.3 0.0 7.3e-35 119.6 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CBY32484.1 - 7.2e-18 64.8 1.3 1.2e-07 32.0 0.0 6.1 3 2 4 7 7 7 4 HEAT repeats Cnd1 PF12717.7 CBY32484.1 - 1.2e-13 51.5 14.4 2.5e-05 24.4 0.9 5.1 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY32484.1 - 4.6e-05 23.3 2.1 27 5.4 0.0 6.6 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CBY32484.1 - 0.0034 17.8 2.0 0.84 10.2 0.2 5.0 6 1 1 7 7 7 1 HEAT-like repeat DNA_alkylation PF08713.11 CBY32484.1 - 0.0042 16.8 0.1 0.015 15.0 0.1 2.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme HEAT_PBS PF03130.16 CBY32484.1 - 0.017 15.7 0.0 13 6.8 0.1 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 CBY32484.1 - 0.036 14.1 0.1 9.6 6.4 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat 6PF2K PF01591.18 CBY32485.1 - 2.7e-81 272.2 0.5 3.9e-81 271.6 0.5 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBY32485.1 - 4.3e-39 134.2 0.0 7.2e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 CBY32485.1 - 0.0002 20.9 0.0 0.00046 19.7 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBY32485.1 - 0.0005 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY32485.1 - 0.0055 17.2 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBY32485.1 - 0.013 15.9 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol_B PF00136.21 CBY32486.1 - 2.1e-73 247.6 0.0 3.4e-73 246.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY32486.1 - 6.8e-08 32.0 0.4 1.3e-07 31.1 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBY32486.1 - 0.00082 19.8 11.7 0.0028 18.1 11.7 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 CBY32486.1 - 4.8 7.3 9.2 3.9 7.6 6.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon WW PF00397.26 CBY32487.1 - 1.2e-09 38.1 0.0 1.5e-06 28.2 0.0 3.6 3 0 0 3 3 3 2 WW domain RRM_1 PF00076.22 CBY32488.1 - 1.4e-31 108.1 0.7 4.1e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOPS PF08075.11 CBY32488.1 - 9.3e-19 67.4 0.1 4.7e-18 65.1 0.1 2.3 1 0 0 1 1 1 1 NOPS (NUC059) domain RRM_occluded PF16842.5 CBY32488.1 - 1.2e-06 28.2 0.0 9.2e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CBY32488.1 - 1.4e-05 24.6 0.0 0.00027 20.5 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32488.1 - 4.3e-05 23.6 0.0 0.00058 19.9 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY32488.1 - 0.00048 20.1 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY32488.1 - 0.0083 16.2 8.8 0.29 11.2 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif FAM110_N PF14161.6 CBY32488.1 - 0.11 12.7 0.8 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Centrosome-associated N terminus Nucleoplasmin PF03066.15 CBY32489.1 - 1.7e-17 63.7 0.0 4.6e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain Nop53 PF07767.11 CBY32489.1 - 0.0024 17.4 19.8 0.0031 17.0 19.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Mif2_N PF15624.6 CBY32489.1 - 0.0042 17.8 5.6 0.0079 16.9 5.6 1.4 1 0 0 1 1 1 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CDC45 PF02724.14 CBY32489.1 - 1.9 6.7 9.9 2.4 6.4 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 CBY32489.1 - 3.4 7.6 21.5 6 6.8 21.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hid1 PF12722.7 CBY32489.1 - 5.7 4.9 8.0 6.9 4.7 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EF-hand_7 PF13499.6 CBY32490.1 - 2e-07 31.4 1.8 1.1e-05 25.8 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY32490.1 - 6.7e-06 25.3 0.0 0.02 14.4 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY32490.1 - 4.2e-05 23.1 1.0 0.27 11.3 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY32490.1 - 0.018 14.5 0.0 8 6.1 0.1 2.6 2 0 0 2 2 2 0 EF hand LicD PF04991.13 CBY32490.1 - 0.023 14.8 1.3 0.036 14.2 1.3 1.2 1 0 0 1 1 1 0 LicD family Arena_nucleocap PF00843.17 CBY32490.1 - 0.038 12.9 0.0 0.093 11.6 0.0 1.6 1 1 1 2 2 2 0 Arenavirus nucleocapsid N-terminal domain EF-hand_8 PF13833.6 CBY32490.1 - 0.13 12.1 2.2 0.17 11.8 0.1 2.3 3 0 0 3 3 3 0 EF-hand domain pair Ribosomal_L29e PF01779.17 CBY32491.1 - 0.028 14.8 0.7 0.093 13.1 0.8 2.0 1 1 0 1 1 1 0 Ribosomal L29e protein family Pkinase PF00069.25 CBY32492.1 - 1.2e-74 251.1 0.0 1.4e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32492.1 - 7.6e-36 123.7 0.0 2.3e-35 122.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY32492.1 - 1.3e-05 24.4 0.0 7e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY32492.1 - 8.6e-05 22.0 0.0 0.00033 20.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY32492.1 - 0.0019 18.2 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY32492.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RBFA PF02033.18 CBY32492.1 - 0.1 13.1 0.2 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribosome-binding factor A Kdo PF06293.14 CBY32492.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S4e PF00900.20 CBY32493.1 - 8e-34 115.4 0.1 1.8e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CBY32493.1 - 4.2e-22 77.5 0.1 6.6e-22 76.9 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CBY32493.1 - 1.6e-20 72.9 3.0 3.4e-20 71.9 3.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CBY32493.1 - 2.3e-08 33.6 0.0 5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CBY32493.1 - 0.00024 20.9 2.4 0.0004 20.2 0.0 2.7 3 0 0 3 3 3 1 KOW motif S4_2 PF13275.6 CBY32493.1 - 0.068 13.0 0.2 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 S4 domain Ribosomal_S28e PF01200.18 CBY32494.1 - 7e-34 115.6 0.4 7.7e-34 115.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Arm_vescicular PF18770.1 CBY32495.1 - 8.3e-06 25.7 0.0 0.0037 17.1 0.1 2.8 2 0 0 2 2 2 2 Armadillo tether-repeat of vescicular transport factor CENP-F_leu_zip PF10473.9 CBY32495.1 - 0.0032 17.5 13.3 0.0032 17.5 13.3 5.3 2 1 4 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TetR_C_27 PF17935.1 CBY32495.1 - 0.088 12.9 0.4 0.25 11.4 0.4 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sec5 PF15469.6 CBY32497.1 - 7.2e-38 130.3 1.3 7.2e-38 130.3 1.3 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 TIG PF01833.24 CBY32497.1 - 8.8e-10 38.5 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain GUN4_N PF16416.5 CBY32497.1 - 0.035 14.1 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal WD40_alt PF14077.6 CBY32498.1 - 0.0055 16.5 0.9 0.0055 16.5 0.9 2.3 2 0 0 2 2 2 1 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 CBY32498.1 - 0.0079 16.4 3.0 0.0079 16.4 3.0 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain DUF2443 PF10398.9 CBY32498.1 - 0.013 15.6 2.3 0.056 13.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) AAA_23 PF13476.6 CBY32498.1 - 1.2 9.5 8.1 2 8.8 8.1 1.6 1 1 0 1 1 1 0 AAA domain YvrJ PF12841.7 CBY32498.1 - 9.1 5.9 8.0 4.4 6.9 2.1 2.3 2 0 0 2 2 2 0 YvrJ protein family Myosin_tail_1 PF01576.19 CBY32499.1 - 0.0035 15.3 67.0 0.27 9.0 67.0 2.8 1 1 0 1 1 1 1 Myosin tail ZapB PF06005.12 CBY32499.1 - 0.023 15.1 8.5 0.023 15.1 8.5 8.3 3 2 5 8 8 8 0 Cell division protein ZapB GOLGA2L5 PF15070.6 CBY32500.1 - 2.5e-09 36.4 23.0 2.5e-09 36.4 23.0 2.0 1 1 1 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 Med9 PF07544.13 CBY32500.1 - 9.4e-05 22.4 3.7 9.4e-05 22.4 3.7 3.9 1 1 3 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 CBY32500.1 - 0.0067 15.8 14.3 0.0067 15.8 14.3 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 CBY32500.1 - 0.011 15.9 13.1 0.011 15.9 13.1 2.3 1 1 1 2 2 2 0 Tropomyosin like Fungal_TACC PF12709.7 CBY32500.1 - 0.027 14.9 1.3 0.027 14.9 1.3 3.7 1 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_DNA_bd PF12329.8 CBY32500.1 - 0.051 13.6 30.2 0.25 11.3 7.9 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 CBY32500.1 - 0.075 13.1 33.7 1.3 9.1 11.1 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 CBY32500.1 - 0.088 12.9 0.5 0.088 12.9 0.5 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation Tropomyosin PF00261.20 CBY32500.1 - 0.33 10.3 33.1 0.035 13.5 19.3 2.2 1 1 1 2 2 2 0 Tropomyosin ADIP PF11559.8 CBY32500.1 - 0.42 10.7 36.4 1.3 9.0 4.3 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DegS PF05384.11 CBY32500.1 - 1.1 8.7 25.3 0.19 11.2 1.5 3.2 1 1 2 3 3 3 0 Sensor protein DegS GvpK PF05121.12 CBY32500.1 - 1.2 9.2 15.0 0.65 10.1 1.1 3.4 1 1 2 4 4 4 0 Gas vesicle protein K Spc7 PF08317.11 CBY32500.1 - 1.8 7.4 34.5 0.24 10.3 14.8 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4164 PF13747.6 CBY32500.1 - 1.9 8.8 24.1 0.64 10.3 6.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Golgin_A5 PF09787.9 CBY32500.1 - 2 7.8 33.6 0.37 10.2 5.3 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CBY32500.1 - 2.1 8.4 17.8 10 6.1 4.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 CBY32500.1 - 2.9 8.6 26.3 1.1 9.9 2.7 3.2 1 1 1 3 3 3 0 Initiation control protein YabA Leu_zip PF15294.6 CBY32500.1 - 3.8 6.9 27.9 0.33 10.4 10.9 2.1 1 1 1 2 2 2 0 Leucine zipper HAP1_N PF04849.13 CBY32500.1 - 5.5 6.1 34.7 1.3 8.2 14.2 2.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FUSC PF04632.12 CBY32500.1 - 6.4 5.2 11.6 7.6 4.9 11.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 CBY32500.1 - 9.1 6.5 21.6 8.4 6.6 8.2 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GOLGA2L5 PF15070.6 CBY32501.1 - 3.4e-17 62.4 2.3 3.9e-17 62.2 2.3 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Macoilin PF09726.9 CBY32501.1 - 0.0032 16.1 3.2 0.0035 16.0 3.2 1.0 1 0 0 1 1 1 1 Macoilin family UPF0242 PF06785.11 CBY32501.1 - 0.032 14.3 7.8 0.052 13.7 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 CBY32501.1 - 0.28 11.4 11.0 0.99 9.6 1.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CBY32501.1 - 0.66 8.8 13.9 0.85 8.4 13.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cgr1 PF03879.14 CBY32501.1 - 0.81 10.1 5.6 3.5 8.1 5.6 1.9 1 1 0 1 1 1 0 Cgr1 family GIT_CC PF16559.5 CBY32501.1 - 0.82 9.6 9.6 0.11 12.4 1.5 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 CBY32501.1 - 1.3 9.6 14.0 0.23 12.0 1.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CBY32501.1 - 1.4 8.7 13.8 0.19 11.5 2.5 2.4 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 CBY32501.1 - 1.7 9.3 8.6 0.72 10.5 1.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Ax_dynein_light PF10211.9 CBY32501.1 - 3.5 7.5 12.0 0.62 10.0 5.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain HALZ PF02183.18 CBY32501.1 - 5.3 7.3 11.4 6.3 7.1 3.5 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper APG6_N PF17675.1 CBY32501.1 - 5.4 7.6 15.9 14 6.2 15.6 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 CBY32501.1 - 7 7.1 13.2 3.6 8.0 8.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) IQ PF00612.27 CBY32503.1 - 0.0016 18.1 1.0 0.0016 18.1 1.0 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif TBCC_N PF16752.5 CBY32503.1 - 2.1 8.8 7.9 12 6.4 2.9 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Ninjurin PF04923.12 CBY32504.1 - 1.5e-08 34.5 12.1 2.7e-07 30.5 12.1 2.2 1 1 0 1 1 1 1 Ninjurin HECT PF00632.25 CBY32505.1 - 5.7e-87 292.0 0.5 7.2e-87 291.7 0.5 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sushi PF00084.20 CBY32507.1 - 0.0014 19.2 0.2 0.0033 18.0 0.2 1.6 1 0 0 1 1 1 1 Sushi repeat (SCR repeat) RSS_P20 PF11757.8 CBY32509.1 - 0.49 10.9 7.2 0.22 12.0 3.6 2.2 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain LRR_4 PF12799.7 CBY32510.1 - 1.3e-13 50.9 25.2 2.9e-05 24.4 1.7 4.7 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY32510.1 - 1.9e-10 40.4 28.5 3.5e-05 23.5 8.0 4.9 3 1 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 CBY32510.1 - 0.0015 18.4 12.2 2.5 8.4 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CBY32510.1 - 0.0039 17.5 21.0 3.8 8.4 0.0 7.7 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 CBY32510.1 - 0.097 12.2 14.0 0.12 11.8 2.6 3.2 2 1 2 4 4 4 0 Leucine-rich repeat TMF_TATA_bd PF12325.8 CBY32510.1 - 0.11 12.7 6.9 1.4 9.1 3.7 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Haem_bd PF14376.6 CBY32511.1 - 0.091 12.7 2.4 0.3 11.0 2.4 1.9 1 0 0 1 1 1 0 Haem-binding domain EF-hand_1 PF00036.32 CBY32512.1 - 3.6e-15 54.3 3.0 3.2e-07 29.4 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY32512.1 - 5.1e-15 54.0 2.2 5.4e-06 25.9 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY32512.1 - 4.7e-13 48.0 2.1 2.7e-06 26.6 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY32512.1 - 7.5e-08 32.7 1.5 0.0069 16.8 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY32512.1 - 0.00035 20.4 3.7 0.2 11.5 0.1 3.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY32512.1 - 0.068 13.5 0.2 26 5.2 0.0 3.0 3 1 0 3 3 3 0 EF-hand domain Excalibur PF05901.11 CBY32512.1 - 0.12 13.0 1.7 4.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Excalibur calcium-binding domain Patched PF02460.18 CBY32513.1 - 1.1e-27 96.6 13.9 1.2e-27 96.4 13.9 1.0 1 0 0 1 1 1 1 Patched family ACR_tran PF00873.19 CBY32513.1 - 0.003 15.3 14.9 0.0038 15.0 14.9 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family NPC1_N PF16414.5 CBY32514.1 - 1.3e-74 250.9 12.0 1.9e-74 250.3 12.0 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CBY32514.1 - 4.7e-55 185.6 7.5 4.7e-55 185.6 7.5 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CBY32514.1 - 6e-47 160.3 5.6 9.6e-47 159.6 5.6 1.2 1 0 0 1 1 1 1 Patched family MMPL PF03176.15 CBY32514.1 - 6.3e-06 25.4 3.0 6.3e-06 25.4 3.0 2.0 3 0 0 3 3 3 1 MMPL family Zip PF02535.22 CBY32515.1 - 6.2e-43 147.3 11.0 8.1e-30 104.2 4.5 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter UPF0370 PF13980.6 CBY32515.1 - 0.1 12.7 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) UMPH-1 PF05822.12 CBY32518.1 - 6.7e-65 219.0 0.4 8.1e-65 218.8 0.4 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Erp_C PF06780.11 CBY32518.1 - 0.056 13.5 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus G-alpha PF00503.20 CBY32519.1 - 0.016 14.4 3.3 1.2 8.2 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Kelch_1 PF01344.25 CBY32521.1 - 3.3e-11 42.6 0.2 0.015 14.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CBY32521.1 - 4.5e-11 42.3 5.3 0.013 15.4 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CBY32521.1 - 2.5e-06 27.6 1.5 0.0067 16.7 0.0 3.7 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBY32521.1 - 3.1e-06 27.0 0.1 0.052 13.6 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY32521.1 - 5.9e-06 26.2 2.9 0.21 11.6 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Nop53 PF07767.11 CBY32522.1 - 1.6e-68 231.9 38.7 1.6e-68 231.9 38.7 1.9 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) zf-3CxxC_2 PF17180.4 CBY32523.1 - 4.2e-14 53.0 10.1 4.2e-14 53.0 10.1 5.5 4 3 3 7 7 7 1 Zinc-binding domain Spt20 PF12090.8 CBY32524.1 - 0.0063 16.2 1.2 0.0067 16.1 0.4 1.4 1 1 0 1 1 1 1 Spt20 family NPR3 PF03666.13 CBY32524.1 - 0.12 11.1 1.0 0.15 10.9 1.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Aldo_ket_red PF00248.21 CBY32525.1 - 1.2e-49 169.1 0.0 1.4e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Varsurf_PPLC PF03490.13 CBY32526.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C VWA PF00092.28 CBY32528.1 - 1.9e-29 103.1 0.1 3e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY32528.1 - 1.8e-11 44.6 0.0 4.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY32528.1 - 0.03 14.3 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_23 PF13476.6 CBY32528.1 - 0.095 13.2 6.6 0.14 12.6 6.6 1.3 1 0 0 1 1 1 0 AAA domain Nsp1_C PF05064.13 CBY32528.1 - 0.15 11.9 3.8 0.31 10.9 3.8 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region CUB PF00431.20 CBY32529.1 - 4.8e-14 52.6 6.8 1.9e-08 34.6 0.1 3.2 3 1 0 3 3 3 2 CUB domain SSP160 PF06933.11 CBY32529.1 - 3.1e-05 22.4 4.4 3.1e-05 22.4 4.4 2.0 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 G-gamma PF00631.22 CBY32530.1 - 2.9e-13 49.6 0.0 3.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF5103 PF17116.5 CBY32530.1 - 0.021 14.1 0.2 0.021 14.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) CarboxypepD_reg PF13620.6 CBY32532.1 - 2.2e-38 130.4 0.2 5.3e-07 29.8 0.2 8.6 9 0 0 9 9 9 6 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 CBY32532.1 - 2.2e-24 85.8 1.9 1.7e-05 25.0 0.1 7.4 7 1 1 8 8 8 4 SdrD B-like domain DUF2012 PF09430.10 CBY32532.1 - 2.5e-18 66.4 7.1 0.002 18.2 0.0 8.6 5 3 3 8 8 8 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 CBY32532.1 - 1.6e-13 50.4 8.9 0.0028 17.6 0.0 7.1 8 0 0 8 8 8 4 CarboxypepD_reg-like domain SpaA PF17802.1 CBY32532.1 - 1.1e-10 41.7 2.0 0.0096 16.2 0.0 6.3 6 1 1 7 7 6 2 Prealbumin-like fold domain TTR-52 PF01060.23 CBY32532.1 - 5.5e-05 23.8 0.2 14 6.5 0.0 5.4 6 0 0 6 6 5 1 Transthyretin-like family DUF1416 PF07210.12 CBY32532.1 - 6.3e-05 22.8 0.2 0.00098 19.0 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1416) DUF2846 PF11008.8 CBY32532.1 - 0.00028 20.8 2.1 0.23 11.5 0.0 5.4 7 0 0 7 7 7 1 Protein of unknown function (DUF2846) Y_Y_Y PF07495.13 CBY32532.1 - 0.0011 18.9 0.4 0.5 10.4 0.0 4.5 4 0 0 4 4 4 1 Y_Y_Y domain EMP24_GP25L PF01105.24 CBY32532.1 - 0.008 16.1 1.4 0.67 9.9 0.0 3.8 3 1 1 4 4 4 1 emp24/gp25L/p24 family/GOLD MetallophosN PF16371.5 CBY32532.1 - 0.0082 16.4 1.3 0.88 9.9 0.1 3.9 3 0 0 3 3 3 1 N terminal of Calcineurin-like phosphoesterase bMG3 PF11974.8 CBY32532.1 - 0.13 12.3 0.0 8.8 6.4 0.0 3.7 4 0 0 4 4 4 0 Bacterial alpha-2-macroglobulin MG3 domain MORN PF02493.20 CBY32533.1 - 7e-07 28.8 17.4 0.0015 18.3 1.0 5.0 5 1 0 5 5 5 3 MORN repeat Mak10 PF04112.13 CBY32534.1 - 4.8e-19 68.5 0.0 6.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mak10 PF04112.13 CBY32535.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TSP_1 PF00090.19 CBY32537.1 - 1.4e-11 44.4 39.3 3.6e-08 33.5 11.3 4.7 4 0 0 4 4 4 3 Thrombospondin type 1 domain CAP PF00188.26 CBY32537.1 - 5.5e-05 24.0 0.5 0.00091 20.1 0.5 2.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family cEGF PF12662.7 CBY32537.1 - 0.00024 21.0 4.6 0.00024 21.0 4.6 2.8 2 0 0 2 2 2 1 Complement Clr-like EGF-like CUB PF00431.20 CBY32537.1 - 0.12 12.7 2.0 0.19 12.1 0.1 2.4 2 0 0 2 2 2 0 CUB domain PQQ PF01011.21 CBY32539.1 - 0.0011 18.8 1.5 0.0046 16.8 0.4 2.5 1 1 1 2 2 2 1 PQQ enzyme repeat DUF3139 PF11337.8 CBY32539.1 - 0.02 15.5 1.5 0.027 15.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Clp1 PF06807.14 CBY32539.1 - 0.14 12.6 0.1 0.24 11.8 0.1 1.3 1 1 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 BCD PF15461.6 CBY32541.1 - 0.001 18.6 1.2 0.0017 17.9 1.0 1.5 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase PIG-Y PF15159.6 CBY32541.1 - 1.3 10.0 7.1 4.6 8.2 7.1 1.9 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HLH PF00010.26 CBY32543.1 - 3.1e-13 49.5 3.1 3.1e-13 49.5 3.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAGE PF01454.19 CBY32543.1 - 0.069 12.8 0.2 0.069 12.8 0.2 1.5 2 0 0 2 2 2 0 MAGE family PDEase_I PF00233.19 CBY32544.1 - 4.4e-72 242.7 2.1 6.4e-72 242.1 2.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.25 CBY32546.1 - 3.5e-37 128.2 0.0 3.3e-28 98.8 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32546.1 - 3.4e-19 69.1 0.0 3.2e-16 59.4 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY32546.1 - 0.016 14.5 0.3 2.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 CBY32546.1 - 0.024 14.0 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bap31_Bap29_C PF18035.1 CBY32546.1 - 0.65 10.0 4.9 0.12 12.4 0.9 1.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RRM_1 PF00076.22 CBY32547.1 - 1.1e-41 140.5 0.0 2e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32547.1 - 2.2e-06 27.7 0.0 0.009 16.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CBY32547.1 - 2e-05 24.2 0.0 0.0051 16.4 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBY32547.1 - 0.019 14.6 0.3 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 CBY32547.1 - 0.041 13.9 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Peptidase_C48 PF02902.19 CBY32548.1 - 1.1e-18 67.9 0.5 2.1e-17 63.7 0.5 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_1 PF00076.22 CBY32549.1 - 1e-15 57.3 0.0 1.2e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 CBY32549.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 OCRE domain EF-hand_7 PF13499.6 CBY32550.1 - 2.1e-11 44.1 2.0 2.1e-11 44.1 2.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY32550.1 - 6.7e-11 40.9 12.6 6e-07 28.6 1.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY32550.1 - 1.9e-10 39.8 4.6 5.3e-05 22.8 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY32550.1 - 8.3e-09 35.2 1.1 0.0004 20.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY32550.1 - 5.6e-07 28.8 13.0 0.0013 18.1 1.0 3.2 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CBY32550.1 - 4.1e-05 23.9 0.2 4.1e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY32550.1 - 0.15 12.0 1.1 0.96 9.3 0.2 2.1 1 1 1 2 2 2 0 Caleosin related protein Snf7 PF03357.21 CBY32551.1 - 2.4e-31 108.7 23.8 2.4e-31 108.7 23.8 1.9 1 1 1 2 2 2 1 Snf7 POR PF01558.18 CBY32551.1 - 0.23 11.5 2.4 0.14 12.2 0.6 1.6 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase YlqD PF11068.8 CBY32551.1 - 1.1 9.6 16.2 0.23 11.8 10.2 2.2 1 1 1 2 2 2 0 YlqD protein DUF2855 PF11017.8 CBY32551.1 - 1.3 8.7 4.1 10 5.8 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) Prefoldin_2 PF01920.20 CBY32551.1 - 7.5 6.6 16.2 0.41 10.6 2.2 3.2 2 1 1 3 3 3 0 Prefoldin subunit Apt1 PF10351.9 CBY32552.1 - 1.1 8.0 16.3 1.2 7.9 16.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3807 PF12720.7 CBY32552.1 - 1.5 9.1 15.4 1.7 8.9 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 CBY32552.1 - 1.9 8.2 9.5 2.3 8.0 9.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CBY32552.1 - 4.9 5.8 11.7 5.1 5.7 11.7 1.0 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 CBY32552.1 - 6.4 6.6 19.8 7 6.5 19.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 CBY32552.1 - 7.4 4.7 15.8 7.5 4.7 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CTD_bind PF04818.13 CBY32553.1 - 3.4e-06 27.8 1.5 7.4e-06 26.7 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 CBY32553.1 - 0.021 15.3 0.5 0.021 15.3 0.5 4.3 4 0 0 4 4 4 0 Subunit of cleavage factor IA Pcf11 zf_UBZ PF18439.1 CBY32553.1 - 0.07 12.7 0.8 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 CBY32553.1 - 0.22 12.0 1.7 20 5.7 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 CBY32553.1 - 2.7 8.0 4.4 32 4.5 1.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pox_VLTF3 PF04947.14 CBY32554.1 - 0.089 12.5 7.0 0.24 11.1 2.8 2.3 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Q_salvage PF10343.9 CBY32554.1 - 0.19 11.3 3.8 0.23 11.0 0.3 1.9 1 1 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Tam41_Mmp37 PF09139.11 CBY32554.1 - 0.31 10.5 4.5 0.22 10.9 2.5 1.6 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial Myb_DNA-binding PF00249.31 CBY32555.1 - 0.014 15.6 0.1 0.068 13.4 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY32555.1 - 0.041 13.8 1.0 0.13 12.2 1.0 1.9 1 0 0 1 1 1 0 Myb DNA-binding like DUF2894 PF11445.8 CBY32555.1 - 0.22 12.0 3.0 0.4 11.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) HlyIII PF03006.20 CBY32557.1 - 2e-69 233.7 21.2 2.4e-69 233.5 21.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related L51_S25_CI-B8 PF05047.16 CBY32558.1 - 5.9e-15 54.9 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.11 CBY32558.1 - 0.081 13.3 0.0 0.49 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) Rep_N PF08724.10 CBY32558.1 - 0.2 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Rep protein catalytic domain like DSPc PF00782.20 CBY32559.1 - 7.5e-35 119.6 0.8 1.7e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 CBY32559.1 - 2.2e-07 30.7 1.2 5.8e-07 29.3 1.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 CBY32559.1 - 0.0057 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FN3_7 PF18447.1 CBY32560.1 - 0.37 11.1 4.1 1.1 9.6 0.2 2.5 1 1 0 2 2 2 0 Fibronectin type III domain EGF_CA PF07645.15 CBY32561.1 - 3.1e-117 382.5 261.4 1.1e-09 38.4 4.6 16.2 16 0 0 16 16 16 16 Calcium-binding EGF domain cEGF PF12662.7 CBY32561.1 - 5.6e-55 182.8 138.3 1.2e-05 25.2 1.8 17.1 16 0 0 16 16 16 15 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY32561.1 - 9e-47 157.0 202.2 5.7e-09 36.0 6.3 17.3 15 2 0 16 16 16 14 EGF domain EGF PF00008.27 CBY32561.1 - 2.3e-26 91.7 173.1 4.6e-05 23.6 3.3 17.3 16 1 0 16 16 16 14 EGF-like domain FXa_inhibition PF14670.6 CBY32561.1 - 3.1e-19 68.9 196.1 6e-05 23.2 5.0 16.7 13 3 3 16 16 16 12 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY32561.1 - 1.8e-18 66.4 174.5 0.00021 21.8 4.3 19.9 21 0 0 21 21 21 11 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY32561.1 - 2.9e-11 43.2 50.3 1.1e-05 25.3 5.4 15.8 15 1 0 15 15 15 9 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY32561.1 - 9.8e-06 25.8 42.5 8.1e-05 22.9 10.7 16.1 14 2 2 16 16 16 8 Pvs28 EGF domain Thioredoxin PF00085.20 CBY32562.1 - 6.2e-52 173.9 1.4 4.2e-25 87.7 0.2 2.1 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 CBY32562.1 - 1.5e-09 37.8 0.2 0.00094 19.1 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 CBY32562.1 - 1.7e-09 38.1 2.8 0.00046 20.6 0.1 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY32562.1 - 5.6e-09 36.2 0.2 0.024 15.0 0.0 3.6 2 2 1 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY32562.1 - 1.1e-06 28.8 0.2 0.0087 16.2 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_4 PF13462.6 CBY32562.1 - 5e-05 23.5 0.3 0.24 11.5 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.6 CBY32562.1 - 6.4e-05 22.9 0.2 0.044 13.8 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.10 CBY32562.1 - 0.00014 21.6 0.1 0.038 13.7 0.0 2.2 2 0 0 2 2 2 2 Redoxin OST3_OST6 PF04756.13 CBY32562.1 - 0.032 13.6 0.1 0.29 10.5 0.0 2.0 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family TraF PF13728.6 CBY32562.1 - 0.039 13.8 0.0 1.5 8.6 0.0 2.5 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBY32562.1 - 0.076 12.8 0.4 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 CBY32562.1 - 0.1 12.8 5.8 7.1 6.9 0.5 3.2 2 2 0 2 2 2 0 Glutaredoxin Exo_endo_phos_2 PF14529.6 CBY32563.1 - 0.001 18.9 1.6 0.0045 16.8 0.0 2.9 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase CdiA_C PF18451.1 CBY32563.1 - 0.17 12.1 1.8 1.1 9.5 0.5 3.1 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain L1R_F9L PF02442.17 CBY32563.1 - 0.74 9.6 6.2 0.45 10.3 1.0 2.6 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses UBA2_C PF16195.5 CBY32567.1 - 0.061 14.0 0.2 0.093 13.4 0.2 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Voltage_CLC PF00654.20 CBY32569.1 - 6.9e-90 301.8 23.1 4e-89 299.3 21.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY32569.1 - 7.3e-12 45.5 0.1 7.1e-07 29.6 0.2 2.7 2 0 0 2 2 2 2 CBS domain Tub PF01167.18 CBY32570.1 - 8e-77 258.2 0.3 1.2e-76 257.6 0.3 1.3 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CBY32570.1 - 3.7 7.0 6.7 0.93 9.0 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3527) AMP-binding PF00501.28 CBY32571.1 - 4.6e-86 289.1 0.0 5.7e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY32571.1 - 6.5e-12 46.3 0.0 1.9e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CBY32571.1 - 0.047 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CBY32572.1 - 1.7e-81 274.0 0.3 1.8e-48 165.2 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme E2_bind PF08825.10 CBY32572.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 E2 binding domain AA_permease_2 PF13520.6 CBY32573.1 - 7.3e-32 110.7 20.6 8.9e-32 110.4 20.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY32573.1 - 2.7e-17 62.5 18.1 3.6e-17 62.1 18.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CBY32574.1 - 5.6e-11 41.9 8.2 6.6e-11 41.7 8.2 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CBY32574.1 - 0.0016 17.5 7.9 0.0019 17.3 7.4 1.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease PF00324.21 CBY32574.1 - 0.0067 15.1 7.8 0.008 14.8 7.8 1.1 1 0 0 1 1 1 1 Amino acid permease ABC2_membrane PF01061.24 CBY32575.1 - 3.1e-43 147.6 26.6 3.1e-43 147.6 26.6 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBY32575.1 - 3.5e-29 102.1 0.1 5.3e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY32575.1 - 3.6e-10 40.1 0.0 4.8e-05 23.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY32575.1 - 2.2e-08 33.8 0.3 1.8e-07 30.9 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY32575.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CBY32575.1 - 0.00049 19.3 20.0 0.00086 18.5 20.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 CBY32575.1 - 0.00091 19.2 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 CBY32575.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CBY32575.1 - 0.0049 16.6 0.3 0.011 15.4 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY32575.1 - 0.0057 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CBY32575.1 - 0.029 14.9 0.3 0.073 13.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY32575.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 CBY32575.1 - 0.035 14.4 0.7 0.21 11.8 0.7 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY32575.1 - 0.04 13.5 0.2 0.074 12.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY32575.1 - 0.074 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 CBY32575.1 - 0.39 9.3 0.0 0.39 9.3 0.0 2.1 3 0 0 3 3 3 0 AAA domain ASH PF15780.5 CBY32576.1 - 1.6e-06 28.2 4.0 3.5e-05 23.9 0.1 4.1 4 0 0 4 4 4 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBY32577.1 - 5.7e-05 23.3 0.0 0.0057 16.9 0.0 2.8 2 0 0 2 2 2 1 Transmembrane protein 131-like ASH PF15780.5 CBY32577.1 - 0.00084 19.5 0.1 3.9 7.8 0.0 3.4 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY32577.1 - 0.0017 18.4 0.0 0.52 10.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1573) UCMA PF17085.5 CBY32577.1 - 0.19 11.7 5.4 0.6 10.1 5.4 1.8 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Kinesin PF00225.23 CBY32578.1 - 8.5e-36 123.5 1.9 5.6e-35 120.8 1.9 2.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY32578.1 - 1.1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding MAPEG PF01124.18 CBY32579.1 - 2.7e-26 92.0 0.1 3.1e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 MAPEG family rRNA_proc-arch PF13234.6 CBY32580.1 - 5.2e-74 249.6 1.8 8.4e-74 248.9 0.3 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CBY32580.1 - 1.3e-53 181.0 1.3 3e-53 179.8 1.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Helicase_C PF00271.31 CBY32580.1 - 3.2e-06 27.5 0.3 1.2e-05 25.7 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CENP-F_leu_zip PF10473.9 CBY32580.1 - 0.034 14.2 5.8 3.1 7.8 0.0 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HTH_43 PF09904.9 CBY32580.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix Cytochrom_C PF00034.21 CBY32581.1 - 3.4e-10 40.9 0.0 4.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBY32581.1 - 8.9e-05 22.7 2.2 0.00017 21.9 2.2 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CBY32581.1 - 0.0065 16.2 0.3 0.01 15.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 CBY32581.1 - 0.12 12.8 0.3 18 5.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome P460 GAD-like PF08887.11 CBY32581.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain DEAD PF00270.29 CBY32582.1 - 1.3e-16 60.9 0.0 2.5e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY32582.1 - 0.0044 17.3 0.0 0.046 14.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 CBY32582.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pyr_redox_2 PF07992.14 CBY32583.1 - 1e-09 38.1 0.0 1.5e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY32583.1 - 4.6e-07 30.0 0.2 9.5e-07 29.0 0.0 1.6 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CBY32583.1 - 1.1e-05 25.4 0.1 5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBY32583.1 - 0.00028 21.4 2.9 1 9.9 0.0 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY32583.1 - 0.0054 16.0 1.4 0.14 11.3 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBY32583.1 - 0.0059 15.9 0.1 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 CBY32583.1 - 0.034 13.0 0.0 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.17 CBY32583.1 - 0.045 14.3 0.1 9.7 6.9 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 CBY32583.1 - 0.052 12.3 0.0 0.097 11.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 CBY32583.1 - 0.059 13.8 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CBY32583.1 - 0.088 12.0 0.8 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 CBY32583.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2540 PF10802.8 CBY32583.1 - 1.4 9.0 6.9 4.4 7.5 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2540) Kinesin PF00225.23 CBY32587.1 - 8.9e-87 291.1 0.0 8.9e-87 291.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain MKLP1_Arf_bdg PF16540.5 CBY32587.1 - 2.2e-29 101.7 1.4 5.3e-29 100.4 0.1 2.2 2 0 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Microtub_bd PF16796.5 CBY32587.1 - 2.1e-20 73.2 0.0 7.7e-20 71.4 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding ERM PF00769.19 CBY32587.1 - 0.00052 19.9 18.4 0.00052 19.9 18.4 2.7 3 0 0 3 3 3 1 Ezrin/radixin/moesin family KELK PF15796.5 CBY32588.1 - 0.0074 16.7 2.6 0.0074 16.7 2.6 3.2 2 1 1 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ank_2 PF12796.7 CBY32588.1 - 0.02 15.5 0.1 3.1 8.4 0.1 2.5 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32588.1 - 0.036 14.4 0.0 0.48 10.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) LMBR1 PF04791.16 CBY32588.1 - 0.31 9.9 11.0 0.42 9.5 11.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 CBY32588.1 - 1.2 8.6 11.6 1.7 8.1 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 CBY32588.1 - 1.9 8.9 29.9 3 8.2 17.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF745 PF05335.13 CBY32588.1 - 8.6 6.0 18.7 2.6 7.8 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) zf-H2C2_2 PF13465.6 CBY32589.1 - 4.8e-48 159.5 54.2 4.6e-08 33.1 1.8 8.5 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 CBY32589.1 - 1.8e-37 125.7 64.5 4.9e-06 26.7 0.6 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY32589.1 - 1.8e-29 99.9 59.8 0.00061 20.4 0.4 8.5 8 0 0 8 8 8 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY32589.1 - 9.6e-16 57.6 31.9 0.002 18.4 0.1 8.2 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY32589.1 - 3.6e-15 55.8 45.7 0.00013 22.2 0.1 7.6 8 0 0 8 8 7 6 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY32589.1 - 2.9e-09 36.7 62.2 0.0093 15.9 0.8 9.5 9 0 0 9 9 9 5 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 CBY32589.1 - 1.8e-05 25.4 20.0 0.054 14.2 0.1 4.3 2 1 1 4 4 4 3 zinc-ribbon family zf-C2H2_11 PF16622.5 CBY32589.1 - 0.00017 21.3 44.4 0.034 13.9 1.0 7.8 8 0 0 8 8 8 4 zinc-finger C2H2-type zf_UBZ PF18439.1 CBY32589.1 - 0.00093 18.7 31.9 0.076 12.6 0.0 7.8 8 0 0 8 8 8 3 Ubiquitin-Binding Zinc Finger Scramblase PF03803.15 CBY32589.1 - 0.0024 17.2 3.9 0.68 9.2 0.1 2.2 1 1 1 2 2 2 2 Scramblase Zn-ribbon_8 PF09723.10 CBY32589.1 - 0.008 16.3 33.6 7.2 6.8 3.5 6.7 2 1 6 8 8 8 2 Zinc ribbon domain DUF3268 PF11672.8 CBY32589.1 - 0.016 15.5 16.2 0.12 12.7 0.6 3.8 2 1 1 4 4 4 0 zinc-finger-containing domain Elf1 PF05129.13 CBY32589.1 - 0.041 13.9 1.0 0.041 13.9 1.0 5.0 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like HypA PF01155.19 CBY32589.1 - 0.11 12.5 22.6 2.9 7.9 1.4 4.3 1 1 4 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADK_lid PF05191.14 CBY32589.1 - 0.14 12.1 16.6 1.1 9.3 0.0 5.1 3 1 2 5 5 5 0 Adenylate kinase, active site lid zf-Paramyx-P PF13008.7 CBY32589.1 - 1.5 8.3 19.5 9.2 5.8 0.3 6.1 6 0 0 6 6 6 0 Zinc-binding domain of Paramyxoviridae V protein RNA_POL_M_15KD PF02150.16 CBY32589.1 - 2.1 8.3 12.3 24 4.9 0.1 5.3 5 1 1 6 6 6 0 RNA polymerases M/15 Kd subunit BolA PF01722.18 CBY32589.1 - 3.1 8.1 6.4 10 6.5 0.3 3.1 3 1 0 3 3 3 0 BolA-like protein OSTMP1 PF09777.9 CBY32589.1 - 4.8 6.5 9.8 9.4 5.6 2.3 2.2 1 1 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-AN1 PF01428.16 CBY32589.1 - 8.2 6.7 41.4 21 5.4 0.5 7.9 5 2 3 8 8 8 0 AN1-like Zinc finger DUF2964 PF11177.8 CBY32590.1 - 0.11 12.7 1.5 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Trypsin PF00089.26 CBY32591.1 - 4e-62 209.9 1.1 6.2e-62 209.3 1.1 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY32591.1 - 0.039 14.3 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) DNA_pol_B_exo1 PF03104.19 CBY32592.1 - 5.2e-72 242.8 0.4 5.2e-72 242.8 0.4 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 CBY32592.1 - 1.3e-07 31.6 0.2 4.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CBY32592.1 - 5.9e-06 26.4 0.1 3.3e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 RNase_H superfamily SH2 PF00017.24 CBY32595.1 - 9.3e-14 51.3 0.3 1.6e-13 50.5 0.3 1.4 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY32595.1 - 9.2e-12 44.4 0.0 1e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY32595.1 - 2.4e-05 24.1 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY32595.1 - 3.2e-05 23.5 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain EGF_CA PF07645.15 CBY32597.1 - 5.1e-28 97.0 47.1 1.9e-11 44.0 6.6 4.4 3 1 1 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY32597.1 - 2.5e-17 62.7 42.1 1.4e-06 28.3 7.1 4.4 4 0 0 4 4 4 3 EGF domain EGF PF00008.27 CBY32597.1 - 5.6e-14 52.1 38.5 0.00058 20.1 3.4 4.5 4 0 0 4 4 4 4 EGF-like domain fn3 PF00041.21 CBY32597.1 - 3.4e-10 40.1 0.1 3.7e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain SEA PF01390.20 CBY32597.1 - 2.7e-08 33.8 5.8 0.0073 16.4 0.1 3.7 3 0 0 3 3 3 3 SEA domain EGF_MSP1_1 PF12946.7 CBY32597.1 - 3.2e-06 27.1 26.3 0.00097 19.1 4.2 3.8 3 0 0 3 3 3 2 MSP1 EGF domain 1 hEGF PF12661.7 CBY32597.1 - 6.7e-06 26.5 33.5 0.00074 20.1 3.6 4.5 4 0 0 4 4 4 3 Human growth factor-like EGF cEGF PF12662.7 CBY32597.1 - 4.7e-05 23.2 13.6 0.0013 18.6 2.6 3.4 3 0 0 3 3 3 2 Complement Clr-like EGF-like Comm PF15957.5 CBY32597.1 - 0.0055 17.0 0.7 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Commissureless FXa_inhibition PF14670.6 CBY32597.1 - 0.011 15.9 3.9 0.011 15.9 3.9 4.8 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site Phage_Gp23 PF10669.9 CBY32597.1 - 0.028 14.8 0.5 0.08 13.3 0.5 1.8 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) O-antigen_lig PF13425.6 CBY32597.1 - 0.14 10.9 0.0 0.3 9.8 0.0 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein LMBR1 PF04791.16 CBY32597.1 - 0.43 9.4 2.1 0.73 8.7 2.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein EF-hand_6 PF13405.6 CBY32599.1 - 8.5e-09 34.7 2.6 0.0023 17.7 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY32599.1 - 3.1e-08 34.0 0.4 0.0064 16.9 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY32599.1 - 1.9e-07 30.2 0.7 0.0037 16.7 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 CBY32599.1 - 0.00035 19.9 1.1 0.22 11.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY32599.1 - 0.0068 16.2 1.2 2.5 8.0 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain pair DUF4220 PF13968.6 CBY32600.1 - 0.0043 16.5 2.0 0.0043 16.5 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4220) Orf78 PF06024.12 CBY32600.1 - 0.31 11.4 2.6 3.3 8.1 0.3 3.1 3 0 0 3 3 3 0 Orf78 (ac78) zf-RING_5 PF14634.6 CBY32601.1 - 1.7e-08 34.2 13.8 3.4e-08 33.3 13.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY32601.1 - 0.0017 18.2 13.3 0.0093 15.8 13.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY32601.1 - 0.0022 18.3 14.1 0.0022 18.3 14.1 1.9 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY32601.1 - 0.011 15.7 10.9 0.08 13.0 4.7 2.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY32601.1 - 0.049 13.5 14.3 0.85 9.5 11.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MIEAP PF16026.5 CBY32601.1 - 0.14 12.4 2.0 0.16 12.2 2.0 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein zf-RING_6 PF14835.6 CBY32601.1 - 0.57 10.1 9.7 2 8.4 9.8 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CID_GANP PF16766.5 CBY32601.1 - 1.9 8.7 11.4 0.65 10.2 0.4 2.4 1 1 1 2 2 2 0 Binding region of GANP to ENY2 ATG16 PF08614.11 CBY32602.1 - 4.9e-06 26.9 97.5 0.089 13.0 21.4 5.2 2 1 3 5 5 5 4 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 CBY32602.1 - 0.0016 18.8 21.6 0.0016 18.8 21.6 4.4 2 1 3 5 5 5 1 Bacterial type III secretion protein (HrpB7) Golgin_A5 PF09787.9 CBY32602.1 - 0.034 13.6 91.3 0.011 15.3 21.1 3.8 1 1 2 3 3 3 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 CBY32602.1 - 0.23 11.0 74.7 0.48 10.0 10.9 4.2 2 2 2 4 4 4 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 CBY32602.1 - 0.73 8.7 86.6 0.37 9.6 15.3 4.5 1 1 3 4 4 4 0 Spc7 kinetochore protein KASH_CCD PF14662.6 CBY32602.1 - 2.2 8.1 87.4 1 9.1 22.2 5.2 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 CBY32602.1 - 4.9 6.9 99.1 11 5.8 14.4 4.6 1 1 4 5 5 5 0 Ezrin/radixin/moesin family YabA PF06156.13 CBY32602.1 - 5.8 7.6 72.0 0.12 13.0 6.5 7.3 1 1 5 7 7 7 0 Initiation control protein YabA APG6_N PF17675.1 CBY32602.1 - 5.8 7.4 97.9 0.45 11.0 13.9 5.2 2 1 2 5 5 5 0 Apg6 coiled-coil region ABC_tran PF00005.27 CBY32603.1 - 1.6e-48 164.7 0.1 5.1e-27 95.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY32603.1 - 1.7e-45 155.6 44.6 2.9e-34 118.7 12.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY32603.1 - 7.8e-21 75.2 0.0 1.4e-09 38.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBY32603.1 - 7.2e-06 26.6 1.2 0.0096 16.6 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) ABC2_membrane_2 PF12679.7 CBY32603.1 - 0.0004 19.8 5.0 0.0004 19.8 5.0 2.4 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 CBY32603.1 - 0.00044 19.7 0.0 2.7 7.4 0.0 4.1 4 2 1 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBY32603.1 - 0.077 13.5 0.3 0.077 13.5 0.3 3.3 4 1 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 CBY32603.1 - 0.078 12.9 0.2 0.23 11.3 0.2 1.8 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 CBY32603.1 - 0.084 12.5 0.1 0.22 11.1 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 CBY32603.1 - 0.21 11.2 13.1 0.97 9.1 0.0 4.3 5 0 0 5 5 5 0 AAA ATPase domain ARID PF01388.21 CBY32604.1 - 3.2e-07 30.9 0.0 9.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 CBY32604.1 - 0.034 14.8 0.0 0.17 12.6 0.0 2.0 2 0 0 2 2 2 0 RFX DNA-binding domain SIL1 PF16782.5 CBY32604.1 - 0.042 13.1 0.4 0.084 12.1 0.4 1.4 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 TPR_19 PF14559.6 CBY32605.1 - 0.00054 20.4 0.2 0.0055 17.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat RDD PF06271.12 CBY32606.1 - 1.8e-08 34.7 6.1 9.9e-08 32.3 6.1 1.9 1 1 0 1 1 1 1 RDD family DUF4765 PF15962.5 CBY32606.1 - 0.0068 14.4 0.1 0.0082 14.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4765) Mononeg_RNA_pol PF00946.19 CBY32606.1 - 0.023 12.4 1.5 0.031 12.0 1.5 1.1 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase Cadherin PF00028.17 CBY32607.1 - 2.2e-64 213.9 8.9 3.3e-16 59.5 0.1 6.4 6 0 0 6 6 6 6 Cadherin domain Cadherin_2 PF08266.12 CBY32607.1 - 5.4e-23 80.6 3.6 3.1e-17 62.2 0.0 5.2 5 0 0 5 5 5 3 Cadherin-like TMEM154 PF15102.6 CBY32607.1 - 0.0057 16.6 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family Cadherin_pro PF08758.11 CBY32607.1 - 0.027 14.6 0.4 3.7 7.8 0.1 2.9 3 0 0 3 3 3 0 Cadherin prodomain like DUF5001 PF16392.5 CBY32607.1 - 0.072 13.0 0.6 0.27 11.2 0.6 2.0 1 0 0 1 1 1 0 Ig-like domain EphA2_TM PF14575.6 CBY32607.1 - 0.096 13.6 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Trypsin PF00089.26 CBY32608.1 - 3.1e-119 396.6 13.3 4.1e-70 236.0 0.1 4.5 3 1 1 4 4 4 4 Trypsin CUB PF00431.20 CBY32608.1 - 1.2e-20 73.9 0.1 6.9e-11 42.5 0.0 2.7 2 0 0 2 2 2 2 CUB domain Trypsin_2 PF13365.6 CBY32608.1 - 1.1e-10 42.6 0.9 0.00021 22.2 0.0 4.7 4 0 0 4 4 4 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY32608.1 - 2.2e-10 40.9 2.2 3.6e-06 27.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1986) Dicty_REP PF05086.12 CBY32608.1 - 0.0087 14.1 2.8 0.013 13.5 2.8 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Peptidase_S6 PF02395.16 CBY32608.1 - 0.023 12.8 0.3 2 6.3 0.1 2.1 2 0 0 2 2 2 0 Immunoglobulin A1 protease Mucin PF01456.17 CBY32608.1 - 0.03 14.3 11.4 0.1 12.6 11.4 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY32608.1 - 0.43 10.6 7.3 1.4 8.9 7.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CBY32608.1 - 3.7 5.6 12.8 7.8 4.6 12.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Homeodomain PF00046.29 CBY32609.1 - 1.9e-22 78.9 10.0 3.1e-22 78.2 10.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY32609.1 - 0.025 14.5 1.4 0.062 13.2 1.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF641 PF04859.12 CBY32611.1 - 0.78 10.1 2.9 1.4 9.3 2.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) G-gamma PF00631.22 CBY32612.1 - 2.1e-06 27.6 0.0 2.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain CAP PF00188.26 CBY32613.1 - 6.1e-12 46.5 3.2 1.2e-11 45.5 3.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CRF-BP PF05428.11 CBY32613.1 - 0.078 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Kelch_2 PF07646.15 CBY32614.1 - 0.022 14.7 0.0 6.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Kelch motif PFU PF09070.11 CBY32614.1 - 0.044 14.0 0.7 0.5 10.6 0.3 2.1 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) SecY PF00344.20 CBY32616.1 - 9.4e-75 251.7 10.8 1.2e-74 251.3 10.8 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBY32616.1 - 1.3e-17 63.3 0.2 4.3e-17 61.7 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Zip PF02535.22 CBY32617.1 - 1.9e-33 116.1 7.2 2.3e-33 115.8 7.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RRM_1 PF00076.22 CBY32617.1 - 6.2e-12 45.2 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32617.1 - 8.6e-05 22.6 0.0 0.00024 21.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif DUF21 PF01595.20 CBY32617.1 - 0.038 13.7 2.8 0.062 13.0 2.8 1.5 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF1368 PF07112.11 CBY32618.1 - 0.022 13.6 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) RRM_1 PF00076.22 CBY32620.1 - 1.6e-26 91.9 0.1 1.8e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32620.1 - 5.7e-10 39.2 0.1 0.00066 19.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY32620.1 - 0.075 13.1 2.0 0.41 10.7 0.1 2.5 3 0 0 3 3 3 0 RNA binding motif 7tm_6 PF02949.20 CBY32621.1 - 0.43 9.6 10.7 0.28 10.2 4.1 2.1 1 1 1 2 2 2 0 7tm Odorant receptor Enolase_C PF00113.22 CBY32622.1 - 0.038 13.2 1.8 0.041 13.1 1.8 1.0 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Trypsin PF00089.26 CBY32623.1 - 1.4e-33 116.6 1.4 2.3e-33 115.9 1.4 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY32623.1 - 3.2e-06 28.1 0.0 6.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PHF5 PF03660.14 CBY32623.1 - 1.4 9.2 9.3 0.37 11.0 5.2 2.1 2 0 0 2 2 2 0 PHF5-like protein MGC-24 PF05283.11 CBY32625.1 - 0.0021 18.5 0.0 0.0022 18.4 0.0 1.1 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.6 CBY32625.1 - 0.0054 16.8 0.0 0.0069 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Trypan_PARP PF05887.11 CBY32625.1 - 0.02 14.9 20.0 0.042 13.8 20.0 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4064 PF13273.6 CBY32625.1 - 0.031 14.5 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF202 PF02656.15 CBY32625.1 - 0.048 14.1 0.0 0.067 13.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MnhB PF04039.13 CBY32625.1 - 0.07 13.5 0.9 0.07 13.5 0.9 1.5 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter SDA1 PF05285.12 CBY32625.1 - 2 7.8 7.6 2.8 7.3 7.6 1.2 1 0 0 1 1 1 0 SDA1 Connexin PF00029.19 CBY32627.1 - 6.8e-38 130.7 1.3 9.1e-38 130.3 1.3 1.1 1 0 0 1 1 1 1 Connexin DUF1461 PF07314.11 CBY32627.1 - 0.0047 16.9 3.0 0.007 16.3 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1461) Peptidase_M56 PF05569.11 CBY32627.1 - 0.015 14.5 1.8 0.044 13.0 0.2 2.1 2 1 0 2 2 2 0 BlaR1 peptidase M56 E2 PF08199.11 CBY32629.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage E2-like protein Sulfotransfer_1 PF00685.27 CBY32630.1 - 2.9e-12 46.6 0.0 3.8e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY32630.1 - 2.6e-06 28.0 0.0 3.2e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY32631.1 - 0.0017 17.9 1.7 0.0087 15.6 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY32631.1 - 0.0036 17.7 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase family Nucleoside_tran PF01733.18 CBY32631.1 - 0.03 13.7 0.5 0.043 13.2 0.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF4446 PF14584.6 CBY32631.1 - 0.069 13.1 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) zf-LITAF-like PF10601.9 CBY32631.1 - 0.27 11.5 2.2 12 6.3 1.3 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DcuC PF03606.15 CBY32631.1 - 0.28 9.6 0.3 0.44 8.9 0.3 1.3 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier VWD PF00094.25 CBY32632.1 - 1.9e-74 249.2 8.9 3.5e-27 95.6 0.9 4.1 3 1 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 CBY32632.1 - 1.9e-40 137.1 39.2 2.6e-18 66.2 10.9 7.9 7 1 1 8 8 8 3 C8 domain TIL PF01826.17 CBY32632.1 - 1.7e-23 82.6 84.4 1.3e-10 41.4 18.4 13.6 13 2 2 15 15 15 4 Trypsin Inhibitor like cysteine rich domain Mucin2_WxxW PF13330.6 CBY32632.1 - 1.2e-17 64.5 1.9 1.2e-17 64.5 1.9 4.6 3 0 0 3 3 3 1 Mucin-2 protein WxxW repeating region Pacifastin_I PF05375.13 CBY32632.1 - 0.00014 21.5 10.6 0.00014 21.5 10.6 7.8 8 0 0 8 8 8 2 Pacifastin inhibitor (LCMII) Trypan_PARP PF05887.11 CBY32633.1 - 0.19 11.7 12.0 0.37 10.8 12.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Phospholip_A2_1 PF00068.19 CBY32634.1 - 5e-17 62.4 6.6 5e-17 62.4 6.6 2.7 3 0 0 3 3 3 1 Phospholipase A2 GlcNAc_2-epim PF07221.11 CBY32635.1 - 2.3e-09 37.0 0.3 3.2e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) GlcNAc_2-epim PF07221.11 CBY32636.1 - 2.4e-06 27.0 0.0 2.6e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pkinase PF00069.25 CBY32637.1 - 5.2e-60 203.0 0.0 1.1e-59 202.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY32637.1 - 3.7e-34 116.7 0.3 4.9e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY32637.1 - 1.6e-27 96.5 0.0 3.3e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY32637.1 - 0.00018 21.0 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY32637.1 - 0.0025 17.8 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Golgin_A5 PF09787.9 CBY32637.1 - 0.12 11.9 5.5 0.24 10.8 5.5 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Sugar_tr PF00083.24 CBY32638.1 - 7.4e-13 48.2 0.2 9.3e-13 47.8 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY32638.1 - 1.3e-10 40.8 8.6 1.7e-10 40.4 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.21 CBY32638.1 - 4.2 7.4 5.3 0.63 10.0 1.1 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Lectin_C PF00059.21 CBY32640.1 - 6.7e-08 33.2 0.7 2.4e-07 31.4 0.4 2.0 2 0 0 2 2 2 1 Lectin C-type domain Cys_Knot_tox PF17486.2 CBY32640.1 - 0.049 13.9 0.3 0.11 12.7 0.3 1.6 1 0 0 1 1 1 0 Cystine knot toxins EGF PF00008.27 CBY32641.1 - 0.42 11.0 17.3 1.7 9.0 0.4 3.6 2 2 1 3 3 3 0 EGF-like domain hEGF PF12661.7 CBY32641.1 - 0.61 10.8 0.2 0.61 10.8 0.2 4.1 3 1 0 3 3 3 0 Human growth factor-like EGF MAM PF00629.23 CBY32643.1 - 0.08 12.9 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 MAM domain, meprin/A5/mu Astacin PF01400.24 CBY32644.1 - 9.4e-35 120.0 0.3 2.9e-30 105.3 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 CBY32644.1 - 0.062 13.1 0.5 0.16 11.8 0.3 1.7 1 1 0 1 1 1 0 Matrixin ASF1_hist_chap PF04729.13 CBY32646.1 - 2.4e-67 225.7 0.2 3.1e-67 225.3 0.2 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone HORMA PF02301.18 CBY32647.1 - 5.6e-05 22.8 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 HORMA domain NDUF_B8 PF05821.11 CBY32648.1 - 2.2e-17 63.5 1.7 3.1e-17 63.0 1.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) HK_sensor PF16750.5 CBY32648.1 - 0.47 10.8 1.3 0.95 9.8 1.3 1.4 1 0 0 1 1 1 0 Sensor domain of 2-component histidine kinase Aldedh PF00171.22 CBY32649.1 - 4.6e-122 407.8 0.1 2e-120 402.5 0.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family PseudoU_synth_2 PF00849.22 CBY32649.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase Sds3 PF08598.11 CBY32650.1 - 1.1e-05 25.6 12.3 1.3e-05 25.3 11.4 1.5 1 1 1 2 2 2 1 Sds3-like SSXRD PF09514.10 CBY32650.1 - 0.27 10.8 2.2 0.78 9.4 2.2 1.8 1 0 0 1 1 1 0 SSXRD motif Exonuc_VII_L PF02601.15 CBY32650.1 - 0.69 9.4 8.0 0.89 9.1 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAD_binding_6 PF00970.24 CBY32651.1 - 1.6e-27 95.7 0.0 2.7e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBY32651.1 - 5.5e-25 88.1 0.0 8.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY32651.1 - 8.3e-05 22.8 0.0 0.00016 21.8 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain START PF01852.19 CBY32652.1 - 9e-21 74.2 0.9 3.7e-20 72.2 0.8 2.1 2 1 0 2 2 2 1 START domain PH PF00169.29 CBY32652.1 - 2.1e-12 47.5 0.2 7.3e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 PH domain DUF5082 PF16888.5 CBY32652.1 - 0.0022 18.2 3.2 0.0022 18.2 3.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) PH_8 PF15409.6 CBY32652.1 - 0.0043 17.3 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CBY32652.1 - 0.018 15.4 4.7 0.19 12.2 0.3 3.0 2 1 0 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 CBY32652.1 - 0.037 14.4 0.0 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain VPS53_C PF16854.5 CBY32652.1 - 0.038 13.9 0.2 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus DivIC PF04977.15 CBY32652.1 - 0.051 13.4 3.7 0.32 10.8 0.0 3.0 3 0 0 3 3 3 0 Septum formation initiator AKNA PF12443.8 CBY32652.1 - 0.056 14.1 4.4 0.41 11.3 0.2 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor Dimerisation2 PF16864.5 CBY32653.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain Nucleoporin_FG2 PF15967.5 CBY32654.1 - 6.1e-30 104.3 35.8 8.8e-29 100.5 35.8 2.0 1 1 0 1 1 1 1 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 CBY32654.1 - 4.6e-10 40.2 71.2 4.6e-07 30.6 30.9 2.9 1 1 1 2 2 2 2 Nucleoporin FG repeat region Spc7 PF08317.11 CBY32654.1 - 0.56 9.0 7.5 0.11 11.3 4.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein MTBP_N PF14918.6 CBY32655.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 MDM2-binding T2SSM PF04612.12 CBY32655.1 - 0.14 12.2 0.1 0.36 10.9 0.2 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Homeodomain PF00046.29 CBY32656.1 - 1.1e-18 66.9 0.3 1.8e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Collagen PF01391.18 CBY32657.1 - 1.6e-63 210.4 203.4 2.7e-09 36.6 20.7 8.4 1 1 6 7 7 7 7 Collagen triple helix repeat (20 copies) COLFI PF01410.18 CBY32657.1 - 5.6e-08 32.4 0.1 1.5e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Fibrillar collagen C-terminal domain SAM_decarbox PF01536.16 CBY32658.1 - 4.7e-108 361.4 0.4 5.3e-108 361.2 0.4 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase A_deaminase PF00962.22 CBY32659.1 - 2.5e-66 224.3 0.0 2.3e-65 221.1 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase EF-hand_1 PF00036.32 CBY32660.1 - 1e-09 37.2 3.1 2.9e-05 23.3 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY32660.1 - 2.1e-09 37.7 1.8 2.9e-09 37.3 1.8 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY32660.1 - 1.8e-08 33.7 1.6 8.6e-05 22.2 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY32660.1 - 0.0015 17.9 1.2 0.2 11.2 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY32660.1 - 0.005 16.6 2.7 0.019 14.8 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair Kelch_6 PF13964.6 CBY32661.1 - 0.0015 18.8 0.2 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY32661.1 - 0.0037 17.2 0.4 3.1 7.9 0.0 2.7 2 0 0 2 2 2 2 Kelch motif T3SS_NleG PF06416.12 CBY32661.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Effector protein NleG Kelch_6 PF13964.6 CBY32662.1 - 0.0057 16.9 1.2 3 8.3 0.0 2.9 2 1 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY32662.1 - 0.027 14.5 0.2 5.1 7.2 0.0 2.8 2 0 0 2 2 2 0 Kelch motif PI-PLC-X PF00388.19 CBY32665.1 - 1.8e-47 160.5 0.1 2.6e-46 156.8 0.0 2.5 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY32665.1 - 1.6e-32 112.3 0.0 3e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBY32665.1 - 1.3e-15 57.5 0.1 3.9e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 C2 domain Kelch_4 PF13418.6 CBY32668.1 - 0.0026 17.7 2.6 9.5 6.3 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY32668.1 - 0.067 13.5 0.5 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY32668.1 - 0.11 12.6 1.9 1.6 8.8 0.0 3.0 4 0 0 4 4 4 0 Kelch motif HECT PF00632.25 CBY32671.1 - 1.5e-80 270.9 0.1 2.7e-80 270.1 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SAM_4 PF18017.1 CBY32671.1 - 0.029 14.3 0.1 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) IRK_C PF17655.1 CBY32672.1 - 8.8e-67 224.1 0.3 1.2e-66 223.7 0.3 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY32672.1 - 3.9e-42 143.4 2.5 7.9e-42 142.4 2.5 1.5 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY32672.1 - 0.00029 20.8 5.3 0.0006 19.7 5.3 1.6 1 0 0 1 1 1 1 Ion channel DUF4542 PF15075.6 CBY32673.1 - 0.067 13.6 0.1 0.093 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) OTOS PF15182.6 CBY32673.1 - 0.079 12.9 0.3 0.23 11.4 0.2 1.8 2 0 0 2 2 2 0 Otospiralin TSP_1 PF00090.19 CBY32674.1 - 5.2e-05 23.4 7.2 0.00026 21.1 7.2 2.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain PAN_4 PF14295.6 CBY32674.1 - 0.0013 18.6 0.4 0.0013 18.6 0.4 3.7 4 1 0 4 4 4 1 PAN domain PAN_3 PF08277.12 CBY32674.1 - 0.03 14.1 0.7 0.03 14.1 0.7 3.1 2 1 1 3 3 3 0 PAN-like domain Peptidase_M16 PF00675.20 CBY32675.1 - 1.2e-21 77.3 0.1 2e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY32675.1 - 9.5e-08 32.3 0.1 2.2e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CBY32676.1 - 1.2e-23 83.8 0.0 7.4e-21 74.7 0.0 3.2 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBY32676.1 - 0.00039 20.5 0.0 0.022 14.7 0.0 2.3 2 1 0 2 2 2 2 Peptidase M16 inactive domain DnaJ PF00226.31 CBY32677.1 - 6.2e-09 35.9 0.1 1.3e-06 28.4 0.1 2.4 1 1 0 1 1 1 1 DnaJ domain Homeodomain PF00046.29 CBY32678.1 - 6e-11 42.0 2.2 1.3e-10 40.9 2.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY32678.1 - 7.2e-05 22.6 0.6 0.00022 21.0 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain CotJA PF11007.8 CBY32678.1 - 0.047 13.5 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) zf-C2H2 PF00096.26 CBY32679.1 - 1.1e-16 60.3 29.2 1.2e-07 31.8 0.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY32679.1 - 5.5e-15 55.0 9.1 2.8e-09 37.0 2.5 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY32679.1 - 1.5e-09 37.8 29.2 0.00018 22.1 0.5 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY32679.1 - 2.7e-05 24.4 3.4 2.7e-05 24.4 3.4 1.6 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CBY32679.1 - 3.9e-05 23.8 2.9 0.97 9.8 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY32679.1 - 5.5e-05 23.1 12.8 0.022 14.8 0.2 3.3 3 1 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.15 CBY32679.1 - 0.00078 19.4 7.6 2.3 8.3 0.2 3.6 2 1 1 3 3 3 2 BED zinc finger FOXP-CC PF16159.5 CBY32679.1 - 0.0015 19.1 15.1 0.0041 17.7 0.2 3.6 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-Di19 PF05605.12 CBY32679.1 - 0.0053 17.0 2.2 0.0053 17.0 2.2 3.8 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 CBY32679.1 - 0.0068 16.3 17.1 0.08 12.9 0.2 3.3 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-met PF12874.7 CBY32679.1 - 0.021 15.2 5.4 1.9 9.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 CBY32679.1 - 0.027 15.2 2.0 0.027 15.2 2.0 2.7 2 1 1 3 3 3 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 CBY32679.1 - 0.04 13.7 0.0 0.04 13.7 0.0 4.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBY32679.1 - 0.27 11.4 2.1 11 6.1 0.1 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger PyrI_C PF02748.15 CBY32679.1 - 0.37 10.7 0.2 0.37 10.7 0.2 3.3 3 1 1 4 4 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain IBR PF01485.21 CBY32679.1 - 5.4 7.3 15.5 0.4 10.9 4.2 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_2 PF12756.7 CBY32679.1 - 8 6.9 12.3 3 8.2 1.7 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SIX1_SD PF16878.5 CBY32680.1 - 1.3e-46 157.7 0.1 2.7e-46 156.7 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY32680.1 - 9.8e-15 54.2 0.8 1.2e-13 50.6 0.3 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY32680.1 - 2.5e-13 49.7 1.0 1e-12 47.7 0.4 2.3 2 0 0 2 2 2 1 Homeobox KN domain HTH_3 PF01381.22 CBY32680.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Homez PF11569.8 CBY32680.1 - 0.025 14.1 0.2 0.069 12.6 0.1 1.8 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 CBY32680.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Crp_2 PF13545.6 CBY32680.1 - 0.13 12.3 0.0 23 5.0 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Spt20 PF12090.8 CBY32680.1 - 3.1 7.4 12.5 0.022 14.4 2.4 2.1 2 0 0 2 2 2 0 Spt20 family zf-C2H2 PF00096.26 CBY32681.1 - 1.8e-08 34.4 5.0 0.0023 18.3 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY32681.1 - 1.6e-05 25.1 0.9 0.031 14.6 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Nepo_coat PF03391.15 CBY32681.1 - 0.0016 18.0 0.2 0.006 16.1 0.0 1.8 2 0 0 2 2 2 1 Nepovirus coat protein, central domain zf-met PF12874.7 CBY32681.1 - 0.0078 16.6 0.3 0.0078 16.6 0.3 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY32681.1 - 0.013 16.3 15.9 0.033 15.0 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY32681.1 - 0.035 14.5 0.3 0.035 14.5 0.3 2.2 2 1 1 3 3 3 0 Zinc-finger double domain Transpos_assoc PF13963.6 CBY32681.1 - 4.6 7.6 7.8 1.7 9.0 3.9 2.1 1 1 2 3 3 3 0 Transposase-associated domain Acetyltransf_1 PF00583.25 CBY32682.1 - 2.2e-13 50.5 0.1 3.3e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY32682.1 - 3.5e-08 33.8 0.1 6.6e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY32682.1 - 8.5e-07 29.0 0.1 2e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY32682.1 - 1.2e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY32682.1 - 0.003 17.6 0.2 0.012 15.7 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY32682.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein PanZ PF12568.8 CBY32682.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Myb_DNA-bind_6 PF13921.6 CBY32682.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C2H2 PF00096.26 CBY32683.1 - 0.026 15.0 1.2 0.026 15.0 1.2 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type GATA PF00320.27 CBY32683.1 - 0.17 11.5 18.1 0.74 9.5 0.8 4.8 5 0 0 5 5 5 0 GATA zinc finger zf-C2H2_jaz PF12171.8 CBY32683.1 - 1.2 9.5 5.9 0.26 11.6 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HNH PF01844.23 CBY32683.1 - 5.9 7.1 10.1 0.18 12.0 1.9 2.7 2 0 0 2 2 2 0 HNH endonuclease RRM_1 PF00076.22 CBY32684.1 - 3.3e-33 113.3 0.7 4e-17 61.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY32684.1 - 6.7e-09 35.7 0.5 0.0046 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY32684.1 - 0.012 15.7 0.2 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.11 CBY32684.1 - 0.019 14.6 0.8 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 CBY32684.1 - 0.039 14.2 0.1 1.2 9.3 0.0 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter EAP30 PF04157.16 CBY32685.1 - 5e-29 101.3 0.9 6.6e-29 100.9 0.9 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CBY32685.1 - 1e-06 28.8 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Striatin PF08232.12 CBY32686.1 - 1e-38 133.3 1.3 1e-38 133.3 1.3 3.4 3 1 0 3 3 3 1 Striatin family WD40 PF00400.32 CBY32686.1 - 8.6e-29 99.2 8.2 3.2e-06 27.8 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY32686.1 - 1e-06 29.0 3.3 3.6 8.0 0.1 5.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY32686.1 - 3.6e-05 22.6 1.1 1.4 7.5 0.1 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 DUF4482 PF14818.6 CBY32686.1 - 0.099 13.5 0.5 0.099 13.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Nucleoporin_N PF08801.11 CBY32686.1 - 0.13 11.0 0.2 6 5.5 0.0 2.9 3 1 0 3 3 3 0 Nup133 N terminal like DUF4611 PF15387.6 CBY32686.1 - 1.1 9.5 5.6 14 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Brix PF04427.18 CBY32687.1 - 4.3e-33 115.0 0.1 6.1e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.29 CBY32688.1 - 1e-46 156.6 19.4 2.3e-12 46.5 0.3 4.6 5 0 0 5 5 5 4 KH domain RRM_1 PF00076.22 CBY32688.1 - 8.4e-18 64.0 0.0 8e-08 32.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_2 PF07650.17 CBY32688.1 - 2.4e-12 46.5 7.4 0.048 13.5 0.0 4.7 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY32688.1 - 1.6e-10 40.7 5.4 0.0038 17.1 0.1 4.7 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 CBY32688.1 - 4.8e-07 29.8 6.9 0.98 9.6 0.0 4.6 4 0 0 4 4 4 3 NusA-like KH domain DbpA PF03880.15 CBY32688.1 - 8.7e-06 25.6 1.5 0.19 11.7 0.0 4.1 4 0 0 4 4 4 2 DbpA RNA binding domain MOEP19 PF16005.5 CBY32688.1 - 0.00026 20.9 0.0 0.56 10.3 0.0 3.8 3 1 1 4 4 4 1 KH-like RNA-binding domain RRM_5 PF13893.6 CBY32688.1 - 0.00041 19.9 0.0 0.056 13.0 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY32688.1 - 0.003 17.4 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 CBY32689.1 - 9.1e-19 66.9 32.2 2.6e-06 27.2 1.0 5.5 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY32689.1 - 2.2e-18 65.7 44.8 6.8e-07 29.1 2.0 6.3 6 0 0 6 6 6 4 Zinc finger domain Torus PF16131.5 CBY32689.1 - 3.2e-14 53.5 27.7 0.00031 21.4 0.5 5.1 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 CBY32689.1 - 2.7e-12 46.2 24.8 1.4e-05 24.8 0.4 5.2 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBY32689.1 - 3.9e-09 36.7 26.1 7.6e-06 26.1 9.5 3.0 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBY32689.1 - 0.0042 17.5 34.9 0.17 12.4 2.1 6.1 5 1 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 CBY32689.1 - 0.02 14.9 4.3 0.02 14.9 4.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 CBY32689.1 - 0.58 9.9 14.9 0.99 9.2 0.2 4.4 4 0 0 4 4 4 0 Putative zinc-finger domain Pro_isomerase PF00160.21 CBY32692.1 - 2.2e-25 89.8 0.1 2.3e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CBY32693.1 - 1.6e-13 50.3 0.0 3.4e-07 30.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 CBY32693.1 - 0.012 15.9 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_occluded PF16842.5 CBY32693.1 - 0.097 12.5 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif AsnA PF03590.15 CBY32694.1 - 0.003 17.4 1.4 0.057 13.1 0.4 2.4 2 0 0 2 2 2 2 Aspartate-ammonia ligase O-FucT PF10250.9 CBY32695.1 - 0.0073 16.0 0.1 0.033 13.9 0.1 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Med8 PF10232.9 CBY32696.1 - 3.4e-39 134.8 0.1 4.3e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4410 PF14366.6 CBY32696.1 - 0.23 11.4 0.7 0.82 9.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) ThrE PF06738.12 CBY32696.1 - 0.26 10.6 0.1 0.6 9.4 0.1 1.6 2 0 0 2 2 2 0 Putative threonine/serine exporter RRM_1 PF00076.22 CBY32697.1 - 2.7e-14 52.8 0.0 4.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1329 PF07044.11 CBY32698.1 - 0.08 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) GGACT PF06094.12 CBY32699.1 - 1.2e-11 45.3 0.0 1.3e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CBY32699.1 - 0.00051 20.4 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family IIGP PF05049.13 CBY32700.1 - 1.8e-41 142.5 1.3 2.7e-41 141.9 1.3 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CBY32700.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF659 PF04937.15 CBY32700.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DPBB_1 PF03330.18 CBY32701.1 - 0.044 14.1 0.5 0.37 11.1 0.5 2.4 2 0 0 2 2 2 0 Lytic transglycolase Acetyltransf_1 PF00583.25 CBY32702.1 - 8.2e-14 51.8 0.0 1.4e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY32702.1 - 1.3e-10 41.3 0.4 3.8e-10 39.8 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY32702.1 - 2.6e-10 40.6 0.1 4.9e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY32702.1 - 1.7e-08 34.3 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 CBY32702.1 - 0.00029 20.6 0.1 0.00082 19.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 CBY32702.1 - 0.0084 15.6 0.2 0.018 14.5 0.2 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Cadherin_pro PF08758.11 CBY32702.1 - 0.076 13.2 0.1 0.18 12.0 0.1 1.8 1 1 0 1 1 1 0 Cadherin prodomain like Acetyltransf_CG PF14542.6 CBY32702.1 - 0.08 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase IRK_C PF17655.1 CBY32703.1 - 7.7e-53 178.7 0.1 1.1e-52 178.2 0.1 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY32703.1 - 1.8e-42 144.5 3.2 2.5e-42 144.0 3.2 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY32703.1 - 0.036 14.0 11.9 0.25 11.3 11.9 2.2 1 1 0 1 1 1 0 Ion channel Zona_pellucida PF00100.23 CBY32704.1 - 2.2e-17 63.7 4.1 3.8e-17 63.0 4.1 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Laminin_G_3 PF13385.6 CBY32704.1 - 2e-06 28.0 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily CwfJ_C_1 PF04677.15 CBY32706.1 - 7.2e-32 109.8 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CBY32706.1 - 4.1e-08 34.0 0.0 8.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Striatin PF08232.12 CBY32707.1 - 0.044 14.4 3.5 0.053 14.1 3.5 1.1 1 0 0 1 1 1 0 Striatin family IL31 PF15209.6 CBY32707.1 - 0.055 13.3 0.4 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Interleukin 31 E2F_CC-MB PF16421.5 CBY32707.1 - 0.14 12.6 4.4 0.18 12.2 3.8 1.7 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain SKA1 PF07160.12 CBY32707.1 - 0.27 11.1 5.7 0.3 10.9 5.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0193 PF05250.11 CBY32708.1 - 2.5e-35 122.3 13.0 2.8e-35 122.1 13.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) VPS28 PF03997.12 CBY32709.1 - 2.1e-50 171.0 2.7 2.1e-50 171.0 2.7 5.0 4 1 0 4 4 4 1 VPS28 protein GRIP PF01465.20 CBY32709.1 - 3.2e-09 36.6 0.0 7.7e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 GRIP domain LRR_6 PF13516.6 CBY32710.1 - 1e-08 34.5 8.6 2.5 8.4 0.0 6.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_8 PF13855.6 CBY32710.1 - 0.00035 20.3 4.8 0.064 13.0 0.2 3.7 2 2 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY32710.1 - 0.0026 18.1 10.0 2.8 8.5 0.6 4.9 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY32710.1 - 0.0061 16.9 4.6 1.3 9.8 0.0 4.9 6 0 0 6 6 6 1 Leucine Rich Repeat SNF PF00209.18 CBY32711.1 - 1.5e-163 545.3 32.3 1.7e-163 545.1 32.3 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Ldl_recept_a PF00057.18 CBY32712.1 - 4.6e-10 39.5 15.9 3.2e-09 36.9 9.2 2.2 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A DUF3439 PF11921.8 CBY32712.1 - 0.019 15.0 6.7 0.019 15.0 6.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY32712.1 - 0.8 7.6 7.8 1 7.2 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_LBD PF02931.23 CBY32713.1 - 1.1e-39 136.1 0.1 2e-39 135.3 0.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY32713.1 - 1.4e-08 35.1 0.0 5.7e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Resistin PF06954.11 CBY32717.1 - 0.047 14.2 2.0 0.047 14.2 2.0 3.4 4 0 0 4 4 4 0 Resistin Dicty_REP PF05086.12 CBY32717.1 - 0.37 8.7 3.2 0.48 8.3 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CBY32717.1 - 1.2 7.2 5.3 1.6 6.8 5.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 CBY32717.1 - 2.2 8.2 24.9 3.7 7.5 24.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 CBY32717.1 - 7 6.6 9.4 11 6.0 9.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RRM_1 PF00076.22 CBY32718.1 - 1.3e-18 66.5 1.1 2.9e-18 65.5 0.4 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY32718.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SKN1 PF03935.15 CBY32719.1 - 0.0062 15.0 0.1 0.0097 14.4 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Shisa PF13908.6 CBY32719.1 - 0.26 11.5 6.1 0.5 10.6 6.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator UBA_4 PF14555.6 CBY32720.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 CBY32720.1 - 0.00068 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 CBY32720.1 - 0.0055 16.6 0.6 0.033 14.1 0.6 2.4 1 1 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 CBY32720.1 - 0.017 15.2 0.6 0.02 14.9 0.6 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair YopE_N PF09020.10 CBY32720.1 - 0.065 13.5 0.5 0.096 12.9 0.4 1.4 1 1 0 1 1 1 0 YopE, N terminal DUF2203 PF09969.9 CBY32720.1 - 0.093 13.5 0.1 0.11 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2250 PF10007.9 CBY32720.1 - 0.099 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DHHC PF01529.20 CBY32723.1 - 9.1e-24 84.1 5.2 9.1e-24 84.1 5.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase SH3_9 PF14604.6 CBY32723.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY32723.1 - 0.0016 18.1 0.0 0.0048 16.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY32723.1 - 0.044 13.4 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain PRiA4_ORF3 PF07929.11 CBY32723.1 - 0.086 12.5 0.1 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein ERAP1_C PF11838.8 CBY32724.1 - 1e-07 31.8 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain ERAP1_C PF11838.8 CBY32725.1 - 1e-24 87.7 0.1 1.2e-24 87.5 0.1 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CBY32726.1 - 8.1e-87 290.4 0.1 1.1e-86 289.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY32726.1 - 4.6e-49 167.1 0.3 6.4e-49 166.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF1378 PF07125.11 CBY32728.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Ctr PF04145.15 CBY32730.1 - 3e-17 63.6 13.1 8.6e-09 36.2 7.3 2.4 1 1 1 2 2 2 2 Ctr copper transporter family Voltage_CLC PF00654.20 CBY32730.1 - 0.0032 16.8 2.3 0.0039 16.5 2.3 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel Sugar_tr PF00083.24 CBY32731.1 - 7e-32 110.9 19.6 1.2e-31 110.1 19.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY32731.1 - 2.7e-24 85.8 19.4 2.7e-24 85.8 19.4 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF3439 PF11921.8 CBY32732.1 - 0.007 16.3 1.3 0.007 16.3 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) PAX PF00292.18 CBY32733.1 - 9.5e-60 200.0 0.5 1.8e-59 199.1 0.5 1.5 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY32733.1 - 1.2e-23 82.7 1.4 1.9e-23 82.0 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY32733.1 - 2.6e-05 24.0 0.1 9e-05 22.3 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 CBY32733.1 - 0.00019 21.1 1.0 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 CBY32733.1 - 0.018 15.1 0.5 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 CBY32733.1 - 0.068 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_31 PF13560.6 CBY32733.1 - 0.073 13.4 0.7 2.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MRP-L20 PF12824.7 CBY32733.1 - 0.13 12.4 0.2 0.13 12.4 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 Sec62 PF03839.16 CBY32734.1 - 7.9 5.9 7.5 1 8.8 1.7 1.9 1 1 1 2 2 2 0 Translocation protein Sec62 DUF4473 PF14747.6 CBY32735.1 - 0.015 15.8 1.7 0.066 13.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) NPCC PF08058.11 CBY32736.1 - 1.7 8.7 3.4 1.7 8.7 1.3 2.0 2 0 0 2 2 2 0 Nuclear pore complex component Laminin_N PF00055.17 CBY32737.1 - 6e-61 206.0 0.1 6e-61 206.0 0.1 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY32737.1 - 3.9e-18 65.3 64.6 6.3e-06 26.2 18.1 4.3 3 1 0 3 3 3 3 Laminin EGF domain F5_F8_type_C PF00754.25 CBY32737.1 - 1.5e-05 25.1 0.4 7.8e-05 22.8 0.2 2.4 3 0 0 3 3 3 1 F5/8 type C domain Laminin_G_2 PF02210.24 CBY32737.1 - 0.0074 16.9 0.1 0.024 15.2 0.1 2.0 1 0 0 1 1 1 1 Laminin G domain TIG_2 PF18020.1 CBY32737.1 - 0.16 12.6 1.1 0.45 11.2 1.1 1.8 1 0 0 1 1 1 0 TIG domain found in plexin DASH_Duo1 PF08651.10 CBY32737.1 - 0.56 10.0 2.7 37 4.2 0.3 4.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 MARVEL PF01284.23 CBY32738.1 - 0.0044 17.1 7.0 0.0059 16.6 7.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain CTV_P6 PF06706.11 CBY32738.1 - 0.037 13.7 0.6 0.1 12.3 0.6 1.9 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DUF3976 PF13121.6 CBY32738.1 - 0.78 9.9 3.1 0.72 10.0 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) Septin PF00735.18 CBY32740.1 - 1.4e-127 424.8 0.1 1.8e-127 424.4 0.1 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CBY32740.1 - 3.3e-08 33.6 0.0 9.1e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY32740.1 - 3.3e-07 30.3 0.3 4e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBY32740.1 - 2.9e-06 26.9 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CBY32740.1 - 5e-05 22.7 0.0 0.00013 21.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CBY32740.1 - 0.00038 20.6 1.0 0.17 12.0 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 CBY32740.1 - 0.0022 18.2 0.2 0.013 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 CBY32740.1 - 0.0024 17.5 0.1 0.0097 15.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CBY32740.1 - 0.0033 17.6 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY32740.1 - 0.0051 17.3 0.1 0.03 14.8 0.0 2.2 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CBY32740.1 - 0.0066 16.8 0.0 0.016 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBY32740.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBY32740.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CBY32740.1 - 0.1 13.1 1.1 0.41 11.1 1.1 2.0 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CBY32740.1 - 0.13 11.6 0.4 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CS PF04969.16 CBY32741.1 - 1e-07 32.9 2.6 1.1e-07 32.7 0.5 2.3 2 0 0 2 2 2 1 CS domain TPR_11 PF13414.6 CBY32741.1 - 1.2e-05 24.9 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 CBY32741.1 - 1.8e-05 24.5 1.9 0.075 13.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY32741.1 - 4.8e-05 23.9 0.2 0.0034 18.0 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY32741.1 - 0.00016 21.3 0.1 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY32741.1 - 0.0005 20.7 0.1 0.99 10.4 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY32741.1 - 0.018 15.2 0.1 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PAS_6 PF08348.11 CBY32741.1 - 0.53 10.2 2.6 3.9 7.4 0.0 3.0 2 1 1 3 3 3 0 YheO-like PAS domain SOBP PF15279.6 CBY32741.1 - 0.65 10.6 6.2 0.9 10.1 6.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein adh_short PF00106.25 CBY32743.1 - 2.1e-22 79.6 0.0 3.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY32743.1 - 2.8e-13 50.0 0.0 4.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1053 PF06327.14 CBY32744.1 - 0.063 13.8 1.0 0.2 12.2 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Galactosyl_T PF01762.21 CBY32745.1 - 4.3e-21 75.6 0.0 1e-20 74.4 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase CagS PF16707.5 CBY32745.1 - 0.079 13.0 3.4 0.61 10.1 0.2 2.3 2 0 0 2 2 2 0 Cag pathogenicity island protein S of Helicobacter pylori RepL PF05732.11 CBY32745.1 - 0.083 12.3 2.5 0.2 11.1 0.7 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) COesterase PF00135.28 CBY32747.1 - 2.6e-79 267.5 0.0 3.4e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY32747.1 - 3.7e-05 23.7 1.2 0.00032 20.6 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY32747.1 - 0.001 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Trypsin PF00089.26 CBY32748.1 - 3.6e-30 105.4 0.1 8e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Trypsin EGF PF00008.27 CBY32748.1 - 2.9e-08 33.8 45.6 7.9e-07 29.3 7.8 4.4 4 0 0 4 4 4 3 EGF-like domain EGF_CA PF07645.15 CBY32748.1 - 3.2e-06 27.2 10.2 3.2e-06 27.2 10.2 4.7 3 1 1 4 4 4 1 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY32748.1 - 3.8e-06 26.8 4.3 3.8e-06 26.8 4.3 3.9 3 0 0 3 3 3 1 MSP1 EGF domain 1 EGF_3 PF12947.7 CBY32748.1 - 0.00035 20.7 7.1 0.00035 20.7 7.1 4.2 3 0 0 3 3 3 1 EGF domain hEGF PF12661.7 CBY32748.1 - 0.00042 20.8 6.2 0.00042 20.8 6.2 4.6 3 0 0 3 3 3 1 Human growth factor-like EGF DUF1986 PF09342.11 CBY32748.1 - 0.0055 17.1 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) EGF_2 PF07974.13 CBY32748.1 - 0.038 14.4 10.3 0.038 14.4 10.3 4.8 4 0 0 4 4 4 0 EGF-like domain FXa_inhibition PF14670.6 CBY32748.1 - 0.3 11.4 27.1 0.33 11.3 7.2 4.4 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site CAP PF00188.26 CBY32749.1 - 4.2e-38 131.0 3.2 7.3e-20 72.1 0.4 2.5 2 1 1 3 3 3 2 Cysteine-rich secretory protein family Sugar_tr PF00083.24 CBY32750.1 - 1.9e-12 46.8 1.4 2.7e-12 46.3 1.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY32750.1 - 3.7e-09 36.0 4.5 1.2e-08 34.4 4.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY32751.1 - 0.00015 20.8 0.2 0.00018 20.5 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY32752.1 - 4.2e-09 35.8 5.8 4.8e-09 35.6 5.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY32752.1 - 1e-06 27.9 7.2 1.2e-06 27.7 7.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Gate PF07670.14 CBY32752.1 - 0.04 14.2 0.1 0.13 12.6 0.1 2.0 1 1 0 1 1 1 0 Nucleoside recognition Transport_MerF PF11431.8 CBY32752.1 - 4.8 7.1 6.5 1.1 9.2 0.7 2.7 2 1 1 3 3 3 0 Membrane transport protein MerF SBF PF01758.16 CBY32755.1 - 1.5e-25 90.1 15.1 1.5e-25 90.1 15.1 1.8 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF1218 PF06749.12 CBY32756.1 - 0.45 11.1 5.8 21 5.7 5.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) DUF5408 PF17402.2 CBY32756.1 - 0.55 10.2 4.7 0.12 12.2 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5408) Comm PF15957.5 CBY32756.1 - 0.87 10.0 4.0 5 7.5 4.0 2.1 1 1 0 1 1 1 0 Commissureless MLANA PF14991.6 CBY32757.1 - 0.0069 16.7 0.1 0.0081 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein melan-A WBP-1 PF11669.8 CBY32757.1 - 0.45 11.2 2.2 0.59 10.8 2.2 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 Zona_pellucida PF00100.23 CBY32758.1 - 4.2e-39 134.9 6.3 5.3e-39 134.6 6.3 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain CPSase_sm_chain PF00988.22 CBY32758.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Kringle PF00051.18 CBY32759.1 - 1.5e-24 86.1 4.8 2.5e-24 85.4 4.8 1.3 1 0 0 1 1 1 1 Kringle domain DUF5512 PF17631.2 CBY32760.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5512) DUF2053 PF09767.9 CBY32761.1 - 7.5e-49 165.9 4.9 1.2e-48 165.3 4.9 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) WD40 PF00400.32 CBY32762.1 - 4.5e-13 49.4 10.7 2e-05 25.3 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat mRNA_cap_enzyme PF01331.19 CBY32763.1 - 1.8e-62 210.7 0.1 1e-61 208.2 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CBY32763.1 - 1.1e-20 74.2 0.0 2.2e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 CBY32763.1 - 4.4e-10 39.5 0.0 1.1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 CBY32763.1 - 0.0072 16.0 0.0 0.26 10.9 0.0 2.5 1 1 1 2 2 2 1 ATP dependent DNA ligase domain FAD-oxidase_C PF02913.19 CBY32764.1 - 5.2e-45 154.0 0.0 6.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBY32764.1 - 5.1e-20 71.6 0.1 1.7e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain AMP-binding PF00501.28 CBY32765.1 - 1.4e-12 46.9 0.0 2.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme RT_RNaseH_2 PF17919.1 CBY32766.1 - 1.2e-23 83.0 0.5 4.1e-23 81.3 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY32766.1 - 1.3e-13 51.1 0.4 3.2e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY32766.1 - 5e-13 49.3 0.1 1.6e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY32766.1 - 2.2e-11 43.7 0.0 2.5e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY32766.1 - 2.7e-11 43.4 0.1 8.4e-11 41.8 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 CBY32766.1 - 5.3e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY32766.1 - 3.5e-05 24.3 0.0 0.00011 22.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PIN_8 PF18476.1 CBY32766.1 - 0.031 14.1 0.1 0.13 12.1 0.1 2.0 1 0 0 1 1 1 0 PIN like domain RVT_thumb PF06817.14 CBY32766.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF1758 PF05585.12 CBY32766.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) AMP-binding PF00501.28 CBY32767.1 - 3.4e-28 98.4 0.0 4.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TSP_1 PF00090.19 CBY32768.1 - 1.4e-86 284.5 240.8 3.1e-09 36.9 7.7 13.5 14 0 0 14 14 14 13 Thrombospondin type 1 domain HXXSHH PF07586.11 CBY32769.1 - 0.093 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Herpes_UL95 PF03038.14 CBY32770.1 - 0.075 12.2 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 UL95 family ALMT PF11744.8 CBY32770.1 - 0.2 10.4 5.5 0.26 10.1 5.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Herpes_capsid PF06112.11 CBY32772.1 - 0.28 11.2 11.0 0.36 10.9 11.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4701 PF15773.5 CBY32772.1 - 0.3 10.0 7.9 0.35 9.8 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) Mucin PF01456.17 CBY32772.1 - 0.37 10.8 22.1 0.44 10.5 22.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 CBY32772.1 - 0.38 8.8 7.5 0.42 8.7 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM199X PF15814.5 CBY32772.1 - 0.5 9.4 5.9 0.56 9.2 5.9 1.1 1 0 0 1 1 1 0 Protein family FAM199X DUF2057 PF09829.9 CBY32772.1 - 0.78 9.9 8.6 0.97 9.6 8.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FSA_C PF10479.9 CBY32772.1 - 1.2 7.1 15.4 1.4 6.9 15.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glycoprotein PF03409.15 CBY32772.1 - 2.4 6.9 10.9 2.6 6.8 10.9 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein PepSY_like PF11396.8 CBY32773.1 - 0.49 11.0 3.3 5 7.7 0.1 2.5 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Pkinase PF00069.25 CBY32774.1 - 6.8e-49 166.6 0.0 1.5e-48 165.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32774.1 - 9.4e-32 110.3 0.0 1.8e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY32774.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APG6_N PF17675.1 CBY32774.1 - 0.011 16.3 6.1 0.011 16.3 6.1 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF3050 PF11251.8 CBY32774.1 - 0.089 12.4 2.7 0.24 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) Sulfate_transp PF00916.20 CBY32775.1 - 9e-66 222.2 7.9 1.6e-39 135.8 0.7 3.0 2 1 0 2 2 2 2 Sulfate permease family STAS PF01740.21 CBY32775.1 - 3.3e-09 36.4 0.0 1.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 CBY32775.1 - 0.35 11.3 7.7 0.065 13.6 2.0 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily EF1G PF00647.19 CBY32776.1 - 0.033 14.2 2.4 0.17 11.9 0.4 2.4 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain RNA_replicase_B PF03431.13 CBY32776.1 - 0.046 12.2 0.7 0.085 11.3 0.4 1.5 1 1 0 1 1 1 0 RNA replicase, beta-chain Tox-REase-5 PF15648.6 CBY32776.1 - 0.067 13.7 1.9 0.83 10.2 0.3 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 HALZ PF02183.18 CBY32776.1 - 0.079 13.2 0.6 0.079 13.2 0.6 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.10 CBY32776.1 - 0.7 9.7 4.6 14 5.6 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 GAS PF13851.6 CBY32776.1 - 6.6 6.0 36.1 0.038 13.4 11.3 3.3 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Kin17_mid PF10357.9 CBY32777.1 - 1.4e-41 141.3 0.5 1.4e-41 141.3 0.5 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 CBY32777.1 - 2.3e-06 27.6 3.4 2.1e-05 24.5 0.6 2.6 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 CBY32777.1 - 0.027 14.9 5.2 0.027 14.9 5.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2533 PF10752.9 CBY32777.1 - 0.033 14.6 0.3 0.1 13.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) zf-C2H2_jaz PF12171.8 CBY32777.1 - 6.6 7.1 14.0 0.058 13.7 5.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PQQ_2 PF13360.6 CBY32778.1 - 0.0015 18.2 0.1 0.37 10.3 0.0 3.2 3 1 0 3 3 3 2 PQQ-like domain Pkinase PF00069.25 CBY32779.1 - 1.3e-09 37.8 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32779.1 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY32779.1 - 0.42 10.8 3.4 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) BTB PF00651.31 CBY32780.1 - 7.7e-07 29.3 0.4 1.7e-06 28.2 0.4 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY32780.1 - 1.5e-05 25.0 1.1 3.1e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_6 PF13964.6 CBY32782.1 - 1.3e-06 28.4 6.3 0.42 11.0 0.1 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBY32782.1 - 3e-05 23.5 4.3 0.42 10.2 1.1 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY32782.1 - 0.00021 21.2 5.2 1.3 9.1 0.1 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY32782.1 - 0.0073 16.2 1.3 5.9 7.0 0.2 4.0 4 0 0 4 4 4 1 Kelch motif zf-C4 PF00105.18 CBY32783.1 - 6.4e-15 55.4 10.5 1.3e-14 54.4 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 CBY32783.1 - 0.062 13.4 4.0 0.13 12.3 4.0 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type EF-hand_8 PF13833.6 CBY32784.1 - 4.2e-10 39.3 1.2 3.1e-09 36.5 0.5 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY32784.1 - 1.6e-08 34.9 2.7 6.7e-08 32.9 1.2 2.4 1 1 1 2 2 2 1 EF-hand domain pair S_100 PF01023.19 CBY32784.1 - 5.3e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain EF-hand_6 PF13405.6 CBY32784.1 - 8.4e-07 28.4 2.3 0.0044 16.9 0.7 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY32784.1 - 1.2e-06 27.6 0.6 3.5e-05 23.0 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBY32784.1 - 0.00011 21.6 2.3 0.0014 18.0 0.8 2.5 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 CBY32784.1 - 0.00047 20.6 0.4 0.072 13.6 0.2 2.1 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_4 PF12763.7 CBY32784.1 - 0.00099 19.0 0.4 0.0012 18.8 0.4 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY32784.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Phospholip_A2_1 PF00068.19 CBY32785.1 - 8.5e-17 61.6 9.2 8.5e-17 61.6 9.2 1.6 2 0 0 2 2 2 1 Phospholipase A2 AMP-binding PF00501.28 CBY32786.1 - 4.4e-42 144.1 0.3 6.4e-42 143.6 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY32786.1 - 0.17 12.9 0.0 0.48 11.5 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf-RING_5 PF14634.6 CBY32787.1 - 6.3e-08 32.5 17.3 6.3e-08 32.5 17.3 3.1 3 1 1 4 4 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY32787.1 - 4.8e-05 23.6 15.0 4.8e-05 23.6 15.0 3.0 2 1 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY32787.1 - 0.004 17.1 28.4 0.0056 16.7 9.0 4.1 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY32787.1 - 0.0061 16.4 13.6 0.0061 16.4 13.6 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY32787.1 - 0.008 16.0 12.2 0.008 16.0 12.2 2.9 2 2 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY32787.1 - 0.0082 15.9 14.6 0.0082 15.9 14.6 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 CBY32787.1 - 0.013 14.9 10.4 0.013 14.9 10.4 3.0 1 1 2 3 3 1 0 Rtf2 RING-finger Hamartin PF04388.12 CBY32787.1 - 0.046 12.4 12.2 0.06 12.0 12.2 1.1 1 0 0 1 1 1 0 Hamartin protein HrcA PF01628.21 CBY32787.1 - 0.16 11.9 6.4 4.7 7.0 0.1 2.1 2 0 0 2 2 2 0 HrcA protein C terminal domain STATa_Ig PF18214.1 CBY32787.1 - 0.19 11.8 3.8 0.28 11.2 3.1 1.7 1 1 0 1 1 1 0 STATa Immunoglobulin-like domain Presenilin PF01080.17 CBY32787.1 - 4.6 5.9 7.8 6 5.5 7.8 1.2 1 0 0 1 1 1 0 Presenilin EGF_3 PF12947.7 CBY32788.1 - 0.00021 21.4 9.4 0.00041 20.5 9.4 1.5 1 0 0 1 1 1 1 EGF domain DUF410 PF04190.13 CBY32788.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) EGF_MSP1_1 PF12946.7 CBY32788.1 - 0.13 12.3 5.9 0.25 11.4 5.9 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 Collagen PF01391.18 CBY32790.1 - 8.5e-07 28.6 16.7 2e-06 27.5 16.7 1.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) GCN5L1 PF06320.13 CBY32790.1 - 0.17 12.0 2.4 2.7 8.2 0.2 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) SHIPPO-rpt PF07004.12 CBY32791.1 - 6.8e-12 45.7 27.0 0.037 14.9 1.3 7.1 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat BBE PF08031.12 CBY32791.1 - 0.012 15.7 0.0 5.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Berberine and berberine like Dynein_AAA_lid PF17852.1 CBY32791.1 - 0.048 13.7 0.1 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain VWC PF00093.18 CBY32792.1 - 3e-16 59.5 83.4 7.8e-07 29.3 10.3 10.6 7 3 3 10 10 10 4 von Willebrand factor type C domain Antistasin PF02822.14 CBY32792.1 - 2.3e-15 56.9 37.3 5e-10 39.8 6.8 14.1 13 3 1 14 14 14 3 Antistasin family PSP94 PF05825.11 CBY32792.1 - 0.018 15.6 5.0 0.018 15.6 5.0 7.6 4 2 3 7 7 7 0 Beta-microseminoprotein (PSP-94) CFC PF09443.10 CBY32792.1 - 0.02 14.7 2.8 0.02 14.7 2.8 9.6 8 0 0 8 8 8 0 Cripto_Frl-1_Cryptic (CFC) DUF2633 PF11119.8 CBY32793.1 - 0.12 12.2 6.1 0.27 11.2 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2633) Phospholip_A2_1 PF00068.19 CBY32795.1 - 0.0062 17.0 0.7 0.0062 17.0 0.7 2.0 2 0 0 2 2 2 1 Phospholipase A2 T-box PF00907.22 CBY32796.1 - 5e-77 258.3 0.3 5e-77 258.3 0.3 2.3 2 0 0 2 2 2 1 T-box Tubulin_2 PF13809.6 CBY32796.1 - 0.19 10.8 2.1 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Tubulin like Trypsin PF00089.26 CBY32797.1 - 5.1e-25 88.6 0.2 1e-24 87.6 0.2 1.5 1 0 0 1 1 1 1 Trypsin CUB PF00431.20 CBY32797.1 - 1.1e-14 54.7 0.0 1.8e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 CUB domain WAK_assoc PF14380.6 CBY32797.1 - 0.057 14.2 0.2 0.29 11.9 0.0 2.3 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal Plectin PF00681.20 CBY32799.1 - 1.1e-21 76.5 0.0 1e-16 60.5 0.1 3.2 3 0 0 3 3 3 2 Plectin repeat T-box PF00907.22 CBY32800.1 - 1.9e-61 207.5 0.1 2.7e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 T-box G_glu_transpept PF01019.21 CBY32801.1 - 6.4e-147 490.4 0.0 7.4e-147 490.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PAT1 PF09770.9 CBY32802.1 - 2.9 6.0 9.4 3.4 5.8 9.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 T3SS_ATPase_C PF18269.1 CBY32803.1 - 0.075 12.9 0.0 0.075 12.9 0.0 1.0 1 0 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RIO1 PF01163.22 CBY32804.1 - 0.57 9.8 2.3 0.86 9.2 2.3 1.2 1 0 0 1 1 1 0 RIO1 family GRAM PF02893.20 CBY32805.1 - 1.2e-06 28.4 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 GRAM domain BBL5 PF07289.11 CBY32805.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CBY32805.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 PQ-loop PF04193.14 CBY32806.1 - 1.5e-20 72.7 7.4 5.3e-16 58.1 3.5 3.1 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CBY32806.1 - 0.00049 20.9 8.2 0.0075 17.1 6.6 2.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor Ferlin_C PF16165.5 CBY32806.1 - 0.2 11.6 2.4 0.21 11.5 1.1 1.7 1 1 0 1 1 1 0 Ferlin C-terminus 4HBT_2 PF13279.6 CBY32807.1 - 4.8e-06 27.1 0.0 0.023 15.2 0.0 2.3 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 CBY32807.1 - 0.00053 19.4 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DRY_EERY PF09750.9 CBY32808.1 - 3.1e-32 111.7 3.4 3.1e-32 111.7 3.4 5.2 3 2 1 4 4 4 1 Alternative splicing regulator ATP-synt_E PF05680.12 CBY32809.1 - 1e-08 35.4 0.1 1.3e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase E chain DUF4500 PF14937.6 CBY32810.1 - 1.3e-29 102.1 0.1 1.5e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4500) zf-Tim10_DDP PF02953.15 CBY32811.1 - 8.5e-14 51.0 3.3 8.5e-14 51.0 3.3 1.6 2 0 0 2 2 2 1 Tim10/DDP family zinc finger CLP1_P PF16575.5 CBY32812.1 - 2.1e-67 226.6 0.0 3.3e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBY32812.1 - 3e-29 101.1 0.0 5.2e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBY32812.1 - 8.9e-27 93.8 0.0 1.3e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 PduV-EutP PF10662.9 CBY32812.1 - 6.4e-05 22.7 0.0 0.1 12.3 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CBY32812.1 - 0.0021 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CBY32812.1 - 0.0079 16.2 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 CBY32812.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 CBY32812.1 - 0.051 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 CBY32812.1 - 0.054 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase FAM220 PF15487.6 CBY32813.1 - 0.6 9.7 8.8 0.83 9.2 8.8 1.3 1 0 0 1 1 1 0 FAM220 family FGE-sulfatase PF03781.16 CBY32814.1 - 1.1e-78 264.4 5.1 2e-78 263.6 5.1 1.4 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 HTH_39 PF14090.6 CBY32814.1 - 0.00067 19.4 0.2 0.3 10.8 0.0 3.6 2 1 0 3 3 3 1 Helix-turn-helix domain AhpC-TSA PF00578.21 CBY32814.1 - 0.39 10.7 4.0 9.7 6.1 0.0 4.3 3 2 1 5 5 5 0 AhpC/TSA family PPV_E2_C PF00511.17 CBY32814.1 - 1.7 8.9 3.1 61 3.9 0.1 3.2 3 0 0 3 3 3 0 E2 (early) protein, C terminal DUF883 PF05957.13 CBY32814.1 - 2.9 8.6 29.0 7 7.3 0.2 5.9 2 2 1 5 5 5 0 Bacterial protein of unknown function (DUF883) RdRP_1 PF00680.20 CBY32814.1 - 4.5 5.7 13.1 0.94 7.9 0.9 3.2 1 1 0 2 2 2 0 RNA dependent RNA polymerase FAD_binding_6 PF00970.24 CBY32815.1 - 3.1e-34 117.3 0.0 5.4e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBY32815.1 - 3.8e-31 107.9 0.0 1e-30 106.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY32815.1 - 7.3e-06 26.2 0.0 6.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain LysE PF01810.18 CBY32815.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 LysE type translocator Ldh_1_N PF00056.23 CBY32816.1 - 3.6e-36 124.4 0.1 5.2e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBY32816.1 - 2.4e-34 118.7 0.0 5.5e-34 117.5 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain PE-PPE PF08237.11 CBY32816.1 - 0.089 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Glycos_transf_2 PF00535.26 CBY32818.1 - 4.2e-26 91.8 0.0 7.5e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 CBY32818.1 - 2.3e-07 30.4 0.1 4.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 CBY32818.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_transf_64 PF09258.10 CBY32818.1 - 0.26 10.5 3.6 0.76 9.0 1.4 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain DUF2052 PF09747.9 CBY32820.1 - 1e-13 51.9 15.5 6.1e-12 46.1 15.5 2.3 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Glycos_transf_4 PF00953.21 CBY32821.1 - 3.8e-34 118.0 7.3 3.8e-34 118.0 7.3 1.8 3 0 0 3 3 3 1 Glycosyl transferase family 4 RabGAP-TBC PF00566.18 CBY32823.1 - 3.2e-46 157.7 0.0 8.5e-46 156.3 0.0 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CBY32823.1 - 2e-18 66.3 1.9 1.6e-09 37.6 0.5 2.8 2 1 0 2 2 2 2 GRAM domain DUF2301 PF10063.9 CBY32823.1 - 0.047 14.1 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FHA PF00498.26 CBY32824.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY32824.1 - 3.9e-05 23.9 0.0 0.0017 18.6 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LRR_4 PF12799.7 CBY32825.1 - 9.2e-11 41.8 7.6 6.4e-06 26.4 0.0 4.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY32825.1 - 2.3e-06 27.3 3.1 1.1e-05 25.1 0.3 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CBY32825.1 - 0.0045 16.5 1.0 0.024 14.2 0.1 2.4 1 1 1 2 2 2 1 Leucine-rich repeat DUF966 PF06136.13 CBY32825.1 - 0.023 14.4 4.2 0.032 14.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FoP_duplication PF13865.6 CBY32825.1 - 0.09 13.3 0.1 0.09 13.3 0.1 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 LRR_6 PF13516.6 CBY32825.1 - 0.13 12.4 0.1 50 4.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY32825.1 - 0.62 10.8 5.2 83 4.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat PDZ PF00595.24 CBY32826.1 - 5.9e-18 65.0 0.4 2.7e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY32826.1 - 5.7e-17 61.3 0.1 6.5e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY32826.1 - 1e-08 35.4 0.0 3e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY32826.1 - 0.0079 16.1 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain PMP22_Claudin PF00822.20 CBY32829.1 - 2.9e-07 30.5 4.5 2.9e-07 30.5 4.5 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family pEK499_p136 PF18736.1 CBY32830.1 - 0.066 12.8 1.2 0.092 12.4 1.2 1.3 1 0 0 1 1 1 0 HEPN pEK499 p136 Tricorn_PDZ PF14685.6 CBY32830.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain SHNi-TPR PF10516.9 CBY32831.1 - 0.16 11.4 2.9 6.9 6.2 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR Rhodanese PF00581.20 CBY32832.1 - 3.9e-11 43.4 0.0 4.3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain DnaJ PF00226.31 CBY32834.1 - 0.0023 18.0 1.3 0.0078 16.3 0.0 2.5 3 0 0 3 3 3 1 DnaJ domain RPT PF13446.6 CBY32834.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein VirJ PF06057.11 CBY32834.1 - 0.084 12.7 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1943 PF09172.11 CBY32834.1 - 0.2 10.9 2.7 0.29 10.3 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) UIM PF02809.20 CBY32834.1 - 0.23 11.5 2.3 1.8 8.6 0.8 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif OrfB_IS605 PF01385.19 CBY32834.1 - 4.1 7.6 6.6 2.6 8.3 1.9 2.1 2 0 0 2 2 2 0 Probable transposase CALCOCO1 PF07888.11 CBY32834.1 - 4.3 6.1 16.8 0.37 9.6 11.8 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like OmpH PF03938.14 CBY32834.1 - 8.5 6.7 18.5 12 6.2 14.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5401 PF17380.2 CBY32834.1 - 9.3 4.2 12.7 13 3.7 12.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF724 PF05266.14 CBY32834.1 - 9.6 6.0 17.1 0.85 9.4 12.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) WH1 PF00568.23 CBY32835.1 - 1.4e-18 66.8 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CBY32835.1 - 7.2e-08 32.0 0.5 1.3e-07 31.2 0.5 1.5 1 0 0 1 1 1 1 WH2 motif Ran_BP1 PF00638.18 CBY32835.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 RanBP1 domain Hyccin PF09790.9 CBY32836.1 - 1.5e-09 37.4 5.2 1.5e-05 24.3 3.1 2.5 1 1 1 2 2 2 2 Hyccin Birna_VP4 PF01768.16 CBY32836.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF667 PF05018.13 CBY32837.1 - 6.4e-56 189.0 0.9 7.1e-56 188.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) SGBP_B_XBD PF18329.1 CBY32837.1 - 0.027 14.4 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain MCM_bind PF09739.9 CBY32838.1 - 6.8e-70 236.1 4.2 8.5e-64 216.0 0.4 2.0 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor Aha1_N PF09229.11 CBY32838.1 - 0.12 12.6 1.7 8.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Serinc PF03348.15 CBY32839.1 - 5e-33 114.7 23.3 6.3e-33 114.3 23.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ASFV_L11L PF05293.11 CBY32839.1 - 0.001 19.4 0.7 0.0042 17.4 0.7 2.1 1 0 0 1 1 1 1 African swine fever virus (ASFV) L11L protein SCO1-SenC PF02630.14 CBY32841.1 - 2.4e-37 127.8 0.0 3.1e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBY32841.1 - 0.00067 19.9 0.2 0.0016 18.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like BRICHOS PF04089.14 CBY32841.1 - 0.031 14.5 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 BRICHOS domain UPF0154 PF03672.13 CBY32841.1 - 0.055 13.5 0.2 9.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Phage_30_3 PF08010.11 CBY32842.1 - 0.058 13.2 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 zf-C2H2_4 PF13894.6 CBY32842.1 - 0.068 14.0 37.9 7.4 7.7 0.1 8.1 7 1 0 7 7 7 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY32842.1 - 0.071 13.6 1.6 0.071 13.6 1.6 6.1 6 1 0 6 6 6 0 Zinc-finger double domain zf-C2H2 PF00096.26 CBY32842.1 - 0.16 12.5 0.2 0.16 12.5 0.2 7.8 8 2 0 8 8 8 0 Zinc finger, C2H2 type Zn_ribbon_SprT PF17283.2 CBY32842.1 - 0.17 11.8 0.0 0.17 11.8 0.0 4.8 5 0 0 5 5 5 0 SprT-like zinc ribbon domain zf-BED PF02892.15 CBY32842.1 - 0.41 10.7 27.0 0.27 11.3 0.2 6.0 3 2 2 5 5 5 0 BED zinc finger PyrI_C PF02748.15 CBY32842.1 - 1.9 8.5 14.3 4.3 7.3 0.2 4.5 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.7 CBY32842.1 - 2.7 8.1 18.1 0.083 12.9 2.8 3.9 2 1 0 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 CBY32842.1 - 3 8.0 10.5 2.6 8.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger domain WD40_alt PF14077.6 CBY32843.1 - 0.05 13.5 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Vps39_2 PF10367.9 CBY32844.1 - 0.011 16.1 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 RYDR_ITPR PF01365.21 CBY32844.1 - 0.015 14.8 0.1 0.034 13.6 0.1 1.6 1 1 0 1 1 1 0 RIH domain Vps39_2 PF10367.9 CBY32845.1 - 0.0035 17.8 0.0 0.0088 16.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 FapA PF03961.13 CBY32846.1 - 0.031 12.9 9.1 0.05 12.2 9.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A PEARLI-4 PF05278.12 CBY32846.1 - 0.033 13.8 10.1 0.06 12.9 10.1 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Ribosomal_S2 PF00318.20 CBY32846.1 - 0.069 12.4 3.4 0.15 11.3 3.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S2 DUF951 PF06107.11 CBY32846.1 - 0.1 12.6 0.3 15 5.6 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) NYD-SP28_assoc PF14775.6 CBY32846.1 - 0.11 12.6 0.7 0.11 12.6 0.7 3.3 3 2 0 3 3 3 0 Sperm tail C-terminal domain Striatin PF08232.12 CBY32846.1 - 0.12 13.0 21.0 0.27 11.8 6.3 3.2 3 1 0 3 3 3 0 Striatin family Fzo_mitofusin PF04799.13 CBY32846.1 - 0.14 11.7 5.7 0.27 10.8 5.7 1.5 1 0 0 1 1 1 0 fzo-like conserved region GAS PF13851.6 CBY32846.1 - 0.5 9.7 25.0 0.079 12.3 20.7 1.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 CBY32846.1 - 0.92 9.3 19.7 0.098 12.4 14.9 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cep57_MT_bd PF06657.13 CBY32846.1 - 1 9.8 13.0 6 7.4 2.4 3.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 CBY32846.1 - 4.6 7.3 27.4 0.46 10.5 19.8 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein KfrA_N PF11740.8 CBY32846.1 - 8 7.2 15.7 4.7 7.9 1.7 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term CorA PF01544.18 CBY32846.1 - 9.5 5.4 8.2 4.4 6.5 0.3 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Lectin_C PF00059.21 CBY32847.1 - 4.4e-36 123.9 23.7 3.3e-16 60.0 5.5 4.0 3 1 0 3 3 3 3 Lectin C-type domain Ion_trans PF00520.31 CBY32849.1 - 5.7e-13 48.7 16.8 7.5e-13 48.3 16.8 1.1 1 0 0 1 1 1 1 Ion transport protein LSM PF01423.22 CBY32850.1 - 4.8e-21 74.2 1.0 5.4e-21 74.0 1.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY32850.1 - 0.079 13.1 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CBY32850.1 - 0.084 13.0 0.2 0.12 12.4 0.2 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain WD40 PF00400.32 CBY32852.1 - 0.0031 18.3 8.4 6.8 7.7 0.7 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat CUB PF00431.20 CBY32853.1 - 3.6e-21 75.6 0.0 5.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 CUB domain SARAF PF06682.12 CBY32853.1 - 0.0013 18.4 1.1 0.0022 17.7 0.0 1.8 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis FliX PF10768.9 CBY32853.1 - 4.7 7.7 7.9 0.4 11.2 3.3 1.5 2 0 0 2 2 2 0 Class II flagellar assembly regulator Ank_2 PF12796.7 CBY32855.1 - 2e-21 76.4 0.0 1.7e-12 47.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY32855.1 - 6.2e-17 61.7 0.0 2.1e-06 28.2 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY32855.1 - 7e-14 50.6 0.0 0.011 16.2 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBY32855.1 - 8.2e-14 51.5 0.3 2.1e-06 27.9 0.0 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY32855.1 - 9.4e-14 51.2 0.3 0.0011 19.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF1515 PF07439.11 CBY32856.1 - 0.0035 17.4 0.1 0.0064 16.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) LapA_dom PF06305.11 CBY32856.1 - 0.018 14.8 0.9 0.03 14.1 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DnaJ PF00226.31 CBY32857.1 - 0.00076 19.6 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pup PF05639.11 CBY32857.1 - 0.1 13.5 0.7 0.23 12.4 0.6 1.5 2 0 0 2 2 2 0 Pup-like protein PriC PF07445.12 CBY32857.1 - 0.21 11.5 2.4 0.13 12.1 0.4 1.7 1 1 1 2 2 2 0 Primosomal replication protein priC STALD PF18185.1 CBY32859.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family BBP1_N PF15271.6 CBY32859.1 - 0.1 13.4 0.1 0.12 13.2 0.1 1.0 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein UPF0564 PF10595.9 CBY32861.1 - 4.4e-24 85.2 47.1 4.4e-24 85.2 47.1 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 bZIP_2 PF07716.15 CBY32862.1 - 5.3e-11 42.4 6.0 5.3e-11 42.4 6.0 2.7 1 1 1 3 3 3 1 Basic region leucine zipper Spc7 PF08317.11 CBY32862.1 - 1.3 7.9 16.8 1.8 7.4 16.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.32 CBY32863.1 - 1.7e-19 69.8 15.1 4.6e-07 30.4 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBY32863.1 - 1.3e-11 44.6 0.0 1.6e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBY32863.1 - 2.8e-07 30.7 3.1 0.00088 19.5 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain COG7 PF10191.9 CBY32864.1 - 1.1e-68 232.2 14.4 1.4e-68 231.9 14.4 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DUF5078 PF16877.5 CBY32864.1 - 0.026 15.0 0.2 0.069 13.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) Baculo_PEP_N PF04512.12 CBY32864.1 - 0.036 14.3 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Ribosomal_60s PF00428.19 CBY32864.1 - 0.082 13.5 1.6 0.96 10.1 0.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4283 PF14111.6 CBY32864.1 - 0.099 12.2 0.0 14 5.2 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4283) Tup_N PF08581.10 CBY32864.1 - 0.18 12.1 6.0 0.095 13.0 1.5 2.7 2 1 1 3 3 3 0 Tup N-terminal Rx_N PF18052.1 CBY32864.1 - 0.21 11.9 7.2 0.1 12.9 2.0 3.0 3 1 1 4 4 4 0 Rx N-terminal domain Mit_KHE1 PF10173.9 CBY32864.1 - 0.22 11.6 6.2 0.26 11.4 5.0 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF2250 PF10007.9 CBY32864.1 - 0.24 11.5 2.4 3.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HK97-gp10_like PF04883.12 CBY32864.1 - 0.24 12.4 1.4 1 10.4 1.4 2.4 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component BLOC1_2 PF10046.9 CBY32864.1 - 1.1 9.6 12.1 0.057 13.7 3.0 3.4 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 CBY32864.1 - 4.1 7.6 15.9 1.4 9.0 10.7 2.6 2 1 1 3 3 3 0 Tropomyosin like Cytochrom_B562 PF07361.11 CBY32864.1 - 9.1 7.0 12.3 16 6.2 0.5 3.3 2 1 1 3 3 3 0 Cytochrome b562 EzrA PF06160.12 CBY32865.1 - 0.00034 18.9 22.3 0.00044 18.5 22.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Atg14 PF10186.9 CBY32865.1 - 0.0014 17.8 21.8 0.0059 15.7 8.5 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 CBY32865.1 - 0.028 14.2 24.2 0.073 12.8 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 CBY32865.1 - 0.06 13.4 10.0 0.56 10.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 CBY32865.1 - 0.13 11.8 9.7 0.18 11.4 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RPW8 PF05659.11 CBY32865.1 - 0.55 9.9 11.5 0.83 9.3 3.1 2.4 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF730 PF05325.11 CBY32865.1 - 0.61 10.1 9.4 0.5 10.4 1.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF730) ISG65-75 PF11727.8 CBY32865.1 - 0.7 9.1 15.3 0.25 10.5 7.5 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein FAM76 PF16046.5 CBY32865.1 - 1 8.6 16.0 2 7.7 16.0 1.5 1 1 0 1 1 1 0 FAM76 protein YabA PF06156.13 CBY32865.1 - 1.2 9.8 20.1 3.1 8.5 14.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 CBY32865.1 - 3.5 7.8 21.7 0.17 12.0 2.4 3.4 1 1 1 3 3 3 0 bZIP transcription factor SKA1 PF07160.12 CBY32865.1 - 4.2 7.1 21.9 0.46 10.3 12.3 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Laminin_II PF06009.12 CBY32865.1 - 4.9 7.2 19.5 10 6.1 4.5 2.2 1 1 1 2 2 2 0 Laminin Domain II UPF0242 PF06785.11 CBY32865.1 - 5.4 7.1 30.7 1.1 9.4 26.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MPS2 PF17060.5 CBY32865.1 - 5.6 6.1 16.1 11 5.2 16.1 1.3 1 1 0 1 1 1 0 Monopolar spindle protein 2 FliD_N PF02465.18 CBY32865.1 - 5.9 7.6 11.3 17 6.1 1.9 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF2205 PF10224.9 CBY32865.1 - 7.1 6.7 17.0 3.3 7.8 5.5 3.0 2 1 1 3 3 3 0 Short coiled-coil protein SET PF00856.28 CBY32866.1 - 5.7e-18 65.9 2.7 6e-18 65.8 0.7 2.2 2 0 0 2 2 2 1 SET domain preSET_CXC PF18264.1 CBY32866.1 - 1.5e-10 41.4 16.6 1.5e-10 41.4 16.6 3.9 3 1 1 4 4 4 1 CXC domain DDA1 PF10172.9 CBY32866.1 - 0.023 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase Pkinase PF00069.25 CBY32867.1 - 9.2e-36 123.6 0.2 3.1e-35 121.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32867.1 - 6.1e-18 65.0 0.0 5.6e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 Protein tyrosine kinase DUF842 PF05811.13 CBY32868.1 - 0.19 11.5 0.7 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF3775 PF12616.8 CBY32869.1 - 0.00034 20.6 0.1 0.00089 19.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3775) V-ATPase_G PF03179.15 CBY32870.1 - 1.7e-30 105.7 16.0 1.9e-30 105.5 16.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NINJA_B PF16136.5 CBY32870.1 - 0.05 14.0 5.1 0.064 13.6 5.1 1.1 1 0 0 1 1 1 0 Putative nuclear localisation signal vATP-synt_E PF01991.18 CBY32870.1 - 0.087 12.2 11.1 0.1 12.0 11.1 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF1690 PF07956.11 CBY32870.1 - 0.28 11.6 8.2 0.45 10.9 8.2 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) GA PF01468.17 CBY32870.1 - 0.68 10.3 9.0 0.33 11.2 0.7 2.9 3 0 0 3 3 3 0 GA module OmpH PF03938.14 CBY32870.1 - 0.7 10.2 17.6 0.9 9.9 17.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CBY32870.1 - 2 7.7 9.2 2.4 7.4 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CBY32870.1 - 3.3 6.7 8.0 4 6.4 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V-ATPase_G_2 PF16999.5 CBY32870.1 - 3.3 8.2 17.2 5.3 7.5 17.2 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit UPF0242 PF06785.11 CBY32870.1 - 5.2 7.1 10.5 7 6.7 10.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATP-synt_B PF00430.18 CBY32870.1 - 9.5 6.3 20.1 2.6 8.1 16.2 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DnaJ PF00226.31 CBY32871.1 - 2.1e-19 69.4 0.1 7.5e-19 67.6 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 CBY32871.1 - 6e-15 55.2 1.4 2.9e-07 30.6 0.6 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY32871.1 - 0.0003 21.0 6.1 0.21 11.9 0.7 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Presenilin PF01080.17 CBY32871.1 - 1.7 7.4 12.0 0.51 9.1 3.8 2.3 2 0 0 2 2 2 0 Presenilin ELM2 PF01448.24 CBY32871.1 - 2.5 8.9 0.0 2.5 8.9 0.0 3.2 2 1 0 2 2 2 0 ELM2 domain PUF PF00806.19 CBY32872.1 - 5.8e-07 28.8 0.0 4.8e-05 22.8 0.0 3.9 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat DUF1400 PF07176.11 CBY32872.1 - 0.057 13.7 0.0 7.9 6.8 0.0 3.3 3 1 1 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) HECT PF00632.25 CBY32873.1 - 1.2e-88 297.5 0.0 2.8e-88 296.4 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CBY32873.1 - 0.00015 21.2 0.0 0.00039 19.9 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Gal-3-0_sulfotr PF06990.11 CBY32874.1 - 1.8e-30 106.1 2.5 2.7e-30 105.5 2.5 1.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Gal-3-0_sulfotr PF06990.11 CBY32875.1 - 3.3e-36 125.0 0.2 3.6e-36 124.9 0.2 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY32875.1 - 2.3e-05 24.4 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY32875.1 - 0.073 12.5 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain zf-RING_2 PF13639.6 CBY32876.1 - 6.2e-06 26.5 3.1 1.1e-05 25.7 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY32876.1 - 3.6e-05 23.7 1.2 7e-05 22.8 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY32876.1 - 5.4e-05 23.1 3.6 9.5e-05 22.3 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY32876.1 - 0.00058 19.7 1.9 0.0011 18.7 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY32876.1 - 0.0013 18.6 3.0 0.0039 17.0 3.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY32876.1 - 0.034 13.9 2.8 0.068 12.9 2.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 CBY32876.1 - 0.11 12.4 2.2 0.23 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PhoQ_Sensor PF08918.10 CBY32876.1 - 0.17 11.7 0.8 0.28 11.0 0.8 1.3 1 0 0 1 1 1 0 PhoQ Sensor zf-C3HC4_4 PF15227.6 CBY32876.1 - 0.18 12.0 3.8 0.34 11.1 0.4 2.5 1 1 0 2 2 2 0 zinc finger of C3HC4-type, RING C1_2 PF03107.16 CBY32876.1 - 0.24 11.7 3.4 0.38 11.1 3.4 1.4 1 0 0 1 1 1 0 C1 domain zf-rbx1 PF12678.7 CBY32876.1 - 0.31 11.4 5.5 0.9 9.9 5.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 CBY32876.1 - 0.34 11.0 6.2 0.86 9.7 6.2 1.7 1 0 0 1 1 1 0 PHD-finger ALMT PF11744.8 CBY32876.1 - 0.44 9.3 4.1 0.07 12.0 0.4 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter zf-CpG_bind_C PF12269.8 CBY32876.1 - 1.3 8.8 16.5 0.5 10.1 10.2 2.1 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Homeodomain PF00046.29 CBY32878.1 - 1.5e-20 72.8 1.6 1.5e-20 72.8 1.6 2.4 3 0 0 3 3 3 1 Homeodomain TPT PF03151.16 CBY32879.1 - 0.00043 19.7 12.7 0.00053 19.4 12.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Trep_Strep PF09605.10 CBY32879.1 - 0.39 10.7 14.3 0.21 11.5 5.9 2.3 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) 7tm_1 PF00001.21 CBY32880.1 - 2.2e-15 56.7 1.2 2.9e-15 56.3 1.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY32880.1 - 0.019 14.1 6.1 0.012 14.8 3.6 1.7 1 1 1 2 2 2 0 Taste receptor protein (TAS2R) DUF1129 PF06570.11 CBY32880.1 - 0.077 12.5 0.5 0.11 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YesK PF14150.6 CBY32880.1 - 0.42 10.8 5.1 0.15 12.3 1.3 2.2 2 1 1 3 3 3 0 YesK-like protein DUF5316 PF17247.2 CBY32880.1 - 2.4 8.2 6.3 2.1 8.4 0.3 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5316) 7tm_1 PF00001.21 CBY32881.1 - 1.4e-09 37.7 1.4 1.6e-09 37.5 1.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY32881.1 - 0.0017 17.8 2.0 0.0018 17.7 2.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SNF PF00209.18 CBY32883.1 - 6e-138 460.8 27.2 7.4e-138 460.5 27.2 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Kelch_1 PF01344.25 CBY32886.1 - 1.2e-05 24.7 0.7 0.32 10.6 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY32886.1 - 0.00042 20.5 0.2 0.015 15.6 0.0 3.0 1 1 2 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CBY32886.1 - 0.00061 19.7 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY32886.1 - 0.088 13.1 0.0 9.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY32886.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY32886.1 - 0.17 11.9 1.2 0.91 9.6 0.0 2.7 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1945 PF09178.10 CBY32887.1 - 0.044 14.0 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) QIL1 PF15884.5 CBY32888.1 - 0.083 13.5 0.0 37 5.0 0.0 3.2 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 UCH PF00443.29 CBY32889.1 - 2.2e-06 27.4 0.3 9.2e-06 25.3 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PRESAN PF09687.10 CBY32889.1 - 1.7 9.2 13.5 0.68 10.5 1.3 2.9 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Ank_4 PF13637.6 CBY32890.1 - 1.8e-07 31.6 0.0 0.014 16.0 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY32890.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY32890.1 - 1.2e-05 25.4 0.0 0.049 14.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Get5_C PF18514.1 CBY32890.1 - 0.0058 16.3 0.5 0.03 14.0 0.0 2.4 3 0 0 3 3 3 1 Get5 C-terminal domain Ank_3 PF13606.6 CBY32890.1 - 0.0075 16.7 0.0 1.3 9.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 CBY32890.1 - 0.072 13.6 0.0 0.63 10.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat TAF PF02969.17 CBY32892.1 - 0.021 15.0 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Enkurin PF13864.6 CBY32893.1 - 3.7e-26 91.4 2.3 3.7e-26 91.4 2.3 1.8 2 0 0 2 2 2 1 Calmodulin-binding Cul7 PF11515.8 CBY32893.1 - 0.096 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 C2 PF00168.30 CBY32894.1 - 0.00013 22.2 0.0 0.0027 18.0 0.0 2.6 3 0 0 3 3 3 1 C2 domain Pex24p PF06398.11 CBY32894.1 - 0.00073 18.6 0.8 0.0013 17.8 0.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 CBY32894.1 - 0.011 15.6 0.1 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal ArsP_1 PF03773.13 CBY32894.1 - 0.074 12.2 0.5 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 Predicted permease Lyase_8_N PF08124.11 CBY32894.1 - 0.12 11.3 0.2 0.58 9.0 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Ribonuc_2-5A PF06479.12 CBY32895.1 - 6.6e-08 32.8 1.6 1.7e-07 31.4 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease 2-5A pEK499_p136 PF18736.1 CBY32895.1 - 0.001 18.7 0.0 0.0034 17.0 0.0 1.9 1 0 0 1 1 1 1 HEPN pEK499 p136 Gal-3-0_sulfotr PF06990.11 CBY32896.1 - 3.8e-71 240.1 0.0 4.9e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY32896.1 - 0.00056 19.9 0.3 0.038 13.9 0.0 2.7 3 1 0 3 3 3 2 Sulfotransferase family Nuc_sug_transp PF04142.15 CBY32897.1 - 7e-25 87.8 23.9 1.7e-24 86.6 23.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY32897.1 - 0.0048 17.1 26.6 0.017 15.3 2.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3760 PF12586.8 CBY32897.1 - 0.15 12.2 1.5 1.3 9.3 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) AA_permease_2 PF13520.6 CBY32898.1 - 2.3e-55 188.2 46.2 2.6e-55 188.0 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY32898.1 - 2.6e-22 79.1 36.9 3.4e-22 78.7 36.9 1.2 1 0 0 1 1 1 1 Amino acid permease SMC_N PF02463.19 CBY32899.1 - 4.7e-30 104.7 32.3 9.9e-28 97.1 32.3 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBY32899.1 - 5.3e-17 62.2 0.0 1.6e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CBY32899.1 - 7.1e-12 46.2 19.0 7.1e-12 46.2 19.0 3.9 1 1 2 3 3 3 1 AAA domain AAA_15 PF13175.6 CBY32899.1 - 4e-08 33.4 13.1 4e-08 33.4 13.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CBY32899.1 - 2.8e-05 24.1 2.4 3.6e-05 23.7 0.2 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY32899.1 - 0.00025 20.7 0.0 0.00075 19.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 CBY32899.1 - 6.7 4.1 48.0 0.37 8.3 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TTL PF03133.15 CBY32900.1 - 4e-25 88.6 0.3 5.8e-25 88.0 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TTL PF03133.15 CBY32901.1 - 1.5e-14 53.9 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family HMG_box PF00505.19 CBY32902.1 - 4e-22 78.4 3.9 7.2e-22 77.6 3.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY32902.1 - 4.9e-08 33.4 4.1 1.1e-07 32.3 4.1 1.5 1 0 0 1 1 1 1 HMG-box domain NINJA_B PF16136.5 CBY32902.1 - 0.021 15.2 2.4 0.056 13.8 2.4 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal Ank_4 PF13637.6 CBY32903.1 - 1.8e-25 89.0 0.3 3.9e-09 36.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY32903.1 - 7.7e-24 84.1 0.2 8.1e-15 55.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY32903.1 - 2.5e-21 75.1 0.1 5.4e-06 26.6 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CBY32903.1 - 2.5e-18 64.3 0.0 0.00047 20.4 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY32903.1 - 6.7e-14 51.8 0.1 3.1e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF1843 PF08898.10 CBY32903.1 - 0.15 12.6 1.2 9.3 6.8 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) PC_rep PF01851.22 CBY32903.1 - 0.16 12.4 0.1 3.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Proteasome/cyclosome repeat SlyX PF04102.12 CBY32903.1 - 1.4 9.6 6.4 3.6 8.3 6.4 1.7 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 CBY32903.1 - 4.5 7.1 7.2 2.9 7.7 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator Dynamin_M PF01031.20 CBY32904.1 - 3.5e-84 282.4 0.1 7.3e-84 281.4 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY32904.1 - 3.7e-45 154.0 0.4 7.1e-45 153.1 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CBY32904.1 - 9.3e-24 83.4 2.1 9.3e-24 83.4 2.1 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CBY32904.1 - 3.7e-05 23.8 0.0 0.00013 22.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C2H2_4 PF13894.6 CBY32905.1 - 8.6e-15 54.2 70.5 0.018 15.8 4.0 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY32905.1 - 3.1e-14 52.5 73.7 0.0014 19.0 0.3 9.6 9 0 0 9 9 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY32905.1 - 9.8e-11 41.6 9.3 3.7e-08 33.4 0.5 9.5 10 1 0 10 10 9 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY32905.1 - 2.9e-07 30.1 35.4 0.00059 19.5 3.9 6.0 6 0 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CBY32905.1 - 0.00045 20.1 0.8 0.013 15.5 0.1 9.0 9 0 0 9 9 9 3 C2H2-type zinc finger zf_C2H2_10 PF18414.1 CBY32905.1 - 0.016 14.7 0.6 8.8 6.0 0.2 3.2 2 0 0 2 2 2 0 C2H2 type zinc-finger Zn_Tnp_IS1595 PF12760.7 CBY32905.1 - 0.032 14.2 29.3 0.24 11.4 0.0 5.1 5 0 0 5 5 5 0 Transposase zinc-ribbon domain DUF2321 PF10083.9 CBY32905.1 - 0.2 11.3 0.1 0.2 11.3 0.1 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) Zn-C2H2_12 PF18112.1 CBY32905.1 - 1.4 9.5 0.0 1.4 9.5 0.0 6.0 8 0 0 8 8 8 0 Autophagy receptor zinc finger-C2H2 domain YacG PF03884.14 CBY32905.1 - 2.8 7.7 7.3 4.2 7.2 3.6 2.9 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG DUF1610 PF07754.11 CBY32905.1 - 9.5 6.3 9.4 13 5.9 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) PCNA_C PF02747.15 CBY32906.1 - 1.2e-53 180.7 0.1 5.5e-53 178.5 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY32906.1 - 3e-48 162.7 3.0 4.8e-48 162.1 3.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 CBY32906.1 - 1.9e-09 37.0 0.1 3.4e-08 32.9 0.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CBY32906.1 - 2.5e-06 27.2 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBY32906.1 - 0.013 14.6 0.1 0.021 14.0 0.1 1.5 1 1 0 1 1 1 0 Hus1-like protein MKRN1_C PF15815.5 CBY32906.1 - 0.046 14.1 1.4 0.21 12.0 0.3 2.3 2 1 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal GTP_EFTU PF00009.27 CBY32907.1 - 8.2e-44 149.5 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY32907.1 - 3.8e-23 81.9 0.1 1.1e-22 80.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain SAYSvFN PF10260.9 CBY32907.1 - 8.7e-17 60.8 0.6 1.9e-16 59.7 0.6 1.5 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) GTP_EFTU_D2 PF03144.25 CBY32907.1 - 4.9e-08 33.3 0.7 1.5e-07 31.7 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY32907.1 - 0.0029 17.7 0.0 0.0085 16.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase LPD34 PF18852.1 CBY32907.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 PAM2 PF07145.15 CBY32907.1 - 0.078 12.7 9.6 0.074 12.8 1.5 3.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region FeoB_N PF02421.18 CBY32907.1 - 0.13 11.8 0.1 1.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B FAP PF07174.11 CBY32907.1 - 0.56 9.6 13.5 0.85 9.0 13.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) eIF3_subunit PF08597.10 CBY32907.1 - 5.4 6.9 11.7 12 5.7 11.7 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit LrgA PF03788.14 CBY32909.1 - 0.017 15.1 1.1 0.048 13.6 1.1 1.7 1 0 0 1 1 1 0 LrgA family DUF3487 PF11990.8 CBY32909.1 - 0.078 12.9 3.5 0.78 9.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) ATP-grasp_6 PF18419.1 CBY32910.1 - 0.067 12.8 0.3 3.4 7.4 0.1 3.0 2 0 0 2 2 2 0 ATP-grasp-like domain SlyX PF04102.12 CBY32910.1 - 0.28 11.8 0.1 0.28 11.8 0.1 8.9 8 3 2 10 10 10 0 SlyX Fez1 PF06818.15 CBY32910.1 - 1.6 9.1 60.4 0.31 11.5 11.3 5.5 1 1 4 5 5 5 0 Fez1 Trimer_CC PF08954.11 CBY32910.1 - 5.8 6.5 17.3 0.059 12.9 0.5 5.2 5 0 0 5 5 5 0 Trimerisation motif Ras PF00071.22 CBY32913.1 - 1.2e-31 109.5 0.0 2.3e-28 98.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CBY32913.1 - 1.6e-16 60.6 0.0 2.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY32913.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GSHPx PF00255.19 CBY32914.1 - 5.4e-20 71.0 0.0 6.9e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DNA_pol_B_exo1 PF03104.19 CBY32914.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain GSHPx PF00255.19 CBY32915.1 - 9.5e-05 21.9 0.1 0.00011 21.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase zf-met PF12874.7 CBY32916.1 - 2.8e-05 24.3 1.0 7.6e-05 23.0 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type RNase_T PF00929.24 CBY32916.1 - 2.9e-05 24.7 0.9 0.00024 21.7 0.1 2.6 2 1 0 2 2 2 1 Exonuclease zf-C2H2_jaz PF12171.8 CBY32916.1 - 0.00018 21.7 0.3 0.00045 20.4 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding UQ_con PF00179.26 CBY32916.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1126 PF06565.12 CBY32918.1 - 7.8e-86 282.8 0.6 2.2e-28 98.1 0.0 3.9 3 1 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 CBY32918.1 - 0.021 15.2 0.2 14 6.2 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG DnaJ_C PF01556.18 CBY32919.1 - 2e-29 102.6 0.0 2.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY32919.1 - 2.1e-19 69.4 0.0 3.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBY32919.1 - 1.4e-05 25.3 10.0 4.4e-05 23.8 10.0 1.9 1 1 0 1 1 1 1 DnaJ central domain Prp19 PF08606.11 CBY32920.1 - 5.1e-18 64.8 0.8 1e-17 63.8 0.8 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CBY32920.1 - 2.7e-16 59.7 1.1 3.7e-07 30.7 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat U-box PF04564.15 CBY32920.1 - 3e-05 24.1 0.0 6.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain ANAPC4_WD40 PF12894.7 CBY32920.1 - 0.0016 18.7 0.1 0.0046 17.2 0.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain zf-NOSIP PF15906.5 CBY32920.1 - 0.0096 16.0 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein tRNA_bind_2 PF13725.6 CBY32920.1 - 0.015 15.0 1.4 0.022 14.5 1.4 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain Pex19 PF04614.12 CBY32920.1 - 0.031 14.0 2.2 0.043 13.6 2.2 1.3 1 0 0 1 1 1 0 Pex19 protein family WD40_like PF17005.5 CBY32920.1 - 0.045 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain UPF0449 PF15136.6 CBY32920.1 - 0.52 10.8 4.4 0.45 11.0 1.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TSNAXIP1_N PF15739.5 CBY32920.1 - 2.4 8.6 5.9 0.91 9.9 2.0 2.1 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Cadherin PF00028.17 CBY32921.1 - 3.6e-05 24.1 1.9 1 9.8 0.0 5.1 4 2 0 4 4 4 2 Cadherin domain Cadherin_3 PF16184.5 CBY32921.1 - 0.0035 17.3 0.3 0.65 10.0 0.0 2.7 2 0 0 2 2 2 2 Cadherin-like Choline_kinase PF01633.20 CBY32922.1 - 1.1e-47 162.4 0.1 2e-47 161.5 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY32922.1 - 7.3e-10 39.2 0.0 1.5e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY32922.1 - 3.2e-05 23.4 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase GST_C_3 PF14497.6 CBY32923.1 - 1.3e-08 35.0 0.2 2.1e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY32923.1 - 5.8e-05 23.4 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY32923.1 - 0.00063 19.9 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY32923.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FTCD_C PF04961.12 CBY32923.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase GST_C_3 PF14497.6 CBY32924.1 - 4.7e-06 26.7 0.1 8.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_1 PF00036.32 CBY32924.1 - 0.00015 21.1 4.2 0.00053 19.3 0.1 3.4 3 0 0 3 3 3 1 EF hand GST_C PF00043.25 CBY32924.1 - 0.00089 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_6 PF13405.6 CBY32924.1 - 0.0015 18.3 1.5 0.0033 17.2 0.1 2.5 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY32924.1 - 0.0018 18.7 1.3 0.09 13.2 0.5 2.4 2 0 0 2 2 2 1 EF-hand domain pair GST_N PF02798.20 CBY32924.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain COX16 PF14138.6 CBY32924.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 LCCL PF03815.19 CBY32925.1 - 1.4e-09 37.9 0.0 3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.25 CBY32925.1 - 6.5e-09 36.0 0.0 1.4e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_3 PF13415.6 CBY32926.1 - 0.0051 17.1 0.0 0.28 11.5 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY32926.1 - 0.034 13.8 0.1 12 5.5 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY32926.1 - 0.061 13.3 0.6 4.3 7.4 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Epimerase PF01370.21 CBY32927.1 - 1.4e-45 155.7 0.0 1.9e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBY32927.1 - 6.3e-40 137.6 0.0 8.7e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CBY32927.1 - 6.5e-15 54.9 0.0 1.3e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBY32927.1 - 5.2e-09 36.2 0.0 1.1e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CBY32927.1 - 1e-07 31.4 0.0 2.2e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CBY32927.1 - 1.8e-07 30.6 0.0 4.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBY32927.1 - 7.1e-07 28.6 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CBY32927.1 - 0.059 12.8 0.2 0.3 10.5 0.2 2.2 1 1 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 CBY32927.1 - 0.14 12.4 0.0 2.9 8.2 0.0 2.3 1 1 0 1 1 1 0 TrkA-N domain Isochorismatase PF00857.20 CBY32927.1 - 0.15 12.2 0.0 1.3 9.2 0.0 2.3 3 0 0 3 3 3 0 Isochorismatase family UDPG_MGDP_dh_N PF03721.14 CBY32927.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.10 CBY32927.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 KR domain EGF_3 PF12947.7 CBY32928.1 - 1.6e-09 37.8 11.6 2.2e-06 27.8 0.2 8.5 7 1 1 9 9 9 5 EGF domain EGF PF00008.27 CBY32928.1 - 0.00044 20.5 61.9 0.14 12.5 2.4 9.5 8 3 1 9 9 9 5 EGF-like domain EGF_MSP1_1 PF12946.7 CBY32928.1 - 0.00053 20.0 6.5 0.00053 20.0 6.5 8.1 9 0 0 9 9 9 2 MSP1 EGF domain 1 PAS_9 PF13426.7 CBY32928.1 - 0.032 14.5 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 PAS domain HLH PF00010.26 CBY32929.1 - 1.5e-10 40.9 5.5 1.5e-10 40.9 5.5 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CUB PF00431.20 CBY32930.1 - 6.4e-12 45.8 0.1 8.6e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 CUB domain zf-RING_5 PF14634.6 CBY32931.1 - 9.2e-05 22.3 9.4 0.00016 21.6 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY32931.1 - 0.025 14.6 5.6 0.078 13.0 5.7 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY32931.1 - 0.091 12.6 7.6 0.19 11.6 7.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY32931.1 - 0.37 11.2 9.1 2.3 8.6 9.6 2.0 1 1 1 2 2 2 0 Ring finger domain FYVE PF01363.21 CBY32931.1 - 0.38 10.9 6.8 0.73 10.0 6.8 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-HIT PF04438.16 CBY32931.1 - 0.53 10.2 0.1 0.53 10.2 0.1 3.2 2 1 1 3 3 3 0 HIT zinc finger zf-C3HC4_2 PF13923.6 CBY32931.1 - 1.9 8.4 12.2 17 5.4 12.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY32931.1 - 3.7 7.5 10.5 23 5.0 10.6 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phage_30_3 PF08010.11 CBY32933.1 - 0.2 11.5 3.3 0.35 10.7 0.8 2.5 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 BSD PF03909.17 CBY32933.1 - 4.3 7.4 11.8 0.85 9.7 0.3 5.0 4 0 0 4 4 4 0 BSD domain zf-C2H2 PF00096.26 CBY32934.1 - 2.3e-11 43.5 14.8 0.00065 20.0 1.7 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY32934.1 - 1.1e-09 38.2 15.0 0.0013 19.4 1.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY32934.1 - 9.2e-09 35.1 10.5 0.14 12.2 0.2 4.4 3 1 1 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY32934.1 - 0.00043 20.5 16.2 0.029 14.7 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY32934.1 - 0.0012 19.2 0.5 0.0012 19.2 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-BED PF02892.15 CBY32934.1 - 0.0039 17.2 1.7 1.6 8.8 0.0 2.7 2 1 0 2 2 2 2 BED zinc finger LIM PF00412.22 CBY32934.1 - 0.0094 16.2 5.4 0.06 13.6 0.7 2.6 2 1 0 2 2 2 1 LIM domain FOXP-CC PF16159.5 CBY32934.1 - 0.25 12.0 1.8 3.3 8.4 0.1 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CBY32934.1 - 0.53 10.8 12.9 2.1 8.9 0.6 4.2 5 0 0 5 5 4 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 CBY32934.1 - 1.4 9.3 5.0 12 6.3 5.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon C1_2 PF03107.16 CBY32934.1 - 6.7 7.1 7.2 25 5.3 0.1 2.8 2 1 0 2 2 2 0 C1 domain Zn-ribbon_8 PF09723.10 CBY32934.1 - 8.7 6.6 6.9 7 6.9 0.6 2.9 3 0 0 3 3 3 0 Zinc ribbon domain DegQ PF08181.11 CBY32935.1 - 0.011 15.8 2.9 1.1 9.4 0.1 3.4 3 0 0 3 3 3 0 DegQ (SacQ) family ADIP PF11559.8 CBY32935.1 - 0.65 10.1 23.5 2.2 8.4 14.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.9 CBY32935.1 - 2.1 7.7 24.2 0.81 9.0 10.0 2.9 1 1 2 3 3 3 0 Clusterin-associated protein-1 FUSC PF04632.12 CBY32935.1 - 2.6 6.5 3.2 17 3.8 2.6 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 CBY32935.1 - 3.1 8.2 23.8 42 4.5 21.9 2.6 1 1 0 1 1 1 0 Fez1 TBCC_N PF16752.5 CBY32935.1 - 3.3 8.2 12.2 0.22 11.9 0.4 3.3 2 1 2 4 4 4 0 Tubulin-specific chaperone C N-terminal domain FKBP_C PF00254.28 CBY32936.1 - 1.6e-33 114.9 0.0 2e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CTNNBL PF08216.11 CBY32937.1 - 2.2e-29 101.7 1.2 2.2e-29 101.7 1.2 2.5 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear PDCD2_C PF04194.13 CBY32937.1 - 0.0074 16.4 3.6 0.021 14.9 3.6 1.7 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain RIH_assoc PF08454.11 CBY32937.1 - 0.011 15.5 0.5 1.5 8.7 0.2 3.3 2 1 0 2 2 2 0 RyR and IP3R Homology associated Ccdc124 PF06244.12 CBY32938.1 - 7.4e-09 36.2 28.4 3.5e-05 24.3 28.4 2.6 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Ribosomal_S9 PF00380.19 CBY32939.1 - 9.6e-15 55.2 0.3 6.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein S9/S16 SelR PF01641.18 CBY32940.1 - 0.003 17.6 1.0 0.022 14.8 0.7 2.4 1 1 0 1 1 1 1 SelR domain ELFV_dehydrog_N PF02812.18 CBY32942.1 - 3.1e-57 192.0 0.1 6.2e-57 191.1 0.1 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CBY32942.1 - 1.7e-48 165.5 0.0 7.1e-46 156.9 0.0 2.4 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HSP20 PF00011.21 CBY32943.1 - 0.00028 21.0 0.6 0.00051 20.2 0.6 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Nucleoporin_FG PF13634.6 CBY32943.1 - 0.11 13.3 2.9 0.23 12.3 2.9 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region 2OG-FeII_Oxy_2 PF13532.6 CBY32944.1 - 2.3e-05 24.7 0.0 7.5e-05 23.0 0.0 1.7 1 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3898 PF13037.6 CBY32944.1 - 0.084 13.0 0.1 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3898) DHODB_Fe-S_bind PF10418.9 CBY32944.1 - 0.16 11.8 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 2OG-FeII_Oxy PF03171.20 CBY32944.1 - 0.17 12.4 0.0 0.75 10.3 0.0 2.1 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3656 PF12392.8 CBY32944.1 - 0.55 10.9 3.6 1.5 9.5 2.8 2.1 2 0 0 2 2 2 0 Collagenase TMEM214 PF10151.9 CBY32944.1 - 6.8 5.0 10.8 10 4.5 10.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator D123 PF07065.14 CBY32945.1 - 4.2e-61 206.8 0.1 4.8e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 CBY32945.1 - 0.049 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 RVT_1 PF00078.27 CBY32946.1 - 2.2e-27 96.0 0.0 4.7e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spore_GerQ PF09671.10 CBY32948.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) DHODB_Fe-S_bind PF10418.9 CBY32949.1 - 0.078 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B bMG3 PF11974.8 CBY32949.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain TMEM214 PF10151.9 CBY32949.1 - 3.5 6.0 11.2 5.2 5.4 11.2 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator D123 PF07065.14 CBY32950.1 - 1.9e-63 214.5 0.2 2.2e-63 214.2 0.2 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 CBY32950.1 - 0.058 13.4 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 DUF2805 PF10985.8 CBY32950.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Cupin_8 PF13621.6 CBY32951.1 - 8.8e-55 186.2 1.3 1.2e-54 185.7 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBY32951.1 - 0.0061 17.0 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Dynein_C PF18199.1 CBY32953.1 - 8.3e-61 205.9 0.0 1.2e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY32953.1 - 2.3e-32 112.1 2.1 2.5e-32 112.0 0.3 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CBY32953.1 - 0.00093 18.8 0.0 0.0023 17.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region Gelsolin PF00626.22 CBY32954.1 - 1.3e-14 53.8 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat JIP_LZII PF16471.5 CBY32954.1 - 0.059 13.5 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Sugar_tr PF00083.24 CBY32955.1 - 5.5e-110 368.3 21.8 6.6e-110 368.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY32955.1 - 3.6e-21 75.5 22.8 6.4e-21 74.7 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Neur_chan_LBD PF02931.23 CBY32958.1 - 1.1e-41 142.7 0.1 1.4e-41 142.4 0.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY32958.1 - 5.8e-20 72.4 2.4 8.3e-20 71.9 2.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region ig PF00047.25 CBY32959.1 - 0.11 12.7 0.1 0.77 10.0 0.1 2.2 1 1 0 1 1 1 0 Immunoglobulin domain RNase_PH PF01138.21 CBY32963.1 - 1.4e-33 116.2 0.2 2.6e-33 115.3 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RhoGAP PF00620.27 CBY32964.1 - 4.4e-28 98.0 0.0 1.3e-27 96.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 CBY32964.1 - 2.2e-17 63.5 0.1 4.5e-16 59.3 0.0 2.6 2 0 0 2 2 2 1 MyTH4 domain WW PF00397.26 CBY32964.1 - 9.5e-07 28.8 1.4 7.2e-05 22.8 1.6 2.6 2 0 0 2 2 2 1 WW domain RhoGAP PF00620.27 CBY32965.1 - 9.9e-28 96.9 0.0 1.7e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain COMP PF11598.8 CBY32965.1 - 0.079 13.4 0.1 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF3439 PF11921.8 CBY32966.1 - 0.0017 18.3 2.1 0.002 18.1 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DHHC PF01529.20 CBY32968.1 - 0.03 14.4 2.9 0.11 12.6 1.2 2.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase Jagunal PF07086.12 CBY32968.1 - 0.1 12.7 0.4 0.1 12.7 0.4 1.5 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis Ion_trans PF00520.31 CBY32969.1 - 2.6e-31 108.7 9.6 3.8e-31 108.2 9.6 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY32969.1 - 4.5e-11 42.7 0.0 8.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 CBY32969.1 - 1e-10 41.4 0.2 1e-10 41.4 0.2 2.9 4 0 0 4 4 4 1 Ion channel Kinesin PF00225.23 CBY32970.1 - 1.2e-97 326.8 3.7 1.2e-97 326.8 3.7 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY32970.1 - 6.7e-19 68.3 2.3 3.5e-18 66.0 0.2 3.1 2 1 0 2 2 2 1 Microtubule binding FHA PF00498.26 CBY32970.1 - 3.1e-06 27.5 0.6 0.00016 21.9 0.3 2.9 2 0 0 2 2 2 1 FHA domain DUF313 PF03754.13 CBY32970.1 - 0.97 9.7 9.6 3.6 7.8 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF313) Mago_nashi PF02792.14 CBY32970.1 - 4.8 7.3 12.2 0.086 13.0 2.1 2.8 3 0 0 3 3 3 0 Mago nashi protein ApoO PF09769.9 CBY32970.1 - 6 6.9 7.5 8.8 6.3 1.6 3.0 3 0 0 3 3 3 0 Apolipoprotein O Y_phosphatase PF00102.27 CBY32971.1 - 8.5e-20 71.3 0.0 9.5e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase PF00102.27 CBY32972.1 - 3.8e-15 56.1 0.0 5.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 CBY32973.1 - 1.8e-72 243.9 0.0 2.9e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY32973.1 - 5.1e-42 144.0 0.0 8.9e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CBY32973.1 - 2.1e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 CBY32973.1 - 2.4e-08 33.6 0.1 4.4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY32973.1 - 2.1e-07 30.5 0.0 1.1e-06 28.2 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CBY32973.1 - 9e-06 24.9 0.7 1.3e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY32973.1 - 7.8e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY32973.1 - 0.00044 19.9 0.1 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase G8 PF10162.9 CBY32974.1 - 1e-38 132.2 0.7 3.8e-29 101.3 0.1 2.9 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY32974.1 - 2.7e-17 62.6 23.4 0.00024 21.1 0.5 8.2 7 1 0 7 7 7 5 IPT/TIG domain Beta_helix PF13229.6 CBY32974.1 - 4.1e-09 36.5 34.4 3.8e-05 23.6 0.9 6.1 7 0 0 7 7 7 3 Right handed beta helix region LRR_9 PF14580.6 CBY32974.1 - 0.0017 17.9 3.0 0.0046 16.5 3.0 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY32974.1 - 0.04 13.7 5.2 0.16 11.7 5.2 2.1 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 CBY32974.1 - 0.089 13.2 11.3 0.044 14.2 2.4 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Ribo_biogen_C PF04034.13 CBY32975.1 - 1.8e-49 166.7 0.0 2.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBY32975.1 - 6.2e-12 45.1 1.0 1.1e-11 44.3 1.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Myb_DNA-bind_4 PF13837.6 CBY32976.1 - 1.1e-06 28.9 6.1 0.0058 17.0 0.7 2.6 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CBY32976.1 - 0.28 11.5 4.8 0.27 11.6 1.3 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TnpV PF14198.6 CBY32976.1 - 3.2 7.8 8.2 0.49 10.4 1.3 2.8 3 0 0 3 3 3 0 Transposon-encoded protein TnpV PIP5K PF01504.18 CBY32977.1 - 3.9e-84 282.1 0.2 5.4e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Trypsin PF00089.26 CBY32978.1 - 4.5e-30 105.1 0.0 7.2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sulfotransfer_2 PF03567.14 CBY32979.1 - 6.6e-29 101.6 3.4 9.8e-29 101.0 3.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF4483 PF14825.6 CBY32980.1 - 2.8e-39 134.4 0.1 4.1e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) MukF_C PF17193.4 CBY32980.1 - 0.0078 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 MukF C-terminal domain Tropomodulin PF03250.14 CBY32981.1 - 0.0016 18.5 1.1 0.0016 18.5 1.1 3.6 3 1 0 3 3 3 1 Tropomodulin RIG-I_C PF18119.1 CBY32981.1 - 0.17 11.9 3.5 0.29 11.1 1.4 2.3 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain RED_C PF07807.11 CBY32981.1 - 0.7 10.4 4.9 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 RED-like protein C-terminal region RAC_head PF16717.5 CBY32981.1 - 5.3 8.1 7.7 29 5.7 0.5 4.1 4 0 0 4 4 4 0 Ribosome-associated complex head domain UL42 PF17638.2 CBY32981.1 - 6 6.9 7.5 0.15 12.1 1.0 1.6 2 0 0 2 2 2 0 HCMV UL42 Phospholip_A2_1 PF00068.19 CBY32982.1 - 1.3e-05 25.6 0.0 1.3e-05 25.6 0.0 3.0 4 0 0 4 4 4 1 Phospholipase A2 Mucin PF01456.17 CBY32982.1 - 0.049 13.6 87.4 0.99 9.4 55.1 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein SOG2 PF10428.9 CBY32982.1 - 1.8 7.7 14.0 0.7 9.0 7.3 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein FSA_C PF10479.9 CBY32982.1 - 6.7 4.7 35.0 4.6 5.2 22.6 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Galactosyl_T PF01762.21 CBY32984.1 - 3.6e-17 62.8 0.1 1.2e-16 61.2 0.1 1.7 1 1 0 1 1 1 1 Galactosyltransferase Gal-3-0_sulfotr PF06990.11 CBY32985.1 - 2e-26 92.8 1.8 2.1e-26 92.8 1.8 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Alpha_kinase PF02816.18 CBY32986.1 - 9.5e-53 179.1 3.3 9.5e-53 179.1 3.3 1.6 2 0 0 2 2 2 1 Alpha-kinase family Sel1 PF08238.12 CBY32986.1 - 0.0018 18.9 1.0 2.4 9.0 0.1 3.0 3 0 0 3 3 3 2 Sel1 repeat DUF5447 PF17525.2 CBY32986.1 - 0.015 15.7 0.1 0.17 12.3 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5447) rve_3 PF13683.6 CBY32986.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain ATP-synt_S1 PF05827.12 CBY32986.1 - 0.12 12.2 1.4 0.24 11.3 1.4 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MAPEG PF01124.18 CBY32987.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 MAPEG family O-FucT PF10250.9 CBY32989.1 - 8.4e-11 42.1 0.0 4.6e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_79n PF03662.14 CBY32990.1 - 1.1e-42 146.1 0.5 5.5e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain ShlB PF03865.13 CBY32990.1 - 0.027 13.9 2.1 0.83 9.0 0.0 2.7 3 0 0 3 3 3 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB HTH_56 PF18662.1 CBY32990.1 - 0.11 12.5 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Cch helix turn helix domain Ammonium_transp PF00909.21 CBY32991.1 - 4.4e-80 269.3 16.4 5.8e-68 229.4 8.6 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family DUF4153 PF13687.6 CBY32991.1 - 0.0014 18.3 1.8 0.0014 18.3 1.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4153) Toxin_TOLIP PF00087.21 CBY32992.1 - 0.04 14.2 0.6 0.04 14.2 0.6 7.5 9 1 1 10 10 10 0 Snake toxin and toxin-like protein CLASP_N PF12348.8 CBY32993.1 - 1.2e-18 67.6 15.4 8.5e-07 28.8 0.3 4.1 4 0 0 4 4 4 3 CLASP N terminal Cnd1 PF12717.7 CBY32993.1 - 3e-06 27.4 12.8 0.013 15.6 0.2 5.4 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBY32993.1 - 1.6e-05 25.4 2.4 0.014 16.0 0.1 4.5 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CBY32993.1 - 2e-05 24.7 0.2 0.028 14.6 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CBY32993.1 - 6.7e-05 23.2 0.5 5.7 7.4 0.0 5.2 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 CBY32993.1 - 0.00051 20.1 2.1 94 3.7 0.0 7.1 8 0 0 8 8 8 0 HEAT repeat Cnd3 PF12719.7 CBY32993.1 - 0.024 13.8 2.6 0.027 13.7 0.4 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CNOT11 PF10155.9 CBY32993.1 - 0.04 14.1 2.4 4.6 7.4 0.6 4.1 3 1 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 Sigma_1s PF02454.16 CBY32993.1 - 0.049 13.6 0.2 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Sigma 1s protein FAD-SLDH PF12318.8 CBY32993.1 - 0.11 12.5 0.4 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Proteasome PF00227.26 CBY32995.1 - 1.1e-58 197.9 0.0 1.4e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY32995.1 - 1.5e-09 37.4 0.0 2.5e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Myb_Cef PF11831.8 CBY32996.1 - 1e-63 215.1 0.2 1e-63 215.1 0.2 3.9 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CBY32996.1 - 1.9e-19 69.6 6.2 1.3e-10 41.3 1.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY32996.1 - 3.3e-19 68.9 3.8 3.9e-13 49.4 3.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CBY32996.1 - 1.1 9.4 4.2 2.4 8.3 0.2 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WD40 PF00400.32 CBY32997.1 - 3.5e-14 53.0 5.0 0.00024 21.9 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY32997.1 - 1.3e-13 51.1 0.1 6.7e-07 29.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY32997.1 - 0.0046 16.9 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY32997.1 - 0.0059 15.6 0.1 0.76 8.7 0.1 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBY32997.1 - 0.055 13.4 0.1 20 5.2 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Aminotran_3 PF00202.21 CBY32998.1 - 3.6e-97 325.6 0.0 4.4e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MRP-S32 PF10210.9 CBY32998.1 - 0.1 13.1 0.2 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Tctex-1 PF03645.13 CBY32999.1 - 9.4e-21 74.0 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Cpn60_TCP1 PF00118.24 CBY33000.1 - 4.6e-137 457.6 7.3 5.3e-137 457.4 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 CBY33000.1 - 0.046 13.3 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 Propionate catabolism activator RRM_1 PF00076.22 CBY33001.1 - 1.9e-22 78.8 0.0 2.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY33001.1 - 0.00041 20.0 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY33001.1 - 0.0055 16.8 0.0 0.0083 16.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif BRAP2 PF07576.12 CBY33001.1 - 0.012 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 BRCA1-associated protein 2 HDNR PF15115.6 CBY33003.1 - 0.009 16.3 3.6 0.061 13.6 3.6 2.1 1 1 0 1 1 1 1 Domain of unknown function with conserved HDNR motif PKD_channel PF08016.12 CBY33004.1 - 3.9e-26 91.7 8.3 3.9e-26 91.7 8.3 2.1 2 0 0 2 2 2 1 Polycystin cation channel CitMHS PF03600.16 CBY33004.1 - 0.0052 16.0 7.5 0.05 12.8 0.5 2.4 2 0 0 2 2 2 2 Citrate transporter Ephrin_rec_like PF07699.13 CBY33005.1 - 4.5e-18 64.7 169.6 1.9e-05 24.3 12.7 16.6 5 2 13 18 18 18 14 Putative ephrin-receptor like EGF_CA PF07645.15 CBY33005.1 - 3.6e-07 30.3 9.0 3.6e-07 30.3 9.0 13.9 11 4 3 14 14 14 1 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY33005.1 - 0.00072 19.8 8.7 0.00072 19.8 8.7 13.5 11 5 0 11 11 11 2 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY33005.1 - 0.0012 18.7 1.2 0.0012 18.7 1.2 13.9 14 2 0 14 14 14 2 Complement Clr-like EGF-like Ank_2 PF12796.7 CBY33006.1 - 5.5e-56 187.1 31.4 2.8e-10 40.6 0.1 10.7 4 3 7 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY33006.1 - 2.2e-52 174.8 19.8 1.6e-06 28.5 0.1 15.0 9 5 7 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY33006.1 - 1.7e-38 130.1 17.1 2.1e-06 27.9 0.4 13.5 9 3 5 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33006.1 - 8.5e-38 124.1 16.3 0.022 15.3 0.0 19.2 22 0 0 22 22 22 9 Ankyrin repeat Ank PF00023.30 CBY33006.1 - 2.6e-29 100.4 21.0 0.011 16.2 0.0 16.3 17 1 0 17 17 17 5 Ankyrin repeat FYVE PF01363.21 CBY33006.1 - 1.3e-13 50.8 6.9 1.3e-13 50.8 6.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger BTB PF00651.31 CBY33006.1 - 1.1e-09 38.5 0.7 2.4e-09 37.4 0.2 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF2482 PF10655.9 CBY33006.1 - 1.1 9.8 4.8 1 9.9 1.5 2.7 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) PAS_9 PF13426.7 CBY33007.1 - 4.7e-07 30.0 0.0 5.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY33007.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 PAS fold Ion_trans PF00520.31 CBY33008.1 - 7.1e-24 84.4 16.9 9.7e-24 83.9 16.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY33008.1 - 4.7e-11 42.5 3.4 4.7e-11 42.5 3.4 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY33008.1 - 1.4e-05 25.1 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SVIP PF15811.5 CBY33009.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Small VCP/p97-interacting protein EGF PF00008.27 CBY33010.1 - 2.5e-07 30.8 8.8 7.4e-07 29.4 6.6 2.0 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CBY33010.1 - 3.2e-05 24.4 3.7 3.2e-05 24.4 3.7 2.7 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_CA PF07645.15 CBY33010.1 - 0.0018 18.4 4.1 0.0018 18.4 4.1 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY33010.1 - 0.0035 17.5 9.8 0.018 15.2 7.1 2.3 1 1 1 2 2 2 1 EGF domain MDH PF02315.16 CBY33010.1 - 0.3 11.2 3.1 6.8 6.8 0.1 2.0 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit EGF_2 PF07974.13 CBY33010.1 - 0.49 10.8 10.4 1 9.8 5.5 2.2 2 0 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 CBY33010.1 - 0.98 9.8 10.4 0.26 11.6 5.8 2.1 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Ig_3 PF13927.6 CBY33011.1 - 2e-23 82.8 0.2 3.8e-10 40.2 0.0 3.8 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CBY33011.1 - 3.3e-17 62.3 1.3 3.2e-08 33.5 0.0 3.8 3 1 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY33011.1 - 4.8e-17 62.1 1.0 2.9e-08 33.9 0.0 4.1 3 2 2 5 5 5 3 Immunoglobulin domain ig PF00047.25 CBY33011.1 - 7.8e-12 45.2 2.1 0.00022 21.3 0.0 4.1 4 1 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 CBY33011.1 - 5.6e-10 39.5 2.4 0.00013 22.3 0.1 3.6 3 0 0 3 3 3 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain V-set PF07686.17 CBY33011.1 - 1.6e-09 37.9 1.1 0.0032 17.6 0.1 4.5 3 2 1 4 4 4 2 Immunoglobulin V-set domain Ig_4 PF16680.5 CBY33011.1 - 1.2e-08 35.1 1.2 0.00055 20.2 0.0 3.1 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 CBY33011.1 - 0.0015 18.0 0.0 0.034 13.7 0.0 2.8 3 0 0 3 3 3 1 Immunoglobulin domain Protocadherin PF08374.11 CBY33011.1 - 0.012 15.6 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Protocadherin C2-set PF05790.15 CBY33011.1 - 0.023 14.9 0.2 10 6.4 0.0 3.6 2 1 2 4 4 4 0 Immunoglobulin C2-set domain EphA2_TM PF14575.6 CBY33011.1 - 0.031 15.1 0.0 0.073 14.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Izumo-Ig PF16706.5 CBY33011.1 - 0.098 12.7 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain Lectin_C PF00059.21 CBY33012.1 - 3.9e-11 43.6 0.1 2.1e-10 41.3 0.0 2.2 3 0 0 3 3 3 1 Lectin C-type domain NPV_P10 PF05531.12 CBY33012.1 - 0.013 15.9 5.3 1.9 9.0 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ifi-6-16 PF06140.13 CBY33013.1 - 6.3e-07 29.2 10.5 2.2e-06 27.5 10.4 1.9 1 1 0 1 1 1 1 Interferon-induced 6-16 family TMEM40 PF15817.5 CBY33013.1 - 0.13 12.1 1.3 0.19 11.5 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 40 family DUF2207 PF09972.9 CBY33013.1 - 0.19 10.5 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ECF_trnsprt PF12822.7 CBY33013.1 - 0.34 11.0 8.7 0.43 10.6 8.7 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Metallophos PF00149.28 CBY33016.1 - 3.6e-07 30.9 0.1 5.3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 CBY33016.1 - 0.0038 16.3 0.0 0.29 10.1 0.1 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Cornifin PF02389.15 CBY33017.1 - 0.64 10.2 47.4 7.1 6.8 47.4 2.0 1 1 0 1 1 1 0 Cornifin (SPRR) family Arf PF00025.21 CBY33018.1 - 1.1e-58 197.6 0.0 1.4e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY33018.1 - 1.7e-15 57.0 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33018.1 - 3.2e-15 56.4 0.0 4.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBY33018.1 - 2.1e-14 53.5 1.2 4.4e-08 32.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY33018.1 - 1.6e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY33018.1 - 4e-10 39.4 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 6PF2K PF01591.18 CBY33018.1 - 9e-05 21.9 0.2 0.00015 21.1 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 CBY33018.1 - 0.0039 17.3 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 CBY33018.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase Clat_adaptor_s PF01217.20 CBY33019.1 - 1.4e-53 180.7 2.4 1.7e-53 180.4 2.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3919 PF13057.6 CBY33019.1 - 0.043 13.4 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Clat_adaptor_s PF01217.20 CBY33020.1 - 1.5e-40 138.4 1.3 1.9e-40 138.1 1.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SBDS PF01172.18 CBY33020.1 - 0.15 12.2 0.2 0.48 10.5 0.0 1.9 2 1 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Metallophos PF00149.28 CBY33022.1 - 8e-31 108.1 0.2 1.1e-30 107.7 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CBY33022.1 - 3.1e-21 75.5 0.6 5.3e-21 74.7 0.6 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region N_Asn_amidohyd PF14736.6 CBY33023.1 - 1.8e-98 329.0 0.0 2.2e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase PNP_UDP_1 PF01048.20 CBY33024.1 - 2.9e-36 124.9 0.0 3.3e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.6 CBY33025.1 - 9.6e-06 26.4 0.0 2.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 CBY33025.1 - 1.7e-05 24.6 13.1 0.0082 16.2 1.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY33025.1 - 0.0053 16.9 0.0 5 7.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY33025.1 - 0.0059 16.4 6.8 7.7 6.5 0.6 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY33025.1 - 0.011 15.1 1.5 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 SHNi-TPR Fis1_TPR_C PF14853.6 CBY33025.1 - 0.054 13.6 2.0 0.43 10.7 0.0 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CBY33025.1 - 0.059 14.0 1.5 9 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBY33025.1 - 0.1 13.5 0.7 44 5.3 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY33025.1 - 1.1 10.0 3.4 2e+02 3.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 CBY33025.1 - 1.7 8.7 5.9 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_12 PF13424.6 CBY33025.1 - 4.1 7.8 8.1 9.3 6.6 0.2 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ASC PF00858.24 CBY33028.1 - 1e-54 186.2 13.4 1.2e-54 185.9 13.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.16 CBY33029.1 - 2e-24 86.4 19.0 2.5e-24 86.1 19.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY33029.1 - 3.4e-10 40.2 7.0 3.4e-10 40.2 7.0 2.2 2 0 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.19 CBY33029.1 - 0.17 12.6 0.2 0.17 12.6 0.2 3.1 2 1 1 3 3 3 0 Small Multidrug Resistance protein Claudin_2 PF13903.6 CBY33031.1 - 0.00055 19.7 10.3 0.0016 18.3 10.3 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY33031.1 - 0.017 15.0 5.0 0.049 13.5 5.0 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family zf-C4 PF00105.18 CBY33032.1 - 4.3e-07 30.3 14.0 9e-07 29.3 14.0 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DUF4116 PF13475.6 CBY33032.1 - 0.065 13.0 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Zn_protease PF05618.11 CBY33032.1 - 0.076 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease PLAT PF01477.23 CBY33033.1 - 1.4e-11 45.0 3.3 0.00026 21.5 0.0 5.2 4 1 0 4 4 4 3 PLAT/LH2 domain Ig_3 PF13927.6 CBY33034.1 - 4.8e-21 75.1 2.0 5.6e-07 30.1 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain I-set PF07679.16 CBY33034.1 - 2.5e-14 53.1 1.4 0.00068 19.7 0.0 3.5 3 0 0 3 3 3 3 Immunoglobulin I-set domain ig PF00047.25 CBY33034.1 - 2.6e-14 53.2 2.7 0.00028 21.0 0.2 3.4 3 1 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY33034.1 - 2.6e-12 46.7 1.1 9.5e-10 38.4 0.0 3.0 3 1 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Ig_2 PF13895.6 CBY33034.1 - 2.9e-12 46.8 3.6 0.016 15.5 0.2 3.6 1 1 2 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY33034.1 - 3.8e-08 33.5 1.8 2.4e-06 27.7 0.2 3.2 3 0 0 3 3 3 1 Immunoglobulin V-set domain Adeno_E3_CR1 PF02440.15 CBY33034.1 - 0.013 15.2 0.7 0.045 13.5 0.0 2.2 2 1 1 3 3 3 0 Adenovirus E3 region protein CR1 Protocadherin PF08374.11 CBY33034.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 CBY33034.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family CRPA PF05745.11 CBY33034.1 - 0.043 13.8 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tropomyosin PF00261.20 CBY33035.1 - 1e-49 169.1 61.7 7.6e-45 153.1 46.6 2.0 1 1 1 2 2 2 2 Tropomyosin Tropomyosin_1 PF12718.7 CBY33035.1 - 6.2e-15 55.6 57.5 6.5e-14 52.3 31.8 2.9 1 1 1 2 2 2 2 Tropomyosin like Laminin_II PF06009.12 CBY33035.1 - 3.1e-08 33.7 29.8 0.0033 17.4 9.3 3.2 1 1 2 3 3 3 3 Laminin Domain II DUF4315 PF14193.6 CBY33035.1 - 0.011 15.7 3.2 0.011 15.7 3.2 5.2 3 3 1 4 4 4 0 Domain of unknown function (DUF4315) DUF1664 PF07889.12 CBY33035.1 - 0.027 14.5 30.8 0.06 13.4 1.9 4.4 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 CBY33035.1 - 0.12 12.6 16.3 1.6 9.0 1.3 4.6 3 2 0 3 3 3 0 Proteins of 100 residues with WXG DAPDH_C PF16654.5 CBY33035.1 - 0.19 11.6 6.1 0.058 13.3 1.1 2.2 2 0 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain ERM PF00769.19 CBY33035.1 - 0.68 9.7 60.7 5.8 6.7 43.0 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PspA_IM30 PF04012.12 CBY33035.1 - 1.4 8.5 47.4 0.014 14.9 16.0 3.2 1 1 2 3 3 2 0 PspA/IM30 family Synaptobrevin PF00957.21 CBY33035.1 - 2.9 7.7 27.8 0.83 9.5 2.6 4.7 2 2 2 4 4 4 0 Synaptobrevin DUF3450 PF11932.8 CBY33035.1 - 3.9 6.7 39.1 0.1 11.9 4.2 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBY33035.1 - 4 6.2 51.4 0.51 9.2 11.8 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein FPP PF05911.11 CBY33035.1 - 7.7 4.6 47.4 12 3.9 29.7 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Ribosomal_L4 PF00573.22 CBY33037.1 - 1.9e-25 89.7 0.6 2.3e-25 89.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PDZ PF00595.24 CBY33039.1 - 3.7e-11 43.2 0.1 6.6e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY33039.1 - 1.2e-06 28.2 0.1 2.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY33039.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF433 PF04255.14 CBY33041.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Herpes_UL73 PF03554.13 CBY33041.1 - 0.068 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein VEG PF06257.11 CBY33041.1 - 0.26 11.3 1.1 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Biofilm formation stimulator VEG Gal-3-0_sulfotr PF06990.11 CBY33042.1 - 3.8e-62 210.5 6.2 2e-60 204.8 6.2 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY33042.1 - 0.00059 19.8 0.2 0.0026 17.7 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase family Csa1 PF06023.12 CBY33043.1 - 0.1 11.9 0.5 0.18 11.2 0.2 1.5 2 0 0 2 2 2 0 CRISPR-associated exonuclease Csa1 EF-hand_1 PF00036.32 CBY33044.1 - 4.3e-17 60.3 13.1 0.0002 20.7 0.0 6.5 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 CBY33044.1 - 1.3e-16 59.1 11.8 0.0031 17.3 0.0 6.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 CBY33044.1 - 1e-14 54.7 20.5 8.7e-07 29.3 0.4 5.0 2 2 5 7 7 7 6 EF-hand domain pair EF-hand_5 PF13202.6 CBY33044.1 - 8.7e-13 47.1 19.6 0.0001 21.6 0.3 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.9 CBY33044.1 - 8.2e-05 22.9 15.8 0.14 12.5 1.0 3.9 1 1 3 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY33044.1 - 0.0012 18.6 1.7 0.56 10.1 0.1 4.2 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY33044.1 - 0.011 15.5 16.1 1.4 8.9 0.0 5.4 6 1 0 6 6 6 0 EF-hand domain pair DUF1707 PF08044.11 CBY33044.1 - 0.071 13.2 0.3 9.1 6.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_4 PF12763.7 CBY33044.1 - 7.2 6.6 14.4 3.7 7.6 2.7 3.9 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand zf-C2H2 PF00096.26 CBY33046.1 - 4.3e-15 55.2 19.7 6.4e-05 23.2 2.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY33046.1 - 2.5e-10 40.3 10.2 5.5e-07 29.7 1.9 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY33046.1 - 1.6e-08 34.7 18.6 0.0013 19.4 2.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY33046.1 - 0.00047 20.7 8.4 0.036 14.7 0.8 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain Ogr_Delta PF04606.12 CBY33046.1 - 0.0054 16.7 1.2 0.072 13.1 0.3 2.6 1 1 1 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 CBY33046.1 - 0.079 13.3 3.9 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY33046.1 - 0.083 12.9 1.1 0.083 12.9 1.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY33046.1 - 1.9 8.2 9.6 0.34 10.6 0.9 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY33046.1 - 2.2 8.8 6.2 0.99 9.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Calsarcin PF05556.11 CBY33047.1 - 0.0046 16.5 0.1 0.0097 15.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-binding protein (Calsarcin) TRAM_LAG1_CLN8 PF03798.16 CBY33048.1 - 5.5e-15 55.6 17.8 6.2e-15 55.5 17.8 1.0 1 0 0 1 1 1 1 TLC domain Motile_Sperm PF00635.26 CBY33049.1 - 6.3e-14 51.8 0.8 1.7e-13 50.4 0.7 1.9 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Frizzled PF01534.17 CBY33050.1 - 3.4e-50 170.9 16.2 4.7e-50 170.5 16.2 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY33050.1 - 4.8e-20 72.2 0.3 1.1e-19 71.1 0.3 1.6 1 0 0 1 1 1 1 Fz domain GON PF08685.11 CBY33051.1 - 3.6e-63 213.1 0.1 3.6e-63 213.1 0.1 2.6 2 0 0 2 2 2 1 GON domain TSP_1 PF00090.19 CBY33051.1 - 1.9e-44 149.6 286.1 8.4e-09 35.5 11.3 20.8 21 1 0 21 21 21 16 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 CBY33051.1 - 2.2e-13 50.5 9.0 2.2e-13 50.5 9.0 11.2 9 4 1 10 10 10 2 ADAM cysteine-rich domain Reprolysin PF01421.19 CBY33051.1 - 1.1e-10 41.8 0.8 1.1e-10 41.8 0.8 2.2 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_5 PF13688.6 CBY33051.1 - 5.2e-06 26.7 0.1 2.5e-05 24.5 0.1 2.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY33051.1 - 5.3e-06 27.0 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY33051.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY33051.1 - 0.003 17.5 0.1 0.0081 16.1 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DBD_Tnp_Hermes PF10683.9 CBY33051.1 - 0.071 12.8 4.5 13 5.5 0.1 3.8 3 0 0 3 3 3 0 Hermes transposase DNA-binding domain FOLN PF09289.10 CBY33051.1 - 0.38 11.0 6.6 2.9 8.2 0.2 4.6 3 0 0 3 3 3 0 Follistatin/Osteonectin-like EGF domain Ribosomal_L2_C PF03947.18 CBY33052.1 - 3.2e-43 146.9 3.5 5.1e-43 146.3 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBY33052.1 - 1.9e-15 56.6 0.2 5e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L22 PF00237.19 CBY33053.1 - 2.7e-40 136.8 0.1 4.6e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CRAL_TRIO PF00650.20 CBY33054.1 - 1.2e-23 83.6 0.2 1.7e-23 83.1 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBY33054.1 - 8.5e-06 25.9 8.3 1.1e-05 25.5 1.5 2.7 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CBY33054.1 - 0.019 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain FlgM PF04316.13 CBY33054.1 - 0.059 13.7 0.4 0.11 12.9 0.4 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF1947 PF09183.10 CBY33054.1 - 0.12 12.6 4.8 4.6 7.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Phospholip_A2_1 PF00068.19 CBY33057.1 - 1.6e-14 54.3 3.2 1.6e-14 54.3 3.2 1.6 2 0 0 2 2 2 1 Phospholipase A2 DUF346 PF03984.13 CBY33057.1 - 0.13 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) OAF PF14941.6 CBY33058.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Transcriptional regulator, Out at first RVT_1 PF00078.27 CBY33059.1 - 1.5e-12 47.5 0.0 1.8e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) OFeT_1 PF16955.5 CBY33059.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter ACT_7 PF13840.6 CBY33062.1 - 3.2e-11 42.9 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_3 PF10000.9 CBY33062.1 - 3.7e-08 33.2 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ACT domain Collagen PF01391.18 CBY33063.1 - 4.2e-17 61.6 85.0 8.6e-07 28.6 36.2 3.4 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) Spc7 PF08317.11 CBY33064.1 - 0.015 14.2 13.0 0.02 13.8 13.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM184 PF15665.5 CBY33064.1 - 0.02 14.7 10.3 0.65 9.7 0.5 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PRKG1_interact PF15898.5 CBY33064.1 - 0.021 15.7 13.0 0.47 11.4 8.5 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 CBY33064.1 - 0.022 15.2 5.0 0.33 11.4 2.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 CBY33064.1 - 0.024 14.9 9.3 0.093 13.0 1.4 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper Tup_N PF08581.10 CBY33064.1 - 0.028 14.7 12.4 1.1 9.6 5.9 2.8 1 1 2 3 3 3 0 Tup N-terminal BST2 PF16716.5 CBY33064.1 - 0.039 14.5 6.0 0.039 14.5 6.0 2.7 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 GreA_GreB_N PF03449.15 CBY33064.1 - 0.04 14.1 4.1 0.04 14.1 4.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DUF3584 PF12128.8 CBY33064.1 - 0.053 11.1 11.5 0.067 10.7 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 CBY33064.1 - 0.072 13.1 17.5 0.73 9.9 13.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.6 CBY33064.1 - 0.073 13.3 6.0 0.037 14.2 4.0 1.6 2 0 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SLATT_6 PF18169.1 CBY33064.1 - 0.073 12.7 7.6 2 8.0 3.3 2.3 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 DUF883 PF05957.13 CBY33064.1 - 0.11 13.2 1.7 0.3 11.7 0.7 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.14 CBY33064.1 - 0.11 12.3 10.7 0.16 11.8 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Pox_A_type_inc PF04508.12 CBY33064.1 - 0.12 12.3 0.4 0.12 12.3 0.4 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 CBY33064.1 - 0.13 12.4 7.9 0.2 11.7 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBY33064.1 - 0.13 12.0 13.1 3.3 7.6 0.0 3.1 2 1 0 2 2 2 0 Septum formation initiator APC_N_CC PF16689.5 CBY33064.1 - 0.18 11.9 6.3 0.53 10.4 2.6 2.7 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF4515 PF14988.6 CBY33064.1 - 0.18 11.6 16.1 0.57 10.0 16.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2524 PF10732.9 CBY33064.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) LMBR1 PF04791.16 CBY33064.1 - 0.22 10.4 4.1 0.26 10.1 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 CBY33064.1 - 0.25 11.4 8.5 5.3 7.1 0.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 CBY33064.1 - 0.31 11.4 10.3 1.2 9.5 10.3 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 CBY33064.1 - 0.38 10.8 13.5 3.8 7.6 9.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CBY33064.1 - 0.52 10.5 12.8 0.6 10.3 8.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HIP1_clath_bdg PF16515.5 CBY33064.1 - 0.76 10.4 12.6 1.5 9.4 7.6 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 CBY33064.1 - 0.83 10.1 18.0 1.8 9.1 0.3 2.8 1 1 1 2 2 2 0 Cell division protein ZapB Rho_Binding PF08912.11 CBY33064.1 - 0.85 10.5 13.6 0.83 10.5 9.2 2.7 1 1 2 3 3 3 0 Rho Binding DUF2681 PF10883.8 CBY33064.1 - 0.86 10.0 11.4 0.82 10.1 8.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) FlxA PF14282.6 CBY33064.1 - 1 9.4 17.7 0.93 9.5 13.7 2.4 1 1 1 2 2 2 0 FlxA-like protein Csm1_N PF18504.1 CBY33064.1 - 1.3 9.5 12.2 0.88 10.0 6.2 2.9 3 1 1 4 4 3 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 CBY33064.1 - 1.6 9.1 12.7 17 5.7 6.7 3.5 2 2 0 2 2 2 0 ABC transporter C-terminal domain MCC-bdg_PDZ PF10506.9 CBY33064.1 - 2.3 8.3 6.7 18 5.5 0.8 2.9 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome APG6_N PF17675.1 CBY33064.1 - 3.6 8.1 14.2 39 4.8 14.2 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 CBY33064.1 - 3.6 6.1 16.0 5.5 5.5 16.0 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 CBY33064.1 - 4.8 7.9 11.0 17 6.2 5.2 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Acyl-CoA_dh_1 PF00441.24 CBY33065.1 - 2.9e-30 105.4 0.6 4e-30 105.0 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY33065.1 - 2e-17 63.8 0.1 6.2e-17 62.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY33065.1 - 3.4e-09 37.1 0.6 4.9e-09 36.6 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY33065.1 - 3.9e-08 33.4 0.0 8.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain NLBH PF05211.12 CBY33066.1 - 0.21 11.1 6.2 1.3 8.6 0.4 2.2 1 1 1 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) PTR2 PF00854.21 CBY33067.1 - 2.1e-13 49.9 0.1 6.5e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 POT family DUF3425 PF11905.8 CBY33067.1 - 0.034 14.1 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) PLAC8 PF04749.17 CBY33069.1 - 6.2e-08 33.6 2.8 7.1e-08 33.4 2.8 1.2 1 0 0 1 1 1 1 PLAC8 family Cadherin PF00028.17 CBY33070.1 - 4.8e-54 180.8 0.1 1.6e-13 50.9 0.0 6.1 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CBY33070.1 - 1.5e-07 31.2 0.3 0.18 11.6 0.0 4.3 5 0 0 5 5 5 2 Cadherin-like Cadherin_3 PF16184.5 CBY33070.1 - 1.1e-05 25.3 4.3 0.27 11.2 0.1 4.7 5 0 0 5 5 5 3 Cadherin-like RET_CLD1 PF17756.1 CBY33070.1 - 0.0013 19.0 0.0 1.7 8.9 0.0 2.8 3 0 0 3 3 3 2 RET Cadherin like domain 1 Thiolase_N PF00108.23 CBY33071.1 - 6.4e-21 74.9 0.2 1.3e-19 70.6 0.2 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY33071.1 - 1.7e-12 47.1 0.3 6.7e-12 45.1 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY33071.1 - 0.0001 22.0 1.5 0.00063 19.4 1.5 2.1 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBY33071.1 - 0.001 18.8 0.3 0.16 11.8 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 CBY33071.1 - 0.0012 18.8 0.2 0.16 12.0 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain NMT1 PF09084.11 CBY33071.1 - 0.085 12.8 0.1 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 NMT1/THI5 like Ion_trans PF00520.31 CBY33072.1 - 2.6e-42 144.8 46.0 4.8e-23 81.7 13.6 2.1 2 0 0 2 2 2 2 Ion transport protein BLIP PF07467.11 CBY33073.1 - 0.051 14.2 0.1 0.063 13.9 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) RNA_pol_3_Rpc31 PF11705.8 CBY33074.1 - 7.5e-11 42.7 11.7 1e-10 42.3 11.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 YnfE PF17452.2 CBY33074.1 - 0.25 11.7 4.9 1.9 8.9 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized YnfE-like LRR19-TM PF15176.6 CBY33074.1 - 1.2 9.1 4.3 2.5 8.1 2.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DHHC PF01529.20 CBY33075.1 - 2e-31 108.8 11.6 2e-31 108.8 11.6 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Cytochrome-c551 PF10643.9 CBY33075.1 - 0.0016 18.1 0.7 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 Photosystem P840 reaction-centre cytochrome c-551 DUF2207 PF09972.9 CBY33075.1 - 0.0027 16.5 5.7 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Tmemb_9 PF05434.11 CBY33075.1 - 0.051 13.5 0.3 0.051 13.5 0.3 2.7 2 1 1 3 3 3 0 TMEM9 MAP17 PF15807.5 CBY33075.1 - 2.2 8.5 4.7 0.39 11.0 0.2 2.1 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CHGN PF05679.16 CBY33076.1 - 3.4e-62 211.0 5.7 5.4e-38 131.1 0.0 2.2 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY33076.1 - 6.8e-11 42.1 0.1 1.4e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY33076.1 - 6.8e-07 28.9 0.2 1.6e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY33076.1 - 6.5e-05 22.8 1.1 0.015 15.1 0.1 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 CBY33076.1 - 0.016 15.1 0.2 0.093 12.5 0.0 2.2 2 0 0 2 2 2 0 Galactosyltransferase rve PF00665.26 CBY33077.1 - 3.2e-13 49.9 0.0 1.2e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY33077.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain 7tm_1 PF00001.21 CBY33078.1 - 5.7e-15 55.4 14.8 1.6e-13 50.6 14.8 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY33078.1 - 0.031 13.4 9.4 0.089 11.9 9.3 1.9 1 1 0 1 1 1 0 Taste receptor protein (TAS2R) Voltage_CLC PF00654.20 CBY33078.1 - 0.43 9.8 5.8 1.1 8.4 5.9 1.7 1 1 0 1 1 1 0 Voltage gated chloride channel Yip1 PF04893.17 CBY33078.1 - 3.4 7.3 10.1 0.14 11.8 2.5 2.2 2 1 0 2 2 2 0 Yip1 domain MA3 PF02847.17 CBY33079.1 - 0.059 13.4 0.8 0.46 10.5 0.3 2.5 3 0 0 3 3 3 0 MA3 domain RHH_6 PF16762.5 CBY33079.1 - 0.98 10.1 4.7 1.8 9.3 0.2 3.2 2 2 1 4 4 4 0 Ribbon-helix-helix domain FAM25 PF15825.5 CBY33079.1 - 6.1 7.3 7.4 28 5.2 0.9 3.1 2 1 1 3 3 3 0 FAM25 family RepA_N PF06970.11 CBY33081.1 - 0.11 12.4 0.1 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Hid1 PF12722.7 CBY33081.1 - 6.4 4.8 11.9 9.9 4.1 11.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EGF_CA PF07645.15 CBY33082.1 - 2.8e-14 53.0 52.3 2.9e-08 33.8 4.3 5.5 3 1 2 5 5 5 3 Calcium-binding EGF domain cEGF PF12662.7 CBY33082.1 - 4.9e-13 48.7 19.4 2.3e-05 24.2 0.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY33082.1 - 2.2e-08 34.2 64.5 4.1e-07 30.2 4.6 5.4 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY33082.1 - 0.0058 16.9 2.5 0.0058 16.9 2.5 6.7 4 2 0 5 5 5 2 EGF-like domain EGF_3 PF12947.7 CBY33082.1 - 0.035 14.3 1.5 0.035 14.3 1.5 5.7 5 1 0 5 5 5 0 EGF domain RR_TM4-6 PF06459.12 CBY33083.1 - 0.062 13.1 6.5 0.081 12.7 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Calpain_III PF01067.22 CBY33083.1 - 0.33 11.2 3.3 0.18 12.1 0.6 1.8 2 1 0 2 2 2 0 Calpain large subunit, domain III ATP-synt_8 PF00895.20 CBY33084.1 - 0.0019 18.6 4.3 0.94 10.0 0.2 3.1 3 0 0 3 3 3 2 ATP synthase protein 8 DUF2207 PF09972.9 CBY33084.1 - 0.78 8.4 3.0 1.4 7.6 0.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3112 PF11309.8 CBY33084.1 - 2.4 7.6 7.1 0.3 10.5 0.4 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3112) HemY_N PF07219.13 CBY33084.1 - 3.1 8.0 7.3 4.4 7.5 0.0 3.0 3 0 0 3 3 3 0 HemY protein N-terminus DUF3094 PF11293.8 CBY33084.1 - 3.2 7.6 6.6 0.18 11.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) EphA2_TM PF14575.6 CBY33084.1 - 4.7 8.2 4.9 81 4.2 0.0 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ac81 PF05820.11 CBY33084.1 - 7.8 6.0 8.5 0.42 10.2 2.7 1.8 2 0 0 2 2 2 0 Baculoviridae AC81 DUF4231 PF14015.6 CBY33084.1 - 8.7 6.9 6.7 15 6.1 3.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Baculo_PEP_C PF04513.12 CBY33085.1 - 3 7.9 9.3 0.34 10.9 3.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1676 PF07898.13 CBY33086.1 - 0.96 9.5 6.6 0.81 9.7 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) zf-RING_2 PF13639.6 CBY33089.1 - 0.03 14.6 1.0 0.03 14.6 1.0 4.3 4 0 0 4 4 4 0 Ring finger domain Esterase PF00756.20 CBY33090.1 - 2.7e-51 174.7 0.0 3.1e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 CBY33090.1 - 5.5e-06 25.5 0.0 8.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CBY33090.1 - 0.001 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CBY33090.1 - 0.0011 18.0 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Peptidase_S9 PF00326.21 CBY33090.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 CBY33090.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF953 PF06110.11 CBY33091.1 - 2.2e-43 146.7 0.0 2.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 CBY33091.1 - 0.019 14.9 0.1 0.046 13.7 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 CBY33091.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CBY33091.1 - 0.18 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin Aldolase_II PF00596.21 CBY33092.1 - 5.1e-21 75.4 0.0 2.8e-20 73.0 0.0 1.9 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PLAC8 PF04749.17 CBY33093.1 - 2.8e-10 41.1 11.8 3.8e-10 40.7 11.8 1.2 1 0 0 1 1 1 1 PLAC8 family PMP22_Claudin PF00822.20 CBY33094.1 - 2e-11 44.0 4.3 2.6e-11 43.7 4.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY33094.1 - 0.00013 22.2 2.9 0.0003 21.0 2.9 1.5 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY33094.1 - 0.074 12.8 1.7 0.094 12.5 0.3 1.7 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 CBY33095.1 - 2e-11 44.0 4.3 2.6e-11 43.7 4.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY33095.1 - 0.00082 19.6 5.4 0.00092 19.5 4.7 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY33095.1 - 0.075 12.8 1.7 0.094 12.5 0.3 1.7 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1480 PF07351.13 CBY33096.1 - 0.008 16.4 2.0 0.022 15.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1480) Kelch_1 PF01344.25 CBY33097.1 - 1.7e-35 120.4 0.3 6.5e-11 41.6 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CBY33097.1 - 3.6e-26 90.5 0.1 2.1e-06 27.8 0.0 6.2 2 2 4 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CBY33097.1 - 3.7e-17 61.5 0.1 0.00038 20.3 0.2 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CBY33097.1 - 5e-16 58.3 0.4 0.016 15.2 0.0 6.6 8 0 0 8 8 8 4 Kelch motif Kelch_3 PF13415.6 CBY33097.1 - 7.9e-16 57.9 0.0 0.00021 21.5 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain BACK PF07707.15 CBY33097.1 - 8.7e-14 51.5 0.0 2.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 CBY33097.1 - 1.4e-11 44.6 0.0 2.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Kelch_4 PF13418.6 CBY33097.1 - 9.4e-11 41.5 2.7 0.00015 21.7 0.0 5.6 4 1 1 5 5 5 1 Galactose oxidase, central domain RIC3 PF15361.6 CBY33097.1 - 6.1 7.2 6.2 0.6 10.5 1.4 1.8 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CAP_N PF01213.19 CBY33098.1 - 0.039 13.4 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 CBY33099.1 - 4.2e-21 74.5 0.0 7.3e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY33099.1 - 0.00093 19.3 0.1 0.0021 18.2 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_8 PF11835.8 CBY33099.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain Nup35_RRM PF05172.13 CBY33099.1 - 0.058 13.4 0.0 0.32 11.0 0.0 2.1 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY33099.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb8 PF03870.15 CBY33100.1 - 1.8e-48 164.3 0.0 2e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CBY33100.1 - 1.3e-05 25.2 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G SCAB-Ig PF16709.5 CBY33100.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein LEM PF03020.15 CBY33101.1 - 1.1e-05 24.9 0.1 3.9e-05 23.1 0.1 2.1 1 0 0 1 1 1 1 LEM domain Ank_2 PF12796.7 CBY33101.1 - 0.00038 21.0 0.0 0.0016 19.0 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY33101.1 - 0.013 16.0 0.0 0.076 13.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 CBY33101.1 - 0.025 15.1 0.0 0.14 12.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat GST_C_3 PF14497.6 CBY33101.1 - 0.026 14.7 0.1 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.6 CBY33101.1 - 0.027 15.1 0.0 0.072 13.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PWI PF01480.17 CBY33102.1 - 9.7e-15 54.7 0.7 2.2e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 PWI domain DUF2884 PF11101.8 CBY33102.1 - 0.0058 16.2 4.3 0.009 15.5 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Activator-TraM PF11657.8 CBY33102.1 - 0.063 13.1 2.7 0.12 12.2 2.7 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Asp-B-Hydro_N PF05279.11 CBY33102.1 - 0.26 11.3 15.0 0.27 11.3 15.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3573 PF12097.8 CBY33102.1 - 0.29 9.9 2.1 0.36 9.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ketoacyl-synt PF00109.26 CBY33102.1 - 0.3 10.6 1.4 0.42 10.2 1.3 1.4 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain RSRP PF17069.5 CBY33102.1 - 2.1 7.8 46.3 2.8 7.4 46.3 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 ALMT PF11744.8 CBY33102.1 - 8.5 5.1 17.6 11 4.7 17.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter E3_UbLigase_R4 PF13764.6 CBY33103.1 - 5.2e-267 888.2 2.9 5.2e-267 888.2 2.9 2.9 5 0 0 5 5 5 1 E3 ubiquitin-protein ligase UBR4 YfbU PF03887.14 CBY33103.1 - 0.015 15.4 1.9 0.62 10.0 0.2 3.1 3 0 0 3 3 3 0 YfbU domain HTH_16 PF12645.7 CBY33103.1 - 0.071 13.2 0.1 1.6 8.8 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain BUD22 PF09073.10 CBY33103.1 - 0.34 10.2 13.2 1.5 8.1 13.2 2.1 1 0 0 1 1 1 0 BUD22 DUF3295 PF11702.8 CBY33103.1 - 2.6 7.3 8.5 8.3 5.6 8.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.12 CBY33103.1 - 5.1 5.2 19.2 15 3.6 19.2 1.7 1 0 0 1 1 1 0 Nop14-like family Homeodomain PF00046.29 CBY33104.1 - 2.1e-06 27.5 0.1 2.9e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY33104.1 - 0.00056 19.8 0.2 0.00086 19.2 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CBY33104.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 7tm_1 PF00001.21 CBY33106.1 - 3.6e-48 164.2 15.1 3.6e-48 164.2 15.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY33106.1 - 8.3e-11 41.8 11.7 9.6e-11 41.5 11.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srx PF10328.9 CBY33106.1 - 4.6e-07 29.7 17.0 6.7e-07 29.2 17.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srbc PF10316.9 CBY33106.1 - 7.1e-05 22.4 8.9 7.1e-05 22.4 8.9 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc Git3 PF11710.8 CBY33106.1 - 0.96 9.2 16.1 1.4 8.7 16.1 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 zf-C2H2_10 PF16588.5 CBY33107.1 - 0.0049 16.6 1.1 0.015 15.0 1.1 1.9 1 0 0 1 1 1 1 C2H2 zinc-finger Glucosaminidase PF01832.20 CBY33107.1 - 0.041 14.4 0.0 15 6.2 0.0 2.4 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase GAS2 PF02187.17 CBY33108.1 - 1.9e-29 101.5 0.1 4.6e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 CBY33108.1 - 1e-10 41.7 0.2 1.9e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase_Tyr PF07714.17 CBY33110.1 - 6.8e-60 202.5 0.0 1e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33110.1 - 1.8e-52 178.3 0.0 4.1e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY33110.1 - 0.038 12.8 0.2 0.082 11.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Glyco_hydro_125 PF06824.11 CBY33110.1 - 0.12 11.2 0.5 0.19 10.6 0.5 1.2 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) HA PF03457.14 CBY33110.1 - 0.14 12.5 0.8 0.41 11.0 0.8 1.8 1 0 0 1 1 1 0 Helicase associated domain Chorein_N PF12624.7 CBY33112.1 - 4.7e-13 49.3 0.9 2e-12 47.2 0.0 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBY33112.1 - 9.4e-07 28.9 0.3 3.1e-06 27.2 0.3 1.9 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 CBY33113.1 - 9.4e-05 21.9 0.2 0.011 15.1 0.1 3.2 3 1 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CBY33114.1 - 3.3e-22 79.1 1.4 2.1e-21 76.5 0.1 2.3 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal eIF-5_eIF-2B PF01873.17 CBY33114.1 - 0.014 15.3 0.1 0.75 9.7 0.0 2.3 1 1 1 2 2 2 0 Domain found in IF2B/IF5 DUF1757 PF08560.10 CBY33114.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) AMP-binding PF00501.28 CBY33116.1 - 2.7e-85 286.5 0.0 3.3e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY33116.1 - 1.3e-19 70.9 0.0 1.3e-18 67.7 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CBY33116.1 - 4.7e-18 64.9 1.5 1.4e-17 63.4 1.2 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Chorein_N PF12624.7 CBY33117.1 - 1.9e-29 102.1 2.7 3.7e-29 101.2 0.3 2.4 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 CBY33117.1 - 1.7e-07 31.3 0.3 1.4e-06 28.3 0.3 2.2 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal COesterase PF00135.28 CBY33118.1 - 2.5e-21 76.2 0.1 2.7e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY33118.1 - 0.00026 20.9 0.0 0.00026 20.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.20 CBY33119.1 - 4e-12 46.5 0.1 7.6e-10 39.1 0.1 2.4 1 1 1 2 2 2 2 CUB domain Flocculin_t3 PF13928.6 CBY33119.1 - 0.061 13.8 5.8 0.061 13.8 5.8 2.0 2 0 0 2 2 2 0 Flocculin type 3 repeat PilI PF10623.9 CBY33119.1 - 0.15 12.2 0.8 0.61 10.3 0.1 2.4 3 0 0 3 3 3 0 Plasmid conjugative transfer protein PilI Atg14 PF10186.9 CBY33120.1 - 0.0019 17.4 5.4 18 4.3 15.1 2.2 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 CBY33120.1 - 0.26 11.5 16.3 0.77 10.0 5.0 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper Rhodanese PF00581.20 CBY33121.1 - 7.5e-13 48.9 0.0 9.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain adh_short_C2 PF13561.6 CBY33122.1 - 2.1e-54 184.6 0.2 2.6e-54 184.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY33122.1 - 3.9e-47 160.2 0.2 4.7e-47 160.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY33122.1 - 6e-10 39.3 0.1 8.4e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY33122.1 - 0.031 14.9 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 CBY33122.1 - 0.083 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TFIID_30kDa PF03540.13 CBY33123.1 - 6.2e-18 64.5 0.1 1.2e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DSBA PF01323.20 CBY33123.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Septin PF00735.18 CBY33124.1 - 4.7e-125 416.5 0.1 4.7e-125 416.5 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CBY33124.1 - 4.7e-08 33.1 0.0 1.1e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY33124.1 - 3.7e-07 30.2 3.3 4.1e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CBY33124.1 - 2.3e-06 27.3 1.5 0.007 15.9 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CBY33124.1 - 0.00019 20.8 0.1 0.0006 19.2 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 CBY33124.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY33124.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 CBY33124.1 - 0.014 15.9 0.9 0.035 14.6 0.1 1.9 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CBY33124.1 - 0.017 15.4 0.1 0.073 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY33124.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 CBY33124.1 - 0.029 14.9 1.4 0.14 12.6 1.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY33124.1 - 0.099 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CBY33124.1 - 0.11 11.6 1.6 9.6 5.2 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Dynamin_N PF00350.23 CBY33124.1 - 0.22 11.6 7.1 2.5 8.1 0.0 3.2 3 1 1 4 4 4 0 Dynamin family Neur_chan_LBD PF02931.23 CBY33125.1 - 7e-44 149.8 0.2 9.3e-44 149.5 0.2 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY33125.1 - 4.5e-30 105.5 10.9 5.1e-25 88.9 6.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GATA PF00320.27 CBY33127.1 - 1.7e-31 107.5 19.0 3e-16 58.7 5.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY33127.1 - 7e-06 25.5 9.7 0.01 15.3 0.7 2.5 3 0 0 3 3 3 2 TFIIB zinc-binding DUF2387 PF09526.10 CBY33127.1 - 0.0025 17.9 4.1 2.8 8.1 0.2 3.2 1 1 2 3 3 3 1 Probable metal-binding protein (DUF2387) ArfGap PF01412.18 CBY33127.1 - 0.019 15.1 7.9 0.057 13.5 0.6 2.3 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 CBY33127.1 - 0.02 15.1 5.7 0.62 10.3 0.4 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 CBY33127.1 - 0.02 15.0 3.3 3.1 8.0 0.1 2.8 2 1 1 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CBY33127.1 - 0.042 13.8 8.6 1.5 8.8 1.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TDP43_N PF18694.1 CBY33127.1 - 0.058 13.2 0.3 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 CBY33127.1 - 0.076 12.9 5.8 1.6 8.7 1.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 CBY33127.1 - 0.13 12.3 9.4 4.7 7.3 0.8 2.9 1 1 2 3 3 3 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.12 CBY33127.1 - 0.87 9.9 12.7 0.17 12.2 2.3 3.0 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Vps36-NZF-N PF16988.5 CBY33127.1 - 1.3 8.4 9.1 0.24 10.8 0.3 3.2 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cytochrom_c3_2 PF14537.6 CBY33127.1 - 1.5 9.3 7.4 0.6 10.6 1.4 2.2 1 1 1 2 2 2 0 Cytochrome c3 Rubredoxin_2 PF18073.1 CBY33127.1 - 2.2 8.1 12.2 14 5.5 0.1 4.2 4 0 0 4 4 4 0 Rubredoxin metal binding domain Elf1 PF05129.13 CBY33127.1 - 2.6 8.2 9.7 4.2 7.5 0.4 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_15 PF17032.5 CBY33127.1 - 4 8.3 6.1 11 6.9 1.7 2.8 1 1 2 3 3 3 0 zinc-ribbon family zf-ribbon_3 PF13248.6 CBY33127.1 - 4.2 6.9 12.8 4.1 7.0 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Cytochrome_C7 PF14522.6 CBY33127.1 - 8.9 6.4 9.0 51 4.0 9.0 2.2 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c ASD2 PF08687.11 CBY33128.1 - 0.73 9.3 2.4 1 8.9 2.4 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Acyl-CoA_dh_1 PF00441.24 CBY33129.1 - 1.1e-27 97.0 0.2 2.1e-27 96.2 0.2 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY33129.1 - 4.3e-26 91.0 0.0 7.3e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY33129.1 - 1.2e-18 67.8 0.0 2.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY33129.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF3671 PF12420.8 CBY33130.1 - 0.037 14.1 3.6 0.045 13.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function Sre PF03125.18 CBY33130.1 - 0.041 13.0 6.6 0.046 12.9 6.6 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor PMP22_Claudin PF00822.20 CBY33130.1 - 0.056 13.3 2.9 0.067 13.1 2.9 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Rab5ip PF07019.12 CBY33130.1 - 1.8 9.2 7.4 7.1 7.3 7.4 1.8 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) PDZ PF00595.24 CBY33132.1 - 2.8e-16 59.6 0.9 2.5e-14 53.4 0.4 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY33132.1 - 0.00011 22.0 0.0 0.00052 19.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain SAS-6_N PF16531.5 CBY33132.1 - 0.082 13.5 0.6 20 5.8 0.1 2.4 2 0 0 2 2 2 0 Centriolar protein SAS N-terminal PDZ PF00595.24 CBY33133.1 - 8.1e-20 71.0 0.8 1.9e-17 63.4 0.2 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY33133.1 - 6.3e-08 32.4 0.0 9.4e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY33133.1 - 0.00068 19.9 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain EGF_3 PF12947.7 CBY33134.1 - 1.5e-11 44.3 54.8 5.1e-05 23.4 7.9 5.0 4 0 0 4 4 4 4 EGF domain hEGF PF12661.7 CBY33134.1 - 0.0016 19.0 32.1 0.073 13.7 3.2 6.4 5 1 0 5 5 5 4 Human growth factor-like EGF cEGF PF12662.7 CBY33134.1 - 0.0062 16.4 2.5 0.0062 16.4 2.5 5.5 6 1 0 6 6 6 3 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY33134.1 - 0.23 11.7 48.9 0.045 14.0 2.9 5.4 3 1 1 4 4 4 0 Calcium-binding EGF domain EGF PF00008.27 CBY33134.1 - 0.81 10.1 45.2 0.1 12.9 2.2 5.6 4 1 0 4 4 4 0 EGF-like domain LRR_8 PF13855.6 CBY33135.1 - 1.7e-06 27.7 19.0 0.00016 21.4 3.7 4.0 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBY33135.1 - 0.00024 21.4 18.0 0.034 14.6 3.9 4.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY33135.1 - 0.18 11.3 4.0 1.2 8.7 0.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBY33135.1 - 0.49 10.6 12.8 12 6.2 0.5 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBY33135.1 - 2.1 9.2 17.2 17 6.4 1.0 5.8 5 1 1 6 6 6 0 Leucine Rich Repeat ABC1 PF03109.16 CBY33136.1 - 6.1e-32 110.3 0.0 1.2e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family NDUFB10 PF10249.9 CBY33136.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Ras PF00071.22 CBY33137.1 - 1.3e-20 73.6 0.0 1.6e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33137.1 - 5.1e-11 42.9 0.0 8.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY33137.1 - 9.3e-06 25.2 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY33137.1 - 6.3e-05 22.6 0.0 0.0001 21.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY33137.1 - 0.0017 18.3 1.0 2 8.3 0.2 2.6 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY33137.1 - 0.006 16.7 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY33137.1 - 0.014 15.0 0.7 0.43 10.1 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 CBY33137.1 - 0.04 13.3 0.3 5.2 6.5 0.1 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 CBY33137.1 - 0.09 12.5 0.3 1.2 8.8 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Acetyltransf_10 PF13673.7 CBY33138.1 - 1.4e-05 25.0 0.1 2.3e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY33138.1 - 7.1e-05 23.0 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY33138.1 - 0.00026 21.3 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY33138.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CBY33138.1 - 0.11 12.6 0.0 0.38 10.8 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain GAGE PF05831.11 CBY33139.1 - 0.14 12.7 4.2 0.3 11.6 0.8 2.8 1 1 1 2 2 2 0 GAGE protein EGF_CA PF07645.15 CBY33140.1 - 4.8e-06 26.7 2.5 4.8e-06 26.7 2.5 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 CBY33140.1 - 0.48 10.8 14.5 0.82 10.0 6.4 2.7 3 0 0 3 3 3 0 EGF-like domain FXa_inhibition PF14670.6 CBY33140.1 - 1.8 8.9 8.6 8.2 6.8 3.6 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY33140.1 - 3.8 8.3 14.6 7.2 7.4 5.3 3.4 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_3 PF12947.7 CBY33140.1 - 5 7.4 10.0 14 6.0 4.0 2.4 2 0 0 2 2 2 0 EGF domain Trypsin PF00089.26 CBY33141.1 - 3.2e-13 50.0 0.0 5.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin ITI_HC_C PF06668.12 CBY33142.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF3439 PF11921.8 CBY33142.1 - 0.017 15.1 2.2 0.028 14.4 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glycoprotein_G PF00802.19 CBY33142.1 - 0.77 9.1 14.0 1.2 8.4 14.0 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G zf-C4 PF00105.18 CBY33143.1 - 7.4e-32 109.6 12.4 1.4e-31 108.7 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY33143.1 - 1.7e-09 37.5 0.1 5.7e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DUF3736 PF12540.8 CBY33143.1 - 0.98 9.5 7.8 0.28 11.3 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) NAPRTase_C PF17956.1 CBY33143.1 - 2.6 8.5 5.8 0.66 10.4 0.1 2.3 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain TFIIA PF03153.13 CBY33143.1 - 3.9 7.4 13.8 1.2 9.0 10.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CUB PF00431.20 CBY33144.1 - 4.7e-06 26.9 6.5 0.0074 16.6 2.2 3.8 2 1 1 3 3 3 2 CUB domain AAL_decarboxy PF03306.13 CBY33144.1 - 0.06 12.7 0.1 0.12 11.6 0.2 1.4 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase DUF2442 PF10387.9 CBY33144.1 - 0.14 12.5 0.1 0.73 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) NTP_transf_7 PF07984.12 CBY33147.1 - 2.2e-127 424.8 1.2 2.7e-127 424.5 1.2 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Nucleoside_tran PF01733.18 CBY33147.1 - 0.021 14.2 0.3 0.04 13.3 0.3 1.4 1 0 0 1 1 1 0 Nucleoside transporter ASC PF00858.24 CBY33147.1 - 0.043 12.8 0.1 0.043 12.8 0.1 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel OST_IS PF18246.1 CBY33147.1 - 0.13 12.6 0.0 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Oligosaccharyltransferase Insert domain Neur_chan_memb PF02932.16 CBY33148.1 - 7.9e-15 55.6 2.2 1.3e-12 48.3 0.2 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region GST_N PF02798.20 CBY33148.1 - 0.038 14.3 0.0 0.57 10.6 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain CREPT PF16566.5 CBY33148.1 - 0.043 14.0 1.0 0.061 13.5 1.0 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF267 PF03268.14 CBY33148.1 - 0.08 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 Neur_chan_LBD PF02931.23 CBY33149.1 - 4.9e-41 140.5 1.1 5.7e-41 140.3 1.1 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Pga1 PF10333.9 CBY33149.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator zf-H2C2_2 PF13465.6 CBY33150.1 - 5.5e-06 26.6 27.1 0.22 12.0 1.0 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY33150.1 - 1.5e-05 25.2 39.5 0.016 15.7 1.0 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY33150.1 - 8.2e-05 23.1 43.0 0.017 15.9 1.1 6.7 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 CBY33150.1 - 0.046 14.1 0.3 0.046 14.1 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY33150.1 - 5 7.5 18.1 0.11 12.8 1.2 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Strabismus PF06638.11 CBY33151.1 - 1e-26 93.7 0.3 1.3e-26 93.4 0.3 1.0 1 0 0 1 1 1 1 Strabismus protein DUF2842 PF11003.8 CBY33151.1 - 0.15 12.4 5.6 0.29 11.4 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Ldl_recept_b PF00058.17 CBY33153.1 - 1.1e-20 73.8 14.5 0.00015 22.1 0.0 10.0 11 0 0 11 11 11 4 Low-density lipoprotein receptor repeat class B HYR PF02494.16 CBY33153.1 - 5.9e-14 52.2 4.6 6.5e-11 42.4 0.0 4.3 4 1 0 4 4 4 2 HYR domain FXa_inhibition PF14670.6 CBY33153.1 - 6.3e-08 32.8 55.5 3.8e-05 23.9 8.7 5.7 6 0 0 6 6 6 3 Coagulation Factor Xa inhibitory site Ephrin_rec_like PF07699.13 CBY33153.1 - 9.7e-08 31.7 2.5 9.7e-08 31.7 2.5 2.7 1 1 1 2 2 2 1 Putative ephrin-receptor like SGL PF08450.12 CBY33153.1 - 4.1e-05 23.3 2.6 0.72 9.4 0.2 5.5 4 2 1 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region fn1 PF00039.18 CBY33153.1 - 0.00014 21.9 5.8 0.00035 20.7 5.8 1.7 1 0 0 1 1 1 1 Fibronectin type I domain Arylesterase PF01731.20 CBY33153.1 - 0.00017 21.8 0.0 8.1 6.7 0.0 6.3 7 1 0 7 7 7 1 Arylesterase FAM176 PF14851.6 CBY33153.1 - 0.00025 20.7 0.9 0.00025 20.7 0.9 2.2 1 1 1 2 2 1 1 FAM176 family EphA2_TM PF14575.6 CBY33153.1 - 0.0014 19.4 0.1 0.0041 18.0 0.1 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBY33153.1 - 0.11 12.8 0.4 0.28 11.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FAM76 PF16046.5 CBY33153.1 - 0.18 11.2 6.4 0.41 10.0 6.4 1.6 1 0 0 1 1 1 0 FAM76 protein FimA PF16970.5 CBY33153.1 - 0.21 11.8 1.0 0.64 10.2 0.5 2.0 2 0 0 2 2 2 0 Type-1 fimbrial protein, A TMEM51 PF15345.6 CBY33153.1 - 0.62 9.9 7.9 0.11 12.3 1.5 2.2 1 1 1 2 2 2 0 Transmembrane protein 51 EGF PF00008.27 CBY33153.1 - 3.3 8.1 38.0 1.5 9.2 8.9 4.8 4 0 0 4 4 4 0 EGF-like domain Pkinase PF00069.25 CBY33154.1 - 6.5e-08 32.3 2.6 2.6e-07 30.3 0.0 2.7 2 1 1 3 3 3 1 Protein kinase domain DUF724 PF05266.14 CBY33154.1 - 0.0094 15.8 6.9 0.0094 15.8 6.9 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF724) Fib_alpha PF08702.10 CBY33154.1 - 0.02 15.1 5.1 0.79 9.9 3.4 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Elf4 PF07011.11 CBY33154.1 - 0.063 13.2 0.3 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 Early Flowering 4 domain Tiam_CC_Ex PF18385.1 CBY33154.1 - 0.13 12.6 0.7 0.41 11.1 0.7 1.9 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain V_ATPase_I PF01496.19 CBY33154.1 - 0.33 8.8 10.6 0.5 8.2 10.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pex26 PF07163.12 CBY33154.1 - 0.54 9.5 1.7 4.6 6.5 0.6 2.3 2 0 0 2 2 2 0 Pex26 protein FOXP-CC PF16159.5 CBY33154.1 - 2.5 8.8 4.4 3 8.5 0.4 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain FAM76 PF16046.5 CBY33154.1 - 2.9 7.2 13.9 18 4.6 0.2 2.4 1 1 1 2 2 2 0 FAM76 protein Golgin_A5 PF09787.9 CBY33154.1 - 4 6.8 24.4 0.36 10.2 19.7 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cnn_1N PF07989.11 CBY33154.1 - 9.5 6.5 21.1 0.18 12.0 8.7 3.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spectrin PF00435.21 CBY33155.1 - 0.0025 18.3 1.2 0.0025 18.3 1.2 20.7 13 3 7 21 21 21 7 Spectrin repeat GAPES1 PF17155.4 CBY33155.1 - 0.0044 16.4 0.3 0.01 15.2 0.3 1.5 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain FAA_hydrolase_N PF09298.11 CBY33155.1 - 7.5 6.8 6.7 11 6.3 0.1 4.9 5 1 0 5 5 5 0 Fumarylacetoacetase N-terminal Endonuclease_NS PF01223.23 CBY33158.1 - 5.2e-08 33.0 0.1 8.7e-08 32.2 0.1 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.23 CBY33159.1 - 0.0096 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pkinase_Tyr PF07714.17 CBY33160.1 - 9.1e-39 133.3 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33160.1 - 1e-23 84.1 0.0 1.8e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBY33161.1 - 2.1e-33 115.8 0.0 3.3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33161.1 - 2.9e-27 95.6 0.0 7.1e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 CBY33161.1 - 0.00058 19.3 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Transforming growth factor beta type I GS-motif Pkinase_fungal PF17667.1 CBY33161.1 - 0.0041 15.9 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase She2p PF11435.8 CBY33162.1 - 0.031 14.0 0.2 0.067 12.9 0.0 1.7 2 0 0 2 2 2 0 RNA binding protein She2p OTOS PF15182.6 CBY33162.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Otospiralin RVT_1 PF00078.27 CBY33163.1 - 3.4e-33 115.0 1.1 9.5e-33 113.6 0.0 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavi_capsid PF01003.19 CBY33163.1 - 0.17 11.7 1.2 0.87 9.4 0.2 2.5 2 0 0 2 2 2 0 Flavivirus capsid protein C Ras PF00071.22 CBY33165.1 - 2.1e-52 177.0 0.0 2.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33165.1 - 9.4e-20 71.0 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY33165.1 - 1.9e-09 37.2 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY33165.1 - 0.0013 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY33165.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBY33165.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Gtr1_RagA PF04670.12 CBY33165.1 - 0.044 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Thioredoxin PF00085.20 CBY33167.1 - 6.1e-58 193.2 0.2 1.9e-31 108.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY33167.1 - 2.8e-34 118.6 0.0 3e-27 95.7 0.3 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY33167.1 - 2e-08 34.6 0.8 1.2e-06 28.9 0.0 3.4 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY33167.1 - 2.2e-07 31.0 0.0 0.0049 17.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY33167.1 - 5.3e-06 26.7 0.0 0.096 13.0 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY33167.1 - 0.00015 21.2 0.0 0.0086 15.5 0.0 2.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 CBY33167.1 - 0.0021 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 CBY33167.1 - 0.0029 17.5 0.2 2.4 8.1 0.0 3.0 2 1 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 CBY33167.1 - 0.0068 16.5 0.0 0.15 12.2 0.0 3.0 3 1 0 3 3 3 1 ERp29, N-terminal domain Redoxin PF08534.10 CBY33167.1 - 0.0069 16.1 0.1 1.9 8.2 0.0 2.8 3 0 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 CBY33167.1 - 0.017 15.1 0.2 7 6.8 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain Guanylate_kin PF00625.21 CBY33168.1 - 2.2e-61 206.7 0.0 2.7e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CBY33168.1 - 0.00017 22.2 0.5 0.0017 18.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY33168.1 - 0.00022 21.6 0.0 0.00036 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CBY33168.1 - 0.0003 21.1 0.0 0.0021 18.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CBY33168.1 - 0.00039 20.6 0.5 0.013 15.6 0.5 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY33168.1 - 0.00088 19.2 0.1 0.0027 17.6 0.0 1.8 2 1 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 CBY33168.1 - 0.0078 16.2 0.0 0.75 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CBY33168.1 - 0.017 14.8 0.1 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY33168.1 - 0.025 14.9 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBY33168.1 - 0.03 14.8 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 CBY33168.1 - 0.033 14.6 0.3 0.095 13.1 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBY33168.1 - 0.035 14.0 0.1 0.057 13.3 0.1 1.5 1 1 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 CBY33168.1 - 0.041 14.0 0.1 0.081 13.0 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 CBY33168.1 - 0.05 13.5 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_7 PF12775.7 CBY33168.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CBY33168.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBY33168.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CBY33168.1 - 0.06 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 CBY33168.1 - 0.07 12.8 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CBY33168.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY33168.1 - 0.078 13.4 0.9 0.93 9.9 0.9 2.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBY33168.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CBY33168.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 CBY33168.1 - 0.15 12.2 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 CBY33169.1 - 5.4e-160 532.3 0.1 7.5e-160 531.9 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBY33169.1 - 5e-26 90.6 0.1 1.7e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBY33169.1 - 1.7e-09 38.2 0.0 1.6e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY33169.1 - 8.4e-08 32.1 0.1 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBY33169.1 - 1.5e-05 25.3 0.1 0.073 13.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CBY33169.1 - 3e-05 23.7 0.0 0.00071 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY33169.1 - 0.00015 22.2 0.0 0.023 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY33169.1 - 0.00032 20.7 0.1 0.046 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBY33169.1 - 0.0049 16.3 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBY33169.1 - 0.0065 16.2 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 CBY33169.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 CBY33169.1 - 0.022 15.1 2.0 0.56 10.5 1.5 2.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY33169.1 - 0.037 14.6 0.0 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBY33169.1 - 0.046 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 CBY33169.1 - 0.052 13.0 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 CBY33169.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY33169.1 - 0.095 12.2 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TFIID-31kDa PF02291.15 CBY33169.1 - 0.13 12.4 0.1 0.97 9.5 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit NACHT PF05729.12 CBY33169.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Peptidase_M14 PF00246.24 CBY33170.1 - 1.8e-98 329.9 0.1 5.2e-62 210.3 0.1 3.1 3 0 0 3 3 3 3 Zinc carboxypeptidase DUF4734 PF15881.5 CBY33170.1 - 0.0084 16.3 1.5 3.2 8.0 0.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4734) Ras PF00071.22 CBY33171.1 - 1.6e-53 180.6 0.0 1.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33171.1 - 3.8e-26 91.7 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY33171.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY33171.1 - 0.00027 20.4 0.0 0.00036 20.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY33171.1 - 0.00045 19.8 0.1 0.00084 18.9 0.1 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY33171.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY33171.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ldh_1_N PF00056.23 CBY33171.1 - 0.067 13.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Pdase_M17_N2 PF18295.1 CBY33171.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Lipase_GDSL_3 PF14606.6 CBY33171.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TniB PF05621.11 CBY33171.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Herpes_UL1 PF05259.11 CBY33172.1 - 0.032 14.3 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Anp1 PF03452.14 CBY33173.1 - 0.045 13.2 0.0 3.5 7.0 0.0 2.3 1 1 1 2 2 2 0 Anp1 2OG-FeII_Oxy_3 PF13640.6 CBY33174.1 - 6.6e-09 36.5 0.0 8.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 CBY33174.1 - 0.022 14.5 0.1 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Cupin domain KIP1 PF07765.12 CBY33175.1 - 0.025 14.7 0.1 0.075 13.2 0.1 1.8 1 0 0 1 1 1 0 KIP1-like protein IQ PF00612.27 CBY33176.1 - 0.22 11.4 8.7 2.7 8.0 0.1 3.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif PI-PLC-X PF00388.19 CBY33177.1 - 2.5e-32 111.5 0.1 4.7e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY33177.1 - 1.5e-27 96.2 0.0 4e-27 94.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CBY33177.1 - 4.9e-13 49.4 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 CBY33177.1 - 7.3e-13 48.7 0.0 2.1e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH_12 PF16457.5 CBY33177.1 - 4.2e-12 46.7 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY33177.1 - 0.0023 18.4 0.2 0.0065 17.0 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_14 PF17787.1 CBY33177.1 - 0.0038 17.1 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 CBY33177.1 - 0.0048 17.3 0.1 0.021 15.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Mcp5_PH PF12814.7 CBY33177.1 - 0.0087 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.32 CBY33177.1 - 0.034 13.7 0.1 0.08 12.5 0.1 1.7 1 0 0 1 1 1 0 EF hand Aa_trans PF01490.18 CBY33178.1 - 5e-11 41.9 5.4 5.7e-11 41.8 5.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY33178.1 - 0.00016 20.8 2.5 0.0002 20.5 2.5 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBY33179.1 - 8.6e-40 136.7 15.9 1.1e-39 136.3 15.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TatC PF00902.18 CBY33179.1 - 0.061 13.1 13.9 0.13 12.1 13.9 1.6 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Cdc13_OB2 PF18691.1 CBY33179.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain Connexin PF00029.19 CBY33180.1 - 2.4e-36 125.7 6.2 3.2e-36 125.3 6.2 1.1 1 0 0 1 1 1 1 Connexin Halogen_Hydrol PF10112.9 CBY33180.1 - 0.11 12.5 0.1 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RabGAP-TBC PF00566.18 CBY33182.1 - 1.1e-50 172.3 1.5 1.4e-50 171.9 1.5 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phospholip_A2_1 PF00068.19 CBY33183.1 - 1.2e-17 64.4 8.9 1.2e-17 64.4 8.9 1.6 2 0 0 2 2 2 1 Phospholipase A2 AMP-binding PF00501.28 CBY33184.1 - 3.2e-93 312.6 0.0 4.3e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ELO PF01151.18 CBY33185.1 - 2.9e-50 171.1 16.5 3.5e-50 170.9 16.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MerC PF03203.14 CBY33185.1 - 0.077 13.4 6.7 1.9 8.9 3.3 2.6 1 1 1 2 2 2 0 MerC mercury resistance protein CBM_14 PF01607.24 CBY33186.1 - 1e-29 102.4 17.2 2.6e-15 56.3 4.4 2.1 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain Baculo_VP91_N PF08475.10 CBY33186.1 - 0.44 10.2 3.8 0.44 10.2 0.6 1.9 1 1 1 2 2 2 0 Viral capsid protein 91 N-terminal DUF5401 PF17380.2 CBY33186.1 - 1.1 7.3 5.5 3.4 5.6 1.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5401) PIH1 PF08190.12 CBY33187.1 - 2.8e-27 95.2 0.1 5.7e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBY33187.1 - 2e-08 34.6 0.1 5.1e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain NTP_transferase PF00483.23 CBY33188.1 - 1.6e-20 73.7 0.0 5.8e-20 71.9 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CBY33188.1 - 6.5e-11 42.8 0.0 7.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 CBY33188.1 - 0.00011 22.1 0.0 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pkinase PF00069.25 CBY33189.1 - 2e-61 207.7 0.0 5.1e-60 203.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33189.1 - 6.6e-25 87.9 0.0 1.7e-23 83.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33189.1 - 4.3e-07 29.5 0.0 2.7e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBY33189.1 - 0.00049 19.2 0.0 0.0083 15.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY33189.1 - 0.0048 16.9 0.2 0.016 15.1 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY33189.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 CBY33189.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY33189.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY33189.1 - 0.11 12.1 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SfsA PF03749.13 CBY33189.1 - 0.11 12.4 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Sugar fermentation stimulation protein RE domain CHGN PF05679.16 CBY33190.1 - 1.7e-142 475.9 0.0 2.1e-142 475.6 0.0 1.1 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase AhpC-TSA PF00578.21 CBY33191.1 - 1.3e-39 134.9 0.0 5e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBY33191.1 - 6.5e-17 61.6 0.0 8.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY33191.1 - 4.8e-13 48.7 0.1 8.2e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBY33191.1 - 0.025 14.5 0.1 0.055 13.4 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Ssl1 PF04056.14 CBY33192.1 - 1.9e-43 148.5 0.0 2.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CBY33192.1 - 5.4e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C1_4 PF07975.12 CBY33192.1 - 7.4e-05 22.9 18.4 0.00018 21.7 13.6 3.0 2 1 1 3 3 3 1 TFIIH C1-like domain IBR PF01485.21 CBY33192.1 - 0.028 14.6 2.9 0.028 14.6 2.9 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-UDP PF14569.6 CBY33192.1 - 0.83 9.8 11.6 1.2 9.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 CBY33192.1 - 0.96 9.5 16.1 0.095 12.7 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 CBY33192.1 - 7.3 7.4 9.8 7.4 7.4 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon family zf-C3HC4_4 PF15227.6 CBY33192.1 - 9.2 6.5 13.5 43 4.4 0.1 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ADH_zinc_N PF00107.26 CBY33193.1 - 9.1e-22 77.4 0.1 1.7e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY33193.1 - 6e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CBY33193.1 - 0.056 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_kinase PF01513.21 CBY33194.1 - 5.5e-65 219.4 0.0 6.8e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CBY33194.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cauli_VI PF01693.16 CBY33195.1 - 7.4e-36 122.2 10.2 6.2e-18 64.8 0.7 3.3 3 0 0 3 3 3 2 Caulimovirus viroplasmin RNase_H PF00075.24 CBY33195.1 - 1.7e-27 96.4 0.1 3.6e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CBY33195.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Brix PF04427.18 CBY33196.1 - 2.4e-38 132.2 0.1 3.4e-38 131.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain Cation_efflux PF01545.21 CBY33197.1 - 3.4e-28 98.7 8.2 4.2e-28 98.5 8.2 1.1 1 0 0 1 1 1 1 Cation efflux family 2OG-FeII_Oxy_2 PF13532.6 CBY33198.1 - 9.9e-20 71.6 0.0 1.6e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4543 PF15076.6 CBY33198.1 - 0.052 13.7 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) eIF3_N PF09440.10 CBY33200.1 - 0.098 13.1 0.0 2.2 8.7 0.0 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Aldedh PF00171.22 CBY33202.1 - 7.1e-160 532.5 0.0 8.2e-160 532.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBY33202.1 - 0.00045 19.7 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RGS PF00615.19 CBY33203.1 - 4e-20 72.2 0.4 2.6e-07 30.9 0.0 4.1 3 0 0 3 3 3 3 Regulator of G protein signaling domain Ammonium_transp PF00909.21 CBY33203.1 - 0.3 9.7 0.0 0.4 9.3 0.0 1.1 1 0 0 1 1 1 0 Ammonium Transporter Family Peptidase_C97 PF05903.14 CBY33206.1 - 2.5e-11 43.7 0.3 3.6e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4300 PF14133.6 CBY33206.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF4796 PF16044.5 CBY33206.1 - 0.13 11.8 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Pox_EPC_I2-L1 PF12575.8 CBY33206.1 - 0.16 12.2 0.1 0.33 11.2 0.0 1.6 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Peptidase_M24 PF00557.24 CBY33207.1 - 2.5e-08 33.9 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 CBY33208.1 - 1.5e-08 34.6 0.0 1.5e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4312 PF14189.6 CBY33208.1 - 0.089 12.8 0.1 1.7 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4312) AMP_N PF05195.16 CBY33209.1 - 7.1e-29 100.0 0.1 1.1e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CBY33209.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 DUF1262 PF06880.11 CBY33209.1 - 0.11 12.9 0.1 11 6.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1262) bZIP_1 PF00170.21 CBY33210.1 - 3.8e-08 33.3 14.2 7.6e-08 32.3 14.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY33210.1 - 0.00016 21.7 14.8 0.00031 20.8 14.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.11 CBY33210.1 - 0.049 13.0 1.2 0.083 12.3 1.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M polyprenyl_synt PF00348.17 CBY33211.1 - 4.5e-67 225.8 0.0 5.4e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DSX_dimer PF08828.10 CBY33211.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain RNA_pol_Rpb1_5 PF04998.17 CBY33212.1 - 5.2e-81 272.0 0.0 9.3e-81 271.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 CBY33212.1 - 2.4e-12 46.7 0.0 9.8e-12 44.8 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 CBY33212.1 - 2.2e-06 27.7 0.4 6.3e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 BUD22 PF09073.10 CBY33212.1 - 0.46 9.8 11.2 0.87 8.9 11.2 1.4 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpb1_2 PF00623.20 CBY33213.1 - 0.00046 20.5 0.1 0.00063 20.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBY33213.1 - 0.067 13.1 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CBY33215.1 - 8.2e-25 87.8 1.1 1.5e-24 86.9 1.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DUF4515 PF14988.6 CBY33217.1 - 2e-05 24.6 29.7 2e-05 24.6 29.7 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4515) DUF3300 PF11737.8 CBY33217.1 - 0.11 12.0 1.8 0.16 11.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF936 PF06075.12 CBY33217.1 - 0.29 10.0 14.4 0.36 9.7 14.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) LOH1CR12 PF10158.9 CBY33217.1 - 7.7 6.6 16.8 0.28 11.2 4.7 2.2 1 1 0 2 2 2 0 Tumour suppressor protein APG6_N PF17675.1 CBY33217.1 - 9.6 6.7 34.1 1.1 9.8 16.9 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Longin PF13774.6 CBY33218.1 - 4.2e-05 23.5 0.9 6.7e-05 22.9 0.2 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain MRP-S28 PF10213.9 CBY33219.1 - 0.045 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Acyl-CoA_dh_1 PF00441.24 CBY33220.1 - 7.6e-43 146.3 0.0 1.2e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY33220.1 - 8.6e-33 113.4 0.0 1.5e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY33220.1 - 5.9e-27 93.7 0.1 1.2e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY33220.1 - 1e-13 51.8 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY33220.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Gal-3-0_sulfotr PF06990.11 CBY33221.1 - 2.9e-38 131.8 0.3 5.5e-37 127.6 0.3 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY33221.1 - 7.2e-07 29.4 3.6 1.2e-05 25.3 3.6 2.7 1 1 0 1 1 1 1 Sulfotransferase family IMCp PF12314.8 CBY33221.1 - 0.009 16.3 0.4 0.009 16.3 0.4 1.9 2 0 0 2 2 2 1 Inner membrane complex protein PAS_10 PF13596.6 CBY33221.1 - 0.067 13.8 0.2 0.31 11.7 0.0 2.0 2 0 0 2 2 2 0 PAS domain MitMem_reg PF13012.6 CBY33223.1 - 0.11 12.9 0.1 5.9 7.3 0.0 3.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4065 PF13274.6 CBY33223.1 - 0.28 12.1 4.2 0.28 12.1 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) CUB PF00431.20 CBY33224.1 - 3.5e-138 452.2 18.8 4.3e-21 75.3 0.0 9.8 9 1 0 9 9 9 9 CUB domain EGF PF00008.27 CBY33224.1 - 2.4e-06 27.7 111.8 7.8e-06 26.1 8.6 9.4 8 0 0 8 8 8 6 EGF-like domain EGF_3 PF12947.7 CBY33224.1 - 1.6e-05 25.0 99.9 0.00014 22.0 9.0 8.1 8 1 0 8 8 8 6 EGF domain EGF_CA PF07645.15 CBY33224.1 - 0.00042 20.5 7.5 0.00042 20.5 7.5 8.6 5 3 3 8 8 8 2 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY33224.1 - 0.0099 16.1 9.8 0.0099 16.1 9.8 9.1 7 2 3 10 10 10 3 Coagulation Factor Xa inhibitory site PAP2 PF01569.21 CBY33225.1 - 1.4e-23 83.2 2.3 3.4e-23 81.9 0.9 2.2 2 1 0 2 2 2 1 PAP2 superfamily Cation_efflux PF01545.21 CBY33225.1 - 0.00053 19.8 0.2 0.0053 16.5 0.1 2.1 2 0 0 2 2 2 1 Cation efflux family DUF4234 PF14018.6 CBY33225.1 - 0.014 15.5 0.8 0.05 13.7 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF212 PF02681.14 CBY33225.1 - 0.48 10.6 2.4 8 6.6 0.1 2.5 3 0 0 3 3 3 0 Divergent PAP2 family DUF485 PF04341.12 CBY33225.1 - 1.5 8.9 4.1 14 5.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 ATP_transf PF09830.9 CBY33226.1 - 0.17 12.1 0.4 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 ATP adenylyltransferase Enkurin PF13864.6 CBY33226.1 - 0.3 11.5 7.7 0.35 11.3 0.1 3.1 2 1 1 3 3 3 0 Calmodulin-binding Enkurin PF13864.6 CBY33227.1 - 4.8e-16 59.0 0.2 5.7e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 Calmodulin-binding Cob_adeno_trans PF01923.18 CBY33227.1 - 0.049 13.8 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ABC_tran_CTD PF16326.5 CBY33227.1 - 0.098 12.9 5.7 0.81 10.0 1.2 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain IDEAL PF08858.10 CBY33227.1 - 0.16 11.8 2.8 33 4.3 0.1 3.1 3 0 0 3 3 3 0 IDEAL domain SecE PF00584.20 CBY33228.1 - 5.6e-14 51.8 0.2 6.3e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Zona_pellucida PF00100.23 CBY33229.1 - 1.2e-16 61.3 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Podoplanin PF05808.11 CBY33230.1 - 0.00056 20.1 1.9 0.0013 18.8 1.9 1.6 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.13 CBY33230.1 - 0.02 15.5 3.4 0.049 14.2 3.4 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J CC190 PF15768.5 CBY33230.1 - 0.035 14.2 1.6 0.083 12.9 1.6 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 TMEM154 PF15102.6 CBY33230.1 - 0.061 13.2 4.5 0.17 11.8 4.5 1.8 1 0 0 1 1 1 0 TMEM154 protein family LEA_6 PF10714.9 CBY33230.1 - 0.18 11.9 2.0 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein 18 BES1_N PF05687.13 CBY33230.1 - 0.23 11.8 9.1 0.67 10.3 9.1 1.7 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF5305 PF17231.2 CBY33230.1 - 0.43 10.0 3.2 0.75 9.2 3.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Miga PF10265.9 CBY33230.1 - 4.4 6.2 7.8 8 5.3 7.8 1.3 1 0 0 1 1 1 0 Mitoguardin ADH_zinc_N PF00107.26 CBY33231.1 - 4.3e-12 46.1 0.1 1e-11 44.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBY33231.1 - 6.7e-09 35.6 0.3 4.7e-08 32.9 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBY33231.1 - 2.3e-07 31.9 0.0 4.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VWD PF00094.25 CBY33232.1 - 2.9e-26 92.6 0.1 4.6e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 CBY33232.1 - 1.3e-16 60.7 4.5 1.3e-16 60.7 4.5 3.3 2 1 1 3 3 3 1 C8 domain TIL PF01826.17 CBY33232.1 - 2.2e-09 37.4 17.6 2.2e-09 37.4 17.6 5.2 5 1 1 6 6 6 1 Trypsin Inhibitor like cysteine rich domain Somatomedin_B PF01033.17 CBY33232.1 - 0.00021 21.6 21.3 0.00021 21.6 21.3 5.5 4 2 0 4 4 4 1 Somatomedin B domain LRR_6 PF13516.6 CBY33233.1 - 5.5e-21 72.8 14.9 0.023 14.7 0.0 8.5 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 CBY33233.1 - 0.00019 21.5 11.3 4 8.4 0.0 7.2 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 CBY33233.1 - 0.074 13.5 22.1 0.69 10.4 1.4 5.5 1 1 6 7 7 7 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY33233.1 - 0.21 11.4 20.1 0.48 10.2 3.8 5.6 3 1 3 6 6 6 0 Leucine rich repeat Nucleoside_tran PF01733.18 CBY33234.1 - 3.4e-19 69.4 1.9 6.8e-19 68.4 1.9 1.4 1 0 0 1 1 1 1 Nucleoside transporter Sigma70_r4_2 PF08281.12 CBY33234.1 - 0.019 14.6 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 GCIP PF13324.6 CBY33234.1 - 3.2 7.3 7.3 7.3 6.1 7.3 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MADF_DNA_bdg PF10545.9 CBY33234.1 - 6.2 7.2 11.0 5.7 7.3 0.1 4.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Trypsin PF00089.26 CBY33236.1 - 1.4e-08 34.9 1.4 2.8e-07 30.6 1.4 2.4 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY33236.1 - 0.083 13.3 0.3 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) GTP_EFTU PF00009.27 CBY33237.1 - 1.5e-20 73.5 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY33237.1 - 0.0004 20.7 1.8 0.0049 17.2 1.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 CBY33237.1 - 0.003 17.3 0.6 1.2 8.9 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CBY33237.1 - 0.0041 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBY33237.1 - 0.028 14.7 0.3 12 6.2 0.1 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CBY33237.1 - 0.029 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CENP-T_C PF15511.6 CBY33239.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY33239.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY33239.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY33239.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY33239.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY33239.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY33239.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY33239.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RabGAP-TBC PF00566.18 CBY33240.1 - 5.4e-41 140.6 0.1 8.5e-41 140.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.10 CBY33240.1 - 0.023 14.4 0.1 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 UTP15 C terminal NYD-SP28_assoc PF14775.6 CBY33240.1 - 0.17 12.0 0.9 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain PH_RBD PF12068.8 CBY33241.1 - 0.0019 17.7 0.0 0.042 13.3 0.0 2.0 1 1 1 2 2 2 2 Rab-binding domain (RBD) Histone_H2A_C PF16211.5 CBY33242.1 - 1.9e-20 72.3 1.3 4.1e-20 71.2 1.3 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY33242.1 - 4.5e-16 59.4 0.0 5.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY33242.1 - 3.9e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY33243.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY33243.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY33243.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY33243.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY33243.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein SURF4 PF02077.15 CBY33244.1 - 2.8e-72 243.5 10.2 3.2e-72 243.3 10.2 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY33244.1 - 0.00029 21.4 2.1 0.00029 21.4 2.1 3.3 3 1 1 4 4 4 2 DoxX HR_lesion PF05514.11 CBY33244.1 - 0.14 12.3 12.7 1.1 9.4 1.4 3.0 2 1 0 2 2 2 0 HR-like lesion-inducing EF-hand_6 PF13405.6 CBY33246.1 - 1.8e-24 83.5 1.8 5.2e-06 26.0 0.2 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY33246.1 - 3.8e-24 84.9 3.1 4.8e-16 59.0 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY33246.1 - 9.4e-24 81.2 9.2 2.7e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CBY33246.1 - 8e-18 63.1 11.1 0.0001 21.6 0.8 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CBY33246.1 - 1.5e-14 53.5 6.5 8e-06 25.6 0.3 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY33246.1 - 9.7e-07 28.7 1.0 0.44 10.5 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY33246.1 - 0.0002 21.6 0.4 0.34 11.2 0.0 3.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 CBY33246.1 - 0.0028 18.0 0.0 0.014 15.8 0.0 2.0 2 1 0 2 2 2 1 EF-hand EF-hand_9 PF14658.6 CBY33246.1 - 0.0046 17.2 0.0 0.082 13.2 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain Sulfotransfer_2 PF03567.14 CBY33247.1 - 0.00031 20.8 0.8 0.00046 20.2 0.8 1.3 1 0 0 1 1 1 1 Sulfotransferase family zf-C4 PF00105.18 CBY33248.1 - 4.8e-10 39.8 2.6 9.2e-10 38.8 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.12 CBY33248.1 - 0.081 13.0 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 ChaC-like protein Glutaminase PF04960.15 CBY33249.1 - 2.4e-83 279.7 0.5 3.1e-83 279.3 0.5 1.2 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 CBY33249.1 - 2.2e-13 50.6 0.0 4.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY33249.1 - 4e-09 36.8 0.2 4.1e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33249.1 - 3.4e-07 30.0 0.1 0.25 12.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CBY33249.1 - 0.00036 20.8 0.3 0.92 9.9 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY33249.1 - 0.00066 20.0 0.0 3.9 8.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat EF-hand_14 PF17959.1 CBY33250.1 - 9.6e-08 32.3 0.2 2e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain Ldl_recept_a PF00057.18 CBY33251.1 - 4.2e-54 180.5 135.4 4.1e-09 36.5 15.2 9.0 7 1 1 8 8 8 8 Low-density lipoprotein receptor domain class A Trypsin PF00089.26 CBY33251.1 - 6.6e-49 166.7 0.0 1.1e-48 166.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin Fz PF01392.22 CBY33251.1 - 6.2e-11 42.9 19.4 6.2e-11 42.9 19.4 5.9 4 3 0 4 4 4 1 Fz domain FA_hydroxylase PF04116.13 CBY33252.1 - 7.4e-24 84.6 12.6 7.4e-24 84.6 12.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Phospholip_A2_1 PF00068.19 CBY33253.1 - 2.9e-11 43.8 0.2 4.1e-11 43.3 0.2 1.2 1 0 0 1 1 1 1 Phospholipase A2 Metallophos PF00149.28 CBY33254.1 - 1.7e-11 45.0 0.1 2.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribos_L4_asso_C PF14374.6 CBY33256.1 - 4.3e-26 90.8 4.8 4.3e-26 90.8 4.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.22 CBY33256.1 - 3.6e-25 88.8 0.1 6e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Lung_7-TM_R PF06814.13 CBY33257.1 - 7.7e-62 209.2 15.0 9.8e-62 208.8 15.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CcmB PF03379.13 CBY33257.1 - 0.024 14.2 3.1 0.16 11.5 0.7 2.2 2 0 0 2 2 2 0 CcmB protein DUF2681 PF10883.8 CBY33257.1 - 0.13 12.7 1.9 23 5.5 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Ost5 PF05251.12 CBY33257.1 - 4.9 7.5 6.9 27 5.1 0.2 2.8 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF2231 PF09990.9 CBY33257.1 - 9.3 6.7 10.9 3.3 8.2 0.6 3.3 3 1 1 4 4 4 0 Predicted membrane protein (DUF2231) PITH PF06201.13 CBY33258.1 - 3.5e-39 134.5 1.2 5.2e-39 133.9 1.2 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CBY33258.1 - 5e-24 84.3 0.1 1.2e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY33258.1 - 0.0017 18.7 0.4 0.053 14.0 0.4 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBY33258.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBY33258.1 - 0.01 16.1 0.0 0.15 12.4 0.0 2.6 2 1 1 3 3 3 0 Thioredoxin-like DUF1779 PF08680.10 CBY33258.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TATA-box binding HyaE PF07449.11 CBY33258.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PDZ_2 PF13180.6 CBY33259.1 - 1.8e-06 28.1 0.0 6.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBY33259.1 - 7.6e-06 25.7 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY33259.1 - 1.8e-05 25.0 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Myb_DNA-binding PF00249.31 CBY33259.1 - 0.0002 21.5 0.1 0.00045 20.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY33259.1 - 0.0011 19.1 0.2 0.003 17.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY33259.1 - 0.0047 16.8 0.3 0.021 14.7 0.3 2.2 1 0 0 1 1 1 1 Myb DNA-binding like SLIDE PF09111.10 CBY33259.1 - 0.04 13.9 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 SLIDE Sec1 PF00995.23 CBY33261.1 - 1.4e-09 37.8 0.0 1.6e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 CBY33262.1 - 2.2e-61 208.8 0.0 1.1e-33 117.4 0.0 2.0 1 1 1 2 2 2 2 Sec1 family DiSB-ORF2_chro PF16506.5 CBY33262.1 - 0.026 14.5 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative virion glycoprotein of insect viruses CH PF00307.31 CBY33263.1 - 4.6e-21 75.1 0.1 3.4e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain RRM_1 PF00076.22 CBY33264.1 - 8.8e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCP_C_terminal PF04130.13 CBY33265.1 - 7.9e-58 196.3 1.7 1.4e-57 195.6 1.7 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBY33265.1 - 7.6e-42 144.0 0.5 1.5e-41 143.0 0.5 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal TUDOR PF00567.24 CBY33266.1 - 1.4e-07 31.5 0.1 4.7e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain Not3 PF04065.15 CBY33267.1 - 5e-72 242.1 26.5 5e-72 242.1 26.5 1.9 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component DUF2433 PF10360.9 CBY33267.1 - 1 9.5 5.5 0.35 11.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) HR1 PF02185.16 CBY33267.1 - 3.3 7.9 11.5 0.71 10.0 2.8 2.7 2 0 0 2 2 2 0 Hr1 repeat DUF1682 PF07946.14 CBY33268.1 - 0.023 13.9 0.0 0.026 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Polysacc_synt_C PF14667.6 CBY33269.1 - 3.6 7.7 12.9 16 5.6 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.32 CBY33271.1 - 3.6e-16 59.3 1.9 3.4e-11 43.5 0.0 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY33271.1 - 5.2e-09 36.3 0.1 3.1e-08 33.8 0.1 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY33271.1 - 0.092 12.6 0.1 0.33 10.8 0.1 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CBY33275.1 - 1.4e-18 66.8 8.2 7.1e-11 42.5 0.0 4.5 3 2 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY33275.1 - 9.8e-12 45.0 0.3 2.9e-07 30.7 0.1 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY33275.1 - 0.077 12.9 0.1 0.24 11.2 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF2218 PF09981.9 CBY33275.1 - 0.13 12.7 0.0 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) CIA30 PF08547.12 CBY33276.1 - 4.5e-26 91.8 0.4 5.6e-26 91.5 0.4 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 CBY33276.1 - 0.0012 18.8 0.3 0.0019 18.2 0.2 1.3 1 1 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain MFS_1 PF07690.16 CBY33278.1 - 4e-34 118.1 44.9 7.5e-29 100.8 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phospholip_A2_1 PF00068.19 CBY33279.1 - 0.0075 16.7 1.6 0.0075 16.7 1.6 2.1 2 1 0 2 2 2 1 Phospholipase A2 DUF2325 PF10087.9 CBY33280.1 - 0.065 13.4 0.2 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF4599 PF15371.6 CBY33280.1 - 0.2 12.2 3.3 6.1 7.5 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4599) RbsD_FucU PF05025.13 CBY33280.1 - 0.28 11.6 2.3 0.53 10.7 2.3 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family bZIP_1 PF00170.21 CBY33280.1 - 0.28 11.3 16.8 0.16 12.1 7.8 3.0 1 1 2 3 3 3 0 bZIP transcription factor Ly49 PF08391.10 CBY33280.1 - 1.4 9.3 6.2 3.5 8.0 6.2 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Uso1_p115_C PF04871.13 CBY33280.1 - 2.3 8.6 17.8 0.066 13.6 9.7 2.4 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 CBY33280.1 - 4.1 7.2 13.8 0.73 9.6 9.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPD52 PF04201.15 CBY33280.1 - 6.4 6.4 12.9 0.11 12.1 4.3 2.4 2 1 1 3 3 3 0 Tumour protein D52 family CENP-H PF05837.12 CBY33280.1 - 6.8 7.1 11.5 1.8 9.0 7.8 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) THOC7 PF05615.13 CBY33280.1 - 9.9 6.5 17.1 2.8 8.2 1.7 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 Aldo_ket_red PF00248.21 CBY33281.1 - 2.9e-22 79.2 0.0 1.7e-20 73.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Zona_pellucida PF00100.23 CBY33282.1 - 1.5e-18 67.6 0.1 1.5e-18 67.6 0.1 1.8 2 0 0 2 2 2 1 Zona pellucida-like domain Sushi PF00084.20 CBY33282.1 - 0.054 14.1 7.3 2.4 8.8 0.2 2.8 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Kunitz_BPTI PF00014.23 CBY33283.1 - 8.8e-23 80.3 17.0 8.6e-16 57.9 0.4 2.2 2 0 0 2 2 2 2 Kunitz/Bovine pancreatic trypsin inhibitor domain Collagen PF01391.18 CBY33284.1 - 0.0038 16.9 9.5 0.029 14.1 9.5 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF1816 PF08846.10 CBY33285.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF3719 PF12516.8 CBY33286.1 - 0.0023 17.6 0.1 0.0068 16.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) Acyl-CoA_dh_1 PF00441.24 CBY33289.1 - 3.1e-32 111.8 2.7 4.4e-32 111.4 2.7 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY33289.1 - 4.7e-09 36.6 0.4 6.9e-09 36.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY33289.1 - 0.0019 18.4 0.0 0.0044 17.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain APH PF01636.23 CBY33290.1 - 2.3e-43 148.9 0.0 3.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HAD_2 PF13419.6 CBY33290.1 - 1.3e-18 67.7 0.7 5.7e-18 65.6 0.5 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY33290.1 - 7.5e-09 36.2 0.2 2.9e-07 31.0 0.1 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY33290.1 - 2.3e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.20 CBY33290.1 - 0.00019 21.1 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY33290.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase_6 PF13344.6 CBY33290.1 - 0.0068 16.5 0.1 0.044 13.9 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase RIO1 PF01163.22 CBY33290.1 - 0.013 15.1 0.0 0.28 10.8 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Acid_PPase PF12689.7 CBY33290.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 Acid Phosphatase Fructosamin_kin PF03881.14 CBY33290.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase MFS_5 PF05631.14 CBY33291.1 - 1.9e-39 135.6 3.1 2.1e-39 135.5 3.1 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY33291.1 - 7e-09 35.1 8.2 2.4e-08 33.3 9.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY33291.1 - 0.002 17.1 1.5 0.0023 16.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY33292.1 - 0.00042 19.3 10.7 0.00051 19.1 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Thyroglobulin_1 PF00086.18 CBY33294.1 - 3.7e-05 23.3 0.1 6.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat THDPS_N_2 PF14805.6 CBY33295.1 - 0.07 13.4 0.4 17 5.7 0.1 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal IL1_propep PF02394.16 CBY33295.1 - 3 8.8 10.6 0.37 11.7 0.6 3.3 2 1 1 3 3 3 0 Interleukin-1 propeptide Trypsin PF00089.26 CBY33296.1 - 3.7e-25 89.0 0.3 3.7e-25 89.0 0.3 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY33296.1 - 0.00056 20.8 0.1 0.00056 20.8 0.1 2.2 3 0 0 3 3 3 1 Trypsin-like peptidase domain RVT_1 PF00078.27 CBY33297.1 - 2.4e-23 82.8 0.0 5.1e-22 78.5 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.14 CBY33299.1 - 0.00082 19.1 2.5 0.0011 18.7 0.3 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4080 PF13311.6 CBY33299.1 - 0.049 13.8 1.8 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Cofilin_ADF PF00241.20 CBY33304.1 - 2.7e-22 78.8 0.5 3.9e-22 78.3 0.5 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Peptidase_C98 PF15499.6 CBY33304.1 - 0.0023 17.5 0.1 0.43 10.0 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Mfa1 PF17445.2 CBY33305.1 - 0.03 14.3 2.3 0.03 14.3 2.3 2.7 4 0 0 4 4 4 0 Mating factor A1 dCMP_cyt_deam_1 PF00383.23 CBY33306.1 - 3.9e-13 49.1 0.2 1.1e-12 47.6 0.2 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY33306.1 - 3.2e-07 30.6 1.3 1.1e-06 28.8 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CBY33306.1 - 0.02 14.5 1.7 1.1 8.9 0.2 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhaC_N PF07167.13 CBY33306.1 - 0.098 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus O-FucT PF10250.9 CBY33307.1 - 1.2e-05 25.2 1.2 4.3e-05 23.4 1.2 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Homeodomain PF00046.29 CBY33309.1 - 2.3e-13 49.7 0.5 5.2e-13 48.6 0.5 1.6 1 0 0 1 1 1 1 Homeodomain Pou PF00157.17 CBY33309.1 - 3.2e-07 30.2 0.7 1.2e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain DUF1951 PF09188.10 CBY33309.1 - 0.045 13.7 0.1 0.081 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) dCMP_cyt_deam_1 PF00383.23 CBY33310.1 - 3.9e-13 49.1 0.2 1.1e-12 47.6 0.2 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY33310.1 - 3.2e-07 30.6 1.3 1.1e-06 28.8 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CBY33310.1 - 0.02 14.5 1.7 1.1 8.9 0.2 2.3 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases PhaC_N PF07167.13 CBY33310.1 - 0.098 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus O-FucT PF10250.9 CBY33311.1 - 1.6e-05 24.8 0.4 5.3e-05 23.1 0.4 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Endonuclease_NS PF01223.23 CBY33313.1 - 9.8e-25 87.7 4.9 3.7e-24 85.8 4.9 1.7 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBY33313.1 - 0.011 15.8 0.2 0.027 14.6 0.2 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DUF4762 PF15959.5 CBY33313.1 - 0.028 14.4 0.2 0.065 13.2 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4762) Ceramidase PF05875.12 CBY33313.1 - 0.041 13.3 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Ceramidase Pox_F15 PF04596.12 CBY33313.1 - 0.045 13.5 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 NAAA-beta PF15508.6 CBY33315.1 - 0.12 12.7 0.3 0.55 10.6 0.1 2.0 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pkinase PF00069.25 CBY33317.1 - 2.1e-47 161.7 0.0 3.5e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33317.1 - 8.2e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY33317.1 - 6.1e-06 25.7 0.5 0.00011 21.7 0.0 2.6 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY33317.1 - 6.3e-05 22.6 0.8 8.2e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 RIO1 family SfLAP PF11139.8 CBY33318.1 - 0.086 12.3 0.3 0.13 11.7 0.3 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein PHC2_SAM_assoc PF16616.5 CBY33318.1 - 0.56 11.0 3.4 2.3 9.1 0.3 2.2 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF4731 PF15875.5 CBY33318.1 - 0.71 10.1 2.2 11 6.3 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) Trypsin PF00089.26 CBY33320.1 - 2.4e-49 168.1 6.6 3.5e-49 167.6 6.6 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY33320.1 - 7e-05 23.8 0.0 0.00017 22.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain CUB PF00431.20 CBY33321.1 - 6.8e-11 42.5 0.1 6e-10 39.5 0.0 2.3 1 1 1 2 2 2 1 CUB domain Phospholip_B PF04916.13 CBY33323.1 - 5.8e-158 526.8 1.1 7.3e-158 526.4 1.1 1.0 1 0 0 1 1 1 1 Phospholipase B PDZ PF00595.24 CBY33324.1 - 3.2e-12 46.6 0.4 7.1e-12 45.5 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_5 PF17817.1 CBY33324.1 - 5.1e-11 42.7 0.0 2.4e-10 40.5 0.0 2.2 1 0 0 1 1 1 1 PDZ domain SAM_1 PF00536.30 CBY33324.1 - 6.5e-06 26.5 0.3 1.3e-05 25.6 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY33324.1 - 1.8e-05 24.8 0.3 3.6e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDZ_6 PF17820.1 CBY33324.1 - 1.8e-05 24.5 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY33324.1 - 0.00029 21.1 0.1 0.00066 20.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF724 PF05266.14 CBY33324.1 - 0.0026 17.6 0.7 0.0026 17.6 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF724) JIP_LZII PF16471.5 CBY33324.1 - 0.022 14.9 3.7 0.022 14.9 3.7 2.4 3 0 0 3 3 2 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 CBY33324.1 - 0.032 14.7 3.7 0.032 14.7 3.7 3.1 4 0 0 4 4 3 0 Cell division protein ZapB Use1 PF09753.9 CBY33324.1 - 0.24 11.1 10.1 0.48 10.1 10.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 KCT2 PF17818.1 CBY33324.1 - 0.27 11.3 2.5 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Keratinocyte-associated gene product DUF87 PF01935.17 CBY33324.1 - 0.64 10.1 5.5 1.6 8.8 5.5 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Atg14 PF10186.9 CBY33324.1 - 3.3 6.7 11.5 6.5 5.7 11.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBY33324.1 - 4.6 6.5 10.1 0.25 10.7 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FUSC PF04632.12 CBY33324.1 - 6.2 5.2 4.5 10 4.5 4.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 CBY33324.1 - 6.5 7.5 10.4 1.6 9.5 1.8 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Virulence_fact PF13769.6 CBY33324.1 - 7.2 6.9 6.7 10 6.4 0.3 2.8 2 0 0 2 2 2 0 Virulence factor Med18 PF09637.10 CBY33325.1 - 5.3e-26 92.0 0.0 7.9e-19 68.5 0.0 2.1 1 1 1 2 2 2 2 Med18 protein Cyclin_N PF00134.23 CBY33326.1 - 2.7e-33 114.4 3.8 6.3e-33 113.2 3.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY33326.1 - 1.5e-21 76.7 1.1 1.5e-21 76.7 1.1 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Hexokinase_2 PF03727.16 CBY33327.1 - 0.2 11.1 0.3 0.58 9.5 0.1 1.8 2 1 0 2 2 2 0 Hexokinase TPR_8 PF13181.6 CBY33328.1 - 2.6 8.5 5.0 16 6.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 CBY33329.1 - 0.00025 21.1 0.1 0.00027 21.0 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain RT_RNaseH_2 PF17919.1 CBY33329.1 - 0.018 15.1 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase MFS_1 PF07690.16 CBY33330.1 - 1.5e-31 109.6 28.3 2e-29 102.6 23.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sushi PF00084.20 CBY33331.1 - 0.015 15.9 42.4 0.037 14.6 0.6 8.2 7 0 0 7 7 7 0 Sushi repeat (SCR repeat) Peptidase_C24 PF03510.14 CBY33331.1 - 0.029 14.9 0.1 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family Mitofilin PF09731.9 CBY33332.1 - 0.13 11.0 17.3 0.16 10.8 17.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mpp10 PF04006.12 CBY33332.1 - 0.25 9.8 19.9 0.32 9.4 19.9 1.1 1 0 0 1 1 1 0 Mpp10 protein API5 PF05918.11 CBY33332.1 - 0.3 9.9 11.7 0.37 9.5 11.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RR_TM4-6 PF06459.12 CBY33332.1 - 3.1 7.6 14.5 4.2 7.1 14.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CBY33332.1 - 3.8 6.3 21.6 4.8 6.0 21.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Voltage_CLC PF00654.20 CBY33333.1 - 1.4e-56 192.3 8.5 1.4e-56 192.3 8.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Ank_2 PF12796.7 CBY33335.1 - 9.7e-55 183.1 2.8 4.9e-12 46.3 0.2 5.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 CBY33335.1 - 2e-47 162.1 0.0 2.6e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Ank_5 PF13857.6 CBY33335.1 - 9.9e-44 146.8 5.5 3.9e-11 43.0 0.0 8.7 3 3 6 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY33335.1 - 3.2e-38 129.6 4.6 1.2e-08 35.3 0.0 8.5 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33335.1 - 1.4e-33 111.1 1.5 0.0059 17.0 0.0 10.7 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 CBY33335.1 - 3.1e-31 106.4 2.7 0.0017 18.7 0.1 10.5 10 0 0 10 10 10 8 Ankyrin repeat DHR-2 PF06920.13 CBY33336.1 - 2.3e-60 204.7 1.1 2.3e-60 204.7 1.1 2.6 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 CBY33336.1 - 2.4e-40 138.4 0.1 4.9e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Lipocalin PF00061.23 CBY33337.1 - 0.0082 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CBY33337.1 - 0.049 13.6 0.1 0.066 13.2 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Aa_trans PF01490.18 CBY33338.1 - 8.8e-74 248.6 34.1 5e-40 137.5 12.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Pkinase PF00069.25 CBY33340.1 - 3.2e-58 197.2 0.0 3.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33340.1 - 3.4e-21 75.7 0.0 4.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33340.1 - 4.1e-07 29.6 0.0 5.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY33340.1 - 1.6e-06 27.6 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY33340.1 - 0.035 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CBY33340.1 - 0.056 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY33340.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Na_H_Exchanger PF00999.21 CBY33342.1 - 3.1e-60 204.0 24.5 3.8e-60 203.7 24.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 CBY33342.1 - 0.079 13.2 8.6 0.17 12.2 8.6 1.5 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Galactosyl_T PF01762.21 CBY33343.1 - 8.3e-35 120.4 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY33343.1 - 6.7 7.3 10.4 6.6 7.3 5.7 2.5 2 0 0 2 2 2 0 Chitin recognition protein Trypsin PF00089.26 CBY33344.1 - 2.7e-51 174.5 1.3 3.5e-51 174.1 1.3 1.1 1 0 0 1 1 1 1 Trypsin Zona_pellucida PF00100.23 CBY33344.1 - 6.2e-21 75.3 0.0 1e-20 74.7 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain DUF1986 PF09342.11 CBY33344.1 - 0.0014 19.0 0.0 0.0023 18.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trefoil PF00088.18 CBY33345.1 - 0.012 15.4 4.7 0.022 14.6 4.7 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain CRT10 PF08728.10 CBY33346.1 - 3.2 5.8 14.7 3.9 5.5 14.7 1.2 1 0 0 1 1 1 0 CRT10 ALMT PF11744.8 CBY33346.1 - 7.5 5.3 16.0 9 5.0 16.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C2H2 PF00096.26 CBY33348.1 - 1.9e-19 68.9 23.0 1e-06 28.8 0.6 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY33348.1 - 6.4e-12 45.3 19.4 1.5e-07 31.5 0.2 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY33348.1 - 1.2e-08 35.1 24.5 0.012 16.3 0.4 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY33348.1 - 0.00036 20.7 8.2 0.99 9.8 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY33348.1 - 0.015 15.6 7.1 8.7 6.7 0.8 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CBY33348.1 - 0.019 14.7 10.6 1.7 8.5 1.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBY33348.1 - 0.028 14.6 6.5 3.7 7.7 0.1 3.3 1 1 2 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 CBY33348.1 - 0.055 13.4 1.0 0.4 10.6 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 CBY33348.1 - 0.66 10.0 4.8 9.5 6.3 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CBY33348.1 - 1.7 9.2 10.4 2.9 8.4 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 CBY33348.1 - 2.2 8.6 7.3 1.4 9.2 0.8 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Sad1_UNC PF07738.13 CBY33349.1 - 0.0027 17.7 1.2 0.011 15.7 0.0 2.3 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal AIP3 PF03915.13 CBY33349.1 - 0.049 12.7 11.5 0.064 12.3 11.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Borrelia_REV PF03978.13 CBY33349.1 - 3.3 7.6 12.3 0.14 12.1 3.2 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein DUF3573 PF12097.8 CBY33349.1 - 3.9 6.2 14.9 0.77 8.5 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Nucleoside_tran PF01733.18 CBY33349.1 - 7.6 5.8 5.1 2.2 7.6 1.8 1.7 2 0 0 2 2 2 0 Nucleoside transporter Mitoc_L55 PF09776.9 CBY33351.1 - 6.2e-14 51.7 0.2 7.6e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L55 DUF4296 PF14129.6 CBY33352.1 - 0.099 13.3 0.6 0.22 12.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) DUF4685 PF15737.5 CBY33352.1 - 0.25 11.8 3.7 1.5 9.3 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4685) YliH PF10799.8 CBY33353.1 - 0.17 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Ribosomal_60s PF00428.19 CBY33355.1 - 8.5e-23 80.8 9.7 1e-22 80.5 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF108 PF01958.18 CBY33355.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF108 Ribosomal_L5e PF17144.4 CBY33356.1 - 6.9e-80 266.8 0.4 6.9e-80 266.8 0.4 2.1 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBY33356.1 - 3.9e-35 120.7 5.8 3.9e-35 120.7 5.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thg1C PF14413.6 CBY33356.1 - 0.024 14.8 2.3 0.96 9.6 1.5 2.3 2 0 0 2 2 2 0 Thg1 C terminal domain MecA_N PF05223.11 CBY33356.1 - 0.1 12.9 0.6 0.31 11.3 0.7 1.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain Ribosomal_S6e PF01092.19 CBY33358.1 - 9.9e-57 190.3 0.1 9.9e-57 190.3 0.1 2.1 2 1 0 2 2 2 1 Ribosomal protein S6e DUF755 PF05501.11 CBY33358.1 - 0.0037 17.5 13.2 0.0065 16.7 13.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF755) ATPase-cat_bd PF12156.8 CBY33358.1 - 0.09 13.5 1.0 0.23 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase DUF2992 PF11208.8 CBY33358.1 - 1.3 9.2 17.4 0.42 10.9 14.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Protocadherin PF08374.11 CBY33358.1 - 1.4 8.8 8.1 2.2 8.2 8.1 1.4 1 0 0 1 1 1 0 Protocadherin Urm1 PF09138.11 CBY33359.1 - 5.1e-24 84.5 0.0 5.6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CBY33359.1 - 0.0026 18.4 0.0 0.0034 18.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family DUF2585 PF10755.9 CBY33361.1 - 0.2 11.4 2.3 0.36 10.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) SID-1_RNA_chan PF13965.6 CBY33361.1 - 2.7 6.3 10.1 3.5 5.9 10.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GGACT PF06094.12 CBY33362.1 - 3.5e-17 63.1 0.0 4.5e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CBY33362.1 - 0.0056 17.0 0.0 0.0085 16.5 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Adeno_E3_15_3 PF03307.14 CBY33362.1 - 0.02 14.8 0.1 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region Adaptin_N PF01602.20 CBY33363.1 - 0.00073 18.2 0.3 0.0014 17.3 0.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region CRM1_repeat PF18777.1 CBY33363.1 - 0.079 12.5 0.2 0.26 10.9 0.2 1.9 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat LIM PF00412.22 CBY33364.1 - 7.1e-42 141.5 72.2 3e-12 46.6 6.0 5.4 5 1 0 5 5 5 5 LIM domain Lipoprotein_15 PF03640.15 CBY33364.1 - 0.13 11.9 0.2 0.29 10.7 0.2 1.6 1 0 0 1 1 1 0 Secreted repeat of unknown function Glyco_transf_10 PF00852.19 CBY33365.1 - 2.1e-49 167.7 0.0 4.3e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY33365.1 - 4.3e-15 56.1 0.1 1e-14 54.9 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Elongin_A PF06881.11 CBY33365.1 - 1.9 9.0 7.9 0.38 11.3 3.8 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A EF-hand_1 PF00036.32 CBY33366.1 - 4.9e-13 47.6 10.9 1.2e-07 30.8 0.6 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CBY33366.1 - 6.3e-12 45.8 4.4 2.5e-11 43.8 3.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY33366.1 - 5.3e-11 41.5 7.6 9.9e-08 31.3 1.0 2.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY33366.1 - 1.3e-08 33.9 3.4 3.6e-06 26.2 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY33366.1 - 1.8e-06 27.7 10.0 0.0013 18.5 2.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY33366.1 - 2.7e-05 24.4 0.4 3.3e-05 24.2 0.4 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY33366.1 - 0.00014 22.1 3.4 0.00037 20.8 0.4 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBY33366.1 - 0.0015 18.4 3.7 0.018 14.9 0.6 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Peptidase_C1 PF00112.23 CBY33367.1 - 4.5e-79 265.5 4.4 6.7e-79 265.0 4.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY33367.1 - 2.4e-10 40.7 2.1 4.1e-10 39.9 2.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY33367.1 - 0.0015 17.4 1.3 0.15 10.8 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Phage_TAC_4 PF08748.11 CBY33368.1 - 0.0071 16.7 0.4 0.026 14.8 0.4 1.9 1 0 0 1 1 1 1 Phage tail assembly chaperone EF-hand_6 PF13405.6 CBY33369.1 - 9.8e-12 43.8 0.3 1.1e-06 28.1 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY33369.1 - 8.5e-11 40.6 2.5 7.2e-06 25.2 0.4 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY33369.1 - 1.5e-09 38.2 0.1 0.00035 21.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY33369.1 - 1.1e-06 28.3 2.7 0.029 14.2 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY33369.1 - 1.2e-05 24.6 2.0 4.1e-05 22.9 1.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 CBY33369.1 - 0.009 15.9 0.2 0.061 13.3 0.0 2.1 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CBY33370.1 - 2.5e-58 197.5 0.0 3.3e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33370.1 - 2.2e-21 76.3 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33370.1 - 3.9e-06 26.4 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY33370.1 - 5.9e-05 22.5 0.0 9.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY33370.1 - 0.014 14.2 0.0 0.029 13.1 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Ank PF00023.30 CBY33372.1 - 1.1e-06 28.7 0.1 1.4e-05 25.3 0.2 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBY33372.1 - 1.6e-06 28.6 0.0 1.2e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY33372.1 - 6.1e-05 23.1 0.1 0.00036 20.8 0.0 2.4 2 0 0 2 2 1 1 Ankyrin repeat Ank_4 PF13637.6 CBY33372.1 - 0.00024 21.6 0.0 0.39 11.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY33372.1 - 0.00038 20.7 0.1 0.021 15.2 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TPR_12 PF13424.6 CBY33372.1 - 0.0068 16.7 1.2 0.021 15.1 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY33372.1 - 0.084 13.1 0.0 0.37 11.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.6 CBY33372.1 - 0.097 12.5 24.6 1.1 9.1 0.2 6.2 3 2 2 6 6 6 0 Leucine rich repeat LRR_4 PF12799.7 CBY33372.1 - 0.36 11.3 24.0 1.5 9.3 0.2 5.4 2 2 4 6 6 6 0 Leucine Rich repeats (2 copies) CelTOS PF18659.1 CBY33372.1 - 2.4 8.6 5.2 3 8.3 0.4 2.5 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites LTXXQ PF07813.12 CBY33372.1 - 2.8 8.7 5.2 55 4.5 0.0 3.0 2 0 0 2 2 2 0 LTXXQ motif family protein Molybdopterin PF00384.22 CBY33373.1 - 2.7e-61 207.8 0.0 7.3e-60 203.1 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CBY33373.1 - 1.5e-20 73.0 0.5 3e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CBY33373.1 - 5.7e-17 61.0 0.3 5.7e-17 61.0 0.3 2.1 3 0 0 3 3 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CBY33373.1 - 6e-10 38.9 0.6 6e-10 38.9 0.6 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 CBY33373.1 - 4.4e-08 33.7 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer4 PF00037.27 CBY33373.1 - 0.014 15.2 5.1 0.75 9.7 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lyx_isomer PF07385.12 CBY33373.1 - 0.031 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase Fer4_16 PF13484.6 CBY33373.1 - 0.05 14.5 3.0 18 6.4 2.6 3.0 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY33373.1 - 0.36 11.0 5.4 1.9 8.7 5.4 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBY33373.1 - 0.41 11.3 6.1 0.54 10.9 3.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CBY33373.1 - 5.4 7.5 8.5 21 5.7 8.5 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBY33373.1 - 7.4 7.3 10.0 1 10.0 3.1 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY33373.1 - 9.3 6.9 8.9 0.84 10.2 3.3 2.2 2 0 0 2 2 1 0 4Fe-4S dicluster domain Lipocalin_2 PF08212.12 CBY33375.1 - 2e-14 53.7 0.0 2.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY33375.1 - 1.2e-09 38.5 0.0 1.7e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 CBY33375.1 - 0.0014 18.6 0.4 0.0029 17.5 0.3 1.6 1 1 0 1 1 1 1 Triabin GST_N PF02798.20 CBY33376.1 - 8.4e-07 29.2 0.0 2.3e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY33376.1 - 9.8e-07 28.9 0.0 1.7e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY33376.1 - 0.014 15.6 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Neur_chan_memb PF02932.16 CBY33377.1 - 1.5e-49 169.2 10.4 1.2e-47 163.0 10.4 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY33377.1 - 2.7e-45 154.5 0.0 3.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Ion_trans PF00520.31 CBY33378.1 - 2e-10 40.3 0.3 3.2e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Ion transport protein RVT_1 PF00078.27 CBY33378.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DHHC PF01529.20 CBY33378.1 - 0.26 11.4 3.4 0.21 11.7 0.8 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase RYDR_ITPR PF01365.21 CBY33379.1 - 1.5e-113 377.2 23.8 1.3e-66 223.9 0.3 4.1 3 0 0 3 3 3 2 RIH domain RyR PF02026.16 CBY33379.1 - 4.9e-105 343.9 2.1 3.7e-25 87.9 0.0 5.0 4 0 0 4 4 4 4 RyR domain SPRY PF00622.28 CBY33379.1 - 2.6e-57 192.1 2.0 2.1e-22 79.5 0.0 3.7 3 0 0 3 3 3 3 SPRY domain RR_TM4-6 PF06459.12 CBY33379.1 - 2.1e-36 126.2 4.0 2.1e-36 126.2 4.0 2.7 4 0 0 4 4 4 1 Ryanodine Receptor TM 4-6 Ins145_P3_rec PF08709.11 CBY33379.1 - 2.2e-36 125.1 4.5 2.8e-35 121.5 0.1 3.7 3 1 0 4 4 4 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 CBY33379.1 - 1.8e-34 119.2 0.1 3e-32 112.0 0.0 3.1 2 1 1 3 3 3 1 MIR domain RIH_assoc PF08454.11 CBY33379.1 - 4.5e-31 106.7 0.1 4.5e-31 106.7 0.1 4.1 4 0 0 4 4 4 1 RyR and IP3R Homology associated EF-hand_7 PF13499.6 CBY33379.1 - 5.3e-06 26.8 1.1 2.7e-05 24.5 1.1 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY33379.1 - 0.023 14.5 0.2 0.51 10.2 0.0 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CBY33379.1 - 0.075 13.0 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain PRA-PH PF01503.17 CBY33379.1 - 0.092 13.2 0.3 6.9 7.2 0.1 3.0 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase TSP_1 PF00090.19 CBY33380.1 - 2.1e-42 143.1 204.7 2.1e-08 34.3 8.4 14.0 14 0 0 14 14 14 11 Thrombospondin type 1 domain ShK PF01549.24 CBY33380.1 - 6.4e-11 42.6 39.2 6e-07 29.9 5.5 14.7 15 0 0 15 15 15 6 ShK domain-like F5_F8_type_C PF00754.25 CBY33380.1 - 0.00036 20.6 0.2 0.0083 16.2 0.2 2.7 1 1 0 1 1 1 1 F5/8 type C domain DUF4094 PF13334.6 CBY33381.1 - 1.9 9.0 5.5 1.9 8.9 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) HIP1_clath_bdg PF16515.5 CBY33381.1 - 2.1 9.0 8.6 2.3 8.9 1.7 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GH97_N PF14508.6 CBY33382.1 - 0.035 13.6 0.3 0.039 13.5 0.3 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Activator_LAG-3 PF11498.8 CBY33382.1 - 0.057 12.4 15.0 0.061 12.3 15.0 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Sulfotransfer_2 PF03567.14 CBY33383.1 - 1.2e-07 31.9 3.0 1.6e-07 31.5 3.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY33383.1 - 0.024 15.0 0.2 0.056 13.8 0.2 1.5 1 1 0 1 1 1 0 Sulfotransferase family DUF1442 PF07279.11 CBY33384.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Pkinase PF00069.25 CBY33385.1 - 6.9e-12 45.3 3.3 2.6e-11 43.4 0.7 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33385.1 - 9.3e-07 28.4 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY33385.1 - 0.064 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 CBY33386.1 - 8.4e-74 248.2 0.0 1.3e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33386.1 - 2.5e-39 135.1 0.1 5.4e-39 134.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBY33386.1 - 1.9e-06 28.0 0.1 0.0014 18.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBY33386.1 - 3.4e-05 23.3 0.4 6.4e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY33386.1 - 5.3e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY33386.1 - 0.0018 17.3 0.3 0.0041 16.1 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY33386.1 - 0.0039 16.8 0.1 0.013 15.1 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase MRP-S23 PF10484.9 CBY33387.1 - 2.7e-14 53.5 1.3 2.7e-14 53.5 1.3 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 zf-MIZ PF02891.20 CBY33388.1 - 0.00018 21.2 0.2 0.00038 20.1 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Ank_3 PF13606.6 CBY33388.1 - 0.012 16.0 0.0 0.044 14.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat TMEM132D_N PF15705.5 CBY33388.1 - 0.073 12.9 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term DUF3767 PF12597.8 CBY33388.1 - 0.15 11.9 1.7 0.41 10.5 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) IMD PF08397.11 CBY33388.1 - 0.23 10.8 11.7 0.61 9.4 11.7 1.7 1 0 0 1 1 1 0 IRSp53/MIM homology domain TEX13 PF15186.6 CBY33388.1 - 0.55 9.9 15.4 0.049 13.3 8.0 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family zf-Nse PF11789.8 CBY33388.1 - 0.67 9.8 3.4 0.59 10.0 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF4349 PF14257.6 CBY33388.1 - 1.5 8.2 6.2 1.7 8.0 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 CBY33388.1 - 1.7 7.9 9.5 2.7 7.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EMC3_TMCO1 PF01956.16 CBY33388.1 - 3.1 7.5 8.2 6.5 6.4 8.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TPR_19 PF14559.6 CBY33389.1 - 1.6e-16 60.5 5.2 0.00055 20.4 0.0 5.8 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY33389.1 - 2.4e-12 46.0 21.8 0.14 12.4 0.1 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY33389.1 - 3.5e-12 46.4 17.6 0.012 15.9 0.2 6.1 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY33389.1 - 8.8e-08 32.7 1.0 0.81 10.4 0.0 5.8 6 1 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY33389.1 - 4.3e-07 30.2 0.8 2.4 9.2 0.0 6.4 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY33389.1 - 7.6e-07 29.1 2.2 0.22 12.0 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY33389.1 - 3.9e-06 27.0 8.0 11 6.4 0.0 6.8 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY33389.1 - 8.1e-06 25.5 5.0 0.31 11.2 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 CBY33389.1 - 4e-05 23.6 1.2 10 6.6 0.0 5.2 5 0 0 5 5 4 0 PPR repeat HrpB1_HrpK PF09613.10 CBY33389.1 - 0.00016 21.3 0.0 1.7 8.3 0.0 4.6 2 2 3 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) PPR_2 PF13041.6 CBY33389.1 - 0.0014 18.7 0.9 16 5.8 0.0 4.8 4 1 1 5 5 4 0 PPR repeat family Coatomer_E PF04733.14 CBY33389.1 - 0.0023 17.4 0.3 0.46 9.8 0.0 3.2 2 1 0 3 3 3 1 Coatomer epsilon subunit TPR_6 PF13174.6 CBY33389.1 - 0.0023 18.4 18.0 2.8 8.8 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat RPN7 PF10602.9 CBY33389.1 - 0.0025 17.5 0.1 0.078 12.7 0.0 2.7 2 1 0 2 2 2 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 CBY33389.1 - 0.005 16.7 13.2 0.45 10.5 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY33389.1 - 0.0083 15.8 0.6 0.6 9.8 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_4 PF07721.14 CBY33389.1 - 0.0086 16.6 0.0 8.9 7.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY33389.1 - 0.011 15.5 16.4 1 9.3 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY33389.1 - 0.08 13.0 7.3 0.32 11.1 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 CBY33389.1 - 0.27 11.5 11.8 13 6.3 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Dynein_light PF01221.18 CBY33390.1 - 1.2e-20 73.5 0.1 1.7e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Nkap_C PF06047.11 CBY33391.1 - 1.8e-37 127.6 5.8 1.8e-37 127.6 5.8 2.9 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain RNA_polI_A34 PF08208.11 CBY33391.1 - 1.2 9.1 30.5 0.56 10.3 27.2 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 CBY33391.1 - 2 8.0 38.7 0.25 10.9 31.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein THOC2_N PF16134.5 CBY33391.1 - 4.2 5.9 15.2 7 5.1 15.2 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus LicD PF04991.13 CBY33391.1 - 8.6 6.4 17.2 2.2 8.3 11.3 2.1 2 0 0 2 2 2 0 LicD family DUF913 PF06025.12 CBY33391.1 - 9.3 5.1 10.1 15 4.4 10.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tubulin PF00091.25 CBY33392.1 - 5.5e-67 225.8 0.0 7.2e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY33392.1 - 2.2e-51 173.3 0.0 3.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY33392.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain CUB PF00431.20 CBY33393.1 - 4.6e-10 39.8 1.0 9.6e-10 38.8 1.0 1.5 1 0 0 1 1 1 1 CUB domain F-box PF00646.33 CBY33394.1 - 1.2e-05 25.0 0.6 0.00021 21.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY33394.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like MRP-L28 PF09812.9 CBY33394.1 - 0.0062 16.7 0.4 0.012 15.8 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Na_trans_assoc PF06512.13 CBY33398.1 - 5.3 7.3 8.3 8.7 6.6 8.3 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated eIF_4EBP PF05456.11 CBY33399.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GOLD_2 PF13897.6 CBY33399.1 - 0.82 10.2 4.5 2.8 8.4 0.4 2.5 2 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking UQ_con PF00179.26 CBY33400.1 - 3.7e-45 153.0 0.1 4.9e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY33400.1 - 0.00075 19.2 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY33400.1 - 0.011 16.0 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 0 RWD domain Lon_C PF05362.13 CBY33401.1 - 1.9e-65 220.3 0.1 4.5e-65 219.0 0.1 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CBY33401.1 - 1.9e-22 80.1 0.0 1.5e-21 77.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CBY33401.1 - 5.4e-21 75.4 0.9 1.1e-20 74.4 0.9 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain RuvB_N PF05496.12 CBY33401.1 - 1.7e-07 31.1 0.0 4.1e-06 26.6 0.0 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY33401.1 - 1.8e-06 28.2 0.1 1.5e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY33401.1 - 6.7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CBY33401.1 - 7.2e-06 25.1 0.0 1.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CBY33401.1 - 1.3e-05 25.7 0.1 6.9e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY33401.1 - 5.1e-05 23.6 1.4 0.0042 17.4 0.1 3.7 2 2 1 3 3 3 1 AAA domain ChlI PF13541.6 CBY33401.1 - 0.00024 21.0 0.1 0.00077 19.3 0.1 2.0 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_11 PF13086.6 CBY33401.1 - 0.0028 17.5 2.3 0.055 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBY33401.1 - 0.0037 16.5 0.0 0.0037 16.5 0.0 3.0 4 0 0 4 4 4 1 TIP49 P-loop domain RNA_helicase PF00910.22 CBY33401.1 - 0.0054 17.1 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CBY33401.1 - 0.0061 16.7 0.6 0.022 14.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBY33401.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 CBY33401.1 - 0.01 16.4 0.4 0.044 14.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBY33401.1 - 0.011 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CBY33401.1 - 0.012 14.9 1.0 0.033 13.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 CBY33401.1 - 0.014 15.1 2.7 0.18 11.5 0.0 3.2 2 1 1 3 3 3 0 Cytidylate kinase IstB_IS21 PF01695.17 CBY33401.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Torsin PF06309.11 CBY33401.1 - 0.019 15.0 0.0 0.068 13.3 0.0 1.9 1 0 0 1 1 1 0 Torsin NACHT PF05729.12 CBY33401.1 - 0.027 14.4 0.0 0.21 11.5 0.0 2.4 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CBY33401.1 - 0.028 14.3 0.1 2.6 7.9 0.0 3.1 1 1 1 2 2 2 0 NTPase TsaE PF02367.17 CBY33401.1 - 0.03 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY33401.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Nucleoporin_C PF03177.14 CBY33401.1 - 0.031 13.0 2.7 0.054 12.2 2.7 1.3 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal AAA_23 PF13476.6 CBY33401.1 - 0.034 14.6 4.0 0.21 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBY33401.1 - 0.044 13.1 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 CBY33401.1 - 0.059 12.3 0.6 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Parvo_NS1 PF01057.17 CBY33401.1 - 0.063 12.4 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CBY33401.1 - 0.07 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBY33401.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBY33401.1 - 0.12 12.7 0.0 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY33401.1 - 2.3 8.7 5.8 0.8 10.2 0.1 2.9 2 1 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 CBY33401.1 - 5 7.6 6.9 1.2 9.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain Glyco_transf_7C PF02709.14 CBY33404.1 - 5.8e-28 96.4 0.3 5.8e-28 96.4 0.3 1.6 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CBY33404.1 - 2.5e-21 75.7 0.8 3.6e-21 75.2 0.8 1.2 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Prominin PF05478.11 CBY33405.1 - 0.097 10.6 2.6 0.13 10.2 2.6 1.1 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 CBY33405.1 - 0.12 10.3 3.9 0.14 10.0 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.17 CBY33405.1 - 0.14 12.2 7.9 0.18 11.9 6.9 1.5 1 1 1 2 2 2 0 Helicase HerA, central domain ACR_tran PF00873.19 CBY33405.1 - 0.22 9.1 1.5 0.28 8.8 1.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MapZ_EC1 PF18041.1 CBY33405.1 - 1.4 9.1 8.7 2.4 8.4 5.9 2.2 1 1 1 2 2 2 0 MapZ extracellular domain 1 Snf7 PF03357.21 CBY33405.1 - 1.5 8.4 17.5 0.74 9.4 7.6 2.8 2 1 1 3 3 3 0 Snf7 ABC_tran_Xtn PF12848.7 CBY33405.1 - 4.1 7.5 11.7 3.6 7.7 5.1 2.9 1 1 2 3 3 3 0 ABC transporter DEAD PF00270.29 CBY33407.1 - 8.7e-47 159.1 0.0 2.1e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY33407.1 - 6.7e-27 94.0 0.0 2.6e-26 92.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LSM PF01423.22 CBY33408.1 - 2.4e-21 75.2 0.2 2.9e-21 74.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF3585 PF12130.8 CBY33409.1 - 2.6e-20 72.9 21.2 2.6e-20 72.9 21.2 2.4 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain CH PF00307.31 CBY33409.1 - 9.3e-09 35.4 0.2 2.6e-08 34.0 0.2 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Pyr_redox_2 PF07992.14 CBY33409.1 - 9.1e-05 21.8 0.7 0.00018 20.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY33409.1 - 0.00018 20.9 0.6 0.00073 18.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 CBY33409.1 - 0.0013 19.2 0.0 0.0055 17.1 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 CBY33409.1 - 0.0019 17.5 0.0 0.0056 16.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY33409.1 - 0.0029 16.8 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CBY33409.1 - 0.0036 16.1 0.0 0.0036 16.1 0.0 2.8 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox PF00070.27 CBY33409.1 - 0.0072 16.9 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CBY33409.1 - 0.011 15.1 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CBY33409.1 - 0.57 10.0 6.8 3.2 7.6 0.0 3.4 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C4 PF00105.18 CBY33410.1 - 1.3e-16 60.8 9.9 2.1e-16 60.1 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) BaffR-Tall_bind PF09256.10 CBY33410.1 - 1.7 8.5 4.3 3.4 7.5 4.3 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Glyco_transf_24 PF18404.1 CBY33411.1 - 2e-127 424.2 5.6 6.6e-127 422.5 3.7 2.4 2 1 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CBY33411.1 - 2.2e-40 139.2 1.1 6.6e-36 124.6 0.1 3.5 2 1 0 3 3 3 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CBY33411.1 - 2.8e-33 114.3 0.0 6.3e-33 113.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 CBY33411.1 - 1.2e-22 80.3 0.0 1.1e-21 77.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CBY33411.1 - 2.6e-06 27.5 0.9 0.0062 16.5 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CBY33411.1 - 4.4e-06 26.4 1.3 1.6e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Thioredoxin_12 PF18400.1 CBY33411.1 - 5e-06 26.5 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain GST_N PF02798.20 CBY33412.1 - 2.7e-29 101.3 0.1 8.1e-14 51.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY33412.1 - 2.9e-27 94.9 0.1 3.2e-13 49.9 0.0 2.7 3 0 0 3 3 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY33412.1 - 3.8e-21 75.1 0.0 1.7e-09 37.8 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CBY33412.1 - 1.1e-14 53.9 0.1 3.8e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY33412.1 - 3.2e-13 49.5 0.0 2.7e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY33412.1 - 1.4e-12 47.6 4.0 3.2e-08 33.7 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY33412.1 - 6.3e-12 45.6 3.9 1.7e-07 31.3 0.0 3.0 3 0 0 3 3 3 2 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY33412.1 - 2.5e-05 24.9 0.0 0.2 12.4 0.0 2.8 3 0 0 3 3 3 2 Glutathione S-transferase N-terminal domain BUD22 PF09073.10 CBY33412.1 - 0.01 15.2 0.7 0.014 14.8 0.7 1.2 1 0 0 1 1 1 0 BUD22 Glutaredoxin PF00462.24 CBY33412.1 - 0.013 15.7 0.0 0.59 10.4 0.1 2.7 2 0 0 2 2 2 0 Glutaredoxin GluRS_N PF18466.1 CBY33412.1 - 0.048 14.1 0.0 18 5.9 0.0 2.9 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain Glyco_hydro_35 PF01301.19 CBY33414.1 - 1e-103 347.3 1.3 1.5e-103 346.8 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY33414.1 - 2.7e-12 46.7 4.0 1.5e-11 44.2 4.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 CBY33414.1 - 0.00017 22.1 0.1 0.0027 18.3 0.0 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain GAD-like PF08887.11 CBY33414.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 GAD-like domain SOAR PF16533.5 CBY33416.1 - 6.6e-29 99.9 4.5 6.6e-29 99.9 4.5 3.1 3 0 0 3 3 3 1 STIM1 Orai1-activating region SAM_2 PF07647.17 CBY33416.1 - 3.1e-05 24.0 0.1 9.1e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY33416.1 - 0.0088 16.5 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 CBY33416.1 - 0.0099 15.7 1.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY33416.1 - 0.055 13.4 5.2 4.8 7.4 0.0 3.9 3 1 0 3 3 3 0 EF-hand domain MARCKS PF02063.17 CBY33416.1 - 0.081 12.9 4.8 0.15 12.1 4.8 1.4 1 0 0 1 1 1 0 MARCKS family EF-hand_1 PF00036.32 CBY33416.1 - 0.086 12.4 7.5 0.088 12.4 0.0 3.4 4 0 0 4 4 4 0 EF hand DUF2639 PF11121.8 CBY33416.1 - 0.16 12.1 0.3 0.59 10.2 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Sec2p PF06428.11 CBY33416.1 - 0.42 10.6 8.0 5.6 7.0 0.1 3.3 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p EF-hand_7 PF13499.6 CBY33416.1 - 0.43 11.1 6.3 1.3 9.5 1.0 3.7 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.6 CBY33416.1 - 0.52 9.9 5.7 3.8 7.2 0.1 2.7 2 0 0 2 2 2 0 EF hand DivIC PF04977.15 CBY33416.1 - 0.74 9.6 3.8 22 4.9 0.0 3.2 3 0 0 3 3 3 0 Septum formation initiator VIT1 PF01988.19 CBY33416.1 - 2.5 7.9 4.5 0.88 9.4 1.4 2.0 2 0 0 2 2 2 0 VIT family Flavi_M PF01004.19 CBY33417.1 - 0.14 11.9 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Tetraspanin PF00335.20 CBY33418.1 - 2.1e-23 83.2 12.5 5.1e-23 82.0 12.5 1.6 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 CBY33418.1 - 2.6e-05 24.3 0.2 2.6e-05 24.3 0.2 2.3 2 1 1 3 3 3 1 CD20-like family Cyt_bd_oxida_I PF01654.17 CBY33418.1 - 0.034 12.8 1.9 0.065 11.8 1.5 1.7 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit I TctB PF07331.11 CBY33418.1 - 0.65 10.3 6.2 7.3 6.9 3.8 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family FixS PF03597.15 CBY33418.1 - 1.2 8.9 3.6 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Phage_holin_2_3 PF16080.5 CBY33419.1 - 0.027 14.2 0.2 0.081 12.7 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage holin family HP1 CcmD PF04995.14 CBY33419.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) zf_C2H2_6 PF18450.1 CBY33420.1 - 0.2 11.4 0.7 0.43 10.3 0.7 1.6 1 0 0 1 1 1 0 Zinc Finger domain O-FucT PF10250.9 CBY33422.1 - 2.3e-09 37.4 0.0 9.1e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Thymosin PF01290.20 CBY33423.1 - 5.7e-57 189.2 65.1 3e-10 39.6 2.4 10.1 9 1 1 10 10 10 10 Thymosin beta-4 family WH2 PF02205.20 CBY33423.1 - 1.6e-06 27.7 34.0 2.2 8.2 0.0 9.1 10 0 0 10 10 10 6 WH2 motif Pentapeptide_4 PF13599.6 CBY33423.1 - 0.00071 19.7 11.9 0.093 12.9 0.3 4.8 3 2 1 4 4 4 2 Pentapeptide repeats (9 copies) Prot_ATP_ID_OB PF16450.5 CBY33423.1 - 0.044 13.7 1.2 28 4.8 0.1 3.4 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain DUF4476 PF14771.6 CBY33423.1 - 0.12 12.7 21.0 0.4 11.0 1.5 5.2 3 1 4 7 7 7 0 Domain of unknown function (DUF4476) DUF2963 PF11178.8 CBY33423.1 - 0.23 11.2 8.2 2.8 7.7 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) RHH_8 PF17723.1 CBY33423.1 - 0.84 9.8 8.1 22 5.3 0.2 4.2 2 1 4 6 6 6 0 Ribbon-Helix-Helix transcriptional regulator family NOD2_WH PF17779.1 CBY33423.1 - 3.4 8.1 5.7 9.8 6.6 0.0 4.2 5 1 1 6 6 6 0 NOD2 winged helix domain DUF4522 PF15022.6 CBY33423.1 - 8.8 6.6 20.8 29 4.9 0.4 5.7 1 1 7 8 8 8 0 Protein of unknown function (DUF4522) CD20 PF04103.15 CBY33424.1 - 0.00013 22.1 6.5 0.00019 21.5 5.0 2.0 1 1 0 1 1 1 1 CD20-like family DUF202 PF02656.15 CBY33424.1 - 0.015 15.8 0.8 0.015 15.8 0.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF5357 PF17310.2 CBY33424.1 - 0.057 12.0 1.8 0.085 11.4 1.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) MerC PF03203.14 CBY33424.1 - 0.086 13.3 4.0 0.19 12.2 4.0 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein DUF308 PF03729.13 CBY33424.1 - 8.6 6.8 16.0 4.1 7.8 0.4 2.6 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Phospholip_A2_1 PF00068.19 CBY33425.1 - 2.4e-20 73.1 7.9 2.4e-20 73.1 7.9 2.3 2 0 0 2 2 2 1 Phospholipase A2 Lig_chan PF00060.26 CBY33426.1 - 4.1e-25 88.4 0.1 6e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Lig_chan-Glu_bd PF10613.9 CBY33426.1 - 1e-15 57.9 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site SBP_bac_3 PF00497.20 CBY33426.1 - 7.1e-13 48.5 0.0 7.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 DUF2407_C PF13373.6 CBY33426.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain Palm_thioest PF02089.15 CBY33427.1 - 3.9e-70 236.4 0.0 4.4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase O-FucT PF10250.9 CBY33428.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Atg31 PF09795.9 CBY33430.1 - 0.059 13.4 0.7 0.099 12.6 0.7 1.4 1 0 0 1 1 1 0 Autophagy-related protein 31 7tm_1 PF00001.21 CBY33431.1 - 8.7e-33 113.8 12.3 1.2e-32 113.3 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Aminotran_3 PF00202.21 CBY33432.1 - 2.9e-86 289.7 0.0 3.4e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NIDO PF06119.14 CBY33433.1 - 0.025 15.5 0.7 0.12 13.4 0.7 2.2 1 1 0 1 1 1 0 Nidogen-like HKR_ArcB_TM PF18415.1 CBY33434.1 - 0.034 14.9 2.5 0.034 14.9 2.5 1.7 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Silic_transp PF03842.13 CBY33434.1 - 0.034 12.4 3.0 0.037 12.3 2.1 1.5 1 1 0 1 1 1 0 Silicon transporter DUF5131 PF07505.11 CBY33434.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Kelch_2 PF07646.15 CBY33435.1 - 0.00099 19.0 3.1 0.83 9.7 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Trypsin PF00089.26 CBY33436.1 - 8.5e-61 205.6 1.3 9.6e-61 205.4 1.3 1.0 1 0 0 1 1 1 1 Trypsin Ion_trans_N PF08412.10 CBY33436.1 - 0.13 11.9 0.2 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 Ion transport protein N-terminal Aminotran_1_2 PF00155.21 CBY33438.1 - 1.5e-39 136.2 0.0 1.9e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CBY33438.1 - 0.00034 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_2 PF12796.7 CBY33439.1 - 3.6e-31 107.6 0.6 2.3e-08 34.5 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY33439.1 - 2.4e-30 104.5 8.5 3.4e-10 40.2 0.1 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY33439.1 - 8e-25 86.6 8.1 2.8e-06 27.5 0.1 6.4 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33439.1 - 7.7e-22 75.0 4.1 0.0025 18.2 0.2 8.3 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 CBY33439.1 - 2.4e-21 75.2 6.3 0.0032 17.8 0.6 7.4 7 0 0 7 7 7 6 Ankyrin repeat DUF3447 PF11929.8 CBY33439.1 - 0.19 11.7 0.4 2.3 8.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) RPEL PF02755.15 CBY33440.1 - 0.4 10.4 2.6 2 8.2 0.0 2.3 2 0 0 2 2 2 0 RPEL repeat Pkinase_Tyr PF07714.17 CBY33441.1 - 2e-74 250.1 0.0 2.5e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33441.1 - 3.7e-39 134.7 0.0 4.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY33441.1 - 0.00086 18.7 0.0 0.0037 16.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY33441.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF4515 PF14988.6 CBY33442.1 - 5.1e-55 186.5 39.8 5.1e-55 186.5 39.8 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4515) Sec34 PF04136.15 CBY33442.1 - 0.36 10.7 25.7 0.098 12.5 3.7 3.3 2 2 1 3 3 3 0 Sec34-like family DUF948 PF06103.11 CBY33442.1 - 6.8 7.0 11.0 0.16 12.2 1.3 2.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Rad10 PF03834.14 CBY33443.1 - 3e-31 107.8 0.1 7.3e-31 106.5 0.1 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CBY33443.1 - 0.00011 22.7 0.4 0.00028 21.4 0.4 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CBY33443.1 - 0.0043 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 CBY33443.1 - 0.013 16.1 0.3 0.91 10.2 0.0 3.3 2 1 2 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 CBY33443.1 - 0.09 12.7 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HMMR_N PF15905.5 CBY33444.1 - 6.3e-05 22.6 17.3 6.3e-05 22.6 17.3 5.9 2 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 CBY33444.1 - 0.0075 16.8 17.6 0.0075 16.8 17.6 7.7 1 1 5 7 7 7 1 Apg6 coiled-coil region Trypan_PARP PF05887.11 CBY33444.1 - 0.0083 16.1 11.9 0.029 14.4 11.9 1.9 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) bZIP_1 PF00170.21 CBY33444.1 - 0.028 14.5 1.1 0.028 14.5 1.1 11.2 6 4 4 11 11 11 0 bZIP transcription factor Galactosyl_T PF01762.21 CBY33446.1 - 1.4e-34 119.6 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF3939 PF13075.6 CBY33446.1 - 0.027 14.5 0.0 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Fringe PF02434.16 CBY33446.1 - 0.042 13.3 0.4 0.072 12.5 0.4 1.3 1 0 0 1 1 1 0 Fringe-like BPS PF08947.10 CBY33446.1 - 0.12 12.2 0.1 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 BPS (Between PH and SH2) Sulfotransfer_1 PF00685.27 CBY33447.1 - 3.7e-30 105.3 0.0 7.8e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY33447.1 - 6.5e-07 29.9 0.0 0.09 13.1 0.0 3.2 1 1 1 3 3 3 3 Sulfotransferase family Slx4 PF09494.10 CBY33448.1 - 0.093 12.7 0.4 0.73 9.8 0.1 2.4 2 1 0 2 2 2 0 Slx4 endonuclease LptF_LptG PF03739.14 CBY33448.1 - 0.12 11.2 0.8 0.17 10.7 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG VF530 PF09905.9 CBY33451.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.0 1 0 0 1 1 1 0 DNA-binding protein VF530 cNMP_binding PF00027.29 CBY33452.1 - 6.4e-42 141.5 0.0 1.5e-20 73.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBY33452.1 - 0.16 11.3 2.0 3.7 6.8 0.2 2.4 2 1 0 2 2 2 0 Protein kinase domain DUF3783 PF12646.7 CBY33452.1 - 0.21 11.5 1.0 2.1 8.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) 7TMR-HDED PF07697.11 CBY33452.1 - 5.5 7.0 10.9 0.42 10.7 0.8 2.8 2 1 1 3 3 3 0 7TM-HD extracellular fn3 PF00041.21 CBY33454.1 - 8.2e-23 80.6 8.4 6.4e-08 32.8 0.0 7.5 7 2 0 7 7 7 5 Fibronectin type III domain Gly_rich PF12810.7 CBY33454.1 - 1.2 9.0 57.1 1.1e+02 2.6 57.1 2.5 1 1 0 1 1 1 0 Glycine rich protein FGGY_N PF00370.21 CBY33455.1 - 1.6e-68 230.9 0.2 2.5e-68 230.3 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBY33455.1 - 3.4e-62 209.7 0.4 6.1e-62 208.9 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain LRR_8 PF13855.6 CBY33456.1 - 5.8e-09 35.6 22.0 2.7e-05 23.8 8.6 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBY33456.1 - 1.3e-08 35.0 27.0 0.00095 19.5 3.7 4.1 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) RIIa PF02197.17 CBY33456.1 - 0.012 15.3 0.1 0.5 10.1 0.0 2.7 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit LRR_1 PF00560.33 CBY33456.1 - 0.013 15.9 22.4 2.7 8.9 0.0 6.1 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY33456.1 - 0.026 14.6 15.8 4.6 7.6 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 CBY33456.1 - 0.065 12.7 11.9 0.32 10.5 2.2 2.6 1 1 2 3 3 3 0 Leucine-rich repeat Homeodomain PF00046.29 CBY33457.1 - 4.2e-25 87.4 4.2 8.4e-25 86.4 2.0 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY33457.1 - 0.01 15.7 1.1 0.026 14.4 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain YdaS_antitoxin PF15943.5 CBY33457.1 - 0.038 13.8 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT EF-hand_7 PF13499.6 CBY33458.1 - 1.4e-05 25.4 3.7 0.18 12.3 2.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY33458.1 - 0.053 13.1 0.2 0.053 13.1 0.2 4.2 5 0 0 5 5 5 0 EF hand CAMSAP_CH PF11971.8 CBY33458.1 - 0.075 12.9 0.2 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 CAMSAP CH domain DUF1007 PF06226.13 CBY33458.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) EF-hand_5 PF13202.6 CBY33458.1 - 3.4 7.3 8.7 1.7 8.3 0.3 3.7 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 CBY33458.1 - 4.8 7.4 9.8 3.4 7.8 0.4 3.9 4 1 0 4 4 4 0 EF-hand domain SNRNP27 PF08648.12 CBY33459.1 - 0.012 15.7 0.4 0.025 14.6 0.4 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins PilO PF04350.13 CBY33459.1 - 0.086 13.0 0.1 1 9.5 0.0 2.2 1 1 1 2 2 2 0 Pilus assembly protein, PilO Peptidase_C2 PF00648.21 CBY33461.1 - 7.4e-75 251.7 0.2 1.1e-74 251.1 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBY33461.1 - 8.8e-39 133.0 0.0 1.7e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Calpain large subunit, domain III EF-hand_6 PF13405.6 CBY33461.1 - 2.1e-06 27.2 0.1 4.9e-05 22.9 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY33461.1 - 5.9e-05 22.3 2.4 0.0002 20.7 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY33461.1 - 8.6e-05 22.9 1.4 0.0017 18.8 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair Rhodanese PF00581.20 CBY33462.1 - 4.7e-12 46.4 0.0 1.5e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain COG2 PF06148.11 CBY33463.1 - 0.0014 18.7 0.8 0.0014 18.7 0.8 2.5 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 CBY33463.1 - 0.0064 17.2 1.9 0.033 14.9 0.5 2.5 1 1 0 2 2 2 1 Occludin homology domain FlxA PF14282.6 CBY33463.1 - 0.036 14.0 3.1 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.6 CBY33463.1 - 0.05 13.0 0.1 0.31 10.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FliD_C PF07195.12 CBY33463.1 - 0.08 12.4 4.3 2.6 7.4 4.3 2.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus kleA_kleC PF17383.2 CBY33463.1 - 0.17 12.2 0.8 2.1 8.8 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A UPF0242 PF06785.11 CBY33463.1 - 0.28 11.3 5.1 0.19 11.8 1.8 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 CBY33463.1 - 0.45 10.8 3.9 1 9.6 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CBY33463.1 - 0.72 10.2 7.2 3.5 8.0 0.1 3.1 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.11 CBY33463.1 - 2.6 8.2 10.6 1.1 9.4 1.1 3.5 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF16 PF01519.16 CBY33463.1 - 4 8.0 7.6 0.66 10.5 1.5 2.6 2 1 0 3 3 3 0 Protein of unknown function DUF16 Kelch_5 PF13854.6 CBY33464.1 - 0.08 13.0 0.1 0.08 13.0 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY33464.1 - 0.11 12.5 0.6 31 4.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Pkinase PF00069.25 CBY33466.1 - 1.4e-31 109.8 0.7 2.1e-31 109.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33466.1 - 3.8e-20 72.2 0.0 5.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33466.1 - 2.9e-09 36.7 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY33466.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY33466.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zona_pellucida PF00100.23 CBY33467.1 - 2e-05 24.5 0.1 2.2e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Kelch_1 PF01344.25 CBY33468.1 - 4.8e-08 32.5 0.2 0.0015 18.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY33468.1 - 1.3e-07 31.6 4.5 0.4 11.0 0.0 4.6 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CBY33468.1 - 4.2e-06 26.5 0.7 0.5 10.4 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CBY33468.1 - 0.00083 19.6 4.0 0.12 12.7 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY33468.1 - 0.0075 16.3 3.8 11 6.1 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY33468.1 - 0.19 11.8 12.3 1.1 9.3 0.0 4.1 5 0 0 5 5 5 0 Kelch motif rve PF00665.26 CBY33469.1 - 3.4e-20 72.4 0.0 7.2e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY33469.1 - 9.9e-12 44.8 0.3 2.3e-11 43.6 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CBY33469.1 - 4.5e-06 26.9 0.0 7.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase adh_short PF00106.25 CBY33471.1 - 2.8e-09 36.7 0.0 4.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY33471.1 - 1.1e-07 31.7 0.0 7e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PAP_assoc PF03828.19 CBY33472.1 - 9.7e-18 64.1 0.0 3.1e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY33472.1 - 5.4e-14 52.2 0.0 1.2e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Luciferase_N PF05295.11 CBY33472.1 - 0.04 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain TniQ PF06527.11 CBY33472.1 - 0.049 14.3 0.1 0.049 14.3 0.1 2.2 3 1 0 3 3 3 0 TniQ zf-C3HC4 PF00097.25 CBY33473.1 - 2.1e-05 24.3 7.1 4.2e-05 23.3 7.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY33473.1 - 0.0002 21.3 8.9 0.00037 20.4 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY33473.1 - 0.00079 19.2 11.2 0.0018 18.1 11.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY33473.1 - 0.0024 18.0 1.9 0.0024 18.0 1.9 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING BshC PF10079.9 CBY33473.1 - 0.0065 15.3 1.2 0.0082 14.9 1.2 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC zf-RING_2 PF13639.6 CBY33473.1 - 0.011 16.0 8.2 0.021 15.1 8.2 1.5 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 CBY33473.1 - 0.022 14.6 6.0 0.044 13.6 6.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY33473.1 - 0.022 14.6 8.4 0.049 13.5 8.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY33473.1 - 0.036 14.2 6.3 0.17 12.1 6.5 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 CBY33473.1 - 0.073 13.1 1.2 0.073 13.1 1.2 1.9 1 1 1 2 2 2 0 RING-type zinc-finger VPS11_C PF12451.8 CBY33473.1 - 0.08 13.2 0.9 0.15 12.3 0.9 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CtIP_N PF10482.9 CBY33473.1 - 0.11 12.6 6.0 0.16 12.0 4.5 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain zf-RING_4 PF14570.6 CBY33473.1 - 0.14 12.0 9.7 0.13 12.0 7.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain YabA PF06156.13 CBY33473.1 - 0.19 12.4 8.4 3.5 8.3 0.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA FeS PF04060.13 CBY33473.1 - 0.58 9.9 8.8 6.1 6.6 8.8 2.3 1 1 0 1 1 1 0 Putative Fe-S cluster ADIP PF11559.8 CBY33473.1 - 0.81 9.8 8.0 3.2 7.8 5.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TolA_bind_tri PF16331.5 CBY33473.1 - 0.94 9.6 6.3 2.6 8.2 0.9 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Baculo_IE-1 PF05290.11 CBY33473.1 - 0.95 9.4 5.8 0.6 10.1 3.8 1.7 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DHR10 PF18595.1 CBY33473.1 - 4.8 7.3 11.5 1.3 9.1 0.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 CBY33473.1 - 6.2 7.2 9.2 32 5.0 3.1 2.9 2 1 0 3 3 3 0 Csm1 N-terminal domain Tudor-knot PF11717.8 CBY33474.1 - 4.2e-08 33.0 2.2 8.5e-08 32.0 2.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 CBY33474.1 - 0.0062 16.9 0.5 0.022 15.1 0.5 2.0 1 0 0 1 1 1 1 PWWP domain Agenet PF05641.12 CBY33474.1 - 0.018 15.5 0.5 0.047 14.2 0.5 1.8 1 0 0 1 1 1 0 Agenet domain FapA PF03961.13 CBY33474.1 - 0.94 8.0 3.9 0.32 9.5 0.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A CBF PF03914.17 CBY33475.1 - 2.2e-22 79.9 0.6 2.2e-22 79.9 0.6 1.6 2 0 0 2 2 2 1 CBF/Mak21 family Glyco_hydro_18 PF00704.28 CBY33476.1 - 5.3e-13 49.4 0.0 8.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_2b PF00587.25 CBY33477.1 - 1.9e-38 132.3 0.0 3.3e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBY33477.1 - 1.4e-13 51.0 4.5 5.9e-12 45.8 1.1 3.2 2 1 2 4 4 4 1 Seryl-tRNA synthetase N-terminal domain FAD_SOX PF18371.1 CBY33477.1 - 0.078 13.3 0.0 0.56 10.6 0.0 2.4 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase CPBP PF02517.16 CBY33478.1 - 3.3e-13 49.8 5.4 3.3e-13 49.8 5.4 1.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease FPN1 PF06963.12 CBY33479.1 - 7.6e-80 268.6 11.8 6e-78 262.3 11.8 2.0 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_C2 PF00648.21 CBY33480.1 - 2.9e-56 190.7 0.0 3.9e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease SAP PF02037.27 CBY33481.1 - 0.18 11.6 1.0 0.39 10.5 0.2 2.0 2 0 0 2 2 2 0 SAP domain Connexin PF00029.19 CBY33482.1 - 4.2e-58 196.9 8.1 6.8e-58 196.2 8.1 1.3 1 1 0 1 1 1 1 Connexin Tho2 PF11262.8 CBY33482.1 - 0.0072 15.6 0.8 0.058 12.6 0.2 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 AAA_17 PF13207.6 CBY33482.1 - 0.077 13.4 3.7 0.11 12.9 3.7 1.2 1 0 0 1 1 1 0 AAA domain Plasmod_dom_1 PF09715.10 CBY33482.1 - 0.33 11.1 4.1 0.23 11.5 1.1 2.2 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Trypsin PF00089.26 CBY33483.1 - 8.5e-26 91.1 3.6 1.2e-25 90.7 3.6 1.2 1 0 0 1 1 1 1 Trypsin Phospholip_A2_1 PF00068.19 CBY33484.1 - 1.8e-13 50.9 6.9 1.8e-13 50.9 6.9 1.9 1 1 1 2 2 2 1 Phospholipase A2 Glyco_hydro_9 PF00759.19 CBY33485.1 - 1.8e-131 439.4 13.1 2.5e-131 438.9 13.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_4_9 PF02018.17 CBY33485.1 - 1.9e-06 28.2 0.2 5e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain TPR_12 PF13424.6 CBY33485.1 - 0.092 13.1 1.3 7.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 CBY33486.1 - 7.5e-13 48.6 6.3 1.2e-12 47.9 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY33486.1 - 3.7e-10 39.5 6.7 5.8e-10 38.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY33486.1 - 5.4e-08 32.7 3.0 8.4e-08 32.1 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY33486.1 - 1.1e-07 31.6 5.0 2.1e-07 30.7 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY33486.1 - 1.4e-07 31.1 1.7 3.2e-07 30.0 1.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBY33486.1 - 6.5e-07 29.3 2.9 1.2e-06 28.4 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY33486.1 - 2.6e-06 27.6 8.3 7.8e-06 26.1 8.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY33486.1 - 5.2e-06 26.2 3.4 7.8e-06 25.7 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY33486.1 - 3.3e-05 23.4 2.5 6.1e-05 22.6 2.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY33486.1 - 0.00094 19.0 8.4 0.028 14.3 8.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CBY33486.1 - 0.025 14.6 2.3 0.025 14.6 2.3 2.1 2 1 0 2 2 2 0 Zinc-finger zf-ANAPC11 PF12861.7 CBY33486.1 - 0.039 14.0 1.5 0.08 13.0 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CBY33486.1 - 0.071 13.3 3.0 0.16 12.1 3.0 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CBY33486.1 - 0.24 11.6 2.9 0.61 10.3 2.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CBY33486.1 - 0.28 11.5 5.5 0.86 10.0 5.4 1.9 1 1 1 2 2 2 0 RING-like domain zf-RING_4 PF14570.6 CBY33486.1 - 0.36 10.7 6.5 0.82 9.5 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 CBY33486.1 - 0.42 11.1 2.4 0.63 10.5 0.7 2.1 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.8 CBY33486.1 - 0.76 10.0 5.3 4.9 7.4 5.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Sema PF01403.19 CBY33488.1 - 5.2e-21 75.0 0.4 7.9e-20 71.1 0.0 2.7 2 1 0 2 2 2 1 Sema domain Baculo_PEP_C PF04513.12 CBY33488.1 - 0.017 15.1 0.7 0.84 9.7 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 CBY33488.1 - 0.029 14.7 6.9 3.1 8.1 0.7 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1351 PF07083.11 CBY33488.1 - 0.076 12.8 10.6 3.6 7.3 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) DASH_Dam1 PF08653.10 CBY33488.1 - 0.3 10.9 2.7 25 4.8 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 HrpB7 PF09486.10 CBY33488.1 - 0.49 10.8 8.1 2.9 8.3 0.3 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF724 PF05266.14 CBY33488.1 - 0.71 9.7 10.0 0.055 13.3 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 CBY33488.1 - 1.1 9.9 11.7 11 6.8 1.8 3.5 2 1 1 3 3 3 0 Initiation control protein YabA SlyX PF04102.12 CBY33488.1 - 1.3 9.7 6.7 41 4.9 0.0 3.7 3 1 0 3 3 3 0 SlyX MerR-DNA-bind PF09278.11 CBY33488.1 - 1.3 9.6 5.6 51 4.5 0.1 3.9 4 0 0 4 4 4 0 MerR, DNA binding Fib_alpha PF08702.10 CBY33488.1 - 1.3 9.2 13.0 0.2 11.8 4.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CBY33488.1 - 1.4 9.5 9.1 8 7.0 0.5 3.7 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein STAT_alpha PF01017.20 CBY33488.1 - 1.6 8.6 10.8 0.25 11.3 5.9 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF948 PF06103.11 CBY33488.1 - 2 8.8 6.0 18 5.7 0.4 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 CBY33488.1 - 2 6.2 8.6 0.59 8.0 3.6 2.0 1 1 1 2 2 2 0 Prominin DHR10 PF18595.1 CBY33488.1 - 2.2 8.4 16.0 3.3 7.8 2.0 3.5 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Ax_dynein_light PF10211.9 CBY33488.1 - 4.5 7.2 12.8 2.9 7.8 3.3 3.3 2 1 1 3 3 3 0 Axonemal dynein light chain Osmo_CC PF08946.10 CBY33488.1 - 5.6 7.3 7.9 5.8 7.2 0.3 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Nsp1_C PF05064.13 CBY33488.1 - 6.7 6.5 7.9 7 6.5 0.8 2.8 3 1 0 3 3 2 0 Nsp1-like C-terminal region ZapB PF06005.12 CBY33488.1 - 7.7 7.0 8.8 43 4.6 0.3 3.7 3 1 0 3 3 3 0 Cell division protein ZapB EGF_3 PF12947.7 CBY33489.1 - 8e-18 64.3 71.7 3.2e-08 33.6 15.5 4.9 5 1 1 6 6 6 3 EGF domain cEGF PF12662.7 CBY33489.1 - 5.2e-10 39.1 32.1 5.6e-07 29.4 5.5 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY33489.1 - 8e-10 38.8 13.9 8e-10 38.8 13.9 4.8 5 0 0 5 5 5 3 Calcium-binding EGF domain EGF_MSP1_1 PF12946.7 CBY33489.1 - 2.8e-07 30.5 39.5 0.0034 17.4 6.5 4.7 4 0 0 4 4 4 3 MSP1 EGF domain 1 EGF PF00008.27 CBY33489.1 - 6.8e-07 29.5 55.0 0.00076 19.7 10.7 4.4 4 1 0 4 4 4 3 EGF-like domain hEGF PF12661.7 CBY33489.1 - 0.0034 17.9 5.3 0.0034 17.9 5.3 4.5 5 0 0 5 5 5 2 Human growth factor-like EGF Helicase_C_2 PF13307.6 CBY33490.1 - 2.6e-50 171.0 0.0 6.7e-50 169.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBY33490.1 - 4.4e-47 160.0 0.9 8.5e-47 159.0 0.9 1.5 1 0 0 1 1 1 1 DEAD_2 PhoH PF02562.16 CBY33490.1 - 0.00014 21.4 0.0 0.068 12.6 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 CBY33490.1 - 0.00039 20.5 0.0 1 9.3 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY33490.1 - 0.013 15.2 0.0 0.15 11.8 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY33490.1 - 0.041 14.2 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain EMC1_C PF07774.13 CBY33491.1 - 9.8e-57 192.1 0.0 1.5e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PLAC8 PF04749.17 CBY33492.1 - 3.7e-15 56.7 13.8 6.1e-15 56.0 13.8 1.3 1 0 0 1 1 1 1 PLAC8 family Mob1_phocein PF03637.17 CBY33493.1 - 2.7e-55 187.0 0.5 3.2e-55 186.7 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family PHD PF00628.29 CBY33494.1 - 2e-08 34.0 4.1 4.4e-08 32.9 4.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY33494.1 - 7.3e-05 22.2 4.3 0.00014 21.3 4.3 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 CBY33494.1 - 0.051 13.5 1.0 0.14 12.0 1.0 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_10 PF10058.9 CBY33494.1 - 0.14 11.9 1.5 0.39 10.5 1.5 1.8 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-CSL PF05207.13 CBY33494.1 - 0.59 9.9 2.6 2.5 7.9 2.6 2.1 1 1 0 1 1 1 0 CSL zinc finger TPD PF14811.6 CBY33495.1 - 2.8 7.8 6.3 29 4.5 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function TPD sequence-motif WD40 PF00400.32 CBY33496.1 - 1e-23 83.2 17.8 0.00024 21.8 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PNPase_C PF12111.8 CBY33496.1 - 0.012 15.0 0.6 0.031 13.7 0.6 1.7 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal Coatomer_WDAD PF04053.14 CBY33496.1 - 0.029 13.4 0.3 0.16 11.0 0.3 2.0 1 1 0 1 1 1 0 Coatomer WD associated region Fib_alpha PF08702.10 CBY33496.1 - 0.057 13.6 0.8 0.11 12.6 0.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CBY33496.1 - 0.29 11.8 1.8 1.4 9.6 1.8 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Kelch_1 PF01344.25 CBY33497.1 - 2.1e-59 196.8 9.9 1.4e-13 50.1 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY33497.1 - 1.6e-33 113.9 0.5 1.2e-05 25.5 0.0 6.4 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 CBY33497.1 - 8.6e-23 80.7 0.1 1.6e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 CBY33497.1 - 3.2e-20 71.9 0.3 0.0052 16.8 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY33497.1 - 1e-19 69.6 1.4 8.2e-05 22.4 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CBY33497.1 - 3.9e-19 68.5 0.4 8.3e-05 22.8 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain BACK PF07707.15 CBY33497.1 - 4.5e-17 62.0 4.4 1.4e-16 60.5 2.7 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 CBY33497.1 - 1.3e-10 41.0 3.8 0.0017 18.3 0.0 5.2 5 0 0 5 5 5 3 Kelch motif ATP_bind_1 PF03029.17 CBY33498.1 - 5.1e-84 281.8 0.2 5.9e-84 281.6 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CBY33498.1 - 0.0041 16.9 0.0 0.035 13.9 0.0 2.4 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 CBY33498.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 CBY33498.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBY33498.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY33498.1 - 0.026 15.1 0.4 0.089 13.3 0.0 2.2 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBY33498.1 - 0.046 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY33498.1 - 0.074 13.4 0.0 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CBY33498.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CBY33498.1 - 0.1 12.5 0.0 17 5.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBY33498.1 - 0.12 11.7 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 CBY33498.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 CBY33498.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBY33498.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Abhydrolase_6 PF12697.7 CBY33500.1 - 1.2e-26 94.7 0.0 1.4e-26 94.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY33500.1 - 2.9e-12 46.4 0.1 3.2e-12 46.2 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY33500.1 - 3.2e-10 40.1 0.1 3.6e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CBY33500.1 - 3.2e-06 27.4 0.0 6.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 CBY33500.1 - 0.0064 16.3 0.3 0.31 10.8 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 CBY33500.1 - 0.0065 16.2 0.2 0.01 15.6 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 CBY33500.1 - 0.01 15.7 0.3 0.046 13.6 0.3 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 CBY33500.1 - 0.012 15.1 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 CBY33500.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 CBY33500.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF4663 PF15668.5 CBY33501.1 - 2.3e-17 63.1 0.0 5e-11 42.3 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4663) Tubulin PF00091.25 CBY33502.1 - 2.1e-69 233.7 0.0 2.9e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY33502.1 - 7e-52 174.9 0.0 1.1e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY33502.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tetraspanin PF00335.20 CBY33503.1 - 4.2e-09 36.5 1.6 4.8e-09 36.3 1.6 1.1 1 0 0 1 1 1 1 Tetraspanin family ATP-synt_C PF00137.21 CBY33504.1 - 2.1e-11 44.0 14.0 3.1e-11 43.5 14.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit C Ets PF00178.22 CBY33505.1 - 2e-31 108.3 0.2 2e-31 108.3 0.2 1.9 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 CBY33505.1 - 2.9e-14 52.8 0.1 5.3e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AKNA PF12443.8 CBY33506.1 - 0.0048 17.5 0.7 0.0071 17.0 0.7 1.3 1 0 0 1 1 1 1 AT-hook-containing transcription factor FBP_C PF16571.5 CBY33506.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger KIP1 PF07765.12 CBY33506.1 - 0.12 12.5 3.9 5.3 7.2 0.1 2.3 1 1 1 2 2 2 0 KIP1-like protein NAM PF02365.15 CBY33507.1 - 0.0054 17.6 0.5 0.0071 17.3 0.5 1.3 1 0 0 1 1 1 1 No apical meristem (NAM) protein MadM PF03818.13 CBY33508.1 - 0.57 10.1 4.3 1.3 8.9 0.1 2.7 3 1 0 3 3 3 0 Malonate/sodium symporter MadM subunit CutC PF03932.14 CBY33509.1 - 9.5e-45 152.6 0.1 1.2e-44 152.2 0.1 1.1 1 0 0 1 1 1 1 CutC family TMP-TENI PF02581.17 CBY33509.1 - 2.2e-05 23.8 0.2 0.00014 21.3 0.0 2.2 3 0 0 3 3 3 1 Thiamine monophosphate synthase His_biosynth PF00977.21 CBY33509.1 - 0.00025 20.6 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CBY33509.1 - 0.0014 18.0 0.1 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family AP_endonuc_2 PF01261.24 CBY33509.1 - 0.016 14.7 0.0 0.14 11.6 0.0 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel QRPTase_C PF01729.19 CBY33509.1 - 0.017 14.9 0.1 0.32 10.8 0.0 2.4 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF745 PF05335.13 CBY33510.1 - 0.009 15.8 1.2 0.009 15.8 1.2 5.3 3 1 2 6 6 6 1 Protein of unknown function (DUF745) KNOX2 PF03791.13 CBY33510.1 - 1.1 8.9 4.6 2.4 7.7 0.2 3.6 3 0 0 3 3 3 0 KNOX2 domain ThrE PF06738.12 CBY33510.1 - 1.3 8.3 9.4 0.066 12.6 0.8 2.9 3 0 0 3 3 3 0 Putative threonine/serine exporter SAM_2 PF07647.17 CBY33511.1 - 0.00062 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ATP-synt_D PF01813.17 CBY33512.1 - 1.8e-71 240.0 0.9 1.8e-71 240.0 0.9 1.6 2 0 0 2 2 2 1 ATP synthase subunit D HECT PF00632.25 CBY33513.1 - 1.6e-61 208.5 0.0 3e-61 207.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PABP PF00658.18 CBY33513.1 - 1.7e-08 34.5 0.2 4.5e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Trypsin PF00089.26 CBY33514.1 - 1.5e-52 178.6 0.2 1.9e-52 178.3 0.2 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY33514.1 - 1.7e-06 28.4 0.1 3.7e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY33514.1 - 3.7e-06 27.9 0.0 7.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ldl_recept_a PF00057.18 CBY33514.1 - 5e-06 26.6 13.1 6.3e-06 26.3 11.1 2.2 1 1 0 1 1 1 1 Low-density lipoprotein receptor domain class A Glycos_transf_2 PF00535.26 CBY33515.1 - 2.7e-27 95.7 0.0 4.6e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY33515.1 - 2.8e-16 59.9 0.4 6e-16 58.8 0.4 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY33515.1 - 6.3e-07 29.0 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CDtoxinA PF03498.14 CBY33515.1 - 0.0029 17.2 0.4 0.0052 16.4 0.4 1.4 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 CBY33515.1 - 0.042 14.6 0.1 0.27 12.0 0.1 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RLAN PF14401.6 CBY33515.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain GIT_CC PF16559.5 CBY33516.1 - 0.0049 16.7 4.4 0.46 10.4 1.3 2.8 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 CBY33516.1 - 2 8.7 10.5 1.8 8.9 2.5 3.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Snf7 PF03357.21 CBY33517.1 - 8.2e-39 133.0 27.7 8.2e-39 133.0 27.7 1.2 1 1 0 1 1 1 1 Snf7 DUF2570 PF10828.8 CBY33517.1 - 1.7 8.5 14.9 0.055 13.3 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) YlqD PF11068.8 CBY33517.1 - 2.1 8.7 16.4 6 7.3 6.3 2.3 1 1 1 2 2 2 0 YlqD protein V-ATPase_H_C PF11698.8 CBY33517.1 - 5.2 7.2 9.0 13 5.9 0.4 2.3 1 1 1 2 2 2 0 V-ATPase subunit H Cytochrom_C PF00034.21 CBY33518.1 - 1.5e-11 45.3 0.1 1.8e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBY33518.1 - 0.00027 21.2 4.3 0.00072 19.8 4.3 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CBY33518.1 - 0.012 15.3 2.6 0.02 14.6 2.6 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain Pkinase PF00069.25 CBY33519.1 - 1.6e-62 211.3 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33519.1 - 3.1e-40 138.1 0.0 4.4e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY33519.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PglD_N PF17836.1 CBY33519.1 - 0.0018 18.9 0.1 0.0052 17.4 0.1 1.7 1 0 0 1 1 1 1 PglD N-terminal domain Kinase-like PF14531.6 CBY33519.1 - 0.029 13.7 0.1 8.7 5.6 0.0 2.9 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 CBY33519.1 - 0.071 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 CBY33520.1 - 1.7e-44 151.5 0.0 1e-43 148.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY33520.1 - 8.7e-11 41.6 0.1 3e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBY33520.1 - 2.4e-09 36.8 0.0 6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY33520.1 - 8.6e-09 35.7 0.1 3.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY33520.1 - 8.9e-09 35.5 0.3 4.7e-08 33.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY33520.1 - 1.4e-06 28.8 0.2 0.00081 19.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY33520.1 - 3.3e-05 23.2 0.2 7.7e-05 22.0 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY33520.1 - 4.9e-05 23.1 0.0 0.00023 20.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CBY33520.1 - 0.00016 21.7 0.1 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBY33520.1 - 0.00022 21.5 0.8 0.043 14.1 0.8 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBY33520.1 - 0.00023 20.5 0.0 0.00084 18.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 CBY33520.1 - 0.00024 21.5 0.0 0.00079 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBY33520.1 - 0.00051 19.5 0.1 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBY33520.1 - 0.00086 19.6 0.0 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY33520.1 - 0.0011 19.6 0.0 0.0094 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBY33520.1 - 0.0012 19.0 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 CBY33520.1 - 0.0028 17.4 0.3 0.53 10.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.12 CBY33520.1 - 0.0033 17.4 0.1 0.037 14.0 0.0 2.4 3 0 0 3 3 2 1 NACHT domain IstB_IS21 PF01695.17 CBY33520.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 CBY33520.1 - 0.0091 15.9 0.1 0.065 13.2 0.0 2.4 3 0 0 3 3 3 1 NTPase TsaE PF02367.17 CBY33520.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 CBY33520.1 - 0.016 15.1 0.8 0.13 12.1 0.0 2.4 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CBY33520.1 - 0.02 14.5 0.7 0.11 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY33520.1 - 0.023 14.2 0.1 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBY33520.1 - 0.028 13.7 0.0 0.08 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 CBY33520.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CBY33520.1 - 0.05 13.0 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 CBY33520.1 - 0.059 12.5 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 CBY33520.1 - 0.074 12.8 0.1 0.18 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY33520.1 - 0.076 13.4 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 CBY33520.1 - 0.093 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 CBY33520.1 - 0.12 11.7 0.8 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 CBY33520.1 - 0.13 12.7 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 1 0 ABC transporter GrpE PF01025.19 CBY33520.1 - 1 9.0 4.8 0.76 9.4 0.1 2.4 3 0 0 3 3 2 0 GrpE PARG_cat PF05028.14 CBY33521.1 - 8.1e-76 255.5 0.5 1.2e-75 254.9 0.2 1.4 1 1 1 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) PARG_cat PF05028.14 CBY33522.1 - 1.3e-111 373.2 0.2 3.3e-111 371.8 0.0 1.6 2 0 0 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1798 PF08807.10 CBY33522.1 - 0.059 13.5 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) MitMem_reg PF13012.6 CBY33522.1 - 0.17 12.3 0.0 2.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Pex19 PF04614.12 CBY33522.1 - 7.4 6.3 6.7 1.1 9.0 0.4 2.4 3 0 0 3 3 3 0 Pex19 protein family PBP PF01161.20 CBY33523.1 - 1.1e-07 32.2 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-C2H2_9 PF16293.5 CBY33524.1 - 0.0023 17.8 0.2 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 CBY33524.1 - 0.0042 17.4 0.5 0.01 16.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY33524.1 - 0.046 14.2 0.3 0.21 12.1 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY33524.1 - 0.08 13.3 0.3 4.7 7.6 0.0 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) LexA_DNA_bind PF01726.16 CBY33524.1 - 0.086 12.6 1.7 1.1 9.1 0.4 2.5 1 1 1 2 2 2 0 LexA DNA binding domain AAA_23 PF13476.6 CBY33524.1 - 0.089 13.3 5.1 0.12 12.9 5.1 1.3 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 CBY33524.1 - 0.096 13.6 0.1 0.23 12.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY33524.1 - 0.32 11.3 3.4 0.32 11.3 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FSH1 PF03959.13 CBY33526.1 - 2.7e-46 157.9 0.1 1.2e-45 155.8 0.1 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CBY33526.1 - 0.095 12.5 0.2 0.24 11.2 0.2 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Motile_Sperm PF00635.26 CBY33527.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Kinesin PF00225.23 CBY33528.1 - 8.2e-36 123.6 1.8 5.8e-35 120.8 1.8 2.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY33528.1 - 1e-08 35.3 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Tmemb_185A PF10269.9 CBY33529.1 - 5.3e-42 144.2 21.4 7.1e-42 143.8 21.4 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein EMP70 PF02990.16 CBY33529.1 - 0.72 8.5 17.0 0.68 8.5 3.4 2.6 1 1 1 2 2 2 0 Endomembrane protein 70 Peptidase_C2 PF00648.21 CBY33530.1 - 5.9e-70 235.6 0.4 1e-69 234.8 0.4 1.4 1 1 0 1 1 1 1 Calpain family cysteine protease EGF_CA PF07645.15 CBY33531.1 - 3.6e-37 126.3 112.3 7.7e-06 26.0 11.6 7.7 7 0 0 7 7 7 7 Calcium-binding EGF domain PKD_channel PF08016.12 CBY33531.1 - 1.8e-13 50.0 6.5 1.8e-13 50.0 6.5 2.0 2 0 0 2 2 2 1 Polycystin cation channel EGF_3 PF12947.7 CBY33531.1 - 7.7e-06 26.0 81.5 0.0035 17.5 1.2 8.5 7 1 0 7 7 7 6 EGF domain Peptidase_M28 PF04389.17 CBY33533.1 - 5.2e-23 81.8 0.0 8.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CBY33533.1 - 3e-06 27.2 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CBY33533.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TFR_dimer PF04253.15 CBY33533.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Piwi PF02171.17 CBY33535.1 - 2.3e-56 191.3 0.0 3.7e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY33535.1 - 8.9e-10 39.3 0.0 1.7e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY33535.1 - 0.0014 18.3 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Mo25 PF08569.11 CBY33535.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Mo25-like ArgoL2 PF16488.5 CBY33535.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Argonaute linker 2 domain Troponin PF00992.20 CBY33536.1 - 2.1e-23 83.1 43.8 1.7e-22 80.2 37.4 2.0 1 1 1 2 2 2 2 Troponin DUF2151 PF10221.9 CBY33536.1 - 0.17 10.4 14.5 0.2 10.2 14.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4778 PF16008.5 CBY33536.1 - 1.3 9.0 19.6 1.6 8.7 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) zf-HC5HC2H_2 PF13832.6 CBY33537.1 - 1.9e-24 85.9 6.2 1.9e-24 85.9 6.2 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY33537.1 - 6.8e-19 67.9 4.5 6.8e-19 67.9 4.5 3.6 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CBY33537.1 - 4.6e-12 45.3 6.2 4.6e-12 45.3 6.2 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CBY33537.1 - 3.4e-09 36.5 10.7 3.4e-09 36.5 10.7 2.8 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 CBY33537.1 - 1.5e-05 25.5 0.0 1.5e-05 25.5 0.0 4.6 6 1 0 6 6 6 1 Enhancer of polycomb-like tRNA_synthFbeta PF17759.1 CBY33538.1 - 2e-43 148.3 0.0 3.1e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CBY33538.1 - 2.9e-28 97.9 0.0 6.4e-27 93.6 0.2 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CBY33538.1 - 1.3e-27 96.5 0.0 2.4e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CBY33538.1 - 9.9e-15 54.6 0.1 2.2e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 CBY33538.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) NAC PF01849.18 CBY33539.1 - 1.5e-26 92.2 0.1 2.8e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain Ank_2 PF12796.7 CBY33540.1 - 4.3e-38 129.8 21.3 5.1e-20 71.8 4.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CBY33540.1 - 6.4e-32 108.6 12.0 4.7e-07 30.0 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CBY33540.1 - 8.4e-29 99.6 6.7 1.1e-11 45.0 0.2 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33540.1 - 7.4e-28 93.5 8.5 1.8e-05 24.7 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CBY33540.1 - 5.7e-18 64.8 8.6 5.2e-07 29.8 0.1 5.5 2 1 4 6 6 6 4 Ankyrin repeats (many copies) DUF4071 PF13281.6 CBY33540.1 - 0.013 14.6 0.1 0.097 11.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4071) adh_short PF00106.25 CBY33542.1 - 1e-27 96.9 0.0 1.2e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY33542.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY33542.1 - 0.00034 20.6 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY33542.1 - 0.0022 17.9 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CBY33542.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 CBY33542.1 - 0.13 11.6 2.2 6 6.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family 7tm_1 PF00001.21 CBY33543.1 - 0.00018 20.9 0.1 0.0003 20.2 0.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Alfin PF12165.8 CBY33543.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Alfin DUF2781 PF10914.8 CBY33543.1 - 0.036 14.5 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) LMBR1 PF04791.16 CBY33543.1 - 0.041 12.8 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 CBY33546.1 - 1.8e-17 63.9 1.2 2.4e-17 63.5 1.2 1.2 1 0 0 1 1 1 1 Connexin Connexin PF00029.19 CBY33547.1 - 3.2e-23 82.7 0.2 3.6e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 Connexin DUF2070 PF09843.9 CBY33548.1 - 0.88 7.8 7.0 1 7.6 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) bZIP_1 PF00170.21 CBY33549.1 - 1e-09 38.3 11.4 4.3e-09 36.3 11.4 2.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY33549.1 - 4.7e-07 29.8 11.5 4.7e-07 29.8 11.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY33549.1 - 0.019 15.5 3.2 0.019 15.5 3.2 3.1 3 0 0 3 3 3 0 bZIP Maf transcription factor zf-C2H2_jaz PF12171.8 CBY33550.1 - 3.2e-06 27.3 0.6 7.3e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY33550.1 - 0.0013 19.0 0.3 0.0026 18.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY33550.1 - 0.0023 17.7 3.8 0.0088 15.8 3.8 2.0 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY33550.1 - 0.0047 17.2 2.7 0.02 15.2 1.3 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) MRNIP PF15749.5 CBY33550.1 - 0.022 15.5 5.3 0.022 15.5 5.3 2.8 2 1 0 2 2 2 0 MRN-interacting protein RNase_T PF00929.24 CBY33550.1 - 0.043 14.4 0.1 0.12 12.9 0.1 1.9 1 1 0 1 1 1 0 Exonuclease Pkinase PF00069.25 CBY33551.1 - 2.5e-54 184.4 0.0 3.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33551.1 - 3.4e-27 95.4 0.0 4.5e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_9 PF13901.6 CBY33551.1 - 5.3e-07 29.8 0.9 7.6e-07 29.3 0.3 1.5 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon Pkinase_fungal PF17667.1 CBY33551.1 - 0.00015 20.7 0.0 0.0002 20.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY33551.1 - 0.0041 16.5 0.0 0.0058 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY33551.1 - 0.0086 15.5 0.0 0.16 11.3 0.0 2.0 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY33551.1 - 0.024 14.6 0.0 0.28 11.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family BBS1 PF14779.6 CBY33552.1 - 2.4e-73 246.7 0.0 6.4e-72 242.1 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 CBY33552.1 - 5.6e-07 29.3 0.0 9.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CBY33552.1 - 8.1e-07 29.1 1.5 0.00015 21.8 0.2 3.7 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region STAS PF01740.21 CBY33552.1 - 0.0068 16.0 0.1 0.035 13.8 0.1 2.2 2 0 0 2 2 2 1 STAS domain Peptidase_M3 PF01432.20 CBY33553.1 - 2.4e-07 30.4 0.0 3.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Cpn60_TCP1 PF00118.24 CBY33554.1 - 2.9e-86 290.1 13.9 5.5e-86 289.2 13.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DZF PF07528.14 CBY33555.1 - 5.4e-28 98.3 0.0 3.3e-27 95.7 0.0 2.3 2 0 0 2 2 2 1 DZF domain dsrm PF00035.26 CBY33555.1 - 7.5e-20 71.4 2.8 2.8e-06 27.9 0.1 3.9 3 0 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY33555.1 - 7.8e-07 29.2 3.1 0.007 16.5 0.1 4.1 3 1 0 3 3 3 3 Dicer dimerisation domain HDV_ag PF01517.18 CBY33555.1 - 0.15 11.9 2.3 1.3 8.8 0.2 2.3 1 1 0 2 2 2 0 Hepatitis delta virus delta antigen DuoxA PF10204.9 CBY33556.1 - 8.4e-68 228.4 7.4 1.2e-67 227.9 7.4 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Carb_anhydrase PF00194.21 CBY33558.1 - 5e-75 252.3 0.0 5.9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Trypan_PARP PF05887.11 CBY33558.1 - 0.0051 16.8 9.1 0.0092 16.0 9.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TSP_1 PF00090.19 CBY33560.1 - 0.00017 21.8 19.9 0.0018 18.4 11.0 11.1 13 0 0 13 13 13 2 Thrombospondin type 1 domain DUF5052 PF16475.5 CBY33560.1 - 0.074 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) EGF PF00008.27 CBY33561.1 - 0.0015 18.8 6.4 0.0028 17.9 6.4 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 CBY33561.1 - 0.0029 18.2 4.1 0.0029 18.2 4.1 2.2 2 0 0 2 2 2 1 Human growth factor-like EGF Laminin_G_2 PF02210.24 CBY33561.1 - 0.012 16.2 0.0 0.043 14.4 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain EGF_2 PF07974.13 CBY33561.1 - 3.5 8.1 12.6 7.2 7.1 12.6 1.5 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.32 CBY33563.1 - 5.7e-11 42.8 16.1 0.015 16.1 0.0 6.8 5 2 2 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY33563.1 - 5.2e-09 36.3 2.4 0.0015 18.8 0.3 5.4 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBY33563.1 - 0.0013 17.9 1.9 1.1 8.2 0.1 3.5 2 1 0 2 2 2 2 Coatomer WD associated region Mcl1_mid PF12341.8 CBY33563.1 - 0.013 14.8 0.3 0.43 9.9 0.1 2.5 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region ComS PF17584.2 CBY33563.1 - 0.033 13.7 0.4 0.1 12.1 0.4 1.8 1 0 0 1 1 1 0 Bacillus competence protein S Tristanin_u2 PF16638.5 CBY33563.1 - 0.12 13.2 0.2 0.48 11.3 0.1 2.1 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Phage_tail_2 PF06199.11 CBY33564.1 - 0.045 13.8 0.1 0.05 13.7 0.1 1.0 1 0 0 1 1 1 0 Phage tail tube protein CBFD_NFYB_HMF PF00808.23 CBY33566.1 - 7.9e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY33566.1 - 3.6e-05 24.1 0.0 5.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY33566.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold AA_permease PF00324.21 CBY33567.1 - 9e-87 291.6 48.2 1.2e-86 291.3 48.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CBY33567.1 - 5.1e-22 78.3 54.8 8.3e-22 77.6 54.8 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CBY33567.1 - 2.3e-13 50.0 0.1 7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Solute carrier family 12 Fez1 PF06818.15 CBY33568.1 - 0.0058 17.1 8.9 0.0072 16.8 8.9 1.1 1 0 0 1 1 1 1 Fez1 Tropomyosin PF00261.20 CBY33568.1 - 0.024 14.0 9.8 0.038 13.4 9.5 1.5 1 1 0 1 1 1 0 Tropomyosin DUF724 PF05266.14 CBY33568.1 - 2 8.2 13.7 0.14 12.0 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 CBY33568.1 - 2.2 8.4 13.1 3.2 7.8 13.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus cwf18 PF08315.12 CBY33569.1 - 1.7e-30 106.4 7.4 2.1e-30 106.1 7.4 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Formyl_trans_N PF00551.19 CBY33570.1 - 3e-15 56.4 0.0 5.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.6 CBY33570.1 - 5.2e-12 45.9 10.4 5.2e-12 45.9 10.4 2.1 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.16 CBY33570.1 - 1.8e-09 37.1 0.3 5.7e-09 35.5 0.1 2.0 2 0 0 2 2 2 1 CUE domain zf-C3HC4_2 PF13923.6 CBY33570.1 - 1.9e-09 37.2 9.1 1.9e-09 37.2 9.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY33570.1 - 2.1e-07 31.1 9.2 1e-06 28.9 9.2 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY33570.1 - 9.9e-07 28.5 7.9 2.9e-06 27.0 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY33570.1 - 1.1e-06 28.3 9.2 1.1e-06 28.3 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY33570.1 - 3.4e-06 27.0 10.1 1.1e-05 25.3 10.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBY33570.1 - 5.3e-05 22.9 5.3 5.3e-05 22.9 5.3 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY33570.1 - 0.00065 19.6 10.9 0.00065 19.6 10.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY33570.1 - 0.00086 19.1 10.2 0.00086 19.1 10.2 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY33570.1 - 0.0014 18.2 12.2 0.0038 16.8 12.2 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CBY33570.1 - 0.013 15.6 8.5 0.037 14.1 8.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBY33570.1 - 0.12 12.5 8.0 0.3 11.3 8.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Formyl_trans_C PF02911.18 CBY33570.1 - 0.14 12.4 0.0 0.48 10.7 0.0 2.0 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain LSM PF01423.22 CBY33571.1 - 7.9e-19 67.1 0.5 9.9e-19 66.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY33571.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Gemin7 PF11095.8 CBY33571.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Transket_pyr PF02779.24 CBY33572.1 - 9.4e-43 145.9 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY33572.1 - 7.9e-34 116.2 0.1 2.1e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Med11 PF10280.9 CBY33574.1 - 2.9e-09 37.5 0.4 3.6e-09 37.2 0.4 1.1 1 0 0 1 1 1 1 Mediator complex protein FANCI_S4 PF14678.6 CBY33574.1 - 0.028 13.5 0.2 0.031 13.4 0.2 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 DUF5446 PF17522.2 CBY33574.1 - 0.078 13.2 0.7 0.2 11.8 0.4 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5446) DHR10 PF18595.1 CBY33574.1 - 0.13 12.4 1.7 0.19 11.8 1.5 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain ParD_like PF11903.8 CBY33577.1 - 0.0098 15.9 0.8 0.014 15.5 0.8 1.4 1 1 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system Dimer_Tnp_hAT PF05699.14 CBY33578.1 - 3.1e-08 33.3 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Galactosyl_T PF01762.21 CBY33579.1 - 8.1e-14 51.9 0.2 1.1e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 Galactosyltransferase HNF-1A_C PF04813.12 CBY33579.1 - 0.03 15.1 0.3 0.57 11.0 0.2 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus CH PF00307.31 CBY33580.1 - 3e-15 56.3 0.0 6e-15 55.4 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 CBY33580.1 - 3e-14 52.3 4.9 3e-14 52.3 4.9 2.1 3 0 0 3 3 3 1 Calponin family repeat CDC24 PF06395.11 CBY33580.1 - 0.17 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin BTB_2 PF02214.22 CBY33581.1 - 1.9e-15 56.9 0.1 3.4e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY33581.1 - 0.0045 17.2 0.1 0.0097 16.1 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain AAA_33 PF13671.6 CBY33582.1 - 9.9e-07 29.0 0.1 9.9e-07 29.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain YflT PF11181.8 CBY33582.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT Trypan_PARP PF05887.11 CBY33583.1 - 0.00034 20.6 39.1 0.00034 20.6 39.1 2.0 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 CBY33583.1 - 8.6 5.4 25.6 1.8e+04 -8.0 25.3 2.5 1 1 0 1 1 1 0 Sperm equatorial segment protein 1 LMBR1 PF04791.16 CBY33584.1 - 3.8e-149 497.9 15.8 4.9e-149 497.5 15.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Orthoreo_P10 PF07204.11 CBY33584.1 - 0.2 11.6 2.3 24 4.9 0.0 3.4 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 RWD PF05773.22 CBY33585.1 - 4.2e-14 52.8 3.4 4.2e-14 52.8 3.4 1.8 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CBY33585.1 - 1.1e-05 25.8 6.6 4.3e-05 23.9 6.6 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Trm112p PF03966.16 CBY33586.1 - 3.3e-14 53.2 0.0 3.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF1002 PF06207.11 CBY33587.1 - 0.0011 18.5 0.5 0.0011 18.5 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1002) IMUP PF15761.5 CBY33587.1 - 0.043 14.5 4.7 0.043 14.5 4.7 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein HTH_32 PF13565.6 CBY33587.1 - 0.19 12.3 0.7 5.9 7.6 0.1 2.6 1 1 2 3 3 3 0 Homeodomain-like domain DEAD PF00270.29 CBY33588.1 - 6.6e-39 133.5 1.5 8.8e-39 133.1 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY33588.1 - 3.4e-32 111.1 0.4 1.1e-31 109.4 0.2 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY33588.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBY33588.1 - 0.048 14.0 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.25 CBY33588.1 - 0.056 12.7 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 CBY33588.1 - 0.16 12.3 0.9 1.4 9.2 0.9 2.4 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 CBY33588.1 - 0.18 11.1 0.0 0.18 11.1 0.0 2.9 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.22 CBY33589.1 - 4.5e-17 61.5 0.1 6.7e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 CBY33589.1 - 0.11 13.2 28.4 0.17 12.6 28.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family Adeno_E3A PF05248.12 CBY33589.1 - 0.14 12.2 0.0 19 5.4 0.0 2.1 1 1 1 2 2 2 0 Adenovirus E3A RNA_pol_N PF01194.17 CBY33592.1 - 2.6e-34 117.3 0.3 2.9e-34 117.1 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CBY33592.1 - 0.012 15.8 0.2 0.017 15.3 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ank_2 PF12796.7 CBY33594.1 - 9.8e-24 83.8 0.1 1.7e-15 57.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY33594.1 - 1e-16 61.0 0.1 7.8e-11 42.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33594.1 - 4e-13 48.2 0.1 7.1e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SH3_9 PF14604.6 CBY33594.1 - 9.7e-13 47.8 0.4 2.1e-12 46.7 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank PF00023.30 CBY33594.1 - 1e-12 47.9 0.1 2.2e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY33594.1 - 1.9e-12 47.1 0.6 7.2e-07 29.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SH3_1 PF00018.28 CBY33594.1 - 9.4e-12 44.4 0.6 2e-11 43.3 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY33594.1 - 1.2e-10 40.9 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Fib_alpha PF08702.10 CBY33594.1 - 9.7 6.4 21.5 0.58 10.3 6.7 3.0 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CSD PF00313.22 CBY33595.1 - 1.6e-21 75.9 0.4 2.8e-21 75.1 0.4 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain KdpC PF02669.15 CBY33595.1 - 0.011 15.5 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 K+-transporting ATPase, c chain OB_RNB PF08206.11 CBY33595.1 - 0.044 13.5 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain Rrn6 PF10214.9 CBY33595.1 - 0.17 10.3 3.1 0.24 9.9 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SET PF00856.28 CBY33596.1 - 1.7e-19 70.8 0.5 1.7e-19 70.8 0.5 3.2 3 1 0 3 3 3 1 SET domain preSET_CXC PF18264.1 CBY33596.1 - 5.5e-11 42.7 15.9 5.5e-11 42.7 15.9 3.7 3 1 0 3 3 3 1 CXC domain PRC2_HTH_1 PF18118.1 CBY33596.1 - 0.001 19.9 0.9 0.001 19.9 0.9 2.6 2 1 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain Myb_DNA-binding PF00249.31 CBY33596.1 - 0.017 15.3 0.6 0.66 10.2 0.0 3.4 4 0 0 4 4 4 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY33596.1 - 0.095 13.0 3.7 9.6 6.5 0.0 3.7 4 0 0 4 4 4 0 Myb-like DNA-binding domain E2F_CC-MB PF16421.5 CBY33600.1 - 1.5e-24 86.1 0.0 3.9e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 CBY33600.1 - 4.2e-22 78.0 0.0 8.9e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 CBY33600.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TMEM18 PF14770.6 CBY33601.1 - 4e-23 81.7 3.0 4.5e-23 81.5 3.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 SecIII_SopE_N PF05364.14 CBY33602.1 - 0.16 12.0 1.1 9.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus Myosin_head PF00063.21 CBY33603.1 - 1.8e-265 882.4 0.0 1.8e-265 882.4 0.0 3.5 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY33603.1 - 6.5e-57 193.2 229.9 8.4e-57 192.8 229.9 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY33603.1 - 5.6e-05 22.9 0.9 0.00017 21.4 0.9 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBY33603.1 - 0.11 12.7 0.0 0.11 12.7 0.0 4.5 5 0 0 5 5 5 0 AAA domain DUF4198 PF10670.9 CBY33603.1 - 0.13 12.7 2.1 3.2 8.1 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Sulfatase PF00884.23 CBY33605.1 - 7.8e-60 202.9 0.2 9.7e-60 202.5 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY33605.1 - 1.9e-06 27.7 0.1 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY33605.1 - 3.9e-05 22.5 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 CBY33605.1 - 4.3e-05 23.7 0.1 0.12 12.6 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) PMP22_Claudin PF00822.20 CBY33606.1 - 4.3e-17 62.5 2.3 5.3e-17 62.2 2.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY33606.1 - 1.2e-10 41.4 0.6 3.6e-10 39.9 0.6 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 CBY33606.1 - 4.9e-05 23.6 0.8 7.7e-05 23.0 0.8 1.4 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF4064 PF13273.6 CBY33606.1 - 0.013 15.8 7.8 0.013 15.8 7.8 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Clc-like PF07062.12 CBY33606.1 - 0.015 14.8 0.6 0.038 13.5 0.0 1.9 1 1 0 2 2 2 0 Clc-like GIDE PF12483.8 CBY33606.1 - 0.04 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase Amastin PF07344.11 CBY33606.1 - 0.041 13.7 0.5 0.11 12.3 0.4 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein SUR7 PF06687.12 CBY33606.1 - 0.12 12.0 1.2 3.3 7.3 1.2 2.2 1 1 0 1 1 1 0 SUR7/PalI family Claudin_3 PF06653.11 CBY33606.1 - 0.18 11.8 5.1 1.5 8.8 4.7 2.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Tetraspanin PF00335.20 CBY33606.1 - 1.1 9.0 8.4 0.69 9.6 0.5 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF973 PF06157.11 CBY33606.1 - 2.8 6.9 10.2 11 5.0 10.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Trypan_PARP PF05887.11 CBY33607.1 - 0.00024 21.1 17.1 0.00042 20.3 17.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GKAP PF03359.13 CBY33607.1 - 0.032 13.8 4.3 0.048 13.2 4.3 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Presenilin PF01080.17 CBY33607.1 - 0.15 10.8 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 CBY33607.1 - 0.34 11.0 1.4 0.51 10.4 1.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Ndc1_Nup PF09531.10 CBY33607.1 - 1.2 7.8 5.0 1.5 7.4 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1126 PF06565.12 CBY33608.1 - 1.2e-79 262.9 0.5 6.7e-30 103.0 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain DUF1126 PF06565.12 CBY33609.1 - 3.5e-32 110.4 0.2 2.2e-24 85.3 0.0 2.2 2 0 0 2 2 2 2 DUF1126 PH-like domain Kazal_2 PF07648.15 CBY33610.1 - 3.2e-26 91.2 115.6 5.8e-09 35.9 6.4 9.7 9 0 0 9 9 9 5 Kazal-type serine protease inhibitor domain Laminin_G_2 PF02210.24 CBY33610.1 - 9.4e-16 58.5 0.0 2.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Kazal_1 PF00050.21 CBY33610.1 - 3e-15 55.9 81.2 5.3e-07 29.5 11.6 6.8 6 0 0 6 6 6 5 Kazal-type serine protease inhibitor domain Laminin_G_1 PF00054.23 CBY33610.1 - 4e-14 52.9 0.0 6.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_EGF PF00053.24 CBY33610.1 - 3.9e-05 23.7 35.0 0.00019 21.5 15.1 10.5 8 4 3 11 11 11 2 Laminin EGF domain Laminin_G_2 PF02210.24 CBY33611.1 - 6.1e-15 55.9 0.8 8.8e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 Laminin G domain Laminin_G_1 PF00054.23 CBY33611.1 - 1.5e-06 28.4 0.0 0.014 15.6 0.0 2.5 2 1 0 2 2 2 2 Laminin G domain Laminin_G_3 PF13385.6 CBY33611.1 - 0.00036 20.7 0.0 0.00058 20.0 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Receptor_IA-2 PF11548.8 CBY33611.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 GST_N PF02798.20 CBY33613.1 - 1.9e-07 31.3 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY33613.1 - 0.003 17.9 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CBY33613.1 - 0.0036 18.0 0.0 0.0068 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CBY33613.1 - 0.031 14.6 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Na_Ca_ex PF01699.24 CBY33614.1 - 5.7e-26 91.3 25.6 1.1e-19 70.9 10.0 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PI3K_1B_p101 PF10486.9 CBY33614.1 - 0.14 9.9 0.0 0.2 9.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SSF PF00474.17 CBY33616.1 - 4.8e-34 117.9 30.0 6e-34 117.6 30.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Sulfotransfer_1 PF00685.27 CBY33618.1 - 0.00018 21.1 0.1 0.00019 21.0 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Mito_carr PF00153.27 CBY33619.1 - 1.6e-11 44.0 5.4 1.5e-05 24.8 0.2 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF3791 PF12668.7 CBY33619.1 - 0.016 15.2 0.3 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Kri1_C PF12936.7 CBY33621.1 - 1.2e-15 57.5 0.8 1.2e-15 57.5 0.8 5.0 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 CBY33621.1 - 0.0047 17.5 23.1 0.0047 17.5 23.1 4.4 1 1 2 3 3 3 1 KRI1-like family GAGA_bind PF06217.12 CBY33621.1 - 1.4 9.2 20.5 1.9 8.7 7.7 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family NAD_binding_3 PF03447.16 CBY33622.1 - 1e-06 29.4 0.1 1.5e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.18 CBY33624.1 - 8.1e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 Evf PF18270.1 CBY33624.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Virulence factor Evf zf-H2C2_2 PF13465.6 CBY33627.1 - 1.4e-19 69.5 44.8 5.6e-08 32.9 4.8 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY33627.1 - 5.4e-17 61.2 43.1 6.9e-06 26.2 1.9 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY33627.1 - 9.6e-11 41.6 41.4 0.00071 20.2 1.5 5.4 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY33627.1 - 1.4e-09 38.0 29.3 0.058 13.7 1.0 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY33627.1 - 7.6e-07 29.3 31.1 0.11 12.9 0.4 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CBY33627.1 - 0.049 14.1 29.7 0.43 11.0 0.2 5.7 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2180 PF09947.9 CBY33627.1 - 0.058 13.4 0.5 0.058 13.4 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.7 CBY33627.1 - 0.15 12.4 27.8 4.5 7.7 0.7 5.2 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) PHF5 PF03660.14 CBY33627.1 - 1.2 9.4 8.0 0.94 9.7 3.5 2.5 2 1 1 3 3 3 0 PHF5-like protein zf-C2H2_6 PF13912.6 CBY33627.1 - 1.4 9.0 40.6 0.29 11.2 3.3 5.5 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY33628.1 - 2.8e-06 27.5 7.6 0.0086 16.3 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY33628.1 - 0.00061 20.1 2.8 0.077 13.3 0.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY33628.1 - 0.0053 17.1 7.6 0.69 10.4 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY33628.1 - 0.051 14.4 12.9 0.23 12.4 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger OrsD PF12013.8 CBY33628.1 - 0.06 13.8 4.3 0.91 10.0 0.1 3.1 2 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met2 PF12907.7 CBY33628.1 - 0.37 11.0 2.9 4.2 7.6 0.0 3.2 3 0 0 3 3 3 0 Zinc-binding Atx10homo_assoc PF09759.9 CBY33629.1 - 0.03 14.3 0.1 0.15 12.1 0.1 2.3 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain PPV_E1_N PF00524.18 CBY33629.1 - 0.18 12.2 1.5 2.3 8.7 0.2 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.32 CBY33630.1 - 2.6e-36 123.0 17.3 7.5e-09 36.1 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CBY33630.1 - 4.2e-33 114.3 2.1 7.2e-33 113.6 2.1 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CBY33630.1 - 3.6e-12 46.4 0.1 4.6e-05 23.6 0.0 4.3 2 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY33630.1 - 0.0042 17.0 0.0 0.087 12.7 0.0 2.6 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A PARP PF00644.20 CBY33631.1 - 0.0012 18.5 0.0 0.0044 16.6 0.0 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain MBOAT PF03062.19 CBY33632.1 - 2.4e-11 43.6 18.7 9.3e-10 38.4 11.2 3.4 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ARTD15_N PF18084.1 CBY33632.1 - 2.1e-08 34.3 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain Mago_nashi PF02792.14 CBY33633.1 - 1.6e-77 258.5 0.2 1.8e-77 258.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DCP2 PF05026.13 CBY33635.1 - 7.2e-26 90.3 2.5 7.5e-26 90.3 0.6 2.0 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 CBY33635.1 - 1.6e-17 63.8 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MARVEL PF01284.23 CBY33636.1 - 4.7e-06 26.7 10.9 6.1e-06 26.3 10.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain Ribosomal_L27A PF00828.19 CBY33637.1 - 3.2e-09 37.5 0.0 5.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4953 PF16313.5 CBY33638.1 - 0.04 13.1 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Met-zincin IBR PF01485.21 CBY33639.1 - 3.8e-15 55.9 27.7 2.2e-09 37.4 5.4 4.9 4 2 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CBY33639.1 - 0.0011 18.8 7.6 0.0011 18.8 7.6 5.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY33639.1 - 0.0015 18.4 9.8 0.0015 18.4 9.8 5.2 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Vps39_1 PF10366.9 CBY33639.1 - 0.014 15.7 1.8 0.05 13.9 0.1 2.6 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.6 CBY33639.1 - 0.027 14.8 12.8 0.027 14.8 12.8 4.8 3 2 1 4 4 4 0 Ring finger domain zf-RING_11 PF17123.5 CBY33639.1 - 2.7 7.8 13.7 0.14 12.0 5.5 3.2 3 0 0 3 3 3 0 RING-like zinc finger JAB PF01398.21 CBY33640.1 - 6.7e-29 100.3 0.2 1.3e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CBY33640.1 - 7.8e-14 52.4 0.2 1.8e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CBY33640.1 - 0.00026 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CBY33640.1 - 0.0078 16.3 0.2 0.016 15.2 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF4471 PF14740.6 CBY33641.1 - 3.5e-60 203.8 2.5 4.2e-60 203.6 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4471 PF14740.6 CBY33642.1 - 2.7e-15 56.4 1.1 2.9e-15 56.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) SHR-BD PF06650.12 CBY33643.1 - 5.7e-61 206.3 0.5 4.1e-56 190.3 0.0 3.2 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CBY33643.1 - 2.8e-15 56.6 2.3 3.4e-09 36.7 0.0 3.9 3 1 1 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal XPA_N PF01286.18 CBY33644.1 - 4e-08 33.1 7.1 5.9e-08 32.6 7.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal XPA_C PF05181.12 CBY33644.1 - 0.0028 17.6 0.1 0.0058 16.6 0.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus ZZ PF00569.17 CBY33644.1 - 2 8.3 7.6 1.7 8.5 1.6 2.3 1 1 1 2 2 2 0 Zinc finger, ZZ type Vac14_Fig4_bd PF11916.8 CBY33645.1 - 1.3e-50 171.5 0.8 2.7e-50 170.5 0.8 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.7 CBY33645.1 - 0.0039 17.3 0.7 0.12 12.4 0.1 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF4485 PF14846.6 CBY33645.1 - 0.017 15.2 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) HEAT PF02985.22 CBY33645.1 - 0.031 14.5 0.1 9.7 6.8 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat MARVEL PF01284.23 CBY33646.1 - 1e-10 41.8 13.5 2.6e-10 40.5 13.5 1.7 1 1 0 1 1 1 1 Membrane-associating domain TMEM213 PF15192.6 CBY33646.1 - 0.37 10.8 1.4 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 TMEM213 family DUF4173 PF13777.6 CBY33646.1 - 0.59 9.5 8.8 0.014 14.9 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF1218 PF06749.12 CBY33646.1 - 8.1 7.0 14.6 59 4.3 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) LRR_4 PF12799.7 CBY33647.1 - 3.1e-19 68.7 11.9 9.3e-07 29.1 2.7 4.5 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY33647.1 - 2.8e-13 49.4 9.2 2.3e-06 27.3 0.8 3.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 CBY33647.1 - 2.7e-05 24.1 9.5 1.9 9.4 0.2 6.6 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY33647.1 - 0.11 12.6 12.7 13 6.2 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Trypsin PF00089.26 CBY33651.1 - 5.7e-44 150.5 3.8 6.4e-44 150.4 3.8 1.0 1 0 0 1 1 1 1 Trypsin SDF PF00375.18 CBY33652.1 - 3.1e-47 161.5 7.9 3.5e-47 161.3 7.9 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family fn3 PF00041.21 CBY33653.1 - 7.8e-72 237.7 17.1 7.6e-15 55.0 0.1 10.7 10 0 0 10 10 10 10 Fibronectin type III domain LCCL PF03815.19 CBY33653.1 - 9.5e-20 70.5 1.2 4.3e-19 68.4 0.8 2.3 2 0 0 2 2 2 1 LCCL domain DUF4992 PF16383.5 CBY33653.1 - 6.8e-15 55.1 14.2 5.2e-05 22.9 0.1 8.2 6 3 2 9 9 9 3 Domain of unknown function Pur_ac_phosph_N PF16656.5 CBY33653.1 - 3.2e-13 50.1 35.5 0.021 15.4 0.0 11.6 9 4 0 9 9 9 4 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY33653.1 - 7.3e-10 39.1 0.0 8.2 6.8 0.0 7.9 9 0 0 9 9 8 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 CBY33653.1 - 7.5e-10 39.1 1.5 0.58 10.6 0.0 7.4 8 0 0 8 8 8 2 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 CBY33653.1 - 1.2e-09 38.1 0.0 0.094 12.9 0.0 7.6 9 0 0 9 9 9 2 Fibronectin type III domain Arylsulfotran_N PF17425.2 CBY33653.1 - 0.00023 21.2 4.0 25 5.0 0.0 6.2 6 1 1 7 7 7 0 Arylsulfotransferase Ig-like domain fn3_4 PF16794.5 CBY33653.1 - 0.0045 16.9 0.6 5.9 6.9 0.0 5.7 5 1 0 5 5 5 1 Fibronectin-III type domain Rxt3 PF08642.10 CBY33653.1 - 0.0071 17.1 0.4 0.47 11.2 0.2 2.6 1 1 1 2 2 2 1 Histone deacetylation protein Rxt3 Big_4 PF07532.11 CBY33653.1 - 0.061 13.1 3.2 8.2 6.3 0.2 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 4) MR_MLE_N PF02746.16 CBY33653.1 - 0.1 12.8 0.6 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1410 PF07198.11 CBY33653.1 - 0.32 11.5 5.0 1.1e+02 3.4 0.0 4.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1410) PAN_3 PF08277.12 CBY33654.1 - 0.024 14.5 4.4 0.074 12.9 4.4 1.9 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 CBY33654.1 - 0.12 12.4 7.3 0.042 13.8 4.4 1.8 2 0 0 2 2 2 0 PAN domain SBF PF01758.16 CBY33655.1 - 0.005 16.5 2.4 0.005 16.5 2.4 2.3 1 1 1 2 2 2 1 Sodium Bile acid symporter family DUF4834 PF16118.5 CBY33655.1 - 0.93 10.5 0.0 0.93 10.5 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF1192 PF06698.11 CBY33656.1 - 1.8 8.7 6.1 3.8 7.7 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AP3D1 PF06375.11 CBY33657.1 - 0.003 17.8 1.1 0.004 17.4 1.1 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Sof1 PF04158.14 CBY33657.1 - 2.8 8.3 10.1 1.9 8.8 5.0 2.2 1 1 1 2 2 2 0 Sof1-like domain MIEAP PF16026.5 CBY33658.1 - 1.4e-48 165.7 0.1 1.4e-48 165.7 0.1 2.5 3 0 0 3 3 3 1 Mitochondria-eating protein Arm_APC_u3 PF16629.5 CBY33658.1 - 0.017 14.7 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Armadillo-associated region on APC DUF812 PF05667.11 CBY33658.1 - 0.14 11.0 15.7 0.35 9.7 15.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Herpes_LP PF03363.13 CBY33658.1 - 0.78 9.5 4.4 4.6 7.0 2.1 2.5 2 0 0 2 2 2 0 Herpesvirus leader protein Prominin PF05478.11 CBY33658.1 - 1 7.2 5.6 1.7 6.5 5.6 1.2 1 0 0 1 1 1 0 Prominin Lipoprotein_20 PF13942.6 CBY33658.1 - 3.4 7.6 9.9 7.8 6.4 9.9 1.5 1 0 0 1 1 1 0 YfhG lipoprotein ATG16 PF08614.11 CBY33658.1 - 3.4 7.9 22.7 11 6.2 22.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CBY33658.1 - 6.6 6.2 11.7 49 3.4 13.1 1.9 2 1 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_M10 PF00413.24 CBY33659.1 - 2.5e-51 173.6 0.1 4.4e-51 172.9 0.1 1.4 1 0 0 1 1 1 1 Matrixin Hemopexin PF00045.19 CBY33659.1 - 1.9e-19 69.3 8.9 2.7e-09 36.8 0.0 3.9 3 0 0 3 3 3 3 Hemopexin PG_binding_1 PF01471.18 CBY33659.1 - 0.00075 19.7 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Peptidase_M54 PF07998.11 CBY33659.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M66 PF10462.9 CBY33659.1 - 0.026 13.5 0.4 0.048 12.6 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CBY33659.1 - 0.061 11.9 0.2 0.1 11.2 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family CTP_transf_like PF01467.26 CBY33660.1 - 3e-23 82.6 0.4 2.2e-22 79.8 0.1 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like DDE_Tnp_1_4 PF13701.6 CBY33660.1 - 0.16 10.2 0.1 0.22 9.7 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Kunitz_BPTI PF00014.23 CBY33661.1 - 4.5e-22 78.0 5.9 5.3e-22 77.8 5.9 1.1 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain Fungus-induced PF10917.8 CBY33661.1 - 0.1 12.9 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Fungus-induced protein Zona_pellucida PF00100.23 CBY33662.1 - 8.5e-25 88.0 0.9 9.7e-25 87.8 0.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Metallophos PF00149.28 CBY33663.1 - 9.1e-17 62.2 0.9 1.4e-16 61.6 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Phage_integrase PF00589.22 CBY33663.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family T4BSS_DotI_IcmL PF11393.8 CBY33663.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component DUF4743 PF15916.5 CBY33664.1 - 2.6e-06 27.4 0.0 5.9e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CBY33664.1 - 0.00066 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Rsa3 PF14615.6 CBY33666.1 - 0.11 12.0 1.0 0.28 10.8 1.0 1.6 1 1 0 1 1 1 0 Ribosome-assembly protein 3 EMP24_GP25L PF01105.24 CBY33668.1 - 4e-35 121.4 0.1 4.5e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CBY33668.1 - 0.0026 18.0 0.1 0.0035 17.6 0.1 1.4 1 0 0 1 1 1 1 SdrD B-like domain DUF4198 PF10670.9 CBY33668.1 - 0.03 14.7 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Pkinase PF00069.25 CBY33669.1 - 6.7e-54 183.0 0.0 8.9e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33669.1 - 1.9e-37 128.9 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33669.1 - 0.00076 18.9 0.1 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Mrx7 PF10906.8 CBY33669.1 - 0.12 12.6 0.1 0.35 11.2 0.1 1.9 1 1 0 1 1 1 0 MIOREX complex component 7 Gemini_AL1 PF00799.20 CBY33671.1 - 0.099 13.0 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain VPS53_C PF16854.5 CBY33672.1 - 0.015 15.2 1.4 0.018 14.9 1.4 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Dysbindin PF04440.16 CBY33672.1 - 0.11 12.7 0.4 0.14 12.4 0.4 1.1 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) SWIRM-assoc_2 PF16496.5 CBY33673.1 - 0.2 10.5 0.0 0.21 10.4 0.0 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF2892 PF11127.8 CBY33673.1 - 1.4 9.0 5.3 5.4 7.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF3040 PF11239.8 CBY33673.1 - 4.7 7.5 6.7 51 4.2 6.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Guanylate_cyc PF00211.20 CBY33674.1 - 3.7e-44 150.5 0.0 6.7e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Tox-MPTase2 PF15638.6 CBY33674.1 - 0.067 12.9 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase_Tyr PF07714.17 CBY33674.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glutaminase PF04960.15 CBY33675.1 - 3.6e-117 390.6 0.0 4.4e-117 390.3 0.0 1.1 1 0 0 1 1 1 1 Glutaminase EF-hand_14 PF17959.1 CBY33675.1 - 5.1e-14 52.4 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Ank_2 PF12796.7 CBY33675.1 - 1.5e-05 25.5 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY33675.1 - 0.0016 18.8 0.0 0.01 16.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CBY33675.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY33675.1 - 0.086 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat DUF3718 PF12514.8 CBY33675.1 - 0.1 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) RNA_pol_Rpb1_5 PF04998.17 CBY33677.1 - 4.5e-85 285.3 0.4 7e-85 284.7 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBY33677.1 - 5.2e-63 212.2 2.0 1.4e-61 207.6 2.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CBY33677.1 - 3.7e-57 194.0 2.4 5.5e-55 186.9 0.2 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CBY33677.1 - 6.3e-38 130.2 0.0 1.7e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBY33677.1 - 1.9e-31 108.2 0.0 6e-31 106.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 PYNP_C PF07831.13 CBY33677.1 - 0.052 13.2 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain SpoIIM PF01944.17 CBY33678.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Stage II sporulation protein M DUF2968 PF11180.8 CBY33678.1 - 0.13 11.9 15.0 2.4 7.7 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Csm1_N PF18504.1 CBY33678.1 - 0.14 12.5 24.0 1.1 9.6 4.8 3.9 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF641 PF04859.12 CBY33678.1 - 0.63 10.4 26.7 1.3 9.4 1.7 3.6 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) ATG16 PF08614.11 CBY33678.1 - 3.2 7.9 18.1 1.4e+02 2.6 18.0 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Chromo PF00385.24 CBY33679.1 - 2.6e-15 56.1 3.3 4.2e-15 55.4 1.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PFU PF09070.11 CBY33679.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) HATPase_c_5 PF14501.6 CBY33679.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 GHKL domain Ribosomal_S14 PF00253.21 CBY33680.1 - 1.4e-10 40.8 2.5 1.6e-10 40.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PC4 PF02229.16 CBY33681.1 - 2.2e-35 120.0 4.7 8.4e-19 66.9 0.9 2.4 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) CDC45 PF02724.14 CBY33681.1 - 2.5 6.3 5.8 2.9 6.1 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CBY33681.1 - 3.4 6.3 3.5 3.8 6.2 3.5 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 CBY33682.1 - 1.7e-36 126.0 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33682.1 - 5.8e-06 25.8 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY33682.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY33682.1 - 0.0003 20.2 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY33682.1 - 0.0024 16.7 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY33682.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pentapeptide_4 PF13599.6 CBY33683.1 - 2.6e-11 43.5 15.1 5.5e-07 29.7 3.7 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Sugar_tr PF00083.24 CBY33683.1 - 5e-06 25.6 0.4 0.0046 15.9 0.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Pentapeptide_3 PF13576.6 CBY33683.1 - 0.026 14.7 3.5 0.026 14.7 3.5 3.3 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.16 CBY33683.1 - 0.041 12.8 8.4 0.16 10.9 8.4 1.7 2 0 0 2 2 2 0 Major Facilitator Superfamily Pentapeptide PF00805.22 CBY33683.1 - 0.077 12.7 0.2 0.37 10.5 0.0 2.2 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) hGDE_N PF14699.6 CBY33683.1 - 0.19 11.9 1.2 2 8.6 0.0 2.5 1 1 1 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme AA_permease PF00324.21 CBY33684.1 - 1.2e-53 182.4 43.9 3.8e-34 118.1 11.7 2.1 2 0 0 2 2 2 2 Amino acid permease SLC12 PF03522.15 CBY33684.1 - 6.5e-28 97.9 0.1 2.7e-21 76.1 0.1 2.8 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease_2 PF13520.6 CBY33684.1 - 6e-16 58.3 13.4 6e-16 58.3 13.4 2.2 2 0 0 2 2 2 1 Amino acid permease DUF3048_C PF17479.2 CBY33684.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain LRR_8 PF13855.6 CBY33686.1 - 2.1e-38 129.9 17.5 4.6e-15 55.1 2.2 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY33686.1 - 8.6e-16 57.8 12.7 1.1e-06 28.9 2.3 5.4 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY33686.1 - 7.5e-11 42.1 0.1 5.3e-10 39.4 0.0 2.3 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY33686.1 - 2.2e-08 33.8 3.8 1.2e-05 24.9 0.4 2.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY33686.1 - 2.7e-07 30.2 14.9 0.0086 16.5 0.5 6.8 7 0 0 7 7 7 2 Leucine Rich Repeat CBP_BcsR PF10945.8 CBY33686.1 - 0.056 12.9 0.2 5.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR LRR_6 PF13516.6 CBY33686.1 - 0.13 12.4 16.0 0.48 10.6 0.3 5.6 6 0 0 6 6 6 0 Leucine Rich repeat Tachykinin PF02202.16 CBY33686.1 - 0.27 11.2 0.7 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Tachykinin family Glyco_hydro_47 PF01532.20 CBY33688.1 - 3.5e-147 491.0 2.9 4.6e-147 490.6 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FapA PF03961.13 CBY33688.1 - 0.24 10.0 2.1 0.35 9.4 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1003 PF06210.11 CBY33688.1 - 0.25 11.4 0.7 0.55 10.4 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) RPN1_RPN2_N PF17781.1 CBY33690.1 - 1.5e-108 362.9 0.0 1.5e-108 362.9 0.0 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CBY33690.1 - 5.1e-29 99.2 21.3 1.2e-08 34.9 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBY33690.1 - 4.9e-05 23.6 0.4 0.51 10.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats Zip PF02535.22 CBY33690.1 - 0.041 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 CBY33690.1 - 0.096 12.4 0.7 0.2 11.4 0.7 1.4 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 CBY33690.1 - 0.19 11.5 2.7 0.41 10.4 2.7 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF262 PF03235.14 CBY33690.1 - 0.83 9.8 3.7 30 4.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF262 Ferlin_C PF16165.5 CBY33690.1 - 2.2 8.2 6.8 4.9 7.1 6.8 1.5 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 CBY33690.1 - 4.5 5.4 6.3 0.26 9.5 1.0 1.5 2 0 0 2 2 2 0 CDC45-like protein MCM PF00493.23 CBY33691.1 - 1.1e-94 315.7 0.0 1.7e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY33691.1 - 2.2e-36 124.5 0.1 4.3e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY33691.1 - 1.2e-26 93.0 1.2 6.5e-25 87.4 0.5 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CBY33691.1 - 1.4e-14 54.5 1.2 1.4e-14 54.5 1.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY33691.1 - 1.5e-08 34.3 0.1 9.5e-06 25.1 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY33691.1 - 9.6e-08 32.1 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY33691.1 - 7.1e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CBY33691.1 - 0.09 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-DNA_Pol PF08996.10 CBY33692.1 - 5.4e-16 58.9 1.9 7.5e-16 58.4 1.0 1.6 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B PF00136.21 CBY33692.1 - 3.7e-08 32.5 0.0 5.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B PF00136.21 CBY33693.1 - 2.7e-87 293.4 3.2 4.8e-85 286.0 3.2 2.1 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY33693.1 - 2.1e-17 63.3 0.0 7.2e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CBY33693.1 - 0.0082 15.1 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral MCM_OB PF17207.3 CBY33694.1 - 2.6e-36 124.3 0.1 5.1e-36 123.3 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM PF00493.23 CBY33694.1 - 1.5e-29 102.7 0.0 2.5e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_N PF14551.6 CBY33694.1 - 7.9e-15 55.3 1.2 1.7e-14 54.3 1.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain DNA_pol_B PF00136.21 CBY33695.1 - 8.1e-111 370.9 0.2 1.7e-110 369.9 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY33695.1 - 8.1e-38 130.4 0.0 2.5e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CBY33695.1 - 3.9e-15 56.1 1.3 1e-14 54.7 1.3 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.8 CBY33695.1 - 5.8e-08 32.7 10.5 5.9e-08 32.7 6.5 3.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Pkinase PF00069.25 CBY33696.1 - 2.2e-76 256.7 0.2 6.9e-37 127.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33696.1 - 3.9e-55 186.9 0.0 1.2e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY33696.1 - 3.7e-26 92.1 0.0 1.8e-11 43.9 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CBY33696.1 - 1.9e-06 26.9 4.5 0.1 11.3 0.0 4.3 5 0 0 5 5 5 2 Fungal protein kinase FAD_binding_8 PF08022.12 CBY33696.1 - 1.8e-05 24.8 0.0 0.041 14.0 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain Kdo PF06293.14 CBY33696.1 - 0.00013 21.4 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBY33696.1 - 0.00088 18.8 0.2 2.5 7.5 0.0 3.1 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL APH PF01636.23 CBY33696.1 - 0.0013 18.7 0.0 3.4 7.5 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family NMD3 PF04981.13 CBY33696.1 - 0.0045 16.5 3.9 1.1 8.7 0.4 2.4 2 0 0 2 2 2 2 NMD3 family DUF2015 PF09435.10 CBY33696.1 - 0.0051 16.7 0.8 4.7 7.1 0.1 2.7 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF2015) Arteri_nsp7a PF16749.5 CBY33696.1 - 0.0085 16.3 0.3 3.6 7.8 0.0 2.6 2 0 0 2 2 2 1 Arterivirus nonstructural protein 7 alpha BHD_1 PF10403.9 CBY33696.1 - 0.047 13.5 0.1 2.2e+02 1.8 0.0 4.4 4 0 0 4 4 4 0 Rad4 beta-hairpin domain 1 MazG_C PF18722.1 CBY33696.1 - 0.098 12.2 1.6 12 5.4 0.1 2.6 3 0 0 3 3 3 0 MazG C-terminal domain DUF2645 PF10840.8 CBY33696.1 - 0.13 12.9 0.5 4.5 8.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) DUF4499 PF14934.6 CBY33697.1 - 2.9e-12 46.8 0.2 4.9e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) TSP_1 PF00090.19 CBY33698.1 - 8.4e-17 61.1 59.7 8.5e-09 35.5 7.0 5.1 5 2 0 5 5 5 3 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY33699.1 - 6.2e-55 183.2 186.9 8.3e-07 29.1 4.0 16.2 14 3 1 15 15 15 15 Thrombospondin type 1 domain DUF4499 PF14934.6 CBY33700.1 - 0.00022 21.5 3.5 0.00025 21.3 2.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) Sulfotransfer_2 PF03567.14 CBY33701.1 - 1e-32 114.0 0.0 1.2e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase family CdiI_2 PF18593.1 CBY33701.1 - 0.14 12.8 0.1 0.37 11.5 0.1 1.7 1 0 0 1 1 1 0 CdiI immunity protein Ammonium_transp PF00909.21 CBY33702.1 - 3.4e-94 315.8 19.8 4.1e-94 315.5 19.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family An_peroxidase PF03098.15 CBY33703.1 - 7.8e-59 199.6 0.0 1e-58 199.3 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase COX4_pro PF03626.14 CBY33704.1 - 0.021 15.3 2.5 1.9 8.9 1.2 2.4 2 1 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Ni_hydr_CYTB PF01292.20 CBY33704.1 - 0.039 13.5 0.3 0.053 13.1 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 RRM_1 PF00076.22 CBY33705.1 - 1.5e-17 63.1 0.1 2.2e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1797 PF08796.10 CBY33705.1 - 0.11 12.6 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) OB_RNB PF08206.11 CBY33705.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain EGF_CA PF07645.15 CBY33706.1 - 1.5e-187 607.7 705.6 8.9e-09 35.4 12.0 49.9 44 7 4 48 48 48 36 Calcium-binding EGF domain cEGF PF12662.7 CBY33706.1 - 2.3e-73 241.6 424.5 6.8e-05 22.7 3.3 46.4 45 1 0 45 45 45 33 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY33706.1 - 1.3e-61 204.5 614.9 5.8e-08 32.8 8.0 49.1 48 4 3 51 51 51 32 EGF domain EGF PF00008.27 CBY33706.1 - 3.6e-15 55.9 529.4 0.00011 22.4 6.8 45.7 44 1 1 45 45 45 28 EGF-like domain hEGF PF12661.7 CBY33706.1 - 1.2e-07 32.1 478.9 0.029 15.0 5.3 46.4 45 1 0 45 45 45 26 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY33706.1 - 2.7e-06 27.5 556.7 0.015 15.6 9.2 46.5 33 9 13 46 46 46 25 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY33706.1 - 0.0047 17.0 11.0 0.0047 17.0 11.0 39.6 40 2 1 41 41 41 16 MSP1 EGF domain 1 Glyco_transf_90 PF05686.12 CBY33708.1 - 3.7e-55 187.5 1.2 5e-55 187.0 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 RST PF12174.8 CBY33708.1 - 0.058 13.3 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain MIP PF00230.20 CBY33709.1 - 1.8e-34 119.5 2.9 2.3e-34 119.1 2.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DPPIV_N PF00930.21 CBY33710.1 - 1e-39 136.3 10.8 7.3e-39 133.5 10.8 2.0 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CBY33710.1 - 8.9e-27 94.0 1.8 1.1e-26 93.7 0.4 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBY33710.1 - 0.00069 20.3 0.1 0.0013 19.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CBY33710.1 - 0.044 13.6 0.1 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NOD2_WH PF17779.1 CBY33710.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 NOD2 winged helix domain Pkinase PF00069.25 CBY33711.1 - 1.2e-50 172.3 0.0 1.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33711.1 - 3.1e-34 118.4 0.0 3.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBY33711.1 - 0.0006 19.5 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CBY33711.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY33711.1 - 0.012 15.6 0.0 4.8 7.0 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY33711.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Mur_ligase_M PF08245.12 CBY33712.1 - 0.32 11.0 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Mur ligase middle domain Mucin PF01456.17 CBY33712.1 - 0.69 9.9 22.4 1.2 9.2 22.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PT PF04886.12 CBY33712.1 - 4.4 6.9 25.0 0.25 10.9 12.6 2.5 2 0 0 2 2 2 0 PT repeat ASFV_J13L PF05568.11 CBY33712.1 - 5.2 6.8 11.1 8.4 6.1 11.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein CUB PF00431.20 CBY33713.1 - 8.1e-10 39.0 0.2 1.6e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 CUB domain Adeno_E3_CR1 PF02440.15 CBY33713.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 ETRAMP PF09716.10 CBY33713.1 - 0.67 10.0 0.0 0.67 10.0 0.0 2.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) HEM4 PF02602.15 CBY33714.1 - 0.13 11.5 0.0 9.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD CH PF00307.31 CBY33715.1 - 1.2e-15 57.7 0.0 2.2e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 CBY33715.1 - 0.0048 17.1 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 CBY33715.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Cullin PF00888.22 CBY33716.1 - 2.7e-56 191.5 6.0 3.1e-56 191.3 6.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.22 CBY33717.1 - 3.2e-34 118.5 5.9 8e-23 80.9 0.8 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 CBY33717.1 - 3.3e-25 87.9 0.9 7.6e-25 86.7 0.9 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain MalF_P2 PF14785.6 CBY33717.1 - 0.091 12.8 1.5 0.17 11.9 1.4 1.4 1 1 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain DUF1834 PF08873.11 CBY33718.1 - 0.12 12.1 0.9 0.9 9.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1834) Pkinase PF00069.25 CBY33719.1 - 3.3e-28 98.8 0.6 5.7e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33719.1 - 1.7e-15 57.0 0.0 3.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase S6PP PF05116.13 CBY33719.1 - 0.13 11.8 5.8 0.19 11.2 5.8 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Endostatin PF06482.11 CBY33719.1 - 0.52 9.7 6.1 0.7 9.3 6.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PNISR PF15996.5 CBY33719.1 - 0.55 10.5 17.3 0.69 10.2 17.2 1.3 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR Androgen_recep PF02166.16 CBY33719.1 - 1.8 7.3 3.4 2.3 7.0 3.4 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4407 PF14362.6 CBY33719.1 - 3.4 6.9 6.8 4.5 6.5 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 CBY33720.1 - 0.00048 19.6 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CBY33721.1 - 3.7e-24 85.5 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33721.1 - 2.1e-06 27.2 0.0 2.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY33721.1 - 0.022 14.1 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like ENTH PF01417.20 CBY33721.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 ENTH domain EGF_CA PF07645.15 CBY33723.1 - 3.1e-59 196.9 178.5 5.5e-11 42.5 4.8 12.9 14 0 0 14 14 14 9 Calcium-binding EGF domain cEGF PF12662.7 CBY33723.1 - 1.3e-37 127.4 91.3 1e-06 28.6 0.6 13.4 12 1 0 12 12 12 10 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY33723.1 - 1.4e-12 47.6 129.0 1e-05 25.6 5.4 12.8 12 1 0 12 12 12 7 EGF domain EGF_MSP1_1 PF12946.7 CBY33723.1 - 3.6e-05 23.7 2.7 3.6e-05 23.7 2.7 11.2 12 0 0 12 12 12 3 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY33723.1 - 0.00018 21.7 11.8 0.00018 21.7 11.8 13.3 12 1 0 13 13 13 7 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY33723.1 - 0.00023 21.6 18.8 0.00085 19.9 3.6 14.5 12 1 0 12 12 12 4 Human growth factor-like EGF EGF PF00008.27 CBY33723.1 - 0.0053 17.0 9.5 0.0053 17.0 9.5 13.5 13 2 0 13 13 13 7 EGF-like domain ASD2 PF08687.11 CBY33723.1 - 0.057 13.0 5.3 0.1 12.2 5.3 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 ATG16 PF08614.11 CBY33724.1 - 0.0093 16.2 10.2 0.018 15.3 10.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mis12 PF05859.12 CBY33724.1 - 0.0096 16.0 4.5 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 Mis12 protein DUF4407 PF14362.6 CBY33724.1 - 0.16 11.3 2.1 0.29 10.5 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4047 PF13256.6 CBY33724.1 - 0.25 11.5 6.4 0.61 10.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) EzrA PF06160.12 CBY33724.1 - 0.33 9.1 11.2 0.53 8.4 8.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 CBY33724.1 - 0.36 8.7 2.5 0.53 8.2 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CREPT PF16566.5 CBY33724.1 - 0.61 10.3 12.2 0.64 10.2 8.6 2.2 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour T3SSipB PF16535.5 CBY33724.1 - 0.65 10.5 5.5 0.41 11.1 1.4 2.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB KIAA1430 PF13879.6 CBY33724.1 - 0.68 10.7 13.0 0.24 12.2 10.0 1.8 2 0 0 2 2 2 0 KIAA1430 homologue betaPIX_CC PF16523.5 CBY33724.1 - 0.94 9.3 12.6 2.9 7.8 9.9 2.7 2 1 0 2 2 2 0 betaPIX coiled coil DUF1664 PF07889.12 CBY33724.1 - 0.98 9.5 6.1 13 5.9 3.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 CBY33724.1 - 1.5 9.4 11.9 0.5 10.8 4.6 2.8 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4570 PF15134.6 CBY33724.1 - 3.9 7.5 10.7 16 5.5 8.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) GED PF02212.18 CBY33724.1 - 4.5 7.5 7.6 2.6 8.2 5.2 1.9 2 0 0 2 2 2 0 Dynamin GTPase effector domain FliD_N PF02465.18 CBY33724.1 - 9.3 7.0 8.5 6.9 7.4 1.9 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Glyco_hydro_9 PF00759.19 CBY33725.1 - 6.8e-56 190.5 0.0 1e-55 189.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ldl_recept_a PF00057.18 CBY33725.1 - 1.2e-09 38.2 8.7 2.1e-09 37.4 8.7 1.4 1 0 0 1 1 1 1 Low-density lipoprotein receptor domain class A MAM PF00629.23 CBY33725.1 - 0.0029 17.5 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu EMP24_GP25L PF01105.24 CBY33726.1 - 4.4e-50 170.2 0.1 4.9e-50 170.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF669 PF05037.13 CBY33726.1 - 0.031 14.4 0.2 22 5.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF669) Peptidase_M18 PF02127.15 CBY33727.1 - 4.9e-165 549.5 0.0 5.8e-165 549.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBY33727.1 - 8.1e-08 31.6 0.3 6.5e-05 22.1 0.2 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase FlgT_C PF16538.5 CBY33727.1 - 0.012 16.1 0.1 1.7 9.3 0.0 2.5 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain PTCB-BRCT PF12738.7 CBY33728.1 - 1.3e-50 169.2 0.7 2.2e-18 66.0 0.1 6.0 6 0 0 6 6 6 5 twin BRCT domain BRCT PF00533.26 CBY33728.1 - 9.4e-45 150.9 0.1 8.1e-10 39.0 0.0 7.0 7 0 0 7 7 7 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY33728.1 - 6.5e-32 109.8 0.3 3e-05 24.3 0.3 7.4 7 0 0 7 7 7 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY33728.1 - 2.6e-09 37.2 1.1 0.029 14.7 0.0 5.9 7 0 0 7 7 7 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CBY33728.1 - 5.2e-08 32.9 0.3 0.018 15.1 0.1 4.8 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Topoisom_I_N PF02919.15 CBY33729.1 - 0.25 10.8 5.0 0.29 10.6 5.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4500 PF14937.6 CBY33730.1 - 0.028 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) BLOC1_2 PF10046.9 CBY33731.1 - 0.0067 16.7 2.1 0.01 16.1 2.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_min_cap2 PF06152.11 CBY33731.1 - 0.0082 15.1 1.5 0.0097 14.8 1.5 1.1 1 0 0 1 1 1 1 Phage minor capsid protein 2 ZapB PF06005.12 CBY33731.1 - 0.063 13.7 6.3 0.14 12.6 6.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB HrpB7 PF09486.10 CBY33731.1 - 0.16 12.4 7.3 0.27 11.6 7.3 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.8 CBY33731.1 - 0.16 11.2 4.3 0.22 10.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ORF6C PF10552.9 CBY33731.1 - 0.3 11.2 4.2 0.36 10.9 2.7 1.9 1 1 1 2 2 2 0 ORF6C domain CENP-H PF05837.12 CBY33731.1 - 0.35 11.3 3.9 0.53 10.7 3.9 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 CBY33731.1 - 0.75 9.9 9.1 0.95 9.5 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CBY33731.1 - 1.7 9.1 7.7 0.84 10.1 0.6 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seadorna_VP6 PF07407.11 CBY33731.1 - 2.9 6.8 6.8 3.5 6.5 6.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DivIC PF04977.15 CBY33731.1 - 5 7.0 12.5 0.91 9.3 2.8 3.0 1 1 2 3 3 3 0 Septum formation initiator Connexin PF00029.19 CBY33732.1 - 5.5e-21 75.4 3.0 3.6e-20 72.7 3.0 2.1 1 1 0 1 1 1 1 Connexin Jiraiya PF15038.6 CBY33732.1 - 0.017 14.6 0.4 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Jiraiya RNA12 PF10443.9 CBY33733.1 - 0.11 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 RNA12 protein ALMT PF11744.8 CBY33733.1 - 0.41 9.4 2.7 0.21 10.4 0.7 1.4 2 0 0 2 2 2 0 Aluminium activated malate transporter DASH_Dam1 PF08653.10 CBY33733.1 - 0.98 9.3 4.8 15 5.5 0.0 4.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 HR1 PF02185.16 CBY33733.1 - 2.6 8.2 7.3 7.3 6.8 0.6 3.3 3 0 0 3 3 3 0 Hr1 repeat Band_7 PF01145.25 CBY33734.1 - 2.8e-23 82.9 7.3 3.9e-23 82.4 7.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY33734.1 - 0.0035 17.1 0.3 0.0063 16.2 0.3 1.4 1 1 0 1 1 1 1 SPFH domain-Band 7 family Kelch_1 PF01344.25 CBY33735.1 - 3.8e-06 26.4 0.9 0.052 13.1 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY33735.1 - 0.0068 16.7 0.0 8.8 6.8 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY33735.1 - 0.013 15.4 3.6 12 6.1 0.0 4.4 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY33735.1 - 0.093 12.8 0.0 1.6 8.8 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain Abhydrolase_1 PF00561.20 CBY33736.1 - 1.1e-05 25.2 0.0 0.0001 22.1 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY33736.1 - 0.012 14.9 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY33736.1 - 0.032 14.9 0.0 0.17 12.4 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family GNT-I PF03071.15 CBY33737.1 - 1.8e-14 53.4 0.1 1.9e-14 53.3 0.1 1.0 1 0 0 1 1 1 1 GNT-I family Bap31 PF05529.12 CBY33738.1 - 1.6e-36 125.1 0.3 1.6e-36 125.1 0.3 1.8 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CBY33738.1 - 3.7e-11 42.8 24.9 3.4e-09 36.6 17.2 3.3 2 1 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 CBY33738.1 - 0.013 14.8 12.5 0.02 14.3 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 CBY33738.1 - 0.04 12.1 7.4 0.049 11.8 7.4 1.0 1 0 0 1 1 1 0 Hsp70 protein Phage_holin_6_1 PF09682.10 CBY33738.1 - 0.043 14.2 4.7 0.075 13.5 3.9 1.8 1 1 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Urate_ox_N PF06181.11 CBY33738.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Urate oxidase N-terminal HAUS6_N PF14661.6 CBY33738.1 - 0.092 12.3 9.6 0.12 12.0 9.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.15 CBY33738.1 - 0.14 11.7 5.5 0.16 11.5 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PIN_8 PF18476.1 CBY33738.1 - 0.24 11.2 8.6 0.38 10.6 8.6 1.3 1 0 0 1 1 1 0 PIN like domain OAD_gamma PF04277.13 CBY33738.1 - 0.75 10.4 11.4 0.78 10.4 1.4 3.3 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MRP-S26 PF14943.6 CBY33738.1 - 0.92 9.4 17.2 1.8 8.5 17.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 ADIP PF11559.8 CBY33738.1 - 1.3 9.1 18.3 2.1 8.4 18.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 CBY33738.1 - 1.3 7.5 9.5 1.8 7.1 9.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 CBY33738.1 - 1.8 8.8 18.1 3.2 8.0 18.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sugarporin_N PF11471.8 CBY33738.1 - 2 8.4 21.0 2 8.4 2.7 3.5 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension Fzo_mitofusin PF04799.13 CBY33738.1 - 2.1 7.9 7.9 3.6 7.1 7.9 1.5 1 0 0 1 1 1 0 fzo-like conserved region Spc7 PF08317.11 CBY33738.1 - 5.8 5.7 22.6 5.6 5.7 21.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein PIEZO PF15917.5 CBY33738.1 - 5.8 6.3 13.1 9.7 5.6 13.1 1.6 1 1 0 1 1 1 0 Piezo BST2 PF16716.5 CBY33738.1 - 7.1 7.3 18.6 3.9 8.1 12.6 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 CBY33738.1 - 8.2 6.2 17.9 15 5.4 17.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Poty_PP PF08440.10 CBY33739.1 - 0.038 13.1 0.2 0.048 12.7 0.2 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein zf-C2H2 PF00096.26 CBY33740.1 - 5.8e-06 26.5 44.7 0.0024 18.2 2.5 8.0 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY33740.1 - 0.00066 20.3 1.8 0.00066 20.3 1.8 8.1 8 0 0 8 8 8 3 C2H2-type zinc finger HTH_19 PF12844.7 CBY33740.1 - 0.0015 18.5 0.2 1.7 8.7 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain zf-H2C2_5 PF13909.6 CBY33740.1 - 0.035 13.9 0.6 0.035 13.9 0.6 4.9 7 0 0 7 7 7 0 C2H2-type zinc-finger domain zf-met PF12874.7 CBY33740.1 - 0.035 14.5 7.3 2.4 8.7 0.4 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY33740.1 - 0.087 13.3 0.2 0.087 13.3 0.2 6.2 7 0 0 7 7 7 0 Zinc-finger double domain Moulting_cycle PF04870.16 CBY33740.1 - 1.5 8.1 14.5 3.5 6.8 4.8 2.2 2 0 0 2 2 2 0 Moulting cycle KH_1 PF00013.29 CBY33742.1 - 8.4e-11 41.5 0.1 1.2e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CBY33742.1 - 0.00027 20.8 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY33742.1 - 0.013 15.3 0.2 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 KH domain Bombinin PF05298.11 CBY33742.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Bombinin bZIP_1 PF00170.21 CBY33743.1 - 3.6e-06 27.0 12.5 9.8e-06 25.6 12.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY33743.1 - 4.4e-05 23.5 16.1 4.4e-05 23.5 16.1 2.1 2 1 0 2 2 2 1 Basic region leucine zipper LCD1 PF09798.9 CBY33743.1 - 0.0042 15.7 0.2 0.0058 15.2 0.2 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein HOOK PF05622.12 CBY33743.1 - 0.0071 14.6 0.3 0.011 13.9 0.3 1.2 1 0 0 1 1 1 1 HOOK protein YabA PF06156.13 CBY33743.1 - 1.3 9.7 8.2 0.75 10.5 1.9 2.4 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_Maf PF03131.17 CBY33743.1 - 3.9 8.1 14.0 0.12 13.0 7.3 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Pox_G5 PF04599.12 CBY33743.1 - 6.1 5.7 4.7 8.5 5.3 4.7 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein Presenilin PF01080.17 CBY33744.1 - 0.89 8.2 5.6 1.3 7.7 5.6 1.2 1 0 0 1 1 1 0 Presenilin Cadherin_C_2 PF16492.5 CBY33748.1 - 0.015 16.1 0.0 0.047 14.4 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Orf78 PF06024.12 CBY33748.1 - 0.079 13.3 1.0 0.28 11.5 1.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) Corona_S2 PF01601.16 CBY33748.1 - 8.9 4.7 13.6 13 4.1 13.6 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ig_2 PF13895.6 CBY33751.1 - 2.4e-07 31.0 0.2 0.032 14.6 0.0 2.9 2 1 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY33751.1 - 2.9e-07 30.5 0.3 1.4e-05 25.0 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY33751.1 - 0.001 19.6 0.3 0.7 10.5 0.1 3.3 2 1 1 3 3 3 1 Immunoglobulin domain Big_7 PF17957.1 CBY33751.1 - 0.01 16.6 0.3 0.68 10.7 0.0 3.3 2 2 0 3 3 3 0 Bacterial Ig domain SCF PF02404.15 CBY33751.1 - 0.015 14.6 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Stem cell factor Cadherin_C_2 PF16492.5 CBY33751.1 - 0.02 15.6 0.0 0.053 14.3 0.0 1.7 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Glt_symporter PF03616.14 CBY33751.1 - 0.048 12.4 0.0 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter ig PF00047.25 CBY33751.1 - 0.41 10.8 3.2 2.4 8.4 0.1 3.3 3 1 0 3 3 3 0 Immunoglobulin domain PHD_2 PF13831.6 CBY33753.1 - 0.052 13.1 5.1 2.4 7.8 5.2 2.5 1 1 0 1 1 1 0 PHD-finger RRM_1 PF00076.22 CBY33754.1 - 5.5e-21 74.2 0.0 8e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY33754.1 - 0.0013 18.5 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY33754.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY33754.1 - 0.062 13.4 0.0 0.062 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RR_TM4-6 PF06459.12 CBY33754.1 - 1.1 9.0 3.5 1.3 8.7 3.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ceramidase_alk PF04734.13 CBY33757.1 - 2e-140 468.8 0.0 2.5e-140 468.5 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CBY33757.1 - 1e-07 32.0 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, C-terminal LRR_8 PF13855.6 CBY33758.1 - 3.7e-06 26.6 1.1 9.2e-05 22.1 0.2 2.0 2 0 0 2 2 2 2 Leucine rich repeat CCDC53 PF10152.9 CBY33759.1 - 3.1 8.2 9.6 0.22 11.9 3.7 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HTH_21 PF13276.6 CBY33760.1 - 0.028 14.6 0.1 0.028 14.6 0.1 1.0 1 0 0 1 1 1 0 HTH-like domain Ig_2 PF13895.6 CBY33763.1 - 0.00058 20.1 0.1 0.063 13.6 0.1 2.7 2 0 0 2 2 2 1 Immunoglobulin domain Syndecan PF01034.20 CBY33763.1 - 0.00065 19.6 0.1 0.002 18.0 0.1 1.8 2 0 0 2 2 2 1 Syndecan domain TMEM154 PF15102.6 CBY33763.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CBY33763.1 - 0.1 13.5 0.0 0.32 11.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HTH_7 PF02796.15 CBY33765.1 - 0.076 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase FSA_C PF10479.9 CBY33766.1 - 2.7e-49 168.0 14.2 8.7e-18 63.8 0.1 4.6 3 1 2 5 5 5 4 Fragile site-associated protein C-terminus Pro_isomerase PF00160.21 CBY33767.1 - 9.1e-48 162.5 0.2 1e-47 162.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Proteasome PF00227.26 CBY33769.1 - 4.4e-27 94.8 0.0 5.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RelB_N PF18506.1 CBY33769.1 - 0.067 13.0 1.7 0.15 11.9 1.7 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain KfrA_N PF11740.8 CBY33772.1 - 0.015 16.0 0.0 0.023 15.4 0.0 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RPN1_C PF18051.1 CBY33772.1 - 0.1 12.6 0.3 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal zf-C2H2_4 PF13894.6 CBY33773.1 - 3.2e-09 36.8 27.9 0.0033 18.1 0.3 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY33773.1 - 4.9e-07 29.8 28.5 0.004 17.5 0.4 5.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CBY33773.1 - 0.00013 21.7 0.5 0.012 15.4 0.0 3.7 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY33773.1 - 0.0066 16.4 1.3 0.0066 16.4 1.3 4.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY33773.1 - 0.023 15.4 0.9 0.023 15.4 0.9 3.7 2 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CBY33773.1 - 0.24 11.8 8.6 3.9 8.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TF_Zn_Ribbon PF08271.12 CBY33773.1 - 0.5 9.9 10.4 2.7 7.6 0.0 4.6 4 0 0 4 4 4 0 TFIIB zinc-binding zf-C2H2_2 PF12756.7 CBY33773.1 - 5.3 7.4 32.0 4.7 7.6 8.7 4.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) Sulfotransfer_4 PF17784.1 CBY33774.1 - 3.8e-51 174.0 0.1 4.5e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain FKBP_C PF00254.28 CBY33775.1 - 5.5e-36 122.8 0.0 6.9e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ANF_receptor PF01094.28 CBY33775.1 - 0.25 10.4 0.0 0.3 10.2 0.0 1.0 1 0 0 1 1 1 0 Receptor family ligand binding region DEAD PF00270.29 CBY33776.1 - 1.9e-15 57.1 0.0 3.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Vps39_2 PF10367.9 CBY33776.1 - 0.025 15.0 0.1 0.07 13.6 0.1 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Paralemmin PF03285.15 CBY33777.1 - 0.033 13.8 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Paralemmin Trypsin PF00089.26 CBY33778.1 - 8.8e-31 107.4 0.0 1.1e-30 107.1 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY33778.1 - 0.024 15.5 0.0 0.049 14.5 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain Trypsin PF00089.26 CBY33781.1 - 1.1e-49 169.2 0.5 1.1e-49 169.2 0.5 2.4 3 0 0 3 3 3 1 Trypsin TSP_1 PF00090.19 CBY33781.1 - 1.8e-12 47.3 45.0 1.5e-07 31.5 8.6 4.7 5 1 0 5 5 5 3 Thrombospondin type 1 domain Trypsin_2 PF13365.6 CBY33781.1 - 1.8e-05 25.7 0.0 4.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain 7tm_1 PF00001.21 CBY33782.1 - 8.5e-32 110.5 7.4 1.5e-31 109.7 7.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY33782.1 - 5.3e-07 29.2 7.7 7.5e-07 28.7 7.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srv PF10323.9 CBY33782.1 - 0.0055 16.1 11.2 0.0056 16.1 0.3 2.8 3 0 0 3 3 3 2 Serpentine type 7TM GPCR chemoreceptor Srv DcuC PF03606.15 CBY33782.1 - 0.014 13.9 0.1 0.028 12.9 0.1 1.4 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF3899 PF13038.6 CBY33782.1 - 0.19 12.3 0.2 0.19 12.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) OAD_gamma PF04277.13 CBY33782.1 - 0.24 12.0 0.4 0.82 10.3 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Stevor PF17410.2 CBY33782.1 - 0.24 10.9 4.9 0.045 13.3 1.0 1.7 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame 7tm_1 PF00001.21 CBY33783.1 - 7.7e-14 51.6 2.2 1.5e-13 50.7 2.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) tRNA_synthFbeta PF17759.1 CBY33784.1 - 0.29 10.5 3.2 0.43 10.0 1.8 2.0 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain adh_short PF00106.25 CBY33785.1 - 8.7e-17 61.2 0.1 1e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY33785.1 - 2.1e-11 43.9 0.0 2.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY33785.1 - 1.4e-08 34.8 0.0 1.8e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 KR domain CRR7 PF12095.8 CBY33785.1 - 0.0094 16.4 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein CHLORORESPIRATORY REDUCTION 7 Eno-Rase_NADH_b PF12242.8 CBY33785.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 CBY33785.1 - 0.085 12.2 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY33785.1 - 0.089 12.2 0.1 0.78 9.2 0.0 1.9 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family EGF_2 PF07974.13 CBY33789.1 - 0.00044 20.6 14.0 0.00044 20.6 14.0 3.0 3 0 0 3 3 3 1 EGF-like domain hEGF PF12661.7 CBY33789.1 - 0.0023 18.5 5.6 0.0023 18.5 5.6 4.2 6 0 0 6 6 6 1 Human growth factor-like EGF Laminin_EGF PF00053.24 CBY33789.1 - 0.019 15.1 24.1 2.5 8.3 15.9 3.6 1 1 2 3 3 3 0 Laminin EGF domain EGF PF00008.27 CBY33789.1 - 0.026 14.8 11.0 0.026 14.8 11.0 3.2 3 0 0 3 3 3 0 EGF-like domain IF4E PF01652.18 CBY33789.1 - 0.2 11.4 0.2 0.4 10.5 0.1 1.5 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E Trypsin PF00089.26 CBY33790.1 - 3.2e-46 157.9 0.2 3.2e-46 157.9 0.2 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY33790.1 - 1.2e-06 29.5 0.0 2.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY33790.1 - 0.0062 16.1 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Chymotrypsin family Peptidase-S1 C2-set_2 PF08205.12 CBY33791.1 - 2e-17 63.0 0.3 2.2e-12 46.9 0.0 2.7 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY33791.1 - 3.2e-11 43.7 1.1 0.0012 19.4 0.0 3.6 3 1 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY33791.1 - 6.8e-11 42.4 0.1 0.014 15.8 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CBY33791.1 - 2.9e-10 40.2 2.6 5.6e-05 23.2 0.5 3.4 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY33791.1 - 1.4e-08 34.6 0.5 0.0028 17.7 0.0 3.4 3 0 0 3 3 3 3 Immunoglobulin I-set domain C1-set PF07654.15 CBY33791.1 - 0.019 15.3 0.0 0.073 13.5 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin C1-set domain ECSCR PF15820.5 CBY33791.1 - 0.24 11.3 4.9 0.39 10.6 2.8 2.2 1 1 1 2 2 2 0 Endothelial cell-specific chemotaxis regulator TraE PF05309.11 CBY33791.1 - 0.32 10.3 2.1 0.61 9.4 2.1 1.4 1 0 0 1 1 1 0 TraE protein Sulfatase PF00884.23 CBY33792.1 - 5.3e-51 173.9 0.2 6e-51 173.7 0.2 1.0 1 0 0 1 1 1 1 Sulfatase CUB PF00431.20 CBY33793.1 - 1.2e-10 41.7 0.0 2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 CUB domain Connexin PF00029.19 CBY33795.1 - 2e-56 191.4 8.2 2.5e-56 191.1 8.2 1.1 1 0 0 1 1 1 1 Connexin Chordopox_G3 PF06129.12 CBY33795.1 - 0.17 12.6 1.6 6.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus G3 protein Orf78 PF06024.12 CBY33795.1 - 0.19 12.0 2.7 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Orf78 (ac78) OAD_gamma PF04277.13 CBY33795.1 - 0.62 10.7 3.1 1.9 9.1 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ac76 PF05814.11 CBY33795.1 - 4.1 7.5 6.1 1.5 8.9 0.1 2.6 3 0 0 3 3 3 0 Orf76 (Ac76) TctB PF07331.11 CBY33796.1 - 0.00021 21.6 2.4 0.00021 21.6 2.4 1.7 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Orai-1 PF07856.12 CBY33796.1 - 0.00064 19.5 0.3 0.0011 18.7 0.3 1.5 1 1 0 1 1 1 1 Mediator of CRAC channel activity DUF2569 PF10754.9 CBY33796.1 - 0.1 13.0 3.6 0.09 13.2 1.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Bax1-I PF01027.20 CBY33796.1 - 0.25 11.1 9.0 0.84 9.4 8.1 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DHHC PF01529.20 CBY33796.1 - 7.2 6.7 11.0 3.7 7.7 2.1 2.4 1 1 2 3 3 3 0 DHHC palmitoyltransferase PQQ PF01011.21 CBY33797.1 - 0.00088 19.1 0.0 0.0037 17.1 0.0 2.2 1 0 0 1 1 1 1 PQQ enzyme repeat KTSC PF13619.6 CBY33797.1 - 0.0083 15.9 0.1 0.097 12.5 0.1 2.6 2 0 0 2 2 2 1 KTSC domain ASXH PF13919.6 CBY33798.1 - 0.041 13.9 0.3 0.1 12.6 0.0 1.7 1 1 1 2 2 2 0 Asx homology domain ABC2_membrane PF01061.24 CBY33799.1 - 6.9e-12 45.2 13.8 8.8e-12 44.9 13.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBY33799.1 - 0.53 9.3 11.9 0.64 9.1 11.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Glyco_hydro_35 PF01301.19 CBY33800.1 - 6.7e-97 324.9 0.5 1.8e-96 323.5 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY33800.1 - 5.9e-11 42.3 0.0 2e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 Beta-galactosidase FBA PF04300.13 CBY33800.1 - 0.05 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box associated region BetaGal_dom4_5 PF13364.6 CBY33800.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain EF-hand_7 PF13499.6 CBY33801.1 - 2e-24 85.8 3.1 2.6e-15 56.6 0.4 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBY33801.1 - 3.3e-24 82.6 6.8 5.4e-07 28.7 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBY33801.1 - 2.6e-21 73.7 3.2 6.2e-06 25.7 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY33801.1 - 1.5e-18 65.3 7.4 4.1e-06 26.0 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY33801.1 - 6.5e-14 51.5 6.6 3e-06 27.0 0.3 4.2 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY33801.1 - 9.2e-05 22.4 1.7 3.3 7.7 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY33801.1 - 0.00016 22.0 0.5 2.5 8.5 0.1 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY33801.1 - 0.0018 18.5 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 CBY33801.1 - 0.0052 16.7 0.3 17 5.3 0.0 3.3 1 1 1 3 3 3 0 Caleosin related protein Homeodomain PF00046.29 CBY33801.1 - 0.027 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain Homez PF11569.8 CBY33801.1 - 0.031 13.7 0.1 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Dockerin_1 PF00404.18 CBY33801.1 - 0.051 13.8 0.0 5.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Dockerin type I domain S10_plectin PF03501.15 CBY33801.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain BetaGal_dom4_5 PF13364.6 CBY33802.1 - 0.025 15.1 0.1 0.055 14.1 0.1 1.6 1 1 0 1 1 1 0 Beta-galactosidase jelly roll domain FemAB_like PF04339.12 CBY33803.1 - 0.12 11.4 0.7 0.11 11.6 0.7 1.1 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Glyco_transf_7N PF13733.6 CBY33804.1 - 2.5e-36 124.3 0.7 3.9e-36 123.7 0.7 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY33804.1 - 1e-25 89.2 1.7 1.7e-25 88.4 0.9 1.7 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase MFS_2 PF13347.6 CBY33805.1 - 8.8e-10 37.7 5.4 1e-09 37.5 5.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CBY33805.1 - 1.8e-08 33.7 6.6 1.8e-08 33.7 6.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY33805.1 - 0.0016 17.4 1.6 0.0016 17.4 1.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 CBY33805.1 - 0.085 11.5 5.3 0.12 11.0 5.3 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like MFS_2 PF13347.6 CBY33806.1 - 1.8e-11 43.3 3.1 2.3e-11 42.9 3.1 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CBY33806.1 - 2.5e-10 39.8 4.8 2.5e-10 39.8 4.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY33806.1 - 0.00049 19.1 1.1 0.00049 19.1 1.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 CBY33806.1 - 0.044 12.4 4.3 0.058 12.0 4.3 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Thioredoxin PF00085.20 CBY33807.1 - 4.3e-15 55.6 0.7 6.9e-15 54.9 0.7 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY33807.1 - 0.0045 17.4 0.3 0.026 15.0 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Inovirus_Gp2 PF11726.8 CBY33807.1 - 0.0053 16.7 0.1 0.0074 16.3 0.1 1.3 1 0 0 1 1 1 1 Inovirus Gp2 DUF1223 PF06764.11 CBY33807.1 - 0.018 15.1 1.1 0.78 9.7 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) Thioredoxin_5 PF13743.6 CBY33807.1 - 0.032 13.9 1.4 4.6 6.9 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin FMN_dh PF01070.18 CBY33807.1 - 0.069 12.2 0.1 0.073 12.1 0.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Thioredoxin_8 PF13905.6 CBY33807.1 - 0.2 12.0 3.3 0.28 11.5 0.2 2.3 2 1 1 3 3 3 0 Thioredoxin-like Glyco_hydro_79n PF03662.14 CBY33808.1 - 1.1e-22 80.4 0.3 1.6e-22 79.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_79n PF03662.14 CBY33809.1 - 1.7e-27 96.2 0.6 1.2e-17 63.8 0.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 79, N-terminal domain DUF1235 PF06822.12 CBY33810.1 - 0.015 14.6 0.2 0.018 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Get5_C PF18514.1 CBY33810.1 - 0.037 13.7 0.4 2.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Get5 C-terminal domain RE_ApaLI PF09499.10 CBY33810.1 - 0.076 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Isochorismatase PF00857.20 CBY33811.1 - 1e-08 35.5 0.0 1.4e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.13 CBY33812.1 - 3.5e-39 134.9 0.0 6.2e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY33812.1 - 6.3e-07 28.6 0.1 1.8e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CBY33812.1 - 0.031 14.9 0.0 0.041 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 CBY33812.1 - 0.078 11.5 0.2 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SBP_bac_5 PF00496.22 CBY33812.1 - 0.088 11.8 0.2 0.17 10.8 0.1 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Qn_am_d_aIII PF09099.10 CBY33812.1 - 0.095 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III PALP PF00291.25 CBY33813.1 - 1.2e-47 162.8 0.0 1.4e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SnoaL_2 PF12680.7 CBY33813.1 - 0.19 12.4 0.0 0.35 11.6 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain PALP PF00291.25 CBY33814.1 - 9.6e-12 44.9 0.0 1.1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.7 CBY33815.1 - 2.6e-32 111.2 1.5 5.4e-09 36.5 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 CBY33815.1 - 9.7e-24 82.7 0.7 0.0011 19.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CBY33815.1 - 2.4e-23 82.2 0.1 0.002 18.7 0.0 6.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY33815.1 - 6.8e-22 77.2 0.0 4.6e-05 23.6 0.0 5.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33815.1 - 5e-16 57.2 0.0 0.053 14.1 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat FBA_1 PF07734.13 CBY33815.1 - 0.061 13.2 0.7 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 F-box associated FKBP_C PF00254.28 CBY33816.1 - 4.5e-33 113.4 0.0 5.1e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.22 CBY33817.1 - 2.1e-58 196.5 0.9 2.4e-58 196.3 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33817.1 - 2.9e-37 127.5 0.2 4.4e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY33817.1 - 2.4e-15 56.4 0.3 2.6e-15 56.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY33817.1 - 8.9e-07 29.0 0.6 0.023 14.6 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY33817.1 - 9.5e-06 25.7 0.1 1.7e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY33817.1 - 9.8e-06 25.1 0.4 1.2e-05 24.8 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY33817.1 - 6.3e-05 22.6 0.3 0.0011 18.5 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY33817.1 - 0.00012 21.5 0.1 0.00017 21.1 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CBY33817.1 - 0.00069 19.9 0.0 0.05 13.9 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBY33817.1 - 0.0024 17.4 0.1 0.005 16.4 0.0 1.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CBY33817.1 - 0.0035 17.3 0.1 0.0064 16.4 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CBY33817.1 - 0.0041 17.5 0.0 0.0086 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CBY33817.1 - 0.018 14.8 0.4 0.044 13.5 0.4 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CBY33817.1 - 0.029 14.1 0.2 0.05 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CBY33817.1 - 0.046 13.7 0.2 0.065 13.2 0.2 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit MMR_HSR1_Xtn PF16897.5 CBY33817.1 - 0.082 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NACHT PF05729.12 CBY33817.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CBY33817.1 - 0.12 12.8 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter SurA_N_2 PF13623.6 CBY33819.1 - 0.7 9.7 8.3 0.11 12.3 1.6 2.8 2 1 1 3 3 3 0 SurA N-terminal domain E2F_CC-MB PF16421.5 CBY33819.1 - 1 9.8 8.3 0.61 10.5 0.3 2.9 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Zona_pellucida PF00100.23 CBY33820.1 - 2.3e-11 44.0 0.0 3.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain I-set PF07679.16 CBY33821.1 - 1.4e-172 560.4 63.3 5.3e-12 45.6 0.0 23.2 21 2 2 23 23 23 23 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY33821.1 - 5e-98 321.8 11.8 7.6e-07 29.6 0.1 22.3 22 1 1 23 23 23 17 Immunoglobulin domain ig PF00047.25 CBY33821.1 - 2.3e-53 178.3 24.0 0.00014 22.0 0.0 17.4 19 2 0 19 19 18 11 Immunoglobulin domain Ig_2 PF13895.6 CBY33821.1 - 6.1e-51 170.7 5.4 0.00033 20.9 0.0 16.6 17 1 1 18 18 18 10 Immunoglobulin domain V-set PF07686.17 CBY33821.1 - 7.8e-24 84.0 8.6 0.88 9.8 0.0 15.7 15 2 1 16 16 16 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY33821.1 - 2e-16 59.8 10.2 0.0049 16.9 0.0 10.8 11 0 0 11 11 11 5 Izumo-like Immunoglobulin domain BiPBP_C PF06832.12 CBY33821.1 - 9e-11 41.7 0.0 0.32 11.0 0.0 9.5 10 0 0 10 10 10 1 Penicillin-Binding Protein C-terminus Family C2-set_2 PF08205.12 CBY33821.1 - 1.9e-09 37.4 2.5 0.22 11.6 0.0 9.7 11 0 0 11 11 11 1 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CBY33821.1 - 1e-08 35.3 6.0 1.7 9.0 0.0 10.6 11 0 0 11 11 11 1 T-cell surface glycoprotein CD3 delta chain Fn3-like PF14310.6 CBY33821.1 - 0.0046 17.0 0.1 0.74 10.0 0.1 4.3 3 0 0 3 3 3 1 Fibronectin type III-like domain Herpes_gE PF02480.16 CBY33821.1 - 0.0056 15.5 1.0 0.38 9.5 0.0 3.7 4 1 0 4 4 4 1 Alphaherpesvirus glycoprotein E C2-set PF05790.15 CBY33821.1 - 0.1 12.8 2.2 42 4.4 0.1 5.5 6 0 0 6 6 6 0 Immunoglobulin C2-set domain I-set PF07679.16 CBY33822.1 - 5.7e-62 205.8 0.8 3.7e-19 68.6 0.0 4.4 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY33822.1 - 7.4e-41 138.6 0.0 8.2e-14 52.0 0.0 4.7 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 CBY33822.1 - 1.2e-27 95.8 0.0 7.4e-09 35.7 0.0 4.3 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY33822.1 - 1.9e-22 79.4 0.0 2.1e-08 34.3 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain V-set PF07686.17 CBY33822.1 - 2.2e-12 47.1 0.0 4.6e-05 23.6 0.0 5.4 4 1 0 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY33822.1 - 5.6e-05 23.1 0.1 0.41 10.7 0.0 2.8 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY33822.1 - 0.0042 17.1 0.1 20 5.4 0.1 4.4 4 1 0 4 4 4 0 CD80-like C2-set immunoglobulin domain Ig_C17orf99 PF17736.1 CBY33822.1 - 0.016 15.3 0.0 0.051 13.6 0.0 2.0 2 0 0 2 2 2 0 C17orf99 Ig domain Ig_4 PF16680.5 CBY33822.1 - 0.05 13.9 4.2 2 8.8 0.1 3.8 4 1 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain Herpes_gE PF02480.16 CBY33822.1 - 0.1 11.3 0.1 4.5 5.9 0.0 2.7 2 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E Phospholip_A2_1 PF00068.19 CBY33823.1 - 1.4e-15 57.7 6.1 1.4e-15 57.7 6.1 2.0 2 0 0 2 2 2 1 Phospholipase A2 PLA2G12 PF06951.11 CBY33823.1 - 0.022 14.7 1.1 0.022 14.7 1.1 2.7 2 1 0 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) I-set PF07679.16 CBY33824.1 - 2.4e-203 658.9 22.0 4.4e-16 58.7 0.0 17.3 17 0 0 17 17 17 17 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY33824.1 - 1.6e-120 393.9 1.2 1.3e-11 44.9 0.0 17.5 17 0 0 17 17 17 16 Immunoglobulin domain Ig_2 PF13895.6 CBY33824.1 - 1.3e-50 169.7 9.5 0.00068 19.9 0.0 15.4 16 0 0 16 16 16 8 Immunoglobulin domain ig PF00047.25 CBY33824.1 - 2.5e-42 143.0 9.6 1.2e-06 28.6 0.0 14.4 15 0 0 15 15 15 8 Immunoglobulin domain V-set PF07686.17 CBY33824.1 - 2.2e-21 76.1 6.7 0.039 14.1 0.0 15.8 15 2 0 15 15 15 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY33824.1 - 3.7e-17 62.2 0.8 0.038 14.1 0.0 8.6 8 0 0 8 8 8 4 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY33824.1 - 7.7e-09 35.5 0.1 6.5 6.9 0.0 8.0 8 0 0 8 8 8 2 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 CBY33824.1 - 7.1e-06 26.0 1.6 0.013 15.5 0.0 6.2 7 0 0 7 7 7 1 Izumo-like Immunoglobulin domain Herpes_gE PF02480.16 CBY33824.1 - 8.9e-06 24.7 6.9 1.5 7.4 0.0 7.5 5 1 3 9 9 9 2 Alphaherpesvirus glycoprotein E C1-set PF07654.15 CBY33824.1 - 0.0063 16.9 12.7 0.16 12.3 0.0 6.9 8 0 0 8 8 5 1 Immunoglobulin C1-set domain Ig_4 PF16680.5 CBY33824.1 - 0.0074 16.5 0.3 49 4.3 0.0 6.5 7 0 0 7 7 7 0 T-cell surface glycoprotein CD3 delta chain YqbF PF14553.6 CBY33824.1 - 0.017 15.0 0.5 4.5 7.2 0.2 3.4 3 0 0 3 3 3 0 YqbF, hypothetical protein domain DUF4982 PF16355.5 CBY33824.1 - 0.033 14.1 0.0 0.17 11.9 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) Ig_6 PF18452.1 CBY33824.1 - 0.05 13.2 0.0 1.1 8.9 0.0 3.5 3 0 0 3 3 3 0 Immunoglobulin domain DUF11 PF01345.18 CBY33824.1 - 0.16 12.3 4.2 3.6 7.9 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function DUF11 EGF_CA PF07645.15 CBY33825.1 - 1.1e-221 716.9 588.7 1.2e-09 38.2 8.8 36.5 34 2 2 36 36 36 34 Calcium-binding EGF domain cEGF PF12662.7 CBY33825.1 - 6.5e-137 444.8 347.6 1.8e-09 37.3 1.2 37.7 37 0 0 37 37 37 33 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY33825.1 - 7.9e-68 224.4 552.5 9.4e-08 32.2 8.8 37.1 35 2 2 37 37 37 29 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY33825.1 - 4.2e-65 215.6 528.8 0.00062 20.0 7.4 38.6 36 1 1 37 37 37 32 EGF-like domain EGF_3 PF12947.7 CBY33825.1 - 3e-43 145.7 516.8 5.4e-09 36.1 12.1 37.0 36 1 0 36 36 36 24 EGF domain hEGF PF12661.7 CBY33825.1 - 1.6e-28 98.3 536.0 0.0008 19.9 6.2 42.6 42 3 0 42 42 42 27 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY33825.1 - 7.1e-16 58.2 444.0 0.013 15.8 11.2 35.7 33 3 2 35 35 35 24 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CBY33825.1 - 2.4e-05 24.3 16.5 0.00011 22.1 2.7 34.2 33 5 4 37 37 37 11 MSP1 EGF domain 1 TIL PF01826.17 CBY33825.1 - 0.0048 17.1 2.8 0.0048 17.1 2.8 34.8 17 10 13 30 30 30 9 Trypsin Inhibitor like cysteine rich domain NHL PF01436.21 CBY33825.1 - 1.8 8.7 9.1 33 4.8 0.3 5.4 4 0 0 4 4 4 0 NHL repeat PDZ_6 PF17820.1 CBY33827.1 - 9.4e-12 44.6 0.6 4.8e-11 42.3 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 CBY33827.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Glutaredoxin PF00462.24 CBY33827.1 - 2.2e-06 27.8 0.0 8.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin PDZ_2 PF13180.6 CBY33827.1 - 0.00016 22.0 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SH3BGR PF04908.15 CBY33827.1 - 0.0081 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Zn_ribbon_recom PF13408.6 CBY33827.1 - 0.019 15.5 1.2 0.047 14.2 1.2 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain FYVE PF01363.21 CBY33827.1 - 2.7 8.2 9.7 6.8 6.9 9.7 1.6 1 0 0 1 1 1 0 FYVE zinc finger DnaJ_CXXCXGXG PF00684.19 CBY33827.1 - 4.4 7.7 15.9 0.18 12.2 3.8 2.5 1 1 1 2 2 2 0 DnaJ central domain Pkinase_Tyr PF07714.17 CBY33828.1 - 3.3e-77 259.3 0.0 9.4e-77 257.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33828.1 - 6.8e-34 117.4 0.0 1.3e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GF_recep_IV PF14843.6 CBY33828.1 - 5.2e-06 26.3 31.8 5.2e-06 26.3 31.8 2.1 1 1 0 1 1 1 1 Growth factor receptor domain IV TMEMspv1-c74-12 PF11044.8 CBY33828.1 - 0.027 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Haspin_kinase PF12330.8 CBY33828.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain P4Ha_N PF08336.11 CBY33829.1 - 2.4e-22 79.4 1.1 2.4e-22 79.4 1.1 1.7 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY33829.1 - 1.4e-13 51.5 0.1 1.2e-12 48.6 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.6 CBY33829.1 - 0.21 12.3 2.0 0.61 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY33830.1 - 9.1e-17 61.1 9.6 3.1e-06 27.4 0.7 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY33830.1 - 5e-11 41.8 13.6 0.15 12.2 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY33830.1 - 1.1e-09 38.3 7.3 0.00019 21.6 0.3 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBY33830.1 - 7.9e-08 31.8 15.1 0.0051 16.6 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY33830.1 - 1.8e-06 27.5 1.5 0.068 12.9 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 CBY33830.1 - 6.2e-06 26.6 9.4 0.094 13.2 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY33830.1 - 8.7e-06 26.3 5.6 0.0057 17.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 CBY33830.1 - 4.6e-05 23.2 8.2 0.00028 20.6 3.6 2.9 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 CBY33830.1 - 0.00013 21.7 9.6 0.28 11.3 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY33830.1 - 0.00024 21.6 9.1 11 7.2 0.1 6.3 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY33830.1 - 0.00061 19.8 13.2 1.9 8.9 0.2 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY33830.1 - 0.0046 16.4 2.9 0.022 14.1 3.0 1.8 2 0 0 2 2 2 1 MalT-like TPR region ANTH PF07651.16 CBY33830.1 - 0.0069 15.4 0.3 0.011 14.8 0.3 1.4 1 0 0 1 1 1 1 ANTH domain TPR_17 PF13431.6 CBY33830.1 - 0.024 15.0 4.5 3.2 8.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBY33830.1 - 0.033 14.8 2.5 19 6.3 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBY33830.1 - 0.064 13.0 6.9 1.4 8.6 4.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CBY33830.1 - 0.16 11.9 13.7 0.22 11.4 0.5 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY33830.1 - 0.92 10.3 9.2 43 5.0 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat CI-B14_5a PF07347.12 CBY33832.1 - 1.2e-11 44.4 0.4 1.6e-11 44.0 0.4 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ank_2 PF12796.7 CBY33833.1 - 1.6e-07 31.8 0.5 4.4e-07 30.4 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY33833.1 - 2.6e-07 30.4 0.1 0.00083 19.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY33833.1 - 3.5e-06 27.2 0.1 0.00011 22.4 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 CBY33833.1 - 1e-05 26.2 0.0 0.0001 22.9 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ank_4 PF13637.6 CBY33833.1 - 0.00027 21.4 0.0 0.0019 18.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY33833.1 - 0.003 17.9 0.2 0.13 12.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat MqsR_toxin PF15723.5 CBY33833.1 - 0.0043 17.4 0.4 15 6.0 0.0 3.6 3 0 0 3 3 3 1 Motility quorum-sensing regulator, toxin of MqsA Methyltransf_11 PF08241.12 CBY33833.1 - 0.0078 16.8 0.0 0.03 15.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Baculo_PEP_C PF04513.12 CBY33834.1 - 0.00087 19.3 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 CBY33834.1 - 0.0046 17.2 7.8 0.0061 16.8 7.8 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 AI-2E_transport PF01594.16 CBY33834.1 - 0.014 14.6 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter Neur_chan_memb PF02932.16 CBY33834.1 - 0.07 13.2 0.8 0.1 12.6 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Prominin PF05478.11 CBY33834.1 - 0.11 10.5 4.2 0.13 10.2 4.2 1.1 1 0 0 1 1 1 0 Prominin DUF4337 PF14235.6 CBY33834.1 - 0.16 12.1 1.1 0.21 11.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SID-1_RNA_chan PF13965.6 CBY33834.1 - 0.2 10.0 1.2 0.23 9.8 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRF PF01765.19 CBY33834.1 - 0.26 11.2 8.0 5.7 6.9 7.9 2.3 2 1 0 2 2 2 0 Ribosome recycling factor DUF4446 PF14584.6 CBY33834.1 - 0.74 9.8 5.0 3.4 7.6 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.10 CBY33834.1 - 1.5 8.9 8.4 0.37 10.9 2.9 1.9 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Atg14 PF10186.9 CBY33834.1 - 2.2 7.3 9.4 3 6.9 9.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kelch_5 PF13854.6 CBY33835.1 - 3.6e-16 58.8 0.0 6e-06 26.1 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 CBY33835.1 - 2e-15 56.5 0.7 0.028 14.4 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY33835.1 - 7.4e-13 48.4 0.9 0.019 15.2 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY33835.1 - 1.1e-07 31.9 0.0 0.18 12.1 0.0 5.5 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY33835.1 - 0.00046 19.7 0.0 0.24 11.0 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Antimicrobial_7 PF08102.11 CBY33836.1 - 0.14 12.4 0.7 9.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF2228 PF10228.9 CBY33837.1 - 3.3e-56 190.8 0.0 3.3e-56 190.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2228) SEP PF08059.13 CBY33837.1 - 0.095 13.3 0.2 0.42 11.2 0.1 2.2 2 0 0 2 2 2 0 SEP domain Ion_trans PF00520.31 CBY33838.1 - 1.1e-21 77.3 12.1 1.4e-21 76.9 12.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY33838.1 - 2.5e-10 40.2 0.9 2.5e-10 40.2 0.9 2.2 2 1 0 2 2 2 1 Ion channel Beta_helix PF13229.6 CBY33840.1 - 1.8e-07 31.2 1.7 1.4e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 Right handed beta helix region DUF1348 PF07080.11 CBY33840.1 - 0.03 14.3 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) NosD PF05048.13 CBY33840.1 - 0.03 13.6 0.2 0.16 11.2 0.0 2.1 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) WD40 PF00400.32 CBY33841.1 - 2.9e-11 43.7 5.9 0.00026 21.7 0.6 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY33841.1 - 4.7e-05 23.6 0.6 0.95 9.8 0.1 4.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CBY33841.1 - 0.053 12.4 0.2 0.22 10.4 0.0 2.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pur_ac_phosph_N PF16656.5 CBY33841.1 - 5.9 7.5 6.5 1.3 9.7 0.3 3.0 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain DUF3097 PF11296.8 CBY33842.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) Connexin PF00029.19 CBY33843.1 - 1.2e-14 54.7 0.6 1.4e-14 54.4 0.6 1.1 1 0 0 1 1 1 1 Connexin ALG11_N PF15924.5 CBY33843.1 - 0.0066 16.5 0.4 0.0091 16.1 0.4 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus RhoGAP PF00620.27 CBY33846.1 - 6.2e-27 94.3 0.2 2e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain IRK_C PF17655.1 CBY33847.1 - 8.8e-65 217.5 0.0 1.1e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY33847.1 - 1.5e-43 148.0 3.0 2.2e-43 147.5 3.0 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY33847.1 - 4.2e-05 23.4 2.7 9.4e-05 22.3 2.7 1.6 1 1 0 1 1 1 1 Ion channel DUF2182 PF09948.9 CBY33847.1 - 0.16 11.8 1.0 0.24 11.2 1.0 1.4 1 1 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) SH3_1 PF00018.28 CBY33848.1 - 4.4e-05 23.0 0.1 0.00011 21.8 0.1 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY33848.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Kunitz_BPTI PF00014.23 CBY33848.1 - 1.4 9.2 3.1 2 8.7 0.1 2.5 3 0 0 3 3 3 0 Kunitz/Bovine pancreatic trypsin inhibitor domain DOT1 PF08123.13 CBY33849.1 - 5.4e-06 26.1 0.5 9.3e-06 25.3 0.5 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 CBY33849.1 - 0.0038 16.4 0.1 0.0053 16.0 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 CBY33849.1 - 0.0048 16.8 0.3 0.0074 16.2 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY33849.1 - 0.0093 16.7 0.0 0.022 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY33849.1 - 0.034 13.7 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase SNARE PF05739.19 CBY33850.1 - 1.5e-13 50.5 0.4 3.8e-13 49.2 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBY33850.1 - 5.7e-05 22.9 1.0 5.7e-05 22.9 1.0 2.9 2 1 1 3 3 3 1 Syntaxin T3SS_needle_E PF08988.10 CBY33850.1 - 0.00088 19.4 0.1 0.0032 17.6 0.1 2.0 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle ETRAMP PF09716.10 CBY33850.1 - 0.0092 16.0 2.5 0.18 11.8 0.9 2.7 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) MCPsignal PF00015.21 CBY33850.1 - 0.018 14.9 0.8 0.027 14.3 0.1 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3510 PF12022.8 CBY33850.1 - 0.022 15.1 8.7 0.11 12.9 1.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF3510) FlaC_arch PF05377.11 CBY33850.1 - 0.038 14.4 1.7 3 8.3 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3089 PF11288.8 CBY33850.1 - 0.098 12.2 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) TMPIT PF07851.13 CBY33850.1 - 0.18 11.0 9.7 0.15 11.2 7.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein DUF489 PF04356.12 CBY33850.1 - 0.25 11.3 3.9 0.3 11.1 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF489) DUF2779 PF11074.8 CBY33850.1 - 1.8 9.1 9.6 3.4e+02 1.7 9.6 2.7 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) DUF2116 PF09889.9 CBY33850.1 - 8 6.5 5.8 8.4 6.5 1.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DASH_Dam1 PF08653.10 CBY33850.1 - 8.4 6.3 7.9 2.2 8.1 0.9 3.3 3 1 1 4 4 4 0 DASH complex subunit Dam1 PIP5K PF01504.18 CBY33852.1 - 3.8e-40 137.8 3.5 1.1e-32 113.4 0.4 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CBY33852.1 - 2.2e-16 59.6 0.5 4.6e-16 58.5 0.5 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CBY33852.1 - 8.6e-13 48.2 14.1 4.2e-12 46.0 14.1 2.2 1 0 0 1 1 1 1 FYVE zinc finger ACAS_N PF16177.5 CBY33852.1 - 0.033 14.1 0.5 0.11 12.5 0.5 1.9 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus DUF3461 PF11944.8 CBY33852.1 - 0.25 11.4 1.4 0.86 9.7 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3461) NAP PF00956.18 CBY33853.1 - 2.3e-26 92.6 8.7 2.8e-21 75.9 1.2 3.0 1 1 1 3 3 3 3 Nucleosome assembly protein (NAP) Pkinase PF00069.25 CBY33854.1 - 6.7e-58 196.1 0.0 9.9e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33854.1 - 2.1e-40 138.7 0.0 3.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S64 PF08192.11 CBY33854.1 - 0.0047 15.5 4.5 0.0072 14.9 4.5 1.2 1 0 0 1 1 1 1 Peptidase family S64 Cwf_Cwc_15 PF04889.12 CBY33854.1 - 2.8 7.6 11.2 1.1 8.9 8.6 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hus1 PF04005.12 CBY33856.1 - 6.5e-42 143.6 0.1 7.9e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein Aminotran_1_2 PF00155.21 CBY33857.1 - 4.1e-82 276.2 0.0 7.9e-82 275.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3236 PF11576.8 CBY33857.1 - 0.024 14.4 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Pkinase_Tyr PF07714.17 CBY33858.1 - 3.7e-51 173.9 0.0 5.1e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33858.1 - 9.2e-32 110.4 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY33858.1 - 4.9e-10 39.4 0.2 1.2e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 SH2 domain Pkinase_fungal PF17667.1 CBY33858.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SH2_2 PF14633.6 CBY33858.1 - 0.023 14.1 0.0 0.058 12.8 0.0 1.6 1 1 0 1 1 1 0 SH2 domain Kinase-like PF14531.6 CBY33858.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GST_C_2 PF13410.6 CBY33859.1 - 9.4e-07 28.8 0.0 3.7e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBY33859.1 - 2.5e-06 27.7 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY33859.1 - 0.00097 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY33859.1 - 0.018 15.2 0.0 0.039 14.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY33859.1 - 0.038 14.2 0.0 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Sybindin PF04099.12 CBY33860.1 - 1.7e-33 115.5 0.1 1.9e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBY33860.1 - 1.9e-07 31.2 0.0 2.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Band_7 PF01145.25 CBY33862.1 - 0.018 15.0 1.6 0.97 9.4 0.5 2.6 1 1 1 2 2 2 0 SPFH domain / Band 7 family ZYG-11_interact PF05884.12 CBY33862.1 - 0.21 11.0 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Sulfotransfer_1 PF00685.27 CBY33863.1 - 1.1e-07 31.7 0.1 4.1e-07 29.8 0.0 1.7 1 1 0 2 2 2 1 Sulfotransferase domain Esterase_phd PF10503.9 CBY33864.1 - 0.025 14.0 0.1 0.076 12.5 0.1 1.8 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 CBY33864.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold ADK PF00406.22 CBY33865.1 - 1.6e-42 145.2 0.0 1.9e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY33865.1 - 8.4e-19 68.3 0.1 1.4e-18 67.6 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CBY33865.1 - 7e-15 54.7 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CBY33865.1 - 0.092 13.3 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBY33865.1 - 0.092 12.9 0.2 0.47 10.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF4200 PF13863.6 CBY33867.1 - 2.2e-32 111.9 24.8 2.2e-32 111.9 24.8 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF4407 PF14362.6 CBY33867.1 - 7.8 5.8 25.1 8.9e+03 -4.3 25.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CEP63 PF17045.5 CBY33868.1 - 6.7e-09 36.0 23.9 2.9e-05 24.1 0.3 4.1 1 1 3 4 4 4 3 Centrosomal protein of 63 kDa Period_C PF12114.8 CBY33868.1 - 0.12 12.0 2.4 4.9 6.7 0.6 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Tektin PF03148.14 CBY33868.1 - 0.14 10.9 24.1 0.11 11.2 21.3 2.0 1 1 0 1 1 1 0 Tektin family HALZ PF02183.18 CBY33868.1 - 0.41 10.9 14.8 4.2 7.7 2.1 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF812 PF05667.11 CBY33868.1 - 0.45 9.4 23.3 1 8.2 23.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_CLD_2 PF14197.6 CBY33868.1 - 1.3 9.2 19.8 28 4.9 9.7 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Golgin_A5 PF09787.9 CBY33868.1 - 1.7 8.1 20.9 2.5 7.5 0.9 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 TSC22 PF01166.18 CBY33868.1 - 1.8 8.9 11.1 13 6.2 0.2 3.9 3 1 1 4 4 4 0 TSC-22/dip/bun family Spc24 PF08286.11 CBY33868.1 - 2.4 8.5 16.0 3.8 7.8 0.6 3.3 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Rootletin PF15035.6 CBY33868.1 - 2.4 8.1 20.3 1.1 9.2 14.8 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.15 CBY33868.1 - 3.5 7.1 9.0 6.8 6.2 9.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4164 PF13747.6 CBY33868.1 - 9.3 6.6 14.7 0.52 10.6 3.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.19 CBY33868.1 - 9.7 4.0 13.8 13 3.5 13.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3695 PF12494.8 CBY33870.1 - 1.7e-18 66.3 0.4 1e-17 63.8 0.4 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3695) Mito_carr PF00153.27 CBY33871.1 - 2.9e-29 100.8 0.3 1.8e-15 56.6 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial carrier protein PAP2 PF01569.21 CBY33872.1 - 9.7e-20 70.7 3.4 1.6e-19 70.1 3.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CBY33872.1 - 3.6e-10 39.8 1.4 4.9e-10 39.4 0.9 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 CBY33872.1 - 0.0068 16.9 3.8 0.018 15.6 3.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal Amastin PF07344.11 CBY33872.1 - 0.14 12.0 5.5 0.54 10.1 1.8 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein Filament PF00038.21 CBY33873.1 - 0.0028 17.3 12.7 0.0028 17.3 12.7 3.1 1 1 2 3 3 3 2 Intermediate filament protein Csm1_N PF18504.1 CBY33873.1 - 0.026 14.9 1.2 0.026 14.9 1.2 5.5 2 2 4 7 7 7 0 Csm1 N-terminal domain UPF0242 PF06785.11 CBY33873.1 - 0.32 11.1 47.2 0.16 12.1 17.3 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 CBY33873.1 - 0.78 9.8 45.7 0.033 14.2 14.4 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 CBY33873.1 - 1.4 6.4 42.9 16 2.8 43.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 CBY33873.1 - 1.6 8.1 29.6 1.4 8.3 1.4 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4618) DUF1664 PF07889.12 CBY33873.1 - 1.7 8.7 20.1 3.1 7.9 5.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Acyltransferase PF01553.21 CBY33875.1 - 5.8e-07 29.2 0.0 8.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 CBY33875.1 - 2.4e-05 23.4 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-U1 PF06220.12 CBY33876.1 - 3.1e-07 30.0 1.1 5.7e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 U1 zinc finger WW PF00397.26 CBY33876.1 - 3.3e-07 30.3 4.4 3.3e-07 30.3 4.4 2.0 2 0 0 2 2 2 1 WW domain zf-DBF PF07535.12 CBY33876.1 - 0.22 11.7 2.5 0.45 10.7 2.5 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_jaz PF12171.8 CBY33876.1 - 7.4 7.0 8.4 29 5.1 8.4 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 CBY33878.1 - 9.4e-47 157.6 28.1 1e-24 87.0 4.3 2.6 3 0 0 3 3 3 2 CHORD CS PF04969.16 CBY33878.1 - 4.5e-08 34.0 0.1 9.5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.19 CBY33878.1 - 1.2 9.0 17.5 2.1 8.3 0.6 4.0 4 1 0 4 4 4 0 BTK motif RRM_1 PF00076.22 CBY33879.1 - 6.7e-20 70.7 0.0 9.6e-16 57.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBY33879.1 - 0.00086 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.11 CBY33879.1 - 0.0074 16.3 0.1 0.057 13.5 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 CBY33879.1 - 0.034 14.3 0.2 1.2 9.2 0.1 2.8 1 1 1 2 2 2 0 RNA recognition motif DIRP PF06584.13 CBY33879.1 - 0.035 14.3 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 DIRP RRM_5 PF13893.6 CBY33879.1 - 0.049 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 CBY33879.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) PRP38_assoc PF12871.7 CBY33879.1 - 0.24 12.0 14.9 0.44 11.2 14.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_1 PF00076.22 CBY33880.1 - 5.9e-23 80.5 0.1 7.7e-11 41.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBY33880.1 - 8.9e-06 25.7 0.5 0.0014 18.6 0.1 2.3 2 0 0 2 2 2 1 Limkain b1 RRM_occluded PF16842.5 CBY33880.1 - 0.00045 20.0 0.0 0.8 9.6 0.0 2.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY33880.1 - 0.00086 19.3 0.1 0.017 15.1 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY33880.1 - 0.0023 17.5 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY33880.1 - 0.0089 16.0 0.1 1.7 8.7 0.0 2.5 2 1 0 2 2 2 1 DbpA RNA binding domain SET_assoc PF11767.8 CBY33880.1 - 0.044 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PRP38_assoc PF12871.7 CBY33880.1 - 0.66 10.6 55.4 0.05 14.2 33.4 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Connexin PF00029.19 CBY33881.1 - 3.2e-46 158.0 5.8 3.9e-46 157.7 5.8 1.0 1 0 0 1 1 1 1 Connexin Pkinase PF00069.25 CBY33882.1 - 6.3e-38 130.6 0.0 1.3e-37 129.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33882.1 - 2.8e-17 62.9 0.0 3.2e-14 52.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY33882.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY33882.1 - 0.063 12.0 0.0 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 CBY33882.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase dsrm PF00035.26 CBY33883.1 - 0.015 16.0 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Botulinum_HA-17 PF05588.11 CBY33883.1 - 0.06 13.5 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain Ski_Sno PF02437.17 CBY33885.1 - 7.4e-39 131.8 0.1 1.2e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF1366 PF07104.11 CBY33886.1 - 0.02 14.6 2.0 0.03 14.0 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) Jnk-SapK_ap_N PF09744.9 CBY33886.1 - 0.11 12.7 11.4 0.2 11.9 11.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DDE_Tnp_IS66 PF03050.14 CBY33886.1 - 0.17 11.3 4.2 0.26 10.7 4.2 1.2 1 0 0 1 1 1 0 Transposase IS66 family zf-C3HC4_3 PF13920.6 CBY33887.1 - 9e-09 35.1 4.1 2.2e-08 33.8 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY33887.1 - 0.00021 21.1 3.4 0.0014 18.4 3.4 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TLP-20 PF06088.11 CBY33887.1 - 0.0023 17.9 4.1 0.0027 17.6 4.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-RING_2 PF13639.6 CBY33887.1 - 0.042 14.2 1.1 0.042 14.2 1.1 2.6 3 0 0 3 3 3 0 Ring finger domain Tli4_N PF18443.1 CBY33887.1 - 0.051 14.0 1.5 0.093 13.1 1.5 1.4 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain SURF2 PF05477.11 CBY33888.1 - 0.23 11.1 13.0 0.34 10.6 13.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4462 PF14692.6 CBY33889.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) FXa_inhibition PF14670.6 CBY33890.1 - 2.5e-07 30.9 11.5 2.5e-07 30.9 11.5 3.2 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site Sushi PF00084.20 CBY33890.1 - 0.00027 21.5 2.3 0.00027 21.5 2.3 2.1 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) PspB PF06667.12 CBY33891.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.2 4 0 0 4 4 4 0 Phage shock protein B 7TM-7TMR_HD PF07698.11 CBY33891.1 - 1.4 8.7 17.4 0.21 11.3 13.4 1.6 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Sld7_C PF18596.1 CBY33892.1 - 0.02 15.0 0.1 0.053 13.6 0.1 1.7 1 0 0 1 1 1 0 Sld7 C-terminal domain COPIIcoated_ERV PF07970.12 CBY33893.1 - 1.5e-25 90.3 0.2 1e-24 87.6 0.1 2.2 1 1 1 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBY33893.1 - 1.7e-23 82.8 0.2 3.3e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DHDPS PF00701.22 CBY33894.1 - 2.7e-27 95.2 0.0 3.2e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Unstab_antitox PF09720.10 CBY33894.1 - 0.0069 16.4 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative addiction module component DUF1907 PF08925.11 CBY33894.1 - 0.085 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) XFP_C PF09363.10 CBY33894.1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 XFP C-terminal domain DUF5132 PF17195.4 CBY33894.1 - 2.4 8.3 4.6 3.8 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) DS PF01916.17 CBY33895.1 - 4.2e-122 406.9 0.0 4.9e-122 406.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CDC73_N PF16050.5 CBY33896.1 - 3.6e-88 295.7 3.1 5.9e-88 295.0 3.1 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal CDC73_C PF05179.14 CBY33896.1 - 2.3e-44 150.8 3.8 7.1e-44 149.3 2.1 2.5 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal FYVE PF01363.21 CBY33897.1 - 6.2e-18 64.7 10.4 1.2e-17 63.8 10.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger RUN PF02759.19 CBY33897.1 - 5.8e-17 61.9 0.5 1.3e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 RUN domain FYVE_2 PF02318.16 CBY33897.1 - 0.01 16.0 7.1 0.01 16.0 7.1 4.1 2 1 3 6 6 6 0 FYVE-type zinc finger ADK_lid PF05191.14 CBY33897.1 - 0.039 13.9 0.8 0.039 13.9 0.8 1.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid DUF4688 PF15752.5 CBY33897.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) DASH_Hsk3 PF08227.11 CBY33897.1 - 0.33 11.3 8.5 1.2 9.6 0.3 4.0 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like zf-RING_5 PF14634.6 CBY33897.1 - 2.2 8.3 12.0 3.7 7.6 12.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain GPCR_chapero_1 PF11904.8 CBY33899.1 - 2.1e-70 237.6 0.2 3e-70 237.1 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_4 PF13637.6 CBY33899.1 - 1.1e-11 45.0 0.0 3.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY33899.1 - 1.4e-11 44.8 0.0 6.7e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY33899.1 - 1.4e-10 41.1 0.0 9.5e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY33899.1 - 7.9e-10 38.8 0.1 9e-09 35.4 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY33899.1 - 1.6e-09 37.2 0.0 3.4e-05 23.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Phenol_hyd_sub PF06099.11 CBY33899.1 - 0.082 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Phenol hydroxylase subunit GST_C_3 PF14497.6 CBY33901.1 - 3e-16 59.4 0.0 6.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY33901.1 - 2.3e-10 40.7 0.0 4.7e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY33901.1 - 3.6e-08 33.5 0.0 6.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY33901.1 - 0.00061 19.8 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY33901.1 - 0.047 14.4 0.0 0.27 12.0 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain zf-H2C2_2 PF13465.6 CBY33902.1 - 6e-10 39.1 20.0 4.3e-05 23.8 1.1 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY33902.1 - 3.9e-08 33.4 19.3 0.0025 18.5 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY33902.1 - 1.2e-05 25.5 22.1 0.0019 18.5 1.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY33902.1 - 0.027 14.8 17.8 0.087 13.1 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_6 PF18450.1 CBY33902.1 - 0.047 13.4 0.4 0.047 13.4 0.4 2.6 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2_3rep PF18868.1 CBY33902.1 - 0.051 14.2 13.3 0.43 11.3 1.6 3.9 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CBY33902.1 - 0.17 12.3 9.2 0.16 12.4 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 CBY33902.1 - 6.4 6.8 17.6 3.4 7.6 0.6 4.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.12 CBY33902.1 - 9.1 6.6 10.6 27 5.1 2.9 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain SRP_TPR_like PF17004.5 CBY33903.1 - 1.2e-19 70.5 3.0 1.2e-19 70.5 3.0 3.5 4 0 0 4 4 4 1 Putative TPR-like repeat SRP72 PF08492.12 CBY33903.1 - 4e-09 36.8 10.9 4e-09 36.8 10.9 3.0 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_19 PF14559.6 CBY33903.1 - 4e-09 36.8 18.5 0.0043 17.5 0.2 6.8 6 1 2 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY33903.1 - 5.8e-08 32.9 11.6 0.15 12.9 0.3 7.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY33903.1 - 4.7e-07 30.0 14.7 0.02 15.1 0.1 6.0 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY33903.1 - 2.9e-06 27.4 3.9 2.9e-06 27.4 3.9 4.6 6 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBY33903.1 - 3.6e-05 23.6 20.8 0.053 13.7 0.4 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY33903.1 - 0.00074 20.0 10.4 0.77 10.5 0.0 5.9 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY33903.1 - 0.001 19.2 1.9 6.9 6.9 0.0 5.2 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY33903.1 - 0.002 18.0 1.7 0.22 11.6 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY33903.1 - 0.0056 17.3 2.0 8.7 7.1 0.1 5.3 5 1 0 5 5 4 1 Tetratricopeptide repeat ChaB PF06150.12 CBY33903.1 - 0.0097 16.5 0.8 4.3 8.0 0.1 3.2 2 0 0 2 2 2 1 ChaB TPR_1 PF00515.28 CBY33903.1 - 0.012 15.5 13.6 0.82 9.6 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY33903.1 - 0.02 14.8 3.8 2.1 8.3 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY33903.1 - 0.28 10.9 5.8 14 5.4 0.0 5.1 5 0 0 5 5 5 0 TPR repeat Alkyl_sulf_dimr PF14863.6 CBY33903.1 - 2.7 8.4 5.7 8.6 6.8 0.3 3.5 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_8 PF13181.6 CBY33903.1 - 6 7.4 20.9 13 6.3 0.1 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat Pkinase PF00069.25 CBY33904.1 - 1.2e-71 241.2 0.0 2.9e-71 239.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY33904.1 - 5e-44 150.5 0.0 8.2e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBY33904.1 - 3.1e-10 40.5 0.3 1.2e-08 35.3 0.0 2.8 2 1 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBY33904.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBY33904.1 - 0.005 17.5 2.3 0.01 16.5 2.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY33904.1 - 0.044 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Filament PF00038.21 CBY33905.1 - 5.9e-13 49.1 75.5 2.2e-08 34.0 40.5 2.6 2 1 1 3 3 3 2 Intermediate filament protein zf-PARP PF00645.18 CBY33906.1 - 2e-39 134.3 7.8 1.2e-19 71.0 1.3 3.0 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.12 CBY33906.1 - 2.5e-17 62.4 0.3 2.5e-17 62.4 0.3 1.9 2 0 0 2 2 2 1 PADR1 (NUC008) domain Disulph_isomer PF06491.11 CBY33906.1 - 0.17 12.0 0.0 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Disulphide isomerase LRR_8 PF13855.6 CBY33907.1 - 2e-54 181.2 40.6 4.6e-13 48.7 0.2 6.6 3 1 3 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 CBY33907.1 - 6.8e-23 81.0 13.0 3.5e-16 59.3 2.8 3.7 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY33907.1 - 2e-19 69.3 50.6 1.5e-05 25.2 1.1 8.0 1 1 10 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY33907.1 - 1.2e-14 54.2 22.7 4.6e-06 26.2 3.4 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CBY33907.1 - 5.6e-06 26.2 34.2 0.88 10.4 0.1 11.0 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY33907.1 - 1.5e-05 24.7 24.9 0.89 9.8 0.4 9.3 9 0 0 9 9 9 2 Leucine Rich repeat LRRNT PF01462.18 CBY33907.1 - 0.00016 21.3 2.2 0.00016 21.3 2.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 CBY33907.1 - 0.0094 16.4 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain p450 PF00067.22 CBY33908.1 - 1e-48 166.2 0.0 1.2e-48 166.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.20 CBY33909.1 - 5.9e-38 130.8 16.8 6.8e-38 130.6 16.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBY33909.1 - 0.36 10.3 10.0 0.55 9.7 10.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF2244 PF10003.9 CBY33909.1 - 4.7 6.9 6.7 0.58 9.8 0.1 2.4 1 1 0 2 2 2 0 Integral membrane protein (DUF2244) hnRNP_Q_AcD PF18360.1 CBY33911.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Condensation PF00668.20 CBY33912.1 - 7.6e-05 21.6 0.0 0.00023 20.0 0.0 1.8 1 1 0 1 1 1 1 Condensation domain Ras PF00071.22 CBY33914.1 - 5.3e-40 136.7 0.1 6.2e-40 136.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY33914.1 - 2.2e-27 95.6 0.1 3.6e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY33914.1 - 7.3e-12 45.1 0.1 9.2e-12 44.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY33914.1 - 1.8e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY33914.1 - 1.5e-06 28.3 0.0 3.6e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBY33914.1 - 9.7e-05 22.3 0.2 0.06 13.1 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBY33914.1 - 0.00015 21.4 0.5 0.0049 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY33914.1 - 0.00071 19.5 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBY33914.1 - 0.00098 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 CBY33914.1 - 0.0063 16.0 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CBY33914.1 - 0.0087 15.7 0.5 3.4 7.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 CBY33914.1 - 0.016 14.4 0.0 0.038 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CBY33914.1 - 0.026 14.3 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CBY33914.1 - 0.028 13.9 0.1 0.057 12.9 0.1 1.7 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBY33914.1 - 0.051 13.9 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ISP3_C PF18045.1 CBY33914.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ISP3 C-terminal AAA_16 PF13191.6 CBY33914.1 - 0.063 13.7 0.2 0.079 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBY33914.1 - 0.085 12.6 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 CBY33914.1 - 0.13 11.5 0.4 8.8 5.5 0.0 2.1 2 0 0 2 2 2 0 Septin ATPase_2 PF01637.18 CBY33914.1 - 0.16 11.8 2.3 3.9 7.3 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Homeodomain PF00046.29 CBY33915.1 - 5.7e-08 32.5 0.6 6e-08 32.4 0.6 1.0 1 0 0 1 1 1 1 Homeodomain FCH PF00611.23 CBY33916.1 - 0.0034 17.6 0.1 0.0051 17.1 0.1 1.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain 7tm_2 PF00002.24 CBY33917.1 - 9.8e-20 70.9 9.9 1.8e-19 70.0 9.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) HRM PF02793.22 CBY33917.1 - 7.4e-07 29.4 0.2 2.2e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 Hormone receptor domain SUR7 PF06687.12 CBY33917.1 - 0.00012 21.8 0.7 0.00023 20.8 0.7 1.5 1 0 0 1 1 1 1 SUR7/PalI family DUF3328 PF11807.8 CBY33917.1 - 0.44 10.3 3.2 1.6 8.4 3.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Choline_kinase PF01633.20 CBY33918.1 - 1.3e-18 67.4 0.1 3e-17 62.9 0.2 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY33918.1 - 4.6e-09 36.0 0.1 6.6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CBY33918.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY33918.1 - 0.085 12.2 0.0 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY33918.1 - 0.17 11.2 0.2 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain CEP170_C PF15308.6 CBY33919.1 - 0.13 10.7 7.8 0.16 10.5 7.8 1.0 1 0 0 1 1 1 0 CEP170 C-terminus RestrictionMunI PF11407.8 CBY33920.1 - 0.062 13.0 0.9 0.13 12.0 0.7 1.6 2 0 0 2 2 2 0 Type II restriction enzyme MunI Cytochrome_P460 PF16694.5 CBY33920.1 - 0.56 10.6 2.6 0.58 10.5 0.2 2.2 2 0 0 2 2 2 0 Cytochrome P460 Sulfotransfer_4 PF17784.1 CBY33921.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain zf-C2H2 PF00096.26 CBY33922.1 - 1.8e-09 37.5 17.8 0.0018 18.6 3.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY33922.1 - 1.6e-07 31.4 2.2 1.6e-07 31.4 2.2 4.1 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY33922.1 - 2e-06 28.2 18.9 0.0054 17.5 0.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY33922.1 - 2.8e-06 27.5 6.5 0.057 13.8 0.5 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY33922.1 - 0.0035 17.6 11.5 0.21 11.9 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY33922.1 - 1.1 9.6 10.4 4.8 7.6 0.9 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY33922.1 - 9.4 6.4 12.5 5.1 7.2 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger MARVEL PF01284.23 CBY33923.1 - 7.8e-07 29.2 10.5 1.6e-06 28.2 10.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain DctQ PF04290.12 CBY33923.1 - 0.0063 16.4 0.5 0.0063 16.4 0.5 2.0 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Ferric_reduct PF01794.19 CBY33923.1 - 0.019 15.1 4.2 1.6 8.8 4.2 2.4 1 1 0 1 1 1 0 Ferric reductase like transmembrane component TspO_MBR PF03073.15 CBY33923.1 - 0.09 12.8 4.3 0.046 13.8 1.6 1.8 1 1 1 2 2 2 0 TspO/MBR family LIM PF00412.22 CBY33924.1 - 1.5e-44 150.0 52.5 9.2e-12 45.0 1.1 4.1 4 0 0 4 4 4 4 LIM domain DUF5566 PF17721.1 CBY33924.1 - 0.00075 19.8 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5566) Tmemb_55A PF09788.9 CBY33925.1 - 5.1e-31 107.6 12.0 5.9e-31 107.4 12.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 55A zf_UBZ PF18439.1 CBY33925.1 - 0.4 10.3 0.1 0.4 10.3 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF2464 PF10240.9 CBY33926.1 - 4.6e-11 42.8 0.0 4.8e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Multivesicular body subunit 12 Glyco_hydro_6 PF01341.17 CBY33927.1 - 8.1e-07 29.1 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 TMEM125 PF15109.6 CBY33927.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family PAX PF00292.18 CBY33928.1 - 3.9e-69 230.3 0.5 6.3e-69 229.7 0.5 1.3 1 0 0 1 1 1 1 'Paired box' domain Homeodomain PF00046.29 CBY33928.1 - 9.5e-23 79.8 3.8 2.3e-22 78.6 3.8 1.7 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 CBY33928.1 - 8e-05 22.3 1.4 0.00014 21.5 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 CBY33928.1 - 0.00055 20.5 0.3 0.0023 18.5 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_IS1 PF12759.7 CBY33928.1 - 0.005 16.4 0.1 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 InsA C-terminal domain HTH_28 PF13518.6 CBY33928.1 - 0.042 14.0 0.4 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Homeobox_KN PF05920.11 CBY33928.1 - 0.083 12.8 1.2 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain HSF_DNA-bind PF00447.17 CBY33929.1 - 1.5e-17 63.9 1.8 2.8e-17 63.1 1.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1840 PF08895.11 CBY33929.1 - 0.49 10.7 0.0 0.49 10.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 CBY33930.1 - 3.7 7.2 7.7 4.5 6.9 0.2 2.7 2 1 0 2 2 2 0 FAM176 family Vinculin PF01044.19 CBY33932.1 - 1.2e-15 56.9 15.1 1.5e-15 56.6 14.3 1.4 1 1 0 1 1 1 1 Vinculin family KASH_CCD PF14662.6 CBY33932.1 - 0.012 15.5 10.7 0.012 15.5 10.7 3.8 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 CBY33932.1 - 0.016 15.4 10.5 0.016 15.4 10.5 3.9 3 2 1 4 4 4 0 Tropomyosin like Fez1 PF06818.15 CBY33932.1 - 0.23 11.9 33.1 0.24 11.9 24.6 3.3 1 1 2 3 3 3 0 Fez1 FAM76 PF16046.5 CBY33932.1 - 0.49 9.7 21.0 0.017 14.5 13.2 2.2 2 1 0 2 2 2 0 FAM76 protein Fib_alpha PF08702.10 CBY33932.1 - 0.75 10.0 32.1 0.16 12.1 6.5 4.3 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family XRN_M PF17846.1 CBY33932.1 - 1.2 8.0 16.1 0.26 10.2 12.3 1.7 2 0 0 2 2 2 0 Xrn1 helical domain Fmp27_WPPW PF10359.9 CBY33932.1 - 1.4 7.7 24.0 0.26 10.1 19.5 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Nsp1_C PF05064.13 CBY33932.1 - 1.5 8.6 16.8 0.17 11.7 10.4 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.12 CBY33932.1 - 2 8.5 28.7 0.66 10.0 18.7 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 CBY33932.1 - 2.4 8.8 18.1 24 5.7 10.9 4.2 3 1 0 3 3 3 0 SlyX DUF1664 PF07889.12 CBY33932.1 - 2.4 8.2 18.5 0.93 9.5 5.3 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY33932.1 - 3.1 5.6 17.1 5.5 4.8 17.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 CBY33932.1 - 5.3 7.2 26.0 0.038 14.2 14.8 2.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 CBY33932.1 - 9.3 5.5 20.5 1.3 8.4 13.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBY33933.1 - 0.00038 19.4 6.5 0.00054 18.9 6.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CBY33933.1 - 0.0094 16.0 4.7 0.018 15.1 4.7 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation PI_PP_I PF18363.1 CBY33933.1 - 0.036 14.3 1.5 0.08 13.1 1.5 1.6 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain HAUS6_N PF14661.6 CBY33933.1 - 0.041 13.4 5.0 0.063 12.9 5.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.12 CBY33933.1 - 0.042 13.9 5.3 0.086 12.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1759 PF03564.15 CBY33933.1 - 0.049 13.6 3.4 0.096 12.6 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF2730 PF10805.8 CBY33933.1 - 0.1 12.7 3.5 0.23 11.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 CBY33933.1 - 0.16 10.9 2.6 0.17 10.7 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CBY33933.1 - 0.18 9.7 7.3 0.22 9.4 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.6 CBY33933.1 - 0.18 11.9 1.2 0.28 11.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CENP-F_leu_zip PF10473.9 CBY33933.1 - 0.29 11.2 18.3 0.44 10.6 18.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CobN-Mg_chel PF02514.16 CBY33933.1 - 0.31 8.7 4.2 0.39 8.4 4.2 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Atg14 PF10186.9 CBY33933.1 - 1.1 8.3 10.5 1.5 7.9 10.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 CBY33933.1 - 1.1 8.4 9.4 1.6 7.9 9.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seadorna_VP6 PF07407.11 CBY33933.1 - 1.4 7.8 5.8 2 7.3 5.8 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein FapA PF03961.13 CBY33933.1 - 1.8 7.1 9.6 2.2 6.8 9.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 CBY33933.1 - 3.1 8.5 16.4 0.32 11.7 5.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA zf-C4H2 PF10146.9 CBY33933.1 - 8.5 6.6 13.9 13 6.1 13.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein KMP11 PF03037.16 CBY33934.1 - 0.024 15.4 0.9 0.095 13.5 0.8 2.0 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 KIAA1430 PF13879.6 CBY33936.1 - 0.023 15.5 4.6 0.04 14.7 4.6 1.4 1 0 0 1 1 1 0 KIAA1430 homologue SRA1 PF07304.11 CBY33939.1 - 0.17 11.7 0.8 0.6 9.9 0.8 1.9 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Beta_helix PF13229.6 CBY33941.1 - 4.2e-07 29.9 14.9 2.4e-06 27.5 4.0 3.3 2 1 1 3 3 3 2 Right handed beta helix region LRR_8 PF13855.6 CBY33941.1 - 0.00048 19.8 9.0 0.0017 18.1 9.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CBY33941.1 - 1.6 9.2 7.4 3 8.4 6.0 2.3 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF2659 PF10858.8 CBY33942.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) ANAPC3 PF12895.7 CBY33942.1 - 0.04 14.1 1.2 0.065 13.5 1.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Acetyltransf_19 PF18015.1 CBY33943.1 - 0.011 15.9 0.2 0.016 15.4 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MIF4G PF02854.19 CBY33944.1 - 4e-12 46.2 12.7 4e-12 46.2 12.7 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CBY33944.1 - 9.2e-09 35.3 0.4 9.2e-09 35.3 0.4 2.7 3 0 0 3 3 3 1 MA3 domain Ubiquitin_3 PF14836.6 CBY33944.1 - 1 9.4 5.4 3.1 7.8 1.1 3.4 3 0 0 3 3 3 0 Ubiquitin-like domain Adaptin_N PF01602.20 CBY33945.1 - 3.8e-102 342.5 9.1 5.8e-102 341.9 9.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBY33945.1 - 1e-57 193.6 0.0 2.9e-57 192.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBY33945.1 - 8.4e-56 187.8 0.2 8.4e-56 187.8 0.2 2.5 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 CBY33945.1 - 1.2e-11 44.9 9.7 9.6e-08 32.2 0.2 3.5 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY33945.1 - 9.1e-11 42.0 1.2 0.019 15.3 0.0 5.6 3 1 3 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CBY33945.1 - 7.1e-08 32.8 0.9 0.39 11.3 0.0 5.1 4 1 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 CBY33945.1 - 7.2e-08 32.1 0.8 0.13 12.6 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat Coatomer_g_Cpla PF16381.5 CBY33945.1 - 0.00027 21.1 0.2 0.00087 19.4 0.0 1.9 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform Arm PF00514.23 CBY33945.1 - 0.00095 19.1 1.3 0.52 10.4 0.1 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vps16_N PF04841.13 CBY33945.1 - 0.012 14.4 0.2 0.019 13.8 0.2 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region RNA_pol_Rpb1_5 PF04998.17 CBY33945.1 - 0.018 14.5 0.2 0.042 13.3 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Tho2 PF11262.8 CBY33945.1 - 0.07 12.3 1.0 1.1 8.4 0.0 2.7 3 1 0 3 3 3 0 Transcription factor/nuclear export subunit protein 2 eIF3_N PF09440.10 CBY33945.1 - 0.086 13.3 0.5 0.28 11.6 0.2 2.1 2 0 0 2 2 1 0 eIF3 subunit 6 N terminal domain DUF5578 PF17741.1 CBY33945.1 - 0.22 10.9 2.4 3.6 6.9 0.7 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5578) WbqC PF08889.11 CBY33949.1 - 0.0042 17.0 0.3 0.0054 16.7 0.3 1.1 1 0 0 1 1 1 1 WbqC-like protein family DDDD PF10161.9 CBY33950.1 - 4.5e-15 55.2 0.0 5.6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Putative mitochondrial precursor protein Rsm22 PF09243.10 CBY33951.1 - 5e-28 98.2 0.0 1.6e-27 96.5 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CBY33951.1 - 2.4e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY33951.1 - 0.00018 22.1 0.0 0.00061 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY33951.1 - 0.00055 19.8 0.0 0.0099 15.7 0.0 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY33951.1 - 0.003 18.3 0.0 0.011 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY33951.1 - 0.021 15.4 0.0 0.07 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CBY33951.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PDE4_UCR PF18100.1 CBY33952.1 - 0.08 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) MMR_HSR1 PF01926.23 CBY33953.1 - 5.4e-22 78.0 0.0 1.3e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY33953.1 - 1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP1_OBG PF01018.22 CBY33953.1 - 0.00019 21.0 4.3 0.27 10.8 4.5 2.6 2 1 0 2 2 2 2 GTP1/OBG Dynamin_N PF00350.23 CBY33953.1 - 0.0021 18.1 0.5 1 9.4 0.1 3.2 1 1 2 3 3 3 2 Dynamin family AAA_18 PF13238.6 CBY33953.1 - 0.026 15.1 1.0 0.24 11.9 0.0 2.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBY33953.1 - 0.079 13.5 0.9 0.41 11.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 CBY33953.1 - 0.12 11.9 0.1 0.86 9.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBY33953.1 - 0.14 11.1 0.0 0.33 9.9 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FapA PF03961.13 CBY33953.1 - 0.71 8.4 4.2 1.1 7.8 4.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 CBY33953.1 - 0.86 8.6 8.0 50 2.8 8.0 2.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMEM65 PF10507.9 CBY33954.1 - 2e-42 143.5 3.4 2.7e-42 143.1 3.4 1.2 1 0 0 1 1 1 1 Transmembrane protein 65 TMEM131_like PF12371.8 CBY33955.1 - 2.8e-23 82.0 5.7 6.1e-21 74.5 0.2 4.4 5 0 0 5 5 5 2 Transmembrane protein 131-like ASH PF15780.5 CBY33955.1 - 3.7e-11 43.1 0.6 1.9e-08 34.4 0.1 4.3 5 0 0 5 5 5 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY33955.1 - 0.0026 17.6 2.3 0.44 10.4 0.2 3.6 3 0 0 3 3 3 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY33955.1 - 0.0081 16.2 0.4 0.99 9.5 0.0 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) Aconitase PF00330.20 CBY33956.1 - 1.8e-142 475.6 0.0 2.3e-142 475.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CBY33956.1 - 4.5e-43 146.7 0.0 9e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CAP PF00188.26 CBY33957.1 - 3e-13 50.7 0.4 3.8e-13 50.4 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PXA PF02194.15 CBY33957.1 - 0.19 11.7 0.0 0.23 11.4 0.0 1.1 1 0 0 1 1 1 0 PXA domain Phospholip_A2_1 PF00068.19 CBY33958.1 - 2.1e-13 50.7 8.5 2.1e-13 50.7 8.5 2.1 1 1 1 2 2 2 1 Phospholipase A2 Mon1 PF03164.14 CBY33959.1 - 5e-91 305.8 0.2 6e-91 305.5 0.2 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF4258 PF14076.6 CBY33959.1 - 0.05 14.0 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Rotamase_3 PF13616.6 CBY33960.1 - 2.5e-17 63.5 0.0 6.8e-17 62.1 0.0 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CBY33960.1 - 2e-13 51.1 0.1 6.1e-13 49.6 0.1 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Connexin PF00029.19 CBY33961.1 - 3.8e-58 197.0 8.3 6.1e-58 196.3 8.3 1.3 1 1 0 1 1 1 1 Connexin Tho2 PF11262.8 CBY33961.1 - 0.007 15.6 0.7 0.058 12.6 0.2 2.1 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 AAA_17 PF13207.6 CBY33961.1 - 0.094 13.1 3.6 0.14 12.6 3.6 1.2 1 0 0 1 1 1 0 AAA domain Trypsin PF00089.26 CBY33963.1 - 1.3e-12 48.0 1.8 1.9e-12 47.5 1.8 1.2 1 1 0 1 1 1 1 Trypsin Phospholip_A2_1 PF00068.19 CBY33964.1 - 1.5e-13 51.2 7.1 1.5e-13 51.2 7.1 1.9 1 1 0 2 2 2 1 Phospholipase A2 MIP PF00230.20 CBY33965.1 - 2.8e-14 53.4 1.3 3.3e-14 53.1 1.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_9 PF00759.19 CBY33966.1 - 1.4e-130 436.4 14.2 2.3e-130 435.7 14.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM_4_9 PF02018.17 CBY33966.1 - 1.4e-13 51.3 0.6 3.9e-13 49.8 0.6 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain DPBB_1 PF03330.18 CBY33966.1 - 5.9e-08 32.9 0.1 2e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Lytic transglycolase TPR_12 PF13424.6 CBY33966.1 - 0.32 11.3 1.4 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4542 PF15075.6 CBY33967.1 - 0.00016 22.1 0.0 0.00034 21.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) zf-RING_2 PF13639.6 CBY33968.1 - 1.8e-12 47.4 6.4 3.1e-12 46.6 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY33968.1 - 1.8e-09 37.3 7.0 2.8e-09 36.6 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY33968.1 - 5.1e-08 32.8 3.0 7.8e-08 32.2 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBY33968.1 - 1.2e-07 31.3 1.7 2.9e-07 30.1 1.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CBY33968.1 - 1.3e-07 31.4 4.9 2.4e-07 30.5 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY33968.1 - 6.6e-07 29.3 3.1 1.2e-06 28.4 3.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY33968.1 - 5e-06 26.7 8.1 1.5e-05 25.1 8.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY33968.1 - 7.3e-06 25.7 3.3 1.1e-05 25.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY33968.1 - 5.1e-05 22.8 2.6 9.5e-05 21.9 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY33968.1 - 0.0017 18.2 8.2 0.052 13.4 8.5 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 CBY33968.1 - 0.012 15.6 2.6 0.012 15.6 2.6 2.1 2 1 0 2 2 2 0 Zinc-finger RINGv PF12906.7 CBY33968.1 - 0.055 13.6 2.9 0.14 12.3 2.9 1.7 1 1 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 CBY33968.1 - 0.1 12.7 3.5 0.21 11.6 3.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBY33968.1 - 0.22 11.7 2.8 0.56 10.4 2.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CBY33968.1 - 0.4 11.0 5.5 1.2 9.5 5.4 1.8 1 1 1 2 2 2 0 RING-like domain FANCL_C PF11793.8 CBY33968.1 - 0.47 10.7 5.2 3.1 8.1 5.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CBY33968.1 - 0.62 9.9 6.4 1.4 8.7 6.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1351 PF07083.11 CBY33969.1 - 0.0011 18.7 10.1 0.29 10.9 0.1 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF1351) BLOC1_2 PF10046.9 CBY33969.1 - 0.0056 16.9 7.2 1.8 8.9 0.8 3.4 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CBY33969.1 - 0.012 15.7 3.3 0.45 10.5 0.2 3.0 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 CBY33969.1 - 0.07 12.9 3.3 11 5.9 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 HrpB7 PF09486.10 CBY33969.1 - 0.13 12.7 7.5 3.1 8.2 0.1 3.1 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) YabA PF06156.13 CBY33969.1 - 0.14 12.8 11.5 5.2 7.8 1.7 3.3 2 1 1 3 3 3 0 Initiation control protein YabA OAM_alpha PF16552.5 CBY33969.1 - 0.16 11.9 1.1 0.26 11.2 0.2 1.7 2 0 0 2 2 1 0 D-ornithine 4,5-aminomutase alpha-subunit SlyX PF04102.12 CBY33969.1 - 0.17 12.5 6.8 22 5.8 0.0 3.9 3 1 0 3 3 3 0 SlyX DUF724 PF05266.14 CBY33969.1 - 0.19 11.6 10.0 0.029 14.2 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DHR10 PF18595.1 CBY33969.1 - 0.21 11.6 16.0 1.7 8.7 2.0 3.5 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 CBY33969.1 - 0.22 11.6 9.5 4.1 7.5 0.8 3.4 1 1 0 3 3 3 0 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 CBY33969.1 - 0.24 11.3 9.7 0.11 12.4 5.9 2.1 2 1 0 2 2 2 0 STAT protein, all-alpha domain Prominin PF05478.11 CBY33969.1 - 0.36 8.7 8.5 0.25 9.2 3.6 2.0 1 1 1 2 2 2 0 Prominin MerR-DNA-bind PF09278.11 CBY33969.1 - 0.37 11.4 5.3 27 5.4 0.0 4.1 4 0 0 4 4 4 0 MerR, DNA binding ABC_tran_CTD PF16326.5 CBY33969.1 - 0.49 10.7 3.5 48 4.3 0.1 3.5 4 0 0 4 4 3 0 ABC transporter C-terminal domain Sec34 PF04136.15 CBY33969.1 - 0.57 10.1 4.5 0.76 9.7 0.8 2.8 2 1 1 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 CBY33969.1 - 0.6 10.3 13.8 0.088 13.0 4.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 CBY33969.1 - 0.74 9.7 12.9 27 4.7 0.2 4.2 3 1 1 4 4 4 0 Prefoldin subunit DUF4239 PF14023.6 CBY33969.1 - 0.76 9.5 2.3 0.96 9.1 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) NPV_P10 PF05531.12 CBY33969.1 - 0.77 10.3 11.0 4.8 7.7 0.7 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 CBY33969.1 - 0.89 9.9 6.8 9 6.6 0.4 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 CBY33969.1 - 0.92 10.0 9.3 23 5.5 0.3 3.8 3 1 1 4 4 3 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 CBY33969.1 - 0.94 9.9 10.4 13 6.3 0.1 3.9 4 1 1 5 5 4 0 Snapin/Pallidin Nsp1_C PF05064.13 CBY33969.1 - 1.2 9.0 8.6 3.4 7.5 0.8 3.0 3 1 0 3 3 3 0 Nsp1-like C-terminal region Osmo_CC PF08946.10 CBY33969.1 - 1.3 9.3 8.7 3.2 8.1 0.3 3.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil CdvA PF18822.1 CBY33969.1 - 2 8.2 10.8 1.7 8.5 0.1 3.9 4 0 0 4 4 4 0 CdvA-like coiled-coil domain XhlA PF10779.9 CBY33969.1 - 2.2 8.6 11.9 6.6 7.0 0.2 4.3 4 0 0 4 4 4 0 Haemolysin XhlA Ax_dynein_light PF10211.9 CBY33969.1 - 2.4 8.1 14.0 1.4 8.8 3.3 3.3 2 1 1 3 3 3 0 Axonemal dynein light chain Laminin_II PF06009.12 CBY33969.1 - 2.5 8.1 8.4 5.6 7.0 3.6 3.1 1 1 2 3 3 3 0 Laminin Domain II P4Ha_N PF08336.11 CBY33969.1 - 2.8 8.0 7.2 5.9 6.9 0.5 3.4 1 1 3 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4795 PF16043.5 CBY33969.1 - 3.9 7.0 17.9 1.8 8.1 4.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 CBY33969.1 - 8.9 5.5 8.0 4.5 6.4 3.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein HEAT_2 PF13646.6 CBY33970.1 - 0.00059 20.2 3.5 0.11 12.9 0.1 4.5 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CBY33970.1 - 0.011 15.9 5.3 4 7.9 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat RIH_assoc PF08454.11 CBY33970.1 - 0.028 14.3 6.9 1.3 8.9 0.5 3.6 3 0 0 3 3 3 0 RyR and IP3R Homology associated HEAT_EZ PF13513.6 CBY33970.1 - 0.03 14.8 2.4 7.9 7.1 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 CBY33970.1 - 0.057 13.0 1.6 2 7.9 0.2 2.9 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 CBY33970.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 CBY33970.1 - 3.1 8.3 5.0 5 7.6 0.1 3.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain EntA_Immun PF08951.10 CBY33970.1 - 5.8 7.4 7.5 19 5.7 0.4 2.9 2 0 0 2 2 2 0 Enterocin A Immunity PX PF00787.24 CBY33971.1 - 2.7e-05 24.1 0.3 4.5e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 CBY33972.1 - 3.2e-06 27.4 0.0 7.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY33972.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Diacid_rec PF05651.13 CBY33972.1 - 0.052 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative sugar diacid recognition Pkinase_Tyr PF07714.17 CBY33974.1 - 9.9e-75 251.1 0.0 1.1e-73 247.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY33974.1 - 5.3e-31 108.0 0.1 3.1e-30 105.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY33974.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CBY33974.1 - 0.054 12.4 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Sld5 PF05916.11 CBY33975.1 - 5.5e-05 23.6 0.1 9.8e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 CBY33975.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus DUF3879 PF12995.7 CBY33975.1 - 0.096 12.4 0.0 4.4 7.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) SF3b10 PF07189.11 CBY33976.1 - 5.6e-37 125.7 0.0 6.3e-37 125.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Peptidase_S9_N PF02897.15 CBY33977.1 - 1.7e-106 356.5 0.1 2.3e-106 356.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBY33977.1 - 1.5e-58 197.8 0.0 2.7e-58 196.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CBY33977.1 - 0.11 12.4 0.1 0.47 10.3 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CBY33977.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CBY33977.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CENP-C_C PF11699.8 CBY33978.1 - 0.0019 18.4 0.1 0.0061 16.7 0.1 1.9 1 0 0 1 1 1 1 Mif2/CENP-C like PDZ PF00595.24 CBY33979.1 - 1.1e-21 77.0 0.0 3.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY33979.1 - 1.4e-15 56.8 0.2 3.4e-07 30.0 0.0 2.6 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY33979.1 - 4.2e-05 23.8 0.1 0.094 13.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY33979.1 - 0.071 13.1 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.31 CBY33980.1 - 9.4e-16 57.8 30.7 7.7e-08 31.9 20.1 2.3 2 0 0 2 2 2 2 Ion transport protein PMT_4TMC PF16192.5 CBY33980.1 - 4.4 6.9 15.3 2.3 7.8 0.1 3.7 3 1 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase Sulfotransfer_2 PF03567.14 CBY33983.1 - 2.2e-09 37.6 0.2 4.2e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Sulfotransferase family COX4 PF02936.14 CBY33983.1 - 0.063 13.3 0.2 1.3 9.0 0.0 3.0 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV Ndr PF03096.14 CBY33984.1 - 2.1e-64 217.0 0.0 2.6e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 CBY33984.1 - 0.00018 20.8 0.0 0.00059 19.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY33984.1 - 0.00023 20.9 0.0 0.001 18.8 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Fijivirus_P9-2 PF06837.11 CBY33984.1 - 0.06 12.8 0.4 0.49 9.8 0.1 2.0 2 0 0 2 2 2 0 Fijivirus P9-2 protein Ost5 PF05251.12 CBY33985.1 - 2.2e-22 79.1 4.2 2.4e-22 79.0 4.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 HECT PF00632.25 CBY33986.1 - 7.3e-87 291.7 0.0 1.5e-86 290.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW1_helix PF18436.1 CBY33986.1 - 2.2e-06 27.7 3.1 6.1e-06 26.3 3.1 1.8 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 RNA_pol_Rpb5_N PF03871.14 CBY33986.1 - 3.2 8.4 8.1 13 6.5 1.3 3.8 3 2 1 4 4 4 0 RNA polymerase Rpb5, N-terminal domain TPR_8 PF13181.6 CBY33989.1 - 2.3e-15 55.4 9.3 0.12 12.7 0.0 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBY33989.1 - 8.5e-13 47.4 12.6 0.25 11.6 0.1 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY33989.1 - 8.5e-08 31.7 8.1 0.65 9.9 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY33989.1 - 2.7e-07 30.8 4.9 3 8.9 0.0 7.7 9 1 1 10 10 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY33989.1 - 9.5e-07 28.4 1.6 0.012 15.2 0.0 5.7 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 CBY33989.1 - 0.00042 20.8 4.9 20 6.1 0.0 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY33989.1 - 0.00065 19.9 20.3 2.3 8.5 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY33989.1 - 0.0012 18.7 6.6 8.8 6.6 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY33989.1 - 0.022 14.9 0.1 18 5.5 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY33989.1 - 0.046 14.1 4.5 89 3.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 CBY33989.1 - 0.073 13.1 3.6 2.1 8.4 0.3 4.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 CBY33989.1 - 0.17 12.4 10.0 1.9 9.1 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY33989.1 - 0.17 12.1 10.7 27 5.1 0.1 5.2 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Band_7_C PF16200.5 CBY33989.1 - 0.18 11.9 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of band_7 TPR_10 PF13374.6 CBY33989.1 - 1.8 8.5 9.2 15 5.6 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat RPE65 PF03055.15 CBY33990.1 - 3.3e-14 52.9 0.0 3.6e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 CBY33991.1 - 2.4e-39 135.8 0.2 2.9e-39 135.5 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein zf-met PF12874.7 CBY33992.1 - 3e-08 33.8 1.5 5.3e-08 33.0 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY33992.1 - 4.6e-07 29.9 0.4 8.7e-07 29.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RNase_T PF00929.24 CBY33992.1 - 0.00015 22.4 0.0 0.00081 20.0 0.0 2.0 1 1 0 1 1 1 1 Exonuclease zf-C2H2 PF00096.26 CBY33992.1 - 0.012 16.0 0.5 0.012 16.0 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_A_exo1 PF01612.20 CBY33992.1 - 0.014 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease zf-U1 PF06220.12 CBY33992.1 - 0.015 15.1 1.3 0.034 13.9 1.3 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 CBY33992.1 - 0.04 14.8 0.2 0.13 13.2 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger GAGA PF09237.11 CBY33992.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 GAGA factor Tetraspanin PF00335.20 CBY33993.1 - 4.3e-47 160.7 4.0 5e-47 160.5 4.0 1.0 1 0 0 1 1 1 1 Tetraspanin family Neurensin PF14927.6 CBY33993.1 - 0.2 11.4 3.0 0.31 10.7 0.0 2.5 3 0 0 3 3 3 0 Neurensin DUF373 PF04123.13 CBY33993.1 - 0.34 10.3 4.1 0.57 9.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Phage_holin_5_2 PF16079.5 CBY33993.1 - 1 9.8 6.4 0.39 11.1 1.9 2.6 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V SK_channel PF03530.14 CBY33993.1 - 1.8 8.6 4.5 2.2 8.3 0.9 2.5 3 0 0 3 3 3 0 Calcium-activated SK potassium channel PrgI PF12666.7 CBY33993.1 - 7.2 7.4 7.8 0.69 10.7 0.3 2.6 3 0 0 3 3 3 0 PrgI family protein EGF_3 PF12947.7 CBY33995.1 - 8e-46 153.9 90.9 1e-09 38.4 8.6 5.2 5 0 0 5 5 5 5 EGF domain EGF_CA PF07645.15 CBY33995.1 - 4.5e-37 126.0 88.3 8.4e-10 38.7 13.4 6.2 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.7 CBY33995.1 - 3.1e-23 81.4 49.1 5.5e-07 29.4 4.7 5.9 5 0 0 5 5 5 5 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY33995.1 - 4.3e-16 58.7 72.3 1.1e-06 28.6 6.8 6.2 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF PF00008.27 CBY33995.1 - 5.8e-16 58.5 67.9 0.00012 22.3 7.3 6.8 5 2 0 5 5 5 5 EGF-like domain hEGF PF12661.7 CBY33995.1 - 2.3e-07 31.2 74.2 0.00052 20.6 3.2 8.3 8 2 0 8 8 8 5 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY33995.1 - 7.8e-05 22.9 77.1 0.06 13.6 15.2 5.4 4 1 1 5 5 5 5 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY33995.1 - 0.00031 21.0 65.6 0.031 14.6 6.8 6.3 5 1 1 6 6 6 3 Pvs28 EGF domain Dicty_REP PF05086.12 CBY33995.1 - 0.27 9.2 3.1 0.88 7.5 0.2 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 CBY33995.1 - 0.61 10.1 14.4 1.7 8.6 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_C14 PF00656.22 CBY33996.1 - 1.2e-16 61.5 0.0 1.4e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Sporozoite_P67 PF05642.11 CBY33996.1 - 0.11 10.6 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4519 PF15012.6 CBY33996.1 - 0.17 12.0 1.3 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) CUB PF00431.20 CBY33997.1 - 1.1e-11 45.0 0.9 6.5e-10 39.3 0.9 2.5 1 1 0 1 1 1 1 CUB domain Stomoxyn PF11585.8 CBY33997.1 - 1.5 8.9 3.3 0.86 9.7 0.9 1.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Peptidase_M14 PF00246.24 CBY33998.1 - 1.1e-66 225.6 0.6 1.5e-66 225.1 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY33998.1 - 0.00032 21.0 0.1 0.00067 20.0 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide VipB PF05943.12 CBY33999.1 - 0.011 14.5 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath zf-LITAF-like PF10601.9 CBY33999.1 - 0.036 14.3 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain KH_9 PF17904.1 CBY34001.1 - 1.5e-16 60.5 0.2 6.8e-16 58.4 0.2 2.0 2 0 0 2 2 2 1 FMRP KH0 domain KH_1 PF00013.29 CBY34001.1 - 6.9e-12 45.0 0.6 8.5e-07 28.7 0.1 2.8 2 0 0 2 2 2 2 KH domain Agenet PF05641.12 CBY34001.1 - 0.00025 21.5 0.4 0.0014 19.1 0.0 2.4 3 0 0 3 3 3 1 Agenet domain dUTPase PF00692.19 CBY34001.1 - 0.055 13.1 0.1 0.32 10.7 0.0 2.2 2 1 1 3 3 3 0 dUTPase KH_5 PF13184.6 CBY34001.1 - 0.26 11.4 1.5 0.6 10.2 0.2 2.2 3 0 0 3 3 3 0 NusA-like KH domain KH_2 PF07650.17 CBY34001.1 - 0.4 10.5 2.6 11 6.0 0.1 2.8 2 1 1 3 3 3 0 KH domain Pex14_N PF04695.13 CBY34001.1 - 2.3 8.9 9.3 4.2 8.0 9.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Androgen_recep PF02166.16 CBY34001.1 - 4.1 6.2 12.3 6.8 5.4 12.3 1.3 1 0 0 1 1 1 0 Androgen receptor DUF5349 PF17298.2 CBY34001.1 - 6.7 6.4 19.1 11 5.6 19.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) HTH_32 PF13565.6 CBY34003.1 - 0.00015 22.3 3.0 0.089 13.4 0.0 4.2 3 1 1 4 4 4 1 Homeodomain-like domain SCAPER_N PF16501.5 CBY34003.1 - 0.0023 17.9 0.4 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 S phase cyclin A-associated protein in the endoplasmic reticulum LcrG PF07216.12 CBY34003.1 - 0.013 15.4 2.2 0.35 10.8 0.2 2.5 2 0 0 2 2 2 0 LcrG protein HTH_38 PF13936.6 CBY34003.1 - 0.015 15.0 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2999 PF11212.8 CBY34003.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) RasGEF_N PF00618.20 CBY34003.1 - 0.39 11.0 3.6 7.5 6.8 0.2 3.1 3 0 0 3 3 3 0 RasGEF N-terminal motif Pex14_N PF04695.13 CBY34003.1 - 8.5 7.0 15.2 0.49 11.0 3.7 3.2 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Amnionless PF14828.6 CBY34004.1 - 3.6e-05 22.8 0.0 5.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Amnionless FtsX_ECD PF18075.1 CBY34004.1 - 0.62 10.7 3.4 8.3 7.1 0.2 2.6 3 0 0 3 3 3 0 FtsX extracellular domain Aminotran_1_2 PF00155.21 CBY34005.1 - 1.3e-68 231.8 0.0 1.5e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBY34005.1 - 3e-06 26.8 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBY34005.1 - 0.00036 19.6 0.0 0.0005 19.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 CBY34005.1 - 0.00043 19.0 0.0 0.00084 18.1 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.20 CBY34005.1 - 0.0045 15.6 0.0 0.0066 15.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CBY34005.1 - 0.0059 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.7 CBY34005.1 - 0.028 13.2 0.0 0.068 11.9 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase SepSecS PF05889.13 CBY34005.1 - 0.086 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Glyco_transf_7N PF13733.6 CBY34007.1 - 2.1e-47 160.1 9.6 1.1e-22 80.1 0.6 3.3 3 0 0 3 3 3 3 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY34007.1 - 5.3e-42 141.4 8.7 1.5e-20 72.6 1.3 2.6 2 0 0 2 2 2 2 N-terminal domain of galactosyltransferase DUF4500 PF14937.6 CBY34007.1 - 5.5e-05 23.1 0.0 0.4 10.7 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4500) Polysacc_syn_2C PF08485.10 CBY34007.1 - 0.047 13.4 0.3 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal SF3b1 PF08920.10 CBY34007.1 - 0.051 14.1 3.1 6.8 7.2 0.0 3.2 4 0 0 4 4 4 0 Splicing factor 3B subunit 1 VWA PF00092.28 CBY34008.1 - 1.9e-31 109.7 1.5 4e-31 108.6 1.5 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY34008.1 - 6.3e-13 49.3 0.1 1.2e-12 48.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY34008.1 - 1.1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain CUB PF00431.20 CBY34008.1 - 0.00099 19.4 0.2 0.01 16.1 0.1 2.6 2 1 0 2 2 2 1 CUB domain CobT_C PF11775.8 CBY34008.1 - 0.11 12.1 0.1 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain EB PF01683.18 CBY34008.1 - 1.7 9.0 19.9 1 9.7 4.0 3.5 2 1 1 3 3 3 0 EB module TSP_1 PF00090.19 CBY34009.1 - 0.00038 20.6 11.0 0.00038 20.6 11.0 4.0 4 0 0 4 4 4 2 Thrombospondin type 1 domain 7TM_GPCR_Srw PF10324.9 CBY34009.1 - 0.052 12.8 0.3 0.052 12.8 0.3 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF220 PF02713.14 CBY34009.1 - 0.46 10.6 2.5 0.34 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF220 GREB1 PF15782.5 CBY34009.1 - 0.84 6.7 3.0 1.1 6.3 3.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HGTP_anticodon PF03129.20 CBY34010.1 - 0.0039 17.3 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain CagD PF16567.5 CBY34010.1 - 0.022 14.5 0.4 0.03 14.1 0.2 1.2 1 1 0 1 1 1 0 Pathogenicity island component CagD MSC PF09402.10 CBY34010.1 - 0.056 12.9 0.1 0.056 12.9 0.1 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Pkinase PF00069.25 CBY34011.1 - 1.9e-27 96.3 0.1 6.6e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34011.1 - 1.3e-12 47.6 0.0 3.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Nucleocap_ssRNA PF11128.8 CBY34011.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Plant viral coat protein nucleocapsid p450 PF00067.22 CBY34011.1 - 0.064 12.0 0.1 0.13 11.0 0.1 1.4 1 1 0 1 1 1 0 Cytochrome P450 PhoPQ_related PF10142.9 CBY34012.1 - 1.2e-76 257.8 0.2 1.6e-76 257.3 0.2 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Chitin_synth_2 PF03142.15 CBY34013.1 - 2.2e-25 89.3 7.6 2.3e-24 86.0 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY34013.1 - 1.4e-08 34.9 0.0 2.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY34013.1 - 2.3e-07 30.9 9.5 1.6e-06 28.1 8.9 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 TetM_leader PF08076.11 CBY34013.1 - 0.013 15.3 0.6 0.03 14.1 0.6 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide TMF_TATA_bd PF12325.8 CBY34014.1 - 0.0017 18.6 4.8 0.0017 18.6 4.8 25.9 11 4 14 26 26 26 4 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CBY34014.1 - 0.0053 16.8 0.9 0.0053 16.8 0.9 25.0 10 7 16 29 29 29 5 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 CBY34015.1 - 7.9e-61 205.7 0.0 1.3e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34015.1 - 7.6e-24 84.4 0.5 2.2e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34015.1 - 1.2e-09 37.9 0.4 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY34015.1 - 1.7e-07 30.8 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY34015.1 - 0.0052 16.7 0.3 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY34015.1 - 0.026 13.5 0.4 0.61 9.0 0.0 2.3 2 1 0 2 2 2 0 Haspin like kinase domain Reprolysin_3 PF13582.6 CBY34015.1 - 0.05 14.1 0.5 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Choline_kinase PF01633.20 CBY34015.1 - 0.1 12.2 1.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Macoilin PF09726.9 CBY34015.1 - 0.11 11.1 1.4 0.13 10.8 1.4 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 CBY34015.1 - 0.15 10.8 5.3 0.63 8.7 5.3 1.9 1 1 0 1 1 1 0 Fungal protein kinase Mito_fiss_reg PF05308.11 CBY34015.1 - 0.95 9.5 11.7 1.4 8.9 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Na_Pi_cotrans PF02690.15 CBY34016.1 - 9.8e-16 58.1 1.6 1.5e-15 57.5 1.6 1.4 1 0 0 1 1 1 1 Na+/Pi-cotransporter EGF_CA PF07645.15 CBY34017.1 - 6.7e-238 768.8 628.7 1e-11 44.8 10.1 40.4 33 7 7 40 40 40 33 Calcium-binding EGF domain EGF_3 PF12947.7 CBY34017.1 - 5.8e-164 532.0 581.1 7.2e-09 35.7 9.5 41.0 37 3 2 39 39 39 35 EGF domain cEGF PF12662.7 CBY34017.1 - 4.7e-112 365.3 363.3 5.7e-08 32.6 5.3 38.4 38 0 0 38 38 38 34 Complement Clr-like EGF-like hEGF PF12661.7 CBY34017.1 - 4.5e-51 169.9 412.4 0.00015 22.3 7.1 43.3 40 0 0 40 40 40 31 Human growth factor-like EGF EGF PF00008.27 CBY34017.1 - 4.3e-45 151.6 528.6 3.7e-05 23.9 6.6 41.6 40 2 0 40 40 40 30 EGF-like domain EGF_MSP1_1 PF12946.7 CBY34017.1 - 3.5e-25 87.8 462.5 4.1e-06 26.7 2.8 36.5 37 2 0 38 38 38 23 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY34017.1 - 3.6e-11 43.1 533.2 0.021 15.1 6.3 40.2 24 10 16 40 40 40 25 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY34017.1 - 0.00066 19.9 23.2 0.0024 18.2 3.6 37.5 33 6 3 36 36 36 18 Pvs28 EGF domain UNC-93 PF05978.16 CBY34019.1 - 1.6e-22 79.9 7.9 1.6e-22 79.9 7.9 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 SOAR PF16533.5 CBY34019.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF443 PF04276.12 CBY34019.1 - 0.51 10.1 3.8 0.29 10.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Sulfotransfer_2 PF03567.14 CBY34020.1 - 6.8e-17 62.2 1.5 7.9e-17 62.0 1.5 1.1 1 0 0 1 1 1 1 Sulfotransferase family Rubredoxin PF00301.20 CBY34020.1 - 4.1 7.5 5.7 2.2 8.4 0.5 2.3 2 0 0 2 2 2 0 Rubredoxin SUa-2TM PF18179.1 CBY34021.1 - 0.0096 15.3 1.7 0.011 15.1 1.7 1.1 1 0 0 1 1 1 1 SMODS- and Ubiquitin system-associated 2TM effector domain TRIQK PF15168.6 CBY34021.1 - 0.26 11.2 2.0 0.31 11.0 0.6 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family AMP-binding PF00501.28 CBY34022.1 - 5.3e-22 78.0 0.0 6.3e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme zf-CW PF07496.15 CBY34024.1 - 2.3e-14 53.2 3.4 4.2e-14 52.3 3.4 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger PWWP PF00855.17 CBY34024.1 - 6.8e-14 52.1 0.3 2.9e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 PWWP domain AP3D1 PF06375.11 CBY34024.1 - 0.021 15.1 0.9 0.021 15.1 0.9 1.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 zf-C4 PF00105.18 CBY34026.1 - 8.7e-25 87.0 10.9 1.6e-24 86.2 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY34026.1 - 2.6e-09 36.9 0.0 9.5e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Cadherin_3 PF16184.5 CBY34027.1 - 0.0011 19.0 3.9 1.7 8.7 0.0 4.3 5 0 0 5 5 5 2 Cadherin-like Cadherin PF00028.17 CBY34027.1 - 0.0094 16.4 6.0 0.46 11.0 0.0 5.1 5 0 0 5 5 5 1 Cadherin domain Cadherin_C PF01049.17 CBY34027.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 Cadherin cytoplasmic region 7tm_3 PF00003.22 CBY34027.1 - 0.097 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Glyco_transf_7N PF13733.6 CBY34028.1 - 1.9e-45 153.8 0.3 3.3e-45 153.0 0.3 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY34028.1 - 1.2e-20 72.9 0.4 4.8e-20 71.0 0.5 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase BAR PF03114.18 CBY34029.1 - 1.1e-13 51.4 2.2 1.6e-13 50.9 2.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 CBY34029.1 - 6.6e-10 38.7 0.2 1.6e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY34029.1 - 9.5e-07 28.3 0.2 2.6e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY34029.1 - 3e-05 23.6 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HSBP1 PF06825.12 CBY34029.1 - 4.4 7.2 5.9 3 7.8 0.3 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MPS2 PF17060.5 CBY34029.1 - 4.9 6.3 6.8 0.31 10.3 1.9 1.4 2 0 0 2 2 2 0 Monopolar spindle protein 2 Galactosyl_T PF01762.21 CBY34031.1 - 9.9e-30 103.8 0.0 1.4e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase zf-C2H2 PF00096.26 CBY34032.1 - 0.2 12.2 8.4 0.25 11.9 0.0 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY34032.1 - 0.59 11.1 7.2 0.6 11.1 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Collagen PF01391.18 CBY34033.1 - 6.7e-10 38.6 33.0 4.6e-08 32.7 33.0 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) FXa_inhibition PF14670.6 CBY34034.1 - 4.2e-41 138.9 134.7 1.7e-09 37.8 11.7 33.0 11 2 14 25 25 25 8 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 CBY34034.1 - 4.6e-24 84.3 560.0 0.00022 21.3 15.0 30.7 8 6 22 30 30 30 18 Laminin EGF domain cEGF PF12662.7 CBY34034.1 - 2e-23 81.9 52.4 6.8e-08 32.3 0.2 35.4 35 6 5 40 40 40 10 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY34034.1 - 4.1e-23 81.3 83.9 6.3e-10 39.1 5.8 31.7 21 5 9 30 30 30 6 Calcium-binding EGF domain EGF_2 PF07974.13 CBY34034.1 - 0.00042 20.6 37.6 0.0013 19.1 17.4 39.8 29 12 6 35 35 35 11 EGF-like domain EGF PF00008.27 CBY34034.1 - 0.0047 17.2 3.1 0.0047 17.2 3.1 34.9 36 2 0 36 36 36 13 EGF-like domain EGF_3 PF12947.7 CBY34034.1 - 0.01 16.0 10.1 0.01 16.0 10.1 30.3 27 6 0 28 28 28 0 EGF domain Dynein_C PF18199.1 CBY34035.1 - 2e-18 66.7 0.0 2.2e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DUF4916 PF16262.5 CBY34035.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) SspH PF08141.12 CBY34036.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Mobilization_B PF17511.2 CBY34036.1 - 0.1 12.9 0.8 0.18 12.2 0.8 1.4 1 0 0 1 1 1 0 Mobilization protein B YabA PF06156.13 CBY34036.1 - 0.34 11.6 16.5 0.11 13.1 1.6 3.0 1 1 2 3 3 3 0 Initiation control protein YabA Ntox28 PF15605.6 CBY34036.1 - 0.37 11.1 6.1 0.37 11.1 2.4 2.6 1 1 0 2 2 2 0 Bacterial toxin 28 HIP1_clath_bdg PF16515.5 CBY34036.1 - 0.75 10.4 20.9 1.7 9.3 3.7 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 CBY34036.1 - 1.5 9.0 21.3 0.74 9.9 2.2 3.8 3 2 0 3 3 3 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 CBY34036.1 - 1.5 9.0 22.0 5.2e+03 -2.5 22.0 2.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 CBY34036.1 - 2.2 7.6 24.2 0.45 9.8 5.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 CBY34036.1 - 3.1 8.2 16.9 13 6.2 6.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 CBY34036.1 - 3.1 7.8 22.9 83 3.2 18.3 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 CBY34036.1 - 3.4 8.2 25.1 3 8.4 6.4 3.4 2 1 1 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 CBY34036.1 - 4.4 7.3 21.9 22 5.0 3.3 2.9 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion VPS11_C PF12451.8 CBY34036.1 - 6.3 7.1 9.4 8.6 6.7 0.3 3.6 3 1 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal ADIP PF11559.8 CBY34036.1 - 7.7 6.6 21.5 3.6 7.7 12.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LUC7 PF03194.15 CBY34037.1 - 4.2e-73 246.1 15.5 7.2e-73 245.3 15.4 1.5 1 1 0 1 1 1 1 LUC7 N_terminus FidL_like PF15941.5 CBY34037.1 - 0.043 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 FidL-like putative membrane protein DUF1664 PF07889.12 CBY34037.1 - 0.2 11.7 4.9 0.14 12.1 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 CBY34037.1 - 0.22 11.8 4.6 1.5 9.1 0.2 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1043 PF06295.12 CBY34037.1 - 0.85 9.6 4.2 11 6.1 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF16 PF01519.16 CBY34037.1 - 1.2 9.7 7.4 0.26 11.8 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 YtxH PF12732.7 CBY34037.1 - 6.4 7.4 6.2 18 6.0 4.3 2.5 2 1 0 2 2 2 0 YtxH-like protein Transformer PF06495.11 CBY34037.1 - 8.9 6.4 37.4 0.48 10.5 32.0 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein Ribosomal_S21e PF01249.18 CBY34038.1 - 1.1e-37 128.0 0.0 1.2e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ras PF00071.22 CBY34039.1 - 1.1e-19 70.6 0.0 1.4e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY34039.1 - 0.0024 18.1 0.1 0.0059 16.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 CBY34040.1 - 6.2e-30 102.8 0.4 5.3e-12 45.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY34040.1 - 0.011 15.5 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CBY34040.1 - 0.026 14.5 0.2 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 CBY34040.1 - 0.044 13.4 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4921 PF16268.5 CBY34041.1 - 0.099 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) ARL6IP6 PF15062.6 CBY34041.1 - 0.16 12.1 0.2 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Plectin PF00681.20 CBY34043.1 - 0.051 13.4 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Plectin repeat Plectin PF00681.20 CBY34044.1 - 4.3e-106 346.5 14.4 1.3e-14 53.8 0.0 13.3 13 1 1 14 14 14 11 Plectin repeat RAMA PF18755.1 CBY34044.1 - 0.0097 16.3 0.2 3.9 7.9 0.0 4.0 4 0 0 4 4 4 1 Restriction Enzyme Adenine Methylase Associated FANCD2OS PF15124.6 CBY34044.1 - 0.11 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 FANCD2 opposite strand protein I-set PF07679.16 CBY34045.1 - 2.6e-51 171.6 2.7 9.6e-12 44.8 0.0 5.9 4 2 1 5 5 5 5 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY34045.1 - 1.6e-36 124.8 0.0 9.4e-07 29.4 0.0 5.5 4 1 1 5 5 5 5 Immunoglobulin domain Ig_2 PF13895.6 CBY34045.1 - 1.5e-19 70.0 0.0 3.4e-05 24.1 0.0 5.5 4 1 1 5 5 5 4 Immunoglobulin domain ig PF00047.25 CBY34045.1 - 3.1e-16 59.3 0.1 0.019 15.2 0.0 5.7 4 1 1 5 5 5 5 Immunoglobulin domain V-set PF07686.17 CBY34045.1 - 2.5e-05 24.4 0.3 21 5.3 0.0 5.9 5 3 1 6 6 6 1 Immunoglobulin V-set domain Ig_5 PF16681.5 CBY34045.1 - 5.7e-05 23.4 0.4 2.4 8.6 0.0 4.8 5 1 0 5 5 5 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C2-set_2 PF08205.12 CBY34045.1 - 0.00032 20.7 0.1 11 6.1 0.1 4.5 3 1 1 4 4 4 2 CD80-like C2-set immunoglobulin domain CSN8_PSD8_EIF3K PF10075.9 CBY34047.1 - 4.5e-22 78.6 0.0 5.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family WAC_Acf1_DNA_bd PF10537.9 CBY34047.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.7 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Paramyxo_ncap PF00973.19 CBY34048.1 - 3.2 6.6 11.6 3.6 6.4 11.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein L_HMGIC_fpl PF10242.9 CBY34049.1 - 0.00017 21.8 1.9 0.00017 21.8 1.9 2.2 1 1 2 3 3 3 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 CBY34049.1 - 0.0032 17.4 14.0 0.0086 16.0 12.2 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family TMEM37 PF15108.6 CBY34049.1 - 0.023 14.6 0.7 0.056 13.3 0.7 1.8 1 1 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family Clc-like PF07062.12 CBY34049.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 Clc-like DUF4999 PF16390.5 CBY34049.1 - 0.11 12.7 1.8 0.16 12.3 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF4064 PF13273.6 CBY34049.1 - 0.87 9.9 8.6 7.9 6.8 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Phospholip_A2_1 PF00068.19 CBY34050.1 - 1.3e-16 61.0 5.8 1.3e-16 61.0 5.8 1.6 2 0 0 2 2 2 1 Phospholipase A2 LRR_8 PF13855.6 CBY34052.1 - 6.2e-29 99.5 34.1 1.1e-10 41.1 3.2 4.6 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY34052.1 - 1.6e-22 79.2 35.2 1.7e-05 25.1 5.4 5.8 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY34052.1 - 0.00028 20.4 15.8 0.024 14.2 3.0 3.5 1 1 4 5 5 5 5 Leucine-rich repeat EphA2_TM PF14575.6 CBY34052.1 - 0.0044 17.9 0.0 0.0084 17.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CBY34052.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 CBY34052.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRR_1 PF00560.33 CBY34052.1 - 0.3 11.8 28.8 2.2 9.2 1.2 9.3 9 1 0 9 9 9 0 Leucine Rich Repeat DUF3050 PF11251.8 CBY34053.1 - 7.8e-90 300.6 0.0 9.6e-90 300.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Haem_oxygenas_2 PF14518.6 CBY34053.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 Iron-containing redox enzyme Myosin_head PF00063.21 CBY34054.1 - 5e-156 520.7 0.0 5e-156 520.7 0.0 2.3 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY34054.1 - 1.7e-67 228.2 209.7 3.1e-30 104.8 73.1 5.4 1 1 4 5 5 5 5 Myosin tail Myosin_head PF00063.21 CBY34055.1 - 9.3e-84 281.9 0.1 1.1e-83 281.6 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CBY34055.1 - 0.0037 17.5 0.0 0.0071 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY34055.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY34055.1 - 0.077 12.8 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 CBY34055.1 - 0.081 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 CBY34055.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CBY34055.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CBY34055.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kelch_1 PF01344.25 CBY34056.1 - 0.00012 21.6 1.4 0.75 9.4 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY34056.1 - 0.0011 19.0 0.4 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY34056.1 - 0.0032 17.7 0.4 3.6 8.0 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY34056.1 - 0.19 11.8 0.8 7.2 6.8 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Peptidase_M2 PF01401.18 CBY34057.1 - 8e-193 642.1 5.2 9.8e-193 641.8 5.2 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M2 PF01401.18 CBY34058.1 - 3.4e-06 26.0 0.1 4.7e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Angiotensin-converting enzyme PKcGMP_CC PF16808.5 CBY34058.1 - 0.00022 21.0 1.1 0.00034 20.4 1.1 1.3 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 CBY34058.1 - 0.0029 18.2 0.4 0.0046 17.5 0.4 1.3 1 0 0 1 1 1 1 SlyX Fib_alpha PF08702.10 CBY34058.1 - 0.003 17.8 0.1 0.0043 17.2 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CBY34058.1 - 0.026 15.1 0.2 0.036 14.7 0.2 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PspA_IM30 PF04012.12 CBY34058.1 - 0.045 13.3 1.2 0.07 12.7 1.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family Paramyx_P_V_C PF03210.13 CBY34058.1 - 0.065 13.0 0.2 0.091 12.5 0.2 1.1 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Rabaptin PF03528.15 CBY34058.1 - 0.065 11.9 0.1 0.087 11.5 0.1 1.1 1 0 0 1 1 1 0 Rabaptin Csm1_N PF18504.1 CBY34058.1 - 0.12 12.7 1.1 0.18 12.2 1.1 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain Mucin PF01456.17 CBY34059.1 - 0.67 9.9 16.2 1.3 9.0 16.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glycoprotein_G PF00802.19 CBY34060.1 - 0.014 14.8 27.9 0.026 13.9 27.9 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Ndc1_Nup PF09531.10 CBY34060.1 - 0.51 9.0 8.3 0.59 8.7 8.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ferlin_C PF16165.5 CBY34060.1 - 2.3 8.2 5.8 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Mucin PF01456.17 CBY34060.1 - 8.5 6.4 28.4 18 5.3 28.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein TSP_1 PF00090.19 CBY34061.1 - 2.2e-114 373.5 391.9 4.4e-11 42.8 1.6 31.3 29 3 0 29 29 29 27 Thrombospondin type 1 domain Alpha_kinase PF02816.18 CBY34062.1 - 7.6e-51 172.9 0.1 1.8e-50 171.7 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family DUF4512 PF14975.6 CBY34063.1 - 7.8e-18 65.1 15.5 1.1e-16 61.4 15.5 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) Phospholip_A2_1 PF00068.19 CBY34064.1 - 5.2e-13 49.4 1.3 5.2e-13 49.4 1.3 1.7 2 0 0 2 2 2 1 Phospholipase A2 Metallophos PF00149.28 CBY34065.1 - 1.7e-33 116.9 0.0 2.6e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.25 CBY34066.1 - 1.6e-09 37.5 1.4 6e-09 35.6 1.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CBY34066.1 - 2.5e-08 33.7 0.5 6.6e-08 32.3 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CBY34066.1 - 4.5e-07 29.7 0.5 8.9e-07 28.7 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 CBY34066.1 - 0.00073 18.7 0.2 0.0012 18.0 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBY34066.1 - 0.0045 16.9 0.7 0.0062 16.4 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY34066.1 - 0.022 14.2 0.4 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Thioredoxin PF00085.20 CBY34067.1 - 1.4e-28 98.9 0.1 1.6e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBY34067.1 - 3.1e-05 24.1 0.1 4.1e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBY34067.1 - 0.00086 18.7 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY34067.1 - 0.0012 19.3 0.4 0.024 15.1 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY34067.1 - 0.0046 16.9 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY34067.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 CBY34067.1 - 0.053 13.7 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Amidohydro_2 PF04909.14 CBY34067.1 - 0.081 12.7 0.1 0.082 12.7 0.1 1.0 1 0 0 1 1 1 0 Amidohydrolase Thioredoxin_9 PF14595.6 CBY34067.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Mito_carr PF00153.27 CBY34068.1 - 1.9e-43 146.3 6.5 5.8e-18 64.6 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Collagen PF01391.18 CBY34069.1 - 9.7e-18 63.7 57.1 6.9e-09 35.3 28.1 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY34069.1 - 5.6e-11 43.0 0.9 8e-11 42.5 0.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY34069.1 - 0.0011 19.5 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.25 CBY34070.1 - 1.5e-67 227.8 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34070.1 - 4.8e-43 147.3 0.0 5.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34070.1 - 4.3e-08 32.8 0.0 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY34070.1 - 0.005 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY34070.1 - 0.059 12.3 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBY34070.1 - 0.067 12.8 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 CBY34071.1 - 1.6e-21 76.2 0.0 8.3e-07 29.6 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34071.1 - 1.7e-09 37.8 0.0 0.00018 21.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 CBY34071.1 - 0.16 10.6 0.0 0.38 9.3 0.0 1.6 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Proteasome_A_N PF10584.9 CBY34071.1 - 0.21 11.3 0.6 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Katanin_con80 PF13925.6 CBY34072.1 - 2.2e-09 37.6 0.1 3.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 con80 domain of Katanin GFO_IDH_MocA PF01408.22 CBY34073.1 - 5.1e-20 72.5 0.0 7.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pkinase PF00069.25 CBY34075.1 - 1.5e-67 227.8 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34075.1 - 4.8e-43 147.3 0.0 5.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34075.1 - 4.3e-08 32.8 0.0 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY34075.1 - 0.005 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY34075.1 - 0.059 12.3 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBY34075.1 - 0.067 12.8 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 CBY34076.1 - 1.8e-20 72.8 0.1 1.5e-06 28.8 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Katanin_con80 PF13925.6 CBY34076.1 - 6.2e-16 58.8 0.1 1e-15 58.2 0.1 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 CBY34076.1 - 8.7e-09 35.6 0.0 0.00033 20.9 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GFO_IDH_MocA PF01408.22 CBY34077.1 - 5.1e-20 72.5 0.0 7.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ASH PF15780.5 CBY34078.1 - 8e-21 74.1 2.3 2.9e-10 40.2 0.0 8.1 8 1 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBY34078.1 - 5.3e-10 39.4 1.3 0.026 14.7 0.0 5.4 6 0 0 6 6 6 3 Flagellar-associated PapD-like TMEM131_like PF12371.8 CBY34078.1 - 5.4e-10 39.4 2.1 0.086 13.1 0.1 6.3 6 1 0 6 6 6 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBY34078.1 - 9.6e-06 25.4 1.4 2.7 7.9 0.1 6.4 6 1 0 6 6 6 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY34078.1 - 0.0019 18.2 0.6 24 5.1 0.0 5.7 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) Securin PF04856.13 CBY34078.1 - 0.14 12.1 5.0 0.049 13.6 1.3 2.0 1 1 1 2 2 2 0 Securin sister-chromatid separation inhibitor Connexin PF00029.19 CBY34079.1 - 1.3e-54 185.4 3.4 1.5e-54 185.3 3.4 1.0 1 0 0 1 1 1 1 Connexin Pro_racemase PF05544.11 CBY34080.1 - 0.037 13.1 0.0 0.039 13.0 0.0 1.0 1 0 0 1 1 1 0 Proline racemase PAN_1 PF00024.26 CBY34081.1 - 8.9e-16 57.6 11.4 4.8e-05 23.2 0.9 3.5 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 CBY34081.1 - 5.7e-05 22.9 10.8 0.0071 16.2 0.1 3.5 3 0 0 3 3 3 3 PAN domain DUF1759 PF03564.15 CBY34081.1 - 0.074 13.0 1.0 0.13 12.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) FUSC PF04632.12 CBY34081.1 - 0.84 8.1 7.5 1.1 7.7 7.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sbi-IV PF11621.8 CBY34081.1 - 1.3 9.4 4.9 12 6.4 0.0 3.5 3 0 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI TMEM43 PF07787.12 CBY34081.1 - 5.5 6.3 9.8 25 4.1 9.8 1.9 1 1 0 1 1 1 0 Transmembrane protein 43 CBM_14 PF01607.24 CBY34082.1 - 3.6e-11 43.1 5.2 3.6e-11 43.1 5.2 1.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Histone PF00125.24 CBY34083.1 - 0.019 15.3 0.1 0.046 14.1 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY34083.1 - 0.075 13.3 0.1 2 8.8 0.0 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lectin_C PF00059.21 CBY34084.1 - 1.9e-40 137.9 17.2 2.4e-16 60.4 0.8 3.7 4 0 0 4 4 4 3 Lectin C-type domain Trefoil PF00088.18 CBY34084.1 - 1.9e-08 34.0 4.5 5e-08 32.7 4.5 1.8 1 0 0 1 1 1 1 Trefoil (P-type) domain EF-hand_14 PF17959.1 CBY34085.1 - 0.085 13.2 0.0 0.091 13.1 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain NPV_P10 PF05531.12 CBY34086.1 - 0.014 15.8 0.4 0.018 15.5 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YgaB PF14182.6 CBY34086.1 - 0.041 14.3 3.8 0.056 13.8 3.8 1.3 1 0 0 1 1 1 0 YgaB-like protein Serpin PF00079.20 CBY34087.1 - 7.4e-56 190.0 0.1 1.3e-55 189.3 0.1 1.3 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) 2OG-FeII_Oxy PF03171.20 CBY34089.1 - 1.9e-15 57.2 0.0 3.4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAM PF00629.23 CBY34090.1 - 2.9e-23 82.5 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Phospholip_A2_1 PF00068.19 CBY34091.1 - 0.00082 19.8 0.1 0.00082 19.8 0.1 1.9 2 1 0 2 2 2 1 Phospholipase A2 YqzE PF14038.6 CBY34091.1 - 0.27 11.2 3.0 0.4 10.7 2.2 1.7 2 0 0 2 2 2 0 YqzE-like protein Trypsin PF00089.26 CBY34092.1 - 1.4e-31 110.0 0.8 3.4e-31 108.8 0.2 1.9 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY34092.1 - 5.5e-14 52.4 0.4 4.1e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 CUB domain Ammonium_transp PF00909.21 CBY34093.1 - 1e-60 205.5 17.4 1.1e-60 205.4 17.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG2 PF06148.11 CBY34094.1 - 0.012 15.7 0.4 0.025 14.7 0.4 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.16 CBY34095.1 - 2.2e-36 125.5 23.4 2.2e-36 125.5 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY34095.1 - 3.5e-12 45.9 7.0 6.8e-12 45.0 7.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CBY34095.1 - 7e-10 37.8 12.1 8.7e-07 27.6 1.0 3.4 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CBY34095.1 - 0.00017 20.3 19.3 0.00022 19.9 6.6 3.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 CBY34095.1 - 0.0019 16.7 1.2 0.0019 16.7 1.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector HisKA_4TM PF16926.5 CBY34095.1 - 0.36 10.4 2.4 0.33 10.5 0.7 1.8 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase Acid_PPase PF12689.7 CBY34096.1 - 3.9e-34 117.9 2.7 8e-27 94.1 0.1 2.0 1 1 1 2 2 2 2 Acid Phosphatase Cystatin PF00031.21 CBY34098.1 - 9.5e-08 32.2 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain ACPS PF01648.20 CBY34099.1 - 6.6e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Period_C PF12114.8 CBY34100.1 - 0.072 12.7 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Desmo_N PF06771.11 CBY34100.1 - 0.09 13.1 0.2 21 5.6 0.0 2.9 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus SHMT PF00464.19 CBY34101.1 - 1.3e-184 613.5 0.0 1.5e-184 613.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 CBY34101.1 - 0.026 13.9 0.4 0.076 12.3 0.3 1.8 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CBY34101.1 - 0.032 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II SET PF00856.28 CBY34102.1 - 3.4e-16 60.1 1.0 1.3e-15 58.1 0.1 2.5 2 1 0 2 2 2 1 SET domain Chromo PF00385.24 CBY34102.1 - 5e-05 23.1 0.3 0.00019 21.3 0.3 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COG6 PF06419.11 CBY34103.1 - 2.8e-171 570.9 16.2 3.3e-171 570.7 16.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec34 PF04136.15 CBY34103.1 - 0.0025 17.7 3.7 0.0084 16.0 2.5 2.6 2 0 0 2 2 2 1 Sec34-like family MCC-bdg_PDZ PF10506.9 CBY34103.1 - 0.064 13.3 1.0 0.33 11.0 1.0 2.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome OmpH PF03938.14 CBY34103.1 - 0.065 13.6 4.8 0.1 12.9 4.0 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Cas_DxTHG PF09455.10 CBY34103.1 - 0.11 12.0 4.5 0.24 10.9 4.5 1.6 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family APG6_N PF17675.1 CBY34103.1 - 0.12 12.9 3.6 0.39 11.3 3.6 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 CBY34103.1 - 0.13 11.1 4.5 0.2 10.5 4.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4164 PF13747.6 CBY34103.1 - 0.13 12.5 3.0 0.25 11.6 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 CBY34103.1 - 0.15 12.2 4.2 0.57 10.4 2.1 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CBY34103.1 - 0.17 12.6 4.5 0.63 10.8 1.7 3.1 3 0 0 3 3 3 0 Occludin homology domain DASH_Dad3 PF08656.10 CBY34103.1 - 0.18 11.9 3.1 0.27 11.3 0.6 2.7 2 0 0 2 2 1 0 DASH complex subunit Dad3 Mod_r PF07200.13 CBY34103.1 - 0.42 10.7 11.1 6.4 6.9 4.6 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 CBY34103.1 - 0.49 10.4 6.9 2.6 8.1 1.8 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 CBY34103.1 - 0.53 10.7 5.4 3.5 8.1 5.5 2.6 1 1 0 1 1 1 0 Syntaxin-like protein CHASE3 PF05227.13 CBY34103.1 - 0.87 9.5 6.6 0.24 11.3 1.2 2.7 2 1 1 3 3 3 0 CHASE3 domain SHE3 PF17078.5 CBY34103.1 - 6.1 6.5 11.0 0.096 12.4 0.8 2.9 3 1 0 4 4 4 0 SWI5-dependent HO expression protein 3 Prenyltrans PF00432.21 CBY34104.1 - 1.6e-42 142.9 0.9 4.3e-11 42.3 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CBY34104.1 - 0.00099 18.3 0.0 0.44 9.6 0.0 2.5 2 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBY34104.1 - 0.0024 17.0 0.0 0.023 13.8 0.0 2.1 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain EFG_II PF14492.6 CBY34104.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II Per1 PF04080.13 CBY34106.1 - 0.097 12.4 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Per1-like family Sde2_N_Ubi PF13019.6 CBY34108.1 - 5.4e-19 68.6 1.4 5.4e-19 68.6 1.4 2.4 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 CBY34108.1 - 7.4e-19 67.2 0.3 2.2e-18 65.7 0.1 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Nucleoporin_N PF08801.11 CBY34109.1 - 0.034 12.9 0.2 0.1 11.4 0.1 1.8 1 1 0 1 1 1 0 Nup133 N terminal like SURF1 PF02104.15 CBY34110.1 - 0.065 13.5 0.0 0.082 13.2 0.0 1.1 1 0 0 1 1 1 0 SURF1 family DUF1970 PF09301.10 CBY34110.1 - 0.099 12.9 0.1 0.15 12.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) Proton_antipo_M PF00361.20 CBY34110.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter Miga PF10265.9 CBY34111.1 - 3.5e-61 207.8 0.4 4.7e-61 207.4 0.4 1.1 1 0 0 1 1 1 1 Mitoguardin PMG PF05287.12 CBY34111.1 - 0.035 14.1 4.1 1.5 8.8 2.0 2.4 2 0 0 2 2 2 0 PMG protein Lipocalin_7 PF14651.6 CBY34113.1 - 1.3e-13 51.0 0.4 1.4e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1521 PF07481.11 CBY34113.1 - 0.029 14.4 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) EGF_3 PF12947.7 CBY34114.1 - 3.3e-50 168.0 376.7 4.8e-08 33.1 8.1 23.8 22 1 1 23 23 23 17 EGF domain EGF_CA PF07645.15 CBY34114.1 - 2.6e-17 62.7 103.0 1.3e-08 34.9 10.0 23.7 18 4 6 24 24 24 10 Calcium-binding EGF domain EGF PF00008.27 CBY34114.1 - 2.8e-11 43.5 347.0 0.00051 20.3 10.0 25.3 22 3 1 24 24 24 17 EGF-like domain EGF_MSP1_1 PF12946.7 CBY34114.1 - 0.0002 21.3 31.9 0.00022 21.2 12.3 22.7 23 0 0 23 23 23 14 MSP1 EGF domain 1 hEGF PF12661.7 CBY34114.1 - 0.00035 21.1 15.5 0.0019 18.7 3.6 27.0 24 2 0 24 24 24 11 Human growth factor-like EGF cEGF PF12662.7 CBY34114.1 - 0.00089 19.1 224.1 0.053 13.5 5.5 23.7 22 1 1 23 23 23 15 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY34114.1 - 0.0096 16.2 1.3 0.0096 16.2 1.3 23.8 23 1 0 23 23 23 7 Pvs28 EGF domain Dickkopf_N PF04706.12 CBY34115.1 - 9.1e-15 54.9 36.1 1.4e-12 47.9 20.2 2.7 2 1 0 2 2 2 2 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 CBY34115.1 - 0.26 11.7 35.4 0.064 13.6 19.9 2.9 2 2 0 2 2 2 0 UPF0506 FAM217 PF15344.6 CBY34115.1 - 7 6.5 13.2 3.1 7.7 10.7 1.6 1 1 0 1 1 1 0 FAM217 family Zona_pellucida PF00100.23 CBY34116.1 - 1.5e-06 28.2 0.6 2.9e-06 27.3 0.6 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain Ig_3 PF13927.6 CBY34117.1 - 2.3e-15 57.0 1.3 1.7e-11 44.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY34117.1 - 1.4e-12 47.8 0.2 7.5e-07 29.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY34117.1 - 2e-09 37.4 0.4 2.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 CBY34117.1 - 2.6e-09 37.1 0.1 4.7e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY34117.1 - 4.5e-05 23.2 0.2 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 V-set PF07686.17 CBY34117.1 - 0.00017 21.7 0.9 0.032 14.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.11 CBY34117.1 - 0.0084 16.2 0.8 0.013 15.6 0.1 1.6 2 0 0 2 2 2 1 Podoplanin C2-set_2 PF08205.12 CBY34117.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY34117.1 - 0.092 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain PMP1_2 PF08114.11 CBY34117.1 - 1.1 9.1 3.7 0.35 10.7 0.7 1.7 2 0 0 2 2 2 0 ATPase proteolipid family EGF_CA PF07645.15 CBY34118.1 - 2.8e-70 232.3 187.1 7.8e-09 35.6 6.4 15.4 15 0 0 15 15 15 12 Calcium-binding EGF domain EGF_3 PF12947.7 CBY34118.1 - 6.1e-27 93.5 152.4 3.6e-07 30.3 4.3 16.1 13 3 2 15 15 15 12 EGF domain FXa_inhibition PF14670.6 CBY34118.1 - 2.2e-10 40.6 138.9 0.01 16.1 2.8 14.5 12 3 1 13 13 13 10 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY34118.1 - 2.9e-10 39.9 118.8 0.00052 19.9 0.9 16.2 14 2 0 14 14 14 9 Complement Clr-like EGF-like hEGF PF12661.7 CBY34118.1 - 1.4e-06 28.7 27.1 7e-05 23.3 5.4 17.5 19 2 1 20 20 20 10 Human growth factor-like EGF Ank_5 PF13857.6 CBY34120.1 - 5.7e-13 48.8 0.0 3.9e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY34120.1 - 7.1e-11 42.5 0.1 3.6e-06 27.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY34120.1 - 1.3e-10 41.6 1.1 4.9e-06 27.0 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY34120.1 - 1.6e-08 34.1 0.0 0.001 19.3 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CBY34120.1 - 2.4e-08 34.1 0.1 0.2 12.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat PT-VENN PF04829.13 CBY34121.1 - 0.024 14.7 8.8 12 6.0 0.1 4.7 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif DUF1281 PF06924.11 CBY34121.1 - 0.91 9.0 16.9 2.3 7.7 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1281) Sigma_1s PF02454.16 CBY34121.1 - 3.2 7.8 12.7 5.4 7.0 0.1 4.7 5 0 0 5 5 5 0 Sigma 1s protein PT-VENN PF04829.13 CBY34122.1 - 0.071 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif EF-hand_7 PF13499.6 CBY34123.1 - 0.0026 18.2 5.2 0.0034 17.8 0.1 3.5 2 2 0 2 2 2 1 EF-hand domain pair HMG_box_2 PF09011.10 CBY34123.1 - 0.017 15.7 14.9 0.1 13.2 1.1 3.2 3 0 0 3 3 3 0 HMG-box domain EF-hand_6 PF13405.6 CBY34123.1 - 0.075 13.0 0.0 3 8.0 0.0 3.1 2 0 0 2 2 2 0 EF-hand domain PCMD PF13201.6 CBY34123.1 - 0.14 11.9 0.9 0.32 10.8 0.1 2.0 2 0 0 2 2 2 0 Putative carbohydrate metabolism domain HMG_box PF00505.19 CBY34123.1 - 0.47 10.9 10.9 4.1 7.9 2.0 3.5 2 0 0 2 2 2 0 HMG (high mobility group) box PT-VENN PF04829.13 CBY34123.1 - 0.56 10.3 3.3 3.7 7.7 0.2 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif GST_N_4 PF17172.4 CBY34123.1 - 0.84 10.4 7.7 3 8.7 0.3 3.7 3 1 0 3 3 3 0 Glutathione S-transferase N-terminal domain DUF5341 PF17276.2 CBY34123.1 - 0.9 9.7 3.8 29 4.8 0.1 3.0 1 1 0 2 2 2 0 Family of unknown function (DUF5341) DZR PF12773.7 CBY34124.1 - 1 9.4 13.1 0.27 11.3 8.9 2.2 2 0 0 2 2 2 0 Double zinc ribbon 7tm_1 PF00001.21 CBY34127.1 - 4.3e-07 29.5 0.1 4.3e-07 29.5 0.1 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Atthog PF18800.1 CBY34127.1 - 0.066 13.1 0.8 0.073 13.0 0.8 1.0 1 0 0 1 1 1 0 Attenuator of Hedgehog HA2 PF04408.23 CBY34129.1 - 1.1e-25 90.0 0.5 5.5e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY34129.1 - 2e-23 82.6 0.0 4.2e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBY34129.1 - 1.5e-13 51.1 0.0 6.5e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBY34129.1 - 3.4e-06 27.4 0.1 8.6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY34129.1 - 7.4e-06 25.8 1.2 2e-05 24.4 1.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBY34129.1 - 0.0012 19.1 0.2 0.0037 17.6 0.2 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBY34129.1 - 0.0027 16.8 0.1 0.0071 15.4 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBY34129.1 - 0.0028 17.4 0.1 0.0061 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY34129.1 - 0.022 14.8 0.5 0.21 11.6 0.5 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBY34129.1 - 0.048 13.1 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CBY34129.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CBY34129.1 - 0.078 13.5 0.3 1.4 9.4 0.2 2.6 1 1 0 2 2 2 0 ABC transporter SRP54 PF00448.22 CBY34129.1 - 0.078 12.6 0.3 0.21 11.2 0.3 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBY34129.1 - 0.089 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 CBY34129.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBY34129.1 - 0.17 11.6 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 CBY34129.1 - 0.4 11.1 1.5 2.1 8.8 0.6 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) EF-hand_6 PF13405.6 CBY34130.1 - 0.0038 17.0 0.1 0.21 11.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBY34130.1 - 0.007 15.8 0.0 1.5 8.6 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 CBY34130.1 - 0.013 15.9 0.1 0.79 10.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_4 PF12763.7 CBY34130.1 - 0.12 12.3 0.1 1.5 8.8 0.0 2.4 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.16 CBY34131.1 - 2.8e-56 190.9 15.9 7.8e-55 186.2 15.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY34131.1 - 1.6e-06 27.2 0.5 1.6e-06 27.2 0.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 CBY34131.1 - 0.00016 20.4 11.7 0.014 14.0 0.3 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 CBY34131.1 - 0.0022 16.9 5.2 0.0022 16.9 5.2 2.0 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 CBY34131.1 - 0.0071 15.7 5.7 0.013 14.9 5.7 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 CBY34131.1 - 0.031 14.6 3.5 2.2 8.6 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF1279 PF06916.13 CBY34131.1 - 0.05 14.2 0.0 5.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) Mucin PF01456.17 CBY34132.1 - 0.01 15.8 17.8 0.012 15.6 17.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC2_membrane_3 PF12698.7 CBY34132.1 - 0.14 11.3 1.7 0.25 10.4 1.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Plasmodium_Vir PF05795.11 CBY34132.1 - 0.29 10.5 1.0 0.31 10.4 1.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-C3HC4_3 PF13920.6 CBY34133.1 - 9e-08 31.9 7.8 9e-08 31.9 7.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY34133.1 - 1.9e-06 27.7 9.5 1.9e-06 27.7 9.5 3.1 4 0 0 4 4 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY34133.1 - 2.8e-06 27.6 11.0 2.8e-06 27.6 11.0 2.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_4 PF14570.6 CBY34133.1 - 2.5e-05 23.9 7.9 2.5e-05 23.9 7.9 3.1 3 1 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY34133.1 - 6.4e-05 22.7 11.4 6.4e-05 22.7 11.4 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY34133.1 - 0.00011 22.0 8.1 0.00011 22.0 8.1 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY34133.1 - 0.00069 19.4 11.7 0.00069 19.4 11.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY34133.1 - 0.0011 19.0 7.5 0.0011 19.0 7.5 3.1 2 2 1 3 3 3 1 RING-type zinc-finger DUF1272 PF06906.11 CBY34133.1 - 0.0098 16.0 6.3 0.0098 16.0 6.3 2.7 2 1 1 3 3 2 1 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 CBY34133.1 - 0.039 13.7 4.4 0.17 11.7 4.4 2.2 1 0 0 1 1 1 0 RING-like zinc finger DUF2256 PF10013.9 CBY34133.1 - 0.28 11.3 0.3 0.28 11.3 0.3 4.2 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C3HC4_4 PF15227.6 CBY34133.1 - 1.9 8.7 22.2 0.1 12.8 8.1 3.6 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING Elf1 PF05129.13 CBY34133.1 - 3.1 7.9 21.8 1.4 9.0 2.9 4.2 3 2 1 4 4 4 0 Transcription elongation factor Elf1 like FA_hydroxylase PF04116.13 CBY34134.1 - 2.7e-27 95.7 13.5 2.7e-27 95.7 13.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cullin PF00888.22 CBY34135.1 - 8.9e-207 688.5 28.8 1.2e-206 688.1 28.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY34135.1 - 2.7e-29 101.0 0.9 1e-28 99.1 0.9 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 CBY34135.1 - 3.7 8.1 7.6 0.82 10.2 0.1 3.5 3 1 1 4 4 4 0 ATP-utilising chromatin assembly and remodelling N-terminal Glyco_hydro_4C PF11975.8 CBY34135.1 - 5.1 7.1 8.5 5.6 7.0 1.7 3.3 3 1 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain EF-hand_6 PF13405.6 CBY34136.1 - 1.7e-14 52.4 15.0 1.6e-05 24.5 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 CBY34136.1 - 3.2e-14 51.3 11.5 1.9e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY34136.1 - 1.7e-13 50.8 5.5 5.6e-07 29.9 1.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY34136.1 - 5.7e-07 28.7 7.1 0.0093 15.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY34136.1 - 5.2e-05 23.0 11.8 0.00021 21.0 1.4 3.9 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY34136.1 - 0.00011 22.5 0.2 1.8 9.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain Ras PF00071.22 CBY34137.1 - 1.1e-46 158.4 0.6 1.4e-46 158.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY34137.1 - 5.2e-11 42.8 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY34137.1 - 1.6e-05 24.5 0.1 1.9e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY34137.1 - 0.0006 19.8 0.1 0.00087 19.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CBY34137.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CBY34137.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Big_3_2 PF12245.8 CBY34137.1 - 0.052 13.8 0.0 0.31 11.3 0.0 2.0 1 1 1 2 2 2 0 Bacterial Ig-like domain AlkA_N PF06029.11 CBY34137.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 AlkA N-terminal domain LysM PF01476.20 CBY34138.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Plasmod_dom_1 PF09715.10 CBY34138.1 - 0.056 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) SET PF00856.28 CBY34139.1 - 4.7e-19 69.4 0.1 1.9e-18 67.4 0.1 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CBY34139.1 - 6.1e-17 62.2 13.1 6.1e-17 62.2 13.1 3.1 3 0 0 3 3 3 1 Pre-SET motif Metallothio_2 PF01439.18 CBY34139.1 - 0.033 15.1 4.7 0.033 15.1 4.7 3.6 4 0 0 4 4 4 0 Metallothionein Ank_2 PF12796.7 CBY34140.1 - 0.014 16.0 0.0 0.048 14.2 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY34140.1 - 0.04 14.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Amino_oxidase PF01593.24 CBY34141.1 - 1.2e-14 54.5 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 CBY34141.1 - 1.2e-13 51.2 0.7 2.8e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 CBY34141.1 - 7.2e-10 39.0 0.1 1.3e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY34141.1 - 6.2e-06 25.7 0.2 1.4e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBY34141.1 - 1.6e-05 24.7 0.3 2.5e-05 24.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBY34141.1 - 7.4e-05 21.6 0.2 7.4e-05 21.6 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 CBY34141.1 - 7.9e-05 21.9 0.2 0.00012 21.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CBY34141.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CBY34141.1 - 0.0011 19.5 2.5 0.0024 18.4 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY34141.1 - 0.0022 17.1 0.3 0.0048 16.0 0.3 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBY34141.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CBY34141.1 - 0.025 13.8 0.2 0.048 12.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CBY34141.1 - 0.045 13.0 0.0 0.045 13.0 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CBY34141.1 - 0.08 12.3 0.3 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sulfatase PF00884.23 CBY34142.1 - 8.2e-19 68.1 0.0 1.1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CBY34142.1 - 1.3e-06 28.6 0.2 3.9e-06 27.0 0.0 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 CBY34142.1 - 0.0013 18.4 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY34142.1 - 0.0036 17.2 0.1 3.2 7.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function DUF229 PF02995.17 CBY34142.1 - 0.018 13.7 0.0 0.028 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF229) Sulfotransfer_1 PF00685.27 CBY34143.1 - 6.8e-05 22.5 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain UCH PF00443.29 CBY34144.1 - 1.3e-47 162.5 1.1 1.3e-47 162.5 1.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY34144.1 - 3e-11 43.5 9.3 3e-11 43.5 9.3 4.2 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2154 PF09922.9 CBY34144.1 - 0.034 14.0 0.0 0.95 9.4 0.0 2.5 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF Apt1 PF10351.9 CBY34144.1 - 2.2 7.1 22.8 4.4 6.1 17.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain IFT57 PF10498.9 CBY34145.1 - 0.00053 19.1 10.5 0.00053 19.1 10.5 2.5 2 1 0 2 2 2 2 Intra-flagellar transport protein 57 Syntaxin_2 PF14523.6 CBY34145.1 - 0.0049 17.2 1.1 0.0049 17.2 1.1 4.2 1 1 3 4 4 4 1 Syntaxin-like protein FlaC_arch PF05377.11 CBY34145.1 - 0.033 14.6 1.8 0.033 14.6 1.8 5.4 5 3 1 6 6 5 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 CBY34145.1 - 0.035 12.7 1.7 0.52 8.8 0.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4995 PF16386.5 CBY34145.1 - 0.059 13.4 0.7 0.35 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF1664 PF07889.12 CBY34145.1 - 0.088 12.8 30.1 0.037 14.1 2.8 4.5 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) CLZ PF16526.5 CBY34145.1 - 0.09 13.1 20.7 0.35 11.3 1.2 5.5 4 4 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 CBY34145.1 - 0.18 11.1 31.2 2 7.7 2.6 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 CBY34145.1 - 0.33 9.1 30.9 0.56 8.3 16.7 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA SlyX PF04102.12 CBY34145.1 - 0.48 11.1 25.0 1.1 9.9 3.7 5.6 3 2 3 6 6 6 0 SlyX Vps51 PF08700.11 CBY34145.1 - 0.7 10.0 22.5 2.5 8.2 1.7 5.5 4 2 2 6 6 6 0 Vps51/Vps67 Snapin_Pallidin PF14712.6 CBY34145.1 - 0.86 10.1 24.0 0.17 12.3 7.3 4.1 3 1 2 5 5 5 0 Snapin/Pallidin DUF4477 PF14780.6 CBY34145.1 - 1.3 8.6 7.5 5.4 6.6 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4477) NPV_P10 PF05531.12 CBY34145.1 - 1.4 9.5 31.0 0.81 10.2 0.3 5.7 2 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 CBY34145.1 - 1.7 8.6 5.8 1.1 9.2 0.2 3.1 2 2 1 3 3 3 0 Apolipoprotein O TSC22 PF01166.18 CBY34145.1 - 1.7 9.0 11.8 9.1 6.7 0.9 3.9 2 2 0 2 2 2 0 TSC-22/dip/bun family Metal_resist PF13801.6 CBY34145.1 - 1.8 8.8 4.7 0.77 10.0 0.2 2.7 3 0 0 3 3 3 0 Heavy-metal resistance DUF16 PF01519.16 CBY34145.1 - 2 8.9 32.2 1.7 9.1 4.5 4.8 1 1 2 3 3 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 CBY34145.1 - 3 7.9 36.8 0.21 11.6 3.6 4.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CBY34145.1 - 3.5 7.8 28.0 0.89 9.7 3.1 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family PSII_Pbs27 PF13326.6 CBY34145.1 - 3.5 7.9 12.5 3.5 8.0 2.3 2.9 2 1 1 3 3 3 0 Photosystem II Pbs27 DUF4349 PF14257.6 CBY34145.1 - 3.6 7.0 20.9 0.014 14.8 5.8 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 CBY34145.1 - 6.7 6.0 28.8 2.3 7.5 13.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CBY34145.1 - 7.3 7.0 29.9 3.9 7.9 11.2 3.1 1 1 1 2 2 2 0 Fez1 CorA PF01544.18 CBY34145.1 - 8.4 5.6 16.0 6.1 6.1 6.0 2.7 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2524 PF10732.9 CBY34145.1 - 8.7 6.7 10.8 0.71 10.2 0.2 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2524) DSPc PF00782.20 CBY34146.1 - 8.6e-20 70.9 0.1 5.2e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY34146.1 - 0.00016 21.9 0.0 0.00028 21.0 0.0 1.4 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY34146.1 - 0.0024 17.5 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 CBY34146.1 - 0.092 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF915 PF06028.11 CBY34146.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CDKN3 PF05706.12 CBY34146.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Cyclin_N PF00134.23 CBY34147.1 - 3.1e-19 69.0 0.4 5.3e-19 68.2 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NPH3 PF03000.14 CBY34147.1 - 0.002 17.8 0.6 0.0034 17.1 0.6 1.4 1 0 0 1 1 1 1 NPH3 family zf-C2H2 PF00096.26 CBY34148.1 - 1.7e-13 50.2 34.2 0.0041 17.5 2.5 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type JmjC PF02373.22 CBY34148.1 - 2.3e-13 50.6 0.0 2.3e-13 50.6 0.0 3.9 5 0 0 5 5 5 1 JmjC domain, hydroxylase zf-H2C2_2 PF13465.6 CBY34148.1 - 9.5e-09 35.3 23.2 8.9e-05 22.7 0.1 5.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY34148.1 - 1.1e-05 25.9 25.2 0.23 12.4 2.6 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf_ZIC PF18366.1 CBY34148.1 - 0.00016 21.7 9.3 0.00027 21.0 1.1 3.9 3 1 1 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 CBY34148.1 - 1.5 9.5 10.6 3.9 8.2 0.6 3.6 2 1 3 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 CBY34148.1 - 1.7 9.0 12.7 4.9 7.5 4.1 3.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CBY34148.1 - 5.5 7.4 18.8 4.3 7.8 0.9 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding FYVE_2 PF02318.16 CBY34149.1 - 0.005 17.0 4.6 0.005 17.0 4.6 2.7 4 0 0 4 4 4 1 FYVE-type zinc finger TackOD1 PF18551.1 CBY34149.1 - 0.021 14.5 13.8 0.31 10.7 10.2 3.2 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CBY34149.1 - 0.42 10.7 13.9 0.3 11.1 2.0 3.2 2 1 1 3 3 3 0 Double zinc ribbon C1_2 PF03107.16 CBY34149.1 - 1.9 8.9 15.3 0.071 13.4 4.0 3.1 3 0 0 3 3 3 0 C1 domain FYVE PF01363.21 CBY34149.1 - 1.9 8.7 15.7 0.39 10.9 10.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger zf-C5HC2 PF02928.16 CBY34149.1 - 2 8.9 14.4 1.2 9.6 11.6 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger CDO_I PF05995.12 CBY34150.1 - 6.3e-39 133.0 0.0 7.4e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CBY34150.1 - 1e-05 25.1 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO DUF485 PF04341.12 CBY34153.1 - 0.019 14.9 0.3 0.023 14.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Sugar_tr PF00083.24 CBY34155.1 - 1.4e-18 67.1 17.4 8.9e-18 64.4 17.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY34155.1 - 1.3e-12 47.4 28.1 4.1e-11 42.4 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBY34155.1 - 0.00011 21.0 0.5 0.00011 21.0 0.5 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Zona_pellucida PF00100.23 CBY34157.1 - 1.2e-42 146.5 5.9 1.5e-42 146.2 5.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4389 PF14333.6 CBY34157.1 - 0.17 11.9 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DAG1 PF05454.11 CBY34157.1 - 0.37 10.1 1.6 3.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2909 PF11137.8 CBY34157.1 - 1 9.3 4.7 0.44 10.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF745 PF05335.13 CBY34159.1 - 0.0038 17.0 5.9 0.0038 17.0 5.9 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF745) ADIP PF11559.8 CBY34159.1 - 0.012 15.7 5.3 0.012 15.7 5.3 3.6 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 CBY34159.1 - 0.03 14.7 15.6 0.49 10.7 1.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GCR1_C PF12550.8 CBY34159.1 - 0.031 14.6 1.8 0.031 14.6 1.8 2.4 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Noelin-1 PF12308.8 CBY34159.1 - 0.16 12.0 2.5 0.93 9.5 2.4 2.4 1 1 0 1 1 1 0 Neurogenesis glycoprotein CALCOCO1 PF07888.11 CBY34159.1 - 0.22 10.4 25.5 0.3 9.9 25.5 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Holin_BhlA PF10960.8 CBY34159.1 - 0.7 9.9 6.0 0.34 10.9 2.0 2.6 2 0 0 2 2 2 0 BhlA holin family CorA PF01544.18 CBY34159.1 - 2.1 7.6 14.5 7.8 5.7 14.4 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF641 PF04859.12 CBY34159.1 - 5.2 7.4 17.0 4.6 7.6 2.5 2.8 2 2 0 2 2 2 0 Plant protein of unknown function (DUF641) G-gamma PF00631.22 CBY34159.1 - 8.2 6.5 9.3 11 6.1 0.8 3.8 3 1 1 4 4 4 0 GGL domain BTG PF07742.12 CBY34160.1 - 2e-36 124.3 0.0 4.2e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 BTG family BTB PF00651.31 CBY34161.1 - 2.1e-25 89.1 0.1 2.8e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain BAF PF02961.14 CBY34162.1 - 1.7e-20 73.2 0.2 2.9e-20 72.5 0.2 1.3 1 0 0 1 1 1 1 Barrier to autointegration factor Tub PF01167.18 CBY34163.1 - 1.2e-89 300.2 0.1 1.6e-89 299.8 0.1 1.2 1 0 0 1 1 1 1 Tub family PAT1 PF09770.9 CBY34163.1 - 0.019 13.3 2.5 0.031 12.6 2.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3527 PF12043.8 CBY34163.1 - 0.021 14.4 0.1 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) COesterase PF00135.28 CBY34164.1 - 1.8e-74 251.5 0.2 3.1e-74 250.7 0.2 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY34164.1 - 4.7e-10 39.7 0.8 0.00033 20.6 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY34164.1 - 0.039 13.4 1.0 0.2 11.1 1.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Phospholip_A2_1 PF00068.19 CBY34165.1 - 3.1e-14 53.4 10.7 5.7e-14 52.5 10.7 1.4 1 0 0 1 1 1 1 Phospholipase A2 Med12 PF09497.10 CBY34166.1 - 0.086 13.1 0.5 43 4.5 0.0 3.7 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 RBP_receptor PF14752.6 CBY34167.1 - 1.5e-51 175.7 26.9 1.9e-31 109.4 15.9 4.0 2 1 1 3 3 3 3 Retinol binding protein receptor Pox_Ag35 PF03286.14 CBY34168.1 - 0.013 15.3 5.9 0.018 14.9 5.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5615 PF18480.1 CBY34168.1 - 0.058 13.2 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ran_BP1 PF00638.18 CBY34169.1 - 3.7e-141 463.1 14.7 7.9e-42 142.4 0.2 4.7 4 0 0 4 4 4 4 RanBP1 domain WH1 PF00568.23 CBY34169.1 - 4.2e-06 26.7 0.2 0.25 11.3 0.0 3.7 3 0 0 3 3 3 2 WH1 domain TPR_1 PF00515.28 CBY34169.1 - 5.6e-06 25.9 9.7 0.00038 20.1 0.5 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY34169.1 - 1.8e-05 24.5 6.6 0.00098 19.1 0.4 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY34169.1 - 8.5e-05 22.5 4.5 0.18 12.1 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY34169.1 - 0.00022 21.5 0.7 0.021 15.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY34169.1 - 0.00037 20.3 0.2 0.4 10.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY34169.1 - 0.00053 20.4 0.7 0.018 15.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY34169.1 - 0.0014 18.8 0.1 0.0071 16.5 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY34169.1 - 0.015 16.0 0.5 0.51 11.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fib_alpha PF08702.10 CBY34169.1 - 0.039 14.2 5.9 0.24 11.6 5.4 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lig_C PF18330.1 CBY34169.1 - 0.062 13.3 0.7 34 4.5 0.0 4.3 4 0 0 4 4 4 0 Ligase Pab1020 C-terminal region TPR_11 PF13414.6 CBY34169.1 - 0.097 12.4 1.8 1.1 9.0 0.0 2.7 2 1 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 CBY34169.1 - 0.14 12.4 0.5 1.9 8.7 0.1 2.9 2 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CBY34169.1 - 0.18 11.9 1.8 11 6.2 0.1 3.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SlyX PF04102.12 CBY34169.1 - 0.42 11.3 3.3 0.86 10.3 0.4 3.1 3 0 0 3 3 2 0 SlyX Ran_BP1 PF00638.18 CBY34170.1 - 1.7e-05 25.1 0.2 0.017 15.4 0.1 2.2 1 1 1 2 2 2 2 RanBP1 domain Peptidase_S8 PF00082.22 CBY34171.1 - 3.5e-49 167.7 2.2 5.4e-49 167.1 2.2 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY34171.1 - 3.9e-20 71.7 0.0 8e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 CBY34171.1 - 6.6e-12 46.0 0.4 1.5e-11 44.9 0.4 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain HgmA PF04209.13 CBY34172.1 - 9e-199 660.5 0.3 1e-198 660.3 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3040 PF11239.8 CBY34174.1 - 0.0065 16.7 0.4 4.3 7.7 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3040) Ion_trans PF00520.31 CBY34175.1 - 8.5e-14 51.4 7.0 7.7e-13 48.2 0.4 2.2 2 0 0 2 2 2 2 Ion transport protein Astacin PF01400.24 CBY34176.1 - 2.5e-57 193.6 1.1 3.8e-57 193.0 1.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MAM PF00629.23 CBY34176.1 - 7.1e-11 42.3 0.1 7.1e-11 42.3 0.1 1.7 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu cEGF PF12662.7 CBY34176.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.3 3 0 0 3 3 3 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY34176.1 - 0.21 11.9 0.2 0.21 11.9 0.2 3.6 2 1 1 3 3 3 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY34176.1 - 2.5 8.5 18.5 4 7.8 0.6 4.3 3 1 1 4 4 4 0 EGF-like domain EGF_3 PF12947.7 CBY34176.1 - 2.6 8.3 17.1 0.12 12.6 0.4 4.2 3 1 1 4 4 4 0 EGF domain Ion_trans PF00520.31 CBY34177.1 - 8.1e-05 22.0 0.2 8.1e-05 22.0 0.2 1.0 1 0 0 1 1 1 1 Ion transport protein Sdh_cyt PF01127.22 CBY34177.1 - 0.014 15.4 0.1 0.014 15.4 0.1 1.0 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TssO PF17561.2 CBY34177.1 - 0.036 14.2 0.2 0.042 13.9 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO PTR2 PF00854.21 CBY34178.1 - 4.8e-94 315.4 13.6 1.5e-82 277.6 2.0 2.9 2 1 1 3 3 3 2 POT family PMP22_Claudin PF00822.20 CBY34178.1 - 0.022 14.6 0.3 0.022 14.6 0.3 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Kelch_1 PF01344.25 CBY34179.1 - 2.6e-45 151.8 9.5 7.4e-10 38.3 0.7 6.1 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY34179.1 - 2.4e-33 113.3 1.8 1.5e-06 28.3 0.0 6.8 5 2 1 6 6 6 6 Kelch motif BTB PF00651.31 CBY34179.1 - 1.5e-28 99.2 0.0 2.5e-27 95.3 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 CBY34179.1 - 1.2e-27 95.6 1.8 3.9e-05 23.8 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.15 CBY34179.1 - 1.6e-23 82.7 0.1 3.7e-23 81.6 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY34179.1 - 9.1e-22 76.2 7.3 0.0061 16.5 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CBY34179.1 - 1.4e-17 63.4 0.1 0.0011 19.0 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY34179.1 - 2.1e-10 40.3 9.7 0.034 14.1 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Peptidase_C47 PF05543.13 CBY34179.1 - 0.00017 21.2 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 Staphopain peptidase C47 EABR PF12180.8 CBY34179.1 - 0.0043 16.6 0.5 0.01 15.4 0.5 1.6 1 0 0 1 1 1 1 TSG101 and ALIX binding domain of CEP55 Glyco_hydro_31 PF01055.26 CBY34181.1 - 3.3e-257 853.7 22.9 7.1e-139 463.8 7.6 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY34181.1 - 5.7e-35 120.0 0.5 1e-20 74.1 0.1 2.5 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 CBY34181.1 - 6.7e-17 61.1 7.6 9.9e-09 34.9 2.6 2.7 2 0 0 2 2 2 2 Trefoil (P-type) domain Gal_mutarotas_2 PF13802.6 CBY34181.1 - 9.2e-08 32.3 5.5 0.00019 21.7 0.8 3.0 2 0 0 2 2 2 2 Galactose mutarotase-like DUF5110 PF17137.4 CBY34181.1 - 0.00021 21.5 0.3 0.51 10.7 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF5110) DUF1533 PF07550.11 CBY34181.1 - 0.02 14.8 0.4 0.86 9.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) WD40_like PF17005.5 CBY34182.1 - 7.8e-05 22.1 0.6 0.0019 17.6 0.1 2.6 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 CBY34182.1 - 8.9e-05 22.7 0.1 1.2 9.5 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY34182.1 - 0.00024 21.8 0.5 0.037 14.9 0.1 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Peptidase_S28 PF05577.12 CBY34184.1 - 1.3e-57 195.5 0.0 1.9e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CBY34184.1 - 1.7e-05 23.7 0.0 2.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 CBY34184.1 - 2.2e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY34184.1 - 3.8e-05 24.4 0.1 0.00064 20.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY34184.1 - 6.8e-05 22.6 0.0 9.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY34184.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 CBY34184.1 - 0.11 11.7 0.3 0.17 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) EGF_CA PF07645.15 CBY34185.1 - 4.5e-24 84.4 52.2 2.2e-09 37.3 7.0 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain hEGF PF12661.7 CBY34185.1 - 1.5e-06 28.6 36.5 0.0085 16.7 4.5 5.3 4 1 0 4 4 4 4 Human growth factor-like EGF cEGF PF12662.7 CBY34185.1 - 5.6e-06 26.2 0.6 5.6e-06 26.2 0.6 5.5 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 CBY34185.1 - 0.00067 19.9 5.9 0.00067 19.9 5.9 4.8 4 0 0 4 4 4 3 EGF-like domain EGF_3 PF12947.7 CBY34185.1 - 0.00085 19.5 60.0 0.022 14.9 7.7 5.4 7 0 0 7 7 7 4 EGF domain FXa_inhibition PF14670.6 CBY34185.1 - 0.0019 18.4 49.6 0.16 12.3 3.9 4.6 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site Lipocalin_2 PF08212.12 CBY34186.1 - 1.3e-14 54.3 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY34186.1 - 0.00027 21.2 0.0 0.00035 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Triabin PF03973.13 CBY34186.1 - 0.15 11.9 0.1 0.52 10.2 0.1 1.9 1 1 0 1 1 1 0 Triabin RPAP1_N PF08621.10 CBY34187.1 - 0.019 14.7 2.1 0.054 13.3 2.1 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF1104 PF06518.11 CBY34187.1 - 0.024 15.0 8.4 0.038 14.4 8.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) Aminopep PF10023.9 CBY34187.1 - 0.033 13.6 0.3 0.035 13.5 0.3 1.2 1 0 0 1 1 1 0 Putative aminopeptidase HSBP1 PF06825.12 CBY34187.1 - 0.033 14.0 4.0 0.4 10.6 3.9 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 SRP_SPB PF02978.19 CBY34187.1 - 0.034 14.8 4.9 0.12 13.0 4.9 1.8 1 1 0 1 1 1 0 Signal peptide binding domain PhageMin_Tail PF10145.9 CBY34187.1 - 0.035 13.9 5.6 0.5 10.2 5.6 2.1 1 1 0 1 1 1 0 Phage-related minor tail protein Rho_Binding PF08912.11 CBY34187.1 - 0.089 13.6 5.0 0.11 13.3 4.6 1.4 1 1 0 1 1 1 0 Rho Binding NPV_P10 PF05531.12 CBY34188.1 - 0.025 15.0 3.5 3.9 8.0 0.0 3.8 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bindin PF02084.15 CBY34188.1 - 0.38 11.0 4.7 0.13 12.5 1.4 1.9 1 1 1 2 2 2 0 Bindin ComX PF05952.12 CBY34188.1 - 0.61 10.1 6.2 36 4.4 0.0 3.8 3 1 1 4 4 4 0 Bacillus competence pheromone ComX COX4 PF02936.14 CBY34188.1 - 1.5 8.9 14.6 0.13 12.3 5.7 3.2 2 1 1 3 3 3 0 Cytochrome c oxidase subunit IV Cas_DxTHG PF09455.10 CBY34188.1 - 1.6 8.2 17.2 2 7.9 17.2 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF1690 PF07956.11 CBY34188.1 - 5.1 7.5 32.2 0.25 11.7 14.3 2.8 1 1 2 3 3 3 0 Protein of Unknown function (DUF1690) RPAP1_N PF08621.10 CBY34188.1 - 7.4 6.4 23.9 0.15 11.9 3.0 3.8 4 1 0 4 4 4 0 RPAP1-like, N-terminal UEV PF05743.13 CBY34189.1 - 9.9e-18 64.2 0.0 2.2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 UEV domain MMR_HSR1 PF01926.23 CBY34189.1 - 1.4e-13 50.9 0.0 4.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.6 CBY34189.1 - 6.3e-07 29.1 8.8 1.2e-06 28.2 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RsgA_GTPase PF03193.16 CBY34189.1 - 1.4e-05 25.1 0.0 0.0029 17.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CBY34189.1 - 2.1e-05 24.1 0.0 4.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Prok-RING_4 PF14447.6 CBY34189.1 - 2.5e-05 24.0 8.8 5.4e-05 23.0 8.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY34189.1 - 3.5e-05 23.7 11.0 6.6e-05 22.8 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain AIG1 PF04548.16 CBY34189.1 - 5.7e-05 22.5 0.1 0.00019 20.8 0.1 1.9 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CBY34189.1 - 0.00011 21.9 0.1 1.3 8.6 0.1 3.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain zf-RING_2 PF13639.6 CBY34189.1 - 0.00025 21.3 9.5 0.00053 20.3 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain Dynamin_N PF00350.23 CBY34189.1 - 0.0044 17.1 0.2 0.0044 17.1 0.2 3.3 3 1 1 4 4 4 1 Dynamin family UQ_con PF00179.26 CBY34189.1 - 0.0093 15.6 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme zf-RING_UBOX PF13445.6 CBY34189.1 - 0.023 14.7 1.8 0.023 14.7 1.8 2.5 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY34189.1 - 0.029 14.2 9.7 0.059 13.2 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAA_15 PF13175.6 CBY34189.1 - 0.043 13.5 0.0 0.043 13.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CBY34189.1 - 0.073 13.3 0.1 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CBY34189.1 - 0.15 12.6 0.1 0.71 10.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter zf-C3HC4 PF00097.25 CBY34189.1 - 0.44 10.5 10.3 1.1 9.2 10.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY34189.1 - 0.5 10.2 8.3 1.1 9.1 8.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZF PF07528.14 CBY34191.1 - 3.7e-50 170.9 0.0 5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DZF domain Gly-rich_Ago1 PF12764.7 CBY34191.1 - 0.99 10.2 6.4 2.5 8.9 6.4 1.7 1 0 0 1 1 1 0 Glycine-rich region of argonaut RRS1 PF04939.12 CBY34192.1 - 3.9e-45 153.6 10.3 3.9e-45 153.6 10.3 2.3 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) YscJ_FliF PF01514.17 CBY34192.1 - 0.24 11.0 5.7 3.7 7.2 0.2 2.6 3 0 0 3 3 3 0 Secretory protein of YscJ/FliF family AHSA1 PF08327.11 CBY34193.1 - 2.5e-19 69.7 1.1 3.9e-19 69.1 1.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein LolB PF03550.14 CBY34194.1 - 0.22 11.6 1.4 3.6 7.6 0.2 2.1 1 1 1 2 2 2 0 Outer membrane lipoprotein LolB APH PF01636.23 CBY34195.1 - 3.5e-43 148.2 0.0 6.5e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 CBY34195.1 - 4.4e-31 108.1 2.7 8.2e-31 107.2 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY34195.1 - 4.7e-18 65.2 0.0 9.9e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HAD_2 PF13419.6 CBY34195.1 - 9.1e-18 65.0 1.1 1.9e-17 63.9 0.5 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acyl-CoA_dh_N PF02771.16 CBY34195.1 - 2e-14 54.2 0.1 1.1e-13 51.8 0.0 2.4 2 0 0 2 2 1 1 Acyl-CoA dehydrogenase, N-terminal domain Hydrolase PF00702.26 CBY34195.1 - 7.8e-09 36.1 0.2 1.9e-07 31.6 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyl-CoA_dh_2 PF08028.11 CBY34195.1 - 6.1e-08 33.0 0.5 1e-07 32.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Hydrolase_like PF13242.6 CBY34195.1 - 3.6e-05 23.7 0.0 8.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Choline_kinase PF01633.20 CBY34195.1 - 0.00044 19.9 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY34195.1 - 0.001 18.5 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase_6 PF13344.6 CBY34195.1 - 0.016 15.3 0.1 0.089 12.9 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 CBY34195.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Acid Phosphatase RIO1 PF01163.22 CBY34195.1 - 0.15 11.6 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 RIO1 family DUF2052 PF09747.9 CBY34196.1 - 0.0079 16.3 5.1 0.0083 16.3 5.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) TetR_C_29 PF17938.1 CBY34196.1 - 0.057 13.5 0.5 0.087 12.9 0.5 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BSP_II PF05432.11 CBY34196.1 - 0.066 12.9 11.5 0.072 12.8 11.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) T2SSM PF04612.12 CBY34196.1 - 0.1 12.7 0.7 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4200 PF13863.6 CBY34196.1 - 0.18 12.2 10.9 0.28 11.6 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Drc1-Sld2 PF11719.8 CBY34196.1 - 0.3 10.6 6.6 0.33 10.5 6.6 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein DNA_pol_phi PF04931.13 CBY34196.1 - 0.89 7.6 11.6 1.1 7.2 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF1676 PF07898.13 CBY34196.1 - 3.3 7.7 5.9 5.7 6.9 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Peptidase_M50 PF02163.22 CBY34197.1 - 7.1e-13 48.4 0.1 1.6e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 CBY34197.1 - 0.0012 18.6 1.8 0.0012 18.6 1.8 1.9 2 0 0 2 2 2 1 Peptidase M50B-like PDZ PF00595.24 CBY34197.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Gal-3-0_sulfotr PF06990.11 CBY34198.1 - 2.8e-11 43.0 0.0 3.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Prefoldin_3 PF13758.6 CBY34198.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF2695 PF10905.8 CBY34198.1 - 0.085 13.1 0.2 0.23 11.7 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2695) DUF1706 PF08020.11 CBY34199.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) SpecificRecomb PF10136.9 CBY34200.1 - 0.11 10.8 0.8 0.25 9.6 0.8 1.7 1 0 0 1 1 1 0 Site-specific recombinase Zincin_2 PF10103.9 CBY34200.1 - 0.13 11.5 2.7 0.1 11.8 0.3 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase SL4P PF17618.2 CBY34200.1 - 0.18 11.9 5.8 0.087 12.9 0.4 3.1 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein PP-binding_2 PF14573.6 CBY34200.1 - 0.65 10.3 3.3 8.6 6.7 0.1 3.7 3 0 0 3 3 3 0 Acyl-carrier 2OG-FeII_Oxy PF03171.20 CBY34201.1 - 8.6e-24 83.9 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY34201.1 - 1.2e-10 42.2 0.0 1.9e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cue1_U7BR PF18499.1 CBY34201.1 - 0.17 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 C2 PF00168.30 CBY34202.1 - 4.3e-08 33.4 0.0 1.3e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 C2 domain ABC_tran PF00005.27 CBY34204.1 - 3.5e-51 173.3 0.2 1.8e-24 86.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBY34204.1 - 1.5e-20 74.2 4.4 8.7e-08 32.3 0.0 4.7 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CBY34204.1 - 8.2e-19 67.9 29.9 6.7e-11 41.9 10.4 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CBY34204.1 - 1e-10 41.8 1.0 6.6e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBY34204.1 - 3.2e-08 33.2 0.3 0.0029 17.3 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY34204.1 - 4.4e-08 33.2 5.1 0.014 15.1 3.4 4.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CBY34204.1 - 5.6e-08 33.5 13.5 0.0013 19.2 0.1 3.5 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.19 CBY34204.1 - 1.4e-07 31.2 1.6 0.7 9.3 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY34204.1 - 9.8e-06 26.1 0.3 0.16 12.4 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBY34204.1 - 0.00039 20.7 0.2 1.7 8.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 CBY34204.1 - 0.0012 18.8 0.5 0.58 10.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 CBY34204.1 - 0.0024 17.8 0.3 0.53 10.3 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CBY34204.1 - 0.0068 16.5 3.8 0.45 10.6 0.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CBY34204.1 - 0.012 15.3 0.0 6.3 6.5 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_27 PF13514.6 CBY34204.1 - 0.014 15.0 0.2 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBY34204.1 - 0.029 13.7 0.1 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CBY34204.1 - 0.03 14.5 0.8 5.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CBY34204.1 - 0.035 13.8 0.1 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBY34204.1 - 0.039 14.3 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 CBY34204.1 - 0.062 13.9 0.2 1.8 9.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CBY34204.1 - 0.066 11.9 2.6 1.6 7.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain MukB PF04310.12 CBY34204.1 - 0.068 13.0 0.1 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 CBY34204.1 - 0.087 12.4 3.3 2.9 7.4 0.6 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 CBY34204.1 - 0.11 11.2 0.1 5.6 5.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 CBY34204.1 - 0.12 12.1 0.5 5.2 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBY34204.1 - 0.12 11.9 2.4 5.6 6.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 CBY34204.1 - 0.18 11.4 0.9 7.5 6.1 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FeoB_N PF02421.18 CBY34204.1 - 0.21 11.1 1.1 10 5.6 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 CBY34204.1 - 0.23 11.7 1.9 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY34204.1 - 0.24 11.4 1.0 11 6.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 CBY34204.1 - 0.66 10.0 2.3 3.4 7.7 0.2 3.0 3 0 0 3 3 3 0 Dynamin family Sde2_N_Ubi PF13019.6 CBY34206.1 - 5.4e-19 68.6 1.4 5.4e-19 68.6 1.4 2.4 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 CBY34206.1 - 7.4e-19 67.2 0.3 2.2e-18 65.7 0.1 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal Miga PF10265.9 CBY34208.1 - 3.2e-60 204.6 5.8 2.1e-59 201.9 5.8 1.9 1 1 0 1 1 1 1 Mitoguardin Lipocalin_7 PF14651.6 CBY34210.1 - 1.3e-13 51.0 0.4 1.4e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1521 PF07481.11 CBY34210.1 - 0.029 14.4 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) EGF_3 PF12947.7 CBY34211.1 - 4.8e-44 148.2 353.0 4.6e-08 33.1 8.1 22.9 20 2 1 22 22 22 14 EGF domain EGF_CA PF07645.15 CBY34211.1 - 1.7e-20 72.9 89.2 6.3e-09 35.9 9.1 22.1 17 3 5 22 22 22 8 Calcium-binding EGF domain EGF PF00008.27 CBY34211.1 - 5.2e-11 42.6 326.7 3.8e-06 27.1 7.6 23.5 21 2 0 22 22 22 12 EGF-like domain hEGF PF12661.7 CBY34211.1 - 7.8e-05 23.2 15.6 0.00046 20.7 3.7 25.8 23 1 0 23 23 23 11 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY34211.1 - 0.00044 20.2 11.6 0.00044 20.2 11.6 21.5 21 0 0 21 21 21 11 MSP1 EGF domain 1 cEGF PF12662.7 CBY34211.1 - 0.011 15.6 203.9 0.051 13.5 5.5 22.9 20 4 2 22 22 22 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY34211.1 - 0.012 15.9 1.5 0.012 15.9 1.5 22.3 22 1 0 22 22 22 0 Pvs28 EGF domain DUF3288 PF11691.8 CBY34211.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) Zona_pellucida PF00100.23 CBY34212.1 - 1.2e-07 31.8 1.5 2e-07 31.1 1.5 1.4 1 1 0 1 1 1 1 Zona pellucida-like domain Ig_3 PF13927.6 CBY34213.1 - 2.3e-15 57.0 1.3 1.7e-11 44.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY34213.1 - 1.4e-12 47.8 0.2 7.5e-07 29.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY34213.1 - 2e-09 37.4 0.4 2.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 CBY34213.1 - 2.6e-09 37.1 0.1 4.7e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY34213.1 - 4.5e-05 23.2 0.2 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 V-set PF07686.17 CBY34213.1 - 0.00017 21.7 0.9 0.032 14.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.11 CBY34213.1 - 0.0084 16.2 0.8 0.013 15.6 0.1 1.6 2 0 0 2 2 2 1 Podoplanin C2-set_2 PF08205.12 CBY34213.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY34213.1 - 0.092 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain PMP1_2 PF08114.11 CBY34213.1 - 1.1 9.1 3.7 0.35 10.7 0.7 1.7 2 0 0 2 2 2 0 ATPase proteolipid family Arm PF00514.23 CBY34214.1 - 0.0068 16.4 1.4 30 4.8 0.0 5.2 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3541 PF12060.8 CBY34214.1 - 0.018 14.8 0.2 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) LRR_9 PF14580.6 CBY34214.1 - 0.047 13.2 1.4 0.082 12.4 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat MapZ_EC1 PF18041.1 CBY34215.1 - 0.03 14.6 0.8 0.065 13.5 0.8 1.6 1 0 0 1 1 1 0 MapZ extracellular domain 1 DUF4434 PF14488.6 CBY34215.1 - 0.066 13.2 0.5 0.15 12.0 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Kri1 PF05178.12 CBY34215.1 - 0.39 11.3 5.5 0.15 12.6 2.3 2.0 1 1 1 2 2 2 0 KRI1-like family RsdA_SigD_bd PF16751.5 CBY34216.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region SH3_9 PF14604.6 CBY34217.1 - 2.2e-12 46.6 0.1 8.5e-11 41.5 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY34217.1 - 2.4e-09 36.6 0.3 1.2e-08 34.4 0.0 2.3 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.17 CBY34217.1 - 2.4e-08 33.5 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain hSH3 PF14603.6 CBY34217.1 - 5.6e-05 23.5 0.0 0.019 15.4 0.0 2.4 2 0 0 2 2 2 2 Helically-extended SH3 domain DUF559 PF04480.12 CBY34217.1 - 0.0058 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) SH3_3 PF08239.11 CBY34217.1 - 0.018 15.3 0.6 0.062 13.6 0.2 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain BAR PF03114.18 CBY34217.1 - 0.14 11.8 2.2 0.64 9.6 0.6 2.2 1 1 1 2 2 2 0 BAR domain RhoGEF PF00621.20 CBY34218.1 - 2e-27 96.6 0.1 4.7e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF4164 PF13747.6 CBY34218.1 - 0.083 13.2 3.6 0.28 11.5 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Lzipper-MIP1 PF14389.6 CBY34218.1 - 4.7 7.6 7.3 2.1 8.7 2.3 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MMR_HSR1_Xtn PF16897.5 CBY34219.1 - 3e-41 139.7 1.1 5.2e-41 138.9 1.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBY34219.1 - 2.3e-19 69.2 0.1 4.3e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBY34219.1 - 7.5e-19 67.9 0.0 2.2e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY34219.1 - 3.5e-10 39.6 0.2 2.1e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBY34219.1 - 0.0024 16.9 0.4 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 CBY34219.1 - 0.003 17.1 0.1 1.7 8.2 0.0 3.6 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBY34219.1 - 0.041 13.9 0.4 3.5 7.6 0.2 2.5 1 1 1 2 2 2 0 Dynamin family RhoGEF PF00621.20 CBY34220.1 - 1.4e-29 103.6 0.3 3.3e-29 102.4 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain BRCT PF00533.26 CBY34220.1 - 1.9e-09 37.8 0.0 0.0044 17.4 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBY34220.1 - 0.0023 18.2 0.0 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CBY34220.1 - 0.0037 17.2 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain MFS_1 PF07690.16 CBY34221.1 - 3.5e-25 88.7 17.4 3.5e-25 88.7 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY34221.1 - 0.00031 19.7 15.3 0.006 15.5 1.7 2.5 2 1 0 2 2 2 2 MFS_1 like family GWT1 PF06423.12 CBY34221.1 - 0.74 9.9 6.9 42 4.2 0.0 3.6 2 1 0 2 2 2 0 GWT1 DUF2859 PF11072.8 CBY34223.1 - 1.4 8.6 4.8 18 5.1 0.1 3.6 2 1 3 5 5 5 0 Protein of unknown function (DUF2859) Glyco_hydro_20 PF00728.22 CBY34224.1 - 4.8e-07 29.5 0.0 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain FlaC_arch PF05377.11 CBY34224.1 - 0.04 14.3 0.9 2.9 8.4 1.5 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) EF-G-binding_N PF07299.11 CBY34224.1 - 2 9.0 7.6 7.8 7.1 3.6 3.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal RIC1 PF07064.13 CBY34225.1 - 1.4e-83 280.2 0.3 2.9e-83 279.1 0.3 1.5 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CBY34225.1 - 0.075 13.3 0.0 1.5 9.2 0.0 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DED PF01335.21 CBY34225.1 - 0.8 10.1 5.7 0.2 12.0 1.5 2.2 2 0 0 2 2 2 0 Death effector domain Pkinase PF00069.25 CBY34226.1 - 1.1e-08 34.8 0.1 0.00089 18.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34226.1 - 7.6e-06 25.4 1.9 0.0037 16.6 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase DUF5121 PF17165.4 CBY34227.1 - 0.031 14.7 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) Pkinase PF00069.25 CBY34228.1 - 1.1e-08 34.8 0.1 0.00089 18.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34228.1 - 7.6e-06 25.4 1.9 0.0037 16.6 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase YfzA PF14118.6 CBY34229.1 - 0.052 13.9 0.2 0.091 13.2 0.2 1.4 1 0 0 1 1 1 0 YfzA-like protein DnaT PF17948.1 CBY34229.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 DnaT DNA-binding domain DTW PF03942.15 CBY34231.1 - 9.5e-28 97.3 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 DTW domain RE_EcoO109I PF14511.6 CBY34231.1 - 0.096 12.3 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I RRM_1 PF00076.22 CBY34232.1 - 2e-19 69.2 0.0 2.9e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY34232.1 - 0.0091 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.9 CBY34232.1 - 0.027 14.0 4.4 0.072 12.6 0.0 2.3 2 1 0 2 2 2 0 RNA-recognition motif muHD PF10291.9 CBY34233.1 - 1.3e-06 28.1 0.1 3.2e-06 26.8 0.1 1.6 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CBY34233.1 - 1.8e-05 24.9 0.1 6.1e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DegS PF05384.11 CBY34233.1 - 0.025 14.1 5.3 0.069 12.6 0.4 2.6 1 1 0 2 2 2 0 Sensor protein DegS Palm_thioest PF02089.15 CBY34234.1 - 2.8e-77 259.8 0.1 3.1e-77 259.7 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CBY34234.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Nif11 PF07862.11 CBY34234.1 - 0.66 10.3 2.2 5.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Nif11 domain FAD_binding_7 PF03441.14 CBY34235.1 - 1.3e-62 210.9 0.7 1.9e-62 210.4 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBY34235.1 - 2.1e-27 96.1 0.0 8.2e-27 94.2 0.0 1.9 1 1 1 2 2 2 1 DNA photolyase EMP24_GP25L PF01105.24 CBY34236.1 - 2.3e-38 132.0 0.2 2.6e-38 131.8 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UDPG_MGDP_dh_N PF03721.14 CBY34236.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BPL_LplA_LipB PF03099.19 CBY34237.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HEAT_2 PF13646.6 CBY34238.1 - 0.00028 21.2 1.0 0.09 13.2 0.1 3.8 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 CBY34238.1 - 0.002 18.2 7.0 3.3 8.2 0.1 4.9 5 0 0 5 5 5 2 HEAT repeat RTTN_N PF14726.6 CBY34238.1 - 0.0045 17.8 5.2 0.89 10.4 0.4 4.2 4 1 0 4 4 4 2 Rotatin, an armadillo repeat protein, centriole functioning 7TMR-HDED PF07697.11 CBY34238.1 - 0.015 15.5 0.4 1.4 9.0 0.0 2.9 2 1 0 2 2 2 0 7TM-HD extracellular CtsR_C PF17727.1 CBY34238.1 - 0.19 11.9 2.3 0.29 11.3 0.2 2.5 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Sec7_N PF12783.7 CBY34238.1 - 3.2 7.6 14.6 0.27 11.1 0.1 4.7 3 2 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Transmemb_17 PF09799.9 CBY34239.1 - 1.1e-16 61.4 10.9 1.4e-16 61.0 10.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein Transmemb_17 PF09799.9 CBY34240.1 - 5.9e-24 84.7 7.1 6.8e-24 84.5 7.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein Babuvirus_MP PF07234.11 CBY34240.1 - 0.41 10.8 7.9 0.56 10.4 0.4 2.1 2 0 0 2 2 2 0 Movement and RNA silencing protein M20_dimer PF07687.14 CBY34242.1 - 0.063 13.2 0.1 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain DUF3439 PF11921.8 CBY34243.1 - 5.9 6.9 21.6 13 5.7 21.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CBY34243.1 - 6.2 4.9 22.3 12 3.9 22.3 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyoxalase_4 PF13669.6 CBY34244.1 - 7.8e-06 26.1 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CBY34244.1 - 0.02 15.1 0.1 0.054 13.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TSP_1 PF00090.19 CBY34245.1 - 1.5e-23 82.7 83.6 4.2e-08 33.3 9.2 5.7 6 1 1 7 7 7 4 Thrombospondin type 1 domain INTAP PF16617.5 CBY34245.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.2 3 1 1 4 4 4 0 Intersectin and clathrin adaptor AP2 binding region Sulfotransfer_4 PF17784.1 CBY34246.1 - 1.5e-45 155.7 0.1 2e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY34246.1 - 0.0052 17.2 0.0 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family Asp PF00026.23 CBY34247.1 - 3.8e-19 69.2 0.1 4.7e-19 69.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CBY34247.1 - 0.0023 18.2 0.0 0.003 17.8 0.0 1.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 CBY34248.1 - 1.6e-32 113.2 0.0 1.9e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease O-FucT PF10250.9 CBY34249.1 - 5.2e-06 26.4 1.2 4.1e-05 23.5 1.2 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ephrin_rec_like PF07699.13 CBY34250.1 - 4.4e-06 26.4 29.4 0.00023 20.9 6.2 56.5 36 15 19 60 60 60 37 Putative ephrin-receptor like DUF2853 PF11015.8 CBY34250.1 - 3.3 8.4 6.7 1.8 9.3 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) Ion_trans_2 PF07885.16 CBY34251.1 - 4e-15 55.5 12.1 2.3e-11 43.5 1.3 2.7 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CBY34251.1 - 1.1e-13 51.0 17.9 3.4e-08 33.0 1.6 3.1 2 1 1 3 3 3 3 Ion transport protein BTB_2 PF02214.22 CBY34251.1 - 3.9e-13 49.6 0.1 8e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain ASFV_360 PF01671.16 CBY34251.1 - 0.0025 17.4 2.7 1.1 8.8 0.2 2.4 1 1 1 2 2 2 2 African swine fever virus multigene family 360 protein HMW1C_N PF18071.1 CBY34251.1 - 0.048 13.4 1.2 9 6.1 0.1 2.5 2 0 0 2 2 2 0 HMW1C N-terminal Mating_N PF12731.7 CBY34251.1 - 0.058 13.5 1.8 5.6 7.1 0.1 2.6 2 1 0 2 2 2 0 Mating-type protein beta 1 SIX1_SD PF16878.5 CBY34253.1 - 2e-30 105.6 0.0 5.3e-30 104.2 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulator, SIX1, N-terminal SD domain Phage_mat-A PF03863.13 CBY34253.1 - 0.062 12.2 0.2 0.099 11.5 0.2 1.3 1 0 0 1 1 1 0 Phage maturation protein Nckap1 PF09735.9 CBY34254.1 - 2.7e-87 294.0 1.9 3.2e-87 293.7 1.9 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DUF508 PF04370.12 CBY34254.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Nckap1 PF09735.9 CBY34255.1 - 1.9e-214 715.0 23.8 2.1e-214 714.9 23.8 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Npa1 PF11707.8 CBY34255.1 - 0.024 14.0 0.4 0.024 14.0 0.4 1.8 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal DUF1798 PF08807.10 CBY34255.1 - 0.37 10.9 10.2 2.1 8.5 0.1 4.6 4 1 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) Ank_4 PF13637.6 CBY34256.1 - 1.9e-12 47.4 0.3 0.0018 18.8 0.0 6.3 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY34256.1 - 3.1e-11 43.7 1.4 5.3e-05 23.7 0.0 5.5 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.30 CBY34256.1 - 7.1e-08 32.6 0.9 0.65 10.6 0.0 6.1 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 CBY34256.1 - 1.9e-06 27.8 0.6 11 6.9 0.0 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 CBY34256.1 - 1.6e-05 25.1 1.1 11 6.5 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) TRAPPC-Trs85 PF12739.7 CBY34257.1 - 1.2e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF11 PF01345.18 CBY34257.1 - 0.014 15.7 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 Mpv17_PMP22 PF04117.12 CBY34258.1 - 0.024 14.8 0.3 0.052 13.8 0.3 1.5 1 0 0 1 1 1 0 Mpv17 / PMP22 family RRM_1 PF00076.22 CBY34259.1 - 1.3e-20 72.9 0.0 1.9e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY34259.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY34259.1 - 0.059 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY34259.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 CBY34259.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-gua_Ptrans PF00217.19 CBY34261.1 - 4.3e-59 199.6 0.0 5.6e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY34261.1 - 1.9e-25 89.1 0.0 3.1e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain cNMP_binding PF00027.29 CBY34262.1 - 4.1e-15 55.6 0.0 7.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CBY34262.1 - 4.7e-15 55.5 14.2 8.5e-15 54.6 14.2 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_N PF08412.10 CBY34262.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Ion_trans_2 PF07885.16 CBY34262.1 - 0.065 13.2 5.1 0.15 12.0 4.2 2.1 1 1 1 2 2 2 0 Ion channel Homeodomain PF00046.29 CBY34264.1 - 1.2e-09 37.9 0.9 2.9e-09 36.6 0.3 2.0 2 0 0 2 2 2 1 Homeodomain DUF5605 PF18310.1 CBY34265.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) Astacin PF01400.24 CBY34266.1 - 1.2e-19 70.7 0.0 1.2e-19 70.7 0.0 3.4 2 2 1 3 3 3 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY34266.1 - 0.024 14.9 2.8 0.051 13.8 2.8 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Astro_capsid_p2 PF16580.5 CBY34267.1 - 0.0032 17.0 0.7 0.0043 16.5 0.7 1.2 1 0 0 1 1 1 1 C-terminal tail of astrovirus capsid projection or spike UQ_con PF00179.26 CBY34268.1 - 3.5e-19 68.8 0.1 8.7e-19 67.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme SpoIIIAH PF12685.7 CBY34268.1 - 0.0054 16.6 4.1 0.0073 16.2 4.1 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein NPR3 PF03666.13 CBY34268.1 - 0.03 13.1 1.7 0.039 12.7 1.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2207 PF09972.9 CBY34268.1 - 0.031 13.1 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Presenilin PF01080.17 CBY34268.1 - 0.11 11.2 1.5 0.14 10.9 1.5 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBY34268.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RINGv PF12906.7 CBY34269.1 - 4.9e-12 45.8 11.2 4.9e-12 45.8 11.2 2.1 2 0 0 2 2 2 1 RING-variant domain FANCL_C PF11793.8 CBY34269.1 - 0.017 15.3 7.5 0.033 14.4 7.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CBY34269.1 - 0.066 13.6 11.5 0.045 14.1 9.0 2.0 2 0 0 2 2 2 0 Ring finger domain TMEM208_SND2 PF05620.11 CBY34270.1 - 4e-26 91.8 0.8 7.4e-26 90.9 0.8 1.4 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF4604 PF15377.6 CBY34271.1 - 4e-19 69.7 17.4 5.2e-19 69.3 17.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Penicil_amidase PF01804.18 CBY34272.1 - 0.037 13.0 0.2 0.038 12.9 0.2 1.0 1 0 0 1 1 1 0 Penicillin amidase zf-C2H2 PF00096.26 CBY34272.1 - 0.073 13.6 9.2 0.29 11.7 0.8 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Astacin PF01400.24 CBY34273.1 - 5.9e-36 123.9 4.0 3.6e-26 92.0 0.2 2.2 1 1 0 2 2 2 2 Astacin (Peptidase family M12A) 5_nucleotid_C PF02872.18 CBY34273.1 - 3.3e-29 102.1 0.0 5.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CBY34273.1 - 4.5e-13 50.2 0.1 1.2e-12 48.8 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ldl_recept_a PF00057.18 CBY34273.1 - 0.013 15.7 10.3 0.018 15.3 6.5 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A AAA_35 PF14516.6 CBY34273.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Tcp11 PF05794.13 CBY34274.1 - 1.5e-57 195.7 0.0 1.8e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Trns_repr_metal PF02583.17 CBY34274.1 - 0.04 14.3 0.8 0.18 12.2 0.0 2.6 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor CTP_transf_like PF01467.26 CBY34275.1 - 2.1e-23 83.1 0.0 5.2e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like A_deaminase PF00962.22 CBY34275.1 - 3.5e-12 46.3 0.0 5.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase YEATS PF03366.16 CBY34275.1 - 0.00093 19.1 0.0 0.003 17.5 0.0 1.9 1 0 0 1 1 1 1 YEATS family NTP_transferase PF00483.23 CBY34275.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase DUF4594 PF15266.6 CBY34277.1 - 4.6e-05 23.8 14.8 4.6e-05 23.8 14.8 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) PhoLip_ATPase_C PF16212.5 CBY34278.1 - 2e-81 273.5 28.4 5e-81 272.1 28.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY34278.1 - 1.2e-22 79.3 2.6 3.5e-22 77.9 2.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBY34278.1 - 1.5e-08 34.6 0.0 6.5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY34278.1 - 2.9e-08 34.3 0.1 0.00076 19.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY34278.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY34278.1 - 0.012 15.1 0.0 0.012 15.1 0.0 2.7 3 0 0 3 3 3 0 E1-E2 ATPase DUF3487 PF11990.8 CBY34278.1 - 0.54 10.1 0.0 0.54 10.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3487) DUF3899 PF13038.6 CBY34278.1 - 6.6 7.3 13.3 0.77 10.3 7.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ras PF00071.22 CBY34279.1 - 5.6e-66 221.1 0.3 6.7e-66 220.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY34279.1 - 5.9e-36 123.3 0.2 1.1e-35 122.5 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY34279.1 - 3e-16 59.4 0.3 3.7e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY34279.1 - 1.7e-06 27.6 0.2 2.1e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY34279.1 - 4.8e-06 26.2 0.0 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY34279.1 - 8.1e-05 22.1 0.1 0.0001 21.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY34279.1 - 0.00046 20.2 0.1 0.00069 19.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY34279.1 - 0.0015 18.4 0.4 1 9.3 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 CBY34279.1 - 0.065 12.7 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3963 PF13124.6 CBY34279.1 - 0.12 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) SNARE_assoc PF09335.11 CBY34281.1 - 3.5e-20 72.7 1.3 3.5e-20 72.7 1.3 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein SpoVAC_SpoVAEB PF03862.13 CBY34281.1 - 0.0045 17.3 0.2 0.17 12.2 0.1 2.4 2 0 0 2 2 2 1 SpoVAC/SpoVAEB sporulation membrane protein UPF0016 PF01169.19 CBY34281.1 - 0.037 14.4 1.1 0.78 10.1 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 TFIIF_alpha PF05793.12 CBY34282.1 - 0.18 10.4 22.6 0.21 10.1 22.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 CBY34282.1 - 1.4 7.7 23.7 1.7 7.4 23.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAPS PF04499.15 CBY34282.1 - 2.7 6.7 11.8 3 6.5 11.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 CBY34282.1 - 5.1 5.5 13.5 5.1 5.5 13.5 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 CBY34282.1 - 9.5 4.4 7.7 12 4.1 7.7 1.2 1 0 0 1 1 1 0 Menin Steroid_dh PF02544.16 CBY34283.1 - 2.9e-08 33.8 1.3 5.8e-08 32.9 1.3 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase BAG PF02179.16 CBY34284.1 - 3.1e-10 40.3 5.9 3.1e-10 40.3 5.9 2.4 2 0 0 2 2 2 1 BAG domain Baculo_PEP_C PF04513.12 CBY34284.1 - 0.09 12.8 0.0 13 5.8 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSCB_C PF07743.13 CBY34284.1 - 3.7 8.1 16.4 2.9 8.4 0.7 3.9 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain DUF573 PF04504.14 CBY34284.1 - 3.9 8.2 9.9 0.26 12.0 3.3 2.4 2 2 1 3 3 3 0 Protein of unknown function, DUF573 Alpha_kinase PF02816.18 CBY34285.1 - 0.035 14.2 2.7 0.08 13.1 0.2 2.7 3 0 0 3 3 3 0 Alpha-kinase family TolA_bind_tri PF16331.5 CBY34286.1 - 0.0012 18.9 3.3 0.0028 17.7 3.3 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation TSC22 PF01166.18 CBY34286.1 - 0.0023 18.2 1.0 0.0084 16.4 1.0 2.0 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF641 PF04859.12 CBY34286.1 - 0.0037 17.6 2.5 0.0037 17.6 2.5 2.1 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 CBY34286.1 - 0.0068 15.7 2.7 0.0068 15.7 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Csm1_N PF18504.1 CBY34286.1 - 0.013 15.8 2.7 0.013 15.8 2.7 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain Troponin PF00992.20 CBY34286.1 - 0.018 15.3 5.0 0.018 15.3 5.0 2.4 2 1 0 2 2 2 0 Troponin BRE1 PF08647.11 CBY34286.1 - 0.02 15.0 3.0 0.02 15.0 3.0 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 CBY34286.1 - 0.022 14.6 1.9 0.022 14.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TLE_N PF03920.15 CBY34286.1 - 0.055 13.5 1.4 0.13 12.4 1.4 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF2205 PF10224.9 CBY34286.1 - 0.4 10.7 6.1 0.23 11.4 1.0 2.5 1 1 1 2 2 2 0 Short coiled-coil protein YabA PF06156.13 CBY34286.1 - 0.92 10.2 9.3 0.22 12.2 1.9 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 CBY34286.1 - 1.7 9.2 11.5 0.21 12.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_23 PF13476.6 CBY34286.1 - 1.8 9.0 11.6 2.8 8.4 11.6 1.2 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.11 CBY34286.1 - 2.5 8.2 9.3 0.55 10.3 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 CBY34286.1 - 3.5 6.9 9.7 1.3 8.3 6.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 CBY34286.1 - 4.3 7.2 9.9 0.37 10.7 0.4 2.2 2 0 0 2 2 2 0 Aphid transmission protein DivIC PF04977.15 CBY34286.1 - 6.5 6.6 13.8 0.076 12.8 5.6 2.0 2 1 1 3 3 3 0 Septum formation initiator FAM76 PF16046.5 CBY34286.1 - 8.4 5.7 12.8 15 4.9 12.8 1.4 1 1 0 1 1 1 0 FAM76 protein RNA_pol_Rpb4 PF03874.16 CBY34287.1 - 5e-20 72.1 6.2 5.6e-20 71.9 6.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 RcpC PF16976.5 CBY34287.1 - 0.022 14.8 2.5 0.04 14.0 2.5 1.4 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB DUF4946 PF16304.5 CBY34287.1 - 0.044 13.5 0.4 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4946) DUF4473 PF14747.6 CBY34287.1 - 0.063 13.8 1.7 0.14 12.7 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) Toprim_C_rpt PF13368.6 CBY34287.1 - 0.26 11.3 1.4 0.49 10.4 1.4 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat Peptidase_S24 PF00717.23 CBY34288.1 - 3.7e-06 26.8 0.7 9.4e-06 25.5 0.7 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBY34288.1 - 0.00084 19.1 0.0 0.057 13.2 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF417 PF04224.12 CBY34289.1 - 0.014 15.0 0.4 0.02 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF3671 PF12420.8 CBY34289.1 - 0.058 13.5 2.1 0.091 12.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function SRP-alpha_N PF04086.13 CBY34290.1 - 0.023 14.7 6.6 0.026 14.4 2.5 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4449 PF14613.6 CBY34290.1 - 0.09 12.9 8.6 0.046 13.8 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) DUF3027 PF11228.8 CBY34290.1 - 0.18 11.8 2.9 0.29 11.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) UPAR_LY6 PF00021.21 CBY34290.1 - 0.22 12.2 14.3 0.49 11.1 14.3 1.6 1 1 0 1 1 1 0 u-PAR/Ly-6 domain DUF1700 PF08006.11 CBY34290.1 - 0.23 11.0 2.0 0.33 10.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Fe-ADH PF00465.19 CBY34290.1 - 0.25 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF1764 PF08576.10 CBY34290.1 - 3 8.8 15.2 0.15 13.0 8.9 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RCR PF12273.8 CBY34291.1 - 0.035 14.8 0.9 0.061 14.0 0.9 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Phage_holin_2_1 PF04971.12 CBY34291.1 - 0.067 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S Cadherin PF00028.17 CBY34292.1 - 5.9e-28 97.2 9.3 5.3e-10 39.6 0.5 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_3 PF16184.5 CBY34292.1 - 2.8e-09 37.0 6.9 0.0026 17.7 0.0 4.2 3 1 1 4 4 4 2 Cadherin-like Cadherin_C PF01049.17 CBY34292.1 - 0.00011 22.6 0.4 0.00029 21.2 0.4 1.7 1 0 0 1 1 1 1 Cadherin cytoplasmic region TctB PF07331.11 CBY34292.1 - 0.036 14.3 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Trypsin PF00089.26 CBY34293.1 - 4.7e-44 150.8 3.1 8.4e-44 150.0 3.1 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY34293.1 - 0.00025 22.0 0.5 0.00053 20.9 0.5 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Kelch_3 PF13415.6 CBY34294.1 - 0.039 14.3 0.4 3.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY34294.1 - 0.046 13.3 1.9 0.18 11.4 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Cyt_b-c1_8 PF10890.8 CBY34294.1 - 0.092 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 BNIP2 PF12496.8 CBY34295.1 - 0.015 15.7 0.7 0.018 15.5 0.7 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Forkhead PF00250.18 CBY34296.1 - 2.1e-28 98.4 1.9 6.4e-28 96.9 1.9 1.8 1 0 0 1 1 1 1 Forkhead domain PhoLip_ATPase_C PF16212.5 CBY34297.1 - 3.6e-56 190.7 27.7 3.6e-56 190.7 27.7 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY34297.1 - 1.3e-19 69.6 1.6 4.5e-19 67.9 1.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBY34297.1 - 4.5e-14 53.2 3.3 7.5e-12 46.0 3.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY34297.1 - 1.5e-09 37.8 0.0 3.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBY34297.1 - 5.9e-08 32.4 0.0 5.9e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBY34297.1 - 6.5e-05 22.8 0.1 0.00035 20.4 0.1 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Trypsin PF00089.26 CBY34300.1 - 4.7e-42 144.3 1.0 6.4e-42 143.8 1.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY34300.1 - 4.4e-06 27.7 0.8 1.3e-05 26.2 0.0 2.0 1 1 1 2 2 2 2 Trypsin-like peptidase domain DUF1833 PF08875.11 CBY34300.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) SCAMP PF04144.13 CBY34301.1 - 0.065 13.5 10.9 0.027 14.8 7.1 2.2 2 1 0 2 2 2 0 SCAMP family SUR7 PF06687.12 CBY34301.1 - 6.9 6.2 11.4 4.4 6.9 0.4 2.8 3 0 0 3 3 3 0 SUR7/PalI family Na_sulph_symp PF00939.19 CBY34302.1 - 1.8e-63 215.2 18.6 5.1e-35 121.4 4.0 2.8 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY34302.1 - 3.5e-30 105.2 43.0 2.3e-12 46.8 13.5 3.1 2 1 1 3 3 3 3 Citrate transporter 2TM PF13239.6 CBY34303.1 - 0.038 14.3 1.3 0.071 13.4 1.3 1.4 1 0 0 1 1 1 0 2TM domain DUF3007 PF11460.8 CBY34303.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) FtsX_ECD PF18075.1 CBY34304.1 - 0.069 13.8 1.3 0.14 12.8 1.3 1.5 1 0 0 1 1 1 0 FtsX extracellular domain LMBR1 PF04791.16 CBY34304.1 - 0.37 9.7 1.3 0.37 9.6 1.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CBY34304.1 - 0.51 8.2 7.5 0.67 7.8 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short_C2 PF13561.6 CBY34305.1 - 3.5e-50 170.8 0.1 4.4e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY34305.1 - 9e-48 162.3 0.2 1.1e-47 162.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY34305.1 - 3.5e-14 53.1 0.1 5.4e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CBY34305.1 - 0.00069 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBY34305.1 - 0.0018 18.2 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 CBY34305.1 - 0.039 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 CBY34305.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) LRR_8 PF13855.6 CBY34306.1 - 5.4e-21 74.1 2.6 1.9e-13 50.0 0.3 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY34306.1 - 2.2e-10 40.6 6.9 8.1e-06 26.1 0.8 3.9 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY34306.1 - 2.8e-06 27.3 0.0 5.4e-06 26.4 0.0 1.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY34306.1 - 8.2e-05 22.2 0.7 0.00016 21.3 0.2 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRRNT PF01462.18 CBY34306.1 - 0.0014 18.3 2.2 0.0066 16.1 2.2 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 CBY34306.1 - 0.012 16.0 2.7 7.2 7.6 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 CBY34307.1 - 2.2e-33 113.8 51.9 1.8e-12 46.8 3.7 6.1 2 2 4 6 6 6 6 Leucine rich repeat EGF PF00008.27 CBY34307.1 - 8.8e-22 77.1 130.0 1.5e-07 31.6 5.8 12.2 10 2 0 11 11 10 7 EGF-like domain LRR_4 PF12799.7 CBY34307.1 - 4.6e-19 68.2 41.1 1.8e-06 28.2 1.1 6.8 5 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY34307.1 - 1.4e-12 47.5 15.4 5.4e-06 26.0 1.8 3.8 2 2 2 4 4 4 4 Leucine-rich repeat Laminin_G_1 PF00054.23 CBY34307.1 - 1.5e-12 47.8 0.1 2.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CBY34307.1 - 2.3e-11 44.4 0.0 4.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain LRR_5 PF13306.6 CBY34307.1 - 2e-08 34.2 10.9 1.3e-05 25.2 3.2 3.8 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRRCT PF01463.24 CBY34307.1 - 7.7e-05 22.9 0.3 13 6.6 0.0 4.2 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain hEGF PF12661.7 CBY34307.1 - 0.00042 20.9 5.5 0.00042 20.9 5.5 13.1 13 1 0 13 13 11 6 Human growth factor-like EGF EGF_2 PF07974.13 CBY34307.1 - 0.00051 20.3 9.1 0.00051 20.3 9.1 12.5 13 0 0 13 13 12 7 EGF-like domain LRRNT PF01462.18 CBY34307.1 - 0.0034 17.0 3.2 0.0034 17.0 3.2 6.9 10 0 0 10 10 8 1 Leucine rich repeat N-terminal domain EGF_CA PF07645.15 CBY34307.1 - 0.0092 16.2 10.0 0.0092 16.2 10.0 12.1 8 2 4 12 12 10 2 Calcium-binding EGF domain LRR_6 PF13516.6 CBY34307.1 - 0.027 14.5 8.4 22 5.4 0.3 5.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBY34307.1 - 0.034 14.7 31.1 2.2 9.2 0.2 9.2 10 0 0 10 10 8 0 Leucine Rich Repeat 5HT_transport_N PF03491.13 CBY34307.1 - 0.17 12.1 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Sulfotransfer_1 PF00685.27 CBY34308.1 - 9.9e-09 35.1 0.3 9.3e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY34308.1 - 5.4e-05 23.7 0.0 8.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 CBY34309.1 - 3.7e-30 105.1 12.1 5.6e-30 104.5 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY34309.1 - 0.033 13.1 11.3 0.4 9.5 1.0 2.3 1 1 0 2 2 2 0 MFS_1 like family PH PF00169.29 CBY34309.1 - 0.11 13.1 0.2 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 PH domain Phage_holin_2_3 PF16080.5 CBY34309.1 - 2 8.3 4.7 1 9.2 0.6 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Maelstrom PF13017.6 CBY34310.1 - 6.1e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 CBY34310.1 - 1.9e-07 31.6 0.1 3.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CBY34310.1 - 0.005 17.2 0.5 0.012 16.0 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box TMEM232 PF15877.5 CBY34311.1 - 7.3e-07 28.5 0.7 1.2e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein family 232 Tektin PF03148.14 CBY34312.1 - 7.9e-128 426.4 30.5 9.6e-128 426.2 30.5 1.1 1 0 0 1 1 1 1 Tektin family Exonuc_VII_L PF02601.15 CBY34312.1 - 1.2 8.6 18.6 1.4 8.4 4.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit TolA_bind_tri PF16331.5 CBY34312.1 - 1.7 8.8 13.8 0.54 10.4 6.7 3.1 2 1 0 2 2 2 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 CBY34312.1 - 3.3 8.2 11.4 5.7 7.4 0.7 3.5 3 0 0 3 3 3 0 Snapin/Pallidin DUF2205 PF10224.9 CBY34312.1 - 4.5 7.3 7.6 0.93 9.5 1.5 2.8 2 0 0 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 CBY34312.1 - 5.9 6.7 17.1 0.42 10.4 2.0 4.1 4 0 0 4 4 4 0 Septum formation initiator Trypsin PF00089.26 CBY34313.1 - 2.8e-45 154.8 0.1 6.2e-45 153.7 0.1 1.6 1 0 0 1 1 1 1 Trypsin TSP_1 PF00090.19 CBY34313.1 - 6.9e-42 141.4 93.9 1e-08 35.3 5.9 6.9 6 0 0 6 6 6 6 Thrombospondin type 1 domain Pentaxin PF00354.17 CBY34313.1 - 6.8e-18 65.1 1.1 1.8e-12 47.3 0.0 3.9 4 1 0 4 4 4 2 Pentaxin family Laminin_G_3 PF13385.6 CBY34313.1 - 3.3e-15 56.6 0.0 1.2e-06 28.7 0.0 3.0 2 1 1 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily CUB PF00431.20 CBY34313.1 - 3.3e-14 53.1 0.3 1.6e-12 47.7 0.1 2.7 1 1 1 2 2 2 1 CUB domain CUB PF00431.20 CBY34314.1 - 7e-17 61.8 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 CUB domain DUF2627 PF11118.8 CBY34315.1 - 0.061 13.9 2.0 0.061 13.9 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Yippee-Mis18 PF03226.14 CBY34316.1 - 6e-06 26.4 1.3 7.7e-06 26.1 1.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CBY34316.1 - 0.21 11.8 1.7 0.61 10.3 1.7 1.7 1 1 0 1 1 1 0 C-terminal domain of RIG-I Baculo_LEF5_C PF11792.8 CBY34316.1 - 2.1 8.1 6.4 0.26 11.0 1.3 2.1 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain XPG_N PF00752.17 CBY34317.1 - 8.6e-17 61.5 0.0 2.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain LOH1CR12 PF10158.9 CBY34317.1 - 1.9e-10 40.9 0.2 3.1e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Tumour suppressor protein XPG_I PF00867.18 CBY34317.1 - 2.1e-07 31.2 0.2 6.3e-07 29.7 0.2 2.0 1 1 0 1 1 1 1 XPG I-region Baculo_PEP_C PF04513.12 CBY34317.1 - 1.1e-05 25.6 1.8 1.8e-05 24.8 1.8 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CBY34317.1 - 0.00082 19.4 2.3 0.002 18.2 2.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 CBY34317.1 - 0.0047 17.3 2.1 0.0094 16.3 2.1 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Snf7 PF03357.21 CBY34317.1 - 0.046 13.3 8.1 0.027 14.1 3.2 2.1 2 0 0 2 2 2 0 Snf7 NPV_P10 PF05531.12 CBY34317.1 - 0.056 13.9 1.0 0.4 11.2 1.0 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Bap31_Bap29_C PF18035.1 CBY34317.1 - 0.061 13.3 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Laminin_II PF06009.12 CBY34317.1 - 0.071 13.1 3.2 0.77 9.8 3.2 2.3 1 1 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.11 CBY34317.1 - 0.2 12.1 2.9 7.7 7.0 0.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 CBY34317.1 - 0.28 10.4 2.2 0.43 9.8 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 CBY34317.1 - 0.61 10.1 4.9 0.39 10.8 0.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 CBY34318.1 - 5.6e-51 173.4 0.0 1.1e-43 149.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34318.1 - 8.4e-28 97.4 0.1 1.5e-24 86.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY34318.1 - 4.3e-07 29.5 0.2 2.5e-06 27.0 0.2 2.3 1 1 0 1 1 1 1 Kinase-like PBD PF00786.28 CBY34318.1 - 8.2e-06 26.1 1.3 3.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CBY34318.1 - 0.00043 19.2 0.6 0.0012 17.8 0.6 1.8 1 1 0 1 1 1 1 Fungal protein kinase FAM163 PF15069.6 CBY34318.1 - 0.073 13.5 0.7 0.13 12.7 0.7 1.5 1 1 0 1 1 1 0 FAM163 family PCI PF01399.27 CBY34319.1 - 4.3e-09 36.8 0.4 4.3e-09 36.8 0.4 3.4 4 0 0 4 4 4 1 PCI domain MtrG PF04210.13 CBY34319.1 - 2.9 7.8 4.5 2.2 8.2 1.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ALMT PF11744.8 CBY34320.1 - 4.7 5.9 9.1 5.7 5.7 9.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 CBY34321.1 - 3.5e-41 141.3 0.0 9.7e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34321.1 - 2.9e-24 85.7 0.0 6.6e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 CBY34321.1 - 9.1e-05 22.5 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Ras PF00071.22 CBY34322.1 - 5e-49 166.0 0.0 5.8e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY34322.1 - 2.3e-30 105.3 0.0 4.5e-30 104.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY34322.1 - 3.1e-10 39.8 0.0 4.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY34322.1 - 0.00015 21.8 0.0 0.00028 21.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBY34322.1 - 0.00018 21.8 0.1 0.00092 19.6 0.1 2.0 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CBY34322.1 - 0.0035 17.1 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CBY34322.1 - 0.0044 16.4 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY34322.1 - 0.0077 15.8 0.2 0.029 13.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 CBY34322.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute G-alpha PF00503.20 CBY34322.1 - 0.016 14.4 1.0 1.7 7.8 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 CBY34322.1 - 0.026 14.4 0.1 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 CBY34322.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.12 CBY34322.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.18 CBY34322.1 - 0.056 12.7 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CBY34322.1 - 0.071 13.5 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBY34322.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBY34322.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY34322.1 - 0.18 11.0 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2142 PF09913.9 CBY34323.1 - 0.098 11.5 0.2 0.4 9.5 0.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) POX PF07526.11 CBY34324.1 - 0.026 15.1 0.0 0.054 14.1 0.0 1.5 2 0 0 2 2 2 0 Associated with HOX MLANA PF14991.6 CBY34324.1 - 0.041 14.2 1.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A Cullin_Nedd8 PF10557.9 CBY34325.1 - 4.9e-20 71.3 0.5 5.4e-20 71.2 0.5 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_rep_org_N PF09681.10 CBY34325.1 - 0.013 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) TrmB PF01978.19 CBY34325.1 - 0.026 14.4 0.1 0.031 14.2 0.1 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FAM86 PF14904.6 CBY34325.1 - 0.03 14.4 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function Penicillinase_R PF03965.16 CBY34325.1 - 0.077 13.4 0.1 0.084 13.2 0.1 1.1 1 0 0 1 1 1 0 Penicillinase repressor Cullin PF00888.22 CBY34326.1 - 5.7e-152 507.5 6.6 6.6e-152 507.3 6.6 1.0 1 0 0 1 1 1 1 Cullin family MarR_2 PF12802.7 CBY34326.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 MarR family SpoIIE PF07228.12 CBY34327.1 - 4.1e-16 59.5 0.0 5.4e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBY34327.1 - 1.4e-07 31.4 0.0 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CBY34327.1 - 0.00027 20.6 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C zf-C3HC PF07967.13 CBY34327.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 C3HC zinc finger-like DUF1043 PF06295.12 CBY34328.1 - 0.88 9.6 0.0 0.88 9.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF4407 PF14362.6 CBY34328.1 - 6.4 6.0 16.8 0.75 9.1 9.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF4579 PF15158.6 CBY34329.1 - 9e-72 240.7 3.0 1.1e-71 240.5 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF3958 PF13125.6 CBY34330.1 - 0.01 16.0 0.8 0.015 15.5 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) SPT16 PF08644.11 CBY34330.1 - 0.076 13.2 2.7 0.1 12.8 2.7 1.1 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) SPT2 PF08243.11 CBY34330.1 - 0.37 11.3 5.7 15 6.1 5.7 2.0 1 1 0 1 1 1 0 SPT2 chromatin protein DUF3040 PF11239.8 CBY34331.1 - 2.5 8.5 4.8 2.6 8.4 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Fib_alpha PF08702.10 CBY34331.1 - 3.3 7.9 18.0 6.4 7.0 4.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 CBY34332.1 - 0.0041 17.2 7.5 0.0041 17.2 7.5 11.1 4 2 6 11 11 11 1 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.12 CBY34332.1 - 6.8 6.7 10.9 4.4 7.3 0.1 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SAWADEE PF16719.5 CBY34332.1 - 9.6 6.2 14.4 4.7 7.2 3.2 3.7 3 0 0 3 3 3 0 SAWADEE domain Alg6_Alg8 PF03155.15 CBY34334.1 - 4.3e-127 425.0 34.7 4.3e-127 425.0 34.7 1.5 2 0 0 2 2 2 1 ALG6, ALG8 glycosyltransferase family Ig_mannosidase PF17753.1 CBY34334.1 - 4.5e-07 29.5 0.1 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2 PF00703.21 CBY34334.1 - 0.00012 22.7 0.0 0.00026 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ABC_tran PF00005.27 CBY34336.1 - 7.1e-35 120.5 0.0 3.9e-23 82.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBY34336.1 - 3.1e-14 53.5 4.9 0.00028 20.8 0.0 3.7 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY34336.1 - 6e-11 42.2 0.0 0.0004 19.9 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY34336.1 - 1e-08 34.8 0.1 0.00097 18.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY34336.1 - 3.7e-08 33.5 0.0 0.0061 16.6 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CBY34336.1 - 4e-08 34.0 0.4 0.0047 17.4 0.1 2.6 3 0 0 3 3 2 2 AAA domain ABC_tran_Xtn PF12848.7 CBY34336.1 - 5.5e-08 32.7 0.0 9.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CBY34336.1 - 2.5e-07 31.1 0.2 0.0017 18.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CBY34336.1 - 6.6e-07 29.4 0.3 0.0095 15.9 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY34336.1 - 4.7e-06 27.1 0.0 0.0041 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 CBY34336.1 - 1e-05 25.4 0.1 0.05 13.3 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_28 PF13521.6 CBY34336.1 - 1.4e-05 25.4 0.1 0.1 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBY34336.1 - 2.1e-05 24.3 0.2 0.045 13.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 CBY34336.1 - 8.4e-05 22.8 0.2 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 CBY34336.1 - 0.0001 21.4 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBY34336.1 - 0.00011 22.3 0.1 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 CBY34336.1 - 0.00014 21.6 0.0 0.2 11.3 0.0 2.5 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CBY34336.1 - 0.0002 21.9 0.0 0.57 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CBY34336.1 - 0.00023 21.1 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 CBY34336.1 - 0.00027 20.6 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBY34336.1 - 0.00034 19.9 0.0 0.051 12.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CBY34336.1 - 0.00065 19.3 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBY34336.1 - 0.00096 19.3 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBY34336.1 - 0.0046 17.3 0.0 0.99 9.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 CBY34336.1 - 0.0046 16.6 0.4 3 7.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CBY34336.1 - 0.0082 16.4 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CBY34336.1 - 0.0091 16.0 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 CBY34336.1 - 0.012 15.0 0.3 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF2813 PF11398.8 CBY34336.1 - 0.013 14.8 0.0 0.94 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DUF815 PF05673.13 CBY34336.1 - 0.013 14.6 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arf PF00025.21 CBY34336.1 - 0.016 14.6 0.0 0.85 9.0 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_13 PF13166.6 CBY34336.1 - 0.019 13.7 0.1 3.4 6.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CBY34336.1 - 0.019 14.9 0.0 5.8 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MobB PF03205.14 CBY34336.1 - 0.024 14.5 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 CBY34336.1 - 0.037 13.3 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 CBY34336.1 - 0.043 13.0 0.1 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain dNK PF01712.19 CBY34336.1 - 0.046 13.6 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 CBY34336.1 - 0.049 13.6 0.1 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CBY34336.1 - 0.061 13.8 0.0 14 6.1 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 CBY34336.1 - 0.075 13.3 0.2 1.3 9.4 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 CBY34336.1 - 0.075 12.9 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 CBY34336.1 - 0.1 11.4 0.2 6.8 5.4 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 CBY34336.1 - 0.11 12.6 0.0 8.8 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CBY34336.1 - 0.13 12.0 0.2 20 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CBY34336.1 - 0.15 11.7 0.2 24 4.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 CBY34336.1 - 0.16 11.1 0.1 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 CBY34336.1 - 0.16 11.8 0.0 5.9 6.7 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 CBY34336.1 - 0.17 11.5 0.0 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase DUF3584 PF12128.8 CBY34336.1 - 0.18 9.2 1.2 1.7 6.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Adeno_IVa2 PF02456.15 CBY34336.1 - 0.19 10.5 0.0 2.4 6.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein CLP1_P PF16575.5 CBY34336.1 - 0.21 11.4 0.4 16 5.2 0.1 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Rap_GAP PF02145.15 CBY34337.1 - 7.2e-18 64.8 0.0 1.8e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP RRM_1 PF00076.22 CBY34338.1 - 1.7e-14 53.3 0.0 2.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY34338.1 - 0.077 13.0 0.1 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UEV PF05743.13 CBY34339.1 - 2.5e-37 127.4 0.0 5e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CBY34339.1 - 2.3e-21 75.5 0.3 1.4e-20 72.9 0.1 2.1 2 0 0 2 2 2 1 Vps23 core domain Fmp27_WPPW PF10359.9 CBY34339.1 - 0.0073 15.2 3.2 0.011 14.6 3.2 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain FOXP-CC PF16159.5 CBY34339.1 - 0.016 15.8 0.1 0.95 10.1 0.1 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF4200 PF13863.6 CBY34339.1 - 0.16 12.4 9.9 0.093 13.1 6.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 CBY34339.1 - 0.19 11.0 2.9 0.099 11.9 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KxDL PF10241.9 CBY34339.1 - 0.64 10.3 3.3 0.74 10.1 0.8 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein TMPIT PF07851.13 CBY34339.1 - 0.66 9.2 3.9 0.57 9.4 1.8 1.7 2 0 0 2 2 2 0 TMPIT-like protein Occludin_ELL PF07303.13 CBY34339.1 - 2.4 8.9 4.9 28 5.5 0.2 2.5 2 0 0 2 2 2 0 Occludin homology domain Prefoldin_2 PF01920.20 CBY34339.1 - 7.8 6.5 8.5 0.8 9.7 2.4 2.3 2 1 1 3 3 3 0 Prefoldin subunit UQ_con PF00179.26 CBY34340.1 - 2.1e-09 37.2 0.0 6.4e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY34340.1 - 0.019 15.3 0.0 0.041 14.2 0.0 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CBY34340.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B TBCA PF02970.16 CBY34340.1 - 0.49 10.7 4.1 12 6.3 0.4 2.8 3 0 0 3 3 3 0 Tubulin binding cofactor A Exo_endo_phos PF03372.23 CBY34341.1 - 5.7e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBY34341.1 - 0.17 11.7 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Sulfatase PF00884.23 CBY34342.1 - 3e-30 105.7 0.0 4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY34342.1 - 1.2e-26 93.8 0.0 2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 CBY34342.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metallophos PF00149.28 CBY34343.1 - 5.4e-16 59.7 1.0 7.1e-16 59.3 1.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2428 PF10350.9 CBY34344.1 - 4.3e-60 203.3 0.2 1.1e-59 202.0 0.1 1.8 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 CBY34345.1 - 3.1e-05 24.3 1.0 0.48 10.9 0.0 3.6 2 1 2 4 4 4 2 HEAT repeats TAF6_C PF07571.13 CBY34345.1 - 0.0012 19.1 0.0 0.005 17.1 0.0 2.0 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CBY34345.1 - 0.034 14.4 0.8 45 4.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat TSP_1 PF00090.19 CBY34346.1 - 1.6e-12 47.4 26.8 4.6e-08 33.2 8.6 3.0 2 1 0 2 2 2 2 Thrombospondin type 1 domain TMEM154 PF15102.6 CBY34346.1 - 0.00017 21.5 0.2 0.00044 20.2 0.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF3439 PF11921.8 CBY34346.1 - 0.0043 17.0 6.9 0.0094 15.9 5.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF3377 PF11857.8 CBY34346.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Mucin PF01456.17 CBY34346.1 - 0.59 10.1 12.4 1.3 9.0 12.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 CBY34347.1 - 1.2e-37 129.8 0.0 1.5e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY34347.1 - 2.9e-11 43.2 0.3 4.2e-08 32.9 0.1 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.17 CBY34347.1 - 7.4e-08 32.0 0.0 8.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY34347.1 - 4.5e-05 22.9 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY34347.1 - 8.2e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY34347.1 - 0.005 16.4 0.5 0.0085 15.7 0.4 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF1187 PF06688.11 CBY34347.1 - 0.11 12.9 0.3 0.99 9.8 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1187) EGF_CA PF07645.15 CBY34348.1 - 3.7e-10 39.9 8.1 3.7e-10 39.9 8.1 8.4 10 1 0 10 10 10 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY34348.1 - 0.00099 19.3 3.6 0.00099 19.3 3.6 8.8 7 2 1 8 8 8 2 EGF domain hEGF PF12661.7 CBY34348.1 - 0.019 15.6 1.5 0.019 15.6 1.5 8.7 9 2 0 9 9 9 0 Human growth factor-like EGF cEGF PF12662.7 CBY34348.1 - 0.1 12.5 0.2 0.1 12.5 0.2 6.4 6 0 0 6 6 6 0 Complement Clr-like EGF-like RepA_C PF04796.12 CBY34349.1 - 0.02 14.9 0.9 0.02 14.9 0.9 2.5 1 1 1 2 2 2 0 Plasmid encoded RepA protein CheX PF13690.6 CBY34349.1 - 0.5 10.6 2.2 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Chemotaxis phosphatase CheX TPH PF13868.6 CBY34349.1 - 2.8 6.4 122.1 0.0031 16.1 92.4 2.9 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain Pkinase PF00069.25 CBY34350.1 - 5e-46 157.2 0.0 6.3e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34350.1 - 2.6e-27 95.7 0.0 3.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34350.1 - 1.5e-09 37.6 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY34350.1 - 0.035 13.4 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_Nse1 PF07574.13 CBY34350.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex TMC PF07810.13 CBY34352.1 - 4.3e-26 91.7 0.1 5.4e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 TMC domain zf-C2H2 PF00096.26 CBY34353.1 - 1.1e-15 57.1 31.3 0.00022 21.5 3.9 5.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY34353.1 - 5.2e-13 48.8 30.3 3.6e-07 30.3 1.8 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY34353.1 - 1e-06 29.1 30.5 0.011 16.5 0.7 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY34353.1 - 2e-06 28.3 28.2 0.013 16.1 1.0 6.1 2 1 4 6 6 6 4 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CBY34353.1 - 0.061 13.3 14.5 0.66 10.1 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CBY34353.1 - 0.14 12.6 11.6 11 6.6 1.0 4.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CBY34353.1 - 0.91 9.6 12.8 12 6.0 0.3 3.9 1 1 2 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CBY34353.1 - 0.93 9.9 14.8 2.7 8.4 0.7 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding SET PF00856.28 CBY34355.1 - 3.4e-09 37.3 0.2 2e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 SET domain PurL_C PF16904.5 CBY34355.1 - 0.1 12.9 0.5 0.62 10.4 0.1 2.4 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus DHFR_1 PF00186.19 CBY34356.1 - 5.2e-05 23.0 0.0 6.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase fn2 PF00040.19 CBY34356.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type II domain MerR PF00376.23 CBY34358.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.0 2 0 0 2 2 2 0 MerR family regulatory protein PDDEXK_10 PF07788.11 CBY34358.1 - 0.14 12.1 0.8 0.68 9.9 0.1 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily zf-rbx1 PF12678.7 CBY34359.1 - 2.9e-13 49.9 8.0 7.4e-13 48.6 8.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBY34359.1 - 1.6e-10 41.1 5.3 3e-10 40.3 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CBY34359.1 - 4.2e-08 33.1 7.1 1.1e-07 31.8 7.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY34359.1 - 1.1e-07 31.6 4.2 2e-07 30.7 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY34359.1 - 1.1e-06 28.4 4.7 2.1e-06 27.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY34359.1 - 2.5e-05 24.2 3.3 4e-05 23.5 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY34359.1 - 0.00033 20.4 4.5 0.00076 19.3 4.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY34359.1 - 0.00042 20.3 0.9 0.00086 19.3 0.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CBY34359.1 - 0.00044 19.9 0.5 0.00087 19.0 0.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBY34359.1 - 0.0013 18.5 4.9 0.0077 16.1 5.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY34359.1 - 0.0064 16.1 3.9 0.011 15.3 3.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBY34359.1 - 0.016 15.1 4.0 0.034 14.0 4.0 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CBY34359.1 - 0.045 13.7 3.3 0.17 11.8 3.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2590 PF10761.9 CBY34359.1 - 0.066 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) zf-RING_9 PF13901.6 CBY34359.1 - 0.095 12.7 1.7 0.25 11.3 1.7 1.7 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 CBY34359.1 - 0.11 12.7 5.1 0.27 11.5 5.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2149 PF09919.9 CBY34359.1 - 0.17 12.1 0.3 0.67 10.2 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) zf-RING_4 PF14570.6 CBY34359.1 - 0.23 11.3 3.4 0.45 10.3 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 CBY34359.1 - 0.58 10.3 2.7 0.52 10.5 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger RINGv PF12906.7 CBY34359.1 - 1.6 8.9 5.9 2.8 8.1 5.5 1.7 1 1 0 1 1 1 0 RING-variant domain Wtap PF17098.5 CBY34360.1 - 2.4e-50 170.5 15.5 2.4e-50 170.5 15.5 3.6 3 1 1 4 4 4 1 WTAP/Mum2p family BTB PF00651.31 CBY34360.1 - 4.4e-13 49.4 0.0 7.5e-12 45.5 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain HALZ PF02183.18 CBY34360.1 - 0.0071 16.5 2.1 1.2 9.4 0.1 4.0 3 0 0 3 3 3 1 Homeobox associated leucine zipper AAA_13 PF13166.6 CBY34360.1 - 0.55 8.8 17.8 0.94 8.0 17.8 1.3 1 0 0 1 1 1 0 AAA domain Peripla_BP_2 PF01497.18 CBY34360.1 - 1.7 8.2 4.6 0.66 9.5 1.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein ATG16 PF08614.11 CBY34360.1 - 1.8 8.8 34.0 1.3 9.2 19.1 2.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Sod_Fe_C PF02777.18 CBY34362.1 - 2.1e-36 124.1 0.1 3.9e-36 123.3 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBY34362.1 - 2.3e-32 111.3 2.1 3.9e-32 110.5 2.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATE_C PF04377.15 CBY34363.1 - 2.1e-45 154.7 6.7 3.4e-45 154.0 6.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CBY34363.1 - 6.6e-25 87.3 2.3 6.6e-25 87.3 2.3 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus DUF5456 PF17539.2 CBY34363.1 - 0.22 11.4 1.5 0.54 10.1 1.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5456) IP_trans PF02121.18 CBY34364.1 - 8.5e-102 339.9 0.1 1e-101 339.7 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein CRS1_YhbY PF01985.21 CBY34364.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain ADH_zinc_N PF00107.26 CBY34365.1 - 1.8e-07 31.2 0.0 1.1e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY34365.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 CBY34365.1 - 0.029 14.6 0.1 0.081 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_N PF08240.12 CBY34365.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.14 CBY34365.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CBY34365.1 - 0.1 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 CBY34365.1 - 0.12 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SAS-6_N PF16531.5 CBY34366.1 - 1e-20 74.1 6.3 1.1e-19 70.8 0.3 2.9 3 0 0 3 3 3 2 Centriolar protein SAS N-terminal Choline_kinase PF01633.20 CBY34367.1 - 9.9e-20 71.0 1.4 3.7e-19 69.2 0.8 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CBY34367.1 - 1.4e-06 28.4 0.2 9.1e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY34367.1 - 4.4e-05 22.9 0.4 6.3e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CBY34367.1 - 0.0056 15.6 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CBY34368.1 - 1.6e-17 63.8 0.0 2.1e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.19 CBY34368.1 - 0.0011 19.0 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Choline_kinase PF01633.20 CBY34369.1 - 4.7e-24 85.2 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY34369.1 - 8.1e-08 32.5 0.0 1.4e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY34369.1 - 6.8e-06 25.6 0.0 8.7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CBY34369.1 - 0.051 12.4 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CBY34370.1 - 7.1e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase CTP_transf_3 PF02348.19 CBY34370.1 - 0.022 14.7 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase Sld7_N PF18636.1 CBY34370.1 - 0.055 13.8 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain WD40 PF00400.32 CBY34371.1 - 8.3e-14 51.8 2.7 0.1 13.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34371.1 - 2.2e-08 34.3 0.5 1.2 9.5 0.0 5.7 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Pre-PUA PF17832.1 CBY34372.1 - 2.1e-25 89.2 1.3 2.9e-25 88.8 1.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CBY34372.1 - 1.5e-14 53.7 0.1 2.3e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 PUA domain Ras PF00071.22 CBY34373.1 - 1.5e-52 177.4 0.1 2e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY34373.1 - 5.4e-29 100.8 0.0 8.9e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY34373.1 - 1.5e-09 37.6 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY34373.1 - 0.00013 21.5 0.1 0.00044 19.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY34373.1 - 0.0014 18.5 0.1 0.4 10.6 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase DUF2294 PF10057.9 CBY34373.1 - 0.079 13.1 0.4 0.75 9.9 0.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) AAA_16 PF13191.6 CBY34373.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF4490 PF14892.6 CBY34375.1 - 3.7e-05 23.7 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CBM_2 PF00553.19 CBY34376.1 - 0.00054 20.2 4.1 0.0041 17.4 1.3 2.3 2 0 0 2 2 2 2 Cellulose binding domain RabGAP-TBC PF00566.18 CBY34377.1 - 8.1e-56 189.1 0.6 2.1e-55 187.7 0.6 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3694 PF12473.8 CBY34377.1 - 1.8e-22 80.6 0.0 4.1e-21 76.2 0.0 2.8 2 1 0 2 2 2 1 Kinesin protein Ig_GlcNase PF18368.1 CBY34377.1 - 0.00012 22.1 0.0 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain PID PF00640.23 CBY34377.1 - 0.0088 16.1 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DUF1664 PF07889.12 CBY34377.1 - 2.4 8.2 5.6 0.76 9.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sfi1_C PF10638.9 CBY34377.1 - 3.8 8.3 8.0 0.89 10.3 0.7 3.0 3 0 0 3 3 3 0 Spindle body associated protein C-terminus Sid-5 PF17204.3 CBY34378.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Sid-5 family EAP30 PF04157.16 CBY34379.1 - 6.3e-58 195.9 0.0 7.3e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family CENP-H PF05837.12 CBY34379.1 - 0.015 15.7 0.2 0.029 14.8 0.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) WH1 PF00568.23 CBY34382.1 - 9.7e-14 51.3 0.1 1.3e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 WH1 domain I-set PF07679.16 CBY34383.1 - 6e-46 154.5 0.3 9.3e-13 48.1 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.21 CBY34383.1 - 2.9e-32 110.9 0.0 8.8e-13 48.4 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 CBY34383.1 - 1e-26 93.3 0.1 4.5e-11 43.2 0.0 6.3 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 CBY34383.1 - 3.4e-12 46.5 0.2 9.7e-06 25.8 0.1 5.1 6 0 0 6 6 6 2 Immunoglobulin domain V-set PF07686.17 CBY34383.1 - 7.7e-11 42.1 2.7 0.14 12.3 0.1 5.8 5 1 1 6 6 6 3 Immunoglobulin V-set domain ig PF00047.25 CBY34383.1 - 2.5e-08 34.0 0.2 0.00029 21.0 0.0 4.2 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 CBY34383.1 - 0.0023 17.9 4.6 3.5 7.8 0.0 4.9 6 0 0 6 6 5 1 Izumo-like Immunoglobulin domain EF-hand_1 PF00036.32 CBY34383.1 - 0.013 15.0 0.3 0.04 13.5 0.3 1.9 1 0 0 1 1 1 0 EF hand C2-set_2 PF08205.12 CBY34383.1 - 0.022 14.8 0.3 0.47 10.6 0.0 2.8 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain EF-hand_5 PF13202.6 CBY34383.1 - 0.023 14.2 0.5 0.069 12.7 0.5 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.8 CBY34383.1 - 0.048 13.9 0.0 12 6.1 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EF-hand_8 PF13833.6 CBY34383.1 - 0.09 12.6 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Ribophorin_II PF05817.14 CBY34383.1 - 0.31 9.5 0.4 1.4 7.4 0.1 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II RT_RNaseH PF17917.1 CBY34384.1 - 1.1e-28 99.6 0.0 2.3e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY34384.1 - 5.1e-27 93.8 0.0 1.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY34384.1 - 2.4e-13 50.3 0.0 9.7e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 CBY34384.1 - 6.8e-10 38.8 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY34384.1 - 7.5e-06 26.0 0.1 1.7e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Prot_ATP_OB_N PF17758.1 CBY34384.1 - 0.035 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain WIF PF02019.18 CBY34384.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 WIF domain Trypsin PF00089.26 CBY34388.1 - 2.1e-26 93.1 0.4 2.5e-26 92.9 0.4 1.0 1 0 0 1 1 1 1 Trypsin FA_hydroxylase PF04116.13 CBY34390.1 - 6.6e-23 81.5 13.9 6.6e-23 81.5 13.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EMC1_C PF07774.13 CBY34390.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Histone PF00125.24 CBY34391.1 - 1.2e-50 171.3 2.0 1.3e-50 171.1 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY34391.1 - 0.00017 21.6 0.5 0.00026 21.1 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY34391.1 - 0.00078 20.0 1.4 0.00086 19.9 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY34391.1 - 0.0008 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY34391.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sirohm_synth_M PF14824.6 CBY34391.1 - 1.3 8.6 3.8 4.7 6.8 0.4 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Histone PF00125.24 CBY34392.1 - 7.5e-17 61.9 0.7 9.9e-17 61.5 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY34392.1 - 0.00043 20.5 0.9 0.00093 19.4 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 CBY34393.1 - 4.4e-16 58.3 0.9 4.4e-16 58.3 0.9 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CBY34393.1 - 5e-15 56.0 0.0 6.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY34393.1 - 3.4e-06 27.2 0.0 5.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CSD PF00313.22 CBY34398.1 - 4.1e-08 33.0 0.1 7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Chalcone_N PF18232.1 CBY34398.1 - 0.14 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain Shugoshin_C PF07557.11 CBY34399.1 - 1e-09 38.0 3.9 1e-09 38.0 3.9 3.2 2 0 0 2 2 2 1 Shugoshin C terminus NTF2 PF02136.20 CBY34400.1 - 3.2e-26 92.3 0.0 3.6e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CBY34400.1 - 0.03 14.7 0.0 0.037 14.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Glycos_transf_2 PF00535.26 CBY34402.1 - 3e-24 85.7 0.0 3.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY34402.1 - 3.9e-10 40.0 0.0 5.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CBY34402.1 - 4e-09 36.4 0.0 5.2e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CBY34402.1 - 0.0036 17.8 0.0 0.0069 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CAP59_mtransfer PF11735.8 CBY34402.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 Synuclein PF01387.17 CBY34403.1 - 0.13 12.5 0.9 1.9 8.7 0.1 2.4 2 1 0 2 2 2 0 Synuclein TPR_12 PF13424.6 CBY34404.1 - 3.6e-19 68.8 48.2 0.0011 19.3 0.4 10.9 8 2 3 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 CBY34404.1 - 2.5e-16 58.7 7.5 0.0063 16.3 0.1 10.7 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY34404.1 - 9.9e-15 53.5 11.9 0.0047 17.0 0.1 10.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY34404.1 - 2.7e-14 52.0 27.8 0.0065 16.5 0.2 12.1 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY34404.1 - 1.2e-10 40.6 22.2 0.00066 19.5 0.2 9.5 11 1 0 11 11 9 3 Tetratricopeptide repeat TPR_4 PF07721.14 CBY34404.1 - 1.9e-09 37.2 22.3 0.19 12.5 0.4 9.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY34404.1 - 3.6e-09 37.1 30.7 0.00087 19.9 4.3 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY34404.1 - 1.4e-07 31.7 39.4 0.1 13.5 0.1 12.5 13 1 0 13 13 13 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY34404.1 - 1.3e-05 24.7 30.4 0.0079 15.6 0.1 4.4 2 1 3 5 5 5 4 MalT-like TPR region ANAPC3 PF12895.7 CBY34404.1 - 2.8e-05 24.2 32.6 0.0029 17.8 0.9 8.2 6 2 3 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 CBY34404.1 - 0.00026 21.0 7.1 0.00074 19.5 0.2 4.2 4 1 1 5 5 5 1 Putative TPR-like repeat TPR_19 PF14559.6 CBY34404.1 - 0.00058 20.3 4.9 0.0041 17.6 0.8 10.0 7 3 3 11 11 11 2 Tetratricopeptide repeat PhageMin_Tail PF10145.9 CBY34404.1 - 0.00072 19.5 2.4 0.0015 18.5 0.3 2.4 2 0 0 2 2 2 1 Phage-related minor tail protein TPR_6 PF13174.6 CBY34404.1 - 0.0013 19.3 21.7 0.35 11.6 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY34404.1 - 0.025 14.5 36.8 0.67 9.9 0.2 10.5 12 0 0 12 12 11 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY34404.1 - 0.032 14.3 0.3 0.61 10.2 0.0 3.3 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region GDH_N PF12466.8 CBY34404.1 - 0.075 13.2 0.1 0.26 11.5 0.1 1.9 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Clathrin PF00637.20 CBY34404.1 - 0.088 12.7 14.0 0.74 9.7 2.7 4.9 4 2 3 7 7 7 0 Region in Clathrin and VPS TPR_17 PF13431.6 CBY34404.1 - 0.2 12.1 7.4 0.45 11.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 CBY34404.1 - 1.2 9.5 21.0 0.9 10.0 0.1 6.2 4 2 3 7 7 7 0 HEAT repeats CAF1A PF12253.8 CBY34405.1 - 4.9e-20 71.5 12.8 4.9e-20 71.5 12.8 7.5 7 2 1 8 8 8 1 Chromatin assembly factor 1 subunit A Lipase PF00151.19 CBY34406.1 - 1.8e-48 165.6 0.0 2.4e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 CBY34406.1 - 0.00086 20.0 0.3 0.0012 19.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY34406.1 - 0.04 13.2 0.1 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RMMBL PF07521.12 CBY34406.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Lipase_3 PF01764.25 CBY34406.1 - 0.13 12.1 0.2 0.29 11.0 0.2 1.6 1 1 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.25 CBY34407.1 - 5.3e-39 134.2 0.0 8.8e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34407.1 - 3e-28 98.8 0.0 4.8e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY34407.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY34407.1 - 0.0044 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY34407.1 - 0.0098 14.9 0.1 0.0098 14.9 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBY34407.1 - 0.065 13.1 0.0 0.85 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY34407.1 - 0.6 8.8 4.6 0.13 11.0 0.2 2.1 2 1 0 2 2 2 0 Fungal protein kinase CH PF00307.31 CBY34408.1 - 6.2e-15 55.3 0.1 6.2e-15 55.3 0.1 2.3 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY34408.1 - 0.0002 21.2 0.0 0.00065 19.5 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain AvrPto PF11592.8 CBY34408.1 - 0.074 13.1 0.4 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto DUF5357 PF17310.2 CBY34408.1 - 2.4 6.6 4.4 4.5 5.7 4.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Ribosomal_L22 PF00237.19 CBY34409.1 - 0.011 15.9 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Csm4_C PF17953.1 CBY34409.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain SH3_1 PF00018.28 CBY34410.1 - 2.9e-14 52.4 0.5 2.9e-14 52.4 0.5 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY34410.1 - 1.4e-11 43.9 0.2 4.6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CBY34410.1 - 1.5e-11 43.9 0.1 3.6e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.20 CBY34410.1 - 0.00021 21.6 0.3 0.00021 21.6 0.3 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF5348 PF17295.2 CBY34410.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) FAM76 PF16046.5 CBY34410.1 - 0.051 12.9 0.7 0.11 11.9 0.7 1.5 1 0 0 1 1 1 0 FAM76 protein Cdh1_DBD_1 PF18196.1 CBY34410.1 - 0.25 11.7 4.8 5.2 7.4 0.1 2.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Rab5-bind PF09311.11 CBY34410.1 - 0.49 9.7 9.3 0.21 10.9 4.3 2.2 2 0 0 2 2 2 0 Rabaptin-like protein Syntaxin-6_N PF09177.11 CBY34410.1 - 0.51 10.9 8.4 1 10.0 2.0 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 CBY34410.1 - 1.9 8.5 9.6 0.088 12.9 2.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 CBY34410.1 - 3.1 6.3 12.0 0.64 8.5 7.6 1.8 2 0 0 2 2 2 0 Macoilin family MFS_2 PF13347.6 CBY34411.1 - 3.8e-15 55.4 25.8 1.8e-13 49.8 25.8 2.5 1 1 0 1 1 1 1 MFS/sugar transport protein Pam16 PF03656.13 CBY34412.1 - 5.3e-05 23.2 8.1 5.9e-05 23.1 7.5 1.5 1 1 0 1 1 1 1 Pam16 Indigoidine_A PF04227.12 CBY34412.1 - 0.025 14.0 3.8 0.047 13.0 3.8 1.5 1 1 0 1 1 1 0 Indigoidine synthase A like protein ProSAAS PF07259.12 CBY34412.1 - 5.8 6.8 7.7 1.8 8.5 1.7 2.0 2 0 0 2 2 2 0 ProSAAS precursor Glycos_transf_2 PF00535.26 CBY34413.1 - 2.3e-25 89.4 0.0 3.9e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY34413.1 - 5.5e-19 68.7 4.8 8.9e-19 68.0 4.8 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.9 CBY34413.1 - 1.3e-05 24.8 0.2 0.00032 20.2 0.2 2.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 CBY34413.1 - 7.6e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 CBY34413.1 - 0.00023 20.8 3.0 0.00071 19.2 0.1 2.5 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.6 CBY34413.1 - 0.2 12.4 6.9 2.2 9.1 0.1 3.0 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like UCH PF00443.29 CBY34415.1 - 4.1e-69 232.9 0.0 1.1e-66 225.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY34415.1 - 2.2e-20 73.5 0.0 2.6e-19 70.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 CBY34415.1 - 2.7e-07 30.8 0.5 7.4e-07 29.4 0.5 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain WW PF00397.26 CBY34415.1 - 1.3e-06 28.4 1.2 3.3e-06 27.1 1.2 1.8 1 0 0 1 1 1 1 WW domain LCD1 PF09798.9 CBY34415.1 - 6.6 5.1 7.2 12 4.2 7.2 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein Cyclin_C_2 PF16899.5 CBY34416.1 - 2.2e-18 66.5 0.0 3.7e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CBY34416.1 - 1.9e-10 40.6 0.1 4.1e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY34416.1 - 0.054 13.6 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain SPATA48 PF15073.6 CBY34419.1 - 1.5e-06 28.5 0.9 3.5e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Pkinase PF00069.25 CBY34421.1 - 7.9e-45 153.3 0.0 9.9e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34421.1 - 2e-21 76.5 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34421.1 - 1.3e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY34421.1 - 1.9e-05 23.8 0.5 2.9e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY34421.1 - 4e-05 23.7 0.2 0.00073 19.5 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY34421.1 - 5.9e-05 22.7 1.7 9.2e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBY34421.1 - 9.8e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY34421.1 - 0.0015 17.9 1.0 0.0026 17.2 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5492 PF17596.2 CBY34421.1 - 0.039 14.3 1.3 0.11 12.9 1.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Kinase-PolyVal PF18762.1 CBY34421.1 - 0.12 12.3 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 CBY34421.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 wnt PF00110.19 CBY34422.1 - 2e-44 152.4 7.1 2.6e-44 152.1 7.1 1.1 1 0 0 1 1 1 1 wnt family Connexin PF00029.19 CBY34423.1 - 4e-48 164.2 4.1 5.1e-48 163.9 4.1 1.1 1 0 0 1 1 1 1 Connexin Sulfotransfer_2 PF03567.14 CBY34424.1 - 2.3e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY34424.1 - 0.026 14.0 0.1 0.045 13.2 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Imm58 PF15581.6 CBY34424.1 - 0.13 12.3 0.2 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 58 BTB_3 PF16017.5 CBY34424.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain EF-hand_1 PF00036.32 CBY34425.1 - 1.2e-12 46.4 0.8 0.0052 16.2 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY34425.1 - 1.5e-12 47.7 0.1 1.8e-10 41.1 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY34425.1 - 3.5e-11 42.1 0.2 0.0019 18.0 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBY34425.1 - 7.5e-07 28.4 1.7 0.77 9.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY34425.1 - 9.1e-07 28.6 1.9 0.092 12.6 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 CBY34425.1 - 0.0069 16.5 0.0 6.8 7.0 0.0 2.7 3 0 0 3 3 3 2 Dockerin type I domain Pox_F12L PF03337.13 CBY34425.1 - 0.013 13.7 0.0 0.018 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein TssD PF17642.1 CBY34425.1 - 0.016 15.1 0.3 0.042 13.7 0.0 1.8 3 0 0 3 3 3 0 Hemolysin coregulated protein Hcp (TssD) SPARC_Ca_bdg PF10591.9 CBY34425.1 - 0.048 14.0 0.1 7.4 6.9 0.0 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ish1 PF10281.9 CBY34425.1 - 0.089 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HMMR_C PF15908.5 CBY34426.1 - 0.023 15.0 0.5 0.033 14.5 0.5 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal zf-RING_5 PF14634.6 CBY34427.1 - 1.5e-07 31.3 13.6 1.5e-07 31.3 13.6 2.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY34427.1 - 2.8e-07 30.3 11.4 2.8e-07 30.3 11.4 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY34427.1 - 2.4e-06 27.1 6.9 2.4e-06 27.1 6.9 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 CBY34427.1 - 1.1e-05 25.6 13.1 1.1e-05 25.6 13.1 2.1 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY34427.1 - 3e-05 23.9 17.3 3.8e-05 23.6 6.2 3.5 4 0 0 4 4 4 2 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY34427.1 - 0.00056 19.7 12.0 0.0028 17.5 11.0 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY34427.1 - 0.00069 19.4 9.9 0.00069 19.4 9.9 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY34427.1 - 0.00075 19.3 12.0 0.00075 19.3 12.0 2.6 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY34427.1 - 0.009 15.8 13.1 0.009 15.8 13.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 CBY34427.1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 CBY34427.1 - 0.27 11.0 7.5 0.43 10.4 4.3 2.6 2 0 0 2 2 2 0 RING-like zinc finger Baculo_IE-1 PF05290.11 CBY34427.1 - 0.81 9.6 10.8 0.8 9.7 6.4 2.2 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2_7 PF15269.6 CBY34427.1 - 8.5 6.6 12.5 1.4 9.0 1.3 2.9 3 0 0 3 3 2 0 Zinc-finger TSP_1 PF00090.19 CBY34428.1 - 2.4e-07 30.9 6.1 2.4e-07 30.9 6.1 3.6 3 0 0 3 3 3 2 Thrombospondin type 1 domain Ion_trans_2 PF07885.16 CBY34429.1 - 5.4e-30 103.2 21.9 1.1e-16 60.6 4.5 3.3 3 0 0 3 3 3 3 Ion channel IRK PF01007.20 CBY34429.1 - 0.00058 19.7 1.3 0.52 10.1 0.4 2.5 2 0 0 2 2 2 2 Inward rectifier potassium channel transmembrane domain Death PF00531.22 CBY34429.1 - 0.19 11.9 0.1 0.43 10.8 0.1 1.5 1 0 0 1 1 1 0 Death domain SH2 PF00017.24 CBY34430.1 - 0.00052 20.1 0.0 0.0023 18.0 0.0 2.2 1 1 0 1 1 1 1 SH2 domain Syntaxin-6_N PF09177.11 CBY34430.1 - 0.0033 17.9 0.9 0.02 15.4 0.0 2.5 3 0 0 3 3 3 1 Syntaxin 6, N-terminal AAA_12 PF13087.6 CBY34431.1 - 2.9e-45 154.4 0.9 5.5e-45 153.5 0.9 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY34431.1 - 1.3e-06 28.4 0.3 1.3e-06 28.4 0.3 2.3 3 0 0 3 3 3 1 AAA domain U5_2-snRNA_bdg PF10597.9 CBY34431.1 - 0.069 13.2 0.3 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 U5-snRNA binding site 2 of PrP8 HMG_box PF00505.19 CBY34431.1 - 6.2 7.3 7.4 2.7 8.5 0.6 2.7 2 0 0 2 2 2 0 HMG (high mobility group) box PWWP PF00855.17 CBY34433.1 - 3.4e-14 53.0 0.0 8.1e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 PWWP domain Kelch_6 PF13964.6 CBY34434.1 - 0.00023 21.3 1.7 1.2 9.5 0.1 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY34434.1 - 0.0025 17.4 1.1 4.8 6.9 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Tim17 PF02466.19 CBY34435.1 - 2.5e-18 66.5 10.2 3.1e-18 66.2 10.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_transf_22 PF03901.17 CBY34436.1 - 3.3e-45 155.1 24.3 4.4e-45 154.7 24.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family G_glu_transpept PF01019.21 CBY34437.1 - 0.0059 15.4 0.0 0.0099 14.7 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G-patch PF01585.23 CBY34438.1 - 7.9e-15 54.5 1.0 2.4e-14 52.9 1.0 1.9 1 0 0 1 1 1 1 G-patch domain DND1_DSRM PF14709.7 CBY34438.1 - 9.3e-10 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 CBY34438.1 - 2.3e-09 37.8 0.0 5.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif RSRP PF17069.5 CBY34438.1 - 0.00038 20.1 50.9 0.00038 20.1 50.9 2.1 1 1 1 2 2 2 1 Arginine/Serine-Rich protein 1 G-patch_2 PF12656.7 CBY34438.1 - 0.00047 20.2 0.7 0.00047 20.2 0.7 3.4 2 1 0 2 2 2 1 G-patch domain Macoilin PF09726.9 CBY34438.1 - 0.95 7.9 22.1 1.4 7.3 22.1 1.3 1 0 0 1 1 1 0 Macoilin family Selenoprotein_S PF06936.11 CBY34439.1 - 1.5e-21 77.1 2.3 1.8e-21 76.8 2.3 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) WD40 PF00400.32 CBY34440.1 - 5.5e-24 84.0 5.4 2.1e-09 37.8 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34440.1 - 8.9e-11 41.9 0.0 0.008 16.5 0.0 5.3 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY34440.1 - 0.0061 15.6 0.1 0.048 12.6 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase PF00069.25 CBY34441.1 - 9.5e-55 185.8 0.0 1.3e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34441.1 - 1.3e-31 109.9 0.0 1.7e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34441.1 - 5e-06 26.0 0.0 8.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY34441.1 - 0.0057 16.6 0.0 0.018 15.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY34441.1 - 0.027 13.3 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBY34442.1 - 3.7e-28 98.6 0.0 4.5e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34442.1 - 3.1e-19 69.3 0.0 3.7e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY34442.1 - 0.00022 20.1 0.0 0.00026 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY34442.1 - 0.1 11.9 0.1 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTR2 PF00854.21 CBY34443.1 - 1.7e-75 254.4 8.5 2.3e-75 253.9 8.5 1.2 1 0 0 1 1 1 1 POT family NADH5_C PF06455.11 CBY34443.1 - 0.053 13.1 0.0 0.053 13.1 0.0 2.8 3 1 1 4 4 4 0 NADH dehydrogenase subunit 5 C-terminus DUF998 PF06197.13 CBY34443.1 - 0.43 10.1 9.0 0.96 9.0 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) wnt PF00110.19 CBY34444.1 - 4.8e-33 115.1 21.3 7.2e-32 111.2 21.3 2.0 1 1 0 1 1 1 1 wnt family PKD_channel PF08016.12 CBY34445.1 - 6.3e-136 453.4 7.7 9.9e-136 452.8 7.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY34445.1 - 5.7e-24 84.7 22.0 5.7e-24 84.7 22.0 1.7 2 0 0 2 2 2 1 Ion transport protein Fer4_24 PF18109.1 CBY34445.1 - 1.5e-06 28.3 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain EF-hand_1 PF00036.32 CBY34445.1 - 0.00079 18.8 1.5 0.035 13.7 0.3 3.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY34445.1 - 0.029 14.3 3.0 0.25 11.4 0.1 3.5 3 0 0 3 3 3 0 EF-hand domain Abhydrolase_9_N PF15420.6 CBY34445.1 - 0.14 12.2 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Kelch_4 PF13418.6 CBY34446.1 - 4.9e-12 45.7 1.6 0.069 13.2 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY34446.1 - 1.5e-11 43.7 7.3 0.00092 18.7 0.0 5.9 7 1 0 7 7 7 3 Kelch motif Kelch_3 PF13415.6 CBY34446.1 - 8.5e-09 35.5 0.0 0.13 12.6 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY34446.1 - 4e-07 30.1 4.7 0.059 13.7 0.0 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.6 CBY34446.1 - 2.8e-06 27.2 2.9 1.4 8.9 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY34446.1 - 2.9e-05 23.9 0.4 0.31 11.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif TSNAXIP1_N PF15739.5 CBY34447.1 - 0.031 14.6 6.0 0.027 14.9 3.9 2.0 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus AlkA_N PF06029.11 CBY34447.1 - 0.12 12.7 0.2 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain PikAIV_N PF18605.1 CBY34447.1 - 1.3 8.7 3.9 0.76 9.4 0.9 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF525 PF04379.14 CBY34448.1 - 0.011 15.9 0.2 6.1 7.2 0.0 2.8 3 0 0 3 3 3 0 ApaG domain TMIE PF16038.5 CBY34449.1 - 3.8 7.4 5.2 58 3.6 4.4 3.0 2 0 0 2 2 2 0 TMIE protein Period_C PF12114.8 CBY34450.1 - 0.0079 15.8 0.8 0.0079 15.8 0.8 1.4 2 0 0 2 2 2 1 Period protein 2/3C-terminal region ABC_tran PF00005.27 CBY34451.1 - 4e-49 166.6 0.1 7.4e-24 84.8 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY34451.1 - 3.1e-39 135.1 63.1 3e-23 82.5 25.3 2.3 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY34451.1 - 4.4e-21 76.0 8.1 1.7e-08 34.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY34451.1 - 2.2e-08 33.8 0.5 0.23 10.9 0.0 4.5 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBY34451.1 - 1.8e-07 31.9 1.8 0.017 15.6 0.4 3.0 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 CBY34451.1 - 6.7e-06 26.7 2.1 0.061 14.0 0.1 3.1 3 0 0 3 3 2 2 Domain of unknown function (DUF4162) AAA_29 PF13555.6 CBY34451.1 - 3.2e-05 23.6 0.3 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBY34451.1 - 0.00011 22.1 0.2 0.028 14.3 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CBY34451.1 - 0.00027 20.7 0.0 14 5.3 0.0 4.1 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_15 PF13175.6 CBY34451.1 - 0.00028 20.7 5.3 0.049 13.4 0.0 3.7 5 0 0 5 5 4 2 AAA ATPase domain AAA_24 PF13479.6 CBY34451.1 - 0.00049 19.9 1.2 0.076 12.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CBY34451.1 - 0.0014 18.7 0.6 0.65 10.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 CBY34451.1 - 0.0014 18.3 1.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CBY34451.1 - 0.0022 17.6 0.1 0.32 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 CBY34451.1 - 0.0046 16.8 0.9 0.24 11.2 0.2 2.5 2 0 0 2 2 2 1 MukB N-terminal AAA_16 PF13191.6 CBY34451.1 - 0.015 15.7 0.1 4.2 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBY34451.1 - 0.019 15.3 2.8 3.5 7.9 0.2 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 CBY34451.1 - 0.051 13.2 3.4 2.3 7.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 CBY34451.1 - 0.11 12.5 0.5 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CBY34451.1 - 0.11 11.7 0.3 17 4.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 CBY34451.1 - 0.13 12.6 0.3 8.2 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CBY34451.1 - 1 9.6 3.6 27 5.0 0.7 2.3 2 0 0 2 2 2 0 AAA domain DUF1884 PF08967.10 CBY34451.1 - 9.6 6.5 6.0 12 6.3 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1884) PEN-2 PF10251.9 CBY34454.1 - 1.9e-05 25.0 0.3 2.8e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase SecG PF03840.14 CBY34454.1 - 0.24 11.5 3.3 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Plasmodium_Vir PF05795.11 CBY34455.1 - 3.2 7.1 6.6 4.3 6.7 6.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Endosulfine PF04667.17 CBY34456.1 - 4.3e-11 42.8 0.2 5.2e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DEAD PF00270.29 CBY34458.1 - 1.5e-43 148.6 0.0 3.2e-43 147.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY34458.1 - 4.6e-13 49.5 0.1 1.1e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBY34458.1 - 3.3e-07 30.4 0.0 7.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TRIC PF05197.13 CBY34458.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 TRIC channel CMS1 PF14617.6 CBY34458.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF503 PF04456.12 CBY34458.1 - 0.38 10.6 1.0 4.1 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF503) Geminin PF07412.12 CBY34460.1 - 8.2e-05 22.4 15.9 0.00011 22.0 15.9 1.2 1 0 0 1 1 1 1 Geminin PA28_alpha PF02251.18 CBY34460.1 - 0.16 12.1 4.3 0.36 10.9 0.3 2.8 2 2 0 2 2 2 0 Proteasome activator pa28 alpha subunit LUC7 PF03194.15 CBY34460.1 - 0.24 11.0 12.5 0.28 10.8 12.5 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF962 PF06127.11 CBY34461.1 - 0.093 12.8 5.2 1.2 9.3 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Vps39_1 PF10366.9 CBY34462.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 zinc_ribbon_2 PF13240.6 CBY34465.1 - 0.045 13.5 3.3 0.4 10.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain TSP_1 PF00090.19 CBY34465.1 - 0.17 12.1 19.8 0.19 12.0 5.2 3.0 1 1 2 3 3 3 0 Thrombospondin type 1 domain zf-ribbon_3 PF13248.6 CBY34465.1 - 1.4 8.4 6.4 4.2 6.9 0.1 3.1 4 0 0 4 4 4 0 zinc-ribbon domain Pkinase PF00069.25 CBY34466.1 - 6.7e-59 199.4 0.0 1.3e-58 198.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34466.1 - 4.9e-33 114.5 0.0 1e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IF4E PF01652.18 CBY34467.1 - 3.5e-42 143.9 0.4 4.5e-42 143.5 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF829 PF05705.14 CBY34468.1 - 1.6e-15 57.7 0.0 8.3e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF772 PF05598.11 CBY34470.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase domain (DUF772) DUF2624 PF11116.8 CBY34470.1 - 0.11 13.4 2.7 0.29 12.0 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) Tau95_N PF17682.1 CBY34472.1 - 0.03 14.5 1.3 0.051 13.8 1.3 1.4 1 0 0 1 1 1 0 Tau95 Triple barrel domain Trypan_PARP PF05887.11 CBY34474.1 - 0.21 11.6 9.6 0.39 10.7 9.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aa_trans PF01490.18 CBY34475.1 - 2.7e-61 207.5 18.2 3.7e-61 207.1 18.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3784 PF12650.7 CBY34475.1 - 0.11 12.7 0.1 0.11 12.7 0.1 5.4 5 1 2 7 7 7 0 Domain of unknown function (DUF3784) Kelch_1 PF01344.25 CBY34477.1 - 4.8e-73 240.5 16.6 6.5e-14 51.3 0.6 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 CBY34477.1 - 8e-38 127.5 2.6 2.3e-07 30.8 0.1 6.5 3 2 3 6 6 6 6 Kelch motif BTB PF00651.31 CBY34477.1 - 5.3e-33 113.6 0.0 9.4e-33 112.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY34477.1 - 8.1e-31 106.2 1.3 8.1e-31 106.2 1.3 2.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CBY34477.1 - 1.1e-22 79.8 6.0 0.00057 19.8 0.1 6.2 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY34477.1 - 1.1e-22 79.8 7.5 3.5e-07 30.3 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY34477.1 - 8e-18 63.7 6.5 0.022 14.7 0.0 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 CBY34477.1 - 6.7e-05 22.8 8.2 0.51 10.4 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 CBY34477.1 - 0.00041 19.6 0.8 0.33 10.1 0.2 2.9 2 1 1 3 3 3 3 Glyoxal oxidase N-terminus DUF3342 PF11822.8 CBY34477.1 - 0.0021 18.2 0.2 0.018 15.3 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 CBY34477.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DAO_C PF16901.5 CBY34477.1 - 0.14 12.0 0.0 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase PQQ_3 PF13570.6 CBY34477.1 - 4.4 7.9 12.4 7.9 7.1 0.2 4.1 4 0 0 4 4 4 0 PQQ-like domain LRR_9 PF14580.6 CBY34478.1 - 1.9e-85 284.7 3.1 2.5e-85 284.3 3.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY34478.1 - 5.9e-13 48.8 8.8 5.5e-09 36.2 0.9 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY34478.1 - 3.3e-11 42.8 3.3 3.4e-11 42.7 0.2 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 CBY34478.1 - 0.17 12.5 5.6 26 5.9 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat GARS_A PF01071.19 CBY34479.1 - 0.053 13.3 0.1 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ion_trans PF00520.31 CBY34480.1 - 2.2e-27 95.9 16.3 2.9e-27 95.5 16.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY34480.1 - 1.1e-09 38.1 2.4 1.1e-09 38.1 2.4 2.4 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 CBY34480.1 - 1.3e-08 34.7 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Streptin-Immun PF11083.8 CBY34482.1 - 0.27 11.6 9.7 0.13 12.7 1.8 3.9 3 1 1 4 4 4 0 Lantibiotic streptin immunity protein p25-alpha PF05517.12 CBY34482.1 - 0.51 10.5 0.0 0.51 10.5 0.0 2.5 2 1 0 2 2 2 0 p25-alpha zf-MYND PF01753.18 CBY34482.1 - 0.78 9.9 4.8 1.5 8.9 4.8 1.5 1 0 0 1 1 1 0 MYND finger PDCD2_C PF04194.13 CBY34482.1 - 8.6 6.4 9.9 0.17 11.9 1.9 2.3 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain SNF2_N PF00176.23 CBY34484.1 - 6.6e-49 166.5 0.2 1.2e-48 165.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY34484.1 - 6e-13 49.1 0.0 1.8e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY34484.1 - 6.3e-08 32.8 3.1 1.9e-07 31.3 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-4CXXC_R1 PF10497.9 CBY34484.1 - 0.0041 17.3 1.9 0.0091 16.2 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD PF00628.29 CBY34484.1 - 0.02 14.8 4.4 0.051 13.5 4.4 1.7 1 0 0 1 1 1 0 PHD-finger RR_TM4-6 PF06459.12 CBY34484.1 - 2.1 8.1 9.1 3.7 7.3 4.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Gla PF00594.20 CBY34485.1 - 1.2e-11 44.6 1.2 1.9e-11 44.0 1.2 1.4 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain ANAPC4_WD40 PF12894.7 CBY34486.1 - 1.1e-05 25.6 0.2 0.15 12.4 0.1 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY34486.1 - 0.0014 19.4 13.3 0.71 10.8 1.4 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ETF_QO PF05187.13 CBY34486.1 - 0.1 12.7 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Hydin_ADK PF17213.3 CBY34486.1 - 7.9 6.7 6.2 14 5.9 6.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RecR PF02132.15 CBY34487.1 - 2.6 7.7 6.9 2.6 7.7 0.3 2.4 2 0 0 2 2 2 0 RecR protein wnt PF00110.19 CBY34488.1 - 4.7e-51 174.2 25.6 5.9e-51 173.9 25.6 1.1 1 0 0 1 1 1 1 wnt family SSF PF00474.17 CBY34489.1 - 1.1e-35 123.4 29.2 1.4e-35 123.0 29.2 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family EGF PF00008.27 CBY34490.1 - 9.1e-87 284.8 429.3 1.9e-07 31.2 11.9 29.3 29 2 2 31 31 31 25 EGF-like domain hEGF PF12661.7 CBY34490.1 - 2.3e-50 167.6 326.0 0.00059 20.4 10.0 29.8 28 0 0 28 28 28 25 Human growth factor-like EGF EGF_2 PF07974.13 CBY34490.1 - 2.7e-22 78.8 436.5 0.00022 21.5 3.5 27.0 26 1 1 27 27 27 19 EGF-like domain EGF_3 PF12947.7 CBY34490.1 - 2.9e-06 27.4 373.2 0.0048 17.1 4.9 27.1 26 3 2 28 28 28 18 EGF domain EGF_CA PF07645.15 CBY34490.1 - 0.00014 22.0 53.5 0.0016 18.6 12.0 26.2 6 4 22 28 28 28 8 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY34490.1 - 0.0065 16.8 3.9 0.0065 16.8 3.9 27.6 15 8 12 27 27 27 11 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY34490.1 - 0.013 15.8 9.0 0.013 15.8 9.0 25.9 11 10 13 24 24 24 0 Coagulation Factor Xa inhibitory site Claudin_2 PF13903.6 CBY34491.1 - 0.083 12.6 6.1 0.13 12.0 6.1 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 CBY34491.1 - 0.29 11.0 6.7 0.94 9.4 6.7 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Lectin_C PF00059.21 CBY34492.1 - 6.2e-15 55.9 22.5 4.6e-05 24.1 1.4 4.6 4 0 0 4 4 4 4 Lectin C-type domain TMC PF07810.13 CBY34493.1 - 2.7e-32 111.7 0.8 2.7e-32 111.7 0.8 3.6 6 0 0 6 6 6 1 TMC domain Shisa PF13908.6 CBY34493.1 - 0.31 11.3 0.3 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3382 PF11862.8 CBY34493.1 - 1.1 9.6 5.4 0.59 10.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) Tfb2 PF03849.14 CBY34494.1 - 0.082 11.9 1.1 0.14 11.1 1.1 1.3 1 0 0 1 1 1 0 Transcription factor Tfb2 YrzO PF14142.6 CBY34494.1 - 0.21 11.5 1.2 0.57 10.1 1.2 1.7 1 0 0 1 1 1 0 YrzO-like protein TFIIA PF03153.13 CBY34494.1 - 4.5 7.2 17.3 5.8 6.8 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 CBY34495.1 - 1.4e-06 27.5 23.2 7.3e-06 25.1 23.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Thioredoxin PF00085.20 CBY34496.1 - 2.4e-24 85.3 0.0 5.6e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CBY34496.1 - 6e-10 39.3 0.0 6.3e-05 23.0 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY34496.1 - 0.0056 17.1 0.0 0.077 13.5 0.0 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Nop53 PF07767.11 CBY34496.1 - 0.5 9.7 4.6 0.71 9.2 4.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CN_hydrolase PF00795.22 CBY34497.1 - 1.3e-61 208.2 0.0 1.5e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zinc_ribbon_9 PF14369.6 CBY34499.1 - 0.012 15.9 0.4 0.015 15.5 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon MPS-4 PF17523.2 CBY34500.1 - 0.079 13.1 1.8 0.14 12.3 1.8 1.5 1 1 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 PARG_cat PF05028.14 CBY34501.1 - 5.1e-48 164.1 0.9 1.4e-38 133.0 0.1 2.2 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) DUF2465 PF10239.9 CBY34501.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) BESS PF02944.20 CBY34501.1 - 0.16 11.8 0.4 7.5 6.5 0.1 3.0 3 0 0 3 3 3 0 BESS motif PARG_cat PF05028.14 CBY34502.1 - 1.7e-108 362.9 0.0 2.6e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Kelch_5 PF13854.6 CBY34503.1 - 0.00054 19.9 1.6 0.013 15.5 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY34503.1 - 0.004 17.1 1.5 1.3 9.1 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY34503.1 - 0.0058 16.9 2.2 0.43 10.9 0.0 3.4 2 1 0 3 3 3 1 Kelch motif Pkinase PF00069.25 CBY34505.1 - 3.3e-24 85.7 0.6 2.9e-14 53.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34505.1 - 2.3e-14 53.3 0.2 4.4e-07 29.4 0.0 3.0 2 2 1 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY34505.1 - 2.7e-12 46.2 0.1 6.9e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CBY34505.1 - 4e-10 40.0 0.0 0.00046 20.2 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBY34505.1 - 0.00036 19.6 0.8 0.59 9.0 0.1 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Ribosomal_L21e PF01157.18 CBY34505.1 - 0.0017 18.2 1.6 1.6 8.6 0.1 2.6 2 0 0 2 2 2 2 Ribosomal protein L21e HECA PF15353.6 CBY34505.1 - 0.023 14.9 0.9 8.6 6.7 0.2 2.5 2 0 0 2 2 2 0 Headcase protein family homologue Cdc6_C PF09079.11 CBY34505.1 - 0.099 12.6 0.1 25 4.9 0.0 2.6 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain PDZ_2 PF13180.6 CBY34506.1 - 2.9e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY34506.1 - 8.1e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY34506.1 - 0.00053 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Myb_DNA-binding PF00249.31 CBY34506.1 - 0.00099 19.3 0.8 0.0022 18.2 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 CBY34506.1 - 0.0032 17.5 0.3 0.0032 17.5 0.3 2.8 2 0 0 2 2 2 1 SLIDE Myb_DNA-bind_6 PF13921.6 CBY34506.1 - 0.012 15.9 0.1 0.056 13.7 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2259 PF10016.9 CBY34506.1 - 0.11 12.4 1.8 0.36 10.7 1.8 1.8 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) DUF3394 PF11874.8 CBY34506.1 - 0.16 11.6 1.4 1.4 8.6 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3394) NFACT-R_1 PF05670.13 CBY34507.1 - 1.3e-41 141.7 0.0 2.1e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF1682 PF07946.14 CBY34507.1 - 0.049 12.8 7.9 0.065 12.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GDC-P PF02347.16 CBY34508.1 - 9e-08 31.4 0.1 1.4e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CBY34508.1 - 0.00018 20.6 0.1 0.00023 20.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 CBY34509.1 - 1.1e-167 558.3 0.0 1.4e-166 554.6 0.1 1.9 2 0 0 2 2 2 2 Glycine cleavage system P-protein Cadherin PF00028.17 CBY34510.1 - 2.4e-64 213.8 1.2 6.2e-16 58.6 0.0 6.4 6 0 0 6 6 6 5 Cadherin domain Cadherin_2 PF08266.12 CBY34510.1 - 1e-08 34.9 0.8 2.4e-05 24.1 0.0 4.4 5 0 0 5 5 5 1 Cadherin-like Cadherin_4 PF17803.1 CBY34510.1 - 0.00081 20.0 13.0 0.46 11.1 0.6 5.5 5 1 0 5 5 5 2 Bacterial cadherin-like domain Cadherin_3 PF16184.5 CBY34510.1 - 0.00095 19.1 5.4 0.48 10.5 0.1 4.8 4 1 1 5 5 5 2 Cadherin-like Orf78 PF06024.12 CBY34510.1 - 0.002 18.4 0.3 0.0055 17.0 0.0 1.8 2 0 0 2 2 2 1 Orf78 (ac78) DUF1180 PF06679.12 CBY34510.1 - 0.035 14.5 0.3 0.035 14.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 CBY34510.1 - 0.088 13.7 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4212 PF13937.6 CBY34510.1 - 0.094 13.1 0.2 0.18 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Ribonuc_P_40 PF08584.11 CBY34510.1 - 0.16 11.2 0.7 0.29 10.4 0.7 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Cadherin-like PF12733.7 CBY34510.1 - 1.2 9.7 9.6 0.72 10.4 0.4 3.7 4 1 1 5 5 5 0 Cadherin-like beta sandwich domain Galactosyl_T PF01762.21 CBY34511.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase G10 PF01125.17 CBY34513.1 - 8.8e-67 223.4 8.3 9.7e-67 223.3 8.3 1.0 1 0 0 1 1 1 1 G10 protein LRR_8 PF13855.6 CBY34514.1 - 5.6e-18 64.5 11.9 2.5e-10 39.9 3.5 4.4 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBY34514.1 - 8.1e-16 57.9 25.5 4.8e-07 30.0 0.3 5.5 2 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY34514.1 - 0.0026 17.3 6.8 0.23 10.9 0.6 3.7 1 1 3 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 CBY34514.1 - 0.048 14.2 18.4 20 6.3 0.1 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat UPF0029 PF01205.19 CBY34515.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TF_AP-2 PF03299.14 CBY34516.1 - 0.069 13.1 2.5 2.2 8.2 1.2 2.3 2 0 0 2 2 2 0 Transcription factor AP-2 zf-AN1 PF01428.16 CBY34516.1 - 0.4 10.9 2.9 0.89 9.8 2.9 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger ASC PF00858.24 CBY34518.1 - 1e-54 186.2 13.4 1.2e-54 185.9 13.4 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel TPT PF03151.16 CBY34519.1 - 2e-24 86.4 19.0 2.5e-24 86.1 19.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY34519.1 - 3.4e-10 40.2 7.0 3.4e-10 40.2 7.0 2.2 2 0 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.19 CBY34519.1 - 0.17 12.6 0.2 0.17 12.6 0.2 3.1 2 1 1 3 3 3 0 Small Multidrug Resistance protein DUF1674 PF07896.12 CBY34520.1 - 0.96 10.0 3.0 0.79 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) PfkB PF00294.24 CBY34521.1 - 4.1e-40 138.0 0.1 5.3e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pkinase PF00069.25 CBY34523.1 - 6.4e-67 225.7 0.0 8.2e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34523.1 - 2e-40 138.7 0.0 2.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34523.1 - 6.2e-09 35.6 0.2 7.3e-06 25.5 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBY34523.1 - 0.0022 17.4 0.5 0.0034 16.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY34523.1 - 0.0087 16.0 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY34523.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY34523.1 - 0.039 13.5 0.1 0.039 13.5 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SCAB-PH PF17684.1 CBY34523.1 - 0.092 13.0 0.1 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 PH domain of plant-specific actin-binding protein IL17R_D_N PF16742.5 CBY34523.1 - 0.092 12.8 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 N-terminus of interleukin 17 receptor D PP2C PF00481.21 CBY34526.1 - 1.2e-30 107.0 0.0 4.7e-30 105.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY34526.1 - 4e-10 39.7 0.0 7.5e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3670 PF12419.8 CBY34526.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein RSF PF14876.6 CBY34527.1 - 0.00095 18.2 0.1 0.0014 17.7 0.1 1.1 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator Glyco_hydro_1 PF00232.18 CBY34528.1 - 0 1179.4 16.2 7.5e-129 430.1 2.8 3.8 4 1 0 4 4 4 3 Glycosyl hydrolase family 1 zf_CCCH_5 PF18384.1 CBY34530.1 - 1.3e-21 76.4 22.1 1.7e-21 76.1 13.4 3.4 2 0 0 2 2 2 1 Unkempt Zinc finger domain 1 (Znf1) zf-CCCH PF00642.24 CBY34530.1 - 5.1e-06 26.2 3.1 5.1e-06 26.2 3.1 5.4 6 0 0 6 6 6 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY34530.1 - 0.034 14.2 0.6 0.034 14.2 0.6 5.1 5 0 0 5 5 5 0 Zinc finger domain DUF1664 PF07889.12 CBY34531.1 - 0.024 14.6 3.7 0.026 14.6 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) P4Ha_N PF08336.11 CBY34531.1 - 0.039 14.0 1.3 0.047 13.7 1.0 1.4 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FlaC_arch PF05377.11 CBY34531.1 - 0.061 13.7 3.6 0.093 13.1 1.2 2.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-18_N PF10496.9 CBY34531.1 - 0.069 13.4 3.2 0.31 11.3 0.6 2.0 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Fib_alpha PF08702.10 CBY34531.1 - 0.11 12.7 2.4 0.12 12.6 1.2 1.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Synapsin_C PF02750.14 CBY34534.1 - 8.4e-33 113.6 0.0 3.7e-32 111.5 0.0 2.0 1 1 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 CBY34534.1 - 8e-19 67.8 0.1 2.6e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Synapsin, N-terminal domain PAN_1 PF00024.26 CBY34535.1 - 4.3e-08 33.0 4.6 0.0016 18.4 0.7 2.2 1 1 1 2 2 2 2 PAN domain PAN_4 PF14295.6 CBY34535.1 - 4.6e-05 23.2 12.7 0.0022 17.8 1.0 2.8 3 0 0 3 3 3 2 PAN domain zf-C2H2_2 PF12756.7 CBY34537.1 - 8.8e-26 90.2 8.3 5.3e-20 71.6 0.0 3.1 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY34537.1 - 3.8e-07 30.2 12.8 2.9e-06 27.4 3.1 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY34537.1 - 0.0015 19.2 9.2 0.024 15.5 0.5 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger DUF629 PF04780.12 CBY34537.1 - 0.0028 16.3 7.7 0.024 13.2 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf-met PF12874.7 CBY34537.1 - 0.021 15.2 3.1 0.021 15.2 3.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY34537.1 - 5.8 7.6 9.1 2 9.0 0.7 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF2856 PF11043.8 CBY34538.1 - 0.12 12.5 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) UPF0182 PF03699.13 CBY34539.1 - 0.76 7.8 5.0 1.1 7.3 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sulfatase PF00884.23 CBY34540.1 - 9.5e-69 232.1 0.0 1.3e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY34540.1 - 1.4e-28 100.1 0.0 2.1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase CAAD PF14159.6 CBY34540.1 - 0.027 14.3 0.2 0.053 13.4 0.2 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1394 PF07159.12 CBY34541.1 - 6.1e-111 370.5 7.5 7e-111 370.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ADIP PF11559.8 CBY34541.1 - 0.14 12.2 4.9 0.94 9.6 0.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GCP_C_terminal PF04130.13 CBY34542.1 - 1e-11 44.9 1.1 1.2e-11 44.7 1.1 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 CBY34543.1 - 1.5e-299 995.0 9.8 1.7e-299 994.8 9.8 1.0 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 GCP_N_terminal PF17681.1 CBY34543.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal DUF2151 PF10221.9 CBY34543.1 - 0.1 11.2 2.4 0.16 10.6 2.4 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Rad21_Rec8 PF04824.16 CBY34544.1 - 2.1e-15 55.7 0.0 5e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein VLPT PF07122.11 CBY34545.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) PEN-2 PF10251.9 CBY34546.1 - 0.025 15.0 2.0 0.029 14.8 2.0 1.1 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase AHSP PF09236.10 CBY34547.1 - 0.11 13.0 0.2 0.28 11.6 0.2 1.6 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF2666 PF10869.8 CBY34547.1 - 0.26 11.5 3.6 9.9 6.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Sec3_C_2 PF15278.6 CBY34547.1 - 0.56 10.6 3.2 2.1 8.8 0.0 3.4 5 0 0 5 5 5 0 Sec3 exocyst complex subunit CBFD_NFYB_HMF PF00808.23 CBY34551.1 - 1.6e-14 54.0 0.7 2.3e-14 53.4 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY34551.1 - 0.00012 22.5 0.2 0.00012 22.5 0.2 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CBY34551.1 - 0.03 14.4 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.15 CBY34552.1 - 1.9e-54 184.1 0.1 3.3e-54 183.2 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.24 CBY34552.1 - 1.6e-08 34.8 0.1 3.5e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY34552.1 - 9e-07 28.6 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY34552.1 - 0.015 15.6 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Thioredoxin PF00085.20 CBY34553.1 - 5.2e-64 212.7 0.1 3.2e-31 107.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY34553.1 - 8.1e-40 136.7 0.0 3.3e-35 121.7 0.1 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY34553.1 - 2.3e-09 37.7 0.1 0.0055 17.1 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY34553.1 - 9.7e-09 35.3 0.0 0.0027 17.8 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY34553.1 - 2.2e-07 30.8 1.1 0.032 14.1 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY34553.1 - 7.9e-07 29.3 0.0 0.054 13.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY34553.1 - 1e-06 28.4 0.0 0.065 12.6 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CBY34553.1 - 0.00034 20.4 1.4 1.5 8.5 0.0 3.8 4 0 0 4 4 4 1 Redoxin Thioredoxin_4 PF13462.6 CBY34553.1 - 0.0078 16.4 0.1 0.63 10.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 CBY34553.1 - 0.091 12.4 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin HyaE PF07449.11 CBY34553.1 - 0.11 12.5 0.4 23 5.0 0.0 3.7 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE TMEM132D_C PF15706.5 CBY34554.1 - 0.096 12.5 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TNFR_16_TM PF18422.1 CBY34555.1 - 0.12 12.3 0.8 0.17 11.8 0.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain WD40 PF00400.32 CBY34556.1 - 1.1e-36 124.1 21.3 2.4e-06 28.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34556.1 - 3e-11 43.5 0.1 0.0023 18.2 0.1 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3668 PF12416.8 CBY34557.1 - 5.3e-19 68.9 2.3 2.1e-17 63.7 0.0 3.9 3 2 0 3 3 3 1 Cep120 protein DUF4497 PF14924.6 CBY34557.1 - 0.0058 17.1 0.9 0.12 12.8 0.0 3.5 5 0 0 5 5 5 1 Protein of unknown function (DUF4497) C2 PF00168.30 CBY34557.1 - 0.035 14.4 0.0 15 5.9 0.0 3.0 2 1 0 2 2 2 0 C2 domain NT-C2 PF10358.9 CBY34557.1 - 0.058 13.1 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins SAM_Exu PF18609.1 CBY34557.1 - 8.6 6.5 9.1 0.45 10.6 0.6 3.2 3 0 0 3 3 3 0 Exuperantia SAM-like domain DUF4537 PF15057.6 CBY34558.1 - 2.7e-47 159.7 1.1 1.5e-24 86.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY34558.1 - 4.5e-05 23.2 0.0 1.5 8.8 0.0 4.2 4 0 0 4 4 4 2 DNA repair protein Crb2 Tudor domain DUF4819 PF16090.5 CBY34558.1 - 0.0069 16.4 0.2 13 6.0 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4819) Tudor_2 PF18104.1 CBY34558.1 - 0.041 13.6 0.0 0.9 9.3 0.0 3.3 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Chordopox_A13L PF05961.11 CBY34558.1 - 0.18 12.1 0.2 0.4 11.0 0.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DNA_pol_A_exo1 PF01612.20 CBY34559.1 - 1.3e-41 142.2 0.2 2.4e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CBY34559.1 - 1e-11 45.3 0.0 2.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 PMC2NT (NUC016) domain DUF3638 PF12340.8 CBY34559.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Rgp1 PF08737.10 CBY34561.1 - 0.0014 17.9 0.6 0.0019 17.4 0.3 1.4 2 0 0 2 2 2 1 Rgp1 Rgp1 PF08737.10 CBY34562.1 - 7.4e-19 68.2 0.4 3.3e-15 56.2 0.1 2.5 2 1 1 3 3 3 2 Rgp1 Arrestin_N PF00339.29 CBY34562.1 - 0.001 19.1 0.5 0.0036 17.4 0.5 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain adh_short PF00106.25 CBY34563.1 - 9e-46 155.8 0.5 1.2e-45 155.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY34563.1 - 1.1e-42 146.2 0.6 1.9e-42 145.5 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY34563.1 - 8.4e-09 35.6 2.7 1.6e-07 31.4 2.2 2.3 1 1 0 1 1 1 1 KR domain PALP PF00291.25 CBY34563.1 - 0.0015 18.0 0.2 0.0027 17.2 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 CBY34563.1 - 0.0065 16.0 0.1 0.014 14.9 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family MAD PF05557.13 CBY34564.1 - 2.3e-08 32.9 15.9 2.3e-08 32.9 15.9 2.7 1 1 1 2 2 2 1 Mitotic checkpoint protein GAS PF13851.6 CBY34564.1 - 0.0095 15.3 7.9 0.0095 15.3 7.9 5.1 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding FBA PF04300.13 CBY34564.1 - 0.0096 15.6 2.3 0.013 15.2 1.2 1.9 2 0 0 2 2 2 1 F-box associated region Viral_env_E26 PF11050.8 CBY34564.1 - 0.017 14.5 6.5 0.031 13.7 2.4 2.5 1 1 1 2 2 2 0 Virus envelope protein E26 COMM_domain PF07258.14 CBY34564.1 - 0.023 14.8 3.6 0.03 14.4 1.4 2.4 2 0 0 2 2 2 0 COMM domain CCDC92 PF14916.6 CBY34564.1 - 0.026 14.3 0.3 0.026 14.3 0.3 3.7 4 0 0 4 4 4 0 Coiled-coil domain of unknown function DUF2399 PF09664.10 CBY34564.1 - 0.73 9.7 5.5 1.3 8.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2399) TolA_bind_tri PF16331.5 CBY34564.1 - 1.4 9.0 28.7 4.5 7.4 1.8 6.3 3 2 1 5 5 5 0 TolA binding protein trimerisation Golgin_A5 PF09787.9 CBY34564.1 - 2.6 7.4 57.8 0.67 9.4 8.5 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 Spc7 PF08317.11 CBY34564.1 - 3.1 6.6 57.3 0.13 11.1 4.9 4.3 2 1 2 4 4 4 0 Spc7 kinetochore protein Astacin PF01400.24 CBY34567.1 - 7.6e-28 97.4 0.1 1.4e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY34567.1 - 0.0015 18.7 4.4 0.0015 18.7 4.4 2.5 2 0 0 2 2 2 1 Low-density lipoprotein receptor domain class A Mucin PF01456.17 CBY34567.1 - 0.12 12.4 28.3 0.22 11.5 28.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF45 PF01863.17 CBY34567.1 - 0.32 11.0 1.2 0.52 10.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 PRKCSH-like PF12999.7 CBY34567.1 - 1.3 8.8 6.0 4.6 7.0 6.0 2.0 1 1 0 1 1 1 0 Glucosidase II beta subunit-like PknH_C PF14032.6 CBY34567.1 - 2.8 7.8 11.3 6 6.7 11.3 1.5 1 0 0 1 1 1 0 PknH-like extracellular domain FSA_C PF10479.9 CBY34567.1 - 2.9 5.9 13.3 4.1 5.4 13.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus BSP_II PF05432.11 CBY34567.1 - 6.2 6.4 7.8 9.5 5.8 7.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PLAC8 PF04749.17 CBY34568.1 - 1.3e-13 51.7 20.3 1.6e-13 51.5 20.3 1.1 1 0 0 1 1 1 1 PLAC8 family zf-C2H2_4 PF13894.6 CBY34569.1 - 0.00052 20.6 8.7 0.18 12.7 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY34569.1 - 0.0013 19.1 7.8 0.25 11.9 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY34569.1 - 0.0052 17.2 9.6 0.15 12.6 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY34569.1 - 0.0087 16.4 0.9 0.0087 16.4 0.9 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ribosomal_L37ae PF01780.19 CBY34569.1 - 0.013 15.6 1.8 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF2318 PF10080.9 CBY34569.1 - 0.034 14.2 0.2 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zinc_ribbon_4 PF13717.6 CBY34569.1 - 0.052 13.5 1.8 0.14 12.1 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.8 CBY34569.1 - 0.061 13.6 0.9 0.061 13.6 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY34569.1 - 0.089 13.1 4.5 1.1 9.6 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CBY34569.1 - 0.15 12.1 2.1 0.72 9.9 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger Na_Pi_cotrans PF02690.15 CBY34570.1 - 2.3e-32 112.0 27.2 2.8e-19 69.6 8.5 2.8 3 0 0 3 3 3 2 Na+/Pi-cotransporter P4Ha_N PF08336.11 CBY34571.1 - 5.9e-16 58.7 0.6 1.2e-15 57.7 0.1 1.8 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY34571.1 - 1.4e-13 51.5 0.2 1e-12 48.7 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBY34571.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.6 CBY34571.1 - 0.18 12.5 2.0 0.55 11.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Tegument_dsDNA PF12818.7 CBY34572.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein TPR_12 PF13424.6 CBY34573.1 - 9.1e-17 61.1 9.6 3.1e-06 27.4 0.7 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY34573.1 - 5e-11 41.8 13.6 0.15 12.2 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY34573.1 - 1.1e-09 38.3 7.3 0.00019 21.6 0.3 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBY34573.1 - 7.9e-08 31.8 15.1 0.0051 16.6 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY34573.1 - 1.8e-06 27.5 1.5 0.068 12.9 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 CBY34573.1 - 6.2e-06 26.6 9.4 0.094 13.2 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY34573.1 - 8.7e-06 26.3 5.6 0.0057 17.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 CBY34573.1 - 4.6e-05 23.2 8.2 0.00028 20.6 3.6 2.9 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 CBY34573.1 - 0.00013 21.7 9.6 0.28 11.3 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY34573.1 - 0.00024 21.6 9.1 11 7.2 0.1 6.3 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY34573.1 - 0.00061 19.8 13.2 1.9 8.9 0.2 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY34573.1 - 0.0046 16.4 2.9 0.022 14.1 3.0 1.8 2 0 0 2 2 2 1 MalT-like TPR region ANTH PF07651.16 CBY34573.1 - 0.0069 15.4 0.3 0.011 14.8 0.3 1.4 1 0 0 1 1 1 1 ANTH domain TPR_17 PF13431.6 CBY34573.1 - 0.024 15.0 4.5 3.2 8.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBY34573.1 - 0.033 14.8 2.5 19 6.3 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBY34573.1 - 0.064 13.0 6.9 1.4 8.6 4.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CBY34573.1 - 0.16 11.9 13.7 0.22 11.4 0.5 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY34573.1 - 0.92 10.3 9.2 43 5.0 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Reprolysin_2 PF13574.6 CBY34574.1 - 3.3e-29 102.2 0.0 8e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY34574.1 - 3.1e-24 86.2 0.0 6.6e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY34574.1 - 2.1e-17 63.8 0.0 3.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CBY34574.1 - 6.3e-13 49.3 30.4 6.3e-13 49.3 30.4 3.1 2 1 0 2 2 2 1 Disintegrin Reprolysin_4 PF13583.6 CBY34574.1 - 3.9e-10 39.7 0.0 9.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 CBY34574.1 - 3.3e-05 24.1 0.1 7.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.9 CBY34574.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 UPF0370 PF13980.6 CBY34574.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) RIO1 PF01163.22 CBY34575.1 - 7.3e-68 227.9 0.0 7.3e-68 227.9 0.0 2.5 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CBY34575.1 - 0.022 14.7 0.3 0.15 12.0 0.3 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4498 PF14926.6 CBY34576.1 - 1e-60 205.1 2.9 1.2e-60 204.9 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) GEP5 PF17053.5 CBY34576.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 LRR_8 PF13855.6 CBY34579.1 - 4.9e-09 35.8 7.9 1.6e-05 24.6 2.4 2.0 1 1 1 2 2 2 2 Leucine rich repeat RsmF_methylt_CI PF17126.5 CBY34579.1 - 0.026 14.6 0.0 15 5.7 0.0 3.8 3 1 1 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LRR_4 PF12799.7 CBY34579.1 - 0.038 14.4 7.6 2.4 8.7 2.2 2.5 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) FAD-SLDH PF12318.8 CBY34580.1 - 0.037 14.1 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase COG5 PF10392.9 CBY34580.1 - 0.19 11.9 3.0 0.26 11.5 3.0 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 MyTH4 PF00784.17 CBY34581.1 - 3.1e-09 37.3 0.1 8.3e-09 35.9 0.0 1.8 2 1 0 2 2 2 1 MyTH4 domain FXa_inhibition PF14670.6 CBY34583.1 - 0.087 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site FlxA PF14282.6 CBY34587.1 - 1.5 8.8 14.7 3.8 7.6 14.8 1.6 1 1 0 1 1 1 0 FlxA-like protein ShK PF01549.24 CBY34588.1 - 1.6e-09 38.1 29.3 2.6e-05 24.7 8.9 2.6 2 0 0 2 2 2 2 ShK domain-like ABC_membrane PF00664.23 CBY34589.1 - 4.1e-43 148.0 4.5 4.1e-43 148.0 4.5 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY34589.1 - 1.2e-31 110.1 0.0 1.9e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CBY34589.1 - 0.00028 21.2 0.1 0.0012 19.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY34589.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 CBY34589.1 - 0.0014 18.2 0.0 0.027 13.9 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CBY34589.1 - 0.0046 15.8 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY34589.1 - 0.0049 17.3 0.0 0.0092 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CBY34589.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBY34589.1 - 0.093 12.4 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CBY34589.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 CBY34589.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 CBY34589.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CBY34589.1 - 0.14 12.1 0.0 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CBY34589.1 - 0.15 12.4 0.4 1.2 9.4 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CBY34589.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CBY34590.1 - 3.7e-34 118.2 0.0 6.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY34590.1 - 7.9e-09 35.3 0.0 6.4e-07 29.0 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY34590.1 - 0.00013 22.3 0.1 0.0015 18.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBY34590.1 - 0.0027 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 CBY34590.1 - 0.0079 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class ABC_membrane PF00664.23 CBY34590.1 - 0.01 15.5 0.5 0.014 15.1 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_15 PF13175.6 CBY34590.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 CBY34590.1 - 0.013 15.7 0.2 0.23 11.7 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBY34590.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBY34590.1 - 0.038 13.3 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBY34590.1 - 0.04 14.3 0.6 0.56 10.6 0.5 2.6 1 1 1 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 CBY34590.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 CBY34590.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Trypan_PARP PF05887.11 CBY34592.1 - 0.00014 21.8 16.2 0.00025 21.0 16.2 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 CBY34592.1 - 0.0011 19.5 19.3 0.0021 18.6 19.3 1.4 1 0 0 1 1 1 1 TonB polyproline region DUF3165 PF11364.8 CBY34592.1 - 0.069 13.5 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) SPESP1 PF15754.5 CBY34592.1 - 4.8 6.3 13.6 20 4.3 13.6 1.8 1 1 0 1 1 1 0 Sperm equatorial segment protein 1 Phospholip_A2_1 PF00068.19 CBY34593.1 - 0.0011 19.5 6.9 0.0011 19.5 6.9 1.8 2 1 0 2 2 2 1 Phospholipase A2 Sulfate_transp PF00916.20 CBY34594.1 - 9.4e-95 317.5 16.7 1.9e-94 316.6 16.7 1.4 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY34594.1 - 6e-08 32.3 1.6 7.6e-08 32.0 0.3 1.7 2 0 0 2 2 2 1 STAS domain GDP_Man_Dehyd PF16363.5 CBY34597.1 - 7.9e-55 186.6 0.0 2.2e-54 185.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY34597.1 - 2.2e-49 168.1 0.0 2.8e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CBY34597.1 - 6.6e-08 32.0 0.0 0.0011 18.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CBY34597.1 - 1e-07 31.3 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CBY34597.1 - 2.8e-06 26.7 0.0 5.6e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBY34597.1 - 1.3e-05 24.5 0.1 0.0011 18.2 0.1 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY34597.1 - 0.061 13.2 0.0 0.47 10.3 0.0 2.3 3 0 0 3 3 3 0 KR domain adh_short PF00106.25 CBY34597.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase LEM PF03020.15 CBY34599.1 - 2.2e-25 87.9 0.5 3.2e-12 45.8 0.1 3.1 3 0 0 3 3 3 2 LEM domain MSC PF09402.10 CBY34599.1 - 5.2e-11 42.6 0.1 8e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain RecO_N_2 PF13114.6 CBY34599.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 RecO N terminal Xpo1 PF08389.12 CBY34601.1 - 4.3e-18 65.8 6.5 2.6e-17 63.3 0.1 4.7 3 3 1 4 4 4 1 Exportin 1-like protein Importin_rep PF18773.1 CBY34601.1 - 3.9e-16 58.5 0.0 9.3e-16 57.3 0.0 1.7 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 CBY34601.1 - 1.7e-06 28.0 0.0 7.8e-06 25.8 0.0 2.3 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 CBY34601.1 - 0.00094 19.1 1.7 0.0064 16.4 0.3 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain EH_Signature PF15611.6 CBY34601.1 - 0.057 12.8 0.3 0.17 11.3 0.3 1.8 1 0 0 1 1 1 0 EH_Signature domain FAM193_C PF15914.5 CBY34602.1 - 5.6e-05 22.8 0.2 5.6e-05 22.8 0.2 2.7 3 0 0 3 3 3 1 FAM193 family C-terminal PNISR PF15996.5 CBY34603.1 - 3.9e-06 27.3 4.4 3.9e-06 27.3 4.4 2.6 1 1 0 2 2 2 1 Arginine/serine-rich protein PNISR BMC PF00936.19 CBY34604.1 - 0.014 15.4 0.1 0.041 13.9 0.1 1.8 1 0 0 1 1 1 0 BMC domain PIEZO PF15917.5 CBY34605.1 - 2.1 7.8 5.8 0.31 10.5 1.0 1.9 2 0 0 2 2 2 0 Piezo Ank_2 PF12796.7 CBY34606.1 - 0.0063 17.1 0.0 0.032 14.8 0.0 1.9 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY34606.1 - 0.081 13.4 0.2 22 5.7 0.1 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 CBY34606.1 - 0.17 12.5 0.0 1.2 9.8 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Connexin PF00029.19 CBY34607.1 - 2e-52 178.3 17.9 6.3e-30 104.7 1.6 2.7 2 1 1 3 3 3 2 Connexin DUF4611 PF15387.6 CBY34607.1 - 0.012 15.8 2.1 0.027 14.7 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HLH PF00010.26 CBY34608.1 - 9.9e-07 28.6 2.2 1.5e-06 28.1 2.2 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 CBY34609.1 - 1.1e-22 80.5 24.2 1.4e-22 80.1 24.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Homeodomain PF00046.29 CBY34611.1 - 1.8e-19 69.3 1.1 1.8e-19 69.3 1.1 1.6 2 0 0 2 2 2 1 Homeodomain LIM PF00412.22 CBY34611.1 - 3.5e-09 36.7 30.2 4.3e-06 26.8 17.9 2.4 2 0 0 2 2 2 2 LIM domain Homeobox_KN PF05920.11 CBY34611.1 - 9.8e-06 25.4 0.1 9e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain DUF3123 PF11321.8 CBY34611.1 - 0.0076 16.9 0.0 0.023 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3123) 7tm_2 PF00002.24 CBY34612.1 - 1.3e-17 63.9 7.8 8.6e-12 44.9 0.4 2.2 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) GPS PF01825.21 CBY34612.1 - 3.3e-08 33.9 5.6 3.3e-08 33.9 5.6 3.3 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif PMR5N PF14416.6 CBY34612.1 - 0.009 16.3 0.0 0.052 13.9 0.0 2.5 1 0 0 1 1 1 1 PMR5 N terminal Domain Phospholip_A2_1 PF00068.19 CBY34613.1 - 8e-18 64.9 10.1 1.1e-17 64.6 10.1 1.1 1 0 0 1 1 1 1 Phospholipase A2 Sushi PF00084.20 CBY34614.1 - 1.6 9.3 9.6 0.44 11.2 3.7 2.5 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) MAGE_N PF12440.8 CBY34614.1 - 7.1 7.4 9.7 14 6.5 9.7 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal RXLR PF16810.5 CBY34615.1 - 0.47 10.9 3.2 0.69 10.4 1.0 2.2 1 1 1 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Coprogen_oxidas PF01218.18 CBY34616.1 - 4e-122 406.6 0.1 4.4e-122 406.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M48_N PF16491.5 CBY34617.1 - 1.6e-52 178.1 12.1 1.6e-52 178.1 12.1 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CBY34617.1 - 5.5e-43 147.0 0.0 7.6e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Pro_isomerase PF00160.21 CBY34618.1 - 1.1e-24 87.5 0.3 2.1e-24 86.6 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CBY34618.1 - 2.2e-09 36.7 10.9 0.00058 19.8 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY34618.1 - 1.2e-05 25.0 6.2 0.12 12.2 1.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY34618.1 - 3.1e-05 23.8 6.3 0.044 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY34618.1 - 3.3e-05 24.4 4.0 0.001 19.7 2.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY34618.1 - 7.3e-05 23.2 3.1 7.3e-05 23.2 3.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY34618.1 - 8.6e-05 22.7 0.1 0.00023 21.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY34618.1 - 0.00011 22.8 3.0 0.0028 18.3 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Nop14 PF04147.12 CBY34618.1 - 0.003 15.9 3.7 0.003 15.9 3.7 2.0 1 1 1 2 2 2 1 Nop14-like family TPR_20 PF14561.6 CBY34618.1 - 0.0045 17.3 1.5 0.016 15.5 1.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY34618.1 - 0.0064 16.8 3.1 10 6.5 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY34618.1 - 0.05 13.8 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY34618.1 - 0.071 12.1 0.5 0.098 11.6 0.5 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY34618.1 - 0.18 12.5 6.8 3.2 8.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY34618.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.6 3 1 1 4 4 3 0 TPR repeat ANAPC3 PF12895.7 CBY34618.1 - 1.2 9.4 5.0 0.27 11.5 1.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBY34618.1 - 3.8 7.7 11.7 0.11 12.6 1.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Phos_pyr_kin PF08543.12 CBY34619.1 - 7.7e-16 58.2 0.0 1.8e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CBY34619.1 - 4.1e-05 23.0 0.0 0.008 15.5 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Carb_kinase PF01256.17 CBY34619.1 - 0.072 12.5 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate kinase PIF1 PF05970.14 CBY34620.1 - 1.3e-59 202.2 4.9 3.9e-43 148.0 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CBY34620.1 - 2.2e-16 60.1 0.0 4.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY34620.1 - 3.6e-10 40.4 0.0 3.5e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CBY34620.1 - 4.8e-06 24.8 0.2 0.00052 18.1 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.6 CBY34620.1 - 3.4e-05 24.1 0.0 0.00017 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBY34620.1 - 0.00055 19.9 0.2 0.003 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY34620.1 - 0.00074 19.9 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CBY34620.1 - 0.0014 18.2 0.1 0.0052 16.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 CBY34620.1 - 0.0017 18.8 0.3 0.0068 16.8 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBY34620.1 - 0.0022 17.8 0.2 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBY34620.1 - 0.0056 15.8 0.1 0.0097 15.0 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CBY34620.1 - 0.0075 16.0 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CBY34620.1 - 0.012 15.4 2.0 4.6 7.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CBY34620.1 - 0.012 15.6 0.0 0.054 13.5 0.0 2.1 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 CBY34620.1 - 0.023 14.4 0.3 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 CBY34620.1 - 0.037 13.5 0.1 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CBY34620.1 - 0.049 12.9 0.1 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 CBY34620.1 - 0.05 13.4 0.4 7.5 6.3 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase Hydant_A_N PF05378.13 CBY34620.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Sigma54_activ_2 PF14532.6 CBY34620.1 - 0.079 13.1 0.3 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 CBY34620.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY34620.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBY34620.1 - 0.19 12.2 1.3 0.53 10.8 0.1 2.3 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 CBY34620.1 - 0.49 9.9 3.2 0.32 10.5 0.4 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain LIN37 PF15306.6 CBY34621.1 - 2.2e-14 53.9 3.9 4e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 LIN37 Interfer-bind PF09294.10 CBY34621.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III RabGAP-TBC PF00566.18 CBY34622.1 - 2.1e-30 106.0 2.5 2.1e-29 102.8 2.5 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 CBY34623.1 - 1.9e-50 171.7 0.0 2.6e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34623.1 - 2.3e-20 73.0 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBY34623.1 - 0.00027 20.6 0.3 0.00061 19.4 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY34623.1 - 0.0039 17.2 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY34623.1 - 0.0044 16.4 0.2 0.51 9.6 0.2 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY34623.1 - 0.0064 15.9 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY34623.1 - 0.009 15.6 0.3 0.15 11.6 0.0 2.2 1 1 1 2 2 2 1 RIO1 family ABC1 PF03109.16 CBY34623.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family RabGAP-TBC PF00566.18 CBY34624.1 - 2.5e-29 102.5 0.7 2.5e-29 102.5 0.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Syntaxin_2 PF14523.6 CBY34624.1 - 0.078 13.4 2.2 0.17 12.3 2.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Pkinase PF00069.25 CBY34625.1 - 5.7e-07 29.2 0.8 6.6e-07 29.0 0.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34625.1 - 0.0036 16.6 0.1 0.0048 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 CBY34625.1 - 0.065 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 CBY34626.1 - 3.9e-38 131.3 0.0 5e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34626.1 - 5.1e-13 48.9 0.0 6.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CBY34626.1 - 0.00022 20.9 0.1 0.00036 20.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY34626.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY34626.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY34626.1 - 0.048 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 CBY34626.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 CBY34627.1 - 7.4e-40 137.0 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34627.1 - 6.2e-14 51.9 0.0 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY34627.1 - 5.6e-05 22.6 0.4 0.00013 21.4 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY34627.1 - 0.00039 20.1 0.3 0.00062 19.4 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY34627.1 - 0.0047 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY34627.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Ca_hom_mod PF14798.6 CBY34628.1 - 0.0097 15.0 0.3 0.0097 15.0 0.3 1.5 1 1 1 2 2 2 1 Calcium homeostasis modulator Shisa PF13908.6 CBY34628.1 - 0.012 15.9 2.4 0.017 15.4 2.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CBY34628.1 - 0.078 11.4 1.3 0.099 11.0 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 CBY34628.1 - 0.088 13.8 0.1 0.17 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3899 PF13038.6 CBY34628.1 - 0.78 10.3 2.1 1.1 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) TRAP-gamma PF07074.12 CBY34628.1 - 2.9 7.4 6.9 2.7 7.5 0.2 2.1 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Spc7 PF08317.11 CBY34629.1 - 0.0035 16.3 35.2 0.12 11.2 23.5 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CBY34629.1 - 0.16 11.9 41.4 1 9.3 13.1 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 CBY34629.1 - 0.25 11.1 39.4 9.1 6.0 26.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Taxilin PF09728.9 CBY34629.1 - 0.4 9.8 34.8 0.57 9.3 34.8 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Baculo_PEP_C PF04513.12 CBY34629.1 - 1.2 9.1 10.2 1.8 8.6 3.2 3.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CBY34629.1 - 2.7 7.3 40.3 1.6 8.1 30.9 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 CBY34629.1 - 6.4 7.2 32.2 2.7e+03 -1.4 31.6 2.3 1 1 0 1 1 1 0 Fez1 CUB PF00431.20 CBY34631.1 - 2.7e-12 47.0 1.3 2.9e-08 34.0 0.0 2.6 2 1 1 3 3 3 2 CUB domain CUB_2 PF02408.20 CBY34631.1 - 0.00015 21.5 0.1 0.0036 17.1 0.0 2.3 2 0 0 2 2 2 1 CUB-like domain LamB PF02264.15 CBY34631.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 LamB porin DnaJ PF00226.31 CBY34632.1 - 7.8e-08 32.3 0.0 0.003 17.6 0.0 2.9 1 1 1 2 2 2 2 DnaJ domain HAUS6_N PF14661.6 CBY34632.1 - 0.0099 15.5 2.5 0.015 14.9 2.5 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus FlxA PF14282.6 CBY34632.1 - 0.02 14.9 4.3 0.033 14.2 4.3 1.4 1 0 0 1 1 1 0 FlxA-like protein RPT PF13446.6 CBY34632.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein FbpA PF05833.11 CBY34632.1 - 0.11 11.3 6.1 0.18 10.6 6.1 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1943 PF09172.11 CBY34632.1 - 0.84 8.8 3.8 1 8.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF724 PF05266.14 CBY34632.1 - 3.3 7.5 12.4 4.9 6.9 12.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Mg296 PF09644.10 CBY34633.1 - 0.05 13.7 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Mg296 protein PDZ PF00595.24 CBY34634.1 - 4.6e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY34634.1 - 1.4e-05 24.9 0.0 3.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Utp11 PF03998.13 CBY34635.1 - 3.3e-47 161.5 23.7 3.8e-47 161.3 23.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CBY34635.1 - 4.1 6.7 7.8 0.21 10.9 0.3 2.2 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 IPP-2 PF04979.14 CBY34635.1 - 6.1 7.6 13.9 0.089 13.5 5.7 2.0 2 1 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) PAT1 PF09770.9 CBY34636.1 - 6.6e-05 21.4 1.2 0.01 14.1 0.1 2.9 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF900 PF05990.12 CBY34636.1 - 0.039 13.5 0.3 6.2 6.2 0.0 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) TFIIA PF03153.13 CBY34638.1 - 1.3 9.0 14.9 2.2 8.2 14.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CUB PF00431.20 CBY34639.1 - 5.9e-11 42.7 0.2 3.1e-09 37.2 0.2 2.5 1 1 0 1 1 1 1 CUB domain ShK PF01549.24 CBY34640.1 - 1.7e-10 41.2 24.4 2.4e-06 28.0 8.2 4.5 5 1 0 5 5 5 2 ShK domain-like TSP_1 PF00090.19 CBY34640.1 - 1.7e-07 31.3 28.7 1e-05 25.6 9.3 4.4 3 2 1 4 4 4 2 Thrombospondin type 1 domain ERM PF00769.19 CBY34641.1 - 9.5e-28 97.7 8.0 3.1e-25 89.4 1.3 2.2 2 0 0 2 2 2 2 Ezrin/radixin/moesin family RhoGEF67_u1 PF16615.5 CBY34641.1 - 0.15 12.6 0.4 0.15 12.6 0.4 3.3 3 0 0 3 3 3 0 Unstructured region one on RhoGEF 6 and 7 BicD PF09730.9 CBY34642.1 - 0.064 11.7 33.2 0.075 11.4 33.2 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ERM PF00769.19 CBY34642.1 - 0.66 9.8 59.1 7.4 6.3 59.3 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FERM_M PF00373.18 CBY34643.1 - 2.4e-28 98.9 0.4 4.8e-28 97.9 0.4 1.6 1 0 0 1 1 1 1 FERM central domain FERM_C PF09380.10 CBY34643.1 - 1.3e-25 89.6 0.2 1.2e-24 86.5 0.0 2.4 2 1 0 2 2 2 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY34643.1 - 7.9e-15 54.6 0.3 6.8e-14 51.6 0.2 2.5 3 0 0 3 3 3 1 FERM N-terminal domain RRM_1 PF00076.22 CBY34644.1 - 5e-12 45.5 0.0 7.7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY34644.1 - 0.0034 17.0 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S1FA PF04689.13 CBY34646.1 - 0.076 13.2 0.7 0.099 12.8 0.7 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA OAD_gamma PF04277.13 CBY34646.1 - 0.17 12.5 0.1 0.18 12.4 0.1 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain EMP24_GP25L PF01105.24 CBY34648.1 - 0.027 14.4 0.3 0.047 13.6 0.3 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4030 PF13222.6 CBY34648.1 - 0.028 14.6 0.7 0.048 13.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) Dynamin_N PF00350.23 CBY34649.1 - 1.5e-09 38.1 0.1 2e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY34649.1 - 6.2e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY34649.1 - 0.00044 19.8 0.1 0.001 18.6 0.0 1.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY34649.1 - 0.0044 16.9 0.2 0.035 14.0 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CBY34649.1 - 0.0053 16.1 0.6 1.3 8.3 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 CBY34649.1 - 0.01 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CBY34649.1 - 0.011 15.0 0.2 0.053 12.8 0.1 2.0 2 1 0 2 2 2 0 Septin KAP_NTPase PF07693.14 CBY34649.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Erf4 PF10256.9 CBY34650.1 - 2.1e-17 63.3 0.1 2.5e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ada3 PF10198.9 CBY34651.1 - 0.011 15.9 13.0 0.015 15.4 11.7 1.9 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 AltA1 PF16541.5 CBY34653.1 - 0.22 12.4 5.6 0.2 12.5 0.7 2.2 1 1 1 2 2 2 0 Alternaria alternata allergen 1 Pkinase PF00069.25 CBY34654.1 - 6.1e-50 170.0 0.0 1.6e-49 168.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34654.1 - 1.9e-22 79.8 0.0 3.1e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY34654.1 - 0.039 13.9 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY34654.1 - 0.045 13.4 0.2 6.9 6.2 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CBY34654.1 - 0.054 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY34654.1 - 0.057 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Collagen PF01391.18 CBY34655.1 - 4.4e-16 58.4 54.4 5.3e-10 38.9 21.9 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF3504 PF12012.8 CBY34656.1 - 3.6e-22 79.0 0.0 1.4e-21 77.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) Uteroglobin PF01099.17 CBY34656.1 - 0.026 14.9 0.6 0.075 13.4 0.6 1.8 1 0 0 1 1 1 0 Uteroglobin family Collagen PF01391.18 CBY34657.1 - 3.2e-75 247.8 295.4 3.1e-09 36.4 27.7 11.2 4 4 6 10 10 10 10 Collagen triple helix repeat (20 copies) zf-C2H2 PF00096.26 CBY34659.1 - 5.4e-17 61.2 19.2 7.4e-07 29.3 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY34659.1 - 8.5e-11 41.8 17.4 0.0031 18.2 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY34659.1 - 1.1e-10 41.4 20.3 1.3e-07 31.7 1.4 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.6 CBY34659.1 - 1.4e-05 24.7 5.6 1.4e-05 24.7 5.6 4.3 5 1 0 5 5 5 1 C2H2-type zinc-finger domain DUF3268 PF11672.8 CBY34659.1 - 0.022 15.1 5.4 0.036 14.4 4.4 1.9 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C2H2_jaz PF12171.8 CBY34659.1 - 0.031 14.6 14.3 0.22 11.9 0.1 3.9 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY34659.1 - 0.056 13.5 0.3 0.056 13.5 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_7 PF15269.6 CBY34659.1 - 0.55 10.4 5.6 0.21 11.7 1.2 2.3 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_2 PF12756.7 CBY34659.1 - 0.91 9.9 15.3 1.6 9.1 0.9 3.5 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY34659.1 - 2.2 8.1 8.9 1.5 8.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DZR PF12773.7 CBY34659.1 - 3.3 7.8 7.5 26 4.9 7.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 CBY34659.1 - 5 7.5 13.9 15 6.0 9.9 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding F-box-like PF12937.7 CBY34660.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sulfotransfer_2 PF03567.14 CBY34661.1 - 3.5e-10 40.2 3.9 3.5e-10 40.2 3.9 1.8 2 1 0 2 2 2 1 Sulfotransferase family DUF2334 PF10096.9 CBY34661.1 - 0.0084 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Sulfotransfer_1 PF00685.27 CBY34661.1 - 0.011 15.3 0.2 0.045 13.2 0.2 2.0 1 1 0 1 1 1 0 Sulfotransferase domain PLAC8 PF04749.17 CBY34662.1 - 1.4e-21 77.3 14.2 1.6e-21 77.1 14.2 1.0 1 0 0 1 1 1 1 PLAC8 family bZIP_1 PF00170.21 CBY34663.1 - 0.017 15.2 5.9 0.081 13.0 1.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor PspB PF06667.12 CBY34663.1 - 0.017 15.2 1.0 0.017 15.2 1.0 1.7 2 0 0 2 2 1 0 Phage shock protein B Phage_HK97_TLTM PF06120.11 CBY34663.1 - 0.02 14.1 4.1 0.025 13.8 4.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein ATG16 PF08614.11 CBY34663.1 - 0.024 14.9 5.1 0.024 14.9 5.1 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 CBY34663.1 - 0.087 12.1 2.6 0.11 11.7 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 CBY34663.1 - 0.14 12.6 5.9 0.21 12.0 0.7 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Wtap PF17098.5 CBY34663.1 - 0.21 11.5 5.8 39 4.2 5.8 2.3 1 1 0 1 1 1 0 WTAP/Mum2p family SIR4_SID PF16991.5 CBY34663.1 - 0.25 11.4 2.7 0.33 11.0 2.7 1.2 1 0 0 1 1 1 0 Sir4 SID domain Seadorna_VP6 PF07407.11 CBY34663.1 - 0.25 10.2 1.1 3.9 6.3 0.0 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein Exonuc_VII_L PF02601.15 CBY34663.1 - 0.45 10.0 4.8 0.52 9.8 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CBY34663.1 - 0.49 10.6 7.3 0.28 11.4 4.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY34663.1 - 0.54 9.6 5.0 0.73 9.1 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DsrD PF08679.11 CBY34663.1 - 0.62 10.4 3.7 1.9 8.8 0.4 2.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) UPF0242 PF06785.11 CBY34663.1 - 0.71 10.0 12.8 0.068 13.3 5.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 CBY34663.1 - 0.73 9.9 10.2 2.6 8.1 5.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 CBY34663.1 - 1 10.1 6.5 8.6 7.1 0.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 CBY34663.1 - 1.8 9.2 8.5 0.43 11.2 1.8 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 CBY34663.1 - 1.9 7.5 6.1 2.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2015 PF09435.10 CBY34663.1 - 2.5 8.0 6.3 1.1 9.1 3.7 1.8 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF2015) Csm1_N PF18504.1 CBY34663.1 - 4.3 7.8 10.8 1.1 9.6 3.5 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF16 PF01519.16 CBY34663.1 - 7.4 7.1 10.0 3.6 8.1 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Asparaginase PF00710.20 CBY34664.1 - 6.7e-45 153.0 0.0 1.2e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 CBY34664.1 - 1.2e-24 86.7 0.0 4.4e-11 43.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 CBY34664.1 - 2e-21 76.3 0.2 9.8e-21 74.1 0.1 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 CBY34664.1 - 3e-21 75.5 0.1 1.2e-06 28.9 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY34664.1 - 6.6e-18 64.3 0.0 9.7e-06 25.8 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CBY34664.1 - 6.9e-17 59.8 0.0 4.3e-05 23.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CBY34664.1 - 2.2e-13 50.2 0.1 8.9e-08 32.3 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF2389 PF09493.10 CBY34664.1 - 0.023 15.3 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) AA_permease_2 PF13520.6 CBY34665.1 - 7.4e-30 104.1 29.2 8.1e-30 104.0 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY34665.1 - 1.6e-11 43.5 24.7 2e-11 43.2 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF515 PF04415.12 CBY34665.1 - 0.44 8.9 0.9 0.56 8.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) DUF4776 PF16003.5 CBY34666.1 - 0.0091 15.0 1.3 0.0098 14.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4776) zf-CCHC PF00098.23 CBY34666.1 - 0.11 12.6 0.4 0.2 11.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle SNAD2 PF18745.1 CBY34667.1 - 0.055 13.2 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 SERTA PF06031.13 CBY34669.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 SERTA motif DUF3882 PF07066.11 CBY34670.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 1 0 1 1 1 0 Lactococcus phage M3 protein RT_RNaseH PF17917.1 CBY34671.1 - 1.5e-29 102.4 0.0 3.4e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY34671.1 - 1.4e-28 98.8 0.0 2.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY34671.1 - 1.3e-10 41.2 0.1 6e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY34671.1 - 7.4e-07 29.4 0.2 9.8e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_thumb PF06817.14 CBY34671.1 - 0.035 14.0 0.3 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Asp_protease_2 PF13650.6 CBY34671.1 - 0.16 12.7 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease BTB_2 PF02214.22 CBY34672.1 - 2.8e-15 56.4 0.0 4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CBY34672.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain SurA_N_3 PF13624.6 CBY34673.1 - 0.98 9.2 3.6 0.56 10.0 0.7 2.0 2 0 0 2 2 2 0 SurA N-terminal domain Macoilin PF09726.9 CBY34673.1 - 2.9 6.3 17.5 2.8 6.4 17.5 1.2 1 0 0 1 1 1 0 Macoilin family NDUF_B12 PF08122.12 CBY34676.1 - 1.4 9.0 4.0 11 6.1 0.0 3.9 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family SH3_1 PF00018.28 CBY34678.1 - 3.7e-54 180.1 6.4 5.5e-14 51.5 0.1 4.6 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CBY34678.1 - 4.3e-51 170.6 2.3 1.4e-13 50.5 0.1 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CBY34678.1 - 9.7e-42 140.5 0.2 6.1e-13 48.2 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain RhoGEF PF00621.20 CBY34678.1 - 1e-21 78.0 0.3 2.4e-21 76.8 0.3 1.7 1 0 0 1 1 1 1 RhoGEF domain EF-hand_4 PF12763.7 CBY34678.1 - 3.1e-20 72.1 0.0 2.1e-10 40.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY34678.1 - 2.5e-10 39.2 0.3 5e-05 22.6 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY34678.1 - 2.3e-07 30.2 0.1 0.005 16.7 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY34678.1 - 5.5e-07 30.0 0.0 0.0003 21.2 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY34678.1 - 2.6e-06 27.2 0.1 0.041 13.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY34678.1 - 8.4e-05 21.9 0.1 0.002 17.6 0.0 2.5 2 0 0 2 2 2 1 EF hand PH_13 PF16652.5 CBY34678.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 1 1 Pleckstrin homology domain PH PF00169.29 CBY34678.1 - 0.00047 20.6 0.1 0.0021 18.6 0.0 2.1 2 0 0 2 2 2 1 PH domain SH3_3 PF08239.11 CBY34678.1 - 0.002 18.4 4.0 0.23 11.8 0.0 3.7 4 0 0 4 4 3 1 Bacterial SH3 domain SH3_16 PF18348.1 CBY34678.1 - 0.0026 17.5 0.3 0.29 10.9 0.0 3.5 3 0 0 3 3 3 1 Bacterial dipeptidyl-peptidase Sh3 domain DUF4648 PF15505.6 CBY34678.1 - 0.016 16.1 0.0 0.72 10.8 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) Folliculin PF11704.8 CBY34679.1 - 0.04 13.8 0.2 0.05 13.5 0.2 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Galactosyl_T PF01762.21 CBY34683.1 - 3.8e-11 43.2 0.0 1.2e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.21 CBY34684.1 - 1.5e-13 51.0 0.3 2.6e-13 50.2 0.3 1.4 1 0 0 1 1 1 1 Galactosyltransferase FliW PF02623.15 CBY34684.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 FliW protein ATG16 PF08614.11 CBY34687.1 - 0.027 14.7 19.0 0.063 13.5 6.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) zf-RING_10 PF16685.5 CBY34687.1 - 0.28 11.3 6.3 0.07 13.3 2.2 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 AAA_11 PF13086.6 CBY34687.1 - 1.5 8.5 11.2 2 8.2 11.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 CBY34687.1 - 2.7 7.2 16.8 0.93 8.7 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 CBY34687.1 - 3.6 8.0 18.6 1.8 9.0 4.0 2.2 1 1 1 2 2 2 0 Fez1 Seadorna_VP6 PF07407.11 CBY34687.1 - 5.3 5.9 9.7 0.62 8.9 0.5 2.2 1 1 1 2 2 2 0 Seadornavirus VP6 protein APG6_N PF17675.1 CBY34687.1 - 9.4 6.8 21.7 7.2 7.2 14.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 CBY34689.1 - 3.6e-24 85.5 0.0 1.2e-23 83.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34689.1 - 8e-15 54.8 0.0 2.8e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase MIF4G PF02854.19 CBY34689.1 - 3e-11 43.4 1.9 3e-11 43.4 1.9 3.3 3 1 0 3 3 3 1 MIF4G domain DUF241 PF03087.14 CBY34689.1 - 0.017 15.0 11.0 0.08 12.8 7.7 2.6 2 0 0 2 2 2 0 Arabidopsis protein of unknown function W2 PF02020.18 CBY34689.1 - 0.19 11.9 2.6 0.47 10.6 0.1 2.5 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon bZIP_2 PF07716.15 CBY34689.1 - 1.1 9.4 11.8 6.1 7.0 0.1 3.3 2 1 0 2 2 2 0 Basic region leucine zipper Glyco_hydro_cc PF11790.8 CBY34690.1 - 3.9e-08 33.2 0.1 6.3e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FG-GAP PF01839.23 CBY34691.1 - 0.0035 17.4 6.0 0.022 14.9 1.3 3.8 4 0 0 4 4 4 1 FG-GAP repeat Integrin_alpha2 PF08441.12 CBY34691.1 - 0.0065 15.4 11.3 0.016 14.2 6.0 2.9 2 1 0 2 2 2 1 Integrin alpha VCBS PF13517.6 CBY34691.1 - 0.0069 17.0 0.9 0.024 15.2 0.5 2.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAP17 PF15807.5 CBY34691.1 - 0.57 10.4 1.8 0.53 10.5 0.1 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ASD2 PF08687.11 CBY34694.1 - 3.8e-09 36.5 0.0 4.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 WD40 PF00400.32 CBY34695.1 - 6.8e-11 42.6 4.9 0.0057 17.5 0.0 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34695.1 - 0.0011 19.2 0.0 0.26 11.6 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY34695.1 - 0.0082 15.5 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 1 WD40-like domain Enkurin PF13864.6 CBY34696.1 - 0.013 15.9 5.1 0.013 15.9 5.1 2.5 2 0 0 2 2 2 0 Calmodulin-binding ATG16 PF08614.11 CBY34696.1 - 0.053 13.7 8.6 0.06 13.6 2.8 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1843 PF08898.10 CBY34696.1 - 0.1 13.1 3.3 0.18 12.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SLATT_4 PF18186.1 CBY34696.1 - 0.45 10.1 4.6 3.9 7.1 0.1 3.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 WbqC PF08889.11 CBY34697.1 - 0.023 14.6 0.1 0.025 14.5 0.1 1.0 1 0 0 1 1 1 0 WbqC-like protein family Serine_rich PF08824.10 CBY34697.1 - 0.045 13.7 0.1 0.051 13.6 0.1 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain VPS13_C PF16909.5 CBY34697.1 - 0.047 13.5 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal FAM70 PF14967.6 CBY34698.1 - 0.0027 17.2 2.4 0.0046 16.5 2.4 1.3 1 0 0 1 1 1 1 FAM70 protein TMEM51 PF15345.6 CBY34698.1 - 0.0055 16.6 0.1 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Transmembrane protein 51 HisKA_7TM PF16927.5 CBY34698.1 - 0.0074 16.3 2.2 0.021 14.9 2.2 1.6 1 1 0 1 1 1 1 N-terminal 7TM region of histidine kinase Trp_oprn_chp PF09534.10 CBY34698.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) T4SS_CagC PF16943.5 CBY34698.1 - 0.024 14.8 5.2 1.7 8.9 1.5 2.5 1 1 1 2 2 2 0 Cag pathogenicity island, type IV secretory system Bac_rhodopsin PF01036.18 CBY34698.1 - 0.031 13.9 3.1 0.1 12.2 3.1 1.7 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein TetR_C_23 PF17931.1 CBY34698.1 - 0.14 12.3 0.2 13 5.9 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF202 PF02656.15 CBY34698.1 - 0.5 10.9 5.7 8.5 6.9 4.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3810 PF12725.7 CBY34698.1 - 0.79 9.0 5.4 0.83 8.9 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2304 PF10066.9 CBY34698.1 - 0.81 9.9 7.8 8.9 6.6 7.7 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Jiraiya PF15038.6 CBY34698.1 - 1.1 8.6 7.5 0.92 8.9 0.1 2.4 2 1 0 2 2 2 0 Jiraiya MHYT PF03707.16 CBY34698.1 - 1.8 8.8 6.8 1.2 9.4 0.2 2.6 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat BCD PF15461.6 CBY34698.1 - 1.8 8.0 6.1 1.6 8.1 1.6 2.3 2 1 1 3 3 3 0 Beta-carotene 15,15'-dioxygenase DUF5305 PF17231.2 CBY34698.1 - 2.2 7.6 7.1 6.2 6.1 0.2 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5305) zf-H2C2_2 PF13465.6 CBY34700.1 - 9.4e-16 57.5 19.2 6.9e-10 38.9 0.5 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY34700.1 - 1.8e-13 50.1 22.9 3.4e-05 24.1 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY34700.1 - 4e-09 36.5 19.3 0.0035 18.1 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY34700.1 - 0.006 16.6 14.1 0.57 10.3 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CBY34700.1 - 0.013 15.9 8.2 0.58 10.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY34700.1 - 0.029 14.7 9.8 0.53 10.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CBY34700.1 - 0.029 14.3 7.0 0.15 12.0 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CBY34700.1 - 0.063 13.6 4.0 0.11 12.8 4.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 CBY34700.1 - 2 8.8 10.0 0.99 9.8 1.6 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BK_channel_a PF03493.18 CBY34702.1 - 5.6e-33 113.0 0.0 1.3e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 CBY34702.1 - 4.1e-17 62.2 21.7 1.1e-16 60.9 21.7 1.6 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY34702.1 - 9.3e-13 47.9 5.8 9.3e-13 47.9 5.8 3.0 3 0 0 3 3 3 1 Ion channel TrkA_N PF02254.18 CBY34702.1 - 0.0022 18.2 0.0 0.035 14.4 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain ATP_synth_reg PF14960.6 CBY34702.1 - 0.051 13.1 0.6 4.1 7.0 0.1 2.5 2 0 0 2 2 2 0 ATP synthase regulation Lig_chan PF00060.26 CBY34702.1 - 0.18 11.6 2.9 0.66 9.8 0.8 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel L27_1 PF09058.10 CBY34705.1 - 0.1 12.6 1.8 0.31 11.0 0.0 2.5 2 0 0 2 2 2 0 L27_1 ROQ_II PF18386.1 CBY34706.1 - 0.036 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Roquin II domain Zona_pellucida PF00100.23 CBY34707.1 - 7.1e-16 58.8 2.8 9.5e-16 58.4 2.8 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain LSM PF01423.22 CBY34708.1 - 1.1e-19 69.9 0.5 1.5e-19 69.4 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY34708.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Nop PF01798.18 CBY34709.1 - 3.1e-82 275.5 0.1 5.3e-82 274.7 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBY34709.1 - 1.4e-16 60.6 0.2 1.4e-16 60.6 0.2 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Fib_alpha PF08702.10 CBY34710.1 - 0.0075 16.5 10.7 0.017 15.3 4.6 2.6 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBY34710.1 - 0.0091 16.0 7.4 0.074 13.1 0.4 2.6 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 CBY34710.1 - 0.021 14.7 2.9 3.1 7.7 0.3 3.7 3 1 1 4 4 4 0 Heat shock factor binding protein 1 DUF2935 PF11155.8 CBY34710.1 - 0.027 14.8 6.1 1.1 9.6 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Apolipoprotein PF01442.18 CBY34710.1 - 0.048 13.5 3.9 0.12 12.2 2.7 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain PLC-beta_C PF08703.10 CBY34710.1 - 0.062 13.3 0.1 0.062 13.3 0.1 2.7 2 1 1 3 3 3 0 PLC-beta C terminal KilA-N PF04383.13 CBY34710.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.0 2 1 0 2 2 2 0 KilA-N domain DUF4164 PF13747.6 CBY34710.1 - 0.14 12.5 4.3 3.3 8.1 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) KIX PF02172.16 CBY34710.1 - 0.17 12.2 2.2 8.5 6.7 0.0 3.1 3 0 0 3 3 3 0 KIX domain Cytochrom_C_2 PF01322.20 CBY34710.1 - 0.17 12.8 0.4 0.17 12.8 0.4 2.2 2 1 1 3 3 3 0 Cytochrome C' DUF948 PF06103.11 CBY34710.1 - 0.4 11.0 6.9 0.37 11.1 1.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CLZ PF16526.5 CBY34710.1 - 0.97 9.8 7.1 21 5.6 0.6 3.7 2 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 4HB_MCP_1 PF12729.7 CBY34710.1 - 1.1 8.8 8.8 3 7.3 2.5 2.9 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4709 PF15821.5 CBY34710.1 - 1.3 9.4 7.8 1.1 9.5 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) LMBR1 PF04791.16 CBY34710.1 - 1.6 7.6 7.4 2.3 7.0 7.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 CBY34710.1 - 2.6 7.2 6.9 8 5.6 4.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein PAN_1 PF00024.26 CBY34711.1 - 9.2e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 CBY34711.1 - 0.026 14.6 2.4 0.044 13.9 0.3 2.2 2 0 0 2 2 2 0 PAN-like domain DUF1664 PF07889.12 CBY34711.1 - 0.22 11.6 10.5 6.2 6.9 0.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 CBY34711.1 - 1.1 9.3 11.9 0.4 10.7 0.3 3.3 3 1 0 3 3 3 0 Prefoldin subunit LLC1 PF14945.6 CBY34712.1 - 1.1e-33 116.3 5.9 1.3e-33 116.1 5.9 1.0 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein PI3K_P85_iSH2 PF16454.5 CBY34712.1 - 0.099 12.2 5.6 0.13 11.9 5.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM183 PF14886.6 CBY34712.1 - 0.11 13.2 5.4 0.29 11.9 5.4 1.7 1 1 0 1 1 1 0 FAM183A and FAM183B related AARP2CN PF08142.12 CBY34712.1 - 0.17 12.0 1.1 0.25 11.4 1.1 1.5 1 1 0 1 1 1 0 AARP2CN (NUC121) domain CCDC-167 PF15188.6 CBY34712.1 - 0.49 10.8 4.1 0.17 12.2 1.9 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TonB_2 PF13103.6 CBY34713.1 - 0.048 13.9 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 TonB C terminal ELMO_CED12 PF04727.13 CBY34714.1 - 1.1e-30 107.0 0.2 3e-30 105.7 0.1 1.7 2 1 1 3 3 3 1 ELMO/CED-12 family HSP70 PF00012.20 CBY34715.1 - 9.1e-124 413.8 3.0 1e-123 413.7 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY34715.1 - 5.5e-14 51.7 0.9 1.8e-12 46.7 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein GFRP PF06399.13 CBY34715.1 - 0.018 14.9 0.0 0.53 10.2 0.0 2.7 2 1 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) FtsA PF14450.6 CBY34715.1 - 0.037 14.4 0.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Cell division protein FtsA CRM1_C PF08767.11 CBY34716.1 - 0.0049 16.1 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 CRM1 C terminal Peptidase_S49 PF01343.18 CBY34716.1 - 0.067 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 FtsJ PF01728.19 CBY34717.1 - 1e-70 237.4 0.1 1.3e-70 237.1 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CBY34717.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CBY34717.1 - 0.098 13.7 0.0 0.38 11.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CBY34717.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CBY34717.1 - 0.17 12.6 0.0 1.3 9.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Jagunal PF07086.12 CBY34718.1 - 5e-34 118.0 1.5 5.6e-34 117.8 1.5 1.0 1 0 0 1 1 1 1 Jagunal, ER re-organisation during oogenesis CENP-H PF05837.12 CBY34719.1 - 0.016 15.6 3.1 0.016 15.6 3.1 11.0 1 1 10 12 12 12 0 Centromere protein H (CENP-H) WD40 PF00400.32 CBY34720.1 - 4.9e-10 39.8 8.1 0.01 16.7 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34720.1 - 0.0014 18.9 0.1 0.71 10.2 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GbpA_2 PF18416.1 CBY34720.1 - 0.034 14.4 0.1 0.16 12.3 0.0 2.1 3 0 0 3 3 3 0 N-acetylglucosamine binding protein domain 2 Big_3 PF07523.12 CBY34720.1 - 0.26 11.6 0.9 1.8 8.9 0.0 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Pkinase PF00069.25 CBY34721.1 - 7.4e-44 150.1 0.0 2e-43 148.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34721.1 - 3.6e-29 101.8 0.0 9.9e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase TBK1_CCD1 PF18394.1 CBY34721.1 - 5.3e-08 32.7 12.5 1.1e-07 31.7 10.8 2.3 1 1 0 1 1 1 1 TANK-binding kinase 1 coiled-coil domain 1 Pkinase_fungal PF17667.1 CBY34721.1 - 0.00084 18.2 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF2407 PF10302.9 CBY34721.1 - 0.089 13.4 0.2 0.52 10.9 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TGF_beta PF00019.20 CBY34722.1 - 4.9e-13 50.0 0.1 1e-12 48.9 0.1 1.5 1 0 0 1 1 1 1 Transforming growth factor beta like domain SR-25 PF10500.9 CBY34722.1 - 0.0018 18.0 20.7 0.0024 17.5 20.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 CBY34722.1 - 0.044 13.6 0.9 0.052 13.4 0.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.9 CBY34722.1 - 0.068 11.7 4.2 0.071 11.7 4.2 1.0 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CBY34722.1 - 0.086 11.6 3.8 0.12 11.2 3.8 1.2 1 0 0 1 1 1 0 Presenilin CCDC106 PF15794.5 CBY34722.1 - 0.3 10.8 14.3 0.43 10.3 14.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3827 PF12877.7 CBY34722.1 - 0.37 9.1 9.2 0.47 8.8 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CDC45 PF02724.14 CBY34722.1 - 0.83 7.9 11.3 1 7.6 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MFMR_assoc PF16596.5 CBY34722.1 - 1.7 9.1 9.5 3.2 8.2 9.5 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR IMUP PF15761.5 CBY34722.1 - 5.8 7.7 16.7 9.1 7.0 16.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Gln-synt_N PF03951.19 CBY34723.1 - 1.3e-15 56.9 0.0 1.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain HIPIP PF01355.17 CBY34726.1 - 0.0016 18.8 17.3 2.4 8.6 0.3 6.5 6 0 0 6 6 6 4 High potential iron-sulfur protein DUF4729 PF15866.5 CBY34726.1 - 1.5 8.1 25.9 0.17 11.2 0.1 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4729) HMG-CoA_red PF00368.18 CBY34727.1 - 1.3e-115 386.3 0.1 1.9e-115 385.8 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase ECH_2 PF16113.5 CBY34729.1 - 1.3e-113 379.9 0.0 1.5e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBY34729.1 - 8.7e-26 90.7 0.0 1.9e-25 89.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Sulfotransfer_2 PF03567.14 CBY34730.1 - 8.7e-23 81.5 0.8 1.1e-22 81.1 0.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family RNaseH_C PF09293.10 CBY34730.1 - 0.068 13.5 1.1 0.35 11.2 0.1 2.3 2 1 1 3 3 3 0 T4 RNase H, C terminal DUF4211 PF13926.6 CBY34730.1 - 0.089 12.8 0.5 0.23 11.5 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) Zona_pellucida PF00100.23 CBY34731.1 - 1.7e-21 77.2 0.1 2.2e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY34731.1 - 0.00023 21.4 12.4 0.0005 20.3 10.1 2.7 1 1 1 2 2 2 2 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.23 CBY34732.1 - 9.1e-28 97.7 3.2 1.2e-27 97.4 3.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FGF PF00167.18 CBY34733.1 - 4.2e-13 49.5 0.4 5.2e-13 49.2 0.4 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 CBY34733.1 - 1.3e-09 38.3 0.2 3.1e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Fascin domain FRG1 PF06229.12 CBY34733.1 - 0.068 12.9 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 FRG1-like domain GWT1 PF06423.12 CBY34735.1 - 0.027 14.6 3.1 0.12 12.5 3.1 2.2 1 1 0 1 1 1 0 GWT1 DUF2975 PF11188.8 CBY34735.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) zf-AN1 PF01428.16 CBY34736.1 - 2.6e-10 40.3 7.4 3.7e-10 39.8 7.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger zinc_ribbon_16 PF17034.5 CBY34736.1 - 0.01 16.0 0.3 0.015 15.5 0.2 1.3 1 1 0 1 1 1 0 Zinc-ribbon like family FTHFS PF01268.19 CBY34737.1 - 7.2e-262 869.5 0.1 7.2e-262 869.5 0.1 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CBY34737.1 - 8.4e-64 213.7 0.3 8.4e-64 213.7 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY34737.1 - 6.8e-34 116.6 0.8 1.3e-33 115.7 0.8 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.20 CBY34738.1 - 1e-120 403.8 0.0 1e-120 403.8 0.0 2.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 CBY34739.1 - 4.4e-59 200.6 0.3 9.2e-59 199.5 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 CBY34739.1 - 0.088 11.9 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Trypsin PF00089.26 CBY34740.1 - 2.2e-31 109.4 0.0 3.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.28 CBY34740.1 - 0.0003 21.1 1.1 0.00068 19.9 0.4 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain TMEM154 PF15102.6 CBY34740.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family VWA_2 PF13519.6 CBY34740.1 - 0.027 15.1 0.1 0.11 13.2 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Peptidase_M1 PF01433.20 CBY34741.1 - 5.2e-47 160.2 3.6 1.5e-46 158.7 3.6 1.8 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY34741.1 - 7e-31 107.9 3.8 7.2e-31 107.8 1.2 2.2 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain T3RM_EcoP15I_C PF18273.1 CBY34741.1 - 0.054 13.8 0.1 0.2 12.0 0.1 2.0 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain ATP-gua_Ptrans PF00217.19 CBY34744.1 - 2.8e-62 209.9 0.0 4e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY34744.1 - 2e-21 76.1 0.0 3.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Dynein_light PF01221.18 CBY34746.1 - 3.3e-44 149.1 1.1 3.7e-44 149.0 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Pkinase PF00069.25 CBY34747.1 - 9e-67 225.2 0.2 1.1e-66 225.0 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34747.1 - 4.2e-20 72.1 0.0 5.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY34747.1 - 7.6e-09 35.8 0.1 1.4e-06 28.4 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY34747.1 - 0.00027 20.3 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY34747.1 - 0.00049 19.7 1.1 0.0043 16.7 0.1 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CBY34747.1 - 0.0034 16.2 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY34747.1 - 0.048 13.0 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PRCC PF10253.9 CBY34749.1 - 4.7e-28 99.4 0.2 4.7e-28 99.4 0.2 3.4 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2462 PF09495.10 CBY34750.1 - 1.2e-11 45.1 17.6 1.4e-11 44.9 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) WD40 PF00400.32 CBY34751.1 - 1.7e-32 110.9 9.3 5.9e-09 36.4 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34751.1 - 9.8e-16 57.8 0.3 0.0049 17.1 0.0 5.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 CBY34751.1 - 3.5e-15 55.4 0.5 6.5e-15 54.5 0.5 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 CBY34751.1 - 3.3e-09 36.1 1.2 0.0086 15.1 0.0 3.9 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY34751.1 - 1.4e-08 33.8 0.0 0.013 14.2 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY34751.1 - 1.5e-05 25.0 1.4 0.017 15.0 0.2 3.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY34751.1 - 0.012 14.9 2.3 0.17 11.1 1.1 2.7 2 1 0 2 2 2 0 WD40-like domain PD40 PF07676.12 CBY34751.1 - 0.015 15.2 0.0 28 4.8 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.6 CBY34751.1 - 0.046 13.3 0.6 0.18 11.3 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) LTD PF00932.19 CBY34751.1 - 0.081 13.3 0.1 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Lamin Tail Domain Hira PF07569.11 CBY34751.1 - 0.089 12.5 0.2 16 5.1 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split Proteasome_A_N PF10584.9 CBY34751.1 - 0.12 12.1 0.3 1.1e+02 2.6 0.1 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PIG-L PF02585.17 CBY34752.1 - 5.5e-24 85.3 0.0 7.5e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ADH_N_2 PF16884.5 CBY34753.1 - 2.6e-25 88.4 0.0 2e-24 85.6 0.0 2.2 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CBY34753.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBY34753.1 - 8.1e-09 36.6 0.0 1.3e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.29 CBY34754.1 - 2.3e-08 33.8 1.9 7.1e-08 32.2 1.9 1.9 1 0 0 1 1 1 1 PHD-finger FHA PF00498.26 CBY34754.1 - 2e-06 28.0 0.0 0.0001 22.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain zf-PHD-like PF15446.6 CBY34754.1 - 0.0058 16.3 0.2 0.0058 16.3 0.2 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 CBY34754.1 - 0.0081 15.8 1.0 0.018 14.7 1.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 CBY34754.1 - 0.022 14.6 0.6 0.049 13.5 0.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CBY34754.1 - 0.029 14.5 0.1 0.067 13.3 0.1 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 CBY34754.1 - 0.076 12.6 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 PHD-finger LolA PF03548.15 CBY34756.1 - 0.004 16.9 1.2 0.0052 16.5 0.4 1.5 2 0 0 2 2 2 1 Outer membrane lipoprotein carrier protein LolA Cas9_PI PF16595.5 CBY34756.1 - 0.011 15.6 9.3 0.024 14.5 9.3 1.5 1 1 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 OEP PF02321.18 CBY34756.1 - 0.085 12.7 0.7 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Outer membrane efflux protein RasGAP PF00616.19 CBY34756.1 - 0.26 11.0 7.0 0.36 10.5 7.0 1.2 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF1664 PF07889.12 CBY34756.1 - 1.5 8.8 10.8 0.78 9.8 7.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2540 PF10802.8 CBY34757.1 - 0.28 11.3 3.6 1.6 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) zf-CpG_bind_C PF12269.8 CBY34757.1 - 0.3 10.8 2.6 0.31 10.8 0.7 1.9 2 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Hc1 PF07432.13 CBY34757.1 - 0.38 11.1 4.1 5.6 7.4 0.3 2.5 1 1 1 2 2 2 0 Histone H1-like protein Hc1 TMF_TATA_bd PF12325.8 CBY34761.1 - 0.0017 18.6 4.8 0.0017 18.6 4.8 25.5 11 5 14 26 26 26 6 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CBY34761.1 - 0.0054 16.8 0.9 0.0054 16.8 0.9 24.1 11 6 14 27 27 27 6 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 CBY34762.1 - 8e-61 205.7 0.0 1.3e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34762.1 - 7.6e-24 84.4 0.5 2.2e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34762.1 - 1.2e-09 37.9 0.4 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY34762.1 - 1.7e-07 30.8 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY34762.1 - 0.0052 16.7 0.3 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY34762.1 - 0.022 13.7 0.3 0.61 9.0 0.0 2.3 2 1 0 2 2 2 0 Haspin like kinase domain Reprolysin_3 PF13582.6 CBY34762.1 - 0.082 13.4 0.5 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Choline_kinase PF01633.20 CBY34762.1 - 0.1 12.2 1.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CBY34762.1 - 0.14 10.9 5.0 0.49 9.1 4.7 1.9 1 1 0 1 1 1 0 Fungal protein kinase Mito_fiss_reg PF05308.11 CBY34762.1 - 1.1 9.2 10.9 1.8 8.6 10.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Na_Pi_cotrans PF02690.15 CBY34763.1 - 1.8e-14 54.0 2.0 2.9e-14 53.4 2.0 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter Mucin PF01456.17 CBY34763.1 - 0.25 11.3 5.9 0.65 10.0 5.9 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SR-25 PF10500.9 CBY34763.1 - 0.28 10.7 13.6 0.19 11.3 6.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DOT1 PF08123.13 CBY34765.1 - 0.024 14.2 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 GTP_EFTU PF00009.27 CBY34766.1 - 3e-39 134.6 0.0 4.9e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CBY34766.1 - 6.1e-33 114.0 4.6 1.2e-32 113.1 4.6 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CBY34766.1 - 7.5e-23 80.6 0.0 1.7e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY34766.1 - 4.7e-22 77.8 0.0 1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBY34766.1 - 4.1e-08 33.2 0.0 9.6e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBY34766.1 - 9e-08 32.4 0.0 2.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY34766.1 - 0.00086 19.4 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CBY34766.1 - 0.063 12.9 0.0 0.27 10.8 0.0 2.1 1 1 0 1 1 1 0 Ras family VHS PF00790.19 CBY34767.1 - 2.3e-23 82.6 0.0 7.4e-23 81.0 0.0 1.9 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CBY34767.1 - 1.2e-11 44.9 0.4 2.3e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CBY34767.1 - 1.5e-10 40.5 4.2 4.2e-10 39.1 4.2 1.8 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CBY34767.1 - 5.3e-07 29.9 4.2 2.4e-06 27.7 0.3 2.5 2 0 0 2 2 2 1 GAT domain Holin_BhlA PF10960.8 CBY34767.1 - 0.084 12.8 0.5 0.25 11.3 0.5 1.7 1 0 0 1 1 1 0 BhlA holin family Cyt_c_ox_IV PF12270.8 CBY34768.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ECSCR PF15820.5 CBY34768.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF1143 PF06608.11 CBY34769.1 - 1.7e-28 99.5 3.4 2.5e-28 99.0 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) LrgB PF04172.16 CBY34770.1 - 0.0075 15.8 2.7 0.011 15.3 2.7 1.3 1 0 0 1 1 1 1 LrgB-like family DUF4199 PF13858.6 CBY34770.1 - 0.063 13.7 6.6 0.025 15.0 4.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) CDC50 PF03381.15 CBY34771.1 - 1.1e-83 280.9 0.1 1.5e-83 280.6 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.6 CBY34771.1 - 2.6 8.8 6.5 0.43 11.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) CCDC92 PF14916.6 CBY34772.1 - 1.4e-11 44.0 5.3 1.8e-11 43.6 1.1 2.3 2 0 0 2 2 2 1 Coiled-coil domain of unknown function APG6_N PF17675.1 CBY34772.1 - 0.13 12.8 10.7 0.36 11.4 0.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 CBY34772.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CBY34772.1 - 0.42 11.3 5.4 1.7 9.3 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBY34772.1 - 0.46 11.0 11.4 1.5 9.3 2.0 2.8 2 1 1 3 3 3 0 Cell division protein ZapB WD40_alt PF14077.6 CBY34772.1 - 0.55 10.2 0.1 0.55 10.2 0.1 2.7 3 0 0 3 3 3 0 Alternative WD40 repeat motif Cnn_1N PF07989.11 CBY34772.1 - 1 9.6 8.4 0.55 10.4 1.2 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DMPK_coil PF08826.10 CBY34772.1 - 1.6 8.9 11.4 3.2 7.9 1.2 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like bZIP_1 PF00170.21 CBY34772.1 - 1.8 8.7 10.1 1.4 9.1 2.8 2.9 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.15 CBY34772.1 - 2.8 7.8 7.4 3 7.7 0.7 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 CBY34772.1 - 3.6 8.1 5.7 5.1 7.6 1.0 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAA_hydrolase PF01557.18 CBY34774.1 - 2.5e-31 109.0 0.0 3.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Dynactin_p22 PF07426.11 CBY34775.1 - 5.3e-12 45.9 9.1 5.3e-12 45.9 9.1 1.4 1 1 0 1 1 1 1 Dynactin subunit p22 SlyX PF04102.12 CBY34775.1 - 0.041 14.5 5.7 9.6 6.9 0.3 3.8 1 1 2 4 4 4 0 SlyX Sulfotransfer_2 PF03567.14 CBY34775.1 - 0.07 13.0 0.2 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Sulfotransferase family Snapin_Pallidin PF14712.6 CBY34775.1 - 3.4 8.2 8.9 1.1 9.7 1.2 3.1 1 1 2 3 3 3 0 Snapin/Pallidin TTL PF03133.15 CBY34776.1 - 3.5e-105 351.4 2.3 4.4e-105 351.0 2.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY34776.1 - 4.3e-08 32.7 0.0 1.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY34776.1 - 0.00012 21.5 0.0 0.00089 18.6 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Inhibitor_I66 PF16850.5 CBY34776.1 - 0.025 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I66 RimK PF08443.11 CBY34776.1 - 0.083 12.5 0.0 0.68 9.5 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Ish1 PF10281.9 CBY34776.1 - 0.094 13.0 2.1 2.9 8.3 0.0 3.4 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein ING PF12998.7 CBY34777.1 - 4.9e-06 27.1 4.5 1.2e-05 25.8 4.5 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1539 PF07560.11 CBY34777.1 - 0.01 15.9 0.4 0.023 14.8 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) UPF0561 PF10573.9 CBY34777.1 - 0.058 13.5 1.5 0.14 12.3 0.4 2.0 1 1 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF1664 PF07889.12 CBY34777.1 - 0.5 10.4 2.7 15 5.7 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KNOX2 PF03791.13 CBY34777.1 - 0.54 9.8 3.6 0.18 11.3 0.3 2.0 2 0 0 2 2 2 0 KNOX2 domain BLI1 PF17324.2 CBY34777.1 - 1.3 9.7 9.1 0.28 11.8 1.4 2.3 1 1 1 2 2 2 0 BLOC-1 interactor 1 COX5B PF01215.19 CBY34778.1 - 0.0063 16.2 0.0 0.019 14.7 0.0 1.7 1 1 1 2 2 2 1 Cytochrome c oxidase subunit Vb Tfb2 PF03849.14 CBY34779.1 - 2.1e-105 352.6 0.8 3.1e-105 352.0 0.8 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CBY34779.1 - 1.1e-23 83.5 1.8 4e-23 81.6 1.5 2.3 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CBY34779.1 - 6.1e-05 23.2 0.1 0.00022 21.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LRR_6 PF13516.6 CBY34780.1 - 2.5e-24 83.2 36.2 0.0061 16.5 0.0 13.1 14 0 0 14 14 14 8 Leucine Rich repeat LRR_1 PF00560.33 CBY34780.1 - 8.2e-09 34.8 15.6 34 5.5 0.0 12.0 12 0 0 12 12 12 0 Leucine Rich Repeat LRR_4 PF12799.7 CBY34780.1 - 9.6e-09 35.4 32.6 0.001 19.4 0.5 10.8 8 3 5 13 13 13 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY34780.1 - 0.00043 20.0 29.7 0.0037 17.0 2.2 8.9 8 2 2 10 10 10 4 Leucine rich repeat RanGAP1_C PF07834.11 CBY34780.1 - 0.012 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 RanGAP1 C-terminal domain Lactamase_B_5 PF14597.6 CBY34780.1 - 0.026 14.0 1.0 0.045 13.2 0.3 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily T-box PF00907.22 CBY34781.1 - 9e-49 166.2 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 T-box Troponin PF00992.20 CBY34783.1 - 6.8e-24 84.7 33.1 3.2e-21 76.0 25.6 2.0 1 1 1 2 2 2 2 Troponin FXa_inhibition PF14670.6 CBY34784.1 - 5.5e-08 33.0 7.6 9.3e-08 32.2 7.6 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY34784.1 - 0.041 13.8 0.6 0.074 13.0 0.6 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.27 CBY34784.1 - 1.1 9.6 7.1 2.8 8.3 7.1 1.7 1 0 0 1 1 1 0 EGF-like domain E_raikovi_mat PF06360.11 CBY34784.1 - 6.3 7.3 7.8 59 4.2 6.7 2.5 1 1 1 2 2 2 0 Euplotes raikovi mating pheromone Vps8 PF12816.7 CBY34785.1 - 0.038 13.5 0.0 17 4.9 0.0 3.2 2 1 1 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 MDD_C PF18376.1 CBY34786.1 - 0.087 12.6 0.2 0.15 11.8 0.1 1.3 1 1 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain PRO8NT PF08082.11 CBY34786.1 - 0.2 11.6 2.7 0.22 11.4 2.7 1.0 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Pep_M12B_propep PF01562.19 CBY34788.1 - 1.8e-28 99.5 1.1 3.5e-28 98.6 1.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CBY34788.1 - 4.6e-20 72.4 0.0 1e-19 71.3 0.0 1.6 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 CBY34788.1 - 8.5e-15 55.0 6.8 8.5e-15 55.0 6.8 5.6 6 2 0 6 6 6 2 ADAM cysteine-rich domain Reprolysin_5 PF13688.6 CBY34788.1 - 2.6e-14 53.8 0.3 6.6e-14 52.5 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 TSP_1 PF00090.19 CBY34788.1 - 8.1e-09 35.6 92.6 7.2e-06 26.1 8.8 9.0 9 2 0 9 9 9 5 Thrombospondin type 1 domain Reprolysin_3 PF13582.6 CBY34788.1 - 1.4e-07 32.1 0.2 2.6e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY34788.1 - 1.6e-07 31.2 0.1 2.9e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY34788.1 - 6.2e-07 29.5 0.2 1.1e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PLAC PF08686.11 CBY34788.1 - 2.5e-05 24.9 8.0 2.5e-05 24.9 8.0 3.0 2 0 0 2 2 2 1 PLAC (protease and lacunin) domain Peptidase_M57 PF12388.8 CBY34788.1 - 0.14 11.8 0.3 0.3 10.7 0.3 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Pkinase PF00069.25 CBY34790.1 - 1.2e-35 123.1 0.0 2.5e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34790.1 - 3.9e-30 105.0 0.0 6.9e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CBY34790.1 - 2.6e-23 81.5 38.4 6.4e-07 29.1 2.7 7.2 7 1 0 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 CBY34790.1 - 4.4e-17 61.9 50.7 0.0002 21.7 4.2 8.6 7 2 2 9 9 8 6 Leucine Rich repeats (2 copies) COR PF16095.5 CBY34790.1 - 1.2e-12 48.1 0.0 6.4e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 CBY34790.1 - 1.1e-09 38.5 0.0 3.1e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kinase-like PF14531.6 CBY34790.1 - 0.00045 19.6 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like LRR_9 PF14580.6 CBY34790.1 - 0.0012 18.4 16.4 0.036 13.6 1.6 4.3 3 1 1 4 4 4 2 Leucine-rich repeat AAA_18 PF13238.6 CBY34790.1 - 0.0061 17.1 0.0 0.15 12.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBY34790.1 - 0.012 15.8 0.0 7.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain LRR_1 PF00560.33 CBY34790.1 - 0.1 13.2 34.9 0.44 11.3 0.6 10.0 10 1 1 11 11 8 0 Leucine Rich Repeat DUF5344 PF17279.2 CBY34790.1 - 0.11 13.1 0.5 93 3.7 0.0 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5344) AAA_29 PF13555.6 CBY34790.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY34790.1 - 0.69 10.3 3.5 0.9 9.9 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain ATP-synt_C PF00137.21 CBY34791.1 - 2.2e-11 43.9 14.0 3.1e-11 43.5 14.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit C DUF2228 PF10228.9 CBY34792.1 - 9.5e-52 176.2 0.3 2.6e-39 135.5 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2228) JmjN PF02375.17 CBY34792.1 - 0.057 13.4 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 jmjN domain BSD PF03909.17 CBY34793.1 - 2.4e-19 69.1 1.3 2e-13 50.1 0.1 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CBY34793.1 - 4e-15 55.9 0.1 9.2e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain MFS_1 PF07690.16 CBY34793.1 - 1.6e-08 33.9 22.4 1.6e-08 33.9 22.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily SRP1_TIP1 PF00660.17 CBY34793.1 - 0.023 14.8 0.1 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 Seripauperin and TIP1 family Vma12 PF11712.8 CBY34793.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.9 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box PF00646.33 CBY34794.1 - 0.00011 21.9 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY34794.1 - 0.00059 19.7 0.0 0.00098 19.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF5511 PF17630.2 CBY34795.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5511) PLAC PF08686.11 CBY34796.1 - 0.019 15.7 0.1 0.04 14.7 0.1 1.6 1 0 0 1 1 1 0 PLAC (protease and lacunin) domain YmzC PF14157.6 CBY34796.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 YmzC-like protein KH_1 PF00013.29 CBY34797.1 - 1.7e-14 53.4 0.5 4.6e-14 52.0 0.5 1.7 1 0 0 1 1 1 1 KH domain DUF1338 PF07063.13 CBY34797.1 - 0.0011 18.2 0.0 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1338) Ank_2 PF12796.7 CBY34797.1 - 0.037 14.6 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY34797.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY34797.1 - 0.18 12.4 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) KH_4 PF13083.6 CBY34797.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.8 3 0 0 3 3 3 0 KH domain FAM163 PF15069.6 CBY34798.1 - 0.00012 22.6 0.1 0.00015 22.3 0.1 1.2 1 0 0 1 1 1 1 FAM163 family Prominin PF05478.11 CBY34798.1 - 0.034 12.1 1.7 0.042 11.8 1.7 1.1 1 0 0 1 1 1 0 Prominin RCC1 PF00415.18 CBY34800.1 - 5.5e-23 81.3 0.2 7.8e-09 36.0 0.1 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CBY34800.1 - 7.2e-18 64.8 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain RCC1_2 PF13540.6 CBY34800.1 - 1.9e-11 43.4 7.3 8.7e-06 25.4 0.3 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Stathmin PF00836.19 CBY34800.1 - 0.025 14.6 0.6 0.025 14.6 0.6 2.1 2 0 0 2 2 2 0 Stathmin family Vault PF01505.18 CBY34800.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain BTB PF00651.31 CBY34801.1 - 6.9e-18 64.9 0.0 2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 CBY34801.1 - 0.008 16.7 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Stathmin PF00836.19 CBY34801.1 - 0.015 15.3 0.6 0.015 15.3 0.6 2.2 2 0 0 2 2 2 0 Stathmin family RhoGAP PF00620.27 CBY34802.1 - 1.5e-16 60.6 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBY34802.1 - 1.6e-09 37.7 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1573 PF07610.11 CBY34802.1 - 0.085 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PapD-like PF14874.6 CBY34802.1 - 0.091 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like Condensation PF00668.20 CBY34803.1 - 0.09 11.4 0.0 0.2 10.3 0.0 1.4 1 1 0 1 1 1 0 Condensation domain DUF4562 PF15123.6 CBY34804.1 - 1.3e-09 38.0 0.0 1.3e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) Collagen PF01391.18 CBY34805.1 - 2.2e-77 254.7 273.8 1.2e-08 34.5 25.2 10.7 3 2 5 9 9 9 8 Collagen triple helix repeat (20 copies) C4 PF01413.19 CBY34805.1 - 6.1e-39 132.8 13.2 2.9e-20 72.7 1.7 3.0 2 1 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen PMP22_Claudin PF00822.20 CBY34806.1 - 1.5e-10 41.2 6.2 2.4e-10 40.5 6.2 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY34806.1 - 1e-05 25.8 1.2 1e-05 25.8 1.2 1.4 2 0 0 2 2 2 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY34806.1 - 0.0035 17.1 13.3 0.0081 15.9 12.7 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction LrgA PF03788.14 CBY34806.1 - 0.032 14.2 1.8 2.1 8.3 0.8 2.3 2 0 0 2 2 2 0 LrgA family Cyt_bd_oxida_II PF02322.15 CBY34806.1 - 0.045 13.1 7.8 0.081 12.3 7.8 1.4 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II 7TMR-DISM_7TM PF07695.11 CBY34806.1 - 0.064 13.2 14.0 0.095 12.6 13.3 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling YoqO PF14037.6 CBY34806.1 - 0.12 12.9 0.5 0.12 12.9 0.5 2.1 3 0 0 3 3 3 0 YoqO-like protein MIG-14_Wnt-bd PF06664.12 CBY34806.1 - 0.84 8.8 10.9 0.11 11.7 6.4 1.6 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF1218 PF06749.12 CBY34806.1 - 1.6 9.3 7.7 1.3e+02 3.2 5.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) Claudin_3 PF06653.11 CBY34806.1 - 3.4 7.6 10.2 14 5.6 10.3 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like YwiC PF14256.6 CBY34806.1 - 5.9 7.2 11.3 29 5.0 7.1 2.7 2 1 0 2 2 2 0 YwiC-like protein D5_N PF08706.11 CBY34807.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 D5 N terminal like Fun_ATP-synt_8 PF05933.13 CBY34808.1 - 0.091 12.9 0.8 0.18 12.0 0.8 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) O-FucT PF10250.9 CBY34809.1 - 0.006 16.3 0.1 0.009 15.7 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sulfotransfer_1 PF00685.27 CBY34810.1 - 0.00013 21.5 0.1 0.0002 20.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain O-FucT PF10250.9 CBY34811.1 - 0.054 13.2 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Sad1_UNC PF07738.13 CBY34814.1 - 4.6e-31 107.6 0.0 5.4e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 CBY34815.1 - 5.5e-47 160.3 0.0 7.6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34815.1 - 7.3e-18 64.8 0.0 1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY34815.1 - 1.3e-08 34.5 0.0 2.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY34815.1 - 9.8e-06 25.1 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY34815.1 - 1.8e-05 23.9 0.2 3.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY34815.1 - 0.00081 18.3 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY34815.1 - 0.0079 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY34815.1 - 0.01 15.4 0.6 0.015 14.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase EGF_CA PF07645.15 CBY34817.1 - 4 7.7 7.8 4.4 7.6 5.5 2.3 2 1 0 2 2 2 0 Calcium-binding EGF domain HMG_box_2 PF09011.10 CBY34818.1 - 6.3e-32 110.0 14.0 4e-16 59.4 2.3 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CBY34818.1 - 2.9e-30 104.5 11.9 1.3e-17 64.0 3.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box MlaC PF05494.12 CBY34818.1 - 0.0056 16.4 1.2 0.094 12.5 0.2 2.1 2 0 0 2 2 2 1 MlaC protein HMG_box_5 PF14887.6 CBY34818.1 - 0.0077 16.2 2.7 0.0077 16.2 2.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 FTCD_C PF04961.12 CBY34818.1 - 2.1 8.1 8.4 3.9 7.2 0.3 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase eIF-5a PF01287.20 CBY34819.1 - 6.7e-22 77.4 3.8 9.5e-22 76.9 3.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBY34819.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CBY34821.1 - 6.7e-22 77.4 3.8 9.5e-22 76.9 3.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBY34821.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Robl_LC7 PF03259.17 CBY34823.1 - 2.1e-25 88.3 0.0 2.3e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBY34823.1 - 2.6e-06 27.3 0.0 2.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 CBY34823.1 - 0.037 14.4 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain DUF223 PF02721.14 CBY34823.1 - 0.057 13.7 0.0 0.081 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF223 Ribosomal_L28e PF01778.17 CBY34824.1 - 2e-12 47.9 4.3 1.3e-11 45.2 4.3 1.9 1 1 0 1 1 1 1 Ribosomal L28e protein family DUF1944 PF09175.10 CBY34824.1 - 0.019 14.8 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Mito_carr PF00153.27 CBY34825.1 - 5.3e-56 186.5 2.3 5.5e-20 71.1 0.1 3.3 2 2 1 3 3 3 3 Mitochondrial carrier protein CbiM PF01891.16 CBY34825.1 - 0.0027 17.6 0.4 1.5 8.6 0.0 2.8 2 1 1 3 3 3 2 Cobalt uptake substrate-specific transmembrane region MMS1_N PF10433.9 CBY34826.1 - 1.7e-89 300.7 5.0 1.7e-89 300.7 1.7 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CBY34826.1 - 2.8e-68 230.6 1.0 6.6e-65 219.5 0.1 3.3 3 0 0 3 3 3 2 CPSF A subunit region DUF1923 PF09083.10 CBY34826.1 - 0.037 13.7 0.1 12 5.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1923) Ribosomal_L7Ae PF01248.26 CBY34827.1 - 1.5e-25 88.7 0.1 1.8e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBY34827.1 - 0.0026 17.8 0.1 0.0028 17.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CBY34827.1 - 0.0056 16.5 0.0 0.0073 16.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain TSP_1 PF00090.19 CBY34828.1 - 0.00065 19.9 9.9 0.00065 19.9 9.9 8.1 9 0 0 9 9 9 2 Thrombospondin type 1 domain DUF5052 PF16475.5 CBY34828.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) TFIIF_beta PF02270.15 CBY34829.1 - 1.6e-23 82.6 1.0 2.8e-23 81.8 1.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CBY34829.1 - 1.9e-10 41.6 1.2 6.5e-10 39.8 0.9 2.3 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus SIR4_SID PF16991.5 CBY34829.1 - 0.44 10.6 3.0 0.43 10.6 0.6 2.3 2 1 0 2 2 2 0 Sir4 SID domain RRM_1 PF00076.22 CBY34831.1 - 1.2e-18 66.7 0.1 2.5e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY34831.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY34831.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.19 CBY34832.1 - 6e-21 75.1 0.0 8.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBY34832.1 - 0.00018 22.0 0.2 0.0061 17.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY34832.1 - 0.0005 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY34832.1 - 0.00086 18.6 0.1 0.02 14.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CBY34832.1 - 0.0011 17.9 1.0 0.7 8.7 0.8 2.4 2 1 0 2 2 2 2 Tryptophan halogenase SE PF08491.10 CBY34832.1 - 0.0017 17.5 0.0 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 CBY34832.1 - 0.015 14.9 0.0 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 CBY34832.1 - 0.093 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CBY34832.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2935 PF11155.8 CBY34833.1 - 0.013 15.8 0.2 0.02 15.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) GrpE PF01025.19 CBY34833.1 - 0.027 14.1 2.2 0.044 13.4 2.2 1.3 1 0 0 1 1 1 0 GrpE Atg14 PF10186.9 CBY34833.1 - 0.082 12.0 1.3 0.079 12.0 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_lysis PF03245.13 CBY34833.1 - 0.16 12.1 4.6 0.29 11.2 4.6 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein EDR1 PF14381.6 CBY34834.1 - 1.9e-29 102.8 0.2 1.5e-28 99.9 0.0 2.2 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 CBY34834.1 - 1.2e-12 48.0 0.2 0.002 18.4 0.0 5.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 CBY34834.1 - 1.6e-11 43.4 4.1 0.56 10.6 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 CBY34834.1 - 3e-09 36.0 9.8 3.7e-06 25.8 0.2 2.4 2 1 0 2 2 2 2 Adaptin N terminal region Arm PF00514.23 CBY34834.1 - 3.6e-08 33.2 8.1 0.051 13.6 0.0 7.1 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBY34834.1 - 7e-07 29.4 5.8 0.00012 22.2 0.0 3.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CBY34834.1 - 1.6e-05 25.0 3.6 0.086 13.0 0.0 4.8 4 1 1 5 5 5 1 V-ATPase subunit H HEAT_EZ PF13513.6 CBY34834.1 - 0.00018 21.9 7.0 16 6.1 0.0 5.9 5 1 2 7 7 7 0 HEAT-like repeat Atx10homo_assoc PF09759.9 CBY34834.1 - 0.00024 21.1 0.3 0.89 9.6 0.0 4.0 2 1 2 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 CBY34834.1 - 0.00039 20.0 2.4 0.031 13.7 0.1 2.9 3 1 0 3 3 3 1 Armadillo-like Sec7_N PF12783.7 CBY34834.1 - 0.0084 16.0 5.1 5 7.0 0.8 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal NdhM PF10664.9 CBY34834.1 - 0.033 14.4 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M RTP1_C1 PF10363.9 CBY34834.1 - 0.2 11.9 0.7 4.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 C8 PF08742.11 CBY34835.1 - 1e-16 61.1 4.0 1e-16 61.1 4.0 2.0 2 0 0 2 2 2 1 C8 domain TIL PF01826.17 CBY34835.1 - 3.9e-09 36.6 16.4 3.9e-09 36.6 16.4 3.3 3 0 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain CENP-F_leu_zip PF10473.9 CBY34837.1 - 0.39 10.7 11.4 0.76 9.8 11.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.12 CBY34837.1 - 4 7.4 7.4 12 6.0 0.1 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Ion_trans PF00520.31 CBY34838.1 - 8.9e-07 28.4 0.7 1.3e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 CBY34838.1 - 0.24 10.1 2.3 0.36 9.4 2.3 1.2 1 0 0 1 1 1 0 Polycystin cation channel Herpes_US9 PF06072.11 CBY34838.1 - 0.53 10.2 2.0 1 9.3 1.1 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Kelch_6 PF13964.6 CBY34839.1 - 4.4e-05 23.6 1.9 0.72 10.2 0.0 3.9 3 1 1 4 4 4 2 Kelch motif HRI1 PF16815.5 CBY34839.1 - 0.0034 17.1 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein HRI1 Kelch_2 PF07646.15 CBY34839.1 - 0.005 16.8 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBY34839.1 - 0.008 15.7 3.1 0.44 10.2 0.0 3.9 4 1 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CBY34839.1 - 0.011 15.7 0.4 4.1 7.5 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 CBY34839.1 - 0.19 12.1 2.3 6.8 7.1 0.1 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY34840.1 - 0.074 13.4 2.5 11 6.5 0.4 3.2 1 1 1 2 2 2 0 Kelch motif Sulfotransfer_1 PF00685.27 CBY34841.1 - 5.5e-08 32.6 0.1 5.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY34841.1 - 6.5e-05 23.4 0.1 0.0021 18.5 0.0 2.3 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY34843.1 - 3.5e-18 66.4 1.0 5.4e-18 65.8 1.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Cadherin PF00028.17 CBY34844.1 - 1.2e-70 234.0 0.5 6.5e-14 52.2 0.0 7.2 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY34844.1 - 6.5e-10 38.7 0.1 9.1e-05 22.2 0.0 3.9 4 0 0 4 4 4 2 Cadherin-like Cadherin_3 PF16184.5 CBY34844.1 - 2.5e-07 30.7 5.5 0.12 12.4 0.2 6.3 6 1 0 6 6 6 2 Cadherin-like TMEM119 PF15724.5 CBY34844.1 - 0.044 13.9 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM119 family Pkinase PF00069.25 CBY34845.1 - 9.2e-09 35.0 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34845.1 - 6.9e-05 22.3 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SLATT_fungal PF18142.1 CBY34845.1 - 0.061 13.3 0.4 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Pkinase PF00069.25 CBY34846.1 - 2.2e-09 37.1 1.3 2.2e-09 37.1 1.3 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34846.1 - 7.3e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5403 PF17395.2 CBY34848.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5403) HemY_N PF07219.13 CBY34849.1 - 0.32 11.2 2.3 0.43 10.8 0.7 1.9 2 0 0 2 2 2 0 HemY protein N-terminus GAS PF13851.6 CBY34851.1 - 0.0028 17.0 5.4 0.0044 16.4 5.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Galactosyl_T PF01762.21 CBY34851.1 - 0.04 13.7 0.2 0.083 12.7 0.0 1.6 2 0 0 2 2 2 0 Galactosyltransferase Lectin_C PF00059.21 CBY34852.1 - 5e-06 27.2 9.8 0.0011 19.6 0.4 4.1 4 0 0 4 4 4 2 Lectin C-type domain Xlink PF00193.17 CBY34852.1 - 0.0053 17.1 4.6 2.8 8.4 0.1 4.2 3 1 1 4 4 4 2 Extracellular link domain UL45 PF05473.12 CBY34852.1 - 0.033 13.8 0.1 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like SNF PF00209.18 CBY34853.1 - 7.6e-201 668.3 28.9 8.8e-201 668.1 28.9 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GHMP_kinases_N PF00288.26 CBY34853.1 - 0.046 14.0 0.0 0.33 11.2 0.0 2.5 1 1 0 1 1 1 0 GHMP kinases N terminal domain DUF3533 PF12051.8 CBY34853.1 - 0.2 10.5 6.5 0.4 9.5 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FXa_inhibition PF14670.6 CBY34854.1 - 2.7e-06 27.5 5.8 5e-06 26.7 5.8 1.5 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY34854.1 - 0.0013 18.6 1.3 0.0029 17.5 1.3 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF PF00008.27 CBY34854.1 - 0.0028 17.9 3.2 0.0071 16.6 3.2 1.7 1 0 0 1 1 1 1 EGF-like domain TIL PF01826.17 CBY34854.1 - 0.05 13.9 4.7 0.088 13.1 4.7 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain EMC3_TMCO1 PF01956.16 CBY34854.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Galactosyl_T PF01762.21 CBY34855.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase B3_4 PF03483.17 CBY34855.1 - 0.081 12.6 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 B3/4 domain Tektin PF03148.14 CBY34856.1 - 8.4e-102 340.8 20.4 9.4e-102 340.6 20.4 1.0 1 0 0 1 1 1 1 Tektin family 5_3_exonuc PF01367.20 CBY34856.1 - 0.098 13.3 1.4 1.4 9.6 0.0 3.1 3 1 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Syntaxin-6_N PF09177.11 CBY34856.1 - 0.42 11.2 16.8 0.056 14.0 2.4 4.1 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF4472 PF14739.6 CBY34856.1 - 0.66 10.7 13.5 2.3 9.0 2.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4472) Golgin_A5 PF09787.9 CBY34856.1 - 1.1 8.7 16.3 5.5 6.4 5.6 3.6 2 2 2 4 4 4 0 Golgin subfamily A member 5 zf-C4H2 PF10146.9 CBY34856.1 - 1.6 8.9 11.3 0.076 13.3 3.2 2.6 2 1 1 3 3 3 0 Zinc finger-containing protein FAM184 PF15665.5 CBY34856.1 - 2.4 7.9 14.1 2.2 8.0 6.3 3.0 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B End3 PF12761.7 CBY34856.1 - 3.8 7.6 11.2 0.79 9.9 2.3 3.3 2 1 2 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 AAA_11 PF13086.6 CBY34856.1 - 3.9 7.2 6.8 19 4.9 6.7 2.0 1 1 0 1 1 1 0 AAA domain YojJ PF10372.9 CBY34856.1 - 4.5 7.4 7.6 33 4.7 0.2 3.8 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus BSD PF03909.17 CBY34857.1 - 4e-15 55.6 7.5 7.8e-15 54.6 0.1 3.3 3 0 0 3 3 3 1 BSD domain SLATT_fungal PF18142.1 CBY34857.1 - 0.27 11.2 1.4 22 5.1 0.0 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Focal_AT PF03623.13 CBY34857.1 - 7.8 6.5 11.6 1.8 8.6 1.6 3.1 2 1 1 3 3 3 0 Focal adhesion targeting region Kelch_1 PF01344.25 CBY34858.1 - 2.6e-45 151.8 7.7 2.1e-12 46.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY34858.1 - 8.2e-33 111.6 6.0 2.3e-10 40.4 0.0 7.2 2 2 4 6 6 6 6 Kelch motif BTB PF00651.31 CBY34858.1 - 7.7e-26 90.5 0.2 7.7e-26 90.5 0.2 2.1 3 0 0 3 3 3 1 BTB/POZ domain Kelch_2 PF07646.15 CBY34858.1 - 8.6e-21 73.1 9.1 9e-05 22.3 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBY34858.1 - 7.2e-19 67.6 1.8 1.7e-06 28.2 0.0 6.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY34858.1 - 6.2e-16 58.1 5.9 1e-05 25.4 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY34858.1 - 8.3e-14 51.2 7.7 0.021 14.8 0.0 6.0 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 CBY34858.1 - 3.6e-12 46.3 0.1 9.7e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch Ank_4 PF13637.6 CBY34859.1 - 1.7e-06 28.4 0.0 0.00028 21.4 0.0 2.6 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY34859.1 - 2.6e-05 24.5 0.0 0.0055 17.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBY34859.1 - 0.00037 21.0 0.1 0.0015 19.1 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY34859.1 - 0.0048 17.2 0.0 0.044 14.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF1211 PF06736.11 CBY34859.1 - 0.033 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) bZIP_1 PF00170.21 CBY34860.1 - 0.00028 20.9 3.1 0.00028 20.9 3.1 1.5 1 1 1 2 2 2 1 bZIP transcription factor ZapB PF06005.12 CBY34860.1 - 0.0019 18.6 1.2 0.0024 18.3 1.2 1.2 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 CBY34860.1 - 0.0049 16.6 1.4 0.007 16.1 1.4 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF1474 PF07342.11 CBY34860.1 - 0.015 15.8 0.6 0.018 15.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) NRBF2 PF08961.10 CBY34860.1 - 0.032 13.9 1.7 0.044 13.4 1.7 1.4 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Tfb4 PF03850.14 CBY34860.1 - 0.035 13.6 0.2 0.036 13.6 0.2 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 PRKG1_interact PF15898.5 CBY34860.1 - 0.037 14.9 5.4 2.3 9.2 1.2 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Arb2 PF09757.9 CBY34860.1 - 0.042 13.0 0.3 0.046 12.8 0.3 1.0 1 0 0 1 1 1 0 Arb2 domain T4bSS_IcmS PF12608.8 CBY34860.1 - 0.075 13.4 0.4 0.085 13.2 0.4 1.1 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment APG6_N PF17675.1 CBY34860.1 - 0.16 12.5 5.9 0.3 11.6 5.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Aldo_ket_red PF00248.21 CBY34862.1 - 1.2e-52 179.0 0.0 1.7e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Haspin_kinase PF12330.8 CBY34862.1 - 0.031 13.2 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 CBY34863.1 - 2.7e-13 50.3 0.0 2.4e-05 24.8 0.0 2.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY34863.1 - 1.2e-11 44.9 0.0 0.0017 18.9 0.0 4.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY34863.1 - 3.6e-07 30.0 0.0 0.22 12.2 0.0 4.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CBY34863.1 - 1.3e-05 25.3 0.6 0.012 15.9 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY34863.1 - 0.00093 19.5 0.0 0.71 10.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat FAM53 PF15242.6 CBY34863.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of FAM53 Ank_3 PF13606.6 CBY34865.1 - 0.0001 22.4 0.3 0.00025 21.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY34865.1 - 0.0066 16.7 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY34865.1 - 0.12 12.9 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat WD40 PF00400.32 CBY34866.1 - 9.3e-35 118.1 19.3 8.1e-09 36.0 1.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY34866.1 - 0.0023 18.2 1.4 9 6.7 0.2 4.4 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY34866.1 - 0.037 12.7 1.9 7.6 5.0 0.4 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 AAA PF00004.29 CBY34867.1 - 1.3e-39 135.7 0.0 3.2e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 CBY34867.1 - 8.9e-33 113.7 0.6 2.3e-32 112.4 0.6 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CBY34867.1 - 3.6e-13 49.1 0.1 2.5e-12 46.4 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CBY34867.1 - 8.2e-06 26.3 0.6 0.0022 18.4 0.0 3.3 3 1 1 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 CBY34867.1 - 1e-05 25.7 0.0 9.3e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY34867.1 - 1.2e-05 25.3 0.1 0.00019 21.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY34867.1 - 6.8e-05 22.7 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBY34867.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 CBY34867.1 - 0.00088 19.5 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY34867.1 - 0.001 19.4 0.1 0.012 15.9 0.1 2.6 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 CBY34867.1 - 0.0013 17.9 0.0 0.0033 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CBY34867.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CBY34867.1 - 0.0018 17.6 1.6 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBY34867.1 - 0.0024 17.3 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBY34867.1 - 0.0031 18.0 5.1 0.0034 17.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CBY34867.1 - 0.0072 16.7 0.0 0.029 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBY34867.1 - 0.016 15.2 0.0 0.082 12.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 CBY34867.1 - 0.017 15.2 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBY34867.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBY34867.1 - 0.045 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Spore_permease PF03845.13 CBY34867.1 - 0.05 12.4 0.1 0.083 11.7 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein AAA_17 PF13207.6 CBY34867.1 - 0.055 13.9 0.0 0.055 13.9 0.0 2.6 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.22 CBY34867.1 - 0.067 13.6 0.0 0.25 11.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBY34867.1 - 0.071 12.8 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBY34867.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.7 3 1 0 3 3 2 0 AAA domain POP1 PF06978.11 CBY34867.1 - 0.45 10.5 6.6 0.078 13.0 2.1 2.0 2 0 0 2 2 1 0 Ribonucleases P/MRP protein subunit POP1 HJURP_mid PF12346.8 CBY34867.1 - 0.92 10.0 4.2 2.3 8.7 4.2 1.6 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat AAA_11 PF13086.6 CBY34867.1 - 1 9.1 0.0 1 9.1 0.0 2.8 3 1 0 3 3 3 0 AAA domain CH PF00307.31 CBY34869.1 - 4.8e-81 268.1 0.0 2.1e-24 85.8 0.2 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY34869.1 - 6.3e-10 38.8 0.1 0.00013 21.7 0.1 3.7 4 0 0 4 4 4 3 CAMSAP CH domain p450 PF00067.22 CBY34871.1 - 6.3e-58 196.6 0.2 1.1e-57 195.9 0.2 1.3 1 0 0 1 1 1 1 Cytochrome P450 PLDc PF00614.22 CBY34873.1 - 1.1e-17 63.4 0.3 8.3e-08 32.1 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CBY34873.1 - 2.2e-17 63.2 0.1 1.1e-07 31.8 0.1 3.3 2 1 0 2 2 2 2 PLD-like domain mTERF PF02536.14 CBY34873.1 - 6.7e-12 45.0 0.4 1.4e-11 44.0 0.4 1.6 1 1 0 1 1 1 1 mTERF DASH_Ask1 PF08655.10 CBY34873.1 - 0.096 12.6 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Ask1 Branch PF02485.21 CBY34874.1 - 5.4e-06 26.1 0.0 7.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme LRR_4 PF12799.7 CBY34875.1 - 4.7e-42 141.3 62.2 1.6e-08 34.7 3.7 6.8 2 1 10 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY34875.1 - 3.1e-21 75.7 22.1 1.2e-09 37.9 3.5 4.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.6 CBY34875.1 - 2e-17 62.7 26.5 7.2e-08 32.1 4.5 6.5 4 2 2 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 CBY34875.1 - 0.00018 21.3 20.4 0.36 11.0 0.3 7.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CBY34875.1 - 0.023 15.2 25.3 5.7 7.9 0.9 8.7 8 2 1 9 9 9 0 Leucine Rich Repeat DUF2322 PF10084.9 CBY34875.1 - 0.083 12.9 4.0 1.7 8.8 0.1 3.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) UB2H PF14814.6 CBY34875.1 - 0.17 11.9 0.5 44 4.2 0.0 3.6 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain MIP-T3 PF10243.9 CBY34876.1 - 2.2e-42 143.6 0.9 2.2e-42 143.6 0.9 3.3 2 2 1 3 3 3 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 CBY34876.1 - 5.2e-17 62.2 13.5 5.2e-17 62.2 13.5 3.8 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region MeaB PF03308.16 CBY34877.1 - 4.8e-85 284.8 0.0 5.4e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CBY34877.1 - 0.00015 21.6 0.1 0.00046 20.0 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY34877.1 - 0.0018 17.9 0.1 0.0072 15.9 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBY34877.1 - 0.0028 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY34877.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBY34877.1 - 0.019 15.5 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CBY34877.1 - 0.025 15.1 1.1 0.053 14.1 0.1 2.1 3 0 0 3 3 3 0 AAA domain CitG PF01874.16 CBY34877.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 1 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase AAA_29 PF13555.6 CBY34877.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CBY34877.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CBY34877.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 CBY34877.1 - 0.065 13.3 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CBY34877.1 - 0.079 13.0 0.5 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 CBY34877.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 CBY34877.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 CBY34877.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_19 PF13245.6 CBY34877.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pox_H7 PF04787.12 CBY34878.1 - 0.019 15.5 2.5 0.028 15.0 2.1 1.5 1 1 0 1 1 1 0 Late protein H7 Spc29 PF17082.5 CBY34878.1 - 0.02 14.7 9.0 0.069 13.0 4.4 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF3810 PF12725.7 CBY34878.1 - 0.035 13.5 1.3 0.049 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SlyX PF04102.12 CBY34878.1 - 7.4 7.3 9.2 24 5.6 9.2 1.8 1 1 0 1 1 1 0 SlyX PDZ PF00595.24 CBY34879.1 - 1.5e-10 41.3 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY34879.1 - 6.8e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY34879.1 - 3.1e-06 27.4 0.0 8.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF444 PF04285.12 CBY34879.1 - 0.75 8.8 5.4 0.17 10.9 2.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF444) UBA2_C PF16195.5 CBY34879.1 - 8.7 7.1 13.1 12 6.7 7.2 2.5 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Pribosyltran PF00156.27 CBY34880.1 - 1.5e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBY34880.1 - 0.0057 16.1 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBY34880.1 - 0.03 13.8 0.1 0.066 12.7 0.1 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase AMP-binding PF00501.28 CBY34881.1 - 5.2e-97 325.1 0.0 7.1e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY34881.1 - 0.066 14.2 0.3 0.29 12.1 0.3 2.2 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CBY34882.1 - 7.4e-61 205.8 0.0 1.2e-60 205.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34882.1 - 4.6e-33 114.6 0.0 6.9e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CSL PF05207.13 CBY34882.1 - 3.9e-23 80.9 4.6 8.2e-22 76.7 2.0 2.6 2 0 0 2 2 2 1 CSL zinc finger Kinase-like PF14531.6 CBY34882.1 - 4.9e-07 29.3 0.0 9.9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY34882.1 - 0.00036 20.5 0.0 0.00089 19.2 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY34882.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY34882.1 - 0.0087 15.7 0.0 0.026 14.1 0.0 1.7 1 1 1 2 2 2 1 RIO1 family Zn-ribbon_8 PF09723.10 CBY34882.1 - 0.01 16.0 4.1 0.033 14.3 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain KA1 PF02149.19 CBY34882.1 - 0.07 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 RhoGEF PF00621.20 CBY34883.1 - 7.5e-17 62.1 10.6 1.4e-10 41.7 1.4 3.1 2 1 1 3 3 3 2 RhoGEF domain Syntaxin-6_N PF09177.11 CBY34883.1 - 0.13 12.9 7.6 1.6 9.3 0.0 3.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal ETRAMP PF09716.10 CBY34883.1 - 2.9 8.0 0.0 2.9 8.0 0.0 3.5 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1947 PF09183.10 CBY34883.1 - 9.2 6.6 7.7 8.5 6.8 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) DUF908 PF06012.12 CBY34884.1 - 0.29 10.5 6.4 0.39 10.1 6.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) AAA_11 PF13086.6 CBY34884.1 - 0.37 10.5 12.2 0.52 10.1 12.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3381 PF11861.8 CBY34884.1 - 0.42 10.4 20.5 0.71 9.7 20.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Borrelia_P83 PF05262.11 CBY34884.1 - 0.84 8.1 18.4 1.1 7.7 18.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IHABP4_N PF16174.5 CBY34884.1 - 0.95 10.0 19.7 2.1 9.0 19.7 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3807 PF12720.7 CBY34884.1 - 1.1 9.6 14.3 1.8 8.8 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Zip PF02535.22 CBY34884.1 - 3.9 6.6 4.2 5.2 6.2 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 CBY34884.1 - 5 7.1 5.7 7 6.6 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FancD2 PF14631.6 CBY34884.1 - 6.1 4.1 8.5 7.7 3.8 8.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RNase_T PF00929.24 CBY34885.1 - 0.00018 22.1 0.3 0.00069 20.2 0.0 2.1 2 1 0 2 2 2 1 Exonuclease PCNA_C PF02747.15 CBY34886.1 - 9.1e-53 177.8 0.0 1.9e-52 176.8 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 CBY34886.1 - 4.7e-47 158.9 2.0 7.1e-47 158.3 2.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 CBY34886.1 - 0.0016 17.9 0.0 0.0022 17.5 0.0 1.3 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 CBY34886.1 - 0.042 12.9 0.0 0.062 12.4 0.0 1.5 1 1 0 1 1 1 0 Hus1-like protein Homeodomain PF00046.29 CBY34887.1 - 8.2e-22 76.8 7.1 1.5e-21 76.0 7.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY34887.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.3 3 0 0 3 3 3 0 Homeobox KN domain Mucin PF01456.17 CBY34888.1 - 8.5e-05 22.6 28.6 0.00012 22.1 28.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF5401 PF17380.2 CBY34888.1 - 0.067 11.3 2.5 0.082 11.0 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FNIP_N PF14636.6 CBY34888.1 - 0.76 10.7 4.4 1.2 10.1 4.4 1.4 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Dicty_REP PF05086.12 CBY34888.1 - 0.83 7.6 11.6 1.3 6.9 11.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 CBY34888.1 - 1.4 7.0 10.1 1.6 6.8 10.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SecE PF00584.20 CBY34890.1 - 0.1 12.6 1.4 0.17 11.8 1.4 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Na_Ca_ex PF01699.24 CBY34891.1 - 1.6e-40 138.5 37.0 6.7e-23 81.3 11.5 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein CUB PF00431.20 CBY34892.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CUB domain ITI_HC_C PF06668.12 CBY34893.1 - 0.0066 16.1 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus S-AdoMet_synt_N PF00438.20 CBY34894.1 - 7.9e-43 145.2 0.1 9.3e-43 144.9 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CBY34894.1 - 0.016 14.1 0.3 0.022 13.6 0.3 1.3 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Cg6151-P PF10233.9 CBY34896.1 - 1.7e-14 54.1 11.7 2e-14 53.9 11.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 CBY34896.1 - 0.0014 18.4 1.9 0.0018 18.0 1.9 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 PRA1 PF03208.19 CBY34896.1 - 0.96 9.1 5.4 1.3 8.6 5.4 1.2 1 0 0 1 1 1 0 PRA1 family protein COPI_assoc PF08507.10 CBY34896.1 - 2 8.5 11.8 2.8 8.0 11.8 1.4 1 1 0 1 1 1 0 COPI associated protein SseC PF04888.12 CBY34896.1 - 4.2 6.9 11.8 0.61 9.6 1.6 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF2628 PF10947.8 CBY34896.1 - 9.3 6.7 6.7 1.7 9.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) TPR_19 PF14559.6 CBY34897.1 - 0.0013 19.2 0.3 0.061 13.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY34897.1 - 0.0036 18.0 0.1 54 5.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY34897.1 - 3.6 8.0 10.6 85 3.6 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SANTA PF09133.10 CBY34899.1 - 1.4e-05 25.5 0.5 5.1e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 SANTA (SANT Associated) zf-C3HC4_4 PF15227.6 CBY34900.1 - 9.6e-05 22.5 15.7 0.00017 21.7 15.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY34900.1 - 0.00012 21.9 12.9 0.00019 21.2 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY34900.1 - 0.00058 19.7 16.4 0.0012 18.7 16.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY34900.1 - 0.013 15.8 14.6 0.032 14.6 14.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CBY34900.1 - 0.016 15.3 13.1 0.031 14.3 13.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBY34900.1 - 0.041 13.9 15.7 0.089 12.8 15.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 CBY34900.1 - 0.23 11.4 11.3 0.66 9.9 11.4 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CBY34900.1 - 2 8.3 17.1 9.5 6.2 17.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY34900.1 - 2.4 8.1 15.1 5.5 6.9 15.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cation_ATPase_C PF00689.21 CBY34901.1 - 3e-19 69.5 0.1 3.3e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF1290 PF06947.12 CBY34901.1 - 0.0058 16.7 0.1 0.0086 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) Cation_ATPase PF13246.6 CBY34902.1 - 1.3e-22 79.7 0.0 2.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY34902.1 - 1.3e-21 77.9 0.4 5e-21 76.0 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY34902.1 - 5.1e-18 65.2 1.1 5.1e-18 65.2 1.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY34902.1 - 1.2e-11 44.6 0.0 1.2e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CBY34902.1 - 1.9e-07 31.1 0.6 0.00032 20.5 0.6 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY34902.1 - 0.0043 17.5 0.1 0.0097 16.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TFIIE_beta PF02186.15 CBY34902.1 - 0.27 11.6 0.6 0.65 10.3 0.1 1.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain Peripla_BP_4 PF13407.6 CBY34902.1 - 1.7 8.2 6.8 3 7.4 0.3 3.2 4 0 0 4 4 4 0 Periplasmic binding protein domain GATA PF00320.27 CBY34903.1 - 2.7e-25 87.7 21.4 9.2e-13 47.6 7.6 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY34903.1 - 4e-07 29.4 7.2 0.00075 19.0 1.6 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.13 CBY34903.1 - 0.14 12.2 8.5 0.8 9.8 1.6 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.10 CBY34903.1 - 0.6 9.9 6.5 0.32 10.8 0.4 2.9 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 CBY34903.1 - 0.71 10.0 5.6 4.3 7.5 0.2 2.9 2 1 1 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 CBY34903.1 - 1.4 8.8 7.8 3.8 7.4 2.3 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 CBY34903.1 - 1.7 8.8 9.8 1.9 8.7 0.5 2.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prim_Zn_Ribbon PF08273.12 CBY34903.1 - 2.1 8.7 4.5 33 4.9 1.0 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Helicase_C PF00271.31 CBY34905.1 - 3.8e-14 53.0 0.0 1.9e-13 50.7 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY34905.1 - 2.7e-11 43.6 0.0 1.2e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 CBY34905.1 - 2e-08 34.0 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 CBY34905.1 - 9.1e-07 29.5 0.4 2.7e-06 28.0 0.4 1.8 1 0 0 1 1 1 1 RecQ zinc-binding adh_short_C2 PF13561.6 CBY34907.1 - 1.1e-55 188.8 0.2 1.5e-55 188.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY34907.1 - 5.5e-54 182.6 0.7 8e-54 182.1 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY34907.1 - 5.6e-12 45.9 0.1 8.1e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Shisa PF13908.6 CBY34908.1 - 0.0036 17.6 2.0 0.0076 16.5 0.0 2.5 3 1 0 3 3 3 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 CBY34908.1 - 0.13 12.3 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 MAP17 PF15807.5 CBY34908.1 - 3.8 7.8 5.5 4.4 7.6 0.0 2.7 1 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 CBY34908.1 - 8.4 7.4 8.1 2.9e+02 2.5 7.9 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Herpes_DNAp_acc PF04929.12 CBY34908.1 - 9.7 5.1 11.8 21 4.0 11.8 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Trypsin PF00089.26 CBY34909.1 - 2.2e-54 184.6 0.0 3.1e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY34909.1 - 4.4e-07 30.1 2.3 5.7e-06 26.6 2.3 2.7 1 1 0 1 1 1 1 Kringle domain Trypsin_2 PF13365.6 CBY34909.1 - 1.4e-05 26.0 0.0 2.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY34909.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Peptidase_C3 PF00548.20 CBY34909.1 - 2.3 8.1 3.8 89 2.9 0.0 3.0 3 0 0 3 3 3 0 3C cysteine protease (picornain 3C) Gp_dh_C PF02800.20 CBY34910.1 - 3.4e-59 199.0 0.3 5.3e-59 198.3 0.3 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY34910.1 - 5e-34 116.7 0.1 1.1e-33 115.6 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY34910.1 - 0.00093 19.3 2.7 0.021 14.9 0.5 3.4 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus ACT_4 PF13291.6 CBY34910.1 - 0.021 15.4 0.0 0.062 13.9 0.0 1.8 1 0 0 1 1 1 0 ACT domain FDX-ACB PF03147.14 CBY34910.1 - 0.085 13.3 0.3 0.3 11.5 0.2 1.9 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain 2-Hacid_dh_C PF02826.19 CBY34910.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase_2 PF01112.18 CBY34911.1 - 4.9e-80 268.8 7.1 6.1e-80 268.5 7.1 1.0 1 0 0 1 1 1 1 Asparaginase Neur_chan_LBD PF02931.23 CBY34912.1 - 9e-46 156.0 4.0 1.2e-45 155.6 4.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY34912.1 - 7.4e-16 58.9 5.4 1e-15 58.4 5.4 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4131 PF13567.6 CBY34912.1 - 0.31 10.7 1.0 0.55 9.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AdenylateSensor PF16579.5 CBY34913.1 - 5.5e-13 49.4 0.1 9.2e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase EF-hand_1 PF00036.32 CBY34915.1 - 1.1e-14 52.8 1.7 1.3e-06 27.6 0.5 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY34915.1 - 6.2e-13 47.5 1.0 7.5e-06 25.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY34915.1 - 5.8e-12 44.5 2.9 1.1e-05 24.6 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY34915.1 - 1.8e-09 37.9 0.2 2.1e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY34915.1 - 1.8e-08 34.1 0.6 0.00033 20.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 CBY34915.1 - 0.00054 19.9 0.2 0.23 11.4 0.1 2.0 1 1 1 2 2 2 2 Caleosin related protein EF-hand_10 PF14788.6 CBY34915.1 - 0.0023 17.8 0.7 0.0065 16.3 0.4 1.8 1 1 1 2 2 2 1 EF hand DUF294_C PF10335.9 CBY34915.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain NAD_synthase PF02540.17 CBY34915.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 NAD synthase Arg_decarbox_C PF17944.1 CBY34915.1 - 0.12 13.0 0.4 11 6.7 0.1 2.2 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension zf-MYND PF01753.18 CBY34918.1 - 0.015 15.3 7.5 0.96 9.6 1.1 3.1 3 0 0 3 3 3 0 MYND finger TGF_beta PF00019.20 CBY34918.1 - 0.021 15.8 1.0 0.11 13.5 0.7 2.1 1 1 0 1 1 1 0 Transforming growth factor beta like domain zf-RING_2 PF13639.6 CBY34919.1 - 9.3e-10 38.7 5.2 1.5e-09 38.0 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY34919.1 - 3.9e-08 33.0 5.3 7.9e-08 32.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY34919.1 - 4.2e-07 29.7 6.7 7.3e-07 29.0 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY34919.1 - 1.3e-06 28.2 7.3 2e-06 27.6 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY34919.1 - 3.9e-06 26.8 3.0 7.6e-06 25.9 3.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY34919.1 - 1.1e-05 25.6 5.7 2.2e-05 24.6 5.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY34919.1 - 2.5e-05 24.0 3.3 4.2e-05 23.3 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY34919.1 - 0.0043 16.9 4.1 0.0074 16.1 3.8 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C4H2 PF10146.9 CBY34919.1 - 0.0045 17.3 3.8 0.0072 16.7 3.8 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein zf-RING_4 PF14570.6 CBY34919.1 - 0.0077 16.0 5.6 0.015 15.1 5.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBY34919.1 - 0.013 15.2 2.3 0.028 14.2 2.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF3584 PF12128.8 CBY34919.1 - 0.023 12.3 3.3 0.028 11.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CHDCT2 PF08074.11 CBY34919.1 - 0.069 13.3 1.1 0.096 12.9 1.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF3662 PF12401.8 CBY34919.1 - 0.09 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF1272 PF06906.11 CBY34919.1 - 0.33 11.1 4.1 0.59 10.3 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 CBY34919.1 - 0.5 10.6 6.5 2 8.7 6.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF16 PF01519.16 CBY34919.1 - 1.2 9.7 7.9 6.9 7.2 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 zf-RING_10 PF16685.5 CBY34919.1 - 1.3 9.2 7.0 5.4 7.2 6.6 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING-like PF08746.11 CBY34919.1 - 5.7 7.3 8.6 19 5.7 8.6 1.8 1 1 0 1 1 1 0 RING-like domain Homeodomain PF00046.29 CBY34920.1 - 9.1e-22 76.7 6.2 2e-21 75.6 6.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY34920.1 - 0.0025 17.7 0.1 0.0098 15.8 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Glyco_hydro_63 PF03200.16 CBY34922.1 - 4.9e-191 635.8 0.4 6.4e-191 635.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CBY34922.1 - 1.9e-32 113.2 2.9 4.2e-32 112.1 2.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CBY34922.1 - 0.0018 17.3 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Pkinase PF00069.25 CBY34923.1 - 1e-31 110.3 0.0 3.8e-23 82.2 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY34923.1 - 4.4e-14 52.4 0.0 1.4e-11 44.2 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBY34923.1 - 0.0023 17.9 0.3 0.0042 17.0 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Apt1 PF10351.9 CBY34923.1 - 0.094 11.6 7.6 0.12 11.2 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1681 PF07933.14 CBY34924.1 - 1.5e-51 174.0 0.0 1.8e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) E1_dh PF00676.20 CBY34925.1 - 3.6e-25 88.5 0.0 4.6e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component RTBV_P12 PF06361.11 CBY34928.1 - 0.048 14.1 0.3 0.089 13.2 0.3 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Homeobox_KN PF05920.11 CBY34929.1 - 1.7e-06 27.8 0.9 1.7e-06 27.8 0.9 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBY34929.1 - 0.0085 15.9 1.1 0.017 15.0 1.1 1.5 1 0 0 1 1 1 1 Homeodomain TSP9 PF11493.8 CBY34930.1 - 3.7 8.3 8.1 1.7 9.3 0.1 3.3 1 1 3 4 4 4 0 Thylakoid soluble phosphoprotein TSP9 EF-hand_1 PF00036.32 CBY34931.1 - 7.3e-20 69.0 8.6 1.2e-05 24.5 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY34931.1 - 1.1e-19 68.6 7.9 8.3e-05 22.2 1.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY34931.1 - 3.9e-17 62.5 8.8 2.9e-09 37.2 3.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY34931.1 - 6.8e-13 47.5 6.4 0.0029 17.0 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY34931.1 - 2.6e-12 46.4 9.4 8.9e-10 38.3 1.8 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBY34931.1 - 0.02 14.8 3.8 0.15 12.0 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Prok_Ub PF14454.6 CBY34931.1 - 0.04 13.6 0.1 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic Ubiquitin EF-hand_9 PF14658.6 CBY34931.1 - 2.5 8.5 5.9 6.7 7.1 0.3 3.4 3 2 0 3 3 3 0 EF-hand domain PTPRCAP PF15713.5 CBY34932.1 - 0.082 13.2 1.9 0.14 12.4 1.9 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mem_trans PF03547.18 CBY34932.1 - 0.13 10.7 0.9 0.13 10.6 0.9 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 CBY34932.1 - 0.56 8.4 10.0 0.032 12.5 4.8 1.5 2 0 0 2 2 2 0 CDC45-like protein NAD_binding_3 PF03447.16 CBY34933.1 - 1.3e-06 29.1 0.0 1.8e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF108 PF01958.18 CBY34935.1 - 8.1e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF108 Evf PF18270.1 CBY34935.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Virulence factor Evf RRM_1 PF00076.22 CBY34936.1 - 4.9e-10 39.1 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY34936.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CBY34936.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RR_TM4-6 PF06459.12 CBY34936.1 - 4.3 7.1 13.1 8.4 6.1 13.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IRF-2BP1_2 PF11261.8 CBY34938.1 - 2.3e-14 52.7 1.0 6.4e-14 51.3 0.4 2.2 2 0 0 2 2 2 1 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4_2 PF13923.6 CBY34938.1 - 0.086 12.7 6.5 0.25 11.2 6.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) B56 PF01603.20 CBY34939.1 - 6.8e-103 344.8 4.5 8.8e-103 344.4 4.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RteC PF09357.10 CBY34939.1 - 0.051 13.3 0.4 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 RteC protein Sec7_N PF12783.7 CBY34939.1 - 0.053 13.4 2.3 1.7 8.6 0.0 2.7 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Telomere_reg-2 PF10193.9 CBY34939.1 - 0.12 12.8 0.0 6.1 7.3 0.0 3.2 4 0 0 4 4 4 0 Telomere length regulation protein YdjC PF04794.12 CBY34940.1 - 1.4e-18 67.8 0.0 1.8e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 YdjC-like protein CvfB_WH PF17783.1 CBY34940.1 - 0.12 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 CvfB-like winged helix domain 5_nucleotid PF05761.14 CBY34941.1 - 1.9e-122 409.5 0.2 2.2e-122 409.3 0.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family Methyltransf_15 PF09445.10 CBY34942.1 - 6.9e-41 139.6 0.0 1.2e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 CBY34942.1 - 9.8e-09 35.2 0.1 4.6e-07 29.8 0.0 2.3 1 1 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CBY34942.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY34942.1 - 3.2e-06 27.8 0.0 7.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CBY34942.1 - 8.9e-06 25.5 0.1 6.9e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 CBY34942.1 - 0.00017 21.3 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CBY34942.1 - 0.00034 21.2 0.0 0.00091 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY34942.1 - 0.00072 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 CBY34942.1 - 0.00097 18.4 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 CBY34942.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CBY34942.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CBY34942.1 - 0.042 13.0 0.0 0.073 12.2 0.0 1.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase UDPG_MGDP_dh_N PF03721.14 CBY34942.1 - 0.052 13.1 1.0 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 CBY34942.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cupin_8 PF13621.6 CBY34942.1 - 0.095 12.4 1.6 3 7.5 1.0 2.2 2 1 0 2 2 2 0 Cupin-like domain Exo_endo_phos PF03372.23 CBY34943.1 - 2.1e-12 47.0 0.0 6.4e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBP_BcsN PF17038.5 CBY34944.1 - 0.053 12.9 0.1 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsN BNIP3 PF06553.12 CBY34947.1 - 0.038 13.7 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 BNIP3 Yos9_DD PF17880.1 CBY34947.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Yos9 dimerzation domain DUF1325 PF07039.11 CBY34948.1 - 3.3e-30 104.9 0.0 6.5e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_2 PF18104.1 CBY34948.1 - 0.03 14.0 0.1 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 CBY34948.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 CBY34948.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 CBY34948.1 - 0.079 12.7 0.2 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 PRD PF00874.20 CBY34948.1 - 0.11 12.8 1.3 0.18 12.1 1.3 1.4 1 0 0 1 1 1 0 PRD domain DUF4618 PF15397.6 CBY34948.1 - 0.16 11.4 4.8 0.21 11.0 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Chromo PF00385.24 CBY34949.1 - 7.9e-15 54.5 2.8 3.1e-14 52.6 2.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY34949.1 - 0.0015 18.6 2.5 0.0058 16.7 0.0 3.0 4 0 0 4 4 4 1 Chromo shadow domain VWA PF00092.28 CBY34949.1 - 0.0024 18.1 2.4 0.57 10.4 0.6 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain Abhydrolase_5 PF12695.7 CBY34949.1 - 0.041 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family EGF_2 PF07974.13 CBY34949.1 - 0.59 10.5 6.7 0.1 13.0 1.4 2.4 2 0 0 2 2 2 0 EGF-like domain Homeodomain PF00046.29 CBY34950.1 - 2.8e-22 78.3 4.3 6.9e-22 77.1 4.3 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY34950.1 - 0.022 14.6 0.2 0.022 14.6 0.2 2.6 3 0 0 3 3 3 0 Homeobox KN domain DUF4685 PF15737.5 CBY34950.1 - 0.054 13.9 6.1 0.065 13.7 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Homez PF11569.8 CBY34950.1 - 0.062 12.8 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Spt20 PF12090.8 CBY34950.1 - 0.74 9.4 10.9 16 5.0 8.4 2.3 2 0 0 2 2 2 0 Spt20 family DUF3138 PF11336.8 CBY34950.1 - 5.5 5.5 10.8 8.4 4.9 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PLAC8 PF04749.17 CBY34952.1 - 1e-17 64.9 15.1 2e-17 64.0 15.1 1.4 1 1 0 1 1 1 1 PLAC8 family DnaI_N PF07319.11 CBY34953.1 - 0.0086 16.7 0.2 0.09 13.5 0.1 2.9 1 1 0 1 1 1 1 Primosomal protein DnaI N-terminus Choline_kinase PF01633.20 CBY34955.1 - 1.1e-42 146.0 0.0 2.3e-42 145.0 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY34955.1 - 1.9e-06 28.0 0.0 4.8e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY34955.1 - 0.0005 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Rhomboid PF01694.22 CBY34957.1 - 6.2e-31 107.4 13.9 6.2e-31 107.4 13.9 1.7 2 0 0 2 2 2 1 Rhomboid family YWFCY PF14293.6 CBY34957.1 - 1.3 9.3 5.4 8.6 6.7 0.2 3.3 3 1 1 4 4 4 0 YWFCY protein Cytochrom_B561 PF03188.16 CBY34957.1 - 6.2 7.0 10.6 1.5 8.9 1.2 2.3 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 PI3K_1B_p101 PF10486.9 CBY34959.1 - 0.03 12.1 3.5 0.03 12.1 3.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4994 PF16385.5 CBY34959.1 - 0.048 13.6 0.1 0.29 11.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function Sulfotransfer_1 PF00685.27 CBY34960.1 - 3.2e-05 23.5 0.1 4.3e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY34960.1 - 0.18 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Tox-PLDMTX PF15645.6 CBY34961.1 - 0.025 14.9 1.4 0.11 12.7 0.2 1.9 1 1 1 2 2 2 0 Dermonecrotoxin of the Papain-like fold NRDE-2 PF08424.10 CBY34961.1 - 0.032 13.3 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF5106 PF17127.4 CBY34961.1 - 0.11 12.8 0.4 0.18 12.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5106) MIP PF00230.20 CBY34962.1 - 1e-16 61.3 1.1 1.3e-16 61.0 1.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Polysacc_synt_C PF14667.6 CBY34962.1 - 0.037 14.1 1.8 0.049 13.7 1.8 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.6 CBY34962.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Mito_carr PF00153.27 CBY34963.1 - 2.8e-63 209.9 7.0 2.4e-24 85.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBY34963.1 - 0.1 11.8 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Fuseless 5-FTHF_cyc-lig PF01812.20 CBY34964.1 - 3.9e-18 66.0 0.0 4.2e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PLA2G12 PF06951.11 CBY34966.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Myb_DNA-bind_6 PF13921.6 CBY34966.1 - 0.2 11.9 0.0 1.4 9.2 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Nmad3 PF18754.1 CBY34967.1 - 0.11 12.1 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 FeoB_associated PF12669.7 CBY34969.1 - 0.085 13.3 1.1 0.55 10.7 0.1 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Rap_GAP PF02145.15 CBY34970.1 - 5.7e-18 65.1 0.0 1.4e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 Rap/ran-GAP ABC_tran PF00005.27 CBY34971.1 - 4.3e-48 163.3 0.0 1.1e-22 81.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CBY34971.1 - 4.8e-23 81.0 0.2 4.8e-23 81.0 0.2 2.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 CBY34971.1 - 4.5e-15 56.2 7.9 0.00069 19.5 0.0 4.8 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY34971.1 - 8e-11 41.8 0.1 0.00096 18.7 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBY34971.1 - 3.8e-08 32.9 0.1 0.002 17.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY34971.1 - 8.8e-08 32.2 0.0 0.012 15.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY34971.1 - 3.9e-07 30.4 0.2 0.0041 17.4 0.0 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CBY34971.1 - 1.4e-06 28.4 0.2 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CBY34971.1 - 2.6e-06 28.1 11.7 0.01 16.3 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CBY34971.1 - 1.8e-05 25.2 2.0 0.01 16.3 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 CBY34971.1 - 3.6e-05 23.6 0.3 0.14 11.9 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CBY34971.1 - 0.00012 22.4 1.9 0.22 11.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CBY34971.1 - 0.00028 21.4 1.2 0.72 10.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain MeaB PF03308.16 CBY34971.1 - 0.0003 19.9 0.0 0.75 8.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CBY34971.1 - 0.00031 20.5 0.6 0.4 10.4 0.1 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CBY34971.1 - 0.00063 19.7 0.2 0.29 11.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 CBY34971.1 - 0.00065 19.9 2.4 0.038 14.1 0.0 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CBY34971.1 - 0.001 18.4 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 CBY34971.1 - 0.0018 18.0 7.7 0.11 12.2 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 CBY34971.1 - 0.0023 18.0 4.1 0.063 13.3 0.0 3.2 4 0 0 4 4 3 1 Dynamin family AAA_7 PF12775.7 CBY34971.1 - 0.0028 17.2 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBY34971.1 - 0.0032 17.6 1.4 2.8 8.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 CBY34971.1 - 0.012 15.2 4.8 0.7 9.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CBY34971.1 - 0.015 15.7 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 CBY34971.1 - 0.016 14.8 0.5 6 6.4 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 CBY34971.1 - 0.016 14.0 0.4 13 4.4 0.1 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CBY34971.1 - 0.017 15.4 0.4 2.5 8.4 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 CBY34971.1 - 0.024 14.9 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CBY34971.1 - 0.024 14.6 0.1 1.3 9.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Arf PF00025.21 CBY34971.1 - 0.046 13.2 0.3 1.7 8.0 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 CBY34971.1 - 0.054 12.8 0.4 4.9 6.4 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 CBY34971.1 - 0.061 13.2 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MobB PF03205.14 CBY34971.1 - 0.076 12.9 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CBY34971.1 - 0.11 12.9 0.0 28 5.1 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CBY34971.1 - 0.12 11.7 0.0 7.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Septin NB-ARC PF00931.22 CBY34971.1 - 0.13 11.4 0.1 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CBY34971.1 - 0.15 12.0 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 CBY34971.1 - 0.17 11.9 0.2 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 CBY34971.1 - 0.19 11.6 0.8 3.1 7.6 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase AAA_13 PF13166.6 CBY34971.1 - 0.24 10.0 6.5 6.6 5.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain DUF2813 PF11398.8 CBY34971.1 - 1.9 7.7 0.0 1.9 7.7 0.0 2.7 4 0 0 4 4 2 0 Protein of unknown function (DUF2813) Alg6_Alg8 PF03155.15 CBY34972.1 - 8.2e-127 424.1 33.7 1.3e-126 423.4 33.7 1.3 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ig_mannosidase PF17753.1 CBY34972.1 - 5.4e-08 32.5 0.0 1.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 CBY34972.1 - 1.3e-05 25.9 0.0 2.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Gla PF00594.20 CBY34974.1 - 7.9e-12 45.2 1.2 1.7e-11 44.2 1.2 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain ANAPC4_WD40 PF12894.7 CBY34975.1 - 6.9e-06 26.3 0.3 0.14 12.5 0.1 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY34975.1 - 0.001 19.8 13.3 0.67 10.9 1.4 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ETF_QO PF05187.13 CBY34975.1 - 0.068 13.3 0.1 0.78 9.9 0.0 2.7 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S wnt PF00110.19 CBY34976.1 - 2.7e-51 175.0 25.9 3.4e-51 174.7 25.9 1.1 1 0 0 1 1 1 1 wnt family SSF PF00474.17 CBY34977.1 - 9.5e-36 123.5 29.0 1.2e-35 123.2 29.0 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family TCL1_MTCP1 PF01840.17 CBY34977.1 - 0.16 11.7 0.0 0.92 9.2 0.0 2.0 2 0 0 2 2 2 0 TCL1/MTCP1 family ZYG-11_interact PF05884.12 CBY34978.1 - 0.19 11.1 2.1 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Interactor of ZYG-11 Scramblase PF03803.15 CBY34979.1 - 1.6e-67 227.1 0.0 1.9e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase P22_Cro PF14549.6 CBY34979.1 - 0.026 14.4 0.4 0.049 13.5 0.4 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Ig_3 PF13927.6 CBY34980.1 - 1.6e-29 102.3 4.1 8.6e-10 39.1 0.1 5.7 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 CBY34980.1 - 2.5e-29 101.2 3.5 7.6e-12 45.1 0.1 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY34980.1 - 8.3e-22 77.3 2.5 4.5e-12 46.1 0.1 4.9 5 0 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 CBY34980.1 - 6.2e-21 74.4 3.3 1.2e-07 31.8 0.1 3.9 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY34980.1 - 3.9e-13 49.5 1.7 6.7e-07 29.5 0.1 4.9 4 1 1 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY34980.1 - 2.3e-10 40.4 0.9 1.6e-05 24.9 0.0 4.5 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_4 PF16680.5 CBY34980.1 - 2e-07 31.2 0.1 0.019 15.2 0.0 3.7 3 0 0 3 3 3 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CBY34980.1 - 1e-06 29.1 1.0 0.0014 19.0 0.0 3.8 3 1 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain C1-set PF07654.15 CBY34980.1 - 8.5e-05 22.9 0.8 5.3 7.5 0.0 4.9 6 0 0 6 6 6 2 Immunoglobulin C1-set domain Ig_6 PF18452.1 CBY34980.1 - 0.0012 18.4 0.0 0.0084 15.7 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain Izumo-Ig PF16706.5 CBY34980.1 - 0.0055 16.7 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain C2-set PF05790.15 CBY34980.1 - 0.015 15.5 0.1 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Immunoglobulin C2-set domain RRM_1 PF00076.22 CBY34981.1 - 3.7e-34 116.4 0.0 2e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY34981.1 - 3.5e-08 33.1 0.0 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 CBY34982.1 - 1.9e-102 343.5 18.7 2.3e-102 343.2 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY34982.1 - 3.2e-19 69.1 26.9 4e-18 65.5 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin PF00089.26 CBY34983.1 - 7.3e-49 166.5 0.6 7.3e-49 166.5 0.6 1.6 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY34983.1 - 0.0001 23.2 0.0 0.00019 22.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY34983.1 - 0.023 15.1 0.1 0.064 13.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Hormone_1 PF00103.20 CBY34983.1 - 0.15 11.8 3.1 0.25 11.0 3.1 1.3 1 0 0 1 1 1 0 Somatotropin hormone family Sec63 PF02889.16 CBY34984.1 - 0.11 11.6 0.2 0.14 11.3 0.2 1.3 1 1 0 1 1 1 0 Sec63 Brl domain DUF5595 PF18077.1 CBY34986.1 - 0.0012 18.9 3.4 0.028 14.5 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5595) ATG16 PF08614.11 CBY34986.1 - 0.0066 16.7 3.2 0.0066 16.7 3.2 2.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Miff PF05644.11 CBY34986.1 - 0.011 15.4 0.6 0.011 15.4 0.6 1.8 2 1 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Cnn_1N PF07989.11 CBY34986.1 - 0.015 15.4 5.4 0.015 15.4 5.4 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF4763 PF15960.5 CBY34986.1 - 0.024 13.9 8.7 0.69 9.2 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Fez1 PF06818.15 CBY34986.1 - 0.11 12.9 4.7 0.18 12.2 4.7 1.3 1 0 0 1 1 1 0 Fez1 KLRAQ PF10205.9 CBY34986.1 - 0.14 12.4 9.0 0.062 13.5 2.9 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 CBY34986.1 - 0.15 10.6 3.5 0.28 9.7 3.5 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 CBY34986.1 - 0.17 11.8 6.7 0.063 13.1 2.1 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CBY34986.1 - 0.67 9.2 5.7 1 8.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CBY34986.1 - 1.3 9.1 11.4 0.051 13.7 2.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lipoprotein_20 PF13942.6 CBY34986.1 - 1.6 8.6 10.0 3.6 7.5 5.3 2.4 1 1 1 2 2 2 0 YfhG lipoprotein FAM76 PF16046.5 CBY34986.1 - 2.9 7.2 11.4 0.14 11.5 5.4 1.9 2 0 0 2 2 2 0 FAM76 protein SlyX PF04102.12 CBY34986.1 - 5.7 7.6 7.1 5.6 7.6 2.4 2.6 1 1 1 2 2 2 0 SlyX Arf PF00025.21 CBY34987.1 - 1.6e-77 258.9 0.1 1.9e-77 258.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY34987.1 - 3.5e-15 56.3 0.1 4.8e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY34987.1 - 5.8e-15 55.2 0.0 6.9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CBY34987.1 - 2.8e-11 43.2 0.0 3.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY34987.1 - 1.5e-10 40.8 1.0 7.8e-07 28.6 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY34987.1 - 1.3e-09 37.7 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY34987.1 - 4.8e-06 26.6 0.0 8.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY34987.1 - 0.00021 20.9 0.2 0.0016 18.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBY34987.1 - 0.0046 16.0 0.4 0.11 11.5 0.1 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CBY34987.1 - 0.0096 16.5 0.0 0.015 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CBY34987.1 - 0.015 15.0 0.3 5.3 6.8 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CBY34987.1 - 0.026 15.1 0.6 0.15 12.6 0.5 2.0 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CBY34987.1 - 0.026 14.4 0.2 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 CBY34987.1 - 0.081 12.5 0.3 8.9 5.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBY34987.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain PA PF02225.22 CBY34988.1 - 7.6e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 PA domain EMP70 PF02990.16 CBY34989.1 - 4e-204 679.1 9.4 5.2e-204 678.7 9.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 AAL_decarboxy PF03306.13 CBY34989.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Got1 PF04178.12 CBY34990.1 - 1.3e-34 119.1 13.8 1.8e-34 118.5 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 CBY34990.1 - 1.4 7.1 9.5 1.7 6.8 9.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-RING_5 PF14634.6 CBY34992.1 - 2.4e-05 24.2 13.4 2.4e-05 24.2 13.4 3.2 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY34992.1 - 8e-05 22.4 9.7 8e-05 22.4 9.7 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY34992.1 - 0.0016 18.4 11.5 0.002 18.1 4.2 3.6 2 2 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY34992.1 - 0.0022 18.3 12.0 0.0022 18.3 12.0 3.1 2 1 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY34992.1 - 0.012 15.5 10.5 0.012 15.5 10.5 3.3 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY34992.1 - 0.027 14.3 16.0 0.03 14.2 12.7 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3410 PF11890.8 CBY34992.1 - 0.18 11.6 0.5 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) DUF4761 PF15958.5 CBY34993.1 - 0.0062 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4761) DASH_Ask1 PF08655.10 CBY34993.1 - 0.076 12.9 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 Ammonium_transp PF00909.21 CBY34995.1 - 1.4e-88 297.3 17.8 1.7e-88 297.0 17.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Sulfate_transp PF00916.20 CBY34996.1 - 1.2e-30 106.5 2.7 1.5e-30 106.2 2.7 1.0 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 CBY34996.1 - 0.00035 21.0 3.3 0.00061 20.2 3.3 1.4 1 1 0 1 1 1 1 Molybdate transporter of MFS superfamily DUF898 PF05987.13 CBY34996.1 - 0.077 12.0 8.0 0.2 10.6 0.3 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) UCR_Fe-S_N PF10399.9 CBY34996.1 - 0.47 9.8 0.1 0.47 9.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SLT PF01464.20 CBY34997.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain SAS4 PF15460.6 CBY34997.1 - 0.19 11.9 0.0 4.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Ion_trans_2 PF07885.16 CBY34999.1 - 1.4e-11 44.2 4.2 1.4e-11 44.2 4.2 1.6 1 1 1 2 2 2 2 Ion channel Kelch_1 PF01344.25 CBY35000.1 - 1.1e-05 24.8 5.9 0.00034 20.1 0.7 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY35000.1 - 0.00024 21.3 0.7 0.0082 16.4 0.1 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY35000.1 - 0.0084 16.1 1.8 3.8 7.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY35000.1 - 0.083 12.9 8.3 4.2 7.5 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Sulfotransfer_2 PF03567.14 CBY35001.1 - 0.006 16.5 0.4 0.006 16.5 0.4 2.0 2 1 0 2 2 2 1 Sulfotransferase family X8 PF07983.13 CBY35001.1 - 0.13 13.0 2.0 0.14 12.9 0.1 1.9 2 0 0 2 2 2 0 X8 domain La PF05383.17 CBY35003.1 - 6.7e-09 35.7 0.0 9.5e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 La domain PDZ PF00595.24 CBY35004.1 - 2.5e-10 40.6 0.2 2.3e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY35004.1 - 1e-09 38.6 0.0 2.1e-06 28.0 0.0 3.3 3 0 0 3 3 3 1 PDZ domain PDZ_6 PF17820.1 CBY35004.1 - 1.1e-08 34.8 0.1 0.00038 20.2 0.0 3.6 4 0 0 4 4 4 2 PDZ domain Trypan_PARP PF05887.11 CBY35004.1 - 0.12 12.4 7.7 0.22 11.5 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) O-FucT PF10250.9 CBY35006.1 - 0.00012 21.9 0.0 0.00065 19.5 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TetR_C_8 PF14278.6 CBY35006.1 - 0.011 15.8 0.2 0.046 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region RIB43A PF05914.12 CBY35008.1 - 5.2e-31 107.7 16.9 5.7e-31 107.6 16.9 1.0 1 0 0 1 1 1 1 RIB43A DUF2252 PF10009.9 CBY35008.1 - 0.44 9.5 5.6 0.49 9.4 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) CDRT4 PF15213.6 CBY35008.1 - 0.63 10.6 6.0 0.14 12.8 2.5 1.6 1 1 1 2 2 2 0 CMT1A duplicated region transcript 4 protein zf-C2H2 PF00096.26 CBY35009.1 - 9.9e-16 57.2 56.0 1.1e-05 25.6 0.7 8.0 9 0 0 9 9 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35009.1 - 2.9e-15 55.6 55.8 0.00051 20.7 0.3 8.6 8 1 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY35009.1 - 5e-14 52.2 45.1 0.00016 21.8 0.5 8.0 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY35009.1 - 1e-08 35.2 49.5 0.0017 18.7 1.0 8.3 9 0 0 9 9 8 5 Zinc-finger double domain zf-met PF12874.7 CBY35009.1 - 6.2e-08 32.8 37.1 0.044 14.2 2.8 6.8 7 0 0 7 7 7 5 Zinc-finger of C2H2 type Tup_N PF08581.10 CBY35009.1 - 0.28 11.5 6.5 0.67 10.3 6.5 1.6 1 0 0 1 1 1 0 Tup N-terminal zinc_ribbon_15 PF17032.5 CBY35009.1 - 0.29 11.9 28.6 0.15 12.9 2.1 4.9 4 1 1 5 5 5 0 zinc-ribbon family zf-C2H2_6 PF13912.6 CBY35009.1 - 0.3 11.1 31.2 1.2 9.3 0.2 6.2 6 0 0 6 6 5 0 C2H2-type zinc finger PyrI_C PF02748.15 CBY35009.1 - 1.3 9.0 20.7 1.3 9.0 0.3 5.6 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CHCC PF10276.9 CBY35009.1 - 1.4 9.1 8.7 8.4 6.5 0.2 3.9 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 CBY35009.1 - 3.2 7.8 24.2 6 7.0 1.3 4.9 4 2 0 4 4 4 0 Double zinc ribbon zf-C2H2_8 PF15909.5 CBY35009.1 - 3.8 7.9 17.0 14 6.0 5.1 3.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 CBY35009.1 - 4.3 7.6 27.2 0.11 12.6 0.8 5.6 3 1 4 7 7 7 0 Zinc ribbon domain MTA_R1 PF17226.2 CBY35010.1 - 0.0046 17.1 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 MTA R1 domain Amidohydro_1 PF01979.20 CBY35011.1 - 3.9e-64 217.1 0.0 6.8e-60 203.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CBY35011.1 - 8.5e-10 38.7 0.1 5.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Asp2 PF16929.5 CBY35011.1 - 0.0038 16.3 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 2 Accessory Sec system GspB-transporter DUF739 PF05339.11 CBY35011.1 - 0.051 13.7 0.3 32 4.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF739) EamA PF00892.20 CBY35013.1 - 7.6e-14 52.0 19.4 8.2e-12 45.5 6.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family GCK PF07802.11 CBY35014.1 - 0.013 15.9 1.0 0.024 15.0 0.3 1.7 2 0 0 2 2 2 0 GCK domain CHCH PF06747.13 CBY35014.1 - 0.04 14.1 2.1 3.8 7.8 0.3 2.2 2 0 0 2 2 2 0 CHCH domain NDUF_B7 PF05676.13 CBY35014.1 - 0.056 13.2 0.5 0.13 12.0 0.3 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Plus-3 PF03126.18 CBY35015.1 - 2.5e-26 92.3 0.0 7.6e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain CASP_C PF08172.12 CBY35016.1 - 0.0083 15.5 0.2 0.0083 15.5 0.2 1.1 1 0 0 1 1 1 1 CASP C terminal DUF2353 PF09789.9 CBY35016.1 - 0.03 13.7 0.8 0.03 13.7 0.8 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) BACK PF07707.15 CBY35016.1 - 0.051 13.7 0.1 0.056 13.5 0.1 1.1 1 0 0 1 1 1 0 BTB And C-terminal Kelch UPRTase PF14681.6 CBY35017.1 - 2.3e-51 174.2 0.1 3.2e-51 173.7 0.1 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBY35017.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Carb_kinase PF01256.17 CBY35017.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase Complex1_LYR PF05347.15 CBY35018.1 - 0.0044 17.0 0.2 0.0079 16.2 0.2 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) JAB PF01398.21 CBY35019.1 - 1.4e-32 112.2 0.0 2.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBY35019.1 - 2.6e-12 47.1 0.6 4.9e-12 46.3 0.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CBY35019.1 - 9.4e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF89 PF01937.19 CBY35019.1 - 0.05 12.5 0.1 0.066 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF5624 PF18538.1 CBY35019.1 - 0.095 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) LSM PF01423.22 CBY35020.1 - 8.6e-17 60.6 0.2 1.1e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY35020.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TRAPP PF04051.16 CBY35021.1 - 1.9e-35 121.7 0.0 2.2e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4499 PF14934.6 CBY35022.1 - 4.8e-28 97.3 0.7 6.2e-28 97.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) PXB PF12828.7 CBY35023.1 - 0.091 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 PX-associated DUF2362 PF10154.9 CBY35024.1 - 8.3e-32 110.8 0.7 9.7e-32 110.6 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF2362 PF10154.9 CBY35025.1 - 5.7e-28 98.1 7.8 1.7e-24 86.7 1.3 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2362) CTP_transf_like PF01467.26 CBY35026.1 - 5.2e-27 94.8 0.0 9.1e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF4706 PF15797.5 CBY35028.1 - 7.2e-26 90.8 2.1 7.2e-26 90.8 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4706) Methyltransf_16 PF10294.9 CBY35029.1 - 1.5e-17 63.9 0.2 1.9e-17 63.5 0.2 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CBY35029.1 - 6.5e-05 23.6 0.0 0.00025 21.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBY35029.1 - 6.8e-05 22.5 0.1 9.1e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBY35029.1 - 0.00011 22.9 0.0 0.0002 22.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBY35029.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CBY35029.1 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CBY35029.1 - 0.0033 17.2 0.1 0.0054 16.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY35029.1 - 0.01 16.5 0.0 0.017 15.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CBY35029.1 - 0.03 13.2 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GidB PF02527.15 CBY35029.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DOT1 PF08123.13 CBY35029.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 CBY35029.1 - 0.17 11.7 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain KH_1 PF00013.29 CBY35030.1 - 1.9e-60 200.5 8.1 7.4e-17 60.9 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 CBY35030.1 - 2.1e-19 69.1 6.2 4.6e-05 23.1 2.8 4.7 3 1 1 4 4 4 4 KH domain DUF1897 PF09005.10 CBY35030.1 - 6.1e-19 67.2 29.0 4.7e-07 29.2 6.2 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF1897) KH_4 PF13083.6 CBY35030.1 - 2.8e-12 46.3 5.2 0.0073 16.2 0.2 4.3 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 CBY35030.1 - 0.24 11.5 8.7 12 6.1 0.1 4.0 4 0 0 4 4 4 0 NusA-like KH domain LRR_8 PF13855.6 CBY35031.1 - 2.3e-13 49.7 14.9 6.5e-08 32.2 2.2 4.3 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 CBY35031.1 - 0.00051 20.4 17.0 0.012 16.0 1.6 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY35031.1 - 0.0017 17.8 6.8 0.019 14.5 4.5 2.6 1 1 1 2 2 2 2 Leucine-rich repeat YlbE PF14003.6 CBY35031.1 - 0.17 12.4 2.2 0.65 10.5 2.2 2.0 1 0 0 1 1 1 0 YlbE-like protein Erf4 PF10256.9 CBY35031.1 - 1.5 8.9 9.0 0.69 10.0 1.3 2.9 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Pkinase PF00069.25 CBY35032.1 - 1.8e-11 43.9 0.0 1.8e-11 43.9 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35032.1 - 1.2e-08 34.6 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Porphyrn_cat_1 PF18206.1 CBY35032.1 - 0.026 15.1 0.4 0.063 13.9 0.4 1.6 1 0 0 1 1 1 0 Porphyranase catalytic subdomain 1 YbbR PF07949.12 CBY35034.1 - 0.045 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 YbbR-like protein ANAPC10 PF03256.16 CBY35035.1 - 0.066 12.9 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CBY35035.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain VWA_3 PF13768.6 CBY35036.1 - 3.7e-12 46.5 0.1 6.5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY35036.1 - 3.4e-08 34.0 0.1 7.3e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY35036.1 - 0.00055 20.6 0.2 0.003 18.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain TED PF08341.11 CBY35036.1 - 0.047 14.1 0.1 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Thioester domain DUF3685 PF12452.8 CBY35037.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) p450 PF00067.22 CBY35038.1 - 2.4e-57 194.7 0.3 3.2e-57 194.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 CBY35040.1 - 5.2e-19 68.4 0.4 8.2e-09 35.8 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35040.1 - 5.9e-15 55.6 0.2 2e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY35040.1 - 6.4e-12 45.3 3.0 6.3e-06 26.4 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CBY35040.1 - 9.1e-11 41.8 0.1 2.2e-09 37.4 0.0 2.8 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY35040.1 - 3.7e-10 39.2 2.6 0.00018 21.7 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat SAM_1 PF00536.30 CBY35041.1 - 2.7e-13 50.1 0.0 8e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY35041.1 - 5.1e-11 42.5 0.1 1.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Sushi PF00084.20 CBY35042.1 - 9.5e-25 87.0 43.6 1.2e-06 29.0 1.2 6.0 6 0 0 6 6 6 5 Sushi repeat (SCR repeat) Sushi PF00084.20 CBY35043.1 - 9.5e-27 93.4 50.9 1.9e-08 34.8 3.9 6.4 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) zf-RING_2 PF13639.6 CBY35044.1 - 3.9e-09 36.7 6.1 3.9e-09 36.7 6.1 2.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY35044.1 - 2.4e-07 30.5 5.5 2.4e-07 30.5 5.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY35044.1 - 5.2e-06 26.4 0.4 5.2e-06 26.4 0.4 3.1 3 1 1 4 4 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY35044.1 - 6.9e-06 25.8 7.4 6.9e-06 25.8 7.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY35044.1 - 4e-05 23.5 8.1 4e-05 23.5 8.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY35044.1 - 0.00024 20.9 4.3 0.00024 20.9 4.3 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY35044.1 - 0.00049 20.3 5.3 0.00049 20.3 5.3 3.0 3 1 0 3 3 3 1 RING-H2 zinc finger domain SHE3 PF17078.5 CBY35044.1 - 0.0033 17.2 11.5 0.0052 16.5 11.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 MATH PF00917.26 CBY35044.1 - 0.0042 17.2 0.8 0.0042 17.2 0.8 2.1 2 0 0 2 2 2 1 MATH domain Rgp1 PF08737.10 CBY35044.1 - 0.022 13.9 5.2 0.027 13.6 5.2 1.1 1 0 0 1 1 1 0 Rgp1 zf-Nse PF11789.8 CBY35044.1 - 0.025 14.4 2.8 0.089 12.6 2.8 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GrpE PF01025.19 CBY35044.1 - 0.073 12.7 6.1 0.11 12.1 6.1 1.3 1 0 0 1 1 1 0 GrpE CDC37_N PF03234.14 CBY35044.1 - 0.082 13.8 8.1 0.13 13.1 8.1 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Csm1_N PF18504.1 CBY35044.1 - 0.13 12.7 9.2 0.056 13.8 3.0 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain CorA PF01544.18 CBY35044.1 - 0.21 10.8 4.6 0.32 10.3 4.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2968 PF11180.8 CBY35044.1 - 0.27 10.8 5.8 0.44 10.1 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4200 PF13863.6 CBY35044.1 - 0.47 10.9 14.4 0.8 10.1 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nup54 PF13874.6 CBY35044.1 - 1.6 8.8 7.3 2.5 8.2 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Mto2_bdg PF12808.7 CBY35044.1 - 1.9 8.8 6.8 10 6.5 0.3 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-RING_11 PF17123.5 CBY35044.1 - 4.4 7.2 9.2 0.22 11.3 3.0 2.2 2 0 0 2 2 2 0 RING-like zinc finger Baculo_IE-1 PF05290.11 CBY35044.1 - 9.9 6.1 15.3 0.025 14.5 3.6 2.3 2 1 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) CBM_14 PF01607.24 CBY35045.1 - 1.3e-26 92.5 27.0 6.1e-09 35.9 3.9 3.9 3 1 0 3 3 3 3 Chitin binding Peritrophin-A domain Sushi PF00084.20 CBY35047.1 - 0.76 10.4 7.0 1.4 9.6 7.0 1.5 1 1 0 1 1 1 0 Sushi repeat (SCR repeat) OLF PF02191.16 CBY35048.1 - 1e-56 192.2 2.2 1.4e-56 191.8 2.2 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Cadherin_3 PF16184.5 CBY35049.1 - 3.5e-198 645.2 38.1 1.2e-25 89.7 0.4 15.1 15 0 0 15 15 15 12 Cadherin-like Calx-beta PF03160.14 CBY35049.1 - 9.6e-67 221.4 19.0 4.8e-14 52.3 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain Big_9 PF17963.1 CBY35049.1 - 2.4e-10 41.0 14.9 0.00042 21.0 0.1 9.9 10 0 0 10 10 10 2 Bacterial Ig domain Cadherin_4 PF17803.1 CBY35049.1 - 7.4e-09 36.1 2.3 1.4 9.6 0.0 8.3 8 0 0 8 8 8 2 Bacterial cadherin-like domain Filamin PF00630.19 CBY35049.1 - 0.17 12.7 1.9 62 4.5 0.1 5.0 4 1 0 4 4 4 0 Filamin/ABP280 repeat DUF2228 PF10228.9 CBY35051.1 - 3.6e-65 220.2 0.0 4.2e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Aida_N PF08910.10 CBY35052.1 - 4.8e-08 33.3 1.9 0.099 13.0 0.0 4.7 4 1 1 5 5 5 2 Aida N-terminus Cas_Cas6 PF01881.16 CBY35052.1 - 0.036 14.6 0.7 6.3 7.3 0.0 3.1 3 0 0 3 3 3 0 CRISPR associated protein Cas6 HTH_AsnC-type PF13404.6 CBY35052.1 - 0.092 12.6 1.3 15 5.5 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Drf_DAD PF06345.11 CBY35052.1 - 0.14 12.2 1.2 27 5.1 0.1 2.8 2 0 0 2 2 2 0 DRF Autoregulatory Domain Csm1 PF12539.8 CBY35052.1 - 0.2 12.3 1.3 44 4.8 0.0 3.3 3 0 0 3 3 3 0 Chromosome segregation protein Csm1/Pcs1 DUF3939 PF13075.6 CBY35054.1 - 0.028 14.4 0.3 0.068 13.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3939) UQ_con PF00179.26 CBY35055.1 - 9.6e-54 180.8 0.0 1.1e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY35055.1 - 5.2e-05 23.5 0.0 8.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBY35055.1 - 0.0074 16.0 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY35055.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Lyase_1 PF00206.20 CBY35056.1 - 7.5e-109 363.9 0.0 1.2e-108 363.3 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CBY35056.1 - 1.1e-20 73.7 0.1 7.3e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus HTH_Tnp_1 PF01527.20 CBY35056.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase TPR_12 PF13424.6 CBY35057.1 - 2e-05 24.8 15.2 0.007 16.6 0.2 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY35057.1 - 0.0059 16.6 7.7 0.72 10.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat FANCI_S2 PF14676.6 CBY35057.1 - 0.11 12.8 2.1 0.29 11.4 2.0 1.7 1 1 0 1 1 1 0 FANCI solenoid 2 TPR_1 PF00515.28 CBY35057.1 - 1.7 8.6 11.7 4.2 7.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY35057.1 - 2.9 8.3 0.0 2.9 8.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 CBY35058.1 - 9.1e-30 103.9 1.2 1.5e-29 103.1 1.2 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Thymidylate_kin PF02223.17 CBY35059.1 - 7.7e-44 149.6 0.0 9.8e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase PPR_2 PF13041.6 CBY35059.1 - 0.014 15.5 0.0 6.1 7.1 0.0 2.7 2 1 0 2 2 2 0 PPR repeat family AAA_14 PF13173.6 CBY35059.1 - 0.023 14.7 0.1 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPK2 PF03976.14 CBY35059.1 - 0.069 12.6 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) CPT PF07931.12 CBY35059.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PqqD PF05402.12 CBY35059.1 - 0.68 10.3 2.2 2.8 8.3 0.0 2.8 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) DHHC PF01529.20 CBY35060.1 - 0.062 13.4 0.6 0.077 13.1 0.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Cgr1 PF03879.14 CBY35061.1 - 0.00042 20.7 33.2 0.00072 19.9 33.3 1.4 1 1 0 1 1 1 1 Cgr1 family Thiolase_N PF00108.23 CBY35062.1 - 4.2e-80 268.8 0.6 5.5e-80 268.5 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY35062.1 - 2.3e-47 159.7 4.8 5.6e-47 158.4 1.2 2.8 3 0 0 3 3 3 1 Thiolase, C-terminal domain Peptidase_M78 PF06114.13 CBY35062.1 - 0.031 14.2 0.2 0.74 9.7 0.3 2.5 2 1 1 3 3 3 0 IrrE N-terminal-like domain ketoacyl-synt PF00109.26 CBY35062.1 - 1.8 8.1 10.6 7.1 6.1 1.3 3.6 4 1 0 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain Apc13p PF05839.11 CBY35063.1 - 0.047 13.9 0.6 0.069 13.4 0.6 1.4 1 1 0 1 1 1 0 Apc13p protein Carboxyl_trans PF01039.22 CBY35064.1 - 1.6e-136 455.9 0.0 2.5e-136 455.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 CBY35064.1 - 1.4e-87 294.7 3.4 1.4e-87 294.7 3.4 1.5 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region TRADD_N PF09034.10 CBY35064.1 - 0.11 12.5 1.9 0.28 11.2 0.1 2.5 1 1 1 2 2 2 0 TRADD, N-terminal domain Aldedh PF00171.22 CBY35065.1 - 2.4e-52 178.0 0.2 2.7e-52 177.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CBY35066.1 - 1.3e-35 122.8 0.0 1.5e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VWA_N PF08399.11 CBY35067.1 - 1.4e-21 77.2 3.1 2.5e-21 76.4 1.2 2.4 2 0 0 2 2 2 1 VWA N-terminal VGCC_alpha2 PF08473.11 CBY35067.1 - 2.6e-13 49.6 4.4 2.7e-11 42.9 0.3 2.8 3 0 0 3 3 3 2 Neuronal voltage-dependent calcium channel alpha 2acd VWA_3 PF13768.6 CBY35067.1 - 6.7e-12 45.6 0.0 8.2e-10 38.8 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain dCache_1 PF02743.18 CBY35067.1 - 8.3e-10 38.9 2.7 5.5e-09 36.2 0.1 2.9 3 0 0 3 3 3 1 Cache domain VWA PF00092.28 CBY35067.1 - 1.2e-07 32.1 0.7 3.4e-07 30.7 0.3 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY35067.1 - 1.2e-05 25.9 0.1 4.2e-05 24.1 0.1 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY35067.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF4315 PF14193.6 CBY35067.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) AFG1_ATPase PF03969.16 CBY35068.1 - 1e-61 208.9 1.6 4.6e-37 127.8 0.4 3.0 2 1 1 3 3 3 3 AFG1-like ATPase SPRY PF00622.28 CBY35069.1 - 2.2e-25 89.1 0.1 6.4e-25 87.6 0.1 1.9 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CBY35069.1 - 1.9e-22 79.8 0.6 3.1e-22 79.1 0.2 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CBY35069.1 - 0.047 13.7 5.5 0.08 12.9 0.3 3.0 3 0 0 3 3 3 0 LisH PALP PF00291.25 CBY35070.1 - 4.9e-29 101.7 0.0 6.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF5546 PF17700.1 CBY35071.1 - 0.072 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5546) HLH PF00010.26 CBY35072.1 - 0.00015 21.7 3.5 0.00035 20.5 3.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ACP_PD PF04336.12 CBY35072.1 - 0.2 12.1 0.8 0.29 11.6 0.6 1.4 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase Guanylate_cyc PF00211.20 CBY35074.1 - 4.7e-49 166.5 0.3 6.3e-49 166.1 0.3 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CBY35074.1 - 3.2e-19 69.4 0.1 4.8e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 Adenylyl cyclase N-terminal extracellular and transmembrane region Calx-beta PF03160.14 CBY35075.1 - 1.5e-57 191.9 4.8 5.1e-29 100.4 0.2 2.5 2 0 0 2 2 2 2 Calx-beta domain Na_Ca_ex PF01699.24 CBY35075.1 - 2.3e-24 86.0 12.7 3.3e-24 85.6 12.7 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_Ca_ex_C PF16494.5 CBY35075.1 - 6.3e-11 42.8 0.0 1.5e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal extension of sodium/calcium exchanger domain COesterase PF00135.28 CBY35076.1 - 0.0027 16.6 0.2 0.0027 16.6 0.2 1.2 1 1 0 1 1 1 1 Carboxylesterase family DUF2653 PF10850.8 CBY35076.1 - 0.012 15.7 0.0 2.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) COesterase PF00135.28 CBY35077.1 - 1.5e-58 199.0 0.0 1.9e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY35077.1 - 9.1e-11 42.0 0.2 9.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY35077.1 - 0.005 16.3 0.2 0.0088 15.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CBY35077.1 - 0.012 14.8 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 CBY35077.1 - 0.018 13.9 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Esterase PF00756.20 CBY35077.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Lectin_C PF00059.21 CBY35078.1 - 7.7e-15 55.6 16.5 2.1e-07 31.6 0.4 3.9 4 0 0 4 4 4 3 Lectin C-type domain Mucin PF01456.17 CBY35078.1 - 0.003 17.5 17.9 0.0056 16.7 17.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF2704 PF10866.8 CBY35078.1 - 0.034 14.0 0.2 0.073 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) DUF5609 PF18429.1 CBY35078.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) DUF3439 PF11921.8 CBY35078.1 - 0.59 10.1 12.3 1.5 8.8 12.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cys_Knot_tox PF17486.2 CBY35078.1 - 1.9 8.7 7.6 7.6 6.8 0.4 3.2 2 1 1 3 3 3 0 Cystine knot toxins Homeobox_KN PF05920.11 CBY35079.1 - 1.1e-19 70.1 1.4 2.2e-19 69.0 1.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY35079.1 - 5.2e-09 35.8 0.8 9.2e-09 35.0 0.8 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CBY35079.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez 4PPT_N PF17837.1 CBY35079.1 - 0.24 11.5 0.7 0.9 9.7 0.7 2.0 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Hydrolase_4 PF12146.8 CBY35082.1 - 1e-06 28.2 0.0 1.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY35082.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Bestrophin PF01062.21 CBY35085.1 - 3.1e-98 328.8 5.8 3.7e-98 328.6 5.8 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel WD40 PF00400.32 CBY35086.1 - 8e-25 86.6 10.8 0.00016 22.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.12 CBY35086.1 - 2.4e-08 34.4 0.1 4.3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 CBY35086.1 - 5.4e-07 29.8 0.7 0.12 12.7 0.0 4.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY35086.1 - 0.02 14.2 0.0 1.1 8.5 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Ank_2 PF12796.7 CBY35088.1 - 4.6e-15 56.0 0.4 2e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY35088.1 - 3.4e-07 30.4 0.2 1.4e-05 25.3 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY35088.1 - 1e-06 29.2 0.0 0.0014 19.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY35088.1 - 0.00023 21.4 0.0 0.11 13.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CBY35088.1 - 0.00026 21.3 0.3 0.27 11.8 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat DUF5358 PF17311.2 CBY35088.1 - 0.023 14.7 1.8 0.05 13.6 1.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5358) DUF755 PF05501.11 CBY35088.1 - 0.09 13.1 7.5 0.16 12.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) E1_DerP2_DerF2 PF02221.15 CBY35089.1 - 0.00064 20.2 1.8 0.0022 18.4 1.8 1.9 1 1 0 1 1 1 1 ML domain CUB PF00431.20 CBY35090.1 - 1.2e-05 25.6 0.0 0.00013 22.2 0.0 2.3 1 1 0 1 1 1 1 CUB domain Homeodomain PF00046.29 CBY35091.1 - 6.7e-20 70.7 6.2 1e-19 70.1 6.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY35091.1 - 0.0093 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain EFG_C PF00679.24 CBY35092.1 - 3.9e-18 65.3 0.1 4.5e-17 61.9 0.0 2.7 4 0 0 4 4 4 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBY35092.1 - 0.00056 19.7 0.0 0.0027 17.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G, domain IV Tantalus PF15386.6 CBY35092.1 - 0.024 14.7 0.1 0.074 13.2 0.1 1.9 1 0 0 1 1 1 0 Drosophila Tantalus-like Kinetochor_Ybp2 PF08568.10 CBY35094.1 - 0.00096 17.8 0.0 0.001 17.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin TetR_C_34 PF17929.1 CBY35094.1 - 0.0099 16.0 0.0 0.57 10.3 0.0 2.0 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 CBY35095.1 - 1.5e-19 70.1 14.9 2.8e-19 69.3 14.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY35095.1 - 1.5e-06 27.1 19.9 1.6e-06 27.0 10.6 2.5 1 1 1 3 3 3 2 MFS/sugar transport protein DHHC PF01529.20 CBY35095.1 - 0.089 12.9 0.2 0.089 12.9 0.2 3.4 3 1 0 3 3 3 0 DHHC palmitoyltransferase EphA2_TM PF14575.6 CBY35095.1 - 0.13 13.1 0.7 1.9 9.4 0.0 3.1 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain OAD_gamma PF04277.13 CBY35095.1 - 1.6 9.4 6.4 24 5.6 0.3 3.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TssO PF17561.2 CBY35095.1 - 6.4 6.9 9.3 0.14 12.3 1.1 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO DOMON PF03351.17 CBY35097.1 - 0.00051 20.2 0.6 0.0028 17.9 0.6 2.0 1 1 0 1 1 1 1 DOMON domain DUF2407_C PF13373.6 CBY35097.1 - 0.24 11.6 1.9 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2427 PF10348.9 CBY35097.1 - 9 6.1 11.0 0.32 10.8 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Forkhead PF00250.18 CBY35098.1 - 2.1e-37 127.3 0.2 4.4e-37 126.2 0.0 1.7 2 0 0 2 2 2 1 Forkhead domain B56 PF01603.20 CBY35099.1 - 1.3e-141 472.4 9.5 1.6e-141 472.1 9.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) XPC-binding PF09280.11 CBY35099.1 - 0.013 15.2 0.4 0.05 13.3 0.4 2.1 1 0 0 1 1 1 0 XPC-binding domain ArsC PF03960.15 CBY35099.1 - 0.075 13.1 0.2 0.24 11.4 0.2 1.8 1 0 0 1 1 1 0 ArsC family Sec7_N PF12783.7 CBY35099.1 - 0.082 12.8 4.2 6.5 6.6 0.0 3.5 2 2 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3449 PF11931.8 CBY35100.1 - 0.029 14.2 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF2439 PF10382.9 CBY35101.1 - 3.8e-08 33.5 0.0 8.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Aa_trans PF01490.18 CBY35102.1 - 1.3e-24 86.6 5.0 1.7e-24 86.3 4.7 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein COX15-CtaA PF02628.15 CBY35102.1 - 0.035 13.2 1.2 0.32 10.0 1.8 1.9 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein eIF-5_eIF-2B PF01873.17 CBY35103.1 - 6.3e-40 135.7 0.2 1.3e-39 134.7 0.2 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Antimicrobial_6 PF08036.11 CBY35103.1 - 0.034 14.2 0.5 0.074 13.1 0.5 1.5 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Staphostatin_B PF09023.10 CBY35104.1 - 0.054 13.5 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphostatin B Dynactin_p62 PF05502.13 CBY35105.1 - 2.6e-27 95.8 7.0 2.4e-15 56.3 0.1 2.1 2 0 0 2 2 2 2 Dynactin p62 family SAND PF01342.21 CBY35106.1 - 9.7e-16 57.3 0.4 9.7e-16 57.3 0.4 1.8 2 0 0 2 2 2 1 SAND domain zf-MYND PF01753.18 CBY35106.1 - 4.8e-06 26.6 17.3 4.8e-06 26.6 17.3 2.3 2 0 0 2 2 2 1 MYND finger CdvA PF18822.1 CBY35106.1 - 0.0003 20.6 0.6 0.00049 19.9 0.6 1.3 1 0 0 1 1 1 1 CdvA-like coiled-coil domain DUF4600 PF15372.6 CBY35106.1 - 0.027 14.9 1.5 0.19 12.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4407 PF14362.6 CBY35106.1 - 0.1 11.9 1.8 0.16 11.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase_Tyr PF07714.17 CBY35107.1 - 1.2e-56 191.9 0.0 6.2e-52 176.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY35107.1 - 7.5e-31 107.5 0.0 1.2e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY35107.1 - 0.031 13.2 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY35107.1 - 0.039 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAW PF04721.17 CBY35108.1 - 3.9e-41 141.0 0.2 3.9e-41 141.0 0.2 1.9 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 CBY35108.1 - 1.1e-17 63.7 0.0 3.5e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 CBY35108.1 - 6.5e-06 26.6 0.2 2.3e-05 24.8 0.2 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily PrmA PF06325.13 CBY35108.1 - 0.077 12.4 2.1 0.18 11.1 0.7 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Lipocalin_7 PF14651.6 CBY35109.1 - 0.0067 16.4 1.3 0.0072 16.3 1.3 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Peptidase_M2 PF01401.18 CBY35110.1 - 1.6e-167 558.6 1.9 1.8e-167 558.4 1.9 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF3439 PF11921.8 CBY35110.1 - 0.052 13.5 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kazal_2 PF07648.15 CBY35112.1 - 0.00019 21.5 0.6 0.00019 21.5 0.6 2.6 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY35112.1 - 0.0095 15.9 0.9 0.026 14.6 0.1 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Mid2 PF04478.12 CBY35112.1 - 0.061 13.1 0.4 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor zf-C2H2 PF00096.26 CBY35113.1 - 1.8e-12 47.0 32.8 0.02 15.3 0.2 6.6 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY35113.1 - 5.6e-09 36.1 18.6 0.04 14.2 3.3 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY35113.1 - 8.4e-09 35.5 29.7 1.6e-06 28.3 0.7 6.1 6 0 0 6 6 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY35113.1 - 6.6e-08 32.8 35.6 0.011 16.4 0.4 6.9 7 0 0 7 7 6 4 C2H2-type zinc finger zf-Di19 PF05605.12 CBY35113.1 - 1.3e-07 31.8 18.8 0.00025 21.3 1.5 4.5 4 1 1 5 5 5 3 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY35113.1 - 5.6e-06 26.6 20.5 0.0021 18.4 0.7 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CBY35113.1 - 0.00022 21.9 18.9 1.4 9.6 0.5 6.0 2 1 4 6 6 6 2 Zinc finger C2H2-type, 3 repeats FYVE PF01363.21 CBY35113.1 - 0.00069 19.7 5.1 5.2 7.3 1.5 4.5 3 1 0 3 3 3 2 FYVE zinc finger zf-H2C2_5 PF13909.6 CBY35113.1 - 0.00084 19.0 2.6 0.012 15.3 1.0 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 CBY35113.1 - 0.0059 16.4 0.1 0.018 14.9 0.1 1.9 1 0 0 1 1 1 1 Rad50 zinc hook motif GAGA PF09237.11 CBY35113.1 - 0.016 15.0 10.3 1.6 8.6 0.1 3.9 4 1 0 4 4 3 0 GAGA factor zf-C2H2_2 PF12756.7 CBY35113.1 - 0.026 14.9 30.5 0.035 14.4 2.0 5.4 2 1 4 6 6 5 0 C2H2 type zinc-finger (2 copies) TPMT PF05724.11 CBY35113.1 - 0.039 13.6 0.1 0.1 12.2 0.0 1.7 1 1 1 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Zn-ribbon_8 PF09723.10 CBY35113.1 - 0.045 13.9 2.2 0.045 13.9 2.2 4.2 3 1 0 3 3 3 0 Zinc ribbon domain WAC_Acf1_DNA_bd PF10537.9 CBY35113.1 - 0.18 12.4 1.7 11 6.6 0.0 3.0 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal zf-C2H2_9 PF16293.5 CBY35113.1 - 0.36 10.7 12.5 8.8 6.3 0.1 5.6 5 1 1 6 6 6 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 CBY35113.1 - 0.68 9.6 21.1 0.64 9.7 0.1 5.0 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 CBY35113.1 - 1.2 9.5 7.4 2 8.8 0.1 2.9 3 0 0 3 3 3 0 zinc-finger-containing domain c-SKI_SMAD_bind PF08782.10 CBY35113.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.8 4 1 1 5 5 5 0 c-SKI Smad4 binding domain zf-C2HE PF16278.5 CBY35113.1 - 1.9 9.0 21.5 1.2 9.6 1.4 4.4 3 1 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 CBY35113.1 - 2.1 8.6 8.6 37 4.5 0.3 4.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_6 PF13912.6 CBY35113.1 - 7.8 6.6 33.6 0.69 10.0 0.4 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger Pkinase PF00069.25 CBY35115.1 - 7.8e-60 202.5 1.1 1.8e-58 198.0 0.0 3.0 4 0 0 4 4 4 1 Protein kinase domain cNMP_binding PF00027.29 CBY35115.1 - 3e-37 126.6 0.2 6.4e-19 67.8 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY35115.1 - 3e-27 95.5 0.0 2.1e-26 92.8 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY35115.1 - 8.7e-05 22.0 0.3 0.00019 20.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CBY35115.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CBY35115.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHDCT2 PF08074.11 CBY35115.1 - 0.14 12.3 7.3 0.41 10.8 7.3 1.8 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain V_ATPase_I PF01496.19 CBY35115.1 - 0.25 9.2 10.7 0.39 8.6 10.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 CBY35115.1 - 0.64 10.1 2.9 1.8 8.6 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4407 PF14362.6 CBY35115.1 - 2.2 7.6 13.9 4.3 6.6 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 CBY35115.1 - 4.4 7.4 22.4 3.8 7.5 15.9 2.7 1 1 1 2 2 2 0 FlxA-like protein Ets PF00178.22 CBY35117.1 - 2.1e-35 121.1 1.0 2.1e-35 121.1 1.0 1.7 2 0 0 2 2 2 1 Ets-domain SAM_PNT PF02198.16 CBY35117.1 - 5.2e-13 48.8 0.3 1.1e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Lyase_aromatic PF00221.19 CBY35118.1 - 1.2e-174 581.4 0.2 1.3e-174 581.2 0.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Zona_pellucida PF00100.23 CBY35119.1 - 6.6e-11 42.5 0.0 9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Med17 PF10156.9 CBY35122.1 - 0.25 10.0 1.7 0.36 9.5 1.7 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Imm35 PF15567.6 CBY35123.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 2 0 0 2 2 2 0 Immunity protein 35 L6_membrane PF05805.12 CBY35123.1 - 2.2 7.8 3.7 2.7 7.5 0.6 1.9 1 1 1 2 2 2 0 L6 membrane protein Methyltransf_31 PF13847.6 CBY35124.1 - 8.7e-29 100.3 0.0 1.7e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY35124.1 - 2e-18 66.9 0.1 3.8e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY35124.1 - 2e-17 63.6 0.0 4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY35124.1 - 2.3e-15 56.6 0.0 3.2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBY35124.1 - 7.1e-12 45.9 0.1 1.7e-11 44.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY35124.1 - 6.5e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY35124.1 - 4.3e-07 29.9 0.1 1.2e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 CBY35124.1 - 0.00036 20.5 0.2 0.052 13.4 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.13 CBY35124.1 - 0.00071 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBY35124.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CBY35124.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Fibrillarin PF01269.17 CBY35124.1 - 0.015 14.4 0.0 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin MTS PF05175.14 CBY35124.1 - 0.02 14.4 0.1 0.077 12.5 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.17 CBY35124.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.17 CBY35124.1 - 0.066 12.7 0.0 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.19 CBY35124.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 CBY35124.1 - 0.13 10.7 0.4 0.21 10.1 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ins145_P3_rec PF08709.11 CBY35125.1 - 2.6e-83 278.4 0.0 3.1e-82 274.9 0.0 2.4 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 CBY35125.1 - 8.3e-60 201.7 28.8 1.7e-50 171.3 8.0 3.8 3 0 0 3 3 3 2 RIH domain MIR PF02815.19 CBY35125.1 - 5.5e-52 176.3 0.8 2.1e-47 161.4 0.0 3.7 3 0 0 3 3 3 2 MIR domain RIH_assoc PF08454.11 CBY35125.1 - 3.6e-32 110.2 8.9 8.1e-32 109.1 2.5 4.1 2 0 0 2 2 2 1 RyR and IP3R Homology associated Clat_adaptor_s PF01217.20 CBY35126.1 - 2.9e-17 62.9 3.7 5.7e-17 62.0 3.7 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ank_5 PF13857.6 CBY35127.1 - 7.3e-23 80.3 0.3 5.8e-09 36.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY35127.1 - 9.8e-23 80.2 0.2 5.1e-11 42.9 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35127.1 - 1.2e-22 80.3 0.1 2.3e-12 47.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY35127.1 - 2.6e-16 59.2 0.1 1.7e-08 34.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBY35127.1 - 4.7e-12 45.0 0.0 3.8e-05 23.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Neuralized PF07177.12 CBY35128.1 - 1.1e-25 90.4 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Neuralized MRP-63 PF14978.6 CBY35129.1 - 1e-05 26.0 0.7 0.00028 21.4 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial ribosome protein 63 7tm_1 PF00001.21 CBY35130.1 - 5.6e-32 111.1 12.9 1.7e-16 60.4 3.6 2.4 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) YIEGIA PF14045.6 CBY35130.1 - 0.024 13.5 1.1 0.026 13.4 0.0 1.5 2 0 0 2 2 2 0 YIEGIA protein Chromo PF00385.24 CBY35131.1 - 4.1e-24 84.2 10.1 1.1e-11 44.4 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 CBY35131.1 - 0.00099 18.7 23.1 0.097 12.6 4.1 4.4 2 1 1 3 3 3 3 AT hook motif Tudor-knot PF11717.8 CBY35131.1 - 0.0019 18.1 6.3 0.16 11.9 0.1 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 CBY35131.1 - 0.062 13.5 0.9 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 GIY-YIG PF01541.24 CBY35131.1 - 0.17 12.2 4.5 0.55 10.5 4.5 1.8 1 0 0 1 1 1 0 GIY-YIG catalytic domain zf-H2C2_2 PF13465.6 CBY35132.1 - 4.7e-09 36.3 35.3 0.00071 19.9 10.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY35132.1 - 1.5e-06 28.3 34.5 0.005 17.2 8.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35132.1 - 4.6e-06 27.0 30.1 0.033 15.0 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY35132.1 - 0.0048 16.9 4.8 0.0048 16.9 4.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 CBY35132.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF1966 PF09260.11 CBY35132.1 - 0.15 12.3 0.5 0.37 11.1 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-met PF12874.7 CBY35132.1 - 0.27 11.7 15.3 1 9.9 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Acyltransf_C PF16076.5 CBY35132.1 - 0.35 11.0 2.6 11 6.2 0.0 3.0 2 1 1 3 3 3 0 Acyltransferase C-terminus PyrI_C PF02748.15 CBY35132.1 - 1.2 9.1 11.9 1.7 8.6 0.3 3.5 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ALMS_motif PF15309.6 CBY35132.1 - 1.2 9.6 6.8 14 6.2 1.3 2.7 2 0 0 2 2 2 0 ALMS motif zf-CHY PF05495.12 CBY35132.1 - 1.4 9.5 16.5 2.6 8.6 16.5 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_jaz PF12171.8 CBY35132.1 - 1.5 9.2 14.2 0.66 10.3 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CBY35132.1 - 1.8 8.7 16.4 1.6 8.9 0.9 3.4 1 1 2 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 CBY35132.1 - 1.8 8.5 23.7 0.99 9.4 1.6 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 CBY35132.1 - 8.9 6.5 15.1 0.34 11.0 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C4 PF00105.18 CBY35134.1 - 3.1e-27 94.8 22.7 5.5e-27 94.0 22.7 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY35134.1 - 4.5e-10 39.4 2.1 8.2e-10 38.6 2.1 1.4 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor DDA1 PF10172.9 CBY35134.1 - 0.028 14.7 0.2 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase HoxA13_N PF12284.8 CBY35134.1 - 0.082 13.5 0.9 0.22 12.1 0.9 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal EGF_2 PF07974.13 CBY35136.1 - 6.1e-13 48.9 96.1 0.00014 22.1 14.7 6.7 6 0 0 6 6 6 6 EGF-like domain EGF PF00008.27 CBY35136.1 - 1.1e-05 25.6 66.7 0.0038 17.5 5.1 6.7 6 0 0 6 6 6 4 EGF-like domain RHS_repeat PF05593.14 CBY35136.1 - 0.0036 17.8 0.6 6.2 7.4 0.0 4.8 6 0 0 6 6 6 1 RHS Repeat DUF3333 PF11812.8 CBY35136.1 - 0.016 15.4 0.1 0.03 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) SspH PF08141.12 CBY35136.1 - 0.06 13.5 1.4 9.3 6.5 0.0 3.7 3 0 0 3 3 3 0 Small acid-soluble spore protein H family MORN_2 PF07661.13 CBY35136.1 - 0.3 11.4 3.0 15 6.2 0.0 4.7 5 0 0 5 5 5 0 MORN repeat variant Sugar_tr PF00083.24 CBY35137.1 - 1.4e-10 40.7 8.1 1.9e-10 40.2 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35137.1 - 1.4e-07 30.7 15.5 3.5e-07 29.5 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY35138.1 - 7e-12 44.9 0.6 9e-12 44.6 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35138.1 - 1e-10 41.1 0.5 1.2e-10 40.9 0.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY35139.1 - 9.1e-10 38.0 5.4 5e-05 22.3 0.2 2.4 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY35139.1 - 0.024 13.6 13.6 0.043 12.7 0.9 2.4 2 1 1 3 3 3 0 Major Facilitator Superfamily Coiled-coil_56 PF09813.9 CBY35139.1 - 0.14 12.2 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 TetR_C_23 PF17931.1 CBY35140.1 - 0.061 13.4 3.3 0.097 12.8 0.8 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LON_substr_bdg PF02190.16 CBY35140.1 - 0.37 10.6 2.3 0.82 9.5 2.3 1.6 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain AhpC-TSA_2 PF13911.6 CBY35141.1 - 1.7e-14 53.9 0.1 2.3e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CBY35141.1 - 3e-07 30.4 0.0 5.5e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY35141.1 - 0.00097 18.9 0.1 0.0075 16.0 0.1 2.1 1 1 0 1 1 1 1 Redoxin DUF1805 PF08827.11 CBY35141.1 - 0.088 13.2 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Asp-Al_Ex PF06826.12 CBY35143.1 - 0.11 12.3 0.3 0.15 11.9 0.3 1.1 1 0 0 1 1 1 0 Predicted Permease Membrane Region Sec7 PF01369.20 CBY35144.1 - 5.2e-59 199.0 1.1 1.3e-58 197.7 0.3 2.1 2 0 0 2 2 2 1 Sec7 domain IQ_SEC7_PH PF16453.5 CBY35144.1 - 1.5e-49 167.5 0.1 3.9e-49 166.2 0.1 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 CBY35144.1 - 0.0032 18.0 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CBY35144.1 - 5.9 7.0 8.5 0.49 10.3 1.4 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif RRM_1 PF00076.22 CBY35146.1 - 1.5e-16 59.9 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY35146.1 - 0.00011 21.8 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CBY35146.1 - 0.0028 17.8 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 RRM-like domain RRM_7 PF16367.5 CBY35146.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif zf-CHCC PF10276.9 CBY35147.1 - 3.9e-16 58.8 1.6 5.8e-16 58.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain RimK PF08443.11 CBY35147.1 - 0.072 12.7 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain COX5B PF01215.19 CBY35147.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Golgin_A5 PF09787.9 CBY35148.1 - 0.00018 21.1 6.4 0.00021 20.8 6.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Paralemmin PF03285.15 CBY35148.1 - 0.0045 16.6 3.8 0.0065 16.1 3.8 1.2 1 0 0 1 1 1 1 Paralemmin ABC_tran_CTD PF16326.5 CBY35148.1 - 0.011 15.9 9.8 0.1 12.9 0.8 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain ERM PF00769.19 CBY35148.1 - 0.031 14.1 8.1 0.042 13.7 8.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TssR PF17643.1 CBY35148.1 - 0.049 11.6 0.2 0.054 11.4 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR V-SNARE PF05008.15 CBY35148.1 - 0.063 13.7 3.3 0.072 13.5 0.9 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus betaPIX_CC PF16523.5 CBY35148.1 - 0.074 12.9 2.9 0.13 12.1 1.1 2.1 1 1 1 2 2 2 0 betaPIX coiled coil FlxA PF14282.6 CBY35148.1 - 0.087 12.8 3.5 0.16 11.9 3.5 1.4 1 0 0 1 1 1 0 FlxA-like protein ZapA PF05164.13 CBY35148.1 - 0.13 12.7 2.8 0.23 11.9 2.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapA Fez1 PF06818.15 CBY35148.1 - 0.13 12.7 8.0 0.17 12.3 8.0 1.1 1 0 0 1 1 1 0 Fez1 DUF4910 PF16254.5 CBY35148.1 - 0.15 10.9 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) Cep57_MT_bd PF06657.13 CBY35148.1 - 0.48 10.9 7.9 0.78 10.2 3.7 2.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2408 PF10303.9 CBY35148.1 - 0.69 10.5 5.4 1.4 9.5 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Fzo_mitofusin PF04799.13 CBY35148.1 - 4 7.0 5.7 3.4 7.2 3.9 1.8 2 1 1 3 3 3 0 fzo-like conserved region PRP1_N PF06424.12 CBY35149.1 - 8e-56 188.6 4.3 9.3e-56 188.3 4.3 1.0 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal FAM76 PF16046.5 CBY35153.1 - 0.0055 16.1 21.1 0.0055 16.1 21.1 3.0 3 0 0 3 3 3 1 FAM76 protein Phage_P2_GpU PF06995.11 CBY35154.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage P2 GpU Neprosin_AP PF14365.6 CBY35154.1 - 0.33 11.4 5.6 0.83 10.2 0.7 2.4 2 0 0 2 2 2 0 Neprosin activation peptide Glycos_transf_1 PF00534.20 CBY35155.1 - 6.5e-12 45.3 0.0 7.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY35155.1 - 4e-05 24.1 0.0 6.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBY35155.1 - 0.083 13.3 0.0 0.094 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY35156.1 - 1.2e-11 44.9 0.1 3.2e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CBY35156.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBY35156.1 - 0.00083 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3021 PF11457.8 CBY35156.1 - 0.075 13.4 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) RNase_Zc3h12a PF11977.8 CBY35157.1 - 2e-28 99.1 0.0 3.5e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.6 CBY35157.1 - 0.0022 18.3 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 2 Periplasmic binding protein-like domain XPG_I PF00867.18 CBY35158.1 - 3.1e-14 53.1 1.3 7.3e-13 48.7 0.0 3.8 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CBY35158.1 - 0.0015 19.1 0.0 0.0015 19.1 0.0 3.8 4 0 0 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold DUF1344 PF07076.11 CBY35158.1 - 0.034 14.0 0.2 0.3 11.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) STI1 PF17830.1 CBY35159.1 - 0.00047 20.0 0.3 0.32 10.9 0.0 2.6 2 0 0 2 2 2 2 STI1 domain CDC27 PF09507.10 CBY35159.1 - 4.4 6.6 18.2 9.7 5.5 18.3 1.5 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_D5 PF03288.16 CBY35160.1 - 7.2 7.2 8.9 1 9.9 1.0 2.7 2 1 0 2 2 2 0 Poxvirus D5 protein-like IBN_N PF03810.19 CBY35161.1 - 3.7e-11 42.8 0.0 4.1e-10 39.4 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBY35161.1 - 1.4e-05 25.2 5.1 5.1e-05 23.4 0.0 3.9 3 2 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 CBY35161.1 - 0.00013 21.9 0.4 19 5.8 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat MMS19_C PF12460.8 CBY35161.1 - 0.0016 17.6 0.5 1.7 7.7 0.0 3.1 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal DCB PF16213.5 CBY35161.1 - 0.01 15.5 0.0 0.18 11.5 0.0 2.8 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SPDY PF03771.16 CBY35161.1 - 0.052 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF2729 PF10870.8 CBY35161.1 - 8.3 6.4 7.1 0.33 10.8 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2729) Synaptobrevin PF00957.21 CBY35162.1 - 6.4e-31 106.0 4.1 7.2e-31 105.8 4.1 1.0 1 0 0 1 1 1 1 Synaptobrevin CEND1 PF15677.5 CBY35162.1 - 0.013 16.0 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Foamy_virus_ENV PF03408.14 CBY35162.1 - 0.015 13.2 0.0 0.015 13.2 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein ASFV_J13L PF05568.11 CBY35162.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Asp5 PF17000.5 CBY35162.1 - 0.028 14.6 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 ODV-E18 PF10717.9 CBY35162.1 - 0.032 14.1 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CD34_antigen PF06365.12 CBY35162.1 - 0.034 13.7 0.2 0.041 13.4 0.2 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family MCU PF04678.13 CBY35162.1 - 0.044 13.9 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Sigma_reg_N PF13800.6 CBY35162.1 - 0.066 13.5 0.6 0.12 12.7 0.6 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SP_C-Propep PF08999.10 CBY35162.1 - 0.066 13.0 0.6 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Fzo_mitofusin PF04799.13 CBY35162.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region RIFIN PF02009.16 CBY35162.1 - 0.081 12.8 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 Rifin Orf78 PF06024.12 CBY35162.1 - 0.13 12.6 1.2 0.18 12.1 1.2 1.3 1 1 0 1 1 1 0 Orf78 (ac78) Glycophorin_A PF01102.18 CBY35162.1 - 0.15 12.3 0.9 0.19 11.9 0.9 1.4 1 1 0 1 1 1 0 Glycophorin A ECSCR PF15820.5 CBY35162.1 - 0.25 11.2 3.2 0.5 10.2 1.9 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator FeoB_associated PF12669.7 CBY35162.1 - 0.29 11.6 2.1 0.47 10.9 2.1 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2937 PF11157.8 CBY35162.1 - 0.43 10.3 3.5 0.17 11.5 1.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) XhlA PF10779.9 CBY35162.1 - 0.66 10.2 5.8 2.3 8.5 5.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA GP41 PF00517.17 CBY35162.1 - 0.83 9.5 8.2 3.6 7.4 8.2 1.8 1 1 0 1 1 1 0 Retroviral envelope protein RanGAP1_C PF07834.11 CBY35163.1 - 0.00052 19.7 0.0 0.0006 19.5 0.0 1.1 1 0 0 1 1 1 1 RanGAP1 C-terminal domain T-box PF00907.22 CBY35164.1 - 7.2e-74 248.0 0.2 9.1e-74 247.7 0.2 1.1 1 0 0 1 1 1 1 T-box GTP_EFTU PF00009.27 CBY35166.1 - 0.05 13.1 0.0 0.42 10.1 0.0 2.3 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain ACP_PD PF04336.12 CBY35166.1 - 0.097 13.1 0.5 5.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase TcdB_N PF12918.7 CBY35167.1 - 0.0073 16.6 19.5 0.48 10.8 0.2 5.4 4 1 0 5 5 5 1 TcdB toxin N-terminal helical domain RPAP1_N PF08621.10 CBY35167.1 - 0.014 15.2 22.5 0.049 13.4 3.1 4.4 4 0 0 4 4 4 0 RPAP1-like, N-terminal Cas_DxTHG PF09455.10 CBY35167.1 - 0.014 15.0 16.1 0.017 14.7 16.1 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family NPV_P10 PF05531.12 CBY35167.1 - 0.1 13.1 4.2 11 6.6 0.1 4.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein YfbU PF03887.14 CBY35167.1 - 0.22 11.5 9.2 0.37 10.8 9.1 1.6 1 1 0 1 1 1 0 YfbU domain TERF2_RBM PF16772.5 CBY35167.1 - 0.34 10.3 2.5 14 5.2 0.0 3.4 3 0 0 3 3 3 0 Telomeric repeat-binding factor 2 Rap1-binding motif FUSC PF04632.12 CBY35167.1 - 0.57 8.6 3.4 0.32 9.5 0.2 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Bindin PF02084.15 CBY35167.1 - 0.75 10.0 6.1 0.2 11.9 2.4 2.0 1 1 1 2 2 2 0 Bindin ComX PF05952.12 CBY35167.1 - 3 7.9 6.8 26 4.8 0.1 3.9 4 1 1 5 5 5 0 Bacillus competence pheromone ComX DUF1690 PF07956.11 CBY35167.1 - 3.5 8.1 31.5 0.55 10.7 13.2 3.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) COX4 PF02936.14 CBY35167.1 - 4.3 7.4 16.3 0.11 12.5 5.5 3.2 1 1 2 3 3 3 0 Cytochrome c oxidase subunit IV Metal_resist PF13801.6 CBY35167.1 - 4.8 7.4 0.0 4.8 7.4 0.0 4.7 1 1 3 4 4 3 0 Heavy-metal resistance RPAP1_N PF08621.10 CBY35168.1 - 0.023 14.5 2.1 0.054 13.3 2.1 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal HSBP1 PF06825.12 CBY35168.1 - 0.026 14.4 3.7 0.3 11.0 3.5 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Aminopep PF10023.9 CBY35168.1 - 0.028 13.8 0.2 0.029 13.7 0.2 1.2 1 0 0 1 1 1 0 Putative aminopeptidase DUF1104 PF06518.11 CBY35168.1 - 0.033 14.6 8.6 0.053 13.9 8.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) PhageMin_Tail PF10145.9 CBY35168.1 - 0.039 13.8 5.5 0.45 10.3 5.5 2.0 1 1 0 1 1 1 0 Phage-related minor tail protein Rho_Binding PF08912.11 CBY35168.1 - 0.082 13.7 4.8 0.1 13.4 4.5 1.3 1 1 0 1 1 1 0 Rho Binding SRP_SPB PF02978.19 CBY35168.1 - 0.11 13.1 5.1 0.39 11.4 5.1 1.8 1 1 0 1 1 1 0 Signal peptide binding domain XhlA PF10779.9 CBY35168.1 - 0.58 10.4 3.5 0.85 9.9 3.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Abhydrolase_6 PF12697.7 CBY35169.1 - 1e-16 62.2 0.0 1.3e-16 61.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY35169.1 - 2e-07 31.4 0.1 0.00012 22.2 0.0 2.7 3 0 0 3 3 3 2 Thioesterase domain Abhydrolase_1 PF00561.20 CBY35169.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY35169.1 - 3.7e-05 23.1 0.0 0.00017 20.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 CBY35169.1 - 0.00057 19.0 0.0 0.0024 17.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 CBY35169.1 - 0.017 14.9 0.1 0.33 10.7 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CBY35169.1 - 0.04 13.5 0.0 0.091 12.3 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 CBY35169.1 - 0.054 12.4 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 CBY35169.1 - 0.096 12.5 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Troponin PF00992.20 CBY35170.1 - 5.7e-20 72.0 36.9 5.1e-16 59.2 29.7 2.0 1 1 1 2 2 2 2 Troponin CENP-F_leu_zip PF10473.9 CBY35170.1 - 0.039 14.0 1.6 0.039 14.0 1.6 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CBY35170.1 - 0.041 14.3 1.5 0.041 14.3 1.5 3.6 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 CBY35170.1 - 0.12 13.0 0.4 0.12 13.0 0.4 2.9 2 1 0 2 2 2 0 Initiation control protein YabA Lipocalin_2 PF08212.12 CBY35171.1 - 3e-14 53.2 0.0 3.9e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY35171.1 - 0.0002 21.6 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family CH PF00307.31 CBY35172.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF4770 PF15994.5 CBY35172.1 - 0.16 12.2 1.4 0.3 11.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EGF_CA PF07645.15 CBY35174.1 - 5.3e-24 84.1 51.5 3.3e-09 36.8 6.6 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain hEGF PF12661.7 CBY35174.1 - 1.3e-06 28.8 36.5 0.0082 16.7 4.5 5.3 4 1 0 4 4 4 4 Human growth factor-like EGF cEGF PF12662.7 CBY35174.1 - 5.4e-06 26.2 0.6 5.4e-06 26.2 0.6 5.5 5 1 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY35174.1 - 5.2e-05 23.3 55.3 0.022 15.0 7.1 5.2 6 0 0 6 6 6 4 EGF domain FXa_inhibition PF14670.6 CBY35174.1 - 0.00062 20.0 48.2 0.071 13.4 2.6 4.6 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY35174.1 - 0.00075 19.7 7.1 0.00075 19.7 7.1 4.8 4 0 0 4 4 4 3 EGF-like domain Spa1_C PF18218.1 CBY35175.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 1 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain Peptidase_S28 PF05577.12 CBY35176.1 - 2.2e-67 227.7 0.0 3e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 CBY35176.1 - 2.4e-05 23.2 0.0 3.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 CBY35176.1 - 2.9e-05 23.4 0.0 4.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY35176.1 - 4.6e-05 24.1 0.1 0.00078 20.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY35176.1 - 9.7e-05 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY35176.1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 CBY35176.1 - 0.14 11.3 0.3 0.21 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) zf-Tim10_DDP PF02953.15 CBY35177.1 - 3e-12 46.0 11.1 3e-12 46.0 11.1 1.9 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF629 PF04780.12 CBY35177.1 - 0.019 13.5 5.2 0.019 13.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Aa_trans PF01490.18 CBY35178.1 - 3.6e-35 121.5 6.9 4.7e-35 121.1 6.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2448 PF10476.9 CBY35178.1 - 0.058 13.2 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DUF1772 PF08592.11 CBY35178.1 - 1.3 9.4 11.5 0.65 10.3 4.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4217 PF13959.6 CBY35179.1 - 4.7e-14 52.4 0.1 8.3e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Ribosomal_S13 PF00416.22 CBY35179.1 - 0.033 14.6 0.9 0.12 12.7 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Helicase_C PF00271.31 CBY35179.1 - 0.065 13.6 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ferritin PF00210.24 CBY35180.1 - 1.2e-18 67.4 0.8 9.6e-18 64.5 0.6 1.9 1 1 0 2 2 2 1 Ferritin-like domain Rubrerythrin PF02915.17 CBY35180.1 - 1.7e-06 28.5 0.8 2.8e-06 27.8 0.8 1.4 1 0 0 1 1 1 1 Rubrerythrin FCH PF00611.23 CBY35180.1 - 0.21 11.9 1.1 0.85 9.9 0.3 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Isochorismatase PF00857.20 CBY35181.1 - 4e-23 82.5 0.2 5.7e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 Isochorismatase family MAF_flag10 PF01973.18 CBY35181.1 - 0.048 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 zf-C3HC4_3 PF13920.6 CBY35182.1 - 1.3e-07 31.4 8.1 2.4e-07 30.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY35182.1 - 1.2e-06 28.3 10.1 2.3e-06 27.3 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY35182.1 - 9.6e-06 25.3 10.7 2.1e-05 24.3 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY35182.1 - 2.9e-05 24.3 10.2 6e-05 23.3 10.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBY35182.1 - 0.0022 17.9 9.6 0.0061 16.5 9.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBY35182.1 - 0.053 13.8 8.7 0.21 11.9 8.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBY35182.1 - 0.11 12.7 9.5 0.42 10.8 9.5 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBY35182.1 - 0.32 11.1 9.0 0.43 10.7 6.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBY35182.1 - 0.79 9.8 4.8 1.5 9.0 4.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBY35182.1 - 1.1 9.2 9.7 4.4 7.2 9.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YdjO PF14169.6 CBY35182.1 - 1.5 8.6 3.8 1.1 9.1 0.3 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-Nse PF11789.8 CBY35182.1 - 2 8.3 6.5 5.1 7.0 6.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sec15 PF04091.12 CBY35183.1 - 2.1e-47 162.1 0.7 1.9e-46 159.0 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 CBY35183.1 - 0.0069 16.6 1.1 0.0069 16.6 1.1 2.9 2 1 0 2 2 2 1 Golgi transport complex subunit 5 DUF592 PF04574.13 CBY35183.1 - 0.035 13.9 0.3 0.035 13.9 0.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF592) Sec8_exocyst PF04048.14 CBY35183.1 - 0.31 10.9 8.6 0.34 10.8 1.2 3.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain TnpV PF14198.6 CBY35183.1 - 0.37 10.8 9.6 0.21 11.6 0.4 3.6 3 1 0 3 3 3 0 Transposon-encoded protein TnpV WD40 PF00400.32 CBY35184.1 - 3e-12 46.9 9.8 7.3e-05 23.5 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35184.1 - 5.5e-08 33.0 1.1 2.5e-06 27.7 0.2 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY35184.1 - 6.6e-05 21.7 1.6 0.00055 18.7 0.9 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CBY35184.1 - 0.00063 19.2 1.3 0.0035 16.7 0.1 2.4 2 1 1 3 3 3 1 WD40-like domain eIF2A PF08662.11 CBY35184.1 - 0.00076 19.4 0.5 0.12 12.3 0.1 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Utp8 PF10395.9 CBY35184.1 - 0.0096 14.5 0.1 0.64 8.4 0.0 2.0 1 1 1 2 2 2 2 Utp8 family Vps16_N PF04841.13 CBY35184.1 - 0.015 14.1 0.2 0.022 13.5 0.2 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Nucleoporin_N PF08801.11 CBY35184.1 - 0.082 11.6 0.1 5 5.7 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Hira PF07569.11 CBY35184.1 - 0.2 11.4 4.7 2.5 7.8 3.1 2.7 1 1 1 2 2 2 0 TUP1-like enhancer of split Mito_carr PF00153.27 CBY35185.1 - 5.1e-19 68.0 1.3 1.4e-12 47.4 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein DHC_N1 PF08385.12 CBY35186.1 - 1.3e-138 463.2 6.2 1.7e-138 462.8 6.2 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 SieB PF14163.6 CBY35186.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Sulfate_transp PF00916.20 CBY35188.1 - 7.4e-45 153.3 3.1 8.8e-45 153.1 3.1 1.0 1 0 0 1 1 1 1 Sulfate permease family La PF05383.17 CBY35190.1 - 1.5e-14 53.8 0.1 2.8e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY35190.1 - 0.0005 19.8 0.1 0.0039 17.0 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 CBY35191.1 - 4e-38 132.0 0.0 5.1e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rap_GAP PF02145.15 CBY35192.1 - 0.028 14.0 0.6 0.073 12.6 0.1 2.0 2 0 0 2 2 2 0 Rap/ran-GAP Sugar_tr PF00083.24 CBY35193.1 - 7.4e-18 64.6 0.6 1e-17 64.2 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35193.1 - 2e-14 53.3 1.3 2e-14 53.3 1.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily IL3Ra_N PF18611.1 CBY35193.1 - 0.039 13.9 1.4 0.27 11.3 2.0 2.1 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain DUF1275 PF06912.11 CBY35193.1 - 1.7 8.5 9.6 0.67 9.8 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1275) Sugar_tr PF00083.24 CBY35194.1 - 1.5e-09 37.3 9.7 1.9e-09 36.9 9.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35194.1 - 1.9e-08 33.7 13.6 2.6e-08 33.2 13.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1440 PF07274.12 CBY35194.1 - 0.031 14.6 0.3 0.031 14.6 0.3 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1440) DUF1053 PF06327.14 CBY35195.1 - 0.04 14.5 0.9 0.17 12.4 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF4202 PF13875.6 CBY35196.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Halogen_Hydrol PF10112.9 CBY35197.1 - 0.0064 16.5 3.2 0.057 13.4 0.0 2.6 3 0 0 3 3 3 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1326 PF07040.11 CBY35197.1 - 0.043 13.8 0.5 0.083 12.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1326) Kri1 PF05178.12 CBY35197.1 - 0.11 13.1 3.7 0.33 11.5 3.7 1.8 1 0 0 1 1 1 0 KRI1-like family Ion_trans_2 PF07885.16 CBY35198.1 - 1.9e-30 104.6 15.8 3.5e-16 58.9 1.6 3.2 3 0 0 3 3 3 3 Ion channel Ion_trans PF00520.31 CBY35198.1 - 0.0031 16.8 0.5 0.0031 16.8 0.5 2.9 3 1 0 3 3 3 1 Ion transport protein IRK PF01007.20 CBY35198.1 - 0.017 14.9 3.4 0.89 9.4 0.1 3.0 3 0 0 3 3 3 0 Inward rectifier potassium channel transmembrane domain I-set PF07679.16 CBY35199.1 - 6.1e-26 90.3 0.0 3.8e-18 65.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY35199.1 - 1.7e-20 73.4 0.0 1.2e-13 51.5 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain fn3 PF00041.21 CBY35199.1 - 4.5e-20 71.8 0.4 1.4e-11 44.6 0.2 2.7 2 0 0 2 2 2 2 Fibronectin type III domain ig PF00047.25 CBY35199.1 - 2.8e-12 46.6 0.0 7.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY35199.1 - 9.3e-12 45.1 0.0 4.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CBY35199.1 - 1.4e-07 31.6 0.0 0.022 15.0 0.0 3.9 2 2 0 2 2 2 2 Immunoglobulin V-set domain C1-set PF07654.15 CBY35199.1 - 0.036 14.4 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin C1-set domain C2-set_2 PF08205.12 CBY35199.1 - 0.095 12.8 0.1 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY35199.1 - 0.13 12.8 0.0 2.7 8.6 0.0 2.7 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Thyroglobulin_1 PF00086.18 CBY35201.1 - 1.4e-12 47.1 0.2 3.8e-12 45.7 0.2 1.7 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat DUF1221 PF06760.11 CBY35202.1 - 0.012 15.1 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) RPEL PF02755.15 CBY35202.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RPEL repeat Frizzled PF01534.17 CBY35203.1 - 4.7e-51 173.8 15.5 6.8e-51 173.2 15.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY35203.1 - 3e-13 50.4 2.7 6e-13 49.4 2.7 1.5 1 0 0 1 1 1 1 Fz domain Dicty_CAR PF05462.11 CBY35203.1 - 1.5 7.9 14.6 0.33 10.0 8.7 2.0 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor DnaJ PF00226.31 CBY35204.1 - 6.7e-25 87.0 2.2 6.7e-25 87.0 2.2 2.0 3 0 0 3 3 3 1 DnaJ domain Ank_4 PF13637.6 CBY35205.1 - 6.6e-17 61.6 0.0 2.5e-08 34.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SH3_9 PF14604.6 CBY35205.1 - 1.4e-15 56.8 0.8 3e-15 55.8 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain Ank_5 PF13857.6 CBY35205.1 - 3.2e-14 52.8 0.0 6e-07 29.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35205.1 - 2.1e-13 50.7 0.0 9.4e-13 48.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 CBY35205.1 - 5e-13 48.4 0.2 9.3e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY35205.1 - 2.1e-11 43.3 0.4 6.7e-11 41.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Ank_3 PF13606.6 CBY35205.1 - 8.9e-09 34.9 0.0 0.045 14.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CBY35205.1 - 7.5e-08 32.5 0.0 0.0048 17.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat PH_12 PF16457.5 CBY35207.1 - 3.6e-16 59.9 3.4 5.6e-16 59.3 0.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 CBY35207.1 - 1.5e-14 54.5 0.4 5.2e-14 52.8 0.1 2.1 2 0 0 2 2 2 1 ELMO/CED-12 family ALMS_motif PF15309.6 CBY35208.1 - 3.4e-34 118.2 16.7 3.4e-34 118.2 16.7 3.8 4 1 0 4 4 4 1 ALMS motif DUF2200 PF09966.9 CBY35208.1 - 0.036 14.2 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) Pup PF05639.11 CBY35208.1 - 0.2 12.6 7.1 0.65 11.0 0.6 4.3 2 0 0 2 2 2 0 Pup-like protein TMEM144 PF07857.12 CBY35209.1 - 6.8e-33 114.0 4.1 7.6e-33 113.9 4.1 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 CBY35209.1 - 1.6e-10 40.8 5.2 2.5e-10 40.2 5.2 1.3 1 1 0 1 1 1 1 Sugar transport protein EamA PF00892.20 CBY35209.1 - 0.008 16.3 12.5 0.013 15.7 12.5 1.4 1 1 0 1 1 1 1 EamA-like transporter family DUF2427 PF10348.9 CBY35209.1 - 0.027 14.2 0.5 0.027 14.2 0.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Multi_Drug_Res PF00893.19 CBY35209.1 - 0.17 12.6 6.8 0.15 12.8 2.9 2.2 1 1 1 2 2 2 0 Small Multidrug Resistance protein TPR_14 PF13428.6 CBY35210.1 - 8.2e-06 26.2 0.0 0.013 16.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY35210.1 - 0.0089 16.1 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY35210.1 - 0.027 13.7 0.0 0.066 12.4 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY35210.1 - 0.038 14.3 0.4 6.7 7.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 CBY35210.1 - 0.064 12.2 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBY35210.1 - 0.088 13.5 0.0 9.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TP_methylase PF00590.20 CBY35211.1 - 2.1e-06 27.8 0.0 2.1e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TP_methylase PF00590.20 CBY35212.1 - 2.8e-10 40.5 0.0 3.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Q_salvage PF10343.9 CBY35212.1 - 0.015 14.9 0.2 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family SpoVAD PF07451.11 CBY35212.1 - 0.046 12.4 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF3652 PF12372.8 CBY35214.1 - 0.054 13.4 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Huntingtin protein region Glyco_hydro_38C PF07748.13 CBY35215.1 - 8.2e-17 62.0 0.3 8.6e-17 61.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Sugar_tr PF00083.24 CBY35218.1 - 1.1e-22 80.6 21.0 1.4e-22 80.2 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35218.1 - 2.9e-19 69.2 25.2 3.5e-16 59.1 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COX1 PF00115.20 CBY35219.1 - 0.00016 20.7 2.7 0.00019 20.4 2.7 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I YtpI PF14007.6 CBY35219.1 - 0.01 16.0 6.7 0.056 13.6 3.3 2.4 2 0 0 2 2 2 0 YtpI-like protein YfhO PF09586.10 CBY35219.1 - 0.011 14.0 1.9 0.014 13.7 1.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO GWT1 PF06423.12 CBY35219.1 - 0.029 14.5 6.5 0.046 13.9 3.8 1.9 1 1 1 2 2 2 0 GWT1 AgrB PF04647.15 CBY35219.1 - 5.6 6.2 13.1 13 5.1 12.9 1.6 1 1 1 2 2 2 0 Accessory gene regulator B SH2 PF00017.24 CBY35220.1 - 0.00057 19.9 0.0 0.00082 19.4 0.0 1.2 1 0 0 1 1 1 1 SH2 domain EGF_2 PF07974.13 CBY35221.1 - 7e-13 48.7 96.8 0.00013 22.2 14.7 6.7 6 0 0 6 6 6 6 EGF-like domain EGF PF00008.27 CBY35221.1 - 0.00011 22.4 68.1 0.0036 17.6 5.1 6.7 6 0 0 6 6 6 3 EGF-like domain DUF3333 PF11812.8 CBY35221.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) RHS_repeat PF05593.14 CBY35221.1 - 0.041 14.4 1.7 5.8 7.5 0.0 4.6 6 0 0 6 6 6 0 RHS Repeat MORN_2 PF07661.13 CBY35221.1 - 0.047 13.9 0.5 14 6.3 0.0 4.6 5 0 0 5 5 5 0 MORN repeat variant SspH PF08141.12 CBY35221.1 - 0.31 11.2 1.4 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Small acid-soluble spore protein H family Sugar_tr PF00083.24 CBY35222.1 - 5.8e-16 58.4 9.1 9.5e-16 57.7 9.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35222.1 - 2.6e-07 29.9 23.0 5.9e-06 25.4 14.1 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY35223.1 - 1.4e-10 40.7 8.1 1.9e-10 40.2 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY35223.1 - 1.4e-07 30.7 15.5 3.5e-07 29.5 15.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LON_substr_bdg PF02190.16 CBY35224.1 - 0.27 11.1 2.8 0.7 9.7 2.8 1.7 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Sec7 PF01369.20 CBY35225.1 - 3.9e-59 199.4 0.3 1.4e-58 197.6 0.3 2.0 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 CBY35225.1 - 1.6e-49 167.4 0.1 4.1e-49 166.1 0.1 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 CBY35225.1 - 0.0033 17.9 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 PH domain IQ PF00612.27 CBY35225.1 - 6.8 6.8 8.5 0.51 10.3 1.4 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif RRM_1 PF00076.22 CBY35226.1 - 1.5e-16 59.9 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY35226.1 - 0.00011 21.8 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CBY35226.1 - 0.0028 17.8 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 RRM-like domain RRM_7 PF16367.5 CBY35226.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif zf-CHCC PF10276.9 CBY35227.1 - 3.9e-16 58.8 1.6 5.8e-16 58.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain RimK PF08443.11 CBY35227.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain COX5B PF01215.19 CBY35227.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb XLF PF09302.11 CBY35228.1 - 0.065 13.4 5.1 0.7 10.0 0.1 2.4 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Golgin_A5 PF09787.9 CBY35228.1 - 0.15 11.5 18.3 1 8.7 18.4 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 ALMT PF11744.8 CBY35228.1 - 0.16 10.8 6.6 0.2 10.4 6.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ABC_tran_CTD PF16326.5 CBY35228.1 - 0.16 12.2 15.8 0.24 11.7 0.8 3.3 2 1 0 3 3 3 0 ABC transporter C-terminal domain Paralemmin PF03285.15 CBY35228.1 - 0.18 11.4 9.0 0.27 10.8 8.1 1.7 1 1 1 2 2 2 0 Paralemmin FlxA PF14282.6 CBY35228.1 - 0.19 11.7 7.4 0.77 9.8 3.5 2.5 2 0 0 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 CBY35228.1 - 1.9 8.7 18.6 0.7 10.1 4.5 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 CBY35228.1 - 3.3 8.2 10.1 1.5 9.3 3.9 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ZapA PF05164.13 CBY35228.1 - 5.4 7.5 8.3 19 5.7 8.1 2.0 1 1 0 1 1 1 0 Cell division protein ZapA DUF5595 PF18077.1 CBY35228.1 - 7.6 6.7 8.6 5 7.3 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF3450 PF11932.8 CBY35228.1 - 8.9 5.5 15.0 1.6 8.0 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WDCP PF15390.6 CBY35228.1 - 9.5 4.5 10.2 7.9 4.7 8.9 1.3 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Snf7 PF03357.21 CBY35229.1 - 3.7e-17 62.4 17.9 4.5e-17 62.2 17.9 1.0 1 0 0 1 1 1 1 Snf7 GAGA_bind PF06217.12 CBY35229.1 - 0.082 13.2 6.6 0.1 12.8 6.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Methyltrn_RNA_4 PF09936.9 CBY35229.1 - 0.13 12.1 2.1 0.23 11.3 2.1 1.5 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Sulfotransfer_4 PF17784.1 CBY35229.1 - 0.29 10.9 1.7 0.33 10.7 0.1 1.8 2 0 0 2 2 2 0 Sulfotransferase domain hGDE_central PF14702.6 CBY35229.1 - 0.57 9.8 6.2 0.56 9.8 5.1 1.4 1 1 0 1 1 1 0 Central domain of human glycogen debranching enzyme CENP-Q PF13094.6 CBY35229.1 - 0.7 10.1 13.4 0.26 11.5 10.8 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GrpE PF01025.19 CBY35229.1 - 1.4 8.6 16.8 0.14 11.9 11.9 1.8 2 1 0 2 2 2 0 GrpE Med9 PF07544.13 CBY35229.1 - 1.4 9.0 6.4 7.3 6.8 0.4 3.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 CBY35229.1 - 1.6 7.6 7.0 2 7.2 7.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mt_ATP-synt_D PF05873.12 CBY35229.1 - 3.8 7.4 11.3 4.2 7.2 1.3 2.7 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Snf7 PF03357.21 CBY35230.1 - 1.3e-13 50.9 16.8 1.7e-13 50.6 16.8 1.1 1 0 0 1 1 1 1 Snf7 hGDE_central PF14702.6 CBY35230.1 - 0.03 14.0 2.4 0.048 13.3 2.4 1.3 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme YtzH PF14165.6 CBY35230.1 - 0.081 13.3 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 YtzH-like protein zf-met PF12874.7 CBY35233.1 - 2.4e-10 40.4 3.1 3.1e-05 24.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY35233.1 - 0.0078 16.5 3.9 0.85 10.0 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY35233.1 - 0.07 13.4 2.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 CBY35233.1 - 1.2 9.0 7.6 0.73 9.6 0.1 2.7 2 1 0 2 2 2 0 U1 zinc finger zf_C2H2_6 PF18450.1 CBY35233.1 - 5.3 6.9 5.9 36 4.2 2.0 2.5 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2 PF00096.26 CBY35233.1 - 6.2 7.5 6.4 35 5.1 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Trypsin PF00089.26 CBY35235.1 - 1.5e-28 100.1 0.0 1.8e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Trypsin Vault PF01505.18 CBY35236.1 - 1.9e-58 194.4 0.5 1.4e-16 60.3 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 CBY35236.1 - 5.7e-48 161.8 0.5 1.4e-47 160.6 0.5 1.7 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 CBY35236.1 - 2.5e-31 107.8 0.2 3.7e-21 75.3 0.2 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 CBY35236.1 - 3.7e-30 103.7 2.4 4.4e-27 93.9 0.1 3.4 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 CBY35236.1 - 5.1e-29 100.1 0.1 5.6e-28 96.8 0.2 2.7 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CBY35236.1 - 0.0023 18.0 0.0 1.4 9.0 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3601) ERM PF00769.19 CBY35236.1 - 0.79 9.5 24.5 1.5 8.6 24.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DEAD PF00270.29 CBY35237.1 - 1.5e-48 164.9 0.0 3.1e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY35237.1 - 4e-32 110.8 0.0 1.1e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY35237.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 CBY35237.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Cg6151-P PF10233.9 CBY35239.1 - 5.4e-16 58.9 5.7 6.6e-16 58.6 5.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2981 PF11200.8 CBY35239.1 - 0.043 13.6 0.6 0.063 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Peptidase_C1 PF00112.23 CBY35240.1 - 3.1e-78 262.8 5.3 4.6e-78 262.3 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY35240.1 - 1e-14 54.7 1.3 1.8e-14 53.9 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY35240.1 - 0.019 13.8 2.0 2.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Peptidase C1-like family TFIIA PF03153.13 CBY35241.1 - 5.9e-49 168.2 25.4 8.4e-34 118.3 24.9 2.5 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CBY35241.1 - 4 5.6 15.3 4.8 5.3 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEAT_EZ PF13513.6 CBY35242.1 - 1.8e-08 34.7 23.5 5.1e-05 23.7 0.2 8.9 11 2 1 12 12 12 3 HEAT-like repeat HEAT PF02985.22 CBY35242.1 - 1.9e-06 27.6 12.0 0.35 11.2 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 CBY35242.1 - 1.1e-05 25.8 3.5 0.065 13.6 0.1 6.5 5 3 2 7 7 7 1 HEAT repeats Cnd3 PF12719.7 CBY35242.1 - 0.00016 21.0 0.6 0.015 14.5 0.0 3.9 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain MIP PF00230.20 CBY35242.1 - 0.0053 16.5 0.9 0.094 12.4 0.0 2.4 2 0 0 2 2 2 1 Major intrinsic protein RTP1_C1 PF10363.9 CBY35242.1 - 0.027 14.6 0.0 9.5 6.4 0.0 4.6 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4704 PF15787.5 CBY35242.1 - 0.49 9.6 5.3 0.33 10.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) Importin_rep_4 PF18808.1 CBY35242.1 - 0.93 9.8 6.9 8 6.8 0.0 4.8 5 0 0 5 5 5 0 Importin repeat Xan_ur_permease PF00860.20 CBY35243.1 - 1.3e-55 188.7 3.8 1.3e-55 188.7 3.8 1.6 2 0 0 2 2 2 1 Permease family Patatin PF01734.22 CBY35244.1 - 8e-17 62.1 0.0 1.2e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_2 PF12796.7 CBY35244.1 - 1.3e-13 51.3 0.5 1.1e-08 35.5 0.1 3.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY35244.1 - 1.5e-13 50.9 0.1 1.9e-09 37.9 0.0 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY35244.1 - 1.9e-11 43.9 0.0 1.2e-06 28.6 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY35244.1 - 1.4e-10 41.1 0.2 3.7e-05 24.0 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CBY35244.1 - 9.5e-10 37.9 0.2 0.00013 22.1 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Y_phosphatase PF00102.27 CBY35245.1 - 5.9e-32 111.1 0.0 8.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.11 CBY35246.1 - 3.9e-51 174.1 12.8 4.6e-51 173.8 12.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY35246.1 - 5.9e-15 55.6 14.8 1.5e-07 31.6 6.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CBY35246.1 - 8e-11 41.8 11.0 9.5e-10 38.3 11.1 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CBY35246.1 - 0.00078 18.7 3.2 0.37 9.9 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TMEM234 PF10639.9 CBY35246.1 - 0.029 14.4 3.3 2.6 8.1 0.2 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 7tm_1 PF00001.21 CBY35246.1 - 2.7 7.2 9.7 0.36 10.1 3.9 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) 2OG-FeII_Oxy_3 PF13640.6 CBY35248.1 - 3.1e-10 40.8 0.0 6.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DKNYY PF13644.6 CBY35248.1 - 0.0016 19.2 4.1 0.052 14.3 0.2 1.8 1 1 1 2 2 2 2 DKNYY family ETRAMP PF09716.10 CBY35248.1 - 0.013 15.5 0.0 0.89 9.7 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Oxygenase-NA PF09859.9 CBY35248.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Phospholip_A2_1 PF00068.19 CBY35250.1 - 3.2e-18 66.2 8.9 3.2e-18 66.2 8.9 1.7 2 0 0 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.17 CBY35251.1 - 5e-31 107.9 0.0 7.8e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35251.1 - 4.7e-10 39.3 0.0 8.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAGBD PF16828.5 CBY35251.1 - 0.059 13.5 0.1 0.5 10.4 0.1 2.4 2 0 0 2 2 2 0 GAG-binding domain on surface antigen Gar1 PF04410.14 CBY35253.1 - 1.1e-35 122.7 0.0 1.4e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Senescence PF06911.12 CBY35254.1 - 3.9e-27 95.7 8.3 5.9e-27 95.2 8.3 1.2 1 0 0 1 1 1 1 Senescence-associated protein p450 PF00067.22 CBY35255.1 - 4.4e-71 240.0 0.0 6.6e-71 239.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MORN PF02493.20 CBY35257.1 - 7.3e-37 123.1 36.5 2.2e-06 27.2 1.4 7.5 7 0 0 7 7 7 7 MORN repeat Cbl_N3 PF02762.14 CBY35257.1 - 0.69 9.8 4.8 11 6.0 0.0 3.8 1 1 3 4 4 4 0 CBL proto-oncogene N-terminus, SH2-like domain MAM PF00629.23 CBY35258.1 - 5.3e-107 354.7 1.6 1.7e-25 89.8 0.0 8.1 6 3 0 7 7 7 6 MAM domain, meprin/A5/mu Astacin PF01400.24 CBY35258.1 - 1.6e-30 106.1 0.0 3.1e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) fn3 PF00041.21 CBY35258.1 - 1.6e-28 98.9 28.4 2e-05 24.9 0.2 13.8 12 3 0 13 13 13 6 Fibronectin type III domain CUB PF00431.20 CBY35258.1 - 2.2e-15 56.9 0.1 7.2e-15 55.3 0.1 2.0 1 0 0 1 1 1 1 CUB domain TSP_1 PF00090.19 CBY35258.1 - 1.9e-09 37.6 9.0 4.6e-09 36.4 9.0 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Pur_ac_phosph_N PF16656.5 CBY35258.1 - 0.0017 18.9 14.6 2 9.0 0.9 7.9 6 2 0 6 6 6 2 Purple acid Phosphatase, N-terminal domain DUF4992 PF16383.5 CBY35258.1 - 0.0093 15.5 0.7 0.0093 15.5 0.7 4.5 5 1 1 6 6 6 1 Domain of unknown function CBM_4_9 PF02018.17 CBY35258.1 - 0.066 13.5 6.3 12 6.1 0.1 5.7 4 1 1 5 5 5 0 Carbohydrate binding domain Peptidase_M14 PF00246.24 CBY35259.1 - 1.8e-08 34.5 1.8 6.4e-06 26.2 0.1 2.8 2 1 1 3 3 3 2 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CBY35259.1 - 0.00023 21.4 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Trypsin PF00089.26 CBY35260.1 - 4.2e-228 752.6 46.6 1.5e-55 188.4 0.4 9.2 7 2 0 7 7 7 6 Trypsin DUF1986 PF09342.11 CBY35260.1 - 0.056 13.8 3.8 10 6.5 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1986) Trypsin PF00089.26 CBY35261.1 - 5e-10 39.6 0.1 6.3e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY35261.1 - 0.0015 18.9 0.8 0.0057 17.0 0.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1986) La PF05383.17 CBY35262.1 - 1.5e-15 57.0 0.3 3.4e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY35262.1 - 0.015 15.1 0.9 4.7 7.1 0.9 2.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-1_beta_acid PF10587.9 CBY35262.1 - 0.032 14.7 1.0 0.09 13.2 1.0 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region POTRA_2 PF08479.11 CBY35263.1 - 0.026 14.4 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 POTRA domain, ShlB-type TPR_14 PF13428.6 CBY35265.1 - 0.16 12.9 0.8 0.72 10.8 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 CBY35266.1 - 2.2e-06 27.6 2.3 3.1e-06 27.1 2.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit PP1c_bdg PF10488.9 CBY35266.1 - 0.0045 16.5 0.3 0.0049 16.4 0.3 1.2 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region RmuC PF02646.16 CBY35266.1 - 0.019 14.1 5.0 0.15 11.1 0.8 2.0 2 0 0 2 2 2 0 RmuC family Prefoldin PF02996.17 CBY35266.1 - 0.032 14.1 8.1 0.19 11.6 8.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBY35266.1 - 0.23 11.5 9.8 0.79 9.8 2.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.25 CBY35266.1 - 0.27 10.9 6.6 3.8 7.1 0.8 2.1 2 0 0 2 2 2 0 Syntaxin DUF1664 PF07889.12 CBY35266.1 - 0.31 11.1 3.8 2.7 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CBY35266.1 - 0.39 11.2 5.9 7.6 7.0 1.5 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.10 CBY35266.1 - 0.42 10.9 3.3 7.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF2443 PF10398.9 CBY35266.1 - 0.52 10.4 3.5 0.81 9.8 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DivIC PF04977.15 CBY35266.1 - 1.1 9.0 6.3 4.2 7.2 3.7 2.1 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 CBY35266.1 - 1.3 9.5 8.4 0.99 9.8 1.2 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Glyco_hydro_15 PF00723.21 CBY35267.1 - 3.9e-96 322.5 0.0 5.3e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.25 CBY35269.1 - 2e-78 263.4 0.1 2.5e-78 263.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35269.1 - 4.1e-38 131.2 0.2 2.4e-37 128.6 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY35269.1 - 1.2e-08 34.3 0.4 2.2e-08 33.5 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY35269.1 - 0.00049 20.1 0.0 0.0089 16.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY35269.1 - 0.0025 16.9 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 CBY35269.1 - 0.038 13.6 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CBY35269.1 - 0.05 13.0 0.2 0.099 12.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trypsin PF00089.26 CBY35270.1 - 1.3e-55 188.7 0.6 1.7e-55 188.2 0.6 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY35270.1 - 2.8e-07 31.5 0.1 5.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain WD40 PF00400.32 CBY35271.1 - 1.5e-12 47.8 14.2 0.0045 17.8 0.0 10.1 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35271.1 - 5.1e-06 26.7 0.0 17 5.8 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain CENP-B_dimeris PF09026.10 CBY35271.1 - 0.62 10.5 7.7 2 8.8 7.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Anthrax_toxA PF03497.16 CBY35271.1 - 2.6 8.1 7.3 1.4 9.0 2.1 3.0 2 1 0 2 2 2 0 Anthrax toxin LF subunit MT PF12777.7 CBY35272.1 - 6e-149 495.7 8.7 2.9e-115 385.0 6.7 2.5 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CBY35272.1 - 4.5e-99 331.5 1.7 2.4e-70 237.1 0.0 2.7 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CBY35272.1 - 8.6e-99 330.1 0.0 2e-98 328.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 CBY35272.1 - 1.7e-76 257.9 0.9 7.1e-67 226.2 0.0 2.6 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBY35272.1 - 2.7e-75 252.3 0.4 9.1e-75 250.6 0.4 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY35272.1 - 6.4e-54 182.2 2.9 1e-48 165.3 0.0 3.8 3 1 1 4 4 4 2 P-loop containing dynein motor region AAA_lid_1 PF17857.1 CBY35272.1 - 2.8e-39 133.3 0.4 9.9e-39 131.6 0.4 2.0 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBY35272.1 - 2.4e-13 50.3 0.8 7.7e-07 29.3 0.1 3.1 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY35272.1 - 0.00037 20.5 0.0 0.3 11.1 0.0 3.9 3 1 0 4 4 4 1 AAA domain (dynein-related subfamily) Jnk-SapK_ap_N PF09744.9 CBY35272.1 - 1.6 8.9 11.6 0.85 9.8 3.3 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DHC_N1 PF08385.12 CBY35273.1 - 6.4e-135 450.9 8.2 4.1e-90 303.0 1.1 3.1 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBY35273.1 - 0.0051 16.0 0.8 0.0051 16.0 0.8 4.3 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 Spectrin PF00435.21 CBY35273.1 - 0.089 13.3 4.8 1.6 9.3 0.0 4.4 4 1 0 4 4 4 0 Spectrin repeat BAG6 PF12057.8 CBY35273.1 - 0.09 12.5 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 BCL2-associated athanogene 6 Retrotran_gag_2 PF14223.6 CBY35273.1 - 0.12 12.1 2.5 11 5.6 0.2 3.2 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF4363 PF14276.6 CBY35273.1 - 6.6 6.9 11.5 6 7.0 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4363) Acyl-CoA_dh_1 PF00441.24 CBY35274.1 - 2.7e-35 121.8 0.1 4.7e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY35274.1 - 6.6e-28 96.8 0.0 1.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY35274.1 - 1.5e-22 80.4 0.0 5.5e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY35274.1 - 1.2e-12 48.3 0.0 3.2e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBY35274.1 - 0.0036 17.0 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Galactosyl_T PF01762.21 CBY35275.1 - 6.5e-29 101.1 0.0 1.6e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase Lamp PF01299.17 CBY35276.1 - 4e-10 39.7 4.2 1.1e-08 35.0 2.6 3.8 3 1 0 3 3 3 2 Lysosome-associated membrane glycoprotein (Lamp) Macoilin PF09726.9 CBY35276.1 - 2.7 6.4 17.1 3.8 5.9 17.1 1.2 1 0 0 1 1 1 0 Macoilin family Ion_trans PF00520.31 CBY35277.1 - 3.4e-238 786.2 92.9 3.5e-68 229.5 10.7 4.1 4 0 0 4 4 4 4 Ion transport protein Ca_chan_IQ PF08763.11 CBY35277.1 - 3.3e-31 107.3 0.1 8.6e-31 106.0 0.1 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain GPHH PF16905.5 CBY35277.1 - 1.5e-26 91.9 0.1 6.5e-26 89.9 0.1 2.2 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 CBY35277.1 - 2.3e-08 33.2 88.5 8.8e-06 24.6 10.8 9.5 7 3 3 10 10 10 7 Polycystin cation channel CAC1F_C PF16885.5 CBY35277.1 - 1.4e-05 24.9 6.8 0.032 13.9 0.1 2.9 3 0 0 3 3 3 2 Voltage-gated calcium channel subunit alpha, C-term DUF4773 PF15998.5 CBY35277.1 - 0.05 14.1 1.2 2.4 8.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4773) PAX PF00292.18 CBY35278.1 - 2.4e-62 208.4 0.2 2.4e-62 208.4 0.2 1.5 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.6 CBY35278.1 - 7.6e-05 22.4 0.4 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 CBY35278.1 - 0.013 15.6 0.2 0.031 14.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 CBY35278.1 - 0.041 13.6 2.5 0.081 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 CBY35278.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 CBY35278.1 - 0.096 12.6 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 MarR family ATP-gua_Ptrans PF00217.19 CBY35279.1 - 1.7e-57 194.4 0.0 2.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY35279.1 - 4.1e-23 81.5 0.0 7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain KH_1 PF00013.29 CBY35281.1 - 1.1e-66 220.5 17.4 1.3e-17 63.3 0.4 4.3 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 CBY35281.1 - 1.5e-20 72.7 5.1 0.00014 21.6 0.0 4.4 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY35281.1 - 1.1e-10 41.2 6.5 0.0064 16.3 0.2 4.4 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CBY35281.1 - 1.3e-08 34.8 6.3 0.16 12.1 0.0 4.3 4 0 0 4 4 4 3 NusA-like KH domain SLS PF14611.6 CBY35281.1 - 0.00012 22.0 0.2 0.1 12.4 0.1 3.4 2 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator MOEP19 PF16005.5 CBY35281.1 - 0.0052 16.8 0.1 6.4 6.9 0.0 3.5 4 0 0 4 4 4 1 KH-like RNA-binding domain Gar1 PF04410.14 CBY35282.1 - 2.5e-29 102.1 0.3 6.3e-29 100.7 0.3 1.7 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RRM_1 PF00076.22 CBY35282.1 - 0.00018 21.3 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dsrm PF00035.26 CBY35283.1 - 8.9e-12 45.5 0.3 6.7e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY35283.1 - 5.3e-06 26.5 0.1 2.9 8.1 0.0 3.5 3 0 0 3 3 3 3 Dicer dimerisation domain DZF PF07528.14 CBY35283.1 - 0.043 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 DZF domain dsRBD2 PF17842.1 CBY35283.1 - 0.28 11.4 1.8 31 4.8 0.0 3.1 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 Rrn6 PF10214.9 CBY35283.1 - 5.1 5.5 9.5 8.2 4.8 9.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Tropomyosin PF00261.20 CBY35284.1 - 0.00024 20.6 39.8 0.00088 18.7 39.8 1.8 1 1 0 1 1 1 1 Tropomyosin Ribosomal_L18p PF00861.22 CBY35284.1 - 0.0054 17.1 0.4 0.015 15.7 0.4 1.8 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast XhlA PF10779.9 CBY35284.1 - 9.7 6.5 15.0 1.6 9.0 0.9 3.9 3 1 0 3 3 3 0 Haemolysin XhlA Trypsin PF00089.26 CBY35285.1 - 3.9e-44 151.1 0.9 3.9e-44 151.1 0.9 2.3 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY35285.1 - 1.7e-31 108.8 2.4 6.9e-15 55.3 0.2 3.3 3 0 0 3 3 3 2 CUB domain LTD PF00932.19 CBY35285.1 - 0.0028 18.0 2.9 0.71 10.2 0.9 3.3 3 0 0 3 3 3 2 Lamin Tail Domain DUF1986 PF09342.11 CBY35285.1 - 0.016 15.6 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) FXa_inhibition PF14670.6 CBY35285.1 - 0.021 15.1 15.3 0.13 12.6 15.3 2.6 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site YHYH PF14240.6 CBY35287.1 - 6.3e-12 45.8 15.2 6.6e-12 45.8 0.0 3.3 2 1 1 3 3 3 2 YHYH protein RIFIN PF02009.16 CBY35287.1 - 3.9 7.3 13.8 5.7 6.7 13.8 1.1 1 0 0 1 1 1 0 Rifin Ank_2 PF12796.7 CBY35288.1 - 2.2e-31 108.3 0.0 3.3e-14 53.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY35288.1 - 3.7e-27 94.3 0.8 8.2e-11 42.2 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 CBY35288.1 - 1.2e-25 90.2 14.4 1.2e-25 90.2 14.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 CBY35288.1 - 4.6e-25 87.3 1.4 9.4e-08 32.2 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY35288.1 - 8.9e-25 86.0 0.1 0.00011 22.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY35288.1 - 4.3e-21 72.7 0.2 0.00078 19.7 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat MARVEL PF01284.23 CBY35288.1 - 0.0038 17.2 2.6 0.099 12.7 0.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain 7TM_GPCR_Srd PF10317.9 CBY35288.1 - 0.51 9.5 8.0 0.088 12.0 3.8 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd PID PF00640.23 CBY35289.1 - 8.8e-05 22.6 0.1 0.00023 21.2 0.1 1.8 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Gly-zipper_OmpA PF13436.6 CBY35289.1 - 1.8 8.4 6.3 5.9 6.8 6.3 1.9 1 0 0 1 1 1 0 Glycine-zipper domain tRNA-synt_1 PF00133.22 CBY35290.1 - 4.2e-229 761.8 0.3 5.5e-229 761.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBY35290.1 - 6.2e-29 100.9 0.1 1.2e-28 100.0 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBY35290.1 - 1.4e-17 63.5 3.6 1.6e-05 23.8 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CBY35290.1 - 0.016 14.6 0.0 0.1 12.0 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Chromo PF00385.24 CBY35291.1 - 7.6e-15 54.6 5.0 1.7e-14 53.5 5.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Acyl-CoA_dh_M PF02770.19 CBY35292.1 - 2.1e-15 56.7 0.0 3.5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 CBY35292.1 - 5.3e-11 42.4 0.1 8.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 CBY35292.1 - 8.6e-07 29.3 1.6 2.1e-06 28.0 0.5 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DnaJ PF00226.31 CBY35295.1 - 5e-13 49.0 0.3 5e-13 49.0 0.3 1.6 2 0 0 2 2 2 1 DnaJ domain Annexin PF00191.20 CBY35296.1 - 2.2e-71 235.8 9.3 6e-23 80.7 0.1 4.1 4 0 0 4 4 4 4 Annexin EcoEI_R_C PF08463.10 CBY35296.1 - 0.023 14.8 0.1 0.056 13.6 0.1 1.8 1 1 0 1 1 1 0 EcoEI R protein C-terminal Guanylate_cyc PF00211.20 CBY35297.1 - 1.9e-30 105.8 0.0 2.7e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY35298.1 - 2.3e-17 63.2 0.0 4.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35298.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY35298.1 - 0.0055 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ANF_receptor PF01094.28 CBY35298.1 - 0.13 11.4 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region Kelch_5 PF13854.6 CBY35299.1 - 2.3e-05 24.2 7.5 0.0064 16.5 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY35299.1 - 0.0093 15.5 11.5 4.9 6.8 0.8 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CBY35299.1 - 0.087 13.1 8.5 10 6.6 0.0 4.7 4 1 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY35299.1 - 0.25 11.4 10.1 1.7 8.7 0.1 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 CBY35299.1 - 3.5 7.7 8.1 65 3.6 0.0 4.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Sulfotransfer_2 PF03567.14 CBY35300.1 - 1.5e-06 28.3 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Kelch_6 PF13964.6 CBY35301.1 - 7e-07 29.3 0.2 0.025 14.9 0.0 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY35301.1 - 0.00024 21.0 0.2 0.01 15.8 0.1 3.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CBY35301.1 - 0.00049 20.3 0.5 0.025 14.8 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY35301.1 - 0.0018 18.2 2.0 12 6.0 0.0 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY35301.1 - 0.039 13.9 2.8 0.28 11.2 0.0 3.8 5 1 0 5 5 5 0 Kelch motif Kelch_1 PF01344.25 CBY35301.1 - 0.053 13.1 0.2 5.6 6.6 0.1 3.3 2 0 0 2 2 2 0 Kelch motif zf-C2H2 PF00096.26 CBY35302.1 - 6.5e-20 70.4 34.3 2.5e-06 27.6 0.1 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35302.1 - 6.8e-14 51.4 30.5 0.0011 19.6 0.1 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY35302.1 - 1.3e-08 34.9 32.3 0.0005 20.4 0.1 7.3 7 1 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY35302.1 - 9e-06 25.8 18.8 0.0078 16.5 0.1 4.9 5 1 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY35302.1 - 1.8e-05 24.9 13.7 0.063 13.7 0.1 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY35302.1 - 3.3e-05 24.1 15.8 0.024 14.9 0.6 4.5 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CBY35302.1 - 0.00029 20.9 13.7 1.5 9.0 1.7 5.0 3 1 2 5 5 5 2 Zinc ribbon domain zf_UBZ PF18439.1 CBY35302.1 - 0.00067 19.2 14.8 0.18 11.4 0.8 5.2 5 0 0 5 5 5 1 Ubiquitin-Binding Zinc Finger GAGA PF09237.11 CBY35302.1 - 0.0067 16.2 9.1 7.6 6.4 0.0 4.7 5 0 0 5 5 4 0 GAGA factor Rubredoxin PF00301.20 CBY35302.1 - 0.0083 16.1 11.3 1.4 9.0 0.1 5.0 6 0 0 6 6 5 2 Rubredoxin Acetone_carb_G PF08882.11 CBY35302.1 - 0.026 14.7 4.7 0.22 11.7 0.0 3.7 3 1 1 4 4 3 0 Acetone carboxylase gamma subunit zf-C2H2_3 PF13878.6 CBY35302.1 - 0.077 12.8 0.1 0.077 12.8 0.1 4.7 4 2 1 5 5 4 0 zinc-finger of acetyl-transferase ESCO zinc_ribbon_9 PF14369.6 CBY35302.1 - 0.088 13.1 11.1 23 5.4 0.1 4.8 5 0 0 5 5 4 0 zinc-ribbon YhfH PF14149.6 CBY35302.1 - 0.11 12.5 0.1 0.11 12.5 0.1 4.4 5 0 0 5 5 4 0 YhfH-like protein Zf_RING PF16744.5 CBY35302.1 - 0.11 12.6 9.6 8.3 6.6 0.0 4.7 3 1 2 5 5 4 0 KIAA1045 RING finger FYVE PF01363.21 CBY35302.1 - 0.13 12.4 18.8 2.2 8.5 0.9 4.6 3 1 1 4 4 4 0 FYVE zinc finger Vac7 PF12751.7 CBY35302.1 - 0.24 10.8 13.7 1.3 8.4 6.0 2.1 1 1 1 2 2 2 0 Vacuolar segregation subunit 7 TF_Zn_Ribbon PF08271.12 CBY35302.1 - 0.3 10.7 10.6 23 4.6 0.0 4.6 4 1 0 4 4 4 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CBY35302.1 - 0.33 10.4 16.5 6.6 6.3 0.5 5.3 5 0 0 5 5 5 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 CBY35302.1 - 0.42 10.7 6.3 24 5.1 0.0 3.6 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain YacG PF03884.14 CBY35302.1 - 0.57 10.0 6.8 5.7 6.8 0.1 3.8 4 0 0 4 4 3 0 DNA gyrase inhibitor YacG zf-C2H2_6 PF13912.6 CBY35302.1 - 0.8 9.8 18.9 1.4 9.0 1.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY35302.1 - 1.4 9.6 12.8 5.4 7.7 1.2 4.1 2 1 3 5 5 4 0 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CBY35302.1 - 1.7 8.7 13.8 1.8 8.6 0.6 4.7 4 2 0 4 4 4 0 CpXC protein Zn-C2H2_12 PF18112.1 CBY35302.1 - 2.3 8.8 20.0 1.3 9.5 0.1 5.8 6 0 0 6 6 5 0 Autophagy receptor zinc finger-C2H2 domain Sgf11 PF08209.11 CBY35302.1 - 2.6 7.7 14.4 13 5.4 0.1 4.9 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) DUF2256 PF10013.9 CBY35302.1 - 2.7 8.2 13.3 10 6.4 0.3 5.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 CBY35302.1 - 2.8 8.0 18.6 0.076 13.0 1.1 4.2 5 0 0 5 5 4 0 Transposase zinc-ribbon domain zf-BED PF02892.15 CBY35302.1 - 3 8.0 16.6 2.4 8.3 0.3 4.6 2 1 2 4 4 4 0 BED zinc finger CxC7 PF18866.1 CBY35302.1 - 4.3 7.6 7.7 29 4.9 0.1 4.1 3 1 1 4 4 4 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2HC_2 PF13913.6 CBY35302.1 - 5.2 7.1 18.9 2.1 8.3 0.0 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DZR PF12773.7 CBY35302.1 - 5.8 7.0 16.7 8.5 6.5 3.9 4.1 2 2 0 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.6 CBY35302.1 - 7.4 6.8 19.4 7.2 6.8 0.8 5.2 2 2 2 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Prok-RING_1 PF14446.6 CBY35302.1 - 8.1 6.5 16.6 7.4 6.6 0.3 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 CBY35302.1 - 9.1 7.1 20.6 5.3 7.9 2.3 4.8 3 2 1 4 4 4 0 zinc-ribbon family zf-C4_Topoisom PF01396.19 CBY35302.1 - 9.5 6.1 9.2 20 5.0 0.2 3.9 4 0 0 4 4 3 0 Topoisomerase DNA binding C4 zinc finger LPD5 PF18799.1 CBY35303.1 - 0.0076 16.7 0.1 0.0076 16.7 0.1 1.1 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 Rhodanese PF00581.20 CBY35304.1 - 2.7e-12 47.1 0.0 4.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain NEMP PF10225.9 CBY35306.1 - 3.1e-31 109.0 21.2 4.2e-29 102.0 21.2 2.3 1 1 0 1 1 1 1 NEMP family DcuA_DcuB PF03605.14 CBY35306.1 - 0.056 12.3 3.9 0.15 10.9 3.9 1.7 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4133 PF13571.6 CBY35306.1 - 0.33 11.3 0.0 0.33 11.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) NEMP PF10225.9 CBY35307.1 - 3.3e-05 23.7 0.5 4.3e-05 23.3 0.1 1.4 2 0 0 2 2 2 1 NEMP family DUF2570 PF10828.8 CBY35307.1 - 0.0023 17.7 0.2 0.0023 17.7 0.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2570) DUF5507 PF17612.2 CBY35307.1 - 0.041 13.6 0.4 0.051 13.3 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5507) Glycos_transf_1 PF00534.20 CBY35308.1 - 3.6e-11 42.9 0.0 8.3e-11 41.7 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY35308.1 - 8.5e-10 39.2 0.0 2.9e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBY35308.1 - 1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY35308.1 - 0.00061 19.8 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CBY35308.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain ATP-synt_E_2 PF08112.11 CBY35308.1 - 0.12 12.6 0.7 0.47 10.8 0.1 2.2 2 0 0 2 2 2 0 ATP synthase epsilon subunit Redoxin PF08534.10 CBY35308.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Redoxin UNC-50 PF05216.13 CBY35309.1 - 3.7e-77 258.8 20.9 4.3e-77 258.6 20.9 1.0 1 0 0 1 1 1 1 UNC-50 family Porin_6 PF16939.5 CBY35309.1 - 0.037 13.1 2.7 2.2 7.3 0.3 2.1 2 0 0 2 2 2 0 Putative porin PRRSV_2b PF07069.11 CBY35309.1 - 0.57 10.7 0.2 0.57 10.7 0.2 3.1 3 1 1 4 4 4 0 Porcine reproductive and respiratory syndrome virus 2b TCTP PF00838.17 CBY35310.1 - 1.5e-59 201.0 0.0 1.7e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RIBIOP_C PF04950.12 CBY35312.1 - 4.4e-105 351.3 0.1 8.4e-105 350.4 0.1 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBY35312.1 - 2.6e-05 24.2 0.1 0.0002 21.4 0.1 2.4 1 1 0 1 1 1 1 AARP2CN (NUC121) domain Pes-10 PF07149.11 CBY35312.1 - 3 6.8 10.0 4.2 6.3 10.0 1.2 1 0 0 1 1 1 0 Pes-10 CH_2 PF06294.11 CBY35313.1 - 2.7e-29 101.1 0.1 6.3e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY35313.1 - 3.6e-14 52.3 0.0 6.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 CBY35313.1 - 0.0075 16.4 0.6 0.027 14.6 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain TPD52 PF04201.15 CBY35313.1 - 0.12 11.9 3.8 0.3 10.7 3.8 1.6 1 0 0 1 1 1 0 Tumour protein D52 family PKcGMP_CC PF16808.5 CBY35313.1 - 0.13 12.2 4.4 0.36 10.7 4.4 1.9 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CH_2 PF06294.11 CBY35314.1 - 3.9e-11 42.9 0.2 1e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBY35314.1 - 8e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain WD40 PF00400.32 CBY35315.1 - 8.7e-32 108.7 12.3 3.9e-08 33.8 0.0 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35315.1 - 2.6e-16 59.7 2.7 6.1e-06 26.4 0.3 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY35315.1 - 9.5e-10 38.7 0.1 0.0024 17.8 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 CBY35315.1 - 0.037 12.0 1.0 0.1 10.6 1.0 1.6 1 1 0 1 1 1 0 IKI3 family PRP21_like_P PF12230.8 CBY35316.1 - 3.1e-43 148.2 9.2 6.2e-43 147.2 9.2 1.5 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CBY35316.1 - 2.9e-39 132.8 6.1 1.1e-19 70.2 0.5 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 CBY35316.1 - 1.8e-11 43.6 0.0 4.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBY35316.1 - 0.00036 20.9 0.1 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Toprim_Crpt PF13342.6 CBY35316.1 - 0.068 13.2 0.4 15 5.6 0.1 2.5 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase HEAT PF02985.22 CBY35318.1 - 0.0014 18.8 0.1 0.043 14.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Arm_2 PF04826.13 CBY35318.1 - 0.0035 16.8 2.2 0.006 16.1 1.8 1.8 1 1 0 1 1 1 1 Armadillo-like DUF383 PF04063.14 CBY35318.1 - 0.033 13.9 0.5 0.065 12.9 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF383) NopRA1 PF16201.5 CBY35318.1 - 0.068 12.7 3.1 5.8 6.4 0.1 2.6 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Sel1 PF08238.12 CBY35319.1 - 0.019 15.6 0.0 0.092 13.5 0.0 2.1 2 0 0 2 2 2 0 Sel1 repeat Hepar_II_III_N PF16889.5 CBY35320.1 - 0.02 14.2 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Heparinase II/III N-terminus SHNi-TPR PF10516.9 CBY35320.1 - 0.082 12.4 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 SHNi-TPR LRR_8 PF13855.6 CBY35322.1 - 1.6e-36 123.9 37.1 5.2e-12 45.3 6.2 5.5 2 1 4 6 6 6 5 Leucine rich repeat LRR_5 PF13306.6 CBY35322.1 - 2.6e-19 69.5 13.4 9.6e-11 41.7 0.1 2.6 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 CBY35322.1 - 5.3e-11 43.0 0.2 1.1e-10 41.9 0.2 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_4 PF12799.7 CBY35322.1 - 4e-10 39.8 23.9 0.0011 19.4 4.2 5.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY35322.1 - 1.2e-07 31.5 9.1 0.00052 19.6 7.1 3.5 1 1 2 3 3 3 2 Leucine-rich repeat I-set PF07679.16 CBY35322.1 - 3.2e-07 30.3 0.2 1.4e-06 28.3 0.2 2.1 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY35322.1 - 7.4e-06 26.2 0.1 1.7e-05 25.0 0.0 1.6 2 0 0 2 2 1 1 Immunoglobulin domain ig PF00047.25 CBY35322.1 - 1.6e-05 25.0 0.1 3.4e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_4 PF16680.5 CBY35322.1 - 0.0029 17.8 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 CBY35322.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin V-set domain LRR_1 PF00560.33 CBY35322.1 - 0.46 11.2 17.4 7.8 7.5 0.1 6.3 4 1 1 5 5 5 0 Leucine Rich Repeat zf-C2H2_4 PF13894.6 CBY35326.1 - 9.4e-07 29.2 2.0 0.0016 19.1 0.2 4.9 3 3 1 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY35326.1 - 0.0036 17.7 1.0 0.0036 17.7 1.0 4.6 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY35326.1 - 0.092 13.1 17.0 0.84 10.0 9.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 CBY35326.1 - 0.25 11.1 10.1 0.15 11.9 1.1 2.5 2 0 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.6 CBY35326.1 - 9.2 6.4 17.1 2.6 8.1 0.1 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY35327.1 - 3.2e-08 33.8 2.3 0.00074 19.8 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2 PF00096.26 CBY35327.1 - 0.00036 20.8 20.5 0.098 13.2 0.3 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35327.1 - 0.00061 20.4 24.5 0.34 11.8 0.3 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY35327.1 - 0.0086 16.0 1.4 0.0086 16.0 1.4 4.4 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 CBY35327.1 - 0.016 15.5 14.6 0.75 10.2 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 CBY35327.1 - 0.12 12.6 5.2 0.64 10.2 4.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-MYST PF17772.1 CBY35327.1 - 0.19 11.4 16.0 1.4 8.6 2.5 4.1 4 1 0 4 4 4 0 MYST family zinc finger domain AhpC-TSA PF00578.21 CBY35328.1 - 1.5e-26 92.8 0.0 2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBY35328.1 - 2.8e-13 49.5 0.0 5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBY35328.1 - 3.3e-07 30.1 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin DRMBL PF07522.14 CBY35329.1 - 0.048 13.8 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase PXPV PF12778.7 CBY35331.1 - 1 9.3 5.7 1.8 8.5 5.7 1.3 1 0 0 1 1 1 0 PXPV repeat (3 copies) KH_8 PF17903.1 CBY35332.1 - 1.9e-30 104.8 0.1 1.9e-30 104.8 0.1 3.0 3 0 0 3 3 3 1 Krr1 KH1 domain KH_1 PF00013.29 CBY35332.1 - 0.00045 20.0 0.1 0.0013 18.5 0.1 1.8 1 0 0 1 1 1 1 KH domain BBS2_C PF14782.6 CBY35333.1 - 1.8e-104 349.9 1.2 1.8e-104 349.9 1.2 1.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CBY35333.1 - 7e-34 116.1 0.1 2.2e-32 111.3 0.1 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 CBY35333.1 - 4.5e-25 87.6 0.1 1.9e-23 82.4 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal ANAPC4_WD40 PF12894.7 CBY35333.1 - 0.0037 17.5 0.1 0.36 11.1 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 CBY35333.1 - 0.0079 15.8 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 CNH domain ubiquitin PF00240.23 CBY35335.1 - 8.4e-09 35.1 1.4 1.6e-08 34.1 1.3 1.6 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CBY35335.1 - 2.6e-05 24.3 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBY35335.1 - 0.0079 16.7 0.2 0.012 16.2 0.1 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Phtf-FEM1B_bdg PF12129.8 CBY35336.1 - 2e-33 115.4 0.1 2.8e-33 114.9 0.1 1.1 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Tmemb_185A PF10269.9 CBY35336.1 - 0.0048 16.6 0.5 0.0066 16.2 0.5 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Saf_2TM PF18303.1 CBY35336.1 - 0.081 12.5 0.6 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Phage_holin_8 PF16931.5 CBY35337.1 - 0.039 13.9 0.4 0.77 9.8 0.1 2.5 2 0 0 2 2 2 0 Putative phage holin GATase PF00117.28 CBY35339.1 - 5.4e-36 124.2 0.0 8.9e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBY35339.1 - 1.2e-12 48.1 0.0 3.8e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GMP_synt_C PF00958.22 CBY35339.1 - 9.1e-10 38.5 0.1 0.0011 18.9 0.0 3.4 4 0 0 4 4 4 2 GMP synthase C terminal domain NAD_synthase PF02540.17 CBY35339.1 - 5.9e-09 35.4 0.0 2.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 CBY35339.1 - 0.014 14.9 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 CBY35339.1 - 0.017 14.7 0.2 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 CBY35339.1 - 0.03 13.1 0.1 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.19 CBY35339.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Neur_chan_LBD PF02931.23 CBY35340.1 - 6.8e-25 87.8 0.5 1.2e-24 87.0 0.5 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY35340.1 - 0.00044 20.4 1.0 0.00067 19.8 1.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Phospholip_A2_1 PF00068.19 CBY35341.1 - 2.7e-11 43.9 10.2 2.7e-11 43.9 10.2 2.1 2 0 0 2 2 2 1 Phospholipase A2 bZIP_1 PF00170.21 CBY35342.1 - 5e-09 36.1 9.4 1e-08 35.1 9.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY35342.1 - 1.2e-08 34.9 8.8 3e-08 33.6 8.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY35342.1 - 0.00072 20.0 8.7 0.00072 20.0 8.7 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Aft1_OSA PF11785.8 CBY35343.1 - 0.062 13.7 2.2 0.062 13.7 2.2 1.9 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain Gal_Lectin PF02140.18 CBY35345.1 - 2.6e-15 56.6 0.1 7.5e-15 55.1 0.1 1.9 1 0 0 1 1 1 1 Galactose binding lectin domain Pkinase_Tyr PF07714.17 CBY35346.1 - 6e-37 127.3 0.0 8.5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35346.1 - 6.4e-19 68.3 0.0 9.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 CBY35346.1 - 5e-15 55.6 0.0 2.1e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_lbd PF01404.19 CBY35346.1 - 1.1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Ephrin_rec_like PF07699.13 CBY35346.1 - 0.002 17.9 6.8 0.002 17.9 6.8 2.8 2 1 1 3 3 3 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 CBY35346.1 - 0.009 16.6 0.0 8 7.1 0.0 2.6 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Sdh_cyt PF01127.22 CBY35346.1 - 0.074 13.1 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sacchrp_dh_NADP PF03435.18 CBY35347.1 - 2.9e-20 72.8 0.1 4.8e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBY35347.1 - 3.9e-07 30.1 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY35347.1 - 0.00021 20.4 0.0 0.00048 19.2 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CBY35347.1 - 0.00036 20.6 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CBY35347.1 - 0.0054 17.2 0.0 0.009 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY35347.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CBY35347.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.22 CBY35347.1 - 0.024 15.4 0.0 0.044 14.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PCI PF01399.27 CBY35348.1 - 6.2e-11 42.7 0.1 1.1e-08 35.5 0.0 3.5 4 1 0 4 4 4 1 PCI domain eIF3m_C_helix PF18005.1 CBY35348.1 - 4.9e-09 35.7 1.0 4.9e-09 35.7 1.0 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix SWI-SNF_Ssr4 PF08549.10 CBY35348.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SART-1 PF03343.13 CBY35349.1 - 0.00023 19.9 21.2 0.00032 19.4 21.2 1.1 1 0 0 1 1 1 1 SART-1 family Spore_coat_CotO PF14153.6 CBY35349.1 - 6.4 6.7 21.1 0.71 9.8 16.3 1.9 2 0 0 2 2 2 0 Spore coat protein CotO RGS PF00615.19 CBY35350.1 - 9.5e-24 83.9 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain RBD PF02196.15 CBY35350.1 - 4e-12 46.0 0.0 6.4e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain HEAT_2 PF13646.6 CBY35351.1 - 0.001 19.4 1.3 0.019 15.4 0.6 3.0 3 0 0 3 3 3 1 HEAT repeats V-ATPase_H_N PF03224.14 CBY35351.1 - 0.0021 17.4 0.7 0.94 8.7 0.1 2.8 2 1 0 2 2 2 2 V-ATPase subunit H AA_permease_2 PF13520.6 CBY35352.1 - 5.3e-40 137.5 25.2 6.5e-40 137.3 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY35352.1 - 2.5e-22 79.1 21.2 3.5e-22 78.6 21.2 1.2 1 0 0 1 1 1 1 Amino acid permease 7tm_2 PF00002.24 CBY35353.1 - 1.2e-11 44.4 0.8 1.7e-11 43.9 0.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Chordopox_A13L PF05961.11 CBY35353.1 - 0.0022 18.2 0.6 0.0022 18.2 0.6 3.0 3 0 0 3 3 3 1 Chordopoxvirus A13L protein DUF2794 PF10984.8 CBY35353.1 - 0.031 14.4 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) 7tm_7 PF08395.12 CBY35353.1 - 0.039 13.1 2.4 0.26 10.4 0.0 2.1 1 1 1 2 2 2 0 7tm Chemosensory receptor YcbB PF08664.10 CBY35353.1 - 0.12 12.4 0.2 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 YcbB domain LapA_dom PF06305.11 CBY35353.1 - 0.12 12.2 0.3 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 CBY35353.1 - 5.5 6.8 14.3 0.044 13.5 1.6 3.2 3 1 1 4 4 4 0 Vpu protein GMC_oxred_N PF00732.19 CBY35354.1 - 1.5e-84 283.9 0.0 1.9e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CBY35354.1 - 8.7e-39 133.3 0.0 1.4e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HRM PF02793.22 CBY35354.1 - 5.8e-05 23.3 0.9 0.00012 22.3 0.9 1.5 1 0 0 1 1 1 1 Hormone receptor domain Lycopene_cycl PF05834.12 CBY35354.1 - 7.7e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein 7tm_2 PF00002.24 CBY35354.1 - 0.00027 20.3 2.8 0.00042 19.7 2.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DAO PF01266.24 CBY35354.1 - 0.00085 19.0 0.1 0.0039 16.8 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase SUR7 PF06687.12 CBY35354.1 - 0.0017 18.0 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 SUR7/PalI family Pyr_redox_3 PF13738.6 CBY35354.1 - 0.0071 15.6 0.0 0.67 9.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY35354.1 - 0.017 14.2 0.0 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 CBY35354.1 - 0.019 14.2 0.0 0.46 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Claudin_3 PF06653.11 CBY35354.1 - 0.02 14.8 1.9 0.033 14.1 1.9 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NAD_binding_8 PF13450.6 CBY35354.1 - 0.031 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBY35354.1 - 0.12 11.0 0.0 0.91 8.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Connexin PF00029.19 CBY35355.1 - 4.2e-83 278.7 3.9 5.8e-83 278.2 3.9 1.2 1 0 0 1 1 1 1 Connexin DUF2207 PF09972.9 CBY35355.1 - 0.021 13.6 3.5 1.2 7.8 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4834 PF16118.5 CBY35355.1 - 0.2 12.6 2.4 4.3 8.4 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) ANAPC4_WD40 PF12894.7 CBY35356.1 - 3.3e-23 81.8 1.6 9.6e-06 25.8 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY35356.1 - 2e-21 75.9 12.3 0.00018 22.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CBY35356.1 - 6.5e-06 24.9 0.4 0.0021 16.7 0.4 2.5 1 1 2 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CBY35356.1 - 0.0002 20.5 0.0 0.093 11.8 0.0 2.6 1 1 1 3 3 3 2 Coatomer WD associated region Nup160 PF11715.8 CBY35356.1 - 0.00094 17.9 0.2 0.0049 15.6 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 IKI3 PF04762.12 CBY35356.1 - 0.00099 17.2 0.1 0.25 9.3 0.0 2.8 2 1 0 2 2 2 2 IKI3 family Peptidase_S9_N PF02897.15 CBY35356.1 - 0.0013 17.6 1.5 2.3 6.9 0.0 3.5 2 1 1 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Me-amine-dh_H PF06433.11 CBY35356.1 - 0.029 13.3 0.0 0.58 9.0 0.0 2.8 2 1 1 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 CBY35356.1 - 0.18 11.8 0.0 47 4.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NDUF_C2 PF06374.11 CBY35357.1 - 0.051 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) PRKCSH PF07915.13 CBY35358.1 - 1.6e-29 102.7 11.2 2.8e-14 53.9 5.7 3.1 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CBY35358.1 - 5.4e-10 39.2 0.5 0.00082 19.1 0.0 2.6 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein tRNA_SAD PF07973.14 CBY35358.1 - 0.0073 16.4 0.6 2.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Threonyl and Alanyl tRNA synthetase second additional domain SET PF00856.28 CBY35359.1 - 2.5e-18 67.1 4.5 2.7e-18 66.9 0.1 2.4 2 1 0 2 2 2 1 SET domain Y2_Tnp PF04986.13 CBY35359.1 - 0.054 13.5 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative transposase LisH PF08513.11 CBY35360.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 LisH Methyltr_RsmB-F PF01189.17 CBY35362.1 - 2.7e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 CBY35362.1 - 0.0023 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.19 CBY35362.1 - 0.0031 17.7 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pet191_N PF10203.9 CBY35363.1 - 1.9e-07 31.3 1.2 2.9e-07 30.7 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PilW PF16074.5 CBY35363.1 - 0.0062 16.6 0.7 0.15 12.1 0.1 2.1 2 0 0 2 2 2 2 Type IV Pilus-assembly protein W NRBF2 PF08961.10 CBY35364.1 - 0.0048 16.5 0.4 0.0048 16.5 0.4 1.8 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator DivIC PF04977.15 CBY35364.1 - 0.11 12.3 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Ras PF00071.22 CBY35366.1 - 3.5e-14 52.7 0.0 3.1e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 Ras family EF_assoc_2 PF08356.12 CBY35366.1 - 2.5e-10 40.2 0.0 4.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 CBY35366.1 - 5.3e-10 39.5 0.1 2.9e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF_assoc_1 PF08355.12 CBY35366.1 - 4.4e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 EF hand associated EF-hand_6 PF13405.6 CBY35366.1 - 0.0048 16.7 0.3 0.19 11.7 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY35366.1 - 0.0065 15.9 0.2 0.059 12.9 0.1 2.6 2 0 0 2 2 2 1 EF hand MMR_HSR1 PF01926.23 CBY35366.1 - 0.042 13.9 0.1 0.18 11.9 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY35366.1 - 0.043 14.2 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBY35366.1 - 0.043 13.7 0.2 0.55 10.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 CBY35366.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CBY35366.1 - 0.07 12.6 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 CBY35366.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBY35366.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SURF4 PF02077.15 CBY35367.1 - 1.9e-93 312.9 8.6 2.4e-93 312.6 8.6 1.0 1 0 0 1 1 1 1 SURF4 family SURF2 PF05477.11 CBY35367.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) PRA1 PF03208.19 CBY35367.1 - 0.012 15.3 2.1 0.012 15.3 2.1 2.0 1 1 1 2 2 2 0 PRA1 family protein Phosphodiest PF01663.22 CBY35368.1 - 3.7e-57 194.6 0.1 6.5e-57 193.7 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Somatomedin_B PF01033.17 CBY35368.1 - 1.9e-05 24.9 10.4 4.2e-05 23.8 10.4 1.6 1 0 0 1 1 1 1 Somatomedin B domain Sulfatase PF00884.23 CBY35368.1 - 0.0043 16.5 0.0 0.021 14.2 0.0 2.2 1 1 0 1 1 1 1 Sulfatase CUT PF02376.15 CBY35369.1 - 5.6e-31 106.5 0.3 1e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CBY35369.1 - 4.4e-11 42.5 0.6 1e-10 41.3 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY35369.1 - 0.0004 20.2 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Auts2 PF15336.6 CBY35369.1 - 0.025 14.7 2.6 0.045 13.9 2.6 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein HNF-1_N PF04814.13 CBY35369.1 - 0.93 10.1 5.3 0.26 11.9 1.6 1.9 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus AMP-binding PF00501.28 CBY35370.1 - 1e-29 103.4 0.0 3.5e-29 101.6 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_S19 PF00203.21 CBY35371.1 - 7.2e-30 102.7 0.1 1e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FKBP_C PF00254.28 CBY35372.1 - 3.1e-33 114.0 0.1 6e-29 100.2 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 CBY35372.1 - 2e-08 33.7 0.7 0.0025 17.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY35372.1 - 5.5e-06 26.1 0.3 0.073 13.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY35372.1 - 9e-06 25.3 0.0 0.88 9.3 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CBY35372.1 - 1e-05 25.3 2.1 0.091 13.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY35372.1 - 0.014 16.0 0.1 1.9 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY35372.1 - 0.053 14.2 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBY35372.1 - 0.14 12.5 1.0 0.38 11.1 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY35372.1 - 0.67 10.1 2.2 0.69 10.0 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 UCH PF00443.29 CBY35373.1 - 1.2e-19 70.9 1.2 2.9e-14 53.2 0.0 2.7 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CBY35373.1 - 1.3e-10 41.4 6.5 2.5e-10 40.5 6.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CBY35373.1 - 0.36 10.6 2.7 0.7 9.7 2.7 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger ATP-synt_ab PF00006.25 CBY35374.1 - 4.6e-109 363.0 0.0 6.6e-109 362.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBY35374.1 - 8.9e-43 145.0 0.0 1.6e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBY35374.1 - 9.1e-16 58.1 1.4 2.1e-15 57.0 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain PSD4 PF07631.11 CBY35374.1 - 0.08 13.5 0.2 0.23 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) DUF3418 PF11898.8 CBY35374.1 - 0.18 10.5 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Brix PF04427.18 CBY35375.1 - 2.2e-20 73.6 0.3 4.2e-20 72.7 0.3 1.5 1 0 0 1 1 1 1 Brix domain FAM60A PF15396.6 CBY35375.1 - 0.081 12.9 1.4 0.15 12.0 1.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF3340 PF11818.8 CBY35375.1 - 0.094 12.9 9.6 0.19 11.9 9.6 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) MAM PF00629.23 CBY35377.1 - 0.0097 15.8 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu BaxI_1 PF12811.7 CBY35377.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF5305 PF17231.2 CBY35379.1 - 0.041 13.3 0.7 0.057 12.8 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) COesterase PF00135.28 CBY35380.1 - 5.2e-10 38.8 0.1 5.7e-10 38.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family AAA_5 PF07728.14 CBY35380.1 - 0.038 14.0 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3810 PF12725.7 CBY35381.1 - 0.089 12.1 2.8 0.14 11.5 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Tetraspanin PF00335.20 CBY35381.1 - 0.12 12.1 5.2 0.14 11.8 5.2 1.2 1 0 0 1 1 1 0 Tetraspanin family TMEM192 PF14802.6 CBY35381.1 - 0.22 10.6 2.6 0.18 10.9 1.1 1.6 1 1 0 1 1 1 0 TMEM192 family DUF2157 PF09925.9 CBY35381.1 - 1.2 9.0 7.2 2.9 7.7 6.8 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 CBY35381.1 - 4 6.1 8.6 1e+02 1.5 8.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Vma12 PF11712.8 CBY35381.1 - 5.6 7.0 6.1 1.4 8.9 1.7 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase V-ATPase_G PF03179.15 CBY35382.1 - 3.7e-27 94.9 17.4 4.1e-27 94.8 17.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3828 PF12883.7 CBY35382.1 - 0.046 14.1 2.0 0.067 13.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Inhibitor_I71 PF12628.7 CBY35382.1 - 0.058 13.2 0.8 0.076 12.9 0.8 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor OmpH PF03938.14 CBY35382.1 - 0.085 13.2 14.7 0.11 12.8 14.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FdhE PF04216.12 CBY35382.1 - 0.26 11.1 2.7 0.31 10.9 2.7 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DDE_Tnp_ISAZ013 PF07592.11 CBY35382.1 - 0.32 10.0 3.4 0.33 9.9 3.4 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF1690 PF07956.11 CBY35382.1 - 0.38 11.2 10.3 0.62 10.5 10.3 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Atg14 PF10186.9 CBY35382.1 - 0.51 9.4 8.3 0.61 9.1 8.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBY35382.1 - 0.68 9.2 8.6 0.97 8.7 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_22 PF18833.1 CBY35382.1 - 0.73 10.0 6.1 0.47 10.6 0.5 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat LprI PF07007.12 CBY35382.1 - 0.77 10.5 5.3 1.2 9.8 4.7 1.6 1 1 1 2 2 2 0 Lysozyme inhibitor LprI DUF16 PF01519.16 CBY35382.1 - 0.9 10.1 11.5 0.29 11.6 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 eIF3_N PF09440.10 CBY35382.1 - 0.93 9.9 7.4 0.98 9.9 6.2 1.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain RAI1 PF08652.11 CBY35382.1 - 0.98 9.7 3.6 1.4 9.2 3.6 1.4 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease RRF PF01765.19 CBY35382.1 - 1.7 8.6 15.9 1.3 9.0 14.7 1.4 1 1 0 1 1 1 0 Ribosome recycling factor HIP1_clath_bdg PF16515.5 CBY35382.1 - 2.4 8.8 12.3 6.1 7.5 10.7 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-ATPase_G_2 PF16999.5 CBY35382.1 - 3.5 8.1 14.7 15 6.1 14.7 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HSCB_C PF07743.13 CBY35382.1 - 5.2 7.6 10.9 2 9.0 0.3 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ATP-synt_B PF00430.18 CBY35382.1 - 7.4 6.7 18.8 62 3.7 18.8 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) I-set PF07679.16 CBY35383.1 - 2.1e-79 261.7 8.4 2.8e-16 59.3 0.0 7.7 7 0 0 7 7 7 7 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY35383.1 - 6.8e-46 154.8 0.3 3.5e-09 37.1 0.0 7.4 7 0 0 7 7 7 6 Immunoglobulin domain fn3 PF00041.21 CBY35383.1 - 2.3e-33 114.4 0.0 1.8e-12 47.4 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 CBY35383.1 - 7.8e-21 74.1 0.3 0.00028 21.0 0.0 6.9 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 CBY35383.1 - 2.9e-18 66.0 0.4 0.0014 18.9 0.0 6.8 7 0 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 CBY35383.1 - 1.6e-17 63.6 3.7 0.14 12.3 0.0 9.6 7 4 2 9 9 9 3 Immunoglobulin V-set domain THB PF18362.1 CBY35383.1 - 3.8e-10 39.2 0.3 1.2e-09 37.5 0.1 2.0 1 1 1 2 2 2 1 Tri-helix bundle domain Receptor_2B4 PF11465.8 CBY35383.1 - 2.8e-08 33.9 0.6 0.028 14.6 0.0 5.3 5 1 0 5 5 5 2 Natural killer cell receptor 2B4 Herpes_gI PF01688.17 CBY35383.1 - 1.8e-05 24.7 0.1 0.5 10.3 0.0 3.9 4 0 0 4 4 3 1 Alphaherpesvirus glycoprotein I Pur_ac_phosph_N PF16656.5 CBY35383.1 - 0.00054 20.5 0.0 0.44 11.2 0.0 4.1 3 1 1 4 4 3 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CBY35383.1 - 0.0013 18.2 0.0 11 5.7 0.0 4.4 5 0 0 5 5 5 1 Immunoglobulin domain C2-set_2 PF08205.12 CBY35383.1 - 0.0014 18.7 0.1 4 7.6 0.0 4.2 4 0 0 4 4 4 1 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CBY35383.1 - 0.047 14.1 4.0 72 3.9 0.1 4.6 5 0 0 5 5 5 0 Immunoglobulin C1-set domain LPD3 PF18798.1 CBY35383.1 - 0.066 13.5 0.1 22 5.3 0.0 3.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 MG2 PF01835.19 CBY35383.1 - 0.069 13.6 0.0 51 4.4 0.0 4.2 4 0 0 4 4 4 0 MG2 domain MBG_2 PF18676.1 CBY35383.1 - 0.11 13.2 0.0 15 6.3 0.0 3.9 3 0 0 3 3 3 0 MBG domain (YGX type) zf-H2C2_2 PF13465.6 CBY35384.1 - 7.7e-09 35.6 1.7 7.7e-09 35.6 1.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY35384.1 - 0.0093 16.4 0.3 0.0093 16.4 0.3 4.5 4 0 0 4 4 4 1 Zinc finger, C2H2 type CpXC PF14353.6 CBY35384.1 - 2.2 8.4 8.3 16 5.5 8.3 2.0 1 1 0 1 1 1 0 CpXC protein Ifi-6-16 PF06140.13 CBY35385.1 - 3.8e-06 26.7 1.1 6e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Homeodomain PF00046.29 CBY35386.1 - 3e-20 71.8 1.6 7.2e-20 70.6 1.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY35386.1 - 0.016 15.1 0.3 0.033 14.1 0.3 1.5 1 0 0 1 1 1 0 Homeobox KN domain DUF2013 PF09431.10 CBY35387.1 - 9.2e-28 97.1 3.3 2.2e-27 95.9 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) SH3_1 PF00018.28 CBY35387.1 - 2.5e-08 33.4 0.0 4.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY35387.1 - 2.7e-07 30.3 0.1 5.7e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY35387.1 - 4.8e-05 22.9 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MMS22L_C PF14911.6 CBY35387.1 - 0.0079 15.3 1.0 0.015 14.4 1.0 1.4 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal TIP120 PF08623.10 CBY35387.1 - 0.008 16.0 1.7 0.03 14.1 0.1 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Adaptin_binding PF10199.9 CBY35387.1 - 0.021 15.4 0.0 0.15 12.7 0.0 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 hSH3 PF14603.6 CBY35387.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Helically-extended SH3 domain SH3_3 PF08239.11 CBY35387.1 - 0.16 12.2 0.1 0.36 11.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Neprosin PF03080.15 CBY35387.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Neprosin zf-AD PF07776.15 CBY35387.1 - 0.31 11.3 1.7 1.4 9.2 1.6 2.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DUF2207 PF09972.9 CBY35388.1 - 0.04 12.7 0.1 0.04 12.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MukB_hinge PF16330.5 CBY35388.1 - 0.046 13.4 1.3 0.071 12.8 1.3 1.2 1 0 0 1 1 1 0 MukB hinge domain Mtp PF03821.16 CBY35388.1 - 0.047 13.3 2.9 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF2080 PF09853.9 CBY35388.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) Comm PF15957.5 CBY35389.1 - 0.26 11.6 1.3 0.45 10.9 1.3 1.3 1 0 0 1 1 1 0 Commissureless FAM176 PF14851.6 CBY35389.1 - 0.33 10.6 2.0 0.23 11.1 0.7 1.5 2 0 0 2 2 2 0 FAM176 family SURF6 PF04935.12 CBY35393.1 - 3.5e-33 115.1 58.2 6e-33 114.3 58.2 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 RRP14 PF15459.6 CBY35393.1 - 0.0091 16.6 0.0 0.0091 16.6 0.0 5.8 3 2 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 FA_desaturase PF00487.24 CBY35394.1 - 5.2e-13 49.4 10.4 1.1e-12 48.4 10.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBY35394.1 - 1.2e-11 44.6 0.1 2.2e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Phospholip_A2_1 PF00068.19 CBY35396.1 - 4.2e-14 53.0 3.8 4.2e-14 53.0 3.8 2.4 3 0 0 3 3 3 1 Phospholipase A2 WD40_like PF17005.5 CBY35397.1 - 2.3e-05 23.9 0.9 0.00072 19.0 0.1 2.8 2 1 1 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 CBY35397.1 - 2.9e-05 24.3 0.4 0.66 10.3 0.0 3.4 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY35397.1 - 0.00023 21.9 2.2 0.021 15.7 0.1 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat MMR_HSR1 PF01926.23 CBY35398.1 - 2e-09 37.6 0.0 5.8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY35398.1 - 2.1e-05 24.1 0.0 7.4e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 CBY35398.1 - 0.0047 17.5 0.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY35398.1 - 0.012 16.1 0.1 0.034 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 CBY35398.1 - 0.015 15.2 0.0 0.07 13.0 0.0 2.0 1 1 0 1 1 1 0 RsgA GTPase MCM PF00493.23 CBY35398.1 - 0.059 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain cobW PF02492.19 CBY35398.1 - 0.093 12.3 0.0 5.5 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 CBY35398.1 - 0.094 12.1 0.1 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Arf PF00025.21 CBY35398.1 - 0.13 11.7 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 CBY35398.1 - 0.17 10.9 0.1 6.1 5.7 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2085 PF09858.9 CBY35400.1 - 1.6 9.2 5.8 0.52 10.8 2.2 2.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) IBR PF01485.21 CBY35401.1 - 0.026 14.7 5.8 0.043 14.0 5.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ComX PF05952.12 CBY35401.1 - 0.086 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus competence pheromone ComX FYVE_2 PF02318.16 CBY35401.1 - 0.21 11.8 8.6 0.8 9.9 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-NADH-PPase PF09297.11 CBY35401.1 - 0.26 11.0 0.6 0.26 11.0 0.6 3.3 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RecR PF02132.15 CBY35401.1 - 1.6 8.4 7.3 1.6 8.3 0.2 2.7 2 1 0 2 2 2 0 RecR protein Fz PF01392.22 CBY35402.1 - 6.3e-22 78.3 1.1 6.3e-22 78.3 1.1 1.8 2 0 0 2 2 2 1 Fz domain NTR PF01759.21 CBY35402.1 - 0.081 12.7 3.4 0.19 11.5 3.4 1.7 1 1 0 1 1 1 0 UNC-6/NTR/C345C module NAGidase PF07555.13 CBY35404.1 - 8.6e-79 264.9 0.0 1.9e-78 263.8 0.0 1.5 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase PDCD9 PF07147.12 CBY35405.1 - 1.7e-22 80.3 0.0 2.4e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) Glyco_transf_90 PF05686.12 CBY35406.1 - 1.1e-59 202.3 0.3 1.6e-59 201.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 CBY35406.1 - 0.052 14.4 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat Pribosyltran PF00156.27 CBY35407.1 - 4.6e-21 75.0 0.0 6.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBY35407.1 - 0.005 16.3 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBY35407.1 - 0.051 13.1 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Opi1 PF08618.10 CBY35407.1 - 0.056 12.7 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 PRTase_3 PF15610.6 CBY35407.1 - 0.081 12.2 0.1 0.29 10.3 0.1 1.7 2 0 0 2 2 2 0 PRTase ComF-like PCI PF01399.27 CBY35408.1 - 0.034 14.7 0.1 0.13 12.8 0.1 2.1 1 0 0 1 1 1 0 PCI domain BIR PF00653.21 CBY35409.1 - 2.1e-33 114.8 4.8 2.2e-17 63.5 0.3 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain zf-C3HC4_3 PF13920.6 CBY35409.1 - 1.6e-11 43.9 8.9 1.6e-11 43.9 8.9 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY35409.1 - 2.3e-06 27.4 8.5 8.3e-06 25.6 8.5 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY35409.1 - 0.0055 17.0 10.7 0.0055 17.0 10.7 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY35409.1 - 0.0074 16.2 8.4 0.0074 16.2 8.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain DUF3954 PF13128.6 CBY35410.1 - 0.063 13.1 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3954) Kelch_2 PF07646.15 CBY35411.1 - 0.0015 18.5 0.9 0.47 10.5 0.1 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY35411.1 - 0.0024 18.1 2.0 0.19 12.1 0.0 4.0 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CBY35411.1 - 0.022 14.8 0.9 5.6 7.0 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF1254 PF06863.12 CBY35412.1 - 1.1e-15 57.8 0.0 4.3e-14 52.7 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 CBY35412.1 - 4.2e-13 49.7 0.1 5.1e-11 43.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) DUF4322 PF14210.6 CBY35412.1 - 0.092 12.7 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) HlyIII PF03006.20 CBY35414.1 - 1.4e-62 211.3 20.3 1.7e-62 211.1 20.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.18 CBY35414.1 - 0.00054 19.9 0.6 0.00075 19.4 0.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CBY35414.1 - 0.15 12.6 6.4 0.16 12.5 3.7 2.0 1 1 1 2 2 2 0 YtxH-like protein HLH PF00010.26 CBY35415.1 - 6.2e-12 45.3 0.1 1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L39 PF00832.20 CBY35416.1 - 0.00047 19.7 5.3 0.00057 19.5 3.3 2.1 1 1 1 2 2 2 1 Ribosomal L39 protein BCDHK_Adom3 PF10436.9 CBY35421.1 - 6.2e-17 61.9 0.5 9.9e-17 61.2 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBY35421.1 - 8e-10 39.2 0.0 2.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY35421.1 - 3e-05 23.9 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CBY35421.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF447 PF04289.12 CBY35421.1 - 0.039 13.7 0.3 0.076 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF447) PARP PF00644.20 CBY35422.1 - 2.9e-40 138.0 0.6 6.5e-40 136.8 0.6 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CBY35422.1 - 2.1e-29 102.3 1.5 2.1e-29 102.3 1.5 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CBY35422.1 - 0.009 16.1 0.9 0.037 14.1 0.9 2.1 1 1 0 1 1 1 1 WGR domain PUF PF00806.19 CBY35422.1 - 0.036 13.8 1.3 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DUF1664 PF07889.12 CBY35422.1 - 9.3 6.3 22.2 4.1 7.5 5.9 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 CBY35423.1 - 0.0014 18.8 6.7 0.031 14.4 6.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2959) partial_CstF PF15861.5 CBY35423.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF1054 PF06335.12 CBY35423.1 - 0.016 15.1 2.8 0.22 11.4 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1054) CENP-F_leu_zip PF10473.9 CBY35423.1 - 0.021 14.9 1.3 0.021 14.9 1.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 CBY35423.1 - 0.039 14.2 14.9 0.073 13.3 14.9 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Bap31_Bap29_C PF18035.1 CBY35423.1 - 0.084 12.9 0.5 0.084 12.9 0.5 2.1 3 0 0 3 3 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain MIS13 PF08202.11 CBY35423.1 - 0.16 11.3 10.4 0.11 11.7 9.3 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family MYO10_CC PF16735.5 CBY35423.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.8 2 2 1 3 3 3 0 Unconventional myosin-X coiled coil domain TEX13 PF15186.6 CBY35423.1 - 0.2 11.4 7.7 0.29 10.8 7.7 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family T3SS_needle_F PF09392.10 CBY35423.1 - 0.26 11.5 6.2 0.59 10.4 0.2 3.2 2 1 1 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Tweety PF04906.13 CBY35423.1 - 0.32 9.6 5.9 0.52 8.9 4.9 1.7 1 1 1 2 2 2 0 Tweety DUF4988 PF16378.5 CBY35423.1 - 0.39 10.4 4.8 1.7 8.3 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function FlaC_arch PF05377.11 CBY35423.1 - 0.44 11.0 11.1 0.38 11.2 1.0 3.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CBY35423.1 - 0.47 10.5 8.5 0.21 11.6 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 CBY35423.1 - 0.9 9.4 10.2 0.33 10.8 6.1 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF2703 PF10865.8 CBY35423.1 - 0.94 9.7 3.8 1.8 8.8 0.8 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) Baculo_PEP_C PF04513.12 CBY35423.1 - 0.95 9.5 9.1 0.67 10.0 6.8 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 CBY35423.1 - 0.96 9.5 12.6 2 8.5 12.2 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) UPF0242 PF06785.11 CBY35423.1 - 1.4 9.0 16.6 2.4 8.2 3.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus hDGE_amylase PF14701.6 CBY35423.1 - 1.6 7.7 7.2 1.9 7.5 7.2 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain CLZ PF16526.5 CBY35423.1 - 2.1 8.7 8.8 1 9.8 0.8 2.9 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 CBY35423.1 - 2.1 7.8 8.8 2.5 7.6 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 CBY35423.1 - 3.6 7.9 7.6 45 4.4 5.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 CBY35423.1 - 5.7 7.6 11.4 8.2 7.1 2.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Matrilin_ccoil PF10393.9 CBY35423.1 - 6.7 6.7 10.3 0.84 9.5 0.9 3.1 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF745 PF05335.13 CBY35423.1 - 7.9 6.2 7.5 1.6 8.4 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PspB PF06667.12 CBY35423.1 - 8.6 6.5 6.2 23 5.1 0.4 2.5 2 1 0 2 2 2 0 Phage shock protein B Prominin PF05478.11 CBY35423.1 - 9 4.1 11.4 4.2 5.2 1.9 1.5 1 1 1 2 2 2 0 Prominin Atg14 PF10186.9 CBY35423.1 - 9.1 5.3 12.0 1e+02 1.8 12.0 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Apolipoprotein PF01442.18 CBY35424.1 - 0.11 12.3 36.7 0.5 10.2 13.7 3.2 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain AAA_13 PF13166.6 CBY35424.1 - 3 6.4 51.2 2.1 6.9 20.1 2.0 1 1 1 2 2 2 0 AAA domain DUF948 PF06103.11 CBY35424.1 - 3 8.1 25.8 1.6 9.0 4.7 4.6 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 CBY35424.1 - 8.4 6.5 52.6 0.047 13.8 9.3 3.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 CBY35424.1 - 9 3.7 50.6 3.7 5.0 37.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FAM163 PF15069.6 CBY35425.1 - 1.7e-08 35.1 0.2 1.9e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 FAM163 family FixQ PF05545.11 CBY35425.1 - 0.0053 16.7 0.1 0.0085 16.0 0.1 1.3 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ 7TM_GPCR_Srv PF10323.9 CBY35425.1 - 0.0083 15.5 0.9 0.012 15.0 0.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 CBY35425.1 - 0.017 15.4 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator P_proprotein PF01483.20 CBY35425.1 - 0.058 13.4 0.0 0.085 12.9 0.0 1.3 1 1 0 1 1 1 0 Proprotein convertase P-domain LST1 PF05083.13 CBY35425.1 - 1.6 9.1 4.3 2.8 8.3 4.1 1.6 1 1 0 1 1 1 0 LST-1 protein TMEM65 PF10507.9 CBY35427.1 - 1.2e-43 147.5 0.6 1.5e-43 147.1 0.6 1.1 1 0 0 1 1 1 1 Transmembrane protein 65 Forkhead PF00250.18 CBY35428.1 - 5.1e-38 129.2 0.1 1.3e-37 127.9 0.1 1.7 2 0 0 2 2 2 1 Forkhead domain Ion_trans_2 PF07885.16 CBY35429.1 - 1.6e-07 31.2 7.5 3e-07 30.3 7.5 1.4 1 0 0 1 1 1 1 Ion channel CDC14 PF08045.11 CBY35429.1 - 0.019 14.1 3.3 0.035 13.2 3.3 1.4 1 0 0 1 1 1 0 Cell division control protein 14, SIN component LPP PF04728.13 CBY35429.1 - 0.033 14.6 0.5 0.033 14.6 0.5 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ASD2 PF08687.11 CBY35429.1 - 0.036 13.6 12.8 0.43 10.1 8.8 2.2 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 DUF2985 PF11204.8 CBY35429.1 - 0.037 14.2 0.5 0.093 12.9 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) CaMBD PF02888.16 CBY35429.1 - 0.49 10.6 3.8 3.7 7.8 3.8 2.4 1 1 0 1 1 1 0 Calmodulin binding domain Baculo_p24 PF05073.12 CBY35429.1 - 1.4 8.7 6.3 0.65 9.8 2.2 2.3 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Spectrin PF00435.21 CBY35429.1 - 6.2 7.4 8.3 0.72 10.4 2.3 2.5 3 1 0 3 3 3 0 Spectrin repeat Sulfotransfer_2 PF03567.14 CBY35430.1 - 6.2e-13 49.2 0.5 2.7e-12 47.1 0.2 1.9 2 0 0 2 2 2 1 Sulfotransferase family Jnk-SapK_ap_N PF09744.9 CBY35431.1 - 7.2e-05 23.1 13.3 7.2e-05 23.1 13.3 3.3 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 RILP PF11461.8 CBY35431.1 - 0.0001 22.5 2.8 0.0001 22.5 2.8 3.6 4 0 0 4 4 4 1 Rab interacting lysosomal protein DUF641 PF04859.12 CBY35431.1 - 0.011 16.1 5.3 0.011 16.1 5.3 2.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 CBY35431.1 - 3.7 7.6 26.7 0.65 10.1 16.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Arginosuc_synth PF00764.19 CBY35432.1 - 6.3e-155 516.2 0.0 7.2e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CBY35432.1 - 0.0015 18.1 0.0 0.0033 16.9 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CBY35432.1 - 0.01 14.7 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 tRNA methyl transferase HCO3_cotransp PF00955.21 CBY35433.1 - 2.9e-143 478.4 1.1 4.2e-143 477.8 1.1 1.2 1 0 0 1 1 1 1 HCO3- transporter family Xan_ur_permease PF00860.20 CBY35433.1 - 0.00019 20.2 4.6 0.00019 20.2 4.6 3.3 4 1 1 5 5 5 2 Permease family CD20 PF04103.15 CBY35434.1 - 0.00018 21.6 9.3 0.13 12.4 6.5 2.3 1 1 0 2 2 2 2 CD20-like family DUF4064 PF13273.6 CBY35434.1 - 0.0023 18.2 9.4 0.087 13.1 6.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 CBY35434.1 - 0.0052 16.5 15.0 0.042 13.5 15.0 1.9 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 CBY35434.1 - 0.011 15.5 3.3 0.011 15.5 3.3 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3671 PF12420.8 CBY35434.1 - 4.3 7.4 10.0 0.3 11.2 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function S_layer_N PF05123.12 CBY35437.1 - 0.039 13.8 0.8 0.053 13.4 0.8 1.1 1 0 0 1 1 1 0 S-layer like family, N-terminal region Phage_Coat_Gp8 PF05371.12 CBY35437.1 - 0.1 12.4 0.6 0.16 11.7 0.6 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Trypsin PF00089.26 CBY35438.1 - 6.9e-47 160.1 0.8 8.1e-47 159.9 0.8 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY35438.1 - 0.0012 19.7 0.0 0.0025 18.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY35438.1 - 0.011 16.1 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Galactosyl_T PF01762.21 CBY35439.1 - 8.3e-35 120.4 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY35439.1 - 6.7 7.3 10.4 6.6 7.3 5.7 2.5 2 0 0 2 2 2 0 Chitin recognition protein Na_H_Exchanger PF00999.21 CBY35440.1 - 7.5e-61 206.0 23.2 1e-60 205.6 23.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NEXCaM_BD PF16644.5 CBY35440.1 - 0.096 12.9 8.6 0.2 11.9 8.6 1.4 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Pkinase PF00069.25 CBY35442.1 - 3.2e-58 197.2 0.0 3.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35442.1 - 3.4e-21 75.7 0.0 4.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY35442.1 - 4.1e-07 29.6 0.0 5.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY35442.1 - 1.6e-06 27.6 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY35442.1 - 0.035 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CBY35442.1 - 0.056 13.4 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY35442.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2070 PF09843.9 CBY35443.1 - 3.7 5.7 6.6 4 5.6 6.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Aa_trans PF01490.18 CBY35444.1 - 1.8e-74 250.9 34.3 4.9e-41 140.8 12.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Lipocalin PF00061.23 CBY35445.1 - 0.0082 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_7 PF14651.6 CBY35445.1 - 0.049 13.6 0.1 0.066 13.2 0.1 1.3 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Myosin_head PF00063.21 CBY35447.1 - 1e-262 873.4 1.5 4.8e-262 871.1 1.5 2.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY35447.1 - 5.9e-151 504.5 257.5 7.6e-151 504.2 257.5 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY35447.1 - 0.085 12.7 1.1 0.31 10.9 1.1 2.0 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 CBY35447.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY35447.1 - 0.16 12.2 0.0 0.16 12.2 0.0 5.1 6 1 0 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY35447.1 - 0.42 11.0 0.0 0.42 11.0 0.0 6.7 2 1 1 3 3 3 0 AAA ATPase domain HSBP1 PF06825.12 CBY35447.1 - 6 6.8 19.7 0.66 9.9 0.4 6.3 6 0 0 6 6 6 0 Heat shock factor binding protein 1 Phospholip_A2_1 PF00068.19 CBY35448.1 - 5.5e-17 62.3 11.2 9.9e-17 61.4 11.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.8 CBY35450.1 - 1.2e-13 51.9 15.1 1.2e-13 51.9 15.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) BUD22 PF09073.10 CBY35451.1 - 1.4 8.2 13.6 1.9 7.7 13.6 1.1 1 0 0 1 1 1 0 BUD22 EF-hand_1 PF00036.32 CBY35452.1 - 6.2e-21 72.3 7.0 0.0006 19.2 0.3 5.9 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 CBY35452.1 - 1e-17 62.7 5.3 0.00052 19.4 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY35452.1 - 1.7e-15 55.6 9.3 0.029 14.3 0.0 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY35452.1 - 1.9e-15 57.1 19.2 1e-09 38.7 0.5 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CBY35452.1 - 5.2e-07 29.4 18.3 0.033 14.0 0.0 5.3 5 1 1 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY35452.1 - 0.0014 19.0 12.9 0.0022 18.3 0.4 3.4 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY35452.1 - 0.49 10.3 4.1 10 6.1 0.3 3.5 3 0 0 3 3 3 0 EF hand Dockerin_1 PF00404.18 CBY35452.1 - 1.5 9.0 5.0 5.5 7.3 0.1 3.5 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_4 PF12763.7 CBY35452.1 - 4.3 7.3 13.1 2.6 8.1 0.2 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.16 CBY35453.1 - 2.8e-55 187.5 0.0 3.2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY35453.1 - 4.6e-09 35.9 0.0 0.00023 20.5 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CBY35453.1 - 5.3e-07 29.3 0.1 0.037 13.5 0.0 2.6 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 CBY35453.1 - 4.4e-06 26.4 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBY35453.1 - 4.8e-06 26.4 0.0 2.6e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY35453.1 - 9.6e-06 26.4 0.0 1.2e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CBY35453.1 - 3.3e-05 23.7 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY35453.1 - 3.7e-05 23.5 0.0 4.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 CBY35453.1 - 0.0028 17.4 0.0 0.004 16.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 CBY35453.1 - 0.0037 17.1 0.0 0.02 14.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 CBY35453.1 - 0.064 12.2 0.0 0.064 12.2 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydro_lipase PF04083.16 CBY35453.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 CBY35453.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Ank_5 PF13857.6 CBY35454.1 - 1.3e-10 41.3 0.0 4.5e-10 39.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY35454.1 - 1.9e-10 41.1 0.7 6.2e-05 23.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35454.1 - 3.6e-08 33.9 0.1 1.1e-07 32.3 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY35454.1 - 4.1e-07 30.2 0.1 9.7e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 CBY35454.1 - 6.9e-07 29.1 0.1 2.4e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat HTH_ABP1_N PF18107.1 CBY35454.1 - 0.0015 18.2 0.2 0.0037 17.0 0.2 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Mad3_BUB1_I PF08311.12 CBY35454.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Thiolase_N PF00108.23 CBY35455.1 - 2.2e-89 299.3 5.5 3.2e-89 298.7 5.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY35455.1 - 2.3e-43 146.7 3.2 2.5e-43 146.7 0.3 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY35455.1 - 4.3e-05 23.2 4.4 0.00048 19.8 4.3 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBY35455.1 - 9.5 6.2 6.9 16 5.4 0.6 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioredoxin PF00085.20 CBY35456.1 - 2e-09 37.3 0.4 3.8e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Phosducin PF02114.16 CBY35456.1 - 1.1e-07 31.1 0.6 1.2e-07 31.0 0.6 1.0 1 0 0 1 1 1 1 Phosducin DUF3037 PF11236.8 CBY35456.1 - 0.054 13.9 0.2 0.085 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) adh_short PF00106.25 CBY35458.1 - 1.1e-22 80.4 0.5 4.8e-19 68.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY35458.1 - 7.6e-15 55.1 2.2 5.1e-13 49.1 0.6 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY35458.1 - 2.2e-07 31.0 0.1 4.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY35458.1 - 0.00082 18.9 0.2 0.0011 18.5 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY35458.1 - 0.0071 16.3 0.3 0.01 15.7 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CBY35458.1 - 0.026 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 CBY35458.1 - 0.084 12.6 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.16 CBY35459.1 - 1e-29 103.6 13.1 1.6e-29 103.0 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 CBY35459.1 - 1.3 8.8 4.3 0.89 9.4 0.5 2.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Sulfotransfer_1 PF00685.27 CBY35460.1 - 6.8e-09 35.6 0.4 5.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY35460.1 - 5.1e-05 23.8 0.0 8.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family LRR_8 PF13855.6 CBY35461.1 - 1.1e-62 207.6 72.0 2.4e-12 46.4 3.7 11.0 5 4 7 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 CBY35461.1 - 1.5e-31 107.9 81.6 2.4e-06 27.7 1.1 12.6 10 1 3 13 13 13 11 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY35461.1 - 1.3e-22 80.2 18.2 2e-06 27.8 0.2 5.5 6 0 0 6 6 6 4 BspA type Leucine rich repeat region (6 copies) EGF PF00008.27 CBY35461.1 - 4.6e-19 68.4 131.2 2.5e-07 30.9 6.1 12.5 12 1 0 12 12 11 7 EGF-like domain LRR_9 PF14580.6 CBY35461.1 - 2.2e-18 66.4 33.4 6.3e-06 25.8 1.7 6.6 4 3 3 7 7 7 6 Leucine-rich repeat Laminin_G_1 PF00054.23 CBY35461.1 - 2.2e-12 47.3 0.1 3.6e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 CBY35461.1 - 3.3e-11 43.8 0.0 6.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain LRR_1 PF00560.33 CBY35461.1 - 3.8e-05 23.6 51.9 3 8.8 0.2 15.0 16 0 0 16 16 15 2 Leucine Rich Repeat LRRCT PF01463.24 CBY35461.1 - 0.00018 21.8 0.4 18 6.2 0.0 4.3 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain hEGF PF12661.7 CBY35461.1 - 0.00056 20.5 5.5 0.00056 20.5 5.5 13.0 12 1 0 12 12 10 6 Human growth factor-like EGF EGF_2 PF07974.13 CBY35461.1 - 0.00069 19.9 9.1 0.00069 19.9 9.1 12.9 13 0 0 13 13 11 7 EGF-like domain EGF_CA PF07645.15 CBY35461.1 - 0.00076 19.6 5.9 0.00076 19.6 5.9 12.1 9 2 3 13 13 10 2 Calcium-binding EGF domain LRRNT PF01462.18 CBY35461.1 - 0.0051 16.4 3.4 0.0051 16.4 3.4 7.6 9 0 0 9 9 9 2 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 CBY35461.1 - 0.14 12.3 21.1 29 5.0 0.3 9.2 9 0 0 9 9 9 0 Leucine Rich repeat adh_short_C2 PF13561.6 CBY35462.1 - 3.4e-51 174.0 0.1 4.3e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY35462.1 - 2.8e-48 164.0 0.4 3.5e-48 163.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY35462.1 - 9.8e-15 54.9 0.2 1.5e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CBY35462.1 - 0.00066 18.9 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBY35462.1 - 0.0047 16.8 0.2 0.0059 16.5 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 CBY35462.1 - 0.0056 16.6 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CBY35462.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 CBY35462.1 - 0.13 11.6 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CBY35462.1 - 0.14 11.6 0.3 0.54 9.7 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FtsX_ECD PF18075.1 CBY35463.1 - 0.069 13.8 1.3 0.14 12.8 1.3 1.5 1 0 0 1 1 1 0 FtsX extracellular domain LMBR1 PF04791.16 CBY35463.1 - 0.33 9.8 1.0 0.33 9.8 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 CBY35463.1 - 0.51 8.2 7.5 0.67 7.8 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 2TM PF13239.6 CBY35464.1 - 0.038 14.3 1.3 0.071 13.4 1.3 1.4 1 0 0 1 1 1 0 2TM domain DUF3007 PF11460.8 CBY35464.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Na_sulph_symp PF00939.19 CBY35465.1 - 4.3e-20 72.2 8.1 5e-20 72.0 8.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY35465.1 - 3.7e-08 32.9 10.8 4e-08 32.8 10.8 1.0 1 0 0 1 1 1 1 Citrate transporter Glycogen_syn PF05693.13 CBY35466.1 - 1.3e-277 922.6 0.0 1.6e-277 922.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CBY35466.1 - 1.1e-08 34.8 0.0 0.00078 19.0 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY35466.1 - 1.4e-06 28.4 0.1 2.9e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CBY35466.1 - 5.1e-06 26.9 0.0 0.02 15.3 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Imm68 PF15583.6 CBY35466.1 - 0.085 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 68 ECH_1 PF00378.20 CBY35469.1 - 1.5e-30 106.3 0.0 1.8e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY35469.1 - 2.3e-08 33.9 0.0 2.7e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DJ-1_PfpI PF01965.24 CBY35469.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family TFIID_20kDa PF03847.13 CBY35469.1 - 0.053 14.0 0.1 7.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Pkinase PF00069.25 CBY35470.1 - 1.2e-66 224.8 0.0 2.5e-66 223.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35470.1 - 4.3e-29 101.6 0.0 7e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY35470.1 - 1.3e-05 24.7 0.2 0.00026 20.4 0.0 2.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY35470.1 - 0.0001 21.9 1.2 0.0002 21.0 0.1 2.0 2 0 0 2 2 2 1 RIO1 family Nsp1_C PF05064.13 CBY35470.1 - 0.031 14.1 2.3 0.21 11.4 1.2 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4534 PF15049.6 CBY35471.1 - 0.046 13.5 7.3 1.9 8.2 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) DUF4064 PF13273.6 CBY35471.1 - 0.064 13.5 9.7 0.26 11.6 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SfLAP PF11139.8 CBY35471.1 - 0.23 10.8 3.7 0.25 10.8 0.3 2.0 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein MFS_1 PF07690.16 CBY35472.1 - 0.012 14.6 1.0 0.017 14.1 0.9 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily Anoctamin PF04547.12 CBY35473.1 - 2.5e-65 221.1 15.1 3.1e-65 220.8 15.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3021 PF11457.8 CBY35473.1 - 0.011 16.1 1.5 0.011 16.1 1.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3021) Ctr PF04145.15 CBY35473.1 - 0.13 12.9 0.9 0.95 10.1 0.9 2.3 1 1 0 1 1 1 0 Ctr copper transporter family MotA_ExbB PF01618.16 CBY35473.1 - 0.16 11.7 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Ribosomal_L3 PF00297.22 CBY35473.1 - 0.21 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 ECF_trnsprt PF12822.7 CBY35473.1 - 3.6 7.7 13.0 0.12 12.5 3.9 2.7 1 1 2 3 3 3 0 ECF transporter, substrate-specific component Gp_dh_C PF02800.20 CBY35474.1 - 1.1e-70 236.2 0.0 1.7e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY35474.1 - 6.5e-40 135.6 0.2 1.6e-39 134.3 0.2 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBY35474.1 - 0.023 14.8 0.1 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DHR10 PF18595.1 CBY35475.1 - 0.0039 17.2 5.8 0.0078 16.3 5.8 1.5 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Membralin PF09746.9 CBY35475.1 - 0.017 14.2 1.3 0.018 14.1 1.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF4370 PF14290.6 CBY35475.1 - 0.068 13.0 0.2 0.087 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Shisa PF13908.6 CBY35476.1 - 0.012 15.9 5.3 0.076 13.3 5.3 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 CBY35476.1 - 0.02 15.9 0.2 0.061 14.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Orthoreo_P10 PF07204.11 CBY35476.1 - 0.025 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 FAM176 PF14851.6 CBY35476.1 - 0.072 12.7 0.4 0.18 11.4 0.4 1.6 1 1 0 1 1 1 0 FAM176 family TMIE PF16038.5 CBY35476.1 - 0.14 12.0 0.8 0.22 11.4 0.8 1.3 1 0 0 1 1 1 0 TMIE protein Pkinase PF00069.25 CBY35477.1 - 4.2e-41 141.1 0.0 5.9e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35477.1 - 1e-16 61.0 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY35477.1 - 2.6e-10 40.0 0.0 4.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY35477.1 - 6.4e-05 21.9 0.0 9.1e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY35477.1 - 0.00068 19.6 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY35477.1 - 0.00072 18.6 0.2 0.0011 18.0 0.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY35477.1 - 0.0067 16.0 0.3 0.009 15.6 0.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY35477.1 - 0.0094 15.3 0.0 0.026 13.8 0.0 1.7 2 1 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.6 CBY35479.1 - 5.5e-12 44.6 0.2 1.7e-06 27.5 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY35479.1 - 8.2e-12 43.8 2.8 5.5e-06 25.6 0.3 3.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY35479.1 - 4.5e-09 36.6 0.7 0.00013 22.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY35479.1 - 1.7e-06 27.8 3.2 0.016 15.1 0.1 3.3 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY35479.1 - 1.5e-05 24.3 0.8 1.5e-05 24.3 0.8 2.6 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.10 CBY35479.1 - 0.0067 16.5 0.4 0.33 11.1 0.1 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_4 PF12763.7 CBY35479.1 - 0.024 14.6 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 CBY35480.1 - 1.6e-53 180.6 0.0 1.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY35480.1 - 3.8e-26 91.7 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY35480.1 - 1.1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBY35480.1 - 0.00027 20.4 0.0 0.00036 20.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY35480.1 - 0.00045 19.8 0.1 0.00089 18.8 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY35480.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY35480.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ldh_1_N PF00056.23 CBY35480.1 - 0.067 13.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Pdase_M17_N2 PF18295.1 CBY35480.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 Lipase_GDSL_3 PF14606.6 CBY35480.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TniB PF05621.11 CBY35480.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Peptidase_M14 PF00246.24 CBY35481.1 - 5.5e-66 223.3 0.1 7.2e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Thioredoxin_7 PF13899.6 CBY35482.1 - 4.6e-07 29.9 0.1 7.3e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Lectin_C PF00059.21 CBY35483.1 - 1.5e-18 67.5 0.7 6.5e-18 65.4 0.7 2.1 1 0 0 1 1 1 1 Lectin C-type domain Copine PF07002.16 CBY35484.1 - 1.5e-78 263.3 0.1 2e-78 262.8 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CBY35484.1 - 1.6e-09 38.0 0.0 1e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain vWA-TerF-like PF10138.9 CBY35484.1 - 6.4e-05 23.1 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus PDZ PF00595.24 CBY35485.1 - 4.2e-10 39.9 0.1 6.6e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY35485.1 - 0.00039 20.2 0.0 0.0009 19.0 0.0 1.6 2 0 0 2 2 2 1 PDZ domain FKBP_C PF00254.28 CBY35487.1 - 8.5e-11 42.0 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2810 PF10928.8 CBY35487.1 - 0.17 11.9 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) 7tm_2 PF00002.24 CBY35488.1 - 7.9e-12 45.0 15.3 1.9e-11 43.7 15.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 CBY35488.1 - 5.4e-10 39.6 3.3 1.3e-09 38.5 3.3 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif 7tm_1 PF00001.21 CBY35488.1 - 5.1e-05 22.7 8.6 8e-05 22.1 8.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 CBY35488.1 - 0.036 12.9 2.3 1.1 8.0 1.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Caveolin PF01146.17 CBY35489.1 - 0.0072 16.3 3.4 0.011 15.6 3.4 1.2 1 0 0 1 1 1 1 Caveolin DUF4191 PF13829.6 CBY35489.1 - 6.1 6.1 5.5 1.2 8.4 2.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ycf70 PF17382.2 CBY35490.1 - 0.032 14.6 1.9 0.072 13.5 1.9 1.6 1 0 0 1 1 1 0 Uncharacterized Ycf70-like TagA PF12561.8 CBY35490.1 - 0.096 13.1 1.5 3.9 8.0 0.2 2.2 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain Casc1_N PF15927.5 CBY35490.1 - 0.16 11.6 7.7 0.29 10.8 7.7 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MT PF12777.7 CBY35491.1 - 1.3e-148 494.7 8.7 4.3e-115 384.4 6.7 2.5 1 1 1 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_6 PF12774.7 CBY35491.1 - 3.3e-99 332.0 1.7 3.5e-70 236.6 0.0 3.4 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CBY35491.1 - 1.3e-98 329.4 0.0 3.1e-98 328.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBY35491.1 - 5.6e-96 321.4 0.2 1.7e-95 319.8 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 CBY35491.1 - 2.6e-75 254.0 4.2 1e-66 225.7 0.0 2.9 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CBY35491.1 - 4.8e-54 182.6 1.4 1.4e-48 164.8 0.0 3.9 2 1 1 3 3 3 2 P-loop containing dynein motor region AAA_9 PF12781.7 CBY35491.1 - 1.3e-43 148.7 4.7 4.5e-32 111.0 0.0 3.1 2 1 1 3 3 3 2 ATP-binding dynein motor region AAA_lid_1 PF17857.1 CBY35491.1 - 2.6e-39 133.4 0.4 1.4e-38 131.1 0.4 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_lid_11 PF18198.1 CBY35491.1 - 9.9e-30 103.5 0.2 3.6e-28 98.4 0.0 2.9 2 1 1 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY35491.1 - 5.1e-19 68.5 0.0 6.6e-18 64.9 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBY35491.1 - 4.3e-13 49.5 0.8 1.1e-06 28.8 0.1 3.2 1 1 1 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY35491.1 - 0.00069 19.6 0.0 0.43 10.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY35491.1 - 0.0079 16.6 1.0 27 5.1 0.1 4.2 3 0 0 3 3 3 0 AAA ATPase domain POT1PC PF16686.5 CBY35491.1 - 0.05 13.5 0.2 0.3 11.0 0.0 2.3 3 0 0 3 3 3 0 ssDNA-binding domain of telomere protection protein Jnk-SapK_ap_N PF09744.9 CBY35491.1 - 0.38 11.0 8.6 1.2 9.4 3.3 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DHC_N1 PF08385.12 CBY35492.1 - 8.6e-81 272.3 0.6 8.6e-81 272.3 0.6 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 Spectrin PF00435.21 CBY35492.1 - 0.0078 16.7 1.3 0.94 10.0 0.0 3.5 3 0 0 3 3 3 1 Spectrin repeat DHC_N2 PF08393.13 CBY35492.1 - 0.012 14.8 1.1 0.012 14.8 1.1 4.1 3 1 1 4 4 4 0 Dynein heavy chain, N-terminal region 2 BAG6 PF12057.8 CBY35492.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF4363 PF14276.6 CBY35492.1 - 9 6.5 11.7 3.9 7.6 0.1 4.3 5 1 1 6 6 6 0 Domain of unknown function (DUF4363) HRM PF02793.22 CBY35493.1 - 0.022 15.1 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 Hormone receptor domain Innexin PF00876.18 CBY35494.1 - 0.0018 17.6 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Innexin WW_like PF17890.1 CBY35494.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Ion_trans PF00520.31 CBY35495.1 - 2.2e-21 76.2 23.0 2.9e-21 75.8 23.0 1.2 1 0 0 1 1 1 1 Ion transport protein ODV-E18 PF10717.9 CBY35495.1 - 0.28 11.1 5.2 0.87 9.5 0.0 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF4446 PF14584.6 CBY35495.1 - 4.1 7.4 12.0 0.15 12.0 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) Lactamase_B PF00753.27 CBY35496.1 - 2.7e-14 53.6 3.8 2.6e-12 47.1 3.8 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY35496.1 - 0.0056 16.2 1.1 0.01 15.4 1.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lipocalin_2 PF08212.12 CBY35497.1 - 1.8e-14 53.9 0.2 2.1e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CBY35497.1 - 9.7e-10 38.8 0.1 1.1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family OPT PF03169.15 CBY35498.1 - 0.024 13.3 0.0 0.026 13.1 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Kelch_1 PF01344.25 CBY35499.1 - 9.8e-05 21.9 0.1 0.17 11.5 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY35499.1 - 0.00029 21.0 1.0 0.57 10.5 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY35499.1 - 0.0037 17.3 1.1 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Flg_new PF09479.10 CBY35499.1 - 0.088 13.0 0.5 0.18 12.0 0.5 1.4 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Phospholip_A2_1 PF00068.19 CBY35500.1 - 8.4e-14 52.0 5.7 8.4e-14 52.0 5.7 2.1 1 1 1 2 2 2 1 Phospholipase A2 PP1_bind PF15276.6 CBY35500.1 - 0.031 14.6 0.1 0.062 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding Peptidase_C97 PF05903.14 CBY35501.1 - 2.8e-34 118.1 0.0 3.3e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PMP22_Claudin PF00822.20 CBY35504.1 - 2.2e-05 24.4 8.2 3.2e-05 23.9 8.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 CBY35504.1 - 5.4e-05 23.5 8.4 9.3e-05 22.7 8.4 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Claudin_2 PF13903.6 CBY35504.1 - 0.00046 20.0 5.0 0.00082 19.2 5.0 1.5 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 CBY35504.1 - 0.17 12.1 7.0 1.3 9.4 6.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2157 PF09925.9 CBY35504.1 - 0.22 11.3 0.2 0.22 11.3 0.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Pox_A14 PF05767.12 CBY35504.1 - 0.77 9.9 9.2 2 8.6 3.6 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MIG-14_Wnt-bd PF06664.12 CBY35504.1 - 3.3 6.9 14.8 12 5.1 14.9 2.0 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF202 PF02656.15 CBY35504.1 - 5.9 7.4 6.4 0.84 10.1 1.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Trypsin PF00089.26 CBY35505.1 - 3.2e-54 184.1 0.9 6.2e-54 183.1 0.9 1.5 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY35505.1 - 0.036 15.0 0.0 0.13 13.1 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain TSP_1 PF00090.19 CBY35506.1 - 4.3e-16 58.9 31.8 3.9e-11 43.0 11.2 3.1 3 1 0 3 3 3 2 Thrombospondin type 1 domain CAP PF00188.26 CBY35506.1 - 6.5e-16 59.3 0.5 1.4e-15 58.3 0.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RVT_1 PF00078.27 CBY35507.1 - 2.3e-26 92.7 0.0 5.9e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNARE_assoc PF09335.11 CBY35509.1 - 0.0084 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein Adeno_E3_CR2 PF02439.15 CBY35509.1 - 0.027 14.2 0.8 0.045 13.5 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4381 PF14316.6 CBY35509.1 - 0.24 11.6 1.2 0.39 11.0 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Sec7_N PF12783.7 CBY35510.1 - 9.7e-48 162.0 0.7 9.7e-48 162.0 0.7 4.5 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 CBY35510.1 - 1.3e-47 161.9 1.2 2e-24 86.3 0.2 3.2 2 1 1 3 3 3 2 Sec7 domain DUF1981 PF09324.10 CBY35510.1 - 5.6e-31 106.2 6.7 1.2e-29 102.0 0.0 5.3 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 CBY35510.1 - 1.3e-23 83.6 3.6 1.3e-23 83.6 3.6 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 TPR_1 PF00515.28 CBY35511.1 - 2.8e-53 175.7 36.0 7.9e-09 35.0 0.1 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 CBY35511.1 - 2.8e-44 145.7 31.1 1.3e-06 28.0 0.1 10.0 11 0 0 11 11 9 8 Tetratricopeptide repeat STI1 PF17830.1 CBY35511.1 - 1.8e-39 133.5 20.7 4.2e-21 74.6 2.9 2.6 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 CBY35511.1 - 2.1e-33 113.7 19.2 1e-07 31.5 0.1 8.2 5 2 3 8 8 8 5 TPR repeat TPR_8 PF13181.6 CBY35511.1 - 1.4e-25 87.3 31.9 3.2e-05 23.8 0.1 9.6 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 CBY35511.1 - 6.6e-23 81.1 0.1 0.00035 21.1 0.0 6.4 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBY35511.1 - 1.1e-19 70.5 13.1 8.7e-07 29.2 0.1 8.1 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY35511.1 - 1.7e-15 56.4 6.1 0.0025 18.5 0.1 8.3 7 2 1 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY35511.1 - 1.5e-14 53.2 16.6 0.12 12.8 0.1 9.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBY35511.1 - 1.2e-11 44.9 15.8 0.33 11.5 0.0 7.4 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBY35511.1 - 3.9e-10 39.0 6.8 4.8 7.4 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat MIT PF04212.18 CBY35511.1 - 6.7e-06 26.1 20.1 1.2 9.2 0.0 6.7 6 1 1 7 7 6 4 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CBY35511.1 - 7.1e-06 26.3 15.4 2.3 9.0 0.1 8.7 9 1 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY35511.1 - 0.00016 21.8 0.0 0.48 10.6 0.1 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBY35511.1 - 0.00061 19.6 20.6 0.89 9.2 0.4 5.6 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 CBY35511.1 - 0.00083 18.8 0.1 2.9 7.2 0.0 3.7 2 1 1 3 3 3 1 MalT-like TPR region ANAPC3 PF12895.7 CBY35511.1 - 0.00091 19.4 13.8 0.029 14.6 0.5 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CBY35511.1 - 0.0011 18.4 3.7 7.2 6.2 0.0 5.5 6 0 0 6 6 6 1 SHNi-TPR TPR_15 PF13429.6 CBY35511.1 - 0.0014 17.9 9.1 0.058 12.6 2.7 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBY35511.1 - 0.0022 17.8 11.1 24 5.0 0.2 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat ArnB_C PF18677.1 CBY35511.1 - 0.046 13.8 1.8 0.31 11.2 0.8 2.6 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain RTTN_N PF14726.6 CBY35511.1 - 0.13 13.1 0.4 25 5.7 0.0 2.7 3 0 0 3 3 2 0 Rotatin, an armadillo repeat protein, centriole functioning Fis1_TPR_C PF14853.6 CBY35511.1 - 0.64 10.1 14.6 49 4.1 0.0 6.6 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TCTP PF00838.17 CBY35511.1 - 0.79 10.0 11.3 0.66 10.3 4.9 3.0 1 1 1 2 2 2 0 Translationally controlled tumour protein TOM20_plant PF06552.12 CBY35511.1 - 1.2 8.9 14.0 14 5.3 0.1 5.0 3 2 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 SIKE PF05769.11 CBY35515.1 - 4.1e-11 43.1 2.7 1.3e-10 41.5 2.7 1.7 1 1 0 1 1 1 1 SIKE family Ribosomal_L25p PF01386.19 CBY35515.1 - 0.035 14.6 0.4 0.051 14.1 0.4 1.2 1 0 0 1 1 1 0 Ribosomal L25p family WXG100 PF06013.12 CBY35515.1 - 0.082 13.1 0.6 0.31 11.3 0.4 1.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DEAD_assoc PF08494.11 CBY35516.1 - 0.029 14.2 0.3 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 DEAD/H associated ADIP PF11559.8 CBY35516.1 - 0.083 13.0 23.2 0.23 11.6 11.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 CBY35516.1 - 0.088 12.7 2.8 2.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vps54_N PF10475.9 CBY35516.1 - 0.12 11.7 12.8 0.061 12.6 6.9 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 CBY35516.1 - 0.26 10.8 8.7 0.29 10.7 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO-like PF16789.5 CBY35516.1 - 0.62 10.1 22.5 0.069 13.2 10.7 2.2 1 1 1 2 2 2 0 YscO-like protein DUF724 PF05266.14 CBY35516.1 - 0.89 9.3 21.8 2.1 8.1 11.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 CBY35516.1 - 1.1 8.7 19.5 1.4 8.3 19.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 CBY35516.1 - 1.5 8.8 28.9 3.2 7.8 28.9 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Paralemmin PF03285.15 CBY35516.1 - 1.9 8.0 21.6 2.6 7.5 12.3 2.1 1 1 1 2 2 2 0 Paralemmin Fez1 PF06818.15 CBY35516.1 - 2 8.8 20.7 5.7 7.3 4.1 2.2 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 CBY35516.1 - 2.5 8.2 24.6 1.4 9.0 18.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 CBY35516.1 - 2.7 8.5 15.9 0.48 10.9 2.2 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF5339 PF17274.2 CBY35516.1 - 3.6 8.5 14.6 0.85 10.5 4.7 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5339) NPV_P10 PF05531.12 CBY35516.1 - 5.7 7.5 9.0 3 8.4 3.5 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBY35516.1 - 6.1 7.5 8.0 4.8 7.9 3.4 2.9 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 CBY35516.1 - 9.1 7.2 25.3 2.1 9.3 15.2 2.9 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 CBY35516.1 - 9.9 5.4 15.9 0.59 9.5 9.3 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M AKAP28 PF14469.6 CBY35517.1 - 1.3e-47 160.5 0.2 1.5e-47 160.3 0.2 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor GST_C PF00043.25 CBY35518.1 - 0.0016 18.6 0.6 0.012 15.8 0.0 2.6 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBY35518.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY35518.1 - 0.032 14.6 0.2 0.16 12.3 0.0 2.4 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain Mnd1 PF03962.15 CBY35518.1 - 0.068 13.5 0.6 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 Mnd1 HTH domain GST_N_4 PF17172.4 CBY35518.1 - 0.15 12.9 0.6 3.2 8.6 0.1 2.7 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Arf PF00025.21 CBY35519.1 - 1.3e-41 141.9 0.0 1.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY35519.1 - 2.4e-12 47.1 0.0 3.3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY35519.1 - 9.2e-12 44.9 0.0 1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY35519.1 - 2.1e-11 43.6 0.3 1.4e-06 27.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBY35519.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY35519.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY35519.1 - 4.6e-05 23.5 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY35519.1 - 0.02 15.1 0.0 0.07 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CBY35519.1 - 0.13 11.8 0.0 2.9 7.4 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain UCH PF00443.29 CBY35520.1 - 3.6e-50 170.8 0.0 5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY35520.1 - 9.3e-15 55.0 0.2 3.6e-12 46.5 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBY35520.1 - 0.0015 18.1 0.2 0.57 9.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase OTU PF02338.19 CBY35521.1 - 1e-09 38.9 0.0 2.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Podovirus_Gp16 PF05894.12 CBY35521.1 - 0.055 12.9 0.1 0.69 9.3 0.0 2.0 2 0 0 2 2 2 0 Podovirus DNA encapsidation protein (Gp16) Zn-ribbon_8 PF09723.10 CBY35521.1 - 0.092 12.9 3.2 4.4 7.5 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Mu-like_Com PF10122.9 CBY35521.1 - 0.12 11.9 1.9 7.8 6.0 0.2 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com Lar_restr_allev PF14354.6 CBY35521.1 - 4.2 7.8 4.8 16 5.9 0.5 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar BSD PF03909.17 CBY35522.1 - 2.9e-08 33.6 0.3 2.9e-08 33.6 0.3 2.5 2 0 0 2 2 2 1 BSD domain DUF1451 PF07295.11 CBY35522.1 - 0.008 16.2 1.0 0.008 16.2 1.0 2.4 2 0 0 2 2 2 1 Zinc-ribbon containing domain RRM_1 PF00076.22 CBY35523.1 - 2.4e-17 62.5 0.0 3.8e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Serglycin PF04360.12 CBY35524.1 - 0.0083 16.1 0.3 0.011 15.7 0.3 1.3 1 0 0 1 1 1 1 Serglycin Phospholip_A2_1 PF00068.19 CBY35524.1 - 0.066 13.7 0.4 0.066 13.7 0.4 1.7 1 1 1 2 2 2 0 Phospholipase A2 WD40 PF00400.32 CBY35525.1 - 2.8e-06 27.9 4.9 0.038 14.9 0.1 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY35525.1 - 0.00081 18.4 0.2 0.05 12.5 0.0 3.1 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CBY35525.1 - 0.001 19.3 0.1 0.82 10.0 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CBY35525.1 - 0.017 13.7 0.0 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PhoPQ_related PF10142.9 CBY35526.1 - 3.6e-83 279.2 0.7 4.5e-83 278.9 0.7 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein zf-C3HC4_3 PF13920.6 CBY35527.1 - 0.00088 19.1 12.5 0.0072 16.2 6.8 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY35527.1 - 0.005 16.8 13.8 0.02 14.8 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain FlhC PF05280.11 CBY35527.1 - 0.059 13.1 0.5 0.088 12.5 0.5 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Prok-RING_4 PF14447.6 CBY35527.1 - 0.062 13.2 11.5 0.39 10.6 11.5 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY35527.1 - 0.074 12.9 9.5 1.6 8.7 9.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY35527.1 - 0.21 11.5 14.9 1.4 8.8 15.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY35527.1 - 0.5 10.4 10.7 1.1 9.4 10.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CBY35527.1 - 1.2 9.1 9.7 2.3 8.1 9.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CBY35527.1 - 2.4 8.5 14.7 17 5.8 15.0 2.1 1 1 1 2 2 2 0 Ring finger domain Zona_pellucida PF00100.23 CBY35529.1 - 1.8e-21 77.1 0.9 2.3e-21 76.8 0.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Orf78 PF06024.12 CBY35530.1 - 0.12 12.7 0.1 0.51 10.7 0.1 2.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF2189 PF09955.9 CBY35532.1 - 4.5 7.5 7.6 24 5.2 0.4 3.0 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2189) DUF384 PF04064.13 CBY35533.1 - 0.14 12.0 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) GnRH PF00446.17 CBY35534.1 - 0.0024 18.1 1.4 0.0045 17.2 1.4 1.4 1 0 0 1 1 1 1 Gonadotropin-releasing hormone RPE65 PF03055.15 CBY35536.1 - 9.3e-76 255.9 1.9 1.1e-75 255.7 1.9 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TauD PF02668.16 CBY35537.1 - 1.9e-30 106.6 0.0 6.1e-30 104.9 0.0 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CBY35537.1 - 8e-05 21.9 0.1 0.00015 21.0 0.0 1.4 2 0 0 2 2 2 1 CsiD Sulfatase PF00884.23 CBY35538.1 - 2.3e-20 73.2 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Reprolysin_2 PF13574.6 CBY35540.1 - 4.9e-24 85.3 0.5 9.6e-24 84.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY35540.1 - 1.3e-21 77.6 0.1 3.2e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Disintegrin PF00200.23 CBY35540.1 - 2.6e-11 44.2 22.3 2.6e-11 44.2 22.3 3.8 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 CBY35540.1 - 2.4e-09 37.8 0.4 1.5e-08 35.2 0.4 2.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY35540.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like P21-Arc PF04062.14 CBY35541.1 - 1.4e-62 210.9 0.0 1.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SipA PF09052.10 CBY35541.1 - 0.057 13.0 0.0 0.091 12.4 0.0 1.3 1 1 0 1 1 1 0 SipA N-terminal domain Docking PF08990.11 CBY35541.1 - 0.16 11.6 0.3 0.29 10.8 0.3 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking bZIP_1 PF00170.21 CBY35542.1 - 1.2e-18 66.9 12.3 1.7e-18 66.5 12.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY35542.1 - 2.1e-07 30.9 12.7 3e-07 30.4 12.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY35542.1 - 2.8e-05 24.6 6.5 4.1e-05 24.0 6.5 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 CBY35542.1 - 0.0034 16.8 0.5 0.0042 16.5 0.5 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Nnf1 PF03980.14 CBY35542.1 - 0.0099 16.3 0.7 0.014 15.7 0.7 1.3 1 0 0 1 1 1 1 Nnf1 TMCO5 PF14992.6 CBY35542.1 - 0.021 14.4 0.3 0.025 14.2 0.3 1.1 1 0 0 1 1 1 0 TMCO5 family HALZ PF02183.18 CBY35542.1 - 0.077 13.2 1.9 0.13 12.5 1.9 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF3128 PF11326.8 CBY35542.1 - 0.8 10.1 5.7 1.4 9.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) GLE1 PF07817.13 CBY35543.1 - 3.3e-27 95.3 0.0 2.7e-18 66.1 0.0 2.4 1 1 1 2 2 2 2 GLE1-like protein KptA_kDCL PF18176.1 CBY35543.1 - 0.0015 18.4 0.2 0.52 10.2 0.0 2.4 2 0 0 2 2 2 2 KptA in kinetoplastid DICER domain DUF4407 PF14362.6 CBY35543.1 - 2.3 7.5 16.7 2.3 7.5 15.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 CBY35543.1 - 3.8 7.9 10.4 2.2 8.7 7.7 1.9 2 0 0 2 2 2 0 YlqD protein MFS_1 PF07690.16 CBY35544.1 - 0.041 12.8 0.4 0.062 12.2 0.4 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily TPR_7 PF13176.6 CBY35545.1 - 4e-08 32.7 18.3 0.12 12.4 0.1 8.7 7 1 0 7 7 7 2 Tetratricopeptide repeat Nic96 PF04097.14 CBY35545.1 - 3.4e-07 29.1 7.6 0.16 10.4 0.8 4.7 3 2 2 5 5 5 3 Nup93/Nic96 Clathrin PF00637.20 CBY35545.1 - 4e-07 30.0 12.3 0.58 10.0 0.1 7.2 5 3 2 7 7 7 3 Region in Clathrin and VPS MIT PF04212.18 CBY35545.1 - 0.00037 20.5 15.1 0.44 10.7 0.4 5.3 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain Coatomer_WDAD PF04053.14 CBY35545.1 - 0.0033 16.5 5.0 0.083 11.9 1.3 3.1 2 1 0 2 2 2 2 Coatomer WD associated region TPR_2 PF07719.17 CBY35545.1 - 0.0084 16.2 32.4 1.2 9.4 1.7 10.0 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY35545.1 - 0.013 15.8 19.2 9.8 6.5 0.0 8.0 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY35545.1 - 0.092 12.6 18.3 8.5 6.4 1.3 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat PuR_N PF09182.10 CBY35545.1 - 0.14 12.1 0.2 2.5 8.1 0.0 2.8 1 1 1 2 2 2 0 Bacterial purine repressor, N-terminal TPR_14 PF13428.6 CBY35545.1 - 0.71 10.9 18.0 30 5.8 0.0 8.5 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY35545.1 - 3.1 8.2 12.1 11 6.5 1.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 CBY35547.1 - 8.2e-07 29.6 0.8 0.076 13.9 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35547.1 - 6.3e-06 26.4 0.0 0.17 12.2 0.0 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 CBY35547.1 - 0.016 14.3 0.1 0.063 12.3 0.0 1.9 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 CBY35547.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Utp8 PF10395.9 CBY35547.1 - 0.05 12.1 0.0 4.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Utp8 family Flp_N PF03930.14 CBY35550.1 - 0.0059 16.6 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus DUF2787 PF10980.8 CBY35550.1 - 0.09 13.0 0.2 0.28 11.4 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2787) Pkinase_Tyr PF07714.17 CBY35551.1 - 3.6e-50 170.7 0.0 5.1e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35551.1 - 5.6e-50 170.2 0.0 8.1e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY35551.1 - 6.3e-05 21.9 0.4 0.00016 20.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CBY35551.1 - 0.00012 21.8 0.6 0.12 12.0 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CBY35551.1 - 0.0023 17.6 0.2 0.016 14.8 0.2 2.2 1 1 0 1 1 1 1 RIO1 family zf-C4H2 PF10146.9 CBY35551.1 - 0.17 12.2 3.8 0.63 10.3 3.8 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein bZIP_2 PF07716.15 CBY35552.1 - 0.00014 21.8 11.3 0.00014 21.8 11.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY35552.1 - 0.00025 21.1 10.1 0.00025 21.1 10.1 2.3 1 1 1 2 2 2 1 bZIP transcription factor DUF3450 PF11932.8 CBY35552.1 - 0.068 12.5 6.6 0.11 11.8 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 CBY35552.1 - 0.15 12.6 10.8 0.18 12.4 9.8 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF883 PF05957.13 CBY35552.1 - 0.3 11.7 2.6 0.76 10.4 2.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 CBY35552.1 - 1.6 9.4 5.4 3.5 8.3 5.0 1.9 1 1 0 1 1 1 0 Initiation control protein YabA CASP_C PF08172.12 CBY35552.1 - 6.4 6.0 15.3 0.33 10.3 2.5 2.2 1 1 1 2 2 2 0 CASP C terminal bZIP_1 PF00170.21 CBY35553.1 - 8.7e-08 32.2 7.5 8.7e-08 32.2 7.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY35553.1 - 7.1e-07 29.2 10.7 7.1e-07 29.2 10.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper HTH_ABP1_N PF18107.1 CBY35553.1 - 0.028 14.1 0.7 0.067 12.9 0.7 1.6 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain YabA PF06156.13 CBY35553.1 - 2.7 8.7 5.1 4.9 7.8 4.7 1.7 1 1 1 2 2 2 0 Initiation control protein YabA SH3_1 PF00018.28 CBY35554.1 - 0.0058 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY35554.1 - 0.13 12.1 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain DUF1681 PF07933.14 CBY35555.1 - 4.2e-53 179.0 0.0 5.4e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.25 CBY35556.1 - 3.5e-67 226.6 0.0 4.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35556.1 - 1.1e-33 116.6 0.0 1.9e-33 115.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY35556.1 - 9.9e-06 25.6 0.4 7.8e-05 22.7 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY35556.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY35556.1 - 0.0019 17.6 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY35556.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 3 0 0 3 3 3 0 Kinase-like Apt1 PF10351.9 CBY35556.1 - 0.13 11.1 7.6 0.17 10.7 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyco_hydro_63 PF03200.16 CBY35557.1 - 3.4e-190 633.0 0.3 4.4e-190 632.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CBY35557.1 - 3.1e-30 106.0 3.3 5.9e-30 105.1 3.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CBY35557.1 - 0.0031 16.5 0.0 0.0063 15.5 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF2914 PF11141.8 CBY35557.1 - 0.14 11.9 0.6 0.43 10.4 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) TGF_beta PF00019.20 CBY35558.1 - 1.2e-31 109.7 1.3 1.2e-31 109.7 1.3 1.9 2 0 0 2 2 2 1 Transforming growth factor beta like domain Homeodomain PF00046.29 CBY35561.1 - 1.6e-21 75.9 5.1 3.8e-21 74.7 5.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY35561.1 - 0.0086 16.0 0.1 0.032 14.1 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Chordopox_A13L PF05961.11 CBY35561.1 - 0.39 11.0 1.6 0.55 10.5 0.3 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein BAR PF03114.18 CBY35562.1 - 0.013 15.2 3.1 0.015 15.0 3.1 1.1 1 0 0 1 1 1 0 BAR domain DUF4106 PF13388.6 CBY35562.1 - 0.044 13.0 1.5 0.046 13.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF16 PF01519.16 CBY35562.1 - 0.045 14.2 3.8 0.062 13.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Herpes_UL36 PF03586.13 CBY35562.1 - 0.048 13.0 0.2 0.059 12.7 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein HMMR_C PF15908.5 CBY35562.1 - 0.1 12.8 3.4 0.14 12.4 3.2 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF1912 PF08930.10 CBY35562.1 - 0.19 11.9 2.5 0.19 11.9 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1912) BRE1 PF08647.11 CBY35562.1 - 0.27 11.3 5.8 1 9.5 5.5 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DZF PF07528.14 CBY35563.1 - 9.6e-37 126.9 0.0 6.5e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 DZF domain HBS1_N PF08938.10 CBY35563.1 - 0.11 12.8 0.2 1 9.7 0.1 2.2 2 0 0 2 2 2 0 HBS1 N-terminus PAP_assoc PF03828.19 CBY35564.1 - 1.1e-07 32.0 0.2 2.7e-07 30.7 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY35564.1 - 1.1e-05 25.6 0.0 5.2e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY35564.1 - 0.0081 16.2 0.1 0.051 13.7 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Arylsulfotran_N PF17425.2 CBY35564.1 - 0.091 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain LMBR1 PF04791.16 CBY35566.1 - 3 6.7 4.4 4.9 6.0 4.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 CBY35566.1 - 4.7 5.9 9.3 0.14 10.9 3.2 1.5 2 0 0 2 2 2 0 Presenilin SH3_1 PF00018.28 CBY35567.1 - 9.2e-09 34.8 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY35567.1 - 1.4e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY35567.1 - 0.00024 20.7 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CG-1 PF03859.16 CBY35567.1 - 0.016 15.0 0.2 0.042 13.7 0.2 1.6 1 0 0 1 1 1 0 CG-1 domain SH3_3 PF08239.11 CBY35567.1 - 0.067 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4660 PF15559.6 CBY35567.1 - 0.079 13.3 2.6 0.11 12.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4660) Phospholip_A2_1 PF00068.19 CBY35568.1 - 1.5e-15 57.6 6.2 2.1e-15 57.1 6.2 1.2 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.18 CBY35568.1 - 6.7 7.1 11.3 2.1e+02 2.3 11.4 2.3 1 1 0 1 1 1 0 EB module IP_trans PF02121.18 CBY35569.1 - 8.2e-41 140.2 1.4 1e-40 139.9 1.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF577 PF04510.12 CBY35569.1 - 0.013 15.4 0.2 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF577) EF-hand_7 PF13499.6 CBY35570.1 - 2.3e-10 40.8 0.8 1.8e-05 25.1 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY35570.1 - 1.4e-08 34.0 0.5 4.3e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY35570.1 - 3.8e-08 32.3 0.6 1.2e-05 24.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY35570.1 - 4.5e-05 22.8 0.3 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CBY35570.1 - 0.0002 21.7 0.4 0.11 12.8 0.0 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY35570.1 - 0.00038 20.7 0.1 0.0088 16.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY35570.1 - 0.0024 17.7 0.7 0.012 15.4 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_14 PF17959.1 CBY35570.1 - 0.014 15.8 2.7 0.016 15.5 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain RST PF12174.8 CBY35570.1 - 0.016 15.1 0.4 0.14 12.1 0.1 2.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain VGCC_beta4Aa_N PF12052.8 CBY35571.1 - 0.039 14.1 0.5 0.039 14.1 0.5 3.6 5 0 0 5 5 5 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Spc7 PF08317.11 CBY35571.1 - 1.7 7.4 77.9 0.16 10.8 17.7 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein DUF948 PF06103.11 CBY35571.1 - 4.3 7.7 14.0 9 6.6 4.4 5.0 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) PLAC8 PF04749.17 CBY35572.1 - 4.9e-07 30.7 9.1 6.3e-07 30.3 9.1 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBY35574.1 - 1e-17 64.9 15.1 2e-17 64.0 15.1 1.4 1 1 0 1 1 1 1 PLAC8 family 7tm_1 PF00001.21 CBY35576.1 - 3.3e-32 111.9 8.2 1.8e-31 109.5 8.2 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) LapA_dom PF06305.11 CBY35576.1 - 0.0024 17.6 0.1 0.0024 17.6 0.1 2.6 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain 7tm_4 PF13853.6 CBY35576.1 - 0.0024 17.6 6.4 0.0072 16.1 6.3 1.9 1 1 0 1 1 1 1 Olfactory receptor DHHC PF01529.20 CBY35576.1 - 7.3 6.7 16.8 1.1 9.4 2.3 3.3 3 1 0 3 3 3 0 DHHC palmitoyltransferase STOP PF05217.12 CBY35577.1 - 0.024 14.9 0.1 0.024 14.9 0.1 2.3 2 0 0 2 2 2 0 STOP protein EF-hand_1 PF00036.32 CBY35579.1 - 2.4e-08 32.9 1.3 0.00035 19.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY35579.1 - 1e-06 27.9 1.0 0.00054 19.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY35579.1 - 1.1e-06 28.9 3.2 0.022 15.2 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY35579.1 - 3.4e-06 26.5 3.8 0.02 14.8 0.2 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBY35579.1 - 0.024 14.5 0.9 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF4698 PF15769.5 CBY35580.1 - 0.036 13.1 0.2 0.056 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) TubC_N PF18563.1 CBY35580.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 TubC N-terminal docking domain Calx-beta PF03160.14 CBY35581.1 - 2.7e-83 274.5 16.1 3.7e-18 65.5 0.1 14.1 15 1 0 15 15 15 11 Calx-beta domain Integrin_beta PF00362.18 CBY35581.1 - 8e-76 255.0 0.0 1.7e-75 253.9 0.0 1.6 1 0 0 1 1 1 1 Integrin beta chain VWA domain I-EGF_1 PF18372.1 CBY35581.1 - 4.3e-07 29.9 2.5 4.3e-07 29.9 2.5 4.7 5 1 0 5 5 5 2 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 CBY35581.1 - 7.6e-06 26.2 67.6 0.00033 21.0 12.8 5.1 4 1 0 4 4 4 4 EGF-like domain DUF4843 PF16132.5 CBY35581.1 - 2.9e-05 23.7 0.2 5.1 6.6 0.1 5.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4843) Scramblase PF03803.15 CBY35582.1 - 8.5e-05 21.9 0.0 9.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Scramblase GHMP_kinases_N PF00288.26 CBY35583.1 - 0.0053 17.0 2.0 0.41 10.9 0.3 2.5 2 0 0 2 2 2 2 GHMP kinases N terminal domain DUF92 PF01940.16 CBY35583.1 - 0.023 14.1 0.7 0.031 13.7 0.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 Fez1 PF06818.15 CBY35584.1 - 0.0042 17.6 8.3 0.0048 17.4 8.3 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 CBY35584.1 - 0.0086 15.0 10.6 0.01 14.7 10.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein MIP-T3_C PF17749.1 CBY35584.1 - 0.024 14.6 11.8 0.024 14.6 11.8 1.7 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region MPS2 PF17060.5 CBY35584.1 - 0.043 13.1 6.0 0.051 12.8 6.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 HMMR_N PF15905.5 CBY35584.1 - 0.044 13.3 12.2 0.055 12.9 12.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HrpB7 PF09486.10 CBY35584.1 - 0.053 13.9 1.6 0.084 13.3 1.6 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) UPF0242 PF06785.11 CBY35584.1 - 0.063 13.4 11.3 0.038 14.1 9.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY35584.1 - 0.13 12.3 4.6 0.18 11.9 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 CBY35584.1 - 0.15 12.8 3.8 0.35 11.6 3.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 CBY35584.1 - 0.41 10.2 3.5 0.41 10.2 3.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LCIB_C_CA PF18599.1 CBY35584.1 - 0.45 9.8 2.5 0.54 9.5 2.5 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF745 PF05335.13 CBY35584.1 - 0.63 9.7 5.3 1.1 9.0 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) OmpH PF03938.14 CBY35584.1 - 1.1 9.5 14.5 1.7 9.0 14.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 CBY35584.1 - 2.6 5.9 8.1 2.7 5.8 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.19 CBY35584.1 - 4.5 6.9 13.9 8.7 6.0 12.8 1.7 1 1 1 2 2 2 0 GrpE Scramblase PF03803.15 CBY35585.1 - 3.8e-23 81.9 0.0 5.7e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Scramblase BAF PF02961.14 CBY35585.1 - 1.7e-20 73.2 1.0 4.1e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 Barrier to autointegration factor Auto_anti-p27 PF06677.12 CBY35586.1 - 6.2e-16 58.3 2.7 1e-15 57.6 2.7 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_4 PF15227.6 CBY35586.1 - 0.0014 18.8 0.3 0.0026 17.9 0.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PPTA PF01239.22 CBY35587.1 - 5.7e-29 99.0 11.5 1.9e-08 33.7 0.1 5.2 4 1 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat ZapC PF07126.12 CBY35587.1 - 0.0094 15.5 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Cell-division protein ZapC HILPDA PF15220.6 CBY35587.1 - 0.019 15.1 0.0 6.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated FBA PF04300.13 CBY35587.1 - 0.063 13.0 0.3 0.12 12.0 0.2 1.5 1 1 0 1 1 1 0 F-box associated region MitoNEET_N PF10660.9 CBY35588.1 - 4.3e-11 42.7 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus zf-CDGSH PF09360.10 CBY35588.1 - 2.6e-09 37.1 0.2 4e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Pro_isomerase PF00160.21 CBY35589.1 - 1.9e-46 158.2 0.4 2.2e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S14 PF00253.21 CBY35590.1 - 0.052 13.3 0.1 0.2 11.5 0.1 2.0 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Myb_DNA-bind_7 PF15963.5 CBY35591.1 - 7.6e-18 64.2 1.0 7.6e-18 64.2 1.0 2.9 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBY35591.1 - 0.00012 22.2 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sedlin_N PF04628.13 CBY35592.1 - 9.8e-15 54.8 0.3 1e-14 54.8 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CBY35592.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 Sybindin-like family Nup35_RRM PF05172.13 CBY35592.1 - 0.091 12.7 0.0 0.88 9.6 0.0 2.0 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif SPA PF08616.10 CBY35593.1 - 2e-09 37.4 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.21 CBY35593.1 - 1.5e-07 31.6 0.6 3.4e-05 23.9 0.2 3.0 2 1 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 CBY35593.1 - 0.0033 16.2 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Transport protein Avl9 Tmemb_9 PF05434.11 CBY35594.1 - 0.054 13.4 0.1 0.067 13.1 0.1 1.1 1 0 0 1 1 1 0 TMEM9 Pet20 PF08692.10 CBY35596.1 - 2.3 8.9 7.4 8.2 7.2 6.5 2.2 1 1 0 1 1 1 0 Mitochondrial protein Pet20 Protocadherin PF08374.11 CBY35598.1 - 0.05 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Peptidase_M56 PF05569.11 CBY35598.1 - 0.063 12.5 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Prok-RING_4 PF14447.6 CBY35598.1 - 0.2 11.5 8.7 0.88 9.5 8.7 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SseC PF04888.12 CBY35598.1 - 3 7.4 5.5 4.5 6.8 5.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PWWP PF00855.17 CBY35599.1 - 8.8e-14 51.7 0.4 3.1e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 PWWP domain PWWP PF00855.17 CBY35600.1 - 1.2e-11 44.8 0.3 1.9e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 PWWP domain Kelch_5 PF13854.6 CBY35602.1 - 1.5e-17 63.2 7.4 0.00024 21.0 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CBY35602.1 - 1.8e-12 47.1 3.5 0.003 17.5 0.0 6.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY35602.1 - 2.9e-08 33.7 1.9 5.8 7.4 0.1 6.7 6 0 0 6 6 6 2 Kelch motif PSI PF01437.25 CBY35602.1 - 4.1e-08 33.6 32.5 4.3e-06 27.2 9.5 7.0 6 1 0 6 6 6 2 Plexin repeat Kelch_2 PF07646.15 CBY35602.1 - 6.3e-08 32.3 8.4 0.069 13.2 0.0 6.4 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.6 CBY35602.1 - 0.00018 21.7 4.3 2.9 8.3 0.1 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY35602.1 - 0.0005 19.6 0.6 3.5 7.3 0.0 5.5 6 0 0 6 6 6 1 Kelch motif Laminin_EGF PF00053.24 CBY35602.1 - 0.0011 19.1 43.3 0.0019 18.3 16.7 5.2 5 1 1 6 6 6 2 Laminin EGF domain Nup35_RRM_2 PF14605.6 CBY35603.1 - 6e-12 45.4 0.1 5.6e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 CBY35603.1 - 4.3e-09 36.6 1.8 6.6e-09 36.0 0.2 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 CBY35603.1 - 1.3e-07 31.3 0.2 0.00013 21.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CBY35603.1 - 5.1e-05 23.1 3.0 0.0001 22.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY35603.1 - 0.0019 18.2 2.3 0.0033 17.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM PF05172.13 CBY35603.1 - 0.0031 17.5 0.3 0.11 12.5 0.0 2.9 2 2 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY35603.1 - 0.0083 16.1 4.2 0.55 10.3 0.4 3.4 3 0 0 3 3 3 1 RNA binding motif RL PF17797.1 CBY35603.1 - 0.011 15.7 0.1 12 6.0 0.0 3.1 3 0 0 3 3 3 0 RL domain DUF1866 PF08952.11 CBY35603.1 - 0.013 15.3 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_5 PF13893.6 CBY35603.1 - 0.02 14.5 0.0 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 CBY35603.1 - 0.53 10.8 3.0 2.1 8.9 0.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger WD40 PF00400.32 CBY35604.1 - 6.5e-07 29.9 0.2 0.0016 19.2 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35604.1 - 0.0015 18.8 0.0 0.01 16.1 0.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BRK PF07533.16 CBY35604.1 - 0.027 14.1 0.2 0.092 12.4 0.1 2.0 2 0 0 2 2 2 0 BRK domain RTP1_C1 PF10363.9 CBY35605.1 - 4.1e-11 43.1 0.1 4.1e-11 43.1 0.1 2.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HABP4_PAI-RBP1 PF04774.15 CBY35605.1 - 0.12 13.2 3.2 0.11 13.3 1.8 1.6 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Skp1_POZ PF03931.15 CBY35606.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Arf PF00025.21 CBY35607.1 - 1.8e-07 30.8 0.1 2.3e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY35607.1 - 9.1e-06 25.9 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBY35607.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY35607.1 - 2.5e-05 24.3 0.1 3.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CBY35607.1 - 0.0014 18.1 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 CBY35607.1 - 0.0035 16.5 0.2 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DLIC PF05783.11 CBY35607.1 - 0.0036 16.2 0.2 0.0039 16.1 0.2 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 CBY35607.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Ras PF00071.22 CBY35607.1 - 0.058 13.0 0.0 0.094 12.3 0.0 1.4 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.27 CBY35607.1 - 0.058 13.9 0.0 0.079 13.5 0.0 1.3 1 1 0 1 1 1 0 ABC transporter CobU PF02283.16 CBY35607.1 - 0.062 12.9 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase G-alpha PF00503.20 CBY35607.1 - 0.067 12.3 2.3 0.077 12.1 0.2 1.9 2 1 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 CBY35607.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Complex1_51K PF01512.17 CBY35608.1 - 5e-49 166.1 0.0 7.1e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBY35608.1 - 3.6e-26 91.1 0.1 1.5e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBY35608.1 - 6.8e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF780 PF05611.11 CBY35608.1 - 0.05 14.4 1.3 0.14 13.0 1.3 1.7 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF3568 PF12092.8 CBY35608.1 - 0.52 10.4 2.1 1 9.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) SpoU_methylase PF00588.19 CBY35609.1 - 8.7e-26 90.8 0.2 3e-25 89.1 0.1 2.0 2 0 0 2 2 2 1 SpoU rRNA Methylase family Surface_antigen PF11054.8 CBY35610.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen DUF4562 PF15123.6 CBY35610.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Actin PF00022.19 CBY35611.1 - 1.5e-99 333.4 0.0 1.5e-98 330.1 0.0 2.1 1 1 0 1 1 1 1 Actin UQ_con PF00179.26 CBY35612.1 - 1.3e-24 86.4 0.0 1.6e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HHV6-IE PF03753.13 CBY35612.1 - 0.15 9.5 0.0 0.18 9.3 0.0 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Fer2_3 PF13085.6 CBY35613.1 - 9.3e-32 109.3 0.1 1.5e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBY35613.1 - 0.0079 16.1 1.2 0.017 15.1 1.2 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_2 PF13923.6 CBY35614.1 - 9e-05 22.2 16.1 9e-05 22.2 16.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY35614.1 - 0.00096 19.0 11.2 0.0018 18.1 11.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY35614.1 - 0.0012 18.8 16.5 0.0031 17.4 16.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY35614.1 - 0.0029 17.6 9.2 0.0087 16.1 9.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY35614.1 - 0.0072 16.2 16.7 0.0072 16.2 16.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY35614.1 - 0.0092 16.1 12.0 0.033 14.4 12.0 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY35614.1 - 0.011 16.1 14.9 0.011 16.1 14.9 2.0 2 0 0 2 2 2 0 Ring finger domain ZapB PF06005.12 CBY35614.1 - 0.023 15.1 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CBY35614.1 - 0.028 15.0 6.0 0.034 14.8 6.0 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PCNP PF15473.6 CBY35614.1 - 0.08 13.7 0.2 0.11 13.2 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family zf-RING_4 PF14570.6 CBY35614.1 - 0.19 11.5 13.8 0.85 9.5 13.5 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 CBY35614.1 - 0.39 10.8 11.9 0.098 12.7 6.8 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.12 CBY35614.1 - 0.66 10.0 12.9 0.28 11.2 9.9 1.9 2 0 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 CBY35614.1 - 0.66 10.1 9.5 12 6.1 10.1 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger Pkinase PF00069.25 CBY35615.1 - 2.4e-63 214.0 0.0 3.3e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35615.1 - 6.3e-35 120.7 0.0 1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY35615.1 - 0.00078 18.8 0.1 0.18 11.1 0.0 2.5 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 CBY35615.1 - 0.0015 17.9 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY35615.1 - 0.0016 17.4 0.1 0.0016 17.4 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 CBY35615.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY35615.1 - 0.0028 17.6 0.1 0.92 9.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC1 PF03109.16 CBY35615.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Seadorna_VP7 PF07387.11 CBY35615.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 XRN_M PF17846.1 CBY35616.1 - 9.1e-144 479.7 0.1 1.5e-143 479.0 0.1 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CBY35616.1 - 4.2e-97 324.3 2.5 8.7e-97 323.3 0.0 2.3 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus HA2 PF04408.23 CBY35617.1 - 1.7e-17 63.7 0.0 3.6e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) R3H PF01424.22 CBY35617.1 - 8.7e-11 41.7 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain Helicase_C PF00271.31 CBY35617.1 - 3.1e-10 40.4 0.0 8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY35617.1 - 2.9e-07 30.4 0.1 6.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY35617.1 - 0.00055 20.2 0.4 0.0031 17.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY35617.1 - 0.0014 19.0 0.1 0.0044 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 CBY35617.1 - 0.0033 17.4 0.1 0.0092 16.0 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit OB_NTP_bind PF07717.16 CBY35617.1 - 0.0035 17.7 0.0 0.0069 16.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ATPase PF06745.13 CBY35617.1 - 0.0066 15.8 0.2 0.026 13.8 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_23 PF13476.6 CBY35617.1 - 0.0088 16.6 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBY35617.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CBY35617.1 - 0.044 13.7 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CBY35617.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBY35617.1 - 0.1 12.3 0.4 8.4 6.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 CBY35617.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 CBY35617.1 - 0.16 12.0 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBY35617.1 - 0.24 11.9 0.5 0.82 10.2 0.5 2.0 1 1 0 1 1 1 0 ABC transporter CBM_14 PF01607.24 CBY35618.1 - 0.00027 21.0 0.6 0.1 12.8 0.1 2.3 2 0 0 2 2 2 2 Chitin binding Peritrophin-A domain EF-hand_1 PF00036.32 CBY35619.1 - 0.087 12.4 0.8 19 5.1 0.0 2.9 2 0 0 2 2 2 0 EF hand LRR_8 PF13855.6 CBY35620.1 - 2.4e-50 168.1 51.3 1.8e-14 53.2 3.6 7.9 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CBY35620.1 - 5.2e-24 83.9 62.3 1.4e-08 34.9 1.1 9.3 4 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY35620.1 - 8e-20 71.1 22.4 8e-10 38.8 6.2 3.5 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY35620.1 - 6.1e-12 45.4 25.7 1.6e-06 27.7 4.0 4.9 1 1 3 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 CBY35620.1 - 1e-08 34.5 34.8 6.4 7.7 0.0 12.5 13 1 0 13 13 13 4 Leucine Rich Repeat DKNYY PF13644.6 CBY35620.1 - 0.00087 20.1 8.8 0.24 12.1 2.4 2.7 1 1 1 2 2 2 2 DKNYY family LRR_6 PF13516.6 CBY35620.1 - 0.0031 17.5 39.7 0.75 10.0 0.1 9.8 12 0 0 12 12 12 4 Leucine Rich repeat Gal_Lectin PF02140.18 CBY35622.1 - 4.6e-17 62.2 0.4 6.7e-17 61.7 0.4 1.2 1 0 0 1 1 1 1 Galactose binding lectin domain Tubulin PF00091.25 CBY35623.1 - 2.3e-66 223.7 0.0 3.6e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY35623.1 - 2.3e-49 166.7 0.0 4.2e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY35623.1 - 0.0033 17.1 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Glyco_hydro_35 PF01301.19 CBY35624.1 - 6.5e-91 305.2 1.4 8.6e-91 304.8 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY35624.1 - 1.2e-08 34.8 0.4 4.1e-08 33.0 0.4 1.8 1 1 0 1 1 1 1 Beta-galactosidase DUF3437 PF11919.8 CBY35624.1 - 0.4 10.6 1.8 6.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) CHGN PF05679.16 CBY35625.1 - 2.5e-72 244.4 1.9 1.1e-59 202.6 0.1 2.1 1 1 1 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY35625.1 - 1e-12 48.1 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY35625.1 - 1.9e-09 37.0 0.1 4.8e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Galactosyl_T PF01762.21 CBY35625.1 - 0.0001 22.2 0.0 0.15 11.9 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY35625.1 - 0.0032 17.0 0.5 0.0077 15.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2024 PF09630.10 CBY35625.1 - 0.3 11.0 3.9 0.54 10.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) GFO_IDH_MocA PF01408.22 CBY35626.1 - 4.3e-25 88.9 0.0 9.6e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CBY35626.1 - 4.5e-08 33.1 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CBY35626.1 - 2.7e-05 24.8 0.0 5.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBY35626.1 - 0.00092 19.8 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CBY35626.1 - 0.0035 17.8 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 CBY35626.1 - 0.0043 17.4 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CBY35626.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CBY35626.1 - 0.092 13.0 0.1 0.65 10.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Ribosomal_L28 PF00830.19 CBY35626.1 - 0.16 12.1 0.2 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L28 family Plasmodium_Vir PF05795.11 CBY35627.1 - 0.015 14.7 5.6 0.02 14.3 5.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 CBY35627.1 - 1.4 5.9 8.4 1.7 5.7 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 CBY35627.1 - 2.3 6.7 6.2 2.8 6.4 6.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF966 PF06136.13 CBY35627.1 - 7.1 6.3 8.9 8.5 6.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Radial_spoke_3 PF06098.11 CBY35632.1 - 6.6e-116 386.6 16.2 8.7e-116 386.2 16.2 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 LMBR1 PF04791.16 CBY35632.1 - 2.6 6.9 4.4 3.4 6.5 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4239 PF14023.6 CBY35632.1 - 3.4 7.3 4.5 14 5.4 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Macoilin PF09726.9 CBY35632.1 - 6.9 5.1 15.5 0.59 8.6 10.2 1.7 2 0 0 2 2 2 0 Macoilin family Zip PF02535.22 CBY35633.1 - 0.34 10.1 4.0 1.1 8.4 4.0 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter TMEM234 PF10639.9 CBY35634.1 - 1.6e-21 76.5 1.3 1.9e-21 76.2 1.3 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 SPOC PF07744.13 CBY35635.1 - 8.6e-20 71.2 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Spore_YhcN_YlaJ PF09580.10 CBY35635.1 - 0.0023 18.0 0.0 0.091 12.8 0.0 2.7 1 1 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cyt-b5 PF00173.28 CBY35637.1 - 2.8e-26 91.4 0.0 4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-HC2 PF13490.6 CBY35637.1 - 0.088 13.1 0.7 0.17 12.2 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger UreE_N PF02814.15 CBY35640.1 - 0.056 13.0 1.0 0.12 12.0 1.0 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Relaxase PF03432.14 CBY35640.1 - 7 6.2 11.8 0.48 10.0 6.7 1.6 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain WEMBL PF05701.11 CBY35641.1 - 0.0096 14.7 4.6 0.014 14.1 4.6 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ABC_tran_CTD PF16326.5 CBY35641.1 - 0.0098 16.1 0.7 0.54 10.6 0.2 2.5 2 0 0 2 2 2 1 ABC transporter C-terminal domain Fez1 PF06818.15 CBY35641.1 - 0.059 13.8 4.5 0.09 13.2 4.5 1.2 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.12 CBY35641.1 - 0.54 10.3 4.8 0.35 10.9 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CBY35641.1 - 1.2 9.4 5.2 1.9 8.8 0.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 CBY35641.1 - 2.3 8.8 8.2 0.66 10.5 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 CBY35641.1 - 3.4 7.2 5.8 8.4 5.9 1.0 2.3 1 1 1 2 2 2 0 fzo-like conserved region Prefoldin PF02996.17 CBY35641.1 - 5.5 6.9 11.2 4.2 7.3 0.8 3.4 2 1 1 4 4 4 0 Prefoldin subunit WD40 PF00400.32 CBY35642.1 - 2.4e-21 75.6 9.9 0.00013 22.7 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ATG16 PF08614.11 CBY35642.1 - 2.4e-18 67.1 18.9 3.7e-18 66.5 18.9 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 CBY35642.1 - 5.2e-09 36.3 0.2 0.11 12.8 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EzrA PF06160.12 CBY35642.1 - 0.00026 19.3 12.5 0.00035 18.9 12.5 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FlxA PF14282.6 CBY35642.1 - 0.00087 19.2 4.3 0.00087 19.2 4.3 2.0 2 0 0 2 2 2 1 FlxA-like protein Ge1_WD40 PF16529.5 CBY35642.1 - 0.0035 16.3 0.6 0.1 11.5 0.0 3.4 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY35642.1 - 0.012 14.3 8.6 0.38 9.3 0.6 3.7 3 2 2 5 5 5 0 Nucleoporin Nup120/160 APC_N_CC PF16689.5 CBY35642.1 - 0.043 13.9 0.5 0.043 13.9 0.5 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain WD40_like PF17005.5 CBY35642.1 - 0.05 12.9 0.0 0.55 9.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 CBY35642.1 - 0.13 12.3 0.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFA2_Winged_2 PF18121.1 CBY35642.1 - 0.16 11.7 0.9 1.3 8.8 0.5 2.8 3 1 0 3 3 3 0 TFA2 Winged helix domain 2 CENP-F_leu_zip PF10473.9 CBY35642.1 - 0.23 11.5 19.7 0.046 13.7 13.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 CBY35642.1 - 0.31 10.3 13.9 0.9 8.8 13.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Noelin-1 PF12308.8 CBY35642.1 - 0.32 11.0 1.9 0.94 9.5 1.9 1.8 1 0 0 1 1 1 0 Neurogenesis glycoprotein Fez1 PF06818.15 CBY35642.1 - 0.83 10.1 12.7 1.5 9.2 12.7 1.4 1 0 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 CBY35642.1 - 1.1 10.2 18.5 0.76 10.7 11.4 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 CBY35642.1 - 1.2 9.2 5.1 9.1 6.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 CBY35642.1 - 1.7 8.8 11.2 0.84 9.8 1.9 2.8 2 1 0 2 2 2 0 Swi5 DUF724 PF05266.14 CBY35642.1 - 3.8 7.3 12.0 16 5.2 11.9 2.1 2 1 1 3 3 2 0 Protein of unknown function (DUF724) ERM PF00769.19 CBY35642.1 - 5.2 6.8 22.3 0.98 9.2 9.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMPIT PF07851.13 CBY35642.1 - 10 5.3 10.7 2 7.6 0.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein Cyclin_N PF00134.23 CBY35643.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY35644.1 - 3.6e-06 27.0 0.2 1e-05 25.6 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CBY35644.1 - 0.00028 20.7 1.8 0.00092 19.0 1.3 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CBY35644.1 - 0.0021 18.4 0.2 0.0051 17.2 0.2 1.7 1 1 0 1 1 1 1 Cyclin C-terminal domain PRP38_assoc PF12871.7 CBY35644.1 - 0.023 15.3 49.2 0.023 15.3 49.2 2.2 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GREB1 PF15782.5 CBY35644.1 - 1.7 5.6 6.9 2.2 5.3 6.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RSRP PF17069.5 CBY35644.1 - 2.8 7.4 44.0 3.8 7.0 44.0 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RasGEF PF00617.19 CBY35645.1 - 7.4e-44 150.0 0.4 1.3e-42 146.0 0.1 2.0 1 1 1 2 2 2 2 RasGEF domain PH PF00169.29 CBY35646.1 - 1.9e-05 25.1 0.2 2.6e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 PH domain Astacin PF01400.24 CBY35647.1 - 2.5e-22 79.4 0.3 4e-21 75.5 0.2 2.5 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY35647.1 - 1.5e-08 34.7 17.5 2.8e-07 30.6 4.7 12.1 11 1 0 11 11 11 4 Calcium-binding EGF domain cEGF PF12662.7 CBY35647.1 - 7.7e-05 22.5 0.7 7.7e-05 22.5 0.7 9.3 8 1 0 8 8 8 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY35647.1 - 0.00062 19.9 16.1 0.00081 19.5 5.4 13.1 14 0 0 14 14 14 3 EGF domain MBOAT PF03062.19 CBY35648.1 - 3.7e-11 43.0 14.9 1.1e-10 41.4 14.5 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF2070 PF09843.9 CBY35648.1 - 3.1 6.0 9.0 0.033 12.5 1.6 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3624 PF12292.8 CBY35649.1 - 0.017 15.5 0.5 0.036 14.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) TMEM208_SND2 PF05620.11 CBY35649.1 - 0.025 14.3 0.0 0.025 14.3 0.0 2.2 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 TIL PF01826.17 CBY35650.1 - 1e-17 64.1 132.7 7.8e-10 38.9 19.5 7.7 5 3 2 7 7 7 4 Trypsin Inhibitor like cysteine rich domain zf-C4 PF00105.18 CBY35651.1 - 7.7e-27 93.6 13.0 1.2e-26 93.0 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY35651.1 - 3.9 7.9 11.9 0.32 11.3 2.7 2.6 2 1 0 2 2 2 0 C1 domain Hormone_recep PF00104.30 CBY35652.1 - 0.00047 19.8 0.2 0.0038 16.8 0.1 2.3 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor SNN_linker PF09050.10 CBY35652.1 - 0.81 9.5 2.2 1.6 8.6 2.2 1.5 1 0 0 1 1 1 0 Stannin unstructured linker LRR_6 PF13516.6 CBY35654.1 - 2.6e-05 23.9 1.6 2.1 8.6 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 CBY35654.1 - 0.015 15.1 7.2 2.6 7.9 0.7 4.6 3 2 1 4 4 4 0 Leucine rich repeat DUF2960 PF11173.8 CBY35654.1 - 0.038 14.4 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) LRR_4 PF12799.7 CBY35654.1 - 0.069 13.6 10.9 0.39 11.2 0.9 4.5 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY35654.1 - 7.9 7.5 15.1 5.1 8.0 0.1 5.2 4 2 0 4 4 4 0 Leucine Rich Repeat ADIP PF11559.8 CBY35655.1 - 0.011 15.9 6.3 0.011 15.9 6.3 3.3 2 2 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF745 PF05335.13 CBY35655.1 - 0.019 14.7 14.4 0.032 14.0 6.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF745) OmpH PF03938.14 CBY35655.1 - 0.026 14.9 15.4 0.2 12.0 1.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Holin_BhlA PF10960.8 CBY35655.1 - 0.07 13.1 1.9 0.24 11.4 1.9 2.0 1 0 0 1 1 1 0 BhlA holin family Atg14 PF10186.9 CBY35655.1 - 0.43 9.6 23.8 1.6 7.8 5.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CALCOCO1 PF07888.11 CBY35655.1 - 0.5 9.2 27.8 0.63 8.8 27.8 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.6 CBY35655.1 - 0.63 9.7 25.5 1.1 9.0 10.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 CBY35655.1 - 0.85 10.0 15.0 1.9 8.9 2.5 2.8 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CorA PF01544.18 CBY35655.1 - 1.3 8.2 11.5 4.7 6.4 10.2 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PRKG1_interact PF15898.5 CBY35655.1 - 3.8 8.5 24.0 3.6 8.5 5.6 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain RelA_SpoT PF04607.17 CBY35655.1 - 5 7.4 10.0 1.4 9.2 0.5 2.4 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins ABC_tran_CTD PF16326.5 CBY35655.1 - 8.1 6.8 15.3 2.8 8.3 6.4 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain HIP1_clath_bdg PF16515.5 CBY35655.1 - 9.6 6.9 24.2 1.5 9.5 6.7 3.5 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pkinase PF00069.25 CBY35658.1 - 8.3e-15 54.9 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35658.1 - 2.5e-11 43.4 0.0 5.7e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase NUC173 PF08161.12 CBY35658.1 - 0.031 13.9 0.2 0.073 12.7 0.2 1.6 1 0 0 1 1 1 0 NUC173 domain Rcd1 PF04078.13 CBY35658.1 - 0.096 12.0 0.1 0.27 10.5 0.1 1.7 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like RTBV_P46 PF06216.11 CBY35659.1 - 0.0056 15.6 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein DnaJ PF00226.31 CBY35660.1 - 8.4e-05 22.6 0.1 0.0051 16.9 0.1 2.4 1 1 0 1 1 1 1 DnaJ domain Tubulin PF00091.25 CBY35661.1 - 2.9e-68 230.0 0.0 3.6e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY35661.1 - 3.1e-42 143.7 0.0 5.3e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY35661.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain CAP PF00188.26 CBY35663.1 - 0.00013 22.8 0.0 0.0019 19.0 0.0 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3107 PF11305.8 CBY35663.1 - 0.00099 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) Triabin PF03973.13 CBY35664.1 - 0.074 12.9 1.8 0.44 10.4 0.1 2.1 1 1 1 2 2 2 0 Triabin Ephrin_rec_like PF07699.13 CBY35665.1 - 3.1e-09 36.5 10.6 3.3e-06 26.8 5.9 3.3 1 1 1 2 2 2 2 Putative ephrin-receptor like TSP_1 PF00090.19 CBY35665.1 - 0.00097 19.3 16.0 0.00097 19.3 16.0 4.5 4 1 0 4 4 4 1 Thrombospondin type 1 domain Peptidase_S49_N PF08496.10 CBY35665.1 - 2.6 8.1 4.2 0.96 9.5 1.4 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HEAT_2 PF13646.6 CBY35666.1 - 0.028 14.8 0.1 0.35 11.3 0.1 2.9 2 0 0 2 2 2 0 HEAT repeats HEAT_2 PF13646.6 CBY35667.1 - 0.0012 19.2 0.1 0.15 12.4 0.0 3.9 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CBY35667.1 - 0.0069 16.6 0.9 9.2 6.8 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat DUF3385 PF11865.8 CBY35667.1 - 0.073 13.0 0.5 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) ITI_HC_C PF06668.12 CBY35668.1 - 0.0006 19.5 0.0 0.0042 16.8 0.0 2.3 2 1 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Zona_pellucida PF00100.23 CBY35669.1 - 1.1e-34 120.4 3.0 1.9e-34 119.6 3.0 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Gla PF00594.20 CBY35669.1 - 2.3e-14 53.3 3.4 5.6e-14 52.1 3.4 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain EGF PF00008.27 CBY35669.1 - 5.7e-06 26.5 3.8 5.7e-06 26.5 3.8 2.1 2 0 0 2 2 2 1 EGF-like domain DUF2430 PF10353.9 CBY35669.1 - 0.054 13.9 0.9 0.41 11.1 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) TSP_1 PF00090.19 CBY35671.1 - 1.1e-19 70.3 167.0 3.7e-09 36.7 6.6 14.4 13 4 0 13 13 13 9 Thrombospondin type 1 domain DUF4294 PF14127.6 CBY35672.1 - 0.044 13.7 2.6 0.11 12.4 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) DUF2951 PF11166.8 CBY35672.1 - 1.3 9.2 7.6 0.26 11.5 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Phospholip_A2_1 PF00068.19 CBY35673.1 - 0.012 16.0 0.2 0.026 15.0 0.2 1.5 1 0 0 1 1 1 0 Phospholipase A2 SNF PF00209.18 CBY35674.1 - 1.1e-192 641.4 28.2 1.3e-192 641.2 28.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family EGF_CA PF07645.15 CBY35675.1 - 2.4e-78 258.1 302.1 1.8e-10 40.8 11.1 18.1 17 1 1 18 18 18 17 Calcium-binding EGF domain EGF_3 PF12947.7 CBY35675.1 - 1.3e-41 140.4 291.7 7.6e-09 35.6 10.1 18.3 17 0 0 17 17 17 17 EGF domain cEGF PF12662.7 CBY35675.1 - 2.4e-32 110.5 179.1 3.8e-05 23.5 3.0 19.3 18 0 0 18 18 18 14 Complement Clr-like EGF-like EGF PF00008.27 CBY35675.1 - 7.3e-10 39.0 243.3 0.00056 20.2 6.2 19.1 17 2 0 17 17 17 13 EGF-like domain hEGF PF12661.7 CBY35675.1 - 6.9e-05 23.3 198.3 0.015 15.9 1.0 21.1 19 1 0 19 19 19 12 Human growth factor-like EGF Peptidase_C50 PF03568.17 CBY35676.1 - 4.6e-08 32.6 0.4 2e-07 30.5 0.4 2.1 1 0 0 1 1 1 1 Peptidase family C50 DUF4611 PF15387.6 CBY35676.1 - 0.23 11.7 10.5 1.3 9.3 10.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cob_adeno_trans PF01923.18 CBY35676.1 - 1.1 9.4 4.8 1 9.5 0.3 3.2 2 0 0 2 2 2 0 Cobalamin adenosyltransferase RXT2_N PF08595.11 CBY35676.1 - 9.8 6.2 15.8 1.1 9.2 8.2 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal LRR_8 PF13855.6 CBY35677.1 - 1.5e-10 40.7 5.4 1.3e-05 24.9 0.1 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY35677.1 - 1.5e-07 31.6 12.3 0.00015 22.1 0.8 4.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY35677.1 - 0.56 11.0 11.5 19 6.3 0.1 4.7 3 2 0 3 3 3 0 Leucine Rich Repeat Folliculin PF11704.8 CBY35677.1 - 9.5 6.1 11.0 1.9e+02 1.8 11.0 2.1 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Band_7 PF01145.25 CBY35678.1 - 1.1e-28 100.5 1.7 1.4e-28 100.1 1.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY35678.1 - 0.047 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family PH PF00169.29 CBY35679.1 - 1.9e-07 31.5 2.5 1.7e-05 25.3 2.2 3.4 3 1 0 3 3 3 1 PH domain PH_11 PF15413.6 CBY35679.1 - 0.00014 22.2 4.4 0.011 16.2 0.4 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain Abhydrolase_1 PF00561.20 CBY35679.1 - 0.05 13.2 0.3 0.084 12.5 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Regulator_TrmB PF11495.8 CBY35679.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB PH_8 PF15409.6 CBY35679.1 - 7.9 6.8 11.1 0.87 9.9 0.7 3.7 4 0 0 4 4 4 0 Pleckstrin homology domain EF-hand_1 PF00036.32 CBY35680.1 - 4.3e-17 60.3 13.1 0.0002 20.7 0.0 6.5 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 CBY35680.1 - 1.3e-16 59.1 11.8 0.0031 17.3 0.0 6.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_7 PF13499.6 CBY35680.1 - 1e-14 54.7 20.5 8.7e-07 29.3 0.4 5.0 2 2 5 7 7 7 6 EF-hand domain pair EF-hand_5 PF13202.6 CBY35680.1 - 8.7e-13 47.1 19.6 0.0001 21.6 0.3 6.8 7 0 0 7 7 7 4 EF hand SPARC_Ca_bdg PF10591.9 CBY35680.1 - 8.2e-05 22.9 15.8 0.14 12.5 1.0 3.9 1 1 3 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY35680.1 - 0.0012 18.6 1.7 0.56 10.1 0.1 4.2 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY35680.1 - 0.011 15.5 16.1 1.4 8.9 0.0 5.4 6 1 0 6 6 6 0 EF-hand domain pair DUF1707 PF08044.11 CBY35680.1 - 0.071 13.2 0.3 9.1 6.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) EF-hand_4 PF12763.7 CBY35680.1 - 7.2 6.6 14.4 3.7 7.6 2.7 3.9 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand zf-C2H2 PF00096.26 CBY35682.1 - 4.3e-15 55.2 19.7 6.4e-05 23.2 2.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY35682.1 - 2.5e-10 40.3 10.2 5.5e-07 29.7 1.9 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY35682.1 - 1.6e-08 34.7 18.6 0.0013 19.4 2.2 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY35682.1 - 0.00047 20.7 8.4 0.036 14.7 0.8 2.8 2 1 1 3 3 3 2 FOXP coiled-coil domain Ogr_Delta PF04606.12 CBY35682.1 - 0.0054 16.7 1.2 0.072 13.1 0.3 2.6 1 1 1 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 CBY35682.1 - 0.079 13.3 3.9 1.1 9.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY35682.1 - 0.083 12.9 1.1 0.083 12.9 1.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY35682.1 - 1.9 8.2 9.6 0.34 10.6 0.9 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY35682.1 - 2.2 8.8 6.2 0.99 9.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Calsarcin PF05556.11 CBY35683.1 - 0.0046 16.5 0.1 0.0097 15.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-binding protein (Calsarcin) TRAM_LAG1_CLN8 PF03798.16 CBY35684.1 - 6.3e-15 55.4 17.8 8.5e-15 55.0 17.8 1.2 1 0 0 1 1 1 1 TLC domain Motile_Sperm PF00635.26 CBY35685.1 - 2.7e-27 94.8 0.4 5.6e-27 93.8 0.4 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Frizzled PF01534.17 CBY35686.1 - 1.8e-27 96.3 4.5 2.2e-27 96.0 4.5 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 CBY35687.1 - 7.7e-21 74.8 0.3 9.5e-21 74.5 0.3 1.1 1 0 0 1 1 1 1 Fz domain zf-C2H2 PF00096.26 CBY35688.1 - 0.012 16.0 2.8 0.022 15.2 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type PBP_sp32 PF07222.12 CBY35688.1 - 2.3 7.6 8.3 4.7 6.6 8.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cation_efflux PF01545.21 CBY35690.1 - 4.5e-47 160.4 7.5 5.4e-47 160.1 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family DUF5134 PF17197.4 CBY35690.1 - 0.027 14.4 0.0 0.069 13.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Amidase_2 PF01510.25 CBY35692.1 - 4.2e-15 56.3 0.3 8.2e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Pkinase PF00069.25 CBY35693.1 - 3.6e-60 203.5 0.0 9e-60 202.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY35693.1 - 2.6e-34 117.1 0.1 1e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY35693.1 - 2.1e-26 92.8 0.0 5.7e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY35693.1 - 0.0012 18.3 0.1 0.053 12.8 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Golgin_A5 PF09787.9 CBY35693.1 - 0.0052 16.3 11.0 0.011 15.2 11.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF745 PF05335.13 CBY35693.1 - 0.009 15.8 0.7 0.009 15.8 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Seadorna_VP7 PF07387.11 CBY35693.1 - 0.02 14.0 0.0 0.054 12.5 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 T4SS PF07996.11 CBY35693.1 - 0.025 15.0 1.6 0.056 13.9 1.6 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins DUF4407 PF14362.6 CBY35693.1 - 0.027 13.8 7.6 0.049 13.0 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CBY35693.1 - 0.042 13.9 14.8 0.18 11.9 14.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APH PF01636.23 CBY35693.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHASE7 PF17151.4 CBY35693.1 - 0.064 12.9 0.9 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain Filament PF00038.21 CBY35693.1 - 0.072 12.7 11.0 0.12 11.9 11.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein Tho2 PF11262.8 CBY35693.1 - 0.078 12.2 2.9 0.14 11.3 2.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FliJ PF02050.16 CBY35693.1 - 0.098 12.9 8.9 0.65 10.2 2.0 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 CBY35693.1 - 0.29 10.6 5.6 0.56 9.7 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CBY35693.1 - 0.33 11.0 19.2 0.11 12.6 8.0 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding LPP PF04728.13 CBY35693.1 - 0.51 10.8 4.5 3.7 8.0 0.4 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 CBY35693.1 - 0.59 10.4 7.1 1.6 9.1 0.7 2.7 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 CBY35693.1 - 2.1 8.4 14.9 0.033 14.3 4.2 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CCDC-167 PF15188.6 CBY35693.1 - 2.6 8.4 6.6 7.8 6.9 6.6 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 THOC7 PF05615.13 CBY35693.1 - 3.6 7.9 13.3 63 3.9 13.4 2.4 1 1 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.12 CBY35693.1 - 4 8.1 8.2 20 5.9 1.3 2.9 2 0 0 2 2 2 0 SlyX TBCA PF02970.16 CBY35693.1 - 6.8 7.1 14.9 0.83 10.0 9.8 2.2 2 0 0 2 2 1 0 Tubulin binding cofactor A Fib_alpha PF08702.10 CBY35693.1 - 7.9 6.7 8.8 22 5.2 8.8 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBY35693.1 - 7.9 5.6 8.6 22 4.1 8.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.8 CBY35693.1 - 8.1 6.7 15.3 1.3 9.2 10.5 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 CBY35693.1 - 9.6 5.5 13.6 44 3.3 13.6 1.9 1 1 0 1 1 1 0 FAM76 protein Na_Ca_ex PF01699.24 CBY35694.1 - 1.1e-15 57.9 3.5 1.4e-15 57.6 3.5 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4132 PF13569.6 CBY35695.1 - 0.16 11.7 1.1 2.7 7.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4132) Na_Ca_ex PF01699.24 CBY35696.1 - 3.6e-14 53.0 13.2 4.8e-14 52.6 13.2 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein VWA PF00092.28 CBY35697.1 - 4.2e-15 56.4 0.7 1.6e-08 35.0 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 CBY35698.1 - 2.3e-11 44.3 0.0 4.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY35698.1 - 8.5e-08 32.8 0.0 4.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain DUF1515 PF07439.11 CBY35699.1 - 0.14 12.2 0.2 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) KH_1 PF00013.29 CBY35700.1 - 2.4e-27 94.6 0.4 1.1e-14 54.0 0.7 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY35700.1 - 4.2e-08 32.9 1.3 7.8e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 CBY35700.1 - 6.6e-06 25.9 0.5 0.025 14.5 0.1 2.7 2 1 0 2 2 2 2 KH domain DUF4537 PF15057.6 CBY35700.1 - 0.031 14.3 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) KH_5 PF13184.6 CBY35700.1 - 0.043 13.9 0.4 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain Rox3 PF08633.10 CBY35700.1 - 0.062 13.6 1.4 0.1 12.9 1.4 1.3 1 0 0 1 1 1 0 Rox3 mediator complex subunit RNR_inhib PF08591.10 CBY35700.1 - 0.08 14.2 0.8 0.18 13.1 0.8 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor HAUS6_N PF14661.6 CBY35700.1 - 0.14 11.7 3.9 0.21 11.2 3.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMEM171 PF15471.6 CBY35701.1 - 0.17 10.8 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein family 171 OAD_gamma PF04277.13 CBY35701.1 - 0.27 11.8 0.6 0.32 11.6 0.6 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PAP2_C PF14360.6 CBY35702.1 - 3.4e-23 82.0 13.9 3.4e-23 82.0 13.9 2.3 2 0 0 2 2 2 2 PAP2 superfamily C-terminal PAP2 PF01569.21 CBY35702.1 - 1.1e-05 25.3 2.9 2.2e-05 24.2 2.9 1.5 1 0 0 1 1 1 1 PAP2 superfamily adh_short_C2 PF13561.6 CBY35704.1 - 2.8e-52 177.6 0.3 3.2e-52 177.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY35704.1 - 1.5e-44 151.8 0.5 2.7e-44 151.0 0.6 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CBY35704.1 - 7e-09 35.9 0.4 8.9e-09 35.5 0.4 1.1 1 0 0 1 1 1 1 KR domain PHD PF00628.29 CBY35705.1 - 1.2e-16 60.3 23.6 1.3e-09 37.8 5.2 2.4 1 1 1 2 2 2 2 PHD-finger PHD_2 PF13831.6 CBY35705.1 - 0.00046 19.7 0.3 0.00046 19.7 0.3 3.0 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.22 CBY35705.1 - 0.025 14.5 22.8 0.052 13.4 4.7 2.8 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3458 PF11940.8 CBY35705.1 - 0.077 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold zf-PHD-like PF15446.6 CBY35705.1 - 0.13 11.9 13.6 0.23 11.1 1.9 2.6 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Tnp_22_trimer PF17489.2 CBY35705.1 - 0.37 10.8 4.1 1.2 9.2 4.1 1.9 1 0 0 1 1 1 0 L1 transposable element trimerization domain Zf_RING PF16744.5 CBY35705.1 - 2.1 8.5 25.5 8.3 6.6 7.1 3.0 1 1 1 2 2 2 0 KIAA1045 RING finger SET PF00856.28 CBY35706.1 - 0.0017 18.8 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 SET domain TAF6_C PF07571.13 CBY35707.1 - 1.7e-23 82.7 0.1 3.1e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CBY35707.1 - 1e-21 76.8 0.4 2.4e-20 72.5 0.1 2.7 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBY35707.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 2.8 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Sulfotransfer_2 PF03567.14 CBY35708.1 - 0.00098 19.1 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family SLIDE PF09111.10 CBY35708.1 - 0.029 14.4 0.2 0.075 13.1 0.1 1.8 1 1 0 1 1 1 0 SLIDE Sulfotransfer_2 PF03567.14 CBY35709.1 - 5.4e-21 75.6 2.8 7.3e-21 75.2 2.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family PQ-loop PF04193.14 CBY35710.1 - 3.5e-30 103.6 3.8 3.5e-17 61.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CBY35710.1 - 0.0022 18.8 9.6 0.43 11.4 5.5 2.3 2 0 0 2 2 2 2 ER lumen protein retaining receptor Met_10 PF02475.16 CBY35711.1 - 1.6e-27 96.6 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CBY35711.1 - 3.1e-06 26.9 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBY35711.1 - 0.00021 21.9 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY35711.1 - 0.0094 15.5 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CBY35711.1 - 0.013 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CBY35711.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBY35711.1 - 0.027 15.1 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CBY35711.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 CBY35711.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 CBY35711.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CBY35711.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Stathmin PF00836.19 CBY35712.1 - 0.93 9.5 13.7 0.17 11.9 6.9 2.5 2 1 0 2 2 2 0 Stathmin family Sod_Cu PF00080.20 CBY35715.1 - 1.4e-28 99.8 2.3 2.2e-28 99.2 2.3 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CdiA_C PF18451.1 CBY35715.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain MARVEL PF01284.23 CBY35716.1 - 0.0073 16.3 7.7 0.0099 15.9 7.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain CTV_P6 PF06706.11 CBY35716.1 - 0.037 13.7 0.6 0.1 12.3 0.6 1.9 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DUF3976 PF13121.6 CBY35716.1 - 0.78 9.9 3.1 0.72 10.0 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) Laminin_N PF00055.17 CBY35717.1 - 4.8e-61 206.3 0.1 4.8e-61 206.3 0.1 2.7 2 0 0 2 2 2 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY35717.1 - 6e-18 64.7 65.1 6.3e-06 26.2 18.1 4.4 3 1 0 3 3 3 3 Laminin EGF domain F5_F8_type_C PF00754.25 CBY35717.1 - 2.5e-05 24.4 1.4 7.9e-05 22.8 0.1 2.6 3 0 0 3 3 3 1 F5/8 type C domain Laminin_G_2 PF02210.24 CBY35717.1 - 0.028 15.0 0.1 0.098 13.2 0.1 2.0 1 0 0 1 1 1 0 Laminin G domain TIG_2 PF18020.1 CBY35717.1 - 0.069 13.8 1.5 0.2 12.3 1.5 1.8 1 0 0 1 1 1 0 TIG domain found in plexin NPCC PF08058.11 CBY35718.1 - 1.7 8.7 3.4 1.7 8.7 1.3 2.0 2 0 0 2 2 2 0 Nuclear pore complex component DUF4473 PF14747.6 CBY35719.1 - 0.018 15.6 1.7 0.066 13.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF3983 PF13137.6 CBY35722.1 - 0.46 10.3 4.1 29 4.6 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) FMO-like PF00743.19 CBY35723.1 - 6.5e-39 133.7 0.1 1.2e-30 106.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CBY35723.1 - 7.1e-19 68.2 0.0 1.7e-16 60.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBY35723.1 - 1.1e-08 34.6 0.1 3.5e-07 29.7 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CBY35723.1 - 2.4e-08 33.6 0.0 3.2e-07 29.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY35723.1 - 7.9e-08 32.4 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBY35723.1 - 2.8e-05 23.9 0.0 0.088 12.4 0.2 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CBY35723.1 - 7.1e-05 23.3 0.1 0.15 12.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBY35723.1 - 0.0029 17.6 0.3 0.081 12.9 0.1 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CBY35723.1 - 0.0074 15.0 0.4 0.12 11.1 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 CBY35723.1 - 0.017 14.3 0.3 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 CBY35723.1 - 0.025 14.6 0.1 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CBY35723.1 - 0.036 13.2 0.2 0.064 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CBY35723.1 - 0.05 13.0 0.2 8.6 5.7 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 CBY35723.1 - 0.063 12.6 0.3 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 CBY35723.1 - 0.24 10.6 0.8 0.88 8.7 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Titin_Ig-rpts PF06582.12 CBY35724.1 - 0.11 12.5 1.0 0.26 11.3 1.0 1.6 1 0 0 1 1 1 0 Titin repeat Nup160 PF11715.8 CBY35727.1 - 4.3e-14 52.1 0.3 6e-14 51.6 0.3 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 HIG_1_N PF04588.13 CBY35728.1 - 1.7e-05 24.9 0.0 3.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region KIAA1430 PF13879.6 CBY35730.1 - 2.3e-10 41.1 12.6 3.3e-10 40.6 12.6 1.3 1 0 0 1 1 1 1 KIAA1430 homologue Miga PF10265.9 CBY35730.1 - 4.8 6.0 7.1 5.3 5.9 7.1 1.1 1 0 0 1 1 1 0 Mitoguardin CD20 PF04103.15 CBY35731.1 - 0.0021 18.2 5.2 0.0029 17.7 5.2 1.3 1 0 0 1 1 1 1 CD20-like family Tetraspanin PF00335.20 CBY35731.1 - 0.2 11.4 13.9 0.3 10.8 13.9 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 CBY35731.1 - 4.5 7.8 9.6 89 3.6 9.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) TSP_1 PF00090.19 CBY35732.1 - 0.00017 21.7 7.6 0.00038 20.6 7.6 1.7 1 1 0 1 1 1 1 Thrombospondin type 1 domain CAP PF00188.26 CBY35735.1 - 2.9e-10 41.1 0.7 5.2e-10 40.2 0.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CXCXC PF03128.14 CBY35735.1 - 4.8 7.9 24.7 0.13 12.7 2.5 5.1 4 0 0 4 4 4 0 CXCXC repeat Peptidase_M13_N PF05649.13 CBY35736.1 - 2.2e-59 202.1 0.0 5.4e-34 118.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 CBY35736.1 - 5.8e-47 160.0 2.3 1.1e-46 159.0 2.3 1.4 1 0 0 1 1 1 1 Peptidase family M13 Pkinase PF00069.25 CBY35736.1 - 1.7e-40 139.0 0.0 3.3e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35736.1 - 8e-26 90.9 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY35736.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY35736.1 - 0.0025 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EcKinase PF02958.20 CBY35736.1 - 0.055 12.8 0.1 0.17 11.2 0.0 1.8 3 0 0 3 3 3 0 Ecdysteroid kinase S_layer_N PF05123.12 CBY35736.1 - 0.23 11.3 1.0 0.65 9.8 0.1 2.0 2 0 0 2 2 2 0 S-layer like family, N-terminal region SPECT1 PF18680.1 CBY35736.1 - 3 7.5 8.5 0.61 9.7 0.0 3.2 4 0 0 4 4 4 0 Plasmodium host cell traversal SPECT1 Pkinase PF00069.25 CBY35737.1 - 0.0085 15.5 0.0 0.0087 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 CBY35737.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 HEAT-like repeat Torsin PF06309.11 CBY35738.1 - 2.2e-28 98.9 0.0 4.3e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.14 CBY35738.1 - 0.0051 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBY35738.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CBY35738.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CBY35738.1 - 0.029 14.8 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBY35738.1 - 0.034 14.2 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CBY35738.1 - 0.039 14.0 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CBY35738.1 - 0.063 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 CBY35738.1 - 0.066 13.5 0.0 0.78 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY35738.1 - 0.092 13.1 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 CBY35738.1 - 0.18 10.5 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein BolA PF01722.18 CBY35739.1 - 2.2e-15 56.6 0.2 1.8e-14 53.8 0.2 1.9 1 1 0 1 1 1 1 BolA-like protein SRP68 PF16969.5 CBY35740.1 - 4.7e-13 49.0 2.1 8.8e-13 48.1 1.9 1.5 1 1 1 2 2 2 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 CBY35740.1 - 0.002 17.0 3.9 0.0047 15.8 3.7 1.6 1 1 1 2 2 2 1 BRO1-like domain Ald_Xan_dh_C2 PF02738.18 CBY35741.1 - 2.4e-65 221.1 0.1 3e-65 220.7 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase zf-3CxxC_2 PF17180.4 CBY35742.1 - 1.8e-22 79.8 11.6 1.8e-22 79.8 11.6 4.5 5 0 0 5 5 5 2 Zinc-binding domain RVT_3 PF13456.6 CBY35744.1 - 0.0071 16.2 0.8 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase-like Lectin_leg-like PF03388.13 CBY35745.1 - 8.7e-64 215.0 0.0 1.3e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CBY35745.1 - 2.3e-08 34.3 0.8 3.5e-08 33.7 0.8 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CBY35745.1 - 0.012 15.2 0.0 0.094 12.2 0.0 2.1 2 1 0 2 2 2 0 Legume lectin domain Ribosomal_S2 PF00318.20 CBY35746.1 - 1.5e-25 89.7 0.2 2.7e-13 49.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CBY35746.1 - 1.1e-05 26.7 9.7 2.4e-05 25.6 9.7 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Kinesin PF00225.23 CBY35747.1 - 1e-107 360.0 0.5 1e-107 360.0 0.5 2.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY35747.1 - 8.1e-22 77.8 0.2 8.1e-22 77.8 0.2 4.1 2 1 2 4 4 4 1 Microtubule binding WD40 PF00400.32 CBY35747.1 - 9e-09 35.8 2.9 0.013 16.4 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat EF-hand_1 PF00036.32 CBY35748.1 - 7.4e-28 94.0 14.5 9.3e-08 31.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY35748.1 - 2e-26 92.2 6.2 3.2e-13 49.9 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY35748.1 - 2.1e-22 77.1 10.5 3.4e-07 29.7 0.0 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CBY35748.1 - 1e-20 73.3 13.1 3.7e-11 42.7 1.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY35748.1 - 7.1e-16 58.3 0.2 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY35748.1 - 5.3e-06 25.7 17.2 0.00055 19.3 0.7 5.0 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CBY35748.1 - 1.2e-05 25.1 5.3 0.006 16.5 1.2 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY35748.1 - 0.00016 22.5 0.3 0.1 13.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CBY35748.1 - 0.001 19.3 0.7 0.88 10.0 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CBY35748.1 - 0.0019 18.4 0.2 0.0067 16.6 0.1 1.9 1 1 1 2 2 2 1 Dockerin type I domain SUB1_ProdP9 PF18213.1 CBY35748.1 - 0.0027 17.5 1.3 0.01 15.7 0.3 2.1 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 CBY35748.1 - 0.026 14.4 3.0 3.5 7.5 0.1 2.7 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CBY35748.1 - 0.035 12.7 0.1 0.26 9.8 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.13 CBY35748.1 - 0.038 13.9 0.2 8.4 6.3 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein FlgD PF03963.14 CBY35748.1 - 0.041 14.2 0.1 0.073 13.4 0.1 1.6 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TerB PF05099.13 CBY35748.1 - 0.072 13.0 3.8 5.9 6.8 0.6 3.0 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CBY35748.1 - 0.13 12.9 2.8 0.13 12.9 0.8 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CBY35748.1 - 0.24 11.7 4.0 0.45 10.8 1.9 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Malate_DH PF12434.8 CBY35748.1 - 0.51 10.4 3.7 0.22 11.6 0.8 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Lactamase_B PF00753.27 CBY35751.1 - 2.5e-13 50.5 5.1 9.3e-11 42.1 5.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY35751.1 - 0.027 14.0 1.9 0.048 13.2 1.9 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain EF-hand_7 PF13499.6 CBY35752.1 - 5.2e-16 58.8 1.5 2.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY35752.1 - 1.3e-13 49.7 1.4 0.0025 17.6 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CBY35752.1 - 5.2e-12 44.4 1.2 0.022 14.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBY35752.1 - 1.3e-09 38.3 0.1 4.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY35752.1 - 2.4e-09 36.9 0.4 4.4e-06 26.4 0.0 3.5 2 1 2 4 4 4 1 EF-hand domain pair EF-hand_11 PF08976.11 CBY35752.1 - 0.00077 20.3 0.3 0.0021 18.9 0.1 1.7 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 CBY35752.1 - 0.0013 17.3 0.1 0.0016 17.1 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 CBY35752.1 - 0.0086 16.0 1.3 1.3 8.9 0.5 2.4 1 1 1 2 2 2 2 Caleosin related protein PHB_acc_N PF07879.11 CBY35752.1 - 0.014 15.4 0.4 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain EAL PF00563.20 CBY35752.1 - 0.059 12.9 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 EAL domain DUF1456 PF07308.13 CBY35752.1 - 0.082 13.3 0.3 4.1 7.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) EFhand_Ca_insen PF08726.10 CBY35752.1 - 0.087 12.9 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF99 PF01949.16 CBY35752.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 PDDEXK_1 PF12705.7 CBY35753.1 - 0.0005 20.1 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily UDPGT PF00201.18 CBY35754.1 - 9.1e-54 183.1 0.3 1e-53 182.9 0.3 1.0 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UAA PF08449.11 CBY35755.1 - 3.4e-18 65.9 8.1 3.9e-18 65.7 8.1 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY35755.1 - 7.6e-09 35.3 7.2 1e-08 34.9 7.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY35755.1 - 0.00019 21.6 5.2 0.00019 21.6 5.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CBY35755.1 - 0.00078 18.8 6.0 0.0018 17.6 6.0 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF1129 PF06570.11 CBY35755.1 - 0.032 13.7 2.1 0.038 13.5 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2417 PF10329.9 CBY35755.1 - 0.032 13.6 1.5 0.032 13.6 0.3 1.6 1 1 0 1 1 1 0 Region of unknown function (DUF2417) 7tm_2 PF00002.24 CBY35757.1 - 9.1e-43 146.3 17.9 1.1e-42 146.0 17.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PAP_central PF04928.17 CBY35757.1 - 0.16 11.0 0.6 0.23 10.4 0.6 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain Orn_Arg_deC_N PF02784.16 CBY35759.1 - 5e-18 65.4 0.0 5.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_Arg_deC_N PF02784.16 CBY35760.1 - 1.2e-18 67.5 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBY35760.1 - 1.2e-11 44.7 0.0 4.5e-11 42.9 0.0 1.9 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ank_2 PF12796.7 CBY35761.1 - 1.5e-30 105.6 1.0 4.3e-15 56.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY35761.1 - 1.4e-26 89.6 0.0 3.3e-05 23.9 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 CBY35761.1 - 8.2e-25 86.9 1.3 9.6e-07 29.2 0.0 4.6 1 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY35761.1 - 4.3e-20 71.5 0.0 6.5e-06 26.3 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBY35761.1 - 4.4e-18 64.9 0.0 6.9e-05 23.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 CBY35762.1 - 5.7e-19 68.2 0.6 4.5e-10 39.9 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35762.1 - 6.6e-17 61.9 0.0 5.7e-15 55.7 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY35762.1 - 2e-14 52.3 0.1 5.2e-05 23.3 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 CBY35762.1 - 7.3e-13 48.3 1.3 4.9e-05 23.6 0.6 3.1 2 1 1 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY35762.1 - 6.4e-11 42.3 0.3 4.7e-08 33.2 0.6 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MCM_N PF14551.6 CBY35763.1 - 2.1e-15 57.2 0.5 2.5e-15 56.9 0.5 1.1 1 0 0 1 1 1 1 MCM N-terminal domain MCM_OB PF17207.3 CBY35763.1 - 4.6e-07 29.7 0.1 7.6e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain Tetradecapep PF08187.11 CBY35763.1 - 0.46 10.6 2.5 75 3.7 0.6 3.3 3 0 0 3 3 3 0 Myoactive tetradecapeptides family Thymidylat_synt PF00303.19 CBY35764.1 - 1e-117 392.0 0.0 1.2e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HMGL-like PF00682.19 CBY35765.1 - 5.3e-54 183.5 0.0 6.1e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like HisKA_3 PF07730.13 CBY35765.1 - 0.39 11.3 1.3 0.58 10.7 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase RRM_1 PF00076.22 CBY35766.1 - 6.6e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOC3p PF07540.11 CBY35767.1 - 3.9e-23 81.7 0.2 3.9e-23 81.7 0.2 2.8 2 0 0 2 2 2 1 Nucleolar complex-associated protein Linker_histone PF00538.19 CBY35767.1 - 1.9 8.9 8.2 15 6.0 4.5 3.1 2 0 0 2 2 2 0 linker histone H1 and H5 family CBF PF03914.17 CBY35768.1 - 0.022 14.8 0.7 0.057 13.4 0.7 1.7 1 1 0 1 1 1 0 CBF/Mak21 family Nucleoporin_N PF08801.11 CBY35769.1 - 1.4e-74 251.5 0.0 2e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CBY35769.1 - 4.2e-19 68.7 0.6 6.8e-19 68.0 0.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DIPSY PF11763.8 CBY35769.1 - 0.16 12.1 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Ribosomal_L22 PF00237.19 CBY35770.1 - 2.7e-40 136.8 0.1 4.6e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L2_C PF03947.18 CBY35771.1 - 3.2e-43 146.9 3.5 5.1e-43 146.3 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CBY35771.1 - 1.9e-15 56.6 0.2 5e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TSP_1 PF00090.19 CBY35772.1 - 1.8e-16 60.1 76.0 2.5e-09 37.2 10.9 6.8 6 0 0 6 6 6 4 Thrombospondin type 1 domain ADAM_CR_2 PF17771.1 CBY35772.1 - 6.7e-14 52.2 9.0 6.7e-14 52.2 9.0 5.6 4 2 1 5 5 5 2 ADAM cysteine-rich domain Reprolysin PF01421.19 CBY35772.1 - 3.8e-12 46.5 0.5 8.3e-12 45.4 0.5 1.5 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 CBY35772.1 - 1.3e-06 29.0 0.0 2.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY35772.1 - 4.4e-06 27.0 0.1 4.4e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CBY35772.1 - 0.00072 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CBY35772.1 - 0.00098 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_spacer1 PF05986.14 CBY35772.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 ADAM-TS Spacer 1 DHHC PF01529.20 CBY35773.1 - 1e-36 126.0 16.2 1e-36 126.0 16.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3810 PF12725.7 CBY35773.1 - 8.9 5.6 9.7 3.8 6.8 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LAP1C PF05609.12 CBY35774.1 - 0.029 13.5 1.2 0.036 13.2 1.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) HSP70 PF00012.20 CBY35776.1 - 2.1e-63 214.5 18.3 2.1e-63 214.5 18.3 2.6 1 1 2 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBY35776.1 - 0.0056 15.5 5.2 0.028 13.2 5.2 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Hfq PF17209.3 CBY35776.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Hfq protein DUF2518 PF10726.9 CBY35776.1 - 0.098 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of function (DUF2518) EF-hand_1 PF00036.32 CBY35777.1 - 4.1e-12 44.7 4.5 2.6e-06 26.6 0.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY35777.1 - 1.9e-10 41.0 4.1 2e-09 37.8 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY35777.1 - 2.2e-10 39.6 0.5 0.00023 20.8 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY35777.1 - 3.9e-09 35.6 0.9 0.0026 17.2 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 CBY35777.1 - 1.7e-06 27.9 2.0 8.8e-06 25.6 0.3 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY35777.1 - 0.0075 17.1 1.2 0.14 13.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CBY35777.1 - 0.039 14.2 0.2 0.098 12.9 0.2 1.7 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_8 PF13833.6 CBY35777.1 - 0.043 13.7 2.2 0.18 11.7 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair GST_C_2 PF13410.6 CBY35778.1 - 3.2e-06 27.1 0.1 5.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBY35778.1 - 0.011 16.1 0.0 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY35778.1 - 0.029 14.6 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RecG_N PF17190.4 CBY35778.1 - 0.059 14.1 1.1 0.085 13.6 0.2 1.7 2 0 0 2 2 2 0 RecG N-terminal helical domain Transglut_N PF00868.20 CBY35779.1 - 2.1e-26 92.6 0.0 4.9e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase family Transglut_core PF01841.19 CBY35779.1 - 6.7e-16 58.7 0.1 1.3e-15 57.8 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily SRF-TF PF00319.18 CBY35779.1 - 0.031 13.8 0.1 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) MICSWaP PF17018.5 CBY35779.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Spore wall protein DUF220 PF02713.14 CBY35779.1 - 0.16 12.1 0.4 14 5.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF220 Pyr_redox_dim PF02852.22 CBY35780.1 - 2.7e-22 79.1 0.0 5.4e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 CBY35780.1 - 4.5e-08 32.7 0.0 5.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2b PF00587.25 CBY35782.1 - 2.5e-36 125.3 0.0 4.3e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBY35782.1 - 2.1e-17 63.1 0.0 3.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CBY35782.1 - 1.2e-16 60.5 0.0 2.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CBY35782.1 - 1.7e-10 40.8 0.0 4.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Aa_trans PF01490.18 CBY35784.1 - 1.8e-74 250.9 16.3 1.9e-60 204.7 12.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBY35785.1 - 1.4e-72 244.6 22.7 2e-71 240.9 22.7 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Phage_GPO PF05929.11 CBY35786.1 - 0.04 13.6 16.6 0.045 13.4 16.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Use1 PF09753.9 CBY35786.1 - 0.065 12.9 18.8 0.072 12.8 18.8 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 UPF0242 PF06785.11 CBY35786.1 - 0.17 12.0 27.1 0.46 10.6 27.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CwsA PF10814.8 CBY35786.1 - 0.51 10.5 3.2 0.76 9.9 3.2 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA ING PF12998.7 CBY35786.1 - 0.78 10.4 15.7 26 5.5 15.7 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF3584 PF12128.8 CBY35786.1 - 0.85 7.1 22.7 0.97 6.9 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 CBY35786.1 - 0.9 9.8 25.9 0.69 10.2 11.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ANAPC4 PF12896.7 CBY35786.1 - 1.3 8.5 10.5 0.23 10.9 4.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 FUSC PF04632.12 CBY35786.1 - 2.2 6.7 4.0 2.5 6.5 4.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DHR10 PF18595.1 CBY35786.1 - 2.2 8.3 29.1 1.4 9.0 9.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 CBY35786.1 - 3.5 8.1 23.7 5.5 7.4 19.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 CBY35786.1 - 4.6 6.7 14.5 5.1 6.6 14.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nup88 PF10168.9 CBY35786.1 - 5 4.8 17.7 1.1 7.0 14.5 1.5 1 1 0 1 1 1 0 Nuclear pore component DUF4795 PF16043.5 CBY35786.1 - 6.9 6.2 26.0 98 2.5 26.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 CBY35786.1 - 7.2 6.7 14.1 14 5.8 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2951 PF11166.8 CBY35786.1 - 9.7 6.5 17.5 0.47 10.7 3.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) UPRTase PF14681.6 CBY35787.1 - 1.8e-63 213.7 0.0 2.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBY35787.1 - 0.00034 20.2 0.0 0.00074 19.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PDZ PF00595.24 CBY35789.1 - 6.5e-12 45.6 0.1 1.2e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain DIL PF01843.19 CBY35789.1 - 3e-11 43.5 0.0 7.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 DIL domain PDZ_6 PF17820.1 CBY35789.1 - 2.9e-07 30.2 0.0 5.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY35789.1 - 7.6e-06 26.2 0.1 1.4e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 CBY35790.1 - 7.5e-54 182.9 0.0 9.5e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY35790.1 - 0.00068 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY35790.1 - 0.0031 18.4 0.0 0.0045 17.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY35790.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 DUF1205 PF06722.12 CBY35790.1 - 0.037 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) Glyco_hydro_47 PF01532.20 CBY35792.1 - 2.6e-125 418.9 0.4 6.3e-125 417.6 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Thioredoxin PF00085.20 CBY35792.1 - 3.6e-05 23.7 0.1 8.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2570 PF10828.8 CBY35792.1 - 0.0088 15.9 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Thioredoxin_2 PF13098.6 CBY35792.1 - 0.018 15.5 1.1 0.24 11.8 1.1 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain P5CR_dimer PF14748.6 CBY35792.1 - 0.035 14.4 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation NB-ARC PF00931.22 CBY35793.1 - 0.082 12.1 0.5 0.14 11.3 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain SNF PF00209.18 CBY35794.1 - 1.7e-178 594.6 37.0 1.9e-178 594.4 37.0 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family GAGA_bind PF06217.12 CBY35794.1 - 0.8 9.9 1.5 1.3 9.2 1.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family COesterase PF00135.28 CBY35795.1 - 4e-63 214.1 0.0 6.1e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY35795.1 - 0.00021 21.2 0.0 0.00049 20.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Beta_elim_lyase PF01212.21 CBY35796.1 - 1.5e-11 44.2 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase BTG PF07742.12 CBY35797.1 - 2e-36 124.3 0.0 4.2e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 BTG family Kelch_1 PF01344.25 CBY35798.1 - 1.9e-49 165.0 10.5 1.4e-11 43.7 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBY35798.1 - 2.3e-30 103.9 1.9 5.7e-06 26.4 0.0 6.8 4 2 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBY35798.1 - 1.9e-26 91.8 3.4 1.1e-06 28.7 0.0 6.6 6 0 0 6 6 6 3 Galactose oxidase, central domain BACK PF07707.15 CBY35798.1 - 2.5e-21 75.7 0.4 6.4e-21 74.4 0.4 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 CBY35798.1 - 4.5e-19 68.2 3.1 0.00056 19.9 0.0 5.7 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY35798.1 - 1.1e-16 60.0 3.6 0.0022 17.9 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CBY35798.1 - 4.1e-14 52.2 1.7 0.14 12.2 0.1 6.5 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 CBY35798.1 - 2.7e-12 46.9 2.3 3.8e-07 30.3 0.0 2.8 2 1 1 3 3 3 2 BTB/POZ domain EABR PF12180.8 CBY35798.1 - 0.019 14.6 0.2 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Glycos_transf_2 PF00535.26 CBY35800.1 - 7.9e-28 97.4 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY35800.1 - 8.4e-15 55.2 1.6 5.2e-14 52.6 1.7 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY35800.1 - 0.00022 20.8 0.0 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY35801.1 - 4.5e-21 75.4 1.6 4.4e-20 72.2 1.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.22 CBY35801.1 - 8.1e-07 29.3 0.6 2.1e-06 28.0 0.6 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.14 CBY35801.1 - 1.5e-06 27.8 0.3 3e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 CBY35801.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 CDtoxinA PF03498.14 CBY35801.1 - 0.15 11.6 1.2 2.5 7.7 0.3 2.3 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Macro PF01661.21 CBY35802.1 - 3.5e-41 139.9 0.1 5.4e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Macro domain DUF4202 PF13875.6 CBY35802.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Syja_N PF02383.18 CBY35803.1 - 3e-54 184.5 0.0 4.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CBY35803.1 - 9.3e-12 45.0 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldl_recept_a PF00057.18 CBY35804.1 - 5.5e-14 52.1 56.2 1.7e-09 37.7 16.0 4.6 5 0 0 5 5 5 3 Low-density lipoprotein receptor domain class A Ldl_recept_b PF00058.17 CBY35804.1 - 3.6e-07 30.6 13.0 1 9.9 0.1 8.4 9 0 0 9 9 9 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 CBY35804.1 - 0.00022 20.9 0.5 0.59 9.7 0.0 4.4 5 0 0 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region FXa_inhibition PF14670.6 CBY35804.1 - 0.002 18.3 7.6 0.002 18.3 7.6 5.6 5 0 0 5 5 5 1 Coagulation Factor Xa inhibitory site ATP-synt_C PF00137.21 CBY35805.1 - 2e-11 44.0 14.0 3.1e-11 43.5 14.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Surp PF01805.20 CBY35806.1 - 1.6e-19 69.6 0.1 3.7e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CBY35806.1 - 3.1e-10 39.7 0.0 9.6e-10 38.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY35806.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Clat_adaptor_s PF01217.20 CBY35807.1 - 7.4e-27 94.0 2.0 9.3e-27 93.7 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Trypsin PF00089.26 CBY35808.1 - 6e-93 310.7 3.6 1.9e-37 129.2 0.2 3.2 3 0 0 3 3 3 3 Trypsin CUB PF00431.20 CBY35808.1 - 1.6e-20 73.5 0.2 5.2e-20 71.8 0.1 1.9 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.11 CBY35808.1 - 3.3e-09 37.1 0.0 1.4e-06 28.7 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY35808.1 - 8.3e-07 30.0 0.0 0.00057 20.8 0.0 2.8 2 1 0 2 2 2 2 Trypsin-like peptidase domain Mucin PF01456.17 CBY35808.1 - 1.1 9.2 21.7 1.8 8.6 21.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Transformer PF06495.11 CBY35810.1 - 0.035 14.2 4.1 0.11 12.6 4.1 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1510 PF07423.11 CBY35810.1 - 0.31 11.2 2.4 1.4 9.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) Sulfatase PF00884.23 CBY35811.1 - 3.6e-44 151.4 0.1 4.6e-44 151.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase RNA_pol_Rpb2_6 PF00562.28 CBY35812.1 - 5.4e-100 335.2 0.0 1.2e-99 334.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBY35812.1 - 1.7e-31 109.3 0.1 3e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CBY35812.1 - 1.4e-25 89.2 0.0 3.2e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBY35812.1 - 1e-17 64.3 0.0 3.4e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CBY35812.1 - 1.7e-14 53.6 0.0 3.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CBY35812.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Ion_trans_2 PF07885.16 CBY35813.1 - 2.1e-29 101.3 8.9 5.8e-17 61.4 0.1 2.4 2 1 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY35813.1 - 0.024 13.9 7.7 0.074 12.3 3.2 2.3 1 1 1 2 2 2 0 Ion transport protein Sm_multidrug_ex PF06695.11 CBY35813.1 - 0.06 14.0 0.1 0.087 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative small multi-drug export protein Ion_trans_2 PF07885.16 CBY35814.1 - 1.3e-27 95.6 7.6 8.5e-16 57.7 0.2 2.4 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CBY35814.1 - 0.02 14.1 2.1 0.055 12.7 0.1 2.1 2 0 0 2 2 2 0 Ion transport protein Cadherin PF00028.17 CBY35814.1 - 0.075 13.5 0.1 12 6.4 0.0 3.4 3 0 0 3 3 3 0 Cadherin domain DUF2808 PF10989.8 CBY35814.1 - 0.2 11.6 1.4 0.71 9.9 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2808) zf-C2H2_10 PF16588.5 CBY35814.1 - 0.27 11.0 1.2 0.64 9.8 1.2 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger Cadherin PF00028.17 CBY35815.1 - 5.5e-05 23.5 12.8 1 9.9 0.3 8.1 8 1 0 8 8 8 4 Cadherin domain SLT PF01464.20 CBY35816.1 - 0.00022 20.9 0.0 0.0006 19.5 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain SAS4 PF15460.6 CBY35816.1 - 0.2 11.8 0.0 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Trefoil PF00088.18 CBY35817.1 - 3.5e-21 74.8 42.2 2.8e-08 33.5 1.5 5.4 5 0 0 5 5 5 5 Trefoil (P-type) domain DUF5442 PF17514.2 CBY35817.1 - 0.074 13.3 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Glyco_hydro_9 PF00759.19 CBY35818.1 - 5.1e-51 174.4 2.0 5.1e-51 174.4 2.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 EGF PF00008.27 CBY35818.1 - 4.3e-05 23.7 9.5 0.00012 22.3 9.5 1.9 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 CBY35818.1 - 0.064 13.4 4.4 0.15 12.2 4.4 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 CBY35818.1 - 0.069 13.5 11.2 0.15 12.4 11.2 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 CBY35818.1 - 0.42 11.3 8.8 0.19 12.4 5.7 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY35819.1 - 2.3e-187 607.1 427.3 8e-11 42.0 9.0 29.4 30 1 0 30 30 30 25 Calcium-binding EGF domain EGF_3 PF12947.7 CBY35819.1 - 1.4e-129 422.0 440.3 6.5e-10 39.0 10.7 28.8 29 0 0 29 29 29 27 EGF domain cEGF PF12662.7 CBY35819.1 - 1.8e-97 318.7 242.7 1.8e-07 31.0 2.4 27.8 28 0 0 28 28 28 23 Complement Clr-like EGF-like EGF PF00008.27 CBY35819.1 - 1e-55 185.6 364.7 4.5e-06 26.9 8.9 29.3 28 0 0 28 28 28 24 EGF-like domain hEGF PF12661.7 CBY35819.1 - 5.7e-34 115.6 303.9 8.6e-05 23.0 1.7 30.8 30 1 0 30 30 30 22 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY35819.1 - 7.6e-25 86.9 365.3 0.035 14.4 10.0 28.2 18 9 9 27 27 27 20 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY35819.1 - 1.2e-22 79.7 340.0 0.0007 19.6 4.9 27.1 28 1 1 29 29 29 18 MSP1 EGF domain 1 VWA PF00092.28 CBY35819.1 - 8e-18 65.3 0.0 1.3e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Plasmod_Pvs28 PF06247.11 CBY35819.1 - 0.0067 16.7 330.7 0.054 13.8 7.5 27.3 27 1 1 28 28 28 16 Pvs28 EGF domain CLAMP PF14769.6 CBY35819.1 - 0.068 13.6 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Serinc PF03348.15 CBY35820.1 - 6.6e-36 124.2 23.4 6.8e-33 114.2 19.3 2.0 2 0 0 2 2 2 2 Serine incorporator (Serinc) Sterol-sensing PF12349.8 CBY35820.1 - 3.8 7.4 11.8 0.57 10.0 1.6 2.6 3 0 0 3 3 3 0 Sterol-sensing domain of SREBP cleavage-activation Ank_5 PF13857.6 CBY35822.1 - 4.5e-22 77.8 0.4 8e-09 35.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY35822.1 - 5e-22 78.3 0.1 6.4e-12 45.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY35822.1 - 8.9e-20 70.8 0.2 2.5e-11 43.9 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY35822.1 - 7.1e-16 57.9 0.1 2.3e-08 34.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBY35822.1 - 2.4e-11 42.8 0.1 5.2e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PUFD PF16553.5 CBY35822.1 - 0.004 17.2 0.4 0.053 13.6 0.4 2.5 1 1 0 1 1 1 1 BCORL-PCGF1-binding domain Neuralized PF07177.12 CBY35823.1 - 7.6e-14 52.0 0.1 1e-13 51.6 0.1 1.2 1 0 0 1 1 1 1 Neuralized MRP-63 PF14978.6 CBY35824.1 - 2e-05 25.1 1.0 0.00018 22.0 0.1 2.4 1 1 1 2 2 2 1 Mitochondrial ribosome protein 63 7tm_1 PF00001.21 CBY35825.1 - 7.5e-37 127.1 12.1 3.7e-20 72.4 4.0 2.3 2 1 0 2 2 2 2 7 transmembrane receptor (rhodopsin family) Chromo PF00385.24 CBY35826.1 - 6.5e-23 80.4 10.1 1.1e-10 41.2 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY35826.1 - 0.0026 17.6 5.4 0.34 10.8 0.1 2.7 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain AT_hook PF02178.19 CBY35826.1 - 0.005 16.6 23.5 0.26 11.3 4.4 4.3 2 1 1 3 3 3 3 AT hook motif Mtf2_C PF14061.6 CBY35826.1 - 0.095 12.9 0.8 3.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 GIY-YIG PF01541.24 CBY35826.1 - 1.4 9.2 7.1 0.79 10.0 4.5 1.9 2 0 0 2 2 2 0 GIY-YIG catalytic domain AT_hook PF02178.19 CBY35827.1 - 0.0027 17.4 29.3 0.055 13.4 4.4 4.5 3 2 1 4 4 4 3 AT hook motif zf-H2C2_2 PF13465.6 CBY35828.1 - 4e-09 36.5 35.3 0.00068 20.0 10.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY35828.1 - 1.3e-06 28.5 34.5 0.0048 17.3 8.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35828.1 - 3.9e-06 27.2 30.1 0.031 15.1 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY35828.1 - 0.0046 16.9 4.8 0.0046 16.9 4.8 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.15 CBY35828.1 - 0.097 12.7 0.0 0.097 12.7 0.0 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DUF1966 PF09260.11 CBY35828.1 - 0.15 12.3 0.5 0.36 11.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) zf-met PF12874.7 CBY35828.1 - 0.24 11.9 15.3 0.97 9.9 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Acyltransf_C PF16076.5 CBY35828.1 - 0.36 11.0 2.7 9.4 6.4 0.7 2.9 2 1 0 2 2 2 0 Acyltransferase C-terminus zf-C2H2_jaz PF12171.8 CBY35828.1 - 0.63 10.4 0.1 0.63 10.4 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 CBY35828.1 - 1 9.3 11.9 1.6 8.7 0.3 3.5 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CBY35828.1 - 1.6 8.8 16.4 1.5 8.9 0.9 3.5 1 1 2 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 CBY35828.1 - 1.6 8.7 23.7 0.95 9.4 1.6 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-CHCC PF10276.9 CBY35828.1 - 7.9 6.6 15.1 0.33 11.0 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2 PF00096.26 CBY35832.1 - 2.4e-07 30.8 6.7 0.00021 21.6 1.5 6.8 6 2 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY35832.1 - 0.00011 22.7 8.2 0.0065 17.2 0.2 6.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY35832.1 - 0.00012 22.4 6.4 0.0074 16.7 0.2 5.9 5 1 1 6 6 6 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY35832.1 - 0.00013 22.2 16.2 0.0097 16.2 0.4 3.8 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding LisH PF08513.11 CBY35832.1 - 0.009 15.9 0.1 0.026 14.5 0.1 1.8 1 0 0 1 1 1 1 LisH zf-C2H2_8 PF15909.5 CBY35832.1 - 0.013 15.8 9.8 0.013 15.8 9.8 3.5 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-met PF12874.7 CBY35832.1 - 0.015 15.6 0.6 0.015 15.6 0.6 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY35832.1 - 0.016 15.2 2.3 0.016 15.2 2.3 3.9 5 0 0 5 5 4 0 C2H2-type zinc finger HMG14_17 PF01101.18 CBY35832.1 - 1.7 9.7 7.3 2.6 9.1 6.5 1.7 1 1 0 1 1 1 0 HMG14 and HMG17 zf_UBZ PF18439.1 CBY35832.1 - 2.4 7.8 10.7 0.38 10.4 0.2 3.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CBY35832.1 - 2.9 8.1 9.3 0.73 10.0 1.0 3.4 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 CBY35832.1 - 5.8 6.9 11.5 9.2 6.3 0.1 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type PX PF00787.24 CBY35833.1 - 2.4e-05 24.3 3.0 4.3e-05 23.5 3.0 1.4 1 0 0 1 1 1 1 PX domain PIN_5 PF08745.11 CBY35833.1 - 0.13 11.6 0.3 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 PINc domain ribonuclease Thioredoxin_6 PF13848.6 CBY35834.1 - 7.1e-42 143.4 2.5 1.3e-37 129.5 0.9 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBY35834.1 - 2.5e-20 72.4 0.1 9e-20 70.6 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 CBY35834.1 - 7.9e-09 35.0 1.0 1.3e-08 34.3 1.0 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 CBY35834.1 - 1.2e-06 29.0 0.1 4e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY35834.1 - 1.8e-05 24.2 0.3 3.9e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY35834.1 - 0.0032 17.8 1.4 0.052 13.9 0.2 3.3 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY35834.1 - 0.0051 17.0 0.1 0.42 10.8 0.1 3.1 3 0 0 3 3 3 1 Thioredoxin-like DUF4905 PF16248.5 CBY35834.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) RA PF00788.23 CBY35835.1 - 2e-11 44.4 0.0 5.4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 CBY35835.1 - 0.014 15.3 3.8 0.025 14.4 3.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CBY35835.1 - 0.1 12.2 0.8 0.22 11.1 0.8 1.5 1 0 0 1 1 1 0 PHD-finger Stap_Strp_tox_C PF02876.17 CBY35835.1 - 0.13 12.5 1.8 1.7 9.0 0.1 2.8 3 0 0 3 3 3 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Vps51 PF08700.11 CBY35836.1 - 9.3e-23 80.1 4.4 3.3e-22 78.3 3.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 CBY35836.1 - 6e-16 58.8 10.2 6e-16 58.8 10.2 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Dor1 PF04124.12 CBY35836.1 - 2.1e-11 43.1 9.3 2.5e-11 42.9 7.9 1.8 1 1 0 1 1 1 1 Dor1-like family COG2 PF06148.11 CBY35836.1 - 0.00021 21.4 4.1 0.00021 21.4 4.1 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 CBY35836.1 - 0.00049 19.5 6.4 0.00049 19.5 6.4 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Baculo_PEP_C PF04513.12 CBY35836.1 - 0.16 12.0 4.6 0.87 9.6 0.2 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tubulin_2 PF13809.6 CBY35836.1 - 0.18 11.0 0.5 0.37 9.9 0.5 1.5 1 0 0 1 1 1 0 Tubulin like KxDL PF10241.9 CBY35836.1 - 0.86 9.9 4.5 7.7 6.9 0.5 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 CBY35836.1 - 1.8 9.2 7.6 0.82 10.3 0.6 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 CBY35836.1 - 4.3 7.2 5.7 4.5 7.2 0.4 3.5 4 0 0 4 4 4 0 DASH complex subunit Dam1 Occludin_ELL PF07303.13 CBY35836.1 - 8.1 7.2 8.4 2.7 8.7 1.3 3.7 2 2 2 4 4 4 0 Occludin homology domain Pcc1 PF09341.10 CBY35837.1 - 3.2e-20 72.0 0.2 3.5e-20 71.9 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Pkinase_Tyr PF07714.17 CBY35838.1 - 8.9e-50 169.4 0.0 2.6e-49 167.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35838.1 - 1.7e-49 168.6 0.0 3.3e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY35838.1 - 0.0078 15.0 0.3 0.022 13.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Ribosomal_L44 PF00935.19 CBY35838.1 - 1.1 9.8 8.0 11 6.6 3.5 2.7 2 0 0 2 2 2 0 Ribosomal protein L44 Aminotran_1_2 PF00155.21 CBY35839.1 - 8.1e-50 170.0 0.0 1.3e-49 169.3 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBY35839.1 - 0.0009 18.3 0.0 0.0019 17.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY35839.1 - 0.019 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CBY35839.1 - 0.042 12.4 0.0 0.066 11.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBY35839.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family U-box PF04564.15 CBY35840.1 - 7.6e-09 35.6 0.0 1.9e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 U-box domain Pkinase PF00069.25 CBY35842.1 - 2e-41 142.1 0.0 2.5e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY35842.1 - 6.7e-14 51.8 0.0 1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY35842.1 - 1.1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY35842.1 - 3.2e-06 26.7 0.0 5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY35842.1 - 1.6e-05 23.9 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY35842.1 - 0.0011 19.0 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY35842.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CBY35842.1 - 0.035 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GreA_GreB_N PF03449.15 CBY35843.1 - 0.0094 16.1 2.3 0.03 14.5 2.3 2.0 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal KxDL PF10241.9 CBY35843.1 - 0.014 15.7 3.2 0.014 15.7 3.2 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein CREPT PF16566.5 CBY35843.1 - 0.07 13.3 6.1 0.12 12.6 5.4 1.8 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Cep57_CLD PF14073.6 CBY35843.1 - 0.072 13.1 11.4 0.15 12.1 11.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Occludin_ELL PF07303.13 CBY35843.1 - 5.1 7.9 19.9 0.18 12.5 2.8 3.9 2 1 2 4 4 4 0 Occludin homology domain Peptidase_M2 PF01401.18 CBY35844.1 - 1e-42 146.6 0.0 1.7e-42 145.8 0.0 1.3 1 1 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M2 PF01401.18 CBY35845.1 - 3e-33 115.3 0.0 3.6e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme sCache_2 PF17200.4 CBY35845.1 - 0.16 11.8 0.1 0.39 10.6 0.1 1.6 2 0 0 2 2 2 0 Single Cache domain 2 Arcadin_1 PF18653.1 CBY35846.1 - 0.021 14.9 0.2 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Arcadin 1 CpeT PF06206.11 CBY35846.1 - 0.09 12.7 1.3 1.8 8.5 0.2 2.3 2 0 0 2 2 2 0 CpeT/CpcT family (DUF1001) DUF192 PF02643.15 CBY35846.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 PIP5K PF01504.18 CBY35848.1 - 3.9e-84 282.1 0.2 5.4e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MCU PF04678.13 CBY35849.1 - 1.8e-49 168.2 0.8 4.6e-49 166.9 0.8 1.8 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Thg1C PF14413.6 CBY35849.1 - 2.3e-40 137.6 2.9 2.5e-40 137.4 0.9 2.2 2 0 0 2 2 2 1 Thg1 C terminal domain Thg1 PF04446.12 CBY35849.1 - 2.2e-25 89.1 0.0 7.5e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Phospholip_A2_1 PF00068.19 CBY35849.1 - 2.3e-18 66.7 8.1 8.2e-18 64.9 8.1 2.0 1 0 0 1 1 1 1 Phospholipase A2 LPD37 PF18853.1 CBY35850.1 - 0.0075 15.8 0.1 0.013 15.1 0.0 1.4 2 0 0 2 2 2 1 Large polyvalent protein associated domain 37 DUF4230 PF14014.6 CBY35850.1 - 0.16 12.2 1.4 0.21 11.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Mucin PF01456.17 CBY35851.1 - 0.71 9.9 16.2 1.4 8.9 16.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein TSP_1 PF00090.19 CBY35853.1 - 6.8e-113 368.8 365.6 4.2e-11 42.9 1.6 29.1 27 2 1 28 28 28 26 Thrombospondin type 1 domain PTR2 PF00854.21 CBY35854.1 - 8e-96 321.3 15.2 9.9e-81 271.6 9.7 2.2 2 0 0 2 2 2 2 POT family Oxidored_q2 PF00420.24 CBY35854.1 - 0.29 10.8 0.1 0.29 10.8 0.1 3.0 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L wnt PF00110.19 CBY35855.1 - 1.7e-33 116.5 20.7 4.7e-32 111.8 20.7 2.0 1 1 0 1 1 1 1 wnt family Fer4_24 PF18109.1 CBY35856.1 - 3.8e-08 33.5 0.0 4.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin I 4Fe-4S cluster domain HalX PF08663.10 CBY35856.1 - 0.029 14.7 0.2 0.44 10.9 0.0 2.0 1 1 1 2 2 2 0 HalX domain HSBP1 PF06825.12 CBY35856.1 - 0.05 13.5 0.1 3.2 7.7 0.0 2.2 1 1 1 2 2 2 0 Heat shock factor binding protein 1 WASH_WAHD PF11945.8 CBY35856.1 - 0.052 13.1 0.4 0.061 12.9 0.4 1.0 1 0 0 1 1 1 0 WAHD domain of WASH complex DUF501 PF04417.12 CBY35856.1 - 0.073 12.9 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF501) MtrG PF04210.13 CBY35856.1 - 0.1 12.4 0.3 4.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G PKD_channel PF08016.12 CBY35857.1 - 3.5e-136 454.3 7.3 5.6e-136 453.6 7.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY35857.1 - 4.5e-24 85.0 21.8 4.5e-24 85.0 21.8 1.7 2 0 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.32 CBY35857.1 - 0.00085 18.7 1.5 0.033 13.7 0.3 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY35857.1 - 0.031 14.2 3.0 0.23 11.5 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain Abhydrolase_9_N PF15420.6 CBY35857.1 - 0.14 12.1 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Kelch_1 PF01344.25 CBY35858.1 - 2.2e-11 43.1 5.7 0.00092 18.7 0.0 5.9 7 1 0 7 7 7 3 Kelch motif Kelch_4 PF13418.6 CBY35858.1 - 4.7e-11 42.5 1.9 0.56 10.3 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY35858.1 - 9.6e-09 35.3 0.0 0.13 12.6 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY35858.1 - 7.3e-07 29.3 4.3 0.15 12.4 0.0 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.6 CBY35858.1 - 2.1e-06 27.6 2.4 1.4 8.9 0.0 5.6 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY35858.1 - 1.5e-05 24.8 0.2 0.31 11.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif CbiD PF01888.17 CBY35858.1 - 0.22 10.8 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 CbiD TSNAXIP1_N PF15739.5 CBY35859.1 - 0.031 14.6 6.0 0.027 14.9 3.9 2.0 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus AlkA_N PF06029.11 CBY35859.1 - 0.12 12.7 0.2 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 AlkA N-terminal domain PikAIV_N PF18605.1 CBY35859.1 - 1.3 8.7 3.9 0.76 9.4 0.9 2.2 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF525 PF04379.14 CBY35860.1 - 0.011 15.9 0.2 6.1 7.2 0.0 2.8 3 0 0 3 3 3 0 ApaG domain HeH PF12949.7 CBY35861.1 - 6e-06 25.9 0.2 3.3e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 HeH/LEM domain TMIE PF16038.5 CBY35861.1 - 4 7.3 5.6 58 3.6 4.5 3.1 2 0 0 2 2 2 0 TMIE protein Period_C PF12114.8 CBY35862.1 - 0.0048 16.5 0.8 0.0048 16.5 0.8 1.4 2 0 0 2 2 2 1 Period protein 2/3C-terminal region ABC_tran PF00005.27 CBY35863.1 - 3e-12 47.2 0.0 3.1e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY35863.1 - 0.00026 21.0 0.1 0.00026 20.9 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CBY35863.1 - 0.0005 20.6 0.1 0.0005 20.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBY35863.1 - 0.00073 19.3 0.0 0.00074 19.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CBY35863.1 - 0.0008 19.3 0.1 0.0008 19.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY35863.1 - 0.0015 18.2 0.4 0.0019 17.9 0.4 1.4 1 1 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 CBY35863.1 - 0.0019 18.1 0.2 0.0019 18.1 0.2 1.1 1 0 0 1 1 1 1 MukB N-terminal AAA_30 PF13604.6 CBY35863.1 - 0.0031 17.3 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 CBY35863.1 - 0.0031 17.1 0.0 0.0039 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBY35863.1 - 0.0048 17.0 0.2 0.0055 16.8 0.2 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBY35863.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.1 1 0 0 1 1 1 0 AIG1 family DLIC PF05783.11 CBY35863.1 - 0.05 12.4 0.0 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SMC_N PF02463.19 CBY35863.1 - 0.057 12.9 0.1 0.057 12.8 0.1 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CBY35863.1 - 0.076 13.4 0.1 0.083 13.3 0.1 1.1 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 CBY35863.1 - 0.082 12.5 0.4 0.086 12.5 0.4 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBY35863.1 - 0.083 12.4 0.1 0.088 12.3 0.1 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBY35863.1 - 0.11 12.8 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBY35863.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_13 PF13166.6 CBY35863.1 - 0.16 10.6 0.1 0.16 10.6 0.1 1.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY35863.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY35863.1 - 0.26 11.5 0.3 0.27 11.5 0.3 1.1 1 0 0 1 1 1 0 AAA domain PLAC8 PF04749.17 CBY35864.1 - 4.5e-08 34.0 35.5 6.7e-08 33.5 35.5 1.3 1 0 0 1 1 1 1 PLAC8 family Sulfotransfer_1 PF00685.27 CBY35865.1 - 4.4e-13 49.3 0.0 6.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY35865.1 - 2e-05 25.1 0.0 0.00095 19.6 0.0 2.9 1 1 0 1 1 1 1 Sulfotransferase family GST_N PF02798.20 CBY35866.1 - 2.2e-06 27.9 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CBY35866.1 - 0.0018 19.0 0.0 0.0034 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 CBY35866.1 - 0.051 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY35866.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RA PF00788.23 CBY35867.1 - 0.0012 19.4 0.0 0.0049 17.5 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain CCDC-167 PF15188.6 CBY35867.1 - 6.7 7.1 7.9 7.1 7.0 3.9 3.0 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 UCH PF00443.29 CBY35868.1 - 7.1e-72 242.0 0.5 1.5e-71 240.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CBY35868.1 - 2.1e-12 47.5 3.0 2.1e-12 47.5 3.0 2.9 2 2 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CBY35868.1 - 1.7e-09 37.8 2.5 0.00052 19.7 0.0 3.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 CBY35868.1 - 0.00056 19.9 0.1 0.0017 18.3 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain USP7_C2 PF14533.6 CBY35868.1 - 0.0073 16.0 0.7 0.016 14.9 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-ribbon_3 PF13248.6 CBY35868.1 - 0.056 12.9 4.4 0.53 9.8 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBY35868.1 - 0.33 11.0 2.0 24 5.0 0.1 2.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBY35868.1 - 0.43 10.7 3.1 24 5.1 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Ribosomal_S27e PF01667.17 CBY35868.1 - 0.48 10.2 3.4 4.5 7.0 0.6 2.8 2 0 0 2 2 2 0 Ribosomal protein S27 Taxilin PF09728.9 CBY35869.1 - 8.4e-74 248.5 51.9 1.4e-73 247.8 51.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF3584 PF12128.8 CBY35869.1 - 5.8 4.3 51.7 0.21 9.1 32.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Mce4_CUP1 PF11887.8 CBY35869.1 - 8 5.8 10.3 2.1 7.7 1.2 3.4 2 2 2 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative RE_AlwI PF09491.10 CBY35871.1 - 0.0089 14.9 4.1 0.01 14.6 4.1 1.0 1 0 0 1 1 1 1 AlwI restriction endonuclease Complex1_51K PF01512.17 CBY35871.1 - 0.11 12.3 0.2 8 6.3 0.0 2.1 1 1 1 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit DUF2570 PF10828.8 CBY35871.1 - 0.46 10.3 6.2 0.13 12.1 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) ABC_tran PF00005.27 CBY35872.1 - 8.6e-52 175.3 0.0 5.1e-28 98.3 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY35872.1 - 5.5e-42 144.1 60.0 9.8e-37 126.8 20.5 2.7 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY35872.1 - 4.1e-10 40.0 0.0 2.7e-06 27.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY35872.1 - 0.00012 22.6 5.4 0.013 16.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.22 CBY35872.1 - 0.00053 19.7 0.6 1.1 8.8 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SMC_N PF02463.19 CBY35872.1 - 0.0042 16.6 0.0 2 7.8 0.0 3.4 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY35872.1 - 0.0055 16.6 0.5 0.17 11.8 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 CBY35872.1 - 0.0062 16.3 0.6 0.4 10.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBY35872.1 - 0.029 14.6 0.1 15 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CBY35872.1 - 0.03 14.0 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CBY35872.1 - 0.034 14.0 0.9 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF4162 PF13732.6 CBY35873.1 - 0.14 12.9 0.1 0.18 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) LAMTOR5 PF16672.5 CBY35874.1 - 7.7e-05 22.6 0.0 9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Serpin PF00079.20 CBY35875.1 - 3.1e-37 128.7 0.0 7.2e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) ETC_C1_NDUFA5 PF04716.14 CBY35876.1 - 2e-12 46.7 0.1 3.5e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region MARVEL PF01284.23 CBY35877.1 - 3.1e-15 56.5 10.0 5.7e-15 55.6 10.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain PTPA PF03095.15 CBY35878.1 - 2.6e-104 348.9 0.0 2.9e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2203 PF09969.9 CBY35878.1 - 0.038 14.7 0.0 0.069 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) NIF PF03031.18 CBY35879.1 - 1.2e-26 93.3 0.2 2.1e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 CBY35879.1 - 6.8e-07 28.9 0.1 1.2e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Mito_carr PF00153.27 CBY35880.1 - 1.4e-53 178.8 1.3 5.8e-19 67.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIR2 PF02146.17 CBY35881.1 - 5.6e-56 189.3 0.0 7.7e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family SH3_9 PF14604.6 CBY35882.1 - 2.4e-06 27.3 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY35882.1 - 8.9e-05 22.0 0.6 0.00022 20.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain PBP_N PF17093.5 CBY35883.1 - 0.042 14.1 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus BTB PF00651.31 CBY35885.1 - 0.00095 19.4 0.0 0.002 18.3 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain Ldh_1_N PF00056.23 CBY35886.1 - 1.4e-07 31.7 0.1 2.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBY35886.1 - 0.0054 16.7 0.0 0.034 14.1 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sugar-bind PF04198.13 CBY35886.1 - 0.075 12.1 0.1 0.6 9.2 0.0 2.2 2 1 0 2 2 2 0 Putative sugar-binding domain Pkinase_Tyr PF07714.17 CBY35888.1 - 0.0011 18.3 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY35888.1 - 0.043 13.2 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Sulfotransfer_2 PF03567.14 CBY35889.1 - 1.1e-07 32.1 1.7 4.1e-07 30.2 0.9 2.1 2 0 0 2 2 2 1 Sulfotransferase family YBD PF17725.1 CBY35890.1 - 3.2e-25 89.2 0.1 4.3e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CBY35890.1 - 2.4e-06 27.5 2.5 8.3e-06 25.8 2.1 2.2 2 0 0 2 2 2 1 TEA/ATTS domain EMP24_GP25L PF01105.24 CBY35891.1 - 1.1e-44 152.6 0.0 1.3e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Phlebovirus_NSM PF07246.11 CBY35891.1 - 0.06 12.7 0.1 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M GST_N_3 PF13417.6 CBY35892.1 - 5.2e-11 42.8 0.0 6.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY35892.1 - 1.2e-07 31.9 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY35892.1 - 7.7e-07 29.4 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BicD PF09730.9 CBY35893.1 - 1.7e-96 324.3 77.9 1.8e-67 228.3 19.3 3.6 1 1 2 3 3 3 3 Microtubule-associated protein Bicaudal-D Mce4_CUP1 PF11887.8 CBY35893.1 - 0.11 12.0 1.8 0.3 10.5 1.8 1.8 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative ZnuA PF01297.17 CBY35893.1 - 9 5.6 15.8 0.069 12.5 1.2 3.0 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic ApoO PF09769.9 CBY35893.1 - 9.9 6.1 9.2 0.71 9.8 0.3 3.4 3 1 0 4 4 4 0 Apolipoprotein O Y_phosphatase PF00102.27 CBY35894.1 - 3.4e-64 216.6 1.6 3.8e-64 216.5 1.6 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBY35894.1 - 2.6e-05 24.4 0.0 4.3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 CBY35894.1 - 0.00028 20.7 0.1 0.00057 19.7 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY35894.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family OTU PF02338.19 CBY35895.1 - 6.3e-24 84.9 1.0 1.8e-23 83.4 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease AIF-MLS PF14962.6 CBY35895.1 - 2.4 8.1 10.4 2.3 8.2 9.1 1.6 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Draxin PF15550.6 CBY35895.1 - 3 7.6 11.6 3.8 7.3 11.6 1.2 1 0 0 1 1 1 0 Draxin Ndc1_Nup PF09531.10 CBY35895.1 - 4.1 6.0 4.9 4.7 5.8 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Thioredoxin PF00085.20 CBY35896.1 - 5.2e-64 212.7 0.1 3.2e-31 107.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY35896.1 - 8.4e-40 136.6 0.0 3.2e-35 121.7 0.1 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY35896.1 - 2.2e-09 37.8 0.1 0.0055 17.1 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY35896.1 - 9.9e-09 35.3 0.0 0.0027 17.8 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY35896.1 - 2.1e-07 30.9 1.0 0.032 14.1 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY35896.1 - 8.3e-07 29.2 0.0 0.054 13.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY35896.1 - 1.1e-06 28.2 0.0 0.065 12.6 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CBY35896.1 - 0.00034 20.3 1.4 1.5 8.5 0.0 3.8 4 0 0 4 4 4 1 Redoxin Thioredoxin_4 PF13462.6 CBY35896.1 - 0.0078 16.4 0.1 0.63 10.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 CBY35896.1 - 0.092 12.4 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin HyaE PF07449.11 CBY35896.1 - 0.12 12.4 0.3 23 5.0 0.0 3.6 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE TMEM132D_C PF15706.5 CBY35897.1 - 0.1 12.4 0.2 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TNFR_16_TM PF18422.1 CBY35898.1 - 0.15 12.0 0.8 0.22 11.5 0.8 1.2 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain OATP PF03137.20 CBY35899.1 - 1.2e-99 334.1 11.3 1.4e-99 333.8 11.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY35899.1 - 1.7e-17 63.4 16.3 1.3e-14 54.0 10.8 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CBY35900.1 - 1e-36 124.2 21.3 2.3e-06 28.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35900.1 - 2.8e-11 43.5 0.1 0.0023 18.2 0.1 4.7 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF3668 PF12416.8 CBY35901.1 - 7.5e-19 68.4 1.2 2.9e-17 63.2 0.0 3.6 3 2 0 3 3 3 1 Cep120 protein DUF4497 PF14924.6 CBY35901.1 - 0.011 16.2 0.1 0.12 12.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) C2 PF00168.30 CBY35901.1 - 0.046 14.0 0.0 15 5.9 0.0 3.0 2 1 0 2 2 2 0 C2 domain NT-C2 PF10358.9 CBY35901.1 - 0.061 13.1 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4537 PF15057.6 CBY35902.1 - 1.4e-56 189.7 2.2 9.3e-30 103.1 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY35902.1 - 7.9e-06 25.6 0.0 1.9 8.4 0.0 4.2 4 0 0 4 4 4 2 DNA repair protein Crb2 Tudor domain DUF4819 PF16090.5 CBY35902.1 - 0.0015 18.6 0.5 19 5.4 0.0 4.0 2 2 2 4 4 4 2 Domain of unknown function (DUF4819) Tudor_2 PF18104.1 CBY35902.1 - 0.0076 15.9 0.5 1.2 8.9 0.0 4.4 5 0 0 5 5 5 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 CBY35902.1 - 0.051 13.3 0.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 Tox-ODYAM1 PF15642.6 CBY35903.1 - 0.069 12.1 9.3 0.08 11.9 9.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Tugs PF17840.1 CBY35903.1 - 0.78 10.0 4.4 6 7.1 0.5 2.4 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain TMPIT PF07851.13 CBY35903.1 - 1.7 7.8 8.9 1.9 7.7 8.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4570 PF15134.6 CBY35903.1 - 3.8 7.6 14.7 5.4 7.1 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) EF-hand_7 PF13499.6 CBY35905.1 - 5.7e-17 61.9 7.9 1.9e-08 34.6 3.6 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY35905.1 - 7.8e-17 59.5 16.6 1.7e-08 33.4 1.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY35905.1 - 9.1e-15 54.2 11.4 3.9e-09 36.2 0.1 3.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBY35905.1 - 3.8e-12 45.1 10.0 0.00036 20.2 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 CBY35905.1 - 5.6e-06 26.6 0.8 0.028 14.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY35905.1 - 4.1e-05 23.5 8.2 0.00049 20.0 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CBY35905.1 - 0.00017 21.0 11.9 0.0024 17.3 0.2 4.4 4 0 0 4 4 4 2 EF hand TerB PF05099.13 CBY35905.1 - 0.034 14.1 0.5 3.2 7.7 0.0 2.5 1 1 1 3 3 3 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 CBY35905.1 - 0.26 11.6 4.4 2.8 8.3 1.9 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GST_C_3 PF14497.6 CBY35906.1 - 1.5e-10 41.1 0.0 1.7e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY35906.1 - 7.4e-07 29.3 0.0 1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY35906.1 - 4.5e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5600 PF18150.1 CBY35906.1 - 0.055 14.1 0.0 0.078 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) PsiF_repeat PF07769.14 CBY35906.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 psiF repeat ORC2 PF04084.14 CBY35907.1 - 1.2e-39 136.2 1.1 1.4e-39 135.9 1.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 WGG PF10273.9 CBY35908.1 - 1.7e-14 54.2 0.1 3.6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3381 PF11861.8 CBY35908.1 - 0.025 14.4 2.2 0.044 13.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PRMT5_TIM PF17285.2 CBY35908.1 - 0.099 11.8 0.6 0.88 8.7 0.1 2.1 2 0 0 2 2 2 0 PRMT5 TIM barrel domain Acetyltransf_1 PF00583.25 CBY35909.1 - 9.5e-14 51.6 0.1 1.2e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY35909.1 - 7.1e-11 42.1 0.2 9.8e-11 41.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY35909.1 - 1.6e-09 38.1 0.1 2.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY35909.1 - 0.00027 21.1 0.1 0.00035 20.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF22 PF01629.16 CBY35909.1 - 0.016 14.9 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF22 FR47 PF08445.10 CBY35909.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CBY35909.1 - 0.052 13.7 0.1 0.12 12.5 0.1 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Inositol_P PF00459.25 CBY35910.1 - 1.2e-72 244.8 0.0 1.3e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family eIF2A PF08662.11 CBY35911.1 - 1.7e-18 67.2 0.0 3.6e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CBY35911.1 - 0.013 15.8 0.0 0.073 13.4 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBY35911.1 - 0.11 11.5 0.0 6.2 5.7 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region RRM_1 PF00076.22 CBY35912.1 - 2.3e-05 24.1 0.1 6.9e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CBY35912.1 - 0.026 15.4 4.8 11 7.1 0.1 4.0 3 1 1 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY35912.1 - 0.034 14.5 0.0 0.84 10.0 0.0 2.8 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Flavodoxin_1 PF00258.25 CBY35913.1 - 9.3e-11 42.1 0.1 1.9e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CBY35913.1 - 0.0027 17.3 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain LIFR_N PF18207.1 CBY35913.1 - 0.061 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain PRKCSH-like PF12999.7 CBY35914.1 - 7.5e-28 97.5 7.4 1.2e-27 96.8 7.4 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.18 CBY35914.1 - 0.25 11.6 19.3 0.45 10.8 5.8 2.4 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A RIIa PF02197.17 CBY35915.1 - 0.00097 18.8 0.2 0.0025 17.4 0.1 1.8 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit MucBP_2 PF17965.1 CBY35916.1 - 0.42 11.2 3.2 1.4 9.5 0.8 2.2 2 0 0 2 2 2 0 Mucin binding domain Rtt106 PF08512.12 CBY35917.1 - 4.8e-18 65.4 0.0 6.7e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SURF2 PF05477.11 CBY35917.1 - 4.1 7.0 21.6 5.2 6.7 21.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 CBY35917.1 - 4.8 5.3 22.9 5.4 5.1 22.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CBY35917.1 - 9.9 4.3 21.8 12 4.0 21.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_49 PF13896.6 CBY35918.1 - 7.1e-75 252.4 0.0 8.9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan SH3BGR PF04908.15 CBY35919.1 - 2.2e-20 72.6 0.0 2.7e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CBY35919.1 - 0.041 14.1 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin ABC_tran_Xtn PF12848.7 CBY35919.1 - 0.15 12.1 0.1 5.9 7.0 0.1 2.3 2 0 0 2 2 2 0 ABC transporter Ephrin_rec_like PF07699.13 CBY35920.1 - 0.0015 18.3 17.7 0.0019 17.9 2.7 53.0 35 15 16 55 55 55 30 Putative ephrin-receptor like 7tm_1 PF00001.21 CBY35921.1 - 0.12 11.7 1.2 0.15 11.3 1.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zinc_ribbon_10 PF10058.9 CBY35922.1 - 6.4e-17 61.0 0.2 1.3e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein MRI PF15325.6 CBY35922.1 - 0.2 12.8 9.6 0.65 11.1 9.6 1.9 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF2048 PF09752.9 CBY35923.1 - 1.2e-68 231.8 0.0 1.4e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Sigma70_r4_2 PF08281.12 CBY35923.1 - 0.00093 18.8 0.1 0.0095 15.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Lipase_3 PF01764.25 CBY35923.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 CBY35923.1 - 0.13 12.2 0.2 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC_tran_CTD PF16326.5 CBY35924.1 - 0.016 15.5 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain MIF4G PF02854.19 CBY35925.1 - 7.1e-07 29.1 0.4 1.7e-06 27.9 0.4 1.7 1 1 0 1 1 1 1 MIF4G domain GHMP_kinases_C PF08544.13 CBY35926.1 - 3.7e-08 33.6 0.1 1e-07 32.2 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.7 CBY35926.1 - 0.052 13.4 0.2 0.068 13.0 0.2 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term GalKase_gal_bdg PF10509.9 CBY35927.1 - 0.0065 16.0 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Galactokinase galactose-binding signature zf-C4pol PF14260.6 CBY35928.1 - 7.6e-16 58.3 10.0 1.1e-15 57.9 10.0 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B PF00136.21 CBY35928.1 - 8e-12 44.6 0.0 1.6e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B DZR PF12773.7 CBY35928.1 - 0.016 15.3 9.6 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 CBY35928.1 - 0.27 11.2 10.9 0.97 9.4 2.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 CBY35928.1 - 0.34 10.9 15.5 1.3 9.0 7.5 2.2 1 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 CBY35928.1 - 0.86 9.6 12.3 1.1 9.3 1.0 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHY PF05495.12 CBY35928.1 - 4.1 7.9 14.1 4.7 7.8 0.8 2.2 1 1 1 2 2 2 0 CHY zinc finger DNA_pol_B PF00136.21 CBY35929.1 - 5.2e-117 391.4 0.2 7.1e-117 390.9 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBY35929.1 - 1e-84 284.6 0.4 1.3e-84 284.2 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 CBY35929.1 - 0.00019 20.4 0.3 0.0011 18.0 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF4309 PF14172.6 CBY35929.1 - 0.096 12.7 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) THF_DHG_CYH_C PF02882.19 CBY35930.1 - 2.9e-38 130.7 0.0 4.4e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY35930.1 - 6.8e-32 110.2 0.0 9.2e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain HEAT PF02985.22 CBY35931.1 - 3.6e-12 45.4 4.6 0.00099 19.2 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 CBY35931.1 - 3.6e-11 43.3 0.1 1.2e-05 25.6 0.0 4.2 4 0 0 4 4 3 2 HEAT repeats Cnd1 PF12717.7 CBY35931.1 - 1e-10 41.9 0.0 1.3e-05 25.3 0.1 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CBY35931.1 - 2.1e-09 37.3 0.0 0.016 14.8 0.0 4.2 3 1 1 4 4 4 3 CLASP N terminal HEAT_EZ PF13513.6 CBY35931.1 - 3.9e-06 27.2 6.1 0.013 16.0 0.1 6.5 6 1 1 7 7 7 2 HEAT-like repeat Importin_rep_6 PF18829.1 CBY35931.1 - 0.00012 22.1 0.2 0.00045 20.3 0.2 2.0 1 0 0 1 1 1 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 CBY35931.1 - 0.0004 20.9 0.0 0.095 13.3 0.0 3.9 4 1 1 5 5 4 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CBY35931.1 - 0.0016 18.4 0.1 0.21 11.5 0.0 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CBY35931.1 - 0.0026 16.9 0.3 0.031 13.4 0.2 2.4 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 CBY35931.1 - 0.037 13.1 0.1 3.2 6.8 0.0 3.7 4 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 CBY35931.1 - 0.047 13.4 0.1 2.9 7.6 0.0 3.0 2 2 1 3 3 3 0 rRNA processing/ribosome biogenesis TFCD_C PF12612.8 CBY35931.1 - 0.17 11.7 0.1 3.7 7.3 0.0 3.0 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal PBP1_TM PF14812.6 CBY35931.1 - 4.5 7.7 9.3 0.23 11.8 2.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 CBY35934.1 - 2.8e-20 72.5 22.9 3.8e-20 72.1 22.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY35934.1 - 2.8e-09 36.8 10.5 1.5e-06 27.8 5.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4233 PF14017.6 CBY35934.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4233) SARAF PF06682.12 CBY35935.1 - 1.9e-70 238.2 24.5 3.4e-59 201.1 0.2 2.0 1 1 1 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis Sortilin-Vps10 PF15902.5 CBY35936.1 - 1.7e-107 360.0 5.1 3e-107 359.2 5.1 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CBY35936.1 - 9.3e-36 123.7 10.2 2e-35 122.6 10.2 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CBY35936.1 - 1.9e-05 24.0 24.3 9.7 6.7 0.1 9.5 9 0 0 9 9 9 2 BNR/Asp-box repeat BNR_2 PF13088.6 CBY35936.1 - 0.00059 19.2 3.2 0.16 11.2 0.3 4.2 2 1 2 4 4 4 1 BNR repeat-like domain BNR_6 PF15899.5 CBY35936.1 - 2.8 8.3 13.0 50 4.4 0.0 5.9 6 0 0 6 6 6 0 BNR-Asp box repeat Helicase_C PF00271.31 CBY35937.1 - 2.5e-14 53.6 0.0 9.4e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CBY35937.1 - 3.2e-14 53.1 0.0 3.2e-14 53.1 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY35937.1 - 4.4e-11 43.0 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CBY35937.1 - 4.8e-09 36.2 0.1 1.9e-08 34.2 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY35937.1 - 5.9e-05 23.4 1.0 0.00063 20.0 1.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBY35937.1 - 0.015 15.6 0.2 0.047 14.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY35937.1 - 0.057 12.5 0.0 0.42 9.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 CBY35937.1 - 0.15 12.1 6.5 0.056 13.5 0.5 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF2721 PF11026.8 CBY35938.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Membrane_bind PF14564.6 CBY35938.1 - 0.4 11.1 3.1 5 7.6 0.1 3.0 2 1 1 3 3 3 0 Membrane binding Ras PF00071.22 CBY35939.1 - 3.4e-44 150.3 0.2 3.8e-44 150.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY35939.1 - 5.8e-18 65.3 0.0 7.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY35939.1 - 8.3e-13 48.2 0.0 9.4e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY35939.1 - 3.1e-06 27.2 1.6 0.0057 16.6 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY35939.1 - 4.4e-05 23.1 0.1 0.00011 21.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CBY35939.1 - 0.0023 17.9 0.2 0.0056 16.7 0.2 1.6 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CBY35939.1 - 0.045 13.3 0.1 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B CbiA PF01656.23 CBY35939.1 - 0.056 13.5 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 CBY35939.1 - 0.082 13.3 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ParA PF10609.9 CBY35939.1 - 0.1 12.1 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase RicinB_lectin_2 PF14200.6 CBY35942.1 - 1.2e-11 45.1 1.1 9.5e-05 23.1 0.5 2.0 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CBY35942.1 - 5.6e-08 33.1 0.0 8.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3341 PF11821.8 CBY35943.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) AP_endonuc_2 PF01261.24 CBY35943.1 - 0.063 12.7 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2225 PF09986.9 CBY35943.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) AP_endonuc_2 PF01261.24 CBY35944.1 - 3.9e-20 72.2 0.0 7.9e-20 71.2 0.0 1.4 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_1 PF00036.32 CBY35944.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CBY35944.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Trypsin PF00089.26 CBY35946.1 - 9.6e-05 22.3 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY35947.1 - 2.3e-16 60.3 0.3 3.9e-16 59.5 0.2 1.4 1 1 0 1 1 1 1 Trypsin DUF3668 PF12416.8 CBY35947.1 - 0.012 15.4 0.2 0.019 14.8 0.2 1.2 1 0 0 1 1 1 0 Cep120 protein Homeodomain PF00046.29 CBY35948.1 - 1.3e-20 73.0 0.6 1.3e-20 73.0 0.6 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY35948.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Myosin_head PF00063.21 CBY35949.1 - 4.2e-261 868.0 0.1 1.5e-260 866.2 0.1 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY35949.1 - 3.5e-96 323.2 200.8 2.5e-64 217.7 125.6 4.2 1 1 2 3 3 3 3 Myosin tail Myosin_N PF02736.19 CBY35949.1 - 0.0091 15.8 1.3 0.03 14.2 1.3 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBY35949.1 - 0.093 13.0 6.1 0.36 11.1 0.0 4.5 3 0 0 3 3 3 0 AAA domain IQ PF00612.27 CBY35949.1 - 0.097 12.5 0.2 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_16 PF13191.6 CBY35949.1 - 1.6 9.1 0.0 1.6 9.1 0.0 5.7 2 1 0 2 2 2 0 AAA ATPase domain SEA PF01390.20 CBY35950.1 - 0.12 12.4 16.8 0.25 11.5 0.1 4.3 4 1 0 4 4 4 0 SEA domain F5_F8_type_C PF00754.25 CBY35951.1 - 5.4e-06 26.5 0.1 0.00016 21.8 0.1 2.1 1 1 0 1 1 1 1 F5/8 type C domain ELFV_dehydrog_N PF02812.18 CBY35953.1 - 3e-56 188.8 0.0 5.2e-56 188.1 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 CBY35953.1 - 5.3e-43 147.5 0.1 3e-41 141.8 0.1 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CENP-F_N PF10481.9 CBY35953.1 - 0.077 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain O-FucT PF10250.9 CBY35954.1 - 4e-06 26.8 0.0 8.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_M2 PF01401.18 CBY35955.1 - 6.1e-207 688.7 5.7 7.2e-207 688.5 5.7 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme PKcGMP_CC PF16808.5 CBY35955.1 - 0.0011 18.7 1.1 0.0024 17.7 1.1 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 CBY35955.1 - 0.019 15.6 0.7 0.049 14.2 0.7 1.6 1 0 0 1 1 1 0 SlyX Fib_alpha PF08702.10 CBY35955.1 - 0.021 15.0 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5517 PF17639.2 CBY35956.1 - 0.0055 17.0 1.6 0.0069 16.7 1.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5517) MFS_1 PF07690.16 CBY35958.1 - 2.5e-05 23.4 2.2 3.1e-05 23.1 2.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CRAM_rpt PF07016.11 CBY35959.1 - 3.2 7.7 6.8 2.5 8.0 0.7 2.4 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor Forkhead PF00250.18 CBY35960.1 - 1e-38 131.4 0.1 1.4e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Forkhead domain RRM_1 PF00076.22 CBY35961.1 - 3.1e-15 55.7 0.0 5.5e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DBB PF14545.6 CBY35961.1 - 0.0039 17.1 0.1 0.0074 16.2 0.1 1.5 1 1 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, IFP_35_N PF07334.13 CBY35961.1 - 0.099 12.7 1.6 0.17 12.0 1.6 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GBP_C PF02841.14 CBY35961.1 - 0.17 11.3 6.2 0.22 10.9 6.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4140 PF13600.6 CBY35961.1 - 1.4 9.4 4.8 2.7 8.5 4.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FoP_duplication PF13865.6 CBY35961.1 - 8.7 7.0 7.7 20 5.8 7.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TLD PF07534.16 CBY35962.1 - 1.8e-31 109.2 0.3 2.7e-31 108.7 0.3 1.3 1 0 0 1 1 1 1 TLD GRAM PF02893.20 CBY35962.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 GRAM domain LysM PF01476.20 CBY35965.1 - 4.2e-06 26.7 0.0 5.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 LysM domain Nucleos_tra2_C PF07662.13 CBY35966.1 - 8.3e-62 208.7 1.7 8.3e-62 208.7 1.7 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CBY35966.1 - 4.5e-12 46.4 8.9 2.4e-11 44.0 8.9 2.4 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY35966.1 - 1.1e-05 25.7 6.0 1.1e-05 25.7 6.0 3.7 5 0 0 5 5 5 1 Nucleoside recognition Gal-3-0_sulfotr PF06990.11 CBY35968.1 - 8.4e-17 61.1 0.6 1.3e-16 60.5 0.6 1.3 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase BBP1_C PF15272.6 CBY35968.1 - 0.078 12.8 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Nuc_sug_transp PF04142.15 CBY35969.1 - 3.7e-23 82.2 16.2 1.1e-22 80.7 16.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY35969.1 - 0.0065 16.7 6.4 0.0065 16.7 6.4 2.2 1 1 0 2 2 2 1 EamA-like transporter family Phage_holin_3_3 PF16083.5 CBY35969.1 - 0.045 13.9 0.3 0.13 12.4 0.3 1.8 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Ldl_recept_a PF00057.18 CBY35970.1 - 0.00015 21.9 9.9 0.00015 21.9 9.9 4.0 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.24 CBY35971.1 - 4.2e-49 166.4 0.0 5.5e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 CBY35971.1 - 0.00068 18.3 0.1 0.00091 17.9 0.1 1.1 1 0 0 1 1 1 1 Putative peptidase family Astacin PF01400.24 CBY35971.1 - 0.0012 18.5 0.2 0.18 11.4 0.1 2.2 2 0 0 2 2 2 2 Astacin (Peptidase family M12A) DUF4953 PF16313.5 CBY35971.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 CBY35971.1 - 0.018 14.0 0.1 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 CBY35971.1 - 0.022 14.4 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CBY35971.1 - 0.058 13.5 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY35971.1 - 0.058 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.11 CBY35971.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M7 PF02031.16 CBY35971.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.5 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Transcrip_act PF04949.13 CBY35972.1 - 0.057 13.3 7.1 0.067 13.1 7.1 1.0 1 0 0 1 1 1 0 Transcriptional activator Phage_Mu_Gam PF07352.12 CBY35972.1 - 0.39 10.6 7.5 0.78 9.6 7.3 1.6 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Astacin PF01400.24 CBY35973.1 - 3.2e-09 36.7 1.3 4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY35973.1 - 1.3e-05 25.3 6.0 1.3e-05 25.3 6.0 4.0 4 0 0 4 4 4 2 Calcium-binding EGF domain UPF0054 PF02130.17 CBY35973.1 - 0.2 11.5 0.5 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 RRM_1 PF00076.22 CBY35974.1 - 1.7e-36 123.8 0.0 5e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY35974.1 - 0.00021 20.9 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY35974.1 - 0.021 14.9 0.0 9.2 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RNA_bind PF08675.11 CBY35974.1 - 0.025 14.6 0.0 2.3 8.3 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain EF-hand_7 PF13499.6 CBY35975.1 - 7.6e-11 42.3 8.5 2.7e-08 34.1 2.6 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY35975.1 - 3.2e-09 35.7 5.4 0.00014 21.2 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY35975.1 - 6.8e-09 35.0 5.1 1.6e-05 24.4 0.6 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY35975.1 - 8.5e-05 21.9 4.8 0.00025 20.4 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CBY35975.1 - 0.0042 16.9 13.6 0.013 15.3 2.5 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CBY35975.1 - 0.012 15.9 0.2 0.65 10.4 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain U3_assoc_6 PF08640.11 CBY35975.1 - 0.018 15.1 1.7 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 PTS_2-RNA PF01885.16 CBY35975.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Caleosin PF05042.13 CBY35975.1 - 0.063 13.2 1.0 0.8 9.6 0.0 2.6 2 1 1 3 3 3 0 Caleosin related protein Peptidase_C24 PF03510.14 CBY35976.1 - 0.055 14.0 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family Mitofilin PF09731.9 CBY35977.1 - 0.13 11.0 17.3 0.16 10.8 17.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mpp10 PF04006.12 CBY35977.1 - 0.25 9.8 19.9 0.32 9.4 19.9 1.1 1 0 0 1 1 1 0 Mpp10 protein API5 PF05918.11 CBY35977.1 - 0.3 9.9 11.7 0.37 9.5 11.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RR_TM4-6 PF06459.12 CBY35977.1 - 3.1 7.6 14.5 4.2 7.1 14.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CBY35977.1 - 3.8 6.3 21.6 4.8 6.0 21.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Voltage_CLC PF00654.20 CBY35978.1 - 2.2e-94 316.6 20.6 2.2e-94 316.6 20.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBY35978.1 - 3.9e-14 52.8 0.2 3.7e-08 33.7 0.0 3.3 3 0 0 3 3 3 2 CBS domain p450 PF00067.22 CBY35979.1 - 1.2e-57 195.7 0.8 1.5e-57 195.4 0.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 L_lactis_RepB_C PF06430.12 CBY35979.1 - 0.044 13.8 0.7 0.096 12.7 0.2 1.7 2 1 0 2 2 2 0 Lactococcus lactis RepB C-terminus Sulfotransfer_4 PF17784.1 CBY35980.1 - 8.5e-37 127.1 1.0 1.3e-36 126.5 1.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY35980.1 - 0.0012 19.3 0.3 0.0084 16.5 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Baculo_p74_N PF08404.10 CBY35981.1 - 0.00069 18.8 0.0 0.00081 18.6 0.0 1.1 1 0 0 1 1 1 1 Baculoviridae P74 N-terminal Mcl1_mid PF12341.8 CBY35982.1 - 6e-47 160.4 0.0 6.6e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region zf-C2H2 PF00096.26 CBY35983.1 - 0.00095 19.5 2.6 0.00095 19.5 2.6 6.3 6 1 0 6 6 6 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY35983.1 - 0.0083 15.9 12.1 0.052 13.3 3.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY35983.1 - 0.02 15.7 1.5 0.02 15.7 1.5 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBY35983.1 - 0.21 11.3 0.1 0.21 11.3 0.1 5.0 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CBY35983.1 - 0.25 11.8 23.3 1.9 9.0 0.8 5.1 5 0 0 5 5 5 0 Zinc-finger double domain AlbA_2 PF04326.14 CBY35984.1 - 2e-11 44.3 0.0 5e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Putative DNA-binding domain 4HBT PF03061.22 CBY35986.1 - 4.1e-06 27.1 0.0 6.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CBY35986.1 - 0.067 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Acatn PF13000.7 CBY35987.1 - 1.4e-77 261.5 19.7 2.2e-64 217.9 14.2 2.9 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 DUF3860 PF12976.7 CBY35990.1 - 0.18 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) C2-set_2 PF08205.12 CBY35992.1 - 0.0082 16.2 0.2 1.3 9.1 0.1 2.4 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY35992.1 - 0.017 15.7 0.3 0.22 12.2 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Synapsin PF02078.16 CBY35992.1 - 0.18 12.1 0.1 1.6 9.0 0.0 2.3 2 1 0 2 2 2 0 Synapsin, N-terminal domain Transcrip_act PF04949.13 CBY35993.1 - 4.9e-08 33.0 24.5 4.9e-08 33.0 24.5 2.8 1 1 1 2 2 2 1 Transcriptional activator zf-RING_2 PF13639.6 CBY35994.1 - 2.3e-09 37.5 8.1 2.3e-09 37.5 8.1 3.1 5 0 0 5 5 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY35994.1 - 5.4e-07 29.2 4.8 2.4e-06 27.1 3.5 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY35994.1 - 4.9e-06 26.3 7.4 4.9e-06 26.3 7.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY35994.1 - 0.00016 21.6 7.4 0.00016 21.6 7.4 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY35994.1 - 0.00096 19.0 7.8 0.00096 19.0 7.8 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY35994.1 - 0.0033 17.7 9.9 0.0033 17.7 9.9 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C2HC_2 PF13913.6 CBY35994.1 - 0.0038 17.1 2.1 0.094 12.6 0.3 2.9 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-WRNIP1_ubi PF18279.1 CBY35994.1 - 0.016 15.8 1.3 12 6.8 0.0 3.0 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain RINGv PF12906.7 CBY35994.1 - 0.094 12.9 4.9 0.34 11.1 4.9 2.0 1 1 0 1 1 1 0 RING-variant domain zf-met2 PF12907.7 CBY35994.1 - 0.16 12.1 1.5 7.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding zf-Nse PF11789.8 CBY35994.1 - 0.18 11.7 4.0 0.17 11.8 2.1 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CBY35994.1 - 0.8 9.8 11.4 1.4 9.1 4.3 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 CBY35994.1 - 2.3 8.4 10.4 6 7.1 1.5 2.8 2 1 0 2 2 2 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 CBY35994.1 - 2.8 7.6 9.1 0.21 11.2 3.4 2.1 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-C2H2_4 PF13894.6 CBY35994.1 - 3.3 8.8 8.2 1.2 10.1 0.2 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY35994.1 - 4.7 7.9 9.7 1.1 9.9 0.1 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type FANCL_C PF11793.8 CBY35994.1 - 5.1 7.3 9.9 12 6.2 4.4 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CBY35994.1 - 5.7 6.9 18.0 0.39 10.6 4.4 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) tRNA_bind_2 PF13725.6 CBY35996.1 - 2.1e-09 37.4 0.4 2.9e-09 37.0 0.4 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain GNAT_acetyltr_2 PF13718.6 CBY35996.1 - 2.9e-06 26.8 0.1 3.7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Ubiquitin_4 PF18036.1 CBY35996.1 - 0.094 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain ENOD40 PF08247.11 CBY35996.1 - 0.43 10.7 1.5 0.59 10.2 0.1 1.9 2 0 0 2 2 2 0 ENOD40 protein tRNA_bind_2 PF13725.6 CBY35997.1 - 5.1e-34 118.0 4.4 7.4e-34 117.5 4.4 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Ly49 PF08391.10 CBY35997.1 - 0.22 11.9 1.5 0.52 10.7 1.5 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Cobl PF09469.10 CBY35997.1 - 0.35 11.2 2.7 7.8 6.8 0.1 2.7 2 1 0 2 2 2 0 Cordon-bleu ubiquitin-like domain tRNA_Me_trans PF03054.16 CBY35998.1 - 1.1e-59 202.0 0.2 2.1e-59 201.1 0.2 1.4 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CBY35998.1 - 8.1e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 CBY35998.1 - 0.0015 18.2 0.0 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CBY35998.1 - 0.0018 17.8 0.0 0.09 12.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 CBY35998.1 - 0.0032 16.6 0.0 0.0072 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 CBY35998.1 - 0.52 10.0 4.4 0.77 9.5 1.0 2.8 2 1 0 2 2 2 0 PP-loop family tRNA_Me_trans PF03054.16 CBY35999.1 - 0.00029 19.7 0.0 0.00039 19.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase Mito_carr PF00153.27 CBY36000.1 - 1.1e-51 172.7 0.7 1.4e-23 82.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CcmD PF04995.14 CBY36001.1 - 0.002 18.2 0.2 0.0031 17.6 0.2 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF3482 PF11981.8 CBY36001.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) CH PF00307.31 CBY36003.1 - 1.3e-37 128.3 0.3 3.5e-20 72.2 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain Spectrin PF00435.21 CBY36003.1 - 6.3e-20 71.6 38.8 2.4e-10 40.8 0.7 5.6 4 1 1 5 5 5 4 Spectrin repeat CAMSAP_CH PF11971.8 CBY36003.1 - 4.5e-12 45.6 0.0 3e-07 30.2 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 CBY36003.1 - 0.0087 16.2 1.1 0.18 12.0 0.1 3.1 3 0 0 3 3 3 1 CH-like domain in sperm protein Glyco_transf_4 PF13439.6 CBY36003.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Allexi_40kDa PF05549.11 CBY36003.1 - 8.7 5.8 12.2 2.2 7.7 3.9 2.9 2 1 0 3 3 3 0 Allexivirus 40kDa protein DUF4059 PF13268.6 CBY36004.1 - 0.061 13.7 2.2 0.061 13.7 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) DUF3644 PF12358.8 CBY36005.1 - 0.7 10.4 2.4 1.1 9.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) Sec34 PF04136.15 CBY36006.1 - 0.011 15.6 0.8 1.4 8.8 0.0 3.0 2 2 1 3 3 3 0 Sec34-like family CAMP_factor PF07373.11 CBY36006.1 - 0.072 12.7 0.4 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 CAMP factor (Cfa) DUF4927 PF16279.5 CBY36006.1 - 0.085 13.9 0.6 0.18 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4927) BLYB PF05289.11 CBY36006.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.1 2 1 0 2 2 2 0 Borrelia hemolysin accessory protein Cortex-I_coil PF09304.10 CBY36006.1 - 1 9.6 6.9 0.96 9.7 0.1 2.9 2 1 0 3 3 3 0 Cortexillin I, coiled coil Borrelia_P83 PF05262.11 CBY36007.1 - 0.062 11.8 20.8 0.08 11.4 20.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.6 CBY36007.1 - 7.4 7.1 13.2 12 6.4 13.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF148 PF02520.17 CBY36008.1 - 0.005 16.9 0.2 0.16 12.1 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF148 DUF3734 PF12536.8 CBY36008.1 - 0.1 12.9 0.1 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Patatin phospholipase Abhydrolase_6 PF12697.7 CBY36010.1 - 3.4e-11 44.2 0.0 4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY36010.1 - 1.5e-10 41.2 0.1 2e-10 40.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY36010.1 - 7.2e-08 32.0 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CBY36010.1 - 0.0046 17.1 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PRP38 PF03371.15 CBY36011.1 - 1.4e-56 191.1 0.0 1.8e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Steroid_dh PF02544.16 CBY36012.1 - 1.4e-51 174.4 1.6 2.8e-51 173.5 1.6 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBY36012.1 - 6.5e-05 22.6 0.3 0.00011 21.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 CBY36013.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Phostensin PF13914.6 CBY36013.1 - 0.068 13.8 1.1 0.09 13.4 1.0 1.4 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Pkinase PF00069.25 CBY36014.1 - 8.4e-32 110.6 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36014.1 - 8.6e-23 80.9 0.0 1.2e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36014.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBY36014.1 - 0.0025 16.9 0.1 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CBY36014.1 - 0.007 15.4 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain zf-AN1 PF01428.16 CBY36016.1 - 3.9e-10 39.7 7.4 5.7e-10 39.2 7.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger FTHFS PF01268.19 CBY36017.1 - 2.9e-261 867.5 0.1 2.9e-261 867.5 0.1 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CBY36017.1 - 8.4e-64 213.7 0.3 8.4e-64 213.7 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY36017.1 - 1e-33 116.1 0.6 2e-33 115.1 0.6 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_47 PF01532.20 CBY36018.1 - 1.3e-120 403.4 0.0 1.3e-120 403.4 0.0 2.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 47 Trypsin PF00089.26 CBY36019.1 - 2.4e-28 99.4 0.0 3.8e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin VWA PF00092.28 CBY36019.1 - 0.00029 21.1 1.1 0.00064 20.0 0.4 1.9 1 1 1 2 2 2 1 von Willebrand factor type A domain TMEM154 PF15102.6 CBY36019.1 - 0.011 15.6 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family VWA_2 PF13519.6 CBY36019.1 - 0.021 15.4 0.0 0.097 13.3 0.0 2.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase PF00069.25 CBY36020.1 - 4.9e-08 32.7 0.0 7.7e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36020.1 - 0.0051 16.1 0.2 0.011 15.1 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase AA_permease_2 PF13520.6 CBY36021.1 - 1.4e-53 182.3 39.7 1.6e-53 182.1 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY36021.1 - 7.7e-19 67.6 36.0 2.5e-18 66.0 36.3 1.6 1 1 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 CBY36022.1 - 7.2e-23 79.7 47.8 4.1e-07 30.1 3.5 6.0 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY36022.1 - 3.3e-21 74.1 38.7 0.0001 22.8 2.1 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY36022.1 - 1.8e-19 69.2 36.3 3e-07 30.6 3.9 6.7 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY36022.1 - 3e-10 40.1 21.3 0.0029 17.8 0.8 5.3 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY36022.1 - 3.9e-09 36.6 25.6 0.003 17.9 1.9 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY36022.1 - 1.2e-08 34.8 29.1 0.00037 20.4 2.1 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-BED PF02892.15 CBY36022.1 - 4.6e-06 26.5 23.5 0.0026 17.7 3.2 5.2 3 1 2 5 5 5 2 BED zinc finger zf-C2H2_2 PF12756.7 CBY36022.1 - 0.00013 22.3 22.4 0.55 10.6 0.8 4.9 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 CBY36022.1 - 0.00049 20.2 15.8 2 8.6 0.3 5.5 5 0 0 5 5 5 1 AN1-like Zinc finger Prok-RING_1 PF14446.6 CBY36022.1 - 0.0019 18.1 11.6 11 6.0 0.1 5.4 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 CBY36022.1 - 0.0026 18.0 5.1 0.0026 18.0 5.1 4.6 3 1 1 5 5 4 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CBY36022.1 - 0.0049 17.0 11.7 1.5 9.0 0.3 4.5 3 1 1 4 4 4 1 Zinc ribbon domain Zf_RING PF16744.5 CBY36022.1 - 0.0089 16.1 18.3 3 8.0 0.2 5.4 2 1 3 5 5 5 2 KIAA1045 RING finger Elf1 PF05129.13 CBY36022.1 - 0.013 15.5 17.7 0.14 12.2 1.6 4.4 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like GAGA PF09237.11 CBY36022.1 - 0.014 15.2 14.7 2 8.3 0.6 4.2 2 2 2 4 4 4 0 GAGA factor Yippee-Mis18 PF03226.14 CBY36022.1 - 0.017 15.3 10.1 0.038 14.2 1.9 3.0 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-H2C2_5 PF13909.6 CBY36022.1 - 0.043 13.6 23.1 1.4 8.8 1.5 5.7 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Rad50_zn_hook PF04423.14 CBY36022.1 - 0.055 13.3 0.2 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_15 PF17032.5 CBY36022.1 - 0.088 13.6 14.6 1.3 9.8 0.8 3.7 2 1 0 3 3 2 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 CBY36022.1 - 0.18 11.5 0.0 0.18 11.5 0.0 4.0 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-CHCC PF10276.9 CBY36022.1 - 0.27 11.3 5.4 5.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger domain Zn-C2H2_12 PF18112.1 CBY36022.1 - 0.4 11.2 17.9 2.6 8.6 0.2 5.4 5 1 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 CBY36022.1 - 0.47 10.4 11.0 3.9 7.4 0.1 4.5 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) HNH_5 PF14279.6 CBY36022.1 - 0.54 10.2 12.4 26 4.8 0.8 5.1 4 2 1 5 5 5 0 HNH endonuclease zf-C2H2_3rep PF18868.1 CBY36022.1 - 0.68 10.6 22.5 1.1e+03 0.2 18.8 4.8 2 1 0 2 2 1 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 CBY36022.1 - 0.71 9.8 21.5 6.2 6.8 0.6 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 CBY36022.1 - 1.3 8.7 12.2 20 4.9 0.2 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger FYVE PF01363.21 CBY36022.1 - 2.3 8.4 28.9 0.24 11.6 9.0 4.0 3 1 1 4 4 3 0 FYVE zinc finger zf_ZIC PF18366.1 CBY36022.1 - 2.4 8.3 20.1 1.4 9.1 0.5 5.1 2 1 3 5 5 5 0 Zic proteins zinc finger domain zf-C4_ClpX PF06689.13 CBY36022.1 - 3.3 7.7 8.7 7.5 6.5 0.2 3.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger LIM PF00412.22 CBY36022.1 - 3.6 7.9 17.4 16 5.8 0.6 4.7 2 1 1 4 4 4 0 LIM domain XPA_N PF01286.18 CBY36022.1 - 5.5 7.1 16.9 13 5.9 0.1 5.1 5 0 0 5 5 5 0 XPA protein N-terminal zf-UBR PF02207.20 CBY36023.1 - 0.05 13.8 5.4 0.093 12.9 5.4 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-CHY PF05495.12 CBY36023.1 - 0.31 11.5 5.5 0.69 10.4 5.5 1.7 1 1 0 1 1 1 0 CHY zinc finger Ank_4 PF13637.6 CBY36024.1 - 9.4e-10 38.8 0.1 1e-05 26.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY36024.1 - 2.8e-06 27.5 0.1 0.077 13.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY36024.1 - 0.0002 21.9 0.0 0.066 13.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) CHGN PF05679.16 CBY36025.1 - 1.1e-55 189.5 12.9 2.5e-37 128.9 0.8 2.4 3 0 0 3 3 3 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY36025.1 - 4.1e-16 59.2 0.2 3.6e-15 56.1 0.1 2.4 2 1 0 2 2 2 1 Fringe-like Glyco_transf_7C PF02709.14 CBY36025.1 - 9.8e-10 38.0 0.5 2.5e-09 36.7 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_2 PF00535.26 CBY36025.1 - 0.00017 21.4 0.2 0.082 12.7 0.1 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 2 Galactosyl_T PF01762.21 CBY36025.1 - 0.00033 20.5 0.0 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Galactosyltransferase Glyco_transf_21 PF13506.6 CBY36025.1 - 0.091 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Pro_isomerase PF00160.21 CBY36026.1 - 1.3e-41 142.5 0.0 1.5e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Miff PF05644.11 CBY36027.1 - 0.0037 16.9 1.8 0.0072 16.0 0.5 1.8 1 1 1 2 2 2 1 Mitochondrial and peroxisomal fission factor Mff Pkinase PF00069.25 CBY36028.1 - 1.1e-34 120.0 0.0 1.6e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36028.1 - 2.7e-28 99.0 0.0 4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY36028.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY36028.1 - 0.072 12.4 0.0 0.27 10.5 0.0 1.7 1 1 1 2 2 2 0 Kinase-like MyTH4 PF00784.17 CBY36029.1 - 2.5e-59 198.5 0.1 2.5e-30 105.2 0.0 3.1 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 CBY36029.1 - 1.1e-27 96.7 0.2 5.2e-17 62.3 0.0 3.9 4 0 0 4 4 4 2 FERM central domain FERM_N PF09379.10 CBY36029.1 - 1.8e-11 43.8 0.9 2.2e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 FERM N-terminal domain Myosin_head PF00063.21 CBY36029.1 - 2.3e-09 36.1 0.1 2.3e-09 36.1 0.1 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) IQ PF00612.27 CBY36029.1 - 2.3e-07 30.0 31.1 0.00021 20.8 5.1 6.1 6 0 0 6 6 6 3 IQ calmodulin-binding motif PID PF00640.23 CBY36029.1 - 0.014 15.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) Myosin_head PF00063.21 CBY36030.1 - 1e-37 129.8 0.1 1.1e-37 129.6 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Gal-3-0_sulfotr PF06990.11 CBY36031.1 - 1.6e-18 66.8 0.1 2.1e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase HnRNPA1 PF11627.8 CBY36031.1 - 0.024 14.8 0.4 0.024 14.8 0.4 2.3 3 0 0 3 3 3 0 Nuclear factor hnRNPA1 SET PF00856.28 CBY36033.1 - 5.2e-09 36.7 0.1 6.4e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 SET domain PI-PLC-X PF00388.19 CBY36034.1 - 6e-33 113.5 0.1 1.1e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY36034.1 - 1.7e-13 50.9 0.0 4.3e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CBY36034.1 - 3.2e-13 50.0 0.0 7.7e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 CBY36034.1 - 1.9e-12 47.8 0.0 4.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY36034.1 - 0.00076 20.0 0.2 0.0028 18.1 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_14 PF17787.1 CBY36034.1 - 0.0014 18.4 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 CBY36034.1 - 0.0018 18.7 0.1 0.01 16.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair Mcp5_PH PF12814.7 CBY36034.1 - 0.004 17.3 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology EF-hand_1 PF00036.32 CBY36034.1 - 0.018 14.6 0.1 0.04 13.5 0.1 1.7 1 0 0 1 1 1 0 EF hand C2 PF00168.30 CBY36035.1 - 2.4e-13 50.2 0.0 5.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain PI-PLC-Y PF00387.19 CBY36035.1 - 3.1e-05 24.3 0.0 9.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain IQ PF00612.27 CBY36036.1 - 0.24 11.3 8.7 2.7 8.0 0.1 3.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif KIP1 PF07765.12 CBY36037.1 - 0.025 14.7 0.1 0.075 13.2 0.1 1.7 1 0 0 1 1 1 0 KIP1-like protein 2OG-FeII_Oxy_3 PF13640.6 CBY36038.1 - 1.4e-07 32.3 0.0 2.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Anp1 PF03452.14 CBY36038.1 - 0.017 14.6 0.1 8.2 5.8 0.0 3.0 2 1 1 3 3 3 0 Anp1 Glyco_trans_A_1 PF09318.10 CBY36038.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A Tetraspanin PF00335.20 CBY36039.1 - 1.4e-09 38.0 15.9 3.2e-08 33.6 15.9 2.2 1 1 0 1 1 1 1 Tetraspanin family Herpes_UL1 PF05259.11 CBY36039.1 - 0.062 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Cation_ATPase_C PF00689.21 CBY36039.1 - 0.41 10.3 6.5 0.069 12.9 2.4 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.9 CBY36039.1 - 3.5 6.3 8.5 1.7 7.4 5.3 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) PH PF00169.29 CBY36040.1 - 9.6e-07 29.3 0.2 1.3e-06 28.9 0.2 1.2 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 CBY36041.1 - 2.3e-20 73.6 0.1 2.3e-20 73.6 0.1 2.0 2 1 0 2 2 2 1 RhoGEF domain SR-25 PF10500.9 CBY36041.1 - 8.7 5.9 15.1 15 5.1 15.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ASH PF15780.5 CBY36043.1 - 6e-08 32.8 2.8 0.0002 21.5 0.2 4.0 3 1 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY36043.1 - 9e-07 28.7 5.9 0.21 11.4 0.0 3.8 3 0 0 3 3 3 3 MSP (Major sperm protein) domain PapD-like PF14874.6 CBY36043.1 - 0.0039 17.3 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 2 Flagellar-associated PapD-like fn3_5 PF06280.12 CBY36043.1 - 0.0051 17.5 3.0 0.15 12.7 0.2 3.3 3 0 0 3 3 3 1 Fn3-like domain DUF1573 PF07610.11 CBY36043.1 - 0.01 15.9 4.2 6.5 6.9 0.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1573) Prenyltrans PF00432.21 CBY36044.1 - 0.0035 17.1 0.7 0.0094 15.7 0.7 1.9 1 1 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat SET PF00856.28 CBY36045.1 - 5.1e-06 27.0 0.1 3.4e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 SET domain LPD37 PF18853.1 CBY36047.1 - 0.0071 15.9 0.1 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 Large polyvalent protein associated domain 37 DUF4230 PF14014.6 CBY36047.1 - 0.092 13.0 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Phospholip_A2_1 PF00068.19 CBY36048.1 - 2.4e-18 66.6 8.0 2.4e-18 66.6 8.0 2.3 3 0 0 3 3 3 1 Phospholipase A2 MCU PF04678.13 CBY36049.1 - 3.5e-51 173.8 0.6 5.2e-51 173.2 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Hpt PF01627.23 CBY36049.1 - 0.054 13.7 1.5 0.083 13.2 0.1 2.0 2 0 0 2 2 2 0 Hpt domain Mod_r PF07200.13 CBY36049.1 - 1.7 8.7 8.2 0.13 12.3 2.4 1.9 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Thg1 PF04446.12 CBY36050.1 - 1.2e-41 141.7 0.0 2.4e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CBY36050.1 - 1.2e-40 138.4 1.8 1.2e-40 138.4 1.8 1.8 2 0 0 2 2 2 1 Thg1 C terminal domain cNMP_binding PF00027.29 CBY36051.1 - 2.2e-36 123.8 0.2 3.6e-18 65.4 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CBY36051.1 - 2.5e-11 43.0 0.0 5.8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit fragilysinNterm PF16376.5 CBY36051.1 - 0.033 13.9 1.1 2.7 7.7 0.2 2.4 1 1 1 2 2 2 0 N-terminal domain of fragilysin KIND PF16474.5 CBY36051.1 - 0.067 13.1 2.3 0.14 12.1 2.3 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Peptidase_C15 PF01470.17 CBY36052.1 - 0.0096 16.1 0.1 0.029 14.5 0.1 1.8 1 1 0 1 1 1 1 Pyroglutamyl peptidase GP3 PF03076.14 CBY36052.1 - 0.037 14.1 0.2 0.047 13.7 0.2 1.1 1 0 0 1 1 1 0 Equine arteritis virus GP3 B-block_TFIIIC PF04182.12 CBY36052.1 - 0.054 13.7 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC NTP_transferase PF00483.23 CBY36053.1 - 0.00077 19.1 0.0 0.0008 19.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CBY36053.1 - 0.022 15.1 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 MobA-like NTP transferase domain GHMP_kinases_N PF00288.26 CBY36054.1 - 5.8e-07 29.7 0.0 1.6e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBY36054.1 - 1.4e-05 25.3 0.1 2.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transferase PF00483.23 CBY36054.1 - 0.00087 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase RRM_1 PF00076.22 CBY36055.1 - 3.5e-19 68.4 0.0 7.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coilin_N PF15862.5 CBY36055.1 - 0.023 14.5 3.7 0.13 12.1 0.2 2.1 2 0 0 2 2 2 0 Coilin N-terminus GlcNAc-1_reg PF18440.1 CBY36055.1 - 0.17 12.1 0.3 23 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain PET117 PF15786.5 CBY36055.1 - 5.9 7.2 8.1 7.1 7.0 1.6 2.3 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial Ank_2 PF12796.7 CBY36056.1 - 2.6e-72 239.4 29.4 5e-17 62.3 0.5 7.3 5 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY36056.1 - 2.1e-63 209.9 30.1 4e-11 43.2 0.1 11.6 6 3 7 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 CBY36056.1 - 4.6e-59 194.4 32.3 5.1e-07 29.9 0.2 14.3 14 1 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 CBY36056.1 - 1.8e-58 193.8 28.1 5.8e-10 39.2 0.2 11.7 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY36056.1 - 4.5e-52 167.9 25.5 0.00011 22.3 0.0 15.7 17 0 0 17 17 17 11 Ankyrin repeat Ank_2 PF12796.7 CBY36057.1 - 2e-22 79.6 2.3 6.2e-07 29.9 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY36057.1 - 2.3e-22 78.8 0.4 3.8e-05 23.9 0.0 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY36057.1 - 1.4e-16 60.6 1.9 0.0011 19.6 0.0 6.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY36057.1 - 2.1e-14 52.2 0.2 0.034 14.7 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CBY36057.1 - 1.6e-12 47.3 0.2 0.0021 18.4 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat AIRS PF00586.24 CBY36057.1 - 0.096 13.4 0.0 0.38 11.4 0.0 2.0 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain IMPDH PF00478.25 CBY36058.1 - 0.02 13.9 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IMPDH PF00478.25 CBY36059.1 - 8.5e-96 320.9 2.4 1.1e-95 320.6 2.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBY36059.1 - 1.6e-11 44.5 0.1 1.1e-07 32.2 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CBY36059.1 - 6.2e-08 32.4 0.1 3e-06 26.9 0.2 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 CBY36059.1 - 8.1e-06 25.4 0.2 2.6e-05 23.8 0.2 1.7 1 1 1 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 CBY36059.1 - 5.3e-05 22.4 1.0 8.8e-05 21.7 1.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 CBY36059.1 - 0.0018 17.6 0.3 0.0033 16.8 0.3 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 CBY36059.1 - 0.051 12.8 0.4 0.19 10.9 0.1 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF1525 PF07511.11 CBY36060.1 - 0.42 10.8 1.8 1.3 9.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) SCAN PF02023.17 CBY36060.1 - 0.72 9.7 4.7 9.6 6.1 0.2 2.9 3 0 0 3 3 3 0 SCAN domain SAM_2 PF07647.17 CBY36061.1 - 2.3e-34 117.3 3.0 3.4e-14 52.7 0.1 4.1 4 0 0 4 4 4 3 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY36061.1 - 7.1e-30 103.3 2.6 1.4e-16 60.6 0.1 4.1 3 1 0 3 3 3 3 SAM domain (Sterile alpha motif) TPR_2 PF07719.17 CBY36063.1 - 8.5e-15 53.6 7.3 0.00015 21.6 0.0 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36063.1 - 1.9e-14 52.6 0.7 0.00026 21.0 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY36063.1 - 2.4e-12 47.2 3.1 0.0027 18.2 0.0 5.2 4 3 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY36063.1 - 1.3e-10 40.7 1.8 0.0046 16.7 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36063.1 - 6.6e-10 39.5 3.3 0.001 19.7 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36063.1 - 4.2e-09 36.6 6.6 4.4e-05 23.7 0.0 4.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36063.1 - 1e-08 34.9 0.7 0.015 15.7 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36063.1 - 7.8e-08 32.5 11.8 1.4 9.9 0.0 7.3 2 2 5 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 CBY36063.1 - 3.5e-07 30.1 3.6 0.015 15.0 0.0 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 CBY36063.1 - 4.4e-07 29.5 0.0 0.019 14.6 0.0 3.5 3 0 0 3 3 3 2 TPR repeat ANAPC3 PF12895.7 CBY36063.1 - 1.5e-05 25.1 0.9 0.2 11.9 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBY36063.1 - 2.6e-05 23.9 1.3 0.029 14.4 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY36063.1 - 0.0052 16.2 1.0 0.08 12.3 0.1 2.7 2 1 1 3 3 3 1 MalT-like TPR region TPR_3 PF07720.12 CBY36063.1 - 0.012 15.6 0.0 5.6 7.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 CBY36063.1 - 0.016 14.2 0.0 4 6.2 0.0 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBY36063.1 - 0.029 15.0 4.8 38 5.2 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY36063.1 - 0.041 13.8 1.2 4.7 7.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CBY36063.1 - 0.066 12.6 0.1 0.68 9.3 0.0 2.5 1 1 1 2 2 2 0 Coatomer epsilon subunit Lectin_C PF00059.21 CBY36066.1 - 0.04 14.6 0.0 12 6.7 0.0 2.5 1 1 0 2 2 2 0 Lectin C-type domain zf-C2H2 PF00096.26 CBY36067.1 - 7.8e-06 26.1 12.6 0.017 15.5 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY36067.1 - 0.00078 19.8 2.2 0.00078 19.8 2.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY36067.1 - 0.032 15.1 1.9 0.032 15.1 1.9 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger DPBB_1 PF03330.18 CBY36067.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Zona_pellucida PF00100.23 CBY36068.1 - 1e-31 110.7 2.1 1e-31 110.7 2.1 2.0 3 0 0 3 3 3 1 Zona pellucida-like domain Beta_helix PF13229.6 CBY36068.1 - 0.00011 22.2 6.4 0.0013 18.6 2.3 3.1 2 0 0 2 2 2 1 Right handed beta helix region G8 PF10162.9 CBY36068.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 G8 domain SpoIIID PF12116.8 CBY36068.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D MOZ_SAS PF01853.18 CBY36069.1 - 1.1e-79 266.3 0.1 2.3e-79 265.2 0.1 1.6 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY36069.1 - 1e-22 79.4 6.1 1.5e-22 79.0 4.0 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY36069.1 - 6.1e-13 48.4 0.7 1.4e-12 47.3 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBY36069.1 - 0.001 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY36069.1 - 0.026 14.8 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.24 CBY36069.1 - 0.03 14.2 0.6 0.084 12.8 0.6 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF724 PF05266.14 CBY36069.1 - 3.7 7.3 6.8 5.3 6.8 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GTP_EFTU PF00009.27 CBY36071.1 - 2e-50 171.1 0.1 2.9e-50 170.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY36071.1 - 2.5e-14 53.1 0.0 5.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CBY36071.1 - 0.00039 20.5 0.3 0.0012 18.9 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CBY36071.1 - 0.0043 16.9 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Arf PF00025.21 CBY36071.1 - 0.11 11.9 0.3 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family EFG_C PF00679.24 CBY36072.1 - 2.9e-05 24.0 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBY36072.1 - 0.039 13.7 0.4 0.66 9.8 0.4 2.1 1 1 0 1 1 1 0 Elongation factor G, domain IV Asn_synthase PF00733.21 CBY36073.1 - 2.7e-23 83.2 0.0 3.4e-20 73.0 0.0 2.2 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CBY36073.1 - 3.4e-13 49.6 0.0 9e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBY36073.1 - 1.2e-08 35.2 0.0 8.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain CBM_X2 PF03442.14 CBY36073.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Peptidase_M18 PF02127.15 CBY36074.1 - 4.9e-89 299.1 0.0 5.6e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBY36074.1 - 0.049 12.6 0.1 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Sulfotransfer_1 PF00685.27 CBY36075.1 - 0.00066 19.2 0.6 0.0049 16.4 0.6 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36075.1 - 0.005 17.3 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family IQ PF00612.27 CBY36076.1 - 0.0028 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ PF00612.27 CBY36077.1 - 5.1e-21 72.4 0.1 1.8e-05 24.1 0.0 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif RIIa PF02197.17 CBY36077.1 - 6e-09 35.4 0.2 1.1e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Gemini_mov PF01708.16 CBY36079.1 - 0.11 12.3 0.6 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein MORN PF02493.20 CBY36080.1 - 3.3e-36 121.0 59.4 2e-06 27.3 1.7 8.9 8 0 0 8 8 8 8 MORN repeat Cas_Cas1 PF01867.16 CBY36080.1 - 0.42 9.7 2.5 0.63 9.1 2.5 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF3619 PF12279.8 CBY36080.1 - 0.48 10.8 3.4 0.74 10.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4398 PF14346.6 CBY36080.1 - 2.1 9.0 15.1 1.4 9.6 8.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) EGF_CA PF07645.15 CBY36082.1 - 9.5e-08 32.1 3.2 9.5e-08 32.1 3.2 3.3 2 1 1 3 3 3 1 Calcium-binding EGF domain SSP160 PF06933.11 CBY36082.1 - 0.034 12.4 12.9 0.045 12.0 12.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 CBY36082.1 - 0.044 13.7 11.4 0.077 13.0 11.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.11 CBY36082.1 - 0.64 10.0 4.9 0.99 9.3 4.9 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.12 CBY36082.1 - 1.7 6.5 4.3 2.2 6.2 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2964 PF11177.8 CBY36083.1 - 0.055 13.7 0.9 0.28 11.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) CTP_transf_like PF01467.26 CBY36084.1 - 1.4e-19 70.7 0.0 1.9e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF525 PF04379.14 CBY36085.1 - 8.6e-24 83.6 0.0 1.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 CBY36085.1 - 0.00061 20.2 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Profilin PF00235.19 CBY36086.1 - 3e-10 40.5 0.0 3.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Profilin UPF0242 PF06785.11 CBY36088.1 - 0.00075 19.7 7.8 0.00075 19.7 7.8 3.2 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Trypsin PF00089.26 CBY36089.1 - 4.7e-55 186.8 0.2 4.7e-55 186.8 0.2 2.1 3 0 0 3 3 3 1 Trypsin Na_H_Exchanger PF00999.21 CBY36090.1 - 2.9e-30 105.3 3.5 3.7e-30 105.0 3.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MRP-S28 PF10213.9 CBY36090.1 - 0.041 14.3 0.1 0.079 13.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein DUF4145 PF13643.6 CBY36090.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Homeodomain PF00046.29 CBY36091.1 - 3.7e-25 87.5 2.2 3.7e-25 87.5 2.2 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY36091.1 - 0.00042 20.2 0.4 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 Homeobox KN domain MRP-L20 PF12824.7 CBY36091.1 - 0.00054 20.2 2.0 0.00077 19.7 2.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Kelch_1 PF01344.25 CBY36092.1 - 5.4e-10 38.7 0.7 1.1e-06 28.1 0.0 2.3 2 1 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY36092.1 - 1.4e-08 34.7 0.9 5.9e-06 26.4 0.1 2.2 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CBY36092.1 - 4.5e-07 29.6 0.3 0.019 15.0 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY36092.1 - 0.00026 20.9 1.3 0.027 14.5 0.1 2.4 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY36092.1 - 0.0069 16.4 0.3 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 CBY36092.1 - 0.015 15.6 0.3 0.034 14.4 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Thyroglobulin_1 PF00086.18 CBY36093.1 - 2.2e-07 30.4 2.5 2.2e-07 30.4 2.5 1.8 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat PAN_1 PF00024.26 CBY36093.1 - 3.3e-07 30.2 1.5 3.3e-07 30.2 1.5 2.0 2 0 0 2 2 2 1 PAN domain WD40 PF00400.32 CBY36095.1 - 2.5e-20 72.4 13.7 9.2e-07 29.5 0.0 7.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36095.1 - 8.7e-12 45.2 1.7 0.072 13.4 0.2 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain EIAV_GP90 PF00971.18 CBY36095.1 - 0.1 11.3 0.1 0.22 10.2 0.1 1.5 1 0 0 1 1 1 0 EIAV coat protein, gp90 Bromodomain PF00439.25 CBY36096.1 - 5.3e-08 32.8 0.7 1.3e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 Bromodomain CUB PF00431.20 CBY36097.1 - 3.5e-14 53.1 0.0 5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 CUB domain LIM PF00412.22 CBY36098.1 - 1e-32 112.1 59.9 6.5e-09 35.9 8.2 4.2 4 0 0 4 4 4 4 LIM domain Auto_anti-p27 PF06677.12 CBY36099.1 - 0.024 14.8 1.5 0.14 12.3 2.0 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GGN PF15685.5 CBY36099.1 - 0.38 9.8 0.2 0.4 9.7 0.2 1.0 1 0 0 1 1 1 0 Gametogenetin Trypsin PF00089.26 CBY36100.1 - 1.6e-23 83.7 0.1 2.5e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY36100.1 - 0.07 14.0 0.0 0.13 13.1 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain DUF620 PF04788.12 CBY36100.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) VWC PF00093.18 CBY36100.1 - 0.28 11.5 5.1 0.28 11.5 2.3 2.5 1 1 1 2 2 2 0 von Willebrand factor type C domain DUF5453 PF17534.2 CBY36101.1 - 0.074 13.0 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Mucin PF01456.17 CBY36102.1 - 0.00018 21.5 18.0 0.00026 21.0 18.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CDC27 PF09507.10 CBY36102.1 - 0.00031 20.3 7.9 0.00039 19.9 7.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Cas_TM1802 PF09484.10 CBY36102.1 - 0.0067 15.2 4.0 0.0094 14.8 4.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein TM1802 (cas_TM1802) SID-1_RNA_chan PF13965.6 CBY36102.1 - 0.54 8.6 3.2 0.64 8.4 3.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ASD2 PF08687.11 CBY36102.1 - 0.96 8.9 9.8 1.9 8.0 9.8 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 DUF2116 PF09889.9 CBY36102.1 - 1.8 8.6 5.2 4 7.5 5.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Trypsin PF00089.26 CBY36103.1 - 1.3e-15 57.9 1.3 1.4e-15 57.7 1.3 1.1 1 0 0 1 1 1 1 Trypsin LRR_6 PF13516.6 CBY36103.1 - 0.12 12.4 0.0 0.46 10.7 0.0 2.1 1 0 0 1 1 1 0 Leucine Rich repeat TAF PF02969.17 CBY36105.1 - 0.043 14.0 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Glyco_hydro_9 PF00759.19 CBY36106.1 - 1.5e-103 347.4 0.7 2.3e-103 346.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Thyroglobulin_1 PF00086.18 CBY36106.1 - 3.2e-07 29.9 1.6 8e-07 28.6 1.6 1.6 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Homeodomain PF00046.29 CBY36107.1 - 9.1e-23 79.9 10.3 9.8e-23 79.8 8.3 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY36107.1 - 0.0057 16.5 0.5 0.0057 16.5 0.5 1.8 2 0 0 2 2 2 1 Homeobox KN domain GAIN_A PF18619.1 CBY36107.1 - 0.023 14.9 0.9 0.053 13.7 0.9 1.6 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A HlyIII PF03006.20 CBY36108.1 - 2.8e-40 138.4 16.2 3.5e-40 138.1 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.8 CBY36108.1 - 0.55 10.4 2.3 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 SET PF00856.28 CBY36109.1 - 0.00077 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-C2H2_4 PF13894.6 CBY36109.1 - 0.0028 18.3 24.7 0.69 10.9 1.8 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY36109.1 - 0.09 13.3 21.3 0.31 11.6 2.0 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CBY36109.1 - 0.37 11.1 7.1 0.18 12.1 4.4 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon TRAM_LAG1_CLN8 PF03798.16 CBY36110.1 - 5.6e-21 75.2 13.4 5.6e-21 75.2 13.4 1.5 2 0 0 2 2 2 1 TLC domain SNF2_N PF00176.23 CBY36111.1 - 9.9e-51 172.5 1.4 3.5e-50 170.7 1.4 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY36111.1 - 2.4e-16 60.0 0.0 3.5e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY36111.1 - 3.5e-11 43.4 0.0 1.6e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBY36111.1 - 1.5e-05 24.3 0.4 6.1e-05 22.3 0.4 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_34 PF13872.6 CBY36111.1 - 3.2e-05 23.0 0.1 6.5e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DEAD PF00270.29 CBY36111.1 - 4e-05 23.4 0.0 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase C2 PF00168.30 CBY36112.1 - 4.2e-23 81.6 0.1 1.1e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 C2 domain C1_1 PF00130.22 CBY36112.1 - 1.6e-15 56.7 15.8 1.4e-07 31.3 2.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CBY36112.1 - 4.2e-12 46.0 0.1 5.9e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36112.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_2 PF03107.16 CBY36112.1 - 6.3e-06 26.4 13.3 0.00037 20.8 2.5 2.5 2 0 0 2 2 2 2 C1 domain Zf_RING PF16744.5 CBY36112.1 - 2.6e-05 24.2 9.0 0.0057 16.7 0.5 2.9 3 0 0 3 3 2 2 KIAA1045 RING finger zf-RING_9 PF13901.6 CBY36112.1 - 0.031 14.2 12.0 0.057 13.4 1.4 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Zn_ribbon_17 PF17120.5 CBY36112.1 - 0.13 11.9 11.8 0.89 9.2 4.5 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBY36112.1 - 0.53 10.2 19.8 2.1 8.3 7.4 3.0 2 1 1 3 3 3 0 PHD-finger zf-RING-like PF08746.11 CBY36112.1 - 1.5 9.2 17.8 0.31 11.4 2.6 2.9 2 1 0 2 2 2 0 RING-like domain FYVE PF01363.21 CBY36112.1 - 1.9 8.7 14.5 24 5.2 6.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger Prok-RING_1 PF14446.6 CBY36112.1 - 4.2 7.4 14.8 4 7.5 1.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_15 PF17032.5 CBY36112.1 - 5.4 7.8 12.1 3.1 8.6 6.3 2.6 1 1 1 2 2 2 0 zinc-ribbon family DZR PF12773.7 CBY36112.1 - 5.9 7.0 12.9 3.3 7.8 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon PHD_4 PF16866.5 CBY36112.1 - 7.7 6.7 12.1 11 6.2 3.0 2.7 1 1 1 2 2 2 0 PHD-finger PHD_2 PF13831.6 CBY36112.1 - 7.8 6.1 17.4 1.3 8.6 1.0 3.9 4 0 0 4 4 4 0 PHD-finger Pkinase PF00069.25 CBY36113.1 - 1.1e-18 67.6 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36113.1 - 3.7e-09 36.3 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PfkB PF00294.24 CBY36114.1 - 5.6e-31 108.0 0.0 8.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3580 PF12117.8 CBY36114.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Glyco_hydro_3_C PF01915.22 CBY36114.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain eIF-3c_N PF05470.12 CBY36114.1 - 0.67 8.2 6.9 1 7.6 6.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1980 PF09323.10 CBY36114.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Apt1 PF10351.9 CBY36114.1 - 2.4 6.9 6.9 3.2 6.5 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BRCA2 PF00634.18 CBY36115.1 - 1.6e-05 24.4 14.2 0.11 12.1 0.0 6.1 6 0 0 6 6 6 3 BRCA2 repeat Utp11 PF03998.13 CBY36115.1 - 0.013 15.5 3.8 0.37 10.7 1.0 2.7 2 0 0 2 2 2 0 Utp11 protein Glyco_transf_64 PF09258.10 CBY36117.1 - 6.1e-89 297.5 0.0 1.3e-88 296.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CBY36117.1 - 4.3e-12 45.9 0.0 2.2e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Exostosin family Glycos_transf_2 PF00535.26 CBY36117.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Fib_alpha PF08702.10 CBY36117.1 - 0.047 13.9 1.6 3.4 7.9 3.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_tranf_2_3 PF13641.6 CBY36117.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 KxDL PF10241.9 CBY36117.1 - 0.14 12.4 3.2 0.28 11.5 3.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF16 PF01519.16 CBY36117.1 - 3 8.4 5.6 6.5 7.3 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Methyltransf_PK PF05891.12 CBY36118.1 - 9.2e-63 211.7 0.0 1.1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CBY36118.1 - 7.6e-06 26.5 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY36118.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY36118.1 - 4.4e-05 24.1 0.1 0.00012 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY36118.1 - 0.051 14.3 0.0 0.078 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY36118.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 CBY36118.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Mei5 PF10376.9 CBY36118.1 - 0.13 12.1 0.2 0.6 9.9 0.0 1.8 2 0 0 2 2 2 0 Double-strand recombination repair protein zf-CCHH PF10283.9 CBY36119.1 - 1.1e-19 70.0 11.7 2.3e-11 43.5 2.7 2.4 2 0 0 2 2 2 2 PBZ domain PBP1_TM PF14812.6 CBY36119.1 - 3 8.3 8.0 0.79 10.1 3.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chromo PF00385.24 CBY36120.1 - 1.3e-19 69.8 1.7 5.2e-16 58.3 0.9 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY36120.1 - 6.9e-14 51.7 0.1 2.2e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 CBY36120.1 - 3.2e-06 27.2 0.1 0.00025 21.2 0.1 2.4 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 SET PF00856.28 CBY36121.1 - 4.7e-21 75.9 1.9 4.3e-20 72.8 0.1 2.7 2 1 0 2 2 2 1 SET domain PWWP PF00855.17 CBY36122.1 - 1.4e-23 83.1 19.7 8.7e-14 51.7 0.2 4.7 4 1 0 4 4 4 2 PWWP domain PHD PF00628.29 CBY36122.1 - 1e-05 25.3 6.3 1e-05 25.3 6.3 5.9 4 1 1 5 5 5 2 PHD-finger zf-C2H2_9 PF16293.5 CBY36122.1 - 0.74 9.7 6.5 4 7.4 2.0 3.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) Thioredoxin PF00085.20 CBY36123.1 - 9.8e-13 48.0 0.0 1.1e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBY36123.1 - 0.03 14.8 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L24e PF01246.20 CBY36124.1 - 1.7e-32 111.5 7.6 1.7e-32 111.5 7.6 2.1 3 1 0 3 3 3 1 Ribosomal protein L24e MCM PF00493.23 CBY36125.1 - 2.3e-100 334.3 0.0 3.7e-100 333.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY36125.1 - 2.6e-34 117.8 0.3 4.4e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY36125.1 - 1e-23 83.5 3.5 1.3e-23 83.2 0.8 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CBY36125.1 - 1.1e-10 42.0 0.3 4.2e-10 40.1 0.3 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY36125.1 - 2.3e-09 36.9 0.0 1.1e-06 28.2 0.0 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 CBY36125.1 - 4.7e-08 33.5 33.8 4.7e-08 33.5 33.8 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 CBY36125.1 - 1.3e-06 28.4 0.0 4.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY36125.1 - 1.2e-05 25.2 0.0 0.0014 18.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY36125.1 - 0.0006 19.6 0.0 0.011 15.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CBY36125.1 - 0.016 15.6 0.0 0.059 13.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 CBY36125.1 - 0.29 11.3 1.4 0.77 9.9 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain FXa_inhibition PF14670.6 CBY36126.1 - 5.5e-08 33.0 7.6 9.3e-08 32.2 7.6 1.4 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY36126.1 - 0.041 13.8 0.6 0.074 13.0 0.6 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like EGF PF00008.27 CBY36126.1 - 1.1 9.6 7.1 2.8 8.3 7.1 1.7 1 0 0 1 1 1 0 EGF-like domain E_raikovi_mat PF06360.11 CBY36126.1 - 6.3 7.3 7.8 59 4.2 6.7 2.5 1 1 1 2 2 2 0 Euplotes raikovi mating pheromone Troponin PF00992.20 CBY36127.1 - 6.2e-24 84.8 33.1 3e-21 76.1 25.6 2.0 1 1 1 2 2 2 2 Troponin p450 PF00067.22 CBY36129.1 - 1.3e-46 159.4 0.2 1.7e-46 159.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 TIG PF01833.24 CBY36130.1 - 2.1e-20 72.6 21.6 4.7e-08 33.0 0.2 6.0 6 0 0 6 6 6 4 IPT/TIG domain GLEYA PF10528.9 CBY36130.1 - 2.8e-06 27.7 0.9 2.1e-05 24.8 0.9 2.7 1 0 0 1 1 1 1 GLEYA domain FLgD_tudor PF13861.6 CBY36130.1 - 0.96 9.7 8.1 2.9 8.2 6.2 2.8 2 0 0 2 2 2 0 FlgD Tudor-like domain Biotin_lipoyl PF00364.22 CBY36131.1 - 8.7e-16 57.5 0.4 1.1e-15 57.2 0.4 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 CBY36131.1 - 0.0016 18.3 0.2 0.0022 17.9 0.2 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 CBY36131.1 - 0.0043 16.9 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 CBY36131.1 - 0.0068 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CBY36131.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.7 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TPR_19 PF14559.6 CBY36132.1 - 2.4e-12 47.2 3.5 6.1e-05 23.5 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36132.1 - 6.9e-12 45.1 0.3 0.00035 21.2 0.2 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36132.1 - 8.3e-10 38.0 7.1 0.00051 20.0 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36132.1 - 3.3e-07 30.8 0.0 8e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY36132.1 - 6.3e-06 25.8 5.6 0.026 14.4 0.1 3.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY36132.1 - 1.2e-05 24.9 1.8 0.048 13.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36132.1 - 1.9e-05 25.0 0.3 7 7.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36132.1 - 3.1e-05 23.9 2.3 0.0045 17.1 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CBY36132.1 - 6.7e-05 22.9 0.0 0.0023 17.9 0.0 2.2 1 1 1 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 CBY36132.1 - 0.00027 20.3 0.0 0.00076 18.8 0.1 1.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36132.1 - 0.00057 20.1 2.0 8.9 6.9 0.0 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.8 CBY36132.1 - 0.00077 18.5 2.9 0.084 11.8 0.3 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 CBY36132.1 - 0.0041 17.4 2.1 0.084 13.2 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4852 PF16144.5 CBY36132.1 - 0.021 14.9 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4852) TPR_9 PF13371.6 CBY36132.1 - 0.025 14.7 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 CBY36132.1 - 0.028 14.7 7.0 0.93 9.9 0.2 3.4 4 0 0 4 4 3 0 PPR repeat ChAPs PF09295.10 CBY36132.1 - 0.064 12.3 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 CBY36132.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Memo PF01875.17 CBY36133.1 - 1.1e-85 287.0 0.1 1.3e-85 286.9 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein ATP_bind_3 PF01171.20 CBY36134.1 - 3e-17 63.0 0.0 1.3e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 CBY36134.1 - 1.1e-16 60.0 2.0 1.1e-16 60.0 2.0 3.6 3 0 0 3 3 3 1 Zinc-ribbon zf-LITAF-like PF10601.9 CBY36135.1 - 1.3e-16 60.6 23.1 1.7e-16 60.2 23.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-LITAF-like PF10601.9 CBY36136.1 - 1.4e-22 79.7 12.3 1.9e-22 79.3 12.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain JAMP PF05571.12 CBY36137.1 - 3.3e-25 89.3 9.8 5.7e-25 88.5 9.8 1.3 1 1 0 1 1 1 1 JNK1/MAPK8-associated membrane protein JAMP PF05571.12 CBY36138.1 - 4e-08 33.3 7.4 5e-08 32.9 7.4 1.1 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein zf-LITAF-like PF10601.9 CBY36139.1 - 1.7e-16 60.2 9.7 2e-16 60.0 9.7 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-RING_4 PF14570.6 CBY36139.1 - 0.27 11.1 10.1 0.44 10.4 3.8 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Mob1_phocein PF03637.17 CBY36140.1 - 1.5e-32 112.9 0.6 2.5e-32 112.2 0.6 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF3574 PF12098.8 CBY36143.1 - 0.12 12.2 0.3 0.18 11.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3574) Actin PF00022.19 CBY36144.1 - 2.2e-152 507.4 0.0 7.1e-152 505.7 0.0 1.6 1 1 0 1 1 1 1 Actin YopE_N PF09020.10 CBY36145.1 - 0.03 14.6 0.3 0.031 14.5 0.3 1.3 1 1 0 1 1 1 0 YopE, N terminal DUF4038 PF13204.6 CBY36145.1 - 0.067 12.8 0.0 0.077 12.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Peptidase_M16_C PF05193.21 CBY36146.1 - 1.3e-07 31.8 0.0 1.4e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain FAM183 PF14886.6 CBY36148.1 - 2e-25 89.6 0.3 2.4e-25 89.3 0.3 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related Sec10 PF07393.11 CBY36149.1 - 3.4e-120 402.6 16.2 2.8e-71 241.0 2.1 3.0 1 1 2 3 3 3 3 Exocyst complex component Sec10 V_ATPase_I PF01496.19 CBY36149.1 - 0.025 12.5 3.0 0.046 11.7 2.8 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HHH_6 PF14579.6 CBY36149.1 - 0.076 13.3 0.2 0.24 11.7 0.2 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1043 PF06295.12 CBY36149.1 - 0.14 12.2 5.4 0.085 12.9 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 CBY36149.1 - 1.1 9.3 9.4 1.3 9.1 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) OmpH PF03938.14 CBY36149.1 - 2.4 8.5 14.3 0.15 12.4 4.2 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 CBY36149.1 - 5.8 7.3 9.2 1.1 9.7 3.5 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Phospholip_A2_1 PF00068.19 CBY36150.1 - 3.9e-13 49.9 9.7 3.9e-13 49.9 9.7 2.2 2 1 0 2 2 2 1 Phospholipase A2 TPR_12 PF13424.6 CBY36151.1 - 5.3e-11 42.6 10.3 3.9e-06 27.1 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY36151.1 - 5.8e-06 25.9 3.5 0.00033 20.1 1.2 2.4 2 0 0 2 2 2 2 MalT-like TPR region zf-RING_11 PF17123.5 CBY36151.1 - 0.00065 19.4 1.4 0.0015 18.2 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger Rapsyn_N PF10579.9 CBY36151.1 - 0.0033 17.5 0.2 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.6 CBY36151.1 - 0.0079 15.6 6.6 0.0079 15.6 6.6 2.0 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.6 CBY36151.1 - 0.011 16.1 7.0 0.032 14.6 7.0 1.9 1 0 0 1 1 1 0 Ring finger domain TPR_19 PF14559.6 CBY36151.1 - 0.034 14.6 5.4 0.42 11.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY36151.1 - 0.038 14.1 5.9 0.81 9.8 1.2 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 CBY36151.1 - 0.039 14.6 0.1 8.9 7.3 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36151.1 - 0.12 13.0 3.0 2.3 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 CBY36151.1 - 0.13 12.2 3.4 0.46 10.4 3.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY36151.1 - 0.23 11.4 8.5 0.62 10.1 8.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_10 PF13374.6 CBY36151.1 - 0.27 11.2 4.6 11 6.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36151.1 - 0.28 11.5 10.8 55 4.3 0.1 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY36151.1 - 1 9.6 6.5 8.1 6.7 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat YHYH PF14240.6 CBY36152.1 - 6.4e-21 75.2 2.9 7.3e-14 52.2 0.1 2.6 1 1 1 2 2 2 2 YHYH protein Anti-TRAP PF15777.5 CBY36152.1 - 0.08 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5589 PF17672.1 CBY36155.1 - 0.11 12.5 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5589) C2-set_2 PF08205.12 CBY36156.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_3 PF13927.6 CBY36156.1 - 0.12 13.0 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain VCX_VCY PF15231.6 CBY36158.1 - 0.00048 20.8 2.4 0.00048 20.8 2.4 1.9 1 1 1 2 2 2 1 Variable charge X/Y family Pkinase PF00069.25 CBY36159.1 - 5e-62 209.7 0.0 7e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CNH PF00780.22 CBY36159.1 - 3.1e-50 171.3 0.0 4.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain Pkinase_Tyr PF07714.17 CBY36159.1 - 3e-44 151.3 0.0 4.3e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY36159.1 - 4.9e-06 25.6 0.9 9.6e-06 24.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CBY36159.1 - 0.0025 17.2 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY36159.1 - 0.004 17.1 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY36159.1 - 0.045 13.1 0.7 0.085 12.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TDP43_N PF18694.1 CBY36160.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Transactive response DNA-binding protein N-terminal domain NTF2 PF02136.20 CBY36161.1 - 3.7e-23 82.4 0.2 7.2e-23 81.4 0.2 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CBY36161.1 - 6.4e-18 64.3 0.7 1e-17 63.7 0.7 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY36161.1 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 CBY36161.1 - 0.002 18.1 0.1 0.0043 17.1 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif GRP PF07172.11 CBY36161.1 - 0.85 10.4 12.5 2 9.1 12.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family adh_short PF00106.25 CBY36162.1 - 2.2e-26 92.6 0.0 2.7e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY36162.1 - 1.7e-16 60.5 0.0 1.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY36162.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 CBY36163.1 - 1.8e-25 89.6 0.4 1.5e-20 73.5 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY36163.1 - 2.7e-16 59.9 0.1 3.7e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY36163.1 - 1.1e-07 32.0 0.7 4.1e-07 30.1 0.2 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 CBY36163.1 - 0.034 13.9 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HSP70 PF00012.20 CBY36164.1 - 7.5e-245 813.7 13.1 8.5e-245 813.5 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY36164.1 - 2.4e-15 56.2 2.2 5.2e-15 55.1 2.2 1.5 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CBY36164.1 - 2e-05 24.4 0.0 4.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CBY36164.1 - 0.0011 19.4 1.6 0.0077 16.6 0.5 2.6 2 1 0 2 2 2 1 Cell division protein FtsA YkyA PF10368.9 CBY36164.1 - 0.089 12.5 10.2 0.17 11.5 10.2 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Caskin-tail PF16632.5 CBY36164.1 - 0.09 13.2 2.8 0.33 11.4 2.8 2.0 1 0 0 1 1 1 0 C-terminal region of Caskin GFRP PF06399.13 CBY36164.1 - 0.1 12.5 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) TetR_C_25 PF17933.1 CBY36164.1 - 0.12 12.6 0.1 2.3 8.6 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PXA PF02194.15 CBY36165.1 - 1.3e-34 119.8 2.3 1.3e-34 119.8 2.3 2.7 2 0 0 2 2 2 1 PXA domain RGS PF00615.19 CBY36165.1 - 7.3e-17 61.7 6.3 9.2e-17 61.4 2.5 2.9 2 1 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.12 CBY36165.1 - 6.8e-16 58.8 0.0 7.5e-15 55.5 0.0 2.9 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CBY36165.1 - 2.9e-09 36.9 0.3 8.9e-09 35.3 0.3 1.9 1 0 0 1 1 1 1 PX domain NIDO PF06119.14 CBY36166.1 - 0.00081 20.3 0.2 0.0024 18.8 0.1 1.9 2 0 0 2 2 2 1 Nidogen-like TSP_1 PF00090.19 CBY36167.1 - 6.5e-09 35.9 60.8 3.2e-07 30.5 8.8 6.2 5 1 0 5 5 5 3 Thrombospondin type 1 domain cEGF PF12662.7 CBY36167.1 - 5.1e-05 23.1 0.6 0.00028 20.7 0.6 2.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY36167.1 - 0.00016 21.8 24.9 0.0002 21.5 7.2 4.2 3 0 0 3 3 3 2 Calcium-binding EGF domain DUF5034 PF16437.5 CBY36167.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5034) EamA PF00892.20 CBY36168.1 - 2e-05 24.8 17.8 0.00086 19.5 13.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3040 PF11239.8 CBY36168.1 - 0.14 12.4 7.0 1.4 9.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Ank_4 PF13637.6 CBY36169.1 - 3.3e-07 30.7 0.1 0.044 14.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY36169.1 - 7.5e-07 29.7 0.2 4.7e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY36169.1 - 0.00013 22.2 0.3 0.00038 20.7 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY36169.1 - 0.00026 21.3 0.5 0.38 11.3 0.1 3.9 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 CBY36169.1 - 0.076 13.6 0.0 1.7 9.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat GET2 PF08690.10 CBY36169.1 - 2.6 7.6 8.0 4.8 6.8 8.0 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 ATP-synt_S1 PF05827.12 CBY36170.1 - 4.1e-09 36.4 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PTP_tm PF18861.1 CBY36170.1 - 0.0011 19.0 0.4 0.0016 18.5 0.4 1.4 1 1 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Lamp PF01299.17 CBY36170.1 - 0.002 18.0 0.0 0.0034 17.2 0.0 1.4 1 1 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) SKI PF01202.22 CBY36171.1 - 0.0045 17.1 0.2 0.0077 16.4 0.1 1.4 1 1 0 1 1 1 1 Shikimate kinase DUF410 PF04190.13 CBY36171.1 - 0.0063 16.3 0.2 0.0073 16.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Myb_CC_LHEQLE PF14379.6 CBY36171.1 - 0.038 13.7 1.0 0.46 10.2 0.1 2.1 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif TPR_12 PF13424.6 CBY36172.1 - 9.9e-05 22.6 0.2 0.03 14.6 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBY36172.1 - 0.00016 21.4 0.0 0.0048 16.7 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY36172.1 - 0.001 19.0 0.0 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY36172.1 - 0.0017 18.4 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 CBY36172.1 - 0.002 17.6 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 CBY36172.1 - 0.0059 16.6 0.0 0.066 13.4 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 CBY36172.1 - 0.045 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat Hairy_orange PF07527.13 CBY36172.1 - 0.053 13.7 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Hairy Orange Antimicrobial_7 PF08102.11 CBY36172.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Scorpion antimicrobial peptide TPR_4 PF07721.14 CBY36172.1 - 0.17 12.6 0.0 8.9 7.3 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 CBY36173.1 - 0.015 15.1 0.3 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region DUF2153 PF09921.9 CBY36173.1 - 0.026 14.3 1.8 0.053 13.3 1.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Oscp1 PF10188.9 CBY36173.1 - 0.085 13.0 1.6 0.1 12.7 0.2 1.8 2 0 0 2 2 2 0 Organic solute transport protein 1 RICH PF05062.12 CBY36173.1 - 0.55 10.6 6.1 0.086 13.2 2.0 1.8 2 0 0 2 2 2 0 RICH domain Pkinase PF00069.25 CBY36174.1 - 4.4e-23 82.0 0.0 4e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36174.1 - 1.4e-22 80.3 0.1 6e-22 78.2 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36175.1 - 6e-42 143.8 0.0 1.1e-41 143.0 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36175.1 - 3.3e-31 108.5 0.0 5.2e-31 107.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBY36175.1 - 0.0037 16.3 0.3 0.0055 15.7 0.3 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBY36175.1 - 0.0097 14.7 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4486 PF14858.6 CBY36175.1 - 0.029 12.9 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) YrbL-PhoP_reg PF10707.9 CBY36175.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 CBY36176.1 - 6.1e-45 153.6 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36176.1 - 7e-38 130.4 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY36176.1 - 0.17 10.6 0.0 0.17 10.6 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Ribonuc_L-PSP PF01042.21 CBY36177.1 - 3.4e-44 149.7 0.4 4e-44 149.5 0.4 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 CBY36177.1 - 0.0081 16.3 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease SRF-TF PF00319.18 CBY36178.1 - 4.3e-13 48.5 0.3 8e-13 47.7 0.3 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3020 PF11223.8 CBY36178.1 - 1 9.9 5.9 2.3 8.8 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3020) Galactosyl_T PF01762.21 CBY36180.1 - 3.6e-21 75.9 0.0 9.2e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Galactosyltransferase RepL PF05732.11 CBY36180.1 - 0.076 12.4 2.6 0.19 11.2 0.7 2.1 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) Sulfotransfer_3 PF13469.6 CBY36181.1 - 0.00031 21.2 0.0 0.18 12.1 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY36181.1 - 0.0028 17.2 1.7 0.21 11.0 1.5 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Mucin2_WxxW PF13330.6 CBY36182.1 - 1.8e-154 503.0 106.8 1e-14 55.1 1.8 13.9 14 0 0 14 14 14 13 Mucin-2 protein WxxW repeating region ABC_tran PF00005.27 CBY36183.1 - 7.5e-36 123.7 0.0 1.7e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CBY36183.1 - 2.5e-21 76.6 2.0 4.1e-21 75.9 2.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBY36183.1 - 3.2e-06 26.7 2.6 1.4e-05 24.7 0.2 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBY36183.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 CBY36183.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY36183.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 CBY36183.1 - 0.021 14.9 0.2 0.066 13.3 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 CBY36183.1 - 0.023 15.0 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBY36183.1 - 0.024 14.4 0.1 0.062 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CBY36183.1 - 0.028 14.7 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBY36183.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY36183.1 - 0.076 12.9 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Tad PF13400.6 CBY36183.1 - 0.08 13.3 0.8 0.22 11.8 0.8 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like SbcCD_C PF13558.6 CBY36183.1 - 0.091 13.0 0.6 3 8.2 0.3 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 CBY36183.1 - 0.12 12.7 2.1 1.2 9.5 0.1 3.1 3 1 0 3 3 3 0 RNA helicase ATP_bind_1 PF03029.17 CBY36183.1 - 0.13 12.0 0.5 18 5.0 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 CBY36183.1 - 0.13 12.7 0.1 1.2 9.6 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RTTN_N PF14726.6 CBY36184.1 - 5.5e-18 65.6 0.0 5.5e-18 65.6 0.0 3.8 4 0 0 4 4 4 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 CBY36184.1 - 0.063 13.6 0.0 3.8 8.0 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Kinesin PF00225.23 CBY36185.1 - 3.6e-105 351.6 2.5 7.2e-105 350.6 2.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY36185.1 - 1.3e-46 158.2 0.1 3.1e-46 157.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding Sec34 PF04136.15 CBY36185.1 - 0.0015 18.4 12.4 0.057 13.3 2.3 2.5 1 1 1 2 2 2 2 Sec34-like family MAD PF05557.13 CBY36185.1 - 0.008 14.6 23.7 0.015 13.7 23.7 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 CBY36185.1 - 0.019 15.0 27.1 0.056 13.5 27.1 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY36185.1 - 0.021 14.9 12.9 0.28 11.2 3.7 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY36185.1 - 0.021 12.8 10.8 0.016 13.1 8.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 CBY36185.1 - 0.025 13.9 30.0 0.29 10.5 29.6 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 CBY36185.1 - 0.041 13.9 10.0 0.12 12.3 10.0 1.9 1 1 0 1 1 1 0 Laminin Domain II FPP PF05911.11 CBY36185.1 - 0.063 11.5 22.3 0.12 10.5 22.3 1.6 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Prominin PF05478.11 CBY36185.1 - 0.22 9.4 9.0 0.34 8.8 9.0 1.2 1 0 0 1 1 1 0 Prominin DUF3450 PF11932.8 CBY36185.1 - 0.26 10.5 25.2 0.69 9.2 10.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBY36185.1 - 0.34 9.8 30.4 0.33 9.8 13.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CBY36185.1 - 0.35 11.3 15.6 0.32 11.4 2.8 3.8 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) PI3K_P85_iSH2 PF16454.5 CBY36185.1 - 0.41 10.2 28.8 0.14 11.8 23.1 2.8 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Exonuc_VII_L PF02601.15 CBY36185.1 - 0.74 9.3 20.2 0.021 14.4 13.4 1.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 CBY36185.1 - 0.78 10.3 22.4 5.2 7.6 17.8 3.3 3 1 0 3 3 1 0 Protein of unknown function DUF16 HIP1_clath_bdg PF16515.5 CBY36185.1 - 0.91 10.2 26.2 0.75 10.4 11.8 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 CBY36185.1 - 1 9.5 19.6 0.03 14.4 5.5 2.9 1 1 0 2 2 2 0 TolA binding protein trimerisation DUF812 PF05667.11 CBY36185.1 - 1.1 8.1 30.6 5.3 5.8 27.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Nup88 PF10168.9 CBY36185.1 - 1.1 7.0 18.4 1.6 6.4 18.4 1.2 1 0 0 1 1 1 0 Nuclear pore component Laminin_I PF06008.14 CBY36185.1 - 1.2 8.8 24.3 0.13 11.9 6.1 2.7 2 1 1 3 3 2 0 Laminin Domain I MetOD2 PF18548.1 CBY36185.1 - 1.4 9.0 12.9 1.4 9.1 1.1 3.3 2 1 1 3 3 3 0 Metanogen output domain 2 DUF948 PF06103.11 CBY36185.1 - 1.4 9.2 6.8 15 5.9 1.2 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 CBY36185.1 - 1.5 9.1 9.3 6.5 7.1 2.7 3.4 2 1 0 3 3 2 0 Proteins of 100 residues with WXG APG6_N PF17675.1 CBY36185.1 - 1.9 9.0 36.3 0.56 10.7 17.6 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2968 PF11180.8 CBY36185.1 - 2.1 8.0 19.3 3.6 7.2 7.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4407 PF14362.6 CBY36185.1 - 2.2 7.6 19.4 0.9 8.8 16.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ERM PF00769.19 CBY36185.1 - 2.9 7.6 37.9 0.1 12.4 28.4 2.6 2 1 1 3 3 2 0 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 CBY36185.1 - 3 8.0 29.9 0.58 10.3 10.2 3.5 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 ATG16 PF08614.11 CBY36185.1 - 3.1 8.0 25.7 19 5.4 17.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 CBY36185.1 - 3.4 7.8 12.3 3.4 7.8 6.6 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 CBY36185.1 - 3.5 8.4 18.9 11 6.9 6.1 3.1 2 1 1 3 3 2 0 Occludin homology domain LXG PF04740.12 CBY36185.1 - 3.6 7.3 18.0 3.1 7.4 3.2 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily Sec20 PF03908.13 CBY36185.1 - 4 7.4 6.4 7.2 6.6 0.7 3.0 2 0 0 2 2 2 0 Sec20 Sec8_exocyst PF04048.14 CBY36185.1 - 4.1 7.3 15.1 0.31 10.9 1.9 3.7 3 1 0 4 4 3 0 Sec8 exocyst complex component specific domain Bacillus_HBL PF05791.11 CBY36185.1 - 4.7 7.0 11.5 1.4 8.7 6.1 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 CBY36185.1 - 6 6.5 24.8 2.5 7.7 18.5 2.8 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 CBY36185.1 - 8.9 4.8 24.3 4.5 5.8 11.8 2.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A KxDL PF10241.9 CBY36185.1 - 9.9 6.5 22.6 1.9 8.8 6.2 3.2 2 1 2 4 4 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 CBY36185.1 - 10 6.8 15.4 17 6.1 3.3 3.3 2 1 1 3 3 2 0 Syntaxin 6, N-terminal HMG_CoA_synt_C PF08540.10 CBY36186.1 - 0.026 14.2 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal zf-C3HC PF07967.13 CBY36186.1 - 0.027 14.5 1.2 0.06 13.4 0.8 1.7 1 1 1 2 2 2 0 C3HC zinc finger-like UPAR_LY6 PF00021.21 CBY36186.1 - 0.35 11.6 7.5 1.1 10.1 7.5 1.8 1 1 0 1 1 1 0 u-PAR/Ly-6 domain MDD_C PF18376.1 CBY36187.1 - 0.15 11.7 1.4 0.23 11.2 0.1 1.7 1 1 1 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Paf1 PF03985.13 CBY36187.1 - 0.46 9.4 10.3 0.5 9.3 10.3 1.0 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 CBY36187.1 - 1.7 7.9 8.4 2.1 7.6 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 CBY36187.1 - 2 7.4 14.8 2.3 7.2 14.8 1.1 1 0 0 1 1 1 0 Pes-10 Nop14 PF04147.12 CBY36187.1 - 3.2 5.8 15.2 3.7 5.7 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family CH PF00307.31 CBY36189.1 - 3.6e-07 30.3 0.0 4.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_LMP1 PF05297.11 CBY36191.1 - 0.11 11.6 1.8 0.17 11.0 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Macoilin PF09726.9 CBY36191.1 - 0.4 9.2 9.7 0.49 8.9 9.7 1.1 1 0 0 1 1 1 0 Macoilin family bZIP_2 PF07716.15 CBY36193.1 - 7.5e-17 61.2 9.3 7.5e-17 61.2 9.3 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY36193.1 - 3.6e-07 30.2 7.8 7.7e-07 29.1 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor MIP PF00230.20 CBY36194.1 - 3.6e-39 134.8 11.0 4.7e-39 134.4 11.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sulfate_transp PF00916.20 CBY36194.1 - 0.001 17.9 1.6 0.001 17.9 1.6 1.6 2 0 0 2 2 2 1 Sulfate permease family DUF5637 PF18687.1 CBY36194.1 - 0.054 13.5 1.8 0.15 12.1 1.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5637) DUF2093 PF09866.9 CBY36194.1 - 0.45 10.0 4.3 7.1 6.2 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) B12D PF06522.11 CBY36194.1 - 0.59 10.0 1.8 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BUD22 PF09073.10 CBY36195.1 - 5.5 6.2 10.7 6.1 6.1 10.7 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CBY36195.1 - 6.1 6.2 12.2 7.2 5.9 12.2 1.1 1 0 0 1 1 1 0 SDA1 Histone PF00125.24 CBY36196.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY36196.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY36196.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY36196.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY36196.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBY36196.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CBY36197.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY36197.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY36197.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY36197.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY36197.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY36197.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY36197.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY36197.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Linker_histone PF00538.19 CBY36198.1 - 1.4e-29 102.2 1.1 1.4e-29 102.2 1.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 CBY36198.1 - 0.00032 20.8 37.7 0.00032 20.8 37.7 2.4 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Histone_H2A_C PF16211.5 CBY36199.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY36199.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36199.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY36200.1 - 1.4e-21 77.2 0.6 1.7e-21 76.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36200.1 - 5.4e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY36200.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY36200.1 - 0.00041 20.4 0.3 0.00044 20.3 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY36200.1 - 0.033 14.4 0.7 0.087 13.1 0.7 1.7 1 1 0 1 1 1 0 CENP-W protein Lectin_leg-like PF03388.13 CBY36202.1 - 2.4e-27 95.8 0.0 4.6e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family DUF1664 PF07889.12 CBY36202.1 - 1.1 9.3 10.2 4.7 7.3 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ArfGap PF01412.18 CBY36203.1 - 8.4e-31 106.5 0.9 1.8e-30 105.4 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NOG1_N PF17835.1 CBY36203.1 - 0.0033 17.4 0.7 0.0091 16.0 0.3 1.9 1 1 1 2 2 2 1 NOG1 N-terminal helical domain Prok-TraM PF09228.10 CBY36203.1 - 0.074 13.4 0.7 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Scs3p PF10261.9 CBY36204.1 - 4.7e-16 59.0 17.6 7.7e-12 45.2 6.6 2.7 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM YIF1 PF03878.15 CBY36205.1 - 1.8e-75 253.5 0.8 2.6e-75 253.0 0.8 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CBY36205.1 - 2.4e-10 40.4 2.3 3.9e-10 39.7 2.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CBY36205.1 - 0.029 14.1 3.8 0.051 13.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2269 PF10027.9 CBY36205.1 - 0.036 14.1 1.2 0.073 13.1 0.1 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF4233 PF14017.6 CBY36205.1 - 1.2 9.5 7.8 2.7 8.4 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) TAF PF02969.17 CBY36206.1 - 0.00012 22.2 0.1 0.00023 21.3 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Semialdhyde_dh PF01118.24 CBY36207.1 - 0.0018 18.7 0.1 0.0039 17.6 0.1 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 CBY36207.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_7 PF13241.6 CBY36207.1 - 0.05 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding CbiD PF01888.17 CBY36207.1 - 0.063 12.6 2.0 0.89 8.8 2.6 2.2 1 1 1 2 2 2 0 CbiD Shikimate_DH PF01488.20 CBY36207.1 - 0.071 13.2 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 CBY36207.1 - 0.081 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Acetyltransf_18 PF18014.1 CBY36208.1 - 1.9e-09 37.4 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4459 PF14673.6 CBY36208.1 - 0.074 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) DUF1999 PF09390.10 CBY36208.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) AMP-binding PF00501.28 CBY36209.1 - 1.1e-95 320.7 0.0 1.4e-95 320.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY36209.1 - 0.013 16.4 0.0 0.034 15.1 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Ice_nucleation PF00818.17 CBY36209.1 - 9.4 6.6 11.0 2.9 8.2 0.2 3.7 3 0 0 3 3 3 0 Ice nucleation protein repeat MIP PF00230.20 CBY36210.1 - 1.5e-23 83.7 2.9 1.8e-23 83.5 2.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 CBY36210.1 - 2.1 8.7 6.0 0.85 10.0 0.1 2.6 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Mab-21 PF03281.14 CBY36211.1 - 6.6e-24 84.7 0.0 9.1e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein RRM_1 PF00076.22 CBY36213.1 - 2.8e-30 103.9 0.1 8.6e-20 70.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBY36213.1 - 1.1e-05 25.2 0.0 0.01 15.7 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBY36213.1 - 4.2e-05 23.6 0.0 0.39 10.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBY36213.1 - 0.0099 16.1 0.2 2.9 8.1 0.3 2.7 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CBY36213.1 - 0.043 13.8 0.1 0.47 10.5 0.2 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBY36214.1 - 2.8e-27 94.3 0.1 7.5e-19 67.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY36214.1 - 0.00015 21.8 0.0 0.75 10.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CBY36214.1 - 0.00024 20.9 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CBY36214.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trp_DMAT PF11991.8 CBY36217.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.0 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase Calsequestrin PF01216.17 CBY36217.1 - 0.073 12.1 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Calsequestrin His_Phos_1 PF00300.22 CBY36218.1 - 9.3e-34 116.8 0.1 1e-33 116.7 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2235 PF09994.9 CBY36218.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) 14-3-3 PF00244.20 CBY36219.1 - 0.046 13.2 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 14-3-3 protein Met_10 PF02475.16 CBY36220.1 - 7.6e-42 143.3 0.0 1.3e-41 142.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CBY36220.1 - 0.00089 19.1 0.0 0.0044 16.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY36220.1 - 0.0016 19.1 0.0 0.014 16.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBY36220.1 - 0.0032 17.1 0.1 0.062 12.9 0.0 2.5 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CBY36220.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY36220.1 - 0.027 15.1 0.0 0.64 10.7 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain UPF0154 PF03672.13 CBY36222.1 - 0.053 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RhodobacterPufX PF11511.8 CBY36222.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Intrinsic membrane protein PufX DAG1 PF05454.11 CBY36223.1 - 2.4e-06 27.2 0.3 5.9e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Chordopox_A13L PF05961.11 CBY36223.1 - 0.097 12.9 0.3 0.25 11.6 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Gram_pos_anchor PF00746.21 CBY36223.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5316 PF17247.2 CBY36223.1 - 0.22 11.5 0.3 0.48 10.5 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Arf PF00025.21 CBY36224.1 - 8.3e-56 188.2 0.0 1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY36224.1 - 5.3e-14 52.1 0.0 6.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY36224.1 - 1.9e-13 50.7 0.0 3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY36224.1 - 2.5e-12 46.6 0.0 3.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY36224.1 - 5.7e-10 38.9 0.1 1.3e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY36224.1 - 1.5e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY36224.1 - 0.013 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 CBY36224.1 - 0.059 12.4 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein 6PF2K PF01591.18 CBY36224.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2754 PF10953.8 CBY36224.1 - 0.11 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Pkinase PF00069.25 CBY36225.1 - 1.2e-34 119.9 0.0 1.5e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36225.1 - 1.9e-28 99.4 0.7 9.2e-28 97.2 0.7 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TGF_beta_GS PF08515.12 CBY36225.1 - 4.3e-06 26.1 1.2 6.5e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Transforming growth factor beta type I GS-motif FTA2 PF13095.6 CBY36225.1 - 0.024 14.3 0.5 0.045 13.4 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY36225.1 - 0.024 13.4 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Gal-3-0_sulfotr PF06990.11 CBY36227.1 - 3.6e-61 207.2 0.1 4.7e-61 206.9 0.1 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY36227.1 - 0.0048 16.8 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family DUF4895 PF16236.5 CBY36227.1 - 0.0086 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4895) AA_permease_2 PF13520.6 CBY36228.1 - 1.4e-06 27.4 4.2 1.6e-06 27.3 4.2 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CBY36228.1 - 0.0052 15.9 2.8 0.0058 15.7 2.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3021 PF11457.8 CBY36228.1 - 0.021 15.1 0.7 0.022 15.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) AA_permease PF00324.21 CBY36228.1 - 0.051 12.1 7.2 0.065 11.8 7.2 1.0 1 0 0 1 1 1 0 Amino acid permease Yip1 PF04893.17 CBY36228.1 - 0.47 10.1 5.0 0.55 9.9 5.0 1.0 1 0 0 1 1 1 0 Yip1 domain NOB1_Zn_bind PF08772.11 CBY36230.1 - 0.0026 17.9 0.6 0.0037 17.4 0.6 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4 PF00097.25 CBY36230.1 - 0.0037 17.1 1.3 0.0057 16.5 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RRN7 PF11781.8 CBY36230.1 - 0.01 15.5 0.4 0.017 14.8 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C3HC4_2 PF13923.6 CBY36230.1 - 0.011 15.6 1.8 0.02 14.7 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ephrin_rec_like PF07699.13 CBY36230.1 - 0.022 14.5 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative ephrin-receptor like zf-RING_5 PF14634.6 CBY36230.1 - 0.046 13.7 1.3 0.071 13.1 1.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.6 CBY36230.1 - 0.081 12.7 2.0 0.087 12.6 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain RecR PF02132.15 CBY36230.1 - 0.11 12.1 1.4 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 RecR protein Vps39_2 PF10367.9 CBY36230.1 - 0.72 10.3 3.8 0.78 10.2 2.4 1.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Peptidase_M14 PF00246.24 CBY36231.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase Pkinase PF00069.25 CBY36232.1 - 2.6e-42 145.0 0.0 3.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36232.1 - 4.7e-14 52.3 0.0 6.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36232.1 - 7.9e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY36232.1 - 0.00042 19.7 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY36232.1 - 0.0028 16.7 0.1 0.0043 16.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY36232.1 - 0.011 15.6 0.2 0.033 14.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family eIF_4EBP PF05456.11 CBY36232.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) WD40 PF00400.32 CBY36233.1 - 5.4e-18 65.0 1.4 0.0033 18.2 0.0 6.3 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36233.1 - 1e-08 35.4 0.0 5.4e-05 23.4 0.0 4.4 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY36233.1 - 0.018 14.0 0.0 0.062 12.3 0.0 1.7 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 CBY36233.1 - 0.54 9.9 11.3 1.4 8.6 11.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M16_C PF05193.21 CBY36234.1 - 0.0052 16.8 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain TIM PF00121.18 CBY36235.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Triosephosphate isomerase DUF5638 PF18688.1 CBY36235.1 - 0.085 13.2 0.4 0.66 10.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF3402 PF11882.8 CBY36236.1 - 3.5e-59 201.1 15.0 5.3e-37 128.0 2.6 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CBY36236.1 - 7.1e-12 45.1 2.9 2.3e-10 40.2 2.9 2.4 1 1 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.20 CBY36237.1 - 4e-16 59.3 0.0 4e-16 59.3 0.0 3.2 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Mitofilin PF09731.9 CBY36237.1 - 3.3e-10 39.5 24.7 2.4e-09 36.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Peptidase_M16_C PF05193.21 CBY36237.1 - 4.2e-07 30.1 0.0 2.9e-06 27.4 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain IFT20 PF14931.6 CBY36238.1 - 5.2e-29 100.8 12.5 6e-29 100.6 12.5 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 CBY36238.1 - 0.29 10.4 13.8 0.21 10.9 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MutS_III PF05192.18 CBY36238.1 - 0.77 10.0 6.3 0.97 9.6 6.3 1.1 1 0 0 1 1 1 0 MutS domain III XRCC1_N PF01834.16 CBY36239.1 - 2.4e-27 95.8 0.0 3.2e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 XRCC1 N terminal domain DUF4674 PF15719.5 CBY36239.1 - 0.0099 15.9 1.0 0.016 15.3 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) zf-HC5HC2H_2 PF13832.6 CBY36241.1 - 3.7e-10 39.9 5.8 3.7e-10 39.9 5.8 2.5 2 2 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY36241.1 - 7.1e-09 35.8 4.5 7.1e-09 35.8 4.5 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain SET PF00856.28 CBY36241.1 - 2.2e-07 31.4 0.1 1.4e-06 28.8 0.0 2.1 2 1 0 2 2 2 1 SET domain PHD PF00628.29 CBY36242.1 - 1.8e-19 69.4 54.4 1.9e-09 37.3 15.6 4.8 3 1 1 4 4 4 3 PHD-finger zf-HC5HC2H_2 PF13832.6 CBY36242.1 - 4.1e-09 36.6 7.6 4.1e-09 36.6 7.6 4.2 1 1 2 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY36242.1 - 8.3e-07 29.2 14.5 8.3e-07 29.2 14.5 4.7 1 1 2 4 4 4 1 PHD-like zinc-binding domain HMG_box_2 PF09011.10 CBY36242.1 - 0.0058 17.2 0.1 0.019 15.6 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CBY36242.1 - 0.014 15.8 1.7 0.018 15.4 0.3 1.9 2 0 0 2 2 2 0 HMG (high mobility group) box zf-CCCH_3 PF15663.5 CBY36243.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger containing family Pou PF00157.17 CBY36244.1 - 9.8e-36 121.6 0.1 1.9e-35 120.7 0.1 1.5 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain PIP49_C PF12260.8 CBY36246.1 - 0.00023 20.9 2.5 0.0005 19.8 2.5 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Sulfotransfer_1 PF00685.27 CBY36247.1 - 1.1e-05 25.1 2.0 1.9e-05 24.3 0.8 1.9 1 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36247.1 - 0.002 18.5 0.3 0.0042 17.5 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family Glyoxalase PF00903.25 CBY36247.1 - 0.051 13.8 0.0 0.095 12.9 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Coa1 PF08695.10 CBY36248.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Ank_2 PF12796.7 CBY36249.1 - 0.018 15.6 0.2 0.71 10.5 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) EF-hand_1 PF00036.32 CBY36250.1 - 2.6e-19 67.2 13.6 6.8e-06 25.3 0.6 6.3 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 CBY36250.1 - 2.9e-17 61.0 10.7 6.4e-06 25.7 0.1 6.2 6 0 0 6 6 6 5 EF-hand domain EF-hand_7 PF13499.6 CBY36250.1 - 4.2e-16 59.2 22.5 2.5e-06 27.8 1.7 4.9 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 CBY36250.1 - 6.5e-14 50.7 13.4 0.0055 16.2 0.7 6.0 5 0 0 5 5 5 5 EF hand EF-hand_8 PF13833.6 CBY36250.1 - 0.0015 18.3 20.7 0.35 10.8 0.9 6.1 5 2 0 5 5 5 3 EF-hand domain pair Spa1_C PF18218.1 CBY36250.1 - 0.019 15.3 0.1 0.049 14.0 0.1 1.6 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain SPARC_Ca_bdg PF10591.9 CBY36250.1 - 0.074 13.4 12.1 0.32 11.3 0.2 3.2 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Borrelia_REV PF03978.13 CBY36250.1 - 0.42 10.6 6.7 0.078 12.9 0.9 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Excalibur PF05901.11 CBY36250.1 - 0.45 11.2 1.7 1e+02 3.6 0.0 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain PHO4 PF01384.20 CBY36251.1 - 9.7e-115 383.2 10.4 1.2e-114 382.9 10.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family QSOX_Trx1 PF18108.1 CBY36252.1 - 0.13 12.4 0.8 1.5 9.0 0.0 2.3 2 1 0 2 2 2 0 QSOX Trx-like domain GCV_H PF01597.19 CBY36253.1 - 2.8e-44 149.9 0.5 3.4e-44 149.7 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CBY36253.1 - 8.7e-06 25.6 0.1 1.3e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 CBY36253.1 - 4.9e-05 23.1 3.0 8.8e-05 22.3 2.2 1.8 1 1 1 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY36253.1 - 0.061 13.1 1.3 3.9 7.4 0.2 2.8 2 1 1 3 3 3 0 Biotin-lipoyl like AAA PF00004.29 CBY36254.1 - 5.6e-95 314.8 0.0 7.6e-47 159.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY36254.1 - 7.6e-22 76.9 3.9 7.4e-10 38.5 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CBY36254.1 - 9.1e-19 67.4 0.5 1.5e-17 63.6 0.3 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CBY36254.1 - 6.7e-14 51.9 0.0 2.2e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBY36254.1 - 3.7e-12 47.0 0.2 0.00064 20.1 0.0 3.9 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CBY36254.1 - 7.8e-12 45.6 0.0 3.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBY36254.1 - 9.9e-11 42.0 0.0 5.3e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CBY36254.1 - 2.9e-10 40.3 0.1 8e-05 22.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY36254.1 - 8.4e-10 39.1 0.3 0.01 16.1 0.1 3.8 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 CBY36254.1 - 3.9e-09 36.2 0.0 0.00038 19.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CBY36254.1 - 2e-08 34.4 0.0 0.0025 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CBY36254.1 - 8.2e-08 32.1 0.6 2.3e-05 24.3 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 CBY36254.1 - 1e-07 32.5 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CBY36254.1 - 3.4e-07 29.9 0.1 0.021 14.2 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY36254.1 - 3.5e-07 30.1 0.1 0.039 13.7 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.17 CBY36254.1 - 4e-07 29.7 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 CBY36254.1 - 6.7e-07 29.7 0.0 0.0068 16.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase ABC_tran PF00005.27 CBY36254.1 - 5.4e-06 27.0 0.0 0.0045 17.5 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 CBY36254.1 - 6.7e-06 25.7 0.0 0.066 12.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 CBY36254.1 - 7.7e-06 26.2 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CBY36254.1 - 1.2e-05 24.8 1.2 1.9 7.8 0.0 3.6 4 0 0 4 4 3 2 KaiC Parvo_NS1 PF01057.17 CBY36254.1 - 1.3e-05 24.4 0.1 0.035 13.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 CBY36254.1 - 1.5e-05 25.0 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 CBY36254.1 - 1.7e-05 25.2 0.0 0.73 10.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CBY36254.1 - 3.6e-05 23.4 1.9 1.8 8.1 0.0 3.7 2 2 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CBY36254.1 - 5.6e-05 22.9 0.0 0.45 10.2 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CBY36254.1 - 6.9e-05 22.7 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CBY36254.1 - 7e-05 22.6 0.0 0.2 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CBY36254.1 - 8.4e-05 22.6 0.2 0.2 11.5 0.0 3.6 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea TsaE PF02367.17 CBY36254.1 - 0.00013 22.0 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CBY36254.1 - 0.00019 20.7 0.0 0.033 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CBY36254.1 - 0.00026 20.3 0.0 0.52 9.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin ResIII PF04851.15 CBY36254.1 - 0.00031 20.8 0.0 0.064 13.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CBY36254.1 - 0.00051 20.2 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CBY36254.1 - 0.00054 19.9 0.1 0.29 11.0 0.0 3.3 3 1 1 4 4 4 1 NACHT domain PhoH PF02562.16 CBY36254.1 - 0.00057 19.4 0.5 1 8.7 0.2 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 CBY36254.1 - 0.00062 19.6 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CBY36254.1 - 0.00067 18.9 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain UFD1 PF03152.14 CBY36254.1 - 0.0018 17.8 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2075 PF09848.9 CBY36254.1 - 0.0028 17.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CBY36254.1 - 0.0042 17.4 0.3 2.7 8.3 0.3 2.8 2 1 1 3 3 2 1 AAA domain NTPase_1 PF03266.15 CBY36254.1 - 0.0043 17.0 1.1 5.3 6.9 0.0 4.2 3 1 0 4 4 4 0 NTPase AAA_11 PF13086.6 CBY36254.1 - 0.005 16.7 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 CBY36254.1 - 0.0054 16.9 0.0 0.72 10.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 CBY36254.1 - 0.0061 16.5 0.0 0.95 9.4 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 CBY36254.1 - 0.033 13.9 0.4 5.1 6.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CBY36254.1 - 0.051 13.3 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.22 CBY36254.1 - 0.057 13.5 0.0 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CBY36254.1 - 0.072 12.8 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 CBY36254.1 - 0.078 12.4 0.0 14 5.0 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein T2SSE PF00437.20 CBY36254.1 - 0.078 12.0 0.0 5.5 6.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Romo1 PF10247.9 CBY36255.1 - 4.7e-14 52.5 18.1 5.9e-14 52.2 18.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 CBY36255.1 - 0.0032 17.8 8.0 0.0036 17.7 8.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3169 PF11368.8 CBY36255.1 - 2.9 7.3 6.2 3.8 7.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) LRR_4 PF12799.7 CBY36257.1 - 2.2e-14 53.3 9.7 9.3e-05 22.7 0.1 5.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY36257.1 - 3.1e-10 39.8 3.5 2.1e-09 37.1 1.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBY36257.1 - 7.2e-09 35.3 8.8 0.00066 19.4 0.4 4.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 CBY36257.1 - 0.0083 16.5 0.4 44 5.2 0.0 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat Carbpep_Y_N PF05388.11 CBY36257.1 - 0.13 12.8 2.5 0.13 12.8 0.3 2.1 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide LRR_6 PF13516.6 CBY36257.1 - 0.13 12.3 3.6 5.6 7.3 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 CBY36258.1 - 5.2e-33 112.5 52.1 2.3e-08 34.2 1.5 10.4 4 4 6 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY36258.1 - 5.5e-24 83.7 51.1 1.8e-08 34.0 3.3 9.3 6 3 1 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 CBY36258.1 - 2.4e-18 66.2 26.2 8.5e-12 44.9 2.9 5.7 4 2 2 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.6 CBY36258.1 - 1.2e-11 43.7 34.3 1.3 9.3 0.1 13.0 15 0 0 15 15 15 6 Leucine Rich repeat LRR_1 PF00560.33 CBY36258.1 - 0.028 14.9 49.1 1.8 9.4 0.4 11.2 10 5 0 10 10 10 0 Leucine Rich Repeat LRR_2 PF07723.13 CBY36258.1 - 0.14 12.8 15.3 39 5.2 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_9 PF14580.6 CBY36259.1 - 2.6e-11 43.4 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY36259.1 - 7.6e-08 32.5 0.4 6.1e-06 26.5 0.2 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY36259.1 - 0.0084 15.9 0.7 0.027 14.2 0.7 1.9 1 1 0 1 1 1 1 Leucine rich repeat PRA1 PF03208.19 CBY36260.1 - 1.5e-26 92.8 0.4 1.8e-26 92.5 0.4 1.0 1 0 0 1 1 1 1 PRA1 family protein 2TM PF13239.6 CBY36260.1 - 3.8 7.9 6.7 22 5.5 6.7 2.1 1 1 0 1 1 1 0 2TM domain DUF726 PF05277.12 CBY36261.1 - 2.3e-96 322.7 2.7 3e-96 322.3 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SAVED PF18145.1 CBY36261.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain DUF900 PF05990.12 CBY36261.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2207 PF09972.9 CBY36261.1 - 0.022 13.5 0.4 0.031 13.0 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 CBY36261.1 - 0.034 14.2 0.2 0.034 14.2 0.2 2.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3040 PF11239.8 CBY36261.1 - 0.038 14.3 0.1 0.038 14.3 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) CBP_BcsR PF10945.8 CBY36261.1 - 0.16 11.4 0.1 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsR Phage_holin_3_6 PF07332.11 CBY36261.1 - 0.22 11.6 8.1 0.37 10.9 4.4 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Mito_carr PF00153.27 CBY36262.1 - 2.3e-44 149.2 6.9 1.2e-17 63.5 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Snurportin1 PF11538.8 CBY36263.1 - 0.0082 16.3 4.8 0.019 15.1 4.8 1.6 1 0 0 1 1 1 1 Snurportin1 Ig_3 PF13927.6 CBY36264.1 - 2.3e-07 31.3 5.4 0.00021 21.8 0.2 4.0 3 1 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CBY36264.1 - 5.7e-07 29.8 1.8 0.02 15.2 0.5 3.1 3 1 0 3 3 3 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY36264.1 - 1e-05 25.5 10.9 3.4e-05 23.8 0.8 3.7 2 1 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY36264.1 - 9.8e-05 22.5 8.9 0.00052 20.1 0.6 4.3 3 2 0 3 3 3 1 Immunoglobulin domain DUF3439 PF11921.8 CBY36264.1 - 2.5 8.1 7.4 6.4 6.8 7.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MFS_1 PF07690.16 CBY36265.1 - 2.1e-12 46.7 14.9 2.1e-12 46.7 14.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Ion_trans PF00520.31 CBY36266.1 - 1.6e-33 115.9 6.0 1.9e-33 115.7 6.0 1.0 1 0 0 1 1 1 1 Ion transport protein TMEM187 PF15100.6 CBY36266.1 - 0.011 15.3 0.5 0.014 15.0 0.5 1.2 1 0 0 1 1 1 0 TMEM187 protein family PKD_channel PF08016.12 CBY36266.1 - 0.045 12.4 7.3 0.72 8.5 0.5 2.0 2 0 0 2 2 2 0 Polycystin cation channel Ank_4 PF13637.6 CBY36268.1 - 7.3e-13 48.8 0.2 0.0014 19.1 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY36268.1 - 1.6e-11 44.7 0.2 4.5e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY36268.1 - 1.7e-08 34.5 0.1 0.021 15.1 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY36268.1 - 1.4e-06 28.2 0.1 0.57 10.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 CBY36268.1 - 9.4e-06 25.9 0.2 0.11 13.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat zf-C2H2 PF00096.26 CBY36269.1 - 4.1e-05 23.8 6.0 0.0044 17.4 1.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY36269.1 - 0.001 19.4 5.0 0.0097 16.3 0.7 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY36269.1 - 0.011 16.0 5.4 1.7 9.0 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY36269.1 - 0.018 15.5 1.5 0.018 15.5 1.5 3.0 2 1 1 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY36269.1 - 0.031 15.1 0.2 0.031 15.1 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EGF_2 PF07974.13 CBY36270.1 - 0.053 13.9 2.9 0.053 13.9 2.9 3.4 2 1 0 2 2 2 0 EGF-like domain MamL-1 PF09596.10 CBY36271.1 - 0.27 11.5 5.0 0.49 10.7 5.0 1.4 1 0 0 1 1 1 0 MamL-1 domain DUF2013 PF09431.10 CBY36274.1 - 8.8e-29 100.4 2.4 1.4e-28 99.8 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MMS22L_C PF14911.6 CBY36274.1 - 0.00036 19.7 0.8 0.00053 19.2 0.8 1.2 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal DBI_PRT PF02277.17 CBY36274.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyltransferase Homeodomain PF00046.29 CBY36275.1 - 3.8e-20 71.5 1.2 9.1e-20 70.3 1.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY36275.1 - 0.019 14.9 0.2 0.04 13.8 0.2 1.5 1 0 0 1 1 1 0 Homeobox KN domain Ifi-6-16 PF06140.13 CBY36276.1 - 3.8e-06 26.7 1.1 6e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Glyco_transf_10 PF00852.19 CBY36277.1 - 2.2e-44 151.3 3.2 3.3e-44 150.7 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY36277.1 - 1.4e-15 57.7 0.3 4.8e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal FAM176 PF14851.6 CBY36277.1 - 0.00057 19.6 2.9 0.0014 18.3 2.9 1.6 1 0 0 1 1 1 1 FAM176 family Leader_CPA1 PF08252.11 CBY36277.1 - 0.11 11.9 0.1 0.29 10.5 0.1 1.7 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide DUF1515 PF07439.11 CBY36277.1 - 0.2 11.7 2.5 1.6 8.8 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Zip PF02535.22 CBY36277.1 - 3.3 6.9 5.3 4.4 6.4 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2371 PF10177.9 CBY36278.1 - 3e-08 33.9 2.9 0.00027 21.1 0.1 2.7 3 0 0 3 3 3 2 Uncharacterised conserved protein (DUF2371) DUF973 PF06157.11 CBY36278.1 - 0.00014 21.1 0.4 0.00047 19.3 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF973) DUF373 PF04123.13 CBY36278.1 - 0.0034 16.9 0.3 0.0046 16.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF981 PF06168.11 CBY36278.1 - 0.015 15.2 1.6 0.021 14.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) PIRT PF15099.6 CBY36278.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Oxidored_q4 PF00507.19 CBY36278.1 - 0.054 13.6 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF202 PF02656.15 CBY36278.1 - 2 8.9 4.3 19 5.8 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 CBY36278.1 - 2.9 7.5 8.0 0.19 11.4 2.8 1.6 2 0 0 2 2 2 0 Tetraspanin family Pkinase PF00069.25 CBY36279.1 - 1.6e-51 175.2 0.1 2.6e-51 174.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36279.1 - 6e-28 97.8 0.0 9.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36279.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY36279.1 - 0.00082 18.8 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY36279.1 - 0.0023 16.8 0.0 0.0023 16.8 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CBY36279.1 - 0.016 14.8 0.2 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Actin PF00022.19 CBY36280.1 - 4.7e-109 364.7 0.0 5.2e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 Actin FtsA PF14450.6 CBY36280.1 - 0.042 14.3 0.1 0.21 12.0 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA RNase_T PF00929.24 CBY36281.1 - 0.00044 20.8 0.1 0.0031 18.1 0.1 2.2 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.18 CBY36282.1 - 6.2e-06 26.2 10.0 1.7e-05 24.8 10.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CBY36282.1 - 0.0053 17.0 6.9 0.055 13.8 3.0 2.7 1 1 1 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Tup_N PF08581.10 CBY36282.1 - 0.018 15.3 6.8 0.018 15.3 6.8 2.5 2 0 0 2 2 2 0 Tup N-terminal PKcGMP_CC PF16808.5 CBY36282.1 - 0.13 12.2 0.4 0.13 12.2 0.4 4.2 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 CBY36282.1 - 0.76 9.9 28.2 9.8 6.2 12.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Ferritin PF00210.24 CBY36282.1 - 0.76 9.7 8.4 0.53 10.2 6.3 1.8 1 1 0 1 1 1 0 Ferritin-like domain DUF1664 PF07889.12 CBY36282.1 - 3.9 7.5 9.5 3 7.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 CBY36282.1 - 7.6 5.3 11.2 8.9 5.1 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EF1G PF00647.19 CBY36283.1 - 1.1e-38 131.5 0.1 2.8e-38 130.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBY36283.1 - 1.8e-15 56.9 0.1 4.3e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY36283.1 - 2.2e-07 30.8 0.0 6.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY36283.1 - 2.6e-07 30.9 0.0 8.2e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY36283.1 - 2.2e-06 27.8 0.0 9.4e-06 25.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SKIP_SNW PF02731.15 CBY36284.1 - 0.025 14.2 5.7 0.025 14.2 5.7 2.3 2 0 0 2 2 2 0 SKIP/SNW domain Plasmodium_Vir PF05795.11 CBY36284.1 - 0.23 10.8 1.9 0.33 10.3 1.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FerA PF08165.11 CBY36286.1 - 0.067 13.2 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 FerA (NUC095) domain AAA PF00004.29 CBY36287.1 - 7e-40 136.5 0.0 1.7e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY36287.1 - 1.5e-12 47.3 0.1 1.4e-11 44.2 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Rad60-SLD PF11976.8 CBY36287.1 - 3.2e-09 36.5 0.1 1.1e-08 34.8 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like AAA_lid_3 PF17862.1 CBY36287.1 - 7.3e-09 35.3 0.0 4.8e-08 32.7 0.0 2.4 1 1 0 1 1 1 1 AAA+ lid domain ubiquitin PF00240.23 CBY36287.1 - 6.4e-05 22.6 0.6 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family RuvB_N PF05496.12 CBY36287.1 - 7.1e-05 22.6 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY36287.1 - 0.00031 20.9 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBY36287.1 - 0.00041 20.5 0.1 0.002 18.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBY36287.1 - 0.0016 17.7 0.0 0.0042 16.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CBY36287.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBY36287.1 - 0.0051 16.8 0.1 0.038 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBY36287.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBY36287.1 - 0.0067 16.7 0.2 0.11 12.7 0.1 2.7 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CBY36287.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBY36287.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBY36287.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY36287.1 - 0.055 13.0 0.1 0.16 11.5 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY36287.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CBY36287.1 - 0.098 12.0 0.0 3 7.1 0.1 2.7 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 CBY36287.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 CBY36287.1 - 0.17 11.7 3.8 0.24 11.1 0.4 2.5 2 1 0 2 2 2 0 AAA domain Macoilin PF09726.9 CBY36287.1 - 0.72 8.3 6.7 1.6 7.2 0.1 2.1 2 0 0 2 2 2 0 Macoilin family AAA_18 PF13238.6 CBY36287.1 - 0.87 10.1 4.5 0.36 11.4 0.5 2.5 2 1 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.7 CBY36288.1 - 2.7e-18 66.2 0.0 5.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBY36288.1 - 2.3e-10 40.8 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 CBY36288.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease DOMON PF03351.17 CBY36289.1 - 2.1e-12 47.3 0.2 3.3e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CBY36289.1 - 8.4e-08 32.4 1.1 8.4e-08 32.4 1.1 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 CBY36289.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 CBY36289.1 - 0.0057 16.5 0.1 0.0057 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ODV-E18 PF10717.9 CBY36289.1 - 0.12 12.2 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4079 PF13301.6 CBY36289.1 - 0.15 12.3 5.9 0.026 14.7 1.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CBY36289.1 - 1.2 8.7 11.8 12 5.5 11.8 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 XK-related PF09815.9 CBY36290.1 - 1.4e-73 247.9 25.4 1.6e-73 247.7 25.4 1.1 1 0 0 1 1 1 1 XK-related protein DUF4131 PF13567.6 CBY36290.1 - 7.9 6.1 10.1 0.3 10.7 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Casc1_N PF15927.5 CBY36291.1 - 0.15 11.8 13.8 0.16 11.7 13.8 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus adh_short PF00106.25 CBY36292.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_10 PF00852.19 CBY36295.1 - 3.5e-45 153.9 0.9 4.6e-45 153.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY36295.1 - 0.0025 18.2 0.1 0.0052 17.2 0.1 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Tim54 PF11711.8 CBY36296.1 - 0.018 13.8 5.3 0.023 13.5 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Borrelia_P83 PF05262.11 CBY36296.1 - 0.028 12.9 5.9 0.035 12.6 5.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 CBY36296.1 - 0.036 12.9 3.0 0.049 12.4 3.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP90 PF00183.18 CBY36296.1 - 0.12 11.3 8.0 0.19 10.6 8.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF4512 PF14975.6 CBY36296.1 - 0.12 13.2 1.1 0.3 11.9 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RR_TM4-6 PF06459.12 CBY36296.1 - 0.22 11.3 7.5 0.33 10.7 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CBY36296.1 - 0.24 11.8 4.1 0.39 11.1 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sulfotransfer_1 PF00685.27 CBY36299.1 - 7.7e-14 51.8 2.2 1.3e-13 51.0 2.2 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36299.1 - 8.2e-06 26.4 0.3 0.024 15.0 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY36300.1 - 4.1e-12 46.1 0.0 6.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Succ_DH_flav_C PF02910.20 CBY36305.1 - 3.8e-16 59.2 0.1 4.3e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Metallophos PF00149.28 CBY36306.1 - 1.6e-10 41.8 0.8 2.6e-10 41.1 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY36306.1 - 3.9e-06 27.1 0.0 0.00027 21.2 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.23 CBY36307.1 - 4.4e-57 193.8 0.8 6.8e-57 193.2 0.8 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CBY36307.1 - 4.5e-06 26.9 0.3 2.4e-05 24.5 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 CBY36307.1 - 0.00022 21.9 3.0 0.0024 18.6 2.0 2.7 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 CBY36307.1 - 0.012 14.2 0.1 0.071 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CBY36307.1 - 0.062 12.9 0.9 0.38 10.3 0.9 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase EF-hand_6 PF13405.6 CBY36308.1 - 5.4e-07 29.0 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY36308.1 - 1.6e-06 27.3 0.0 0.0054 16.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY36308.1 - 0.00016 22.1 0.0 0.048 14.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY36308.1 - 0.015 14.8 0.0 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 EF hand KinB_sensor PF16767.5 CBY36309.1 - 0.1 13.1 5.0 5.9 7.4 0.1 2.9 2 1 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB TMPIT PF07851.13 CBY36309.1 - 1.7 7.8 5.7 3.6 6.7 5.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein MRPL52 PF18699.1 CBY36309.1 - 3 8.1 6.4 38 4.6 0.0 3.0 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Sushi PF00084.20 CBY36310.1 - 1.3e-12 48.1 39.6 1.5e-07 31.9 3.7 5.1 5 0 0 5 5 5 3 Sushi repeat (SCR repeat) DUF2457 PF10446.9 CBY36310.1 - 0.11 11.7 6.6 0.17 11.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF966 PF06136.13 CBY36310.1 - 1.2 8.7 9.0 0.087 12.5 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF966) CUB PF00431.20 CBY36311.1 - 1.5e-177 578.9 23.4 4.4e-23 81.7 0.0 14.2 14 0 0 14 14 14 14 CUB domain CUB_2 PF02408.20 CBY36311.1 - 5.9 6.7 20.7 1.2 8.9 0.3 6.9 5 1 1 6 6 6 0 CUB-like domain HGTP_anticodon PF03129.20 CBY36313.1 - 2.7e-17 62.7 0.0 9.2e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.20 CBY36313.1 - 1.3e-10 41.2 7.2 3.1e-10 40.0 7.2 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 CBY36313.1 - 9e-10 38.8 0.0 1.1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2996 PF11210.8 CBY36313.1 - 0.088 13.2 0.6 0.36 11.3 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) DUF5321 PF17254.2 CBY36314.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5321) UPAR_LY6_2 PF16975.5 CBY36315.1 - 2.3e-41 140.3 14.1 3e-41 139.9 14.1 1.1 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 Kelch_6 PF13964.6 CBY36316.1 - 0.0048 17.1 2.4 1.2 9.5 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Gal_Lectin PF02140.18 CBY36317.1 - 0.017 15.5 2.6 0.032 14.6 2.6 1.5 1 0 0 1 1 1 0 Galactose binding lectin domain ATF7IP_BD PF16788.5 CBY36317.1 - 1.3 9.0 12.3 1.7 8.7 12.3 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain zf-RING_2 PF13639.6 CBY36318.1 - 5.6e-10 39.4 9.1 9.3e-10 38.7 8.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY36318.1 - 5.5e-08 32.6 6.6 1.5e-07 31.1 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY36318.1 - 1.4e-07 31.4 1.1 4e-07 30.0 1.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY36318.1 - 4.3e-07 29.7 10.9 1.1e-06 28.4 8.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY36318.1 - 9.8e-07 28.7 4.3 1.7e-06 27.9 3.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY36318.1 - 7.3e-06 26.2 6.6 7.3e-06 26.2 6.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CBY36318.1 - 1.2e-05 25.0 7.1 2.9e-05 23.8 7.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CBY36318.1 - 1.5e-05 24.8 8.9 1.5e-05 24.8 8.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY36318.1 - 4.3e-05 23.6 3.7 4.3e-05 23.6 3.7 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY36318.1 - 0.00012 21.8 9.6 0.00025 20.8 8.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY36318.1 - 0.0013 18.5 8.3 0.0039 17.0 8.3 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY36318.1 - 0.0065 16.3 1.3 0.017 14.9 1.3 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein WD40_alt PF14077.6 CBY36318.1 - 0.049 13.5 0.2 0.049 13.5 0.2 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif Zn_ribbon_17 PF17120.5 CBY36318.1 - 0.07 12.8 6.8 0.16 11.6 6.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 CBY36318.1 - 0.45 10.6 8.1 3.1 7.9 8.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon DASH_Dam1 PF08653.10 CBY36318.1 - 0.81 9.5 2.6 17 5.3 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 IBR PF01485.21 CBY36318.1 - 0.98 9.7 10.9 27 5.1 11.1 2.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.5 CBY36318.1 - 2.5 8.3 8.2 2.7 8.2 5.4 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 ADIP PF11559.8 CBY36318.1 - 2.9 7.9 33.1 3.3 7.8 13.2 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding FYVE PF01363.21 CBY36318.1 - 3.2 7.9 10.5 5.6 7.2 8.5 2.4 2 1 0 2 2 2 0 FYVE zinc finger LMBR1 PF04791.16 CBY36318.1 - 6.8 5.5 12.1 10 4.9 12.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Homeodomain PF00046.29 CBY36319.1 - 4.6e-21 74.4 7.7 9.4e-21 73.4 7.7 1.6 1 0 0 1 1 1 1 Homeodomain RNA_pol_Rpc4 PF05132.14 CBY36319.1 - 0.069 13.6 3.1 0.1 13.0 3.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 CBY36319.1 - 0.3 11.0 14.0 0.5 10.3 14.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 CBY36319.1 - 0.91 8.2 5.9 1.4 7.6 5.9 1.3 1 0 0 1 1 1 0 Presenilin DUF4632 PF15451.6 CBY36319.1 - 1.2 9.3 4.3 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) FAM176 PF14851.6 CBY36319.1 - 1.2 8.8 6.2 2.4 7.8 6.2 1.6 1 0 0 1 1 1 0 FAM176 family ABC_trans_N PF14510.6 CBY36319.1 - 1.6 9.4 4.6 3.5 8.3 4.6 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal Connexin PF00029.19 CBY36319.1 - 3.4 7.3 5.6 6 6.6 5.6 1.4 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 CBY36319.1 - 6 6.6 13.3 10 5.8 13.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.6 CBY36319.1 - 8.9 6.8 14.3 1.9 8.9 9.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TB2_DP1_HVA22 PF03134.19 CBY36320.1 - 1.9e-29 101.4 5.6 3.3e-29 100.6 5.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TMEM220 PF15071.6 CBY36320.1 - 5.3 7.9 6.9 58 4.5 5.8 2.7 2 1 0 2 2 2 0 Transmembrane family 220, helix ABC_tran PF00005.27 CBY36321.1 - 3.2e-46 157.3 0.0 4.9e-29 101.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBY36321.1 - 2.2e-40 139.1 19.8 2.6e-23 83.1 2.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBY36321.1 - 1.6e-11 44.1 0.0 0.00018 21.0 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY36321.1 - 6.3e-05 23.4 0.1 0.41 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CBY36321.1 - 0.00019 21.4 1.8 10 5.9 0.0 4.5 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBY36321.1 - 0.00021 21.4 0.7 0.064 13.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY36321.1 - 0.00054 19.9 0.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CBY36321.1 - 0.0045 17.3 1.5 2.3 8.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CBY36321.1 - 0.0089 15.3 0.4 1.4 8.2 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_29 PF13555.6 CBY36321.1 - 0.061 13.1 2.1 5.2 6.9 0.4 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 CBY36321.1 - 0.091 11.8 0.2 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.7 CBY36321.1 - 0.13 11.2 0.4 0.94 8.3 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain TrwB_AAD_bind PF10412.9 CBY36321.1 - 0.2 10.6 0.3 3 6.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 CBY36321.1 - 0.23 11.5 3.4 0.2 11.7 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Acyltransf_C PF16076.5 CBY36322.1 - 0.012 15.7 0.5 0.066 13.3 0.0 2.2 2 1 0 2 2 2 0 Acyltransferase C-terminus AAA_33 PF13671.6 CBY36322.1 - 0.033 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Cluap1 PF10234.9 CBY36323.1 - 0.075 12.4 4.8 0.081 12.3 4.3 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 zf-FCS PF06467.14 CBY36323.1 - 0.082 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Acyltransferase PF01553.21 CBY36324.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4440 PF14534.6 CBY36324.1 - 0.18 12.2 0.0 0.71 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) HAD_2 PF13419.6 CBY36325.1 - 4.6e-15 56.1 0.1 6.2e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY36325.1 - 8e-10 39.4 0.0 1.2e-09 38.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY36325.1 - 3.5e-05 23.8 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CBY36325.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4235 PF14019.6 CBY36325.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Got1 PF04178.12 CBY36326.1 - 6.1e-05 23.4 5.3 9.1e-05 22.9 5.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family RWD PF05773.22 CBY36329.1 - 0.00061 20.1 0.2 0.00082 19.7 0.2 1.3 1 1 0 1 1 1 1 RWD domain KxDL PF10241.9 CBY36329.1 - 0.076 13.3 0.4 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein RIO1 PF01163.22 CBY36331.1 - 1.4e-50 171.5 0.1 3.2e-50 170.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CBY36331.1 - 6.7e-28 96.7 0.2 4e-27 94.2 0.0 2.5 4 0 0 4 4 4 1 Rio2, N-terminal APH PF01636.23 CBY36331.1 - 1.7e-12 47.8 1.3 1.5e-05 25.1 0.0 3.5 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 CBY36331.1 - 1.4e-07 31.1 1.4 0.0087 15.4 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY36331.1 - 4.7e-06 26.2 1.2 1.3e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 CBY36331.1 - 0.0048 16.5 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DHC_N2 PF08393.13 CBY36332.1 - 6e-90 302.2 5.5 1.1e-86 291.5 0.4 2.0 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CBY36333.1 - 8.4e-150 500.1 11.9 8.4e-150 500.1 11.9 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBY36333.1 - 6e-11 42.1 0.4 6e-11 42.1 0.4 3.5 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 PhaP_Bmeg PF09602.10 CBY36333.1 - 0.051 13.5 8.4 0.11 12.5 0.5 3.6 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) EGF_CA PF07645.15 CBY36334.1 - 3.3e-08 33.6 8.2 3.3e-08 33.6 8.2 2.4 2 0 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CBY36334.1 - 0.0046 16.9 0.6 0.0046 16.9 0.6 2.0 2 0 0 2 2 2 1 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY36334.1 - 0.006 16.7 7.0 0.006 16.7 7.0 2.5 2 0 0 2 2 2 1 EGF domain PAN_1 PF00024.26 CBY36335.1 - 0.017 15.1 0.5 0.036 14.0 0.5 1.5 1 0 0 1 1 1 0 PAN domain Aa_trans PF01490.18 CBY36336.1 - 3e-28 98.7 17.1 3.6e-28 98.4 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SpoU_methylas_C PF12105.8 CBY36336.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Ndc1_Nup PF09531.10 CBY36336.1 - 2.8 6.5 6.8 3.7 6.1 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PP2C PF00481.21 CBY36337.1 - 6e-57 193.2 0.0 8.2e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY36337.1 - 4.5e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C CARD_2 PF16739.5 CBY36337.1 - 0.18 11.8 0.1 0.41 10.7 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Pkinase PF00069.25 CBY36338.1 - 1.1e-35 123.2 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36338.1 - 4.7e-12 45.7 0.0 6.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY36338.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY36338.1 - 6.7e-05 22.0 0.0 9.3e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY36338.1 - 0.00099 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY36338.1 - 0.0028 16.5 0.1 0.0049 15.7 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY36338.1 - 0.018 15.0 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY36338.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase O-FucT PF10250.9 CBY36339.1 - 0.0028 17.4 0.1 0.0041 16.9 0.1 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VWA PF00092.28 CBY36340.1 - 6.2e-29 101.5 0.6 6.2e-29 101.5 0.6 5.4 5 1 0 5 5 5 2 von Willebrand factor type A domain SepF PF04472.12 CBY36340.1 - 1 9.7 5.7 7 7.0 0.0 4.7 5 0 0 5 5 5 0 Cell division protein SepF RVT_1 PF00078.27 CBY36341.1 - 1.5e-17 63.9 0.1 3.4e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY36341.1 - 8.7e-12 45.3 0.0 2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 CBY36341.1 - 0.00021 21.5 0.0 0.00077 19.7 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY36341.1 - 0.0042 17.1 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-AD PF07776.15 CBY36341.1 - 0.13 12.5 3.8 2.1 8.7 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF5001 PF16392.5 CBY36341.1 - 0.24 11.3 3.7 1.8 8.5 0.2 3.7 3 0 0 3 3 3 0 Ig-like domain ODAPH PF15848.5 CBY36346.1 - 0.11 12.9 5.4 5.6 7.5 0.2 3.5 3 1 0 3 3 3 0 Odontogenesis associated phosphoprotein TPKR_C2 PF16920.5 CBY36348.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain VCBS PF13517.6 CBY36349.1 - 3.9e-12 46.6 9.0 0.001 19.6 0.2 4.3 4 1 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY36349.1 - 0.018 15.2 9.6 3.2 8.0 0.1 4.7 5 0 0 5 5 5 0 FG-GAP repeat TPR_8 PF13181.6 CBY36350.1 - 2.9e-12 45.7 0.2 0.022 14.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36350.1 - 7.5e-10 38.2 1.9 1.8 8.9 0.0 7.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36350.1 - 3.6e-09 36.7 0.4 0.77 10.7 0.0 6.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY36350.1 - 4.1e-09 35.9 0.2 1.5 8.8 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36350.1 - 1.5e-08 34.4 0.6 0.31 11.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36350.1 - 1.7e-06 28.2 0.5 3.4 8.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36350.1 - 6.9e-06 25.6 3.7 0.04 13.6 0.0 5.3 6 0 0 6 6 6 1 TPR repeat TPR_16 PF13432.6 CBY36350.1 - 2.2e-05 25.0 0.3 3.7 8.3 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY36350.1 - 6.9e-05 23.3 4.9 0.84 10.2 0.1 4.7 5 1 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY36350.1 - 0.00088 19.3 0.3 0.011 15.8 0.0 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 CBY36350.1 - 0.0015 18.7 4.2 1.2 9.4 0.0 4.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36350.1 - 0.0083 16.4 3.3 17 5.8 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY36350.1 - 0.017 14.5 3.6 1.2 8.4 0.3 3.9 4 1 0 4 4 4 0 MalT-like TPR region TPR_10 PF13374.6 CBY36350.1 - 0.088 12.7 0.1 37 4.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36350.1 - 0.18 12.1 4.4 0.48 10.7 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CBY36350.1 - 0.24 12.1 0.8 3.8 8.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2HC_2 PF13913.6 CBY36351.1 - 2.8e-12 46.2 12.5 6.5e-09 35.5 0.2 3.0 3 0 0 3 3 3 2 zinc-finger of a C2HC-type YacG PF03884.14 CBY36351.1 - 0.00042 20.0 1.2 0.00042 20.0 1.2 2.6 3 0 0 3 3 3 1 DNA gyrase inhibitor YacG RNF220 PF15926.5 CBY36351.1 - 0.047 13.3 3.0 0.24 11.0 0.3 2.5 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Rad50_zn_hook PF04423.14 CBY36351.1 - 0.077 12.8 1.7 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 CBY36351.1 - 2.1 8.4 11.7 0.29 11.2 1.4 2.8 3 0 0 3 3 3 0 Double zinc ribbon Phosphodiest PF01663.22 CBY36352.1 - 2.9e-11 43.5 1.9 9.9e-10 38.5 0.5 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CBY36352.1 - 7.9e-06 25.5 0.1 3.7e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 CBY36352.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily ANAPC4_WD40 PF12894.7 CBY36353.1 - 1.4e-05 25.3 0.0 0.014 15.7 0.0 3.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY36354.1 - 3e-16 59.5 0.1 0.00013 22.7 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36354.1 - 4.1e-11 43.0 0.0 0.021 15.1 0.0 4.7 3 3 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY36354.1 - 0.0039 17.1 0.0 0.5 10.2 0.0 2.8 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CBY36354.1 - 0.03 12.9 0.0 0.13 10.7 0.0 2.0 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 CBY36354.1 - 0.14 12.1 0.7 49 4.0 0.0 3.6 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBY36354.1 - 0.18 10.8 0.5 15 4.4 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SNF2_N PF00176.23 CBY36356.1 - 1.6e-33 115.9 0.5 2.3e-33 115.4 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CBY36356.1 - 1.1e-10 41.8 0.3 2.8e-08 33.9 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY36356.1 - 1.5e-05 24.9 0.0 3.5e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 CBY36356.1 - 0.0019 18.2 0.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.6 CBY36356.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RE_MjaI PF09568.10 CBY36356.1 - 0.048 13.5 1.1 0.12 12.2 0.8 1.8 1 1 0 1 1 1 0 MjaI restriction endonuclease DUF5339 PF17274.2 CBY36356.1 - 0.11 13.3 2.0 0.28 12.1 2.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5339) WHEP-TRS PF00458.20 CBY36357.1 - 8.7e-47 157.1 43.6 7.9e-18 64.4 6.1 4.3 4 0 0 4 4 4 3 WHEP-TRS domain ProRS-C_1 PF09180.11 CBY36357.1 - 5.7e-19 68.1 1.3 2e-18 66.4 1.3 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CBY36357.1 - 1.1e-17 64.0 0.1 1.9e-16 60.0 0.0 2.6 1 1 1 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBY36357.1 - 2.9e-16 60.0 0.0 5.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ApbA_C PF08546.11 CBY36357.1 - 0.16 12.2 0.8 58 3.9 0.0 3.6 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal RuvC PF02075.17 CBY36357.1 - 0.85 9.5 2.7 19 5.1 0.1 3.4 4 0 0 4 4 4 0 Crossover junction endodeoxyribonuclease RuvC DUF883 PF05957.13 CBY36359.1 - 0.06 13.9 0.6 0.11 13.1 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YabA PF06156.13 CBY36359.1 - 0.43 11.2 6.6 0.15 12.7 2.6 2.0 1 1 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 CBY36359.1 - 1.4 9.0 9.4 14 5.7 9.4 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain UPF0449 PF15136.6 CBY36359.1 - 1.6 9.3 7.8 9.8 6.7 5.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Sulfatase PF00884.23 CBY36360.1 - 1e-31 110.5 0.1 1.3e-31 110.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phospholip_A2_1 PF00068.19 CBY36361.1 - 3.8e-09 37.0 1.0 3.8e-09 37.0 1.0 1.9 1 1 1 2 2 2 1 Phospholipase A2 Sulfatase PF00884.23 CBY36362.1 - 1.7e-23 83.5 0.0 2.1e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Peptidase_S8 PF00082.22 CBY36362.1 - 0.071 12.4 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Subtilase family zf-RING_2 PF13639.6 CBY36363.1 - 6.2e-07 29.6 4.6 1.4e-06 28.5 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY36363.1 - 1.8e-05 24.7 2.3 5.7e-05 23.1 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY36363.1 - 1.9e-05 24.4 2.6 5.5e-05 22.9 2.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY36363.1 - 0.00056 20.1 3.5 0.0018 18.5 3.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY36363.1 - 0.0011 18.8 4.5 0.0011 18.8 4.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY36363.1 - 0.0023 17.7 4.0 0.0064 16.3 4.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY36363.1 - 0.0028 17.8 0.2 0.0028 17.8 0.2 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBY36363.1 - 0.0048 16.7 3.5 0.012 15.5 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY36363.1 - 0.014 15.4 0.3 0.035 14.1 0.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WD40_alt PF14077.6 CBY36363.1 - 0.033 14.0 2.1 0.046 13.6 0.2 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif Leuk-A4-hydro_C PF09127.11 CBY36363.1 - 0.079 13.0 1.9 0.63 10.1 0.1 2.5 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal IBR PF01485.21 CBY36363.1 - 0.17 12.1 3.8 0.61 10.4 3.8 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 CBY36363.1 - 0.31 10.9 3.6 0.75 9.7 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1192 PF06698.11 CBY36363.1 - 2.5 8.2 7.2 17 5.6 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) ADIP PF11559.8 CBY36363.1 - 6 6.9 41.0 8 6.5 15.2 3.5 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DASH_Dam1 PF08653.10 CBY36363.1 - 6.4 6.7 5.8 15 5.4 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Prefoldin PF02996.17 CBY36364.1 - 7.6e-16 58.1 0.2 1.2e-15 57.5 0.2 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CBY36364.1 - 0.055 13.4 2.6 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBY36364.1 - 0.084 12.9 1.9 7.7 6.6 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1216 PF06746.11 CBY36364.1 - 0.099 12.7 2.4 0.26 11.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) EMP24_GP25L PF01105.24 CBY36365.1 - 0.0043 17.0 1.7 0.0073 16.3 0.3 2.0 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD LD_cluster3 PF18180.1 CBY36365.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster3 family NOGCT PF08155.11 CBY36365.1 - 0.069 13.1 0.1 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NOGCT (NUC087) domain EB PF01683.18 CBY36365.1 - 0.078 13.3 16.8 0.13 12.6 3.1 2.6 2 0 0 2 2 2 0 EB module EGF PF00008.27 CBY36365.1 - 0.27 11.6 14.2 0.4 11.0 1.8 2.7 2 0 0 2 2 2 0 EGF-like domain cEGF PF12662.7 CBY36365.1 - 1 9.4 7.8 2.4 8.2 1.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like TIL PF01826.17 CBY36365.1 - 4.3 7.7 17.2 0.46 10.8 2.2 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Tme5_EGF_like PF09064.10 CBY36365.1 - 5.7 6.9 14.6 0.32 10.9 1.0 2.9 2 1 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like hEGF PF12661.7 CBY36365.1 - 9.3 7.1 13.2 19 6.1 3.0 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF VWA PF00092.28 CBY36366.1 - 5.1e-28 98.5 0.2 1.7e-27 96.8 0.2 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY36366.1 - 3.9e-12 46.7 0.0 1.4e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain FeS_assembly_P PF01883.19 CBY36366.1 - 0.0057 16.8 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 2 Iron-sulfur cluster assembly protein EMP24_GP25L PF01105.24 CBY36366.1 - 0.011 15.7 0.2 0.024 14.6 0.2 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD EB PF01683.18 CBY36366.1 - 0.072 13.4 14.9 0.18 12.1 3.4 2.8 2 0 0 2 2 2 0 EB module cEGF PF12662.7 CBY36366.1 - 7 6.7 7.9 6.4 6.8 1.6 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 CBY36366.1 - 9.8 6.6 13.0 0.55 10.6 3.8 2.9 2 1 0 2 2 2 0 Pvs28 EGF domain Kelch_6 PF13964.6 CBY36367.1 - 0.01 16.1 2.9 1.4 9.3 0.0 3.3 4 0 0 4 4 4 0 Kelch motif IPP-2 PF04979.14 CBY36368.1 - 2.9e-22 79.8 9.7 5.4e-22 78.9 9.7 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) MRP-S23 PF10484.9 CBY36368.1 - 0.051 13.8 1.2 0.32 11.2 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Sulfakinin PF08257.11 CBY36368.1 - 0.63 10.3 0.3 0.63 10.3 0.3 2.3 2 0 0 2 2 2 0 Sulfakinin family HYLS1_C PF15311.6 CBY36370.1 - 1e-25 90.3 1.1 1e-25 90.3 1.1 1.9 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.9 CBY36370.1 - 0.049 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Allexi_40kDa PF05549.11 CBY36370.1 - 0.1 12.1 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein HEAT PF02985.22 CBY36371.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 HEAT repeat Adaptin_N PF01602.20 CBY36371.1 - 0.14 10.7 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region CLASP_N PF12348.8 CBY36372.1 - 9.5e-30 103.8 2.6 6.3e-27 94.6 3.0 2.8 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 CBY36372.1 - 0.0005 20.1 3.4 0.032 14.3 0.6 3.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBY36372.1 - 0.0021 16.7 10.7 0.24 9.9 1.0 4.8 3 2 1 5 5 5 2 Adaptin N terminal region HEAT PF02985.22 CBY36372.1 - 0.0057 16.8 15.8 12 6.5 0.0 8.2 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 CBY36372.1 - 0.052 13.9 8.0 3 8.3 0.0 5.5 5 1 2 7 7 7 0 HEAT repeats UMP1 PF05348.11 CBY36373.1 - 3.1e-05 24.2 0.0 3.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Clathrin PF00637.20 CBY36375.1 - 6.1e-196 642.2 36.9 1e-33 116.2 1.6 7.9 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CBY36375.1 - 4.4e-41 137.2 4.0 2.9e-07 30.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CBY36375.1 - 8.2e-29 99.3 4.4 1.2e-28 98.8 0.8 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 CBY36375.1 - 3.4e-10 39.1 0.0 1e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CBY36375.1 - 0.00025 20.2 2.9 0.24 10.4 0.0 3.7 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 CBY36375.1 - 0.02 14.9 9.0 3.9 7.7 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RtcR PF06956.11 CBY36375.1 - 0.031 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase TPR_12 PF13424.6 CBY36375.1 - 0.051 13.9 2.7 41 4.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36375.1 - 0.14 12.4 9.9 0.46 10.8 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36375.1 - 0.22 11.8 5.3 26 5.2 0.0 5.1 4 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY36375.1 - 5.4 7.8 6.4 1.6e+02 3.0 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Glyco_tran_28_C PF04101.16 CBY36376.1 - 2.3e-23 83.0 0.0 2.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain TTL PF03133.15 CBY36377.1 - 4.3e-37 127.8 0.8 7e-37 127.1 0.8 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family FAST_1 PF06743.15 CBY36377.1 - 0.13 12.2 0.9 14 5.7 0.1 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 TPR_1 PF00515.28 CBY36378.1 - 4.6e-12 45.2 11.1 5.9e-05 22.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36378.1 - 1.8e-09 37.0 10.9 0.0023 17.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36378.1 - 1.9e-07 31.6 0.2 0.00052 20.6 2.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36378.1 - 1.1e-06 28.8 3.9 4.8e-06 26.8 0.9 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY36378.1 - 3.8e-06 26.5 1.7 0.079 13.0 0.6 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36378.1 - 5.2e-06 26.0 7.0 0.00013 21.5 0.9 3.2 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 CBY36378.1 - 4.6e-05 23.9 2.4 0.0071 16.8 2.8 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36378.1 - 0.0013 19.4 0.4 11 7.2 0.3 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36378.1 - 0.0066 16.7 4.8 0.1 13.0 1.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY36378.1 - 0.015 15.5 0.1 0.056 13.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36378.1 - 0.096 12.9 8.4 1.2 9.6 1.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36378.1 - 1 9.6 10.1 17 5.7 0.2 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C2H2_jaz PF12171.8 CBY36379.1 - 3.2e-06 27.3 0.6 7.3e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY36379.1 - 0.0013 19.0 0.3 0.0026 18.1 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY36379.1 - 0.0023 17.7 3.8 0.0088 15.8 3.8 2.0 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY36379.1 - 0.0047 17.2 2.7 0.02 15.2 1.3 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) RNase_T PF00929.24 CBY36379.1 - 0.043 14.4 0.1 0.12 12.9 0.1 1.9 1 1 0 1 1 1 0 Exonuclease MRNIP PF15749.5 CBY36379.1 - 3 8.6 18.3 0.035 14.8 6.0 2.8 2 1 0 2 2 2 0 MRN-interacting protein bZIP_1 PF00170.21 CBY36380.1 - 1.3e-09 38.0 10.7 1.3e-09 38.0 10.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY36380.1 - 2.5e-07 30.6 11.5 2.5e-07 30.6 11.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY36380.1 - 0.0099 16.4 3.2 0.0099 16.4 3.2 2.4 2 1 0 2 2 2 1 bZIP Maf transcription factor TarH PF02203.15 CBY36380.1 - 0.014 15.4 1.6 0.03 14.2 1.6 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue YabA PF06156.13 CBY36380.1 - 8 7.2 14.2 0.25 12.0 3.9 2.6 2 1 0 2 2 2 0 Initiation control protein YabA Histone PF00125.24 CBY36381.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Squash PF00299.18 CBY36381.1 - 0.61 10.2 2.3 2.2 8.4 0.9 2.1 2 0 0 2 2 2 0 Squash family serine protease inhibitor Lectin_C PF00059.21 CBY36382.1 - 2.3e-17 63.7 0.8 3.2e-17 63.2 0.8 1.2 1 0 0 1 1 1 1 Lectin C-type domain Trefoil PF00088.18 CBY36382.1 - 2.9e-09 36.7 4.6 6.8e-09 35.5 4.6 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain Pkinase PF00069.25 CBY36383.1 - 1.1e-19 70.8 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36383.1 - 3.5e-09 36.3 0.0 4.8e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY36383.1 - 0.00091 19.2 0.0 0.0033 17.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 CBY36383.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Glyco_hydro_20 PF00728.22 CBY36384.1 - 2.6e-70 237.6 0.6 3.7e-70 237.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain SET PF00856.28 CBY36385.1 - 1e-13 52.1 0.2 2.4e-10 41.0 0.1 3.1 3 0 0 3 3 3 2 SET domain DUF3390 PF11870.8 CBY36385.1 - 0.033 14.5 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Aminotran_1_2 PF00155.21 CBY36386.1 - 1.7e-26 93.3 0.0 1.9e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tsg PF04668.12 CBY36387.1 - 0.00046 20.9 6.6 0.00046 20.9 6.6 1.7 1 1 0 1 1 1 1 Twisted gastrulation (Tsg) protein conserved region PhzC-PhzF PF02567.16 CBY36388.1 - 1e-52 179.4 0.0 1.2e-52 179.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Resistin PF06954.11 CBY36388.1 - 0.035 14.7 0.0 0.5 11.0 0.0 2.1 2 0 0 2 2 2 0 Resistin N_NLPC_P60 PF12912.7 CBY36388.1 - 0.18 12.2 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term O-FucT PF10250.9 CBY36389.1 - 1e-08 35.3 0.1 2.8e-08 33.9 0.0 1.8 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase bZIP_1 PF00170.21 CBY36390.1 - 1.9e-05 24.7 7.9 5.9e-05 23.1 7.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY36390.1 - 6.3e-05 23.0 6.2 6.3e-05 23.0 6.2 2.5 3 0 0 3 3 3 1 Basic region leucine zipper SUFU_C PF12470.8 CBY36393.1 - 0.016 15.3 3.1 0.018 15.1 3.1 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain HA2 PF04408.23 CBY36394.1 - 1.3e-25 89.8 5.4 7e-25 87.4 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY36394.1 - 1.6e-13 51.0 0.0 8.4e-13 48.6 0.0 2.3 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CBY36394.1 - 7.7e-10 39.0 0.1 1.7e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CBY36394.1 - 2.4e-06 27.9 0.3 1.1e-05 25.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CBY36394.1 - 9.5e-06 25.5 1.3 2.8e-05 24.0 1.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBY36394.1 - 0.0016 18.8 0.2 0.0048 17.2 0.2 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBY36394.1 - 0.0033 16.5 0.1 0.0087 15.1 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBY36394.1 - 0.0037 17.0 0.1 0.0079 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBY36394.1 - 0.032 14.2 0.5 0.27 11.2 0.5 2.3 1 1 0 1 1 1 0 AAA domain DUF5427 PF10310.9 CBY36394.1 - 0.05 12.5 7.8 0.1 11.6 7.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PhoH PF02562.16 CBY36394.1 - 0.068 12.6 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 CBY36394.1 - 0.086 13.4 0.4 1.8 9.1 0.2 2.8 1 1 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 CBY36394.1 - 0.087 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 CBY36394.1 - 0.1 12.2 0.3 0.26 10.9 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4551 PF15087.6 CBY36394.1 - 0.24 10.2 7.2 0.96 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 CBY36394.1 - 0.38 9.0 11.2 0.81 7.9 11.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Band_7 PF01145.25 CBY36395.1 - 4e-27 95.4 1.0 5.3e-27 95.0 1.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CBY36395.1 - 0.0085 16.2 0.4 0.016 15.4 0.4 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 DUF3634 PF12321.8 CBY36397.1 - 0.11 12.9 0.1 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3634) RVT_1 PF00078.27 CBY36398.1 - 3e-14 53.1 0.0 8.8e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY36398.1 - 0.042 13.7 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain G8 PF10162.9 CBY36399.1 - 6.2e-48 161.9 0.0 5.1e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY36399.1 - 3.8e-15 55.7 10.1 3.8e-09 36.5 0.5 3.3 3 0 0 3 3 3 2 IPT/TIG domain Beta_helix PF13229.6 CBY36399.1 - 2.5e-05 24.2 15.1 0.12 12.2 3.1 4.4 2 1 2 4 4 4 4 Right handed beta helix region DUF1344 PF07076.11 CBY36399.1 - 0.037 13.9 0.0 24 5.0 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1344) EcKinase PF02958.20 CBY36400.1 - 0.006 15.9 0.2 0.0083 15.5 0.2 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 CBY36401.1 - 1.4e-12 47.7 0.1 5.6e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CBY36401.1 - 0.039 13.9 0.0 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 CBY36402.1 - 1.8e-25 89.2 0.2 1.3e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain CBFB_NFYA PF02045.15 CBY36403.1 - 2e-28 98.8 3.8 2.6e-28 98.4 3.8 1.2 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DC_STAMP PF07782.13 CBY36403.1 - 0.2 11.4 0.2 0.27 11.0 0.2 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein CDV3 PF15359.6 CBY36405.1 - 0.46 11.0 8.0 0.1 13.1 4.3 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Sugar_tr PF00083.24 CBY36406.1 - 6.1e-31 107.8 10.3 6.9e-31 107.6 10.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY36406.1 - 2e-16 59.9 14.2 2.3e-16 59.7 14.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CBY36406.1 - 0.0018 16.9 3.2 0.0025 16.5 3.2 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Phage_holin_3_2 PF04550.12 CBY36406.1 - 0.81 10.3 5.9 0.96 10.0 1.6 2.5 2 1 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 CBY36407.1 - 6.3e-46 157.2 7.3 2.2e-45 155.4 7.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY36407.1 - 0.00016 20.8 14.2 0.00031 19.8 14.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Gal-3-0_sulfotr PF06990.11 CBY36408.1 - 5.3e-35 121.1 0.4 6.5e-34 117.5 0.4 2.0 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY36408.1 - 2.7e-05 24.2 3.6 7.4e-05 22.8 0.6 3.0 2 1 0 2 2 2 1 Sulfotransferase family DNA_pol3_beta_3 PF02768.15 CBY36408.1 - 0.083 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain BLYB PF05289.11 CBY36408.1 - 0.35 11.1 12.6 2.3 8.5 0.4 2.4 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein DUF1690 PF07956.11 CBY36408.1 - 0.69 10.3 5.0 0.21 12.0 1.1 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) YscO PF07321.12 CBY36409.1 - 0.0026 17.7 2.9 0.0029 17.6 2.3 1.3 1 1 0 1 1 1 1 Type III secretion protein YscO Golgin_A5 PF09787.9 CBY36409.1 - 0.014 14.9 4.9 0.017 14.6 4.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 OrfB_IS605 PF01385.19 CBY36409.1 - 0.15 12.3 2.5 1.5 9.1 1.0 2.1 1 1 1 2 2 2 0 Probable transposase YscO-like PF16789.5 CBY36409.1 - 0.28 11.2 7.7 0.49 10.4 7.7 1.5 1 1 0 1 1 1 0 YscO-like protein DUF4191 PF13829.6 CBY36409.1 - 0.37 10.1 2.1 4.5 6.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) TMF_DNA_bd PF12329.8 CBY36409.1 - 0.96 9.5 12.3 0.12 12.4 1.0 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding LMBR1 PF04791.16 CBY36409.1 - 1.9 7.3 3.5 2.1 7.2 3.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Prefoldin PF02996.17 CBY36409.1 - 3 7.8 7.5 4.1 7.3 0.4 2.9 1 1 1 3 3 3 0 Prefoldin subunit GAGA_bind PF06217.12 CBY36410.1 - 3.7 7.7 7.8 6.9 6.9 7.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 CBY36411.1 - 0.13 10.9 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 Presenilin zf-C4 PF00105.18 CBY36412.1 - 4.1e-30 104.0 11.8 7.7e-30 103.2 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY36412.1 - 7.4e-13 48.6 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Kelch_5 PF13854.6 CBY36413.1 - 3.6e-07 30.0 3.8 1.3 9.1 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CBY36413.1 - 8.5e-05 22.1 4.4 0.054 13.1 0.1 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CBY36413.1 - 0.00029 21.0 7.4 0.42 11.0 0.3 4.8 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 CBY36413.1 - 0.00056 20.1 5.9 0.67 10.3 0.0 5.1 4 2 0 4 4 4 1 Galactose oxidase, central domain DUF3421 PF11901.8 CBY36415.1 - 1.9e-17 63.3 0.0 1.1e-05 25.4 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) Aldedh PF00171.22 CBY36417.1 - 1.1e-60 205.5 0.0 4.8e-44 150.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Lectin_C PF00059.21 CBY36419.1 - 5.6e-29 101.0 9.3 1.3e-18 67.7 1.8 2.4 2 0 0 2 2 2 2 Lectin C-type domain UL45 PF05473.12 CBY36419.1 - 0.0011 18.6 0.6 0.069 12.8 0.2 2.5 2 1 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like HU-CCDC81_euk_2 PF18289.1 CBY36420.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 An_peroxidase PF03098.15 CBY36421.1 - 9.7e-49 166.3 0.0 1.3e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Trypsin PF00089.26 CBY36422.1 - 4.7e-45 154.1 0.8 4.7e-45 154.1 0.8 3.1 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 CBY36422.1 - 2.8e-09 38.0 0.0 9.3e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain Alpha_E3_glycop PF01563.16 CBY36423.1 - 0.024 14.7 0.1 0.068 13.3 0.1 1.7 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein DZF PF07528.14 CBY36424.1 - 1.8e-10 40.9 0.0 2.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DZF domain DUF1690 PF07956.11 CBY36424.1 - 2.4 8.6 8.2 3.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Bromodomain PF00439.25 CBY36425.1 - 1.1e-36 124.8 9.2 4.9e-19 68.2 0.6 2.8 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 CBY36425.1 - 1.4e-25 89.2 0.3 3.2e-25 88.1 0.3 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 CBY36425.1 - 0.034 14.1 0.8 0.034 14.1 0.8 2.5 3 0 0 3 3 3 0 FlxA-like protein Get5_C PF18514.1 CBY36425.1 - 0.18 11.5 0.2 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Get5 C-terminal domain RRM_1 PF00076.22 CBY36426.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 CBY36426.1 - 0.33 9.5 13.0 0.58 8.6 13.0 1.4 1 0 0 1 1 1 0 Macoilin family Tmemb_9 PF05434.11 CBY36427.1 - 2.5e-20 72.9 2.3 2.5e-20 72.9 2.3 2.0 2 1 0 2 2 2 1 TMEM9 MCLC PF05934.11 CBY36427.1 - 0.056 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RRM_1 PF00076.22 CBY36428.1 - 1.6e-12 47.1 0.7 9.6e-10 38.2 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAM PF02893.20 CBY36428.1 - 9.9e-07 28.6 0.0 3.5e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 GRAM domain RRM_Rrp7 PF17799.1 CBY36428.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain CwsA PF10814.8 CBY36428.1 - 1 9.5 4.7 3.4 7.9 3.9 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DUF2126 PF09899.9 CBY36428.1 - 1 7.3 9.3 0.61 8.1 7.4 1.7 2 1 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF3347 PF11827.8 CBY36428.1 - 5 7.3 9.9 15 5.7 9.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PQ-loop PF04193.14 CBY36429.1 - 1.5e-20 72.7 7.4 5.3e-16 58.1 3.5 3.1 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CBY36429.1 - 0.0006 20.7 8.3 0.038 14.8 6.7 2.3 1 1 1 2 2 2 2 ER lumen protein retaining receptor Ferlin_C PF16165.5 CBY36429.1 - 2 8.4 6.5 0.25 11.3 1.2 2.0 1 1 1 2 2 2 0 Ferlin C-terminus Ion_trans PF00520.31 CBY36430.1 - 5.1e-19 68.5 1.1 6e-19 68.2 1.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY36430.1 - 4.4e-14 52.2 5.9 7.1e-14 51.5 5.9 1.3 1 0 0 1 1 1 1 Ion channel FA_desaturase PF00487.24 CBY36430.1 - 0.3 10.9 0.9 0.45 10.3 0.9 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DCX PF03607.17 CBY36431.1 - 6.5e-11 42.2 0.0 0.025 14.7 0.0 3.8 3 0 0 3 3 3 3 Doublecortin KHA PF11834.8 CBY36431.1 - 0.014 15.5 0.5 0.31 11.2 0.0 3.3 4 0 0 4 4 4 0 KHA, dimerisation domain of potassium ion channel OAF PF14941.6 CBY36431.1 - 0.016 14.6 0.1 0.048 13.1 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Ricin_B_lectin PF00652.22 CBY36431.1 - 0.02 15.1 0.2 0.12 12.7 0.1 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Peptidase_M1 PF01433.20 CBY36432.1 - 2.8e-61 206.9 1.5 2.8e-61 206.9 1.5 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBY36432.1 - 1.8e-55 188.7 0.4 3.4e-55 187.8 0.4 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1360 PF07098.11 CBY36432.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Peptidase_M61 PF05299.12 CBY36432.1 - 1.2 9.5 5.6 4.3 7.8 1.6 3.1 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Patched PF02460.18 CBY36433.1 - 3.4e-62 210.7 26.8 1.1e-45 156.1 2.9 2.3 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 CBY36433.1 - 3.1e-58 197.2 22.7 5.9e-50 170.1 6.8 3.2 2 1 0 2 2 2 2 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 CBY36433.1 - 4.7e-42 143.4 4.9 4.7e-42 143.4 4.9 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CBY36433.1 - 0.0005 19.1 8.4 0.0005 19.1 8.4 2.1 2 0 0 2 2 2 1 MMPL family Ribosomal_L6e PF01159.19 CBY36434.1 - 0.079 13.5 1.8 0.084 13.4 1.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e 7tm_1 PF00001.21 CBY36435.1 - 1.3e-14 54.2 19.8 2.7e-14 53.1 18.8 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY36435.1 - 0.00095 18.9 20.6 0.00095 18.9 20.6 2.6 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx PLD_C PF12357.8 CBY36435.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Phospholipase D C terminal Sulfotransfer_2 PF03567.14 CBY36436.1 - 4.5e-13 49.7 0.8 5.8e-13 49.3 0.8 1.1 1 0 0 1 1 1 1 Sulfotransferase family Inos-1-P_synth PF01658.17 CBY36436.1 - 0.028 14.6 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase DUF3268 PF11672.8 CBY36437.1 - 0.034 14.5 0.1 0.13 12.6 0.0 1.6 1 1 1 2 2 2 0 zinc-finger-containing domain FERM_C PF09380.10 CBY36438.1 - 3e-07 30.7 0.6 4.7e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FA PF08736.11 CBY36438.1 - 9.3e-06 25.6 11.7 2e-05 24.6 11.7 1.6 1 0 0 1 1 1 1 FERM adjacent (FA) Tantalus PF15386.6 CBY36440.1 - 0.0052 16.9 0.5 0.0052 16.9 0.5 2.1 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF1730 PF08331.10 CBY36440.1 - 0.09 12.7 0.1 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1730) Ribonuclease_3 PF00636.26 CBY36441.1 - 1.4e-32 112.4 0.0 1.1e-14 54.9 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CBY36441.1 - 7.6e-17 61.7 0.0 3.8e-08 33.6 0.0 4.5 4 0 0 4 4 4 3 Ribonuclease-III-like DUF3113 PF11310.8 CBY36441.1 - 0.068 13.1 0.3 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Ntox44 PF15607.6 CBY36441.1 - 0.092 13.1 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial toxin 44 Peptidase_M1 PF01433.20 CBY36442.1 - 1.6e-48 165.2 1.8 1.9e-48 164.9 0.5 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY36442.1 - 1.2e-28 100.6 0.2 2.1e-28 99.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBY36442.1 - 1.2e-12 48.0 0.2 2.5e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain RepA_N PF06970.11 CBY36442.1 - 0.099 12.6 1.3 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus PAS_9 PF13426.7 CBY36443.1 - 3.2e-09 37.0 0.1 4.4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CBY36443.1 - 8.2e-05 22.8 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CBY36443.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CBY36443.1 - 0.0042 17.3 0.1 0.0078 16.5 0.1 1.6 1 1 0 1 1 1 1 PAS fold Fucose_iso_N2 PF07882.12 CBY36443.1 - 0.076 12.6 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Ion_trans PF00520.31 CBY36444.1 - 2.6e-20 72.7 20.2 4.7e-20 71.9 20.2 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY36444.1 - 3e-09 36.7 2.1 3e-09 36.7 2.1 2.3 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY36444.1 - 8.6e-07 29.0 0.1 1.6e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2894 PF11445.8 CBY36444.1 - 0.045 14.2 0.0 0.071 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) AhpC-TSA PF00578.21 CBY36445.1 - 7e-35 119.6 0.0 1.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY36445.1 - 9.5e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY36445.1 - 2.1e-12 46.6 0.1 4.2e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF563 PF04577.14 CBY36445.1 - 0.065 13.4 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) MFS_1 PF07690.16 CBY36446.1 - 1.8e-23 83.0 36.1 1.8e-23 83.0 36.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY36446.1 - 8.7e-05 21.0 9.1 0.0002 19.8 9.1 1.7 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family T2SSM_b PF10741.9 CBY36447.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Homeodomain PF00046.29 CBY36448.1 - 7.1e-23 80.2 3.5 1.1e-22 79.6 3.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY36448.1 - 0.027 14.4 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain TraC PF07820.12 CBY36448.1 - 0.25 11.7 4.3 0.72 10.2 4.3 2.0 1 1 0 1 1 1 0 TraC-like protein PDZ PF00595.24 CBY36449.1 - 9.9e-10 38.6 0.3 0.00013 22.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY36449.1 - 7.7e-05 22.5 0.2 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY36449.1 - 0.0013 19.0 0.1 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PH_RBD PF12068.8 CBY36449.1 - 0.15 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Rab-binding domain (RBD) SSF PF00474.17 CBY36450.1 - 3e-125 418.3 16.3 4.7e-125 417.6 16.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Na_K-ATPase PF00287.18 CBY36450.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain EGF_CA PF07645.15 CBY36451.1 - 8.5e-41 137.9 111.4 1.1e-08 35.1 8.9 8.6 9 1 0 9 9 9 7 Calcium-binding EGF domain cEGF PF12662.7 CBY36451.1 - 1.3e-25 88.9 40.9 9.9e-08 31.8 0.4 8.5 7 0 0 7 7 7 5 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY36451.1 - 4.3e-18 65.2 94.2 9.6e-05 22.5 8.1 8.9 7 1 1 8 8 8 6 EGF domain FXa_inhibition PF14670.6 CBY36451.1 - 6.4e-17 61.5 92.3 3.2e-09 36.9 9.1 8.1 7 0 0 7 7 7 6 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY36451.1 - 8e-14 51.6 87.0 0.00011 22.4 7.9 8.2 9 0 0 9 9 9 6 EGF-like domain hEGF PF12661.7 CBY36451.1 - 1.1e-08 35.3 80.1 8.5e-05 23.0 2.2 9.3 9 1 0 9 9 9 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY36451.1 - 1.8e-05 24.7 19.4 0.00011 22.2 7.5 7.9 8 0 0 8 8 8 3 MSP1 EGF domain 1 Plasmod_Pvs28 PF06247.11 CBY36451.1 - 0.00036 20.8 7.1 0.00036 20.8 7.1 8.2 7 2 1 8 8 8 3 Pvs28 EGF domain EGF_2 PF07974.13 CBY36451.1 - 0.034 14.5 7.2 0.034 14.5 7.2 8.7 9 1 1 10 10 10 0 EGF-like domain Mucin PF01456.17 CBY36451.1 - 0.97 9.4 16.3 1.9 8.4 16.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DJ-1_PfpI PF01965.24 CBY36452.1 - 6.2e-08 32.6 0.2 2.4e-07 30.7 0.2 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family fn3 PF00041.21 CBY36454.1 - 2e-15 56.9 0.3 1.1e-11 44.9 0.0 3.0 3 0 0 3 3 3 2 Fibronectin type III domain fn3_2 PF16893.5 CBY36454.1 - 0.041 14.0 0.0 0.19 11.9 0.0 2.2 1 0 0 1 1 1 0 Fibronectin type III domain GDI PF00996.18 CBY36455.1 - 1.8e-36 125.6 0.3 1.1e-35 123.1 0.3 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor DnaJ PF00226.31 CBY36456.1 - 4.5e-12 45.9 0.3 1e-11 44.8 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain CbiX PF01903.17 CBY36456.1 - 0.056 13.8 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 CbiX DUF267 PF03268.14 CBY36458.1 - 0.039 12.8 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 dCMP_cyt_deam_1 PF00383.23 CBY36459.1 - 6.1e-08 32.5 0.0 7.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBY36459.1 - 5.4e-05 23.0 0.0 5.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Pkinase_Tyr PF07714.17 CBY36460.1 - 5e-85 284.9 0.0 6.5e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36460.1 - 4.8e-43 147.4 0.0 6.6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 CBY36460.1 - 9.6e-25 86.5 0.0 2.1e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Ank_2 PF12796.7 CBY36460.1 - 7.3e-21 74.6 0.7 5.3e-14 52.6 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY36460.1 - 3.3e-15 56.2 3.5 4.4e-07 30.3 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY36460.1 - 7.6e-13 47.4 0.3 0.098 13.3 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBY36460.1 - 1.2e-11 44.6 1.9 0.00011 22.4 0.0 4.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY36460.1 - 2.7e-09 37.0 2.2 0.39 11.2 0.2 4.9 4 0 0 4 4 4 4 Ankyrin repeat Kinase-like PF14531.6 CBY36460.1 - 9.3e-06 25.2 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY36460.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY36460.1 - 0.036 13.0 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain LRR_8 PF13855.6 CBY36461.1 - 4.8e-59 196.0 57.1 6.1e-16 57.9 7.2 5.2 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CBY36461.1 - 9.3e-24 83.1 41.1 1.2e-09 38.2 2.1 6.7 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY36461.1 - 2e-20 73.0 11.2 1.1e-09 38.3 1.0 2.9 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 CBY36461.1 - 5e-12 46.3 0.0 1e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain I-set PF07679.16 CBY36461.1 - 6.7e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain ig PF00047.25 CBY36461.1 - 4e-10 39.7 0.0 9.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY36461.1 - 4e-07 30.3 0.0 7.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRR_9 PF14580.6 CBY36461.1 - 3.8e-06 26.5 21.1 0.006 16.1 2.4 3.8 2 2 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CBY36461.1 - 1.6e-05 24.8 25.1 2.9 8.8 0.1 9.6 9 0 0 9 9 9 1 Leucine Rich Repeat V-set PF07686.17 CBY36461.1 - 0.00017 21.7 0.0 0.019 15.1 0.0 2.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain Nop25 PF09805.9 CBY36461.1 - 0.075 13.5 0.2 0.075 13.5 0.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) LRR_2 PF07723.13 CBY36461.1 - 0.33 11.7 6.2 0.69 10.7 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat RRM_DME PF15628.6 CBY36462.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 RRM in Demeter MCD PF05292.11 CBY36462.1 - 0.074 12.6 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain DUF3970 PF13113.6 CBY36462.1 - 0.11 12.8 0.9 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) eIF3_N PF09440.10 CBY36462.1 - 0.24 11.9 1.0 0.43 11.0 0.1 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain HAD_2 PF13419.6 CBY36463.1 - 9.3e-18 64.9 0.0 1e-17 64.8 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY36463.1 - 1.9e-07 31.6 0.0 2.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY36463.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like CoA_trans PF01144.23 CBY36464.1 - 4.7e-118 392.3 5.4 7.3e-75 251.1 0.4 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CBY36464.1 - 0.00074 18.0 0.0 0.0011 17.4 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 CBY36464.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain TcpS PF17456.2 CBY36465.1 - 0.018 15.1 4.0 0.026 14.6 3.7 1.3 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S NPV_P10 PF05531.12 CBY36465.1 - 0.17 12.3 6.1 4.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMA7 PF09072.10 CBY36466.1 - 4.5e-24 85.0 21.0 4.9e-24 84.9 21.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ion_trans_2 PF07885.16 CBY36473.1 - 1e-05 25.4 1.8 1.8e-05 24.6 1.8 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY36473.1 - 0.038 13.2 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein Nnf1 PF03980.14 CBY36473.1 - 1.3 9.4 8.4 0.45 10.9 4.0 2.4 2 1 0 2 2 2 0 Nnf1 Peptidase_A3 PF02160.15 CBY36473.1 - 6.2 6.2 7.6 1.1 8.7 0.6 2.3 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) ANAPC1 PF12859.7 CBY36473.1 - 6.2 7.4 7.8 2.8 8.5 0.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Ribosomal_S3_C PF00189.20 CBY36474.1 - 2.1e-24 85.8 1.6 1.9e-23 82.8 1.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBY36474.1 - 5e-11 42.3 0.4 9.6e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 CBY36474.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus zf-C3HC4 PF00097.25 CBY36475.1 - 4.5e-09 36.0 8.5 4.5e-09 36.0 8.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY36475.1 - 4.8e-09 36.1 6.8 1.1e-08 34.9 6.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY36475.1 - 3.8e-08 33.5 9.2 7.6e-08 32.6 8.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY36475.1 - 8.8e-08 31.9 6.0 1.8e-07 30.9 6.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY36475.1 - 6.7e-07 29.1 9.3 6.7e-07 29.1 9.3 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY36475.1 - 5.1e-06 26.3 7.8 0.00021 21.1 8.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY36475.1 - 8.8e-06 25.8 7.8 1.9e-05 24.7 7.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 CBY36475.1 - 0.00012 22.0 1.7 0.00023 21.1 1.7 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 CBY36475.1 - 0.00028 20.8 8.8 0.0011 18.9 8.8 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY36475.1 - 0.0017 18.1 4.1 0.0066 16.2 4.1 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4428 PF14471.6 CBY36475.1 - 0.024 14.5 2.7 3.4 7.7 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Zn_Tnp_IS91 PF14319.6 CBY36475.1 - 0.06 13.4 2.3 0.06 13.4 2.3 1.5 2 0 0 2 2 2 0 Transposase zinc-binding domain DZR PF12773.7 CBY36475.1 - 0.061 13.4 3.1 0.22 11.6 3.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon Fer2 PF00111.27 CBY36475.1 - 0.16 12.0 1.6 1.8 8.5 1.6 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_11 PF17123.5 CBY36475.1 - 0.18 11.6 7.5 0.68 9.7 7.5 2.0 1 1 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CBY36475.1 - 0.38 11.1 10.7 1.9 8.9 9.3 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-piccolo PF05715.13 CBY36475.1 - 0.9 9.7 6.3 6.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger PsbM PF05151.12 CBY36475.1 - 6.1 6.7 12.6 1.2 9.0 8.8 1.8 1 1 1 2 2 2 0 Photosystem II reaction centre M protein (PsbM) zf-C3HC4 PF00097.25 CBY36476.1 - 7.2e-08 32.2 8.1 3.1e-07 30.2 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY36476.1 - 4e-07 29.9 6.9 1.2e-05 25.3 2.7 2.3 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY36476.1 - 5.7e-07 29.3 3.0 5.7e-07 29.3 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY36476.1 - 8.2e-07 29.3 7.3 1.3e-06 28.7 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY36476.1 - 8.7e-06 25.5 8.0 3.7e-05 23.5 8.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY36476.1 - 0.00012 22.2 8.4 0.0012 19.0 9.0 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBY36476.1 - 0.0022 17.9 9.5 0.06 13.3 10.6 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-4CXXC_R1 PF10497.9 CBY36476.1 - 0.046 13.9 4.6 0.091 13.0 4.6 1.4 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 CBY36476.1 - 0.074 12.9 7.6 1.1 9.1 7.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 NUC153 PF08159.12 CBY36476.1 - 0.15 11.9 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NUC153 domain zf-RING_4 PF14570.6 CBY36476.1 - 0.15 11.8 6.7 0.4 10.5 3.8 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 CBY36476.1 - 0.29 11.4 3.1 6.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 CBY36476.1 - 0.55 10.3 4.0 2.1 8.5 4.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBY36476.1 - 0.98 9.8 11.0 9.9 6.5 11.0 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain Carb_anhydrase PF00194.21 CBY36477.1 - 8.1e-35 120.6 5.6 1.2e-34 120.0 5.6 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Trypan_PARP PF05887.11 CBY36477.1 - 1.3 9.0 16.3 2.6 8.0 16.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PMP22_Claudin PF00822.20 CBY36478.1 - 1.8e-09 37.7 5.2 5.8e-09 36.0 4.1 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY36478.1 - 1.5e-07 31.4 3.5 0.00028 20.7 6.0 3.0 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 CBY36478.1 - 7.5e-05 23.0 1.6 0.00018 21.8 1.6 1.6 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein MscS_TM PF12794.7 CBY36478.1 - 0.094 11.6 0.5 0.15 10.9 0.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1461 PF07314.11 CBY36478.1 - 0.1 12.5 0.5 0.19 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Trp_oprn_chp PF09534.10 CBY36478.1 - 0.1 12.4 0.0 0.7 9.7 0.0 2.3 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RseC_MucC PF04246.12 CBY36478.1 - 0.14 12.1 0.7 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EF-hand_6 PF13405.6 CBY36480.1 - 5.6e-05 22.7 0.2 0.029 14.3 0.0 3.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBY36480.1 - 0.00023 20.5 3.8 0.027 14.0 0.0 3.9 4 1 1 5 5 5 1 EF hand EF-hand_8 PF13833.6 CBY36480.1 - 0.00074 19.3 4.8 0.003 17.4 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CBY36480.1 - 0.00082 19.8 0.2 0.002 18.6 0.1 1.7 2 1 0 2 2 2 1 EF-hand domain pair LRR_4 PF12799.7 CBY36483.1 - 4.2e-16 58.8 20.3 0.0001 22.6 0.1 4.3 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY36483.1 - 8.5e-16 57.5 24.0 1.5e-06 27.9 2.9 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRRNT PF01462.18 CBY36483.1 - 4.4e-09 35.8 1.2 1.3e-08 34.2 1.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 CBY36483.1 - 4.4e-06 26.3 5.0 0.0001 21.8 0.8 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_2 PF07723.13 CBY36483.1 - 5.3e-05 23.7 5.0 0.3 11.8 0.0 5.5 4 2 2 6 6 6 1 Leucine Rich Repeat LRR_1 PF00560.33 CBY36483.1 - 0.00016 21.8 18.2 2.1 9.2 0.1 6.2 6 0 0 6 6 6 3 Leucine Rich Repeat FNIP PF05725.12 CBY36483.1 - 0.00027 21.0 4.5 0.0023 18.0 0.2 3.3 3 1 0 3 3 3 1 FNIP Repeat LRR_6 PF13516.6 CBY36483.1 - 0.00064 19.6 16.3 0.11 12.6 1.0 5.3 6 0 0 6 6 6 3 Leucine Rich repeat Zona_pellucida PF00100.23 CBY36484.1 - 4.7e-21 75.7 1.6 7.2e-21 75.1 1.4 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain DUF2970 PF11174.8 CBY36484.1 - 0.027 14.3 2.7 0.046 13.6 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Saf_2TM PF18303.1 CBY36484.1 - 0.099 12.2 0.6 0.16 11.5 0.6 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Ig_3 PF13927.6 CBY36485.1 - 4.5e-27 94.5 0.4 8.5e-11 42.3 0.0 4.9 4 1 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY36485.1 - 1.7e-25 89.2 0.0 1.8e-09 37.8 0.0 5.0 5 0 0 5 5 5 3 Immunoglobulin domain I-set PF07679.16 CBY36485.1 - 5e-20 71.4 3.5 3.4e-08 33.4 0.0 5.4 5 1 0 5 5 5 3 Immunoglobulin I-set domain ig PF00047.25 CBY36485.1 - 7.8e-19 67.7 2.0 6.6e-06 26.2 0.0 5.2 5 0 0 5 5 5 3 Immunoglobulin domain V-set PF07686.17 CBY36485.1 - 7.7e-16 58.2 3.6 0.026 14.7 0.0 6.4 5 1 1 6 6 6 5 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY36485.1 - 1.1e-13 50.5 0.1 0.00051 19.5 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Ig_5 PF16681.5 CBY36485.1 - 1.3e-08 35.1 0.1 0.1 13.0 0.0 4.3 4 0 0 4 4 4 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY36485.1 - 1.2e-06 28.7 0.3 4 7.8 0.0 4.8 5 0 0 5 5 5 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CBY36485.1 - 4.6e-06 26.6 1.0 2.8 8.1 0.0 4.2 5 0 0 5 5 5 3 Izumo-like Immunoglobulin domain fn3 PF00041.21 CBY36485.1 - 6.6e-05 23.2 0.0 0.0002 21.6 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY36485.1 - 0.11 13.1 0.1 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Cadherin_C_2 PF16492.5 CBY36486.1 - 0.033 14.9 0.0 0.18 12.5 0.0 2.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Tad PF13400.6 CBY36486.1 - 0.064 13.6 0.4 0.1 12.9 0.4 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like EF-hand_7 PF13499.6 CBY36487.1 - 7.4e-17 61.6 2.7 1.5e-08 35.0 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY36487.1 - 2.5e-11 42.3 1.5 0.002 17.6 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY36487.1 - 4.1e-11 41.9 1.5 0.0051 16.6 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBY36487.1 - 1.3e-08 34.5 2.7 3.9e-07 29.8 0.0 3.5 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY36487.1 - 6.9e-06 25.3 1.7 0.099 12.2 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_11 PF08976.11 CBY36487.1 - 0.011 16.6 0.2 0.13 13.2 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain DUF3316 PF11777.8 CBY36487.1 - 0.13 12.4 0.1 4.4 7.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) Peptidase_M15_4 PF13539.6 CBY36488.1 - 7.5e-07 29.6 0.2 2.1e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_3 PF08291.11 CBY36488.1 - 0.045 13.8 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 Orthopox_C10L PF07020.11 CBY36488.1 - 2.6 8.8 15.8 1.6 9.5 13.4 1.9 1 1 1 2 2 2 0 Orthopoxvirus C10L protein Zona_pellucida PF00100.23 CBY36489.1 - 4.6e-33 115.1 2.2 7e-33 114.5 2.2 1.3 1 0 0 1 1 1 1 Zona pellucida-like domain DPBB_1 PF03330.18 CBY36490.1 - 0.00072 19.8 0.5 0.0034 17.6 0.3 2.0 2 0 0 2 2 2 1 Lytic transglycolase DUF3747 PF12565.8 CBY36490.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) COesterase PF00135.28 CBY36491.1 - 2.5e-56 191.6 0.0 3.2e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY36491.1 - 0.00011 22.1 0.2 0.00062 19.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pterin_4a PF01329.19 CBY36492.1 - 9.9e-09 35.3 0.1 1.3e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Bax1-I PF01027.20 CBY36493.1 - 1.8e-06 27.9 34.6 2.1e-05 24.5 34.6 1.9 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 HSP70 PF00012.20 CBY36494.1 - 5.3e-126 421.2 9.3 6.5e-126 420.9 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY36494.1 - 5.5e-11 41.9 2.8 1.9e-08 33.5 1.6 2.9 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CBY36494.1 - 4.6e-05 23.8 1.0 0.2 12.1 0.2 3.3 2 1 0 2 2 2 2 Cell division protein FtsA StbA PF06406.11 CBY36494.1 - 0.00058 19.2 0.7 0.03 13.6 0.0 2.6 1 1 1 2 2 2 1 StbA protein DDR PF08841.10 CBY36494.1 - 0.00087 18.4 1.3 0.031 13.3 0.0 2.8 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain AnmK PF03702.14 CBY36494.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase BcrAD_BadFG PF01869.20 CBY36494.1 - 0.038 13.5 0.0 0.54 9.7 0.0 2.4 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family SpoIIAA-like PF11964.8 CBY36494.1 - 0.055 14.5 0.0 0.24 12.4 0.0 2.1 1 0 0 1 1 1 0 SpoIIAA-like TPP_enzyme_N PF02776.18 CBY36494.1 - 0.15 11.6 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Hydantoinase_A PF01968.18 CBY36494.1 - 0.18 11.1 0.8 2.8 7.1 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Mcl1_mid PF12341.8 CBY36495.1 - 3.3e-69 233.5 0.1 4.8e-69 233.0 0.1 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region Kelch_5 PF13854.6 CBY36496.1 - 1.4e-21 76.0 5.4 7.9e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBY36496.1 - 3.4e-18 65.2 1.7 2.4e-08 34.0 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CBY36496.1 - 2.6e-16 58.9 3.4 2.6e-09 36.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CBY36496.1 - 4.5e-15 55.4 3.3 1.5e-07 31.3 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY36496.1 - 2.1e-13 50.2 0.0 0.00019 21.6 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY36496.1 - 7.4e-11 41.6 8.5 8.3e-05 22.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CBY36497.1 - 7.6e-05 22.2 0.7 0.00012 21.5 0.2 1.7 2 1 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CBY36497.1 - 0.002 18.1 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CBY36497.1 - 0.0093 16.2 0.1 0.53 10.6 0.1 2.6 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY36497.1 - 0.013 15.5 0.2 0.022 14.7 0.0 1.5 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.6 CBY36497.1 - 0.2 12.0 1.3 2.2 8.7 1.3 2.2 1 1 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 CBY36497.1 - 0.52 10.3 2.5 0.35 10.9 0.5 2.0 2 1 0 2 2 2 0 Galactose oxidase, central domain AAA PF00004.29 CBY36498.1 - 3.6e-19 69.5 0.0 6.8e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBY36498.1 - 8.2e-19 67.8 1.7 1.3e-18 67.2 0.2 2.1 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY36498.1 - 3.3e-14 53.0 0.0 4.1e-10 39.7 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CBY36498.1 - 1e-09 38.6 0.0 2.2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBY36498.1 - 1.3e-06 28.2 0.1 7.4e-06 25.8 0.1 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CBY36498.1 - 1.7e-05 24.9 0.1 0.008 16.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_assoc_2 PF16193.5 CBY36498.1 - 2e-05 24.9 0.1 5e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 CBY36498.1 - 2.7e-05 24.2 0.0 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBY36498.1 - 3.2e-05 23.9 0.2 0.00027 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY36498.1 - 4.4e-05 23.9 0.0 0.0068 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY36498.1 - 4.6e-05 23.7 0.1 0.0042 17.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY36498.1 - 8.2e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBY36498.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CBY36498.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY36498.1 - 0.00047 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CBY36498.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.13 CBY36498.1 - 0.0019 17.5 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 CBY36498.1 - 0.0023 18.3 0.2 0.011 16.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY36498.1 - 0.004 16.9 0.2 0.021 14.6 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBY36498.1 - 0.005 16.6 0.1 0.016 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY36498.1 - 0.0074 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CBY36498.1 - 0.0098 16.4 0.3 0.047 14.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 CBY36498.1 - 0.011 15.2 0.1 0.058 12.8 0.0 1.9 1 1 1 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 CBY36498.1 - 0.011 15.1 0.1 0.63 9.4 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CBY36498.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CBY36498.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CBY36498.1 - 0.035 13.9 0.1 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBY36498.1 - 0.036 13.8 0.0 5.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain TniB PF05621.11 CBY36498.1 - 0.046 13.1 0.1 2.6 7.4 0.0 2.3 1 1 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 CBY36498.1 - 0.054 13.9 0.3 0.34 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase UQ_con PF00179.26 CBY36499.1 - 1.4e-21 76.6 0.0 2.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FKBP_N PF01346.18 CBY36499.1 - 0.18 12.8 3.1 0.5 11.4 3.1 1.8 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FlxA PF14282.6 CBY36499.1 - 1.1 9.3 6.0 4.8 7.2 2.7 2.4 2 0 0 2 2 2 0 FlxA-like protein Folate_rec PF03024.14 CBY36500.1 - 9.2e-14 51.7 12.7 1.5e-13 51.0 12.7 1.3 1 0 0 1 1 1 1 Folate receptor family DUF3149 PF11346.8 CBY36500.1 - 0.024 14.2 0.5 0.048 13.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF1947 PF09183.10 CBY36500.1 - 0.036 14.3 1.1 0.83 10.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) PetM PF08041.11 CBY36501.1 - 1.2 8.8 4.1 4.2 7.1 0.2 2.2 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 GST_C_3 PF14497.6 CBY36503.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PRKCSH-like PF12999.7 CBY36503.1 - 0.24 11.2 2.8 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like Myotub-related PF06602.14 CBY36504.1 - 2.9e-77 260.0 0.0 4.4e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FDX-ACB PF03147.14 CBY36505.1 - 0.035 14.5 0.1 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain WD40 PF00400.32 CBY36506.1 - 3.7e-08 33.9 0.1 0.015 16.1 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36506.1 - 0.00018 21.8 0.0 0.071 13.4 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_2 PF07646.15 CBY36506.1 - 0.032 14.2 0.3 18 5.5 0.0 3.7 4 0 0 4 4 4 0 Kelch motif CPSF_A PF03178.15 CBY36506.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region Securin PF04856.13 CBY36507.1 - 0.035 14.1 1.8 0.063 13.2 1.8 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Retrotrans_gag PF03732.17 CBY36507.1 - 0.053 13.8 1.4 0.071 13.4 0.2 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Kelch_5 PF13854.6 CBY36508.1 - 3e-07 30.3 0.9 0.0013 18.6 0.3 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CBY36508.1 - 0.0045 17.2 0.3 0.41 11.0 0.2 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY36508.1 - 0.026 14.5 1.1 0.16 12.0 0.5 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 CBY36508.1 - 0.12 12.0 4.3 2.7 7.7 2.3 3.1 2 1 1 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY36508.1 - 0.12 12.3 3.7 0.67 10.0 2.0 2.4 2 1 0 2 2 2 0 Galactose oxidase, central domain Pan3_PK PF18101.1 CBY36510.1 - 2e-41 141.2 0.0 3.2e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CBY36510.1 - 2.4e-09 36.9 0.0 6.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36510.1 - 0.00096 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_tail_1 PF01576.19 CBY36511.1 - 2.1e-88 297.4 177.6 2.6e-88 297.1 177.6 1.0 1 0 0 1 1 1 1 Myosin tail Coronavirus_5 PF05528.11 CBY36512.1 - 0.038 14.0 0.3 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Coronavirus gene 5 protein DUF35_N PF12172.8 CBY36512.1 - 0.8 9.6 5.6 3.1 7.8 4.8 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Methyltransf_22 PF13383.6 CBY36513.1 - 2.1e-15 57.0 0.1 3.4e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PAS_10 PF13596.6 CBY36513.1 - 0.14 12.7 0.1 1.2 9.8 0.1 2.2 2 0 0 2 2 2 0 PAS domain Neur_chan_memb PF02932.16 CBY36515.1 - 8.4e-26 91.5 0.5 8.9e-26 91.4 0.5 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CpxA_peri PF16527.5 CBY36517.1 - 0.15 12.5 1.2 29 5.1 0.8 2.5 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain TUSC2 PF15000.6 CBY36517.1 - 0.16 12.2 5.5 0.69 10.2 0.8 2.7 2 0 0 2 2 2 0 Tumour suppressor candidate 2 Auxin_repressed PF05564.12 CBY36520.1 - 0.46 11.2 0.1 0.46 11.2 0.1 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein BORCS8 PF10167.9 CBY36522.1 - 1e-16 60.8 0.1 1.2e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 M-factor PF03855.13 CBY36522.1 - 0.091 12.9 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 M-factor NACHT PF05729.12 CBY36522.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 NACHT domain DUF4750 PF15938.5 CBY36525.1 - 7.4e-08 31.9 0.7 9.1e-08 31.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) Sugar_tr PF00083.24 CBY36526.1 - 1.5e-11 43.9 7.9 1.1e-10 41.0 7.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY36526.1 - 5.9e-11 41.9 14.5 5.7e-09 35.4 7.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Zona_pellucida PF00100.23 CBY36527.1 - 9.3e-43 146.9 5.9 1.1e-42 146.6 5.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF4389 PF14333.6 CBY36527.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DAG1 PF05454.11 CBY36527.1 - 0.29 10.5 1.6 2.8 7.2 0.3 2.3 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PLAC8 PF04749.17 CBY36528.1 - 1.2e-09 39.1 21.1 1.5e-09 38.7 21.1 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.17 CBY36529.1 - 4.1e-66 222.9 0.0 7.3e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36529.1 - 5.4e-28 98.1 0.0 9.4e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fz PF01392.22 CBY36529.1 - 1.6e-08 35.1 5.7 4.9e-08 33.6 5.7 1.8 1 0 0 1 1 1 1 Fz domain Kringle PF00051.18 CBY36529.1 - 1e-07 32.1 3.6 1.5e-07 31.6 1.6 2.5 2 0 0 2 2 2 1 Kringle domain Haspin_kinase PF12330.8 CBY36529.1 - 0.0078 15.2 0.0 0.021 13.8 0.0 1.7 1 0 0 1 1 1 1 Haspin like kinase domain I_LWEQ PF01608.17 CBY36530.1 - 3.1e-59 199.6 141.1 2.9e-39 134.7 9.8 17.7 8 4 8 18 18 18 11 I/LWEQ domain FERM_M PF00373.18 CBY36530.1 - 1.4e-15 57.7 2.8 3.8e-15 56.3 0.2 2.9 2 0 0 2 2 2 1 FERM central domain Talin_middle PF09141.10 CBY36530.1 - 8.9e-10 38.8 1.4 8.9e-10 38.8 1.4 15.2 8 6 7 15 15 15 3 Talin, middle domain FERM_N PF09379.10 CBY36530.1 - 4.6e-06 26.5 1.0 0.00013 21.9 0.3 2.9 3 0 0 3 3 3 1 FERM N-terminal domain VBS PF08913.10 CBY36530.1 - 0.0031 17.9 3.6 0.0031 17.9 3.6 9.3 9 1 1 10 10 10 2 Vinculin Binding Site DUF1296 PF06972.11 CBY36530.1 - 0.018 15.1 1.4 5.1 7.3 0.0 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Snapin_Pallidin PF14712.6 CBY36530.1 - 0.92 10.0 20.1 0.051 14.0 1.9 6.4 5 0 0 5 5 5 0 Snapin/Pallidin F_actin_bind PF08919.10 CBY36530.1 - 1.3 9.1 24.0 0.76 9.9 0.6 8.0 6 1 0 7 7 7 0 F-actin binding RtcB PF01139.17 CBY36531.1 - 9.2e-24 84.4 0.1 1.1e-23 84.1 0.1 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Pyridox_oxase_2 PF12766.7 CBY36532.1 - 0.081 13.5 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1463 PF07316.11 CBY36533.1 - 0.05 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) DUF3844 PF12955.7 CBY36534.1 - 2.3 8.4 7.2 1.4 9.1 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Es2 PF09751.9 CBY36535.1 - 4.9e-55 188.0 13.3 4.9e-55 188.0 13.3 2.0 1 1 1 2 2 2 1 Nuclear protein Es2 PQ-loop PF04193.14 CBY36535.1 - 8.1e-15 54.3 6.2 3.1e-09 36.5 1.9 2.8 2 0 0 2 2 2 2 PQ loop repeat ETC_C1_NDUFA4 PF04800.12 CBY36536.1 - 2.5e-30 104.6 2.4 3.7e-30 104.0 2.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ribosomal_60s PF00428.19 CBY36537.1 - 5.6e-22 78.1 2.5 6.5e-22 77.9 2.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPR_1 PF00515.28 CBY36538.1 - 2.5e-17 61.9 10.0 0.00034 20.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36538.1 - 1.3e-15 56.1 16.2 0.0086 16.1 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CBY36538.1 - 2e-10 41.0 4.5 0.04 14.4 0.0 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36538.1 - 1.2e-08 35.1 6.7 2.5 9.2 0.1 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36538.1 - 2.6e-08 34.1 7.7 0.17 12.2 0.5 5.4 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36538.1 - 5.1e-08 33.4 9.3 3.9e-06 27.4 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36538.1 - 9.5e-07 28.4 6.0 0.01 15.5 0.0 5.4 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 CBY36538.1 - 5.6e-05 22.9 8.1 0.54 10.4 0.0 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY36538.1 - 0.00013 22.0 7.4 0.17 12.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY36538.1 - 0.00022 20.5 0.0 0.4 9.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36538.1 - 0.0025 17.9 12.8 4.1 7.8 0.0 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36538.1 - 0.004 17.7 7.3 4.8 8.0 0.0 5.5 7 0 0 7 7 4 1 Tetratricopeptide repeat MIT PF04212.18 CBY36538.1 - 0.03 14.4 8.2 2.2 8.4 0.4 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBY36538.1 - 0.054 13.4 6.0 32 4.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36538.1 - 0.078 13.4 0.1 29 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY36538.1 - 0.15 11.5 3.1 14 5.3 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR SnAPC_2_like PF11035.8 CBY36539.1 - 1.5e-06 28.6 0.3 1.5e-06 28.6 0.3 3.7 2 2 0 3 3 3 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF1805 PF08827.11 CBY36539.1 - 0.03 14.7 0.7 23 5.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) Radical_SAM_N PF08497.10 CBY36539.1 - 0.44 9.7 4.1 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Radical SAM N-terminal Zip PF02535.22 CBY36541.1 - 1.1e-11 44.6 8.6 6.7e-11 42.0 8.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter HAS-barrel PF09378.10 CBY36541.1 - 0.051 13.7 0.3 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 HAS barrel domain Hid1 PF12722.7 CBY36541.1 - 2.4 6.2 4.4 3 5.9 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MBOAT PF03062.19 CBY36542.1 - 2.2e-11 43.7 13.9 7.2e-11 42.0 13.7 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF2070 PF09843.9 CBY36542.1 - 1.8 6.8 8.4 0.049 11.9 2.5 1.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) TMEM208_SND2 PF05620.11 CBY36543.1 - 0.011 15.5 1.8 0.028 14.2 0.0 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF3624 PF12292.8 CBY36543.1 - 0.027 14.9 0.6 0.06 13.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) TIL PF01826.17 CBY36544.1 - 6.2e-26 90.4 155.3 9.3e-10 38.6 19.5 8.4 6 2 2 8 8 8 5 Trypsin Inhibitor like cysteine rich domain cNMP_binding PF00027.29 CBY36546.1 - 0.00012 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBY36546.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Guanylate_cyc PF00211.20 CBY36549.1 - 3.2e-60 202.9 0.0 9.2e-60 201.4 0.0 1.8 3 0 0 3 3 3 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY36549.1 - 1.5e-25 89.9 0.0 3.2e-25 88.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36549.1 - 6.3e-19 68.4 0.0 2.1e-18 66.6 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain HNOBA PF07701.14 CBY36549.1 - 0.00019 20.9 2.2 0.0003 20.3 2.2 1.3 1 0 0 1 1 1 1 Heme NO binding associated LRR_4 PF12799.7 CBY36550.1 - 4.3e-40 135.0 59.9 2.7e-08 34.0 1.6 11.2 6 3 5 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY36550.1 - 7.6e-31 105.7 57.0 4.1e-09 36.1 6.0 8.8 7 2 2 9 9 9 7 Leucine rich repeat LRR_9 PF14580.6 CBY36550.1 - 9.7e-20 70.8 27.1 8.9e-12 44.8 2.6 5.4 4 2 1 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 CBY36550.1 - 1.6e-13 49.5 43.6 1.4 9.1 0.1 14.2 16 0 0 16 16 16 8 Leucine Rich repeat LRR_1 PF00560.33 CBY36550.1 - 0.17 12.5 57.8 1.8 9.4 0.3 12.4 10 6 1 11 11 11 0 Leucine Rich Repeat LRR_2 PF07723.13 CBY36550.1 - 8.9 7.2 18.1 43 5.0 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 CBY36551.1 - 2.1e-14 53.4 9.6 9.5e-05 22.7 0.1 5.3 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY36551.1 - 3.3e-10 39.7 3.5 2.2e-09 37.1 1.3 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBY36551.1 - 7.1e-09 35.3 8.8 0.00068 19.4 0.4 4.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 CBY36551.1 - 0.008 16.6 0.4 45 5.2 0.0 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat Carbpep_Y_N PF05388.11 CBY36551.1 - 0.11 13.0 2.5 0.14 12.7 0.4 2.3 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide LRR_6 PF13516.6 CBY36551.1 - 0.13 12.4 3.6 5.7 7.3 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Ig_3 PF13927.6 CBY36552.1 - 0.0028 18.2 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY36552.1 - 0.0041 17.4 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY36552.1 - 0.016 15.4 0.1 0.058 13.6 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin V-set domain Pkinase_Tyr PF07714.17 CBY36553.1 - 1.1e-76 257.5 0.0 1.9e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36553.1 - 1.8e-35 122.6 0.0 2.9e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SieB PF14163.6 CBY36553.1 - 0.00084 18.9 0.1 0.0027 17.2 0.1 1.8 1 0 0 1 1 1 1 Super-infection exclusion protein B Ribosomal_S20p PF01649.18 CBY36553.1 - 0.0077 16.8 0.1 24 5.6 0.0 3.7 4 0 0 4 4 4 1 Ribosomal protein S20 Pkinase_fungal PF17667.1 CBY36553.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Sugar_tr PF00083.24 CBY36554.1 - 3.1e-98 329.6 18.8 4.2e-71 240.1 9.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY36554.1 - 6.1e-32 110.9 27.2 2.4e-28 99.1 15.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CBY36554.1 - 0.0021 16.5 4.0 0.0028 16.2 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Defensin_beta_2 PF13841.6 CBY36554.1 - 0.088 13.3 0.5 0.19 12.3 0.5 1.6 1 0 0 1 1 1 0 Beta defensin MFS_2 PF13347.6 CBY36554.1 - 3.8 6.0 22.4 0.036 12.6 2.3 3.7 2 1 1 4 4 4 0 MFS/sugar transport protein Aldedh PF00171.22 CBY36555.1 - 1.3e-128 429.4 0.1 1.6e-128 429.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SIKE PF05769.11 CBY36556.1 - 4.4e-17 62.6 8.1 4.4e-17 62.6 8.1 1.9 2 0 0 2 2 2 1 SIKE family LIAS_N PF16881.5 CBY36556.1 - 0.061 13.7 3.2 0.1 13.0 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family DUF45 PF01863.17 CBY36556.1 - 0.96 9.4 4.2 0.7 9.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF4661 PF15576.6 CBY36556.1 - 1.4 8.8 5.1 1 9.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) YabA PF06156.13 CBY36556.1 - 5.8 7.6 12.1 9.6 6.9 0.3 3.5 2 2 0 3 3 3 0 Initiation control protein YabA DEAD_assoc PF08494.11 CBY36557.1 - 0.029 14.2 0.3 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 DEAD/H associated ADIP PF11559.8 CBY36557.1 - 0.083 13.0 23.2 0.23 11.6 11.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 CBY36557.1 - 0.088 12.7 2.8 2.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vps54_N PF10475.9 CBY36557.1 - 0.12 11.7 12.8 0.061 12.6 6.9 2.2 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Exonuc_VII_L PF02601.15 CBY36557.1 - 0.26 10.8 8.7 0.29 10.7 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO-like PF16789.5 CBY36557.1 - 0.62 10.1 22.5 0.069 13.2 10.7 2.2 1 1 1 2 2 2 0 YscO-like protein DUF724 PF05266.14 CBY36557.1 - 0.89 9.3 21.8 2.1 8.1 11.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 CBY36557.1 - 1.1 8.7 19.5 1.4 8.3 19.0 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 CBY36557.1 - 1.5 8.8 28.9 3.2 7.8 28.9 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Paralemmin PF03285.15 CBY36557.1 - 1.9 8.0 21.6 2.6 7.5 12.3 2.1 1 1 1 2 2 2 0 Paralemmin Fez1 PF06818.15 CBY36557.1 - 2 8.8 20.7 5.7 7.3 4.1 2.2 1 1 1 2 2 2 0 Fez1 TPR_MLP1_2 PF07926.12 CBY36557.1 - 2.5 8.2 24.6 1.4 9.0 18.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 CBY36557.1 - 2.7 8.5 15.9 0.48 10.9 2.2 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF5339 PF17274.2 CBY36557.1 - 3.6 8.5 14.6 0.85 10.5 4.7 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5339) NPV_P10 PF05531.12 CBY36557.1 - 5.7 7.5 9.0 3 8.4 3.5 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 CBY36557.1 - 6.1 7.5 8.0 4.8 7.9 3.4 2.9 1 1 1 2 2 2 0 SlyX PRKG1_interact PF15898.5 CBY36557.1 - 9.1 7.2 25.3 2.1 9.3 15.2 2.9 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 CBY36557.1 - 9.9 5.4 15.9 0.59 9.5 9.3 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M AKAP28 PF14469.6 CBY36558.1 - 1.3e-47 160.5 0.2 1.5e-47 160.3 0.2 1.0 1 0 0 1 1 1 1 28 kDa A-kinase anchor Motile_Sperm PF00635.26 CBY36559.1 - 0.037 13.9 0.1 0.57 10.1 0.0 2.7 3 0 0 3 3 3 0 MSP (Major sperm protein) domain ASH PF15780.5 CBY36560.1 - 7.3e-42 141.5 24.2 0.0039 17.4 0.0 19.9 20 2 1 21 21 21 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY36560.1 - 7.3e-20 70.8 6.6 0.01 15.6 0.0 10.9 11 0 0 11 11 11 5 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CBY36560.1 - 2e-15 56.8 11.9 0.66 10.3 0.0 12.0 12 0 0 12 12 12 4 Transmembrane protein 131-like MYCBPAP PF14646.6 CBY36560.1 - 1.8e-12 47.0 16.4 0.22 10.4 0.0 9.5 11 0 0 11 11 11 5 MYCBP-associated protein family DUF1573 PF07610.11 CBY36560.1 - 4.3e-12 45.9 8.7 0.42 10.7 0.0 13.0 17 0 0 17 17 17 2 Protein of unknown function (DUF1573) Hydin_ADK PF17213.3 CBY36560.1 - 1.4e-08 35.3 25.3 1.7e-07 31.7 0.0 4.5 4 1 1 5 5 5 2 Hydin Adenylate kinase-like domain PapD-like PF14874.6 CBY36560.1 - 7.8e-05 22.8 0.0 1.3 9.2 0.0 5.0 4 1 0 4 4 4 1 Flagellar-associated PapD-like ADK PF00406.22 CBY36560.1 - 0.00051 20.2 1.0 0.52 10.4 1.3 3.4 2 1 0 2 2 2 1 Adenylate kinase SKI PF01202.22 CBY36560.1 - 0.0096 16.0 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 CBY36560.1 - 0.14 12.7 0.7 0.85 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBY36560.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.6 3 1 1 4 4 3 0 AAA domain MID_MedPIWI PF18296.1 CBY36560.1 - 1.8 8.3 12.1 0.48 10.2 1.7 2.5 2 0 0 2 2 2 0 MID domain of medPIWI Collagen PF01391.18 CBY36561.1 - 3.5e-122 398.2 491.9 6.6e-10 38.6 29.6 17.3 3 3 13 16 16 16 15 Collagen triple helix repeat (20 copies) C4 PF01413.19 CBY36561.1 - 1e-31 109.6 0.6 2e-20 73.2 0.1 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen Peptidase_M20 PF01546.28 CBY36562.1 - 4.1e-33 114.8 0.0 6.5e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY36562.1 - 3.4e-14 52.7 0.0 5.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 CBY36563.1 - 3.4e-33 115.1 0.0 5.4e-33 114.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY36563.1 - 3.7e-10 39.7 0.0 6.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain MutS_IV PF05190.18 CBY36564.1 - 0.0078 16.5 0.7 0.023 15.0 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV Csm4_C PF17953.1 CBY36565.1 - 0.0027 17.5 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 CRISPR Csm4 C-terminal domain Ricin_B_lectin PF00652.22 CBY36566.1 - 0.11 12.7 0.0 0.43 10.8 0.0 1.9 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain TOC159_MAD PF11886.8 CBY36567.1 - 0.028 13.3 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain LPP PF04728.13 CBY36567.1 - 0.047 14.1 9.5 1.6 9.2 1.1 3.0 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Zona_pellucida PF00100.23 CBY36568.1 - 2.2e-11 44.1 0.5 2.7e-11 43.8 0.5 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain zf-TAZ PF02135.16 CBY36569.1 - 2.7e-07 30.9 17.3 2.7e-07 30.9 17.3 2.0 2 0 0 2 2 2 1 TAZ zinc finger HisK_N PF09385.10 CBY36569.1 - 0.055 13.4 1.1 0.1 12.5 1.1 1.4 1 0 0 1 1 1 0 Histidine kinase N terminal BAT2_N PF07001.11 CBY36570.1 - 5.5 7.4 6.6 0.39 11.2 1.4 1.6 2 0 0 2 2 2 0 BAT2 N-terminus Cse1 PF08506.10 CBY36571.1 - 1.1e-128 429.2 0.8 2.6e-128 428.0 0.2 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CBY36571.1 - 5.5e-95 318.5 1.1 1e-94 317.6 1.1 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CBY36571.1 - 3.2e-11 43.0 1.2 3.4e-10 39.7 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBY36571.1 - 1.4e-05 25.2 2.7 1.8 8.6 0.1 5.3 5 1 0 5 5 5 2 Exportin 1-like protein Cnd3 PF12719.7 CBY36571.1 - 0.0031 16.8 0.4 0.013 14.8 0.4 2.1 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CBY36571.1 - 0.049 14.0 7.2 3.5 8.1 0.0 5.0 6 1 0 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 CBY36571.1 - 0.091 13.3 9.3 1.5 9.4 0.0 5.6 6 1 0 6 6 6 0 HEAT-like repeat TAF6_C PF07571.13 CBY36571.1 - 0.14 12.5 0.1 4.5 7.7 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CBY36571.1 - 0.62 10.5 8.3 9.3 6.8 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 CBY36571.1 - 1.1 7.7 6.9 0.29 9.6 1.2 2.9 3 1 0 3 3 3 0 Adaptin N terminal region RPA_interact_N PF14766.6 CBY36572.1 - 1.6e-08 34.0 6.2 2.6e-08 33.3 6.2 1.3 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Cactin_mid PF10312.9 CBY36572.1 - 0.013 15.2 0.5 0.023 14.4 0.5 1.4 1 1 0 1 1 1 0 Conserved mid region of cactin RPA_interact_C PF14768.6 CBY36572.1 - 0.054 14.1 6.3 0.061 13.9 5.1 1.7 2 0 0 2 2 2 0 Replication protein A interacting C-terminal eIF-3c_N PF05470.12 CBY36573.1 - 1.7e-79 267.8 21.5 6.9e-78 262.4 15.9 3.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CBY36573.1 - 8.6e-13 48.7 0.2 2.5e-12 47.2 0.2 1.8 1 0 0 1 1 1 1 PCI domain DUF1132 PF06575.12 CBY36573.1 - 0.031 14.6 0.6 0.097 13.1 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) HNOBA PF07701.14 CBY36573.1 - 0.14 11.6 6.4 3.5 7.0 1.9 2.6 2 1 0 2 2 2 0 Heme NO binding associated Chlam_PMP PF02415.17 CBY36574.1 - 0.032 14.7 0.4 0.27 11.8 0.0 2.8 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DMAP1 PF05499.12 CBY36575.1 - 8.6e-26 90.8 2.2 2.1e-25 89.6 2.2 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CBY36575.1 - 1.2e-18 67.1 0.6 2.7e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ntox1 PF15500.6 CBY36575.1 - 0.011 16.1 1.4 0.022 15.1 1.4 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 HECT PF00632.25 CBY36576.1 - 3.9e-93 312.3 0.0 5.1e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY36576.1 - 5.6e-38 128.7 16.7 9.4e-13 48.0 5.9 3.7 3 0 0 3 3 3 3 WW domain DUF1971 PF09313.11 CBY36576.1 - 0.099 12.7 1.0 2.3 8.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1971) C2 PF00168.30 CBY36577.1 - 2.5e-18 66.3 0.1 2.5e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 C2 domain WW PF00397.26 CBY36577.1 - 1.8e-09 37.5 2.9 4e-09 36.4 2.9 1.6 1 0 0 1 1 1 1 WW domain YSIRK_signal PF04650.17 CBY36577.1 - 0.31 10.9 0.8 0.51 10.3 0.8 1.3 1 0 0 1 1 1 0 YSIRK type signal peptide Ras PF00071.22 CBY36578.1 - 1.2e-25 90.0 0.0 1.5e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY36578.1 - 4.8e-09 36.5 0.0 7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY36578.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY36578.1 - 7e-05 22.3 0.0 8.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 CBY36578.1 - 0.0012 18.0 0.1 0.3 10.2 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 CBY36578.1 - 0.0033 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 CBY36578.1 - 0.0059 16.7 0.1 0.026 14.6 0.1 2.1 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 CBY36578.1 - 0.028 13.8 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Mon1 PF03164.14 CBY36578.1 - 0.086 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Flavin_Reduct PF01613.18 CBY36578.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain AAA_14 PF13173.6 CBY36578.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cep57_CLD PF14073.6 CBY36579.1 - 3.6e-10 40.1 14.7 3.6e-10 40.1 14.7 3.7 2 2 0 3 3 3 1 Centrosome localisation domain of Cep57 ING PF12998.7 CBY36579.1 - 7.9 7.1 19.6 0.25 12.0 3.3 3.2 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding GCH_III PF05165.12 CBY36580.1 - 0.028 13.7 0.2 0.034 13.4 0.2 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III Sds3 PF08598.11 CBY36580.1 - 0.037 14.0 0.8 0.037 14.0 0.8 1.5 2 0 0 2 2 2 0 Sds3-like DUF1690 PF07956.11 CBY36580.1 - 0.12 12.8 12.2 1 9.8 12.2 2.1 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4600 PF15372.6 CBY36580.1 - 0.15 12.5 7.0 0.062 13.7 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF1664 PF07889.12 CBY36580.1 - 0.27 11.3 1.7 0.5 10.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF349 PF03993.12 CBY36580.1 - 1.3 9.4 13.8 0.68 10.3 2.4 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Remorin_C PF03763.13 CBY36580.1 - 1.8 8.5 9.3 0.37 10.7 5.8 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region DUF2870 PF11069.8 CBY36581.1 - 1.3e-40 137.6 1.4 2.7e-40 136.7 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.12 CBY36581.1 - 0.043 14.1 0.5 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 PSP1 C-terminal conserved region ubiquitin PF00240.23 CBY36581.1 - 0.081 12.7 0.3 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family Ras PF00071.22 CBY36582.1 - 9.5e-56 187.9 0.0 1.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY36582.1 - 2.6e-33 114.8 0.0 3.7e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY36582.1 - 1.8e-12 47.1 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY36582.1 - 4.2e-07 30.1 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY36582.1 - 0.00014 21.8 0.1 0.0041 17.0 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CBY36582.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY36582.1 - 0.00035 20.2 0.0 0.014 15.0 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY36582.1 - 0.0012 18.6 0.1 0.069 12.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY36582.1 - 0.0043 16.7 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBY36582.1 - 0.0063 16.8 0.1 0.031 14.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 CBY36582.1 - 0.0089 16.4 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 CBY36582.1 - 0.014 14.7 0.1 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 CBY36582.1 - 0.016 14.9 0.1 0.026 14.3 0.1 1.6 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 CBY36582.1 - 0.017 14.6 0.1 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CBY36582.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY36582.1 - 0.024 14.2 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CBY36582.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 CBY36582.1 - 0.044 13.7 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CBY36582.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CBY36582.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CBY36582.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Glyco_hydro_75 PF07335.11 CBY36582.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NB-ARC PF00931.22 CBY36582.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 CBY36582.1 - 0.2 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF3456 PF11938.8 CBY36583.1 - 6.7e-06 26.7 2.8 0.00046 20.7 0.7 2.8 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 CBY36583.1 - 0.00023 21.5 16.1 0.00023 21.5 16.1 3.9 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.24 CBY36583.1 - 0.0017 18.5 10.4 0.0017 18.5 10.4 4.5 2 1 2 4 4 4 1 Laminin EGF domain ALG3 PF05208.13 CBY36585.1 - 7.2e-38 130.9 4.2 8.4e-38 130.7 4.2 1.0 1 0 0 1 1 1 1 ALG3 protein DUF1295 PF06966.12 CBY36586.1 - 3.6e-21 75.8 0.2 4.4e-21 75.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CBY36586.1 - 5.4e-06 26.5 0.1 6.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CBY36586.1 - 0.011 16.1 0.6 0.022 15.1 0.6 1.6 1 1 0 1 1 1 0 Phospholipid methyltransferase ICMT PF04140.14 CBY36586.1 - 0.012 16.1 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FecCD PF01032.18 CBY36586.1 - 0.044 12.8 1.8 0.061 12.3 0.3 1.9 1 1 1 2 2 2 0 FecCD transport family ERG4_ERG24 PF01222.17 CBY36586.1 - 0.063 12.0 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF4207 PF13904.6 CBY36588.1 - 3.2e-10 40.1 64.7 5.4e-10 39.4 64.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) TP53IP5 PF15331.6 CBY36588.1 - 1.4 9.0 32.8 1.6 8.8 32.1 1.4 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SOBP PF15279.6 CBY36588.1 - 1.7 9.2 22.2 2.5 8.6 22.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.11 CBY36588.1 - 1.8 8.6 37.7 2.2 8.3 37.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UvrD-helicase PF00580.21 CBY36588.1 - 5.6 6.4 21.7 7.6 6.0 21.7 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain GREB1 PF15782.5 CBY36588.1 - 7 3.6 20.1 8.1 3.4 20.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Phospholip_A2_1 PF00068.19 CBY36589.1 - 2.7e-17 63.2 9.8 5.4e-17 62.3 9.8 1.5 1 0 0 1 1 1 1 Phospholipase A2 SMP_LBD PF17047.5 CBY36590.1 - 1.3e-08 34.5 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 CBY36591.1 - 2.3e-17 63.2 0.0 8.8e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain RNase_PH PF01138.21 CBY36592.1 - 1.7e-13 51.2 0.0 3.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Phospholip_A2_1 PF00068.19 CBY36593.1 - 1.5e-18 67.3 6.1 1.5e-18 67.3 6.1 1.5 2 0 0 2 2 2 1 Phospholipase A2 CPG4 PF15481.6 CBY36593.1 - 0.013 16.1 1.3 0.013 16.1 1.3 1.6 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 CUB PF00431.20 CBY36595.1 - 0 1294.3 69.2 1.1e-23 83.7 0.0 27.6 27 1 0 27 27 27 26 CUB domain EGF PF00008.27 CBY36595.1 - 8.9e-10 38.7 26.7 2.4e-07 30.9 10.1 9.9 9 0 0 9 9 9 5 EGF-like domain EGF_3 PF12947.7 CBY36595.1 - 0.00038 20.6 9.0 0.00038 20.6 9.0 8.9 7 1 1 8 8 8 5 EGF domain EGF_CA PF07645.15 CBY36595.1 - 0.0011 19.1 7.5 0.0011 19.1 7.5 9.4 6 3 3 9 9 9 3 Calcium-binding EGF domain hEGF PF12661.7 CBY36595.1 - 0.0024 18.4 10.4 0.0024 18.4 10.4 9.5 9 0 0 9 9 9 3 Human growth factor-like EGF CUB_2 PF02408.20 CBY36595.1 - 3.7 7.4 39.4 0.85 9.4 0.1 12.1 14 0 0 14 14 14 0 CUB-like domain DUF4065 PF13274.6 CBY36596.1 - 0.24 12.3 3.6 0.24 12.3 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) RasGEF PF00617.19 CBY36597.1 - 8.8e-05 22.8 0.7 0.00024 21.3 0.7 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CBY36597.1 - 0.00022 21.4 1.0 0.00075 19.7 0.1 2.3 2 1 0 2 2 2 1 RasGEF N-terminal motif DUF3636 PF12331.8 CBY36598.1 - 0.029 14.2 0.0 0.031 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Pkinase PF00069.25 CBY36599.1 - 1.5e-67 227.8 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36599.1 - 4.8e-43 147.3 0.0 5.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36599.1 - 4.3e-08 32.8 0.0 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY36599.1 - 0.005 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY36599.1 - 0.059 12.3 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBY36599.1 - 0.067 12.8 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 CBY36600.1 - 1.6e-21 76.2 0.0 8.3e-07 29.6 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36600.1 - 1.7e-09 37.8 0.0 0.00018 21.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 CBY36600.1 - 0.16 10.6 0.0 0.38 9.3 0.0 1.6 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Proteasome_A_N PF10584.9 CBY36600.1 - 0.21 11.3 0.6 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Katanin_con80 PF13925.6 CBY36601.1 - 2.2e-09 37.6 0.1 3.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 con80 domain of Katanin GFO_IDH_MocA PF01408.22 CBY36602.1 - 5.1e-20 72.5 0.0 7.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ASH PF15780.5 CBY36603.1 - 2.5e-20 72.5 2.8 2.9e-10 40.2 0.0 8.1 8 1 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBY36603.1 - 4.7e-10 39.6 2.5 0.073 13.3 0.1 6.3 6 1 0 6 6 6 2 Transmembrane protein 131-like PapD-like PF14874.6 CBY36603.1 - 7.2e-10 39.0 1.2 0.026 14.7 0.0 5.4 6 0 0 6 6 6 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CBY36603.1 - 1.5e-05 24.8 1.4 2.7 7.9 0.1 6.4 6 1 0 6 6 6 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY36603.1 - 0.0036 17.3 0.9 24 5.1 0.0 5.6 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) Securin PF04856.13 CBY36603.1 - 0.98 9.3 8.9 0.086 12.8 2.2 2.3 1 1 1 2 2 2 0 Securin sister-chromatid separation inhibitor Lectin_C PF00059.21 CBY36604.1 - 8.7e-16 58.6 4.6 1e-15 58.4 2.5 1.9 2 0 0 2 2 2 1 Lectin C-type domain Cnd1 PF12717.7 CBY36605.1 - 0.00037 20.6 1.3 0.0029 17.7 1.1 2.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY36605.1 - 0.00094 19.2 1.0 0.17 12.3 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat CLASP_N PF12348.8 CBY36605.1 - 0.0057 16.2 0.3 0.38 10.3 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal DUF3361 PF11841.8 CBY36605.1 - 0.0078 16.2 0.3 0.75 9.7 0.0 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) Cohesin_HEAT PF12765.7 CBY36605.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Spore_III_AE PF09546.10 CBY36606.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) DEAD PF00270.29 CBY36607.1 - 5.7e-08 32.7 0.0 8.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5006 PF16397.5 CBY36607.1 - 0.018 14.3 0.8 3.4 6.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5006) RVT_1 PF00078.27 CBY36608.1 - 2.7e-20 72.9 0.0 3.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPV_P10 PF05531.12 CBY36609.1 - 0.13 12.7 0.3 0.3 11.6 0.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 CBY36609.1 - 0.2 11.4 8.1 9.1 6.1 5.1 2.8 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 CBY36609.1 - 1.9 9.2 6.4 1.3 9.7 2.9 2.4 2 0 0 2 2 2 0 Initiation control protein YabA CAP PF00188.26 CBY36610.1 - 2.2e-30 106.1 0.2 8.1e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family SOAR PF16533.5 CBY36610.1 - 0.096 12.7 1.7 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region CT_A_B PF02626.15 CBY36610.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B Homeodomain PF00046.29 CBY36614.1 - 1.3e-23 82.6 4.7 2.1e-23 81.9 4.7 1.3 1 0 0 1 1 1 1 Homeodomain GAIN_A PF18619.1 CBY36614.1 - 0.093 13.0 0.7 0.3 11.3 0.2 2.0 1 1 1 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Troponin PF00992.20 CBY36615.1 - 5.9e-25 88.1 48.9 5.9e-21 75.2 40.5 2.9 2 1 1 3 3 3 2 Troponin PAS_10 PF13596.6 CBY36615.1 - 9.6 6.9 7.8 28 5.4 0.6 3.0 2 1 1 3 3 3 0 PAS domain FAD_binding_3 PF01494.19 CBY36616.1 - 7.5e-13 48.4 0.0 7.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CBY36616.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Sulfotransfer_2 PF03567.14 CBY36618.1 - 3.5e-26 92.6 0.4 5.8e-26 91.9 0.4 1.3 1 0 0 1 1 1 1 Sulfotransferase family Phospholip_A2_1 PF00068.19 CBY36619.1 - 1.2e-17 64.4 10.2 1.2e-17 64.4 10.2 1.7 2 0 0 2 2 2 1 Phospholipase A2 TGF_beta_GS PF08515.12 CBY36619.1 - 0.7 9.4 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif EF-hand_7 PF13499.6 CBY36620.1 - 9.7e-07 29.2 5.4 0.0025 18.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY36620.1 - 1.9e-05 24.2 5.2 0.068 13.1 0.4 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY36620.1 - 0.00025 20.4 7.9 0.14 11.8 0.3 3.6 4 0 0 4 4 4 2 EF hand Syntaxin_2 PF14523.6 CBY36620.1 - 0.038 14.3 1.7 1.4 9.4 0.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein EF-hand_8 PF13833.6 CBY36620.1 - 0.12 12.2 2.6 5.8 6.8 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain pair V-SNARE_C PF12352.8 CBY36620.1 - 0.25 11.7 2.2 1 9.7 0.6 2.5 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Cep57_CLD_2 PF14197.6 CBY36620.1 - 0.27 11.4 4.0 0.18 11.9 1.2 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 EF-hand_5 PF13202.6 CBY36620.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.8 3 0 0 3 3 3 0 EF hand Phospholip_A2_1 PF00068.19 CBY36621.1 - 1.4e-15 57.7 4.4 2.8e-15 56.7 4.4 1.5 1 0 0 1 1 1 1 Phospholipase A2 DUF4710 PF15828.5 CBY36622.1 - 0.0022 18.1 1.0 0.0065 16.6 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4710) Chalcone_3 PF16036.5 CBY36622.1 - 0.0048 17.0 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone isomerase-like Pyr_redox_2 PF07992.14 CBY36624.1 - 1e-44 152.9 0.1 1.3e-44 152.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 CBY36624.1 - 5.3e-37 127.1 2.7 1.3e-21 77.3 0.1 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 CBY36624.1 - 1.4e-12 48.0 0.1 3.8e-10 40.2 0.4 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBY36624.1 - 1.2e-08 34.6 0.0 4.3e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBY36624.1 - 5.2e-07 29.8 0.0 0.00063 19.8 0.0 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CBY36624.1 - 7.5e-06 25.5 0.1 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 CBY36624.1 - 1.8e-05 24.1 0.0 0.0022 17.2 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CBY36624.1 - 0.0001 22.0 1.2 0.013 15.1 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CBY36624.1 - 0.0059 17.0 0.2 0.19 12.2 0.0 2.8 3 1 1 4 4 4 1 Putative NAD(P)-binding Thi4 PF01946.17 CBY36624.1 - 0.008 15.4 0.6 0.61 9.3 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Reductase_C PF14759.6 CBY36624.1 - 0.011 16.3 0.0 0.084 13.4 0.0 2.4 2 0 0 2 2 2 0 Reductase C-terminal HI0933_like PF03486.14 CBY36624.1 - 0.02 13.6 0.0 0.05 12.3 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 CBY36624.1 - 0.1 11.7 0.2 3.3 6.7 0.1 2.7 2 1 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CBY36624.1 - 0.11 12.8 0.3 30 4.9 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 CBY36625.1 - 1.6e-14 53.9 0.0 3.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36625.1 - 1.1e-12 47.8 0.0 2.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 CBY36625.1 - 0.00025 21.2 0.1 0.00073 19.7 0.1 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain NARP1 PF12569.8 CBY36626.1 - 1.3e-148 496.2 27.8 5.2e-147 490.9 20.9 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CBY36626.1 - 1.1e-14 53.3 19.5 0.0047 16.9 0.1 9.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36626.1 - 2.1e-10 39.9 22.3 0.023 14.9 0.1 10.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY36626.1 - 7.4e-10 38.2 16.6 0.038 13.8 0.3 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36626.1 - 6.2e-08 32.8 13.0 1.9 8.9 0.0 7.9 6 2 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36626.1 - 1e-07 32.1 18.2 0.025 14.8 0.7 5.7 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY36626.1 - 8.8e-07 29.3 9.2 0.0098 16.4 0.2 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36626.1 - 1.8e-06 28.3 3.2 24 6.1 0.0 8.5 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36626.1 - 4e-06 27.4 0.9 3.2 8.5 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY36626.1 - 0.00082 18.7 5.1 0.025 13.8 0.8 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36626.1 - 0.0038 16.9 11.8 0.0053 16.4 0.2 4.4 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 CBY36626.1 - 0.0057 17.2 0.7 52 4.9 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBY36626.1 - 0.0096 16.0 0.9 0.053 13.6 0.1 2.7 2 1 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_17 PF13431.6 CBY36626.1 - 0.028 14.8 2.5 2.6 8.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY36626.1 - 0.073 13.2 3.4 0.17 12.0 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Pullulanase_Ins PF18494.1 CBY36626.1 - 0.14 12.6 0.1 0.91 10.0 0.0 2.5 2 0 0 2 2 1 0 Pullulanase Ins domain U79_P34 PF03064.16 CBY36626.1 - 0.56 9.5 9.3 1.3 8.3 9.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Fis1_TPR_C PF14853.6 CBY36626.1 - 1.1 9.3 6.6 1.8 8.7 0.0 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF4298 PF14131.6 CBY36626.1 - 1.5 8.8 6.4 2.3 8.3 1.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) TPR_10 PF13374.6 CBY36626.1 - 1.7 8.6 9.4 1.8 8.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36626.1 - 1.9 9.3 11.0 89 4.1 0.1 6.8 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF4288 PF14119.6 CBY36626.1 - 3.8 8.0 7.4 0.54 10.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Sybindin PF04099.12 CBY36627.1 - 1.2e-18 67.4 0.0 1.2e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBY36627.1 - 0.057 13.5 0.1 0.069 13.3 0.1 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region ArgoMid PF16487.5 CBY36628.1 - 1.6e-33 114.8 0.7 4.1e-33 113.5 0.1 2.1 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 CBY36628.1 - 4.8e-31 108.2 0.0 9.5e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY36628.1 - 2.1e-24 85.9 0.1 3.8e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY36628.1 - 4.2e-23 80.8 0.1 8.7e-23 79.8 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY36628.1 - 8.2e-15 54.9 0.0 2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Piwi PF02171.17 CBY36628.1 - 1.6e-13 50.6 0.6 2.3e-13 50.0 0.6 1.3 1 0 0 1 1 1 1 Piwi domain Rhomboid PF01694.22 CBY36630.1 - 2.5e-29 102.2 13.9 2.5e-29 102.2 13.9 1.4 2 0 0 2 2 2 1 Rhomboid family IL15 PF02372.15 CBY36631.1 - 0.062 13.3 1.1 0.09 12.8 0.2 1.6 2 0 0 2 2 2 0 Interleukin 15 Exonuc_VII_S PF02609.16 CBY36631.1 - 1.2 9.2 4.7 3.7 7.7 0.3 2.5 2 1 0 2 2 2 0 Exonuclease VII small subunit zf-C4 PF00105.18 CBY36633.1 - 7.3e-39 132.1 22.3 4.7e-26 91.0 12.1 2.0 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY36633.1 - 0.00044 20.5 20.3 0.01 16.1 0.6 3.5 2 1 0 3 3 3 2 C1 domain Clavanin PF05452.11 CBY36633.1 - 0.0014 18.7 0.0 1.2 9.3 0.0 2.1 1 1 1 2 2 2 2 Clavanin ssDBP_DBD PF18361.1 CBY36633.1 - 0.032 14.3 0.6 1.7 8.8 0.1 2.1 1 1 1 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain Pox_A30L_A26L PF06086.12 CBY36633.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein zf-RRPl_C4 PF17026.5 CBY36633.1 - 0.44 10.7 7.6 8 6.6 3.6 2.2 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Anti-TRAP PF15777.5 CBY36633.1 - 1.9 8.5 7.8 6.9 6.7 0.1 2.6 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein ZF-HD_dimer PF04770.12 CBY36633.1 - 3 8.2 16.6 2.1 8.7 2.7 3.0 1 1 1 2 2 2 0 ZF-HD protein dimerisation region Peptidase_C48 PF02902.19 CBY36634.1 - 4.7e-08 33.1 10.7 7e-07 29.3 0.4 3.3 4 1 1 5 5 5 2 Ulp1 protease family, C-terminal catalytic domain DUF4530 PF15039.6 CBY36635.1 - 0.0033 17.6 0.5 0.0053 16.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) Terminase_4 PF05119.12 CBY36635.1 - 0.025 15.0 0.4 0.067 13.6 0.3 1.7 2 0 0 2 2 2 0 Phage terminase, small subunit PPV_E2_N PF00508.17 CBY36635.1 - 0.08 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal CENP-H PF05837.12 CBY36635.1 - 0.099 13.1 5.5 0.19 12.2 5.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NIF PF03031.18 CBY36636.1 - 2.3e-49 167.1 0.1 2.9e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SSXRD PF09514.10 CBY36636.1 - 0.045 13.4 0.5 0.084 12.5 0.5 1.5 1 0 0 1 1 1 0 SSXRD motif Elongin_A PF06881.11 CBY36637.1 - 1.1e-10 41.9 0.5 1.1e-10 41.9 0.5 4.9 4 2 0 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2852 PF11014.8 CBY36638.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Ada3 PF10198.9 CBY36640.1 - 0.0022 18.1 5.3 0.0041 17.3 5.4 1.4 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 TetR_C_37 PF18665.1 CBY36640.1 - 0.01 16.4 0.2 0.075 13.7 0.0 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Dzip-like_N PF13815.6 CBY36640.1 - 0.024 14.6 1.6 0.024 14.6 1.6 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CSF-1 PF05337.11 CBY36640.1 - 0.05 13.7 0.3 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Apolipoprotein PF01442.18 CBY36640.1 - 0.094 12.6 7.3 0.073 12.9 5.7 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1690 PF07956.11 CBY36640.1 - 7.6 7.0 9.4 75 3.7 8.1 2.9 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Fer4_11 PF13247.6 CBY36641.1 - 0.036 14.2 1.6 0.23 11.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Alk_phosphatase PF00245.20 CBY36642.1 - 3.5e-94 316.1 4.4 5.9e-94 315.4 4.4 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 CBY36642.1 - 9.6e-06 25.2 0.0 2.8e-05 23.7 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 CBY36642.1 - 0.00028 20.3 0.8 0.00055 19.4 0.8 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 CBY36642.1 - 0.015 14.9 0.8 0.033 13.8 0.8 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase VasI PF11319.8 CBY36642.1 - 0.056 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 Phospholip_A2_1 PF00068.19 CBY36643.1 - 1.3e-15 57.8 6.1 1.3e-15 57.8 6.1 1.6 2 0 0 2 2 2 1 Phospholipase A2 Trypsin PF00089.26 CBY36644.1 - 7.4e-36 124.0 0.0 3.7e-35 121.7 0.0 2.0 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY36644.1 - 4.8e-21 75.1 0.1 1.1e-20 74.1 0.1 1.6 1 0 0 1 1 1 1 CUB domain CUB_2 PF02408.20 CBY36644.1 - 0.074 12.8 0.1 0.19 11.5 0.1 1.8 1 1 0 1 1 1 0 CUB-like domain NPV_P10 PF05531.12 CBY36645.1 - 0.13 12.7 0.1 0.45 11.0 0.0 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sulfatase PF00884.23 CBY36647.1 - 5.5e-34 118.0 1.2 2.7e-33 115.7 0.1 1.9 1 1 1 2 2 2 2 Sulfatase RNA_pol_Rpb2_6 PF00562.28 CBY36648.1 - 5.1e-100 335.3 0.0 1.2e-99 334.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBY36648.1 - 1.2e-31 109.9 0.2 2.1e-31 109.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CBY36648.1 - 1.3e-25 89.3 0.0 3.1e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBY36648.1 - 1e-17 64.3 0.0 3.2e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CBY36648.1 - 1.7e-14 53.5 0.0 3.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CBY36648.1 - 0.0015 18.2 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Pox_A6 PF04924.12 CBY36648.1 - 0.021 13.8 0.3 0.039 12.9 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A6 protein Ank_2 PF12796.7 CBY36650.1 - 7.8e-22 77.7 0.1 1.5e-06 28.7 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY36650.1 - 1.6e-17 63.3 0.1 6.9e-06 26.2 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY36650.1 - 7.8e-17 61.4 1.1 1.7e-08 34.9 0.0 5.4 3 3 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY36650.1 - 1.3e-15 57.0 0.9 0.00037 20.8 0.1 5.9 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CBY36650.1 - 3.4e-14 51.6 0.0 0.0037 17.6 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat PEGA PF08308.11 CBY36650.1 - 0.0067 16.3 0.0 1.3 9.0 0.0 3.0 3 0 0 3 3 3 1 PEGA domain Sushi PF00084.20 CBY36651.1 - 0.049 14.2 1.8 0.049 14.2 1.8 2.9 1 1 2 3 3 3 0 Sushi repeat (SCR repeat) DUF5037 PF16440.5 CBY36652.1 - 0.17 11.4 0.8 0.45 10.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5037) Phospholip_A2_1 PF00068.19 CBY36653.1 - 9.6e-14 51.8 3.3 9.6e-14 51.8 3.3 2.0 2 0 0 2 2 2 1 Phospholipase A2 Pkinase_Tyr PF07714.17 CBY36654.1 - 4.2e-75 252.4 0.1 5.7e-75 251.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36654.1 - 3.6e-41 141.3 0.0 5.2e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CBY36654.1 - 0.04 13.8 0.0 0.34 10.8 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY36654.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Phospholip_A2_1 PF00068.19 CBY36655.1 - 2.9e-18 66.4 10.6 4.9e-18 65.6 10.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 RRM_1 PF00076.22 CBY36656.1 - 5.7e-10 38.9 0.4 0.0038 17.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAR_2 PF10455.9 CBY36656.1 - 0.022 13.9 4.9 0.043 12.9 4.9 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4283 PF14111.6 CBY36656.1 - 0.092 12.3 0.0 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) BRAP2 PF07576.12 CBY36656.1 - 0.14 12.4 0.5 0.5 10.6 0.5 2.0 1 1 0 1 1 1 0 BRCA1-associated protein 2 PV-1 PF06637.11 CBY36657.1 - 0.0023 16.8 3.7 0.0038 16.1 3.7 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) Exonuc_VII_L PF02601.15 CBY36657.1 - 0.57 9.7 2.9 0.88 9.1 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Trypsin PF00089.26 CBY36658.1 - 7.3e-37 127.3 0.4 7.7e-27 94.5 0.1 4.4 2 2 0 2 2 2 2 Trypsin Shugoshin_N PF07558.11 CBY36659.1 - 0.018 14.9 2.7 0.09 12.7 0.6 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GMP_PDE_delta PF05351.11 CBY36659.1 - 0.041 14.0 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 GMP-PDE, delta subunit Peptidase_S66 PF02016.15 CBY36659.1 - 0.044 13.9 0.2 0.13 12.4 0.1 1.8 2 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain Trimer_CC PF08954.11 CBY36659.1 - 0.51 9.9 3.6 0.21 11.2 0.7 1.8 2 0 0 2 2 2 0 Trimerisation motif ZapB PF06005.12 CBY36659.1 - 1.3 9.5 8.1 0.12 12.9 2.0 2.3 2 1 1 3 3 3 0 Cell division protein ZapB Histone_H2A_C PF16211.5 CBY36660.1 - 3.4e-17 61.9 2.1 7.8e-17 60.7 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY36660.1 - 2.4e-16 60.3 0.0 3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36660.1 - 2.4e-05 24.5 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY36661.1 - 2.2e-17 63.6 0.1 2.7e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36661.1 - 0.00013 22.2 0.1 0.0003 21.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY36661.1 - 0.0049 17.3 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY36661.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-T_C PF15511.6 CBY36662.1 - 4.1e-08 33.3 0.1 5.5e-08 32.9 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY36662.1 - 6.6e-05 23.0 0.2 0.00012 22.1 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY36662.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY36662.1 - 0.00079 19.7 1.0 0.0029 17.9 0.1 2.0 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY36662.1 - 0.0013 19.1 0.5 0.0027 18.1 0.5 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY36662.1 - 0.036 14.2 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zinc_ribbon_16 PF17034.5 CBY36663.1 - 5.1e-08 33.2 15.3 9.9e-08 32.2 15.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family DUF3565 PF12088.8 CBY36663.1 - 0.089 12.8 2.9 0.13 12.2 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) zf-rbx1 PF12678.7 CBY36663.1 - 6.6 7.1 16.1 0.32 11.3 8.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain Pkinase PF00069.25 CBY36664.1 - 3.3e-27 95.5 0.0 6.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36664.1 - 3.1e-21 75.8 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36664.1 - 0.00024 20.5 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Presenilin PF01080.17 CBY36664.1 - 0.0013 17.5 7.3 0.0017 17.2 7.3 1.1 1 0 0 1 1 1 1 Presenilin Kdo PF06293.14 CBY36664.1 - 0.04 13.3 0.2 0.098 12.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SOG2 PF10428.9 CBY36664.1 - 3.4 6.7 18.1 4.9 6.2 18.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 CBY36664.1 - 9.9 5.1 12.9 15 4.5 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SRI PF08236.11 CBY36665.1 - 0.0051 17.0 7.6 0.0059 16.7 7.6 1.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain EXS PF03124.14 CBY36666.1 - 1.2e-76 258.2 22.2 1.7e-76 257.7 22.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CBY36666.1 - 1.2e-25 91.3 13.2 3.3e-15 56.9 6.4 2.3 1 1 1 2 2 2 2 SPX domain PrgI PF12666.7 CBY36666.1 - 8.6 7.1 13.0 2.6 8.8 3.8 3.0 2 0 0 2 2 2 0 PrgI family protein CH PF00307.31 CBY36667.1 - 1.3e-16 60.7 0.0 2.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CBY36667.1 - 6.3e-13 48.1 3.5 6.3e-13 48.1 3.5 1.9 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.11 CBY36667.1 - 0.0093 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 CBY36667.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Sulfatase PF00884.23 CBY36668.1 - 7e-59 199.7 1.0 9.5e-59 199.3 1.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY36668.1 - 3.4e-06 26.9 0.1 4.6e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY36668.1 - 0.13 12.2 0.5 0.55 10.2 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF1501 PF07394.12 CBY36668.1 - 0.14 11.2 0.1 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) CUB PF00431.20 CBY36669.1 - 7.6e-10 39.1 0.2 1.3e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 CUB domain Adeno_E3_CR1 PF02440.15 CBY36669.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 PT PF04886.12 CBY36670.1 - 0.0085 15.6 7.8 0.0085 15.6 7.8 2.5 2 0 0 2 2 2 1 PT repeat Mur_ligase_M PF08245.12 CBY36670.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Mur ligase middle domain Mucin PF01456.17 CBY36670.1 - 0.31 11.0 18.5 0.52 10.3 18.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ASFV_J13L PF05568.11 CBY36670.1 - 4.1 7.1 10.3 6.7 6.4 10.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein KH_1 PF00013.29 CBY36671.1 - 3.1e-15 55.7 0.4 5.3e-15 55.0 0.4 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CBY36671.1 - 3.9e-05 23.4 0.1 6.9e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 KH domain ATP-gua_Ptrans PF00217.19 CBY36672.1 - 1.7e-57 194.4 0.0 2.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY36672.1 - 4.1e-23 81.6 0.0 7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Ion_trans PF00520.31 CBY36673.1 - 9.9e-78 260.7 23.3 2.7e-58 197.1 8.7 2.2 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CBY36673.1 - 0.0032 16.2 1.1 0.0032 16.2 1.1 3.8 3 1 1 4 4 4 3 Polycystin cation channel DUF2975 PF11188.8 CBY36673.1 - 0.1 12.5 4.5 0.18 11.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF2556 PF10831.8 CBY36673.1 - 0.59 10.1 0.0 0.59 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) DPM3 PF08285.11 CBY36673.1 - 0.7 10.1 3.1 17 5.7 0.2 2.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Lactamase_B_6 PF16661.5 CBY36674.1 - 1.4e-09 37.7 0.1 2.6e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 CBY36674.1 - 1.2e-06 28.8 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 CBY36674.1 - 1.6e-05 24.3 0.1 2.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family RRM_1 PF00076.22 CBY36675.1 - 6.2e-32 109.2 0.0 1.4e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF667 PF05018.13 CBY36676.1 - 1.7e-27 96.3 0.0 2.7e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF667) WD40 PF00400.32 CBY36676.1 - 0.0012 19.7 9.8 17 6.5 0.0 7.2 8 1 0 8 8 8 1 WD domain, G-beta repeat PQQ_3 PF13570.6 CBY36676.1 - 0.14 12.7 0.0 3.4 8.3 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain MutL_C PF08676.11 CBY36677.1 - 2.3e-23 82.6 0.0 4.1e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CBY36677.1 - 6.6e-22 77.4 0.1 2.1e-21 75.8 0.1 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Galactosyl_T PF01762.21 CBY36678.1 - 1.4e-07 31.5 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Sema PF01403.19 CBY36679.1 - 2.4e-06 26.7 0.0 3.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Sema domain Podoplanin PF05808.11 CBY36679.1 - 0.072 13.2 0.2 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Podoplanin FAM104 PF15434.6 CBY36679.1 - 0.095 13.3 2.5 0.15 12.6 0.1 2.4 2 0 0 2 2 2 0 Family 104 PSI PF01437.25 CBY36679.1 - 0.14 12.7 5.3 0.32 11.6 5.3 1.5 1 0 0 1 1 1 0 Plexin repeat zf-C4_ClpX PF06689.13 CBY36680.1 - 0.0035 17.2 3.5 0.0035 17.2 3.5 2.3 2 0 0 2 2 1 1 ClpX C4-type zinc finger zf-C3HC4_3 PF13920.6 CBY36680.1 - 0.0041 17.0 10.5 0.0041 17.0 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY36680.1 - 0.014 15.7 12.6 0.014 15.7 12.6 2.1 2 0 0 2 2 2 0 Ring finger domain Caudo_TAP PF02413.17 CBY36680.1 - 0.021 15.0 6.3 0.044 13.9 6.3 1.7 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Ten1_2 PF15490.6 CBY36680.1 - 0.051 13.3 0.2 0.076 12.7 0.2 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit MDM10 PF12519.8 CBY36680.1 - 0.36 9.7 5.0 0.44 9.4 5.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 zf-C3HC4_2 PF13923.6 CBY36680.1 - 0.4 10.6 15.5 0.28 11.1 13.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) V-ATPase_G_2 PF16999.5 CBY36680.1 - 1.5 9.3 11.4 0.3 11.5 6.3 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit HIP1_clath_bdg PF16515.5 CBY36680.1 - 2.4 8.8 17.5 0.69 10.6 6.5 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FYVE PF01363.21 CBY36680.1 - 2.5 8.3 14.8 22 5.3 14.8 2.5 1 1 0 1 1 1 0 FYVE zinc finger USP8_interact PF08941.10 CBY36680.1 - 2.7 7.8 6.1 0.41 10.4 1.7 1.8 2 0 0 2 2 2 0 USP8 interacting zf-RING_5 PF14634.6 CBY36680.1 - 4.5 7.3 20.4 0.38 10.8 13.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY36680.1 - 4.8 7.1 19.9 0.18 11.7 13.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.21 CBY36681.1 - 2.6e-18 65.8 13.3 4e-18 65.3 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY36681.1 - 8.7e-08 32.1 12.2 1.5e-07 31.3 12.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY36681.1 - 0.0002 21.8 3.4 0.00028 21.3 3.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Rh5 PF18515.1 CBY36681.1 - 0.012 15.0 0.9 0.015 14.6 0.9 1.1 1 0 0 1 1 1 0 Rh5 coiled-coil domain Pkinase PF00069.25 CBY36682.1 - 2e-39 135.6 0.0 2.5e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36682.1 - 5.7e-23 81.5 0.0 7.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36682.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 CBY36682.1 - 0.0015 19.2 2.3 0.003 18.2 2.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CBY36682.1 - 0.059 12.3 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY36682.1 - 0.13 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 CBY36683.1 - 5 7.0 30.3 7.3 6.5 30.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP72 PF08492.12 CBY36684.1 - 1.5e-09 38.1 10.9 1.5e-09 38.1 10.9 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 CBY36684.1 - 6.8e-09 36.1 10.3 0.0018 18.8 0.2 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36684.1 - 1.4e-06 28.6 3.3 0.095 13.6 0.1 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36684.1 - 0.00087 19.5 6.9 0.0076 16.5 0.1 4.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36684.1 - 0.039 14.1 7.0 34 4.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat HK_sensor PF16750.5 CBY36684.1 - 0.079 13.3 0.4 0.32 11.3 0.2 2.2 2 1 0 2 2 2 0 Sensor domain of 2-component histidine kinase TPR_8 PF13181.6 CBY36684.1 - 0.26 11.6 7.9 13 6.3 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.6 CBY36685.1 - 6.7e-10 38.9 20.0 4.4e-05 23.7 1.1 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY36685.1 - 4.4e-08 33.3 19.3 0.0025 18.5 1.3 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY36685.1 - 1.4e-05 25.3 22.1 0.002 18.5 1.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY36685.1 - 0.03 14.6 17.8 0.09 13.1 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_6 PF18450.1 CBY36685.1 - 0.048 13.4 0.4 0.048 13.4 0.4 2.6 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2_3rep PF18868.1 CBY36685.1 - 0.054 14.2 13.2 0.45 11.2 1.6 3.9 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CBY36685.1 - 0.18 12.2 9.2 0.17 12.4 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PyrI_C PF02748.15 CBY36685.1 - 7.1 6.6 17.6 3.5 7.6 0.6 4.0 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain C1_4 PF07975.12 CBY36685.1 - 9.9 6.5 10.6 28 5.0 2.9 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain GST_C_3 PF14497.6 CBY36686.1 - 3e-16 59.4 0.0 6.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY36686.1 - 2.3e-10 40.7 0.0 4.7e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY36686.1 - 3.6e-08 33.5 0.0 6.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY36686.1 - 0.00061 19.8 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CBY36686.1 - 0.047 14.4 0.0 0.27 12.0 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GPCR_chapero_1 PF11904.8 CBY36688.1 - 2.1e-70 237.6 0.2 3e-70 237.1 0.2 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_4 PF13637.6 CBY36688.1 - 1.1e-11 45.0 0.0 3.2e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY36688.1 - 1.4e-11 44.8 0.0 6.7e-09 36.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY36688.1 - 1.4e-10 41.1 0.0 9.5e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CBY36688.1 - 7.9e-10 38.8 0.1 9e-09 35.4 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY36688.1 - 1.6e-09 37.2 0.0 3.4e-05 23.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Phenol_hyd_sub PF06099.11 CBY36688.1 - 0.082 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Phenol hydroxylase subunit Sulfotransfer_2 PF03567.14 CBY36690.1 - 1.7e-24 87.1 2.4 3.4e-24 86.1 2.4 1.5 1 0 0 1 1 1 1 Sulfotransferase family SSF PF00474.17 CBY36691.1 - 3.2e-122 408.3 16.1 4.9e-122 407.7 16.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Nitr_red_assoc PF09655.10 CBY36691.1 - 0.0073 16.9 1.4 0.012 16.2 1.4 1.2 1 0 0 1 1 1 1 Conserved nitrate reductase-associated protein (Nitr_red_assoc) GAPT PF11770.8 CBY36691.1 - 1.3 8.8 4.6 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Ras PF00071.22 CBY36692.1 - 5e-45 153.0 0.0 9.1e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY36692.1 - 3.1e-27 95.2 0.0 8.8e-27 93.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY36692.1 - 3.9e-17 62.2 0.1 3.9e-17 62.2 0.1 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 CBY36692.1 - 5.8e-07 29.2 0.1 1.7e-05 24.4 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CBY36692.1 - 7.7e-06 25.4 1.8 1.6e-05 24.4 0.0 2.3 2 1 0 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY36692.1 - 4e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY36692.1 - 5.3e-05 23.2 1.5 0.086 12.7 0.0 2.9 2 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 CBY36692.1 - 0.00084 18.8 0.0 0.00084 18.8 0.0 3.1 2 2 1 3 3 3 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY36692.1 - 0.0054 16.3 0.1 0.034 13.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBY36692.1 - 0.02 14.3 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein bMG3 PF11974.8 CBY36692.1 - 0.097 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain DUF3726 PF12525.8 CBY36692.1 - 0.14 12.3 0.6 2.3 8.4 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3726) PTR2 PF00854.21 CBY36693.1 - 5.2e-95 318.6 11.5 3e-83 279.9 0.7 2.9 2 1 1 3 3 3 2 POT family PMP22_Claudin PF00822.20 CBY36693.1 - 0.022 14.6 0.3 0.022 14.6 0.3 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Kelch_1 PF01344.25 CBY36694.1 - 2.5e-45 151.8 10.4 5.4e-10 38.7 0.7 5.5 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CBY36694.1 - 3.2e-30 103.4 2.5 1.1e-06 28.7 0.0 5.7 4 2 1 5 5 5 5 Kelch motif BTB PF00651.31 CBY36694.1 - 1.1e-28 99.7 0.0 1.6e-27 95.9 0.0 2.3 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 CBY36694.1 - 7.4e-25 86.7 1.5 2.8e-05 24.3 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY36694.1 - 1.8e-17 62.5 7.4 0.0044 16.9 0.0 6.0 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CBY36694.1 - 6.9e-17 61.2 0.1 0.00077 19.4 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY36694.1 - 1.9e-11 43.6 7.7 0.025 14.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Peptidase_C47 PF05543.13 CBY36694.1 - 0.00013 21.6 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Staphopain peptidase C47 Glyco_hydro_31 PF01055.26 CBY36695.1 - 1.4e-135 452.9 9.0 2.1e-135 452.4 9.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CBY36695.1 - 8.5e-22 77.5 0.3 1.8e-21 76.5 0.3 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase RVT_1 PF00078.27 CBY36697.1 - 3.1e-31 108.6 0.1 1e-30 106.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_HK97_TLTM PF06120.11 CBY36697.1 - 0.014 14.6 3.1 0.06 12.5 3.1 2.1 1 0 0 1 1 1 0 Tail length tape measure protein LPMO_10 PF03067.15 CBY36699.1 - 6.3e-34 118.3 0.3 7.9e-34 118.0 0.3 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY36699.1 - 1e-10 41.6 1.5 4.1e-10 39.7 1.5 2.1 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain MBG PF17883.1 CBY36700.1 - 0.0055 17.3 0.4 0.0055 17.3 0.4 3.1 3 1 0 3 3 3 1 MBG domain Skp1 PF01466.19 CBY36700.1 - 0.05 13.7 1.3 0.19 11.9 1.3 2.0 1 0 0 1 1 1 0 Skp1 family, dimerisation domain GlcNAc_2-epim PF07221.11 CBY36700.1 - 0.24 10.6 2.4 0.14 11.4 0.4 1.6 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF4901 PF16244.5 CBY36702.1 - 0.14 11.5 0.6 0.18 11.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) PET117 PF15786.5 CBY36702.1 - 0.23 11.8 2.4 0.18 12.1 0.8 1.7 1 1 1 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial BRO1 PF03097.18 CBY36703.1 - 4.2e-23 81.8 3.4 4.9e-23 81.6 3.4 1.1 1 0 0 1 1 1 1 BRO1-like domain Lipoprotein_10 PF03202.13 CBY36703.1 - 0.28 11.6 3.1 0.12 12.8 0.5 1.7 2 1 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Peptidase_S28 PF05577.12 CBY36704.1 - 8.8e-42 143.4 0.7 3.4e-31 108.5 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Myelin_PLP PF01275.19 CBY36705.1 - 1.1e-22 81.1 9.5 3.4e-18 66.4 0.1 2.2 2 0 0 2 2 2 2 Myelin proteolipid protein (PLP or lipophilin) Gas_vesicle_C PF01304.17 CBY36705.1 - 0.43 10.6 2.1 2.6 8.1 1.6 2.1 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain Anoctamin PF04547.12 CBY36706.1 - 7e-126 420.7 14.5 8.6e-126 420.4 14.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 CBY36706.1 - 2e-35 122.6 1.8 3.4e-35 121.8 1.8 1.3 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Nudc_N PF14050.6 CBY36707.1 - 1.4e-17 63.4 0.1 2.9e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 CBY36707.1 - 8.9e-16 58.7 2.7 1.6e-15 57.9 2.7 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 CBY36708.1 - 1.9e-16 59.6 0.1 4e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CBY36708.1 - 1.8e-13 51.0 0.1 3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.6 CBY36708.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC15 PF15243.6 CBY36708.1 - 1.8 9.0 6.6 20 5.6 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 Apt1 PF10351.9 CBY36708.1 - 2.8 6.7 15.6 3.4 6.4 15.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SNF PF00209.18 CBY36709.1 - 4.6e-16 58.6 4.8 5.8e-16 58.3 4.8 1.1 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4064 PF13273.6 CBY36709.1 - 0.79 10.0 3.8 5.4 7.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Trypsin PF00089.26 CBY36712.1 - 5.7e-44 150.5 3.8 6.4e-44 150.4 3.8 1.0 1 0 0 1 1 1 1 Trypsin MCPsignal PF00015.21 CBY36714.1 - 0.4 10.5 12.5 1.9 8.3 12.5 1.8 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_II PF06009.12 CBY36714.1 - 0.58 10.2 10.3 0.88 9.6 10.1 1.4 1 1 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.8 CBY36714.1 - 0.69 9.2 20.2 5.7 6.2 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 CBY36714.1 - 0.71 10.2 9.6 0.15 12.3 2.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 CBY36714.1 - 0.96 9.7 7.1 6.9 6.9 7.1 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 CBY36714.1 - 2.7 8.4 19.9 4.8 7.6 2.7 3.3 1 1 2 3 3 3 0 Lipoprotein leucine-zipper YlqD PF11068.8 CBY36714.1 - 2.7 8.4 24.6 2.9 8.2 15.3 2.0 1 1 1 2 2 2 0 YlqD protein ECM1 PF05782.11 CBY36714.1 - 3.8 6.3 18.8 4.1 6.2 18.8 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF1664 PF07889.12 CBY36714.1 - 5.4 7.1 8.7 9 6.4 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CBY36714.1 - 7.2 5.8 10.7 8.9 5.5 10.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Presenilin PF01080.17 CBY36714.1 - 7.6 5.2 17.9 8.6 5.0 17.9 1.0 1 0 0 1 1 1 0 Presenilin Sec34 PF04136.15 CBY36714.1 - 8.2 6.3 12.2 2.3 8.1 5.0 2.0 1 1 1 2 2 2 0 Sec34-like family Lin-8 PF03353.15 CBY36714.1 - 8.7 5.8 23.2 12 5.3 23.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Innexin PF00876.18 CBY36715.1 - 0.00067 19.0 0.0 0.00074 18.9 0.0 1.1 1 0 0 1 1 1 1 Innexin WW_like PF17890.1 CBY36715.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Lustrin_cystein PF14625.6 CBY36716.1 - 0.53 10.7 4.4 4.7 7.7 0.1 3.0 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Ion_trans PF00520.31 CBY36718.1 - 2.1e-21 76.3 23.0 2.9e-21 75.8 23.0 1.2 1 0 0 1 1 1 1 Ion transport protein ODV-E18 PF10717.9 CBY36718.1 - 0.28 11.1 5.2 0.87 9.5 0.0 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 DUF4446 PF14584.6 CBY36718.1 - 4.1 7.4 12.0 0.15 12.0 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) Lactamase_B PF00753.27 CBY36719.1 - 5.2e-05 23.3 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY36719.1 - 0.0018 17.8 0.2 0.0035 16.9 0.2 1.5 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Phospholip_A2_1 PF00068.19 CBY36721.1 - 6.4e-29 100.7 15.5 6.4e-29 100.7 15.5 2.3 2 1 0 2 2 2 1 Phospholipase A2 Phospholip_A2_2 PF05826.12 CBY36721.1 - 6.6 7.0 23.1 0.55 10.5 6.5 3.1 1 1 1 2 2 2 0 Phospholipase A2 Sulfotransfer_1 PF00685.27 CBY36722.1 - 5.2e-20 72.0 3.6 1.4e-19 70.7 1.0 2.4 1 1 1 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36722.1 - 1.8e-09 38.3 0.0 1.1e-08 35.7 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family DUF2681 PF10883.8 CBY36722.1 - 0.15 12.5 1.5 0.31 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PLAC8 PF04749.17 CBY36724.1 - 1.3e-16 61.4 3.9 1.5e-16 61.2 3.9 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase_Tyr PF07714.17 CBY36726.1 - 1.5e-63 214.5 0.0 3.5e-63 213.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36726.1 - 6.3e-32 111.0 0.3 5e-31 108.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain 4HB_MCP_1 PF12729.7 CBY36726.1 - 0.0097 15.5 0.2 0.045 13.3 0.1 2.1 1 1 1 2 2 2 1 Four helix bundle sensory module for signal transduction DUF2681 PF10883.8 CBY36726.1 - 0.016 15.6 0.4 0.016 15.6 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Fijivirus_P9-2 PF06837.11 CBY36726.1 - 0.082 12.4 0.9 10 5.5 0.1 2.4 2 0 0 2 2 2 0 Fijivirus P9-2 protein VipB PF05943.12 CBY36729.1 - 0.011 14.5 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath zf-LITAF-like PF10601.9 CBY36729.1 - 0.036 14.3 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Peptidase_M14 PF00246.24 CBY36730.1 - 9.5e-09 35.5 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY36730.1 - 8e-05 23.0 0.1 0.00012 22.3 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase activation peptide DUF3007 PF11460.8 CBY36731.1 - 0.087 13.1 0.0 0.091 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) CYYR1 PF10873.8 CBY36733.1 - 4.1 7.8 7.4 0.83 10.1 1.1 2.1 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 Thioredoxin_2 PF13098.6 CBY36734.1 - 0.072 13.6 0.3 0.12 12.9 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY36734.1 - 0.11 12.6 0.1 0.22 11.7 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin VWA PF00092.28 CBY36735.1 - 5.1e-32 111.5 1.5 1.1e-31 110.5 1.5 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY36735.1 - 5.2e-13 49.6 1.9 6.6e-13 49.2 0.4 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain CUB PF00431.20 CBY36735.1 - 1.4e-06 28.6 0.1 1.9e-05 24.9 0.1 2.7 1 1 0 1 1 1 1 CUB domain EB PF01683.18 CBY36735.1 - 0.59 10.5 18.5 3.6 8.0 4.0 2.7 1 1 1 2 2 2 0 EB module Sulfotransfer_1 PF00685.27 CBY36736.1 - 9.1e-07 28.6 0.3 1.4e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36736.1 - 0.043 14.2 0.0 0.32 11.3 0.0 2.2 1 1 0 1 1 1 0 Sulfotransferase family Homeodomain PF00046.29 CBY36737.1 - 1.2e-22 79.5 1.1 2e-22 78.8 1.1 1.4 1 0 0 1 1 1 1 Homeodomain SatD PF16264.5 CBY36737.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 SatD family (SatD) DUF515 PF04415.12 CBY36737.1 - 4.7 5.5 9.0 9.8 4.4 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) adh_short PF00106.25 CBY36738.1 - 4.5e-34 117.6 0.2 6.8e-34 117.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY36738.1 - 1.3e-27 96.9 0.2 1.6e-27 96.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY36738.1 - 1.1e-07 32.0 0.2 4e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CBY36738.1 - 0.00078 19.0 0.0 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CBY36738.1 - 0.0073 16.4 0.4 0.014 15.5 0.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBY36738.1 - 0.024 14.0 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EF-hand_5 PF13202.6 CBY36738.1 - 0.024 14.1 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 EF hand NAD_binding_10 PF13460.6 CBY36738.1 - 0.036 13.9 0.1 0.051 13.5 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 CBY36738.1 - 0.07 13.7 0.1 0.19 12.3 0.0 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CBY36738.1 - 0.077 12.9 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 CBY36738.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair TIG PF01833.24 CBY36738.1 - 0.098 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 IPT/TIG domain EF-hand_6 PF13405.6 CBY36738.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 CBY36738.1 - 0.33 10.8 1.3 0.35 10.7 0.1 1.7 2 0 0 2 2 2 0 EF-hand domain pair Actin PF00022.19 CBY36739.1 - 4.3e-152 506.5 0.0 1.4e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin DUF2985 PF11204.8 CBY36740.1 - 0.052 13.7 0.6 0.09 12.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) FGGY_N PF00370.21 CBY36742.1 - 1.5e-18 67.2 0.0 6.4e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Mito_carr PF00153.27 CBY36744.1 - 3.5e-58 193.5 0.2 1.3e-18 66.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dsrm PF00035.26 CBY36745.1 - 1.2e-35 122.0 24.0 1.3e-10 41.8 0.6 6.9 6 2 0 6 6 6 5 Double-stranded RNA binding motif Staufen_C PF16482.5 CBY36745.1 - 3.4e-21 75.5 1.6 2.3e-19 69.6 0.1 3.8 4 1 0 4 4 4 1 Staufen C-terminal domain DND1_DSRM PF14709.7 CBY36745.1 - 0.0016 18.7 13.1 0.82 10.0 0.2 5.2 5 1 0 5 5 5 3 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 CBY36745.1 - 0.012 15.8 1.2 31 4.8 0.0 5.0 5 1 0 5 5 5 0 Dicer dimerisation domain Peptidase_C107 PF17222.3 CBY36745.1 - 0.21 10.5 0.1 0.35 9.8 0.1 1.2 1 0 0 1 1 1 0 Viral cysteine endopeptidase C107 Phospholip_A2_1 PF00068.19 CBY36747.1 - 2.7e-16 60.0 9.1 3.6e-16 59.6 9.1 1.2 1 0 0 1 1 1 1 Phospholipase A2 Kelch_2 PF07646.15 CBY36748.1 - 0.00015 21.6 0.3 0.95 9.6 0.2 3.1 3 0 0 3 3 3 2 Kelch motif UL45 PF05473.12 CBY36748.1 - 0.048 13.3 0.2 0.087 12.5 0.2 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1517 PF07466.11 CBY36748.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Lectin_C PF00059.21 CBY36748.1 - 0.25 12.1 2.2 24 5.7 0.0 2.7 1 1 1 2 2 2 0 Lectin C-type domain MAS20 PF02064.15 CBY36749.1 - 0.0058 16.7 2.9 0.26 11.4 0.5 2.3 2 0 0 2 2 2 2 MAS20 protein import receptor BAR_3 PF16746.5 CBY36749.1 - 0.051 13.3 1.4 0.059 13.1 1.4 1.2 1 1 0 1 1 1 0 BAR domain of APPL family GAGA_bind PF06217.12 CBY36749.1 - 0.067 13.5 3.0 0.078 13.3 3.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GEN1_C PF18380.1 CBY36749.1 - 0.11 13.3 6.0 0.2 12.6 6.0 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Ndc1_Nup PF09531.10 CBY36749.1 - 0.95 8.1 2.3 1.2 7.7 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Snf7 PF03357.21 CBY36750.1 - 1.7e-41 141.7 22.6 2.6e-41 141.1 22.6 1.2 1 0 0 1 1 1 1 Snf7 UCH PF00443.29 CBY36750.1 - 0.11 12.0 4.1 0.14 11.6 4.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HlyD_2 PF12700.7 CBY36750.1 - 0.47 9.1 12.2 0.68 8.6 12.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein GrpE PF01025.19 CBY36750.1 - 0.66 9.6 12.1 1.1 8.9 12.1 1.4 1 0 0 1 1 1 0 GrpE RSRP PF17069.5 CBY36750.1 - 1.4 8.4 7.9 2.2 7.8 7.8 1.4 1 1 0 1 1 1 0 Arginine/Serine-Rich protein 1 DnaJ-X PF14308.6 CBY36750.1 - 1.9 7.9 19.7 0.28 10.6 15.8 1.6 1 1 0 1 1 1 0 X-domain of DnaJ-containing Vinculin PF01044.19 CBY36752.1 - 8.4e-217 722.7 38.4 3.1e-122 409.7 15.0 2.0 2 0 0 2 2 2 2 Vinculin family TFX_C PF14601.6 CBY36752.1 - 0.0043 17.0 0.7 0.021 14.8 0.1 2.4 3 0 0 3 3 3 1 DNA_binding protein, TFX, C-term DUF4342 PF14242.6 CBY36752.1 - 0.034 14.1 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Rotamase PF00639.21 CBY36752.1 - 0.33 11.9 0.1 0.33 11.9 0.1 5.5 6 0 0 6 6 6 0 PPIC-type PPIASE domain T2SSF PF00482.23 CBY36752.1 - 2.9 7.9 5.7 11 6.0 0.0 4.4 5 1 0 5 5 5 0 Type II secretion system (T2SS), protein F Hormone_recep PF00104.30 CBY36753.1 - 1.8e-14 53.8 2.3 5e-14 52.4 2.3 1.7 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MIEAP PF16026.5 CBY36753.1 - 0.063 13.5 0.7 0.22 11.7 0.1 2.2 1 1 2 3 3 3 0 Mitochondria-eating protein zf-C4 PF00105.18 CBY36754.1 - 1.9e-09 37.8 4.1 2e-09 37.8 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) CAP_assoc_N PF14504.6 CBY36754.1 - 0.031 14.0 0.5 0.051 13.3 0.5 1.3 1 0 0 1 1 1 0 CAP-associated N-terminal DUF3452 PF11934.8 CBY36754.1 - 0.061 12.9 0.3 0.079 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Stc1 PF12898.7 CBY36754.1 - 0.1 13.2 6.4 0.042 14.4 4.0 1.6 1 1 0 1 1 1 0 Stc1 domain Flu_M1_C PF08289.11 CBY36756.1 - 0.058 13.6 0.9 0.12 12.6 0.9 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF948 PF06103.11 CBY36756.1 - 0.49 10.7 3.6 4.2 7.7 0.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CBY36756.1 - 2.5 8.1 8.2 0.89 9.6 2.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 CBY36756.1 - 5.9 6.9 16.9 0.6 10.1 1.1 3.2 2 1 2 4 4 4 0 Prefoldin subunit PLC-beta_C PF08703.10 CBY36756.1 - 5.9 6.8 22.6 0.17 11.8 15.1 2.2 2 1 0 2 2 2 0 PLC-beta C terminal YacG PF03884.14 CBY36757.1 - 0.02 14.6 0.9 0.022 14.5 0.9 1.0 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG MFS_1 PF07690.16 CBY36759.1 - 3.9e-13 49.1 2.2 4.6e-13 48.8 2.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY36759.1 - 0.00084 18.7 0.9 0.0012 18.2 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 CBY36759.1 - 0.0092 14.7 0.3 0.013 14.2 0.2 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like UL20 PF17582.2 CBY36759.1 - 0.033 13.5 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL20 MscL PF01741.18 CBY36759.1 - 0.053 13.8 0.1 0.09 13.1 0.1 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL 7TMR-DISM_7TM PF07695.11 CBY36759.1 - 0.31 10.9 9.7 6.5 6.6 9.7 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling Gram_pos_anchor PF00746.21 CBY36759.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF202 PF02656.15 CBY36759.1 - 1.1 9.8 5.0 5.3 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.25 CBY36761.1 - 3.8e-09 36.3 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36761.1 - 2.2e-07 30.4 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PADR1 PF08063.12 CBY36761.1 - 0.058 13.2 0.3 12 5.8 0.0 3.6 3 0 0 3 3 3 0 PADR1 (NUC008) domain GMC_oxred_C PF05199.13 CBY36762.1 - 2.7e-15 57.2 0.6 3.4e-15 56.8 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Pkinase PF00069.25 CBY36763.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36763.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Shisa PF13908.6 CBY36764.1 - 8.2 6.6 9.4 0.23 11.7 1.3 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Sulfotransfer_2 PF03567.14 CBY36765.1 - 0.00029 20.8 0.8 0.00045 20.2 0.8 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF3865 PF12981.7 CBY36765.1 - 0.12 12.2 1.2 0.14 12.0 0.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) EF-hand_6 PF13405.6 CBY36766.1 - 1.8e-24 83.5 1.8 5.2e-06 26.0 0.2 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY36766.1 - 3.8e-24 84.9 3.1 4.8e-16 59.0 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY36766.1 - 9.4e-24 81.2 9.2 2.7e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 CBY36766.1 - 8e-18 63.1 11.1 0.0001 21.6 0.8 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 CBY36766.1 - 1.5e-14 53.5 6.5 8e-06 25.6 0.3 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY36766.1 - 9.7e-07 28.7 1.0 0.44 10.5 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY36766.1 - 0.0002 21.6 0.4 0.34 11.2 0.0 3.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_3 PF09069.11 CBY36766.1 - 0.0028 18.0 0.0 0.014 15.8 0.0 2.0 2 1 0 2 2 2 1 EF-hand EF-hand_9 PF14658.6 CBY36766.1 - 0.0046 17.2 0.0 0.082 13.2 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain Histone PF00125.24 CBY36767.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36767.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY36767.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY36767.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY36767.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY36768.1 - 1.9e-20 72.3 1.3 4.1e-20 71.2 1.3 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY36768.1 - 4.5e-16 59.4 0.0 5.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY36768.1 - 3.9e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PH_RBD PF12068.8 CBY36769.1 - 0.0019 17.7 0.0 0.039 13.4 0.0 2.0 1 1 0 2 2 2 2 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 CBY36770.1 - 1.1e-40 139.7 0.1 1.7e-40 139.0 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.10 CBY36770.1 - 0.041 13.6 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 UTP15 C terminal NYD-SP28_assoc PF14775.6 CBY36770.1 - 0.21 11.7 1.0 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain CENP-T_C PF15511.6 CBY36771.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY36771.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY36771.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY36771.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY36771.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY36771.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY36771.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY36771.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GTP_EFTU PF00009.27 CBY36772.1 - 1.5e-20 73.5 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY36772.1 - 0.00029 21.1 1.5 0.0035 17.6 1.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 CBY36772.1 - 0.0029 17.3 0.6 1.2 8.9 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CBY36772.1 - 0.0041 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBY36772.1 - 0.028 14.7 0.3 12 6.2 0.1 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CBY36772.1 - 0.029 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MORN_2 PF07661.13 CBY36774.1 - 0.078 13.2 0.1 64 4.3 0.1 3.6 3 0 0 3 3 3 0 MORN repeat variant APG6 PF04111.12 CBY36775.1 - 3.1e-45 154.3 0.4 9.9e-45 152.7 0.0 1.8 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 CBY36775.1 - 2.9e-07 31.1 21.8 4.7e-07 30.4 21.8 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region LCD1 PF09798.9 CBY36775.1 - 0.00021 20.0 2.4 0.00024 19.8 2.4 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein V_ATPase_I PF01496.19 CBY36775.1 - 0.0034 15.4 4.5 0.0042 15.1 4.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HALZ PF02183.18 CBY36775.1 - 0.011 15.9 9.9 3.6 7.9 0.7 3.9 4 0 0 4 4 3 0 Homeobox associated leucine zipper MscS_porin PF12795.7 CBY36775.1 - 0.015 14.8 11.3 0.022 14.3 11.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Atg14 PF10186.9 CBY36775.1 - 0.066 12.3 5.0 0.12 11.5 5.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 CBY36775.1 - 0.093 13.1 3.2 11 6.5 0.1 3.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper AKNA PF12443.8 CBY36775.1 - 0.12 13.0 0.4 0.12 13.0 0.4 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor MPS2 PF17060.5 CBY36775.1 - 0.2 10.9 8.2 0.27 10.4 8.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Exonuc_VII_L PF02601.15 CBY36775.1 - 0.21 11.1 5.5 0.29 10.7 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 CBY36775.1 - 0.28 11.6 16.3 0.42 11.0 15.0 1.8 1 1 1 2 2 2 0 Fez1 YABBY PF04690.13 CBY36775.1 - 0.44 11.1 3.6 2.4 8.7 3.6 2.2 1 1 0 1 1 1 0 YABBY protein Polbeta PF18765.1 CBY36775.1 - 0.63 10.2 4.4 0.41 10.8 0.4 2.5 1 1 3 4 4 4 0 Polymerase beta, Nucleotidyltransferase FapA PF03961.13 CBY36775.1 - 0.84 8.2 8.5 1.2 7.7 8.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fzo_mitofusin PF04799.13 CBY36775.1 - 1.1 8.7 8.6 0.31 10.6 4.2 2.1 1 1 1 2 2 2 0 fzo-like conserved region CpXC PF14353.6 CBY36775.1 - 1.5 8.9 5.4 3.7 7.6 5.4 1.6 1 1 0 1 1 1 0 CpXC protein Seryl_tRNA_N PF02403.22 CBY36775.1 - 2.8 8.2 15.1 1 9.6 12.1 1.9 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 CBY36775.1 - 3.3 6.5 20.1 11 4.8 20.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ZapB PF06005.12 CBY36775.1 - 3.7 8.1 20.1 1.3 9.5 5.2 3.0 1 1 1 2 2 2 0 Cell division protein ZapB zf-C4H2 PF10146.9 CBY36775.1 - 4.5 7.5 10.6 1.5 9.1 7.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.12 CBY36775.1 - 5.2 7.1 6.6 18 5.4 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 CBY36775.1 - 8.3 6.5 10.1 19 5.3 10.1 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SH3BGR PF04908.15 CBY36776.1 - 4.9e-06 26.6 0.7 4.9e-06 26.6 0.7 1.8 2 1 0 2 2 2 1 SH3-binding, glutamic acid-rich protein FAM184 PF15665.5 CBY36777.1 - 0.0004 20.2 11.3 0.00069 19.5 11.3 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B YabA PF06156.13 CBY36777.1 - 0.0093 16.6 2.9 0.0093 16.6 2.9 2.4 1 1 1 2 2 2 1 Initiation control protein YabA MtrF PF09472.10 CBY36777.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syntaxin-6_N PF09177.11 CBY36777.1 - 0.21 12.2 9.4 0.66 10.6 8.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 CBY36777.1 - 0.21 11.6 16.6 0.12 12.4 11.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ALMT PF11744.8 CBY36777.1 - 1 8.2 6.8 1.4 7.7 6.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3496 PF12001.8 CBY36777.1 - 1 9.7 11.3 11 6.5 7.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) DUF4407 PF14362.6 CBY36777.1 - 1.7 7.9 12.3 2 7.7 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VSG_B PF13206.6 CBY36777.1 - 2 7.6 11.7 2.3 7.4 11.7 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4559 PF15112.6 CBY36777.1 - 3.6 7.2 14.9 0.55 9.8 11.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) V_ATPase_I PF01496.19 CBY36777.1 - 9.4 4.0 12.4 11 3.7 12.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HOOK PF05622.12 CBY36779.1 - 0.0018 16.5 25.7 0.0018 16.5 25.7 5.5 1 1 4 5 5 5 1 HOOK protein KASH_CCD PF14662.6 CBY36779.1 - 0.0051 16.7 24.0 0.0051 16.7 24.0 8.8 2 2 5 8 8 8 2 Coiled-coil region of CCDC155 or KASH DUF4207 PF13904.6 CBY36780.1 - 5.5e-08 32.8 57.0 5.5e-08 32.8 57.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) TP53IP5 PF15331.6 CBY36780.1 - 0.18 12.0 29.5 0.22 11.6 29.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CAF-1_p150 PF11600.8 CBY36780.1 - 1.3 8.6 55.2 2 8.1 55.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.11 CBY36780.1 - 1.7 8.7 34.5 2.1 8.4 34.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NPAT_C PF15712.5 CBY36780.1 - 1.8 7.1 29.2 2 7.0 29.2 1.0 1 0 0 1 1 1 0 NPAT C terminus hDGE_amylase PF14701.6 CBY36780.1 - 8.2 5.4 17.3 10 5.1 17.3 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain TRAM_LAG1_CLN8 PF03798.16 CBY36782.1 - 8.2e-21 74.7 17.4 1.3e-20 74.0 17.4 1.3 1 0 0 1 1 1 1 TLC domain Sulfotransfer_2 PF03567.14 CBY36784.1 - 0.0021 18.0 0.3 0.0021 18.0 0.3 1.5 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY36785.1 - 8.4e-11 41.8 2.8 1.7e-08 34.3 2.8 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36785.1 - 1.6e-06 28.7 0.4 0.00023 21.6 0.1 2.2 1 1 0 2 2 2 2 Sulfotransferase family Trypsin PF00089.26 CBY36786.1 - 1.3e-05 25.1 0.0 0.0002 21.2 0.1 2.0 1 1 1 2 2 2 2 Trypsin MAR_sialic_bdg PF10564.9 CBY36787.1 - 2.9e-164 533.6 66.0 3.2e-19 68.8 0.2 11.6 12 0 0 12 12 12 10 Sialic-acid binding micronemal adhesive repeat CCDC23 PF15674.5 CBY36787.1 - 3.6e-05 23.7 8.3 21 5.2 0.3 7.9 9 0 0 9 9 9 1 Coiled-coil domain-containing protein 23 EF-hand_9 PF14658.6 CBY36787.1 - 0.031 14.6 0.0 11 6.5 0.0 4.3 5 0 0 5 5 5 0 EF-hand domain Frigida PF07899.11 CBY36787.1 - 0.094 12.0 3.6 21 4.2 0.0 5.1 7 0 0 7 7 7 0 Frigida-like protein DDHD PF02862.17 CBY36787.1 - 0.26 11.4 5.9 1.1 9.3 3.2 2.3 2 0 0 2 2 2 0 DDHD domain Tim54 PF11711.8 CBY36787.1 - 4.2 6.1 9.8 2 7.1 2.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 APC_u15 PF16636.5 CBY36788.1 - 0.078 13.4 3.0 0.27 11.7 2.0 2.3 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 CD20 PF04103.15 CBY36788.1 - 0.086 12.9 0.2 0.086 12.9 0.2 2.0 2 0 0 2 2 2 0 CD20-like family DUF308 PF03729.13 CBY36788.1 - 0.12 12.7 5.0 0.19 12.1 5.0 1.3 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) COPI_assoc PF08507.10 CBY36788.1 - 0.26 11.4 2.5 7.6 6.6 2.5 2.2 1 1 0 1 1 1 0 COPI associated protein Trypsin PF00089.26 CBY36789.1 - 3.5e-42 144.7 0.1 5.6e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY36789.1 - 0.00093 20.1 0.0 0.002 19.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain TSP_1 PF00090.19 CBY36789.1 - 0.0012 19.0 2.7 0.0012 19.0 2.7 3.4 4 0 0 4 4 4 1 Thrombospondin type 1 domain Trefoil PF00088.18 CBY36789.1 - 0.013 15.4 8.2 0.013 15.4 8.2 3.6 3 0 0 3 3 3 0 Trefoil (P-type) domain Ig_3 PF13927.6 CBY36790.1 - 1.7e-08 35.0 7.5 0.016 15.8 0.3 6.3 5 2 0 5 5 5 2 Immunoglobulin domain Ig_2 PF13895.6 CBY36790.1 - 1.1e-06 28.8 1.8 2.1 8.7 0.1 4.8 3 1 1 4 4 4 2 Immunoglobulin domain I-set PF07679.16 CBY36790.1 - 2.6e-05 24.2 0.8 11 6.2 0.0 6.0 6 1 0 7 7 7 1 Immunoglobulin I-set domain C1-set PF07654.15 CBY36790.1 - 0.00028 21.2 0.5 4.5 7.7 0.0 3.7 3 0 0 3 3 3 1 Immunoglobulin C1-set domain ig PF00047.25 CBY36790.1 - 0.00028 21.0 2.7 14 5.9 0.0 5.5 4 1 0 4 4 4 1 Immunoglobulin domain Ig_4 PF16680.5 CBY36790.1 - 0.044 14.1 0.3 3.9 7.8 0.0 3.5 4 0 0 4 4 4 0 T-cell surface glycoprotein CD3 delta chain PK PF00224.21 CBY36790.1 - 0.06 12.2 0.1 0.097 11.5 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF4073 PF13285.6 CBY36790.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Zona_pellucida PF00100.23 CBY36791.1 - 1.9e-19 70.5 2.7 2.2e-19 70.3 2.7 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain DUF5627 PF18620.1 CBY36791.1 - 0.021 14.7 3.0 0.61 10.0 0.2 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5627) Band_7 PF01145.25 CBY36793.1 - 6.2e-33 114.3 0.3 7.7e-33 114.0 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY36793.1 - 0.0056 16.4 0.1 0.0079 15.9 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family adh_short PF00106.25 CBY36794.1 - 7.2e-49 165.9 1.1 9.7e-49 165.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY36794.1 - 1.3e-47 162.4 0.3 1.6e-47 162.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY36794.1 - 6.6e-13 49.0 0.4 9.4e-13 48.5 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY36794.1 - 0.048 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF218 PF02698.17 CBY36794.1 - 0.13 12.3 0.1 0.58 10.2 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain DUF1011 PF06237.12 CBY36795.1 - 2.1e-28 98.6 9.1 2.1e-28 98.6 9.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1011) Phospholip_A2_1 PF00068.19 CBY36796.1 - 5.1e-15 55.9 6.4 5.1e-15 55.9 6.4 2.2 2 1 0 2 2 2 1 Phospholipase A2 LLC1 PF14945.6 CBY36797.1 - 4.5e-32 111.1 2.5 6e-32 110.7 2.5 1.2 1 0 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Glyco_hydro_1 PF00232.18 CBY36798.1 - 1.8e-140 468.4 12.1 2.1e-140 468.2 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 fn3 PF00041.21 CBY36801.1 - 4.1e-42 142.4 0.2 4.9e-12 46.0 0.0 4.3 4 0 0 4 4 4 4 Fibronectin type III domain I-set PF07679.16 CBY36801.1 - 1.8e-13 50.4 0.1 9e-12 44.9 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY36801.1 - 8.9e-07 29.4 0.0 2.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain fn3_2 PF16893.5 CBY36801.1 - 0.00043 20.4 0.0 0.0047 17.0 0.0 2.4 3 0 0 3 3 3 1 Fibronectin type III domain ig PF00047.25 CBY36801.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY36801.1 - 0.013 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain RRM_1 PF00076.22 CBY36802.1 - 1e-33 114.9 0.3 1.4e-12 47.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DND1_DSRM PF14709.7 CBY36802.1 - 8.9e-20 70.7 0.1 2.4e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_7 PF16367.5 CBY36802.1 - 4e-05 23.6 0.0 0.45 10.7 0.0 3.1 2 0 0 2 2 2 2 RNA recognition motif WD40_3 PF15911.5 CBY36803.1 - 2.6e-09 36.9 0.0 9.5e-09 35.1 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY36803.1 - 7.8e-07 29.3 1.1 0.44 10.9 0.2 5.7 3 2 3 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CBY36803.1 - 1.2e-06 28.5 1.7 1.5 8.7 0.1 5.0 4 0 0 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 CBY36803.1 - 3.9e-06 26.2 7.7 0.032 13.3 0.3 5.6 5 1 2 7 7 7 2 Coatomer WD associated region TPR_14 PF13428.6 CBY36803.1 - 0.00019 22.0 3.9 1.1 10.2 0.1 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY36803.1 - 0.00089 19.7 6.5 3.1 8.4 0.2 5.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36803.1 - 0.0012 18.8 18.6 9.4 6.6 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36803.1 - 0.0014 18.8 6.4 4.1 7.7 0.0 5.8 6 1 1 7 7 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Rad50_zn_hook PF04423.14 CBY36803.1 - 0.24 11.3 8.4 0.18 11.6 0.3 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif TPR_7 PF13176.6 CBY36803.1 - 0.32 11.1 11.9 45 4.4 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36803.1 - 0.34 10.6 5.7 19 5.0 0.1 4.5 4 0 0 4 4 4 0 TPR repeat WD40 PF00400.32 CBY36803.1 - 0.34 11.9 6.8 1.7e+02 3.3 0.1 6.1 5 1 1 6 6 6 0 WD domain, G-beta repeat TPR_8 PF13181.6 CBY36803.1 - 0.35 11.2 11.4 2.5 8.5 0.1 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36803.1 - 0.56 10.5 8.5 42 4.5 0.3 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY36803.1 - 0.79 9.7 13.5 21 5.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 CBY36803.1 - 3.8 7.0 5.2 6.2 6.4 1.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CBY36803.1 - 8.6 6.5 11.4 4.5 7.4 1.6 2.5 1 1 1 2 2 2 0 Double zinc ribbon CHD5 PF04420.14 CBY36804.1 - 1.5e-12 47.7 1.0 2.7e-12 46.8 1.0 1.4 1 1 0 1 1 1 1 CHD5-like protein dNK PF01712.19 CBY36805.1 - 3.8e-62 209.8 0.0 4.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 CBY36805.1 - 1.9e-05 25.2 1.1 0.00046 20.7 0.1 3.0 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CBY36805.1 - 0.0035 17.1 1.2 0.029 14.1 0.1 2.6 1 1 1 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 CBY36805.1 - 0.037 14.2 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Spore_IV_A PF09547.10 CBY36805.1 - 0.063 12.2 0.4 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) DUF2362 PF10154.9 CBY36807.1 - 0.0083 15.1 0.3 0.0095 14.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DUF3040 PF11239.8 CBY36807.1 - 0.21 11.9 0.1 0.3 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1299 PF06975.11 CBY36809.1 - 8 6.6 9.6 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1299) HLH PF00010.26 CBY36810.1 - 1.1e-15 57.3 3.0 2.2e-15 56.3 3.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CBY36810.1 - 0.59 10.1 7.2 0.66 9.9 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CBY36811.1 - 2.8e-17 63.0 1.2 5.1e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36811.1 - 3.3e-09 36.4 0.0 6.5e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5001 PF16392.5 CBY36811.1 - 0.056 13.4 3.4 0.12 12.3 0.2 2.9 2 1 1 3 3 3 0 Ig-like domain Glyco_transf_7C PF02709.14 CBY36812.1 - 4.7e-15 55.0 0.1 7.4e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TOBE PF03459.17 CBY36812.1 - 0.16 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 TOBE domain ATP-gua_Ptrans PF00217.19 CBY36813.1 - 1.7e-60 204.1 0.0 2.3e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY36813.1 - 8.7e-24 83.7 0.0 1.4e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Topoisom_bac PF01131.20 CBY36814.1 - 2.2e-103 346.4 0.0 2.9e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CBY36814.1 - 1.6e-22 79.3 19.2 2.6e-14 53.0 2.5 3.3 4 0 0 4 4 4 2 GRF zinc finger Toprim PF01751.22 CBY36814.1 - 4.1e-17 62.3 0.0 8.5e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 CBY36814.1 - 9.3e-05 22.1 6.3 9.3e-05 22.1 6.3 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CBY36814.1 - 0.26 11.4 4.9 1.2 9.4 4.9 2.3 1 0 0 1 1 1 0 Zinc knuckle NAP PF00956.18 CBY36815.1 - 2.5e-14 53.1 4.9 3.7e-14 52.6 4.9 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) AAR2 PF05282.11 CBY36815.1 - 0.031 13.7 0.7 0.042 13.3 0.4 1.4 1 1 0 1 1 1 0 AAR2 protein RabGAP-TBC PF00566.18 CBY36816.1 - 0.0042 16.8 0.1 0.0042 16.8 0.1 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 CBY36816.1 - 0.033 14.2 22.2 0.03 14.4 15.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 CBY36816.1 - 0.15 12.4 8.5 2.8 8.4 0.3 3.9 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Sfi1_C PF10638.9 CBY36816.1 - 0.26 12.1 7.0 0.21 12.4 0.7 2.5 2 0 0 2 2 2 0 Spindle body associated protein C-terminus KfrA_N PF11740.8 CBY36816.1 - 2 9.1 13.2 0.57 10.9 0.7 3.3 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF1664 PF07889.12 CBY36816.1 - 2.1 8.4 8.0 1.3 9.0 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CBY36816.1 - 2.7 8.1 31.1 0.44 10.6 14.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 CBY36816.1 - 5.3 7.7 12.7 3.8 8.2 0.2 3.8 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.6 CBY36816.1 - 7.7 6.9 32.5 6.9 7.1 22.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Dsh_C PF12316.8 CBY36817.1 - 0.012 16.0 17.6 0.012 16.0 17.6 3.3 1 1 2 3 3 3 0 Segment polarity protein dishevelled (Dsh) C terminal TFIIA PF03153.13 CBY36817.1 - 9.9 6.0 39.0 15 5.4 39.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMMR_C PF15908.5 CBY36818.1 - 6.4e-06 26.5 11.5 6.4e-06 26.5 11.5 6.6 1 1 6 7 7 7 1 Hyaluronan mediated motility receptor C-terminal SHIPPO-rpt PF07004.12 CBY36818.1 - 0.22 12.5 0.1 0.53 11.3 0.1 1.6 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat CHGN PF05679.16 CBY36819.1 - 1.2e-40 139.8 11.5 3.3e-21 75.7 2.8 3.9 1 1 1 3 3 3 3 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY36819.1 - 2.2e-07 30.5 1.1 4e-07 29.6 1.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase IFT20 PF14931.6 CBY36819.1 - 0.11 12.7 1.6 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF641 PF04859.12 CBY36819.1 - 0.58 10.5 8.6 28 5.1 0.0 4.0 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Spore_III_AB PF09548.10 CBY36820.1 - 0.25 11.4 3.2 0.11 12.6 0.5 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Mt_ATP-synt_B PF05405.14 CBY36820.1 - 0.51 9.9 6.3 1 9.0 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Kinesin PF00225.23 CBY36821.1 - 1.2e-112 376.2 0.1 1.7e-112 375.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CBY36821.1 - 1.6e-42 145.7 7.6 4.9e-33 114.8 0.2 3.2 2 1 1 3 3 3 2 Kinesin-associated DUF3694 PF12473.8 CBY36821.1 - 3.3e-31 109.0 0.0 9.3e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 CBY36821.1 - 2.8e-23 82.5 0.1 6.8e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CBY36821.1 - 5.5e-10 39.7 0.0 1.9e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.26 CBY36821.1 - 0.00014 22.1 0.0 0.00081 19.7 0.0 2.4 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 CBY36821.1 - 0.00027 21.3 0.1 0.0071 16.7 0.1 2.9 1 1 0 1 1 1 1 Kinesin protein 1B Yop-YscD_cpl PF16697.5 CBY36821.1 - 0.0065 16.8 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PXPV PF12778.7 CBY36822.1 - 0.18 11.7 13.4 0.32 10.9 13.4 1.4 1 0 0 1 1 1 0 PXPV repeat (3 copies) FAD_binding_7 PF03441.14 CBY36823.1 - 1.9e-57 194.1 3.3 3.4e-57 193.2 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBY36823.1 - 4.7e-40 137.3 0.0 7.9e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase AF-4 PF05110.13 CBY36825.1 - 0.033 12.3 7.6 0.037 12.1 7.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CTNNB1_binding PF08347.11 CBY36825.1 - 0.079 13.1 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CDC45 PF02724.14 CBY36825.1 - 0.11 10.8 6.7 0.11 10.8 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.22 CBY36826.1 - 1.1e-44 152.9 3.8 1.6e-44 152.4 3.8 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CBY36826.1 - 5.9e-20 71.1 0.1 1.1e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Kelch_6 PF13964.6 CBY36827.1 - 1.4e-06 28.4 1.9 1.6 9.1 0.0 3.8 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBY36827.1 - 0.18 11.9 3.0 14 5.8 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY36827.1 - 0.23 11.8 4.1 2.8 8.3 0.3 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Kazal_2 PF07648.15 CBY36828.1 - 5.1e-05 23.3 0.2 6.7e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY36828.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain G8 PF10162.9 CBY36829.1 - 2.3e-51 173.0 0.0 2.8e-26 92.0 0.0 2.9 2 0 0 2 2 2 2 G8 domain TIG PF01833.24 CBY36829.1 - 3.8e-35 119.8 41.9 1.5e-14 53.8 0.2 9.6 10 0 0 10 10 10 5 IPT/TIG domain EGF_3 PF12947.7 CBY36829.1 - 2.1e-16 59.8 42.8 4.3e-09 36.4 12.4 4.3 3 0 0 3 3 3 3 EGF domain EGF_CA PF07645.15 CBY36829.1 - 2e-13 50.3 56.3 4.7e-06 26.7 11.4 4.7 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CBY36829.1 - 2.7e-08 33.6 33.1 8e-05 22.5 2.3 5.5 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF PF00008.27 CBY36829.1 - 2.7e-07 30.8 31.5 0.0047 17.2 7.3 4.4 3 0 0 3 3 3 3 EGF-like domain Beta_helix PF13229.6 CBY36829.1 - 2.7e-07 30.5 16.7 0.0028 17.5 3.6 4.6 4 0 0 4 4 4 2 Right handed beta helix region NosD PF05048.13 CBY36829.1 - 3.9e-05 23.0 0.6 3.9e-05 23.0 0.6 3.1 3 0 0 3 3 3 1 Periplasmic copper-binding protein (NosD) hEGF PF12661.7 CBY36829.1 - 0.00094 19.7 26.7 0.14 12.8 6.1 4.6 3 0 0 3 3 3 2 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY36829.1 - 0.0021 18.3 34.3 0.092 13.0 9.0 4.1 2 1 1 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY36829.1 - 0.5 10.5 34.8 0.034 14.2 6.8 3.9 3 0 0 3 3 3 0 MSP1 EGF domain 1 ADK PF00406.22 CBY36831.1 - 1.1e-40 139.1 0.0 1.5e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY36831.1 - 1.1e-34 119.7 0.0 1.8e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY36831.1 - 2.2e-09 38.0 0.1 4.2e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY36831.1 - 1.2e-06 28.8 0.0 5.5e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBY36831.1 - 0.00022 21.0 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 CBY36831.1 - 0.00044 20.2 0.2 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CBY36831.1 - 0.00067 19.0 0.1 0.0031 16.8 0.1 2.1 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase1 PF18748.1 CBY36831.1 - 0.015 14.8 0.0 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 TetR_C_24 PF17932.1 CBY36831.1 - 0.064 13.5 0.3 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glycos_trans_3N PF02885.17 CBY36831.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain tRNA-synt_1b PF00579.25 CBY36833.1 - 4.7e-68 229.7 0.0 6.7e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 CBY36833.1 - 1.1e-30 105.6 0.3 2.5e-30 104.4 0.3 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 CBY36833.1 - 3.3e-07 30.4 0.0 1.2e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY36833.1 - 0.025 14.6 0.1 0.07 13.2 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EnY2 PF10163.9 CBY36834.1 - 6.9e-27 93.6 0.2 7.8e-27 93.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Asparaginase_2 PF01112.18 CBY36835.1 - 1.4e-31 109.7 0.1 2e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 Asparaginase Glyco_hydro_36 PF17167.4 CBY36835.1 - 0.045 12.4 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain PIN_12 PF16289.5 CBY36835.1 - 0.094 13.2 1.2 0.38 11.2 0.0 2.0 1 1 0 2 2 2 0 PIN domain Plexin_cytopl PF08337.12 CBY36836.1 - 5.8e-159 530.3 5.8 8.6e-159 529.7 5.8 1.3 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain PSI PF01437.25 CBY36836.1 - 4.4e-10 39.9 41.6 2.1e-07 31.4 12.3 4.3 3 0 0 3 3 3 3 Plexin repeat TIG PF01833.24 CBY36836.1 - 2.3e-08 34.0 0.9 0.0094 16.0 0.0 3.1 2 0 0 2 2 2 2 IPT/TIG domain Cornichon PF03311.14 CBY36837.1 - 1.3e-12 48.1 2.1 1.6e-12 47.9 2.1 1.2 1 0 0 1 1 1 1 Cornichon protein zf-CCCH_4 PF18044.1 CBY36839.1 - 1.4e-06 27.9 5.6 2.1e-06 27.4 5.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY36839.1 - 1.7e-06 27.9 7.8 3.4e-06 26.9 7.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBY36839.1 - 4.7e-05 23.2 3.7 7.4e-05 22.5 3.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CCDC85 PF10226.9 CBY36839.1 - 0.002 17.8 0.4 0.0027 17.4 0.4 1.2 1 0 0 1 1 1 1 CCDC85 family PLU-1 PF08429.11 CBY36839.1 - 0.0056 15.9 1.1 0.0056 15.9 1.1 1.1 1 0 0 1 1 1 1 PLU-1-like protein Herpes_UL6 PF01763.16 CBY36839.1 - 0.008 14.7 0.2 0.008 14.7 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like zf-CCCH_2 PF14608.6 CBY36839.1 - 0.025 15.0 6.0 0.047 14.2 6.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3213 PF11491.8 CBY36839.1 - 0.035 14.3 0.2 9.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) zf-RING_2 PF13639.6 CBY36840.1 - 5.6e-06 26.6 10.6 5.6e-06 26.6 10.6 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBY36840.1 - 5.5e-05 23.0 10.4 0.00016 21.5 10.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY36840.1 - 8.2e-05 22.4 11.3 0.00019 21.2 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 CBY36840.1 - 0.00013 21.7 4.5 0.00013 21.7 4.5 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY36840.1 - 0.00034 20.6 5.5 0.001 19.0 5.5 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBY36840.1 - 0.00052 19.9 2.4 0.0015 18.4 2.4 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 CBY36840.1 - 0.0009 19.1 11.5 0.0019 18.0 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY36840.1 - 0.0011 18.9 8.7 0.0011 18.9 8.7 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY36840.1 - 0.0015 18.5 12.3 0.0015 18.5 12.3 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Csm1_N PF18504.1 CBY36840.1 - 0.0059 16.9 1.4 0.011 16.1 1.4 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain CCDC24 PF15669.5 CBY36840.1 - 0.0077 16.1 0.2 0.051 13.4 0.1 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family SWI-SNF_Ssr4 PF08549.10 CBY36840.1 - 0.018 13.7 0.5 0.018 13.7 0.5 1.6 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF659 PF04937.15 CBY36840.1 - 0.021 14.7 0.2 0.031 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) MAD PF05557.13 CBY36840.1 - 0.048 12.0 0.3 0.066 11.6 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TMF_DNA_bd PF12329.8 CBY36840.1 - 0.051 13.6 3.6 0.082 12.9 3.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2443 PF10398.9 CBY36840.1 - 0.057 13.5 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Geminin PF07412.12 CBY36840.1 - 0.074 12.8 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Geminin DUF641 PF04859.12 CBY36840.1 - 0.1 12.9 0.3 0.16 12.3 0.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 CBY36840.1 - 0.11 12.3 0.5 0.21 11.4 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-UDP PF14569.6 CBY36840.1 - 1.3 9.2 9.7 4.5 7.5 9.4 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 CBY36840.1 - 1.8 8.4 6.9 1.1 9.1 4.7 1.8 1 1 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 CBY36842.1 - 2.2e-11 43.6 0.0 5.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36842.1 - 3.1e-05 23.4 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pacs-1 PF10254.9 CBY36842.1 - 0.06 12.3 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Lectin_C PF00059.21 CBY36843.1 - 5.3e-16 59.3 3.1 1.3e-15 58.0 3.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Somatomedin_B PF01033.17 CBY36843.1 - 0.00023 21.5 14.6 0.00023 21.5 14.6 2.7 2 0 0 2 2 2 1 Somatomedin B domain DUF2236 PF09995.9 CBY36844.1 - 1e-14 55.3 0.0 1.3e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lipase_3 PF01764.25 CBY36846.1 - 5.3e-19 68.5 0.0 1.4e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY36846.1 - 0.019 15.6 0.0 0.026 15.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CBY36846.1 - 0.031 13.8 0.0 0.076 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CBY36846.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein IRF PF00605.17 CBY36846.1 - 0.067 13.5 3.7 0.13 12.6 0.2 2.3 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Abhydrolase_5 PF12695.7 CBY36846.1 - 0.089 12.6 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family cNMP_binding PF00027.29 CBY36847.1 - 5.5e-11 42.4 0.0 9.9e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_N PF08412.10 CBY36847.1 - 0.089 12.4 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Ion transport protein N-terminal CHGN PF05679.16 CBY36850.1 - 1.5e-09 37.2 2.2 3.3e-09 36.1 1.1 2.0 1 1 1 2 2 2 1 Chondroitin N-acetylgalactosaminyltransferase NYAP_N PF15439.6 CBY36850.1 - 0.071 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter FapA PF03961.13 CBY36850.1 - 0.089 11.4 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 CBY36851.1 - 7.6e-16 58.3 0.2 1.2e-15 57.6 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36851.1 - 7.1e-08 32.0 0.0 9.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF494 PF04361.13 CBY36851.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) APH PF01636.23 CBY36851.1 - 0.22 11.4 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lectin_C PF00059.21 CBY36852.1 - 0.0076 17.0 0.8 0.026 15.2 0.1 2.3 2 0 0 2 2 2 1 Lectin C-type domain LapA_dom PF06305.11 CBY36853.1 - 0.023 14.5 1.9 6.4 6.7 0.0 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RIIa PF02197.17 CBY36853.1 - 0.034 13.8 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit DUF3096 PF11295.8 CBY36853.1 - 3.2 7.5 10.0 7.5 6.3 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) Collagen PF01391.18 CBY36854.1 - 1.4e-79 261.7 321.8 1.5e-08 34.2 26.5 11.8 4 3 7 11 11 11 11 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY36854.1 - 1.2e-27 97.3 0.0 3.3e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY36854.1 - 0.0004 21.0 0.0 0.0007 20.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Patched PF02460.18 CBY36855.1 - 3.7e-12 45.2 1.2 4.9e-12 44.8 1.2 1.1 1 0 0 1 1 1 1 Patched family PIRT PF15099.6 CBY36855.1 - 0.053 13.1 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family MFS_1 PF07690.16 CBY36857.1 - 7.8e-09 34.9 11.0 1.3e-08 34.2 11.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.19 CBY36857.1 - 0.017 15.1 0.4 0.049 13.7 0.2 1.8 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain B_solenoid_ydck PF18836.1 CBY36857.1 - 0.027 14.3 0.1 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK wnt PF00110.19 CBY36859.1 - 1.7e-71 241.3 29.9 2.2e-71 241.0 29.6 1.2 1 1 0 1 1 1 1 wnt family Thiolase_N PF00108.23 CBY36863.1 - 1.8e-68 230.7 2.2 4.8e-67 226.1 2.6 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY36863.1 - 9.2e-40 135.1 0.0 2.4e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY36863.1 - 6.6e-05 22.6 1.1 0.00017 21.3 0.3 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CBY36863.1 - 0.013 14.2 0.3 0.027 13.2 0.3 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 CBY36863.1 - 0.084 12.9 1.7 1.2 9.2 0.0 3.5 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain EMP70 PF02990.16 CBY36864.1 - 1.1e-142 476.3 19.1 1.3e-142 476.1 19.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 KAP PF05804.12 CBY36865.1 - 4.3e-176 587.1 11.6 5.5e-176 586.8 11.6 1.1 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 CBY36865.1 - 0.01 15.8 3.2 0.47 10.6 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SCO1-SenC PF02630.14 CBY36865.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC DUF383 PF04063.14 CBY36865.1 - 0.24 11.0 3.1 2.8 7.6 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF383) SnAPC_2_like PF11035.8 CBY36866.1 - 9e-07 29.3 0.2 9e-07 29.3 0.2 3.8 2 2 0 3 3 3 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Radical_SAM_N PF08497.10 CBY36866.1 - 0.6 9.3 4.5 0.13 11.5 0.2 1.9 2 0 0 2 2 2 0 Radical SAM N-terminal TPR_1 PF00515.28 CBY36867.1 - 2.6e-17 61.8 10.0 0.00034 20.3 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36867.1 - 1.3e-15 56.1 16.2 0.0086 16.1 0.1 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CBY36867.1 - 1.8e-10 41.2 3.8 0.04 14.4 0.0 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36867.1 - 1.3e-08 35.4 7.1 3.9e-06 27.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36867.1 - 2.6e-08 34.0 7.7 0.17 12.2 0.5 5.4 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36867.1 - 2.8e-08 33.9 6.0 2.5 9.2 0.1 6.4 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36867.1 - 9.8e-07 28.4 6.0 0.01 15.5 0.0 5.4 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 CBY36867.1 - 3.1e-05 23.7 7.2 0.54 10.4 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY36867.1 - 0.00024 21.2 6.0 0.17 12.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY36867.1 - 0.00031 20.1 0.0 0.4 9.8 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36867.1 - 0.0031 17.6 13.0 4.1 7.8 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36867.1 - 0.0046 17.5 6.5 4.8 8.0 0.0 5.3 7 0 0 7 7 4 1 Tetratricopeptide repeat MIT PF04212.18 CBY36867.1 - 0.0057 16.7 5.7 2.2 8.4 0.4 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBY36867.1 - 0.055 13.4 6.0 32 4.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY36867.1 - 0.083 13.3 0.1 29 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY36867.1 - 0.15 11.5 3.1 14 5.3 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR Ribosomal_60s PF00428.19 CBY36868.1 - 3.6e-23 82.0 2.3 4.2e-23 81.8 2.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Anophelin PF10731.9 CBY36868.1 - 0.052 13.4 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito ETC_C1_NDUFA4 PF04800.12 CBY36869.1 - 2.5e-30 104.6 2.4 3.7e-30 104.0 2.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Es2 PF09751.9 CBY36870.1 - 8.3e-56 190.5 12.8 8.3e-56 190.5 12.8 1.9 1 1 1 2 2 2 1 Nuclear protein Es2 PQ-loop PF04193.14 CBY36871.1 - 2.2e-15 56.1 9.7 5.3e-10 38.9 1.9 3.1 2 1 1 3 3 3 2 PQ loop repeat DUF1463 PF07316.11 CBY36872.1 - 0.05 13.4 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) Pyridox_oxase_2 PF12766.7 CBY36873.1 - 0.073 13.7 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SCP2 PF02036.17 CBY36874.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 SCP-2 sterol transfer family Lectin_C PF00059.21 CBY36875.1 - 1.7e-05 25.5 9.8 0.00017 22.3 2.0 2.7 2 0 0 2 2 2 2 Lectin C-type domain Eryth_link_C PF16915.5 CBY36875.1 - 0.4 10.7 2.3 3.9 7.5 0.1 3.2 3 1 1 4 4 4 0 Annelid erythrocruorin linker subunit C-terminus KH_1 PF00013.29 CBY36876.1 - 2.6e-07 30.4 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CBY36876.1 - 0.0018 18.1 0.1 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CBY36876.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 KH domain Pex14_N PF04695.13 CBY36876.1 - 0.028 15.1 4.9 0.031 14.9 4.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med13_C PF06333.12 CBY36876.1 - 0.082 12.2 2.7 0.093 12.0 2.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Pkinase_Tyr PF07714.17 CBY36878.1 - 8.2e-37 126.9 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36878.1 - 1.2e-18 67.4 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 CBY36878.1 - 6.1e-15 55.3 0.0 2.2e-11 44.0 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_lbd PF01404.19 CBY36878.1 - 1.1e-10 41.8 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin receptor ligand binding domain Ephrin_rec_like PF07699.13 CBY36878.1 - 1.9e-05 24.3 10.7 1.9e-05 24.3 10.7 2.8 2 1 0 2 2 2 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 CBY36878.1 - 0.0094 16.5 0.0 8.3 7.1 0.0 2.6 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY36878.1 - 0.11 12.8 0.1 2.8 8.3 0.0 2.4 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Sdh_cyt PF01127.22 CBY36878.1 - 0.12 12.5 1.3 0.17 11.9 0.3 1.7 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PTS_EIIA_1 PF00358.20 CBY36878.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 I-set PF07679.16 CBY36879.1 - 0.0011 19.0 0.0 0.062 13.4 0.0 2.0 1 1 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY36879.1 - 0.049 14.2 0.0 0.086 13.5 0.0 1.4 1 1 0 1 1 1 0 Immunoglobulin domain Strabismus PF06638.11 CBY36880.1 - 7.2e-101 338.3 1.9 9.4e-101 337.9 1.9 1.1 1 0 0 1 1 1 1 Strabismus protein DAGK_acc PF00609.19 CBY36881.1 - 2.1e-34 119.2 0.0 3.9e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBY36881.1 - 4.1e-27 94.3 0.0 6.7e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 CBY36881.1 - 0.00058 19.7 18.1 0.0014 18.5 3.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 CBY36881.1 - 0.02 14.9 5.6 0.029 14.3 1.0 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHD PF00628.29 CBY36881.1 - 0.18 11.7 12.1 0.11 12.4 0.8 3.0 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 CBY36881.1 - 2.5 8.5 10.8 2.8 8.3 0.7 3.0 2 0 0 2 2 2 0 C1 domain PHD_2 PF13831.6 CBY36881.1 - 4.1 7.0 10.1 0.94 9.1 2.6 2.6 2 0 0 2 2 2 0 PHD-finger Cation_ATPase_N PF00690.26 CBY36883.1 - 4.8e-17 61.4 0.0 7.7e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 CBY36883.1 - 2.2e-05 24.1 0.1 0.00041 19.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase E1-E2_ATPase PF00122.20 CBY36884.1 - 1.4e-28 99.6 0.5 2.6e-28 98.8 0.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBY36884.1 - 1.3e-25 89.3 0.0 2.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY36884.1 - 0.036 14.4 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 CBY36884.1 - 0.89 9.6 5.4 1.8 8.7 5.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Homeodomain PF00046.29 CBY36885.1 - 5.5e-16 58.2 4.0 1.1e-15 57.2 4.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY36885.1 - 0.0024 17.7 0.4 0.0076 16.1 0.4 1.9 1 0 0 1 1 1 1 Homeobox KN domain RRM_1 PF00076.22 CBY36886.1 - 1.6e-20 72.7 0.1 4.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CBY36886.1 - 0.0086 16.3 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CBY36886.1 - 0.013 15.6 0.0 0.5 10.5 0.0 2.8 3 1 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBY36886.1 - 0.22 11.5 1.8 18 5.4 0.1 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif EGF_CA PF07645.15 CBY36887.1 - 7.7e-70 230.9 190.9 1.2e-11 44.6 4.3 12.9 13 0 0 13 13 13 11 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY36887.1 - 6.1e-43 144.8 158.2 1.2e-09 38.3 8.0 12.4 9 3 3 12 12 12 8 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY36887.1 - 4.9e-34 115.9 105.3 4.3e-07 29.8 4.0 12.3 12 0 0 12 12 12 9 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY36887.1 - 2.4e-20 72.4 157.4 0.0013 18.8 7.1 13.6 12 2 1 13 13 13 10 EGF domain EGF PF00008.27 CBY36887.1 - 5.2e-13 49.0 146.7 0.00044 20.5 5.2 13.4 12 1 0 12 12 12 9 EGF-like domain Laminin_G_2 PF02210.24 CBY36887.1 - 1.1e-06 29.3 0.1 2.8e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.23 CBY36887.1 - 0.00021 21.5 0.0 0.00039 20.6 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain hEGF PF12661.7 CBY36887.1 - 0.00078 20.0 141.9 0.043 14.5 2.7 15.2 15 2 0 15 15 15 8 Human growth factor-like EGF MBDa PF16564.5 CBY36888.1 - 0.014 15.6 8.5 8.4 6.7 0.1 4.1 3 0 0 3 3 3 0 p55-binding region of Methyl-CpG-binding domain proteins MBD FliG_N PF14842.6 CBY36888.1 - 8.8 6.9 8.0 4.2 8.0 1.1 4.1 4 0 0 4 4 4 0 FliG N-terminal domain HD PF01966.22 CBY36889.1 - 3.2e-09 37.0 0.1 4.5e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 HD domain MIF4G PF02854.19 CBY36890.1 - 2.5e-12 46.9 12.4 2.5e-12 46.9 12.4 1.9 2 0 0 2 2 2 1 MIF4G domain TFIIA PF03153.13 CBY36890.1 - 0.0075 16.3 20.6 0.0075 16.3 20.6 2.4 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1182 PF06681.13 CBY36890.1 - 0.13 11.8 1.3 0.2 11.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Ubiquitin_3 PF14836.6 CBY36890.1 - 0.68 10.0 4.9 2.3 8.3 1.1 3.2 3 1 0 3 3 3 0 Ubiquitin-like domain Pkinase PF00069.25 CBY36891.1 - 6.2e-63 212.6 0.0 9.5e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36891.1 - 1.4e-32 113.0 0.0 2.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.11 CBY36891.1 - 4.9e-24 84.9 0.1 4.9e-24 84.9 0.1 3.0 2 1 0 2 2 1 1 Domain of unknown function (DUF1908) PDZ_6 PF17820.1 CBY36891.1 - 5e-07 29.5 0.0 9.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kinase-like PF14531.6 CBY36891.1 - 2.6e-05 23.7 0.1 0.00084 18.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY36891.1 - 3e-05 24.1 0.0 0.07 13.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PDZ_2 PF13180.6 CBY36891.1 - 5.7e-05 23.4 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBY36891.1 - 0.00012 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Kdo PF06293.14 CBY36891.1 - 0.00014 21.3 0.8 0.0005 19.5 0.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY36891.1 - 0.00029 19.9 4.3 0.0015 17.6 0.2 2.7 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY36891.1 - 0.0097 14.7 0.0 0.027 13.3 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY36891.1 - 0.012 15.3 0.2 0.033 13.8 0.1 1.8 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CBY36891.1 - 0.021 14.4 0.0 0.16 11.6 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1955 PF09205.10 CBY36892.1 - 0.036 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) HSP90 PF00183.18 CBY36894.1 - 4.4e-98 329.4 10.1 2.2e-95 320.5 6.3 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CBY36894.1 - 2.9e-12 46.6 0.1 5.7e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY36894.1 - 1.5e-08 35.1 0.1 3.1e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HeH PF12949.7 CBY36895.1 - 1.3e-08 34.4 0.9 2.1e-08 33.7 0.9 1.4 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 CBY36895.1 - 0.031 14.0 0.2 0.063 13.0 0.2 1.6 1 0 0 1 1 1 0 SAP domain zf-RING_2 PF13639.6 CBY36896.1 - 1.3e-10 41.4 3.1 2.4e-10 40.6 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY36896.1 - 2.3e-09 36.9 3.6 4.7e-09 35.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY36896.1 - 1.1e-07 31.6 3.0 2.3e-07 30.6 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY36896.1 - 5.2e-06 26.7 2.2 1.7e-05 25.0 2.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY36896.1 - 8.2e-06 25.6 1.7 1.4e-05 24.9 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY36896.1 - 2.9e-05 23.9 3.8 5.5e-05 23.0 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY36896.1 - 8.2e-05 22.5 4.7 8.2e-05 22.5 4.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger GAS PF13851.6 CBY36896.1 - 0.001 18.5 80.3 0.028 13.8 16.7 4.2 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 CBY36896.1 - 0.0019 17.8 17.8 0.0019 17.8 17.8 3.7 1 1 3 4 4 3 1 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CBY36896.1 - 0.002 18.2 12.8 0.002 18.2 12.8 4.4 3 2 1 4 4 4 1 TPR/MLP1/MLP2-like protein zf-RING_11 PF17123.5 CBY36896.1 - 0.0023 17.6 3.3 0.019 14.7 1.0 2.7 2 0 0 2 2 2 1 RING-like zinc finger Baculo_IE-1 PF05290.11 CBY36896.1 - 0.0082 16.1 0.9 0.0082 16.1 0.9 2.4 1 1 2 3 3 3 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CBY36896.1 - 0.014 15.2 2.3 0.028 14.3 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HALZ PF02183.18 CBY36896.1 - 0.035 14.3 0.4 0.035 14.3 0.4 7.4 6 1 0 7 7 7 0 Homeobox associated leucine zipper zf-RING_4 PF14570.6 CBY36896.1 - 0.058 13.2 6.6 0.031 14.1 4.3 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CBY36896.1 - 0.2 11.7 1.2 0.39 10.8 1.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBY36896.1 - 0.41 10.8 3.8 1.4 9.2 3.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Trans_reg_C PF00486.28 CBY36896.1 - 0.95 9.6 6.1 1.2 9.3 0.2 3.2 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal O-FucT PF10250.9 CBY36897.1 - 0.037 13.7 5.4 2.4 7.7 0.0 2.4 1 1 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase GD_AH_C PF04295.13 CBY36897.1 - 0.064 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus AMP-binding PF00501.28 CBY36898.1 - 3.8e-59 200.4 0.0 4.8e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY36898.1 - 1.1e-14 55.2 0.2 2.3e-14 54.1 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP PF00188.26 CBY36899.1 - 0.00015 22.6 0.0 0.00027 21.8 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_49 PF13896.6 CBY36900.1 - 5.4e-89 298.8 0.3 1.1e-88 297.8 0.2 1.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Cep57_CLD_2 PF14197.6 CBY36904.1 - 0.003 17.6 3.4 0.007 16.4 3.4 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Scaffolding_pro PF11418.8 CBY36904.1 - 0.27 11.8 4.4 0.15 12.6 1.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein ZapB PF06005.12 CBY36904.1 - 0.55 10.7 7.8 0.077 13.4 3.6 1.8 2 0 0 2 2 2 0 Cell division protein ZapB zf-CpG_bind_C PF12269.8 CBY36904.1 - 6.2 6.5 7.1 1.3 8.7 2.2 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Septin PF00735.18 CBY36906.1 - 0.00012 21.5 0.2 0.00033 20.0 0.2 1.6 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.27 CBY36906.1 - 0.00021 20.9 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY36906.1 - 0.00024 21.1 0.0 0.00079 19.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBY36906.1 - 0.00061 19.9 0.0 0.33 11.0 0.0 2.8 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 CBY36906.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 CBY36906.1 - 0.0079 15.4 0.1 0.26 10.4 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 CBY36906.1 - 0.0079 16.6 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CBY36906.1 - 0.029 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 CBY36906.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CBY36906.1 - 0.18 11.6 0.0 0.84 9.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY36906.1 - 0.28 11.6 1.1 1.3 9.5 1.1 2.1 1 1 0 1 1 1 0 AAA domain LSM PF01423.22 CBY36907.1 - 8.5e-20 70.2 0.0 1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain CAF1 PF04857.20 CBY36908.1 - 2.1e-29 102.7 0.2 2.7e-29 102.4 0.2 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 CBY36908.1 - 9.7e-17 60.8 0.7 3.2e-16 59.1 0.3 2.0 2 0 0 2 2 2 1 RNA binding domain R3H PF01424.22 CBY36908.1 - 0.00033 20.6 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain DUF1688 PF07958.11 CBY36908.1 - 0.15 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) MAS20 PF02064.15 CBY36908.1 - 1.6 8.8 5.1 3.2 7.9 3.2 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor CSTF_C PF14304.6 CBY36909.1 - 7.2e-16 57.5 4.2 7.2e-16 57.5 4.2 1.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Galactosyl_T PF01762.21 CBY36911.1 - 5.2e-26 91.7 0.0 1.1e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 Galactosyltransferase Chitin_bind_1 PF00187.19 CBY36911.1 - 0.026 15.0 21.1 0.12 12.9 20.2 2.4 1 1 1 2 2 2 0 Chitin recognition protein Peptidase_M1 PF01433.20 CBY36912.1 - 9.2e-47 159.4 0.2 2.1e-46 158.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY36912.1 - 5.6e-22 78.8 2.9 7.3e-22 78.5 0.4 2.3 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain ATP-gua_Ptrans PF00217.19 CBY36915.1 - 2.7e-63 213.3 0.0 3.2e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain SAP PF02037.27 CBY36915.1 - 0.13 12.1 0.2 1 9.2 0.1 2.4 2 0 0 2 2 2 0 SAP domain Podoplanin PF05808.11 CBY36916.1 - 5.5e-05 23.3 2.7 6.2e-05 23.2 2.7 1.2 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.13 CBY36916.1 - 0.00081 20.0 3.1 0.0012 19.4 3.1 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J DUF4366 PF14283.6 CBY36916.1 - 0.0036 17.4 0.5 0.0049 16.9 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Myc_N PF01056.18 CBY36916.1 - 0.0065 16.4 3.9 0.0073 16.2 3.9 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Sec3_C PF09763.9 CBY36916.1 - 0.0072 14.8 0.5 0.0083 14.6 0.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 BES1_N PF05687.13 CBY36916.1 - 0.013 15.9 8.8 0.018 15.4 8.8 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal DUF5305 PF17231.2 CBY36916.1 - 0.018 14.4 3.2 0.027 13.9 3.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Apt1 PF10351.9 CBY36916.1 - 0.03 13.2 3.3 0.03 13.2 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM154 PF15102.6 CBY36916.1 - 0.035 14.0 8.5 0.095 12.6 8.5 1.7 1 1 0 1 1 1 0 TMEM154 protein family Reprolysin_3 PF13582.6 CBY36916.1 - 0.047 14.2 0.6 0.089 13.3 0.6 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3827 PF12877.7 CBY36916.1 - 0.086 11.2 3.0 0.089 11.2 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Miga PF10265.9 CBY36916.1 - 0.19 10.7 7.4 0.25 10.3 7.4 1.1 1 0 0 1 1 1 0 Mitoguardin Smg8_Smg9 PF10220.9 CBY36916.1 - 0.25 9.6 2.8 0.27 9.5 2.8 1.0 1 0 0 1 1 1 0 Smg8_Smg9 GEMIN8 PF15348.6 CBY36916.1 - 0.35 11.1 3.4 0.41 10.9 3.4 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Macoilin PF09726.9 CBY36916.1 - 1.6 7.2 8.5 2 6.9 8.5 1.1 1 0 0 1 1 1 0 Macoilin family MGC-24 PF05283.11 CBY36916.1 - 1.7 9.1 13.8 2.6 8.5 13.8 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Presenilin PF01080.17 CBY36916.1 - 1.7 7.3 4.9 2.2 7.0 4.9 1.1 1 0 0 1 1 1 0 Presenilin DHHW PF14286.6 CBY36916.1 - 6.1 6.1 8.6 8.4 5.6 8.6 1.2 1 0 0 1 1 1 0 DHHW protein NAM-associated PF14303.6 CBY36916.1 - 6.3 7.5 9.0 9.8 6.9 9.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RAP1 PF07218.11 CBY36916.1 - 7 4.8 16.2 8.8 4.5 16.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Zona_pellucida PF00100.23 CBY36917.1 - 1.2e-16 61.3 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain SecE PF00584.20 CBY36918.1 - 5.6e-14 51.8 0.2 6.3e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Enkurin PF13864.6 CBY36919.1 - 5.1e-24 84.6 2.0 5.7e-24 84.4 2.0 1.0 1 0 0 1 1 1 1 Calmodulin-binding Cob_adeno_trans PF01923.18 CBY36919.1 - 0.063 13.4 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IDEAL PF08858.10 CBY36919.1 - 0.16 11.7 2.8 36 4.2 0.1 3.3 3 0 0 3 3 3 0 IDEAL domain ABC_tran_CTD PF16326.5 CBY36919.1 - 3.8 7.8 11.7 0.92 9.8 1.2 2.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain ATP_transf PF09830.9 CBY36920.1 - 0.14 12.3 0.2 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP adenylyltransferase PAP2 PF01569.21 CBY36921.1 - 1.4e-23 83.1 2.5 3.4e-23 81.9 1.0 2.2 2 1 0 2 2 2 1 PAP2 superfamily Cation_efflux PF01545.21 CBY36921.1 - 0.00048 19.9 0.2 0.005 16.6 0.1 2.1 2 0 0 2 2 2 1 Cation efflux family DUF4234 PF14018.6 CBY36921.1 - 0.016 15.3 1.0 0.049 13.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF212 PF02681.14 CBY36921.1 - 0.44 10.7 2.4 7.7 6.7 0.1 2.5 3 0 0 3 3 3 0 Divergent PAP2 family DUF485 PF04341.12 CBY36921.1 - 1.3 9.0 4.1 13 5.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 APG6_N PF17675.1 CBY36922.1 - 2.6 8.6 17.3 0.32 11.5 12.2 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region SMK-1 PF04802.15 CBY36923.1 - 1.9e-50 171.4 9.1 1.9e-50 171.4 9.1 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Ran_BP1 PF00638.18 CBY36923.1 - 0.001 19.3 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CBY36923.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 WH1 domain DUF2433 PF10360.9 CBY36923.1 - 0.13 12.4 2.3 4.4 7.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) Pkinase PF00069.25 CBY36924.1 - 1e-54 185.7 0.0 1e-53 182.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY36924.1 - 1.9e-24 86.3 0.0 3.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY36924.1 - 7.2e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY36924.1 - 0.0006 19.2 0.8 0.0016 17.8 0.8 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY36924.1 - 0.0012 18.5 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Ribos_L4_asso_C PF14374.6 CBY36924.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.4 4 0 0 4 4 4 1 60S ribosomal protein L4 C-terminal domain FTA2 PF13095.6 CBY36924.1 - 0.046 13.3 0.4 0.09 12.4 0.0 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY36924.1 - 0.08 12.9 0.2 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Claudin_2 PF13903.6 CBY36925.1 - 1.2e-05 25.2 1.5 1.5e-05 24.9 1.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF5090 PF17009.5 CBY36925.1 - 0.00029 20.9 0.2 0.00038 20.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) TssN PF17555.2 CBY36925.1 - 0.072 12.5 1.8 0.12 11.7 1.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2070 PF09843.9 CBY36925.1 - 0.57 8.4 6.8 0.81 7.9 6.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) OATP PF03137.20 CBY36926.1 - 3.5e-153 510.8 15.6 4e-153 510.6 15.6 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY36926.1 - 3.4e-18 65.7 18.2 3.4e-18 65.7 18.2 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily GWT1 PF06423.12 CBY36926.1 - 0.029 14.5 0.4 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 GWT1 Astacin PF01400.24 CBY36927.1 - 2.2e-11 43.7 0.0 6e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY36927.1 - 0.013 15.7 0.7 0.042 14.1 0.7 1.9 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF2850 PF11012.8 CBY36928.1 - 0.015 15.6 0.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) TAFA PF12020.8 CBY36928.1 - 0.25 11.8 7.0 14 6.2 0.0 4.5 4 0 0 4 4 4 0 TAFA family Myosin_tail_1 PF01576.19 CBY36934.1 - 3.1e-137 459.1 273.8 4e-137 458.8 273.8 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_head PF00063.21 CBY36934.1 - 3.7e-73 246.9 0.0 3.7e-73 246.9 0.0 3.4 3 1 0 3 3 3 1 Myosin head (motor domain) Guanylate_cyc PF00211.20 CBY36935.1 - 2.5e-40 138.1 0.0 3.3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RhoGEF PF00621.20 CBY36936.1 - 1.9e-19 70.6 6.2 3.4e-19 69.8 6.2 1.5 1 1 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 CBY36936.1 - 6.9e-10 38.5 0.1 1.3e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY36936.1 - 7e-10 38.4 0.4 1.3e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY36936.1 - 1.5e-08 34.4 0.1 2.4e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PBP1_TM PF14812.6 CBY36937.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cofilin_ADF PF00241.20 CBY36938.1 - 2.6e-34 117.6 0.3 4e-18 65.4 0.1 2.3 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein HCO3_cotransp PF00955.21 CBY36939.1 - 6.6e-217 721.3 9.9 8.1e-217 721.0 9.9 1.1 1 0 0 1 1 1 1 HCO3- transporter family Band_3_cyto PF07565.13 CBY36939.1 - 4.4e-33 115.2 0.0 6.4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF4813 PF16072.5 CBY36940.1 - 0.18 11.4 9.7 0.24 11.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF5089 PF17002.5 CBY36941.1 - 2.2e-06 27.7 3.7 4.2e-06 26.8 3.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) SNAP-25 PF00835.19 CBY36941.1 - 5e-06 26.7 2.2 6.9e-06 26.3 0.8 2.1 2 0 0 2 2 2 1 SNAP-25 family V-SNARE_C PF12352.8 CBY36941.1 - 0.0014 18.9 4.6 0.034 14.4 0.8 2.4 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBY36941.1 - 0.017 15.0 0.9 0.042 13.8 0.8 1.6 2 0 0 2 2 2 0 Sec20 SNARE PF05739.19 CBY36941.1 - 0.053 13.5 1.6 0.17 11.9 1.6 2.0 1 1 0 1 1 1 0 SNARE domain UPF0242 PF06785.11 CBY36941.1 - 0.12 12.5 4.3 0.53 10.4 2.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY36941.1 - 0.26 11.3 2.1 4.6 7.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY36941.1 - 0.28 11.6 3.0 12 6.4 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 CBY36941.1 - 0.54 10.5 6.6 0.54 10.5 0.9 2.9 2 1 1 3 3 3 0 Haemolysin XhlA GAS PF13851.6 CBY36941.1 - 1.1 8.6 7.7 3.4 7.0 0.0 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding SH3_11 PF18103.1 CBY36942.1 - 0.048 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain zf-Di19 PF05605.12 CBY36942.1 - 0.14 12.4 1.1 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BBL5 PF07289.11 CBY36943.1 - 7.3e-117 390.1 0.1 8.3e-117 389.9 0.1 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 CBY36943.1 - 0.0017 18.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 CBY36943.1 - 0.017 15.4 0.0 9.7 6.6 0.0 2.3 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain TAFH PF07531.14 CBY36944.1 - 1.2e-21 76.6 6.4 6.1e-21 74.3 3.5 3.0 2 1 0 2 2 2 1 NHR1 homology to TAF TAF4 PF05236.14 CBY36944.1 - 1.5e-20 74.1 16.7 3.3e-18 66.4 13.9 2.7 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 CBY36944.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.6 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Ada3 PF10198.9 CBY36945.1 - 0.012 15.7 11.8 0.012 15.7 11.8 1.9 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Erf4 PF10256.9 CBY36946.1 - 2.1e-17 63.3 0.1 2.5e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Dynamin_N PF00350.23 CBY36947.1 - 1.7e-05 25.0 0.1 2.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY36947.1 - 0.003 17.6 0.1 0.0047 17.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBY36947.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBY36947.1 - 0.0038 17.1 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 CBY36947.1 - 0.017 14.4 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.14 CBY36947.1 - 0.065 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 CBY36947.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 CBY36947.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SET PF00856.28 CBY36948.1 - 9.6e-07 29.3 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 SET domain Gin PF10764.9 CBY36948.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Gal4_dimer PF03902.13 CBY36949.1 - 0.035 14.3 0.2 0.28 11.4 0.1 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain Pkinase_Tyr PF07714.17 CBY36950.1 - 5e-63 212.8 0.0 9.8e-63 211.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY36950.1 - 5.5e-39 134.1 0.0 1.1e-38 133.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Glyco_tranf_2_3 PF13641.6 CBY36950.1 - 1e-21 77.9 0.0 1.8e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY36950.1 - 1.5e-16 60.9 1.4 1.5e-16 60.9 1.4 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_hydro_6 PF01341.17 CBY36950.1 - 3.4e-15 56.6 0.0 1.9e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 6 Glycos_transf_2 PF00535.26 CBY36950.1 - 1.8e-14 53.9 0.0 3.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CBY36950.1 - 3.3e-08 33.2 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 CBY36950.1 - 2.4e-07 29.7 7.4 0.00058 18.5 4.6 2.3 1 1 1 2 2 2 2 Cellulose synthase Sigma_M_inh PF17453.2 CBY36950.1 - 0.027 14.9 0.8 6 7.4 0.0 3.5 3 0 0 3 3 3 0 Sigma-M inhibitor Toxin_YhaV PF11663.8 CBY36950.1 - 0.099 12.7 0.2 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system Kinase-like PF14531.6 CBY36950.1 - 0.16 11.3 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like EF-hand_8 PF13833.6 CBY36951.1 - 3.2e-08 33.3 8.3 1.3e-07 31.4 4.2 3.5 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY36951.1 - 4.5e-08 33.4 7.0 1.9e-07 31.4 3.7 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY36951.1 - 5.7e-08 31.8 14.2 0.00018 20.8 2.6 4.2 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY36951.1 - 2.6e-07 30.0 7.1 0.0028 17.5 0.5 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY36951.1 - 3.4e-05 23.1 9.9 0.0025 17.3 1.9 3.5 4 0 0 4 4 4 2 EF hand DUF3884 PF13024.6 CBY36951.1 - 0.027 14.0 0.1 0.15 11.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3884) EF-hand_4 PF12763.7 CBY36951.1 - 0.041 13.8 2.1 0.057 13.4 1.0 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY36951.1 - 0.18 12.7 0.5 0.43 11.5 0.3 1.7 2 0 0 2 2 2 0 EF-hand domain Lectin_C PF00059.21 CBY36952.1 - 1.3e-07 32.4 1.5 2.1e-07 31.6 1.5 1.3 1 0 0 1 1 1 1 Lectin C-type domain Sulfotransfer_1 PF00685.27 CBY36953.1 - 4.5e-09 36.2 0.0 1.8e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY36953.1 - 6.1e-06 26.8 0.1 3.2e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Sulfotransferase family Somatomedin_B PF01033.17 CBY36953.1 - 1e-05 25.8 13.6 1e-05 25.8 13.6 2.3 2 0 0 2 2 2 1 Somatomedin B domain DS PF01916.17 CBY36954.1 - 0.024 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Deoxyhypusine synthase EnY2 PF10163.9 CBY36954.1 - 0.08 13.3 0.9 0.14 12.5 0.9 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Forkhead PF00250.18 CBY36955.1 - 2.3e-37 127.1 0.3 6.1e-37 125.8 0.3 1.8 1 0 0 1 1 1 1 Forkhead domain Apt1 PF10351.9 CBY36956.1 - 0.0069 15.3 0.3 0.008 15.1 0.3 1.2 1 1 0 1 1 1 1 Golgi-body localisation protein domain Sugar_tr PF00083.24 CBY36957.1 - 2.2e-12 46.6 2.9 3.1e-12 46.1 2.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY36957.1 - 2.8e-08 33.1 10.7 5.2e-08 32.2 10.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribonuc_2-5A PF06479.12 CBY36958.1 - 1.7e-11 44.4 2.5 2.5e-11 43.9 0.3 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A LAS2 PF15792.5 CBY36958.1 - 0.087 13.4 1.5 0.44 11.1 0.1 2.6 3 0 0 3 3 3 0 Lung adenoma susceptibility protein 2 Peptidase_C1 PF00112.23 CBY36959.1 - 2.2e-35 122.7 0.3 3.9e-35 121.9 0.3 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY36959.1 - 3e-15 56.4 3.3 4.7e-15 55.8 3.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) GDA1_CD39 PF01150.17 CBY36960.1 - 1.2e-68 231.7 0.0 5.4e-67 226.3 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C1 PF00112.23 CBY36961.1 - 2.4e-72 243.5 5.3 3.7e-72 243.0 5.3 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY36961.1 - 1.8e-12 47.5 4.5 3.3e-12 46.6 4.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBY36961.1 - 9.1e-06 24.7 1.8 0.0025 16.6 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBY36961.1 - 0.00013 21.8 0.3 0.00029 20.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Sulfotransfer_2 PF03567.14 CBY36963.1 - 1.1e-15 58.2 0.1 1.6e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family zf-C2H2_4 PF13894.6 CBY36965.1 - 0.0017 19.1 8.5 0.53 11.3 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY36965.1 - 0.014 15.8 0.7 0.014 15.8 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L37ae PF01780.19 CBY36965.1 - 0.023 14.8 1.6 0.6 10.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 CBY36965.1 - 0.023 15.1 7.8 0.68 10.5 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 CBY36965.1 - 0.025 15.0 9.5 0.15 12.6 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 CBY36965.1 - 0.074 13.0 1.9 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 CBY36965.1 - 0.11 12.8 4.1 1.1 9.6 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY36965.1 - 0.14 12.5 0.7 0.14 12.5 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Na_Pi_cotrans PF02690.15 CBY36967.1 - 3.2e-32 111.5 27.1 3.9e-19 69.1 8.4 2.8 3 0 0 3 3 3 2 Na+/Pi-cotransporter P4Ha_N PF08336.11 CBY36968.1 - 6.1e-23 81.3 1.3 6.1e-23 81.3 1.3 1.7 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY36968.1 - 1.4e-13 51.5 0.1 1.2e-12 48.6 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_6 PF13174.6 CBY36968.1 - 0.098 13.3 0.6 0.61 10.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY36969.1 - 9.1e-17 61.1 9.6 3.1e-06 27.4 0.7 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY36969.1 - 5e-11 41.8 13.6 0.15 12.2 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY36969.1 - 1.1e-09 38.3 7.3 0.00019 21.6 0.3 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBY36969.1 - 7.9e-08 31.8 15.1 0.0051 16.6 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY36969.1 - 1.8e-06 27.5 1.5 0.068 12.9 0.0 4.4 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 CBY36969.1 - 6.2e-06 26.6 9.4 0.094 13.2 0.0 5.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY36969.1 - 8.7e-06 26.3 5.6 0.0057 17.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 CBY36969.1 - 4.6e-05 23.2 8.2 0.00028 20.6 3.6 2.9 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 CBY36969.1 - 0.00013 21.7 9.6 0.28 11.3 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY36969.1 - 0.00024 21.6 9.1 11 7.2 0.1 6.3 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY36969.1 - 0.00061 19.8 13.2 1.9 8.9 0.2 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY36969.1 - 0.0046 16.4 2.9 0.022 14.1 3.0 1.8 2 0 0 2 2 2 1 MalT-like TPR region ANTH PF07651.16 CBY36969.1 - 0.0069 15.4 0.3 0.011 14.8 0.3 1.4 1 0 0 1 1 1 1 ANTH domain TPR_17 PF13431.6 CBY36969.1 - 0.024 15.0 4.5 3.2 8.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBY36969.1 - 0.033 14.8 2.5 19 6.3 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBY36969.1 - 0.064 13.0 6.9 1.4 8.6 4.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CBY36969.1 - 0.16 11.9 13.7 0.22 11.4 0.5 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY36969.1 - 0.92 10.3 9.2 43 5.0 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat CI-B14_5a PF07347.12 CBY36971.1 - 1.2e-11 44.4 0.4 1.6e-11 44.0 0.4 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Ank_2 PF12796.7 CBY36972.1 - 1.4e-07 32.0 0.5 4.4e-07 30.4 0.3 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY36972.1 - 2.7e-07 30.3 0.1 0.00083 19.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY36972.1 - 3.5e-06 27.2 0.1 0.00011 22.4 0.1 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 CBY36972.1 - 5.7e-06 26.9 0.0 6e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ank_4 PF13637.6 CBY36972.1 - 4.9e-05 23.8 0.0 0.0019 18.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY36972.1 - 0.0029 18.0 0.2 0.13 12.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_11 PF08241.12 CBY36972.1 - 0.0045 17.6 0.0 0.017 15.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MqsR_toxin PF15723.5 CBY36972.1 - 0.0051 17.2 0.4 19 5.7 0.0 3.6 3 0 0 3 3 3 1 Motility quorum-sensing regulator, toxin of MqsA Methyltransf_24 PF13578.6 CBY36972.1 - 0.32 12.1 1.7 1.9 9.6 1.7 2.5 1 1 0 1 1 1 0 Methyltransferase domain Kelch_5 PF13854.6 CBY36974.1 - 1.9e-10 40.5 0.0 1.5e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY36974.1 - 4.8e-08 32.9 0.1 0.008 16.2 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY36974.1 - 1.2e-06 28.6 0.0 0.0048 17.1 0.0 2.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY36974.1 - 0.0017 17.9 0.0 0.07 12.7 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CBY36974.1 - 0.017 15.4 0.0 0.051 13.9 0.0 1.7 2 0 0 2 2 2 0 Kelch motif Ion_trans_2 PF07885.16 CBY36975.1 - 6.2e-10 38.9 2.4 6.2e-10 38.9 2.4 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY36975.1 - 7.3e-09 35.6 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 CBY36975.1 - 1.2e-08 34.5 6.5 1.8e-08 33.9 6.5 1.2 1 0 0 1 1 1 1 Ion transport protein Vps52 PF04129.12 CBY36976.1 - 0.0039 16.0 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Presenilin PF01080.17 CBY36977.1 - 1.4 7.6 5.7 1.5 7.5 5.7 1.1 1 0 0 1 1 1 0 Presenilin Na_H_Exchanger PF00999.21 CBY36978.1 - 3e-18 65.8 12.0 3.5e-18 65.6 12.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ion_trans PF00520.31 CBY36979.1 - 0.00011 21.5 0.4 0.00015 21.1 0.1 1.4 2 0 0 2 2 2 1 Ion transport protein SKA1 PF07160.12 CBY36979.1 - 0.024 14.5 0.8 0.033 14.0 0.8 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 YabA PF06156.13 CBY36979.1 - 0.033 14.8 0.2 0.072 13.7 0.2 1.6 1 1 0 1 1 1 0 Initiation control protein YabA TrmO_C PF18389.1 CBY36979.1 - 0.036 14.2 1.1 0.075 13.2 0.3 1.9 2 0 0 2 2 2 0 TrmO C-terminal domain Kelch_1 PF01344.25 CBY36980.1 - 0.0013 18.3 0.2 0.1 12.2 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY36980.1 - 0.0018 18.5 0.3 2 8.8 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY36980.1 - 0.068 13.2 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Phospholip_A2_1 PF00068.19 CBY36981.1 - 6.6e-06 26.6 0.3 6.6e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 Phospholipase A2 Big_7 PF17957.1 CBY36982.1 - 0.016 15.9 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig domain zf-C2H2 PF00096.26 CBY36983.1 - 2.7e-07 30.7 7.6 0.0029 18.0 1.4 2.6 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY36983.1 - 3.2e-06 27.3 3.1 7.3e-05 23.0 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY36983.1 - 9.2e-06 25.8 0.3 0.056 13.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY36983.1 - 2.3e-05 25.1 0.1 0.094 13.4 0.0 2.3 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CBY36983.1 - 4.5e-05 23.9 4.2 0.16 12.8 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY36983.1 - 0.00055 19.6 3.3 0.031 14.0 0.1 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY36983.1 - 0.011 16.1 0.1 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CBY36983.1 - 0.02 15.2 2.7 1.8 8.9 0.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon But2 PF09792.9 CBY36983.1 - 0.044 14.2 0.2 0.066 13.6 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain Actin_micro PF17003.5 CBY36983.1 - 0.056 12.6 0.1 9.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family Sulfotransfer_2 PF03567.14 CBY36984.1 - 2.6e-19 70.1 1.1 2.7e-19 70.1 0.1 1.6 2 0 0 2 2 2 1 Sulfotransferase family PLAC8 PF04749.17 CBY36985.1 - 3.9e-18 66.3 6.1 6.1e-18 65.7 6.1 1.2 1 0 0 1 1 1 1 PLAC8 family BacA PF02673.18 CBY36985.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Bacitracin resistance protein BacA Astacin PF01400.24 CBY36986.1 - 2.4e-34 118.6 0.0 2.7e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CBY36986.1 - 1.4e-05 24.8 0.1 1.6e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CBY36986.1 - 0.00075 20.0 0.4 0.001 19.6 0.4 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBY36986.1 - 0.0093 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 CBY36986.1 - 0.017 15.3 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CBY36986.1 - 0.028 13.6 0.4 0.041 13.1 0.4 1.2 1 0 0 1 1 1 0 Met-zincin DUF3152 PF11350.8 CBY36986.1 - 0.042 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.6 CBY36986.1 - 0.059 13.3 0.1 0.064 13.1 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 CBY36986.1 - 0.099 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin PTR2 PF00854.21 CBY36987.1 - 9.6e-71 238.7 18.8 1.3e-30 106.6 1.2 3.1 2 1 1 3 3 3 3 POT family TMEM52 PF14979.6 CBY36988.1 - 1.2 9.1 7.4 1.6 8.7 7.4 1.2 1 0 0 1 1 1 0 Transmembrane 52 SPT6_acidic PF14632.6 CBY36989.1 - 4.6 7.9 18.4 10 6.8 18.4 1.8 1 1 0 1 1 1 0 Acidic N-terminal SPT6 GAS PF13851.6 CBY36990.1 - 4.5e-06 26.1 17.4 4.5e-06 26.1 17.4 6.4 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 CBY36990.1 - 0.0035 16.1 23.5 0.0035 16.1 23.5 3.9 2 2 2 4 4 4 1 AAA domain HALZ PF02183.18 CBY36990.1 - 0.007 16.6 0.3 0.007 16.6 0.3 8.4 7 4 2 9 9 9 2 Homeobox associated leucine zipper TSC22 PF01166.18 CBY36990.1 - 0.17 12.3 0.2 0.17 12.3 0.2 6.8 6 1 1 7 7 7 0 TSC-22/dip/bun family APC_N_CC PF16689.5 CBY36990.1 - 0.79 9.8 17.6 0.23 11.6 2.1 5.1 4 1 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain BLOC1_2 PF10046.9 CBY36990.1 - 8 6.8 40.5 0.3 11.4 3.7 6.4 2 1 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APS_kinase PF01583.20 CBY36991.1 - 3.8e-70 234.8 0.0 6.6e-70 234.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 CBY36991.1 - 6.1e-65 218.6 0.0 8.3e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CBY36991.1 - 2.8e-46 157.1 0.0 4.7e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.6 CBY36991.1 - 7.7e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CBY36991.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CBY36991.1 - 0.0041 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY36991.1 - 0.007 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 CBY36991.1 - 0.025 13.6 0.0 0.055 12.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 CBY36991.1 - 0.029 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase RsgA_GTPase PF03193.16 CBY36991.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 CBY36991.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 CBY36991.1 - 0.056 13.9 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBY36991.1 - 0.095 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 1 0 NTPase Zeta_toxin PF06414.12 CBY36991.1 - 0.11 11.8 0.0 0.55 9.5 0.0 2.1 3 0 0 3 3 3 0 Zeta toxin CTP_transf_like PF01467.26 CBY36991.1 - 0.11 12.7 0.0 6.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Cytidylyltransferase-like SRP54 PF00448.22 CBY36991.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CBY36991.1 - 0.2 12.2 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter HEAT_EZ PF13513.6 CBY36992.1 - 0.0039 17.7 0.1 0.36 11.4 0.1 2.9 1 1 1 2 2 2 2 HEAT-like repeat Cnd1 PF12717.7 CBY36992.1 - 0.05 13.6 1.8 0.057 13.5 0.4 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PRRSV_Env PF02340.15 CBY36992.1 - 0.11 11.8 0.6 47 3.2 0.0 3.0 3 0 0 3 3 3 0 PRRSV putative envelope protein SAPS PF04499.15 CBY36992.1 - 0.35 9.6 4.0 0.067 12.0 0.5 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein TPR_MLP1_2 PF07926.12 CBY36993.1 - 0.0054 16.8 12.7 0.031 14.3 4.4 2.5 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CBY36993.1 - 0.0057 16.7 11.9 0.0057 16.7 11.9 1.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 CBY36993.1 - 0.026 14.6 4.7 0.026 14.6 4.7 2.1 1 1 0 2 2 2 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 CBY36993.1 - 0.033 14.3 1.2 0.065 13.3 0.9 1.7 1 1 0 1 1 1 0 MbeD/MobD like MCPsignal PF00015.21 CBY36993.1 - 0.054 13.3 2.9 0.05 13.4 1.6 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DMPK_coil PF08826.10 CBY36993.1 - 0.067 13.3 5.0 4.9 7.3 0.7 3.1 1 1 2 3 3 3 0 DMPK coiled coil domain like DUF2913 PF11140.8 CBY36993.1 - 0.11 12.3 2.6 0.14 11.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Fib_alpha PF08702.10 CBY36993.1 - 0.11 12.7 8.4 1.7 8.9 1.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CBY36993.1 - 0.15 12.3 8.7 1.9 8.7 2.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.6 CBY36993.1 - 0.16 12.4 10.1 0.29 11.6 9.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) WXG100 PF06013.12 CBY36993.1 - 0.2 11.9 3.4 0.4 10.9 0.7 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF4238 PF14022.6 CBY36993.1 - 0.23 11.0 2.9 0.25 10.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DASH_Spc34 PF08657.10 CBY36993.1 - 0.24 11.2 8.7 0.31 10.8 8.7 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF1664 PF07889.12 CBY36993.1 - 0.39 10.8 6.3 0.87 9.6 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CBY36993.1 - 0.51 10.5 16.2 0.83 9.8 16.2 1.4 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.12 CBY36993.1 - 0.66 10.5 6.4 1.8 9.1 2.3 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 CBY36993.1 - 0.74 9.2 14.4 1.1 8.6 13.9 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 CBY36993.1 - 0.84 9.9 14.8 5.5 7.2 1.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 CBY36993.1 - 0.99 10.1 7.4 1.4 9.6 1.3 2.5 2 1 0 2 2 2 0 SlyX CLZ PF16526.5 CBY36993.1 - 1 9.8 8.2 1 9.8 2.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 CBY36993.1 - 1.6 8.4 8.4 0.92 9.2 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4200 PF13863.6 CBY36993.1 - 1.8 9.0 13.9 0.68 10.3 10.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 CBY36993.1 - 2.7 8.3 10.5 1 9.6 3.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 CBY36993.1 - 2.8 7.2 12.1 6.1 6.1 12.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CBY36993.1 - 3.4 5.5 10.1 3.8 5.3 10.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 CBY36993.1 - 5.1 7.2 13.2 8 6.5 13.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 CBY36993.1 - 6.1 6.0 9.1 4.9 6.3 7.5 1.5 1 1 1 2 2 2 0 TMPIT-like protein FAM76 PF16046.5 CBY36993.1 - 9 5.6 10.7 10 5.4 10.7 1.1 1 0 0 1 1 1 0 FAM76 protein Ras PF00071.22 CBY36994.1 - 1.8e-57 193.5 0.0 2.1e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY36994.1 - 9.7e-32 109.7 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY36994.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY36994.1 - 1.7e-05 24.9 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY36994.1 - 0.00035 20.5 0.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBY36994.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY36994.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CBY36994.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 CBY36994.1 - 0.13 12.6 0.0 0.63 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 CBY36994.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain Phage_GP20 PF06810.11 CBY36995.1 - 0.034 13.9 8.3 0.039 13.8 8.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 CBY36995.1 - 0.046 14.1 8.6 0.037 14.4 7.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Tho2 PF11262.8 CBY36995.1 - 0.29 10.3 6.8 0.3 10.2 6.8 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 CBY36995.1 - 1.7 7.8 5.9 1.9 7.6 5.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran PF00005.27 CBY36996.1 - 2e-20 73.7 0.0 4.3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 CBY36996.1 - 1.7e-19 70.3 0.2 2.6e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_21 PF13304.6 CBY36996.1 - 7.1e-08 32.6 0.3 1.5e-07 31.5 0.1 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY36996.1 - 0.00048 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CBY36996.1 - 0.0016 17.9 0.3 0.0055 16.2 0.2 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBY36996.1 - 0.0027 18.2 1.8 0.0036 17.8 0.2 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY36996.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Lon_2 PF13337.6 CBY36996.1 - 0.011 14.3 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease AAA_22 PF13401.6 CBY36996.1 - 0.019 15.2 0.0 0.062 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBY36996.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CBY36996.1 - 0.028 14.3 0.0 0.093 12.6 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 CBY36996.1 - 0.036 13.4 0.0 0.088 12.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBY36996.1 - 0.053 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CBY36996.1 - 0.078 12.7 0.0 0.22 11.2 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 CBY36996.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 CBY36996.1 - 0.14 11.7 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY36996.1 - 0.16 11.7 0.1 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBY36996.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sulfatase PF00884.23 CBY36997.1 - 1.3e-48 166.0 0.1 1.6e-48 165.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY36997.1 - 0.00029 20.5 1.7 0.0012 18.5 1.7 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 CBY36997.1 - 0.0033 17.3 0.1 0.03 14.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function bZIP_1 PF00170.21 CBY36998.1 - 6.9e-19 67.7 12.5 6.9e-19 67.7 12.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CBY36998.1 - 2.1e-07 30.9 12.9 3.5e-07 30.2 12.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY36998.1 - 0.004 17.6 4.7 0.0083 16.6 4.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.14 CBY36998.1 - 0.04 14.3 2.1 0.23 11.9 1.7 2.1 2 0 0 2 2 2 0 Nnf1 Rh5 PF18515.1 CBY36998.1 - 0.25 10.6 6.2 0.056 12.7 1.3 2.1 3 0 0 3 3 3 0 Rh5 coiled-coil domain TPR_MLP1_2 PF07926.12 CBY36998.1 - 0.66 10.0 5.6 0.31 11.1 2.6 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BORCS7 PF16088.5 CBY36999.1 - 0.046 14.0 0.4 0.064 13.5 0.4 1.5 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 IRK_C PF17655.1 CBY37000.1 - 1.4e-47 161.6 0.0 1.9e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY37000.1 - 9.5e-34 116.2 7.0 1.3e-33 115.8 7.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 CBY37000.1 - 0.35 10.9 16.3 0.29 11.1 12.9 2.2 1 1 1 2 2 2 0 Ion channel Virul_fac_BrkB PF03631.15 CBY37000.1 - 3.3 7.2 9.9 3.9 7.0 3.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB RCC1 PF00415.18 CBY37001.1 - 7.6e-58 192.9 9.1 4.7e-12 46.3 0.0 8.5 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY37001.1 - 4.3e-24 83.7 41.3 0.00012 21.7 1.2 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ish1 PF10281.9 CBY37003.1 - 0.12 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PPTA PF01239.22 CBY37004.1 - 1.3e-33 113.7 18.8 8e-09 34.9 0.3 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat Spore_III_AB PF09548.10 CBY37004.1 - 0.068 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PPTA PF01239.22 CBY37005.1 - 0.00099 18.8 0.3 0.032 14.0 0.1 2.5 2 0 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat MINDY_DUB PF04424.13 CBY37005.1 - 0.057 13.4 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 MINDY deubiquitinase Amino_oxidase PF01593.24 CBY37005.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase PRANC PF09372.10 CBY37005.1 - 0.38 11.1 2.5 5 7.5 0.4 2.3 1 1 0 2 2 2 0 PRANC domain GDP_Man_Dehyd PF16363.5 CBY37006.1 - 6.5e-35 121.1 0.0 8e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY37006.1 - 4.9e-34 117.8 0.0 5.8e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY37006.1 - 2.7e-16 59.4 0.0 3.3e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBY37006.1 - 4.1e-16 59.0 0.0 5e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY37006.1 - 7.9e-11 42.2 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBY37006.1 - 6.1e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CBY37006.1 - 3.9e-07 29.5 0.0 4.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBY37006.1 - 1e-06 28.2 0.0 1.9e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CBY37006.1 - 1.4e-06 27.9 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CBY37006.1 - 0.00024 20.7 0.0 0.00043 19.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 CBY37006.1 - 0.013 15.7 0.1 0.024 14.9 0.1 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CBY37006.1 - 0.045 13.3 1.3 0.19 11.3 1.3 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4296 PF14129.6 CBY37006.1 - 0.079 13.6 0.7 1.8 9.2 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) DrsE PF02635.15 CBY37006.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 DsrE/DsrF-like family GDP_Man_Dehyd PF16363.5 CBY37007.1 - 5.3e-12 45.8 0.0 6.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY37007.1 - 4.7e-08 32.8 0.0 6.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 CBY37008.1 - 1.2e-32 113.3 32.3 7.1e-31 107.4 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY37008.1 - 0.3 9.9 12.8 47 2.7 12.7 3.1 1 1 0 1 1 1 0 MFS_1 like family DUF4007 PF13182.6 CBY37010.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) TMEM154 PF15102.6 CBY37010.1 - 7.4 6.5 8.1 1.6 8.7 3.5 2.1 2 0 0 2 2 2 0 TMEM154 protein family CutA1 PF03091.15 CBY37011.1 - 7.6e-37 125.2 0.0 8.5e-37 125.0 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein FapA PF03961.13 CBY37012.1 - 0.0022 16.7 5.1 0.0043 15.7 5.1 1.4 1 0 0 1 1 1 1 Flagellar Assembly Protein A Adaptin_binding PF10199.9 CBY37012.1 - 0.0055 17.3 0.0 0.0092 16.6 0.0 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Imm64 PF15600.6 CBY37012.1 - 0.044 13.4 1.4 0.077 12.7 1.4 1.3 1 0 0 1 1 1 0 Immunity protein 64 DUF4446 PF14584.6 CBY37012.1 - 0.07 13.1 8.6 0.9 9.5 6.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Syntaxin_2 PF14523.6 CBY37012.1 - 0.41 11.0 8.0 0.12 12.8 4.9 1.7 2 0 0 2 2 2 0 Syntaxin-like protein GAS PF13851.6 CBY37012.1 - 0.43 9.9 15.3 0.035 13.5 10.6 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Synaptobrevin PF00957.21 CBY37012.1 - 0.73 9.7 13.0 0.22 11.3 9.1 2.0 2 0 0 2 2 2 0 Synaptobrevin Fib_alpha PF08702.10 CBY37012.1 - 1.6 8.9 10.4 0.31 11.2 6.8 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CBY37012.1 - 2.7 8.0 7.8 3.3 7.8 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2681 PF10883.8 CBY37012.1 - 6 7.4 9.5 1.5 9.3 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Val_tRNA-synt_C PF10458.9 CBY37012.1 - 9.4 6.6 10.9 1.6 9.1 6.3 2.2 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm EF-hand_7 PF13499.6 CBY37014.1 - 4.3e-12 46.3 2.7 5.9e-06 26.6 0.3 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY37014.1 - 1.3e-11 43.5 0.5 9.4e-06 25.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY37014.1 - 5.3e-10 38.1 1.3 7.7e-05 22.0 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBY37014.1 - 5.1e-06 25.7 0.7 0.021 14.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY37014.1 - 0.0044 16.8 0.8 3.6 7.5 0.3 3.4 2 1 2 4 4 4 2 EF-hand domain pair RST PF12174.8 CBY37014.1 - 0.013 15.4 0.5 0.032 14.1 0.2 1.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain SPARC_Ca_bdg PF10591.9 CBY37014.1 - 0.013 15.8 0.6 2.6 8.4 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CBY37014.1 - 0.038 14.3 0.0 0.3 11.5 0.0 2.4 3 1 0 3 3 3 0 EF-hand domain Rap_GAP PF02145.15 CBY37015.1 - 0.0006 19.4 0.0 0.39 10.2 0.0 3.2 3 0 0 3 3 3 2 Rap/ran-GAP EMP70 PF02990.16 CBY37016.1 - 1.2e-104 350.9 0.0 1.3e-104 350.7 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.6 CBY37016.1 - 1.5 9.0 6.4 4 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF4083 PF13314.6 CBY37016.1 - 2.6 8.1 4.8 0.6 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Pkinase PF00069.25 CBY37019.1 - 4.3e-33 114.8 0.0 6.8e-33 114.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY37019.1 - 5.3e-08 32.5 0.0 8.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CBY37019.1 - 5.6e-07 29.1 0.0 7.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY37019.1 - 7.8e-05 22.7 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY37019.1 - 0.002 17.7 0.1 0.0034 17.0 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY37019.1 - 0.0022 17.4 0.0 0.0058 16.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY37019.1 - 0.0062 15.4 0.0 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY37019.1 - 0.012 14.6 0.1 0.64 8.9 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Ion_trans PF00520.31 CBY37022.1 - 1.2e-05 24.7 4.9 1.7e-05 24.2 4.9 1.2 1 0 0 1 1 1 1 Ion transport protein CENP-B_dimeris PF09026.10 CBY37022.1 - 0.02 15.3 0.5 0.03 14.7 0.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adeno_shaft PF00608.17 CBY37022.1 - 0.085 12.7 0.2 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) Ion_trans PF00520.31 CBY37024.1 - 1.1e-05 24.9 4.8 1.5e-05 24.3 4.8 1.2 1 0 0 1 1 1 1 Ion transport protein CENP-B_dimeris PF09026.10 CBY37024.1 - 0.02 15.3 0.5 0.03 14.7 0.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Adeno_shaft PF00608.17 CBY37024.1 - 0.084 12.7 0.2 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Adenoviral fibre protein (repeat/shaft region) Ion_trans PF00520.31 CBY37025.1 - 5.7e-13 48.7 16.8 7.5e-13 48.3 16.8 1.1 1 0 0 1 1 1 1 Ion transport protein Mito_carr PF00153.27 CBY37026.1 - 3.6e-50 167.9 0.6 1.8e-22 79.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S10 PF00338.22 CBY37028.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.9 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e UbiA PF01040.18 CBY37029.1 - 4.2e-18 65.6 0.1 6.1e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 CBY37030.1 - 9.4e-06 25.1 6.7 0.00069 19.0 6.9 2.4 1 1 0 1 1 1 1 UbiA prenyltransferase family LSM PF01423.22 CBY37031.1 - 4.8e-21 74.2 1.0 5.4e-21 74.0 1.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY37031.1 - 0.083 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CBY37031.1 - 0.083 13.0 0.2 0.12 12.4 0.2 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain HORMA PF02301.18 CBY37034.1 - 2.4e-21 76.3 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Tenui_PVC2 PF06656.11 CBY37036.1 - 1 7.1 4.3 1.5 6.7 4.3 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein C1q PF00386.21 CBY37037.1 - 8.4e-17 61.6 1.5 1.5e-16 60.8 1.5 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CBY37037.1 - 0.0016 18.1 6.1 0.0027 17.4 6.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TNF PF00229.18 CBY37037.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Tubulin PF00091.25 CBY37038.1 - 2.8e-66 223.5 0.0 4.2e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY37038.1 - 5.5e-51 172.0 0.0 1.1e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY37038.1 - 0.0012 18.6 0.0 0.0046 16.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Somatomedin_B PF01033.17 CBY37039.1 - 0.00028 21.2 13.7 0.00028 21.2 13.7 2.4 2 0 0 2 2 2 1 Somatomedin B domain SMYLE_N PF18615.1 CBY37039.1 - 0.012 15.2 9.4 0.018 14.6 9.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CTXphi_pIII-N1 PF16710.5 CBY37039.1 - 0.037 14.2 0.4 0.21 11.7 0.4 2.3 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII DUF5521 PF17659.1 CBY37039.1 - 0.6 7.9 7.2 0.83 7.4 7.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Glyco_hydro_47 PF01532.20 CBY37040.1 - 3.5e-88 296.5 0.0 1.2e-87 294.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 CBY37040.1 - 4.2e-09 36.3 0.0 8.3e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Meckelin PF09773.9 CBY37041.1 - 2.3e-235 783.5 10.7 2.3e-235 783.5 10.7 1.7 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) EGF_MSP1_1 PF12946.7 CBY37041.1 - 0.099 12.7 2.0 0.24 11.5 2.0 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 BaffR-Tall_bind PF09256.10 CBY37041.1 - 0.92 9.3 6.1 0.36 10.6 2.1 2.4 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding DUF3502 PF12010.8 CBY37042.1 - 0.04 14.5 0.8 0.07 13.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) DAO PF01266.24 CBY37043.1 - 3.7e-60 204.4 0.0 6e-60 203.7 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 CBY37043.1 - 1.3e-05 24.0 0.0 0.088 11.3 0.0 2.3 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 CBY37043.1 - 2.1e-05 23.9 0.2 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBY37043.1 - 0.0018 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CBY37043.1 - 0.004 16.4 0.0 0.82 8.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CBY37043.1 - 0.0064 16.7 0.1 0.019 15.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CBY37043.1 - 0.096 11.7 0.4 0.55 9.2 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 CBY37043.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CBY37043.1 - 0.21 11.6 0.2 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding WD40_like PF17005.5 CBY37044.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 CBY37044.1 - 0.024 14.9 0.3 0.12 12.7 0.0 2.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4097 PF13349.6 CBY37044.1 - 0.033 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative adhesin Ig_3 PF13927.6 CBY37045.1 - 2.6e-15 56.8 0.0 3.8e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY37045.1 - 2.4e-12 46.7 0.0 1.2e-09 38.1 0.0 2.4 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY37045.1 - 9.7e-11 41.9 0.1 5.2e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CBY37045.1 - 1.8e-07 31.2 0.1 9.1e-07 29.0 0.0 2.1 2 1 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 CBY37045.1 - 3.4e-07 30.4 4.6 8.4e-07 29.1 4.6 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain C2-set_2 PF08205.12 CBY37045.1 - 3.1e-05 24.0 0.1 0.004 17.2 0.0 2.5 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CBY37045.1 - 0.053 13.9 0.0 3 8.3 0.1 2.4 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PKD_3 PF16820.5 CBY37045.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain TSP_1 PF00090.19 CBY37047.1 - 0.0027 17.9 5.9 0.0027 17.9 5.9 3.4 2 2 0 2 2 2 1 Thrombospondin type 1 domain Raf1_HTH PF18579.1 CBY37047.1 - 0.39 10.5 1.8 8.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain 2OG-FeII_Oxy_3 PF13640.6 CBY37048.1 - 0.069 14.0 0.0 0.16 12.9 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 CBY37051.1 - 2.3e-38 132.1 0.0 8.8e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY37051.1 - 6.8e-37 125.4 0.1 3e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY37051.1 - 1.7e-11 43.9 0.0 5.5e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBY37051.1 - 0.019 14.0 0.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Phage_GP20 PF06810.11 CBY37051.1 - 0.019 14.7 29.7 0.069 12.9 10.7 3.3 2 1 0 3 3 3 0 Phage minor structural protein GP20 T3SS_needle_E PF08988.10 CBY37051.1 - 0.029 14.5 5.1 0.85 9.8 1.1 3.1 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF3584 PF12128.8 CBY37051.1 - 0.043 11.4 12.2 0.068 10.7 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APH PF01636.23 CBY37051.1 - 0.057 13.3 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.29 CBY37051.1 - 0.057 13.2 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase Csm1_N PF18504.1 CBY37051.1 - 0.084 13.2 15.2 0.24 11.8 2.6 3.4 3 0 0 3 3 3 0 Csm1 N-terminal domain PKcGMP_CC PF16808.5 CBY37051.1 - 0.11 12.4 13.0 1 9.3 0.4 3.9 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RRF_GI PF12614.8 CBY37051.1 - 0.19 11.9 2.4 0.49 10.6 2.4 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Rpn9_C PF18261.1 CBY37051.1 - 0.32 10.6 2.0 1.2 8.8 0.6 2.5 2 0 0 2 2 2 0 Rpn9 C-terminal helix Med4 PF10018.9 CBY37051.1 - 0.65 9.6 12.5 0.11 12.2 2.2 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4407 PF14362.6 CBY37051.1 - 1.6 8.0 6.5 3 7.1 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4208 PF13907.6 CBY37051.1 - 1.6 9.2 4.6 1.3 9.5 2.1 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4208) Baculo_PEP_C PF04513.12 CBY37051.1 - 1.8 8.6 6.5 12 6.0 4.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CBY37051.1 - 2.8 7.5 7.4 2.5 7.6 5.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 CBY37051.1 - 2.8 7.3 16.6 0.42 10.0 12.4 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 HalX PF08663.10 CBY37051.1 - 3.8 7.9 9.0 1.6 9.1 0.7 3.1 3 0 0 3 3 3 0 HalX domain UPF0242 PF06785.11 CBY37051.1 - 4.3 7.4 17.3 0.97 9.5 12.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlgN PF05130.12 CBY37051.1 - 5.5 7.5 15.0 0.084 13.4 4.6 2.8 2 1 1 3 3 3 0 FlgN protein FliJ PF02050.16 CBY37051.1 - 9.9 6.4 15.5 0.42 10.8 8.3 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Med3 PF11593.8 CBY37053.1 - 0.048 12.9 4.6 0.082 12.1 4.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HU-CCDC81_euk_1 PF14908.6 CBY37053.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 LZ_Tnp_IS66 PF13007.7 CBY37053.1 - 1.3 9.9 4.9 0.4 11.5 1.9 1.7 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Hydrolase_4 PF12146.8 CBY37055.1 - 1.8e-30 106.0 0.0 2.8e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY37055.1 - 8.9e-06 25.5 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY37055.1 - 8.7e-05 23.2 0.0 0.00012 22.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CBY37055.1 - 0.016 15.1 0.0 0.16 11.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CBY37055.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 CBY37055.1 - 0.054 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.7 CBY37055.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TcpE PF12648.7 CBY37056.1 - 0.077 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 TcpE family 7tm_1 PF00001.21 CBY37057.1 - 1.6e-39 135.8 16.2 2.2e-39 135.4 16.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY37057.1 - 1.7e-06 27.9 22.1 1.7e-06 27.9 22.1 2.1 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srx 7tm_4 PF13853.6 CBY37057.1 - 0.0018 18.1 14.4 0.0056 16.4 9.7 2.2 2 0 0 2 2 2 2 Olfactory receptor BioY PF02632.14 CBY37057.1 - 0.21 11.6 4.1 0.35 10.9 2.9 1.9 1 1 1 2 2 2 0 BioY family DUF1700 PF08006.11 CBY37058.1 - 0.091 12.3 1.2 0.16 11.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Myosin_head PF00063.21 CBY37060.1 - 2.7e-208 693.5 6.6 3e-208 693.3 6.6 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CBY37060.1 - 0.014 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 CBY37060.1 - 0.026 14.3 1.1 0.079 12.8 1.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_10 PF12846.7 CBY37060.1 - 0.047 12.6 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 CBY37060.1 - 0.048 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CBY37060.1 - 0.059 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 CBY37060.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBY37060.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phospholip_A2_1 PF00068.19 CBY37061.1 - 5.5e-17 62.3 11.2 9.9e-17 61.4 11.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 DUF3752 PF12572.8 CBY37063.1 - 9.6e-14 52.2 15.2 9.6e-14 52.2 15.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) CDC27 PF09507.10 CBY37064.1 - 1.9 7.8 14.1 2.8 7.2 14.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_1 PF00036.32 CBY37065.1 - 6.2e-21 72.3 7.0 0.0006 19.2 0.3 5.9 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 CBY37065.1 - 1e-17 62.7 5.3 0.00052 19.4 0.0 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY37065.1 - 1.7e-15 55.6 9.3 0.029 14.3 0.0 5.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY37065.1 - 1.9e-15 57.1 19.2 1e-09 38.7 0.5 3.6 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CBY37065.1 - 5.2e-07 29.4 18.3 0.033 14.0 0.0 5.3 5 1 1 6 6 6 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY37065.1 - 0.0014 19.0 12.9 0.0022 18.3 0.4 3.4 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBY37065.1 - 0.49 10.3 4.1 10 6.1 0.3 3.5 3 0 0 3 3 3 0 EF hand Dockerin_1 PF00404.18 CBY37065.1 - 1.5 9.0 5.0 5.5 7.3 0.1 3.5 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_4 PF12763.7 CBY37065.1 - 4.3 7.3 13.1 2.6 8.1 0.2 3.8 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Abhydrolase_2 PF02230.16 CBY37066.1 - 3.9e-56 190.3 0.0 4.4e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY37066.1 - 1.8e-09 37.2 0.0 0.00015 21.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CBY37066.1 - 4.3e-07 29.6 0.1 0.033 13.7 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 CBY37066.1 - 2.7e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBY37066.1 - 5.1e-06 26.3 0.0 2.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY37066.1 - 5.6e-06 27.1 0.0 7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CBY37066.1 - 6.9e-06 25.9 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CBY37066.1 - 1.5e-05 24.8 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CBY37066.1 - 0.0035 17.2 0.0 0.031 14.1 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 CBY37066.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 CBY37066.1 - 0.024 13.6 0.0 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydro_lipase PF04083.16 CBY37066.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region RhoGAP PF00620.27 CBY37068.1 - 7.9e-10 38.8 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Delta_lysin PF05372.11 CBY37068.1 - 0.033 13.5 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 Delta lysin family DUF3899 PF13038.6 CBY37069.1 - 0.08 13.5 0.3 3.4 8.2 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) KASH PF10541.9 CBY37069.1 - 0.2 11.9 1.7 0.24 11.7 0.3 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain Pkinase PF00069.25 CBY37070.1 - 1.5e-08 34.3 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37070.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Scramblase PF03803.15 CBY37071.1 - 1.2e-80 270.0 0.2 1.4e-80 269.7 0.2 1.0 1 0 0 1 1 1 1 Scramblase ITI_HC_C PF06668.12 CBY37072.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus DUF5365 PF17326.2 CBY37073.1 - 0.019 15.4 0.7 0.046 14.1 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5365) Rad60-SLD PF11976.8 CBY37073.1 - 0.059 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Syntaxin_2 PF14523.6 CBY37073.1 - 0.077 13.4 2.4 0.19 12.1 0.3 2.4 2 1 1 3 3 3 0 Syntaxin-like protein Innexin PF00876.18 CBY37074.1 - 0.0055 16.0 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Innexin RRM_1 PF00076.22 CBY37075.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY37075.1 - 4.9e-05 23.2 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CBY37075.1 - 0.0004 20.4 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RNA_bind PF08675.11 CBY37075.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Tubulin_C PF03953.17 CBY37076.1 - 5e-18 65.5 0.0 7.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CBY37076.1 - 9.9e-06 25.9 0.0 1.5e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FYVE PF01363.21 CBY37077.1 - 7.1e-18 64.5 13.2 1.9e-17 63.2 13.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger CENP-F_leu_zip PF10473.9 CBY37077.1 - 0.0017 18.4 13.1 0.0017 18.4 13.1 4.7 2 2 2 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CBY37077.1 - 0.0034 17.4 46.9 0.21 11.6 1.6 6.0 1 1 3 6 6 6 4 Protein of unknown function (DUF1664) ATG16 PF08614.11 CBY37077.1 - 0.005 17.1 78.2 0.054 13.7 24.4 4.6 2 2 2 4 4 4 3 Autophagy protein 16 (ATG16) ERM PF00769.19 CBY37077.1 - 0.0072 16.2 90.4 0.16 11.8 20.6 4.1 2 2 2 4 4 4 3 Ezrin/radixin/moesin family BRE1 PF08647.11 CBY37077.1 - 0.014 15.5 10.0 0.014 15.5 10.0 7.2 2 2 4 6 6 4 0 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 CBY37077.1 - 0.022 12.3 67.5 0.14 9.6 7.0 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) PspA_IM30 PF04012.12 CBY37077.1 - 0.072 12.7 56.0 1.4 8.4 21.7 4.7 2 2 0 3 3 3 0 PspA/IM30 family Filament PF00038.21 CBY37077.1 - 0.076 12.6 70.7 0.0082 15.8 29.9 4.0 2 1 2 4 4 4 0 Intermediate filament protein RNA_POL_M_15KD PF02150.16 CBY37077.1 - 0.4 10.6 11.2 3.1 7.8 1.2 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 CBY37077.1 - 0.45 10.7 10.4 30 4.9 2.0 2.9 1 1 1 2 2 2 0 Zinc ribbon domain IBR PF01485.21 CBY37077.1 - 0.78 10.0 9.9 0.15 12.3 5.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF812 PF05667.11 CBY37077.1 - 2.4 7.0 75.5 0.099 11.5 35.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 CBY37077.1 - 3.8 7.2 74.6 1.7 8.3 10.1 5.9 2 2 3 5 5 5 0 Domain of unknown function (DUF4201) MUG113 PF13455.6 CBY37077.1 - 6.2 7.6 6.8 1.7 9.3 0.2 3.3 3 0 0 3 3 3 0 Meiotically up-regulated gene 113 Fez1 PF06818.15 CBY37077.1 - 9.4 6.6 77.1 1.8 8.9 19.9 4.3 1 1 2 4 4 4 0 Fez1 TPR_MLP1_2 PF07926.12 CBY37077.1 - 9.6 6.3 90.2 0.065 13.3 6.6 6.1 2 2 5 7 7 6 0 TPR/MLP1/MLP2-like protein LSM PF01423.22 CBY37078.1 - 2.8e-14 52.6 0.1 4.9e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 LSM domain BRD4_CDT PF17105.5 CBY37078.1 - 0.16 11.6 3.5 0.27 10.9 3.5 1.3 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Ribosomal_S26e PF01283.19 CBY37079.1 - 6.1e-50 168.2 9.2 7e-50 168.0 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e NPV_P10 PF05531.12 CBY37080.1 - 0.037 14.5 0.8 0.13 12.7 0.3 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PP_kinase_C_1 PF17941.1 CBY37080.1 - 0.058 12.9 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 S10_plectin PF03501.15 CBY37081.1 - 1.3e-39 134.1 0.1 1.6e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain BLACT_WH PF17778.1 CBY37082.1 - 2.2e-07 30.7 0.1 4.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 CBY37082.1 - 2.8e-05 24.2 0.0 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF4042 PF13251.6 CBY37083.1 - 6.9e-18 65.0 4.3 1.8e-17 63.6 1.7 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT PF02985.22 CBY37083.1 - 0.0023 18.0 2.6 1.6 9.2 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat zf-C3HC4_3 PF13920.6 CBY37085.1 - 0.49 10.3 20.4 4.2 7.3 0.7 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.19 CBY37086.1 - 1.3e-66 224.9 0.0 2.5e-65 220.7 0.0 1.9 1 1 0 1 1 1 1 Actin Cnd2 PF05786.14 CBY37087.1 - 1.9e-30 106.3 33.2 1.7e-29 103.1 33.2 2.3 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CBY37087.1 - 6.8e-06 26.3 0.9 6.8e-06 26.3 0.9 3.1 2 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal ALG3 PF05208.13 CBY37088.1 - 1.8e-52 179.0 2.3 2e-52 178.8 2.3 1.0 1 0 0 1 1 1 1 ALG3 protein MAP17 PF15807.5 CBY37088.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2644 PF10841.8 CBY37088.1 - 0.39 11.0 2.1 0.45 10.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) DUF3456 PF11938.8 CBY37090.1 - 1.9e-06 28.5 7.7 0.00075 20.1 0.3 2.8 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 CBY37090.1 - 0.00027 21.3 16.1 0.00027 21.3 16.1 3.8 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.24 CBY37090.1 - 0.016 15.4 13.5 0.016 15.4 13.5 4.5 2 1 2 4 4 4 0 Laminin EGF domain Ras PF00071.22 CBY37091.1 - 2.7e-55 186.4 0.0 3.2e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37091.1 - 4.2e-33 114.1 0.0 5.9e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37091.1 - 3.4e-12 46.1 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY37091.1 - 6.1e-07 29.5 0.0 9.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY37091.1 - 0.00015 21.7 0.1 0.005 16.7 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CBY37091.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBY37091.1 - 0.00044 19.9 0.0 0.017 14.7 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CBY37091.1 - 0.0016 18.2 0.1 0.086 12.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY37091.1 - 0.0045 16.6 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBY37091.1 - 0.0075 16.5 0.1 0.026 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY37091.1 - 0.014 15.7 0.1 0.018 15.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CBY37091.1 - 0.016 14.5 0.1 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 CBY37091.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CBY37091.1 - 0.017 14.5 0.1 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CBY37091.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY37091.1 - 0.024 14.1 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CBY37091.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 CBY37091.1 - 0.044 13.7 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CBY37091.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_75 PF07335.11 CBY37091.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 CBY37091.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CBY37091.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 CBY37091.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 CBY37091.1 - 0.2 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2870 PF11069.8 CBY37092.1 - 8.6e-41 138.2 1.7 1.7e-40 137.3 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) PSP1 PF04468.12 CBY37092.1 - 0.04 14.2 0.5 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 PSP1 C-terminal conserved region ubiquitin PF00240.23 CBY37092.1 - 0.13 12.0 0.2 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family GCH_III PF05165.12 CBY37093.1 - 0.028 13.7 0.2 0.034 13.4 0.2 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III Sds3 PF08598.11 CBY37093.1 - 0.037 14.0 0.8 0.037 14.0 0.8 1.5 2 0 0 2 2 2 0 Sds3-like DUF1690 PF07956.11 CBY37093.1 - 0.12 12.8 12.2 1 9.8 12.2 2.1 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4600 PF15372.6 CBY37093.1 - 0.15 12.5 7.0 0.062 13.7 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF1664 PF07889.12 CBY37093.1 - 0.27 11.3 1.7 0.5 10.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF349 PF03993.12 CBY37093.1 - 1.3 9.4 13.8 0.68 10.3 2.4 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Remorin_C PF03763.13 CBY37093.1 - 1.8 8.5 9.3 0.37 10.7 5.8 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region Cep57_CLD PF14073.6 CBY37094.1 - 8.6e-08 32.4 23.2 8.6e-08 32.4 23.2 3.8 2 2 0 2 2 2 1 Centrosome localisation domain of Cep57 Ras PF00071.22 CBY37095.1 - 3.1e-25 88.7 0.0 3.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37095.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY37095.1 - 0.00041 20.4 0.0 0.0007 19.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.9 CBY37095.1 - 0.0015 17.7 0.1 0.34 10.0 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 CBY37095.1 - 0.068 12.6 0.0 0.99 8.8 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Orbi_NS3 PF01616.16 CBY37095.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 Flavin_Reduct PF01613.18 CBY37095.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Flavin reductase like domain Mon1 PF03164.14 CBY37095.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 HECT PF00632.25 CBY37096.1 - 9.1e-86 288.1 0.0 1.2e-85 287.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C2 PF00168.30 CBY37096.1 - 8.8e-18 64.5 0.1 1.6e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 C2 domain WW PF00397.26 CBY37096.1 - 8.9e-09 35.3 2.9 1.6e-08 34.5 2.9 1.5 1 0 0 1 1 1 1 WW domain DMAP1 PF05499.12 CBY37097.1 - 8.6e-26 90.8 2.2 2e-25 89.6 2.2 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CBY37097.1 - 1.2e-18 67.1 0.6 2.6e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ntox1 PF15500.6 CBY37097.1 - 0.011 16.1 1.4 0.022 15.1 1.4 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 CP2 PF04516.15 CBY37099.1 - 9.5e-50 169.0 0.4 1.5e-49 168.4 0.4 1.2 1 0 0 1 1 1 1 CP2 transcription factor EF-hand_13 PF17958.1 CBY37100.1 - 4.3e-26 90.5 0.0 4.7e-25 87.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY37100.1 - 4.9e-14 52.5 0.5 1.4e-13 51.1 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY37100.1 - 0.00069 19.0 0.3 0.002 17.5 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY37100.1 - 0.0018 18.0 0.2 0.013 15.4 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY37100.1 - 0.01 15.3 0.4 0.01 15.3 0.4 2.4 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBY37100.1 - 0.17 11.7 0.3 0.54 10.2 0.3 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF5633 PF18656.1 CBY37102.1 - 0.57 10.1 2.9 1.7 8.6 2.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5633) GTP_EFTU PF00009.27 CBY37103.1 - 0.00034 20.2 0.0 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CBY37103.1 - 0.00059 19.1 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBY37103.1 - 0.00087 19.4 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CBY37103.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CBY37103.1 - 0.0087 16.0 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBY37103.1 - 0.0088 16.4 0.0 0.025 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 CBY37103.1 - 0.013 14.8 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 CBY37103.1 - 0.016 14.9 0.0 0.071 12.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 CBY37103.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 CBY37103.1 - 0.019 14.5 0.8 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CBY37103.1 - 0.044 14.3 0.1 0.12 12.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY37103.1 - 0.048 13.7 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.10 CBY37103.1 - 0.052 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 CBY37103.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 CBY37103.1 - 0.15 12.2 0.6 2.9 8.1 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY37104.1 - 8.5e-60 201.0 0.2 9.9e-60 200.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37104.1 - 3e-35 121.1 0.1 5.4e-35 120.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37104.1 - 2.2e-12 46.8 0.1 2.7e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY37104.1 - 4.9e-05 23.4 0.0 0.0001 22.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY37104.1 - 0.00024 20.5 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBY37104.1 - 0.00046 20.1 0.2 0.36 10.7 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY37104.1 - 0.00068 19.2 0.1 0.0015 18.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBY37104.1 - 0.013 15.9 0.8 0.048 14.1 0.8 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ribosomal_L30_N PF08079.12 CBY37104.1 - 0.22 11.8 2.4 5 7.4 0.0 2.3 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain Lectin_C PF00059.21 CBY37108.1 - 3.1e-47 159.8 21.8 1.6e-13 51.4 3.1 4.3 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 CBY37108.1 - 0.04 13.6 9.4 7 6.2 0.1 4.0 4 0 0 4 4 4 0 UL45 protein, carbohydrate-binding C-type lectin-like Trefoil PF00088.18 CBY37108.1 - 0.12 12.3 9.0 0.13 12.2 6.6 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain Trypsin PF00089.26 CBY37109.1 - 1.7e-67 227.5 4.7 2.7e-34 118.9 0.1 2.1 2 0 0 2 2 2 2 Trypsin DUF1986 PF09342.11 CBY37109.1 - 8.7e-10 39.0 0.6 4.3e-06 27.1 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Chromo PF00385.24 CBY37110.1 - 5.6e-30 103.0 4.3 4.4e-11 42.5 0.1 3.8 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY37110.1 - 0.0016 18.2 4.8 0.016 15.1 0.1 2.9 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain DUF1918 PF08940.11 CBY37110.1 - 0.062 12.9 0.8 6.2 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) DDHD PF02862.17 CBY37110.1 - 3.8 7.6 13.7 0.44 10.7 5.7 2.3 2 1 0 2 2 2 0 DDHD domain GARS_C PF02843.16 CBY37111.1 - 0.22 11.8 14.5 1.2 9.4 0.7 4.3 1 1 1 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Nebulin PF00880.18 CBY37113.1 - 3.4e-17 62.0 75.2 2.5e-05 24.1 3.4 11.4 11 0 0 11 11 11 9 Nebulin repeat DUF2256 PF10013.9 CBY37114.1 - 0.09 12.9 0.9 0.14 12.3 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Phasin PF05597.11 CBY37115.1 - 0.0093 16.0 3.0 0.0093 16.0 3.0 2.2 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Mu-like_Pro PF10123.9 CBY37115.1 - 0.029 13.9 0.8 0.033 13.7 0.8 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein HSCB_C PF07743.13 CBY37115.1 - 0.1 13.1 11.2 0.78 10.3 5.2 2.7 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Med4 PF10018.9 CBY37115.1 - 1.1 8.9 9.2 0.064 12.9 2.1 2.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc24 PF08286.11 CBY37115.1 - 1.4 9.2 11.7 2.5 8.4 0.8 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 CBY37115.1 - 1.4 9.3 8.1 2.5 8.6 0.9 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 CBY37115.1 - 6.1 7.1 10.2 11 6.3 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Zona_pellucida PF00100.23 CBY37116.1 - 1.1e-07 31.9 0.3 1.3e-07 31.7 0.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Trefoil PF00088.18 CBY37117.1 - 1.4e-19 69.7 8.7 1.4e-10 40.9 1.7 2.3 2 0 0 2 2 2 2 Trefoil (P-type) domain NAAA-beta PF15508.6 CBY37118.1 - 0.091 13.1 0.3 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Endonuclease_NS PF01223.23 CBY37123.1 - 4.2e-25 88.9 5.4 1.5e-24 87.0 5.4 1.7 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBY37123.1 - 0.014 15.5 0.2 0.032 14.4 0.2 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DUF4762 PF15959.5 CBY37123.1 - 0.029 14.3 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) Ceramidase PF05875.12 CBY37123.1 - 0.049 13.0 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Ceramidase Pox_F15 PF04596.12 CBY37123.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus protein F15 O-FucT PF10250.9 CBY37124.1 - 0.0013 18.5 0.3 0.0038 17.0 0.3 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_M3 PF01432.20 CBY37128.1 - 0.13 11.5 0.2 0.8 8.9 0.1 2.0 1 1 1 2 2 2 0 Peptidase family M3 DUF4682 PF15733.5 CBY37128.1 - 0.45 11.1 7.3 0.69 10.5 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) PHC2_SAM_assoc PF16616.5 CBY37129.1 - 0.17 12.7 8.2 0.24 12.2 8.2 1.4 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Dicty_REP PF05086.12 CBY37129.1 - 0.89 7.5 4.8 0.84 7.5 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M41 PF01434.18 CBY37130.1 - 8.4e-29 100.8 0.1 1.1e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M41 CNH PF00780.22 CBY37130.1 - 4.7e-18 65.8 0.0 6.1e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 CNH domain NDK PF00334.19 CBY37133.1 - 3.3e-96 318.5 0.3 6.5e-32 110.4 0.0 3.2 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 CBY37133.1 - 7.2e-06 25.9 0.0 2.1e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.21 CBY37133.1 - 0.01 15.6 1.2 1.3 8.8 0.1 3.4 3 0 0 3 3 3 0 Arginine repressor, DNA binding domain IlvN PF07991.12 CBY37133.1 - 0.021 14.4 0.4 0.78 9.3 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pkinase_Tyr PF07714.17 CBY37136.1 - 1.4e-66 224.4 0.0 1.6e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY37136.1 - 4.6e-32 111.4 0.0 6.1e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CBY37136.1 - 4.4e-06 26.2 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBY37136.1 - 0.00077 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY37136.1 - 0.024 14.5 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Swi3 PF07962.12 CBY37136.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.0 3 0 0 3 3 3 0 Replication Fork Protection Component Swi3 HR1 PF02185.16 CBY37137.1 - 0.017 15.2 0.2 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat TIG PF01833.24 CBY37138.1 - 9.2e-43 144.2 43.8 7.5e-11 42.0 3.2 9.0 7 1 1 8 8 8 7 IPT/TIG domain G8 PF10162.9 CBY37138.1 - 9.3e-33 112.9 0.0 2.3e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 G8 domain Kringle PF00051.18 CBY37138.1 - 0.067 13.5 7.0 0.25 11.7 7.0 2.1 1 0 0 1 1 1 0 Kringle domain E1-E2_ATPase PF00122.20 CBY37139.1 - 1e-33 116.4 10.0 5.2e-25 88.0 0.9 2.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 CBY37139.1 - 4.3e-12 45.5 0.0 9.2e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Oxidored_q3 PF00499.20 CBY37139.1 - 0.0075 16.0 1.3 0.29 10.8 0.7 2.2 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pox_A14 PF05767.12 CBY37139.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.2 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 Glyco_transf_49 PF13896.6 CBY37140.1 - 1.9e-31 109.7 4.0 2.5e-31 109.3 4.0 1.0 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan OpuAC PF04069.12 CBY37140.1 - 0.13 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system DEAD PF00270.29 CBY37141.1 - 3.6e-51 173.4 0.0 4.8e-50 169.7 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY37141.1 - 1.7e-30 105.6 0.1 6.4e-29 100.5 0.2 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY37141.1 - 0.00012 22.1 0.0 0.00035 20.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY37141.1 - 0.00014 21.2 0.8 0.00018 20.8 0.1 1.4 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 CBY37141.1 - 0.034 12.9 0.0 0.093 11.5 0.0 1.7 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CBY37141.1 - 0.2 11.9 0.1 0.82 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 CBY37143.1 - 1.7e-40 137.3 0.5 2.8e-40 136.6 0.5 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBY37143.1 - 5.2e-23 80.9 0.1 9.2e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBY37143.1 - 2.7e-18 66.1 0.0 5.2e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY37143.1 - 1.1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 CBY37143.1 - 0.06 13.9 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 CBY37143.1 - 0.08 11.9 0.2 0.21 10.5 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SafA PF17073.5 CBY37143.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Two-component-system connector protein bZIP_Maf PF03131.17 CBY37144.1 - 4.4e-16 59.2 3.0 5.9e-16 58.8 3.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 CBY37144.1 - 2.2 8.4 11.6 4.1 7.6 11.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor TPX2 PF06886.11 CBY37146.1 - 4.1e-07 30.1 9.9 4.1e-07 30.1 9.9 2.8 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) Importin_rep_4 PF18808.1 CBY37147.1 - 2.5e-13 50.1 0.4 8.7e-13 48.4 0.4 1.9 1 0 0 1 1 1 1 Importin repeat HEAT_2 PF13646.6 CBY37147.1 - 0.00032 21.0 0.2 9.2 6.7 0.0 4.0 3 2 0 3 3 3 2 HEAT repeats IBN_N PF03810.19 CBY37147.1 - 0.00063 19.6 0.1 0.0062 16.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 CBY37147.1 - 0.0048 16.7 0.2 0.11 12.2 0.0 2.5 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF3921 PF13060.6 CBY37148.1 - 0.0056 16.7 0.9 0.68 10.0 0.2 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3921) DUF2559 PF10832.8 CBY37148.1 - 0.14 12.3 4.2 4.5 7.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) DUF5398 PF17376.2 CBY37148.1 - 0.15 12.7 0.5 0.15 12.7 0.5 3.7 3 1 1 4 4 4 0 Family of unknown function (DUF5398) ApoO PF09769.9 CBY37148.1 - 0.19 11.7 9.9 1.3 9.0 0.1 3.9 3 2 1 4 4 4 0 Apolipoprotein O CEP209_CC5 PF16574.5 CBY37148.1 - 0.33 11.1 25.7 0.15 12.2 14.2 2.8 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 OmpH PF03938.14 CBY37148.1 - 1.2 9.5 49.2 3.4 8.0 8.6 3.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Dict-STAT-coil PF09267.10 CBY37148.1 - 1.5 9.2 13.7 0.073 13.5 3.3 3.2 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil Filament PF00038.21 CBY37148.1 - 3.6 7.1 44.4 9 5.8 35.6 3.2 1 1 1 2 2 2 0 Intermediate filament protein VPS11_C PF12451.8 CBY37148.1 - 7.7 6.8 8.5 37 4.6 1.0 3.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF948 PF06103.11 CBY37148.1 - 9.2 6.6 22.0 3 8.2 1.8 5.2 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Trypsin PF00089.26 CBY37149.1 - 4.7e-38 131.2 0.0 5.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY37149.1 - 0.0016 19.3 0.0 0.0031 18.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY37149.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) CLZ PF16526.5 CBY37150.1 - 0.0081 16.5 0.7 0.013 15.8 0.7 1.3 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels betaPIX_CC PF16523.5 CBY37150.1 - 0.019 14.8 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Ion_trans PF00520.31 CBY37151.1 - 4.7e-20 71.9 20.1 8.3e-20 71.0 20.1 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY37151.1 - 4.1e-09 36.3 2.1 4.1e-09 36.3 2.1 2.2 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 CBY37151.1 - 2.5e-07 30.7 0.0 5.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Zemlya PF17646.1 CBY37151.1 - 0.012 15.9 0.2 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 Closterovirus 1a polyprotein central region DUF2894 PF11445.8 CBY37151.1 - 0.057 13.9 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cupin_3 PF05899.12 CBY37151.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 CBY37151.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PAS_9 PF13426.7 CBY37152.1 - 4.2e-09 36.6 0.1 5.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CBY37152.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CBY37152.1 - 0.0028 17.7 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CBY37152.1 - 0.0053 17.0 0.1 0.0099 16.1 0.1 1.6 1 1 0 1 1 1 1 PAS fold Fucose_iso_N2 PF07882.12 CBY37152.1 - 0.096 12.3 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Peptidase_M1 PF01433.20 CBY37153.1 - 7.3e-49 166.3 0.9 7.3e-49 166.3 0.9 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY37153.1 - 1.1e-28 100.7 0.2 2e-28 99.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBY37153.1 - 1.2e-12 48.0 0.2 2.4e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain RepA_N PF06970.11 CBY37153.1 - 0.075 13.0 0.6 4.3 7.3 0.1 2.7 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus DUF1115 PF06544.12 CBY37155.1 - 2.1 8.4 11.2 0.3 11.2 6.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1115) FGF PF00167.18 CBY37156.1 - 4.3e-27 94.7 0.0 6e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Fascin PF06268.13 CBY37156.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Fascin domain Glyco_transf_7N PF13733.6 CBY37157.1 - 4.2e-33 113.8 0.6 7.6e-33 113.0 0.6 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY37157.1 - 4.2e-22 77.6 0.4 1.1e-21 76.2 0.2 1.9 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase PLAC8 PF04749.17 CBY37158.1 - 1.5e-06 29.1 10.8 2e-06 28.7 10.8 1.2 1 0 0 1 1 1 1 PLAC8 family Caveolin PF01146.17 CBY37159.1 - 1e-22 80.5 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Caveolin DNA_pol_A_exo1 PF01612.20 CBY37160.1 - 1.3e-42 145.5 0.3 2.8e-42 144.4 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CBY37160.1 - 1.7e-11 44.7 0.0 4.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 CBY37160.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DUF3638 PF12340.8 CBY37160.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Tox-ODYAM1 PF15642.6 CBY37161.1 - 0.095 11.7 9.2 0.11 11.5 9.2 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TMPIT PF07851.13 CBY37161.1 - 2.1 7.5 8.6 2.4 7.3 8.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4570 PF15134.6 CBY37161.1 - 2.6 8.1 14.6 4.2 7.4 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DUF4537 PF15057.6 CBY37162.1 - 6.7e-55 184.3 1.8 5.6e-28 97.4 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 CBY37162.1 - 8.7e-06 25.5 0.0 2.1 8.3 0.0 4.2 4 0 0 4 4 4 2 DNA repair protein Crb2 Tudor domain DUF4819 PF16090.5 CBY37162.1 - 0.003 17.6 0.4 19 5.4 0.0 3.9 2 2 1 4 4 4 2 Domain of unknown function (DUF4819) Tudor_2 PF18104.1 CBY37162.1 - 0.0083 15.8 0.5 1.2 8.9 0.0 4.3 5 0 0 5 5 5 1 Jumonji domain-containing protein 2A Tudor domain TUDOR_5 PF18359.1 CBY37162.1 - 0.053 13.2 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 DUF3668 PF12416.8 CBY37163.1 - 7.5e-19 68.4 1.2 2.9e-17 63.2 0.0 3.6 3 2 0 3 3 3 1 Cep120 protein DUF4497 PF14924.6 CBY37163.1 - 0.011 16.2 0.1 0.12 12.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) C2 PF00168.30 CBY37163.1 - 0.046 14.0 0.0 15 5.9 0.0 3.0 2 1 0 2 2 2 0 C2 domain NT-C2 PF10358.9 CBY37163.1 - 0.061 13.1 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins WD40 PF00400.32 CBY37164.1 - 1.4e-36 123.8 21.3 2.4e-06 28.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37164.1 - 3.5e-11 43.3 0.1 0.0019 18.4 0.1 4.6 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain OATP PF03137.20 CBY37165.1 - 1.9e-80 270.7 7.2 2.4e-80 270.4 7.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 CBY37165.1 - 3.1e-16 59.3 6.6 1e-13 51.0 1.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CBY37165.1 - 0.00096 17.8 0.5 0.00096 17.8 0.5 1.9 3 0 0 3 3 3 1 MFS/sugar transport protein Zona_pellucida PF00100.23 CBY37166.1 - 4.5e-37 128.3 1.3 8.8e-37 127.3 1.3 1.5 1 0 0 1 1 1 1 Zona pellucida-like domain wnt PF00110.19 CBY37167.1 - 1.4e-40 139.9 15.2 4.3e-29 102.1 10.3 2.0 1 1 1 2 2 2 2 wnt family Histone_H2A_C PF16211.5 CBY37168.1 - 3.4e-17 61.9 2.1 7.8e-17 60.7 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY37168.1 - 1.6e-16 60.9 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY37168.1 - 7.2e-06 26.2 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY37169.1 - 5.4e-18 65.6 0.1 6.6e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY37169.1 - 0.00013 22.1 0.1 0.0003 21.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY37169.1 - 0.0034 17.8 0.4 0.0099 16.4 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY37169.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 YscO-like protein Trypsin PF00089.26 CBY37170.1 - 8.3e-54 182.7 1.1 1.1e-53 182.3 1.1 1.1 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY37170.1 - 0.019 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Ig_3 PF13927.6 CBY37171.1 - 3.2e-17 62.9 0.6 4e-11 43.3 0.0 2.7 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY37171.1 - 8e-11 41.9 0.7 7.4e-06 25.9 0.1 2.7 2 1 0 2 2 2 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY37171.1 - 3.8e-07 30.4 0.3 0.00016 21.9 0.0 2.7 2 2 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CBY37171.1 - 5.7e-07 29.7 0.5 0.0025 18.0 0.0 3.2 2 2 1 3 3 3 2 Immunoglobulin V-set domain ig PF00047.25 CBY37171.1 - 0.00027 21.0 0.9 0.11 12.7 0.0 3.5 2 2 1 3 3 3 1 Immunoglobulin domain DUF724 PF05266.14 CBY37172.1 - 0.0006 19.7 8.2 0.00074 19.4 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Helo_like_N PF17111.5 CBY37172.1 - 0.0014 18.0 2.7 0.0028 17.1 2.7 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins APG6_N PF17675.1 CBY37172.1 - 0.017 15.6 10.8 0.024 15.2 10.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 CBY37172.1 - 0.02 13.8 7.5 0.026 13.4 7.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FapA PF03961.13 CBY37172.1 - 0.021 13.4 6.5 0.026 13.2 6.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 CBY37172.1 - 0.021 15.2 8.7 0.33 11.4 0.6 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 CBY37172.1 - 0.026 14.5 9.3 0.57 10.2 1.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 CBY37172.1 - 0.029 14.8 4.6 0.041 14.3 4.6 1.2 1 0 0 1 1 1 0 Fez1 DUF4988 PF16378.5 CBY37172.1 - 0.03 14.0 2.5 0.041 13.5 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function DivIVA PF05103.13 CBY37172.1 - 0.036 14.2 7.5 0.047 13.8 7.5 1.1 1 0 0 1 1 1 0 DivIVA protein HAP1_N PF04849.13 CBY37172.1 - 0.039 13.2 10.8 0.055 12.7 10.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Tropomyosin PF00261.20 CBY37172.1 - 0.047 13.1 8.3 1.5 8.1 3.0 2.0 1 1 1 2 2 2 0 Tropomyosin Leu_zip PF15294.6 CBY37172.1 - 0.052 13.1 9.9 0.063 12.8 9.9 1.0 1 0 0 1 1 1 0 Leucine zipper RasGAP_C PF03836.15 CBY37172.1 - 0.084 13.0 4.5 0.12 12.5 3.9 1.6 1 1 0 1 1 1 0 RasGAP C-terminus PspB PF06667.12 CBY37172.1 - 0.088 12.9 0.0 0.97 9.5 0.0 2.3 1 1 1 2 2 2 0 Phage shock protein B ERM PF00769.19 CBY37172.1 - 0.13 12.1 12.1 0.16 11.8 12.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APC_N_CC PF16689.5 CBY37172.1 - 0.21 11.7 6.3 0.85 9.7 0.9 2.5 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain CENP-F_leu_zip PF10473.9 CBY37172.1 - 0.22 11.6 14.7 0.87 9.6 4.4 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CBY37172.1 - 0.22 12.0 2.0 3.1 8.3 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 CBY37172.1 - 0.35 11.3 8.4 0.21 12.0 5.5 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) betaPIX_CC PF16523.5 CBY37172.1 - 0.4 10.5 6.1 2 8.3 0.7 2.2 1 1 1 2 2 2 0 betaPIX coiled coil DUF2730 PF10805.8 CBY37172.1 - 0.41 10.8 7.5 1.7 8.8 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BRE1 PF08647.11 CBY37172.1 - 0.42 10.7 9.8 4.6 7.4 2.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 CBY37172.1 - 0.62 10.1 6.0 1.8 8.6 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 CBY37172.1 - 0.66 10.7 9.5 18 6.1 9.5 2.3 1 1 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 CBY37172.1 - 1 9.7 7.9 2.8 8.3 7.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 CBY37172.1 - 1.1 9.4 7.7 3.5 7.8 1.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor TMPIT PF07851.13 CBY37172.1 - 1.2 8.3 5.8 1.5 8.0 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 CBY37172.1 - 1.2 9.4 4.3 0.75 10.1 1.1 2.1 1 1 1 2 2 2 0 Haemolysin XhlA CLZ PF16526.5 CBY37172.1 - 1.5 9.3 10.3 0.48 10.8 2.9 2.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0242 PF06785.11 CBY37172.1 - 2.3 8.3 9.9 9.1 6.3 10.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 CBY37172.1 - 2.9 8.1 9.1 2.2 8.5 2.2 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CC2-LZ PF16516.5 CBY37172.1 - 4.1 7.8 10.9 6.2 7.2 1.8 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF371 PF04027.13 CBY37173.1 - 0.039 13.9 0.0 0.045 13.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF371) Imm3 PF14425.6 CBY37173.1 - 0.056 13.5 0.1 0.063 13.3 0.1 1.0 1 0 0 1 1 1 0 Immunity protein Imm3 GH97_N PF14508.6 CBY37174.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Ribosomal_L7Ae PF01248.26 CBY37177.1 - 1.2e-15 57.0 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMC2NT PF08066.12 CBY37178.1 - 0.025 15.2 0.1 0.26 12.0 0.0 2.4 2 1 1 3 3 3 0 PMC2NT (NUC016) domain UPF0184 PF03670.13 CBY37178.1 - 0.11 12.9 0.3 0.23 11.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Sulfotransfer_2 PF03567.14 CBY37179.1 - 6e-37 127.9 1.2 8.5e-37 127.4 1.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Forkhead PF00250.18 CBY37180.1 - 9e-40 134.8 0.1 9e-40 134.8 0.1 2.0 2 0 0 2 2 2 1 Forkhead domain OmdA PF13376.6 CBY37180.1 - 0.016 15.2 1.0 0.041 13.9 1.0 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated GOLGA2L5 PF15070.6 CBY37180.1 - 0.035 12.8 1.5 0.05 12.3 1.5 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF4519 PF15012.6 CBY37180.1 - 0.37 11.0 7.7 0.57 10.4 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) PknG_rubred PF16919.5 CBY37182.1 - 0.023 14.9 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain MDM10 PF12519.8 CBY37182.1 - 0.2 10.5 1.1 1.7 7.4 0.0 1.8 1 1 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 VWA PF00092.28 CBY37183.1 - 4.2e-32 111.8 1.8 8.2e-32 110.8 1.8 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY37183.1 - 5.7e-13 49.5 1.4 2.9e-12 47.2 0.4 2.4 1 1 1 2 2 2 1 von Willebrand factor type A domain Pkinase PF00069.25 CBY37185.1 - 4.7e-53 180.2 0.0 1e-52 179.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37185.1 - 9.8e-34 116.8 0.0 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY37185.1 - 5e-26 90.3 28.0 4.4e-16 58.5 10.4 3.4 4 0 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CBY37185.1 - 7.4e-25 87.2 0.0 2e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain RhoGEF PF00621.20 CBY37185.1 - 1.1e-12 48.6 2.3 2.7e-12 47.3 2.3 1.7 1 0 0 1 1 1 1 RhoGEF domain Kinase-like PF14531.6 CBY37185.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY37185.1 - 0.0015 17.5 2.4 0.061 12.3 0.0 3.4 3 1 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY37185.1 - 0.0018 17.1 0.4 0.0036 16.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBY37185.1 - 0.095 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PI3K_C2 PF00792.24 CBY37185.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 PHD_2 PF13831.6 CBY37185.1 - 0.39 10.3 19.6 0.049 13.2 2.0 3.3 4 0 0 4 4 4 0 PHD-finger Zf_RING PF16744.5 CBY37185.1 - 1.1 9.4 16.3 1.5 8.9 2.5 3.5 3 0 0 3 3 3 0 KIAA1045 RING finger PHD_4 PF16866.5 CBY37185.1 - 5.1 7.3 13.2 5.8 7.1 0.4 3.6 3 1 0 3 3 3 0 PHD-finger C1_2 PF03107.16 CBY37185.1 - 5.5 7.4 20.2 3 8.2 3.4 3.4 3 0 0 3 3 3 0 C1 domain PLAT PF01477.23 CBY37186.1 - 7.1e-11 42.7 0.1 1e-10 42.2 0.1 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain ATS3 PF06232.11 CBY37186.1 - 0.00014 21.7 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) TMEM65 PF10507.9 CBY37187.1 - 4.7e-44 148.8 0.7 7.2e-44 148.2 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 Forkhead PF00250.18 CBY37188.1 - 1.4e-30 105.4 0.7 3.6e-30 104.1 0.0 2.0 2 0 0 2 2 2 1 Forkhead domain TFIIA PF03153.13 CBY37188.1 - 3.7 7.4 12.2 4.8 7.1 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.21 CBY37190.1 - 1.4e-174 582.1 0.2 1.6e-174 581.9 0.2 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CBY37190.1 - 0.00023 20.9 1.8 0.00058 19.6 1.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBY37190.1 - 0.025 14.8 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 CBY37190.1 - 0.065 12.1 0.7 0.095 11.6 0.4 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 CBY37190.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBY37190.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CBY37190.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATG13 PF10033.9 CBY37191.1 - 7.2e-11 42.2 1.9 2e-06 27.7 0.9 3.2 1 1 1 2 2 2 2 Autophagy-related protein 13 Acetyltransf_1 PF00583.25 CBY37192.1 - 7.2e-13 48.8 0.0 9.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY37192.1 - 6.5e-07 29.7 0.1 1.1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY37192.1 - 2.3e-05 24.3 0.0 4.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CBY37192.1 - 4.1e-05 23.5 0.1 7.4e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY37192.1 - 0.00013 22.1 0.0 0.00048 20.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBY37192.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Gly_acyl_tr_C PF08444.10 CBY37192.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region MUG113 PF13455.6 CBY37192.1 - 0.15 12.7 0.9 0.31 11.7 0.2 1.9 2 1 0 2 2 2 0 Meiotically up-regulated gene 113 DNA_pol_alpha_N PF12254.8 CBY37193.1 - 0.02 14.9 0.2 0.027 14.6 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal CIDR1_gamma PF18562.1 CBY37194.1 - 0.069 13.2 1.2 0.13 12.4 1.2 1.4 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma Thiolase_N PF00108.23 CBY37196.1 - 1.5e-71 240.8 0.8 1.9e-70 237.2 0.2 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY37196.1 - 7.1e-37 125.8 0.3 1.8e-36 124.5 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY37196.1 - 9.1e-06 25.4 0.3 0.00017 21.2 0.1 2.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Latrotoxin_C PF15658.6 CBY37196.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain ACP_syn_III PF08545.10 CBY37196.1 - 1.3 8.9 8.7 1 9.3 0.2 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LRR_8 PF13855.6 CBY37198.1 - 9.6e-11 41.3 8.9 2.1e-08 33.8 1.9 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY37198.1 - 1e-05 25.8 5.0 0.0029 18.0 0.2 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY37198.1 - 0.00094 19.4 5.7 1.2 10.0 0.1 3.5 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY37198.1 - 0.064 13.3 5.1 6.2 7.1 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat MFA1_2 PF17317.2 CBY37199.1 - 0.075 12.8 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 CUB PF00431.20 CBY37201.1 - 0.00019 21.8 0.1 0.00026 21.3 0.1 1.2 1 0 0 1 1 1 1 CUB domain CUT PF02376.15 CBY37204.1 - 0.024 14.8 0.1 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 CUT domain HEM4 PF02602.15 CBY37204.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD p450 PF00067.22 CBY37206.1 - 1.9e-24 86.3 0.2 2.4e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.17 CBY37207.1 - 2.7e-06 26.9 0.2 1.6e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PIP49_C PF12260.8 CBY37207.1 - 4.8e-05 23.1 0.1 7.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase PF00069.25 CBY37207.1 - 0.0053 16.2 0.1 0.1 12.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain RICTOR_M PF14666.6 CBY37207.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain CbiC PF02570.15 CBY37207.1 - 0.2 11.3 0.0 0.97 9.1 0.0 1.8 2 0 0 2 2 2 0 Precorrin-8X methylmutase Sulfotransfer_3 PF13469.6 CBY37208.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY37209.1 - 3.8e-40 138.6 0.5 1.5e-37 130.1 0.5 2.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY37209.1 - 1.8e-11 44.0 0.2 4.1e-11 42.9 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CBY37209.1 - 0.014 15.2 1.2 0.07 12.9 1.2 2.2 1 1 0 1 1 1 0 Sulfotransferase domain Glyco_hydro_20 PF00728.22 CBY37210.1 - 1.4e-50 172.7 0.0 2.1e-41 142.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain PP2C PF00481.21 CBY37212.1 - 7.8e-08 32.3 0.1 9e-08 32.1 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF677 PF05055.12 CBY37212.1 - 0.032 13.1 0.2 0.036 13.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Staph_haemo PF05480.11 CBY37212.1 - 0.057 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein TIR PF01582.20 CBY37212.1 - 0.098 12.4 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 TIR domain COesterase PF00135.28 CBY37213.1 - 8e-91 305.4 0.0 9.5e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY37213.1 - 2.4e-08 34.1 0.6 2.6e-07 30.7 0.6 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY37213.1 - 0.038 13.5 0.1 0.038 13.5 0.1 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Kinesin PF00225.23 CBY37214.1 - 4.3e-109 364.5 0.2 4.3e-109 364.5 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY37214.1 - 1.6e-28 99.6 1.3 4.8e-28 98.0 0.2 2.5 2 0 0 2 2 2 1 Microtubule binding CEP209_CC5 PF16574.5 CBY37214.1 - 3.3 7.9 14.9 2 8.6 0.4 4.0 4 0 0 4 4 4 0 Coiled-coil region of centrosome protein CE290 ASD2 PF08687.11 CBY37214.1 - 4.7 6.7 21.4 9.5 5.7 14.4 2.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Ank_2 PF12796.7 CBY37215.1 - 0.00031 21.3 0.0 0.00051 20.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C4 PF00105.18 CBY37216.1 - 3.7e-27 94.6 15.8 7.8e-27 93.5 15.8 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY37216.1 - 0.1 12.2 1.1 0.32 10.6 0.6 2.0 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor DUF4562 PF15123.6 CBY37217.1 - 5.5e-11 42.4 0.0 6.4e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) RRM_1 PF00076.22 CBY37218.1 - 0.05 13.4 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.20 CBY37221.1 - 3e-32 112.3 9.2 3e-32 112.3 9.2 2.0 2 0 0 2 2 2 1 RhoGEF domain SH2 PF00017.24 CBY37221.1 - 1e-09 38.4 0.2 3.6e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 SH2 domain DUF1007 PF06226.13 CBY37221.1 - 0.1 12.6 0.4 0.29 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) PHD PF00628.29 CBY37222.1 - 0.01 15.7 11.4 0.032 14.1 11.4 1.9 1 0 0 1 1 1 0 PHD-finger DNA_RNApol_7kD PF03604.13 CBY37222.1 - 0.04 13.6 1.2 0.04 13.6 1.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FXMRP1_C_core PF12235.8 CBY37222.1 - 8.4 7.0 22.0 0.23 12.1 7.4 2.6 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Sas10 PF09368.10 CBY37223.1 - 2.2e-16 60.1 9.6 2.4e-16 60.0 9.6 1.0 1 0 0 1 1 1 1 Sas10 C-terminal domain Alfin PF12165.8 CBY37223.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Alfin Cys_rich_VLP PF14194.6 CBY37224.1 - 0.24 11.6 2.7 0.56 10.4 2.7 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Sh_2 PF17512.2 CBY37224.1 - 0.76 9.5 13.4 0.016 15.0 3.7 2.0 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein Pkinase PF00069.25 CBY37225.1 - 5.7e-11 42.3 1.3 6.7e-10 38.8 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37225.1 - 2e-07 30.6 0.4 3.9e-07 29.6 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase GatB_Yqey PF02637.18 CBY37225.1 - 0.19 11.6 0.7 7.8 6.4 0.1 2.4 2 0 0 2 2 2 0 GatB domain UBA_4 PF14555.6 CBY37226.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 CBY37226.1 - 0.00068 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 CBY37226.1 - 0.0055 16.6 0.6 0.033 14.1 0.6 2.4 1 1 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 CBY37226.1 - 0.017 15.2 0.6 0.02 14.9 0.6 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair YopE_N PF09020.10 CBY37226.1 - 0.065 13.5 0.5 0.096 12.9 0.4 1.4 1 1 0 1 1 1 0 YopE, N terminal DUF2203 PF09969.9 CBY37226.1 - 0.093 13.5 0.1 0.11 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2250 PF10007.9 CBY37226.1 - 0.099 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DHHC PF01529.20 CBY37229.1 - 5.2e-30 104.3 5.8 5.2e-30 104.3 5.8 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PRiA4_ORF3 PF07929.11 CBY37229.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein ERAP1_C PF11838.8 CBY37230.1 - 7e-24 84.9 0.3 8.8e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Cadherin_3 PF16184.5 CBY37231.1 - 2.5e-193 629.6 36.5 1.2e-25 89.7 0.4 15.1 15 0 0 15 15 15 11 Cadherin-like Calx-beta PF03160.14 CBY37231.1 - 2.4e-66 220.2 18.7 4.7e-14 52.4 0.0 6.5 5 0 0 5 5 5 5 Calx-beta domain Big_9 PF17963.1 CBY37231.1 - 7.9e-11 42.6 12.6 0.00041 21.0 0.1 9.5 9 0 0 9 9 9 2 Bacterial Ig domain Cadherin_4 PF17803.1 CBY37231.1 - 2.1e-08 34.6 3.8 1.3 9.6 0.0 8.3 9 0 0 9 9 9 2 Bacterial cadherin-like domain Filamin PF00630.19 CBY37231.1 - 0.093 13.6 0.9 1.7e+02 3.1 0.0 4.9 3 1 1 4 4 4 0 Filamin/ABP280 repeat CALCOCO1 PF07888.11 CBY37233.1 - 0.00026 20.0 19.0 0.00038 19.4 19.0 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C3HC4_3 PF13920.6 CBY37233.1 - 0.00029 20.6 15.1 0.00029 20.6 15.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY37233.1 - 0.001 19.1 13.5 0.001 19.1 13.5 2.5 1 1 2 3 3 3 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CBY37233.1 - 0.014 15.7 17.1 0.014 15.7 17.1 3.0 3 1 0 3 3 3 0 Ring finger domain Jnk-SapK_ap_N PF09744.9 CBY37233.1 - 0.22 11.8 28.2 0.14 12.4 15.7 2.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Prok-RING_4 PF14447.6 CBY37233.1 - 0.28 11.1 20.8 0.035 14.0 14.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Spc7 PF08317.11 CBY37233.1 - 0.55 9.1 29.2 0.58 9.0 0.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-RING_6 PF14835.6 CBY37233.1 - 0.9 9.5 10.3 0.14 12.1 6.2 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MCM3AP_GANP PF16769.5 CBY37233.1 - 1.4 7.1 17.5 1.7 6.8 17.5 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP zf-ACC PF17848.1 CBY37233.1 - 2.1 8.5 13.6 2.4 8.3 0.4 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain SlyX PF04102.12 CBY37233.1 - 2.5 8.8 12.3 0.25 12.0 1.6 3.5 1 1 2 3 3 3 0 SlyX PhoU PF01895.19 CBY37233.1 - 8.8 6.9 8.3 3.1 8.3 1.2 2.9 3 0 0 3 3 3 0 PhoU domain zf-C3HC4_3 PF13920.6 CBY37234.1 - 0.00021 21.1 15.2 0.00021 21.1 15.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY37234.1 - 0.0023 18.0 14.4 0.0023 18.0 14.4 2.5 2 1 1 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 CBY37234.1 - 0.02 14.7 18.3 0.02 14.7 18.3 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY37234.1 - 0.14 12.1 6.1 0.36 10.7 6.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ERM PF00769.19 CBY37234.1 - 1.1 9.0 45.1 4.8 6.9 16.4 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Prok-RING_4 PF14447.6 CBY37234.1 - 1.4 8.9 19.9 0.15 12.0 13.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SpoVT_C PF15714.5 CBY37234.1 - 2 8.5 10.8 2.7 8.1 7.3 2.8 1 1 1 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor UPF0016 PF01169.19 CBY37235.1 - 6.6e-37 125.7 19.8 1.5e-18 66.9 8.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF373 PF04123.13 CBY37235.1 - 0.28 10.6 3.1 1 8.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) EGF_3 PF12947.7 CBY37236.1 - 3.9e-07 30.2 27.9 8.2e-06 25.9 5.9 3.6 3 0 0 3 3 3 2 EGF domain Lectin_C PF00059.21 CBY37236.1 - 1.3e-05 25.9 0.2 3.7e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 Lectin C-type domain Plasmod_Pvs28 PF06247.11 CBY37236.1 - 0.013 15.8 4.7 0.013 15.8 4.7 3.8 4 0 0 4 4 4 0 Pvs28 EGF domain EGF PF00008.27 CBY37236.1 - 5.6 7.4 26.7 0.086 13.2 2.6 4.5 3 1 0 3 3 3 0 EGF-like domain Collagen PF01391.18 CBY37240.1 - 4.8e-12 45.4 53.7 8.2e-08 31.9 32.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Cu-oxidase_3 PF07732.15 CBY37241.1 - 2.8e-35 120.9 0.3 3e-35 120.8 0.3 1.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY37241.1 - 0.00051 19.8 3.2 0.024 14.4 3.2 2.0 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY37242.1 - 1.5e-22 79.8 0.3 2.3e-22 79.2 0.3 1.4 1 0 0 1 1 1 1 Multicopper oxidase PyrI_C PF02748.15 CBY37242.1 - 0.091 12.7 0.1 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain YGGT PF02325.17 CBY37243.1 - 0.09 13.2 0.2 0.13 12.7 0.2 1.2 1 0 0 1 1 1 0 YGGT family Ank_4 PF13637.6 CBY37245.1 - 9.3e-13 48.4 0.7 5.5e-09 36.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY37245.1 - 8.3e-11 41.8 0.1 1.7e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CBY37245.1 - 8.5e-11 42.3 0.3 1.4e-06 28.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY37245.1 - 4.1e-10 39.0 0.3 0.004 17.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY37245.1 - 1.3e-09 38.1 0.3 1.1e-05 25.5 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Kringle PF00051.18 CBY37246.1 - 6.7e-19 68.0 6.0 1.6e-18 66.8 6.0 1.7 1 0 0 1 1 1 1 Kringle domain FXa_inhibition PF14670.6 CBY37246.1 - 1.5e-05 25.1 3.1 4.2e-05 23.7 3.1 1.7 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site Ldl_recept_b PF00058.17 CBY37246.1 - 2.2e-05 24.8 12.2 0.49 10.9 0.1 5.4 5 0 0 5 5 5 3 Low-density lipoprotein receptor repeat class B LGFP PF08310.11 CBY37246.1 - 0.32 11.6 7.4 1.2 9.7 0.2 4.4 3 2 2 5 5 5 0 LGFP repeat STG PF15809.5 CBY37249.1 - 0.049 13.7 0.6 0.08 13.0 0.4 1.3 1 1 0 1 1 1 0 Simian taste bud-specific gene product family UQ_con PF00179.26 CBY37251.1 - 1.2e-45 154.6 0.1 1.3e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY37251.1 - 0.0029 17.3 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY37251.1 - 0.0034 17.7 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 CBY37251.1 - 0.038 13.9 0.2 0.071 13.0 0.2 1.5 1 1 0 1 1 1 0 UEV domain Neur_chan_LBD PF02931.23 CBY37252.1 - 1.3e-39 135.8 0.0 1.8e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY37252.1 - 2.9e-17 63.5 12.5 5.7e-11 42.9 2.0 3.0 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region Trypsin PF00089.26 CBY37253.1 - 1.3e-47 162.4 0.9 4.2e-47 160.8 0.9 1.8 1 1 0 1 1 1 1 Trypsin Actin PF00022.19 CBY37254.1 - 6.7e-115 384.0 0.0 4.9e-114 381.1 0.0 1.8 1 1 0 1 1 1 1 Actin Sulfotransfer_3 PF13469.6 CBY37257.1 - 0.0025 18.2 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY37257.1 - 0.032 13.7 0.2 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase domain Na_H_Exchanger PF00999.21 CBY37259.1 - 2.4e-73 247.1 31.7 2.8e-73 246.9 31.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ras PF00071.22 CBY37260.1 - 3.5e-36 124.2 0.0 4e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37260.1 - 8.1e-30 103.5 0.0 9.9e-30 103.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37260.1 - 2.7e-07 30.2 0.0 3e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY37260.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY37260.1 - 0.0014 19.1 0.1 0.0017 18.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBY37260.1 - 0.0021 18.0 0.3 0.0072 16.2 0.3 1.8 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBY37260.1 - 0.0054 16.3 0.1 0.066 12.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ParA PF10609.9 CBY37260.1 - 0.0086 15.5 0.1 0.009 15.5 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase PduV-EutP PF10662.9 CBY37260.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CBY37260.1 - 0.022 14.7 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CBY37260.1 - 0.024 14.9 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY37260.1 - 0.026 14.3 0.1 0.041 13.6 0.1 1.3 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CBY37260.1 - 0.026 13.9 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 CBY37260.1 - 0.029 13.7 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CBY37260.1 - 0.036 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CBY37260.1 - 0.073 12.8 0.2 5.9 6.6 0.2 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein VirE PF05272.11 CBY37260.1 - 0.078 12.7 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_5 PF07728.14 CBY37260.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBY37260.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) MeaB PF03308.16 CBY37260.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CBY37260.1 - 0.16 11.1 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ammonium_transp PF00909.21 CBY37261.1 - 3.2e-107 358.7 28.2 3.8e-107 358.5 28.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4818 PF16089.5 CBY37261.1 - 2.2 8.8 9.6 13 6.2 1.7 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4818) Sad1_UNC PF07738.13 CBY37262.1 - 1.1e-30 106.3 0.0 3e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal APG17 PF04108.12 CBY37262.1 - 0.1 11.7 2.4 0.14 11.2 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 RRM_1 PF00076.22 CBY37263.1 - 1.2e-17 63.5 2.7 1.2e-11 44.2 0.2 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 CBY37265.1 - 1.5e-28 99.6 0.0 2.9e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 SPOC domain DPPIV_N PF00930.21 CBY37267.1 - 8.6e-36 123.4 8.7 7.2e-35 120.4 8.7 2.1 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CBY37267.1 - 6.5e-33 114.0 2.8 1.2e-32 113.1 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Metallophos PF00149.28 CBY37268.1 - 2.6e-15 57.5 2.1 3.6e-15 57.0 2.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CreA PF05981.12 CBY37269.1 - 0.077 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 CreA protein WD40 PF00400.32 CBY37272.1 - 4.8e-05 24.1 3.8 0.53 11.2 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 CBY37273.1 - 0.007 17.2 0.1 0.62 11.0 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat PCI PF01399.27 CBY37274.1 - 3.6e-19 69.2 1.5 3.6e-19 69.2 1.5 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CBY37274.1 - 0.041 14.0 4.1 0.077 13.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY37274.1 - 0.3 11.0 1.3 0.78 9.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 CBY37275.1 - 5.8e-44 150.6 0.0 9.5e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY37275.1 - 0.00087 19.0 0.4 0.0033 17.1 0.4 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C eIF3_subunit PF08597.10 CBY37275.1 - 0.29 11.0 10.1 0.51 10.2 10.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRM_1 PF00076.22 CBY37276.1 - 2e-25 88.4 0.0 5.5e-14 51.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CBY37276.1 - 1.4e-08 35.7 0.4 1.4e-08 35.7 0.4 3.2 3 2 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Ndc1_Nup PF09531.10 CBY37276.1 - 7.7 5.1 14.2 9.7 4.7 14.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Astacin PF01400.24 CBY37277.1 - 2.3e-23 82.8 0.0 4.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY37277.1 - 5.7e-18 64.8 61.6 4.4e-06 26.8 11.0 6.6 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 CBY37277.1 - 3.2e-11 42.9 24.1 0.00059 19.7 0.7 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY37277.1 - 4.3e-09 36.4 23.7 2.6e-07 30.7 14.0 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.27 CBY37277.1 - 0.017 15.4 62.1 0.019 15.2 3.5 6.2 5 1 0 5 5 5 0 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY37277.1 - 0.4 11.0 33.6 0.089 13.1 1.7 4.8 4 0 0 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY37277.1 - 1.8 8.9 53.7 0.14 12.5 3.7 5.6 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site Astacin PF01400.24 CBY37278.1 - 2.1e-23 82.9 0.0 3.9e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY37278.1 - 4.7e-18 65.1 61.6 4.1e-06 26.9 11.0 6.5 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.7 CBY37278.1 - 2.6e-11 43.3 24.1 0.00056 19.8 0.7 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY37278.1 - 3.6e-09 36.7 23.7 2.4e-07 30.8 14.0 5.6 5 0 0 5 5 5 2 EGF domain EGF PF00008.27 CBY37278.1 - 0.017 15.4 62.4 0.019 15.2 3.6 6.1 5 1 0 5 5 5 0 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY37278.1 - 0.34 11.3 33.6 0.084 13.2 1.7 4.7 4 0 0 4 4 4 0 Pvs28 EGF domain FXa_inhibition PF14670.6 CBY37278.1 - 1.2 9.5 53.6 0.13 12.6 3.7 5.5 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY37278.1 - 8.7 6.5 28.6 2 8.6 3.1 4.8 4 0 0 4 4 4 0 MSP1 EGF domain 1 Tctex-1 PF03645.13 CBY37282.1 - 4.8e-11 42.8 0.0 6.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family zf-C2H2 PF00096.26 CBY37283.1 - 7.9e-43 142.6 87.2 8.5e-05 22.8 0.3 13.1 12 2 1 13 13 13 12 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37283.1 - 1.1e-26 91.1 90.6 0.0049 17.6 0.1 12.7 12 1 0 12 12 12 11 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY37283.1 - 2.5e-18 65.6 109.8 0.0024 18.2 6.5 13.5 13 1 0 13 13 13 10 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY37283.1 - 1.6e-16 59.9 81.9 8.8e-06 25.6 1.6 12.1 12 0 0 12 12 12 6 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY37283.1 - 1.1e-07 31.5 43.4 0.049 13.4 0.0 10.7 12 0 0 12 12 12 3 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 CBY37283.1 - 1.3e-07 32.3 58.1 8.4e-05 23.2 6.1 7.0 3 2 1 6 6 6 3 Zinc finger C2H2-type, 3 repeats CpXC PF14353.6 CBY37283.1 - 1.1e-05 25.5 63.0 0.72 9.9 2.0 10.5 1 1 10 11 11 11 4 CpXC protein zf-C2H2_8 PF15909.5 CBY37283.1 - 3.5e-05 24.0 65.0 2.4 8.5 0.7 8.8 4 4 3 8 8 8 5 C2H2-type zinc ribbon zf-met PF12874.7 CBY37283.1 - 4.4e-05 23.7 69.7 0.0036 17.6 1.2 10.8 12 0 0 12 12 12 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY37283.1 - 8.7e-05 22.7 86.7 0.0026 18.0 2.2 12.2 12 0 0 12 12 12 4 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CBY37283.1 - 0.00053 19.5 53.7 0.82 9.3 0.5 11.7 12 0 0 12 12 12 4 Ubiquitin-Binding Zinc Finger zinc_ribbon_5 PF13719.6 CBY37283.1 - 0.013 15.3 0.5 0.013 15.3 0.5 10.6 11 1 0 11 11 10 0 zinc-ribbon domain zf-H2C2_5 PF13909.6 CBY37283.1 - 1.7 8.5 42.7 5.4 6.9 0.1 7.7 7 0 0 7 7 7 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 CBY37283.1 - 3.7 7.5 61.5 0.14 12.2 0.3 10.5 9 3 0 9 9 9 0 zinc-ribbon domain HypA PF01155.19 CBY37283.1 - 5.8 7.0 61.2 6 6.9 2.1 8.4 4 4 6 10 10 10 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ASC PF00858.24 CBY37284.1 - 8.6e-80 268.9 7.2 4.5e-78 263.2 7.2 2.0 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel ASC PF00858.24 CBY37285.1 - 1e-62 212.6 9.0 1.2e-62 212.3 9.0 1.0 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel M11L PF11099.8 CBY37285.1 - 0.37 11.0 3.9 0.89 9.8 3.9 1.6 1 0 0 1 1 1 0 Apoptosis regulator M11L like 5_nucleotid PF05761.14 CBY37286.1 - 3.7e-84 283.2 5.4 4.5e-84 283.0 5.4 1.0 1 0 0 1 1 1 1 5' nucleotidase family LisH_2 PF16045.5 CBY37286.1 - 0.018 14.1 0.7 7.4 5.7 0.0 3.5 3 0 0 3 3 3 0 LisH 5_nucleotid PF05761.14 CBY37287.1 - 4.4e-128 428.0 2.4 5e-128 427.9 2.4 1.0 1 0 0 1 1 1 1 5' nucleotidase family LisH_2 PF16045.5 CBY37287.1 - 0.13 11.3 2.3 9.5 5.3 0.0 3.3 3 0 0 3 3 3 0 LisH ABC_tran PF00005.27 CBY37288.1 - 8.5e-11 42.5 0.0 1.7e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY37288.1 - 5.4e-07 29.7 0.0 7.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY37288.1 - 0.00052 19.5 0.0 0.00064 19.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CBY37288.1 - 0.21 11.8 0.6 1.4 9.2 0.2 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad60-SLD PF11976.8 CBY37289.1 - 1.5e-09 37.5 0.0 3.7e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY37289.1 - 1.6e-05 24.5 0.6 5.2e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family ATG16 PF08614.11 CBY37289.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-H PF05837.12 CBY37289.1 - 0.025 15.0 7.3 0.053 13.9 7.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1663 PF07909.11 CBY37289.1 - 0.17 10.6 2.2 0.25 10.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) Peptidase_C57 PF03290.13 CBY37289.1 - 1.3 7.7 4.6 0.29 9.8 1.5 1.4 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase AAA PF00004.29 CBY37290.1 - 3.7e-40 137.4 0.0 8.5e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY37290.1 - 1.4e-12 47.4 0.2 1.7e-11 43.9 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CBY37290.1 - 5e-09 35.8 0.1 5.8e-08 32.4 0.1 2.6 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBY37290.1 - 3.8e-05 23.5 0.0 8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY37290.1 - 0.00021 21.5 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBY37290.1 - 0.00035 20.7 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CBY37290.1 - 0.00075 18.8 0.0 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 CBY37290.1 - 0.0024 18.3 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBY37290.1 - 0.0024 17.9 0.1 0.02 14.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY37290.1 - 0.0035 17.6 0.1 0.1 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 CBY37290.1 - 0.0037 17.3 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CBY37290.1 - 0.0065 15.9 0.4 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Macoilin PF09726.9 CBY37290.1 - 0.0088 14.7 0.5 0.012 14.2 0.5 1.2 1 0 0 1 1 1 1 Macoilin family IstB_IS21 PF01695.17 CBY37290.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBY37290.1 - 0.017 15.1 0.0 0.059 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY37290.1 - 0.026 14.1 0.2 0.099 12.2 0.1 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region Ndc1_Nup PF09531.10 CBY37290.1 - 0.028 13.1 3.9 0.038 12.7 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNA_helicase PF00910.22 CBY37290.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 CBY37290.1 - 0.035 14.7 0.6 0.19 12.3 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBY37290.1 - 0.044 13.6 6.2 0.13 12.0 0.5 2.5 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY37290.1 - 0.052 12.9 0.0 1.8 7.8 0.0 2.5 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 CBY37290.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBY37290.1 - 0.11 12.2 0.0 0.55 9.9 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Cytochrom_B562 PF07361.11 CBY37290.1 - 0.12 13.1 0.7 0.57 10.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b562 NACHT PF05729.12 CBY37290.1 - 0.14 12.1 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_3 PF07726.11 CBY37290.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CBY37290.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Hydin_ADK PF17213.3 CBY37290.1 - 0.24 11.7 3.3 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Lactamase_B_2 PF12706.7 CBY37291.1 - 4.2e-18 65.6 0.0 1.4e-07 31.3 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBY37291.1 - 2.7e-10 40.6 0.0 3.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 CBY37291.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease DOMON PF03351.17 CBY37292.1 - 1.4e-12 47.9 0.2 2.2e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CBY37292.1 - 8.4e-08 32.4 1.1 8.4e-08 32.4 1.1 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 CBY37292.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 CBY37292.1 - 0.0057 16.5 0.1 0.0057 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ODV-E18 PF10717.9 CBY37292.1 - 0.12 12.2 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4079 PF13301.6 CBY37292.1 - 0.15 12.3 5.9 0.026 14.7 1.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CBY37292.1 - 1.2 8.7 11.8 12 5.5 11.8 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 UBA_4 PF14555.6 CBY37293.1 - 1.5e-06 27.9 0.1 3.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CBY37293.1 - 0.02 14.5 0.2 0.042 13.5 0.2 1.4 1 0 0 1 1 1 0 TAP C-terminal domain DHC_N1 PF08385.12 CBY37294.1 - 5.9e-74 249.7 8.0 1.4e-43 149.4 0.7 2.4 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 PhaP_Bmeg PF09602.10 CBY37294.1 - 0.013 15.4 3.0 0.037 14.0 0.6 2.3 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) EGF_CA PF07645.15 CBY37295.1 - 2.2e-09 37.3 8.2 3.5e-09 36.7 8.2 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY37295.1 - 0.00072 19.7 7.0 0.00072 19.7 7.0 1.4 2 0 0 2 2 2 1 EGF domain Plasmod_Pvs28 PF06247.11 CBY37295.1 - 0.0013 19.0 0.1 0.0015 18.8 0.1 1.3 1 0 0 1 1 1 1 Pvs28 EGF domain Aa_trans PF01490.18 CBY37297.1 - 3e-28 98.7 17.1 3.6e-28 98.4 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SpoU_methylas_C PF12105.8 CBY37297.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Ndc1_Nup PF09531.10 CBY37297.1 - 2.8 6.5 6.8 3.7 6.1 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup I-set PF07679.16 CBY37298.1 - 2.2e-27 95.0 0.2 7e-06 26.0 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY37298.1 - 1.4e-16 60.9 0.5 0.0023 18.5 0.0 4.3 4 0 0 4 4 4 4 Immunoglobulin domain ig PF00047.25 CBY37298.1 - 1.3e-11 44.5 2.4 0.0017 18.5 0.0 4.2 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY37298.1 - 1e-09 38.6 0.7 0.63 10.4 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY37298.1 - 1.4e-06 28.5 1.3 0.072 13.3 0.0 3.9 3 1 0 3 3 3 2 Immunoglobulin V-set domain fn3 PF00041.21 CBY37298.1 - 7.1e-05 23.1 0.1 0.00085 19.6 0.0 2.5 3 0 0 3 3 2 1 Fibronectin type III domain C2-set_2 PF08205.12 CBY37298.1 - 0.061 13.4 0.1 17 5.6 0.0 2.7 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY37298.1 - 0.11 13.1 0.4 1.6 9.3 0.0 2.6 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 CBY37298.1 - 0.14 12.7 0.0 0.55 10.8 0.0 2.0 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain PRIMA1 PF16101.5 CBY37298.1 - 0.55 10.3 5.2 1.1 9.3 5.2 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4407 PF14362.6 CBY37298.1 - 1.3 8.3 5.5 0.47 9.8 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 CBY37299.1 - 3.8e-05 23.5 0.1 6.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY37299.1 - 0.00049 19.9 0.5 0.0013 18.5 0.3 1.7 1 1 0 1 1 1 1 F-box domain Acetyltransf_1 PF00583.25 CBY37300.1 - 2.3e-14 53.6 0.0 2.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY37300.1 - 2.5e-09 37.4 0.1 3.6e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY37300.1 - 6.6e-06 26.1 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY37300.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CBY37300.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CBY37300.1 - 0.073 13.7 0.1 0.12 13.1 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBY37300.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Lon_C PF05362.13 CBY37301.1 - 1.5e-38 132.5 0.1 4.3e-38 130.9 0.1 1.9 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CBY37301.1 - 1.1e-22 80.8 0.0 1e-21 77.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CBY37301.1 - 6e-08 32.8 0.4 1.3e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain RuvB_N PF05496.12 CBY37301.1 - 1.1e-07 31.8 0.0 3.1e-06 27.0 0.0 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CBY37301.1 - 9.6e-07 29.1 0.1 1.1e-05 25.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 CBY37301.1 - 5.3e-06 25.6 0.1 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_5 PF07728.14 CBY37301.1 - 5.5e-06 26.4 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY37301.1 - 7.8e-06 26.4 0.1 6.5e-05 23.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBY37301.1 - 4.9e-05 23.6 1.9 0.0052 17.1 0.1 3.9 2 2 1 3 3 3 1 AAA domain AAA_11 PF13086.6 CBY37301.1 - 0.0015 18.4 2.3 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBY37301.1 - 0.0028 16.9 0.0 0.0028 16.9 0.0 3.2 3 1 0 4 4 4 1 TIP49 P-loop domain AAA_33 PF13671.6 CBY37301.1 - 0.0039 17.3 0.7 0.017 15.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY37301.1 - 0.004 17.5 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase NB-ARC PF00931.22 CBY37301.1 - 0.0051 16.0 0.5 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 CBY37301.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 CBY37301.1 - 0.0075 16.3 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY37301.1 - 0.0086 16.6 0.5 0.032 14.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 CBY37301.1 - 0.011 16.3 3.0 0.18 12.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Torsin PF06309.11 CBY37301.1 - 0.014 15.5 0.0 0.052 13.7 0.0 2.0 1 0 0 1 1 1 0 Torsin IstB_IS21 PF01695.17 CBY37301.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 CBY37301.1 - 0.017 14.9 2.2 0.14 11.9 0.0 2.8 2 1 0 2 2 2 0 Cytidylate kinase Nucleoporin_C PF03177.14 CBY37301.1 - 0.017 13.9 2.3 0.03 13.1 2.3 1.3 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal TsaE PF02367.17 CBY37301.1 - 0.022 14.8 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBY37301.1 - 0.023 14.6 0.1 0.25 11.2 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CBY37301.1 - 0.024 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CBY37301.1 - 0.026 14.5 0.2 2 8.3 0.0 3.0 1 1 1 2 2 2 0 NTPase Mg_chelatase PF01078.21 CBY37301.1 - 0.029 13.8 0.1 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CBY37301.1 - 0.041 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_6 PF12774.7 CBY37301.1 - 0.047 12.6 0.7 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 CBY37301.1 - 0.053 13.4 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBY37301.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBY37301.1 - 0.11 12.9 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY37301.1 - 0.15 12.0 1.4 0.41 10.6 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 CBY37301.1 - 4.1 7.8 7.5 0.91 9.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBY37301.1 - 4.9 7.7 7.7 0.62 10.6 0.1 2.9 3 1 0 4 4 3 0 ABC transporter FH2 PF02181.23 CBY37302.1 - 3.2e-05 23.2 0.0 3.6e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain SCIMP PF15050.6 CBY37303.1 - 0.2 12.1 6.2 0.094 13.2 3.4 1.8 1 1 0 2 2 2 0 SCIMP protein RT_RNaseH_2 PF17919.1 CBY37304.1 - 3.7e-24 84.7 0.0 6.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY37304.1 - 9.1e-21 74.1 0.0 2.2e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase SUI1 PF01253.22 CBY37306.1 - 5.7e-21 74.8 0.3 9.6e-21 74.1 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 eIF-5_eIF-2B PF01873.17 CBY37306.1 - 0.066 13.1 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Cadherin_3 PF16184.5 CBY37307.1 - 2.2e-48 162.9 7.2 1.1e-25 89.7 0.4 3.4 4 0 0 4 4 4 3 Cadherin-like Big_9 PF17963.1 CBY37307.1 - 2.4e-06 28.2 0.6 0.00039 21.1 0.1 2.2 2 0 0 2 2 2 2 Bacterial Ig domain OLF PF02191.16 CBY37308.1 - 3.6e-56 190.5 2.0 4.7e-56 190.1 2.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Sushi PF00084.20 CBY37309.1 - 0.59 10.8 6.7 1.1 9.9 6.7 1.5 1 1 0 1 1 1 0 Sushi repeat (SCR repeat) GyrB_insert PF18053.1 CBY37310.1 - 0.0039 17.1 0.1 0.031 14.2 0.0 2.3 3 0 0 3 3 3 1 DNA gyrase B subunit insert domain SwrA PF17423.2 CBY37310.1 - 0.045 13.7 0.7 0.67 9.9 0.1 2.9 2 1 1 3 3 3 0 Swarming motility protein Metallophos PF00149.28 CBY37311.1 - 2.4e-31 109.8 0.0 3.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase La PF05383.17 CBY37312.1 - 1.6e-14 53.7 0.1 2.9e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 La domain SUZ-C PF12901.7 CBY37312.1 - 0.0003 20.7 0.0 0.0009 19.2 0.0 1.8 1 0 0 1 1 1 1 SUZ-C motif RRM_1 PF00076.22 CBY37312.1 - 0.00053 19.8 0.1 0.004 16.9 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shisa PF13908.6 CBY37313.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator MLANA PF14991.6 CBY37313.1 - 0.0063 16.8 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein melan-A PsaL PF02605.15 CBY37313.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI TMEM154 PF15102.6 CBY37313.1 - 0.18 11.7 3.5 0.18 11.7 2.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family TMEM52 PF14979.6 CBY37313.1 - 0.29 11.1 6.0 0.81 9.6 6.0 1.9 1 1 0 1 1 1 0 Transmembrane 52 NYAP_C PF15452.6 CBY37313.1 - 0.5 10.2 7.7 0.11 12.3 1.5 2.1 1 1 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter LRR_8 PF13855.6 CBY37314.1 - 1.1e-50 169.2 48.6 1.5e-17 63.1 1.1 6.7 3 3 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 CBY37314.1 - 4.6e-25 87.3 33.7 4.8e-06 26.8 1.1 7.3 2 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY37314.1 - 2.3e-23 82.5 7.5 3.4e-11 43.2 0.2 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY37314.1 - 1.8e-18 66.6 15.8 5.7e-08 32.5 2.3 4.3 2 2 2 4 4 4 3 Leucine-rich repeat I-set PF07679.16 CBY37314.1 - 3.4e-15 55.9 0.0 5.7e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY37314.1 - 2e-11 44.3 0.0 4.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 CBY37314.1 - 6.2e-09 35.2 32.7 0.42 11.3 0.1 11.0 11 0 0 11 11 11 3 Leucine Rich Repeat ig PF00047.25 CBY37314.1 - 7.7e-09 35.6 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain LRRNT PF01462.18 CBY37314.1 - 8.1e-09 34.9 9.8 0.00057 19.5 0.7 2.6 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain Ig_2 PF13895.6 CBY37314.1 - 0.00049 20.4 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain LRRCT PF01463.24 CBY37314.1 - 0.0053 17.2 1.0 4.8 8.0 0.0 3.4 3 0 0 3 3 2 1 Leucine rich repeat C-terminal domain LRR_6 PF13516.6 CBY37314.1 - 0.0071 16.3 22.1 1.6 9.0 0.2 8.2 8 0 0 8 8 8 2 Leucine Rich repeat V-set PF07686.17 CBY37314.1 - 0.046 13.9 0.0 0.22 11.7 0.0 2.1 1 1 0 1 1 1 0 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY37314.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF4588 PF15251.6 CBY37315.1 - 9.5e-16 58.3 7.3 2.3e-15 57.0 7.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Spectrin_like PF18373.1 CBY37315.1 - 0.067 13.3 0.6 1.6 8.9 0.3 2.8 2 1 1 3 3 3 0 Spectrin like domain Uds1 PF15456.6 CBY37315.1 - 0.21 11.7 4.4 0.74 10.0 4.4 2.0 1 1 0 1 1 1 0 Up-regulated During Septation CREPT PF16566.5 CBY37315.1 - 0.24 11.5 2.3 0.49 10.6 2.3 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SH3_9 PF14604.6 CBY37316.1 - 2.5e-06 27.3 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY37316.1 - 1.5e-05 24.5 0.2 3.4e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 SH3 domain DUF4064 PF13273.6 CBY37316.1 - 8.3e-05 22.8 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) RseC_MucC PF04246.12 CBY37316.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC SH3_2 PF07653.17 CBY37316.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain DUF4834 PF16118.5 CBY37316.1 - 0.1 13.6 1.8 0.32 12.0 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) G0-G1_switch_2 PF15103.6 CBY37316.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 LapA_dom PF06305.11 CBY37316.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain OAD_gamma PF04277.13 CBY37316.1 - 0.15 12.6 0.0 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Arm PF00514.23 CBY37317.1 - 4.5e-37 125.0 25.3 5.7e-10 38.9 0.0 9.6 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBY37317.1 - 2.5e-14 53.6 2.9 0.019 15.0 0.1 5.1 2 1 3 5 5 5 5 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY37317.1 - 3.3e-14 53.0 10.7 0.001 19.4 0.7 5.9 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.22 CBY37317.1 - 4.8e-14 51.3 8.5 0.11 12.9 0.1 7.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 CBY37317.1 - 1e-09 38.7 22.2 0.00073 20.0 1.0 6.8 6 2 3 9 9 7 5 HEAT-like repeat Adaptin_N PF01602.20 CBY37317.1 - 2.7e-08 32.8 9.1 0.002 16.8 1.6 3.5 1 1 1 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.11 CBY37317.1 - 3.2e-07 30.3 0.2 2.2 8.0 0.0 4.0 2 1 0 3 3 3 3 DNA alkylation repair enzyme CHASE6_C PF17150.4 CBY37317.1 - 6.3e-07 30.0 2.7 1.1 9.9 0.1 6.6 6 3 2 8 8 8 1 C-terminal domain of two-partite extracellular sensor domain RICTOR_V PF14668.6 CBY37317.1 - 3.3e-06 27.2 0.1 1.6 9.0 0.0 4.4 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.6 CBY37317.1 - 0.00015 20.9 3.3 0.0011 18.0 1.0 3.0 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Proteasom_PSMB PF10508.9 CBY37317.1 - 0.00016 20.3 6.1 0.0096 14.5 1.1 3.2 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.8 CBY37317.1 - 0.00044 20.3 1.8 0.86 9.7 0.0 4.1 4 0 0 4 4 4 1 V-ATPase subunit H Mo25 PF08569.11 CBY37317.1 - 0.00093 18.6 2.5 0.096 12.0 0.2 2.8 2 1 1 3 3 3 2 Mo25-like Arm_2 PF04826.13 CBY37317.1 - 0.0028 17.2 0.8 2.7 7.4 0.0 3.8 1 1 3 4 4 4 1 Armadillo-like HEAT_PBS PF03130.16 CBY37317.1 - 0.0032 18.0 6.5 4.7 8.2 0.3 5.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat API5 PF05918.11 CBY37317.1 - 0.0064 15.4 6.6 0.9 8.3 0.3 3.9 2 1 1 4 4 4 2 Apoptosis inhibitory protein 5 (API5) DUF3731 PF12531.8 CBY37317.1 - 0.028 14.2 4.5 17 5.1 0.1 3.4 3 1 0 3 3 3 0 DNA-K related protein COMMD1_N PF17221.3 CBY37317.1 - 0.094 13.0 0.6 7.6 6.9 0.0 3.2 3 0 0 3 3 3 0 COMMD1 N-terminal domain MMS19_C PF12460.8 CBY37317.1 - 0.21 10.7 9.4 0.57 9.2 0.4 3.7 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Ras PF00071.22 CBY37318.1 - 4.9e-47 159.5 0.5 6.3e-47 159.2 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37318.1 - 2.5e-35 121.3 0.2 3.1e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37318.1 - 1.4e-13 50.7 0.3 1.9e-13 50.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY37318.1 - 0.0002 21.4 0.1 0.00028 21.0 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY37318.1 - 0.00025 20.5 0.1 0.00034 20.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBY37318.1 - 0.00049 19.7 0.2 0.0014 18.2 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY37318.1 - 0.0012 18.2 0.1 0.0016 17.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ICE2 PF08426.10 CBY37321.1 - 0.014 14.5 0.6 0.023 13.8 0.6 1.2 1 0 0 1 1 1 0 ICE2 Ntox4 PF15541.6 CBY37321.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 4 PLAT PF01477.23 CBY37322.1 - 4.5e-19 69.1 0.4 5.5e-19 68.9 0.4 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain Glyco_hydro_125 PF06824.11 CBY37323.1 - 0.032 13.1 0.1 0.25 10.2 0.0 2.1 2 0 0 2 2 2 0 Metal-independent alpha-mannosidase (GH125) Yuri_gagarin PF15934.5 CBY37324.1 - 0.0036 17.2 0.5 0.0037 17.1 0.5 1.1 1 0 0 1 1 1 1 Yuri gagarin APG17 PF04108.12 CBY37324.1 - 0.0066 15.6 0.8 0.0079 15.4 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 B PF02216.16 CBY37324.1 - 0.041 13.9 1.6 0.065 13.2 1.3 1.5 1 1 0 1 1 1 0 B domain DUF1640 PF07798.11 CBY37324.1 - 0.058 13.5 3.9 0.076 13.1 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF573 PF04504.14 CBY37324.1 - 0.06 14.0 0.9 0.12 13.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF573 N1221 PF07923.13 CBY37324.1 - 0.063 12.5 0.9 0.11 11.7 0.7 1.5 1 1 1 2 2 2 0 N1221-like protein Ribosomal_L10 PF00466.20 CBY37324.1 - 0.14 12.3 1.7 0.17 12.0 0.9 1.8 1 1 1 2 2 2 0 Ribosomal protein L10 zf-CCHC_4 PF14392.6 CBY37324.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4404 PF14357.6 CBY37324.1 - 0.39 11.4 4.0 6.8 7.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) CHD5 PF04420.14 CBY37324.1 - 0.88 9.4 3.4 1.4 8.8 3.4 1.5 1 1 0 1 1 1 0 CHD5-like protein Lectin_C PF00059.21 CBY37325.1 - 1.3e-42 144.9 24.3 7.1e-20 71.8 0.4 5.0 4 1 0 4 4 4 3 Lectin C-type domain UL45 PF05473.12 CBY37325.1 - 3.5e-11 43.1 9.7 6.6e-06 25.9 0.0 4.1 4 1 0 4 4 4 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 CBY37325.1 - 0.058 12.7 0.6 0.31 10.3 0.2 2.2 2 0 0 2 2 2 0 Chordopoxvirus A33R protein MH2 PF03166.14 CBY37328.1 - 6.9e-54 182.9 0.3 1e-53 182.3 0.3 1.3 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY37328.1 - 1.4e-30 105.6 1.7 2.4e-30 104.8 1.7 1.4 1 0 0 1 1 1 1 MH1 domain Ras PF00071.22 CBY37329.1 - 1.6e-17 63.6 0.0 2.3e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBY37329.1 - 1.7e-13 50.9 0.1 1.7e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37329.1 - 9e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 CBY37329.1 - 0.0062 16.8 0.1 0.61 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 CBY37329.1 - 0.0092 15.4 0.1 0.014 14.8 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY37329.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 CBY37329.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CBY37329.1 - 0.042 13.6 0.1 0.14 11.9 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CBY37329.1 - 0.051 14.1 0.2 0.13 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBY37329.1 - 0.094 12.0 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 CBY37329.1 - 0.11 12.8 0.2 0.19 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CBY37329.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA helicase Glyco_transf_25 PF01755.17 CBY37331.1 - 7.7e-25 87.9 0.0 4.1e-23 82.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_4 PF13704.6 CBY37331.1 - 1e-09 38.8 0.4 3e-09 37.3 0.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 CBY37331.1 - 2.5e-06 27.1 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CBY37331.1 - 0.00051 19.9 0.1 0.076 12.8 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 DUF4302 PF14135.6 CBY37333.1 - 0.027 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Pkinase_Tyr PF07714.17 CBY37334.1 - 3.6e-41 141.2 0.0 1e-37 129.9 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY37334.1 - 6.8e-28 97.8 0.8 1.7e-24 86.6 0.0 3.0 2 1 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 CBY37334.1 - 0.0054 16.1 0.1 0.0085 15.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY37334.1 - 0.056 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinesin PF00225.23 CBY37334.1 - 0.12 11.2 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Kinesin motor domain OATP PF03137.20 CBY37335.1 - 0.0045 15.3 0.8 0.0046 15.3 0.8 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Transgly_assoc PF04226.13 CBY37335.1 - 0.0084 16.3 0.2 0.014 15.7 0.2 1.4 1 0 0 1 1 1 1 Transglycosylase associated protein MFS_1 PF07690.16 CBY37336.1 - 1.1e-19 70.7 11.5 1.3e-19 70.4 11.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY37336.1 - 0.014 14.3 6.1 0.011 14.6 3.7 1.8 1 1 1 2 2 2 0 MFS_1 like family DUF4567 PF15131.6 CBY37336.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) SIR2 PF02146.17 CBY37337.1 - 9.1e-50 169.0 0.0 1.1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Zn_Tnp_IS91 PF14319.6 CBY37337.1 - 0.11 12.6 1.0 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF1168 PF06658.12 CBY37338.1 - 1.2e-30 106.1 22.6 2.2e-30 105.3 22.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DDHD PF02862.17 CBY37338.1 - 0.093 12.9 6.4 0.13 12.4 6.4 1.2 1 0 0 1 1 1 0 DDHD domain Dsh_C PF12316.8 CBY37338.1 - 0.15 12.4 5.3 0.2 12.1 5.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Spore_coat_CotO PF14153.6 CBY37338.1 - 0.38 10.7 18.3 0.19 11.6 16.0 1.7 2 0 0 2 2 2 0 Spore coat protein CotO SAPS PF04499.15 CBY37338.1 - 0.56 8.9 13.9 0.77 8.5 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 CBY37338.1 - 0.95 7.3 6.0 0.96 7.3 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 CBY37338.1 - 1.7 8.4 15.4 2.6 7.8 15.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CBY37338.1 - 1.8 5.6 6.3 1.8 5.6 6.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2981 PF11200.8 CBY37338.1 - 1.9 8.2 4.4 1.9 8.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Hid1 PF12722.7 CBY37338.1 - 2.1 6.3 8.9 2.2 6.3 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.12 CBY37338.1 - 2.4 6.0 8.8 3.8 5.4 8.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4746 PF15928.5 CBY37338.1 - 4.8 6.5 16.4 8.1 5.8 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 CBY37338.1 - 8.9 5.6 10.9 11 5.2 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 CBY37340.1 - 6e-10 39.3 7.3 1.1e-09 38.4 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY37340.1 - 1.8e-07 31.0 3.4 3.3e-07 30.2 2.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY37340.1 - 2.3e-07 30.6 8.0 6.6e-07 29.1 8.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY37340.1 - 6.7e-07 29.2 7.9 1.4e-06 28.1 7.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY37340.1 - 6.9e-07 29.0 9.0 1.5e-06 28.0 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY37340.1 - 6.9e-06 26.0 2.6 1.3e-05 25.1 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBY37340.1 - 8.4e-06 26.0 5.7 2.5e-05 24.5 5.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBY37340.1 - 1.4e-05 25.2 4.8 1.4e-05 25.2 4.8 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY37340.1 - 1.4e-05 24.8 6.3 3.3e-05 23.6 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY37340.1 - 4e-05 23.3 6.6 8e-05 22.3 6.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CBY37340.1 - 0.0017 18.2 2.7 0.0017 18.2 2.7 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY37340.1 - 0.0059 16.5 10.6 0.018 14.9 10.7 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBY37340.1 - 0.0075 15.9 5.6 0.017 14.7 5.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBY37340.1 - 0.13 12.1 2.3 0.29 10.9 2.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger FlxA PF14282.6 CBY37340.1 - 0.95 9.5 25.5 2.6 8.1 6.4 4.2 2 1 2 4 4 4 0 FlxA-like protein FYVE PF01363.21 CBY37340.1 - 1.1 9.5 9.5 4.7 7.4 9.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger LMBR1 PF04791.16 CBY37340.1 - 4.2 6.2 14.8 6.3 5.6 14.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 CBY37340.1 - 9.5 6.8 42.0 20 5.7 0.5 5.5 2 1 1 3 3 3 0 Cell division protein ZapB HEAT_EZ PF13513.6 CBY37341.1 - 0.048 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 HEAT-like repeat XRCC4 PF06632.12 CBY37341.1 - 0.083 11.7 0.3 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Troponin PF00992.20 CBY37342.1 - 1.6e-37 128.8 6.3 1.9e-37 128.6 6.3 1.1 1 0 0 1 1 1 1 Troponin Maelstrom PF13017.6 CBY37342.1 - 0.0025 17.5 0.3 0.0031 17.2 0.3 1.1 1 0 0 1 1 1 1 piRNA pathway germ-plasm component SAP PF02037.27 CBY37342.1 - 0.0027 17.4 2.5 0.45 10.3 0.0 3.4 3 0 0 3 3 3 2 SAP domain DUF4600 PF15372.6 CBY37342.1 - 0.02 15.3 2.9 0.063 13.7 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) GCN5L1 PF06320.13 CBY37342.1 - 0.025 14.7 0.3 0.19 11.9 0.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Jnk-SapK_ap_N PF09744.9 CBY37342.1 - 0.063 13.5 2.1 0.13 12.5 2.1 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 STAT_alpha PF01017.20 CBY37342.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain SLATT_fungal PF18142.1 CBY37342.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Phospholip_A2_1 PF00068.19 CBY37344.1 - 2.7e-17 63.2 9.8 5.4e-17 62.3 9.8 1.5 1 0 0 1 1 1 1 Phospholipase A2 MFS_1 PF07690.16 CBY37346.1 - 7.8e-09 34.9 11.0 1.3e-08 34.2 11.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.19 CBY37346.1 - 0.017 15.1 0.4 0.049 13.7 0.2 1.8 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain B_solenoid_ydck PF18836.1 CBY37346.1 - 0.027 14.3 0.1 7.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK Glutaredoxin PF00462.24 CBY37348.1 - 9.5e-13 48.2 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin NUDIX PF00293.28 CBY37348.1 - 1.9e-07 31.2 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA_12 PF13087.6 CBY37349.1 - 1.9e-46 158.3 0.0 4.7e-46 156.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBY37349.1 - 2e-06 27.8 0.3 1.6e-05 24.8 0.2 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CBY37349.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain YhfT PF10797.9 CBY37349.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function PRP1_N PF06424.12 CBY37349.1 - 9.5 6.6 7.0 8.4 6.8 1.8 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF1548 PF07579.11 CBY37350.1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) DUF2120 PF09893.9 CBY37350.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) HSP70 PF00012.20 CBY37352.1 - 4e-25 88.1 0.1 4.3e-25 88.0 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein AnmK PF03702.14 CBY37352.1 - 0.008 15.3 0.0 0.0087 15.2 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FDX-ACB PF03147.14 CBY37352.1 - 0.13 12.7 0.1 0.22 12.0 0.0 1.4 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Pkinase PF00069.25 CBY37353.1 - 8.1e-27 94.2 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37353.1 - 8e-12 45.0 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY37353.1 - 3.8e-06 25.9 0.1 4.8e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY37353.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBY37353.1 - 0.057 13.3 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY37353.1 - 0.14 11.4 0.0 0.75 9.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DUF588 PF04535.12 CBY37354.1 - 0.0074 16.1 1.6 0.012 15.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Tetraspanin PF00335.20 CBY37354.1 - 5 6.8 9.5 0.4 10.4 4.3 1.7 1 1 0 1 1 1 0 Tetraspanin family Lectin_C PF00059.21 CBY37355.1 - 2.5e-17 63.5 0.2 6e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Phospholip_A2_1 PF00068.19 CBY37356.1 - 3.6e-15 56.4 4.5 8.3e-15 55.2 4.5 1.5 1 0 0 1 1 1 1 Phospholipase A2 EB PF01683.18 CBY37356.1 - 0.48 10.8 5.5 0.84 10.0 0.6 2.6 2 0 0 2 2 2 0 EB module Tmemb_9 PF05434.11 CBY37357.1 - 0.00072 19.5 1.2 0.11 12.4 0.6 2.4 2 0 0 2 2 2 2 TMEM9 Synaptobrevin PF00957.21 CBY37357.1 - 0.0016 18.2 4.2 0.004 16.9 4.2 1.7 1 0 0 1 1 1 1 Synaptobrevin DUF3976 PF13121.6 CBY37357.1 - 0.032 14.4 3.3 0.05 13.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) Aa_trans PF01490.18 CBY37358.1 - 3.3e-66 223.7 25.3 4.4e-53 180.4 10.8 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein MARVEL PF01284.23 CBY37358.1 - 0.0056 16.7 1.1 0.0056 16.7 1.1 3.5 1 1 2 4 4 4 1 Membrane-associating domain DUF2427 PF10348.9 CBY37358.1 - 4.7 7.1 10.5 1.7 8.5 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) Fibrinogen_C PF00147.18 CBY37359.1 - 4.8e-05 23.3 0.2 9.3e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF4803 PF16061.5 CBY37359.1 - 0.0047 16.4 0.5 0.0047 16.4 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4803) Apolipoprotein PF01442.18 CBY37359.1 - 0.0066 16.3 4.2 0.11 12.3 0.4 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain OmpH PF03938.14 CBY37359.1 - 0.39 11.0 8.4 0.088 13.2 1.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 CBY37359.1 - 0.48 10.6 6.3 0.066 13.4 1.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 CBY37359.1 - 0.73 9.8 4.8 0.37 10.8 2.0 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p IFT57 PF10498.9 CBY37359.1 - 1.6 7.6 7.6 6.1 5.7 7.6 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CUB PF00431.20 CBY37360.1 - 1.3e-07 31.9 1.1 2e-07 31.3 0.8 1.4 1 1 0 1 1 1 1 CUB domain BNR PF02012.20 CBY37360.1 - 0.043 13.8 0.2 0.21 11.7 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat IF-2B PF01008.17 CBY37361.1 - 1.1e-25 90.4 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.23 CBY37361.1 - 0.01 15.5 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain OATP PF03137.20 CBY37362.1 - 1.7e-23 82.7 0.1 2.7e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AAA_11 PF13086.6 CBY37363.1 - 2.4e-11 43.9 0.2 2.4e-11 43.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBY37363.1 - 2.6e-08 34.3 0.0 4.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBY37363.1 - 4.3e-06 26.6 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBY37363.1 - 0.00031 20.8 1.1 0.0041 17.1 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CBY37363.1 - 0.0014 18.1 0.0 0.0039 16.7 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 CBY37363.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 CBY37363.1 - 0.0079 16.6 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY37363.1 - 0.0085 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CBY37363.1 - 0.024 15.1 0.2 0.1 13.0 0.2 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CBY37363.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CBY37363.1 - 0.058 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CBY37363.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 CBY37363.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FoP_duplication PF13865.6 CBY37363.1 - 6.7 7.3 9.3 17 6.0 9.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Myosin_head PF00063.21 CBY37364.1 - 6.4e-262 870.7 0.0 6.4e-262 870.7 0.0 2.2 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY37364.1 - 1.3e-138 463.7 260.6 1.3e-138 463.7 260.6 1.4 2 0 0 2 2 2 1 Myosin tail AAA_22 PF13401.6 CBY37364.1 - 0.099 12.9 0.0 0.099 12.9 0.0 5.0 4 2 0 4 4 4 0 AAA domain AAA_16 PF13191.6 CBY37364.1 - 1.8 8.9 0.0 1.8 8.9 0.0 5.1 4 1 1 5 5 5 0 AAA ATPase domain zf-H2C2_2 PF13465.6 CBY37365.1 - 9.8e-20 70.0 44.8 5.3e-08 32.9 4.8 6.2 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY37365.1 - 2.1e-17 62.5 44.4 6.5e-06 26.3 1.9 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37365.1 - 3.1e-11 43.1 42.4 0.00068 20.3 1.5 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY37365.1 - 8.2e-11 41.9 29.0 0.034 14.4 0.2 5.4 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY37365.1 - 7.5e-08 32.5 31.4 0.017 15.5 0.2 5.4 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CBY37365.1 - 0.031 14.7 29.5 0.41 11.1 0.2 5.8 2 1 3 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2180 PF09947.9 CBY37365.1 - 0.055 13.4 0.5 0.055 13.4 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.7 CBY37365.1 - 0.19 12.0 29.9 5.7 7.3 0.8 5.2 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY37365.1 - 0.87 9.7 41.0 0.27 11.3 3.3 5.5 5 1 0 5 5 5 0 C2H2-type zinc finger PHF5 PF03660.14 CBY37365.1 - 1.8 8.8 7.2 0.6 10.3 3.2 2.2 2 1 1 3 3 3 0 PHF5-like protein zf-C2H2_jaz PF12171.8 CBY37366.1 - 0.01 16.1 0.6 0.017 15.4 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY37366.1 - 0.18 12.2 0.3 0.31 11.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY37367.1 - 0.0024 18.1 0.3 0.0024 18.1 0.3 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 CBY37367.1 - 0.003 18.0 0.8 0.46 10.9 0.1 2.1 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 CBY37367.1 - 0.012 15.9 0.1 0.012 15.9 0.1 1.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met2 PF12907.7 CBY37367.1 - 0.045 13.9 2.1 1.3 9.2 0.2 2.5 2 1 0 2 2 2 0 Zinc-binding zf-met PF12874.7 CBY37367.1 - 0.057 13.8 2.1 1.7 9.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY37367.1 - 0.064 14.1 0.5 0.064 14.1 0.5 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY37367.1 - 5.2 7.7 11.8 4.9 7.8 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Atx10homo_assoc PF09759.9 CBY37368.1 - 0.03 14.3 0.1 0.15 12.1 0.1 2.3 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain PPV_E1_N PF00524.18 CBY37368.1 - 0.18 12.2 1.5 2.3 8.7 0.2 2.4 2 0 0 2 2 2 0 E1 Protein, N terminal domain WD40 PF00400.32 CBY37369.1 - 3.2e-38 129.0 11.5 2.5e-09 37.6 0.0 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37369.1 - 3.3e-13 49.7 0.1 1.2e-05 25.5 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY37369.1 - 0.00018 21.4 0.0 0.021 14.7 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBY37369.1 - 0.019 13.9 0.0 9.5 5.1 0.0 3.3 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY37369.1 - 0.028 13.1 0.0 2.3 6.7 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CBY37369.1 - 0.18 11.1 0.0 16 4.7 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain UDPGP PF01704.18 CBY37371.1 - 3.6e-183 608.9 1.3 4.3e-183 608.6 1.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 CBY37371.1 - 0.02 13.7 0.2 2 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) FG-GAP_2 PF14312.6 CBY37371.1 - 0.27 11.5 0.5 0.57 10.5 0.5 1.4 1 0 0 1 1 1 0 FG-GAP repeat Sulfotransfer_2 PF03567.14 CBY37372.1 - 1.3e-43 149.7 4.4 1.8e-43 149.3 4.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family zf-H2C2_2 PF13465.6 CBY37373.1 - 1.7e-18 66.1 21.7 2.4e-08 34.0 1.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY37373.1 - 7e-16 57.7 17.5 1.5e-05 25.2 1.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37373.1 - 4.1e-10 39.6 17.4 0.00068 20.3 1.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY37373.1 - 5.6e-07 29.4 15.8 0.006 16.6 2.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY37373.1 - 6.3e-06 26.4 8.3 4e-05 23.8 0.9 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-MYST PF17772.1 CBY37373.1 - 0.0036 16.9 3.2 0.21 11.2 0.1 2.8 2 1 1 3 3 3 1 MYST family zinc finger domain C1_4 PF07975.12 CBY37373.1 - 0.005 17.1 3.1 3.9 7.8 2.3 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain OSTMP1 PF09777.9 CBY37373.1 - 0.019 14.4 0.9 0.032 13.6 0.9 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor SEO_N PF14576.6 CBY37373.1 - 0.076 12.2 0.2 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Sieve element occlusion N-terminus Scramblase PF03803.15 CBY37373.1 - 0.12 11.6 0.2 0.27 10.5 0.2 1.5 1 1 1 2 2 2 0 Scramblase Zn-ribbon_8 PF09723.10 CBY37373.1 - 0.15 12.2 4.5 5 7.3 1.5 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 CBY37373.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY37373.1 - 0.33 11.3 10.4 1.4 9.2 1.5 2.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY37373.1 - 0.45 10.9 11.5 0.32 11.4 1.0 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2757 PF10955.8 CBY37373.1 - 1.7 9.0 4.1 3.6 7.9 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) Mut7-C PF01927.16 CBY37373.1 - 1.8 8.6 4.8 19 5.3 4.8 2.2 1 1 0 1 1 1 0 Mut7-C RNAse domain zf_UBZ PF18439.1 CBY37373.1 - 2.5 7.8 7.2 5.4 6.7 0.2 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PHD PF00628.29 CBY37373.1 - 2.6 8.0 8.9 9.3 6.2 2.5 2.4 1 1 1 2 2 2 0 PHD-finger zf-C2H2_11 PF16622.5 CBY37373.1 - 3.6 7.4 16.3 0.96 9.3 0.9 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HE PF16278.5 CBY37373.1 - 3.7 8.1 17.5 50 4.5 8.7 3.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 CBY37373.1 - 3.8 7.2 6.3 1.5 8.6 2.1 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain eIF_4EBP PF05456.11 CBY37374.1 - 0.067 13.1 0.7 0.11 12.5 0.5 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Cyclin_N PF00134.23 CBY37375.1 - 4.3e-18 65.3 0.1 2.6e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3456 PF11938.8 CBY37375.1 - 0.081 13.4 0.2 0.2 12.1 0.2 1.7 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP PFK PF00365.20 CBY37376.1 - 7.5e-178 589.8 7.3 2.4e-96 322.4 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Hist_deacetyl PF00850.19 CBY37377.1 - 2.4e-68 230.9 0.0 3.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Trypsin PF00089.26 CBY37380.1 - 7.7e-15 55.3 0.6 2.4e-13 50.4 0.0 2.9 2 1 0 2 2 2 1 Trypsin Qua1 PF16274.5 CBY37380.1 - 0.06 13.2 1.0 14 5.6 0.1 2.9 2 0 0 2 2 2 0 Qua1 domain G-7-MTase PF12803.7 CBY37381.1 - 0.01 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DSPc PF00782.20 CBY37382.1 - 7.5e-35 119.6 0.8 1.7e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEK_C PF08766.11 CBY37382.1 - 2.1e-07 30.7 1.2 5.8e-07 29.3 1.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain Y_phosphatase PF00102.27 CBY37382.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase L51_S25_CI-B8 PF05047.16 CBY37383.1 - 5.9e-15 54.9 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1894 PF08979.11 CBY37383.1 - 0.081 13.3 0.0 0.49 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) Rep_N PF08724.10 CBY37383.1 - 0.2 11.4 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Rep protein catalytic domain like HlyIII PF03006.20 CBY37384.1 - 2e-69 233.7 21.2 2.4e-69 233.5 21.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Myb_DNA-binding PF00249.31 CBY37386.1 - 0.014 15.6 0.1 0.068 13.4 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY37386.1 - 0.041 13.8 1.0 0.13 12.2 1.0 1.9 1 0 0 1 1 1 0 Myb DNA-binding like DUF2894 PF11445.8 CBY37386.1 - 0.22 12.0 3.0 0.4 11.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Pox_VLTF3 PF04947.14 CBY37387.1 - 0.089 12.5 7.0 0.24 11.1 2.8 2.3 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Q_salvage PF10343.9 CBY37387.1 - 0.19 11.3 3.8 0.23 11.0 0.3 1.9 1 1 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Tam41_Mmp37 PF09139.11 CBY37387.1 - 0.31 10.5 4.5 0.22 10.9 2.5 1.6 1 1 1 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial fn3 PF00041.21 CBY37388.1 - 0.00017 21.8 0.4 0.0025 18.1 0.1 2.9 3 0 0 3 3 3 1 Fibronectin type III domain Stealth_CR2 PF11380.8 CBY37388.1 - 0.007 16.5 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 ABC2_membrane_2 PF12679.7 CBY37388.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Trypsin PF00089.26 CBY37389.1 - 6e-50 170.1 0.2 1.5e-49 168.8 0.2 1.7 1 1 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY37389.1 - 1.4e-30 105.5 20.6 1.3e-18 67.0 8.2 2.5 2 0 0 2 2 2 2 Kringle domain Trypsin_2 PF13365.6 CBY37389.1 - 0.0034 18.3 0.0 0.0064 17.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Toxin_5 PF05294.13 CBY37389.1 - 6.8 7.2 8.4 25 5.4 0.4 3.6 3 0 0 3 3 3 0 Scorpion short toxin GPS PF01825.21 CBY37391.1 - 2.6e-08 34.3 5.6 2.6e-08 34.3 5.6 3.3 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif 7tm_2 PF00002.24 CBY37391.1 - 2.6e-05 23.6 1.0 4.2e-05 23.0 1.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DHDPS PF00701.22 CBY37393.1 - 2.7e-42 144.5 0.0 3.1e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Mistic PF11458.8 CBY37393.1 - 0.15 12.0 0.0 0.6 10.1 0.0 2.0 1 0 0 1 1 1 0 Membrane-integrating protein Mistic ETRAMP PF09716.10 CBY37394.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) ATP-gua_Ptrans PF00217.19 CBY37395.1 - 8.4e-65 218.2 0.0 1.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY37395.1 - 2.5e-24 85.4 0.0 4.8e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain DUF840 PF05801.11 CBY37395.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) SL4P PF17618.2 CBY37395.1 - 0.05 13.6 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein zf-H2C2_2 PF13465.6 CBY37396.1 - 9.3e-19 66.9 30.9 2.7e-09 37.0 1.1 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY37396.1 - 2.5e-18 65.4 32.3 3.4e-06 27.2 2.6 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37396.1 - 4.5e-14 51.9 30.2 0.00085 20.0 2.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY37396.1 - 4.2e-07 30.2 16.9 1.3e-05 25.3 5.5 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CBY37396.1 - 8.8e-05 22.4 26.0 0.035 14.1 3.6 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY37396.1 - 0.00046 19.9 16.3 0.0023 17.6 0.3 4.0 4 0 0 4 4 4 2 zinc-finger C2H2-type BolA PF01722.18 CBY37396.1 - 0.0028 17.9 4.8 0.21 11.9 2.1 2.7 2 1 0 2 2 2 1 BolA-like protein zf_UBZ PF18439.1 CBY37396.1 - 0.0075 15.8 9.5 0.29 10.8 0.7 3.1 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CBY37396.1 - 0.0077 16.5 20.4 1.7 9.0 2.2 4.5 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 CBY37396.1 - 0.12 12.6 2.6 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain ADK_lid PF05191.14 CBY37396.1 - 0.3 11.1 4.3 8.1 6.5 4.3 2.6 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2_aberr PF17017.5 CBY37396.1 - 1.3 9.2 13.5 1.2 9.2 0.7 2.6 1 1 1 2 2 2 0 Aberrant zinc-finger Zn-ribbon_8 PF09723.10 CBY37396.1 - 1.8 8.7 14.2 3.5 7.8 4.0 3.0 1 1 2 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 CBY37396.1 - 4 7.4 12.2 0.56 10.2 0.5 3.4 2 1 0 2 2 2 0 zinc-ribbon domain PIN_6 PF17146.4 CBY37397.1 - 1.1e-30 106.0 0.1 2e-30 105.2 0.1 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CBY37397.1 - 0.013 15.7 0.6 0.025 14.7 0.6 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Ntox1 PF15500.6 CBY37397.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Golgin_A5 PF09787.9 CBY37398.1 - 0.0034 16.9 9.7 0.005 16.3 9.7 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 MMTV_SAg PF01054.17 CBY37398.1 - 0.02 14.5 1.1 0.031 13.8 1.1 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen FANCAA PF15146.6 CBY37398.1 - 0.025 13.7 0.5 0.032 13.3 0.5 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated LRS4 PF10422.9 CBY37398.1 - 0.076 12.6 14.2 0.06 12.9 12.6 1.6 1 1 1 2 2 2 0 Monopolin complex subunit LRS4 Jnk-SapK_ap_N PF09744.9 CBY37398.1 - 0.15 12.3 17.0 0.07 13.3 14.7 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3573 PF12097.8 CBY37398.1 - 0.22 10.3 2.5 0.33 9.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.19 CBY37398.1 - 0.79 7.6 8.6 0.91 7.4 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CBY37398.1 - 2.7 8.5 18.0 5.4 7.6 18.0 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 CBY37398.1 - 3.2 6.5 13.6 4.9 5.9 13.6 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Uso1_p115_C PF04871.13 CBY37398.1 - 3.2 8.1 17.0 2.5 8.5 15.0 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MPM1 PF17234.2 CBY37398.1 - 5 7.4 10.4 8 6.7 10.4 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TMPIT PF07851.13 CBY37398.1 - 9.3 5.4 9.2 13 4.9 9.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF5027 PF16430.5 CBY37400.1 - 0.07 12.9 0.4 0.12 12.1 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5027) Gln-synt_C PF00120.24 CBY37401.1 - 1.5e-18 66.9 0.0 5.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CBY37401.1 - 1.4e-13 50.4 0.0 2.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PHD_like PF12910.7 CBY37401.1 - 0.047 13.7 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system DZR PF12773.7 CBY37402.1 - 3.7 7.6 23.7 0.3 11.1 13.1 3.6 3 1 0 3 3 3 0 Double zinc ribbon Peptidase_M18 PF02127.15 CBY37403.1 - 9.8e-64 215.7 0.0 1.2e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SPATA48 PF15073.6 CBY37406.1 - 1.5e-06 28.5 0.9 3.5e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Pkinase PF00069.25 CBY37408.1 - 7.9e-45 153.3 0.0 9.9e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37408.1 - 2e-21 76.5 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY37408.1 - 1.3e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY37408.1 - 1.9e-05 23.8 0.5 2.9e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY37408.1 - 4e-05 23.7 0.2 0.00073 19.5 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY37408.1 - 5.9e-05 22.7 1.7 9.2e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBY37408.1 - 9.8e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY37408.1 - 0.0015 17.9 1.0 0.0026 17.2 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5492 PF17596.2 CBY37408.1 - 0.039 14.3 1.3 0.11 12.9 1.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) Kinase-PolyVal PF18762.1 CBY37408.1 - 0.12 12.3 0.4 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 CBY37408.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 wnt PF00110.19 CBY37409.1 - 1.6e-87 294.0 30.9 1.8e-87 293.8 30.9 1.0 1 0 0 1 1 1 1 wnt family Connexin PF00029.19 CBY37410.1 - 3.9e-48 164.2 4.3 5e-48 163.9 4.3 1.1 1 0 0 1 1 1 1 Connexin Cadherin PF00028.17 CBY37412.1 - 1.6e-28 99.0 0.0 5e-09 36.5 0.0 4.6 4 0 0 4 4 4 4 Cadherin domain Cadherin_2 PF08266.12 CBY37412.1 - 0.00021 21.0 0.0 3.4 7.6 0.0 3.5 3 0 0 3 3 3 2 Cadherin-like RSN1_TM PF13967.6 CBY37412.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Protocadherin PF08374.11 CBY37412.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Protocadherin DUF3637 PF12337.8 CBY37412.1 - 0.084 13.2 0.1 0.28 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) zf-C4 PF00105.18 CBY37413.1 - 1.5e-27 95.8 12.2 2.5e-27 95.1 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY37413.1 - 0.046 13.3 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor ADH_N PF08240.12 CBY37414.1 - 1.2e-19 70.1 0.0 4.9e-19 68.2 0.0 2.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBY37414.1 - 2.5e-17 63.1 0.1 5.1e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-Di19 PF05605.12 CBY37414.1 - 6.6e-08 32.7 54.3 0.00044 20.5 0.6 10.8 12 0 0 12 12 12 4 Drought induced 19 protein (Di19), zinc-binding Glu_dehyd_C PF16912.5 CBY37414.1 - 5.1e-06 26.1 0.1 1.2e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus zf-C2H2 PF00096.26 CBY37414.1 - 0.025 15.0 0.1 0.025 15.0 0.1 13.4 15 0 0 15 15 15 0 Zinc finger, C2H2 type AlaDh_PNT_C PF01262.21 CBY37414.1 - 0.035 13.4 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2_4 PF13894.6 CBY37414.1 - 0.042 14.7 0.2 0.042 14.7 0.2 16.4 17 0 0 17 17 17 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY37414.1 - 0.16 11.7 0.0 0.16 11.7 0.0 7.1 7 0 0 7 7 7 0 C2H2-type zinc-finger domain DNA_RNApol_7kD PF03604.13 CBY37414.1 - 1.6 8.5 9.3 1.4 8.6 0.1 4.3 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_13 PF09855.9 CBY37414.1 - 1.6 8.9 6.6 18 5.6 0.3 3.6 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2H2_11 PF16622.5 CBY37414.1 - 5.9 6.8 28.0 0.18 11.6 0.1 6.4 6 0 0 6 6 6 0 zinc-finger C2H2-type Sulfotransfer_1 PF00685.27 CBY37415.1 - 4.6e-19 68.9 0.2 9.5e-19 67.9 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY37415.1 - 1.6e-09 38.5 0.0 1.3e-06 29.0 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family DUF3131 PF11329.8 CBY37415.1 - 0.071 12.2 0.0 0.42 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3131) Shisa PF13908.6 CBY37416.1 - 5.1e-06 26.9 2.3 7.7e-06 26.3 2.3 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Prominin PF05478.11 CBY37416.1 - 0.02 12.9 2.0 0.029 12.4 2.0 1.2 1 0 0 1 1 1 0 Prominin DUF3827 PF12877.7 CBY37416.1 - 0.038 12.4 0.3 0.054 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EphA2_TM PF14575.6 CBY37416.1 - 0.048 14.5 0.0 0.079 13.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CBY37416.1 - 0.07 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family ECSCR PF15820.5 CBY37416.1 - 0.08 12.8 3.2 0.15 11.9 3.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 CBY37416.1 - 0.12 12.3 0.5 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Rifin DUF4006 PF13179.6 CBY37416.1 - 0.77 9.7 5.6 1.8 8.6 5.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) TMEM52 PF14979.6 CBY37416.1 - 3.7 7.5 6.2 9.1 6.2 3.6 2.1 2 0 0 2 2 2 0 Transmembrane 52 FAM163 PF15069.6 CBY37416.1 - 3.7 8.0 10.4 11 6.4 10.4 1.8 1 1 0 1 1 1 0 FAM163 family TSP_1 PF00090.19 CBY37418.1 - 2.4 8.5 13.1 0.8 10.0 8.1 2.4 2 0 0 2 2 2 0 Thrombospondin type 1 domain Glyco_hydro_1 PF00232.18 CBY37419.1 - 1.9e-136 455.1 4.5 2.4e-136 454.8 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SET PF00856.28 CBY37421.1 - 8.7e-15 55.5 0.0 1.2e-14 55.1 0.0 1.2 1 0 0 1 1 1 1 SET domain GTP_EFTU PF00009.27 CBY37424.1 - 5.6e-29 101.1 0.0 9.9e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY37424.1 - 8.5e-16 57.8 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBY37424.1 - 0.00024 21.1 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CBY37424.1 - 0.00025 20.9 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Asn_synthase PF00733.21 CBY37425.1 - 3.5e-22 79.6 0.0 4.7e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CBY37425.1 - 1.9e-13 50.4 0.0 5e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBY37425.1 - 6.9e-09 36.0 0.0 5.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain PDZ_1 PF12812.7 CBY37425.1 - 0.096 12.7 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 PDZ-like domain CBM_X2 PF03442.14 CBY37425.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Sushi PF00084.20 CBY37426.1 - 0.0051 17.4 17.5 0.035 14.7 2.6 3.5 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) LRR_8 PF13855.6 CBY37427.1 - 1.3e-31 108.1 21.9 2e-10 40.2 0.5 4.9 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 CBY37427.1 - 1.1e-14 54.5 0.1 6e-09 35.9 0.2 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY37427.1 - 4e-14 52.5 17.2 0.00092 19.6 1.0 6.3 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY37427.1 - 0.0065 16.9 14.3 13 6.8 0.6 7.6 8 2 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 CBY37427.1 - 0.015 14.8 5.1 0.2 11.1 0.7 2.6 1 1 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBY37427.1 - 3.4 8.0 16.9 32 4.9 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich repeat Spc7 PF08317.11 CBY37428.1 - 6.8e-07 28.5 47.5 0.0012 17.8 6.3 5.9 2 2 5 7 7 7 5 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 CBY37428.1 - 1.5e-06 28.5 23.3 0.00015 22.1 0.6 7.5 4 3 2 7 7 7 1 Snapin/Pallidin DUF1664 PF07889.12 CBY37428.1 - 2.9e-05 24.1 44.6 0.81 9.7 0.8 8.2 1 1 5 7 7 7 4 Protein of unknown function (DUF1664) C1q PF00386.21 CBY37428.1 - 8.1e-05 22.8 0.1 0.00023 21.4 0.1 1.8 1 0 0 1 1 1 1 C1q domain Baculo_PEP_C PF04513.12 CBY37428.1 - 0.00011 22.2 40.6 0.46 10.5 5.5 7.4 2 2 3 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CBY37428.1 - 0.0012 18.2 33.4 0.1 11.9 2.6 4.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CBY37428.1 - 0.0018 18.3 9.8 0.0018 18.3 9.8 7.3 2 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CBY37428.1 - 0.0027 18.1 41.6 0.0071 16.8 1.5 8.6 5 3 2 7 7 7 2 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 CBY37428.1 - 0.0031 17.7 34.2 2.4 8.5 0.2 8.4 4 4 4 8 8 8 2 Bacterial protein of unknown function (DUF948) CAP_N PF01213.19 CBY37428.1 - 0.0035 16.9 4.0 0.0035 16.9 4.0 3.7 4 0 0 4 4 4 1 Adenylate cyclase associated (CAP) N terminal BclA_C PF18573.1 CBY37428.1 - 0.0052 16.7 0.6 0.014 15.3 0.6 1.7 1 0 0 1 1 1 1 BclA C-terminal domain DUF5082 PF16888.5 CBY37428.1 - 0.0066 16.7 3.6 0.0066 16.7 3.6 7.5 2 2 6 8 8 7 1 Domain of unknown function (DUF5082) ATG16 PF08614.11 CBY37428.1 - 0.0082 16.4 9.8 0.0082 16.4 9.8 5.5 2 2 1 4 4 4 2 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 CBY37428.1 - 0.01 16.2 43.5 2.1 8.8 0.2 10.9 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) FliJ PF02050.16 CBY37428.1 - 0.012 15.8 0.1 0.012 15.8 0.1 5.7 4 3 1 5 5 5 0 Flagellar FliJ protein Tropomyosin_1 PF12718.7 CBY37428.1 - 0.047 13.8 48.4 0.033 14.3 1.6 7.0 2 2 3 6 6 6 0 Tropomyosin like Prominin PF05478.11 CBY37428.1 - 0.06 11.3 39.4 0.12 10.3 2.8 4.4 2 1 1 4 4 4 0 Prominin TolA_bind_tri PF16331.5 CBY37428.1 - 0.2 11.7 21.0 0.29 11.3 0.2 6.4 6 1 1 7 7 6 0 TolA binding protein trimerisation DUF4472 PF14739.6 CBY37428.1 - 0.32 11.8 32.2 1.1 10.0 2.4 6.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4472) Filament PF00038.21 CBY37428.1 - 0.4 10.2 47.2 2.6 7.6 1.2 6.2 2 2 2 4 4 4 0 Intermediate filament protein Laminin_II PF06009.12 CBY37428.1 - 0.62 10.1 43.8 2.7 8.0 4.6 7.3 4 3 5 9 9 9 0 Laminin Domain II eIF-5a PF01287.20 CBY37428.1 - 1.4 9.1 6.2 1.5 9.0 0.0 3.7 5 0 0 5 5 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Exonuc_VII_L PF02601.15 CBY37428.1 - 1.9 7.9 33.8 3 7.3 5.3 4.3 1 1 3 4 4 4 0 Exonuclease VII, large subunit Prefoldin PF02996.17 CBY37428.1 - 2.5 8.0 27.4 2.9 7.8 0.3 7.3 7 1 0 7 7 7 0 Prefoldin subunit Fib_alpha PF08702.10 CBY37428.1 - 2.7 8.2 42.0 1.9 8.6 0.4 7.1 4 4 2 7 7 7 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 CBY37428.1 - 2.7 8.1 18.4 1.2 9.2 0.2 5.9 7 1 0 7 7 7 0 bZIP transcription factor DUF2536 PF10750.9 CBY37428.1 - 2.9 7.9 5.4 0.74 9.8 0.3 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF2536) CorA PF01544.18 CBY37428.1 - 3.3 6.9 22.2 2.1 7.6 7.4 4.2 3 2 0 4 4 4 0 CorA-like Mg2+ transporter protein VSG_B PF13206.6 CBY37428.1 - 3.3 6.9 9.5 0.56 9.4 4.8 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain UPF0242 PF06785.11 CBY37428.1 - 4.8 7.2 41.9 1.7 8.7 8.2 5.5 3 3 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SMG1 PF15785.5 CBY37429.1 - 7e-75 252.7 0.1 1.9e-74 251.2 0.1 1.7 1 0 0 1 1 1 1 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 CBY37429.1 - 4.4e-48 164.3 0.0 1.8e-47 162.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 CBY37429.1 - 0.038 14.4 4.4 0.078 13.4 0.6 3.6 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain HEAT PF02985.22 CBY37429.1 - 0.069 13.4 0.0 0.53 10.7 0.0 2.6 3 0 0 3 3 3 0 HEAT repeat HTH_40 PF14493.6 CBY37429.1 - 0.1 13.0 2.5 31 5.1 0.0 3.6 2 1 1 3 3 3 0 Helix-turn-helix domain Mur_ligase_M PF08245.12 CBY37430.1 - 5.9e-09 36.2 0.0 1.6e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain zf-LSD1 PF06943.12 CBY37430.1 - 1.1 9.2 6.4 0.52 10.2 2.8 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Mur_ligase_M PF08245.12 CBY37431.1 - 1.3e-10 41.6 0.0 1.2e-05 25.4 0.0 2.8 2 1 0 2 2 2 2 Mur ligase middle domain DUF3630 PF12305.8 CBY37431.1 - 0.027 14.6 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) Mur_ligase_C PF02875.21 CBY37431.1 - 0.028 14.7 0.0 0.086 13.1 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain UBA_6 PF18039.1 CBY37431.1 - 0.033 14.1 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain PSI_PsaE PF02427.17 CBY37431.1 - 0.068 12.8 0.0 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Rbsn PF11464.8 CBY37431.1 - 0.072 12.8 4.6 2.1 8.2 0.5 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain S4 PF01479.25 CBY37431.1 - 0.076 12.8 0.0 22 4.9 0.0 2.6 2 0 0 2 2 2 0 S4 domain zf-LSD1 PF06943.12 CBY37431.1 - 0.31 10.9 11.1 0.65 9.9 2.8 2.9 3 0 0 3 3 3 0 LSD1 zinc finger Phospholip_A2_1 PF00068.19 CBY37432.1 - 1.2e-09 38.6 7.1 1.7e-09 38.1 7.1 1.2 1 0 0 1 1 1 1 Phospholipase A2 DUF4710 PF15828.5 CBY37432.1 - 0.059 13.5 0.7 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4710) Metal_resist PF13801.6 CBY37434.1 - 0.0075 16.5 5.0 0.0075 16.5 5.0 11.8 7 4 4 12 12 12 1 Heavy-metal resistance DUF641 PF04859.12 CBY37435.1 - 0.0032 17.8 6.0 0.0032 17.8 6.0 8.5 1 1 6 7 7 7 2 Plant protein of unknown function (DUF641) APG6_N PF17675.1 CBY37435.1 - 0.0033 18.0 30.2 0.0033 18.0 30.2 6.0 2 2 4 6 6 6 1 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 CBY37435.1 - 0.0053 17.3 12.3 0.0053 17.3 12.3 7.7 1 1 6 7 7 7 2 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CBY37435.1 - 0.012 15.7 19.4 0.012 15.7 19.4 6.0 1 1 7 8 8 8 0 TPR/MLP1/MLP2-like protein FliJ PF02050.16 CBY37435.1 - 0.015 15.6 17.1 0.015 15.6 17.1 6.4 1 1 5 7 7 7 0 Flagellar FliJ protein Spc7 PF08317.11 CBY37435.1 - 0.024 13.5 125.1 0.14 11.0 25.6 4.9 1 1 4 5 5 5 0 Spc7 kinetochore protein DUF3584 PF12128.8 CBY37435.1 - 0.13 9.7 105.6 0.58 7.6 63.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 CBY37436.1 - 0.0013 18.8 21.0 0.0013 18.8 21.0 4.6 2 2 3 5 5 5 2 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CBY37436.1 - 0.0033 17.1 5.8 0.0033 17.1 5.8 4.3 2 1 2 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease JIP_LZII PF16471.5 CBY37436.1 - 0.018 15.2 4.3 0.018 15.2 4.3 6.6 3 1 3 7 7 7 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 CBY37436.1 - 0.042 14.5 3.9 0.042 14.5 3.9 7.2 3 2 3 7 7 7 0 SlyX KELK PF15796.5 CBY37436.1 - 0.07 13.6 1.2 0.07 13.6 1.2 6.9 2 2 3 6 6 6 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Mce4_CUP1 PF11887.8 CBY37436.1 - 0.2 11.1 13.6 0.097 12.1 3.6 2.6 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative APG6_N PF17675.1 CBY37436.1 - 0.98 10.0 77.2 0.19 12.2 18.4 5.3 1 1 4 5 5 5 0 Apg6 coiled-coil region ATG16 PF08614.11 CBY37436.1 - 3.2 7.9 60.7 4.7 7.4 11.9 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HalX PF08663.10 CBY37436.1 - 9.5 6.6 29.2 0.38 11.1 3.6 5.7 3 3 2 5 5 5 0 HalX domain Actin PF00022.19 CBY37437.1 - 1.5e-109 366.3 0.0 1.7e-109 366.2 0.0 1.0 1 0 0 1 1 1 1 Actin FtsA PF14450.6 CBY37437.1 - 0.04 14.3 0.1 0.2 12.1 0.0 2.2 2 1 0 2 2 2 0 Cell division protein FtsA RNase_T PF00929.24 CBY37438.1 - 0.00044 20.8 0.1 0.0031 18.1 0.1 2.2 1 1 0 1 1 1 1 Exonuclease zf-MYND PF01753.18 CBY37439.1 - 6.2e-06 26.2 10.0 1.7e-05 24.8 10.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CBY37439.1 - 0.0053 17.0 6.9 0.055 13.8 3.0 2.7 1 1 1 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Tup_N PF08581.10 CBY37439.1 - 0.018 15.3 6.8 0.018 15.3 6.8 2.5 2 0 0 2 2 2 0 Tup N-terminal PKcGMP_CC PF16808.5 CBY37439.1 - 0.13 12.2 0.4 0.13 12.2 0.4 4.2 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ADIP PF11559.8 CBY37439.1 - 0.76 9.9 28.2 9.8 6.2 12.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Ferritin PF00210.24 CBY37439.1 - 0.76 9.7 8.4 0.53 10.2 6.3 1.8 1 1 0 1 1 1 0 Ferritin-like domain DUF1664 PF07889.12 CBY37439.1 - 3.9 7.5 9.5 3 7.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 CBY37439.1 - 7.6 5.3 11.2 8.9 5.1 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EF1G PF00647.19 CBY37440.1 - 7.1e-39 132.2 0.1 1.3e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBY37440.1 - 1.3e-09 38.1 0.9 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY37440.1 - 0.00019 21.4 0.1 0.00043 20.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBY37440.1 - 0.00047 20.3 0.0 0.0018 18.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY37441.1 - 3.9e-07 30.3 0.0 4.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FoP_duplication PF13865.6 CBY37441.1 - 0.75 10.4 10.3 1 9.9 10.3 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SKIP_SNW PF02731.15 CBY37442.1 - 1.1e-71 239.7 2.7 1.1e-71 239.7 2.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Plasmodium_Vir PF05795.11 CBY37442.1 - 4.4 6.6 6.3 1.3 8.4 2.0 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ALIX_LYPXL_bnd PF13949.6 CBY37443.1 - 2.9e-79 266.4 10.6 4e-79 266.0 10.6 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CagS PF16707.5 CBY37443.1 - 0.029 14.4 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Cir_Bir_Yir PF06022.11 CBY37443.1 - 0.047 13.2 4.0 0.02 14.4 1.8 1.5 2 0 0 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir Nmad5 PF18757.1 CBY37443.1 - 0.11 12.7 1.6 2.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Nucleotide modification associated domain 5 Xpo1 PF08389.12 CBY37443.1 - 0.16 12.1 1.3 0.4 10.7 0.6 1.9 1 1 1 2 2 2 0 Exportin 1-like protein YkyA PF10368.9 CBY37443.1 - 1.1 8.9 12.3 0.35 10.5 5.1 3.0 3 1 0 3 3 3 0 Putative cell-wall binding lipoprotein Trypsin PF00089.26 CBY37444.1 - 4.2e-28 98.7 0.7 6.4e-28 98.1 0.7 1.2 1 0 0 1 1 1 1 Trypsin Folate_rec PF03024.14 CBY37445.1 - 1.8e-07 31.2 20.4 6.2e-07 29.4 19.3 2.3 1 1 0 1 1 1 1 Folate receptor family Podoplanin PF05808.11 CBY37445.1 - 0.00022 21.3 2.9 0.00052 20.1 2.9 1.5 1 0 0 1 1 1 1 Podoplanin zf-RING_5 PF14634.6 CBY37446.1 - 0.0071 16.3 2.3 0.012 15.5 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF3450 PF11932.8 CBY37446.1 - 0.027 13.8 20.8 0.12 11.7 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-C3HC4_3 PF13920.6 CBY37446.1 - 0.32 10.9 2.1 0.85 9.5 2.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 CBY37446.1 - 0.39 10.8 16.5 0.61 10.2 16.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-RING_UBOX PF13445.6 CBY37446.1 - 0.4 10.8 3.5 0.72 9.9 3.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger SHE3 PF17078.5 CBY37446.1 - 0.64 9.7 17.6 0.96 9.1 17.6 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 CBY37446.1 - 1.3 9.1 21.3 4.2 7.5 7.7 3.7 1 1 3 4 4 4 0 bZIP transcription factor Exonuc_VII_L PF02601.15 CBY37446.1 - 1.8 8.1 11.2 2.6 7.5 11.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NES_C_h PF18208.1 CBY37446.1 - 2.9 8.2 14.9 9.6 6.5 10.4 2.8 1 1 2 3 3 3 0 Nicking enzyme C-terminal middle helical domain Med9 PF07544.13 CBY37446.1 - 2.9 8.0 17.9 0.17 12.0 4.2 3.1 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 CBY37446.1 - 3 7.0 9.6 0.86 8.8 0.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 CBY37446.1 - 8.7 6.8 21.8 2.1 8.8 1.8 2.4 1 1 0 2 2 2 0 Centromere protein H (CENP-H) zf-H2C2_5 PF13909.6 CBY37447.1 - 0.00018 21.2 4.8 0.00018 21.2 4.8 2.4 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY37447.1 - 0.011 16.1 5.7 0.011 16.1 5.7 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type CRM1_repeat_2 PF18784.1 CBY37447.1 - 0.077 12.7 0.7 0.22 11.2 0.7 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 CUE PF02845.16 CBY37448.1 - 1.1 9.0 2.9 3.5 7.4 0.1 2.9 3 0 0 3 3 3 0 CUE domain VWA PF00092.28 CBY37449.1 - 1.5e-15 57.9 0.0 1.8e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CBY37450.1 - 8.7e-16 57.9 25.3 1.7e-08 34.5 10.2 2.3 2 0 0 2 2 2 2 Thrombospondin type 1 domain FXa_inhibition PF14670.6 CBY37451.1 - 7.2e-12 45.4 35.7 3.1e-10 40.1 9.4 6.3 5 1 1 6 6 6 3 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY37451.1 - 5.1e-07 29.8 10.9 5.1e-07 29.8 10.9 6.7 7 1 0 7 7 7 2 Calcium-binding EGF domain VWA PF00092.28 CBY37451.1 - 9e-07 29.3 0.0 1.3e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain cEGF PF12662.7 CBY37451.1 - 0.0001 22.1 1.4 0.0001 22.1 1.4 6.4 6 0 0 6 6 6 3 Complement Clr-like EGF-like VWA_2 PF13519.6 CBY37451.1 - 0.067 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain FXa_inhibition PF14670.6 CBY37452.1 - 7.5e-24 83.7 66.0 5.7e-10 39.3 8.0 5.7 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site VWA PF00092.28 CBY37452.1 - 8.8e-24 84.7 0.0 1.1e-23 84.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY37452.1 - 3.7e-15 56.5 0.1 5.3e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain EGF_CA PF07645.15 CBY37452.1 - 1.1e-11 44.7 58.9 2.3e-05 24.5 7.3 4.7 5 0 0 5 5 5 4 Calcium-binding EGF domain cEGF PF12662.7 CBY37452.1 - 7.2e-11 41.8 27.5 5.2e-05 23.1 1.0 6.5 7 0 0 7 7 7 3 Complement Clr-like EGF-like EGF PF00008.27 CBY37452.1 - 1.9e-05 24.9 60.1 0.01 16.1 5.7 5.7 5 1 0 5 5 5 4 EGF-like domain Sec23_trunk PF04811.15 CBY37452.1 - 0.001 18.7 0.1 0.0015 18.2 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain EGF_3 PF12947.7 CBY37452.1 - 0.027 14.7 6.1 0.027 14.7 6.1 5.0 5 0 0 5 5 5 0 EGF domain hEGF PF12661.7 CBY37452.1 - 0.075 13.7 49.6 0.12 13.0 6.5 6.0 5 1 0 5 5 5 0 Human growth factor-like EGF Toprim_Crpt PF13342.6 CBY37454.1 - 0.018 15.0 1.2 0.077 13.0 0.3 2.1 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase HSF_DNA-bind PF00447.17 CBY37455.1 - 8.8e-13 48.7 1.1 1.8e-12 47.7 1.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5344 PF17279.2 CBY37455.1 - 0.34 11.5 3.5 5 7.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Striatin PF08232.12 CBY37455.1 - 9.4 6.8 11.3 2.9 8.5 3.6 2.3 1 1 1 2 2 2 0 Striatin family Prok-E2_E PF14462.6 CBY37456.1 - 0.06 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E POLO_box PF00659.18 CBY37456.1 - 0.068 13.4 1.1 2.3 8.5 0.0 2.7 1 1 1 2 2 2 0 POLO box duplicated region Lipase_3 PF01764.25 CBY37458.1 - 1.7e-19 70.1 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY37458.1 - 1.2e-05 26.1 0.0 1.3e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CBY37458.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY37458.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 CBY37458.1 - 0.0024 17.5 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CBY37458.1 - 0.0028 17.4 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY37458.1 - 0.004 17.3 0.0 0.0099 16.0 0.0 1.6 1 1 1 2 2 2 1 Thioesterase domain Lipase_2 PF01674.18 CBY37458.1 - 0.0055 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Hydrolase_4 PF12146.8 CBY37458.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY37458.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CBY37458.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-H2C2_2 PF13465.6 CBY37460.1 - 3.1e-16 59.0 17.8 7e-10 38.9 0.5 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CBY37460.1 - 8.4e-14 51.2 21.7 3.4e-05 24.0 0.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37460.1 - 1.9e-09 37.5 18.3 0.0035 18.0 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY37460.1 - 0.0026 17.7 12.7 0.57 10.2 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY37460.1 - 0.0063 16.8 7.4 0.53 10.6 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY37460.1 - 0.014 15.8 8.2 0.59 10.6 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CBY37460.1 - 0.031 14.2 7.0 0.15 12.0 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CBY37460.1 - 0.044 14.1 3.4 0.079 13.3 3.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-Di19 PF05605.12 CBY37460.1 - 0.54 10.6 9.0 0.78 10.1 1.2 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BK_channel_a PF03493.18 CBY37462.1 - 1.3e-32 111.9 0.0 3e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 CBY37462.1 - 0.001 19.3 0.0 0.022 15.0 0.1 2.4 2 0 0 2 2 2 1 TrkA-N domain Guanylate_cyc PF00211.20 CBY37466.1 - 1.7e-34 119.0 0.0 1.9e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans_2 PF07885.16 CBY37467.1 - 1.2e-10 41.2 0.4 2.1e-10 40.4 0.4 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY37467.1 - 1e-07 31.5 0.7 1.6e-07 30.8 0.7 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 CBY37467.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBY37467.1 - 0.03 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF5432 PF17497.2 CBY37467.1 - 0.077 13.1 0.6 5.2 7.3 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5432) PRR20 PF15708.5 CBY37467.1 - 0.29 11.0 0.0 0.44 10.4 0.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 COP23 PF14218.6 CBY37469.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Filament PF00038.21 CBY37470.1 - 0.00028 20.6 12.5 0.0068 16.0 5.0 2.2 2 0 0 2 2 2 2 Intermediate filament protein Golgin_A5 PF09787.9 CBY37470.1 - 0.0015 18.1 14.7 0.0028 17.2 7.4 2.2 2 0 0 2 2 2 2 Golgin subfamily A member 5 ICL PF00463.21 CBY37470.1 - 0.052 12.0 0.1 0.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Isocitrate lyase family PRKG1_interact PF15898.5 CBY37470.1 - 0.12 13.3 20.4 8.1 7.4 0.1 4.0 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBY37470.1 - 0.25 11.5 8.6 0.24 11.6 0.4 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KIAA1430 PF13879.6 CBY37470.1 - 0.56 11.0 11.3 4.5 8.1 1.2 2.8 2 1 1 3 3 3 0 KIAA1430 homologue PKcGMP_CC PF16808.5 CBY37470.1 - 0.82 9.6 9.3 2.5 8.0 0.7 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 CBY37470.1 - 0.83 8.5 19.2 0.1 11.5 3.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CBY37470.1 - 2.8 7.7 14.8 4 7.2 6.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6_N PF17675.1 CBY37470.1 - 3.1 8.3 25.9 1.7 9.2 18.4 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_23 PF13476.6 CBY37470.1 - 3.9 7.9 14.8 0.11 13.0 0.4 2.5 3 0 0 3 3 2 0 AAA domain UPF0242 PF06785.11 CBY37470.1 - 4.2 7.4 13.7 9.3 6.3 1.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Enkurin PF13864.6 CBY37470.1 - 4.5 7.8 16.7 5.7 7.4 3.4 3.3 3 0 0 3 3 3 0 Calmodulin-binding TPR_MLP1_2 PF07926.12 CBY37470.1 - 7.3 6.7 27.9 0.25 11.4 7.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 CBY37471.1 - 0.0093 16.0 0.8 0.036 14.1 0.2 1.9 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 DUF818 PF05677.12 CBY37472.1 - 0.00015 20.9 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 CBY37472.1 - 0.0089 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY37472.1 - 0.019 14.6 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY37472.1 - 0.14 12.8 0.0 0.21 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF5526 PF17664.1 CBY37473.1 - 9.6e-13 48.0 9.5 1.2e-12 47.8 9.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5526) cEGF PF12662.7 CBY37474.1 - 0.00032 20.6 4.8 0.00033 20.5 1.7 2.8 2 0 0 2 2 2 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY37474.1 - 0.012 15.8 3.2 0.012 15.8 3.2 3.8 3 1 0 3 3 3 0 Coagulation Factor Xa inhibitory site TSP_1 PF00090.19 CBY37475.1 - 9.8e-06 25.7 16.7 2e-05 24.7 16.7 1.6 1 0 0 1 1 1 1 Thrombospondin type 1 domain FSA_C PF10479.9 CBY37475.1 - 3.1 5.8 23.6 4.2 5.4 23.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RNase_H PF00075.24 CBY37476.1 - 2.3e-21 76.5 0.0 3.7e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 CBY37476.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like S-AdoMet_synt_C PF02773.16 CBY37477.1 - 3.4e-68 227.9 0.1 6.2e-68 227.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBY37477.1 - 7e-43 145.7 0.0 1.4e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBY37477.1 - 5.2e-42 142.5 0.7 2.3e-41 140.5 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CBY37477.1 - 0.051 12.4 0.5 0.17 10.6 0.2 1.8 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Rhodanese PF00581.20 CBY37479.1 - 2.4e-07 31.2 0.0 2.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AA_permease_2 PF13520.6 CBY37480.1 - 1e-56 192.6 47.4 1.3e-56 192.2 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY37480.1 - 9.1e-35 120.2 39.5 1.3e-34 119.6 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease SET PF00856.28 CBY37482.1 - 6.3e-06 26.7 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 SET domain rve PF00665.26 CBY37486.1 - 1.1e-13 51.5 0.0 1.5e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain FCH PF00611.23 CBY37487.1 - 0.051 13.9 0.3 0.14 12.5 0.3 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain SRP-alpha_N PF04086.13 CBY37487.1 - 0.19 11.6 12.4 0.35 10.7 12.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Xan_ur_permease PF00860.20 CBY37488.1 - 1.3e-54 185.4 3.0 1.3e-54 185.4 3.0 1.4 2 0 0 2 2 2 1 Permease family Trefoil PF00088.18 CBY37489.1 - 4.3e-11 42.5 5.4 7.2e-11 41.8 5.4 1.4 1 0 0 1 1 1 1 Trefoil (P-type) domain EutC PF05985.11 CBY37490.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) TauD PF02668.16 CBY37492.1 - 2.9e-13 50.2 0.0 6.7e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GNT-I PF03071.15 CBY37494.1 - 3.2e-49 167.9 1.2 5.7e-48 163.7 1.2 2.5 1 1 0 1 1 1 1 GNT-I family fn3 PF00041.21 CBY37495.1 - 0.0073 16.6 0.2 0.25 11.7 0.0 3.2 2 1 1 3 3 3 1 Fibronectin type III domain zf-TAZ PF02135.16 CBY37496.1 - 4.3e-09 36.7 16.8 5.8e-09 36.3 16.8 1.2 1 0 0 1 1 1 1 TAZ zinc finger Pkinase PF00069.25 CBY37497.1 - 1.2e-59 201.9 0.0 2.3e-59 200.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 CBY37497.1 - 1.3e-29 102.1 0.0 5.6e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY37497.1 - 2.7e-27 95.7 0.0 4.7e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY37497.1 - 7.5e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY37497.1 - 0.00014 21.8 0.1 0.00023 21.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY37497.1 - 0.00044 19.1 0.1 0.00082 18.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase TSC22 PF01166.18 CBY37497.1 - 0.0012 19.1 0.6 0.0031 17.8 0.6 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Choline_kinase PF01633.20 CBY37497.1 - 0.015 14.8 0.1 0.054 13.1 0.1 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase PspA_IM30 PF04012.12 CBY37497.1 - 0.026 14.1 0.9 0.046 13.3 0.9 1.3 1 0 0 1 1 1 0 PspA/IM30 family YabA PF06156.13 CBY37497.1 - 0.048 14.3 0.6 0.16 12.6 0.3 2.0 2 0 0 2 2 2 0 Initiation control protein YabA Cnn_1N PF07989.11 CBY37497.1 - 0.072 13.3 2.3 0.2 11.9 2.3 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Kdo PF06293.14 CBY37497.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tiam_CC_Ex PF18385.1 CBY37497.1 - 0.18 12.2 0.5 0.45 11.0 0.5 1.6 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain bZIP_1 PF00170.21 CBY37497.1 - 0.23 11.6 2.1 0.57 10.3 2.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF3783 PF12646.7 CBY37497.1 - 0.25 11.3 2.4 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) Pro_racemase PF05544.11 CBY37500.1 - 0.097 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Proline racemase Connexin PF00029.19 CBY37501.1 - 1.3e-54 185.4 3.4 1.5e-54 185.3 3.4 1.0 1 0 0 1 1 1 1 Connexin adh_short PF00106.25 CBY37502.1 - 5.3e-17 61.9 0.0 7.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY37502.1 - 4.1e-10 39.6 0.0 5.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY37502.1 - 0.00025 21.0 0.0 0.00042 20.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY37502.1 - 0.049 13.1 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Trypsin PF00089.26 CBY37505.1 - 1.9e-06 27.8 3.3 9.2e-06 25.6 3.3 1.9 1 1 0 1 1 1 1 Trypsin GST_N_3 PF13417.6 CBY37506.1 - 6.7e-14 52.1 0.0 7.2e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY37506.1 - 2e-12 47.3 0.0 2.3e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY37506.1 - 1.2e-09 38.4 0.0 1.4e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PhoLip_ATPase_C PF16212.5 CBY37508.1 - 1.2e-63 215.2 25.0 1.2e-63 215.2 25.0 3.0 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY37508.1 - 2.1e-22 78.6 3.9 2.1e-22 78.6 3.9 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CBY37508.1 - 1.7e-10 40.8 0.0 4.2e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBY37508.1 - 1.8e-09 37.4 0.4 5.7e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY37508.1 - 1.3e-08 35.4 1.9 1.3e-05 25.6 1.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY37508.1 - 0.012 15.4 0.4 0.052 13.3 0.4 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TcdA_TcdB_pore PF12920.7 CBY37508.1 - 0.072 11.3 0.1 0.12 10.7 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain 7tm_1 PF00001.21 CBY37509.1 - 3.3e-32 111.9 11.2 4e-32 111.6 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY37509.1 - 1.2e-13 51.3 14.8 1.6e-13 50.9 14.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx 7TM_GPCR_Srsx PF10320.9 CBY37509.1 - 2.6e-06 27.0 14.1 4.3e-06 26.3 14.1 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7TM_GPCR_Srv PF10323.9 CBY37509.1 - 7.6e-05 22.2 14.6 0.00011 21.6 14.6 1.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv 7tm_4 PF13853.6 CBY37509.1 - 0.0084 15.9 3.0 0.013 15.3 3.0 1.2 1 0 0 1 1 1 1 Olfactory receptor tRNA_NucTran2_2 PF13735.6 CBY37510.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.0 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Phospholip_A2_1 PF00068.19 CBY37511.1 - 8.6e-12 45.5 0.5 8.6e-12 45.5 0.5 1.6 2 0 0 2 2 2 1 Phospholipase A2 FA_hydroxylase PF04116.13 CBY37512.1 - 1.6e-14 54.4 13.3 2.2e-14 54.0 13.3 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Tropomyosin PF00261.20 CBY37513.1 - 1.3e-26 93.4 28.6 1.6e-26 93.2 28.6 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CBY37513.1 - 3.3e-12 46.7 30.1 1.5e-11 44.7 30.1 1.9 1 1 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.8 CBY37513.1 - 9.3e-05 22.4 28.2 0.0018 18.3 16.8 2.4 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding T3SSipB PF16535.5 CBY37513.1 - 0.00056 20.4 14.4 0.00084 19.8 13.5 1.7 1 1 0 1 1 1 1 Type III cell invasion protein SipB APG6_N PF17675.1 CBY37513.1 - 0.0015 19.0 30.5 0.086 13.4 17.4 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region Lebercilin PF15619.6 CBY37513.1 - 0.0027 17.4 22.3 0.0035 17.0 22.3 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 CBY37513.1 - 0.0037 17.3 5.9 0.0037 17.3 5.9 3.1 1 1 2 3 3 3 1 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 CBY37513.1 - 0.0057 16.7 27.9 0.069 13.2 5.1 2.4 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain Nsp1_C PF05064.13 CBY37513.1 - 0.0072 16.1 6.7 0.0072 16.1 6.7 2.2 1 1 0 2 2 2 1 Nsp1-like C-terminal region bZIP_1 PF00170.21 CBY37513.1 - 0.009 16.1 4.7 0.009 16.1 4.7 2.8 2 1 0 3 3 2 1 bZIP transcription factor GAS PF13851.6 CBY37513.1 - 0.022 14.1 24.0 0.16 11.3 24.0 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 CBY37513.1 - 0.026 14.6 17.2 0.037 14.1 17.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 CBY37513.1 - 0.026 14.9 6.5 0.026 14.9 6.5 3.1 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 CBY37513.1 - 0.032 13.1 27.3 0.49 9.2 16.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBY37513.1 - 0.035 14.5 14.7 0.11 12.9 14.8 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) RasGAP_C PF03836.15 CBY37513.1 - 0.046 13.9 9.7 0.092 12.9 9.8 1.7 1 1 0 1 1 1 0 RasGAP C-terminus FPP PF05911.11 CBY37513.1 - 0.051 11.8 21.5 0.062 11.5 21.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Baculo_PEP_C PF04513.12 CBY37513.1 - 0.057 13.5 6.1 2.4 8.2 4.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 CBY37513.1 - 0.058 13.8 21.5 0.18 12.2 21.4 1.7 1 1 0 1 1 1 0 Fez1 CCDC144C PF14915.6 CBY37513.1 - 0.062 12.4 22.2 0.092 11.8 19.7 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF2785 PF10978.8 CBY37513.1 - 0.069 12.9 3.8 1.3 8.7 1.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2785) Cast PF10174.9 CBY37513.1 - 0.085 11.1 21.2 0.14 10.3 21.2 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Laminin_II PF06009.12 CBY37513.1 - 0.099 12.7 16.1 2.4 8.2 8.1 2.9 1 1 2 3 3 3 0 Laminin Domain II DUF4201 PF13870.6 CBY37513.1 - 0.16 11.7 23.9 0.42 10.3 14.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ERM PF00769.19 CBY37513.1 - 0.16 11.8 26.5 2.2 8.0 22.0 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Leu_zip PF15294.6 CBY37513.1 - 0.18 11.3 21.9 0.31 10.5 21.9 1.4 1 1 0 1 1 1 0 Leucine zipper Filament PF00038.21 CBY37513.1 - 0.18 11.4 21.5 0.6 9.6 8.5 2.0 1 1 1 2 2 2 0 Intermediate filament protein Laminin_I PF06008.14 CBY37513.1 - 0.2 11.3 22.9 0.37 10.4 4.0 2.0 1 1 1 2 2 2 0 Laminin Domain I KxDL PF10241.9 CBY37513.1 - 0.2 11.9 13.4 3.3 8.1 0.7 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF724 PF05266.14 CBY37513.1 - 0.21 11.4 20.2 0.17 11.7 15.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2009 PF09418.10 CBY37513.1 - 0.23 10.5 4.9 0.25 10.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF4472 PF14739.6 CBY37513.1 - 0.24 12.2 18.4 0.91 10.3 6.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Tweety PF04906.13 CBY37513.1 - 0.24 10.0 3.3 1.5 7.4 0.0 2.0 1 1 1 2 2 2 0 Tweety DUF948 PF06103.11 CBY37513.1 - 0.29 11.4 9.2 0.86 9.9 2.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HOOK PF05622.12 CBY37513.1 - 0.31 9.2 24.5 7.6 4.5 24.4 1.9 1 1 0 1 1 1 0 HOOK protein ABC_tran_CTD PF16326.5 CBY37513.1 - 0.33 11.2 27.3 2.3 8.5 2.3 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain EzrA PF06160.12 CBY37513.1 - 0.39 8.9 23.3 0.24 9.5 19.7 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMPIT PF07851.13 CBY37513.1 - 0.41 9.9 12.3 0.45 9.7 11.4 1.6 1 1 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 CBY37513.1 - 0.43 10.6 27.8 0.33 11.0 15.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YscO PF07321.12 CBY37513.1 - 0.48 10.4 20.7 0.18 11.7 9.8 2.5 1 1 1 2 2 2 0 Type III secretion protein YscO ADIP PF11559.8 CBY37513.1 - 0.52 10.4 22.1 0.45 10.6 12.2 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 CBY37513.1 - 0.75 9.8 15.5 0.64 10.1 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY37513.1 - 0.78 10.2 17.6 2 8.9 1.9 4.1 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 CBY37513.1 - 0.78 10.2 18.0 0.84 10.1 6.7 2.8 1 1 1 2 2 2 0 Snapin/Pallidin Prominin PF05478.11 CBY37513.1 - 0.95 7.3 8.8 1 7.3 8.8 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 CBY37513.1 - 0.98 9.5 25.2 0.074 13.1 14.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5340 PF17275.2 CBY37513.1 - 1 9.6 6.1 0.23 11.6 1.5 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5340) Cep57_CLD PF14073.6 CBY37513.1 - 1 9.3 23.5 4 7.4 10.2 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF4407 PF14362.6 CBY37513.1 - 1 8.6 14.2 1.4 8.2 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CBY37513.1 - 1.2 8.4 20.9 0.31 10.3 11.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 CBY37513.1 - 1.2 7.9 10.5 1.4 7.8 10.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF745 PF05335.13 CBY37513.1 - 1.4 8.6 13.4 1.3 8.7 11.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) HAUS-augmin3 PF14932.6 CBY37513.1 - 1.5 8.4 21.1 1.1 8.7 9.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Fmp27_WPPW PF10359.9 CBY37513.1 - 2.3 7.0 18.9 4 6.2 18.9 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.20 CBY37513.1 - 3.4 7.7 28.3 3 7.8 4.4 4.4 1 1 3 4 4 4 0 Prefoldin subunit HMMR_N PF15905.5 CBY37513.1 - 3.7 6.9 25.3 0.71 9.3 14.4 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 CBY37513.1 - 3.8 7.7 26.9 4.9 7.3 12.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CHIP_TPR_N PF18391.1 CBY37513.1 - 4 8.3 20.7 5.5 7.8 16.0 2.7 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DUF2730 PF10805.8 CBY37513.1 - 4.5 7.4 9.9 1.4 9.0 2.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) COG2 PF06148.11 CBY37513.1 - 4.6 7.3 13.9 7.2 6.7 1.0 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1635 PF07795.11 CBY37513.1 - 5.3 6.8 17.3 7.4 6.4 16.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) DLP_helical PF18709.1 CBY37513.1 - 5.7 6.0 15.2 4.1 6.5 1.5 2.2 1 1 0 2 2 2 0 Dynamin-like helical domain TSNAXIP1_N PF15739.5 CBY37513.1 - 7 7.1 20.2 1.1 9.7 8.6 2.9 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus MCU PF04678.13 CBY37513.1 - 7.5 6.6 13.1 3.4 7.7 0.6 2.3 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Uds1 PF15456.6 CBY37513.1 - 7.9 6.7 17.9 2.5 8.3 14.2 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Tropomyosin PF00261.20 CBY37514.1 - 0.00091 18.7 5.6 0.0024 17.3 5.6 1.6 1 1 0 1 1 1 1 Tropomyosin SF-assemblin PF06705.11 CBY37514.1 - 0.0031 16.9 3.5 0.0031 16.9 3.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin HIP1_clath_bdg PF16515.5 CBY37514.1 - 0.0036 17.9 2.3 0.0039 17.8 2.3 1.1 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 XRCC4 PF06632.12 CBY37514.1 - 0.0045 15.9 2.4 0.0051 15.7 2.4 1.0 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 APG6_N PF17675.1 CBY37514.1 - 0.015 15.8 4.6 0.017 15.7 4.6 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 CBY37514.1 - 0.022 14.8 2.5 0.023 14.8 1.4 1.6 1 1 1 2 2 2 0 bZIP transcription factor Mis14 PF08641.12 CBY37514.1 - 0.058 13.7 2.0 0.064 13.6 2.0 1.0 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DUF1664 PF07889.12 CBY37514.1 - 0.062 13.3 1.4 0.066 13.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ZapB PF06005.12 CBY37514.1 - 0.07 13.6 5.1 0.094 13.2 5.1 1.2 1 0 0 1 1 1 0 Cell division protein ZapB DUF4164 PF13747.6 CBY37514.1 - 0.093 13.0 4.6 0.14 12.4 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3496 PF12001.8 CBY37514.1 - 0.12 12.7 2.3 0.29 11.5 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) DivIC PF04977.15 CBY37514.1 - 0.16 11.8 3.5 0.26 11.1 3.5 1.5 1 1 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 CBY37514.1 - 0.16 12.2 2.9 0.12 12.6 1.5 1.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YojJ PF10372.9 CBY37514.1 - 0.18 11.9 1.5 6.2 7.0 0.1 2.0 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF3618 PF12277.8 CBY37514.1 - 0.56 10.5 5.9 1.8 8.9 4.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3618) HSP20 PF00011.21 CBY37516.1 - 0.0099 16.0 0.2 0.72 10.0 0.0 2.8 2 1 1 3 3 3 2 Hsp20/alpha crystallin family RGS12_usC PF16612.5 CBY37516.1 - 0.025 15.0 0.3 0.071 13.5 0.1 1.7 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 GIDE PF12483.8 CBY37516.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase HpaP PF09483.10 CBY37516.1 - 0.12 12.7 0.1 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Type III secretion protein (HpaP) DNA_ligase_A_M PF01068.21 CBY37517.1 - 6.2e-48 163.1 0.2 3.1e-27 95.6 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CBY37517.1 - 3.7e-41 141.3 0.0 1.4e-40 139.4 0.0 2.1 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CBY37517.1 - 3.3e-23 82.1 0.7 2.4e-22 79.4 0.0 3.0 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region FG-GAP_2 PF14312.6 CBY37517.1 - 0.19 12.0 0.6 0.42 10.9 0.6 1.5 1 0 0 1 1 1 0 FG-GAP repeat WD40 PF00400.32 CBY37518.1 - 9.7e-09 35.7 3.9 0.019 15.8 0.6 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37518.1 - 0.00043 20.5 0.1 1.1 9.6 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Integrin_alpha2 PF08441.12 CBY37520.1 - 2.1e-14 53.3 0.7 9.8e-14 51.1 0.0 2.2 1 1 0 2 2 2 1 Integrin alpha FG-GAP PF01839.23 CBY37520.1 - 1.8e-06 27.9 1.9 1.8e-06 27.9 1.9 3.3 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 CBY37520.1 - 2.7e-05 24.7 3.8 0.00029 21.4 0.5 2.2 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 CBY37520.1 - 0.0022 18.2 6.9 0.26 11.6 0.4 4.9 5 0 0 5 5 5 1 FG-GAP repeat MT PF12777.7 CBY37521.1 - 1.4e-10 40.8 0.3 8.5e-10 38.2 0.2 2.2 1 1 1 2 2 2 1 Microtubule-binding stalk of dynein motor IL2 PF00715.17 CBY37521.1 - 0.018 15.0 4.0 0.11 12.5 1.9 2.9 2 0 0 2 2 2 0 Interleukin 2 DUF4600 PF15372.6 CBY37521.1 - 0.096 13.1 9.6 0.038 14.4 4.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF5600 PF18150.1 CBY37521.1 - 0.15 12.6 2.0 0.46 11.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) DUF892 PF05974.12 CBY37521.1 - 0.27 11.2 2.5 0.51 10.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) BLOC1_2 PF10046.9 CBY37521.1 - 6.3 7.2 12.0 5.2 7.5 0.7 4.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynein_AAA_lid PF17852.1 CBY37522.1 - 0.054 13.6 0.6 0.35 10.9 0.0 2.9 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain DUF948 PF06103.11 CBY37522.1 - 0.16 12.2 2.1 1.1 9.5 0.1 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 CBY37522.1 - 0.24 12.1 4.7 0.42 11.3 1.5 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Baculo_PEP_C PF04513.12 CBY37522.1 - 0.6 10.1 5.1 3.8 7.6 0.4 3.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0184 PF03670.13 CBY37522.1 - 6.1 7.3 11.9 4.6 7.7 2.8 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) MH2 PF03166.14 CBY37523.1 - 2.9e-37 128.7 0.7 2.9e-37 128.7 0.7 1.4 2 0 0 2 2 2 1 MH2 domain Troponin PF00992.20 CBY37524.1 - 3e-23 82.6 41.7 1.4e-22 80.5 37.9 2.0 1 1 1 2 2 2 2 Troponin DUF262 PF03235.14 CBY37524.1 - 3.5 7.8 11.8 4.8 7.3 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 UPF0054 PF02130.17 CBY37525.1 - 0.057 13.2 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Trypsin PF00089.26 CBY37526.1 - 2.6e-65 220.3 0.1 5.8e-65 219.2 0.1 1.6 1 1 0 1 1 1 1 Trypsin CUB PF00431.20 CBY37526.1 - 8.8e-06 26.0 0.2 3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 CUB domain DUF1986 PF09342.11 CBY37526.1 - 0.001 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Tmem26 PF09772.9 CBY37527.1 - 1.2e-42 146.3 5.7 3.8e-42 144.6 5.7 1.7 1 1 0 1 1 1 1 Transmembrane protein 26 CECR6_TMEM121 PF14997.6 CBY37527.1 - 0.0051 16.7 2.4 0.0051 16.7 2.4 3.2 2 1 1 3 3 3 1 CECR6/TMEM121 family Astacin PF01400.24 CBY37528.1 - 2e-12 47.2 0.0 6.3e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY37528.1 - 3.5e-07 30.3 4.2 3.5e-07 30.3 4.2 4.1 4 0 0 4 4 4 1 Calcium-binding EGF domain Gly_transf_sug PF04488.15 CBY37529.1 - 1.2e-09 38.6 0.0 2.8e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CBY37529.1 - 0.0058 16.1 0.6 0.0058 16.1 0.6 1.8 2 1 0 2 2 2 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 CBY37529.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain cNMP_binding PF00027.29 CBY37530.1 - 7.9e-08 32.3 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2894 PF11445.8 CBY37530.1 - 0.022 15.2 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cupin_3 PF05899.12 CBY37530.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 CBY37530.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain CLZ PF16526.5 CBY37531.1 - 0.0081 16.5 0.7 0.013 15.8 0.7 1.3 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels betaPIX_CC PF16523.5 CBY37531.1 - 0.019 14.8 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 betaPIX coiled coil Trypsin PF00089.26 CBY37532.1 - 4.7e-38 131.2 0.0 5.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY37532.1 - 0.0016 19.3 0.0 0.0031 18.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY37532.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Laminin_N PF00055.17 CBY37533.1 - 1.3e-76 257.3 0.6 7.5e-76 254.8 0.6 2.5 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY37533.1 - 4.1e-73 241.4 221.1 2e-11 43.8 12.4 11.4 11 0 0 11 11 11 10 Laminin EGF domain Laminin_B PF00052.18 CBY37533.1 - 2.6e-14 53.3 0.0 5.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF745 PF05335.13 CBY37533.1 - 0.00049 19.9 3.4 0.00049 19.9 3.4 5.4 2 2 5 7 7 7 1 Protein of unknown function (DUF745) DUF3921 PF13060.6 CBY37533.1 - 0.22 11.6 0.8 4.4 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) SmAKAP PF15127.6 CBY37533.1 - 1.9 9.8 0.0 1.9 9.8 0.0 3.7 3 0 0 3 3 3 0 Small membrane A-kinase anchor protein DASH_Dam1 PF08653.10 CBY37533.1 - 1.9 8.3 7.4 18 5.2 0.1 4.2 3 1 1 4 4 4 0 DASH complex subunit Dam1 ApoO PF09769.9 CBY37533.1 - 4.2 7.3 8.6 8.3 6.4 0.1 3.9 3 1 0 3 3 3 0 Apolipoprotein O LRR_4 PF12799.7 CBY37534.1 - 1.5e-19 69.7 29.8 1.8e-06 28.1 2.2 6.4 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY37534.1 - 1.3e-15 57.4 13.5 1.1e-11 44.6 0.3 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBY37534.1 - 9.7e-15 54.1 27.7 9.2e-07 28.5 4.1 5.1 4 1 1 5 5 5 4 Leucine rich repeat Terminase_2 PF03592.16 CBY37534.1 - 0.02 15.3 0.1 0.049 14.1 0.1 1.6 1 0 0 1 1 1 0 Terminase small subunit FRP PF18032.1 CBY37534.1 - 0.11 13.2 2.1 0.47 11.1 0.0 2.9 2 1 1 3 3 3 0 Photoprotection regulator fluorescence recovery protein LRR_6 PF13516.6 CBY37534.1 - 1.3 9.2 0.0 1.3 9.2 0.0 7.7 8 1 1 9 9 9 0 Leucine Rich repeat Kelch_1 PF01344.25 CBY37536.1 - 0.00018 21.0 0.8 2.1 8.0 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY37536.1 - 0.0026 17.7 2.9 2 8.5 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY37536.1 - 0.0042 17.3 5.0 9 6.7 0.0 4.8 4 1 1 5 5 5 2 Kelch motif Pox_A14 PF05767.12 CBY37538.1 - 0.052 13.7 0.3 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 zf-RING_2 PF13639.6 CBY37539.1 - 3.8e-09 36.7 5.9 3.8e-09 36.7 5.9 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY37539.1 - 1.6e-08 34.3 5.2 1.6e-08 34.3 5.2 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY37539.1 - 3.6e-07 30.0 7.5 3.6e-07 30.0 7.5 3.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY37539.1 - 1.1e-06 28.5 3.3 1.1e-06 28.5 3.3 3.1 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY37539.1 - 7.6e-06 25.7 6.9 7.6e-06 25.7 6.9 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY37539.1 - 9.7e-06 25.8 4.7 9.7e-06 25.8 4.7 3.3 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBY37539.1 - 1.8e-05 24.5 4.8 1.8e-05 24.5 4.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY37539.1 - 0.0013 18.8 3.0 0.0013 18.8 3.0 2.9 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY37539.1 - 0.0037 17.1 4.9 0.0037 17.1 4.9 3.2 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY37539.1 - 0.011 15.5 13.0 0.14 12.0 5.0 3.5 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain GyrI-like PF06445.15 CBY37539.1 - 0.062 13.6 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 GyrI-like small molecule binding domain MRP-L47 PF06984.13 CBY37539.1 - 0.09 12.9 7.1 0.17 12.0 1.3 2.9 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) zf_CopZ PF18423.1 CBY37539.1 - 0.23 11.5 6.4 2.1 8.4 0.0 3.5 3 0 0 3 3 3 0 Zinc binding domain CagY_M PF07337.11 CBY37539.1 - 3.4 7.4 8.9 1.6 8.4 0.1 3.8 3 0 0 3 3 3 0 DC-EC Repeat zf-ANAPC11 PF12861.7 CBY37539.1 - 8.7 6.5 10.6 0.63 10.1 1.5 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sulfotransfer_1 PF00685.27 CBY37540.1 - 1e-16 61.2 0.9 2.4e-16 60.0 0.9 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY37540.1 - 1.5e-09 38.5 0.1 1.2e-08 35.6 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase family SelB-wing_1 PF09105.10 CBY37542.1 - 0.069 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Tetraspanin PF00335.20 CBY37543.1 - 1.3e-08 34.9 0.4 1.6e-08 34.6 0.4 1.0 1 0 0 1 1 1 1 Tetraspanin family PLAT PF01477.23 CBY37544.1 - 3.5e-61 204.9 25.2 4.8e-20 72.3 0.2 5.7 6 0 0 6 6 6 5 PLAT/LH2 domain ATS3 PF06232.11 CBY37544.1 - 1.9e-12 47.2 1.1 0.11 12.4 0.0 5.8 3 2 2 5 5 5 4 Embryo-specific protein 3, (ATS3) PLAT PF01477.23 CBY37545.1 - 4.8e-21 75.5 2.3 1.4e-09 38.6 0.3 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain TRAP-gamma PF07074.12 CBY37546.1 - 2.7e-65 219.1 1.3 3.1e-65 218.9 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.6 CBY37546.1 - 0.024 14.8 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like LrgB PF04172.16 CBY37546.1 - 0.12 11.9 2.4 0.079 12.5 0.3 1.7 2 0 0 2 2 2 0 LrgB-like family 7tm_1 PF00001.21 CBY37547.1 - 4e-09 36.2 1.8 4.3e-09 36.1 0.7 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) CPBP PF02517.16 CBY37547.1 - 0.4 11.1 3.8 8.9 6.8 0.1 2.1 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease Podoplanin PF05808.11 CBY37547.1 - 5.6 7.0 6.1 9.1 6.4 6.1 1.2 1 0 0 1 1 1 0 Podoplanin LRR_8 PF13855.6 CBY37548.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeat Actin PF00022.19 CBY37550.1 - 7.5e-115 383.8 0.0 5.9e-114 380.8 0.0 1.8 1 1 0 1 1 1 1 Actin Trypsin PF00089.26 CBY37551.1 - 1.8e-09 37.8 1.2 8.3e-09 35.6 1.2 2.1 1 1 0 1 1 1 1 Trypsin PLAT PF01477.23 CBY37552.1 - 1.8e-61 205.8 25.4 4.8e-20 72.3 0.2 5.7 6 0 0 6 6 6 5 PLAT/LH2 domain ATS3 PF06232.11 CBY37552.1 - 1.8e-12 47.3 1.0 0.11 12.5 0.0 5.8 3 2 2 5 5 5 4 Embryo-specific protein 3, (ATS3) PLAT PF01477.23 CBY37553.1 - 4.8e-21 75.5 2.3 1.4e-09 38.6 0.3 2.1 2 0 0 2 2 2 2 PLAT/LH2 domain TRAP-gamma PF07074.12 CBY37554.1 - 2.7e-65 219.1 1.3 3.1e-65 218.9 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribonucleas_3_3 PF14622.6 CBY37554.1 - 0.024 14.8 0.1 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like LrgB PF04172.16 CBY37554.1 - 0.12 11.9 2.4 0.079 12.5 0.3 1.7 2 0 0 2 2 2 0 LrgB-like family MH2 PF03166.14 CBY37556.1 - 1.3e-13 51.6 1.6 2.5e-13 50.7 0.1 2.1 2 1 0 2 2 2 1 MH2 domain MH1 PF03165.16 CBY37556.1 - 2e-07 31.2 0.3 4.3e-07 30.1 0.3 1.7 1 0 0 1 1 1 1 MH1 domain RL10P_insert PF17777.1 CBY37556.1 - 0.093 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P Peptidase_C2 PF00648.21 CBY37557.1 - 0.0081 15.2 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Band_7 PF01145.25 CBY37559.1 - 2.5e-07 30.9 0.0 3.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family TspO_MBR PF03073.15 CBY37559.1 - 0.0094 16.0 0.2 0.013 15.6 0.2 1.4 1 1 0 1 1 1 1 TspO/MBR family BatA PF07584.11 CBY37559.1 - 0.031 14.6 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal Nup96 PF12110.8 CBY37560.1 - 2.9e-57 194.0 0.0 4e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Homeobox_KN PF05920.11 CBY37561.1 - 1.9e-15 56.5 0.0 4.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY37561.1 - 5e-08 32.7 0.9 7.6e-08 32.1 0.9 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CBY37561.1 - 0.02 14.4 0.2 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez IMPa_N_2 PF18650.1 CBY37561.1 - 0.12 11.7 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain CP12 PF02672.15 CBY37563.1 - 1.2 10.0 3.7 1.7 9.4 0.9 2.3 2 1 0 2 2 2 0 CP12 domain Fibrinogen_C PF00147.18 CBY37564.1 - 7.4e-25 88.0 0.2 1.1e-24 87.5 0.2 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3829 PF12889.7 CBY37564.1 - 1.7e-05 24.5 1.1 2.7e-05 23.8 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) RPW8 PF05659.11 CBY37564.1 - 0.012 15.4 3.4 0.025 14.3 1.3 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cauli_AT PF03233.13 CBY37564.1 - 0.016 15.1 4.7 0.15 11.9 2.3 2.2 1 1 1 2 2 2 0 Aphid transmission protein UPF0242 PF06785.11 CBY37564.1 - 0.026 14.6 2.4 0.04 14.0 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mucin PF01456.17 CBY37564.1 - 0.058 13.4 4.3 0.1 12.6 4.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Syntaxin-6_N PF09177.11 CBY37564.1 - 0.088 13.4 1.8 0.19 12.3 1.8 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 CBY37564.1 - 0.097 12.7 5.7 1.1 9.3 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 CBY37564.1 - 0.14 12.4 4.7 0.41 10.9 4.3 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF241 PF03087.14 CBY37564.1 - 0.22 11.3 3.0 1.3 8.8 1.6 2.3 2 1 1 3 3 2 0 Arabidopsis protein of unknown function Tweety PF04906.13 CBY37564.1 - 0.24 10.0 1.2 0.35 9.5 0.6 1.5 1 1 0 1 1 1 0 Tweety DUF948 PF06103.11 CBY37564.1 - 0.25 11.6 2.5 0.95 9.8 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CBY37564.1 - 0.36 11.3 2.4 8.1 7.0 0.9 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 CBY37564.1 - 0.37 11.1 3.2 0.71 10.2 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FliD_N PF02465.18 CBY37564.1 - 0.56 10.9 3.3 0.45 11.3 0.4 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 CBY37564.1 - 1.1 8.5 3.7 1.5 8.0 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Carb_anhydrase PF00194.21 CBY37569.1 - 2.3e-52 178.0 0.1 2.9e-52 177.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RA PF00788.23 CBY37569.1 - 0.006 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Thioredoxin PF00085.20 CBY37570.1 - 1.8e-63 211.0 0.0 1.5e-30 105.2 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY37570.1 - 3e-11 43.7 0.8 0.0022 18.4 0.0 4.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY37570.1 - 2.2e-09 37.5 0.0 0.11 12.9 0.0 4.5 3 2 0 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 CBY37570.1 - 3.2e-08 33.3 0.0 0.0012 18.3 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CBY37570.1 - 1.3e-07 31.7 0.0 0.00052 20.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY37570.1 - 1.5e-05 24.9 0.1 0.016 15.2 0.0 3.0 4 0 0 4 4 4 2 AhpC/TSA family TraF PF13728.6 CBY37570.1 - 0.00048 20.0 0.0 0.34 10.7 0.0 3.3 3 1 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 CBY37570.1 - 0.0014 18.5 0.0 1.5 8.7 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CBY37570.1 - 0.0016 18.7 0.6 1.3 9.2 0.1 4.0 3 2 1 4 4 4 1 Thioredoxin Thioredoxin_3 PF13192.6 CBY37570.1 - 0.0031 17.5 0.0 3.9 7.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_5 PF13743.6 CBY37570.1 - 0.0037 17.0 0.0 9.6 5.8 0.0 4.2 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_9 PF14595.6 CBY37570.1 - 0.042 13.6 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 CBY37570.1 - 0.13 12.2 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE adh_short_C2 PF13561.6 CBY37571.1 - 1.8e-44 152.1 0.1 2.2e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY37571.1 - 1.7e-42 145.1 2.2 2.2e-42 144.8 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBY37571.1 - 2.3e-13 50.4 0.3 3.2e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 CBY37571.1 - 8.1e-05 23.1 0.2 0.00016 22.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CBY37571.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CBY37571.1 - 0.0021 17.3 0.3 0.01 15.0 0.3 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NanE PF04131.14 CBY37571.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase 3HCDH_N PF02737.18 CBY37571.1 - 0.034 14.0 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY37571.1 - 0.055 12.9 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_C1 PF00112.23 CBY37572.1 - 7.5e-33 114.5 0.3 8.7e-33 114.2 0.3 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBY37572.1 - 0.00087 18.2 0.6 0.0011 17.8 0.6 1.1 1 0 0 1 1 1 1 Peptidase C1-like family SH3BP5 PF05276.14 CBY37573.1 - 0.0012 18.7 19.9 0.0028 17.5 19.9 1.5 1 1 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) YkyA PF10368.9 CBY37573.1 - 0.0024 17.6 24.3 0.0024 17.5 15.7 2.1 1 1 1 2 2 2 1 Putative cell-wall binding lipoprotein DUF1845 PF08900.11 CBY37573.1 - 0.031 14.0 2.2 0.031 14.0 2.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF1845) Arabinose_Isome PF02610.15 CBY37573.1 - 0.046 12.9 2.8 0.051 12.8 2.8 1.3 1 0 0 1 1 1 0 L-arabinose isomerase ApoO PF09769.9 CBY37573.1 - 0.048 13.6 9.6 3.6 7.6 0.1 3.1 1 1 2 3 3 3 0 Apolipoprotein O BAR_3 PF16746.5 CBY37573.1 - 0.062 13.0 15.8 0.62 9.7 1.4 2.2 1 1 1 2 2 2 0 BAR domain of APPL family DUF4845 PF16137.5 CBY37573.1 - 0.084 13.7 1.9 0.24 12.3 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) DUF1451 PF07295.11 CBY37573.1 - 0.096 12.7 19.8 0.12 12.4 3.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF4200 PF13863.6 CBY37573.1 - 0.12 12.7 32.8 0.032 14.6 25.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 CBY37573.1 - 0.17 11.4 19.8 0.22 11.1 19.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 CBY37573.1 - 0.28 11.5 30.2 0.12 12.6 13.3 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 DUF2461 PF09365.10 CBY37573.1 - 0.28 11.1 4.8 0.33 10.9 0.8 2.4 1 1 2 3 3 3 0 Conserved hypothetical protein (DUF2461) FUSC PF04632.12 CBY37573.1 - 0.39 9.2 12.3 0.61 8.6 12.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2433 PF10360.9 CBY37573.1 - 0.51 10.4 3.7 0.39 10.8 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) V-ATPase_G_2 PF16999.5 CBY37573.1 - 0.63 10.5 22.5 3.3 8.2 3.7 3.1 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit CEP63 PF17045.5 CBY37573.1 - 0.76 9.6 27.7 12 5.7 4.1 2.9 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa Laminin_II PF06009.12 CBY37573.1 - 0.76 9.8 20.8 1.1 9.3 3.9 2.4 1 1 0 2 2 2 0 Laminin Domain II HrpB7 PF09486.10 CBY37573.1 - 1.1 9.7 25.8 0.4 11.0 2.4 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF489 PF04356.12 CBY37573.1 - 1.1 9.3 13.0 0.19 11.7 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DLP_helical PF18709.1 CBY37573.1 - 1.1 8.4 17.6 2.8 7.1 17.6 1.8 1 1 0 1 1 1 0 Dynamin-like helical domain HMMR_N PF15905.5 CBY37573.1 - 1.2 8.6 28.6 17 4.8 28.7 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4226 PF10774.9 CBY37573.1 - 1.2 9.5 17.4 2.9 8.2 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) TMPIT PF07851.13 CBY37573.1 - 1.4 8.1 21.0 0.69 9.1 3.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 CBY37573.1 - 1.4 9.2 11.8 48 4.3 9.5 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 CBY37573.1 - 1.5 8.9 13.9 1 9.4 4.3 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CBY37573.1 - 1.7 8.0 25.5 94 2.2 25.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 CBY37573.1 - 1.9 8.9 25.5 3.2 8.1 20.6 1.9 1 1 1 2 2 2 0 Fez1 FPP PF05911.11 CBY37573.1 - 2 6.5 25.2 0.13 10.4 12.5 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fib_alpha PF08702.10 CBY37573.1 - 2.1 8.5 20.1 6.8 6.9 8.6 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CBY37573.1 - 2.6 8.6 22.4 23 5.6 12.1 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF641 PF04859.12 CBY37573.1 - 2.8 8.3 25.3 7.3 6.9 2.0 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CBY37573.1 - 3.7 6.4 27.8 10 4.9 27.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.14 CBY37573.1 - 4.1 7.7 33.6 3.3 8.0 9.7 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ECH_2 PF16113.5 CBY37573.1 - 4.5 6.7 12.4 5.6 6.4 12.4 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase AAA_13 PF13166.6 CBY37573.1 - 4.5 5.8 20.7 7 5.1 20.7 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 CBY37573.1 - 5.1 7.2 31.3 17 5.5 7.8 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 CBY37573.1 - 5.5 4.8 16.2 7.1 4.4 16.2 1.1 1 0 0 1 1 1 0 Prominin DUF2009 PF09418.10 CBY37573.1 - 6.1 5.8 9.9 4.1 6.4 8.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) DUF1359 PF07097.11 CBY37573.1 - 6.6 7.0 9.2 3.5 7.9 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1359) DUF98 PF01947.16 CBY37573.1 - 6.7 6.7 10.4 1 9.3 2.5 2.7 1 1 2 3 3 3 0 p-hydroxybenzoic acid synthase FlaC_arch PF05377.11 CBY37573.1 - 7.5 7.0 14.1 7.6 7.0 1.5 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Ku_C PF03730.14 CBY37573.1 - 9.3 7.0 14.0 1.4 9.6 7.2 2.4 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm Phage_Mu_Gam PF07352.12 CBY37573.1 - 9.9 6.1 20.8 3.3 7.6 1.3 3.1 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein NT-C2 PF10358.9 CBY37574.1 - 1.2e-15 57.5 0.4 1.8e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 CBY37574.1 - 7e-05 23.1 0.2 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain zf-C2H2_4 PF13894.6 CBY37575.1 - 9.1e-06 26.1 22.5 0.014 16.1 1.6 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY37575.1 - 4.4e-05 23.7 18.7 0.00042 20.6 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY37575.1 - 0.0016 18.8 0.7 0.0016 18.8 0.7 4.0 3 1 0 3 3 3 1 Zinc-finger double domain zinc_ribbon_15 PF17032.5 CBY37575.1 - 0.076 13.8 1.1 0.076 13.8 1.1 2.7 3 0 0 3 3 3 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 CBY37575.1 - 0.076 13.7 9.5 3.8 8.2 0.9 3.6 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 CBY37575.1 - 10 6.6 17.2 50 4.3 0.2 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Bac_surface_Ag PF01103.23 CBY37576.1 - 3.9e-19 69.3 3.8 5.1e-19 68.9 3.8 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 CBY37576.1 - 0.021 14.3 0.1 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Ras PF00071.22 CBY37578.1 - 1e-56 191.0 0.2 1.2e-56 190.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37578.1 - 2.1e-20 73.1 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37578.1 - 1.6e-08 34.2 0.1 1.8e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY37578.1 - 6.2e-05 22.6 0.2 0.00012 21.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY37578.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY37578.1 - 0.0018 18.2 0.7 1.5 8.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CBY37578.1 - 0.076 12.8 0.2 3.9 7.2 0.0 2.2 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1515 PF07439.11 CBY37578.1 - 0.099 12.7 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) G-alpha PF00503.20 CBY37578.1 - 0.18 10.9 0.0 15 4.6 0.0 2.2 1 1 0 2 2 2 0 G-protein alpha subunit FAIM1 PF06905.13 CBY37579.1 - 1.4e-59 200.7 0.4 1.7e-59 200.4 0.4 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Adenyl_transf PF04439.12 CBY37579.1 - 0.085 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Lactamase_B_2 PF12706.7 CBY37580.1 - 6.2e-16 58.5 0.0 1e-07 31.7 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBY37580.1 - 2.3e-05 24.5 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DOMON PF03351.17 CBY37581.1 - 1.4e-12 47.9 0.2 2.2e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 CBY37581.1 - 8.4e-08 32.4 1.1 8.4e-08 32.4 1.1 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.11 CBY37581.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 2.4 1 1 1 2 2 2 1 Tight junction protein, Claudin-like PMP22_Claudin PF00822.20 CBY37581.1 - 0.0057 16.5 0.1 0.0057 16.5 0.1 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family ODV-E18 PF10717.9 CBY37581.1 - 0.12 12.2 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4079 PF13301.6 CBY37581.1 - 0.15 12.3 5.9 0.026 14.7 1.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CBY37581.1 - 1.2 8.7 11.8 12 5.5 11.8 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 XK-related PF09815.9 CBY37582.1 - 1.4e-88 297.2 31.9 1.7e-88 297.0 31.9 1.1 1 0 0 1 1 1 1 XK-related protein Sarcoglycan_2 PF05510.13 CBY37582.1 - 0.00044 19.2 0.0 0.00063 18.6 0.0 1.3 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon Orf78 PF06024.12 CBY37582.1 - 0.014 15.6 1.1 0.092 13.0 0.5 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 CBY37582.1 - 1.4 8.5 10.2 0.47 10.1 1.5 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) UBX PF00789.20 CBY37583.1 - 1.5e-09 37.9 0.0 4.9e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CBY37583.1 - 4e-06 26.5 0.1 7.9e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CBY37583.1 - 0.044 13.4 0.2 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 TAP C-terminal domain adh_short PF00106.25 CBY37584.1 - 3.5e-07 29.9 0.0 6.8e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY37584.1 - 0.001 18.7 0.0 0.047 13.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HU-CCDC81_euk_1 PF14908.6 CBY37586.1 - 2e-14 53.5 0.1 9.4e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 CBY37586.1 - 1.3e-06 28.5 0.3 4.2e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 CBY37586.1 - 0.00013 22.1 1.9 0.027 14.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial DNA-binding protein TPH PF13868.6 CBY37587.1 - 7.2e-64 215.5 120.5 7.2e-64 215.5 120.5 2.1 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain RITA PF17066.5 CBY37587.1 - 0.071 12.7 0.0 0.071 12.7 0.0 2.2 2 2 1 3 3 3 0 RBPJ-interacting and tubulin associated protein HMG-CoA_red PF00368.18 CBY37589.1 - 2.3e-116 388.8 0.1 3.3e-116 388.3 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HIPIP PF01355.17 CBY37590.1 - 0.0023 18.2 17.5 2.5 8.5 0.3 6.5 6 0 0 6 6 6 4 High potential iron-sulfur protein DUF4729 PF15866.5 CBY37590.1 - 1.9 7.8 25.9 0.18 11.1 0.1 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4729) PrmA PF06325.13 CBY37591.1 - 0.011 15.2 0.2 0.023 14.1 0.1 1.6 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CBY37591.1 - 0.044 13.5 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Tli4_N PF18443.1 CBY37591.1 - 0.072 13.5 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain MTS PF05175.14 CBY37591.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ANTH PF07651.16 CBY37592.1 - 6e-64 215.7 0.3 6e-64 215.7 0.3 1.7 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CBY37592.1 - 5.9e-13 49.0 0.0 9.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain SET PF00856.28 CBY37593.1 - 1e-08 35.7 0.8 2.7e-08 34.4 0.0 2.0 2 1 0 2 2 2 1 SET domain Pkinase PF00069.25 CBY37594.1 - 2.2e-59 201.0 0.0 6.5e-59 199.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37594.1 - 5.2e-36 124.2 0.0 1.2e-35 123.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.16 CBY37594.1 - 2.7e-24 85.1 30.3 2.2e-10 40.5 9.0 4.2 3 0 0 3 3 3 3 Hr1 repeat Kinase-like PF14531.6 CBY37594.1 - 8.5e-06 25.3 1.1 4.5e-05 22.9 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Uds1 PF15456.6 CBY37594.1 - 0.0045 17.2 5.4 0.0045 17.2 5.4 4.2 4 0 0 4 4 4 1 Up-regulated During Septation DUF842 PF05811.13 CBY37594.1 - 2.7 7.7 12.7 8.6 6.1 0.8 3.4 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Piwi PF02171.17 CBY37597.1 - 6.5e-32 111.0 0.0 1.9e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 Piwi domain ArgoL1 PF08699.10 CBY37597.1 - 0.00072 19.2 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 2 Argonaute linker 1 domain ArgoN PF16486.5 CBY37597.1 - 0.0017 19.0 0.0 0.0037 17.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute DUF5320 PF17253.2 CBY37597.1 - 0.0047 18.0 0.1 0.014 16.5 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5320) PAZ PF02170.22 CBY37597.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 PAZ domain DNA_pol_phi PF04931.13 CBY37601.1 - 2.2 6.3 23.2 2.3 6.2 23.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3535 PF12054.8 CBY37602.1 - 4.5e-13 49.2 2.2 2.8e-05 23.6 0.0 5.2 5 1 1 6 6 6 3 Domain of unknown function (DUF3535) Vac14_Fab1_bd PF12755.7 CBY37602.1 - 0.002 18.7 1.2 0.36 11.5 0.0 3.9 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBY37602.1 - 0.019 13.6 1.1 0.049 12.2 0.2 2.2 3 0 0 3 3 3 0 Adaptin N terminal region Dynamin_M PF01031.20 CBY37603.1 - 2.5e-95 319.0 2.6 2.5e-95 319.0 2.6 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CBY37603.1 - 1e-54 185.1 0.2 6.3e-54 182.5 0.0 2.4 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 CBY37603.1 - 2.5e-22 78.8 3.0 7.9e-22 77.2 3.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain PH PF00169.29 CBY37603.1 - 1.7e-10 41.3 0.4 3.8e-10 40.2 0.4 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY37603.1 - 0.00021 21.3 0.0 0.00078 19.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY37603.1 - 0.016 15.6 0.0 0.88 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain ApoO PF09769.9 CBY37603.1 - 0.046 13.7 0.3 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein O DUF2780 PF11075.8 CBY37603.1 - 0.094 12.9 0.2 0.094 12.9 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) RasGAP PF00616.19 CBY37603.1 - 0.58 9.8 3.5 0.45 10.2 1.1 2.1 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase EloA-BP1 PF15870.5 CBY37604.1 - 1.1e-15 58.3 0.1 1.1e-15 58.3 0.1 2.5 2 0 0 2 2 2 1 ElonginA binding-protein 1 MDM10 PF12519.8 CBY37604.1 - 1.4 7.7 8.7 2.1 7.1 8.7 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CHORD PF04968.12 CBY37604.1 - 2.2 9.1 7.0 5.7 7.7 7.0 1.6 1 0 0 1 1 1 0 CHORD CDC45 PF02724.14 CBY37604.1 - 6.5 4.9 15.8 9.6 4.4 15.8 1.3 1 0 0 1 1 1 0 CDC45-like protein MCM3AP_GANP PF16769.5 CBY37604.1 - 9.2 4.4 13.9 13 3.9 13.9 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP CD225 PF04505.12 CBY37608.1 - 2.1e-05 24.6 0.7 0.00055 20.0 0.1 2.3 2 0 0 2 2 2 1 Interferon-induced transmembrane protein DUF2062 PF09835.9 CBY37608.1 - 0.035 14.0 1.6 0.056 13.3 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4190 PF13828.6 CBY37608.1 - 0.12 12.1 2.7 9.1 6.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) zf-MYND PF01753.18 CBY37610.1 - 7.1e-06 26.0 17.6 1.4e-05 25.1 17.6 1.5 1 0 0 1 1 1 1 MYND finger PLC-beta_C PF08703.10 CBY37610.1 - 1.8e-05 24.8 9.1 2.5e-05 24.4 9.1 1.2 1 0 0 1 1 1 1 PLC-beta C terminal DUF1492 PF07374.11 CBY37610.1 - 0.027 14.6 4.8 0.037 14.2 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) Phage_GPO PF05929.11 CBY37610.1 - 0.13 11.9 4.8 0.15 11.6 4.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.13 CBY37610.1 - 0.15 12.6 3.6 0.23 12.1 3.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RRP36 PF06102.12 CBY37610.1 - 0.23 11.4 8.6 0.34 10.9 8.6 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 ParB PF08775.10 CBY37610.1 - 0.26 11.7 7.8 0.48 10.9 7.8 1.4 1 1 0 1 1 1 0 ParB family RNase_J_C PF17770.1 CBY37610.1 - 0.43 11.7 6.1 0.16 13.0 2.4 2.0 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain LMBR1 PF04791.16 CBY37610.1 - 0.8 8.5 2.3 0.84 8.5 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TruD PF01142.18 CBY37611.1 - 2.8e-65 220.8 0.0 1.6e-61 208.4 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) CLASP_N PF12348.8 CBY37612.1 - 1.6e-17 63.8 0.0 6.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal Tti2 PF10521.9 CBY37612.1 - 0.18 11.3 0.0 0.7 9.4 0.0 1.9 2 0 0 2 2 2 0 Tti2 family Lectin_C PF00059.21 CBY37613.1 - 1.9e-22 80.1 10.6 6.1e-10 39.8 4.5 3.7 3 1 0 3 3 3 3 Lectin C-type domain Seryl_tRNA_N PF02403.22 CBY37613.1 - 0.029 14.6 1.3 0.06 13.6 1.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4446 PF14584.6 CBY37613.1 - 0.068 13.2 0.3 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 CBY37613.1 - 0.22 11.6 0.3 0.43 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 CBY37613.1 - 0.25 11.8 2.9 0.54 10.7 2.9 1.5 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins HALZ PF02183.18 CBY37613.1 - 4.5 7.6 6.9 1.5 9.1 3.5 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Kelch_5 PF13854.6 CBY37615.1 - 0.0031 17.5 0.8 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Kelch motif DUF1150 PF06620.11 CBY37617.1 - 0.13 12.4 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) EF-hand_1 PF00036.32 CBY37618.1 - 7.4e-28 94.0 14.5 9.3e-08 31.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY37618.1 - 2e-26 92.2 6.2 3.2e-13 49.9 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY37618.1 - 2.1e-22 77.1 10.5 3.4e-07 29.7 0.0 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CBY37618.1 - 1e-20 73.3 13.1 3.7e-11 42.7 1.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBY37618.1 - 7.1e-16 58.3 0.2 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY37618.1 - 5.3e-06 25.7 17.2 0.00055 19.3 0.7 5.0 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 CBY37618.1 - 1.2e-05 25.1 5.3 0.006 16.5 1.2 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY37618.1 - 0.00016 22.5 0.3 0.1 13.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CBY37618.1 - 0.001 19.3 0.7 0.88 10.0 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CBY37618.1 - 0.0019 18.4 0.2 0.0067 16.6 0.1 1.9 1 1 1 2 2 2 1 Dockerin type I domain SUB1_ProdP9 PF18213.1 CBY37618.1 - 0.0027 17.5 1.3 0.01 15.7 0.3 2.1 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 SurA_N_2 PF13623.6 CBY37618.1 - 0.026 14.4 3.0 3.5 7.5 0.1 2.7 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CBY37618.1 - 0.035 12.7 0.1 0.26 9.8 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.13 CBY37618.1 - 0.038 13.9 0.2 8.4 6.3 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein FlgD PF03963.14 CBY37618.1 - 0.041 14.2 0.1 0.073 13.4 0.1 1.6 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region TerB PF05099.13 CBY37618.1 - 0.072 13.0 3.8 5.9 6.8 0.6 3.0 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CBY37618.1 - 0.13 12.9 2.8 0.13 12.9 0.8 2.0 2 0 0 2 2 2 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CBY37618.1 - 0.24 11.7 4.0 0.45 10.8 1.9 2.0 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Malate_DH PF12434.8 CBY37618.1 - 0.51 10.4 3.7 0.22 11.6 0.8 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme TTL PF03133.15 CBY37619.1 - 9.5e-69 231.8 0.8 3.7e-68 229.8 0.1 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY37619.1 - 1.6e-07 30.8 0.3 2e-05 24.0 0.1 2.9 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY37619.1 - 0.06 12.6 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ntox46 PF15538.6 CBY37619.1 - 0.062 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 46 OstA PF03968.14 CBY37619.1 - 0.089 13.0 0.9 0.32 11.2 0.9 2.1 1 1 0 1 1 1 0 OstA-like protein Fibrinogen_C PF00147.18 CBY37620.1 - 2.5e-40 138.6 17.6 8.4e-29 101.0 9.9 4.0 2 2 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 CBY37620.1 - 2e-06 28.1 0.2 4.9e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PEP-utilisers_N PF05524.13 CBY37620.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TSP_1 PF00090.19 CBY37621.1 - 4e-11 42.9 10.4 4e-11 42.9 10.4 2.8 3 1 0 3 3 3 1 Thrombospondin type 1 domain CarboxypepD_reg PF13620.6 CBY37621.1 - 2.5e-08 34.0 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CBY37621.1 - 8.6e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Ig_3 PF13927.6 CBY37621.1 - 0.00043 20.8 0.3 0.0036 17.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain I-set PF07679.16 CBY37621.1 - 0.074 13.1 0.0 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Immunoglobulin I-set domain zf-C3HC4_2 PF13923.6 CBY37622.1 - 9e-05 22.2 16.1 9e-05 22.2 16.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY37622.1 - 0.00096 19.0 11.2 0.0018 18.1 11.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY37622.1 - 0.0012 18.8 16.5 0.0031 17.4 16.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY37622.1 - 0.0029 17.6 9.2 0.0087 16.1 9.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY37622.1 - 0.0072 16.2 16.7 0.0072 16.2 16.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY37622.1 - 0.0092 16.1 12.0 0.033 14.4 12.0 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBY37622.1 - 0.011 16.1 14.9 0.011 16.1 14.9 2.0 2 0 0 2 2 2 0 Ring finger domain ZapB PF06005.12 CBY37622.1 - 0.023 15.1 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 CBY37622.1 - 0.028 15.0 6.0 0.034 14.8 6.0 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PCNP PF15473.6 CBY37622.1 - 0.08 13.7 0.2 0.11 13.2 0.2 1.3 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family zf-RING_4 PF14570.6 CBY37622.1 - 0.19 11.5 13.8 0.85 9.5 13.5 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS91 PF14319.6 CBY37622.1 - 0.39 10.8 11.9 0.098 12.7 6.8 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zinc-ribbons_6 PF07191.12 CBY37622.1 - 0.66 10.0 12.9 0.28 11.2 9.9 1.9 2 0 0 2 2 2 0 zinc-ribbons zf-UDP PF14569.6 CBY37622.1 - 0.66 10.1 9.5 12 6.1 10.1 2.2 1 1 1 2 2 2 0 Zinc-binding RING-finger Gly-zipper_Omp PF13488.6 CBY37623.1 - 0.053 13.5 3.1 0.053 13.5 3.1 1.9 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 CBY37623.1 - 0.16 11.8 5.8 0.34 10.7 5.8 1.5 1 0 0 1 1 1 0 Glycine-zipper domain PTE PF02126.18 CBY37625.1 - 2.1e-56 191.5 0.0 2.5e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family DUF4434 PF14488.6 CBY37625.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Aida_N PF08910.10 CBY37626.1 - 0.32 11.4 9.4 5.7 7.4 0.2 3.6 3 1 0 3 3 3 0 Aida N-terminus DUF883 PF05957.13 CBY37626.1 - 8.4 7.1 10.5 2.9 8.5 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.21 CBY37627.1 - 6.7e-30 104.2 0.3 2.9e-16 59.6 0.0 3.1 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 CBY37627.1 - 4e-20 71.8 0.3 7.6e-20 70.9 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 CBY37627.1 - 3.3e-13 49.6 0.1 6.4e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Pyr_redox_2 PF07992.14 CBY37627.1 - 0.01 15.1 0.1 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBY37627.1 - 0.066 13.8 0.2 7.8 7.1 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 CBY37628.1 - 9.7e-77 258.3 1.8 1.3e-75 254.6 1.9 2.4 2 1 0 2 2 2 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 CBY37628.1 - 4.8e-56 189.9 0.0 6.4e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_UFD PF09358.10 CBY37628.1 - 2e-30 105.3 0.1 6.1e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin fold domain COesterase PF00135.28 CBY37629.1 - 1.7e-91 307.6 0.0 2.3e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY37629.1 - 9.5e-14 51.7 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY37629.1 - 0.00018 21.1 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CBY37629.1 - 0.021 13.7 0.1 0.056 12.3 0.0 1.7 2 1 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CBY37629.1 - 0.032 14.8 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 CBY37630.1 - 1.2e-28 99.8 0.2 1.5e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37630.1 - 2.2e-21 76.3 0.1 3.2e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37630.1 - 2.1e-13 50.1 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY37630.1 - 3.2e-05 23.6 0.1 0.00035 20.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY37630.1 - 7.2e-05 22.7 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY37630.1 - 0.0019 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY37630.1 - 0.056 13.0 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B MnmE_helical PF12631.7 CBY37630.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain AAA_29 PF13555.6 CBY37630.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIP49_C PF12260.8 CBY37632.1 - 0.0013 18.4 6.1 0.0023 17.6 6.1 1.5 1 1 0 1 1 1 1 Protein-kinase domain of FAM69 DUF2420 PF10336.9 CBY37632.1 - 0.15 12.1 2.0 3.8 7.6 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2420) Coa1 PF08695.10 CBY37633.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Ank_2 PF12796.7 CBY37634.1 - 0.03 14.9 0.0 0.88 10.2 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) bZIP_1 PF00170.21 CBY37635.1 - 8.5e-14 51.4 16.0 1.3e-13 50.8 16.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY37635.1 - 2e-07 31.0 16.8 2.9e-07 30.5 14.6 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY37635.1 - 2.7e-05 24.6 11.1 4.1e-05 24.0 11.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor ZapB PF06005.12 CBY37635.1 - 0.0057 17.1 8.7 0.0057 17.1 8.7 1.8 1 1 1 2 2 2 1 Cell division protein ZapB BLOC1_2 PF10046.9 CBY37635.1 - 0.0074 16.6 2.3 0.013 15.8 2.3 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CBY37635.1 - 0.017 14.0 6.9 0.021 13.7 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RF-1 PF00472.20 CBY37635.1 - 0.039 13.9 5.0 0.066 13.1 5.1 1.4 1 1 0 1 1 1 0 RF-1 domain HAUS6_N PF14661.6 CBY37635.1 - 0.039 13.5 3.2 0.04 13.5 3.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.9 CBY37635.1 - 0.052 12.6 5.7 0.063 12.3 5.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_G5 PF04599.12 CBY37635.1 - 0.065 12.2 1.5 0.062 12.3 1.5 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein PspA_IM30 PF04012.12 CBY37635.1 - 0.065 12.8 9.3 0.18 11.3 9.3 1.7 1 1 0 1 1 1 0 PspA/IM30 family Spc24 PF08286.11 CBY37635.1 - 0.098 12.9 5.7 0.081 13.2 4.3 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prominin PF05478.11 CBY37635.1 - 0.12 10.3 2.1 0.14 10.1 2.1 1.0 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.8 CBY37635.1 - 0.16 11.4 11.1 0.21 11.0 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YabA PF06156.13 CBY37635.1 - 0.37 11.4 6.5 0.36 11.5 5.4 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 CBY37635.1 - 0.59 9.9 10.3 0.12 12.2 4.0 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF737 PF05300.11 CBY37635.1 - 1.9 8.8 10.6 3.5 7.9 10.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) XhlA PF10779.9 CBY37635.1 - 3 8.1 5.2 1.4 9.2 2.6 1.7 1 1 1 2 2 2 0 Haemolysin XhlA Fe-ADH PF00465.19 CBY37636.1 - 3e-96 322.4 0.0 3.5e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBY37636.1 - 8.6e-12 45.3 0.0 6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Syndecan PF01034.20 CBY37637.1 - 1e-07 31.8 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain MGAT2 PF05060.14 CBY37638.1 - 3.5e-87 292.7 1.8 4.4e-87 292.4 1.8 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) Methyltransf_10 PF05971.12 CBY37639.1 - 1.3e-08 34.5 0.0 1.6e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Med23 PF11573.8 CBY37640.1 - 1.9e-116 390.3 24.4 2.1e-116 390.2 24.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 23 Tektin PF03148.14 CBY37641.1 - 6.7e-21 74.5 25.2 2.1e-20 72.9 25.2 1.7 1 1 0 1 1 1 1 Tektin family Dynactin_p22 PF07426.11 CBY37641.1 - 0.033 14.1 3.0 0.12 12.3 0.2 2.9 3 0 0 3 3 3 0 Dynactin subunit p22 DASH_Dad2 PF08654.10 CBY37641.1 - 0.084 13.3 2.3 0.11 12.9 0.2 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad2 YabA PF06156.13 CBY37641.1 - 2.7 8.7 12.2 1.1 9.9 0.2 3.6 4 1 0 4 4 4 0 Initiation control protein YabA WD40 PF00400.32 CBY37642.1 - 2.4e-21 75.7 21.8 0.0021 18.9 0.0 9.7 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37642.1 - 7.3e-10 39.0 0.1 0.0017 18.6 0.0 6.5 4 1 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 CBY37642.1 - 0.003 17.2 0.1 0.011 15.3 0.1 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Ge1_WD40 PF16529.5 CBY37642.1 - 0.011 14.7 0.1 0.25 10.3 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 CBY37642.1 - 0.03 14.5 0.1 5.6 7.3 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Reg_prop PF07494.11 CBY37642.1 - 0.14 12.5 1.1 23 5.7 0.1 4.2 4 0 0 4 4 4 0 Two component regulator propeller TLE_N PF03920.15 CBY37643.1 - 2.9e-56 189.1 0.4 4.4e-56 188.6 0.4 1.2 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain WD40 PF00400.32 CBY37643.1 - 7.4e-20 70.9 17.6 0.00021 22.0 0.6 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37643.1 - 4.8e-07 30.0 0.1 0.13 12.6 0.0 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Sec34 PF04136.15 CBY37643.1 - 0.029 14.3 0.3 0.051 13.5 0.3 1.3 1 0 0 1 1 1 0 Sec34-like family RAB3GAP2_N PF14655.6 CBY37643.1 - 0.072 12.3 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 CBY37643.1 - 0.15 10.5 0.0 3.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Dicty_REP PF05086.12 CBY37644.1 - 0.027 12.5 1.3 0.032 12.2 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5435 PF17503.2 CBY37644.1 - 0.14 11.9 2.2 0.2 11.4 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Mucin PF01456.17 CBY37644.1 - 4.8 7.2 25.9 8.4 6.4 25.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BSP_II PF05432.11 CBY37644.1 - 7.4 6.2 12.7 15 5.2 12.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Glyco_hydro_16 PF00722.21 CBY37645.1 - 5.7e-25 87.8 1.1 5.7e-25 87.8 1.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4504 PF14953.6 CBY37646.1 - 2e-09 37.3 0.1 2.5e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) dsrm PF00035.26 CBY37647.1 - 0.0014 19.3 2.9 0.0051 17.5 0.0 3.0 3 0 0 3 3 3 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY37647.1 - 0.048 13.9 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1366 PF07104.11 CBY37647.1 - 0.57 9.9 2.9 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1366) F5_F8_type_C PF00754.25 CBY37648.1 - 7e-08 32.6 0.2 9.3e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain 7tm_2 PF00002.24 CBY37649.1 - 3.6e-53 180.4 16.7 5.2e-53 179.9 16.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPS PF01825.21 CBY37649.1 - 1.8e-15 57.2 5.8 5.7e-15 55.6 5.8 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Gal_Lectin PF02140.18 CBY37649.1 - 1.4e-08 35.1 0.1 6.8e-08 32.8 0.1 2.3 1 0 0 1 1 1 1 Galactose binding lectin domain INTAP PF16617.5 CBY37650.1 - 0.04 14.3 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region SCIMP PF15050.6 CBY37651.1 - 0.0017 18.8 0.1 0.082 13.4 0.0 2.2 2 0 0 2 2 2 1 SCIMP protein LapA_dom PF06305.11 CBY37651.1 - 0.0042 16.9 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EVC2_like PF12297.8 CBY37651.1 - 0.0088 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Ellis van Creveld protein 2 like protein TPK_catalytic PF04263.16 CBY37652.1 - 9.5e-29 99.9 0.0 1.3e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CBY37652.1 - 1.7e-13 50.0 0.0 2.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Vhr1 PF04001.13 CBY37652.1 - 0.2 12.0 0.0 1 9.7 0.0 2.1 3 0 0 3 3 3 0 Transcription factor Vhr1 Zona_pellucida PF00100.23 CBY37654.1 - 0.0032 17.3 2.5 0.0041 17.0 2.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Cu2_monooxygen PF01082.20 CBY37655.1 - 3.2e-24 85.6 0.0 6.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 CBY37655.1 - 0.00034 20.2 0.0 0.00069 19.2 0.0 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Thioredoxin PF00085.20 CBY37659.1 - 5.5e-63 209.4 0.1 1.5e-28 98.8 0.0 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CBY37659.1 - 6e-42 143.6 0.1 6.8e-33 114.1 0.3 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBY37659.1 - 2.3e-12 47.1 0.0 0.00024 21.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY37659.1 - 4.4e-09 36.1 0.0 0.0097 15.3 0.0 3.1 3 0 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY37659.1 - 4.9e-08 33.4 2.3 0.029 14.8 0.0 4.4 3 3 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY37659.1 - 7e-08 32.4 0.1 0.00043 20.2 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 CBY37659.1 - 4e-07 29.9 1.4 0.14 11.9 0.0 3.5 2 1 1 3 3 3 2 Redoxin Thioredoxin_7 PF13899.6 CBY37659.1 - 2.8e-06 27.4 0.1 0.13 12.4 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 CBY37659.1 - 0.00029 21.0 0.2 3.6 7.7 0.0 4.0 3 1 1 4 4 4 1 ERp29, N-terminal domain TraF PF13728.6 CBY37659.1 - 0.033 14.0 0.0 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CBY37659.1 - 0.43 10.8 2.0 9.4 6.5 0.0 3.5 4 0 0 4 4 4 0 Glutaredoxin Sulfotransfer_1 PF00685.27 CBY37660.1 - 4.9e-05 23.0 1.8 0.00059 19.4 1.8 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY37660.1 - 0.0049 17.3 0.1 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase family Hexokinase_1 PF00349.21 CBY37661.1 - 0.0066 16.4 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Nic96 PF04097.14 CBY37661.1 - 0.046 12.2 0.0 0.049 12.1 0.0 1.0 1 0 0 1 1 1 0 Nup93/Nic96 DUF4533 PF15047.6 CBY37661.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Hexokinase_2 PF03727.16 CBY37662.1 - 3.8e-79 265.5 0.0 5.2e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CBY37662.1 - 7.9e-65 218.5 0.0 1.2e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RhoGEF PF00621.20 CBY37663.1 - 3.5e-22 79.5 0.2 3.5e-22 79.5 0.2 3.4 2 2 1 3 3 3 1 RhoGEF domain Spectrin PF00435.21 CBY37663.1 - 1.1e-07 32.3 0.2 1.1e-07 32.3 0.2 4.2 4 0 0 4 4 4 1 Spectrin repeat PH_10 PF15411.6 CBY37663.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain McrBC PF10117.9 CBY37663.1 - 0.0063 15.7 1.1 0.02 14.0 0.2 2.2 2 0 0 2 2 2 1 McrBC 5-methylcytosine restriction system component DUF1845 PF08900.11 CBY37663.1 - 0.016 15.0 1.4 0.031 14.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) Fib_alpha PF08702.10 CBY37663.1 - 0.018 15.3 5.3 3.1 8.0 0.1 3.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 CBY37663.1 - 0.091 13.2 6.6 1.6 9.2 0.2 3.4 3 0 0 3 3 3 0 Snapin/Pallidin BORCS7 PF16088.5 CBY37663.1 - 2.2 8.6 4.7 27 5.1 0.1 3.1 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 P4Ha_N PF08336.11 CBY37663.1 - 2.5 8.1 6.7 1.7 8.6 0.1 3.1 2 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cytochrom_NNT PF03264.14 CBY37663.1 - 6.1 6.5 7.4 0.74 9.5 0.7 2.5 3 0 0 3 3 3 0 NapC/NirT cytochrome c family, N-terminal region UQ_con PF00179.26 CBY37664.1 - 3.1e-45 153.3 0.0 3.8e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY37664.1 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY37664.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CBY37664.1 - 0.03 14.6 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain DnaB_bind PF10410.9 CBY37666.1 - 0.028 14.6 2.3 0.044 14.0 0.4 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF2606 PF10794.9 CBY37666.1 - 0.03 14.1 0.3 0.047 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Pec_lyase_N PF04431.13 CBY37666.1 - 0.083 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Pectate lyase, N terminus DUF4706 PF15797.5 CBY37666.1 - 1.4 9.5 12.9 0.73 10.4 0.2 3.9 1 1 2 4 4 4 0 Domain of unknown function (DUF4706) Integrin_alpha2 PF08441.12 CBY37667.1 - 1.1e-55 189.4 4.2 3e-42 145.1 0.9 2.2 1 1 1 2 2 2 2 Integrin alpha FG-GAP PF01839.23 CBY37667.1 - 4.3e-19 68.3 4.7 3.8e-05 23.7 0.1 3.5 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 CBY37667.1 - 7.9e-16 58.4 1.6 4e-11 43.3 0.4 2.8 2 0 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 CBY37667.1 - 0.062 13.3 0.2 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PRY PF13765.6 CBY37667.1 - 0.38 10.4 1.5 1 9.1 0.1 2.5 3 0 0 3 3 3 0 SPRY-associated domain AhpC-TSA PF00578.21 CBY37669.1 - 1.4e-34 118.6 0.0 1.9e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY37669.1 - 4.7e-15 55.6 0.0 5.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBY37669.1 - 2.1e-13 49.8 0.1 3.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CBY37669.1 - 0.084 12.8 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 SCO1/SenC 7tm_3 PF00003.22 CBY37672.1 - 2e-06 27.7 6.5 2.8e-06 27.3 6.5 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR TMEM70 PF06979.12 CBY37672.1 - 0.0071 16.8 0.6 0.015 15.7 0.6 1.5 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Lipase PF00151.19 CBY37673.1 - 3.5e-56 191.0 0.0 6.1e-56 190.1 0.0 1.4 1 1 0 1 1 1 1 Lipase DUF900 PF05990.12 CBY37673.1 - 3.6e-05 23.4 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 CBY37673.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 CBY37673.1 - 0.032 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 CBY37673.1 - 0.074 13.6 1.0 0.88 10.1 0.4 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 CBY37673.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase PF00151.19 CBY37674.1 - 5.1e-54 183.8 3.4 7.8e-54 183.2 3.4 1.3 1 1 0 1 1 1 1 Lipase DUF900 PF05990.12 CBY37674.1 - 7.2e-06 25.7 0.2 9.4e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 CBY37674.1 - 2e-05 24.2 0.1 2.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 CBY37674.1 - 8.4e-05 22.2 0.1 0.00046 19.8 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CBY37674.1 - 0.0038 17.1 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY37674.1 - 0.0049 17.5 0.0 0.0074 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY37674.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 CBY37674.1 - 0.046 13.4 0.1 0.082 12.5 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CBY37674.1 - 0.056 13.2 0.2 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 PGAP1-like protein VirJ PF06057.11 CBY37674.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3763 PF12592.8 CBY37674.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) DOMON PF03351.17 CBY37675.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 DOMON domain Myofilin PF15929.5 CBY37677.1 - 0.019 15.4 0.1 0.047 14.1 0.1 1.6 1 0 0 1 1 1 0 Myofilin PuR_N PF09182.10 CBY37677.1 - 0.11 12.4 0.1 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Lipase PF00151.19 CBY37679.1 - 1.2e-41 143.2 0.0 7.6e-21 74.8 0.0 2.1 2 0 0 2 2 2 2 Lipase DUF900 PF05990.12 CBY37679.1 - 7.5e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CBY37679.1 - 8.2e-05 23.3 0.0 0.00013 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CBY37679.1 - 0.004 16.7 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CBY37679.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 CBY37679.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase AAA_lid_3 PF17862.1 CBY37680.1 - 9.1e-10 38.2 1.2 9.1e-10 38.2 1.2 2.5 2 1 1 3 3 3 1 AAA+ lid domain AAA PF00004.29 CBY37680.1 - 1.4e-09 38.5 0.0 5.1e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBY37680.1 - 1.5e-05 24.8 1.2 2.8e-05 24.0 0.1 1.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain DUF2152 PF10222.9 CBY37682.1 - 6.3e-60 203.2 0.2 1.5e-59 201.9 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.15 CBY37682.1 - 0.0063 16.2 0.1 0.0089 15.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pro_isomerase PF00160.21 CBY37683.1 - 2.1e-36 125.6 0.0 2.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-C2H2 PF00096.26 CBY37684.1 - 1.1e-14 54.0 38.8 4.5e-06 26.8 1.7 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY37684.1 - 4e-14 52.3 27.5 2.8e-06 27.5 0.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY37684.1 - 1.2e-08 35.1 34.1 0.003 18.3 1.1 6.2 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY37684.1 - 9.5e-05 22.6 18.8 0.033 14.5 0.7 4.9 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CBY37684.1 - 0.00077 20.1 8.7 0.063 14.0 0.4 2.2 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats DUF3268 PF11672.8 CBY37684.1 - 0.0013 19.1 1.0 0.0037 17.6 1.0 1.8 1 1 0 1 1 1 1 zinc-finger-containing domain zf-C2H2_6 PF13912.6 CBY37684.1 - 0.0025 17.7 21.4 0.018 15.1 0.4 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 CBY37684.1 - 0.014 15.7 16.5 0.065 13.7 0.5 5.1 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CBY37684.1 - 0.054 13.3 0.4 0.054 13.3 0.4 4.3 4 1 0 4 4 4 0 C2H2-type zinc-finger domain IBR PF01485.21 CBY37684.1 - 0.063 13.5 1.4 0.063 13.5 1.4 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf_ZIC PF18366.1 CBY37684.1 - 0.071 13.2 8.9 1.2 9.3 0.1 3.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-Di19 PF05605.12 CBY37684.1 - 0.2 12.0 12.2 0.33 11.3 1.7 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.10 CBY37684.1 - 0.51 11.0 5.7 0.23 12.1 0.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2HE PF16278.5 CBY37684.1 - 3 8.4 15.1 0.19 12.2 1.3 3.8 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger Actin_micro PF17003.5 CBY37684.1 - 4 6.5 6.7 4.6 6.3 0.4 2.2 2 0 0 2 2 2 0 Putative actin-like family ASH PF15780.5 CBY37685.1 - 2.1e-07 31.0 1.5 1.2e-05 25.5 0.2 2.7 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBY37685.1 - 0.0032 17.6 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Flagellar-associated PapD-like VCBS PF13517.6 CBY37686.1 - 6.8e-08 33.0 8.8 0.052 14.1 0.2 3.9 3 1 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBY37686.1 - 0.18 12.0 7.2 7.3 6.8 0.0 4.0 4 0 0 4 4 4 0 FG-GAP repeat CP2 PF04516.15 CBY37687.1 - 0.00033 20.0 1.7 0.00044 19.6 0.0 2.0 2 0 0 2 2 2 1 CP2 transcription factor CEP19 PF14933.6 CBY37687.1 - 0.27 11.5 6.5 0.12 12.7 0.4 2.5 3 0 0 3 3 3 0 CEP19-like protein RecQ5 PF06959.11 CBY37687.1 - 10 6.1 16.8 1.1 9.2 11.7 2.0 2 1 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) Ammonium_transp PF00909.21 CBY37688.1 - 2.9e-55 187.6 11.5 3.4e-55 187.4 11.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TCR_zetazeta PF11628.8 CBY37688.1 - 7.8 6.3 7.2 4.7 7.0 2.8 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF4761 PF15958.5 CBY37689.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) DASH_Ask1 PF08655.10 CBY37689.1 - 0.074 12.9 0.6 0.21 11.5 0.6 1.7 1 0 0 1 1 1 0 DASH complex subunit Ask1 PCI PF01399.27 CBY37690.1 - 2.6e-14 53.6 0.6 6.1e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 PCI domain Prenyltransf PF01255.19 CBY37691.1 - 0.091 12.3 0.2 0.19 11.2 0.2 1.6 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Pro_isomerase PF00160.21 CBY37692.1 - 9.4e-22 78.0 0.0 1e-21 77.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tir_receptor_N PF07490.11 CBY37693.1 - 0.028 14.3 0.3 0.97 9.2 0.1 2.9 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) N-terminus Nbl1_Borealin_N PF10444.9 CBY37693.1 - 0.35 10.5 4.1 3 7.5 0.1 4.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Cwf_Cwc_15 PF04889.12 CBY37694.1 - 0.056 13.2 8.0 0.14 11.8 8.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CBY37694.1 - 0.5 8.6 8.1 0.73 8.1 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pro_sub2 PF18513.1 CBY37695.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Prodomain subtilisin 2 OCRE PF17780.1 CBY37695.1 - 0.23 11.5 4.9 0.42 10.7 4.9 1.4 1 0 0 1 1 1 0 OCRE domain FoP_duplication PF13865.6 CBY37696.1 - 1.2 9.8 13.4 1.3 9.6 13.4 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Trypsin PF00089.26 CBY37697.1 - 2e-51 174.9 0.1 2.3e-51 174.7 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY37697.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) LEM PF03020.15 CBY37698.1 - 0.039 13.5 0.3 0.084 12.5 0.3 1.5 1 0 0 1 1 1 0 LEM domain Hep_59 PF07052.11 CBY37698.1 - 6.9 7.5 7.8 1.1 10.0 1.6 2.5 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Methyltransf_16 PF10294.9 CBY37699.1 - 9.5e-33 113.4 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CBY37699.1 - 0.00038 20.3 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY37699.1 - 0.018 14.8 0.1 0.17 11.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBY37699.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DnaJ_C PF01556.18 CBY37700.1 - 1.8e-36 125.5 0.1 2.9e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain Pkinase PF00069.25 CBY37700.1 - 4.5e-20 72.1 0.0 8.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37700.1 - 1e-12 47.9 0.0 2.3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CBY37700.1 - 1.2e-06 29.1 3.1 1.4 9.9 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat HEAT PF02985.22 CBY37700.1 - 0.0055 16.9 0.1 11 6.6 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.6 CBY37700.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.8 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.7 CBY37700.1 - 0.16 12.0 3.4 0.61 10.1 0.1 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PQQ_3 PF13570.6 CBY37700.1 - 0.16 12.5 0.2 7.3 7.2 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain HalOD1 PF18545.1 CBY37700.1 - 0.17 12.1 0.0 0.7 10.2 0.0 1.9 2 0 0 2 2 2 0 Halobacterial output domain 1 ASH PF15780.5 CBY37701.1 - 2.6e-24 85.3 2.0 0.0067 16.6 0.0 11.9 10 2 1 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY37701.1 - 8.1e-19 67.5 10.4 0.0036 17.1 0.1 11.3 12 0 0 12 12 12 4 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY37701.1 - 6.2e-14 51.8 10.6 0.062 13.3 0.0 11.5 13 1 0 13 13 13 2 Protein of unknown function (DUF1573) Hydin_ADK PF17213.3 CBY37701.1 - 2.9e-12 47.3 0.5 5.6e-12 46.4 0.5 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain PapD-like PF14874.6 CBY37701.1 - 5.5e-11 42.5 0.2 1.9 8.7 0.0 9.1 10 0 0 10 10 10 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 CBY37701.1 - 0.0019 18.4 7.4 8.1 6.8 0.1 7.0 9 0 0 9 9 9 1 Transmembrane protein 131-like AAA_17 PF13207.6 CBY37701.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CBY37701.1 - 0.029 14.5 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase SoxY PF13501.6 CBY37701.1 - 0.13 12.5 0.1 0.53 10.5 0.1 2.1 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY AAA_28 PF13521.6 CBY37701.1 - 0.15 12.3 0.4 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF4706 PF15797.5 CBY37702.1 - 0.16 12.5 5.7 0.2 12.2 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) ERM PF00769.19 CBY37702.1 - 0.66 9.7 24.7 0.84 9.4 24.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Ebola_NP PF05505.12 CBY37702.1 - 2.1 6.6 8.1 2.4 6.4 8.1 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Metal_resist PF13801.6 CBY37702.1 - 4.6 7.5 9.6 9.1 6.5 8.7 1.8 1 1 1 2 2 2 0 Heavy-metal resistance Nup88 PF10168.9 CBY37702.1 - 9.7 3.9 14.4 11 3.7 14.4 1.0 1 0 0 1 1 1 0 Nuclear pore component Prominin PF05478.11 CBY37703.1 - 0.0036 15.3 3.5 0.0064 14.5 3.5 1.3 1 0 0 1 1 1 1 Prominin SYCP2_SLD PF18584.1 CBY37703.1 - 0.085 13.1 1.0 0.37 11.0 0.4 2.2 1 1 1 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain GIT1_C PF12205.8 CBY37703.1 - 0.11 12.5 7.6 0.34 11.0 7.6 1.8 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term LRR_8 PF13855.6 CBY37705.1 - 0.071 12.9 0.5 1.7 8.5 0.0 2.8 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBY37705.1 - 0.66 10.5 7.5 0.76 10.3 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) UBA PF00627.31 CBY37707.1 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 CBY37707.1 - 0.0089 15.8 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Merozoite_SPAM PF07133.11 CBY37707.1 - 0.16 11.9 13.7 0.28 11.2 13.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MS_channel PF00924.18 CBY37707.1 - 0.56 9.7 2.1 0.66 9.5 1.2 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel Presenilin PF01080.17 CBY37708.1 - 0.78 8.4 6.2 0.78 8.4 6.2 1.1 1 0 0 1 1 1 0 Presenilin Ion_trans PF00520.31 CBY37710.1 - 2.3e-27 95.8 16.3 3e-27 95.4 16.3 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY37710.1 - 1.1e-09 38.1 2.4 1.1e-09 38.1 2.4 2.4 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 CBY37710.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PDZ PF00595.24 CBY37713.1 - 5.3e-21 74.8 0.0 6.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY37713.1 - 1.9e-16 59.6 0.1 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY37713.1 - 3.5e-05 24.1 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY37713.1 - 0.01 15.8 0.0 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain p450 PF00067.22 CBY37714.1 - 1.2e-59 202.3 0.0 1.5e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ALMT PF11744.8 CBY37715.1 - 0.22 10.3 6.1 0.23 10.3 6.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter EGF_CA PF07645.15 CBY37716.1 - 7.9e-120 390.9 321.3 1.5e-10 41.1 8.0 23.4 22 2 2 24 24 24 20 Calcium-binding EGF domain EGF_3 PF12947.7 CBY37716.1 - 1.6e-73 242.6 273.5 1.9e-08 34.3 6.7 23.5 21 3 3 24 24 24 21 EGF domain cEGF PF12662.7 CBY37716.1 - 8.3e-43 143.9 209.9 4.3e-06 26.5 3.9 22.6 21 1 0 21 21 21 16 Complement Clr-like EGF-like EGF PF00008.27 CBY37716.1 - 3.6e-29 100.7 268.5 9.7e-05 22.6 4.5 23.2 22 0 0 22 22 22 17 EGF-like domain FXa_inhibition PF14670.6 CBY37716.1 - 8.9e-18 64.3 274.5 0.0019 18.4 5.0 22.8 18 4 5 23 23 23 15 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY37716.1 - 1e-10 41.9 232.9 0.0002 21.9 2.0 22.7 21 0 0 21 21 21 13 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY37716.1 - 0.0031 17.5 2.5 0.0031 17.5 2.5 21.5 21 0 0 21 21 21 12 MSP1 EGF domain 1 DUF4158 PF13700.6 CBY37717.1 - 0.078 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) HMG_box PF00505.19 CBY37718.1 - 6.2e-24 84.2 4.0 6.2e-24 84.2 4.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY37718.1 - 5.1e-09 36.6 2.1 5.1e-09 36.6 2.1 2.0 2 0 0 2 2 2 1 HMG-box domain Astacin PF01400.24 CBY37720.1 - 4.1e-26 91.8 0.0 6.8e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY37720.1 - 1.2e-06 28.6 7.5 1.2e-06 28.6 7.5 4.9 5 0 0 5 5 5 1 Low-density lipoprotein receptor domain class A Troponin PF00992.20 CBY37721.1 - 9.5e-35 119.8 17.5 1.2e-34 119.5 17.5 1.0 1 0 0 1 1 1 1 Troponin LXG PF04740.12 CBY37721.1 - 0.036 13.8 1.7 0.052 13.2 1.4 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily SIN1_PH PF16979.5 CBY37721.1 - 0.092 13.0 1.5 0.15 12.3 1.5 1.6 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology SLATT_fungal PF18142.1 CBY37721.1 - 0.16 12.0 0.6 0.29 11.1 0.6 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain GLTSCR1 PF15249.6 CBY37721.1 - 0.16 12.4 4.1 0.32 11.4 4.0 1.7 1 1 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein eIF3_N PF09440.10 CBY37721.1 - 0.5 10.8 6.8 2.2 8.7 5.2 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain DivIC PF04977.15 CBY37721.1 - 0.58 10.0 8.1 0.74 9.6 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CBY37721.1 - 1.4 9.4 9.0 0.077 13.4 2.2 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MRPL52 PF18699.1 CBY37721.1 - 8.6 6.6 12.5 9.3 6.5 1.6 2.4 2 1 0 2 2 2 0 Mitoribosomal protein mL52 Annexin PF00191.20 CBY37722.1 - 1.5e-54 182.0 0.4 3.8e-15 55.7 0.0 4.1 4 0 0 4 4 4 4 Annexin Ion_trans PF00520.31 CBY37723.1 - 5e-169 559.7 90.4 9.5e-61 205.1 24.0 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CBY37723.1 - 1.8e-15 56.4 0.1 4.1e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 CBY37723.1 - 2.4e-12 46.9 0.1 6.4e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 CBY37723.1 - 7.2e-11 41.4 66.4 2.8e-08 32.9 5.3 7.3 5 3 2 8 8 8 5 Polycystin cation channel zf-RING_2 PF13639.6 CBY37725.1 - 2.5e-07 30.9 12.5 2.5e-07 30.9 12.5 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY37725.1 - 5.2e-06 26.2 24.0 0.00023 21.0 13.6 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY37725.1 - 6e-06 26.0 10.4 6e-06 26.0 10.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY37725.1 - 5.1e-05 23.0 15.7 0.00056 19.7 12.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY37725.1 - 5.1e-05 23.2 11.6 0.0011 18.9 5.3 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY37725.1 - 7.9e-05 22.5 12.7 7.9e-05 22.5 12.7 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY37725.1 - 0.017 14.9 11.2 0.017 14.9 11.2 3.6 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CBY37725.1 - 0.04 13.9 11.7 0.035 14.0 9.6 2.0 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) DUF4208 PF13907.6 CBY37725.1 - 0.074 13.5 0.2 0.17 12.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) DUF2256 PF10013.9 CBY37725.1 - 0.077 13.1 0.3 0.077 13.1 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2120 PF09893.9 CBY37725.1 - 0.11 12.6 0.3 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) RIH_assoc PF08454.11 CBY37725.1 - 0.29 11.0 3.1 5.2 7.0 3.1 2.6 1 1 0 1 1 1 0 RyR and IP3R Homology associated Rtf2 PF04641.12 CBY37725.1 - 0.39 10.0 7.9 0.16 11.3 5.0 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 CBY37725.1 - 0.7 9.7 10.2 0.24 11.2 6.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY37725.1 - 5.2 7.3 19.6 18 5.6 10.2 3.9 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBY37725.1 - 7.9 6.4 21.6 0.064 13.1 9.5 3.2 3 1 1 4 4 3 0 Prokaryotic RING finger family 4 FapA PF03961.13 CBY37727.1 - 0.026 13.2 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Flu_C_NS2 PF03555.14 CBY37727.1 - 0.11 12.6 0.3 0.76 10.0 0.1 2.3 3 0 0 3 3 3 0 Influenza C non-structural protein (NS2) zf-RING_2 PF13639.6 CBY37728.1 - 1.5e-07 31.7 11.9 2.4e-07 31.0 11.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY37728.1 - 1.1e-06 28.3 10.3 1.8e-06 27.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY37728.1 - 6.4e-06 26.0 12.4 9.5e-06 25.5 12.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY37728.1 - 1.1e-05 25.3 4.1 0.00049 20.1 6.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY37728.1 - 1.3e-05 25.0 10.5 3.3e-05 23.7 10.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY37728.1 - 5.6e-05 22.9 9.4 0.00078 19.3 9.0 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBY37728.1 - 0.00015 21.6 11.6 0.00024 20.9 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBY37728.1 - 0.0002 21.4 7.2 0.00023 21.1 7.2 1.1 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 CBY37728.1 - 0.0026 17.5 11.0 0.0044 16.8 11.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBY37728.1 - 0.0058 16.4 3.1 0.0058 16.4 3.1 2.4 2 1 0 2 2 2 1 RING-like zinc finger Rtf2 PF04641.12 CBY37728.1 - 0.034 13.5 3.9 0.039 13.3 3.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Prefoldin_2 PF01920.20 CBY37728.1 - 0.039 13.9 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit zf-C3HC4_4 PF15227.6 CBY37728.1 - 0.089 13.0 9.7 4.6 7.5 10.7 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2256 PF10013.9 CBY37728.1 - 0.93 9.7 10.1 0.15 12.2 2.2 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) IBR PF01485.21 CBY37728.1 - 1.7 9.0 12.5 0.88 9.8 6.0 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CBY37728.1 - 1.9 8.7 12.6 1.8 8.8 6.0 2.2 1 1 1 2 2 2 0 FYVE zinc finger RHD_dimer PF16179.5 CBY37729.1 - 2.8e-19 69.0 0.0 1e-18 67.2 0.0 2.0 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 CBY37729.1 - 1.3e-14 54.5 0.8 2.7e-14 53.5 0.8 1.6 1 0 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 CBY37729.1 - 0.002 18.2 0.2 0.021 14.9 0.0 2.9 2 1 1 3 3 3 1 IPT/TIG domain DUF1505 PF07403.11 CBY37729.1 - 0.51 10.5 5.5 0.58 10.4 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1505) SET PF00856.28 CBY37730.1 - 3e-08 34.2 0.0 5.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 SET domain PRESAN PF09687.10 CBY37730.1 - 0.02 15.5 1.1 0.26 11.9 0.1 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal AF0941-like PF14591.6 CBY37730.1 - 0.05 14.2 0.1 0.05 14.2 0.1 2.1 2 0 0 2 2 2 0 AF0941-like Actin PF00022.19 CBY37731.1 - 5.7e-67 226.1 0.0 8.8e-66 222.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBY37731.1 - 0.003 16.4 0.0 0.48 9.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Imm43 PF15570.6 CBY37731.1 - 0.081 12.9 2.8 1.9 8.5 1.3 2.4 1 1 1 2 2 2 0 Immunity protein 43 Flot PF15975.5 CBY37732.1 - 6.6e-12 45.7 13.5 8.2e-12 45.4 10.9 2.1 1 1 1 2 2 2 2 Flotillin CDI PF02234.19 CBY37734.1 - 0.064 13.5 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Acatn PF13000.7 CBY37735.1 - 5.1e-31 107.8 17.2 2e-25 89.3 10.1 2.9 1 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 PA26 PF04636.13 CBY37736.1 - 3e-77 260.4 8.6 4.3e-77 259.9 8.6 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) BIR PF00653.21 CBY37737.1 - 1.2e-36 125.2 5.8 5.6e-18 65.4 0.9 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CBY37737.1 - 1.2e-06 28.6 0.5 0.042 13.9 0.0 2.4 1 1 1 2 2 2 2 C3HC zinc finger-like MFS_1 PF07690.16 CBY37738.1 - 1.4e-07 30.8 5.2 1.4e-07 30.8 5.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Deltaretro_Tax PF05599.11 CBY37738.1 - 0.057 13.9 0.0 0.09 13.3 0.0 1.3 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Sulfotransfer_1 PF00685.27 CBY37741.1 - 1.2e-16 61.0 0.0 2.7e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY37741.1 - 2.6e-11 44.3 0.0 1.8e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family Ly49 PF08391.10 CBY37741.1 - 3.5 8.0 5.1 81 3.6 0.0 3.1 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Neur_chan_LBD PF02931.23 CBY37742.1 - 2.2e-26 92.7 1.7 2.8e-26 92.3 1.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain FtsJ PF01728.19 CBY37744.1 - 1.1e-09 38.7 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mucin2_WxxW PF13330.6 CBY37745.1 - 1.8e-154 503.0 106.9 1.2e-14 54.8 1.7 13.9 14 0 0 14 14 14 13 Mucin-2 protein WxxW repeating region RepL PF05732.11 CBY37746.1 - 0.02 14.3 2.8 0.081 12.4 0.7 2.2 1 1 1 2 2 2 0 Firmicute plasmid replication protein (RepL) 7tm_1 PF00001.21 CBY37747.1 - 1.6e-45 155.5 16.5 2.2e-45 155.0 16.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_4 PF13853.6 CBY37747.1 - 2.7e-06 27.3 7.8 3.8e-06 26.9 7.8 1.2 1 0 0 1 1 1 1 Olfactory receptor TerC PF03741.16 CBY37747.1 - 7.7 6.2 8.5 10 5.8 3.3 2.8 2 1 0 2 2 2 0 Integral membrane protein TerC family PWWP PF00855.17 CBY37748.1 - 2.1e-14 53.7 0.0 4.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 PWWP domain DUF240 PF03086.14 CBY37750.1 - 0.098 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF240) Ribosomal_S21e PF01249.18 CBY37751.1 - 7.5e-38 128.5 0.0 8.2e-38 128.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NAD_binding_1 PF00175.21 CBY37752.1 - 6.4e-14 52.5 0.0 9.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBY37752.1 - 1e-10 42.0 0.0 6.1e-08 32.9 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Rhomboid PF01694.22 CBY37754.1 - 3.2e-10 40.2 19.3 7.4e-10 39.0 15.1 2.7 2 1 0 2 2 2 1 Rhomboid family HSP70 PF00012.20 CBY37755.1 - 1.5e-136 456.0 8.8 9.2e-135 450.1 8.8 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBY37755.1 - 6.4e-09 35.1 0.0 1.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein DASH_Spc19 PF08287.11 CBY37755.1 - 0.69 9.8 3.9 2.7 7.9 3.9 2.0 1 0 0 1 1 1 0 Spc19 CPSF73-100_C PF11718.8 CBY37756.1 - 4.5e-44 150.6 1.5 7.4e-44 149.9 1.5 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CBY37756.1 - 1e-32 112.7 0.0 2.9e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 CBY37756.1 - 2.8e-21 75.2 0.2 5.9e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CBY37756.1 - 5.3e-16 59.2 1.2 9.3e-16 58.4 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CBY37756.1 - 1.6e-15 57.1 0.0 6.8e-15 55.0 0.0 2.1 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CBY37756.1 - 2.3e-07 30.5 1.3 4.6e-07 29.6 0.2 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBY37756.1 - 0.0051 16.7 0.4 0.51 10.2 0.2 3.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Glyco_transf_28 PF03033.20 CBY37756.1 - 0.092 12.8 0.1 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain EABR PF12180.8 CBY37757.1 - 1e-05 25.0 1.3 2e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 TSG101 and ALIX binding domain of CEP55 FUSC PF04632.12 CBY37757.1 - 2.7 6.4 4.4 3.6 6.0 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPT16 PF08644.11 CBY37757.1 - 2.9 8.1 12.3 25 5.0 12.3 2.4 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) FliD_N PF02465.18 CBY37757.1 - 5.1 7.8 12.1 0.82 10.4 5.9 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF148 PF02520.17 CBY37757.1 - 8.1 6.6 18.0 0.49 10.5 7.0 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 DNA_RNApol_7kD PF03604.13 CBY37758.1 - 7.5e-16 57.5 7.0 9.5e-16 57.2 7.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_13 PF09855.9 CBY37758.1 - 0.03 14.5 0.1 0.03 14.5 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GFA PF04828.14 CBY37758.1 - 0.068 13.5 0.4 4.2 7.8 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Spore_III_AF PF09581.10 CBY37759.1 - 9.8 6.2 10.0 9.2 6.2 0.3 3.0 3 0 0 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) DUF4166 PF13761.6 CBY37760.1 - 0.17 11.6 0.0 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) Cadherin_C_2 PF16492.5 CBY37760.1 - 0.27 12.0 1.6 1.8 9.4 1.6 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 CBY37760.1 - 0.34 10.7 2.8 0.59 9.9 2.8 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kinocilin PF15033.6 CBY37760.1 - 0.51 10.0 3.1 0.76 9.4 2.8 1.6 1 1 0 1 1 1 0 Kinocilin protein DUF4519 PF15012.6 CBY37760.1 - 5.7 7.2 4.6 4.1 7.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) WD40 PF00400.32 CBY37762.1 - 1.9e-11 44.3 5.8 0.0032 18.3 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PCI PF01399.27 CBY37763.1 - 3.6e-19 69.2 1.5 3.6e-19 69.2 1.5 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CBY37763.1 - 0.041 14.0 4.1 0.077 13.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY37763.1 - 0.3 11.0 1.3 0.78 9.7 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 CBY37764.1 - 1.8e-44 152.3 0.0 2.9e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY37764.1 - 8.9e-05 22.2 0.4 0.00045 19.9 0.4 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C eIF3_subunit PF08597.10 CBY37764.1 - 0.34 10.8 10.3 0.59 10.0 10.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PH PF00169.29 CBY37765.1 - 3.4e-07 30.7 0.2 6.9e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 PH domain RA PF00788.23 CBY37765.1 - 4.1e-07 30.6 0.1 8.5e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain zf-H2C2_2 PF13465.6 CBY37766.1 - 2.9e-19 68.5 24.6 9.8e-08 32.1 2.9 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY37766.1 - 7.9e-13 48.1 25.1 1.9e-06 28.0 3.5 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37766.1 - 3.3e-12 46.1 22.0 0.00026 21.5 2.2 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY37766.1 - 5.4e-08 33.0 9.7 1.3e-06 28.6 3.9 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CBY37766.1 - 1.4e-06 28.2 14.4 0.00067 19.6 2.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY37766.1 - 7.8e-06 26.0 8.9 0.45 10.9 0.6 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CBY37766.1 - 0.0017 18.3 3.1 0.0017 18.3 3.1 2.8 2 1 1 3 3 3 1 BED zinc finger Prok-RING_1 PF14446.6 CBY37766.1 - 0.0021 18.0 4.5 1.7 8.6 0.1 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 Zn-C2H2_12 PF18112.1 CBY37766.1 - 0.0023 18.4 7.2 1.5 9.4 0.5 3.6 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 CBY37766.1 - 0.0031 17.3 6.9 0.35 10.7 0.1 3.3 1 1 2 3 3 3 2 GAGA factor zf-CHCC PF10276.9 CBY37766.1 - 0.0042 17.1 2.4 1.9 8.6 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger domain zf-met PF12874.7 CBY37766.1 - 0.011 16.2 12.0 1.3 9.5 2.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CBY37766.1 - 0.018 15.7 8.0 0.78 10.4 1.6 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 CBY37766.1 - 0.023 15.0 1.5 6.5 7.1 0.1 2.6 1 1 1 2 2 2 0 BolA-like protein Zf_RING PF16744.5 CBY37766.1 - 0.023 14.8 6.6 0.98 9.6 1.6 3.0 1 1 2 3 3 3 0 KIAA1045 RING finger zinc_ribbon_15 PF17032.5 CBY37766.1 - 0.03 15.0 5.9 2 9.3 4.4 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_2 PF12756.7 CBY37766.1 - 0.032 14.6 13.3 0.35 11.2 0.9 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY37766.1 - 0.23 11.3 5.2 6.9 6.5 0.0 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type Elf1 PF05129.13 CBY37766.1 - 0.23 11.5 7.8 0.95 9.6 3.4 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HNH_5 PF14279.6 CBY37766.1 - 0.34 10.8 4.8 8.1 6.4 0.4 3.1 2 1 0 2 2 2 0 HNH endonuclease FYVE PF01363.21 CBY37766.1 - 0.34 11.1 11.9 1.3 9.2 6.2 2.6 1 1 2 3 3 3 0 FYVE zinc finger zf-AN1 PF01428.16 CBY37766.1 - 0.35 11.1 12.0 5.5 7.2 4.8 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger Cys_rich_CPXG PF14255.6 CBY37766.1 - 0.54 10.2 2.7 1.3 9.0 0.6 2.5 2 1 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2_9 PF16293.5 CBY37766.1 - 0.57 10.1 4.0 3.2 7.7 0.1 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 CBY37766.1 - 0.7 9.9 8.2 2.6 8.0 1.0 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger FYDLN_acid PF09538.10 CBY37766.1 - 0.82 10.4 3.1 29 5.4 3.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 CBY37766.1 - 1.3 9.2 8.1 13 6.0 3.5 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 CBY37766.1 - 1.7 8.5 25.3 0.36 10.6 1.7 5.0 4 2 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 CBY37766.1 - 1.9 8.5 13.0 1 9.3 3.5 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 CBY37766.1 - 3.4 8.0 8.8 0.2 12.0 1.2 2.5 2 1 0 2 2 2 0 zinc-ribbon zf_ZIC PF18366.1 CBY37766.1 - 5.9 7.1 8.8 0.31 11.2 0.5 2.6 2 1 1 3 3 3 0 Zic proteins zinc finger domain Sulfotransfer_3 PF13469.6 CBY37767.1 - 3e-15 57.2 0.0 7.3e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY37767.1 - 6.1e-13 48.9 0.7 4.1e-12 46.1 0.7 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_79n PF03662.14 CBY37768.1 - 5e-66 222.8 0.0 6.4e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain CO_dh PF02552.16 CBY37769.1 - 0.11 12.3 0.5 0.13 12.0 0.5 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit CIDR1_gamma PF18562.1 CBY37769.1 - 1.1 9.5 6.5 2.3 8.4 6.5 1.7 1 1 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma Collagen PF01391.18 CBY37770.1 - 1.2e-18 66.6 85.1 2.1e-08 33.8 31.9 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 CBY37770.1 - 0.00014 22.4 0.1 8 7.2 0.0 3.4 3 0 0 3 3 3 3 von Willebrand factor type A domain DUF3439 PF11921.8 CBY37770.1 - 1.5 8.8 8.4 3.1 7.8 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UPF0016 PF01169.19 CBY37772.1 - 7.5e-38 128.7 19.9 1.7e-19 69.9 8.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF373 PF04123.13 CBY37772.1 - 0.32 10.4 3.0 1.2 8.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) zf-C3HC4_3 PF13920.6 CBY37773.1 - 0.00013 21.7 14.6 0.00013 21.7 14.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY37773.1 - 0.0018 18.4 13.6 0.0018 18.4 13.6 2.6 2 1 1 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 CBY37773.1 - 0.015 15.2 17.6 0.015 15.2 17.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ureidogly_lyase PF04115.12 CBY37773.1 - 0.36 10.6 5.5 2.2 8.0 5.5 2.1 1 1 0 1 1 1 0 Ureidoglycolate lyase zf-RING_6 PF14835.6 CBY37773.1 - 0.56 10.1 6.3 1.3 8.9 6.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ERM PF00769.19 CBY37773.1 - 0.61 9.9 45.5 2.3 8.0 15.5 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family Prok-RING_4 PF14447.6 CBY37773.1 - 1.3 8.9 19.7 0.16 11.8 13.0 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY37773.1 - 3.5 7.5 20.0 10 6.0 12.3 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf_UBZ PF18439.1 CBY37773.1 - 6.5 6.4 16.3 0.35 10.5 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CALCOCO1 PF07888.11 CBY37774.1 - 0.00033 19.7 21.6 0.00048 19.1 21.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Prok-RING_4 PF14447.6 CBY37774.1 - 0.00068 19.4 5.5 0.00068 19.4 5.5 2.8 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY37774.1 - 0.0019 18.1 6.9 0.0019 18.1 6.9 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RAG1 PF10426.9 CBY37774.1 - 0.0033 17.5 0.1 0.0033 17.5 0.1 1.9 2 0 0 2 2 2 1 Recombination-activating protein 1 zinc-finger domain zinc_ribbon_15 PF17032.5 CBY37774.1 - 0.18 12.6 18.4 0.29 11.9 9.5 2.9 2 0 0 2 2 2 0 zinc-ribbon family Spc7 PF08317.11 CBY37774.1 - 0.67 8.8 31.5 0.35 9.7 0.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-ACC PF17848.1 CBY37774.1 - 3.2 7.9 12.5 6.2 7.0 0.1 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Jnk-SapK_ap_N PF09744.9 CBY37774.1 - 6.5 7.0 30.8 3.6 7.8 18.1 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Galactosyl_T PF01762.21 CBY37775.1 - 3.6e-20 72.6 0.1 4.2e-19 69.1 0.0 2.6 3 0 0 3 3 3 1 Galactosyltransferase SAUGI PF06106.11 CBY37775.1 - 0.037 14.5 1.0 0.14 12.6 0.1 2.4 3 0 0 3 3 3 0 S. aureus uracil DNA glycosylase inhibitor Aminotran_3 PF00202.21 CBY37776.1 - 5.8e-105 351.3 0.0 7e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.12 CBY37776.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain Peptidase_M20 PF01546.28 CBY37777.1 - 9.2e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY37777.1 - 7.1e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Antibiotic_NAT PF02522.14 CBY37777.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Peptidase_M28 PF04389.17 CBY37777.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Fur_reg_FbpB PF13040.6 CBY37777.1 - 0.14 11.7 0.2 0.35 10.5 0.2 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B zf-RING_2 PF13639.6 CBY37778.1 - 6.1e-09 36.1 8.7 1e-08 35.3 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY37778.1 - 1.9e-08 34.0 5.9 4.9e-08 32.7 6.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY37778.1 - 1.3e-07 31.5 2.6 6.7e-07 29.2 2.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY37778.1 - 9e-07 28.8 9.5 1.5e-06 28.1 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY37778.1 - 5.6e-06 26.1 8.2 1.1e-05 25.2 8.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY37778.1 - 2.3e-05 23.9 1.5 2.7e-05 23.7 1.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CBY37778.1 - 3.5e-05 23.5 9.7 5.3e-05 22.9 9.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CBY37778.1 - 8.3e-05 22.2 2.8 8.3e-05 22.2 2.8 1.8 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBY37778.1 - 0.00027 20.7 6.7 0.0008 19.2 6.8 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 CBY37778.1 - 0.00059 19.9 8.0 0.0061 16.7 8.0 2.0 1 1 0 1 1 1 1 FYVE zinc finger DUF1272 PF06906.11 CBY37778.1 - 0.0013 18.7 8.3 0.0019 18.3 8.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 CBY37778.1 - 0.0042 17.2 11.5 0.028 14.6 9.8 2.8 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING DZR PF12773.7 CBY37778.1 - 0.0073 16.3 9.3 0.0077 16.2 4.2 2.2 1 1 1 2 2 2 1 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 CBY37778.1 - 0.2 11.7 9.3 3 8.0 0.1 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-HYPF PF07503.12 CBY37778.1 - 0.75 9.6 0.2 0.75 9.6 0.2 3.5 4 0 0 4 4 4 0 HypF finger zinc_ribbon_4 PF13717.6 CBY37778.1 - 1.1 9.2 9.8 2.5 8.1 0.4 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zf-MYND PF01753.18 CBY37778.1 - 1.5 9.0 9.0 7.1 6.8 0.7 2.2 2 0 0 2 2 2 0 MYND finger IBR PF01485.21 CBY37778.1 - 2.5 8.4 11.3 54 4.1 11.2 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-rbx1 PF12678.7 CBY37778.1 - 3.4 8.0 9.3 17 5.8 9.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase PF00069.25 CBY37779.1 - 3e-53 180.9 0.0 1.6e-37 129.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37779.1 - 2.4e-30 105.7 0.0 6.2e-23 81.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBY37779.1 - 0.066 13.1 0.2 0.37 10.7 0.2 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family DsbG_N PF18257.1 CBY37780.1 - 0.076 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Disulfide isomerase DsbG N-terminal Insulin PF00049.18 CBY37781.1 - 0.012 16.6 9.2 0.026 15.5 0.3 2.8 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family Histone PF00125.24 CBY37782.1 - 1.4e-21 77.2 0.6 1.7e-21 76.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY37782.1 - 5.4e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY37782.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY37782.1 - 0.00041 20.4 0.3 0.00044 20.3 0.3 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY37782.1 - 0.033 14.4 0.7 0.087 13.1 0.7 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY37783.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY37783.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY37783.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBY37786.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY37786.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY37786.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY37786.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY37786.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY37786.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY37786.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY37786.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CBY37787.1 - 6.8e-54 181.7 2.3 7.6e-54 181.6 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY37787.1 - 8.4e-05 22.6 0.3 0.00015 21.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY37787.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY37787.1 - 0.00042 20.6 0.0 0.00064 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY37787.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBY37787.1 - 0.11 12.6 0.1 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RNB PF00773.19 CBY37789.1 - 5.4e-100 334.9 0.0 8.1e-100 334.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBY37789.1 - 6.3e-18 64.6 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CBY37789.1 - 3.1e-14 52.9 0.0 5.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CBY37789.1 - 2.2e-13 49.9 0.6 2.2e-13 49.9 0.6 1.9 2 0 0 2 2 2 1 S1 domain PIN_4 PF13638.6 CBY37789.1 - 4.5e-09 36.7 0.0 1.7e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CBY37789.1 - 1.1e-07 31.9 0.1 1.2e-05 25.4 0.1 2.9 2 0 0 2 2 2 1 Cold shock domain Dis3l2_C_term PF17877.1 CBY37789.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 CBY37789.1 - 0.018 14.7 0.0 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain Amidohydro_2 PF04909.14 CBY37791.1 - 2.9e-57 194.7 0.4 3.2e-57 194.5 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase HemY_N PF07219.13 CBY37792.1 - 0.069 13.3 0.1 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 HemY protein N-terminus NPCC PF08058.11 CBY37792.1 - 3.1 7.9 5.2 8.7 6.4 5.2 1.7 1 0 0 1 1 1 0 Nuclear pore complex component FG-GAP PF01839.23 CBY37793.1 - 3.2e-07 30.3 14.7 9.7e-07 28.8 1.9 3.6 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.6 CBY37793.1 - 4.3e-06 27.2 4.0 0.00014 22.4 0.5 2.2 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 CBY37793.1 - 0.0002 21.5 7.6 0.13 12.5 0.4 5.3 5 1 0 5 5 5 1 FG-GAP repeat MT PF12777.7 CBY37794.1 - 1.4e-10 40.8 0.3 8.5e-10 38.2 0.2 2.2 1 1 1 2 2 2 1 Microtubule-binding stalk of dynein motor IL2 PF00715.17 CBY37794.1 - 0.018 15.0 4.0 0.11 12.5 1.9 2.9 2 0 0 2 2 2 0 Interleukin 2 DUF4600 PF15372.6 CBY37794.1 - 0.096 13.1 9.6 0.038 14.4 4.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF5600 PF18150.1 CBY37794.1 - 0.15 12.6 2.0 0.46 11.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5600) DUF892 PF05974.12 CBY37794.1 - 0.27 11.2 2.5 0.51 10.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) BLOC1_2 PF10046.9 CBY37794.1 - 6.3 7.2 12.0 5.2 7.5 0.7 4.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynein_AAA_lid PF17852.1 CBY37795.1 - 0.07 13.2 0.7 0.43 10.7 0.0 2.8 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain Csm2_III-A PF03750.13 CBY37795.1 - 0.13 13.1 11.2 3.8 8.4 1.2 5.4 5 0 0 5 5 5 0 Csm2 Type III-A UPF0184 PF03670.13 CBY37795.1 - 0.29 11.5 7.1 6.5 7.2 3.1 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) FliD_N PF02465.18 CBY37795.1 - 8.4 7.2 10.4 0.49 11.1 1.5 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Piwi PF02171.17 CBY37796.1 - 1.3e-55 188.7 0.0 1.9e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY37796.1 - 2.2e-08 34.8 0.0 4.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY37796.1 - 3.1e-05 23.5 0.0 8.6e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY37796.1 - 0.0041 17.4 0.1 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain Trypsin PF00089.26 CBY37797.1 - 1.6e-43 149.1 0.0 2.3e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Kringle PF00051.18 CBY37797.1 - 5e-08 33.1 1.3 5e-08 33.1 1.3 2.1 2 1 0 2 2 2 1 Kringle domain DUF1986 PF09342.11 CBY37797.1 - 0.0077 16.6 0.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) NKWYS PF10364.9 CBY37797.1 - 0.15 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Kringle PF00051.18 CBY37798.1 - 3.1e-10 40.2 6.5 1e-09 38.6 6.5 1.7 1 1 0 1 1 1 1 Kringle domain Aa_trans PF01490.18 CBY37799.1 - 3.6e-26 91.8 30.8 7e-18 64.5 3.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY37799.1 - 3.7e-06 26.2 4.1 3.7e-06 26.2 4.1 2.9 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family DUF4131 PF13567.6 CBY37799.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) ATG27 PF09451.10 CBY37799.1 - 4.2 7.2 4.7 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Autophagy-related protein 27 WD40 PF00400.32 CBY37800.1 - 5.3e-10 39.7 1.5 0.0041 17.9 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat YqgF PF14639.6 CBY37800.1 - 0.016 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 STATa_Ig PF18214.1 CBY37800.1 - 0.1 12.6 0.9 0.19 11.7 0.9 1.4 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain zf-C3H1 PF10650.9 CBY37801.1 - 0.022 14.5 0.6 0.058 13.1 0.6 1.8 1 0 0 1 1 1 0 Putative zinc-finger domain Ras PF00071.22 CBY37802.1 - 4e-60 202.1 0.0 4.7e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY37802.1 - 1.7e-32 112.1 0.2 3.5e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY37802.1 - 4.1e-15 55.7 0.0 5.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY37802.1 - 6.3e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY37802.1 - 0.00019 21.1 0.0 0.0041 16.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY37802.1 - 0.00032 20.1 0.0 0.00048 19.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBY37802.1 - 0.00047 20.1 0.0 1 9.2 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CBY37802.1 - 0.041 14.2 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CBY37802.1 - 0.041 13.6 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain TetR_C_16 PF17920.1 CBY37802.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 CBY37802.1 - 0.076 13.3 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CBY37802.1 - 0.077 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin DAP3 PF10236.9 CBY37802.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 CBY37802.1 - 0.13 12.7 0.0 2.1 8.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Steroid_dh PF02544.16 CBY37803.1 - 4.7e-29 101.3 4.1 9.4e-29 100.3 4.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 CBY37803.1 - 6.9e-05 22.5 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CBY37803.1 - 0.058 14.0 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PH PF00169.29 CBY37804.1 - 7.7e-06 26.4 0.1 2e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 PH domain DUF5377 PF17347.2 CBY37804.1 - 0.098 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5377) Baculo_PEP_C PF04513.12 CBY37804.1 - 0.4 10.7 2.8 0.79 9.8 0.0 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TTL PF03133.15 CBY37805.1 - 6.1e-87 291.5 0.0 6.1e-87 291.5 0.0 2.0 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY37805.1 - 3.2e-06 26.6 0.0 0.0032 16.8 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY37805.1 - 0.015 14.6 0.0 0.4 9.9 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Kelch_5 PF13854.6 CBY37806.1 - 5.9e-24 83.6 0.2 0.00047 20.1 0.0 6.6 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBY37806.1 - 2.3e-18 66.0 0.1 5e-05 23.5 0.0 5.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY37806.1 - 2.9e-18 65.6 0.1 0.00023 21.1 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY37806.1 - 2.1e-13 50.0 0.0 0.12 12.7 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CBY37806.1 - 7.3e-13 47.9 1.7 0.0011 18.4 0.0 5.6 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBY37806.1 - 1.7e-11 43.6 2.8 0.78 9.8 0.0 6.3 6 0 0 6 6 6 4 Kelch motif fn3 PF00041.21 CBY37806.1 - 9.8e-09 35.5 1.7 0.0086 16.4 0.0 4.1 4 0 0 4 4 4 2 Fibronectin type III domain DUF3203 PF11462.8 CBY37806.1 - 0.15 12.2 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3203) Pur_ac_phosph_N PF16656.5 CBY37806.1 - 0.61 10.7 4.4 13 6.5 4.4 2.9 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain ALG11_N PF15924.5 CBY37807.1 - 2.7e-87 292.2 0.5 4.8e-87 291.4 0.3 1.5 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CBY37807.1 - 1.1e-25 90.2 0.0 1.7e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY37807.1 - 2.1e-10 41.1 0.0 9.5e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY37807.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 HEAT_EZ PF13513.6 CBY37808.1 - 4.6e-17 62.1 0.5 2.2e-08 34.4 0.0 6.4 7 0 0 7 7 6 2 HEAT-like repeat HEAT PF02985.22 CBY37808.1 - 6.4e-13 47.8 1.8 0.00022 21.2 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat IBN_N PF03810.19 CBY37808.1 - 3.2e-09 36.6 7.6 8.4e-09 35.2 1.6 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CBY37808.1 - 2.9e-06 27.6 3.8 0.0082 16.5 0.0 5.2 5 2 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CBY37808.1 - 5.2e-06 27.0 1.1 0.78 10.4 0.6 4.5 4 1 1 5 5 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 CBY37808.1 - 8.2e-06 25.7 2.1 4.7 7.4 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CBY37808.1 - 1e-05 25.6 3.0 0.0001 22.4 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 CBY37808.1 - 0.00012 21.9 3.1 0.0081 16.1 0.0 4.2 4 1 0 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.8 CBY37808.1 - 0.0013 18.4 0.4 0.65 9.5 0.0 3.7 2 1 2 4 4 4 2 CLASP N terminal MMS19_C PF12460.8 CBY37808.1 - 0.0016 17.7 3.0 6.6 5.7 0.0 3.3 2 1 0 3 3 3 2 RNAPII transcription regulator C-terminal DUF1349 PF07081.11 CBY37808.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PDCD2_C PF04194.13 CBY37810.1 - 1.1e-24 87.5 0.5 1.1e-24 87.5 0.5 2.5 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Cytomega_UL20A PF05984.12 CBY37810.1 - 0.026 14.8 0.4 0.071 13.4 0.1 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein ANAPC4_WD40 PF12894.7 CBY37811.1 - 0.0011 19.2 0.0 0.13 12.6 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 CBY37811.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like ECH_1 PF00378.20 CBY37812.1 - 1.3e-54 185.2 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY37812.1 - 3.9e-13 49.6 0.0 4.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4889 PF16230.5 CBY37812.1 - 0.0024 18.1 0.4 0.037 14.3 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4889) Peptidase_S49 PF01343.18 CBY37812.1 - 0.0035 17.3 0.4 0.47 10.4 0.0 2.7 2 1 0 3 3 3 1 Peptidase family S49 Carboxyl_trans PF01039.22 CBY37812.1 - 0.062 11.9 0.3 0.86 8.2 0.3 2.0 1 1 1 2 2 2 0 Carboxyl transferase domain T3SS_basalb_I PF17001.5 CBY37812.1 - 0.08 13.5 0.2 0.25 12.0 0.1 1.8 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI SURF4 PF02077.15 CBY37813.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 SURF4 family LRR_9 PF14580.6 CBY37815.1 - 0.038 13.5 0.2 0.049 13.1 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeat EBV-NA3 PF05009.12 CBY37816.1 - 0.81 9.2 6.2 14 5.2 0.1 2.7 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) zf-C2H2_4 PF13894.6 CBY37817.1 - 0.001 19.7 25.8 0.019 15.8 1.1 3.9 3 1 1 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY37817.1 - 0.0019 18.5 22.3 0.087 13.3 0.6 3.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY37817.1 - 0.0037 17.5 21.0 0.11 12.8 2.9 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY37817.1 - 0.65 10.5 17.5 0.37 11.3 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBY37817.1 - 0.67 10.3 17.9 18 5.7 9.9 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY37817.1 - 9.6 6.1 16.9 0.44 10.3 4.0 3.1 2 1 1 3 3 3 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 CBY37818.1 - 4.4e-09 36.3 12.8 8.5e-05 22.8 1.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY37818.1 - 1.2e-06 28.7 0.4 1.2e-06 28.7 0.4 3.3 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY37818.1 - 1.3e-06 28.7 9.9 0.0061 17.3 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY37818.1 - 6.5e-06 26.0 5.5 0.00073 19.5 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY37818.1 - 0.00045 20.4 9.0 0.15 12.4 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY37818.1 - 0.0013 19.1 6.2 0.03 14.7 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 CBY37818.1 - 0.02 15.1 5.1 0.046 13.9 0.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 CBY37818.1 - 0.038 14.1 3.2 0.14 12.3 3.2 2.1 1 1 0 1 1 1 0 Zinc ribbon domain PHD PF00628.29 CBY37818.1 - 0.071 13.0 3.4 0.71 9.8 0.6 2.6 2 1 0 2 2 2 0 PHD-finger zf-Di19 PF05605.12 CBY37818.1 - 0.074 13.4 2.9 0.16 12.3 2.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 CBY37818.1 - 0.11 12.5 3.9 3.4 7.7 3.1 2.3 1 1 1 2 2 2 0 zinc-ribbons Zf_RING PF16744.5 CBY37818.1 - 0.28 11.3 7.1 14 5.9 0.4 3.5 2 1 1 3 3 3 0 KIAA1045 RING finger Vps39_2 PF10367.9 CBY37818.1 - 0.65 10.5 10.6 8.4 6.9 5.5 3.0 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DOR PF14839.6 CBY37818.1 - 1.7 8.5 6.4 1.1 9.1 2.3 1.9 2 0 0 2 2 2 0 DOR family zf-MYST PF17772.1 CBY37818.1 - 2 8.1 9.0 1.7 8.3 1.7 2.9 2 1 1 3 3 3 0 MYST family zinc finger domain zf-CCHC_2 PF13696.6 CBY37818.1 - 2.3 8.2 6.9 9.2 6.2 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle Neur_chan_memb PF02932.16 CBY37819.1 - 4.3 7.3 11.4 4.4 7.3 11.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAP_central PF04928.17 CBY37820.1 - 4.2e-95 317.5 0.0 6e-94 313.7 0.0 2.2 1 1 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBY37820.1 - 1.6e-19 70.2 0.2 1.4e-15 57.4 0.2 3.6 1 1 2 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBY37820.1 - 7.8e-10 38.9 0.0 2.3e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Strabismus PF06638.11 CBY37821.1 - 1.3e-203 677.3 0.7 1.5e-203 677.0 0.7 1.0 1 0 0 1 1 1 1 Strabismus protein BNIP3 PF06553.12 CBY37821.1 - 1.2 8.7 5.9 2.6 7.7 5.9 1.4 1 0 0 1 1 1 0 BNIP3 Caleosin PF05042.13 CBY37823.1 - 0.024 14.6 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Caleosin related protein DUF16 PF01519.16 CBY37823.1 - 0.1 13.1 1.7 0.15 12.5 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Gal-3-0_sulfotr PF06990.11 CBY37824.1 - 5.9e-14 51.8 0.6 1.8e-13 50.2 0.6 1.6 2 0 0 2 2 2 1 Galactose-3-O-sulfotransferase Reprolysin PF01421.19 CBY37825.1 - 1.6e-13 51.0 0.0 1.7e-12 47.7 0.0 2.5 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Sulfotransfer_3 PF13469.6 CBY37825.1 - 1.2e-11 45.4 0.0 2.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Sulfotransferase family Reprolysin_5 PF13688.6 CBY37825.1 - 1.1e-10 42.0 0.1 2.1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY37825.1 - 5.7e-08 33.3 0.2 1.2e-07 32.3 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CBY37825.1 - 1.8e-07 31.9 30.4 1.8e-07 31.9 30.4 2.8 2 1 0 2 2 2 1 Disintegrin Reprolysin_2 PF13574.6 CBY37825.1 - 1.8e-05 24.7 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CBY37825.1 - 3.5e-05 23.5 0.3 6.1e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CBY37825.1 - 0.0036 16.9 1.1 0.0062 16.2 0.2 1.8 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase PEMT PF04191.13 CBY37825.1 - 0.0055 17.1 2.3 0.017 15.5 2.3 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Peptidase_M10 PF00413.24 CBY37825.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Matrixin DUF3810 PF12725.7 CBY37825.1 - 0.018 14.4 0.2 0.018 14.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_M54 PF07998.11 CBY37825.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M54 ICMT PF04140.14 CBY37825.1 - 0.28 11.6 1.5 0.91 10.0 0.3 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family COesterase PF00135.28 CBY37826.1 - 1.4e-17 63.8 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY37826.1 - 0.052 13.4 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold SOBP PF15279.6 CBY37827.1 - 0.086 13.4 6.5 0.11 13.1 6.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_C2 PF00648.21 CBY37828.1 - 7.7e-66 222.1 2.5 2.1e-65 220.7 2.5 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Myosin_head PF00063.21 CBY37829.1 - 5.4e-190 633.0 1.3 6.3e-190 632.8 1.3 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CBY37829.1 - 0.013 15.4 1.1 0.035 14.0 1.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CBY37829.1 - 0.025 14.8 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY37829.1 - 0.075 12.8 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CBY37829.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region API5 PF05918.11 CBY37830.1 - 0.035 12.9 11.0 0.026 13.4 7.3 2.2 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Vfa1 PF08432.10 CBY37832.1 - 0.00019 21.8 4.4 0.00019 21.8 4.4 1.8 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 RPAP2_Rtr1 PF04181.13 CBY37834.1 - 1.7e-18 66.7 1.4 3.8e-18 65.6 1.4 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Sin3a_C PF16879.5 CBY37834.1 - 0.0032 17.2 0.7 0.0032 17.2 0.7 1.8 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein COQ7 PF03232.13 CBY37835.1 - 5.6e-70 234.6 0.6 6.4e-70 234.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CBY37835.1 - 0.0024 18.2 0.2 0.007 16.8 0.2 1.8 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 CBY37835.1 - 0.016 15.4 0.2 0.073 13.3 0.0 2.0 1 1 1 2 2 2 0 Ferritin-like domain DUF3730 PF12530.8 CBY37835.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Ssu72 PF04722.13 CBY37838.1 - 5e-72 241.5 1.4 5.6e-72 241.3 1.4 1.0 1 0 0 1 1 1 1 Ssu72-like protein RRM_1 PF00076.22 CBY37839.1 - 3e-17 62.2 0.0 4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY37839.1 - 5.9e-06 25.9 0.0 7.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY37839.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain CCDC71L PF15374.6 CBY37839.1 - 0.084 12.1 5.5 0.096 11.9 5.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PRE_C2HC PF07530.11 CBY37839.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers RNA_bind PF08675.11 CBY37839.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain I-set PF07679.16 CBY37840.1 - 7.4e-79 259.9 0.0 1.4e-17 63.5 0.0 7.2 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY37840.1 - 7.8e-63 209.0 0.4 6e-13 49.2 0.0 7.7 7 0 0 7 7 7 6 Immunoglobulin domain ig PF00047.25 CBY37840.1 - 3e-31 107.4 9.0 1.3e-07 31.7 0.1 6.8 8 0 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CBY37840.1 - 3.2e-24 85.0 2.0 1.2e-06 28.7 0.0 5.8 6 0 0 6 6 6 3 Immunoglobulin domain V-set PF07686.17 CBY37840.1 - 2.1e-12 47.2 5.0 0.064 13.4 0.0 7.7 4 3 4 8 8 8 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY37840.1 - 4.9e-09 36.1 7.1 0.1 12.6 0.2 5.7 6 1 1 7 7 7 3 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY37840.1 - 6.8e-08 32.5 0.0 0.031 14.3 0.0 6.1 7 1 0 7 7 7 1 Penicillin-Binding Protein C-terminus Family Izumo-Ig PF16706.5 CBY37840.1 - 3.8e-06 26.9 0.1 0.36 10.9 0.0 4.8 6 0 0 6 6 6 1 Izumo-like Immunoglobulin domain Ig_4 PF16680.5 CBY37840.1 - 0.0011 19.2 1.3 7.1 7.0 0.0 5.0 5 0 0 5 5 5 1 T-cell surface glycoprotein CD3 delta chain MBG_2 PF18676.1 CBY37840.1 - 0.015 15.9 3.2 1.4 9.6 0.0 4.6 7 0 0 7 7 5 0 MBG domain (YGX type) DUF4198 PF10670.9 CBY37840.1 - 0.08 13.3 0.1 4 7.7 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4198) Sec-ASP3 PF15432.6 CBY37840.1 - 0.13 12.4 0.1 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Accessory Sec secretory system ASP3 DUF3086 PF11285.8 CBY37841.1 - 0.00012 21.3 0.3 0.0002 20.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) Macoilin PF09726.9 CBY37841.1 - 4.2 5.8 11.9 4.7 5.6 11.9 1.1 1 0 0 1 1 1 0 Macoilin family AHD PF17793.1 CBY37842.1 - 0.088 12.6 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Glyco_hydro_47 PF01532.20 CBY37843.1 - 6.8e-97 325.2 0.0 9.9e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 CBY37844.1 - 0.0025 16.8 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Guanylate_cyc PF00211.20 CBY37845.1 - 5.9e-49 166.2 0.0 8.7e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 CBY37845.1 - 8.7e-25 87.6 0.1 1.6e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37845.1 - 3.2e-24 85.6 0.1 5.7e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HNOBA PF07701.14 CBY37845.1 - 2.2e-05 24.0 0.4 2.2e-05 24.0 0.4 1.7 2 0 0 2 2 2 1 Heme NO binding associated FAM216B PF15107.6 CBY37848.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM216B protein family HOOK PF05622.12 CBY37849.1 - 0.032 12.4 0.7 0.04 12.1 0.7 1.0 1 0 0 1 1 1 0 HOOK protein RhoGEF PF00621.20 CBY37850.1 - 2.3e-23 83.4 0.4 4.3e-23 82.5 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain CEP44 PF15007.6 CBY37850.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 zf-H2C2_2 PF13465.6 CBY37851.1 - 0.041 14.3 0.3 0.041 14.3 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Shisa PF13908.6 CBY37853.1 - 0.00012 22.4 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 CBY37853.1 - 0.0095 15.7 0.9 0.013 15.2 0.9 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Baculo_F PF12259.8 CBY37853.1 - 0.02 13.4 0.1 0.024 13.2 0.1 1.0 1 0 0 1 1 1 0 Baculovirus F protein Cadherin_C_2 PF16492.5 CBY37853.1 - 0.041 14.6 0.0 0.057 14.2 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal SID-1_RNA_chan PF13965.6 CBY37853.1 - 0.046 12.1 0.0 0.048 12.1 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.15 CBY37853.1 - 0.06 14.0 0.0 0.077 13.6 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family SARAF PF06682.12 CBY37853.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis EphA2_TM PF14575.6 CBY37853.1 - 0.14 13.1 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.11 CBY37853.1 - 0.16 11.9 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein MAP17 PF15807.5 CBY37853.1 - 0.17 12.2 0.1 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 VWA PF00092.28 CBY37854.1 - 3.4e-14 53.5 0.2 4.8e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY37854.1 - 6.2e-06 26.8 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Mab-21 PF03281.14 CBY37855.1 - 1e-70 238.4 0.0 1.2e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Mab-21 protein DUF4834 PF16118.5 CBY37856.1 - 0.025 15.5 1.6 1.2 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RNA_pol_Rpc4 PF05132.14 CBY37856.1 - 0.032 14.7 3.2 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Membralin PF09746.9 CBY37856.1 - 0.046 12.8 1.0 0.078 12.0 0.2 1.7 1 1 1 2 2 2 0 Tumour-associated protein YqfQ PF14181.6 CBY37856.1 - 1.8 8.7 12.7 1.5 9.0 4.9 2.2 2 0 0 2 2 2 0 YqfQ-like protein CPSF100_C PF13299.6 CBY37856.1 - 6.5 6.9 7.6 5.3 7.2 2.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal XhlA PF10779.9 CBY37858.1 - 0.025 14.8 4.1 0.99 9.7 0.7 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Vac_Fusion PF02346.16 CBY37858.1 - 0.055 13.1 0.7 0.7 9.6 0.0 2.6 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 FlxA PF14282.6 CBY37858.1 - 0.096 12.7 4.2 0.21 11.6 2.6 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF4164 PF13747.6 CBY37858.1 - 0.11 12.8 2.7 1.8 8.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1515 PF07439.11 CBY37858.1 - 0.27 11.3 2.6 13 5.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FAM76 PF16046.5 CBY37858.1 - 0.32 10.3 1.5 0.38 10.1 1.5 1.2 1 0 0 1 1 1 0 FAM76 protein Moricin PF06451.11 CBY37858.1 - 1.1 9.1 2.9 8.2 6.3 0.7 2.4 2 0 0 2 2 2 0 Moricin Fib_alpha PF08702.10 CBY37858.1 - 1.7 8.8 5.3 5.2 7.2 5.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBY37858.1 - 4.1 7.5 9.4 16 5.5 0.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box PF00646.33 CBY37860.1 - 7.8e-05 22.4 0.1 0.002 18.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY37860.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.21 CBY37860.1 - 0.018 15.2 7.2 0.051 13.8 7.2 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3797 PF12677.7 CBY37860.1 - 0.043 13.7 2.2 0.12 12.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CEBP_ZZ PF16366.5 CBY37860.1 - 0.6 10.4 7.5 1.5 9.1 7.5 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Neuropeptide_S PF14993.6 CBY37861.1 - 0.095 12.5 0.2 0.4 10.5 0.1 2.0 2 0 0 2 2 2 0 Neuropeptide S precursor protein GAS2 PF02187.17 CBY37862.1 - 8.2e-20 70.7 0.1 1.4e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Med3 PF11593.8 CBY37862.1 - 1.4 8.0 8.8 1.6 7.9 8.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FPP PF05911.11 CBY37863.1 - 0.0027 16.0 33.8 0.0032 15.7 33.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil AbLIM_anchor PF16182.5 CBY37863.1 - 0.054 13.3 11.0 0.07 12.9 11.0 1.2 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM SabA_adhesion PF18304.1 CBY37863.1 - 0.13 11.5 11.3 0.16 11.2 11.3 1.1 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Caldesmon PF02029.15 CBY37863.1 - 0.42 9.3 30.4 0.51 9.1 30.4 1.1 1 0 0 1 1 1 0 Caldesmon DivIC PF04977.15 CBY37863.1 - 0.62 9.9 0.0 0.62 9.9 0.0 5.1 2 1 3 5 5 5 0 Septum formation initiator Fez1 PF06818.15 CBY37863.1 - 0.9 10.0 35.6 0.52 10.7 33.0 1.7 1 1 1 2 2 2 0 Fez1 Hema_stalk PF08720.10 CBY37863.1 - 1.8 8.2 7.1 0.3 10.8 2.1 2.1 1 1 0 2 2 2 0 Influenza C hemagglutinin stalk Gp_dh_N PF00044.24 CBY37863.1 - 2.1 8.8 5.2 0.87 10.0 1.7 2.1 1 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ApoO PF09769.9 CBY37863.1 - 8.8 6.3 5.8 1.8 8.5 1.3 2.0 2 1 0 2 2 2 0 Apolipoprotein O Phospholip_A2_1 PF00068.19 CBY37864.1 - 1.2e-16 61.1 12.6 2.4e-16 60.2 12.6 1.4 1 0 0 1 1 1 1 Phospholipase A2 Rhodanese PF00581.20 CBY37865.1 - 0.022 15.3 0.0 0.18 12.3 0.0 2.5 1 1 0 1 1 1 0 Rhodanese-like domain LCD1 PF09798.9 CBY37865.1 - 1.7 7.1 6.5 3.2 6.1 6.5 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein Cyclin_C_2 PF16899.5 CBY37866.1 - 4.9e-18 65.4 0.0 6.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CBY37866.1 - 2.5e-10 40.2 1.3 4e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY37866.1 - 0.063 13.4 0.1 7.4 6.7 0.0 2.8 3 0 0 3 3 3 0 Cyclin, C-terminal domain RNA_GG_bind PF10258.9 CBY37867.1 - 5.8e-20 71.1 0.4 1.3e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 PHAX RNA-binding domain DUF4707 PF15806.5 CBY37867.1 - 0.093 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) DUF3287 PF11690.8 CBY37867.1 - 0.16 11.7 1.7 0.19 11.4 0.4 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) DASH_Dad3 PF08656.10 CBY37867.1 - 0.51 10.5 3.9 8.6 6.5 0.0 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 DUF3987 PF13148.6 CBY37867.1 - 3.6 6.5 8.0 0.85 8.6 4.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) EF-hand_5 PF13202.6 CBY37868.1 - 0.006 16.0 2.3 0.15 11.6 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 CBY37868.1 - 0.054 13.1 4.8 0.27 10.9 0.0 3.5 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 CBY37868.1 - 0.091 12.7 3.5 7.8 6.7 0.1 3.8 4 0 0 4 4 4 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY37868.1 - 0.37 11.1 5.8 2 8.8 0.8 3.5 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.6 CBY37868.1 - 8.5 6.9 8.6 1.5 9.3 0.9 3.4 3 1 1 4 4 4 0 EF-hand domain pair Prominin PF05478.11 CBY37869.1 - 0.0037 15.3 3.5 0.0064 14.5 3.5 1.3 1 0 0 1 1 1 1 Prominin SYCP2_SLD PF18584.1 CBY37869.1 - 0.086 13.1 1.0 0.37 11.0 0.4 2.2 1 1 1 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain GIT1_C PF12205.8 CBY37869.1 - 0.12 12.5 7.6 0.34 11.0 7.6 1.8 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term LRR_4 PF12799.7 CBY37870.1 - 0.0055 17.1 4.1 0.3 11.6 0.1 3.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY37870.1 - 0.0068 16.1 1.8 0.76 9.6 0.0 3.2 1 1 2 3 3 3 3 Leucine rich repeat Nucleopor_Nup85 PF07575.13 CBY37871.1 - 0.034 12.7 0.3 0.049 12.2 0.3 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin GCK PF07802.11 CBY37871.1 - 0.059 13.8 0.8 0.25 11.8 0.3 2.1 2 0 0 2 2 2 0 GCK domain CHCH PF06747.13 CBY37871.1 - 5.2 7.3 5.1 1.1 9.4 0.3 2.5 3 0 0 3 3 3 0 CHCH domain HNF-1_N PF04814.13 CBY37872.1 - 4.2e-10 40.6 0.1 4.6e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Thioredoxin_16 PF18569.1 CBY37873.1 - 0.0066 16.6 0.6 0.016 15.3 0.6 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain SLATT_6 PF18169.1 CBY37873.1 - 0.11 12.1 15.7 2.1 7.9 0.3 3.5 1 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 DUF4140 PF13600.6 CBY37873.1 - 0.17 12.3 9.1 1.4 9.4 2.4 3.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HALZ PF02183.18 CBY37873.1 - 0.19 12.0 9.6 0.31 11.3 1.4 3.8 5 0 0 5 5 4 0 Homeobox associated leucine zipper DUF2524 PF10732.9 CBY37873.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) WXG100 PF06013.12 CBY37873.1 - 0.21 11.8 4.4 1.9 8.8 1.5 3.2 4 0 0 4 4 3 0 Proteins of 100 residues with WXG Spc7 PF08317.11 CBY37873.1 - 0.24 10.3 26.0 0.098 11.5 16.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_int_SAM_2 PF12834.7 CBY37873.1 - 0.25 12.1 6.5 20 5.9 0.1 3.3 2 1 1 3 3 3 0 Phage integrase, N-terminal PRKG1_interact PF15898.5 CBY37873.1 - 0.42 11.5 22.3 0.87 10.5 8.8 3.5 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain BST2 PF16716.5 CBY37873.1 - 1.3 9.7 14.7 0.16 12.6 6.0 3.4 1 1 3 5 5 5 0 Bone marrow stromal antigen 2 Med10 PF09748.9 CBY37873.1 - 1.8 8.6 10.2 4.5 7.3 1.3 3.2 1 1 2 3 3 3 0 Transcription factor subunit Med10 of Mediator complex DivIC PF04977.15 CBY37873.1 - 1.9 8.3 13.9 20 5.1 0.0 3.6 2 1 0 2 2 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 CBY37873.1 - 2.2 9.0 24.0 2.7 8.6 9.3 3.5 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 CBY37873.1 - 2.3 8.3 13.3 2.1 8.4 3.3 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APC_N_CC PF16689.5 CBY37873.1 - 2.7 8.1 7.4 1.6 8.9 2.5 2.9 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1664 PF07889.12 CBY37873.1 - 3.6 7.7 15.7 0.69 10.0 5.9 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 CBY37873.1 - 4.6 7.9 7.8 0.46 11.1 1.4 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 CBY37873.1 - 4.8 7.7 26.2 3.3 8.2 2.7 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region KxDL PF10241.9 CBY37873.1 - 5.5 7.3 12.1 2.3 8.6 0.1 3.9 2 2 0 3 3 3 0 Uncharacterized conserved protein SKA2 PF16740.5 CBY37873.1 - 9.9 6.0 14.0 0.76 9.6 4.1 3.3 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Acyl-CoA_dh_1 PF00441.24 CBY37874.1 - 5.8e-29 101.2 0.8 9.3e-29 100.6 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBY37874.1 - 1e-16 61.6 0.0 2.9e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY37874.1 - 7.9e-14 51.6 0.0 2.1e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY37874.1 - 1.9e-08 34.7 0.7 3.5e-08 33.8 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2339 PF10101.9 CBY37875.1 - 0.92 8.0 11.2 0.25 9.9 4.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Peptidase_M14 PF00246.24 CBY37876.1 - 2e-77 260.8 1.2 2.8e-77 260.4 1.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY37876.1 - 6.9e-14 52.0 0.6 1.9e-13 50.6 0.5 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Glyco_hydro_10 PF00331.20 CBY37877.1 - 9.8e-27 93.9 5.3 2.1e-26 92.8 5.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_4_9 PF02018.17 CBY37877.1 - 0.027 14.7 0.1 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain EGF_CA PF07645.15 CBY37878.1 - 3.3e-35 120.0 61.6 1.5e-12 47.5 5.8 4.3 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.7 CBY37878.1 - 7e-24 83.7 51.0 1.4e-07 31.6 6.0 4.8 4 0 0 4 4 4 4 EGF domain cEGF PF12662.7 CBY37878.1 - 3e-13 49.4 40.7 0.00038 20.3 2.8 5.0 4 0 0 4 4 4 4 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY37878.1 - 1e-09 38.5 52.4 0.0019 18.4 5.2 4.7 4 2 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY37878.1 - 9.8e-09 35.4 58.7 0.00073 19.8 9.5 5.2 5 1 1 6 6 6 4 EGF-like domain EGF_MSP1_1 PF12946.7 CBY37878.1 - 1.6e-05 24.8 43.1 0.065 13.3 3.1 4.6 4 0 0 4 4 4 4 MSP1 EGF domain 1 hEGF PF12661.7 CBY37878.1 - 0.0032 18.1 46.9 0.023 15.3 5.4 6.1 5 0 0 5 5 5 3 Human growth factor-like EGF Helicase_RecD PF05127.14 CBY37878.1 - 0.17 11.8 2.2 2.7 7.8 0.0 2.8 1 1 1 3 3 3 0 Helicase EGF_2 PF07974.13 CBY37878.1 - 1.2 9.6 47.5 1.2 9.5 6.7 5.2 4 1 0 4 4 4 0 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY37878.1 - 9.9 6.6 50.7 0.099 13.0 13.5 4.9 4 3 0 4 4 4 0 Pvs28 EGF domain EGF_CA PF07645.15 CBY37879.1 - 1.1e-100 329.6 263.0 6.6e-09 35.8 8.3 16.8 16 0 0 16 16 16 16 Calcium-binding EGF domain EGF_3 PF12947.7 CBY37879.1 - 5.3e-57 189.7 243.7 4.3e-09 36.4 8.5 18.5 16 2 3 19 19 19 16 EGF domain cEGF PF12662.7 CBY37879.1 - 2.9e-55 183.7 136.9 1.4e-07 31.3 0.3 16.8 15 0 0 15 15 15 13 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY37879.1 - 6.8e-17 61.2 190.3 3e-05 24.0 2.4 15.7 16 1 0 16 16 16 8 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY37879.1 - 7.2e-14 51.8 235.9 0.0056 16.9 3.7 17.2 14 2 1 16 16 16 12 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY37879.1 - 7.6e-14 51.7 224.1 0.0074 16.6 5.8 18.3 17 1 0 17 17 17 13 EGF-like domain hEGF PF12661.7 CBY37879.1 - 1.5e-08 34.9 203.2 0.0094 16.6 2.5 20.8 20 0 0 20 20 20 11 Human growth factor-like EGF ITI_HC_C PF06668.12 CBY37879.1 - 4.3e-06 26.5 0.1 6.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Plasmod_Pvs28 PF06247.11 CBY37879.1 - 0.0047 17.2 5.1 0.0047 17.2 5.1 16.8 13 3 1 15 15 15 7 Pvs28 EGF domain UPAR_LY6 PF00021.21 CBY37880.1 - 0.03 15.0 3.4 0.03 15.0 3.4 2.1 1 1 1 2 2 2 0 u-PAR/Ly-6 domain Opy2 PF09463.10 CBY37880.1 - 5.2 7.5 9.3 2.3 8.6 0.2 3.3 3 0 0 3 3 3 0 Opy2 protein Aldedh PF00171.22 CBY37882.1 - 7.3e-19 67.6 0.0 8.3e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3421 PF11901.8 CBY37884.1 - 1.9e-17 63.3 0.0 1.1e-05 25.4 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) ELP6 PF09807.9 CBY37887.1 - 0.00046 19.7 0.0 0.00079 18.9 0.0 1.5 1 1 0 1 1 1 1 Elongation complex protein 6 Cytidylate_kin PF02224.18 CBY37887.1 - 0.02 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Mab-21 PF03281.14 CBY37890.1 - 5.4e-24 85.0 0.0 8.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Mab-21 protein MIP PF00230.20 CBY37891.1 - 3.1e-23 82.7 2.8 3.5e-23 82.5 2.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 CBY37891.1 - 2.9 8.3 6.8 0.92 9.9 0.2 2.6 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V AMP-binding PF00501.28 CBY37892.1 - 2.4e-24 85.7 0.4 3.1e-24 85.4 0.4 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY37892.1 - 0.0069 17.3 0.0 0.012 16.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 CBY37892.1 - 0.046 13.7 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Cyclophilin-like family AMP-binding PF00501.28 CBY37893.1 - 3.8e-21 75.2 0.0 5.1e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.7 CBY37894.1 - 2.8e-30 104.7 0.9 6.4e-18 65.1 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY37894.1 - 6.4e-27 93.6 3.9 3.4e-09 37.1 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBY37894.1 - 6.1e-26 89.7 11.7 1.2e-07 31.8 0.4 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBY37894.1 - 2.5e-25 88.2 6.8 3.1e-08 33.7 0.4 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY37894.1 - 3.8e-20 69.8 3.9 4e-05 23.7 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat COG4 PF08318.12 CBY37894.1 - 0.28 10.2 1.9 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 COG4 transport protein NUDIX PF00293.28 CBY37898.1 - 8.5e-07 29.1 0.7 9.8e-07 28.9 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain EXS PF03124.14 CBY37900.1 - 2.8e-78 263.6 19.9 4.1e-78 263.0 19.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CBY37900.1 - 3.7e-24 86.4 20.4 2.1e-09 37.8 0.8 3.3 1 1 2 3 3 3 3 SPX domain DUF5638 PF18688.1 CBY37900.1 - 0.21 11.9 2.3 0.76 10.1 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF4590 PF15257.6 CBY37901.1 - 4.2e-43 145.9 0.7 8.8e-43 144.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4590) DUF4542 PF15075.6 CBY37901.1 - 0.34 11.3 0.1 0.34 11.3 0.1 3.3 3 2 0 3 3 3 0 Domain of unknown function (DUF4542) DnaJ PF00226.31 CBY37902.1 - 9.4e-23 80.1 3.5 9.4e-23 80.1 3.5 2.0 2 0 0 2 2 2 1 DnaJ domain INCENP_ARK-bind PF03941.15 CBY37903.1 - 4.8e-09 36.0 0.1 1.2e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region SAP PF02037.27 CBY37903.1 - 3.1e-05 23.6 0.7 5.2e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 SAP domain IBB PF01749.20 CBY37903.1 - 0.01 16.2 11.0 0.044 14.2 11.0 2.2 1 0 0 1 1 1 0 Importin beta binding domain LRR_8 PF13855.6 CBY37905.1 - 4.8e-24 83.9 12.7 1.7e-11 43.7 0.4 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY37905.1 - 1.9e-07 31.3 11.7 0.002 18.5 1.2 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY37905.1 - 1.7e-06 28.0 0.6 3.4e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBY37905.1 - 6.8e-06 25.9 4.4 0.48 11.2 1.1 5.2 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY37905.1 - 9.3e-05 22.2 8.8 0.73 10.0 1.0 5.0 5 0 0 5 5 5 3 Leucine Rich repeat DPBB_1 PF03330.18 CBY37905.1 - 0.18 12.1 0.1 0.49 10.7 0.0 1.8 2 0 0 2 2 2 0 Lytic transglycolase Arm PF00514.23 CBY37906.1 - 4.7e-53 175.7 29.0 0.00037 20.4 0.0 13.4 13 0 0 13 13 13 12 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBY37906.1 - 3.7e-16 59.3 14.0 1.9e-06 28.1 0.1 7.4 2 2 8 10 10 10 5 HEAT repeats Adaptin_N PF01602.20 CBY37906.1 - 3.1e-11 42.6 5.3 2.2e-07 29.8 0.0 3.7 1 1 0 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 CBY37906.1 - 3.1e-09 37.0 8.2 3.6 7.7 0.1 7.0 4 2 2 7 7 7 3 V-ATPase subunit H HEAT PF02985.22 CBY37906.1 - 6.1e-09 35.4 11.9 0.21 12.0 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CBY37906.1 - 1.1e-07 32.2 12.6 0.0048 17.4 0.2 7.7 8 1 0 8 8 8 1 HEAT-like repeat Proteasom_PSMB PF10508.9 CBY37906.1 - 2.1e-06 26.5 3.2 6.4e-06 24.9 0.3 2.5 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 CBY37906.1 - 2.1e-06 27.4 10.4 0.048 13.1 0.1 5.7 3 2 2 6 6 6 1 Armadillo-like KAP PF05804.12 CBY37906.1 - 2.4e-06 26.0 0.6 1.2 7.2 0.0 3.9 1 1 1 4 4 4 4 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 CBY37906.1 - 1.9e-05 24.1 0.3 0.78 9.0 0.0 4.4 1 1 3 4 4 4 2 V-ATPase subunit H Cnd1 PF12717.7 CBY37906.1 - 0.00036 20.6 4.2 1.9 8.5 0.1 4.4 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CTNNBL PF08216.11 CBY37906.1 - 0.0011 19.1 0.1 21 5.4 0.0 5.0 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear E3_UbLigase_R4 PF13764.6 CBY37906.1 - 0.014 13.6 3.4 0.06 11.5 0.0 2.9 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase UBR4 UPF0147 PF03685.13 CBY37906.1 - 0.059 13.4 0.8 7.8 6.6 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0147) Pes-10 PF07149.11 CBY37906.1 - 7.8 5.4 7.2 0.92 8.5 1.1 2.5 3 1 0 3 3 3 0 Pes-10 ANAPC4_WD40 PF12894.7 CBY37907.1 - 2.7e-06 27.6 0.0 1 9.7 0.1 5.3 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 CBY37907.1 - 0.00059 18.7 0.7 2 7.1 0.0 4.2 2 2 3 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 CBY37907.1 - 0.014 16.2 0.3 97 4.1 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 CBY37907.1 - 0.04 13.9 1.3 3.4 7.7 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 CBY37907.1 - 0.042 12.9 2.1 2.9 6.8 0.0 2.8 2 1 1 3 3 3 0 Coatomer WD associated region DUF4904 PF16247.5 CBY37907.1 - 0.051 13.4 0.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) Thiolase_C PF02803.18 CBY37907.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain PHD PF00628.29 CBY37908.1 - 1.3e-16 60.2 22.2 4.4e-08 32.9 12.7 2.8 2 0 0 2 2 2 2 PHD-finger FHA PF00498.26 CBY37908.1 - 6.8e-07 29.6 0.0 2.7e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 FHA domain C1_1 PF00130.22 CBY37908.1 - 0.0029 17.5 11.2 0.063 13.2 0.6 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CBY37908.1 - 0.0078 15.8 0.2 0.0078 15.8 0.2 2.9 3 1 0 3 3 3 2 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 CBY37908.1 - 0.023 14.3 1.0 0.023 14.3 1.0 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 CBY37908.1 - 0.063 12.8 18.3 0.32 10.6 0.1 3.1 3 0 0 3 3 3 0 PHD-finger Zf_RING PF16744.5 CBY37908.1 - 0.087 13.0 0.1 0.087 13.0 0.1 2.8 2 1 0 2 2 2 0 KIAA1045 RING finger LLGL PF08366.13 CBY37909.1 - 1.7e-21 76.5 0.0 1.1e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 LLGL2 WD40 PF00400.32 CBY37909.1 - 1.7e-05 25.4 0.1 0.7 10.9 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37909.1 - 0.001 19.4 0.1 14 6.1 0.0 4.9 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain YibE_F PF07907.11 CBY37910.1 - 2.6 7.5 18.2 2.9 7.3 2.6 2.7 2 1 0 2 2 2 0 YibE/F-like protein Cation_efflux PF01545.21 CBY37910.1 - 9.7 5.9 20.9 44 3.7 20.9 1.9 1 1 0 1 1 1 0 Cation efflux family CHGN PF05679.16 CBY37913.1 - 4.7e-17 62.0 0.2 1.4e-13 50.6 0.2 2.1 2 0 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Glycos_transf_2 PF00535.26 CBY37913.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Nore1-SARAH PF16517.5 CBY37914.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DIT1_PvcA PF05141.12 CBY37914.1 - 0.022 14.2 0.1 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein GLTP PF08718.11 CBY37915.1 - 2.1e-41 141.7 1.5 7e-41 140.0 0.1 2.5 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PH PF00169.29 CBY37915.1 - 2.9e-10 40.6 0.0 1e-09 38.8 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 CBY37915.1 - 6.4e-06 26.4 0.1 1.7e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY37915.1 - 4.6e-05 23.8 0.6 0.001 19.5 0.6 3.2 1 1 0 1 1 1 1 Pleckstrin homology domain HAUS2 PF15003.6 CBY37915.1 - 1.5 8.5 7.4 4.6 6.9 0.8 2.9 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 2 NGP1NT PF08153.12 CBY37916.1 - 2.4e-47 160.3 0.4 2.4e-47 160.3 0.4 2.5 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBY37916.1 - 1.3e-15 57.5 0.0 8.6e-13 48.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY37916.1 - 1.6e-06 27.7 0.1 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY37916.1 - 0.002 18.0 0.8 0.0058 16.5 0.0 2.1 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 CBY37916.1 - 0.01 15.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family MOZ_SAS PF01853.18 CBY37917.1 - 1.7e-80 268.9 0.1 2.3e-80 268.5 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY37917.1 - 1.9e-21 75.4 3.6 5e-21 74.1 3.6 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CBY37917.1 - 0.0017 18.7 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_IclR PF09339.10 CBY37917.1 - 0.023 14.5 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF5427 PF10310.9 CBY37917.1 - 1.7 7.6 19.2 2.6 6.9 19.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Cys_rich_FGFR PF00839.17 CBY37918.1 - 5.5e-35 119.3 20.8 2.5e-12 46.8 0.2 5.3 5 0 0 5 5 5 5 Cysteine rich repeat DapH_N PF08503.10 CBY37918.1 - 0.097 12.9 0.3 1.9 8.7 0.0 2.6 2 1 1 3 3 3 0 Tetrahydrodipicolinate succinyltransferase N-terminal Tmemb_161AB PF10268.9 CBY37919.1 - 9.2e-68 229.0 9.4 6.3e-67 226.2 7.8 2.1 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB RapH_N PF18801.1 CBY37919.1 - 0.053 13.6 2.7 0.089 12.9 0.9 2.1 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF5426 PF17473.2 CBY37919.1 - 0.099 12.9 0.4 0.099 12.9 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5426) Herpes_UL6 PF01763.16 CBY37919.1 - 0.13 10.8 0.6 0.19 10.2 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1891 PF09004.10 CBY37919.1 - 3.7 7.2 5.8 1.9 8.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1891) UPF0242 PF06785.11 CBY37920.1 - 0.0053 16.9 8.8 0.011 15.8 8.8 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Adaptin_binding PF10199.9 CBY37920.1 - 0.97 10.1 9.2 1.6 9.4 4.0 2.6 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 ATP-synt_E PF05680.12 CBY37920.1 - 1.6 9.1 13.0 1.7 9.0 11.2 2.0 2 0 0 2 2 2 0 ATP synthase E chain V_ATPase_I PF01496.19 CBY37920.1 - 1.9 6.3 8.3 2.3 6.0 8.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1840 PF08895.11 CBY37920.1 - 5.3 7.4 11.1 12 6.3 4.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cpn60_TCP1 PF00118.24 CBY37921.1 - 4.5e-155 517.0 16.9 5.5e-155 516.7 16.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family YchF-GTPase_C PF06071.13 CBY37922.1 - 1.7e-35 121.1 1.2 1.7e-35 121.1 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBY37922.1 - 1.2e-21 76.9 0.0 3.9e-21 75.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY37922.1 - 8.5e-07 28.6 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBY37922.1 - 0.014 15.5 0.0 7.6 6.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family TGS PF02824.21 CBY37922.1 - 0.086 12.9 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 TGS domain AAA_14 PF13173.6 CBY37922.1 - 0.09 12.8 0.0 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain GLTP PF08718.11 CBY37923.1 - 9.2e-31 107.1 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pro_isomerase PF00160.21 CBY37924.1 - 2e-48 164.7 0.0 3.6e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CBY37924.1 - 4.7e-09 36.7 0.8 2.1 9.3 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY37924.1 - 0.0091 15.0 0.6 2.5 7.0 0.0 3.5 1 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CBY37924.1 - 0.038 12.7 0.1 0.077 11.7 0.1 1.4 1 0 0 1 1 1 0 Nup133 N terminal like CRM1_C PF08767.11 CBY37924.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal MMS1_N PF10433.9 CBY37924.1 - 0.082 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBFD_NFYB_HMF PF00808.23 CBY37925.1 - 2.1e-29 101.6 0.9 4.4e-29 100.6 0.9 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY37925.1 - 9e-06 26.1 0.4 1.7e-05 25.2 0.3 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CBY37925.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 CBY37925.1 - 0.0022 18.1 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CBY37925.1 - 0.063 13.8 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.10 CBY37925.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RT_RNaseH_2 PF17919.1 CBY37927.1 - 3.1e-21 75.3 0.0 5.4e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY37927.1 - 9.6e-09 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Forkhead PF00250.18 CBY37928.1 - 6.8e-37 125.6 0.0 1.3e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain AAA PF00004.29 CBY37929.1 - 0.088 13.2 1.4 0.92 9.9 0.3 2.3 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ion_trans PF00520.31 CBY37931.1 - 2.9e-08 33.2 19.7 4.6e-08 32.6 19.7 1.4 1 0 0 1 1 1 1 Ion transport protein PDZ PF00595.24 CBY37932.1 - 7.2e-21 74.3 0.0 6.8e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY37932.1 - 2e-16 59.6 0.1 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY37932.1 - 5.1e-05 23.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY37932.1 - 0.011 15.6 0.0 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain p450 PF00067.22 CBY37934.1 - 8e-11 41.3 0.2 1e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SLC3A2_N PF16028.5 CBY37934.1 - 0.15 11.6 0.9 2.3 7.8 0.0 2.5 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus p450 PF00067.22 CBY37935.1 - 2e-24 86.2 0.0 2.3e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CENP-C_C PF11699.8 CBY37937.1 - 0.01 16.0 0.2 0.026 14.7 0.2 1.7 1 0 0 1 1 1 0 Mif2/CENP-C like AT_hook PF02178.19 CBY37937.1 - 0.076 12.9 4.1 0.43 10.6 4.1 2.5 1 0 0 1 1 1 0 AT hook motif Peptidase_S9 PF00326.21 CBY37938.1 - 4.1e-59 199.6 0.0 5e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CBY37938.1 - 5.6e-06 25.4 0.0 9.6e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_3 PF07859.13 CBY37938.1 - 0.022 14.6 0.1 0.16 11.8 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 CBY37938.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CBY37938.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CBY37938.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 CBY37938.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DsbC_N PF10411.9 CBY37938.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus Pkinase PF00069.25 CBY37939.1 - 1.8e-28 99.6 0.0 1.7e-24 86.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37939.1 - 4e-18 65.6 0.0 2.7e-14 53.1 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY37939.1 - 0.16 10.9 0.0 2.4 7.0 0.0 2.0 1 1 1 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 CBY37941.1 - 5.6e-44 150.5 0.0 6.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37941.1 - 3.2e-20 72.5 0.0 4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY37941.1 - 0.0016 17.8 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY37941.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY37941.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGEF PF00621.20 CBY37942.1 - 5.5e-06 26.8 0.7 5.5e-06 26.8 0.7 1.8 2 0 0 2 2 2 1 RhoGEF domain OLF PF02191.16 CBY37944.1 - 2.9e-78 262.8 6.5 3.5e-78 262.6 6.5 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain RPEL PF02755.15 CBY37945.1 - 6.4e-14 51.1 1.1 4.5e-07 29.3 0.1 2.6 2 0 0 2 2 2 2 RPEL repeat PRP3 PF08572.10 CBY37945.1 - 0.029 14.1 15.1 0.046 13.5 15.1 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) UPF0061 PF02696.14 CBY37949.1 - 4.3e-111 372.0 0.1 1e-110 370.7 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3631 PF12307.8 CBY37949.1 - 0.046 13.9 0.1 0.6 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) G10 PF01125.17 CBY37949.1 - 1.3 8.7 6.1 2.3 8.0 0.7 2.6 3 0 0 3 3 3 0 G10 protein DUF2737 PF10930.8 CBY37950.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Ank_2 PF12796.7 CBY37951.1 - 3.7e-10 40.3 0.0 1.6e-07 31.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY37951.1 - 4.2e-07 29.8 0.1 0.011 16.2 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CBY37951.1 - 4.6e-07 30.0 0.0 7.4e-05 23.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY37951.1 - 1.2e-06 29.0 0.1 0.0023 18.4 0.0 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY37951.1 - 0.0026 18.1 0.0 2.3 8.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat STE PF02200.16 CBY37951.1 - 0.031 14.7 1.1 7.5 7.0 0.3 2.5 1 1 1 2 2 2 0 STE like transcription factor AMP-binding PF00501.28 CBY37952.1 - 3.4e-40 137.9 1.9 2.5e-18 65.9 0.0 5.6 6 0 0 6 6 6 5 AMP-binding enzyme Cyclin_N PF00134.23 CBY37953.1 - 5.3e-23 81.1 0.7 9.7e-23 80.3 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain OTCace_N PF02729.21 CBY37953.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Cyclin_C PF02984.19 CBY37953.1 - 0.71 10.0 3.9 1.1 9.3 1.2 2.4 2 1 1 3 3 3 0 Cyclin, C-terminal domain BAH PF01426.18 CBY37955.1 - 1.4e-05 24.9 0.3 9.5e-05 22.2 0.3 2.1 1 1 0 1 1 1 1 BAH domain RIC3 PF15361.6 CBY37956.1 - 1.8e-07 31.6 0.3 1.8e-07 31.6 0.3 2.8 2 2 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 Syndecan PF01034.20 CBY37956.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain PIN_8 PF18476.1 CBY37956.1 - 0.17 11.8 13.6 0.11 12.4 12.1 1.4 1 1 0 1 1 1 0 PIN like domain CorA PF01544.18 CBY37956.1 - 0.23 10.7 4.3 0.92 8.8 4.3 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ABC2_membrane_3 PF12698.7 CBY37956.1 - 0.37 9.9 4.6 0.5 9.4 4.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Lipoprotein_2 PF00921.17 CBY37956.1 - 1.6 8.3 20.4 0.1 12.1 8.9 2.1 2 0 0 2 2 2 0 Borrelia lipoprotein HrpB7 PF09486.10 CBY37956.1 - 1.6 9.1 10.2 0.49 10.8 1.8 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GatB_Yqey PF02637.18 CBY37956.1 - 6.7 6.6 13.3 0.072 13.0 3.0 2.1 2 0 0 2 2 2 0 GatB domain His_Phos_2 PF00328.22 CBY37957.1 - 2.3e-08 33.8 0.1 1.7e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.9 CBY37957.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Guanylylate cyclase LRR_8 PF13855.6 CBY37959.1 - 2e-21 75.5 5.0 2.5e-09 36.8 0.1 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBY37959.1 - 9.5e-12 45.0 5.0 0.0008 19.8 0.0 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY37959.1 - 1.9e-06 27.6 4.7 1 10.2 0.1 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY37959.1 - 8.5e-06 25.4 2.6 0.35 11.0 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich repeat ADH_N PF08240.12 CBY37960.1 - 1.9e-20 72.8 0.0 4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBY37960.1 - 1.4e-18 67.1 0.1 3.8e-18 65.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBY37960.1 - 1.8e-07 30.9 0.3 6.8e-07 29.0 0.3 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CBY37960.1 - 0.0051 16.1 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain T-box PF00907.22 CBY37961.1 - 1.5e-80 269.8 0.8 2e-80 269.4 0.0 1.5 2 0 0 2 2 2 1 T-box Macoilin PF09726.9 CBY37961.1 - 5 5.6 12.1 6.7 5.1 12.1 1.1 1 0 0 1 1 1 0 Macoilin family Plexin_cytopl PF08337.12 CBY37963.1 - 7.6e-120 401.2 1.1 1.3e-119 400.4 1.1 1.4 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CBY37963.1 - 2.8e-14 52.9 2.7 4.5e-09 36.3 0.0 3.4 3 0 0 3 3 3 2 IPT/TIG domain PSI PF01437.25 CBY37963.1 - 1.4e-07 31.9 42.9 7.4e-07 29.6 13.8 3.6 3 0 0 3 3 3 2 Plexin repeat Chordopox_A13L PF05961.11 CBY37963.1 - 0.0069 16.6 0.6 0.022 15.0 0.6 1.9 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.20 CBY37963.1 - 0.037 13.9 0.8 0.071 13.0 0.8 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Sigma_reg_N PF13800.6 CBY37963.1 - 0.25 11.6 1.3 0.7 10.2 1.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal BolA PF01722.18 CBY37964.1 - 2.6e-24 85.3 0.1 3.6e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein Trigger_N PF05697.13 CBY37964.1 - 0.035 14.4 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) Thioredoxin_6 PF13848.6 CBY37965.1 - 1.1e-35 123.2 12.4 6.9e-35 120.6 1.7 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 CBY37965.1 - 3.4e-21 75.2 0.2 1.3e-20 73.3 0.1 2.1 2 0 0 2 2 1 1 Thioredoxin Calsequestrin PF01216.17 CBY37965.1 - 3e-10 39.7 0.9 3e-10 39.7 0.9 2.5 2 1 0 2 2 2 1 Calsequestrin DUF812 PF05667.11 CBY37965.1 - 0.00072 18.6 13.8 0.0012 17.9 13.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) OST3_OST6 PF04756.13 CBY37965.1 - 0.00098 18.6 0.4 0.002 17.6 0.1 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family HOOK PF05622.12 CBY37965.1 - 0.0019 16.5 23.5 0.0028 15.9 23.5 1.1 1 0 0 1 1 1 1 HOOK protein MRP-S27 PF10037.9 CBY37965.1 - 0.0021 17.0 10.2 0.0031 16.5 10.2 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 LMBR1 PF04791.16 CBY37965.1 - 0.0098 14.8 4.6 0.014 14.4 4.6 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein ERM PF00769.19 CBY37965.1 - 0.011 15.6 29.7 0.021 14.6 29.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Thioredoxin_8 PF13905.6 CBY37965.1 - 0.014 15.7 1.9 0.027 14.8 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY37965.1 - 0.02 15.1 0.2 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin-like Borrelia_P83 PF05262.11 CBY37965.1 - 0.035 12.6 15.4 0.048 12.2 15.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MCPsignal PF00015.21 CBY37965.1 - 0.045 13.5 5.9 0.09 12.6 5.9 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Thioredoxin_2 PF13098.6 CBY37965.1 - 0.1 13.1 0.1 0.1 13.1 0.1 3.6 3 2 0 3 3 2 0 Thioredoxin-like domain KxDL PF10241.9 CBY37965.1 - 0.12 12.7 10.1 0.51 10.6 2.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3584 PF12128.8 CBY37965.1 - 0.14 9.7 22.5 0.19 9.2 22.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Questin_oxidase PF14027.6 CBY37965.1 - 0.16 11.4 7.9 0.35 10.4 7.9 1.6 1 1 0 1 1 1 0 Questin oxidase-like COG7 PF10191.9 CBY37965.1 - 0.19 10.0 11.0 0.28 9.4 11.0 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Laminin_II PF06009.12 CBY37965.1 - 0.23 11.4 17.5 0.52 10.3 14.6 2.6 2 1 1 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 CBY37965.1 - 0.25 10.9 8.9 0.43 10.1 8.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SKA2 PF16740.5 CBY37965.1 - 0.26 11.1 16.8 0.063 13.1 6.0 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 AATF-Che1 PF13339.6 CBY37965.1 - 0.27 11.9 13.8 1.4 9.6 13.7 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Flagellin_C PF00700.21 CBY37965.1 - 0.3 11.5 1.0 0.7 10.3 1.0 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Atg14 PF10186.9 CBY37965.1 - 0.36 9.9 11.0 0.78 8.8 11.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4175 PF13779.6 CBY37965.1 - 0.58 8.0 14.7 0.75 7.6 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RmuC PF02646.16 CBY37965.1 - 0.61 9.2 15.0 0.15 11.2 6.2 2.2 1 1 1 2 2 2 0 RmuC family DASH_Duo1 PF08651.10 CBY37965.1 - 1.1 9.0 6.4 0.44 10.4 2.5 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 YkyA PF10368.9 CBY37965.1 - 2.9 7.5 37.7 3.5 7.3 20.7 2.5 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Prominin PF05478.11 CBY37965.1 - 3.4 5.5 8.9 0.19 9.6 2.4 1.7 1 1 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 CBY37965.1 - 4.9 7.6 9.5 3.2 8.2 6.0 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Csm1_B PF18211.1 CBY37965.1 - 5.3 7.0 6.3 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 Csm1 subunit domain B CTD_bind PF04818.13 CBY37966.1 - 3.2e-14 53.5 0.0 7.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 CBY37966.1 - 0.013 15.7 0.8 0.032 14.4 0.8 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MutS_V PF00488.21 CBY37967.1 - 1.3e-11 44.9 0.1 2.6e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBY37967.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.7 1 1 0 1 1 1 1 MutS domain III AAA_16 PF13191.6 CBY37967.1 - 0.03 14.7 0.0 0.075 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CBY37967.1 - 0.1 12.5 1.4 0.86 9.5 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea LXG PF04740.12 CBY37967.1 - 0.22 11.2 1.2 0.45 10.2 0.1 2.0 3 0 0 3 3 3 0 LXG domain of WXG superfamily Peptidase_C2 PF00648.21 CBY37968.1 - 2.3e-72 243.5 0.1 3.3e-72 243.0 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Ank_2 PF12796.7 CBY37969.1 - 1.4e-05 25.5 0.6 0.095 13.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY37969.1 - 8.4e-05 23.1 0.3 5.8 7.6 0.0 4.6 1 1 4 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY37969.1 - 0.0002 21.6 0.4 0.043 14.1 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY37969.1 - 0.011 16.1 0.3 7.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat Vps39_1 PF10366.9 CBY37969.1 - 0.11 12.7 0.6 28 5.0 0.0 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Trypan_PARP PF05887.11 CBY37969.1 - 1.5 8.8 17.7 0.29 11.1 8.4 2.9 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Med3 PF11593.8 CBY37970.1 - 1 8.4 32.2 1.4 8.1 32.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sprouty PF05210.13 CBY37971.1 - 4.9e-16 59.0 16.2 7.4e-16 58.4 16.2 1.2 1 0 0 1 1 1 1 Sprouty protein (Spry) Vinculin PF01044.19 CBY37973.1 - 8.3e-226 752.5 38.8 1.5e-158 529.9 28.3 2.3 1 1 1 2 2 2 2 Vinculin family Peptidase_S21 PF00716.17 CBY37973.1 - 0.059 13.1 0.6 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) PHA_synth_III_E PF09712.10 CBY37973.1 - 0.13 11.4 0.0 0.13 11.4 0.0 3.2 4 0 0 4 4 4 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Collagen_mid PF15984.5 CBY37973.1 - 0.27 11.0 0.0 0.27 11.0 0.0 3.1 4 0 0 4 4 4 0 Bacterial collagen, middle region DUF1798 PF08807.10 CBY37973.1 - 1.1 9.4 5.8 55 4.0 0.1 4.7 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) GIT1_C PF12205.8 CBY37973.1 - 6.4 6.9 21.9 0.96 9.6 0.2 6.5 4 1 2 7 7 7 0 G protein-coupled receptor kinase-interacting protein 1 C term RRM_1 PF00076.22 CBY37974.1 - 2e-29 101.2 5.3 6.2e-12 45.2 0.2 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 CBY37974.1 - 0.0081 16.1 0.1 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain RRM_occluded PF16842.5 CBY37974.1 - 0.023 14.5 0.0 2.4 8.1 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CBY37974.1 - 0.066 13.4 3.2 7.1 6.8 0.1 3.8 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter ParD PF09386.10 CBY37974.1 - 0.14 12.6 0.3 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Antitoxin ParD Keratin_2_head PF16208.5 CBY37974.1 - 0.85 9.7 21.5 1.7 8.8 21.5 1.5 1 0 0 1 1 1 0 Keratin type II head zf-C2H2 PF00096.26 CBY37976.1 - 0.0003 21.1 0.4 0.0003 21.1 0.4 6.1 9 0 0 9 9 9 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY37976.1 - 0.00075 20.1 0.2 0.00075 20.1 0.2 6.1 6 0 0 6 6 6 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY37976.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger HigB-like_toxin PF05015.13 CBY37976.1 - 0.021 15.2 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB DUF1924 PF09086.11 CBY37976.1 - 0.048 14.0 0.4 0.22 11.9 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) zf-C2HE PF16278.5 CBY37976.1 - 0.072 13.6 6.6 3.4 8.2 0.0 3.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CBY37976.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY37976.1 - 0.32 11.4 0.1 0.32 11.4 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 CBY37976.1 - 0.6 10.2 10.4 0.93 9.6 4.9 3.5 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like Aldo_ket_red PF00248.21 CBY37977.1 - 8.4e-41 140.1 0.0 1.8e-40 139.0 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family TIR PF01582.20 CBY37977.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 TIR domain Dynamin_N PF00350.23 CBY37978.1 - 5.9e-31 107.8 0.0 1.6e-30 106.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 CBY37978.1 - 1.3e-07 31.1 1.9 9e-07 28.4 0.7 2.6 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 CBY37978.1 - 2e-05 24.6 0.0 0.00023 21.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY37978.1 - 0.015 15.7 0.2 0.086 13.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 CBY37978.1 - 0.034 14.3 1.5 0.79 10.0 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 CBY37978.1 - 0.044 13.6 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Arrestin_N PF00339.29 CBY37979.1 - 1.8e-35 122.1 0.0 3.2e-33 114.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CBY37979.1 - 3.9e-26 92.1 0.2 1.1e-25 90.6 0.4 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Adeno_GP19K PF04881.13 CBY37979.1 - 0.095 12.7 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Adenovirus GP19K DUF2393 PF09624.10 CBY37979.1 - 0.13 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) ECH_1 PF00378.20 CBY37980.1 - 8e-30 104.0 0.0 9.8e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY37980.1 - 7e-15 55.4 0.0 9.7e-15 54.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4586 PF15239.6 CBY37981.1 - 4.2e-52 178.2 3.7 4.7e-52 178.1 3.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) APG12 PF04110.13 CBY37982.1 - 1.8e-28 98.8 0.0 2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CBY37982.1 - 6.2e-05 23.1 0.0 6.6e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like VPS9 PF02204.18 CBY37983.1 - 4.7e-17 62.1 0.0 1.2e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-A20 PF01754.16 CBY37983.1 - 1.4e-09 37.7 7.1 1.4e-09 37.7 7.1 2.0 2 0 0 2 2 2 1 A20-like zinc finger DUF5601 PF18151.1 CBY37983.1 - 0.0072 16.6 2.4 0.018 15.3 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) SGTA_dimer PF16546.5 CBY37983.1 - 0.014 15.2 0.1 0.18 11.6 0.0 2.6 2 0 0 2 2 2 0 Homodimerisation domain of SGTA PWI PF01480.17 CBY37983.1 - 0.066 13.5 0.6 0.41 11.0 0.1 2.5 3 0 0 3 3 3 0 PWI domain WD40 PF00400.32 CBY37984.1 - 1.1e-40 136.8 17.8 1.5e-07 32.0 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY37984.1 - 1.1e-15 57.6 5.1 0.0028 17.9 0.0 6.3 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY37984.1 - 8.1e-09 34.9 9.6 0.26 10.2 0.0 5.1 1 1 3 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY37984.1 - 4.2e-07 28.8 0.1 0.045 12.3 0.1 3.0 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 CBY37984.1 - 1.4e-05 24.0 0.3 0.0075 15.0 0.3 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CBY37984.1 - 1.9e-05 24.7 0.3 0.00025 21.0 0.0 2.6 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBY37984.1 - 0.00038 19.9 0.8 0.017 14.5 0.1 2.7 3 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 CBY37984.1 - 0.013 15.4 1.8 10 6.2 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 CBY37984.1 - 0.018 13.4 0.0 0.036 12.4 0.0 1.5 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PHTB1_N PF14727.6 CBY37984.1 - 0.046 13.1 0.0 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 PTHB1 N-terminus CDC45 PF02724.14 CBY37985.1 - 1.1e-83 281.6 0.2 4.5e-51 173.9 1.3 2.0 1 1 1 2 2 2 2 CDC45-like protein HDC PF02329.16 CBY37985.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine carboxylase PI chain CDC45 PF02724.14 CBY37986.1 - 4e-22 78.3 0.1 4.7e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Mesd PF10185.9 CBY37986.1 - 0.028 14.3 0.0 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor Pkinase PF00069.25 CBY37987.1 - 1.6e-58 198.2 0.1 1.9e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY37987.1 - 6.1e-26 91.3 0.1 7.1e-26 91.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY37987.1 - 4.1e-06 26.3 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY37987.1 - 7.9e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY37987.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY37987.1 - 0.00082 19.0 0.2 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY37987.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY37987.1 - 0.0064 15.5 0.2 0.012 14.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 CBY37987.1 - 0.0067 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 CBY37987.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CBY37987.1 - 0.024 14.3 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5446 PF17522.2 CBY37987.1 - 0.078 13.2 0.3 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Pox_ser-thr_kin PF05445.11 CBY37987.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IQ PF00612.27 CBY37988.1 - 0.00037 20.0 0.1 0.0011 18.6 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Rimk_N PF18030.1 CBY37988.1 - 0.061 13.7 3.5 0.18 12.2 0.1 2.9 3 0 0 3 3 3 0 RimK PreATP-grasp domain DUF3584 PF12128.8 CBY37988.1 - 0.24 8.9 30.8 0.31 8.5 30.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WDCP PF15390.6 CBY37988.1 - 3.7 5.8 13.9 5.6 5.2 13.9 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Gaa1 PF04114.14 CBY37989.1 - 5.6e-53 180.7 0.1 8.1e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component B56 PF01603.20 CBY37991.1 - 4.4e-128 427.8 5.0 5.1e-128 427.6 5.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY37991.1 - 0.0006 19.8 1.1 0.067 13.1 0.2 2.4 1 1 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Pepdidase_M14_N PF18027.1 CBY37993.1 - 3.6e-18 65.9 0.3 1e-17 64.4 0.3 1.8 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 CBY37993.1 - 4.9e-15 56.1 2.1 3.4e-14 53.3 1.1 2.9 1 1 0 1 1 1 1 Zinc carboxypeptidase EGF PF00008.27 CBY37994.1 - 3.3e-13 49.7 47.8 1.8e-06 28.1 2.7 4.7 3 1 2 5 5 5 3 EGF-like domain EGF_CA PF07645.15 CBY37994.1 - 1e-12 48.0 26.7 6.2e-09 35.9 6.3 4.4 2 2 2 4 4 4 2 Calcium-binding EGF domain EGF_2 PF07974.13 CBY37994.1 - 8.1e-12 45.3 58.6 0.00019 21.7 10.1 4.2 4 0 0 4 4 4 4 EGF-like domain hEGF PF12661.7 CBY37994.1 - 8.6e-07 29.4 54.9 0.0004 20.9 8.3 5.9 6 0 0 6 6 6 3 Human growth factor-like EGF EGF_3 PF12947.7 CBY37994.1 - 2.6e-06 27.5 38.7 0.00032 20.8 2.0 5.5 2 2 3 5 5 5 3 EGF domain Laminin_EGF PF00053.24 CBY37994.1 - 2.3 8.4 45.1 1.9 8.7 5.9 4.4 2 1 2 4 4 4 0 Laminin EGF domain HATPase_c_3 PF13589.6 CBY37996.1 - 4.9e-17 62.0 0.1 6.5e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY37996.1 - 4.2e-09 36.9 0.0 5.6e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCDC50_N PF15295.6 CBY37997.1 - 7.3e-35 119.9 40.7 1.7e-34 118.7 14.6 4.8 2 1 3 5 5 5 3 Coiled-coil domain-containing protein 50 N-terminus AMP-binding PF00501.28 CBY37998.1 - 1.4e-86 290.8 0.0 1.7e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY37998.1 - 2.7e-19 69.9 0.5 5.4e-19 69.0 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CBY37998.1 - 4.1e-16 58.6 3.5 1.5e-15 56.9 2.9 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus URO-D PF01208.17 CBY37999.1 - 6.1e-126 420.2 0.0 6.8e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AMP-binding PF00501.28 CBY38000.1 - 8.7e-93 311.2 0.0 1e-92 311.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CBY38000.1 - 7.2e-17 61.1 0.7 1.7e-16 59.9 0.2 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Ank_2 PF12796.7 CBY38001.1 - 1.4e-12 48.0 0.2 4.1e-06 27.3 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBY38001.1 - 1.8e-07 31.3 0.8 2.5 8.7 0.0 5.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 CBY38001.1 - 5.9e-05 23.5 0.2 0.0019 18.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY38001.1 - 0.00027 21.1 0.6 0.012 16.1 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CBY38001.1 - 0.0041 17.4 0.1 0.022 15.1 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TMIE PF16038.5 CBY38002.1 - 0.031 14.1 3.0 0.049 13.5 3.0 1.3 1 0 0 1 1 1 0 TMIE protein MLANA PF14991.6 CBY38002.1 - 0.049 13.9 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein melan-A GAPT PF11770.8 CBY38002.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) WBP-1 PF11669.8 CBY38002.1 - 0.14 12.8 1.1 0.35 11.5 1.1 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 PMSR PF01625.21 CBY38003.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase Sec63 PF02889.16 CBY38004.1 - 5.5e-88 294.5 0.1 3e-61 206.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBY38004.1 - 2.7e-25 89.1 0.0 1.7e-24 86.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY38004.1 - 4.6e-11 43.0 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBY38004.1 - 5.9e-08 33.0 0.0 3.5e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CBY38004.1 - 0.002 18.4 0.1 0.024 14.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain Acyl_transf_2 PF02273.15 CBY38004.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase AAA_19 PF13245.6 CBY38004.1 - 0.088 13.1 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY38004.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain Tim44 PF04280.15 CBY38005.1 - 1.3e-36 126.0 0.2 1.3e-36 126.0 0.2 1.8 2 0 0 2 2 2 1 Tim44-like domain OmpH PF03938.14 CBY38005.1 - 0.12 12.7 11.6 0.04 14.2 7.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2408 PF10303.9 CBY38005.1 - 0.17 12.5 4.7 0.16 12.5 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Bacillus_HBL PF05791.11 CBY38005.1 - 0.42 10.4 8.4 0.1 12.4 4.8 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1690 PF07956.11 CBY38005.1 - 0.55 10.6 7.4 1.3 9.5 6.5 2.0 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF4882 PF16223.5 CBY38007.1 - 0.12 11.6 0.2 0.14 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) N6-adenineMlase PF10237.9 CBY38008.1 - 1.6e-38 132.0 0.3 2.4e-38 131.4 0.3 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 CBY38008.1 - 0.18 11.4 0.5 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 YPEB PF14620.6 CBY38009.1 - 0.14 11.5 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 YpeB sporulation YppG PF14179.6 CBY38009.1 - 6 7.6 17.8 28 5.5 0.3 3.7 3 1 0 3 3 3 0 YppG-like protein PTPS PF01242.19 CBY38010.1 - 2.2e-30 105.2 0.2 2.4e-30 105.0 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Macoilin PF09726.9 CBY38011.1 - 0.0044 15.7 10.1 0.0054 15.4 10.1 1.0 1 0 0 1 1 1 1 Macoilin family FAM184 PF15665.5 CBY38011.1 - 0.32 10.7 6.8 0.13 12.1 3.9 1.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Tmem26 PF09772.9 CBY38012.1 - 7.4e-28 97.7 0.3 8.5e-28 97.5 0.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 26 PgaD PF13994.6 CBY38012.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein VraX PF17412.2 CBY38012.1 - 0.098 12.3 0.2 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function DUF2076 PF09849.9 CBY38013.1 - 0.12 12.5 1.5 0.13 12.3 1.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RhoGAP PF00620.27 CBY38014.1 - 1.2e-30 106.3 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Nsp1_C PF05064.13 CBY38015.1 - 1.7e-26 92.3 6.7 2.9e-26 91.6 6.7 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG2 PF15967.5 CBY38015.1 - 0.00087 18.0 33.6 0.0011 17.6 33.6 1.1 1 0 0 1 1 1 1 Nucleoporin FG repeated region Laminin_I PF06008.14 CBY38015.1 - 0.001 18.8 5.2 0.001 18.8 5.2 1.7 1 1 1 2 2 2 1 Laminin Domain I DUF812 PF05667.11 CBY38015.1 - 0.0055 15.7 3.2 0.0066 15.4 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1465 PF07323.12 CBY38015.1 - 0.032 14.1 1.4 0.05 13.4 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Fib_alpha PF08702.10 CBY38015.1 - 0.041 14.1 2.9 0.18 12.0 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.6 CBY38015.1 - 0.074 13.3 1.2 0.074 13.3 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Pdase_M17_N2 PF18295.1 CBY38015.1 - 0.11 12.7 1.8 1 9.6 0.1 2.6 2 1 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 DUF2746 PF10874.8 CBY38015.1 - 0.14 12.6 0.2 0.32 11.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) DUF2048 PF09752.9 CBY38015.1 - 0.15 11.1 5.8 0.07 12.2 3.0 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Ead_Ea22 PF13935.6 CBY38015.1 - 0.24 12.1 4.6 0.52 11.0 4.6 1.6 1 1 0 1 1 1 0 Ead/Ea22-like protein APG6_N PF17675.1 CBY38015.1 - 0.42 11.1 6.8 0.51 10.9 5.5 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region SYCE1 PF15233.6 CBY38015.1 - 0.51 10.4 7.1 0.14 12.3 4.1 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Seryl_tRNA_N PF02403.22 CBY38015.1 - 0.91 9.8 8.2 1.3 9.2 1.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 CBY38015.1 - 1.3 9.6 7.4 11 6.6 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 CBY38015.1 - 2.3 8.7 7.8 0.42 11.1 3.0 2.1 2 1 1 3 3 2 0 Snapin/Pallidin DUF1664 PF07889.12 CBY38015.1 - 3.1 7.8 6.2 8.2 6.5 1.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CBY38015.1 - 5.3 7.2 11.5 46 4.1 11.5 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rieske PF00355.26 CBY38016.1 - 0.00086 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LETM1 PF07766.13 CBY38017.1 - 1.3e-16 60.7 0.0 8.5e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 LETM1-like protein G-patch PF01585.23 CBY38018.1 - 6.2e-13 48.4 1.6 1.4e-12 47.3 1.6 1.7 1 0 0 1 1 1 1 G-patch domain CEP76-C2 PF15627.6 CBY38019.1 - 5.3e-39 133.3 0.2 9.9e-39 132.4 0.2 1.4 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.30 CBY38019.1 - 0.045 14.0 0.1 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 C2 domain PG_binding_1 PF01471.18 CBY38020.1 - 1.7e-06 28.2 0.1 8.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain MRC1 PF09444.10 CBY38020.1 - 0.17 12.4 3.4 0.3 11.6 3.4 1.3 1 0 0 1 1 1 0 MRC1-like domain Guanylate_cyc PF00211.20 CBY38021.1 - 4.5e-101 336.1 0.3 1.8e-50 171.1 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AC_N PF16214.5 CBY38021.1 - 3e-18 66.2 1.8 3.6e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 Adenylyl cyclase N-terminal extracellular and transmembrane region AA_permease PF00324.21 CBY38021.1 - 0.00023 19.9 1.6 0.00051 18.8 1.6 1.5 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.16 CBY38021.1 - 0.76 10.2 4.9 3.7 7.9 0.0 3.5 3 0 0 3 3 3 0 Divalent cation transporter DUF4383 PF14325.6 CBY38021.1 - 0.81 10.0 0.0 0.81 10.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) zf-RING_2 PF13639.6 CBY38023.1 - 1.9e-05 24.9 8.2 3.9e-05 23.9 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY38023.1 - 8.6e-05 22.5 8.2 0.00016 21.6 8.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY38023.1 - 0.00031 20.5 11.1 0.0012 18.6 11.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY38023.1 - 0.00063 19.6 5.2 0.0011 18.8 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY38023.1 - 0.00091 19.0 12.2 0.0055 16.5 12.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY38023.1 - 0.0018 18.2 12.0 0.0061 16.5 12.3 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY38023.1 - 0.0055 16.5 11.2 0.016 15.1 11.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Enkurin PF13864.6 CBY38023.1 - 0.0059 17.0 5.5 0.0059 17.0 5.5 2.7 1 1 2 3 3 3 1 Calmodulin-binding Exonuc_VII_L PF02601.15 CBY38023.1 - 0.0065 16.1 5.3 0.0089 15.6 5.3 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit IBR PF01485.21 CBY38023.1 - 0.038 14.2 7.0 0.076 13.3 7.0 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Fusion_gly PF00523.18 CBY38023.1 - 0.045 12.0 2.9 0.063 11.5 2.9 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Golgin_A5 PF09787.9 CBY38023.1 - 0.052 13.0 16.9 0.073 12.5 16.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SUKH-3 PF14433.6 CBY38023.1 - 0.062 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 SUKH-3 immunity protein HMMR_N PF15905.5 CBY38023.1 - 0.065 12.7 14.1 0.086 12.3 14.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Colicin PF01024.19 CBY38023.1 - 0.093 12.6 2.4 0.14 12.0 2.4 1.2 1 0 0 1 1 1 0 Colicin pore forming domain Macoilin PF09726.9 CBY38023.1 - 0.11 11.0 6.8 0.11 11.0 6.8 1.1 1 0 0 1 1 1 0 Macoilin family PIN_8 PF18476.1 CBY38023.1 - 0.11 12.3 7.8 0.18 11.6 7.8 1.3 1 0 0 1 1 1 0 PIN like domain Matrilin_ccoil PF10393.9 CBY38023.1 - 0.15 12.0 2.4 0.21 11.4 0.8 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-RING_4 PF14570.6 CBY38023.1 - 0.16 11.8 7.4 0.4 10.5 7.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY38023.1 - 0.3 11.0 13.0 0.13 12.1 5.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY38023.1 - 0.36 10.7 6.0 0.66 9.9 6.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein YojJ PF10372.9 CBY38023.1 - 0.4 10.8 5.0 1.1 9.4 0.9 2.4 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Sulfatase_C PF14707.6 CBY38023.1 - 0.57 10.9 6.4 0.66 10.7 0.6 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase TrwC PF08751.11 CBY38023.1 - 0.88 9.0 6.0 0.22 11.0 1.6 1.8 1 1 1 2 2 2 0 TrwC relaxase V_ATPase_I PF01496.19 CBY38023.1 - 0.88 7.4 8.3 1 7.2 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2703 PF10865.8 CBY38023.1 - 0.9 9.7 7.9 0.53 10.5 5.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Tweety PF04906.13 CBY38023.1 - 1.1 7.9 3.4 1.5 7.4 3.4 1.2 1 0 0 1 1 1 0 Tweety Spc7 PF08317.11 CBY38023.1 - 1.2 8.0 15.8 1.8 7.4 15.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C3HC4_4 PF15227.6 CBY38023.1 - 1.5 9.0 8.2 13 6.0 8.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING HrpB7 PF09486.10 CBY38023.1 - 1.9 8.9 14.2 27 5.1 14.2 2.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 CBY38023.1 - 4.1 7.5 9.3 9.6 6.3 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 CBY38023.1 - 5.1 7.5 12.3 11 6.4 11.6 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Baculo_IE-1 PF05290.11 CBY38023.1 - 8.6 6.3 12.0 66 3.4 12.0 2.1 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) CitMHS PF03600.16 CBY38024.1 - 0.0074 15.5 18.8 0.15 11.2 18.7 2.2 1 1 0 1 1 1 1 Citrate transporter VIT1 PF01988.19 CBY38024.1 - 3.6 7.4 5.9 6 6.7 4.8 2.0 2 0 0 2 2 2 0 VIT family EGF PF00008.27 CBY38025.1 - 1.8e-21 76.1 56.9 3.7e-07 30.3 5.9 5.8 6 0 0 6 6 6 4 EGF-like domain hEGF PF12661.7 CBY38025.1 - 5.3e-10 39.5 46.3 0.00022 21.7 2.7 5.5 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_3 PF12947.7 CBY38025.1 - 7.4e-08 32.5 39.8 0.00056 20.1 5.3 5.3 4 1 1 5 5 5 3 EGF domain cEGF PF12662.7 CBY38025.1 - 0.0011 18.8 30.0 0.12 12.3 5.2 4.1 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_2 PF07974.13 CBY38025.1 - 0.13 12.6 59.9 0.15 12.5 10.4 5.4 5 0 0 5 5 5 0 EGF-like domain FXa_inhibition PF14670.6 CBY38025.1 - 1.1 9.6 49.1 1.9 8.8 9.2 5.6 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site SOG2 PF10428.9 CBY38025.1 - 4.1 6.5 40.4 5.8 6.0 40.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_UBOX PF13445.6 CBY38026.1 - 8.4e-06 25.7 5.1 8.4e-06 25.7 5.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY38026.1 - 1.4e-05 25.3 13.0 3.9e-05 23.9 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY38026.1 - 0.00078 19.3 10.3 0.00078 19.3 10.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY38026.1 - 0.0015 18.4 17.4 0.0028 17.6 11.1 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY38026.1 - 0.0043 16.9 17.1 0.013 15.4 11.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY38026.1 - 0.0048 16.7 16.8 0.0072 16.2 11.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY38026.1 - 0.0056 16.5 5.7 0.0056 16.5 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CBY38026.1 - 0.0061 16.2 4.0 0.0089 15.6 4.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Enkurin PF13864.6 CBY38026.1 - 0.012 16.0 5.5 0.012 16.0 5.5 2.6 1 1 1 2 2 2 0 Calmodulin-binding zf-RING_4 PF14570.6 CBY38026.1 - 0.018 14.9 13.2 0.17 11.7 7.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY38026.1 - 0.075 12.9 19.0 4.4 7.2 0.4 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Golgin_A5 PF09787.9 CBY38026.1 - 0.078 12.4 16.3 0.12 11.8 16.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 IBR PF01485.21 CBY38026.1 - 0.091 13.0 11.4 0.14 12.4 7.0 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 CBY38026.1 - 0.1 12.7 9.2 0.57 10.2 3.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Fusion_gly PF00523.18 CBY38026.1 - 0.1 10.8 2.9 0.14 10.4 2.9 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 SUKH-3 PF14433.6 CBY38026.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 SUKH-3 immunity protein HMMR_N PF15905.5 CBY38026.1 - 0.16 11.4 14.1 0.23 10.9 14.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Colicin PF01024.19 CBY38026.1 - 0.19 11.6 2.3 0.3 10.9 2.3 1.2 1 0 0 1 1 1 0 Colicin pore forming domain zf-C2H2_jaz PF12171.8 CBY38026.1 - 0.48 10.8 5.7 1.1 9.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YojJ PF10372.9 CBY38026.1 - 0.55 10.4 3.9 1.5 9.0 0.6 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FYVE PF01363.21 CBY38026.1 - 0.69 10.1 9.1 1.3 9.2 3.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 CBY38026.1 - 0.79 9.9 9.5 4.2 7.6 6.9 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sulfatase_C PF14707.6 CBY38026.1 - 0.81 10.4 5.3 1.3 9.8 0.7 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF2703 PF10865.8 CBY38026.1 - 0.88 9.8 6.7 0.7 10.1 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) V_ATPase_I PF01496.19 CBY38026.1 - 2.1 6.2 8.3 2.5 5.9 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CBY38026.1 - 2.7 6.8 15.7 4.1 6.2 15.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBY38026.1 - 3.2 8.1 13.5 45 4.4 13.4 2.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Zn-C2H2_12 PF18112.1 CBY38026.1 - 3.3 8.2 9.0 12 6.5 0.5 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain CENP-H PF05837.12 CBY38026.1 - 7.3 7.0 11.4 18 5.8 11.2 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) RT_RNaseH_2 PF17919.1 CBY38027.1 - 1e-24 86.4 0.0 1.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY38027.1 - 7.5e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY38027.1 - 0.077 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain 7tm_7 PF08395.12 CBY38027.1 - 0.12 11.5 0.0 0.8 8.8 0.0 1.9 2 0 0 2 2 2 0 7tm Chemosensory receptor Spem1 PF15670.5 CBY38028.1 - 0.06 12.9 2.7 0.17 11.4 2.7 1.7 1 0 0 1 1 1 0 Spermatid maturation protein 1 CENP-Q PF13094.6 CBY38028.1 - 6.4 7.0 15.0 1.5 9.0 0.3 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Sulfatase PF00884.23 CBY38029.1 - 1.5e-42 146.0 0.3 2.2e-42 145.5 0.3 1.2 1 0 0 1 1 1 1 Sulfatase UIM PF02809.20 CBY38030.1 - 0.0051 16.6 0.8 0.0051 16.6 0.8 2.0 2 0 0 2 2 2 1 Ubiquitin interaction motif UBX PF00789.20 CBY38030.1 - 0.0087 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 UBX domain Topoisom_bac PF01131.20 CBY38031.1 - 8e-103 344.6 0.0 1e-102 344.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CBY38031.1 - 2.4e-22 78.8 19.3 2.6e-14 53.0 2.5 3.3 4 0 0 4 4 4 2 GRF zinc finger Toprim PF01751.22 CBY38031.1 - 4.2e-17 62.2 0.0 8.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 CBY38031.1 - 9.3e-05 22.1 6.3 9.3e-05 22.1 6.3 3.6 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CBY38031.1 - 0.31 11.2 4.9 1.2 9.4 4.9 2.1 1 0 0 1 1 1 0 Zinc knuckle NAP PF00956.18 CBY38032.1 - 2.2e-14 53.3 4.4 3e-14 52.8 4.4 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) AAR2 PF05282.11 CBY38032.1 - 0.029 13.8 0.7 0.04 13.3 0.3 1.4 1 1 0 1 1 1 0 AAR2 protein FATC PF02260.20 CBY38033.1 - 6.1e-08 32.3 0.0 8.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 FATC domain PI3_PI4_kinase PF00454.27 CBY38034.1 - 5.1e-40 137.9 0.0 2.8e-39 135.4 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase HTH_micro PF17007.5 CBY38035.1 - 0.027 13.3 0.4 0.038 12.8 0.4 1.1 1 0 0 1 1 1 0 HTH-like PDZ_2 PF13180.6 CBY38035.1 - 0.055 13.8 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 PDZ domain Phospholip_A2_1 PF00068.19 CBY38036.1 - 2.8e-19 69.6 11.7 4.5e-19 69.0 11.7 1.3 1 0 0 1 1 1 1 Phospholipase A2 VWA_3 PF13768.6 CBY38037.1 - 3.3e-10 40.1 0.0 6.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CBY38037.1 - 7.7e-07 29.5 0.0 2.6e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY38037.1 - 0.15 12.7 0.0 0.57 10.8 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4094 PF13334.6 CBY38038.1 - 0.012 16.0 13.3 0.012 16.0 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.9 CBY38038.1 - 0.063 13.3 36.9 0.16 12.0 16.0 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CBY38038.1 - 0.13 12.3 10.7 0.62 10.1 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 CBY38038.1 - 0.23 11.8 19.4 0.096 13.0 5.0 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) CLZ PF16526.5 CBY38038.1 - 0.39 11.1 17.4 1.3 9.4 0.8 3.9 3 2 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 CBY38038.1 - 2.4 8.0 24.8 3.1 7.6 8.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF724) ATPase PF06745.13 CBY38038.1 - 4.2 6.6 8.7 2 7.7 4.7 2.3 1 1 1 2 2 2 0 KaiC CorA PF01544.18 CBY38038.1 - 8.3 5.6 14.1 1.4 8.1 3.9 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Glyco_transf_64 PF09258.10 CBY38040.1 - 0.0019 17.5 0.8 0.53 9.5 0.1 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 64 domain Ribosomal_L14e PF01929.17 CBY38040.1 - 0.029 14.9 0.2 0.082 13.4 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L14 RNase_P_p30 PF01876.16 CBY38042.1 - 4.5e-40 137.4 0.0 5.4e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M17 PF00883.21 CBY38043.1 - 2.6e-63 214.2 0.1 3.8e-63 213.7 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain GIY-YIG PF01541.24 CBY38044.1 - 1.8e-12 47.4 0.0 3.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 CBY38044.1 - 2.4e-06 27.7 2.1 4.9e-06 26.7 2.1 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CBY38044.1 - 1.4e-05 25.2 4.0 2.9e-05 24.2 4.0 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.29 CBY38044.1 - 0.02 14.8 6.3 0.05 13.5 6.3 1.8 1 0 0 1 1 1 0 PHD-finger Rubredoxin PF00301.20 CBY38044.1 - 0.084 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Rubredoxin FANCL_C PF11793.8 CBY38044.1 - 0.15 12.3 4.9 0.4 10.9 4.9 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain T5orf172 PF10544.9 CBY38044.1 - 0.23 12.0 1.0 0.52 10.9 0.3 2.1 2 1 0 2 2 2 0 T5orf172 domain C1_2 PF03107.16 CBY38044.1 - 1.5 9.2 6.5 0.37 11.1 2.0 2.2 2 0 0 2 2 2 0 C1 domain IFRD PF05004.13 CBY38045.1 - 0.0044 16.2 0.1 0.0048 16.0 0.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Sec7_N PF12783.7 CBY38045.1 - 0.031 14.2 0.2 0.059 13.3 0.3 1.4 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1415 PF07209.12 CBY38045.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) DUF5420 PF17457.2 CBY38045.1 - 0.16 11.8 0.0 0.19 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5420) CBM_14 PF01607.24 CBY38046.1 - 3.4e-12 46.3 4.7 4.3e-12 46.0 4.1 1.6 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Ig_3 PF13927.6 CBY38047.1 - 7.1e-32 109.9 9.7 1.6e-07 31.9 0.0 8.8 8 1 0 8 8 8 5 Immunoglobulin domain Ig_2 PF13895.6 CBY38047.1 - 1.1e-30 105.7 1.5 4.1e-10 39.8 0.0 7.8 8 0 0 8 8 8 3 Immunoglobulin domain ig PF00047.25 CBY38047.1 - 1.4e-23 82.8 17.2 5.8e-05 23.2 0.3 10.2 9 3 1 10 10 10 4 Immunoglobulin domain I-set PF07679.16 CBY38047.1 - 1.1e-20 73.5 7.4 0.00014 21.9 0.0 9.3 8 3 0 8 8 8 3 Immunoglobulin I-set domain Laminin_G_2 PF02210.24 CBY38047.1 - 5.4e-14 52.8 0.1 1.3e-13 51.6 0.1 1.7 1 0 0 1 1 1 1 Laminin G domain Ig_5 PF16681.5 CBY38047.1 - 1.3e-13 51.1 8.9 0.0012 19.2 0.2 5.6 6 1 1 7 7 7 3 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY38047.1 - 3.7e-13 49.5 6.0 0.0013 19.0 0.2 5.3 6 0 0 6 6 5 3 T-cell surface glycoprotein CD3 delta chain V-set PF07686.17 CBY38047.1 - 6.2e-13 48.9 3.6 8e-06 26.0 0.1 6.6 6 1 1 7 7 7 2 Immunoglobulin V-set domain Laminin_G_1 PF00054.23 CBY38047.1 - 7.6e-08 32.6 0.1 4.6e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 Laminin G domain Ig_6 PF18452.1 CBY38047.1 - 1e-07 31.4 0.2 0.73 9.4 0.0 4.6 5 0 0 5 5 5 3 Immunoglobulin domain Izumo-Ig PF16706.5 CBY38047.1 - 0.00043 20.3 0.0 1.2 9.2 0.0 4.4 4 0 0 4 4 4 1 Izumo-like Immunoglobulin domain CBM_15 PF03426.14 CBY38047.1 - 0.021 14.4 0.4 2.8 7.5 0.1 3.3 4 0 0 4 4 4 0 Carbohydrate binding domain (family 15) C2-set PF05790.15 CBY38047.1 - 0.13 12.5 0.0 3.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin C2-set domain DUF3581 PF12119.8 CBY38047.1 - 0.13 11.7 0.0 5.1 6.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3581) Laminin_B PF00052.18 CBY38048.1 - 2.5e-54 182.8 0.0 5.9e-25 87.7 0.1 3.4 3 0 0 3 3 3 3 Laminin B (Domain IV) Ig_3 PF13927.6 CBY38048.1 - 6.7e-30 103.5 5.2 2e-16 60.4 0.7 3.3 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY38048.1 - 4.4e-26 90.8 0.0 1.2e-15 57.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin I-set domain VWA PF00092.28 CBY38048.1 - 7.2e-21 75.2 1.3 1.2e-20 74.5 1.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ldl_recept_a PF00057.18 CBY38048.1 - 5.7e-20 71.2 52.2 4.8e-10 39.5 12.8 6.9 7 0 0 7 7 3 3 Low-density lipoprotein receptor domain class A Ig_2 PF13895.6 CBY38048.1 - 9.7e-20 70.7 0.9 6.8e-09 35.9 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin domain ig PF00047.25 CBY38048.1 - 6.2e-16 58.4 0.1 3.4e-09 36.7 0.1 2.8 2 0 0 2 2 2 2 Immunoglobulin domain V-set PF07686.17 CBY38048.1 - 5.8e-10 39.3 7.2 0.027 14.6 0.5 5.1 4 2 1 5 5 5 3 Immunoglobulin V-set domain Laminin_EGF PF00053.24 CBY38048.1 - 5.8e-09 36.0 44.7 8.3e-06 25.8 7.3 9.8 8 4 1 10 10 7 5 Laminin EGF domain VWA_2 PF13519.6 CBY38048.1 - 6.1e-07 30.0 0.4 1.5e-06 28.8 0.4 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain C2-set_2 PF08205.12 CBY38048.1 - 0.0051 16.8 4.5 0.78 9.9 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain LRR_9 PF14580.6 CBY38052.1 - 1e-12 47.9 0.3 2.1e-12 46.9 0.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBY38052.1 - 8.9e-12 44.6 8.6 1.7e-07 30.9 2.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat DNA_pol_A_exo1 PF01612.20 CBY38052.1 - 3.3e-11 43.2 0.0 7.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease LRR_4 PF12799.7 CBY38052.1 - 1.3e-09 38.2 10.4 1.3e-05 25.5 0.5 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) PetG PF02529.15 CBY38052.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF1002 PF06207.11 CBY38052.1 - 0.74 9.3 3.6 1.6 8.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) LRR_1 PF00560.33 CBY38052.1 - 0.81 10.5 9.5 22 6.1 0.0 4.8 3 1 1 4 4 4 0 Leucine Rich Repeat Gag_p15 PF08723.10 CBY38054.1 - 0.087 13.0 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Gag protein p15 Jacalin PF01419.17 CBY38055.1 - 0.0019 18.2 0.0 0.0039 17.1 0.0 1.6 1 1 0 1 1 1 1 Jacalin-like lectin domain Bestrophin PF01062.21 CBY38056.1 - 0.08 12.3 1.1 0.087 12.2 1.1 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Protocadherin PF08374.11 CBY38057.1 - 3.3e-05 24.0 1.8 4.1e-05 23.7 1.8 1.1 1 0 0 1 1 1 1 Protocadherin ArgoN PF16486.5 CBY38058.1 - 0.00093 19.8 0.0 0.002 18.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY38058.1 - 0.13 12.0 0.1 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Argonaute linker 1 domain DUF5320 PF17253.2 CBY38058.1 - 0.33 12.0 1.6 1.4 10.0 1.6 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5320) zf-RING_5 PF14634.6 CBY38060.1 - 6.4e-06 26.0 12.2 5.6e-05 23.0 7.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY38060.1 - 1.1e-05 25.7 7.8 1.1e-05 25.7 7.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY38060.1 - 1.4e-05 25.1 4.9 1.4e-05 25.1 4.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY38060.1 - 0.0002 21.1 16.1 0.0005 19.9 10.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY38060.1 - 0.00066 19.5 17.2 0.014 15.3 11.1 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HMMR_N PF15905.5 CBY38060.1 - 0.0034 16.9 10.0 0.006 16.1 10.0 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal TolA_bind_tri PF16331.5 CBY38060.1 - 0.0039 17.2 1.2 0.0039 17.2 1.2 2.0 1 1 0 1 1 1 1 TolA binding protein trimerisation zf-C3HC4_2 PF13923.6 CBY38060.1 - 0.0049 16.7 18.1 0.0086 15.9 11.8 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Spc7 PF08317.11 CBY38060.1 - 0.0052 15.7 10.8 0.0087 15.0 10.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Vhr1 PF04001.13 CBY38060.1 - 0.0069 16.6 0.3 0.019 15.3 0.3 1.7 1 0 0 1 1 1 1 Transcription factor Vhr1 Exonuc_VII_L PF02601.15 CBY38060.1 - 0.01 15.5 2.5 0.01 15.5 2.5 1.8 2 0 0 2 2 2 1 Exonuclease VII, large subunit zf-RING_4 PF14570.6 CBY38060.1 - 0.011 15.5 12.5 0.47 10.3 7.9 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 CBY38060.1 - 0.011 15.6 5.5 0.011 15.6 5.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 CBY38060.1 - 0.018 15.0 9.5 0.46 10.6 3.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Cluap1 PF10234.9 CBY38060.1 - 0.03 13.7 9.6 0.058 12.8 9.6 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Nup54 PF13874.6 CBY38060.1 - 0.032 14.3 4.3 0.084 13.0 4.3 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Anillin_N PF16018.5 CBY38060.1 - 0.041 14.5 0.0 0.26 11.9 0.0 2.4 1 1 1 2 2 1 0 Anillin N-terminus Prok-RING_4 PF14447.6 CBY38060.1 - 0.044 13.6 16.6 0.1 12.5 4.4 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 CALCOCO1 PF07888.11 CBY38060.1 - 0.055 12.3 13.1 0.081 11.8 13.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 CBY38060.1 - 0.07 13.2 11.2 0.14 12.2 11.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.15 CBY38060.1 - 0.075 12.9 4.3 0.13 12.1 4.3 1.4 1 0 0 1 1 1 0 Sec34-like family Bacillus_HBL PF05791.11 CBY38060.1 - 0.086 12.7 4.7 0.19 11.5 4.7 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FYVE PF01363.21 CBY38060.1 - 0.1 12.8 7.7 0.27 11.4 1.5 2.4 2 0 0 2 2 2 0 FYVE zinc finger DHR10 PF18595.1 CBY38060.1 - 0.13 12.3 12.7 0.27 11.3 12.7 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 CBY38060.1 - 0.14 12.8 5.2 0.35 11.5 5.2 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal IBR PF01485.21 CBY38060.1 - 0.14 12.4 12.7 0.5 10.6 7.3 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF3450 PF11932.8 CBY38060.1 - 0.16 11.2 7.1 0.29 10.4 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.11 CBY38060.1 - 0.17 11.5 4.5 0.32 10.6 4.5 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Enkurin PF13864.6 CBY38060.1 - 0.31 11.5 7.9 0.14 12.6 3.2 2.5 1 1 1 2 2 2 0 Calmodulin-binding DUF948 PF06103.11 CBY38060.1 - 0.91 9.8 3.0 1.9 8.8 2.6 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-C3HC4_4 PF15227.6 CBY38060.1 - 0.98 9.6 11.1 2.6 8.3 6.7 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1664 PF07889.12 CBY38060.1 - 1.1 9.3 7.1 4.6 7.3 6.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CBY38060.1 - 1.5 6.7 8.0 2 6.2 8.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.6 CBY38060.1 - 1.5 8.8 12.6 0.15 12.0 6.6 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HIP1_clath_bdg PF16515.5 CBY38060.1 - 1.9 9.1 12.4 0.42 11.3 3.9 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 CBY38060.1 - 2 8.9 9.6 1.2 9.7 7.0 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF4795 PF16043.5 CBY38060.1 - 2.9 7.4 13.4 59 3.2 13.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMF_DNA_bd PF12329.8 CBY38060.1 - 3.7 7.6 15.5 2.1 8.4 11.4 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.6 CBY38060.1 - 5.7 7.1 13.3 3.1 8.0 9.6 2.3 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 CBY38060.1 - 6.2 7.3 12.5 15 6.0 11.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 CBY38060.1 - 9.6 5.3 9.8 14 4.8 7.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein Gal_Lectin PF02140.18 CBY38061.1 - 2.1e-16 60.1 2.4 4.3e-16 59.1 2.4 1.6 1 0 0 1 1 1 1 Galactose binding lectin domain Gal_Lectin PF02140.18 CBY38062.1 - 1.3e-16 60.8 2.0 2.5e-16 59.9 2.0 1.5 1 0 0 1 1 1 1 Galactose binding lectin domain Pkinase PF00069.25 CBY38063.1 - 3.3e-45 154.5 0.0 5e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38063.1 - 4.7e-19 68.7 0.0 7.3e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBY38063.1 - 0.0014 19.1 0.3 0.0048 17.4 0.3 1.9 1 1 0 1 1 1 1 PH domain ubiquitin PF00240.23 CBY38064.1 - 0.004 16.9 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Astacin PF01400.24 CBY38065.1 - 8.7e-20 71.1 0.0 8.2e-18 64.7 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) DUF5622 PF18533.1 CBY38065.1 - 0.23 11.6 0.0 0.48 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) Zona_pellucida PF00100.23 CBY38066.1 - 1e-33 117.3 0.2 1.8e-33 116.4 0.2 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain zf-C4 PF00105.18 CBY38068.1 - 3.4e-12 46.6 11.2 1.2e-11 44.9 11.2 2.0 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY38068.1 - 3.9 7.9 9.2 1 9.8 0.9 2.6 2 1 0 2 2 2 0 C1 domain C1_1 PF00130.22 CBY38068.1 - 4.6 7.2 8.7 1.2 9.1 1.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RPA_interact_C PF14768.6 CBY38068.1 - 5.4 7.7 9.9 46 4.7 8.0 2.6 2 1 0 2 2 2 0 Replication protein A interacting C-terminal Neur_chan_LBD PF02931.23 CBY38071.1 - 1.5e-45 155.3 0.8 2.4e-45 154.7 0.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY38071.1 - 9.4e-29 101.1 1.3 2.4e-25 90.0 0.1 2.2 1 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 CBY38074.1 - 2.7e-14 52.7 0.1 5.9e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 CBY38075.1 - 4.5e-11 42.7 0.1 6.5e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Bromodomain MurB_C PF02873.16 CBY38075.1 - 0.085 12.9 0.1 0.17 11.9 0.1 1.5 1 1 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Not3 PF04065.15 CBY38076.1 - 0.0011 18.4 2.4 0.0011 18.4 2.4 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component DED PF01335.21 CBY38076.1 - 0.028 14.7 2.6 0.052 13.8 2.6 1.4 1 0 0 1 1 1 0 Death effector domain GIDA_assoc PF13932.6 CBY38076.1 - 2.2 8.4 8.0 0.75 9.9 3.2 1.9 1 1 1 2 2 2 0 GidA associated domain SNF5 PF04855.12 CBY38077.1 - 1.4e-53 182.1 1.0 2.1e-28 99.7 0.0 2.7 1 1 2 3 3 3 2 SNF5 / SMARCB1 / INI1 GGDEF PF00990.21 CBY38077.1 - 0.091 12.5 0.4 0.19 11.4 0.4 1.5 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain LpoB PF13036.6 CBY38077.1 - 0.12 12.3 1.3 2.6 8.0 0.2 2.7 3 0 0 3 3 3 0 Peptidoglycan-synthase activator LpoB 40S_S4_C PF16121.5 CBY38078.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus ig PF00047.25 CBY38079.1 - 1.9e-16 60.0 8.2 8e-07 29.1 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain Ig_3 PF13927.6 CBY38079.1 - 3.9e-15 56.2 13.4 0.00014 22.4 0.2 4.2 4 1 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY38079.1 - 9.2e-13 48.1 4.4 1.6e-07 31.3 0.1 3.0 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.16 CBY38079.1 - 3.2e-12 46.4 8.0 0.012 15.6 0.2 5.0 3 2 0 3 3 3 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY38079.1 - 8.3e-12 45.3 7.9 0.00044 20.5 0.1 4.2 3 1 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY38079.1 - 1e-09 38.5 3.5 4e-09 36.6 0.1 3.0 2 1 1 3 3 3 1 Immunoglobulin V-set domain Ig_6 PF18452.1 CBY38079.1 - 1.5e-05 24.4 0.1 0.001 18.6 0.0 3.0 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY38079.1 - 0.0026 17.5 4.1 0.17 11.7 0.2 3.9 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Glycophorin_A PF01102.18 CBY38079.1 - 0.023 14.9 0.0 0.082 13.1 0.0 2.0 1 0 0 1 1 1 0 Glycophorin A C1-set PF07654.15 CBY38079.1 - 0.061 13.7 4.5 0.13 12.7 0.4 3.2 3 1 0 3 3 3 0 Immunoglobulin C1-set domain Syndecan PF01034.20 CBY38079.1 - 0.45 10.5 3.2 1.9 8.5 3.2 2.0 2 0 0 2 2 2 0 Syndecan domain Inhibitor_I78 PF11720.8 CBY38081.1 - 0.055 13.5 0.1 0.06 13.4 0.1 1.1 1 0 0 1 1 1 0 Peptidase inhibitor I78 family DUF3601 PF12208.8 CBY38083.1 - 0.08 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) Sulfotransfer_2 PF03567.14 CBY38085.1 - 2.5e-24 86.6 2.1 4.4e-24 85.8 2.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family SSF PF00474.17 CBY38086.1 - 9.4e-123 410.1 16.0 1.3e-122 409.6 16.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Nitr_red_assoc PF09655.10 CBY38086.1 - 0.0052 17.4 1.6 0.0087 16.7 1.6 1.2 1 0 0 1 1 1 1 Conserved nitrate reductase-associated protein (Nitr_red_assoc) GAPT PF11770.8 CBY38086.1 - 0.72 9.7 3.4 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) SH3_1 PF00018.28 CBY38087.1 - 4.3e-08 32.6 0.7 1e-07 31.4 0.7 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY38087.1 - 3.6e-05 23.4 0.1 8.8e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CBY38087.1 - 4e-05 23.4 0.0 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain NBP1 PF08537.10 CBY38087.1 - 0.00086 18.8 0.3 0.0014 18.2 0.3 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 SH3_16 PF18348.1 CBY38087.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 CBY38087.1 - 0.057 13.7 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Imm61 PF15598.6 CBY38087.1 - 0.092 12.6 0.3 0.26 11.2 0.1 1.8 1 1 1 2 2 2 0 Immunity protein 61 Thioredoxin_7 PF13899.6 CBY38090.1 - 0.0035 17.5 0.1 0.0098 16.1 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like MAD PF05557.13 CBY38090.1 - 0.0054 15.2 6.2 0.0073 14.7 6.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3800 PF12686.7 CBY38090.1 - 3.9 8.1 5.1 69 4.1 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) AAA_8 PF12780.7 CBY38091.1 - 7.4e-103 343.4 0.0 1.6e-102 342.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBY38091.1 - 1.1e-96 323.7 0.0 6.8e-96 321.1 0.0 2.3 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBY38091.1 - 8.1e-92 306.3 0.2 5.9e-91 303.5 0.2 2.5 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY38091.1 - 2.6e-74 248.7 0.0 3e-72 241.9 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region MT PF12777.7 CBY38091.1 - 7.2e-56 189.7 13.1 1.3e-55 188.8 13.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CBY38091.1 - 1e-54 184.8 0.0 2.3e-54 183.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY38091.1 - 6.9e-44 148.8 0.0 2e-41 140.8 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CBY38091.1 - 1.1e-21 76.9 0.1 5.1e-21 74.8 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBY38091.1 - 4.4e-17 62.4 0.1 2.2e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY38091.1 - 7.5e-07 29.2 0.0 0.046 13.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY38091.1 - 5e-06 27.0 0.0 0.2 12.1 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY38091.1 - 0.0012 19.3 3.1 0.42 11.0 0.0 3.5 3 1 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CBY38091.1 - 0.0019 17.9 0.1 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 CBY38091.1 - 0.0034 17.9 0.0 2.8 8.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBY38091.1 - 0.011 15.5 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4874 PF16173.5 CBY38091.1 - 0.019 14.7 0.3 0.92 9.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) DUF815 PF05673.13 CBY38091.1 - 0.027 13.7 0.1 5 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBY38091.1 - 0.15 12.3 0.8 2.1 8.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain Pox_EPC_I2-L1 PF12575.8 CBY38091.1 - 0.16 12.2 0.6 0.48 10.7 0.6 1.8 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 fn1 PF00039.18 CBY38092.1 - 0.0038 17.4 29.0 0.033 14.4 3.3 5.4 4 3 0 4 4 4 3 Fibronectin type I domain Mtc PF03820.17 CBY38094.1 - 5.9e-94 314.6 0.0 7.1e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier BBS2_Mid PF14783.6 CBY38096.1 - 3.2e-05 23.9 0.0 0.02 14.9 0.0 2.9 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region IF4E PF01652.18 CBY38097.1 - 9.9e-50 168.4 0.3 1.3e-49 168.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TUDOR PF00567.24 CBY38098.1 - 2.3e-10 40.5 0.0 9e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Tudor domain DUF3836 PF12930.7 CBY38098.1 - 0.016 15.0 0.3 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF3836) ArfGap PF01412.18 CBY38099.1 - 1e-31 109.5 3.2 2.7e-31 108.0 3.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3967 PF13152.6 CBY38100.1 - 0.2 11.5 0.2 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) SprT-like PF10263.9 CBY38101.1 - 1.5e-20 73.1 0.0 3.3e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 SprT-like family Tox-MPTase3 PF15639.6 CBY38101.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 3 SRP72 PF08492.12 CBY38102.1 - 0.13 12.7 0.5 0.13 12.7 0.5 2.9 4 0 0 4 4 4 0 SRP72 RNA-binding domain Trypsin PF00089.26 CBY38103.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY38104.1 - 2e-24 86.6 0.1 2.4e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin DUF547 PF04784.14 CBY38106.1 - 1.1e-33 115.8 0.0 2.1e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 CBY38106.1 - 0.0042 17.1 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4520 PF15016.6 CBY38106.1 - 0.023 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF5032 PF16435.5 CBY38106.1 - 0.058 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Glutaredoxin PF00462.24 CBY38106.1 - 0.12 12.6 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin Dimerisation PF08100.11 CBY38107.1 - 0.0063 16.5 0.2 0.4 10.7 0.0 2.5 2 0 0 2 2 2 1 Dimerisation domain DUF1146 PF06612.11 CBY38107.1 - 0.086 12.9 1.2 0.41 10.7 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) Y_phosphatase PF00102.27 CBY38108.1 - 1.1e-129 430.9 0.0 2.2e-73 246.7 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CBY38108.1 - 1.9e-10 40.7 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain fn3 PF00041.21 CBY38108.1 - 3.2e-10 40.2 0.0 2.3e-08 34.2 0.0 3.3 3 0 0 3 3 3 1 Fibronectin type III domain CarboxypepD_reg PF13620.6 CBY38108.1 - 0.00064 19.9 0.5 0.073 13.3 0.1 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Y_phosphatase3 PF13350.6 CBY38108.1 - 0.0036 17.3 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY38108.1 - 0.078 13.1 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Kelch_6 PF13964.6 CBY38109.1 - 0.0048 17.1 2.4 1.2 9.5 0.0 3.4 4 0 0 4 4 4 2 Kelch motif CUB PF00431.20 CBY38112.1 - 7.6e-20 71.3 0.0 1.3e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 CUB domain EGF PF00008.27 CBY38112.1 - 4.3e-17 62.1 49.7 3.9e-07 30.3 4.0 5.6 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 CBY38112.1 - 1.5e-06 28.6 35.8 2.9e-05 24.5 5.2 5.9 5 1 0 5 5 5 3 Human growth factor-like EGF EGF_2 PF07974.13 CBY38112.1 - 2e-05 24.8 47.4 0.00043 20.6 8.1 4.7 4 0 0 4 4 4 3 EGF-like domain TPR_1 PF00515.28 CBY38113.1 - 2.9e-71 232.6 19.5 1.1e-07 31.4 0.1 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 CBY38113.1 - 1e-56 188.3 27.2 4.3e-12 45.5 0.6 10.3 4 4 7 11 11 11 9 TPR repeat TPR_2 PF07719.17 CBY38113.1 - 1.3e-50 165.4 19.4 2.9e-05 23.8 0.1 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38113.1 - 1.6e-46 152.7 12.2 8.3e-05 22.5 0.1 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 CBY38113.1 - 4.3e-46 152.0 17.5 5.1e-06 26.5 0.2 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBY38113.1 - 5.6e-37 123.1 20.5 0.0002 21.2 0.0 10.4 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 CBY38113.1 - 7.8e-36 122.2 28.8 2e-07 31.2 3.7 8.2 4 4 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 CBY38113.1 - 2.4e-34 117.7 12.9 7.1e-08 33.0 0.6 7.3 3 3 4 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 CBY38113.1 - 1.7e-32 110.4 35.1 2.9e-06 26.9 1.1 10.5 10 1 1 11 11 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 CBY38113.1 - 8.2e-29 99.9 16.3 1.7e-06 28.4 1.1 7.4 5 3 3 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBY38113.1 - 1.6e-28 96.9 10.1 0.00021 21.8 0.0 9.6 3 2 8 11 11 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 CBY38113.1 - 2.9e-15 56.2 4.5 0.0091 16.1 0.2 5.8 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 CBY38113.1 - 2.6e-12 46.1 0.1 0.29 11.9 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat NARP1 PF12569.8 CBY38113.1 - 2.6e-11 43.1 1.7 0.00027 20.0 0.0 4.0 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBY38113.1 - 7e-11 42.0 17.0 0.085 13.5 0.1 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY38113.1 - 1.1e-09 38.2 9.0 0.036 13.5 0.7 4.9 1 1 4 5 5 5 3 MalT-like TPR region ANAPC3 PF12895.7 CBY38113.1 - 8.1e-09 35.6 13.4 0.00033 20.8 1.6 5.0 3 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CBY38113.1 - 6.9e-08 32.0 5.6 0.00059 19.1 2.0 4.7 1 1 2 3 3 3 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 CBY38113.1 - 4.3e-06 26.4 11.1 0.00021 20.9 0.5 3.6 4 0 0 4 4 4 2 Est1 DNA/RNA binding domain TPR_3 PF07720.12 CBY38113.1 - 3e-05 23.9 9.1 0.12 12.4 0.0 6.2 7 1 1 8 8 6 2 Tetratricopeptide repeat FAT PF02259.23 CBY38113.1 - 3.8e-05 23.1 1.2 0.55 9.4 0.0 3.4 1 1 0 2 2 2 2 FAT domain TPR_20 PF14561.6 CBY38113.1 - 0.00022 21.5 11.9 0.25 11.7 0.7 5.4 4 3 2 6 6 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBY38113.1 - 0.0014 18.1 1.0 9.8 5.7 0.0 5.5 5 0 0 5 5 5 0 SHNi-TPR SNAP PF14938.6 CBY38113.1 - 0.002 17.6 13.0 0.26 10.6 0.4 4.8 1 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP PPR PF01535.20 CBY38113.1 - 0.0029 17.7 3.9 18 5.9 0.0 6.5 7 0 0 7 7 6 0 PPR repeat DUF627 PF04781.12 CBY38113.1 - 0.0032 17.5 0.6 13 5.8 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF627) Alkyl_sulf_dimr PF14863.6 CBY38113.1 - 0.0038 17.7 2.2 7.2 7.1 0.2 3.8 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation DUF4807 PF16065.5 CBY38113.1 - 0.006 16.2 0.0 0.29 10.8 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4807) TPR_21 PF09976.9 CBY38113.1 - 0.032 13.9 11.3 5.1 6.7 0.0 5.2 3 3 1 5 5 5 0 Tetratricopeptide repeat-like domain BTAD PF03704.17 CBY38113.1 - 0.14 12.6 8.5 0.49 10.8 1.5 3.7 2 2 1 4 4 4 0 Bacterial transcriptional activator domain Mad3_BUB1_I PF08311.12 CBY38113.1 - 0.41 10.6 8.9 48 3.9 0.1 5.1 6 1 0 6 6 5 0 Mad3/BUB1 homology region 1 MIT PF04212.18 CBY38113.1 - 0.75 9.9 20.7 40 4.4 0.1 7.5 8 1 1 9 9 8 0 MIT (microtubule interacting and transport) domain Sda PF08970.10 CBY38113.1 - 5.9 6.7 10.3 75 3.2 0.1 5.9 7 0 0 7 7 7 0 Sporulation inhibitor A DUF1771 PF08590.10 CBY38113.1 - 9.6 6.7 8.3 5.5 7.4 0.3 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF1771) I-set PF07679.16 CBY38114.1 - 1.2e-76 252.8 0.8 4.3e-17 62.0 0.0 8.5 8 1 0 8 8 8 7 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY38114.1 - 6.8e-49 164.4 0.0 2.5e-13 50.4 0.0 7.5 7 0 0 7 7 7 7 Immunoglobulin domain fn3 PF00041.21 CBY38114.1 - 1.6e-34 118.1 0.0 2.6e-11 43.7 0.0 3.9 3 0 0 3 3 3 3 Fibronectin type III domain ig PF00047.25 CBY38114.1 - 3.9e-25 87.8 1.1 5.7e-08 32.8 0.0 7.6 7 1 0 7 7 7 5 Immunoglobulin domain Ig_2 PF13895.6 CBY38114.1 - 3.2e-24 85.0 0.0 5.1e-09 36.4 0.0 6.6 7 0 0 7 7 7 4 Immunoglobulin domain V-set PF07686.17 CBY38114.1 - 2.3e-21 76.0 0.0 0.0005 20.2 0.0 8.3 7 2 1 8 8 8 3 Immunoglobulin V-set domain THB PF18362.1 CBY38114.1 - 3.8e-13 48.8 2.4 1.5e-12 46.9 0.1 2.4 2 0 0 2 2 2 1 Tri-helix bundle domain Pur_ac_phosph_N PF16656.5 CBY38114.1 - 5.9e-05 23.6 0.0 0.48 11.0 0.0 3.9 4 0 0 4 4 3 1 Purple acid Phosphatase, N-terminal domain Ig_6 PF18452.1 CBY38114.1 - 0.0013 18.2 0.0 0.35 10.5 0.0 3.6 4 0 0 4 4 4 1 Immunoglobulin domain Receptor_2B4 PF11465.8 CBY38114.1 - 0.0015 18.7 0.1 0.34 11.1 0.0 3.9 4 0 0 4 4 3 1 Natural killer cell receptor 2B4 Izumo-Ig PF16706.5 CBY38114.1 - 0.015 15.3 0.2 2.3 8.3 0.0 4.2 5 0 0 5 5 4 0 Izumo-like Immunoglobulin domain fn3_2 PF16893.5 CBY38114.1 - 0.029 14.5 0.0 8.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Fibronectin type III domain MG2 PF01835.19 CBY38114.1 - 0.06 13.8 0.0 15 6.1 0.0 4.2 4 0 0 4 4 4 0 MG2 domain Herpes_gI PF01688.17 CBY38114.1 - 0.17 11.8 0.2 42 4.0 0.0 3.7 5 0 0 5 5 5 0 Alphaherpesvirus glycoprotein I Neur_chan_LBD PF02931.23 CBY38115.1 - 9.7e-31 106.9 0.2 1.7e-30 106.1 0.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Phospholip_A2_1 PF00068.19 CBY38116.1 - 1.7e-10 41.3 4.7 3.2e-10 40.4 4.7 1.4 1 0 0 1 1 1 1 Phospholipase A2 zf-C2H2_2 PF12756.7 CBY38117.1 - 1.9e-11 44.2 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Synapsin PF02078.16 CBY38118.1 - 1.7e-19 70.0 0.0 3.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Synapsin, N-terminal domain Synapsin_C PF02750.14 CBY38118.1 - 1.1e-16 60.9 0.0 2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Synapsin, ATP binding domain SART-1 PF03343.13 CBY38119.1 - 0.023 13.3 1.2 0.022 13.4 1.2 1.1 1 0 0 1 1 1 0 SART-1 family zf-C2H2 PF00096.26 CBY38121.1 - 1.9e-19 68.9 23.0 1e-06 28.8 0.6 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY38121.1 - 6.4e-12 45.3 19.4 1.5e-07 31.5 0.2 5.3 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY38121.1 - 1.2e-08 35.1 24.5 0.012 16.3 0.4 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY38121.1 - 0.00036 20.7 8.2 0.99 9.8 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY38121.1 - 0.015 15.6 7.1 8.7 6.7 0.8 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CBY38121.1 - 0.019 14.7 10.6 1.7 8.5 1.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CBY38121.1 - 0.028 14.6 6.5 3.7 7.7 0.1 3.3 1 1 2 3 3 3 0 Aberrant zinc-finger zf-LYAR PF08790.11 CBY38121.1 - 0.055 13.4 1.0 0.4 10.6 0.1 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 CBY38121.1 - 0.66 10.0 4.8 9.5 6.3 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CBY38121.1 - 1.7 9.2 10.4 2.9 8.4 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 CBY38121.1 - 2.2 8.6 7.3 1.4 9.2 0.8 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain YliH PF10799.8 CBY38122.1 - 0.034 14.1 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Trypsin PF00089.26 CBY38126.1 - 1.4e-20 74.1 0.2 1.4e-20 74.1 0.2 1.6 2 0 0 2 2 2 1 Trypsin Fer4 PF00037.27 CBY38127.1 - 7.8e-16 57.1 16.6 2.8e-09 36.4 4.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBY38127.1 - 1.4e-13 51.2 11.1 2.1e-13 50.6 11.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CBY38127.1 - 5.1e-12 46.5 6.0 1.1e-05 26.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CBY38127.1 - 1.8e-11 44.0 31.9 2.5e-07 30.7 12.0 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY38127.1 - 1.2e-10 41.3 20.6 3.4e-07 30.3 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY38127.1 - 1.5e-09 37.9 10.6 2.3e-09 37.3 10.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBY38127.1 - 3.2e-09 37.1 3.5 0.00017 22.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBY38127.1 - 2.1e-08 33.9 18.2 0.00025 21.0 5.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CBY38127.1 - 2.6e-07 30.3 12.8 0.0016 18.4 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CBY38127.1 - 1e-06 28.8 10.5 0.00024 21.4 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CBY38127.1 - 2.2e-05 24.9 11.4 0.018 15.6 1.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CBY38127.1 - 0.0038 17.7 13.8 0.35 11.4 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 CBY38127.1 - 0.0081 16.4 7.9 0.22 11.7 0.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 CBY38127.1 - 0.0087 16.9 17.4 0.038 14.9 4.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 CBY38127.1 - 0.014 15.6 5.4 1.2 9.4 0.5 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 CBY38127.1 - 0.024 14.8 4.1 0.096 12.8 0.2 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 CBY38127.1 - 0.45 11.4 11.9 1.8 9.5 1.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ECR1_N PF14382.6 CBY38128.1 - 2.7e-13 49.5 0.0 5.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CBY38128.1 - 3.3e-08 33.7 0.2 7.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 KH domain Anoctamin PF04547.12 CBY38131.1 - 2e-73 247.8 13.7 2.4e-73 247.5 13.7 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3021 PF11457.8 CBY38131.1 - 0.016 15.5 1.5 0.016 15.5 1.5 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3021) Ctr PF04145.15 CBY38131.1 - 0.13 12.8 0.6 0.84 10.2 0.0 2.5 2 2 0 2 2 2 0 Ctr copper transporter family ECF_trnsprt PF12822.7 CBY38131.1 - 1.5 8.9 9.9 0.32 11.1 4.5 2.5 1 1 2 3 3 3 0 ECF transporter, substrate-specific component CAP_N PF01213.19 CBY38132.1 - 2.5e-80 270.3 0.7 3.6e-80 269.8 0.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CBY38132.1 - 1.1e-54 184.3 8.0 1.5e-54 183.9 8.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CBY38132.1 - 0.044 13.5 2.4 0.073 12.8 2.4 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C Totivirus_coat PF05518.11 CBY38132.1 - 3.1 5.7 6.3 4.2 5.3 6.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein PMSR PF01625.21 CBY38133.1 - 2.8e-41 141.2 0.1 3.3e-41 141.0 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.21 CBY38134.1 - 2.1e-07 31.2 0.6 2.3e-07 31.1 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sulfotransfer_1 PF00685.27 CBY38136.1 - 2.1e-06 27.4 0.2 3.5e-06 26.7 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY38136.1 - 2.8e-05 24.6 0.0 0.015 15.7 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family RBD-FIP PF09457.10 CBY38137.1 - 8.8e-08 31.9 2.6 1.6e-07 31.1 2.6 1.4 1 0 0 1 1 1 1 FIP domain C2 PF00168.30 CBY38137.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain PhoU PF01895.19 CBY38137.1 - 0.12 12.8 1.0 0.24 11.9 1.0 1.4 1 0 0 1 1 1 0 PhoU domain VWD PF00094.25 CBY38138.1 - 1.5e-12 48.1 3.6 1.9e-05 25.0 0.2 2.7 2 0 0 2 2 2 2 von Willebrand factor type D domain TIL PF01826.17 CBY38138.1 - 6.9e-11 42.2 34.1 9.6e-07 29.0 13.8 5.4 5 2 1 6 6 6 2 Trypsin Inhibitor like cysteine rich domain C8 PF08742.11 CBY38138.1 - 2.5e-07 31.0 12.9 6.2e-05 23.3 2.9 5.8 5 2 2 7 7 7 2 C8 domain hEGF PF12661.7 CBY38138.1 - 9.8 7.0 15.5 0.76 10.5 0.1 5.1 4 0 0 4 4 4 0 Human growth factor-like EGF Astacin PF01400.24 CBY38139.1 - 5.4e-45 153.4 0.1 5.4e-45 153.4 0.1 1.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Mucin PF01456.17 CBY38139.1 - 0.00016 21.7 7.4 0.00016 21.7 7.4 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3439 PF11921.8 CBY38139.1 - 0.0015 18.5 12.9 0.0029 17.6 12.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) UPF0054 PF02130.17 CBY38139.1 - 0.056 13.3 0.4 0.19 11.6 0.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 DUF4304 PF14137.6 CBY38139.1 - 0.094 12.9 0.3 0.2 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) Ldl_recept_a PF00057.18 CBY38139.1 - 1.8 8.8 5.5 4 7.7 5.5 1.5 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A DUF4158 PF13700.6 CBY38142.1 - 0.095 12.5 0.6 0.27 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) MCM_lid PF17855.1 CBY38143.1 - 3.2e-15 56.3 0.8 4.8e-15 55.8 0.1 1.6 2 0 0 2 2 2 1 MCM AAA-lid domain RPN1_RPN2_N PF17781.1 CBY38144.1 - 1.4e-108 363.0 0.0 1.4e-108 363.0 0.0 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CBY38144.1 - 3.8e-29 99.6 21.3 1.2e-08 35.0 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBY38144.1 - 4.3e-05 23.8 0.4 0.49 10.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats Zip PF02535.22 CBY38144.1 - 0.039 13.2 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 CBY38144.1 - 0.092 12.5 0.7 0.19 11.4 0.7 1.4 1 0 0 1 1 1 0 Connexin Peptidase_C37 PF05416.12 CBY38144.1 - 0.13 10.7 0.1 1.2 7.6 0.6 1.9 2 0 0 2 2 2 0 Southampton virus-type processing peptidase EIIBC-GUT_N PF03612.14 CBY38144.1 - 0.19 11.4 2.7 0.39 10.4 2.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF262 PF03235.14 CBY38144.1 - 0.78 9.9 3.8 29 4.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF262 Ferlin_C PF16165.5 CBY38144.1 - 2.2 8.2 6.8 4.8 7.1 6.8 1.5 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 CBY38144.1 - 4.3 5.5 6.3 0.25 9.6 1.0 1.5 2 0 0 2 2 2 0 CDC45-like protein Sod_Cu PF00080.20 CBY38145.1 - 1.3e-58 197.2 13.4 1.1e-30 106.6 3.4 2.0 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Ldh_1_C PF02866.18 CBY38146.1 - 0.016 15.2 0.6 2.5 8.0 0.1 2.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Nrap_D6 PF17407.2 CBY38146.1 - 0.04 14.1 0.6 0.14 12.4 0.6 2.1 1 1 0 1 1 1 0 Nrap protein domain 6 Transmemb_17 PF09799.9 CBY38147.1 - 0.002 18.7 0.4 0.0027 18.2 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein Aminotran_5 PF00266.19 CBY38148.1 - 3.9e-92 309.1 0.0 5e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBY38148.1 - 5e-10 39.2 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBY38148.1 - 3.3e-06 26.7 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CBY38148.1 - 0.002 16.7 0.0 0.0029 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 CBY38148.1 - 0.022 13.5 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_S24e PF01282.19 CBY38148.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S24e Pou PF00157.17 CBY38149.1 - 2.2e-23 82.0 0.0 5.6e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY38149.1 - 3.1e-07 30.1 0.3 7.5e-07 28.9 0.3 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CBY38149.1 - 0.0041 17.4 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LcrR PF09621.10 CBY38149.1 - 0.027 13.9 0.4 0.074 12.5 0.1 1.9 2 1 0 2 2 2 0 Type III secretion system regulator (LcrR) HTH_ABP1_N PF18107.1 CBY38149.1 - 0.048 13.4 2.5 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain Mo25 PF08569.11 CBY38150.1 - 1.5e-58 198.7 12.0 2.8e-38 132.1 6.5 2.6 2 1 0 2 2 2 2 Mo25-like YMF19 PF02326.15 CBY38150.1 - 1.6 9.6 0.0 1.6 9.6 0.0 3.0 3 1 1 4 4 4 0 Plant ATP synthase F0 Guanylate_kin PF00625.21 CBY38152.1 - 2.6e-39 134.8 0.0 1e-38 132.9 0.0 1.8 1 1 0 1 1 1 1 Guanylate kinase Acyl-CoA_dh_1 PF00441.24 CBY38153.1 - 3.1e-28 98.9 0.3 3.1e-28 98.9 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 CBY38153.1 - 1.6e-21 76.9 0.0 2.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 CBY38153.1 - 8.8e-15 54.7 0.1 1.6e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY38153.1 - 9.7e-11 42.1 0.1 2.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPR_19 PF14559.6 CBY38154.1 - 0.053 14.0 1.5 3.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec2p PF06428.11 CBY38154.1 - 0.058 13.4 1.7 1.3 9.0 2.0 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAA PF00004.29 CBY38155.1 - 6.5e-11 42.8 0.0 1.7e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBY38155.1 - 1e-05 25.6 0.1 5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_8 PF12780.7 CBY38155.1 - 0.00011 21.6 0.2 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 RuvB_N PF05496.12 CBY38155.1 - 0.00081 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBY38155.1 - 0.0012 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBY38155.1 - 0.0014 18.8 0.1 0.0067 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY38155.1 - 0.0065 17.0 3.1 0.0065 17.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CBY38155.1 - 0.0071 16.3 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 CBY38155.1 - 0.0089 15.6 0.0 0.027 14.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY38155.1 - 0.012 15.8 0.1 0.41 10.9 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY38155.1 - 0.042 14.2 0.1 3.2 8.1 0.1 2.5 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 CBY38155.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 CBY38155.1 - 0.054 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.15 CBY38155.1 - 0.059 12.7 0.1 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 CBY38155.1 - 0.27 11.6 3.9 2.9 8.2 0.2 3.3 3 1 1 4 4 4 0 AAA domain AAA_17 PF13207.6 CBY38155.1 - 9 6.7 9.0 4.9 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Sushi PF00084.20 CBY38156.1 - 4.8e-09 36.7 11.0 3e-05 24.5 1.1 3.8 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) C8 PF08742.11 CBY38157.1 - 9.3e-15 54.8 11.5 2.5e-14 53.4 11.5 1.8 1 0 0 1 1 1 1 C8 domain ALS_ss_C PF10369.9 CBY38157.1 - 0.022 15.0 0.1 0.076 13.2 0.1 1.9 2 0 0 2 2 2 0 Small subunit of acetolactate synthase COesterase PF00135.28 CBY38164.1 - 3.7e-66 224.1 0.0 5.6e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY38164.1 - 0.0014 18.5 0.0 0.0052 16.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold PDEase_I PF00233.19 CBY38165.1 - 1.3e-69 234.5 5.2 2e-69 233.9 5.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ThiJ_like PF17124.5 CBY38165.1 - 0.022 14.5 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like Macscav_rec PF03523.13 CBY38165.1 - 0.038 13.9 1.3 0.095 12.6 0.1 2.2 2 0 0 2 2 2 0 Macrophage scavenger receptor TPR_2 PF07719.17 CBY38166.1 - 2.1e-07 30.5 0.0 0.089 13.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY38166.1 - 5.5e-06 26.6 0.5 0.0002 21.6 0.5 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY38166.1 - 1e-05 25.6 0.4 0.003 17.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY38166.1 - 0.0036 17.1 0.6 0.077 12.8 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY38166.1 - 0.013 15.5 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38166.1 - 0.021 15.0 1.5 2 8.8 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat FKBP_C PF00254.28 CBY38166.1 - 0.072 13.4 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase MIT PF04212.18 CBY38166.1 - 0.084 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 CBY38166.1 - 0.15 12.7 0.1 7.1 7.4 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Casc1_N PF15927.5 CBY38167.1 - 2.9e-11 43.4 1.4 2.9e-11 43.4 1.4 2.6 4 0 0 4 4 4 1 Cancer susceptibility candidate 1 N-terminus AAA_22 PF13401.6 CBY38169.1 - 2.5e-09 37.5 0.0 4.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBY38169.1 - 1.3e-06 28.9 0.0 2.3e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CBY38169.1 - 1.3e-05 25.7 0.0 1.7e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBY38169.1 - 0.00028 20.4 0.0 0.00041 19.9 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBY38169.1 - 0.0077 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 CBY38169.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBY38169.1 - 0.023 14.7 0.1 0.034 14.1 0.1 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 CBY38169.1 - 0.026 13.8 0.0 0.037 13.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 CBY38169.1 - 0.066 12.4 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CBY38169.1 - 0.07 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CBY38169.1 - 0.08 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Viral_helicase1 PF01443.18 CBY38169.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CBY38169.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain C2 PF00168.30 CBY38170.1 - 1.8e-06 28.2 0.0 5.1e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 C2 domain Hydrolase PF00702.26 CBY38171.1 - 3e-43 148.6 0.3 5.5e-43 147.7 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY38171.1 - 2.1e-05 25.0 0.2 0.00011 22.7 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY38171.1 - 0.0018 18.0 6.1 0.011 15.5 2.1 2.8 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 CBY38173.1 - 2e-21 75.6 4.4 2e-21 75.6 4.4 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY38173.1 - 0.76 9.7 3.0 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain TFIIA PF03153.13 CBY38173.1 - 2.1 8.3 12.9 2.4 8.1 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 CBY38174.1 - 6.2e-57 193.0 0.1 1.5e-56 191.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 CBY38174.1 - 9.5e-37 125.0 0.3 4e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 CBY38174.1 - 8.9e-28 97.3 0.0 2e-27 96.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY38174.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY38174.1 - 0.00051 18.9 0.0 0.00076 18.4 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pfk_N PF18468.1 CBY38174.1 - 0.035 14.5 0.0 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast RXLR_WY PF18634.1 CBY38174.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Rhodanese PF00581.20 CBY38176.1 - 1e-07 32.5 0.1 2.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Peptidase_M23_N PF18421.1 CBY38176.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain fn3 PF00041.21 CBY38177.1 - 3.8e-19 68.8 0.0 5e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain I-set PF07679.16 CBY38177.1 - 8e-09 35.4 0.0 2.7e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY38177.1 - 3.5e-05 24.3 0.1 0.00018 22.0 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CBY38177.1 - 0.00021 21.5 0.1 0.0006 20.1 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY38177.1 - 0.00094 19.7 0.5 0.015 15.9 0.0 2.9 2 2 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Invasin_D3 PF09134.10 CBY38177.1 - 0.055 13.8 0.2 0.17 12.2 0.1 1.9 1 1 0 1 1 1 0 Invasin, domain 3 Ig_5 PF16681.5 CBY38177.1 - 0.075 13.4 1.3 2.4 8.7 0.1 3.0 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain ig PF00047.25 CBY38177.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Glyco_tran_10_N PF17039.5 CBY38178.1 - 6.2e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal RXLR PF16810.5 CBY38178.1 - 0.22 11.9 3.5 0.13 12.7 1.6 1.8 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Astacin PF01400.24 CBY38179.1 - 2.9e-14 53.1 0.0 3.2e-12 46.5 0.0 2.4 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) TPR_1 PF00515.28 CBY38180.1 - 1e-23 82.1 16.8 8.3e-07 28.6 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CBY38180.1 - 4.2e-15 54.6 24.4 0.0095 16.0 0.0 9.8 10 1 0 10 10 10 4 Tetratricopeptide repeat JmjC PF02373.22 CBY38180.1 - 4.2e-13 49.7 0.3 1.2e-12 48.2 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase TPR_12 PF13424.6 CBY38180.1 - 2.8e-10 40.3 9.2 0.00016 21.9 0.0 6.2 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY38180.1 - 3e-10 39.6 0.1 0.0037 16.9 0.0 4.2 1 1 2 3 3 3 3 TPR repeat TPR_19 PF14559.6 CBY38180.1 - 6.9e-10 39.3 0.2 0.0039 17.7 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY38180.1 - 7.6e-10 39.3 0.0 0.0042 17.7 0.0 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38180.1 - 6.9e-09 35.2 16.8 0.13 12.6 0.0 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY38180.1 - 2.5e-08 33.7 0.1 0.076 13.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY38180.1 - 4.1e-06 27.2 2.4 0.59 11.1 0.1 5.0 4 2 2 6 6 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBY38180.1 - 4.8e-05 23.4 0.1 0.00082 19.5 0.0 2.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY38180.1 - 0.045 13.6 0.1 53 3.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY38180.1 - 0.068 12.2 0.1 4.6 6.1 0.0 2.3 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY38180.1 - 0.72 10.6 14.4 1.1e+02 3.7 0.0 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat Branch PF02485.21 CBY38181.1 - 4.3e-50 170.5 0.0 5.5e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF5516 PF17637.2 CBY38181.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5516) Zona_pellucida PF00100.23 CBY38182.1 - 1.6e-18 67.4 0.9 1.9e-18 67.2 0.9 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF PF00008.27 CBY38183.1 - 0.0026 18.0 1.4 0.005 17.1 1.4 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 CBY38183.1 - 0.0048 17.5 4.1 0.01 16.4 4.1 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_3 PF12947.7 CBY38183.1 - 0.013 15.7 1.4 0.023 14.9 1.4 1.4 1 0 0 1 1 1 0 EGF domain EGF_2 PF07974.13 CBY38183.1 - 0.016 15.6 3.2 0.027 14.8 3.2 1.4 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 CBY38183.1 - 0.023 14.8 2.4 0.023 14.8 2.4 1.4 1 1 0 1 1 1 0 Laminin EGF domain Plasmod_Pvs28 PF06247.11 CBY38183.1 - 0.087 13.1 1.2 0.14 12.5 1.2 1.3 1 0 0 1 1 1 0 Pvs28 EGF domain Ax_dynein_light PF10211.9 CBY38184.1 - 2.3e-74 249.4 9.5 2.7e-74 249.2 9.5 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 CBY38184.1 - 0.016 15.8 8.2 0.016 15.8 8.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 CBY38184.1 - 0.019 15.1 5.5 0.019 15.1 5.5 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBY38184.1 - 0.092 12.8 3.0 0.16 12.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Stathmin PF00836.19 CBY38184.1 - 0.33 10.9 13.7 0.13 12.2 11.0 1.7 2 0 0 2 2 2 0 Stathmin family TMEM192 PF14802.6 CBY38184.1 - 0.41 9.7 4.2 0.56 9.3 4.2 1.2 1 0 0 1 1 1 0 TMEM192 family FlaC_arch PF05377.11 CBY38184.1 - 0.56 10.6 3.6 13 6.3 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 CBY38184.1 - 0.66 10.2 12.6 0.14 12.4 9.3 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TSNAXIP1_N PF15739.5 CBY38184.1 - 0.74 10.2 15.7 0.63 10.4 3.1 2.8 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus Spc24 PF08286.11 CBY38184.1 - 2.7 8.3 8.3 11 6.3 8.4 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ZapB PF06005.12 CBY38184.1 - 2.9 8.4 15.7 28 5.2 15.7 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 CBY38184.1 - 5.2 7.7 8.6 0.46 11.1 3.8 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF5320 PF17253.2 CBY38184.1 - 5.8 8.1 7.3 51 5.0 3.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) GTP_EFTU PF00009.27 CBY38185.1 - 2.6e-21 76.1 0.0 4.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CBY38185.1 - 1.7e-06 28.2 0.1 0.00043 20.5 0.1 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBY38185.1 - 7.3e-05 22.7 0.2 0.096 12.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU_D2 PF03144.25 CBY38185.1 - 0.0003 21.1 0.0 0.0041 17.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Ras PF00071.22 CBY38185.1 - 0.00049 19.7 0.1 0.014 15.0 0.1 2.4 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.18 CBY38185.1 - 0.0033 17.0 0.2 0.69 9.4 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CBY38185.1 - 0.0052 16.9 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBY38185.1 - 0.0053 16.6 0.0 0.077 12.8 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CBY38185.1 - 0.0087 15.8 0.1 9.1 6.0 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CBY38185.1 - 0.069 12.6 0.2 4.3 6.8 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family Hanta_nucleocap PF00846.18 CBY38185.1 - 0.086 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Nop14 PF04147.12 CBY38186.1 - 9.6e-30 103.5 51.3 2.9e-16 58.9 11.0 2.8 1 1 1 2 2 2 2 Nop14-like family Aida_N PF08910.10 CBY38186.1 - 0.028 14.8 1.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 Aida N-terminus Phage_TAC_1 PF06222.11 CBY38186.1 - 0.11 12.3 1.3 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Phage tail assembly chaperone RXT2_N PF08595.11 CBY38186.1 - 0.27 11.2 24.7 0.87 9.6 13.4 2.9 3 1 0 3 3 3 0 RXT2-like, N-terminal Nop14 PF04147.12 CBY38187.1 - 7.7e-42 143.5 29.7 8.5e-42 143.4 29.7 1.0 1 0 0 1 1 1 1 Nop14-like family DUF45 PF01863.17 CBY38187.1 - 1.5 8.8 8.4 0.24 11.4 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 TIC20 PF16166.5 CBY38189.1 - 0.0099 15.7 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like CrgA PF06781.12 CBY38189.1 - 0.18 11.9 2.1 0.29 11.2 0.1 2.3 2 1 1 3 3 3 0 Cell division protein CrgA Kinin PF08260.11 CBY38190.1 - 0.47 11.1 3.2 16 6.4 0.3 3.3 2 0 0 2 2 2 0 Insect kinin peptide Rad51 PF08423.11 CBY38192.1 - 1.2e-112 375.3 0.1 1.8e-112 374.8 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY38192.1 - 3.3e-10 39.9 0.2 5e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBY38192.1 - 5.1e-07 29.5 0.0 7.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY38192.1 - 6.7e-05 22.4 0.8 0.00029 20.3 0.8 2.0 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY38192.1 - 0.012 16.2 0.1 0.023 15.3 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3173 PF11372.8 CBY38192.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3173) GvpD PF07088.11 CBY38192.1 - 0.12 10.9 0.0 0.27 9.8 0.0 1.5 1 0 0 1 1 1 0 GvpD gas vesicle protein Pro_isomerase PF00160.21 CBY38194.1 - 2.8e-16 60.2 1.2 2.8e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 CBY38197.1 - 6.6e-53 178.6 0.1 7.3e-53 178.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY38197.1 - 1.3e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY38197.1 - 4.1e-09 36.1 0.1 4.5e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY38197.1 - 8.2e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY38197.1 - 9.5e-05 22.0 0.1 0.00028 20.5 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY38197.1 - 0.001 19.0 0.6 0.74 9.7 0.3 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CBY38197.1 - 0.0012 18.1 0.1 0.13 11.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ank_2 PF12796.7 CBY38198.1 - 2.5e-17 63.2 0.5 5.8e-09 36.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY38198.1 - 1.9e-14 52.3 2.0 0.0039 17.6 0.0 5.4 4 0 0 4 4 4 4 Ankyrin repeat Ion_trans PF00520.31 CBY38198.1 - 2.3e-14 53.2 18.6 7.5e-14 51.5 18.5 1.8 1 1 1 2 2 2 1 Ion transport protein Ank_5 PF13857.6 CBY38198.1 - 2.9e-14 53.0 4.3 3.8e-06 27.1 0.2 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY38198.1 - 7.7e-14 51.9 1.5 0.0042 17.6 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY38198.1 - 8.9e-13 48.1 6.2 0.009 16.4 0.2 5.6 5 0 0 5 5 5 4 Ankyrin repeat PKD_channel PF08016.12 CBY38198.1 - 2.4e-08 33.1 13.9 2.4e-08 33.1 13.9 1.8 2 1 0 2 2 2 1 Polycystin cation channel DUF1368 PF07112.11 CBY38199.1 - 0.015 14.2 1.6 0.024 13.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Gemini_V2 PF01524.17 CBY38199.1 - 0.047 13.9 0.1 0.51 10.6 0.0 2.4 1 1 1 2 2 2 0 Geminivirus V2 protein DUF2452 PF10504.9 CBY38200.1 - 2.6e-24 85.5 1.4 2.9e-24 85.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) CBF_beta PF02312.17 CBY38200.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit Ig_3 PF13927.6 CBY38202.1 - 6.3e-30 103.6 3.6 1.1e-09 38.7 0.1 4.5 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY38202.1 - 9.8e-28 96.3 4.3 1.5e-10 41.3 0.1 4.4 4 0 0 4 4 4 3 Immunoglobulin domain I-set PF07679.16 CBY38202.1 - 2.9e-26 91.3 0.4 8.4e-08 32.2 0.0 4.6 4 1 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 CBY38202.1 - 4.6e-19 68.4 4.0 2.6e-07 30.7 0.0 4.6 3 2 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY38202.1 - 1.1e-12 48.0 11.6 0.034 14.3 0.0 6.9 4 3 3 7 7 7 5 Immunoglobulin V-set domain Ig_4 PF16680.5 CBY38202.1 - 1.8e-11 44.1 2.0 0.0069 16.6 0.0 4.3 4 0 0 4 4 4 3 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CBY38202.1 - 6.6e-08 32.5 0.0 0.27 11.3 0.0 4.3 4 0 0 4 4 4 2 Izumo-like Immunoglobulin domain Ig_6 PF18452.1 CBY38202.1 - 0.00034 20.1 0.0 1.6 8.4 0.0 3.7 4 0 0 4 4 4 2 Immunoglobulin domain FlgD_ig PF13860.6 CBY38202.1 - 0.033 14.0 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain fn3 PF00041.21 CBY38202.1 - 0.046 14.1 0.2 6.1 7.3 0.0 3.6 4 0 0 4 4 4 0 Fibronectin type III domain V-set_CD47 PF08204.11 CBY38202.1 - 0.053 13.5 1.0 1.4 8.9 0.0 3.3 3 1 1 4 4 4 0 CD47 immunoglobulin-like domain C2-set PF05790.15 CBY38202.1 - 0.097 12.9 0.1 2 8.7 0.1 3.1 4 0 0 4 4 4 0 Immunoglobulin C2-set domain Golgin_A5 PF09787.9 CBY38203.1 - 0.0011 18.5 12.6 0.0011 18.5 12.6 2.4 1 1 1 2 2 2 2 Golgin subfamily A member 5 Cep57_CLD PF14073.6 CBY38203.1 - 0.019 15.0 8.7 0.019 15.0 8.7 3.3 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 HPIP PF15226.6 CBY38203.1 - 0.14 12.5 0.2 0.4 11.1 0.2 1.8 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family IFT57 PF10498.9 CBY38203.1 - 3.2 6.6 34.2 0.76 8.7 23.5 2.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TFIIB PF00382.19 CBY38206.1 - 6.2e-27 93.4 0.0 1.4e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CBY38206.1 - 6.8e-11 41.5 2.4 6.8e-11 41.5 2.4 2.2 3 0 0 3 3 3 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 CBY38206.1 - 0.012 15.5 0.8 0.029 14.3 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RB_B PF01857.20 CBY38206.1 - 0.05 13.6 0.2 0.098 12.7 0.2 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 CBY38206.1 - 1.3 8.5 4.1 5.3 6.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 CBY38206.1 - 4.8 7.2 6.6 0.75 9.8 2.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Nic96 PF04097.14 CBY38207.1 - 1e-168 562.7 0.0 1.2e-168 562.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RAMP4 PF06624.12 CBY38207.1 - 9.5e-24 83.2 0.1 2.1e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Clathrin PF00637.20 CBY38207.1 - 0.031 14.2 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS Peptidase_M16_M PF16187.5 CBY38207.1 - 0.04 13.2 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 ANAPC3 PF12895.7 CBY38207.1 - 0.069 13.4 1.1 0.42 10.9 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Radical_SAM PF04055.21 CBY38208.1 - 3.8e-21 76.2 2.2 4.2e-21 76.0 0.3 2.2 2 0 0 2 2 2 1 Radical SAM superfamily UPF0242 PF06785.11 CBY38208.1 - 0.0026 17.9 6.0 0.0026 17.9 6.0 10.2 1 1 7 8 8 8 1 Uncharacterised protein family (UPF0242) N-terminus TRAM PF01938.20 CBY38208.1 - 0.0086 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Fib_alpha PF08702.10 CBY38208.1 - 0.0091 16.2 7.9 0.0091 16.2 7.9 11.0 3 2 8 11 11 11 3 Fibrinogen alpha/beta chain family UPF0061 PF02696.14 CBY38209.1 - 1.1e-39 136.5 0.0 1.8e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Phospholip_A2_1 PF00068.19 CBY38209.1 - 9.9e-16 58.2 10.0 1.7e-15 57.5 10.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 Toxin_2 PF00451.19 CBY38209.1 - 0.17 12.2 2.4 0.36 11.2 2.4 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 Myosin_head PF00063.21 CBY38210.1 - 1e-269 896.5 0.8 2.3e-269 895.3 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY38210.1 - 2.4e-39 135.0 86.0 3.4e-39 134.5 86.0 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY38210.1 - 1.3e-07 31.3 3.3 3.5e-07 29.9 3.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 CBY38210.1 - 0.0024 17.5 1.3 0.35 10.8 0.2 2.5 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY38210.1 - 0.017 15.4 0.5 0.067 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY38210.1 - 0.36 11.2 0.0 0.36 11.2 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain DUF4407 PF14362.6 CBY38210.1 - 1.5 8.1 52.7 2.5 7.4 8.8 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 CBY38212.1 - 1.4e-08 34.5 0.0 4.2e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY38212.1 - 0.023 14.8 0.3 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif GrpE PF01025.19 CBY38213.1 - 7.6e-35 120.0 10.8 1.6e-34 119.0 10.8 1.5 1 1 0 1 1 1 1 GrpE AAA_13 PF13166.6 CBY38213.1 - 0.15 10.7 8.7 0.18 10.4 8.7 1.1 1 0 0 1 1 1 0 AAA domain T2SSM PF04612.12 CBY38213.1 - 0.3 11.1 2.7 0.49 10.5 2.7 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Cauli_AT PF03233.13 CBY38213.1 - 0.67 9.9 5.3 1.3 8.9 5.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein TMPIT PF07851.13 CBY38213.1 - 7.5 5.7 6.1 9.8 5.3 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein MMADHC PF10229.9 CBY38214.1 - 2.1e-24 86.7 0.2 2.6e-24 86.4 0.2 1.3 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Spc7 PF08317.11 CBY38216.1 - 0.77 8.6 67.2 1.3 7.8 22.5 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein MtrB PF05440.12 CBY38216.1 - 1.5 9.3 3.4 2.5 8.6 0.1 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B YgbB PF02542.16 CBY38216.1 - 2 8.7 7.6 0.59 10.4 0.4 3.1 1 1 2 3 3 3 0 YgbB family MbeD_MobD PF04899.12 CBY38216.1 - 3.8 7.7 28.4 2.3 8.4 2.8 6.2 5 2 2 7 7 7 0 MbeD/MobD like V_ATPase_I PF01496.19 CBY38217.1 - 0.0062 14.5 9.3 0.0069 14.4 9.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CUTL PF16557.5 CBY38217.1 - 0.049 13.8 0.3 0.098 12.9 0.2 1.6 1 1 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Laminin_I PF06008.14 CBY38217.1 - 0.084 12.6 15.1 0.083 12.6 12.7 1.8 1 1 1 2 2 2 0 Laminin Domain I PIN_8 PF18476.1 CBY38217.1 - 0.17 11.7 7.6 0.23 11.3 7.6 1.3 1 0 0 1 1 1 0 PIN like domain UPF0449 PF15136.6 CBY38217.1 - 0.6 10.6 5.5 0.32 11.5 3.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 UPF0242 PF06785.11 CBY38217.1 - 1.9 8.6 14.3 0.14 12.2 7.5 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 CBY38217.1 - 5.2 7.5 13.9 11 6.5 10.5 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Carboxyl_trans PF01039.22 CBY38218.1 - 2.5e-141 471.7 0.3 3.1e-141 471.4 0.3 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBY38218.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) DUF2214 PF09980.9 CBY38219.1 - 0.018 14.8 0.5 0.02 14.7 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) PHD PF00628.29 CBY38221.1 - 5.8e-05 22.9 9.2 5.8e-05 22.9 9.2 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CBY38221.1 - 0.0096 15.5 1.9 0.019 14.5 1.9 1.5 1 0 0 1 1 1 1 PHD-finger Elf1 PF05129.13 CBY38221.1 - 0.38 10.8 7.1 0.35 10.9 0.6 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DDT PF02791.17 CBY38222.1 - 9.9e-08 32.2 3.5 4.7e-07 30.0 1.8 2.4 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 CBY38222.1 - 5e-07 30.1 3.2 5e-07 30.1 3.2 4.7 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CBY38222.1 - 0.0001 22.1 8.5 0.00025 20.9 8.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY38222.1 - 0.2 11.3 2.5 0.42 10.2 2.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 CBY38222.1 - 0.22 11.7 5.3 0.68 10.1 5.3 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 CBY38222.1 - 1.6 8.7 4.9 4.8 7.2 4.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CUE PF02845.16 CBY38223.1 - 1.1e-05 24.9 0.1 2.5e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain Importin_rep_6 PF18829.1 CBY38223.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.2 3 1 0 3 3 3 0 Importin repeat 6 DUF960 PF06124.11 CBY38223.1 - 0.88 10.3 4.6 0.25 12.0 0.7 2.1 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) SIR2 PF02146.17 CBY38225.1 - 1.4e-14 54.4 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.12 CBY38225.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SIR2 PF02146.17 CBY38226.1 - 0.00021 21.3 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.11 CBY38226.1 - 0.021 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 EzrA PF06160.12 CBY38226.1 - 0.062 11.5 0.1 0.075 11.2 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TFA2_Winged_2 PF18121.1 CBY38226.1 - 0.072 12.8 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 YvrJ PF12841.7 CBY38226.1 - 0.17 11.4 0.7 0.26 10.9 0.7 1.3 1 0 0 1 1 1 0 YvrJ protein family Ank_5 PF13857.6 CBY38227.1 - 0.00021 21.5 0.1 0.00034 20.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY38227.1 - 0.0073 16.9 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) OATP PF03137.20 CBY38228.1 - 5.4e-28 97.6 0.2 7.2e-28 97.2 0.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Luteo_PO PF04662.13 CBY38228.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 0 Luteovirus P0 protein OATP PF03137.20 CBY38229.1 - 9.9e-49 166.0 6.5 1.4e-48 165.5 6.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.6 CBY38229.1 - 7.7 6.6 8.2 5.6 7.1 1.8 2.5 2 0 0 2 2 2 0 Glycine zipper TFIIA PF03153.13 CBY38232.1 - 7.1e-40 138.3 5.5 2.6e-21 77.1 6.7 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Iso_dh PF00180.20 CBY38234.1 - 3.5e-57 194.1 0.0 4.7e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 CBY38234.1 - 0.0083 16.8 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Phenylalanine zipper Pkinase PF00069.25 CBY38235.1 - 2.8e-65 220.3 0.3 6.8e-65 219.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38235.1 - 9.2e-29 100.5 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY38235.1 - 2.6e-07 30.3 0.0 4.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY38235.1 - 5.7e-05 22.6 0.8 7.7e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPOUT_MTase_2 PF14419.6 CBY38235.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP APH PF01636.23 CBY38235.1 - 0.2 11.6 0.0 16 5.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family O-FucT PF10250.9 CBY38236.1 - 1.4e-07 31.6 0.5 1.7e-06 28.0 0.5 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_binding_3 PF13727.6 CBY38236.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain YhhN PF07947.14 CBY38237.1 - 6e-33 114.0 9.9 7.7e-33 113.6 9.9 1.1 1 0 0 1 1 1 1 YhhN family HMG_box PF00505.19 CBY38238.1 - 1.5e-17 63.7 0.2 3.6e-17 62.5 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY38238.1 - 1.3e-11 45.0 0.2 1.3e-11 45.0 0.2 1.7 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 CBY38238.1 - 0.072 13.7 4.2 0.057 14.0 2.5 1.9 1 1 0 1 1 1 0 YABBY protein HMG_box_5 PF14887.6 CBY38238.1 - 0.073 13.0 0.2 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Phage_P2_GpU PF06995.11 CBY38239.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phage P2 GpU Neprosin_AP PF14365.6 CBY38239.1 - 0.41 11.1 5.4 1.2 9.7 0.6 2.4 2 0 0 2 2 2 0 Neprosin activation peptide Glycos_transf_1 PF00534.20 CBY38240.1 - 4.9e-06 26.2 0.0 5.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY38241.1 - 3.2e-11 43.5 0.0 8.7e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CBY38241.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBY38241.1 - 0.0029 18.0 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3021 PF11457.8 CBY38241.1 - 0.12 12.7 0.1 0.19 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) RNase_Zc3h12a PF11977.8 CBY38242.1 - 1.8e-28 99.3 0.0 3.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Peripla_BP_3 PF13377.6 CBY38242.1 - 0.0014 19.0 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 2 Periplasmic binding protein-like domain XPG_I PF00867.18 CBY38243.1 - 1.6e-13 50.8 1.1 6.6e-13 48.8 0.0 2.7 3 1 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CBY38243.1 - 2.9e-05 24.6 0.2 0.00081 20.0 0.0 2.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF1344 PF07076.11 CBY38243.1 - 0.036 14.0 0.1 0.09 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF424 PF04242.13 CBY38243.1 - 0.13 12.6 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF424) Cadherin_C PF01049.17 CBY38244.1 - 4.8e-12 46.4 0.3 6.5e-12 46.0 0.3 1.2 1 0 0 1 1 1 1 Cadherin cytoplasmic region Adeno_E3_CR2 PF02439.15 CBY38245.1 - 0.027 14.2 0.4 0.054 13.3 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF898 PF05987.13 CBY38245.1 - 0.095 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) LapA_dom PF06305.11 CBY38245.1 - 0.29 11.0 3.0 0.56 10.1 3.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Cadherin PF00028.17 CBY38246.1 - 1.3e-10 41.6 0.6 2.9e-08 34.0 0.6 3.5 3 0 0 3 3 3 1 Cadherin domain Ribosomal_L27e PF01777.18 CBY38246.1 - 0.086 13.2 0.8 20 5.6 1.0 2.8 2 0 0 2 2 2 0 Ribosomal L27e protein family FctA PF12892.7 CBY38246.1 - 0.51 11.2 2.8 13 6.7 0.1 2.8 3 0 0 3 3 3 0 Spy0128-like isopeptide containing domain Ion_trans PF00520.31 CBY38247.1 - 4.1e-09 36.0 16.4 5.4e-09 35.6 11.4 2.1 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CBY38247.1 - 2.5 6.7 20.9 0.97 8.0 15.8 2.4 2 1 0 2 2 2 0 Polycystin cation channel RPAP2_Rtr1 PF04181.13 CBY38248.1 - 7.7e-19 67.8 1.7 1.4e-18 67.0 1.7 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family KRTDAP PF15200.6 CBY38248.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Keratinocyte differentiation-associated COQ7 PF03232.13 CBY38249.1 - 5.6e-70 234.6 0.6 6.4e-70 234.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CBY38249.1 - 0.0024 18.2 0.2 0.007 16.8 0.2 1.8 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 CBY38249.1 - 0.016 15.4 0.2 0.073 13.3 0.0 2.0 1 1 1 2 2 2 0 Ferritin-like domain DUF3730 PF12530.8 CBY38249.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Ssu72 PF04722.13 CBY38253.1 - 7.1e-78 260.6 1.3 8e-78 260.4 1.3 1.0 1 0 0 1 1 1 1 Ssu72-like protein RRM_1 PF00076.22 CBY38254.1 - 3e-17 62.2 0.0 4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY38254.1 - 5.9e-06 25.9 0.0 7.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CBY38254.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain CCDC71L PF15374.6 CBY38254.1 - 0.084 12.1 5.5 0.096 11.9 5.5 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PRE_C2HC PF07530.11 CBY38254.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers RNA_bind PF08675.11 CBY38254.1 - 0.2 11.7 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain I-set PF07679.16 CBY38255.1 - 1.6e-38 130.6 0.0 4.8e-18 65.0 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY38255.1 - 9.4e-27 93.4 4.8 2.1e-13 50.7 0.0 3.8 4 1 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 CBY38255.1 - 3.5e-16 59.1 0.1 4.5e-08 33.2 0.1 3.0 3 0 0 3 3 3 2 Immunoglobulin domain Ig_2 PF13895.6 CBY38255.1 - 1.9e-15 57.0 0.0 4e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Immunoglobulin domain C2-set_2 PF08205.12 CBY38255.1 - 4e-07 30.0 0.9 0.045 13.8 0.3 3.4 2 1 1 3 3 3 2 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY38255.1 - 2.3e-06 27.7 0.2 0.025 14.7 0.0 3.7 3 2 1 4 4 4 2 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY38255.1 - 0.00021 21.3 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Izumo-like Immunoglobulin domain MBG_2 PF18676.1 CBY38255.1 - 0.0076 16.9 0.1 0.52 11.0 0.0 2.9 3 0 0 3 3 3 1 MBG domain (YGX type) DUF4198 PF10670.9 CBY38255.1 - 0.019 15.3 0.2 1.8 8.8 0.0 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4198) C1-set PF07654.15 CBY38255.1 - 0.02 15.3 0.5 5.1 7.6 0.2 3.1 2 1 0 2 2 2 0 Immunoglobulin C1-set domain DUF5599 PF18141.1 CBY38255.1 - 0.087 13.1 0.0 5.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5599) Ig_5 PF16681.5 CBY38255.1 - 0.14 12.6 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain CUB PF00431.20 CBY38257.1 - 0.0003 21.1 0.1 0.00042 20.6 0.1 1.3 1 0 0 1 1 1 1 CUB domain LAX PF15681.5 CBY38257.1 - 0.053 12.3 0.1 0.094 11.5 0.1 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X Phytochelatin_C PF09328.10 CBY38258.1 - 0.017 14.4 0.4 0.027 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) HMG_box PF00505.19 CBY38259.1 - 4.4e-13 49.4 0.5 8e-13 48.6 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY38259.1 - 3.1e-06 27.7 0.4 5.3e-06 26.9 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain Tetraspanin PF00335.20 CBY38260.1 - 0.00011 22.0 9.2 0.00011 22.0 9.2 1.9 2 0 0 2 2 2 1 Tetraspanin family fn3 PF00041.21 CBY38261.1 - 0.053 13.9 0.0 0.087 13.2 0.0 1.5 1 1 0 1 1 1 0 Fibronectin type III domain zf-UBR PF02207.20 CBY38262.1 - 4.8e-06 26.7 18.2 1.1e-05 25.4 18.2 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Nop14 PF04147.12 CBY38262.1 - 4.8 5.3 19.2 13 3.9 19.2 1.6 1 0 0 1 1 1 0 Nop14-like family EF-hand_7 PF13499.6 CBY38263.1 - 2e-23 82.6 4.6 2.4e-16 59.9 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY38263.1 - 2.3e-22 76.8 6.8 2.6e-07 29.7 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY38263.1 - 1e-19 68.7 4.5 1.9e-05 24.2 0.2 3.8 4 0 0 4 4 3 3 EF-hand domain EF-hand_5 PF13202.6 CBY38263.1 - 1.4e-14 52.8 7.7 0.00046 19.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CBY38263.1 - 8.3e-14 51.2 7.3 0.00037 20.3 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CBY38263.1 - 3.7e-07 30.0 2.1 0.023 14.7 0.0 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY38263.1 - 0.0021 18.4 0.6 0.49 10.7 0.1 3.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1801 PF08818.11 CBY38263.1 - 0.039 14.5 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DU1801) Caleosin PF05042.13 CBY38263.1 - 0.055 13.4 1.5 6.8 6.6 0.0 3.2 2 1 2 4 4 4 0 Caleosin related protein EF-hand_9 PF14658.6 CBY38263.1 - 0.06 13.7 0.0 3.1 8.2 0.0 2.6 1 1 2 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 CBY38263.1 - 0.12 12.5 1.2 1.5 9.1 0.6 2.6 2 1 0 2 2 2 0 Dockerin type I domain Pyrid_oxidase_2 PF13883.6 CBY38264.1 - 9.4e-22 77.8 0.0 1e-21 77.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Gln-synt_N PF03951.19 CBY38265.1 - 4.8e-14 51.8 0.0 7.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 CBY38265.1 - 0.0034 16.4 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain bZIP_1 PF00170.21 CBY38268.1 - 1.7e-08 34.5 22.2 3.6e-08 33.4 22.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY38268.1 - 8.9e-05 22.5 14.3 8.9e-05 22.5 14.3 2.4 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY38268.1 - 0.00021 21.8 14.6 0.00021 21.8 14.6 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor adh_short PF00106.25 CBY38269.1 - 1e-27 96.9 0.0 1.2e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY38269.1 - 1.9e-13 50.5 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY38269.1 - 0.00034 20.6 0.0 0.00045 20.2 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY38269.1 - 0.0022 17.9 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CBY38269.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 CBY38269.1 - 0.13 11.6 2.2 6 6.2 0.0 2.2 2 0 0 2 2 2 0 ThiF family AAA_30 PF13604.6 CBY38271.1 - 0.029 14.1 0.1 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain MIP PF00230.20 CBY38273.1 - 2.4e-33 115.7 12.3 3.7e-33 115.2 12.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein Cas9_b_hairpin PF17893.1 CBY38274.1 - 0.046 13.5 0.0 3.1 7.7 0.0 2.4 1 1 1 2 2 2 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain Pkinase PF00069.25 CBY38276.1 - 9.5e-42 143.2 0.1 1.4e-41 142.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38276.1 - 1.9e-20 73.3 0.1 2.5e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_48 PF17906.1 CBY38276.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Phospholip_A2_1 PF00068.19 CBY38277.1 - 7e-05 23.3 5.1 7e-05 23.3 5.1 2.1 2 0 0 2 2 2 1 Phospholipase A2 fn3 PF00041.21 CBY38278.1 - 4e-18 65.5 4.5 5.2e-08 33.1 0.0 5.0 3 1 1 4 4 4 4 Fibronectin type III domain CENP-T_N PF16171.5 CBY38279.1 - 0.05 12.5 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus SNF2_N PF00176.23 CBY38281.1 - 5.9e-62 209.4 0.9 9.4e-62 208.7 0.9 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY38281.1 - 2.6e-19 69.6 0.0 2e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 CBY38281.1 - 1.2e-14 53.9 17.0 5.2e-12 45.5 0.3 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CBY38281.1 - 3.1e-11 43.6 0.0 1.2e-10 41.7 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 CBY38281.1 - 5.6e-07 29.9 4.6 0.049 13.8 0.0 4.4 5 0 0 5 5 5 2 CHDCT2 (NUC038) domain DEAD PF00270.29 CBY38281.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBY38281.1 - 0.0019 17.9 0.1 0.0081 15.8 0.1 2.1 1 1 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-bind_7 PF15963.5 CBY38281.1 - 0.0023 17.8 2.3 0.0094 15.8 0.0 3.0 2 0 0 2 2 2 1 Myb DNA-binding like AAA_22 PF13401.6 CBY38281.1 - 0.076 13.3 0.1 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 CBY38281.1 - 0.13 12.5 10.2 10 6.4 0.1 3.9 4 0 0 4 4 4 0 Myb-like DNA-binding domain zf-C2H2_jaz PF12171.8 CBY38282.1 - 1.5e-06 28.3 0.6 4.4e-06 26.8 0.6 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY38282.1 - 0.00069 19.9 0.3 0.0016 18.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY38282.1 - 0.0016 18.2 3.8 0.0052 16.5 3.8 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY38282.1 - 0.0076 16.6 1.6 0.015 15.6 1.6 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) MRNIP PF15749.5 CBY38282.1 - 1.4 9.6 19.5 0.023 15.4 6.4 3.0 2 1 1 3 3 3 0 MRN-interacting protein bZIP_1 PF00170.21 CBY38283.1 - 8.7e-10 38.6 11.4 3.2e-09 36.7 11.4 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY38283.1 - 3.5e-07 30.2 11.5 3.5e-07 30.2 11.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY38283.1 - 0.014 15.9 3.2 0.014 15.9 3.2 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor TarH PF02203.15 CBY38283.1 - 0.021 14.7 1.6 0.044 13.7 1.6 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue Ni_hydr_CYTB PF01292.20 CBY38284.1 - 0.021 14.4 0.1 0.025 14.2 0.1 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Sigma_reg_N PF13800.6 CBY38284.1 - 0.05 13.9 0.7 2.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Ribosomal_S30 PF04758.14 CBY38285.1 - 3e-29 101.0 8.5 5.4e-29 100.2 8.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L4 PF00573.22 CBY38286.1 - 1e-37 129.7 1.1 1.6e-37 129.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBY38286.1 - 7.4e-26 90.0 4.8 7.4e-26 90.0 4.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PGDH_C PF16896.5 CBY38286.1 - 0.024 14.6 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term LIAS_N PF16881.5 CBY38287.1 - 1e-25 90.2 0.0 2.8e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CBY38287.1 - 3.5e-14 53.5 0.0 5.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily OCRE PF17780.1 CBY38288.1 - 9.5e-07 28.8 0.2 1.8e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 OCRE domain Yop-YscD_cpl PF16697.5 CBY38288.1 - 0.044 14.1 0.2 1.4 9.2 0.1 2.4 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Astro_capsid_p PF12226.8 CBY38288.1 - 0.41 9.7 3.2 0.61 9.2 3.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-C3HC4_3 PF13920.6 CBY38289.1 - 2.6e-05 24.0 13.0 2.6e-05 24.0 13.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 CBY38289.1 - 0.0064 16.7 33.5 0.02 15.1 10.9 2.9 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) zf-C3HC4 PF00097.25 CBY38289.1 - 0.013 15.3 17.7 0.018 14.9 15.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY38289.1 - 0.015 15.1 16.4 0.015 15.1 16.4 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY38289.1 - 0.023 15.0 17.8 0.027 14.8 15.7 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 CBY38289.1 - 0.39 10.9 17.2 1.3 9.3 17.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TEA PF01285.18 CBY38289.1 - 0.52 10.4 3.3 0.33 11.1 0.5 2.1 2 1 0 2 2 2 0 TEA/ATTS domain zf-RING_6 PF14835.6 CBY38289.1 - 2.2 8.2 14.2 0.053 13.4 7.7 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CBY38289.1 - 3.9 7.7 18.8 1 9.5 14.6 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 TRAF_BIRC3_bd PF16673.5 CBY38289.1 - 7.8 6.4 17.0 0.35 10.7 2.5 3.9 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain DDOST_48kD PF03345.14 CBY38290.1 - 1.2e-111 373.6 3.4 1.4e-111 373.3 3.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 CBY38290.1 - 8.7e-08 31.0 0.4 1.4e-07 30.3 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) Rep_fac_C PF08542.11 CBY38291.1 - 1.1e-20 73.8 0.1 4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY38291.1 - 5.8e-15 55.4 0.1 2.1e-12 47.1 0.2 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CBY38291.1 - 6.6e-14 52.5 0.1 1.1e-13 51.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CBY38291.1 - 4.8e-08 33.0 0.1 1e-07 32.0 0.0 1.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CBY38291.1 - 5.8e-08 32.9 0.0 2.5e-07 30.8 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CBY38291.1 - 6.8e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY38291.1 - 1.9e-05 25.0 0.2 0.012 15.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY38291.1 - 1.9e-05 25.1 0.0 0.0011 19.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CBY38291.1 - 8.9e-05 22.0 0.0 0.0016 17.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBY38291.1 - 0.00026 21.4 0.1 0.00062 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY38291.1 - 0.00028 20.7 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CBY38291.1 - 0.00046 19.7 0.0 0.62 9.4 0.0 2.3 1 1 0 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 CBY38291.1 - 0.00058 19.6 0.0 0.0026 17.5 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CBY38291.1 - 0.00069 19.5 0.1 0.001 19.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CBY38291.1 - 0.00076 19.1 0.0 0.0024 17.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CBY38291.1 - 0.0012 19.1 0.0 0.0039 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 CBY38291.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBY38291.1 - 0.0018 18.8 0.0 0.0075 16.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CBY38291.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY38291.1 - 0.004 17.0 0.3 0.44 10.3 0.0 2.8 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_28 PF13521.6 CBY38291.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBY38291.1 - 0.023 14.4 0.1 0.065 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY38291.1 - 0.031 14.6 0.0 0.094 13.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DNA_pol3_delta PF06144.13 CBY38291.1 - 0.034 13.9 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 CBY38291.1 - 0.035 13.6 0.0 0.074 12.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region APG17 PF04108.12 CBY38291.1 - 0.037 13.1 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 NTPase_1 PF03266.15 CBY38291.1 - 0.054 13.4 0.4 0.38 10.6 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_3 PF07726.11 CBY38291.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 CBY38292.1 - 2.4e-07 30.0 14.5 3.3e-07 29.6 14.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY38292.1 - 0.0053 15.7 5.9 0.0053 15.7 5.9 1.3 1 1 0 1 1 1 1 MFS_1 like family DUF4922 PF16269.5 CBY38295.1 - 2.9e-05 23.9 0.0 0.0063 16.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4922) ATP_transf PF09830.9 CBY38295.1 - 0.034 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 ATP adenylyltransferase DcpS_C PF11969.8 CBY38295.1 - 0.084 13.4 3.1 11 6.6 0.1 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBY38295.1 - 0.26 12.1 6.0 3.7 8.3 0.6 3.4 2 1 0 2 2 2 0 HIT domain UcrQ PF02939.16 CBY38299.1 - 8.3e-09 35.3 1.2 1.1e-08 34.9 1.2 1.4 1 1 0 1 1 1 1 UcrQ family Ribosomal_S3_C PF00189.20 CBY38302.1 - 2.1e-24 85.8 1.6 1.9e-23 82.8 1.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBY38302.1 - 5e-11 42.3 0.4 9.6e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 CBY38302.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus PTR2 PF00854.21 CBY38303.1 - 1e-67 228.7 13.5 3.5e-46 157.8 4.3 2.1 1 1 1 2 2 2 2 POT family Cu-oxidase_3 PF07732.15 CBY38304.1 - 2.7e-36 124.2 2.5 6.1e-36 123.0 0.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY38304.1 - 4.7e-21 74.9 2.2 4.7e-21 74.9 2.2 3.2 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CBY38304.1 - 0.13 12.4 0.4 1.8 8.7 0.1 2.8 2 1 0 2 2 2 0 Multicopper oxidase DUF2089 PF09862.9 CBY38306.1 - 0.14 12.2 5.1 0.12 12.4 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) DUF4407 PF14362.6 CBY38306.1 - 0.23 10.8 10.3 0.42 9.9 10.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 CBY38306.1 - 0.29 10.7 9.0 0.33 10.5 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.15 CBY38306.1 - 0.79 9.2 5.8 1 8.9 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 CBY38306.1 - 1.7 7.8 5.5 2.5 7.3 5.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 CBY38306.1 - 7.5 7.2 10.1 1.8 9.2 4.3 2.7 1 1 1 2 2 2 0 SlyX Ras PF00071.22 CBY38307.1 - 2.7e-53 179.9 0.0 3.2e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY38307.1 - 7.5e-23 81.0 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY38307.1 - 6.1e-06 25.8 0.0 9.6e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CBY38307.1 - 0.047 13.4 0.1 0.89 9.3 0.1 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Nup35_RRM_2 PF14605.6 CBY38308.1 - 0.0021 18.0 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY38308.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBY38308.1 - 0.033 14.0 0.1 0.071 12.9 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD15 PF18828.1 CBY38308.1 - 0.057 13.3 0.5 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 FERM_M PF00373.18 CBY38309.1 - 3.3e-16 59.7 0.6 9.9e-16 58.2 0.1 1.9 2 0 0 2 2 2 1 FERM central domain FERM_C PF09380.10 CBY38309.1 - 4.9e-14 52.5 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 FERM C-terminal PH-like domain FERM_N PF09379.10 CBY38309.1 - 1.4e-11 44.2 0.6 1.1e-10 41.3 0.3 2.3 2 0 0 2 2 2 1 FERM N-terminal domain EVI2A PF05399.11 CBY38310.1 - 5.8 6.4 9.7 3.8 7.0 5.2 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Ammonium_transp PF00909.21 CBY38312.1 - 5.7e-73 245.9 23.2 1.5e-72 244.5 23.2 1.5 1 1 0 1 1 1 1 Ammonium Transporter Family LETM1 PF07766.13 CBY38313.1 - 0.38 10.0 4.4 0.37 10.1 4.4 1.1 1 0 0 1 1 1 0 LETM1-like protein PPL5 PF18168.1 CBY38313.1 - 0.44 9.8 6.1 0.49 9.6 6.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 CBY38313.1 - 0.44 10.0 6.4 0.54 9.7 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_Rpc4 PF05132.14 CBY38313.1 - 0.6 10.5 6.0 0.67 10.4 6.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4562 PF15123.6 CBY38315.1 - 1.3e-09 38.0 0.0 1.3e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4562) INPP5B_PH PF16776.5 CBY38316.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain TMEM154 PF15102.6 CBY38317.1 - 0.0046 16.9 0.1 0.0099 15.8 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CBY38317.1 - 0.024 15.5 0.0 0.057 14.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PspB PF06667.12 CBY38317.1 - 0.068 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF2986 PF11661.8 CBY38317.1 - 0.089 13.3 0.8 0.34 11.5 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF621 PF04789.15 CBY38317.1 - 0.33 10.1 1.5 0.52 9.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF621) SCIMP PF15050.6 CBY38317.1 - 2.5 8.6 8.9 0.44 11.0 4.4 2.0 2 1 1 3 3 3 0 SCIMP protein WD40 PF00400.32 CBY38318.1 - 2.9e-09 37.4 6.6 0.00013 22.6 0.6 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY38318.1 - 0.0018 18.6 0.2 0.65 10.3 0.1 3.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain FGGY_N PF00370.21 CBY38318.1 - 0.015 14.9 0.5 0.025 14.1 0.5 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PALB2_WD40 PF16756.5 CBY38318.1 - 0.037 13.0 0.2 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Proteasom_Rpn13 PF04683.13 CBY38318.1 - 0.072 13.6 2.2 18 6.0 0.1 3.1 3 0 0 3 3 3 0 Proteasome complex subunit Rpn13 ubiquitin receptor fn3 PF00041.21 CBY38318.1 - 0.2 12.0 1.0 0.78 10.1 0.1 2.4 2 0 0 2 2 2 0 Fibronectin type III domain DUF1348 PF07080.11 CBY38319.1 - 0.052 13.5 0.8 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) Dus PF01207.17 CBY38320.1 - 1.2e-37 129.7 0.0 1.4e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) AROS PF15684.5 CBY38321.1 - 0.092 13.3 23.1 0.61 10.6 23.1 1.9 1 1 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 DNA_topoisoIV PF00521.20 CBY38323.1 - 2.9e-116 388.8 0.5 2.9e-116 388.8 0.5 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBY38323.1 - 8.8e-40 135.9 4.2 1.1e-39 135.6 1.6 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBY38323.1 - 4.8e-27 94.5 2.3 1.2e-26 93.3 2.3 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBY38323.1 - 3.3e-13 50.1 0.1 1.3e-12 48.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBY38323.1 - 9.4e-08 32.2 0.0 5.9e-07 29.7 0.0 2.5 1 0 0 1 1 1 1 Toprim domain DDE_Tnp_1 PF01609.21 CBY38323.1 - 0.013 15.1 1.1 0.041 13.5 0.7 2.0 2 0 0 2 2 2 0 Transposase DDE domain ABC_tran_CTD PF16326.5 CBY38323.1 - 3.2 8.1 8.8 0.45 10.8 2.4 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain TUDOR PF00567.24 CBY38325.1 - 8.5e-11 41.9 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain PI3_PI4_kinase PF00454.27 CBY38326.1 - 1.8e-26 93.5 0.1 2.9e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBY38326.1 - 0.0047 16.3 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Pkinase PF00069.25 CBY38328.1 - 4.9e-38 131.0 0.1 5.8e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38328.1 - 3.8e-19 69.0 0.0 4.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY38328.1 - 4.8e-07 29.4 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY38328.1 - 1.9e-05 23.8 0.6 2.3e-05 23.5 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY38328.1 - 5.2e-05 22.2 0.0 6.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY38328.1 - 6.7e-05 22.6 1.7 9e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY38328.1 - 0.00021 21.3 0.5 0.00034 20.6 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY38328.1 - 0.00078 18.8 0.9 0.0011 18.3 0.9 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-PolyVal PF18762.1 CBY38328.1 - 0.07 13.1 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 CBY38328.1 - 0.1 12.2 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SPATA48 PF15073.6 CBY38330.1 - 1.5e-06 28.5 0.9 3.5e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 FAD_binding_7 PF03441.14 CBY38333.1 - 2.5e-28 98.9 0.6 4.1e-28 98.3 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBY38333.1 - 4.3e-26 91.9 0.0 8.3e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Glyco_hydro_31 PF01055.26 CBY38337.1 - 2.1e-34 119.5 4.3 3.4e-34 118.8 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 EGF_CA PF07645.15 CBY38338.1 - 2.2e-77 255.0 232.6 5.2e-09 36.2 8.7 15.1 12 2 3 15 15 15 12 Calcium-binding EGF domain cEGF PF12662.7 CBY38338.1 - 6.9e-41 137.8 126.5 1.9e-10 40.4 3.0 13.2 12 0 0 12 12 12 10 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY38338.1 - 1.5e-37 127.5 178.3 7.4e-09 35.7 11.8 15.1 11 3 4 15 15 14 10 EGF domain FXa_inhibition PF14670.6 CBY38338.1 - 8.2e-16 58.0 171.7 2.6e-08 34.0 7.3 14.1 8 4 6 14 14 13 11 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY38338.1 - 5.6e-12 45.7 177.3 0.0026 18.0 6.4 15.7 14 2 1 15 15 14 8 EGF-like domain I-set PF07679.16 CBY38338.1 - 6.2e-09 35.8 0.4 1.8e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY38338.1 - 8.2e-09 36.0 0.0 8.2e-09 36.0 0.0 2.7 4 0 0 4 4 3 1 Immunoglobulin domain V-set PF07686.17 CBY38338.1 - 8.9e-08 32.3 3.0 9.5e-08 32.2 0.0 2.6 3 0 0 3 3 3 1 Immunoglobulin V-set domain Plasmod_Pvs28 PF06247.11 CBY38338.1 - 2.3e-07 31.0 160.1 0.0077 16.5 2.5 13.9 13 0 0 13 13 13 8 Pvs28 EGF domain ig PF00047.25 CBY38338.1 - 1.3e-05 25.2 0.0 1.3e-05 25.2 0.0 2.4 3 0 0 3 3 1 1 Immunoglobulin domain hEGF PF12661.7 CBY38338.1 - 6e-05 23.5 159.8 0.0015 19.1 2.5 16.3 17 0 0 17 17 16 8 Human growth factor-like EGF Ig_2 PF13895.6 CBY38338.1 - 9.5e-05 22.7 0.0 9.5e-05 22.7 0.0 3.6 3 1 0 3 3 3 1 Immunoglobulin domain EGF_MSP1_1 PF12946.7 CBY38338.1 - 0.00099 19.1 8.3 0.00099 19.1 8.3 14.2 14 0 0 14 14 14 6 MSP1 EGF domain 1 Transket_pyr PF02779.24 CBY38341.1 - 3.3e-44 150.7 0.2 4.5e-44 150.2 0.2 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY38341.1 - 3.8e-39 133.4 0.0 8.2e-39 132.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBY38341.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Acyl-CoA_dh_N PF02771.16 CBY38341.1 - 0.16 12.7 0.4 0.44 11.2 0.4 1.9 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain zf-C3HC4_3 PF13920.6 CBY38342.1 - 6.4e-06 25.9 5.7 8.3e-06 25.6 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY38342.1 - 3.7e-05 24.0 6.8 4.8e-05 23.6 6.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBY38342.1 - 8.5e-05 22.4 6.5 0.00011 22.1 6.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY38342.1 - 0.00069 19.4 5.3 0.00093 19.0 5.3 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY38342.1 - 0.00094 18.9 5.7 0.0012 18.6 5.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CBY38342.1 - 0.0015 18.3 6.8 0.0021 17.9 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY38342.1 - 0.0018 18.1 7.3 0.0031 17.4 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY38342.1 - 0.023 14.8 5.7 0.22 11.7 6.6 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CBY38342.1 - 0.027 13.9 1.2 0.023 14.1 1.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2256 PF10013.9 CBY38342.1 - 0.079 13.1 2.7 0.079 13.1 2.7 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 CBY38342.1 - 0.39 11.2 6.5 13 6.5 6.5 2.4 1 1 0 1 1 1 0 Zinc-finger double domain T4_deiodinase PF00837.17 CBY38343.1 - 9.4e-25 87.3 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Iodothyronine deiodinase zf-C4 PF00105.18 CBY38344.1 - 3.6e-16 59.4 10.1 7.2e-16 58.4 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY38344.1 - 0.072 12.6 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CBY38344.1 - 0.082 13.0 1.9 0.21 11.7 1.9 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Ldl_recept_a PF00057.18 CBY38346.1 - 1.1e-08 35.1 15.2 1.3e-07 31.7 6.1 2.8 2 1 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH-like PF12999.7 CBY38346.1 - 0.0028 17.5 7.4 0.0044 16.8 7.4 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like Cas_Csy4 PF09618.10 CBY38346.1 - 0.071 13.2 0.6 0.1 12.7 0.6 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) MRP-S35 PF10246.9 CBY38347.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PCNP PF15473.6 CBY38349.1 - 1.6 9.4 7.8 0.16 12.7 2.6 2.0 2 1 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family SNAPc_SNAP43 PF09808.9 CBY38353.1 - 2.5e-20 73.3 2.1 2.7e-20 73.1 2.1 1.0 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Herpes_IE68 PF02479.16 CBY38353.1 - 0.093 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus immediate early protein IL2 PF00715.17 CBY38354.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Interleukin 2 CUB PF00431.20 CBY38355.1 - 6.4e-10 39.3 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 CUB domain TssO PF17561.2 CBY38355.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssO BACK PF07707.15 CBY38356.1 - 3.8e-08 33.4 0.7 3.1e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 CBY38356.1 - 2.8e-07 30.8 0.0 1.2e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain FCH PF00611.23 CBY38358.1 - 2.3e-08 34.2 0.0 1.2e-07 32.0 0.0 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CBY38358.1 - 0.07 12.8 0.1 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 SH3 domain DUF725 PF05267.12 CBY38358.1 - 2 8.4 17.9 0.35 10.9 0.7 4.7 4 1 0 5 5 5 0 Protein of unknown function (DUF725) RP-C_C PF11800.8 CBY38358.1 - 4.1 7.4 12.0 8.2 6.5 0.4 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region EI24 PF07264.11 CBY38359.1 - 3.1e-19 69.9 11.1 4.3e-19 69.4 11.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Rad51 PF08423.11 CBY38360.1 - 4.3e-115 383.3 0.1 6.8e-115 382.7 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY38360.1 - 3.3e-10 39.9 0.2 5e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBY38360.1 - 4.7e-07 29.6 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY38360.1 - 8.6e-06 25.3 0.8 4.4e-05 22.9 0.8 2.1 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY38360.1 - 0.0051 17.4 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 CBY38360.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain GvpD PF07088.11 CBY38360.1 - 0.14 10.7 0.0 0.3 9.6 0.0 1.5 1 0 0 1 1 1 0 GvpD gas vesicle protein Pkinase PF00069.25 CBY38361.1 - 3.5e-76 256.0 0.0 4e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38361.1 - 1.6e-35 122.6 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY38361.1 - 7.1e-06 25.2 0.0 6.9e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY38361.1 - 8.4e-06 25.3 0.0 3.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CBY38361.1 - 0.0015 18.5 0.1 0.0057 16.6 0.1 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY38361.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CBY38362.1 - 7.2e-30 104.2 0.0 1.1e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38362.1 - 4.9e-25 88.3 0.0 9.1e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY38362.1 - 0.021 13.6 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBY38364.1 - 6.3e-07 29.0 0.1 7e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38364.1 - 2.8e-05 23.5 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Forkhead PF00250.18 CBY38365.1 - 3.9e-31 107.1 0.1 5.7e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 Forkhead domain Trypsin PF00089.26 CBY38366.1 - 1e-39 136.7 0.2 2.3e-38 132.2 0.2 2.2 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY38366.1 - 5.7e-05 24.1 0.0 0.00013 22.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY38366.1 - 0.0025 18.2 0.4 0.0048 17.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin PF00089.26 CBY38367.1 - 5.5e-39 134.3 0.2 8.5e-39 133.6 0.2 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY38367.1 - 0.0012 19.7 0.0 0.0027 18.6 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Methyltranf_PUA PF13636.6 CBY38367.1 - 0.14 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF P4Ha_N PF08336.11 CBY38368.1 - 3.3e-20 72.5 0.2 5.6e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy_3 PF13640.6 CBY38368.1 - 8.8e-13 49.0 0.0 1.9e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBY38368.1 - 0.00026 21.4 0.0 0.00055 20.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Not3 PF04065.15 CBY38368.1 - 0.041 13.3 4.6 0.072 12.5 4.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Asp5 PF17000.5 CBY38368.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 AAA_6 PF12774.7 CBY38369.1 - 3.8e-153 509.2 0.0 6.3e-153 508.5 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBY38369.1 - 8.4e-149 496.0 20.1 4e-101 339.0 6.3 3.9 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 CBY38369.1 - 6.3e-08 32.7 0.0 0.06 13.3 0.0 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY38369.1 - 0.00016 22.1 1.2 0.16 12.4 0.1 4.5 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY38369.1 - 0.002 18.7 0.0 0.55 10.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain SQS_PSY PF00494.19 CBY38369.1 - 0.037 13.5 0.1 2.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Squalene/phytoene synthase Vert_IL3-reg_TF PF06529.11 CBY38369.1 - 0.2 10.7 0.1 0.34 10.0 0.1 1.2 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor DUF4210 PF13915.6 CBY38370.1 - 4.8e-15 55.9 0.1 1.1e-12 48.3 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CBY38370.1 - 2.9e-14 53.0 0.1 6.6e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis mIF3 PF14877.6 CBY38372.1 - 0.15 11.7 0.5 6.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial translation initiation factor PVL_ORF50 PF07768.11 CBY38374.1 - 0.33 11.3 0.2 0.33 11.3 0.2 2.6 1 1 2 3 3 3 0 PVL ORF-50-like family GDPD PF03009.17 CBY38375.1 - 1e-33 117.2 0.2 1.3e-33 116.9 0.2 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2326 PF10088.9 CBY38375.1 - 0.018 14.8 0.6 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) ASC PF00858.24 CBY38376.1 - 4e-53 181.0 14.3 5.9e-53 180.4 14.3 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel EGF PF00008.27 CBY38378.1 - 5.1e-12 45.9 23.6 4e-07 30.2 5.2 5.1 4 2 1 5 5 5 2 EGF-like domain Astacin PF01400.24 CBY38378.1 - 3.1e-08 33.5 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Ldl_recept_a PF00057.18 CBY38378.1 - 5.5e-07 29.7 27.9 1.6e-05 25.0 16.3 5.1 5 2 0 5 5 5 2 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY38378.1 - 1.3e-05 25.7 16.2 0.00047 20.7 2.2 5.9 7 0 0 7 7 7 2 Human growth factor-like EGF EGF_2 PF07974.13 CBY38378.1 - 0.025 15.0 13.5 0.025 15.0 13.5 4.2 3 1 0 3 3 3 0 EGF-like domain SMN PF06003.12 CBY38379.1 - 0.3 10.3 6.5 0.58 9.4 6.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ferlin_C PF16165.5 CBY38379.1 - 0.44 10.5 2.4 0.69 9.8 2.4 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Med19 PF10278.9 CBY38379.1 - 2.4 8.1 10.1 3.7 7.4 10.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MA3 PF02847.17 CBY38380.1 - 3.9e-34 117.0 1.5 2.1e-20 72.8 0.3 2.2 2 0 0 2 2 2 2 MA3 domain PP2C PF00481.21 CBY38382.1 - 6e-57 193.2 0.0 8.2e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBY38382.1 - 4.5e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C CARD_2 PF16739.5 CBY38382.1 - 0.18 11.8 0.1 0.41 10.7 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain AMP-binding PF00501.28 CBY38384.1 - 1.4e-26 93.1 0.0 4e-14 52.1 0.0 3.7 3 1 0 3 3 3 3 AMP-binding enzyme FF PF01846.19 CBY38386.1 - 4.8e-38 129.1 47.7 8.6e-12 45.1 5.3 6.4 6 0 0 6 6 6 5 FF domain WW PF00397.26 CBY38386.1 - 3.4e-05 23.8 0.7 8.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 WW domain RhoGAP-FF1 PF16512.5 CBY38386.1 - 6.9e-05 23.5 20.3 0.00026 21.6 1.5 4.6 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain PWWP PF00855.17 CBY38387.1 - 6e-13 49.0 2.5 9.5e-13 48.4 0.7 2.1 1 1 1 2 2 2 1 PWWP domain bZIP_1 PF00170.21 CBY38388.1 - 0.00019 21.5 19.9 0.00037 20.5 19.9 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CBY38388.1 - 0.00036 21.0 13.1 0.00061 20.3 13.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CBY38388.1 - 0.0026 17.8 21.0 0.013 15.5 21.0 2.0 1 1 0 1 1 1 1 Basic region leucine zipper Cortex-I_coil PF09304.10 CBY38388.1 - 0.014 15.6 8.6 0.02 15.1 8.6 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil FlaC_arch PF05377.11 CBY38388.1 - 0.016 15.6 5.5 0.03 14.7 5.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SHE3 PF17078.5 CBY38388.1 - 0.026 14.3 8.4 0.039 13.7 8.4 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 RNA_pol_Rpb6 PF01192.22 CBY38388.1 - 0.12 12.4 4.8 0.26 11.3 4.3 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb6 V_ATPase_I PF01496.19 CBY38388.1 - 0.14 10.0 3.8 0.15 9.9 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 CBY38388.1 - 0.15 12.5 6.9 0.16 12.5 6.9 1.1 1 0 0 1 1 1 0 AAA domain Goodbye PF17109.5 CBY38388.1 - 0.3 11.5 4.3 0.42 11.1 4.3 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Pox_A_type_inc PF04508.12 CBY38388.1 - 0.35 10.8 0.1 0.35 10.8 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 CBY38388.1 - 0.63 9.1 7.3 0.67 9.0 7.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54_57_C PF18570.1 CBY38388.1 - 1.9 8.2 11.0 2.7 7.7 2.9 2.4 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain TMPIT PF07851.13 CBY38388.1 - 7.4 5.7 6.7 9.6 5.3 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein ASC PF00858.24 CBY38389.1 - 2.1e-93 313.7 2.5 3.1e-93 313.2 2.5 1.2 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Ets PF00178.22 CBY38390.1 - 1.2e-36 125.0 1.9 2e-36 124.3 1.9 1.3 1 0 0 1 1 1 1 Ets-domain RNA_pol_Rpc34 PF05158.12 CBY38390.1 - 0.12 11.8 2.7 0.12 11.8 1.8 1.5 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit Acyl-CoA_dh_1 PF00441.24 CBY38391.1 - 1.9e-38 132.0 2.8 3e-38 131.4 2.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY38391.1 - 1.1e-23 83.3 0.0 2.2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY38391.1 - 1.3e-20 74.1 0.0 4.5e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY38391.1 - 4.3e-15 56.2 0.3 5.9e-15 55.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF905 PF06006.12 CBY38392.1 - 0.03 14.3 0.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Piwi PF02171.17 CBY38393.1 - 6.4e-28 97.9 0.7 1.2e-27 96.9 0.7 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY38393.1 - 3.6e-10 39.8 0.1 8.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CBY38393.1 - 0.00035 20.8 0.0 0.00095 19.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PIH1 PF08190.12 CBY38394.1 - 1.2e-25 89.9 1.2 1.5e-25 89.6 1.2 1.1 1 0 0 1 1 1 1 PIH1 N-terminal domain DUF5383 PF17355.2 CBY38394.1 - 0.053 13.9 3.1 0.085 13.2 3.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Proteasome PF00227.26 CBY38396.1 - 2.2e-33 115.3 0.0 2.8e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBY38396.1 - 1.5e-13 50.1 0.0 2.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-RING_2 PF13639.6 CBY38397.1 - 1.1e-09 38.4 3.8 1.8e-09 37.7 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY38397.1 - 2.3e-09 36.9 3.6 3.9e-09 36.2 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY38397.1 - 1.1e-08 35.2 1.5 2.5e-08 34.1 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBY38397.1 - 3.2e-07 30.1 3.6 5.3e-07 29.4 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY38397.1 - 5.7e-07 29.5 2.9 1.2e-06 28.4 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CBY38397.1 - 4.8e-06 26.1 2.8 8.2e-06 25.4 2.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBY38397.1 - 0.00034 20.3 5.0 0.00066 19.4 5.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY38397.1 - 0.00068 19.5 2.8 0.0011 18.9 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY38397.1 - 0.0028 17.5 1.9 0.0046 16.8 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CBY38397.1 - 0.0091 15.8 0.8 0.022 14.6 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 CBY38397.1 - 0.017 15.4 2.4 0.028 14.7 2.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 CBY38397.1 - 0.034 14.2 2.2 0.13 12.3 2.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CBY38397.1 - 0.059 13.6 3.0 0.12 12.5 3.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 CBY38397.1 - 0.17 12.0 1.0 0.33 11.1 1.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_6 PF14835.6 CBY38397.1 - 0.17 11.7 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY38397.1 - 0.36 10.7 1.7 0.79 9.6 1.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C4 PF00105.18 CBY38398.1 - 8.1e-28 96.7 20.3 1.5e-27 95.8 20.3 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY38398.1 - 0.00096 18.8 2.5 0.057 13.0 2.5 2.4 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Bgal_small_N PF02929.17 CBY38398.1 - 0.098 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Beta galactosidase small chain Pkinase PF00069.25 CBY38399.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain AAA PF00004.29 CBY38404.1 - 4.7e-41 140.3 0.0 8.1e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY38404.1 - 0.00014 21.9 0.1 0.0008 19.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBY38404.1 - 0.00038 20.6 0.0 0.00091 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBY38404.1 - 0.00042 20.6 0.0 0.025 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY38404.1 - 0.0012 19.2 0.1 0.058 13.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY38404.1 - 0.0022 17.2 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY38404.1 - 0.0034 17.1 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY38404.1 - 0.0045 17.2 0.0 0.0077 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY38404.1 - 0.018 14.5 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY38404.1 - 0.02 15.3 0.0 0.1 13.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CBY38404.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBY38404.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CBY38404.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CBY38404.1 - 0.089 12.5 0.1 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CBY38404.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY38404.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBY38404.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBY38404.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CBY38404.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sec8_exocyst PF04048.14 CBY38405.1 - 9.4e-12 45.0 0.1 9.4e-12 45.0 0.1 4.7 5 2 0 5 5 5 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CBY38405.1 - 0.0034 16.7 8.4 0.0034 16.7 8.4 2.8 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex ALMT PF11744.8 CBY38405.1 - 0.049 12.5 5.3 0.019 13.8 1.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter GLE1 PF07817.13 CBY38405.1 - 0.098 11.9 1.3 0.82 8.8 0.0 3.0 4 0 0 4 4 4 0 GLE1-like protein BLOC1_2 PF10046.9 CBY38405.1 - 0.15 12.4 0.0 0.15 12.4 0.0 4.0 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps4_C PF09336.10 CBY38406.1 - 0.28 11.2 3.5 3.2 7.8 0.6 3.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain CLTH PF10607.9 CBY38407.1 - 2.2e-24 86.0 0.8 3.1e-24 85.5 0.8 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain B9-C2 PF07162.11 CBY38408.1 - 2.1e-44 151.7 0.0 2.4e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4457 PF14652.6 CBY38409.1 - 3.6e-27 95.5 1.5 1.2e-13 51.0 0.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4457) FPL PF09758.9 CBY38410.1 - 1.5e-59 200.2 7.3 1.5e-59 200.2 7.3 2.4 3 0 0 3 3 3 1 Uncharacterised conserved protein zf-C2H2 PF00096.26 CBY38412.1 - 0.00024 21.4 10.5 0.00067 20.0 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY38412.1 - 0.0047 17.6 1.2 0.0047 17.6 1.2 3.3 2 1 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY38412.1 - 4.9 7.8 15.2 8.3 7.0 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double domain HAT PF02184.16 CBY38413.1 - 5.8e-33 112.5 59.8 1.6e-15 56.8 0.6 13.3 12 3 0 12 12 12 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CBY38413.1 - 2.1e-19 68.5 28.0 0.072 13.9 0.1 12.5 5 4 8 13 13 13 7 Tetratricopeptide repeat Suf PF05843.14 CBY38413.1 - 3.8e-17 63.2 20.6 3.7e-05 23.9 3.3 6.3 1 1 4 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CBY38413.1 - 1.1e-12 48.3 0.0 0.17 12.4 0.1 7.2 4 2 5 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY38413.1 - 1.9e-08 34.1 5.1 0.0096 16.2 0.0 7.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY38413.1 - 2.5e-07 31.2 8.0 5.5 7.7 0.1 7.4 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY38413.1 - 1.3e-05 25.5 17.2 17 6.3 0.1 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY38413.1 - 1.7e-05 24.6 28.2 2.3 8.5 0.7 10.6 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38413.1 - 4.4e-05 23.4 3.5 2.6 8.5 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY38413.1 - 0.00082 19.5 7.7 1.4 9.2 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY38413.1 - 0.00097 19.1 25.4 0.0096 15.9 0.7 6.4 4 2 1 5 5 5 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CBY38413.1 - 0.0016 18.7 11.9 3.5 8.0 0.0 7.1 7 2 2 9 9 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY38413.1 - 0.0032 17.5 7.2 0.94 9.6 0.1 5.4 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 CBY38413.1 - 0.0089 16.1 27.0 0.03 14.4 2.5 7.7 6 4 3 9 9 9 1 U3 small nucleolar RNA-associated protein 6 TPR_MalT PF17874.1 CBY38413.1 - 0.084 12.2 4.6 0.42 9.9 1.0 3.1 3 0 0 3 3 3 0 MalT-like TPR region MIT PF04212.18 CBY38413.1 - 0.098 12.7 6.4 6.6 6.9 0.0 4.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain ZNRF_3_ecto PF18212.1 CBY38413.1 - 0.12 12.4 0.0 1.7 8.7 0.0 3.0 4 0 0 4 4 4 0 ZNRF-3 Ectodomain ANAPC3 PF12895.7 CBY38413.1 - 0.16 12.2 8.1 8.2 6.7 0.1 5.3 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Amnionless PF14828.6 CBY38414.1 - 0.39 9.5 2.2 0.75 8.6 0.0 1.9 1 1 1 2 2 2 0 Amnionless Zona_pellucida PF00100.23 CBY38415.1 - 4.4e-34 118.4 3.7 5.4e-34 118.2 3.7 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Fer4_15 PF13459.6 CBY38415.1 - 0.15 12.8 0.6 1.1 10.0 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF3377 PF11857.8 CBY38415.1 - 0.15 12.0 1.3 0.43 10.5 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) zf-Nse PF11789.8 CBY38416.1 - 3.1e-09 36.5 0.3 4.5e-09 36.0 0.3 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CBY38416.1 - 0.024 14.6 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.20 CBY38416.1 - 0.026 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.21 CBY38416.1 - 0.087 13.1 1.3 0.11 12.7 0.2 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain IFNGR1 PF07140.11 CBY38416.1 - 0.091 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Interferon gamma receptor (IFNGR1) DUF3456 PF11938.8 CBY38417.1 - 0.044 14.3 0.1 0.069 13.7 0.1 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Ribosomal_L30 PF00327.20 CBY38418.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e tRNA-synt_2d PF01409.20 CBY38420.1 - 1.2e-47 162.5 2.9 4.1e-27 95.2 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CBY38420.1 - 3.6e-11 43.3 0.0 7.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain CDC4_D PF16856.5 CBY38422.1 - 0.01 15.7 0.5 0.029 14.2 0.5 1.8 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Csa1 PF06023.12 CBY38422.1 - 0.029 13.7 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Chibby PF14645.6 CBY38422.1 - 0.036 14.5 0.5 0.036 14.5 0.5 2.0 2 0 0 2 2 2 0 Chibby family Staphostatin_B PF09023.10 CBY38423.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Staphostatin B ADAM_CR_2 PF17771.1 CBY38424.1 - 1.8e-11 44.4 7.8 1.8e-11 44.4 7.8 5.1 4 2 2 6 6 6 2 ADAM cysteine-rich domain Reprolysin PF01421.19 CBY38424.1 - 3.6e-10 40.1 0.0 3.6e-10 40.1 0.0 2.0 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease TSP_1 PF00090.19 CBY38424.1 - 2.3e-09 37.3 9.8 2.3e-09 37.3 9.8 6.8 8 0 0 8 8 8 2 Thrombospondin type 1 domain Reprolysin_5 PF13688.6 CBY38424.1 - 0.00069 19.8 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CBY38424.1 - 0.0015 18.4 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CBY38424.1 - 0.011 16.2 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CBY38424.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 CBY38424.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like dsrm PF00035.26 CBY38425.1 - 3.7e-06 27.5 0.0 0.0091 16.7 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif D5_N PF08706.11 CBY38425.1 - 0.14 12.4 3.1 12 6.2 0.6 2.5 1 1 1 2 2 2 0 D5 N terminal like LPMO_10 PF03067.15 CBY38426.1 - 1.3e-34 120.6 0.3 1.3e-34 120.6 0.3 1.9 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY38426.1 - 9.8e-13 48.1 6.7 4e-12 46.1 6.7 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain FSA_C PF10479.9 CBY38426.1 - 1.7 6.7 13.0 2.2 6.3 13.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LPMO_10 PF03067.15 CBY38427.1 - 4.5e-32 112.3 1.1 4.5e-32 112.3 1.1 1.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY38427.1 - 5.4e-12 45.7 6.7 1.8e-11 44.0 6.7 2.0 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Mucin PF01456.17 CBY38427.1 - 0.25 11.3 13.6 0.4 10.7 13.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank_4 PF13637.6 CBY38431.1 - 0.00054 20.5 0.0 0.0018 18.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY38431.1 - 0.0038 17.8 0.0 0.067 13.8 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY38431.1 - 0.021 15.3 0.0 1.6 9.5 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat UBX PF00789.20 CBY38431.1 - 0.056 13.6 0.1 0.29 11.4 0.1 2.3 1 0 0 1 1 1 0 UBX domain AdoMet_dc PF02675.15 CBY38431.1 - 0.16 12.2 1.0 0.86 9.9 0.0 2.6 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase DUF1690 PF07956.11 CBY38431.1 - 0.19 12.2 3.3 0.42 11.0 3.3 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Adaptin_N PF01602.20 CBY38432.1 - 7.1e-67 226.1 9.5 7.1e-67 226.1 9.5 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CBY38432.1 - 5.9e-08 32.9 5.2 0.00075 19.6 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 AP3D1 PF06375.11 CBY38432.1 - 1.5e-07 31.8 23.1 7.3e-07 29.6 8.3 2.9 2 0 0 2 2 2 2 AP-3 complex subunit delta-1 HEAT PF02985.22 CBY38432.1 - 4.9e-05 23.2 0.9 0.19 12.1 0.0 3.6 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 CBY38432.1 - 0.00066 19.8 1.8 1 9.6 0.6 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 AP4E_app_platf PF14807.6 CBY38432.1 - 0.0029 17.9 0.4 0.008 16.5 0.4 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.6 CBY38432.1 - 0.0046 17.3 0.1 4.5 7.7 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats M11L PF11099.8 CBY38432.1 - 0.4 10.9 7.5 1.2 9.4 3.0 3.1 2 1 1 3 3 3 0 Apoptosis regulator M11L like V-ATPase_H_C PF11698.8 CBY38432.1 - 1.2 9.3 4.7 0.86 9.7 0.4 3.1 3 1 0 3 3 3 0 V-ATPase subunit H Kelch_1 PF01344.25 CBY38434.1 - 3e-62 206.0 4.4 3.2e-15 55.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 CBY38434.1 - 8.2e-55 183.8 4.7 1.3e-29 102.7 1.2 2.5 2 0 0 2 2 2 2 BTB/POZ domain Kelch_6 PF13964.6 CBY38434.1 - 4.3e-36 122.0 2.2 7.1e-08 32.5 0.1 6.4 5 1 1 6 6 6 5 Kelch motif BACK PF07707.15 CBY38434.1 - 1e-25 89.8 0.3 2.3e-25 88.6 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch zf-C2H2_2 PF12756.7 CBY38434.1 - 3.1e-23 82.0 0.0 3.1e-23 82.0 0.0 2.4 3 0 0 3 3 2 1 C2H2 type zinc-finger (2 copies) Kelch_2 PF07646.15 CBY38434.1 - 8.2e-18 63.6 6.2 6.7e-06 25.9 0.0 6.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CBY38434.1 - 8.1e-16 57.8 8.1 2.5e-05 24.2 0.0 6.3 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY38434.1 - 1.1e-12 47.9 3.9 0.0029 17.9 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY38434.1 - 1.1e-05 25.3 3.9 5.7 7.1 0.0 5.5 6 0 0 6 6 6 2 Kelch motif DUF3342 PF11822.8 CBY38434.1 - 7.1e-05 22.9 4.2 0.012 15.8 0.7 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3342) Skp1_POZ PF03931.15 CBY38434.1 - 0.0062 16.7 0.1 8.2 6.7 0.0 2.8 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain EpmC PF04315.12 CBY38434.1 - 0.014 15.1 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor P hydroxylase TIP49 PF06068.13 CBY38434.1 - 0.05 12.8 0.1 11 5.1 0.0 2.4 3 0 0 3 3 3 0 TIP49 P-loop domain PQQ_3 PF13570.6 CBY38434.1 - 2.3 8.8 3.7 70 4.1 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain G-alpha PF00503.20 CBY38435.1 - 7.8e-88 295.0 11.4 9.5e-88 294.7 11.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY38435.1 - 3.7e-13 49.3 2.2 9.8e-09 34.9 0.5 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 CBY38435.1 - 0.0017 18.1 0.2 0.0027 17.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CBY38435.1 - 0.0024 18.1 1.0 1.4 9.2 0.4 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY38435.1 - 0.015 15.4 1.4 2.1 8.4 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CBY38435.1 - 0.065 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 CBY38435.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain GEN1_C PF18380.1 CBY38436.1 - 0.02 15.8 0.1 0.038 14.9 0.1 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain IHHNV_capsid PF16530.5 CBY38437.1 - 0.037 13.1 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Kelch_5 PF13854.6 CBY38439.1 - 0.002 18.1 2.6 0.03 14.3 0.0 3.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CBY38439.1 - 0.0048 16.8 1.7 2.4 8.3 0.0 3.8 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBY38439.1 - 1.6 9.1 3.9 11 6.5 0.0 3.5 4 1 1 5 5 5 0 Kelch motif T-box PF00907.22 CBY38441.1 - 9.6e-83 277.0 0.6 1.2e-82 276.7 0.6 1.1 1 0 0 1 1 1 1 T-box Tctex-1 PF03645.13 CBY38442.1 - 4.2e-08 33.3 0.0 4.5e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Phospholip_A2_1 PF00068.19 CBY38443.1 - 1.1e-17 64.5 8.7 1.1e-17 64.5 8.7 1.5 2 0 0 2 2 2 1 Phospholipase A2 DUF3113 PF11310.8 CBY38443.1 - 0.17 11.8 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) BTB_2 PF02214.22 CBY38445.1 - 3.1e-23 81.9 1.0 9.6e-23 80.4 0.5 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 CBY38445.1 - 0.0056 16.8 0.1 0.027 14.6 0.1 2.1 2 1 0 2 2 2 1 BTB/POZ domain MIF4G PF02854.19 CBY38446.1 - 7.9e-08 32.2 0.1 4.7e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain Par3_HAL_N_term PF12053.8 CBY38447.1 - 3.6e-23 81.6 0.5 4.5e-23 81.3 0.5 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins PDZ PF00595.24 CBY38448.1 - 1.4e-26 92.7 0.4 8.6e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY38448.1 - 1e-12 47.7 0.1 2.5e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY38448.1 - 4.7e-10 39.7 0.1 8e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Homeodomain PF00046.29 CBY38449.1 - 1.1e-20 73.1 3.1 2.6e-20 72.0 3.1 1.7 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 CBY38450.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38450.1 - 9.9e-08 31.6 0.0 3e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Creatininase PF02633.14 CBY38450.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase WD40 PF00400.32 CBY38451.1 - 1.1 10.2 4.7 82 4.3 4.7 3.1 1 1 0 1 1 1 0 WD domain, G-beta repeat ubiquitin PF00240.23 CBY38452.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF92 PF01940.16 CBY38453.1 - 3.7e-57 193.5 5.2 1.9e-28 99.5 0.4 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF92 TMEM132D_C PF15706.5 CBY38453.1 - 0.096 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2207 PF09972.9 CBY38453.1 - 0.11 11.3 2.2 0.31 9.7 2.2 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Band_7 PF01145.25 CBY38454.1 - 1.2e-24 87.3 0.5 1.6e-24 86.9 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 CBY38456.1 - 1.3e-60 205.0 0.1 1.6e-60 204.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38456.1 - 1.7e-39 135.7 0.0 2e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY38456.1 - 2.3e-06 26.7 0.0 4.2e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY38456.1 - 7.9e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY38456.1 - 0.00022 20.6 0.3 0.00049 19.5 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY38456.1 - 0.037 14.0 0.0 0.12 12.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family ERAP1_C PF11838.8 CBY38457.1 - 0.018 14.6 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain ArenaCapSnatch PF17296.2 CBY38457.1 - 0.061 12.8 0.1 0.064 12.7 0.1 1.1 1 0 0 1 1 1 0 Arenavirus cap snatching domain DUF4976 PF16347.5 CBY38458.1 - 0.00033 20.9 0.4 0.00054 20.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) KELK PF15796.5 CBY38460.1 - 0.02 15.3 8.9 0.02 15.3 8.9 4.2 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase MMR_HSR1_C PF08438.10 CBY38460.1 - 0.037 14.6 4.9 0.11 13.1 4.9 1.9 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Baculo_p24 PF05073.12 CBY38460.1 - 0.49 10.2 10.8 0.29 10.9 8.3 1.9 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Exonuc_VII_L PF02601.15 CBY38460.1 - 0.73 9.3 16.1 1 8.9 16.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 CBY38460.1 - 7.1 6.4 12.0 2.3 8.0 7.2 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF3450 PF11932.8 CBY38460.1 - 9.5 5.4 23.7 26 4.0 20.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Kelch_1 PF01344.25 CBY38461.1 - 1.3e-07 31.0 0.0 0.00023 20.6 0.0 3.1 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY38461.1 - 1.7e-07 31.2 0.0 3.6e-06 26.9 0.0 2.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY38461.1 - 5.7e-06 26.4 0.0 0.0081 16.4 0.0 2.7 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY38461.1 - 0.00045 20.1 0.0 0.051 13.6 0.0 2.6 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CBY38461.1 - 0.00048 20.3 0.0 0.18 12.1 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain ASH PF15780.5 CBY38462.1 - 2e-35 120.9 24.0 0.0099 16.1 0.0 16.6 15 2 1 16 16 16 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY38462.1 - 2.4e-08 33.9 7.6 2.2 8.3 0.0 9.7 11 0 0 11 11 11 2 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 CBY38462.1 - 3.7e-08 33.2 24.4 1.2 9.0 0.0 12.4 16 1 0 16 16 16 4 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CBY38462.1 - 6.6e-08 32.7 12.7 1 9.7 0.6 9.4 10 0 0 10 10 10 3 Transmembrane protein 131-like DUF5001 PF16392.5 CBY38462.1 - 1.1e-05 25.3 0.6 3.6 7.6 0.0 6.8 7 0 0 7 7 7 1 Ig-like domain PapD-like PF14874.6 CBY38462.1 - 0.00052 20.1 0.0 1.4 9.1 0.0 5.8 7 0 0 7 7 7 1 Flagellar-associated PapD-like Transglut_C PF00927.22 CBY38462.1 - 0.27 11.4 1.1 92 3.3 0.0 5.3 8 0 0 8 8 8 0 Transglutaminase family, C-terminal ig like domain Motile_Sperm PF00635.26 CBY38463.1 - 2.3e-18 66.0 4.8 0.0028 17.5 0.1 9.2 10 0 0 10 10 10 4 MSP (Major sperm protein) domain ASH PF15780.5 CBY38463.1 - 1.1e-17 64.1 5.1 0.0052 17.0 0.1 10.3 8 2 3 11 11 11 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 CBY38463.1 - 3.8e-14 52.5 10.4 0.049 13.7 0.0 10.6 11 2 0 11 11 11 2 Protein of unknown function (DUF1573) Hydin_ADK PF17213.3 CBY38463.1 - 1.9e-12 47.9 0.6 3.7e-12 47.0 0.6 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain PapD-like PF14874.6 CBY38463.1 - 4.2e-08 33.3 0.1 26 5.1 0.0 7.8 8 0 0 8 8 8 0 Flagellar-associated PapD-like TMEM131_like PF12371.8 CBY38463.1 - 0.00088 19.5 6.8 6.4 7.1 0.1 6.7 9 0 0 9 9 9 1 Transmembrane protein 131-like AAA_17 PF13207.6 CBY38463.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CBY38463.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase SoxY PF13501.6 CBY38463.1 - 0.096 12.9 0.1 0.41 10.9 0.1 2.1 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY AAA_28 PF13521.6 CBY38463.1 - 0.1 12.8 0.4 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF5001 PF16392.5 CBY38463.1 - 1.6 8.7 8.8 1e+02 2.9 0.1 5.9 6 1 1 7 7 7 0 Ig-like domain TIMELESS PF04821.14 CBY38464.1 - 1e-19 70.9 0.3 1.4e-19 70.5 0.3 1.2 1 0 0 1 1 1 1 Timeless protein WbqC PF08889.11 CBY38464.1 - 0.0014 18.5 0.1 0.0027 17.6 0.1 1.4 1 1 0 1 1 1 1 WbqC-like protein family LRR_8 PF13855.6 CBY38465.1 - 7.1e-55 182.6 42.7 4.7e-13 48.7 0.2 6.6 3 1 3 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 CBY38465.1 - 3.2e-23 82.1 14.6 3.7e-16 59.2 2.8 3.8 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY38465.1 - 4.6e-18 65.0 55.8 9e-06 25.9 1.6 8.4 1 1 12 13 13 13 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY38465.1 - 9.1e-16 57.8 21.8 5.5e-06 26.0 2.0 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 CBY38465.1 - 1.1e-05 25.3 38.7 0.56 11.0 0.1 11.6 12 0 0 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.6 CBY38465.1 - 0.00016 21.4 32.1 0.96 9.7 0.5 10.1 10 0 0 10 10 10 2 Leucine Rich repeat LRRNT PF01462.18 CBY38465.1 - 0.00016 21.2 2.2 0.00016 21.2 2.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRRCT PF01463.24 CBY38465.1 - 0.0088 16.5 0.0 0.029 14.9 0.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat C-terminal domain p450 PF00067.22 CBY38466.1 - 1.5e-32 113.0 0.0 1.7e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EGF PF00008.27 CBY38468.1 - 0.06 13.7 18.4 1.2 9.5 5.0 3.5 2 1 0 2 2 2 0 EGF-like domain FXa_inhibition PF14670.6 CBY38468.1 - 0.11 12.7 11.2 0.24 11.7 1.4 2.9 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site Ig_2 PF13895.6 CBY38468.1 - 0.14 12.5 0.2 30 5.1 0.1 2.5 2 0 0 2 2 2 0 Immunoglobulin domain Ldh_2 PF02615.14 CBY38471.1 - 1.5e-80 270.9 1.2 1.8e-80 270.6 1.2 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 CBY38472.1 - 0.05 12.7 0.1 0.053 12.7 0.1 1.0 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase DUF5363 PF17320.2 CBY38472.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5363) Phospholip_A2_1 PF00068.19 CBY38473.1 - 1.8e-17 63.8 8.2 1.8e-17 63.8 8.2 1.7 2 0 0 2 2 2 1 Phospholipase A2 VWD PF00094.25 CBY38474.1 - 5.3e-24 85.3 0.8 1.6e-15 57.7 0.5 2.6 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 CBY38474.1 - 1.8e-18 66.7 18.2 1.3e-08 35.2 6.8 3.9 2 0 0 2 2 2 2 C8 domain TIL PF01826.17 CBY38474.1 - 5.6e-06 26.5 26.0 4.7e-05 23.6 8.9 5.5 5 1 0 5 5 5 2 Trypsin Inhibitor like cysteine rich domain OLF PF02191.16 CBY38475.1 - 3.4e-70 236.4 1.0 4.8e-70 235.9 1.0 1.1 1 0 0 1 1 1 1 Olfactomedin-like domain Gal_Lectin PF02140.18 CBY38475.1 - 2.2e-17 63.2 1.6 4.3e-17 62.3 0.9 1.9 2 0 0 2 2 2 1 Galactose binding lectin domain PDZ PF00595.24 CBY38478.1 - 3.5e-86 283.6 3.4 1.6e-13 50.8 0.0 8.9 9 0 0 9 9 9 8 PDZ domain PDZ_6 PF17820.1 CBY38478.1 - 7.6e-85 278.7 15.8 1.9e-12 46.8 0.1 8.3 8 0 0 8 8 8 8 PDZ domain PDZ_2 PF13180.6 CBY38478.1 - 6e-42 141.9 10.6 3.3e-07 30.5 0.0 8.4 8 0 0 8 8 8 7 PDZ domain Tricorn_PDZ PF14685.6 CBY38478.1 - 8.5e-07 28.9 11.1 0.28 11.2 0.0 6.7 7 0 0 7 7 7 3 Tricorn protease PDZ domain Tetraspanin PF00335.20 CBY38478.1 - 0.00017 21.3 2.8 0.00027 20.7 2.8 1.2 1 0 0 1 1 1 1 Tetraspanin family PDZ_4 PF17816.1 CBY38478.1 - 0.00069 20.0 3.6 1.8 9.0 0.0 5.4 5 1 1 6 6 6 1 PDZ domain Zip PF02535.22 CBY38479.1 - 1.8e-19 70.2 15.6 8.6e-19 67.9 3.0 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter MerC PF03203.14 CBY38479.1 - 0.96 9.9 9.0 0.041 14.3 1.9 2.4 2 1 1 3 3 3 0 MerC mercury resistance protein Vps16_C PF04840.12 CBY38480.1 - 1.8e-18 66.7 5.0 1.4e-17 63.7 5.0 1.9 1 1 0 1 1 1 1 Vps16, C-terminal region ECSIT PF06239.11 CBY38481.1 - 5.6e-14 51.8 0.0 1.5e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C PF14784.6 CBY38481.1 - 5.2e-10 39.8 0.0 4.6e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain of the ECSIT protein GRASP55_65 PF04495.14 CBY38482.1 - 7.8e-68 227.1 0.0 4.7e-50 169.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CBY38482.1 - 4.9e-06 26.3 0.0 0.021 14.7 0.0 2.7 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY38482.1 - 0.00065 20.0 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain NRBF2 PF08961.10 CBY38482.1 - 3.1 7.3 9.7 0.66 9.5 0.6 2.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator SNX17_FERM_C PF18116.1 CBY38484.1 - 0.00029 20.9 0.1 0.00075 19.5 0.1 1.7 1 1 0 1 1 1 1 Sorting Nexin 17 FERM C-terminal domain Trypsin PF00089.26 CBY38486.1 - 3.8e-45 154.4 1.5 6.2e-45 153.7 1.5 1.4 1 0 0 1 1 1 1 Trypsin HLH PF00010.26 CBY38487.1 - 1.5e-16 60.0 0.1 1.5e-16 60.0 0.1 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 CBY38487.1 - 0.091 12.5 2.8 0.32 10.7 1.7 2.1 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 Gal_Lectin PF02140.18 CBY38490.1 - 4.8e-15 55.8 3.7 2.9e-07 30.8 0.2 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain Mito_carr PF00153.27 CBY38491.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein OSK PF17182.4 CBY38492.1 - 0.063 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 OSK domain NADH_B2 PF14813.6 CBY38492.1 - 0.25 11.2 5.3 0.081 12.7 1.2 2.3 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 zinc_ribbon_9 PF14369.6 CBY38492.1 - 1.8 8.9 7.3 5.5 7.3 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon ATP-synt_F6 PF05511.11 CBY38493.1 - 3.5e-16 59.4 0.0 4.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 CBY38493.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase complex subunit h DAGK_cat PF00781.24 CBY38495.1 - 2.5e-27 95.0 0.0 3.8e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 CBY38495.1 - 1.8e-09 38.2 0.0 3.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 CBY38495.1 - 0.00025 20.9 18.1 0.00085 19.2 3.4 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 CBY38495.1 - 0.01 15.8 5.6 0.02 14.9 1.0 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid PHD PF00628.29 CBY38495.1 - 0.08 12.9 12.1 0.074 13.0 0.8 3.0 3 0 0 3 3 3 0 PHD-finger PHD_2 PF13831.6 CBY38495.1 - 1.8 8.2 10.1 0.65 9.6 2.6 2.7 2 0 0 2 2 2 0 PHD-finger DAGK_acc PF00609.19 CBY38496.1 - 1.7e-13 51.2 0.0 2.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Strabismus PF06638.11 CBY38497.1 - 1.8e-101 340.3 3.0 2.1e-101 340.1 3.0 1.0 1 0 0 1 1 1 1 Strabismus protein Slx4 PF09494.10 CBY38498.1 - 3.7e-14 52.4 0.5 1.2e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 Slx4 endonuclease SAP PF02037.27 CBY38498.1 - 0.014 15.2 0.4 0.03 14.1 0.4 1.6 1 0 0 1 1 1 0 SAP domain Hydrolase_6 PF13344.6 CBY38499.1 - 7.5e-18 64.5 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SRCR PF00530.18 CBY38500.1 - 9.9e-32 109.4 14.9 1.1e-17 64.4 0.1 4.4 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 CBY38500.1 - 7.5e-10 39.2 6.2 4.1e-05 24.1 0.0 3.8 3 1 1 4 4 4 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 CBY38500.1 - 0.00056 20.4 0.4 0.34 11.5 0.0 3.6 4 0 0 4 4 4 2 Hepsin, SRCR domain SRCR PF00530.18 CBY38501.1 - 6.5e-15 55.4 6.7 6.5e-15 55.4 6.7 2.2 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 CBY38501.1 - 5.2e-08 33.6 1.4 1.4e-07 32.2 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain TSP_1 PF00090.19 CBY38501.1 - 0.016 15.5 8.8 0.016 15.5 8.8 2.6 2 0 0 2 2 2 0 Thrombospondin type 1 domain zf-C4 PF00105.18 CBY38503.1 - 1.2e-29 102.5 14.1 2.2e-29 101.7 14.1 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) ChaC PF04752.12 CBY38503.1 - 0.1 12.7 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 ChaC-like protein Myosin_head PF00063.21 CBY38504.1 - 6.7e-269 893.8 0.0 6.7e-269 893.8 0.0 2.8 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY38504.1 - 1.6e-130 436.9 241.3 2.1e-130 436.5 241.3 1.1 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY38504.1 - 1.9e-07 30.8 3.3 5.7e-07 29.3 3.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.10 CBY38504.1 - 0.0026 17.9 8.3 0.0026 17.9 8.3 12.4 3 3 8 12 12 12 1 Cortexillin I, coiled coil IQ PF00612.27 CBY38504.1 - 0.0054 16.4 1.3 0.57 10.1 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY38504.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 CBY38504.1 - 0.59 10.5 0.0 0.59 10.5 0.0 4.8 4 2 0 4 4 4 0 AAA ATPase domain YqzL PF14006.6 CBY38504.1 - 1.9 8.9 5.7 5.4 7.5 0.0 5.1 2 1 1 3 3 3 0 YqzL-like protein EGF PF00008.27 CBY38505.1 - 1.9e-05 24.8 2.6 1.9e-05 24.8 2.6 3.2 3 0 0 3 3 3 2 EGF-like domain Tom6 PF17112.5 CBY38505.1 - 0.17 11.4 2.3 0.34 10.4 2.3 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal hEGF PF12661.7 CBY38505.1 - 0.21 12.3 13.0 0.22 12.2 1.3 3.7 3 1 0 3 3 3 0 Human growth factor-like EGF Acyl_transf_3 PF01757.22 CBY38506.1 - 8.4e-13 48.1 28.0 8.4e-13 48.1 28.0 1.7 2 0 0 2 2 2 1 Acyltransferase family GAS PF13851.6 CBY38508.1 - 0.012 14.9 61.8 0.27 10.6 7.8 4.6 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3618 PF12277.8 CBY38508.1 - 0.051 13.8 1.9 0.2 12.0 1.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Pox_A_type_inc PF04508.12 CBY38508.1 - 0.31 11.0 11.4 8.1 6.5 0.0 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat FUSC PF04632.12 CBY38508.1 - 1.9 6.9 7.6 2.8 6.4 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 CBY38508.1 - 5.6 7.3 16.1 1.1 9.5 2.3 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) COBRA1 PF06209.13 CBY38509.1 - 0.0014 17.6 0.0 0.0015 17.5 0.0 1.0 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) DUF1192 PF06698.11 CBY38509.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.6 CBY38509.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 IL22 PF14565.6 CBY38509.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Band_7 PF01145.25 CBY38510.1 - 1.9e-14 54.0 7.2 3e-14 53.4 7.2 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CBY38510.1 - 0.039 14.1 3.9 0.072 13.3 3.9 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 YpjP PF14005.6 CBY38510.1 - 0.27 11.3 2.9 1.4 9.0 0.1 2.3 1 1 0 2 2 2 0 YpjP-like protein SNF PF00209.18 CBY38511.1 - 6.2e-167 556.4 29.7 7e-167 556.3 29.7 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Sulfatase PF00884.23 CBY38513.1 - 6e-42 144.1 0.0 3e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Sulfatase Phosphoesterase PF04185.14 CBY38513.1 - 0.00063 19.0 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoesterase family Phosphodiest PF01663.22 CBY38513.1 - 0.0019 17.9 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase ParcG PF10274.9 CBY38514.1 - 1.2e-82 276.5 0.0 1.4e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Pkinase PF00069.25 CBY38515.1 - 2.4e-18 66.5 0.0 2.6e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38515.1 - 5.9e-09 35.6 0.0 6.3e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY38515.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Serinc PF03348.15 CBY38516.1 - 7e-110 367.9 15.1 8.7e-110 367.6 15.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3671 PF12420.8 CBY38516.1 - 7.1 6.8 7.7 2.2e+02 1.9 7.4 2.9 2 2 0 2 2 2 0 Protein of unknown function Lactamase_B PF00753.27 CBY38517.1 - 1.2e-07 32.0 0.9 8.5e-07 29.2 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY38517.1 - 0.00033 20.2 0.0 0.00074 19.1 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBY38517.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain tRNA-synt_1g PF09334.11 CBY38518.1 - 5.2e-77 259.2 1.3 7.1e-75 252.2 1.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBY38518.1 - 1.4e-15 56.6 1.1 4.6e-09 35.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CBY38518.1 - 5.9e-09 35.7 0.1 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CBY38518.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 CBY38518.1 - 0.05 12.5 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) ARS2 PF04959.13 CBY38519.1 - 2.1e-48 165.3 2.8 3.9e-48 164.4 2.8 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 RRM_1 PF00076.22 CBY38519.1 - 0.0015 18.3 0.0 0.0083 15.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LAP1C PF05609.12 CBY38519.1 - 0.17 11.0 4.5 0.25 10.4 4.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 CBY38519.1 - 0.26 9.5 11.9 0.049 11.9 8.5 1.4 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S9 PF00326.21 CBY38520.1 - 1.3e-41 142.4 1.4 2.4e-41 141.6 1.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBY38520.1 - 1.4e-38 132.6 0.4 2.5e-38 131.7 0.4 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 CBY38520.1 - 0.0016 18.4 3.8 0.006 16.5 0.1 3.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 CBY38520.1 - 0.022 14.4 0.9 0.1 12.2 0.2 2.3 2 1 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 CBY38520.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_9 PF14580.6 CBY38521.1 - 0.14 11.7 0.3 0.59 9.6 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat HSP20 PF00011.21 CBY38522.1 - 1.9e-05 24.7 1.0 0.45 10.7 0.1 3.6 2 2 0 2 2 2 2 Hsp20/alpha crystallin family GIDE PF12483.8 CBY38522.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 E3 Ubiquitin ligase HpaP PF09483.10 CBY38522.1 - 0.17 12.1 0.1 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III secretion protein (HpaP) HSP20 PF00011.21 CBY38523.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family pXO2-72 PF17443.2 CBY38524.1 - 0.059 13.6 0.2 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 TMEM151 PF14857.6 CBY38525.1 - 0.034 13.1 1.3 0.037 13.0 0.6 1.3 1 1 0 1 1 1 0 TMEM151 family SAM_1 PF00536.30 CBY38526.1 - 0.12 12.8 0.4 0.48 10.9 0.1 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3188 PF11384.8 CBY38526.1 - 0.19 11.4 0.1 0.51 10.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DAGK_cat PF00781.24 CBY38527.1 - 2.7e-24 85.2 0.2 4.2e-24 84.6 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Stathmin PF00836.19 CBY38528.1 - 3.8e-10 39.8 4.1 4.1e-10 39.7 4.1 1.0 1 0 0 1 1 1 1 Stathmin family Sulfotransfer_4 PF17784.1 CBY38529.1 - 3.4e-41 141.4 0.0 4.8e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Snapin_Pallidin PF14712.6 CBY38530.1 - 6.6e-07 29.7 23.9 0.00015 22.1 0.6 7.6 4 3 2 7 7 7 1 Snapin/Pallidin Spc7 PF08317.11 CBY38530.1 - 1.4e-06 27.4 49.0 0.0035 16.3 6.7 5.9 2 2 3 6 6 6 4 Spc7 kinetochore protein DUF1664 PF07889.12 CBY38530.1 - 3.3e-05 23.9 43.8 0.64 10.1 0.8 8.1 1 1 2 7 7 7 3 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBY38530.1 - 7.4e-05 22.8 40.0 0.14 12.2 3.8 7.3 3 3 3 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus C1q PF00386.21 CBY38530.1 - 0.0001 22.5 0.1 0.00031 21.0 0.1 1.9 1 0 0 1 1 1 1 C1q domain DUF4407 PF14362.6 CBY38530.1 - 0.0013 18.2 33.7 0.1 11.9 2.6 4.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CBY38530.1 - 0.0014 19.0 39.1 0.0071 16.8 1.5 8.6 6 2 2 8 8 8 2 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 CBY38530.1 - 0.0018 18.3 9.8 0.0018 18.3 9.8 7.4 2 2 6 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 CBY38530.1 - 0.0036 17.5 35.1 1.7 8.9 0.2 8.4 4 4 5 9 9 9 2 Bacterial protein of unknown function (DUF948) CAP_N PF01213.19 CBY38530.1 - 0.0041 16.7 5.0 0.0041 16.7 5.0 3.7 4 0 0 4 4 4 1 Adenylate cyclase associated (CAP) N terminal DUF5082 PF16888.5 CBY38530.1 - 0.0066 16.7 3.6 0.0066 16.7 3.6 7.4 2 2 7 9 9 9 1 Domain of unknown function (DUF5082) ATG16 PF08614.11 CBY38530.1 - 0.0085 16.3 9.9 0.0085 16.3 9.9 5.4 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) FliJ PF02050.16 CBY38530.1 - 0.012 15.8 0.1 0.012 15.8 0.1 5.7 4 3 1 5 5 5 0 Flagellar FliJ protein BclA_C PF18573.1 CBY38530.1 - 0.017 15.1 0.5 0.045 13.6 0.5 1.7 1 0 0 1 1 1 0 BclA C-terminal domain FlaC_arch PF05377.11 CBY38530.1 - 0.026 14.9 44.8 2.1 8.8 0.2 10.9 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) Tropomyosin_1 PF12718.7 CBY38530.1 - 0.026 14.7 48.5 0.035 14.3 1.4 7.2 2 2 2 5 5 5 0 Tropomyosin like Prominin PF05478.11 CBY38530.1 - 0.08 10.9 40.2 0.12 10.3 2.8 4.5 2 1 3 5 5 5 0 Prominin Filament PF00038.21 CBY38530.1 - 0.2 11.2 47.9 2.6 7.6 1.2 6.4 2 2 2 4 4 4 0 Intermediate filament protein Laminin_II PF06009.12 CBY38530.1 - 0.6 10.1 44.9 2.7 8.0 4.6 7.6 4 3 5 9 9 9 0 Laminin Domain II eIF-5a PF01287.20 CBY38530.1 - 0.8 9.9 6.4 0.85 9.8 0.0 3.7 5 0 0 5 5 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold bZIP_1 PF00170.21 CBY38530.1 - 0.94 9.6 17.5 1.2 9.2 0.2 6.1 7 1 0 7 7 7 0 bZIP transcription factor Fib_alpha PF08702.10 CBY38530.1 - 1.9 8.6 41.8 1.2 9.4 0.5 7.0 3 3 2 7 7 7 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CBY38530.1 - 2.5 7.6 34.9 2.6 7.6 0.5 4.3 1 1 3 4 4 4 0 Exonuclease VII, large subunit DUF2536 PF10750.9 CBY38530.1 - 3 7.8 5.4 0.74 9.8 0.3 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF2536) Prefoldin PF02996.17 CBY38530.1 - 3.9 7.4 30.3 2.9 7.8 0.3 7.6 7 1 0 7 7 7 0 Prefoldin subunit DUF4472 PF14739.6 CBY38530.1 - 5.1 7.9 32.8 1.4 9.7 2.4 6.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4472) CorA PF01544.18 CBY38530.1 - 5.4 6.3 21.3 2.1 7.6 7.4 4.1 3 2 1 4 4 4 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 CBY38530.1 - 6.4 6.8 43.0 1.9 8.5 8.2 5.5 3 3 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 CBY38530.1 - 9 6.4 50.2 1.3 9.1 1.0 6.8 4 3 2 6 6 6 0 TPR/MLP1/MLP2-like protein LRR_8 PF13855.6 CBY38531.1 - 1.1e-31 108.4 18.4 2e-10 40.3 0.1 4.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 CBY38531.1 - 1e-13 51.4 0.0 1.5e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY38531.1 - 3.2e-13 49.6 15.0 0.00099 19.5 1.5 5.9 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY38531.1 - 0.0015 18.8 5.5 55 4.9 0.0 6.6 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 CBY38531.1 - 0.0049 16.4 4.2 0.13 11.8 0.8 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBY38531.1 - 0.31 11.2 13.1 23 5.3 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Got1 PF04178.12 CBY38532.1 - 4.5e-29 101.1 6.7 5.1e-29 101.0 6.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family TFIIA PF03153.13 CBY38533.1 - 1.8e-47 163.3 28.0 3.9e-47 162.2 28.0 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit V-ATPase_C PF03223.15 CBY38534.1 - 1.3e-95 321.0 0.1 1.6e-95 320.7 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CytochromB561_N PF09786.9 CBY38535.1 - 1.4e-34 120.1 3.2 3.6e-34 118.7 3.2 1.6 1 1 0 1 1 1 1 Cytochrome B561, N terminal V-ATPase_C PF03223.15 CBY38535.1 - 2.1e-24 86.6 0.0 5.2e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 V-ATPase subunit C CytochromB561_N PF09786.9 CBY38536.1 - 1.3e-34 120.2 1.7 2.9e-34 119.0 1.7 1.5 1 1 0 1 1 1 1 Cytochrome B561, N terminal DUF1542 PF07564.11 CBY38537.1 - 0.0013 18.8 2.5 0.0024 17.9 2.5 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1542) ABC_trans_N PF14510.6 CBY38537.1 - 2 9.1 4.0 8.3 7.1 0.1 2.7 2 1 1 3 3 3 0 ABC-transporter N-terminal hGDE_central PF14702.6 CBY38539.1 - 0.063 12.9 0.9 0.098 12.3 0.1 1.7 2 0 0 2 2 2 0 Central domain of human glycogen debranching enzyme Laminin_B PF00052.18 CBY38539.1 - 0.096 12.6 1.6 0.21 11.5 1.1 1.8 1 1 0 1 1 1 0 Laminin B (Domain IV) Raffinose_syn PF05691.12 CBY38540.1 - 0.0007 17.5 0.0 0.0012 16.8 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 SPOC PF07744.13 CBY38541.1 - 7.3e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 SPOC domain CxC7 PF18866.1 CBY38541.1 - 0.087 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF3006 PF11213.8 CBY38542.1 - 0.036 14.3 0.1 16 5.8 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3006) Histone PF00125.24 CBY38542.1 - 0.36 11.2 4.8 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 DUF3006 PF11213.8 CBY38543.1 - 0.055 13.7 1.5 19 5.6 0.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3006) Y_phosphatase PF00102.27 CBY38545.1 - 1.4e-60 204.8 1.2 4.3e-32 111.6 0.1 2.1 1 1 1 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY38545.1 - 0.00096 19.2 0.1 0.0053 16.8 0.0 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 CBY38545.1 - 0.0023 17.7 0.3 0.0087 15.9 0.3 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY38545.1 - 0.012 15.8 0.1 0.06 13.5 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CBY38545.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Rhodanese PF00581.20 CBY38545.1 - 0.062 13.8 0.0 5.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Rhodanese-like domain ANAPC4_WD40 PF12894.7 CBY38546.1 - 4.1e-08 33.4 1.1 0.0028 17.9 0.1 4.8 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY38546.1 - 0.0085 16.9 14.3 0.14 13.0 0.2 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY38546.1 - 0.078 12.0 0.2 10 5.1 0.0 2.4 1 1 1 2 2 2 0 Coatomer WD associated region DUF5422 PF17459.2 CBY38546.1 - 0.21 11.8 0.1 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5422) Sulfotransfer_1 PF00685.27 CBY38547.1 - 4.2e-05 23.2 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain WSC PF01822.19 CBY38547.1 - 0.028 14.6 1.3 0.046 13.9 1.3 1.3 1 0 0 1 1 1 0 WSC domain DUF1065 PF06358.11 CBY38549.1 - 0.39 10.7 1.2 7 6.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1065) Telomere_reg-2 PF10193.9 CBY38550.1 - 3.7e-08 33.8 2.0 2.7e-07 31.0 0.4 3.0 3 0 0 3 3 3 1 Telomere length regulation protein SecA_DEAD PF07517.14 CBY38550.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain PfkB PF00294.24 CBY38551.1 - 1.9e-13 50.4 0.1 1.9e-12 47.2 0.1 1.9 1 1 1 2 2 2 2 pfkB family carbohydrate kinase EF-hand_1 PF00036.32 CBY38552.1 - 1e-07 30.9 0.4 4.1e-06 26.0 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY38552.1 - 8.4e-07 28.4 0.1 0.00024 20.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBY38552.1 - 2.7e-06 26.6 0.7 0.00021 20.6 0.3 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY38552.1 - 6.9e-06 26.4 0.0 1.9e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY38552.1 - 4.5e-05 23.2 0.2 0.00018 21.3 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair UBA_2 PF08587.11 CBY38552.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) p25-alpha PF05517.12 CBY38552.1 - 0.16 12.1 0.6 0.65 10.2 0.2 2.1 2 0 0 2 2 2 0 p25-alpha VWA_3 PF13768.6 CBY38553.1 - 1.8e-13 50.7 0.0 9.1e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 CBY38553.1 - 1.3e-08 35.3 0.2 0.00085 19.6 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VIT PF08487.10 CBY38553.1 - 1.8e-05 24.9 1.2 4.6e-05 23.6 1.2 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 CBY38553.1 - 8.7e-05 23.1 0.0 0.49 11.1 0.0 2.6 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY38553.1 - 0.0016 17.8 0.2 1 8.7 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein WD40 PF00400.32 CBY38554.1 - 7.5e-19 67.7 14.9 6.4e-05 23.6 0.0 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY38554.1 - 6.6e-15 55.2 0.4 0.0016 18.7 0.0 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY38554.1 - 3.2e-07 30.0 0.1 0.14 11.5 0.0 3.5 3 0 0 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 CBY38554.1 - 0.037 13.0 0.1 0.33 9.9 0.1 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Prefoldin_2 PF01920.20 CBY38555.1 - 2.2e-06 27.6 2.3 3.1e-06 27.1 2.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit PP1c_bdg PF10488.9 CBY38555.1 - 0.0045 16.5 0.3 0.0049 16.4 0.3 1.2 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region RmuC PF02646.16 CBY38555.1 - 0.019 14.1 5.0 0.15 11.1 0.8 2.0 2 0 0 2 2 2 0 RmuC family Prefoldin PF02996.17 CBY38555.1 - 0.032 14.1 8.1 0.19 11.6 8.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBY38555.1 - 0.23 11.5 9.8 0.79 9.8 2.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.25 CBY38555.1 - 0.27 10.9 6.6 3.8 7.1 0.8 2.1 2 0 0 2 2 2 0 Syntaxin DUF1664 PF07889.12 CBY38555.1 - 0.31 11.1 3.8 2.7 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CBY38555.1 - 0.39 11.2 5.9 7.6 7.0 1.5 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.10 CBY38555.1 - 0.42 10.9 3.3 7.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF2443 PF10398.9 CBY38555.1 - 0.52 10.4 3.5 0.81 9.8 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DivIC PF04977.15 CBY38555.1 - 1.1 9.0 6.3 4.2 7.2 3.7 2.1 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 CBY38555.1 - 1.3 9.5 8.4 0.99 9.8 1.2 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Glyco_hydro_15 PF00723.21 CBY38556.1 - 2.7e-96 323.1 0.0 3.6e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_transf_90 PF05686.12 CBY38559.1 - 5.8e-24 84.7 0.2 6.9e-24 84.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 DUF1640 PF07798.11 CBY38560.1 - 0.0096 16.0 1.3 0.08 13.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) SIT PF15330.6 CBY38560.1 - 0.032 14.7 0.1 0.041 14.3 0.1 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Claudin_3 PF06653.11 CBY38560.1 - 0.033 14.1 0.2 0.039 13.9 0.2 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like MIP PF00230.20 CBY38561.1 - 4.3e-36 124.8 2.4 5.6e-36 124.4 2.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_transf_10 PF00852.19 CBY38562.1 - 3.6e-48 163.6 0.0 8.5e-48 162.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term RIO1 PF01163.22 CBY38563.1 - 0.0089 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY38563.1 - 0.13 11.6 0.1 2 7.8 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBY38564.1 - 0.0082 15.5 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 CBY38564.1 - 0.042 13.4 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SepSecS PF05889.13 CBY38565.1 - 2.8e-108 362.1 0.0 3.3e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CBY38565.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Phospholip_A2_1 PF00068.19 CBY38566.1 - 1.5e-16 60.8 6.1 2.2e-16 60.3 6.1 1.1 1 0 0 1 1 1 1 Phospholipase A2 MMACHC PF16690.5 CBY38567.1 - 4.7e-28 98.3 0.0 5.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family CKS PF01111.19 CBY38567.1 - 0.08 13.2 0.2 0.2 12.0 0.1 1.8 1 1 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit 7tm_1 PF00001.21 CBY38568.1 - 7e-10 38.7 10.7 7e-10 38.7 10.7 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4383 PF14325.6 CBY38568.1 - 0.078 13.3 2.7 0.35 11.1 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) TMEM208_SND2 PF05620.11 CBY38568.1 - 1.4 8.7 7.3 19 5.0 0.0 3.0 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF1633 PF07794.11 CBY38569.1 - 2.7 6.1 4.2 2.9 6.0 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) API5 PF05918.11 CBY38569.1 - 2.8 6.6 7.9 3.6 6.3 7.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Homeodomain PF00046.29 CBY38570.1 - 1.8e-21 75.7 3.3 3.6e-21 74.8 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY38570.1 - 0.0091 15.9 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF4542 PF15075.6 CBY38570.1 - 0.096 13.1 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) OTOS PF15182.6 CBY38570.1 - 0.16 11.9 0.4 0.43 10.5 0.2 1.7 2 0 0 2 2 2 0 Otospiralin Auxin_canalis PF05703.11 CBY38570.1 - 0.46 10.4 4.1 0.31 10.9 0.8 1.8 1 1 1 2 2 2 0 Auxin canalisation TSP_1 PF00090.19 CBY38571.1 - 5.2e-05 23.4 7.2 0.00026 21.1 7.2 2.3 1 0 0 1 1 1 1 Thrombospondin type 1 domain PAN_4 PF14295.6 CBY38571.1 - 0.0013 18.6 0.4 0.0013 18.6 0.4 3.7 4 1 0 4 4 4 1 PAN domain PAN_3 PF08277.12 CBY38571.1 - 0.03 14.1 0.7 0.03 14.1 0.7 3.1 2 1 1 3 3 3 0 PAN-like domain Lactamase_B PF00753.27 CBY38574.1 - 6.7e-14 52.4 3.9 6e-12 46.0 3.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY38574.1 - 0.0082 15.7 0.9 0.014 14.9 0.9 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUB PF00431.20 CBY38575.1 - 3e-08 34.0 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain Presenilin PF01080.17 CBY38575.1 - 0.32 9.7 1.0 0.45 9.2 1.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 CBY38575.1 - 0.83 9.9 7.2 1.4 9.1 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Spt20 PF12090.8 CBY38575.1 - 0.89 9.1 10.3 1.4 8.5 10.3 1.4 1 0 0 1 1 1 0 Spt20 family ADH_N PF08240.12 CBY38576.1 - 2.9e-28 97.9 4.6 6.1e-28 96.9 4.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CBY38576.1 - 5.9e-09 35.7 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 CBY38576.1 - 2.2e-07 30.9 0.0 4.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase RELT PF12606.8 CBY38576.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 tRNA-synt_1c PF00749.21 CBY38578.1 - 7.6e-107 356.8 0.0 1.1e-106 356.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBY38578.1 - 3e-35 121.7 0.2 7.2e-35 120.4 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 CBY38578.1 - 8.6e-34 116.9 0.9 8.6e-34 116.9 0.9 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 CBY38578.1 - 1e-22 80.8 4.0 3.1e-22 79.3 4.0 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 LAGLIDADG_1 PF00961.19 CBY38578.1 - 0.021 15.8 0.4 0.071 14.1 0.4 1.9 1 0 0 1 1 1 0 LAGLIDADG endonuclease PAC3 PF10178.9 CBY38579.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 LRR_8 PF13855.6 CBY38580.1 - 6.5e-14 51.4 32.2 9.3e-07 28.5 7.9 4.9 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 CBY38580.1 - 5.4e-13 48.9 39.0 1.3e-06 28.7 3.3 6.9 2 2 4 6 6 6 3 Leucine Rich repeats (2 copies) zf-C3HC4_3 PF13920.6 CBY38580.1 - 6.6e-11 41.9 18.0 1.3e-10 41.0 18.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_1 PF00536.30 CBY38580.1 - 1.6e-05 25.2 0.1 5e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY38580.1 - 0.00096 19.2 0.1 0.0041 17.2 0.1 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 CBY38580.1 - 0.041 13.8 19.5 0.088 12.7 19.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY38580.1 - 0.12 12.7 20.6 0.3 11.5 20.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CBY38580.1 - 0.76 9.8 18.2 1.7 8.7 18.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain LRR_6 PF13516.6 CBY38581.1 - 2e-15 55.4 14.1 0.00048 20.0 0.4 8.8 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 CBY38581.1 - 6.5e-07 29.6 7.7 1.3 9.6 0.0 5.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY38581.1 - 0.022 14.5 11.1 0.39 10.5 0.2 5.5 4 2 0 5 5 5 0 Leucine rich repeat nos_propeller PF18764.1 CBY38581.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat LRR_1 PF00560.33 CBY38581.1 - 0.077 13.6 9.8 11 7.0 0.5 6.0 6 2 0 6 6 6 0 Leucine Rich Repeat COS PF18568.1 CBY38581.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Fibrinogen_BP PF08017.11 CBY38582.1 - 0.32 9.4 0.3 0.35 9.3 0.3 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein adh_short_C2 PF13561.6 CBY38583.1 - 6.4e-58 196.1 0.9 7.5e-58 195.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBY38583.1 - 5.9e-45 153.1 0.5 8.3e-45 152.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CBY38583.1 - 1.6e-05 24.5 0.1 5.5e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CBY38583.1 - 0.034 14.2 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Corona_NS2A PF05213.12 CBY38583.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein 3HCDH_N PF02737.18 CBY38583.1 - 0.14 12.0 0.5 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hist_deacetyl PF00850.19 CBY38585.1 - 4.3e-85 285.9 0.0 5.2e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Rhodanese PF00581.20 CBY38586.1 - 1.7e-09 38.1 0.0 3.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain MFS_5 PF05631.14 CBY38588.1 - 2.1e-50 171.7 6.3 2.6e-50 171.3 6.3 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY38588.1 - 3.9e-07 29.3 15.8 4.6e-05 22.5 3.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2512 PF10710.9 CBY38588.1 - 0.1 12.2 0.2 0.1 12.2 0.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2512) WD40 PF00400.32 CBY38589.1 - 0.00053 20.7 1.8 15 6.7 1.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-C3HC4 PF00097.25 CBY38590.1 - 4.8e-08 32.7 7.3 4.8e-08 32.7 7.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY38590.1 - 8.9e-08 31.8 7.6 8.9e-08 31.8 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY38590.1 - 7e-07 29.3 8.6 7e-07 29.3 8.6 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBY38590.1 - 1e-06 28.7 3.9 1e-06 28.7 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY38590.1 - 2.4e-05 24.6 10.5 2.4e-05 24.6 10.5 3.0 2 1 1 3 3 3 1 Ring finger domain zf-ANAPC11 PF12861.7 CBY38590.1 - 7.4e-05 22.7 3.0 7.4e-05 22.7 3.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBY38590.1 - 0.00012 21.9 8.3 0.00012 21.9 8.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY38590.1 - 0.00055 19.8 9.4 0.00055 19.8 9.4 2.8 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 CBY38590.1 - 0.0037 17.1 3.3 0.0037 17.1 3.3 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBY38590.1 - 0.0094 15.7 10.6 0.0094 15.7 10.6 3.2 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 CBY38590.1 - 0.019 15.2 4.0 0.019 15.2 4.0 2.7 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_4 PF13717.6 CBY38590.1 - 0.021 14.8 0.5 0.021 14.8 0.5 3.6 5 0 0 5 5 5 0 zinc-ribbon domain Prok-RING_4 PF14447.6 CBY38590.1 - 0.024 14.5 7.3 0.024 14.5 7.3 3.4 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 Vg_Tdu PF07545.14 CBY38591.1 - 0.046 13.5 1.4 6.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family HCV_env PF01539.17 CBY38591.1 - 0.085 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 UNC-50 PF05216.13 CBY38592.1 - 2e-42 145.3 3.6 2.4e-42 145.0 3.6 1.1 1 0 0 1 1 1 1 UNC-50 family Tmemb_55A PF09788.9 CBY38592.1 - 0.032 13.3 1.3 0.044 12.9 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A FA_desaturase PF00487.24 CBY38592.1 - 0.041 13.7 0.6 0.052 13.4 0.6 1.1 1 0 0 1 1 1 0 Fatty acid desaturase EGF_CA PF07645.15 CBY38593.1 - 3.2e-24 84.9 124.0 4e-08 33.3 7.2 10.2 9 1 2 11 11 11 7 Calcium-binding EGF domain cEGF PF12662.7 CBY38593.1 - 1.7e-18 66.2 78.7 1.7e-05 24.6 2.2 11.9 11 2 0 11 11 11 7 Complement Clr-like EGF-like TB PF00683.17 CBY38593.1 - 2.1e-18 65.8 38.3 1.1e-09 37.9 14.3 5.1 5 0 0 5 5 5 3 TB domain EGF PF00008.27 CBY38593.1 - 3.7e-15 55.9 107.1 0.00017 21.8 3.9 10.2 9 1 1 10 10 10 6 EGF-like domain hEGF PF12661.7 CBY38593.1 - 1e-09 38.7 116.6 0.0019 18.8 2.7 12.3 13 0 0 13 13 13 6 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY38593.1 - 6.6e-06 26.3 126.6 0.0058 16.9 8.0 10.4 9 3 1 10 10 10 7 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY38593.1 - 0.0029 17.9 11.2 0.0029 17.9 11.2 8.0 7 2 1 8 8 8 4 Pvs28 EGF domain EGF_3 PF12947.7 CBY38593.1 - 2 8.6 110.9 0.037 14.2 6.9 11.3 9 3 1 10 10 10 0 EGF domain Pkinase_Tyr PF07714.17 CBY38594.1 - 4.1e-66 222.9 0.0 5e-40 137.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY38594.1 - 8.3e-28 97.5 0.0 8.5e-21 74.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 CBY38594.1 - 0.044 13.7 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY38594.1 - 0.045 12.7 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain ubiquitin PF00240.23 CBY38595.1 - 0.0052 16.5 0.0 0.0054 16.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PI3K_rbd PF00794.18 CBY38595.1 - 0.055 13.6 0.0 0.055 13.6 0.0 1.0 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DEAD PF00270.29 CBY38596.1 - 6.8e-43 146.5 0.3 1.1e-42 145.8 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY38596.1 - 9.8e-33 112.8 0.0 4.9e-31 107.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY38596.1 - 4e-06 26.9 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBY38596.1 - 8.2e-05 23.0 0.3 0.0009 19.6 0.4 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBY38596.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 CBY38596.1 - 0.00019 20.3 0.0 0.04 12.7 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 CBY38596.1 - 0.048 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 CBY38596.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 CBY38596.1 - 0.12 12.4 0.3 0.46 10.4 0.1 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain DUF1833 PF08875.11 CBY38596.1 - 0.12 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) PhoH PF02562.16 CBY38596.1 - 0.15 11.5 1.5 0.33 10.4 0.3 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CBY38596.1 - 0.15 12.3 1.1 1.3 9.3 1.1 2.3 1 1 0 1 1 1 0 AAA domain Fibrillarin PF01269.17 CBY38597.1 - 1.9e-106 354.3 0.0 2.3e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBY38597.1 - 6.9e-05 22.6 0.1 9.9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CBY38597.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CBY38597.1 - 0.055 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CBY38597.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FAA_hydrolase PF01557.18 CBY38598.1 - 1e-54 185.5 0.0 1.4e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CBY38598.1 - 4.5e-29 100.8 0.0 8.3e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Glycophorin_A PF01102.18 CBY38599.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Pkinase PF00069.25 CBY38601.1 - 2.1e-31 109.3 0.0 4.4e-31 108.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CBY38601.1 - 1.3e-08 34.5 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CBY38601.1 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY38601.1 - 0.00014 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY38601.1 - 0.0018 17.9 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY38601.1 - 0.0037 16.6 0.0 0.0093 15.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBY38601.1 - 0.0046 15.8 0.1 0.0067 15.2 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Filament PF00038.21 CBY38603.1 - 0.00086 19.0 1.0 0.0013 18.4 1.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein zf-MYND PF01753.18 CBY38603.1 - 0.0019 18.2 15.1 0.0036 17.4 15.1 1.5 1 0 0 1 1 1 1 MYND finger RAG1_imp_bd PF12560.8 CBY38603.1 - 0.026 14.1 0.5 0.026 14.1 0.5 2.2 2 0 0 2 2 2 0 RAG1 importin binding zf-C3HC4_2 PF13923.6 CBY38605.1 - 1.4e-10 40.9 11.0 1.4e-10 40.9 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY38605.1 - 3e-08 33.4 9.8 3e-08 33.4 9.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY38605.1 - 6.2e-08 32.4 7.9 1.2e-07 31.5 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY38605.1 - 8.8e-08 32.1 8.9 2.3e-07 30.7 8.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY38605.1 - 9.2e-08 31.9 10.6 2.2e-07 30.7 10.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY38605.1 - 5.5e-07 29.8 10.7 5.5e-07 29.8 10.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 CBY38605.1 - 5.7e-07 29.6 5.7 1.3e-06 28.4 5.7 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CBY38605.1 - 1.4e-05 25.2 9.3 3.5e-05 23.9 9.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CBY38605.1 - 3.1e-05 23.8 3.1 4.9e-05 23.1 3.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY38605.1 - 8.6e-05 22.3 10.0 0.00019 21.2 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UNC-79 PF14776.6 CBY38605.1 - 0.012 14.4 4.0 0.016 14.0 4.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 zf-P11 PF03854.14 CBY38605.1 - 0.14 11.9 5.8 0.3 10.8 5.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 CBY38605.1 - 0.17 11.7 3.9 0.42 10.4 3.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CBY38605.1 - 2.5 8.2 7.0 12 6.0 7.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 CBY38605.1 - 6.8 7.1 14.4 0.3 11.4 7.6 2.3 2 1 0 2 2 1 0 RING-H2 zinc finger domain GP41 PF00517.17 CBY38606.1 - 0.064 13.2 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein BRE1 PF08647.11 CBY38607.1 - 0.0072 16.4 10.5 0.0072 16.4 10.5 8.0 4 2 4 8 8 8 2 BRE1 E3 ubiquitin ligase ATP-synt_C PF00137.21 CBY38608.1 - 8.6e-33 112.5 35.4 2.9e-21 75.6 13.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 CBY38608.1 - 0.3 10.7 1.1 0.51 9.9 1.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family NADH5_C PF06455.11 CBY38608.1 - 3.8 7.1 12.2 0.055 13.1 5.2 1.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus LSM PF01423.22 CBY38609.1 - 1.8e-23 82.0 0.1 1.9e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY38609.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 CBY38609.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein VERL PF11386.8 CBY38609.1 - 0.11 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin RUN PF02759.19 CBY38610.1 - 1.3e-11 44.6 0.2 4.6e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 RUN domain VIT1 PF01988.19 CBY38610.1 - 0.01 15.7 2.0 0.39 10.5 1.1 2.6 1 1 0 1 1 1 0 VIT family Dna2 PF08696.11 CBY38610.1 - 0.017 14.9 4.7 0.31 10.8 0.9 3.1 2 1 1 3 3 3 0 DNA replication factor Dna2 Tropomyosin_1 PF12718.7 CBY38610.1 - 2.7 8.1 17.5 0.032 14.4 2.7 3.0 2 1 0 2 2 2 0 Tropomyosin like Pou PF00157.17 CBY38611.1 - 2.2e-23 82.0 0.0 5.6e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY38611.1 - 3.1e-07 30.1 0.3 7.5e-07 28.9 0.3 1.7 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CBY38611.1 - 0.0041 17.4 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LcrR PF09621.10 CBY38611.1 - 0.027 13.9 0.4 0.074 12.5 0.1 1.9 2 1 0 2 2 2 0 Type III secretion system regulator (LcrR) HTH_ABP1_N PF18107.1 CBY38611.1 - 0.048 13.4 2.5 9.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain Mito_carr PF00153.27 CBY38612.1 - 1.2e-46 156.5 1.4 1.5e-18 66.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 CBY38613.1 - 1e-67 228.9 0.0 1.2e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Complex1_49kDa PF00346.19 CBY38614.1 - 1.6e-118 394.8 0.0 2e-118 394.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CBY38614.1 - 0.051 12.5 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Pro_isomerase PF00160.21 CBY38615.1 - 6.4e-52 176.0 0.1 7.4e-52 175.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EGF_CA PF07645.15 CBY38616.1 - 1.5e-31 108.3 60.4 2.4e-11 43.6 9.8 4.7 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.7 CBY38616.1 - 3.7e-06 27.0 57.3 0.00077 19.6 9.5 4.8 4 0 0 4 4 4 3 EGF domain cEGF PF12662.7 CBY38616.1 - 0.00015 21.7 27.9 0.00076 19.4 1.1 5.3 5 0 0 5 5 5 3 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY38616.1 - 0.029 14.7 49.8 0.26 11.6 7.6 5.1 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY38616.1 - 2.4 8.6 37.5 0.038 14.3 5.1 4.5 3 0 0 3 3 3 0 EGF-like domain DUF2207 PF09972.9 CBY38617.1 - 0.11 11.2 0.2 0.4 9.4 0.1 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CH PF00307.31 CBY38618.1 - 8.8e-18 64.5 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CBY38618.1 - 1.6e-09 37.2 7.1 2.6e-09 36.6 3.6 2.6 2 0 0 2 2 2 1 Calponin family repeat SAP PF02037.27 CBY38619.1 - 0.18 11.6 1.0 0.39 10.5 0.2 2.0 2 0 0 2 2 2 0 SAP domain Neur_chan_LBD PF02931.23 CBY38621.1 - 1.1e-45 155.8 4.2 1.3e-45 155.5 4.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY38622.1 - 2e-23 83.7 0.0 2.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1152 PF06626.12 CBY38622.1 - 0.087 12.0 0.4 0.12 11.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) CTP_synth_N PF06418.14 CBY38623.1 - 3.9e-114 380.4 0.5 4.8e-114 380.1 0.5 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus CbiA PF01656.23 CBY38623.1 - 0.029 14.4 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain EGF_2 PF07974.13 CBY38623.1 - 1.4 9.3 27.9 1.9 8.9 18.2 2.4 2 0 0 2 2 2 0 EGF-like domain VESA1_N PF12785.7 CBY38623.1 - 3.4 6.5 9.6 4.8 6.0 9.6 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Rad60-SLD PF11976.8 CBY38624.1 - 5e-22 77.5 0.2 6e-22 77.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY38624.1 - 4.7e-10 39.1 0.1 5.9e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY38625.1 - 0.0032 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Utp12 PF04003.12 CBY38626.1 - 6.2e-08 32.9 0.0 7.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Dip2/Utp12 Family Kelch_6 PF13964.6 CBY38627.1 - 9.6e-07 28.9 0.3 0.072 13.4 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CBY38627.1 - 6.1e-05 23.0 1.2 0.97 9.5 0.0 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY38627.1 - 0.00014 21.7 3.4 0.0011 18.9 0.0 4.0 5 1 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 CBY38627.1 - 0.00066 19.6 0.0 0.048 13.7 0.0 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CBY38627.1 - 0.0022 18.2 0.3 0.36 11.2 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY38627.1 - 0.016 14.7 0.1 2 8.0 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.25 CBY38630.1 - 5.5e-09 35.8 0.0 9.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38630.1 - 1.1e-06 28.1 0.1 2.9e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 CBY38632.1 - 1.1e-21 77.3 0.1 1.5e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY38632.1 - 3.2e-12 46.3 0.0 4.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY38632.1 - 4.3e-12 45.9 0.0 5.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HNOBA PF07701.14 CBY38632.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated WD40 PF00400.32 CBY38633.1 - 6e-10 39.6 1.1 0.00016 22.4 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Ank_2 PF12796.7 CBY38634.1 - 2.7e-102 335.5 20.1 2.7e-14 53.5 0.7 10.5 3 3 9 13 13 13 13 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY38634.1 - 7e-101 329.0 17.9 9e-10 38.6 0.0 15.9 6 5 9 15 15 15 15 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY38634.1 - 1.5e-89 293.3 31.5 6e-11 42.6 0.0 14.0 6 5 11 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY38634.1 - 1.6e-84 267.6 13.0 6.4e-06 26.1 0.1 18.9 19 0 0 19 19 19 14 Ankyrin repeat Ank PF00023.30 CBY38634.1 - 2.3e-81 264.9 19.4 2.4e-05 24.6 0.1 18.1 18 0 0 18 18 18 16 Ankyrin repeat PARP PF00644.20 CBY38634.1 - 2.2e-25 89.4 1.6 9.3e-23 80.8 1.6 2.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SAM_1 PF00536.30 CBY38634.1 - 2.9e-10 40.4 0.2 7.4e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY38634.1 - 1.6e-09 37.7 0.1 4.6e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4878 PF12870.7 CBY38634.1 - 0.12 12.7 0.0 3 8.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4878) DDOST_48kD PF03345.14 CBY38635.1 - 5.1e-114 381.3 0.0 6.7e-114 380.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2194 PF09960.9 CBY38635.1 - 0.00063 18.2 0.0 0.00085 17.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) DUF4149 PF13664.6 CBY38635.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF4485 PF14846.6 CBY38636.1 - 0.027 14.5 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF3116 PF11313.8 CBY38636.1 - 0.083 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) DUF4901 PF16244.5 CBY38637.1 - 0.016 14.6 1.6 0.028 13.8 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4901) Ribosomal_S30AE PF02482.19 CBY38637.1 - 0.036 14.9 2.0 4.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein WEMBL PF05701.11 CBY38637.1 - 0.038 12.7 19.3 0.059 12.1 19.3 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NUMOD3 PF07460.11 CBY38637.1 - 0.15 12.3 2.4 4.1 7.7 0.1 3.0 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Atg14 PF10186.9 CBY38637.1 - 7.9 5.5 22.8 0.6 9.1 16.3 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF753 PF05444.12 CBY38638.1 - 0.94 9.5 9.6 1.8 8.5 1.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF753) SART-1 PF03343.13 CBY38640.1 - 2.4e-32 112.3 4.6 3e-32 112.0 4.6 1.1 1 0 0 1 1 1 1 SART-1 family MFS_1 PF07690.16 CBY38641.1 - 4.5e-38 131.1 19.2 3.7e-37 128.1 18.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY38641.1 - 1.5e-09 37.3 9.3 1.5e-09 37.3 9.3 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CBY38641.1 - 3.2e-08 32.5 3.1 5.3e-08 31.7 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CBY38641.1 - 1.8e-07 29.9 12.6 0.0072 14.7 0.9 4.1 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 CBY38641.1 - 0.049 12.5 18.7 0.081 11.8 0.9 3.4 2 2 1 3 3 3 0 MFS_1 like family Rick_17kDa_Anti PF05433.15 CBY38641.1 - 2 8.3 5.8 2.4 8.1 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF2631 PF10939.8 CBY38641.1 - 4.5 7.2 6.7 0.4 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) LptC PF06835.13 CBY38643.1 - 0.037 13.6 1.6 0.049 13.2 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related DUF4522 PF15022.6 CBY38643.1 - 1.8 8.8 4.6 1.7 8.9 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4522) Glyco_hydro_18 PF00704.28 CBY38644.1 - 3.8e-85 286.4 0.4 6.4e-85 285.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LPMO_10 PF03067.15 CBY38644.1 - 3.5e-30 106.1 1.1 6.5e-30 105.2 0.2 2.0 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY38644.1 - 2.4e-24 85.3 29.8 8.5e-13 48.3 6.5 4.2 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain DAG_kinase_N PF14513.6 CBY38644.1 - 0.11 12.7 0.2 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RAP1 PF07218.11 CBY38644.1 - 0.61 8.3 7.2 0.93 7.7 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PRR18 PF15671.5 CBY38644.1 - 1.6 8.6 10.6 0.035 14.0 3.5 1.8 2 0 0 2 2 2 0 Proline-rich protein family 18 EMP24_GP25L PF01105.24 CBY38646.1 - 7.5e-50 169.4 0.5 8.6e-50 169.2 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TRPM_tetra PF16519.5 CBY38646.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Zn-C2H2_12 PF18112.1 CBY38647.1 - 4.7e-12 46.1 5.2 1.3e-11 44.7 5.2 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CBY38647.1 - 0.15 12.4 0.8 0.31 11.3 0.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding EVI2A PF05399.11 CBY38647.1 - 4.1 6.9 8.8 1.1 8.7 5.5 1.7 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) fn3 PF00041.21 CBY38648.1 - 0.005 17.2 0.0 0.0069 16.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain DREV PF05219.12 CBY38651.1 - 2.7e-14 52.9 0.0 3.1e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_23 PF13489.6 CBY38651.1 - 3.9e-09 36.5 0.0 1.2e-07 31.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY38651.1 - 4.7e-07 30.5 0.1 1e-06 29.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY38651.1 - 2.1e-05 24.4 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CBY38651.1 - 3.5e-05 23.5 0.2 9.7e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 CBY38651.1 - 4.8e-05 24.0 0.0 8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY38651.1 - 0.00024 21.7 0.0 0.0004 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY38651.1 - 0.0077 15.8 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CBY38651.1 - 0.009 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RNase_T PF00929.24 CBY38652.1 - 7.3e-23 81.9 0.0 1.6e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 Exonuclease DNA_methylase PF00145.17 CBY38652.1 - 0.048 13.0 1.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase WH1 PF00568.23 CBY38652.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 WH1 domain Pkinase PF00069.25 CBY38653.1 - 5e-59 199.8 0.0 8e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38653.1 - 4.3e-31 108.1 0.0 8.1e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY38653.1 - 1.6e-08 34.2 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY38653.1 - 0.0076 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0565 PF10561.9 CBY38653.1 - 1.8 7.7 7.5 3.3 6.8 7.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 LMBR1 PF04791.16 CBY38653.1 - 3.5 6.4 7.3 6.1 5.6 7.3 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein PHD PF00628.29 CBY38655.1 - 0.0026 17.6 6.4 0.0064 16.4 6.4 1.7 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 CBY38655.1 - 0.034 14.3 4.0 0.11 12.6 4.0 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 CBY38655.1 - 0.044 13.7 6.6 0.076 12.9 6.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.32 CBY38656.1 - 3e-22 78.5 10.5 0.0073 17.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CBY38656.1 - 3.8e-10 39.4 11.0 3.8e-10 39.4 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY38656.1 - 2.4e-08 33.7 9.8 8.5e-08 32.0 9.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY38656.1 - 1.3e-07 31.3 7.9 3.5e-07 30.0 7.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 CBY38656.1 - 1.8e-07 31.3 2.3 1.5 9.1 1.3 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 CBY38656.1 - 2.3e-07 30.7 8.9 6.5e-07 29.3 8.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger WD40_like PF17005.5 CBY38656.1 - 5.4e-07 29.2 0.8 6.5e-05 22.4 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain zf-RING_5 PF14634.6 CBY38656.1 - 6.2e-07 29.3 10.6 6.2e-07 29.3 10.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 CBY38656.1 - 1.4e-06 28.3 5.9 4.8e-06 26.6 5.9 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CBY38656.1 - 1.5e-06 28.4 10.7 1.5e-06 28.4 10.7 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBY38656.1 - 3.1e-05 24.0 9.3 9.7e-05 22.4 9.3 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CBY38656.1 - 8.1e-05 22.4 3.2 0.00016 21.5 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY38656.1 - 0.00024 20.9 10.0 0.00056 19.7 10.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UNC-79 PF14776.6 CBY38656.1 - 0.0057 15.5 3.2 0.0093 14.8 3.2 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DUF5026 PF16429.5 CBY38656.1 - 0.048 13.8 0.1 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) zf-P11 PF03854.14 CBY38656.1 - 0.29 10.8 5.8 0.85 9.3 5.8 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 CBY38656.1 - 1.8 8.4 6.3 6.3 6.7 6.3 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CBY38656.1 - 5.1 7.5 15.4 0.69 10.3 7.4 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain Carboxyl_trans PF01039.22 CBY38657.1 - 3.4e-150 501.0 0.0 4.1e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBY38657.1 - 3e-05 23.6 0.0 0.046 13.2 0.0 2.7 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) MDD_C PF18376.1 CBY38658.1 - 1.6e-56 191.0 0.0 2.8e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBY38658.1 - 7.3e-06 26.1 1.5 2.7e-05 24.3 1.5 1.9 3 0 0 3 3 3 1 GHMP kinases N terminal domain Glyco_hydro_72 PF03198.14 CBY38658.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Elongin_A PF06881.11 CBY38659.1 - 0.093 13.3 3.8 0.19 12.3 3.8 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A EGF_CA PF07645.15 CBY38660.1 - 5.2e-05 23.4 9.4 5.2e-05 23.4 9.4 2.3 2 0 0 2 2 2 1 Calcium-binding EGF domain CMV_1a PF12467.8 CBY38660.1 - 0.084 13.2 0.5 0.16 12.3 0.5 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Fzo_mitofusin PF04799.13 CBY38660.1 - 0.25 10.9 1.1 0.48 10.0 1.1 1.4 1 0 0 1 1 1 0 fzo-like conserved region Holin_BhlA PF10960.8 CBY38662.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 BhlA holin family UPF0542 PF15086.6 CBY38662.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 7TMR-DISM_7TM PF07695.11 CBY38662.1 - 0.12 12.3 9.5 0.15 12.0 9.5 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2207 PF09972.9 CBY38662.1 - 0.24 10.1 4.0 0.35 9.6 4.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-C2H2 PF00096.26 CBY38664.1 - 4e-15 55.3 20.2 7.1e-05 23.1 3.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY38664.1 - 1.2e-09 38.1 21.1 1.2e-05 25.5 0.9 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY38664.1 - 5.7e-09 36.1 18.2 0.0016 19.1 2.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 CBY38664.1 - 0.0035 17.9 6.7 0.04 14.5 1.0 3.0 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CBY38664.1 - 0.0083 16.4 3.7 0.76 10.1 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY38664.1 - 0.11 12.9 5.4 5.6 7.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type EGF_CA PF07645.15 CBY38665.1 - 2.1e-47 159.1 187.9 1.4e-09 37.9 3.7 17.4 12 6 6 18 18 18 13 Calcium-binding EGF domain EGF_3 PF12947.7 CBY38665.1 - 1.3e-13 50.8 191.6 4.2e-09 36.5 11.2 18.0 16 2 1 17 17 17 7 EGF domain cEGF PF12662.7 CBY38665.1 - 1.2e-07 31.5 15.5 4e-07 29.8 5.2 12.9 13 1 0 13 13 13 6 Complement Clr-like EGF-like EGF PF00008.27 CBY38665.1 - 0.0049 17.1 5.4 0.0049 17.1 5.4 18.1 18 0 0 18 18 18 5 EGF-like domain FXa_inhibition PF14670.6 CBY38665.1 - 0.019 15.2 3.3 0.019 15.2 3.3 17.5 16 2 1 17 17 17 0 Coagulation Factor Xa inhibitory site Sulfotransfer_2 PF03567.14 CBY38666.1 - 1.2e-25 90.9 6.2 1.7e-25 90.4 2.8 2.2 2 0 0 2 2 2 1 Sulfotransferase family EF-hand_like PF09279.11 CBY38668.1 - 0.026 15.0 0.1 0.031 14.8 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Gly-zipper_Omp PF13488.6 CBY38669.1 - 0.053 13.5 3.1 0.053 13.5 3.1 1.9 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.6 CBY38669.1 - 0.16 11.8 5.8 0.34 10.7 5.8 1.5 1 0 0 1 1 1 0 Glycine-zipper domain SH3_1 PF00018.28 CBY38670.1 - 8.8e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY38670.1 - 1.1e-05 25.2 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY38670.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CG-1 PF03859.16 CBY38670.1 - 0.016 15.0 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 CG-1 domain DUF4660 PF15559.6 CBY38670.1 - 0.034 14.5 2.1 0.081 13.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4660) SH3_3 PF08239.11 CBY38670.1 - 0.052 13.8 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain PALP PF00291.25 CBY38672.1 - 7e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CBY38672.1 - 2.6e-07 31.0 0.0 0.0043 17.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain Sulfotransfer_2 PF03567.14 CBY38673.1 - 2.5e-13 50.5 0.3 2.8e-13 50.4 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.14 CBY38674.1 - 1.1e-14 55.0 0.0 2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family SH3_9 PF14604.6 CBY38676.1 - 8.7e-37 124.8 0.1 6.2e-14 51.6 0.1 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 CBY38676.1 - 2.9e-33 113.2 0.4 2e-11 43.3 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBY38676.1 - 7.2e-31 105.7 0.6 3.1e-13 49.2 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain UQ_con PF00179.26 CBY38677.1 - 4.8e-40 136.4 0.0 6.9e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY38677.1 - 3.2e-07 30.1 0.0 5.6e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY38677.1 - 0.0043 17.3 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA PF00627.31 CBY38677.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain UBA_3 PF09288.10 CBY38677.1 - 0.095 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UBA_4 PF14555.6 CBY38677.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 UBA-like domain Bromodomain PF00439.25 CBY38678.1 - 1.3e-19 70.0 0.1 3e-19 68.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain X PF00739.19 CBY38678.1 - 0.022 14.9 1.2 0.11 12.6 1.2 2.2 1 0 0 1 1 1 0 Trans-activation protein X WSD PF15613.6 CBY38678.1 - 0.33 11.5 4.8 0.15 12.5 0.8 2.7 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif SH2 PF00017.24 CBY38679.1 - 1.5e-13 50.6 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SH3_1 PF00018.28 CBY38679.1 - 4.4e-13 48.6 0.0 1.2e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY38679.1 - 3.5e-11 42.8 0.0 8.4e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY38679.1 - 1e-06 28.3 0.0 3.9e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SNF PF00209.18 CBY38680.1 - 1.2e-192 641.3 28.2 1.4e-192 641.1 28.2 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Trypsin PF00089.26 CBY38681.1 - 4.4e-61 206.5 0.1 6.3e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY38681.1 - 6e-06 27.2 0.0 2.5e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain zf-3CxxC_2 PF17180.4 CBY38682.1 - 1.1e-22 80.5 14.0 1.1e-22 80.5 14.0 4.5 3 3 1 4 4 4 1 Zinc-binding domain FimH_man-bind PF09160.10 CBY38685.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 FimH, mannose binding PorB PF11565.8 CBY38685.1 - 0.021 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B MH2 PF03166.14 CBY38686.1 - 1.7e-29 103.4 1.7 3.6e-29 102.3 1.7 1.6 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY38686.1 - 5.5e-09 36.2 0.8 4.3e-08 33.3 0.8 2.3 1 1 0 1 1 1 1 MH1 domain Pkinase PF00069.25 CBY38687.1 - 2.2e-36 125.6 0.0 7.1e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38687.1 - 8.4e-33 113.7 0.0 1.9e-32 112.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY38687.1 - 2.2e-05 23.4 0.0 4.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY38687.1 - 0.00033 20.1 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY38687.1 - 0.0016 17.4 0.0 0.0068 15.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Dynamin_N PF00350.23 CBY38687.1 - 0.0053 16.8 1.4 0.22 11.6 0.1 3.1 3 0 0 3 3 3 1 Dynamin family APH PF01636.23 CBY38687.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Annexin PF00191.20 CBY38688.1 - 2.4e-11 43.6 0.3 3.2e-11 43.1 0.3 1.2 1 0 0 1 1 1 1 Annexin Imm64 PF15600.6 CBY38688.1 - 0.0046 16.7 0.1 0.0057 16.4 0.1 1.1 1 0 0 1 1 1 1 Immunity protein 64 Sacchrp_dh_C PF16653.5 CBY38689.1 - 2.1e-73 247.7 0.0 3.4e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CBY38689.1 - 4.5e-19 69.0 0.1 7.4e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBY38689.1 - 0.00059 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CBY38689.1 - 0.00078 18.8 0.0 0.038 13.3 0.0 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY38689.1 - 0.0038 17.6 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 CBY38689.1 - 0.022 15.3 1.5 0.27 11.8 0.1 3.1 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase IF2_N PF04760.15 CBY38689.1 - 0.025 14.4 0.0 0.12 12.2 0.0 2.2 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Pyr_redox_2 PF07992.14 CBY38689.1 - 0.027 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 CBY38689.1 - 0.044 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 CBY38689.1 - 0.087 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CBY38689.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain CMAS PF02353.20 CBY38690.1 - 4.6e-13 49.1 1.6 6.4e-13 48.6 1.6 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBY38690.1 - 1.9e-05 24.5 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY38690.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY38690.1 - 0.0092 16.7 0.0 0.015 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY38690.1 - 0.013 16.1 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PFK PF00365.20 CBY38691.1 - 2.3e-32 112.5 0.4 3e-32 112.1 0.4 1.1 1 0 0 1 1 1 1 Phosphofructokinase DENN PF02141.21 CBY38691.1 - 1e-19 71.2 5.2 1.5e-19 70.7 5.2 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CBY38691.1 - 2.8e-10 40.0 1.3 4.1e-10 39.5 1.3 1.2 1 0 0 1 1 1 1 dDENN domain 14-3-3 PF00244.20 CBY38692.1 - 4.2e-107 356.7 2.6 4.8e-107 356.5 2.6 1.0 1 0 0 1 1 1 1 14-3-3 protein CIMR PF00878.18 CBY38693.1 - 1.6e-102 339.5 85.0 3.5e-17 62.8 2.8 16.9 13 6 1 15 15 15 14 Cation-independent mannose-6-phosphate receptor repeat fn2 PF00040.19 CBY38693.1 - 0.078 13.3 10.2 0.44 10.9 10.2 2.5 1 0 0 1 1 1 0 Fibronectin type II domain Ank_2 PF12796.7 CBY38694.1 - 7.1e-20 71.4 0.0 5.1e-09 36.6 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY38694.1 - 7.4e-11 42.1 0.0 7.4e-07 29.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY38694.1 - 8.4e-11 41.1 0.0 0.012 16.1 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CBY38694.1 - 5.6e-07 29.7 0.0 0.16 12.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 CBY38694.1 - 5.8e-07 29.9 0.1 0.0011 19.4 0.0 4.0 2 2 2 4 4 4 2 Ankyrin repeats (many copies) CREPT PF16566.5 CBY38695.1 - 1.4e-11 44.8 2.2 1.4e-11 44.8 2.2 2.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTD_bind PF04818.13 CBY38695.1 - 2.8e-11 44.0 1.1 1.3e-10 42.0 0.0 2.8 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Med19 PF10278.9 CBY38695.1 - 4.3e-05 23.5 1.8 4.3e-05 23.5 1.8 1.8 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 CTK3 PF12243.8 CBY38695.1 - 0.0038 17.2 0.1 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Peptidase_S49_N PF08496.10 CBY38695.1 - 0.53 10.3 11.1 0.26 11.3 6.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thg1C PF14413.6 CBY38695.1 - 2.9 8.0 8.3 1.7 8.8 4.1 2.2 2 0 0 2 2 2 0 Thg1 C terminal domain RNase_PH PF01138.21 CBY38696.1 - 5.2e-21 75.5 0.3 7.2e-21 75.1 0.3 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1415 PF07209.12 CBY38696.1 - 0.027 14.2 0.2 0.073 12.8 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) MOZART1 PF12554.8 CBY38697.1 - 9.9e-14 50.9 0.1 1.3e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Pan3_PK PF18101.1 CBY38699.1 - 2.8e-42 144.0 0.0 5.5e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CBY38699.1 - 1.9e-08 34.0 0.3 4.2e-08 32.9 0.2 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38699.1 - 0.004 16.5 0.1 0.0067 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pro_isomerase PF00160.21 CBY38701.1 - 6.6e-47 159.7 0.3 7.7e-47 159.5 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fzo_mitofusin PF04799.13 CBY38702.1 - 2.2e-32 111.8 0.9 2.8e-32 111.5 0.9 1.1 1 0 0 1 1 1 1 fzo-like conserved region Gp-FAR-1 PF05823.12 CBY38702.1 - 0.0062 16.9 0.6 0.049 14.0 0.9 2.0 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Phasin PF05597.11 CBY38702.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.18 CBY38702.1 - 0.011 15.6 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3810 PF12725.7 CBY38702.1 - 0.037 13.4 0.2 0.045 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) T6PP_N PF18572.1 CBY38702.1 - 0.13 12.1 1.3 0.2 11.5 1.3 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain EHN PF06441.12 CBY38702.1 - 0.19 12.1 2.1 0.4 11.1 2.1 1.6 1 1 0 1 1 1 0 Epoxide hydrolase N terminus YtxH PF12732.7 CBY38702.1 - 0.2 12.2 2.5 2.7 8.6 2.5 2.3 1 1 0 1 1 1 0 YtxH-like protein Frizzled PF01534.17 CBY38703.1 - 3.1e-115 384.7 15.2 3.6e-115 384.5 15.2 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF898 PF05987.13 CBY38703.1 - 0.0096 15.0 0.2 0.0096 15.0 0.2 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF898) Jagunal PF07086.12 CBY38703.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.7 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF2859 PF11072.8 CBY38705.1 - 2.3 8.0 4.9 22 4.8 0.1 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF2859) Pkinase PF00069.25 CBY38706.1 - 1.7e-14 53.8 0.1 4.1e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38706.1 - 6.1e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2079 PF09852.9 CBY38707.1 - 9.4e-05 21.4 1.0 0.00011 21.2 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) DUF3144 PF11342.8 CBY38707.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) CBM_14 PF01607.24 CBY38708.1 - 3.3e-05 23.9 7.9 0.00015 21.9 7.9 2.2 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Sulfotransfer_1 PF00685.27 CBY38710.1 - 3.5e-13 49.6 0.1 5.6e-13 49.0 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY38710.1 - 5.6e-10 40.0 0.0 5e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase family CLIP_SPH_mas PF18398.1 CBY38710.1 - 0.99 9.9 3.3 2.4 8.6 1.6 2.4 2 1 0 2 2 2 0 Clip-domain serine protease homolog masquerade Fibrinogen_C PF00147.18 CBY38711.1 - 7.1e-56 189.5 3.0 1.1e-55 188.8 3.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Met_synt_B12 PF02965.17 CBY38711.1 - 0.093 12.2 1.1 0.18 11.2 1.1 1.4 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain DUF1090 PF06476.12 CBY38711.1 - 1.9 8.7 14.1 1.4 9.0 6.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Nif11 PF07862.11 CBY38711.1 - 3.2 8.1 5.6 0.78 10.1 0.7 2.5 2 0 0 2 2 2 0 Nif11 domain BRK PF07533.16 CBY38712.1 - 4.7e-06 26.1 0.1 2.2e-05 24.0 0.0 2.1 3 0 0 3 3 3 1 BRK domain CHDCT2 PF08074.11 CBY38713.1 - 4.6e-09 36.7 2.0 0.031 14.5 0.0 4.3 4 0 0 4 4 4 2 CHDCT2 (NUC038) domain Myb_DNA-bind_7 PF15963.5 CBY38713.1 - 0.0053 16.6 0.0 0.0053 16.6 0.0 2.8 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBY38713.1 - 0.015 15.4 12.4 5.8 7.2 0.1 4.9 5 0 0 5 5 5 0 Myb-like DNA-binding domain SLIDE PF09111.10 CBY38713.1 - 0.017 15.2 0.1 0.85 9.7 0.0 3.6 4 0 0 4 4 4 0 SLIDE DUF5343 PF17278.2 CBY38713.1 - 0.69 10.0 2.9 6 6.9 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5343) SNF2_N PF00176.23 CBY38714.1 - 2.6e-62 210.6 0.9 4e-62 210.0 0.9 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CBY38714.1 - 2.9e-15 55.9 16.9 2.9e-12 46.3 0.3 3.6 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CBY38714.1 - 1.6e-11 44.5 0.0 5.8e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBY38714.1 - 6.3e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY38714.1 - 3.1e-05 24.3 0.0 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CBY38714.1 - 0.00067 19.4 0.0 0.0053 16.5 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CBY38714.1 - 0.088 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TSP_1 PF00090.19 CBY38716.1 - 8.4e-126 410.1 324.2 6.8e-10 39.0 9.4 20.6 20 0 0 20 20 20 19 Thrombospondin type 1 domain Thiolase_N PF00108.23 CBY38717.1 - 2.3e-43 148.4 0.3 3.9e-43 147.7 0.1 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBY38717.1 - 1.5e-36 124.7 0.1 2.6e-36 124.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBY38717.1 - 1.2e-05 25.0 0.2 0.00027 20.6 0.1 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Latrotoxin_C PF15658.6 CBY38717.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Proteasom_PSMB PF10508.9 CBY38717.1 - 0.21 10.0 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit ACP_syn_III PF08545.10 CBY38717.1 - 0.77 9.6 7.3 5.2 7.0 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Neur_chan_LBD PF02931.23 CBY38718.1 - 2e-25 89.5 0.1 2.6e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY38718.1 - 6e-22 78.9 1.1 9.6e-22 78.2 1.1 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Toxin_6 PF05453.12 CBY38719.1 - 0.68 10.4 7.6 0.15 12.5 2.8 2.3 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family LOH1CR12 PF10158.9 CBY38720.1 - 0.0069 16.4 2.2 0.0069 16.4 2.2 3.8 2 2 3 5 5 5 1 Tumour suppressor protein Glyco_transf_7N PF13733.6 CBY38721.1 - 1.8e-38 131.2 0.1 3.1e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 CBY38721.1 - 1.3e-27 95.2 1.4 2.2e-27 94.5 1.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Rad60-SLD PF11976.8 CBY38721.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.22 CBY38722.1 - 0.001 18.8 0.0 0.087 12.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 CBY38722.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 SET PF00856.28 CBY38723.1 - 1.9e-10 41.4 0.1 4e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 SET domain DUF3788 PF12663.7 CBY38723.1 - 0.014 15.3 0.4 0.027 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) YEATS PF03366.16 CBY38724.1 - 7.2e-22 77.2 0.1 9.4e-22 76.8 0.1 1.1 1 0 0 1 1 1 1 YEATS family MGAT2 PF05060.14 CBY38725.1 - 3.7e-80 269.6 1.5 5.4e-80 269.1 1.5 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) SSF PF00474.17 CBY38726.1 - 1.8e-12 46.8 6.5 1.8e-12 46.8 6.5 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2417 PF10329.9 CBY38726.1 - 0.015 14.7 0.9 0.015 14.7 0.9 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) UPF0547 PF10571.9 CBY38726.1 - 0.12 12.4 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF417 PF04224.12 CBY38726.1 - 1.4 8.4 6.9 0.19 11.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF417 NAD_binding_11 PF14833.6 CBY38727.1 - 2.3e-08 34.3 0.0 2.5e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase An_peroxidase PF03098.15 CBY38729.1 - 4.9e-150 500.6 0.0 2.1e-149 498.5 0.0 1.8 2 0 0 2 2 2 1 Animal haem peroxidase Mucin2_WxxW PF13330.6 CBY38729.1 - 1e-38 132.1 1.3 2.6e-17 63.4 0.0 4.4 5 0 0 5 5 5 2 Mucin-2 protein WxxW repeating region Kinesin PF00225.23 CBY38731.1 - 1e-107 360.0 0.5 1e-107 360.0 0.5 2.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBY38731.1 - 8.1e-22 77.8 0.2 8.1e-22 77.8 0.2 4.1 2 1 2 4 4 4 1 Microtubule binding WD40 PF00400.32 CBY38731.1 - 9e-09 35.8 2.9 0.013 16.4 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat DIX PF00778.17 CBY38732.1 - 2.8e-07 30.3 0.1 9.5e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 DIX domain Axin_b-cat_bind PF08833.10 CBY38732.1 - 4.7e-06 26.6 0.2 0.00013 22.0 0.0 2.4 2 0 0 2 2 2 1 Axin beta-catenin binding domain DUF4367 PF14285.6 CBY38732.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) CRPA PF05745.11 CBY38734.1 - 4.7 7.2 12.5 1.9 8.5 5.4 2.1 1 1 1 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Trypsin PF00089.26 CBY38735.1 - 6e-37 127.6 0.4 1.1e-36 126.7 0.4 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY38735.1 - 0.00011 23.1 0.0 0.00036 21.4 0.0 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain HLH PF00010.26 CBY38736.1 - 1.5e-16 60.0 0.1 1.5e-16 60.0 0.1 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cas9-BH PF16593.5 CBY38736.1 - 0.091 12.5 2.8 0.32 10.7 1.7 2.1 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 TPR_2 PF07719.17 CBY38737.1 - 2.1e-08 33.6 1.1 0.0062 16.6 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY38737.1 - 4.4e-06 26.3 0.9 0.039 13.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY38737.1 - 7.3e-05 23.0 0.1 4.3 7.7 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38737.1 - 0.00031 20.7 0.1 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY38737.1 - 0.00054 20.6 0.0 0.43 11.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY38737.1 - 0.00063 20.3 0.0 1.4 9.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat EPSP_synthase PF00275.20 CBY38737.1 - 0.03 13.0 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TPR_6 PF13174.6 CBY38737.1 - 0.08 13.6 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.15 CBY38739.1 - 3.9e-109 365.8 21.9 4.8e-109 365.5 21.9 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TMEM61 PF15105.6 CBY38739.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM61 protein family Ifi-6-16 PF06140.13 CBY38740.1 - 4.3e-09 36.1 23.6 7.2e-09 35.4 23.6 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family SPATA6 PF14909.6 CBY38742.1 - 8.3e-44 149.1 0.0 1.6e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-assoc protein 6 DUF1654 PF07867.11 CBY38742.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) RRM_1 PF00076.22 CBY38743.1 - 7.8e-08 32.0 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5-nucleotidase PF06189.12 CBY38744.1 - 3.2e-59 200.0 0.0 3.6e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 5'-nucleotidase Acid_PPase PF12689.7 CBY38744.1 - 0.0089 15.9 0.1 0.084 12.7 0.0 2.3 1 1 1 3 3 3 1 Acid Phosphatase Pkinase PF00069.25 CBY38746.1 - 5.1e-09 35.9 0.0 6.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38746.1 - 5.4e-06 25.9 0.0 6.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase GPHH PF16905.5 CBY38746.1 - 0.021 14.6 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 CBY38747.1 - 1.2e-16 58.9 18.0 0.0007 19.0 0.1 6.5 6 2 1 7 7 7 5 EF hand EF-hand_7 PF13499.6 CBY38747.1 - 5.2e-15 55.7 19.3 1.7e-08 34.8 0.9 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY38747.1 - 2.7e-14 51.9 14.0 0.0042 16.5 0.1 6.0 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBY38747.1 - 1.3e-10 40.3 15.4 0.14 12.2 0.1 6.3 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 CBY38747.1 - 2e-07 30.8 14.7 0.026 14.4 0.2 5.4 5 0 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY38747.1 - 1.1e-05 25.8 15.2 0.0015 18.8 0.7 3.8 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.13 CBY38747.1 - 7.8e-05 22.5 0.3 0.00017 21.4 0.3 1.5 1 0 0 1 1 1 1 Methyladenine glycosylase EF-hand_10 PF14788.6 CBY38747.1 - 0.024 14.5 0.3 0.024 14.5 0.3 4.4 5 1 1 6 6 6 0 EF hand Unstab_antitox PF09720.10 CBY38747.1 - 2.5 8.2 6.2 5.6 7.1 1.1 3.3 3 0 0 3 3 3 0 Putative addiction module component DUF2072 PF09845.9 CBY38748.1 - 0.13 12.6 0.1 0.35 11.1 0.0 1.8 1 1 0 1 1 1 0 Zn-ribbon containing protein PDEase_I PF00233.19 CBY38750.1 - 0.00043 20.1 2.1 0.00054 19.7 2.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SIL1 PF16782.5 CBY38750.1 - 0.22 10.7 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 zf-Tim10_DDP PF02953.15 CBY38753.1 - 2.9e-16 58.8 7.1 3.7e-16 58.5 7.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3213 PF11491.8 CBY38753.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3213) RabGAP-TBC PF00566.18 CBY38754.1 - 6.3e-46 156.7 0.3 6.3e-46 156.7 0.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SlyX PF04102.12 CBY38755.1 - 0.037 14.6 0.6 0.74 10.5 1.0 3.0 2 0 0 2 2 2 0 SlyX Mg296 PF09644.10 CBY38755.1 - 0.048 13.8 0.3 0.17 12.0 0.3 1.9 1 0 0 1 1 1 0 Mg296 protein Lge1 PF11488.8 CBY38755.1 - 8.7 6.6 7.8 3.6 7.8 2.8 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Myosin_tail_1 PF01576.19 CBY38756.1 - 7.8e-26 90.2 116.1 4.4e-23 81.1 76.2 3.2 1 1 2 3 3 3 3 Myosin tail Myosin_head PF00063.21 CBY38757.1 - 1.6e-60 205.1 0.0 1.9e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) CBFD_NFYB_HMF PF00808.23 CBY38759.1 - 1.6e-14 53.9 0.7 2.3e-14 53.4 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY38759.1 - 0.00012 22.5 0.2 0.00012 22.5 0.2 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CBY38759.1 - 0.03 14.4 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rap_GAP PF02145.15 CBY38760.1 - 2.1e-54 183.9 0.1 3.9e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.24 CBY38760.1 - 1.8e-08 34.6 0.1 4e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY38760.1 - 1e-06 28.5 0.0 2.7e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY38760.1 - 0.017 15.5 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Rootletin PF15035.6 CBY38760.1 - 0.031 14.3 1.4 0.074 13.1 1.4 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lzipper-MIP1 PF14389.6 CBY38760.1 - 0.078 13.3 0.6 0.29 11.5 0.6 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 CBY38760.1 - 1.1 9.0 3.1 2 8.2 2.0 2.0 2 0 0 2 2 2 0 Septum formation initiator UQ_con PF00179.26 CBY38762.1 - 2.5e-48 163.3 0.1 2.7e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY38762.1 - 8.9e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY38762.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CBY38762.1 - 0.004 17.4 0.1 0.0048 17.2 0.1 1.4 1 1 0 1 1 1 1 RWD domain Mob1_phocein PF03637.17 CBY38763.1 - 1.4e-23 83.7 0.1 1.8e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family PMP22_Claudin PF00822.20 CBY38764.1 - 1.9e-05 24.6 3.2 2.4e-05 24.3 3.2 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Anticodon_1 PF08264.13 CBY38765.1 - 0.027 14.4 0.1 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA ATP-gua_Ptrans PF00217.19 CBY38766.1 - 3e-46 157.6 0.1 1.1e-31 110.0 0.0 2.1 1 1 1 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY38766.1 - 1.2e-18 67.2 0.0 3e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Galactosyl_T PF01762.21 CBY38768.1 - 2.4e-12 47.1 0.1 1e-11 45.1 0.1 1.8 1 1 0 1 1 1 1 Galactosyltransferase Phage_integrase PF00589.22 CBY38772.1 - 0.029 14.1 0.2 0.081 12.7 0.1 2.0 2 1 0 2 2 2 0 Phage integrase family RVT_connect PF06815.13 CBY38774.1 - 0.027 14.7 0.1 1.8 8.8 0.1 2.9 2 0 0 2 2 2 0 Reverse transcriptase connection domain LEM PF03020.15 CBY38777.1 - 2.4e-18 65.4 0.1 2.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 LEM domain SPT6_acidic PF14632.6 CBY38777.1 - 0.038 14.6 1.8 0.038 14.6 1.8 1.9 1 1 1 2 2 2 0 Acidic N-terminal SPT6 RIFIN PF02009.16 CBY38777.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Rifin AcrZ PF10766.9 CBY38777.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Golgin_A5 PF09787.9 CBY38778.1 - 0.00053 19.5 14.7 0.00053 19.5 14.7 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF4763 PF15960.5 CBY38778.1 - 0.0014 18.0 5.7 0.0014 18.0 5.7 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4763) GAS PF13851.6 CBY38778.1 - 0.0023 17.3 8.0 0.0023 17.3 8.0 3.6 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 CBY38778.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 CBY38778.1 - 0.31 11.4 0.2 0.31 11.4 0.2 4.6 4 1 1 5 5 5 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 CBY38778.1 - 0.39 10.7 47.0 0.11 12.5 2.5 3.5 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3463 PF11946.8 CBY38778.1 - 1.4 8.7 3.9 1.1 9.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) LPP PF04728.13 CBY38778.1 - 4.7 7.7 17.7 1.7 9.1 0.2 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper APG6_N PF17675.1 CBY38778.1 - 6.9 7.2 51.0 0.31 11.6 10.8 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region Atg8 PF02991.16 CBY38779.1 - 6.2e-31 106.7 0.0 7.2e-31 106.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY38779.1 - 0.0027 18.1 0.0 0.0031 17.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 E1_DerP2_DerF2 PF02221.15 CBY38780.1 - 1.4e-06 28.8 0.1 8e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 ML domain Pkinase PF00069.25 CBY38781.1 - 4.7e-26 91.7 0.0 5.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38781.1 - 2.5e-12 46.6 0.0 1.1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY38781.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY38781.1 - 0.014 14.9 0.2 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 CBY38781.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PS_Dcarbxylase PF02666.15 CBY38782.1 - 1.2e-17 64.1 0.0 1.3e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Maelstrom PF13017.6 CBY38784.1 - 3.3e-23 82.5 1.3 6.7e-23 81.5 1.3 1.4 1 0 0 1 1 1 1 piRNA pathway germ-plasm component HMG_box_2 PF09011.10 CBY38784.1 - 6.5e-07 29.9 0.1 1.9e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain zf-NPL4 PF05020.15 CBY38784.1 - 0.022 14.9 1.0 0.022 14.9 1.0 2.0 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region HMG_box PF00505.19 CBY38784.1 - 0.043 14.2 0.3 0.043 14.2 0.3 2.3 2 1 1 3 3 3 0 HMG (high mobility group) box Abhydrolase_3 PF07859.13 CBY38785.1 - 3.2e-41 141.5 0.2 7.8e-30 104.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CBY38785.1 - 2e-07 30.3 0.2 1e-06 28.0 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family TMEM232 PF15877.5 CBY38786.1 - 7.3e-07 28.5 0.7 1.2e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein family 232 LRR_4 PF12799.7 CBY38788.1 - 7.1e-11 42.2 7.8 5.8e-06 26.6 0.0 4.9 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY38788.1 - 1.5e-06 27.9 2.8 1e-05 25.2 0.3 3.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 CBY38788.1 - 0.0043 16.6 1.2 0.02 14.4 0.1 2.4 1 1 2 3 3 3 2 Leucine-rich repeat DUF966 PF06136.13 CBY38788.1 - 0.01 15.6 2.6 0.014 15.1 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FoP_duplication PF13865.6 CBY38788.1 - 0.081 13.5 0.1 0.081 13.5 0.1 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 LRR_6 PF13516.6 CBY38788.1 - 0.094 12.8 0.1 46 4.4 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY38788.1 - 0.45 11.3 5.2 76 4.5 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat FHA PF00498.26 CBY38789.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY38789.1 - 3.9e-05 23.9 0.0 0.0017 18.6 0.0 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RabGAP-TBC PF00566.18 CBY38790.1 - 4.4e-46 157.2 0.0 9.7e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CBY38790.1 - 2.6e-18 66.0 1.8 1.8e-09 37.5 0.5 2.8 2 1 0 2 2 2 2 GRAM domain DUF2301 PF10063.9 CBY38790.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Glycos_transf_4 PF00953.21 CBY38791.1 - 3.8e-34 118.0 7.3 3.8e-34 118.0 7.3 1.8 3 0 0 3 3 3 1 Glycosyl transferase family 4 LIM PF00412.22 CBY38792.1 - 1.9e-36 124.1 39.0 3.3e-14 52.8 8.4 3.5 4 0 0 4 4 4 3 LIM domain PDZ PF00595.24 CBY38792.1 - 3.3e-11 43.4 0.0 6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY38792.1 - 0.00081 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY38792.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Dynamin_M PF01031.20 CBY38793.1 - 6e-96 321.0 3.1 6e-96 321.0 3.1 2.4 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 CBY38793.1 - 1.7e-55 187.6 0.1 9.7e-55 185.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 CBY38793.1 - 1.8e-22 79.3 3.9 1.8e-22 79.3 3.9 2.8 3 0 0 3 3 3 1 Dynamin GTPase effector domain PH PF00169.29 CBY38793.1 - 9.1e-09 35.8 0.2 1.8e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.23 CBY38793.1 - 0.00015 21.8 0.0 0.00049 20.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DASH_Duo1 PF08651.10 CBY38793.1 - 0.019 14.7 0.6 3.7 7.4 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF3206 PF11472.8 CBY38793.1 - 0.034 14.1 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) AAA_28 PF13521.6 CBY38793.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PI-PLC-X PF00388.19 CBY38795.1 - 1.1e-30 106.1 0.0 1.8e-29 102.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain ETRAMP PF09716.10 CBY38796.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.2 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) WD40 PF00400.32 CBY38797.1 - 1.8e-06 28.5 7.7 0.88 10.5 0.3 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY38797.1 - 0.0032 17.7 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain ZU5 PF00791.20 CBY38799.1 - 1.1e-35 121.9 0.0 1.4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 ZU5 domain PaO PF08417.12 CBY38800.1 - 0.2 11.8 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Pheophorbide a oxygenase 2OG-FeII_Oxy_2 PF13532.6 CBY38803.1 - 1.4e-28 100.4 0.0 1.7e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.9 CBY38803.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe dioxygenase Pkinase PF00069.25 CBY38804.1 - 1.3e-69 234.5 0.0 1.3e-69 234.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38804.1 - 1.8e-33 115.9 0.0 3.4e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY38804.1 - 1.9e-05 23.8 0.0 1.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 CBY38804.1 - 0.021 14.1 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CBY38804.1 - 0.047 13.6 0.0 0.22 11.4 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family NARP1 PF12569.8 CBY38804.1 - 4.8 6.0 24.2 9.1 5.1 24.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IPP-2 PF04979.14 CBY38805.1 - 2.3e-22 80.2 10.0 7.9e-22 78.4 9.7 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) MRP-S23 PF10484.9 CBY38805.1 - 0.074 13.3 1.2 0.48 10.7 1.2 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 Chlorophyllase2 PF12740.7 CBY38805.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme HYLS1_C PF15311.6 CBY38807.1 - 1e-25 90.3 1.1 1e-25 90.3 1.1 1.9 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus DUF2510 PF10708.9 CBY38807.1 - 0.049 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Allexi_40kDa PF05549.11 CBY38807.1 - 0.1 12.1 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein HEAT PF02985.22 CBY38808.1 - 0.027 14.7 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 HEAT repeat Adaptin_N PF01602.20 CBY38808.1 - 0.14 10.7 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region Adaptin_N PF01602.20 CBY38809.1 - 0.048 12.2 0.3 2.5 6.6 0.0 2.4 1 1 0 2 2 2 0 Adaptin N terminal region RNase_T PF00929.24 CBY38810.1 - 3.1e-09 37.6 0.0 4.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease MBOAT PF03062.19 CBY38811.1 - 1.2e-44 153.1 5.0 2.3e-44 152.2 5.0 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Fib_alpha PF08702.10 CBY38812.1 - 0.014 15.6 6.8 0.014 15.6 6.8 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SHE3 PF17078.5 CBY38812.1 - 1.5 8.4 37.7 0.019 14.7 21.6 2.9 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 CBY38812.1 - 5.6 6.3 42.4 4 6.8 22.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 CBY38812.1 - 6.8 6.7 7.6 2.6 8.1 0.6 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Shugoshin_N PF07558.11 CBY38813.1 - 0.013 15.4 3.1 0.013 15.4 3.1 6.7 7 0 0 7 7 7 0 Shugoshin N-terminal coiled-coil region WD40 PF00400.32 CBY38814.1 - 0.0026 18.6 0.2 0.0075 17.1 0.1 1.7 1 1 0 2 2 2 1 WD domain, G-beta repeat LVIVD PF08309.11 CBY38814.1 - 0.011 15.1 0.4 0.075 12.4 0.5 2.0 2 0 0 2 2 2 0 LVIVD repeat eIF2A PF08662.11 CBY38814.1 - 0.055 13.3 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A bZIP_1 PF00170.21 CBY38815.1 - 0.00013 22.0 8.0 0.00021 21.3 8.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY38815.1 - 0.00047 20.2 7.9 0.00086 19.3 7.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper GIT_CC PF16559.5 CBY38815.1 - 0.0023 17.8 0.4 0.0049 16.7 0.4 1.5 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 CBY38815.1 - 0.0029 18.0 4.1 0.0031 17.8 1.6 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBY38815.1 - 0.017 14.9 1.0 0.035 13.9 0.8 1.7 1 1 1 2 2 2 0 Septum formation initiator DUF641 PF04859.12 CBY38815.1 - 0.021 15.2 2.5 0.029 14.7 2.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMCO5 PF14992.6 CBY38815.1 - 0.037 13.6 3.8 0.041 13.5 3.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 CBY38815.1 - 0.044 13.8 1.6 0.065 13.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 CBY38815.1 - 0.056 13.5 1.6 0.12 12.5 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Pox_G5 PF04599.12 CBY38815.1 - 0.09 11.8 2.7 0.11 11.5 2.7 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein WD40 PF00400.32 CBY38816.1 - 1.6e-07 31.9 0.1 0.0003 21.5 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40_like PF17005.5 CBY38816.1 - 6.9e-05 22.3 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 CBY38816.1 - 8.1e-05 22.9 0.0 0.072 13.4 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HALZ PF02183.18 CBY38816.1 - 0.22 11.7 0.5 0.65 10.3 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sld5 PF05916.11 CBY38818.1 - 2.8e-12 47.1 0.2 4.4e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein OST-HTH PF12872.7 CBY38818.1 - 0.0024 17.6 0.0 0.007 16.2 0.0 1.9 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Chromo PF00385.24 CBY38819.1 - 2.2e-39 133.1 15.7 3.1e-12 46.2 0.0 4.4 4 0 0 4 4 4 4 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY38819.1 - 0.0068 16.3 11.5 0.068 13.1 0.3 3.6 2 2 0 2 2 2 2 RNA binding activity-knot of a chromodomain PWWP PF00855.17 CBY38819.1 - 2.1 8.8 23.4 0.21 12.0 1.5 4.0 1 1 2 3 3 3 0 PWWP domain NDUFB11 PF17250.2 CBY38819.1 - 9.1 7.0 7.9 0.28 11.9 0.5 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit CBM46 PF18448.1 CBY38820.1 - 0.12 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain DUF525 PF04379.14 CBY38821.1 - 4.9e-24 84.4 0.0 7.5e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 ApaG domain Profilin PF00235.19 CBY38822.1 - 2.1e-10 41.0 0.0 2.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Profilin Endotoxin_N PF03945.14 CBY38823.1 - 0.0031 17.2 0.4 0.0086 15.8 0.4 1.8 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain UPF0054 PF02130.17 CBY38823.1 - 0.12 12.2 4.5 0.57 10.0 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized protein family UPF0054 Trypsin PF00089.26 CBY38825.1 - 9.6e-15 55.0 1.0 1.1e-14 54.8 1.0 1.0 1 0 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.19 CBY38825.1 - 0.12 11.6 0.3 0.13 11.5 0.3 1.0 1 0 0 1 1 1 0 Peptidase family C4 Cupin_8 PF13621.6 CBY38826.1 - 1.1e-20 74.5 0.1 1.5e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY38826.1 - 5.8e-07 29.3 0.0 5.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 CBY38826.1 - 0.005 17.3 0.0 0.028 14.9 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBY38826.1 - 0.0059 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain GYF PF02213.16 CBY38827.1 - 0.00078 19.1 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 GYF domain FAM221 PF14753.6 CBY38829.1 - 2.3e-78 262.3 11.0 2.6e-78 262.1 11.0 1.0 1 0 0 1 1 1 1 Protein FAM221A/B DUF1184 PF06683.11 CBY38829.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) zf-H2C2_2 PF13465.6 CBY38829.1 - 2 9.0 10.2 2 9.0 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain NPH3 PF03000.14 CBY38830.1 - 0.0058 16.3 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 NPH3 family LRR_8 PF13855.6 CBY38831.1 - 2.5e-09 36.7 6.0 1.9e-05 24.3 0.5 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY38831.1 - 2.8e-07 30.7 11.3 0.0028 18.0 0.7 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY38831.1 - 2.6e-06 27.2 8.0 0.49 11.2 1.0 4.8 4 1 0 4 4 4 2 Leucine Rich Repeat DEP PF00610.21 CBY38831.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_9 PF14580.6 CBY38831.1 - 0.1 12.1 0.3 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeat GDP_Man_Dehyd PF16363.5 CBY38832.1 - 3.9e-55 187.6 0.0 4.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBY38832.1 - 4.8e-52 176.8 0.0 5.9e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBY38832.1 - 4.4e-17 62.0 0.0 3.8e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CBY38832.1 - 8.5e-16 57.9 0.0 3.4e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CBY38832.1 - 5e-10 39.6 0.0 8.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CBY38832.1 - 2.2e-08 33.6 0.0 3.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CBY38832.1 - 6.2e-08 32.1 0.0 8.3e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CBY38832.1 - 1.9e-07 31.2 0.0 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CBY38832.1 - 2.3e-06 27.2 0.1 9.9e-06 25.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CBY38832.1 - 4.1e-06 26.5 0.1 0.0036 16.9 0.0 2.4 2 1 0 2 2 2 2 NmrA-like family Sacchrp_dh_NADP PF03435.18 CBY38832.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CBY38832.1 - 0.2 11.2 1.0 0.62 9.6 1.0 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PPTA PF01239.22 CBY38833.1 - 5.3e-09 35.5 5.3 0.00041 20.0 0.8 3.4 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat MINDY_DUB PF04424.13 CBY38833.1 - 0.064 13.3 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 MINDY deubiquitinase PRANC PF09372.10 CBY38833.1 - 1.1 9.6 4.6 6.6 7.1 0.4 2.7 1 1 2 3 3 3 0 PRANC domain Thioredoxin_4 PF13462.6 CBY38834.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin CYYR1 PF10873.8 CBY38835.1 - 2 8.8 7.4 0.84 10.1 1.4 2.1 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 TERB2 PF15101.6 CBY38836.1 - 0.039 14.0 2.7 0.052 13.6 2.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Laminin_EGF PF00053.24 CBY38837.1 - 4.6e-107 350.0 273.0 1e-10 41.5 16.3 14.1 14 0 0 14 14 14 13 Laminin EGF domain Laminin_N PF00055.17 CBY38837.1 - 5.4e-66 222.5 0.0 5.4e-66 222.5 0.0 2.7 3 0 0 3 3 3 1 Laminin N-terminal (Domain VI) F5_F8_type_C PF00754.25 CBY38837.1 - 4.6e-05 23.5 0.3 0.0001 22.4 0.3 1.6 1 0 0 1 1 1 1 F5/8 type C domain Sushi PF00084.20 CBY38839.1 - 0.00039 21.0 19.9 0.069 13.8 4.4 3.6 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) DUF3391 PF11871.8 CBY38839.1 - 0.09 13.3 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Antistasin PF02822.14 CBY38839.1 - 4.6 8.0 9.9 93 3.8 0.2 4.4 3 1 0 3 3 3 0 Antistasin family Sushi PF00084.20 CBY38840.1 - 7.1e-05 23.3 16.6 0.0087 16.6 0.9 3.3 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) EGF_3 PF12947.7 CBY38841.1 - 2.8e-19 69.0 88.3 1.7e-06 28.1 16.6 7.2 7 0 0 7 7 7 6 EGF domain EGF_MSP1_1 PF12946.7 CBY38841.1 - 6.3e-10 38.9 74.4 4.3e-07 29.9 11.6 6.7 6 0 0 6 6 6 5 MSP1 EGF domain 1 EGF PF00008.27 CBY38841.1 - 1.1e-06 28.8 60.2 0.0028 17.9 3.9 7.1 6 1 0 6 6 6 5 EGF-like domain EGF_CA PF07645.15 CBY38841.1 - 0.00014 22.0 91.2 0.011 16.0 9.2 7.9 5 2 2 7 7 7 4 Calcium-binding EGF domain cEGF PF12662.7 CBY38841.1 - 0.75 9.8 49.2 0.12 12.3 3.6 6.2 6 0 0 6 6 6 0 Complement Clr-like EGF-like Thioredoxin PF00085.20 CBY38842.1 - 5.5e-64 212.6 0.0 3.1e-31 107.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY38842.1 - 1.8e-40 138.8 0.0 1.3e-35 123.0 0.1 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY38842.1 - 1.8e-09 38.0 0.1 0.0053 17.2 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY38842.1 - 8.8e-09 35.4 0.0 0.0026 17.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CBY38842.1 - 2.1e-07 30.9 1.4 0.031 14.2 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family Thioredoxin_8 PF13905.6 CBY38842.1 - 6.2e-07 29.7 0.0 0.052 13.9 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CBY38842.1 - 7e-07 28.9 0.0 0.064 12.6 0.0 3.3 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 CBY38842.1 - 0.00048 19.9 2.1 1.5 8.5 0.0 3.8 4 0 0 4 4 4 1 Redoxin Thioredoxin_4 PF13462.6 CBY38842.1 - 0.0074 16.5 0.1 0.62 10.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 CBY38842.1 - 0.061 13.3 0.4 23 5.0 0.0 3.9 4 0 0 4 4 4 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 CBY38842.1 - 0.085 12.5 0.0 11 5.6 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin OTU PF02338.19 CBY38843.1 - 1.6e-23 83.6 1.2 3.6e-23 82.4 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Rap_GAP PF02145.15 CBY38844.1 - 5.8e-54 182.5 0.1 1.1e-53 181.6 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PDZ PF00595.24 CBY38844.1 - 1.6e-08 34.8 0.1 3.6e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY38844.1 - 9.4e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY38844.1 - 0.015 15.6 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Rootletin PF15035.6 CBY38844.1 - 0.029 14.4 1.5 0.071 13.1 1.5 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Lzipper-MIP1 PF14389.6 CBY38844.1 - 0.068 13.5 0.6 0.26 11.6 0.6 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 CBY38844.1 - 0.96 9.3 3.1 1.8 8.4 2.0 2.0 2 0 0 2 2 2 0 Septum formation initiator TPR_2 PF07719.17 CBY38845.1 - 2.2e-06 27.3 1.0 0.0012 18.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY38845.1 - 7.4e-06 25.6 1.3 0.00061 19.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY38845.1 - 1.3e-05 24.8 0.1 0.51 10.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY38845.1 - 0.00062 20.4 0.6 0.22 12.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY38845.1 - 0.0048 17.2 0.5 2.5 8.4 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38845.1 - 0.0066 16.6 0.4 5.8 7.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Rx_N PF18052.1 CBY38845.1 - 0.13 12.6 0.3 0.29 11.4 0.3 1.6 1 0 0 1 1 1 0 Rx N-terminal domain TPR_16 PF13432.6 CBY38845.1 - 0.27 11.9 1.8 5.5 7.7 0.1 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY38845.1 - 0.43 11.1 4.1 93 3.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Phospholip_A2_1 PF00068.19 CBY38847.1 - 1.6e-15 57.5 7.6 1.6e-15 57.5 7.6 1.9 2 0 0 2 2 2 1 Phospholipase A2 EGF_3 PF12947.7 CBY38848.1 - 2.4e-05 24.4 10.9 2.4e-05 24.4 10.9 3.1 3 0 0 3 3 3 2 EGF domain EGF PF00008.27 CBY38848.1 - 0.00054 20.2 6.7 0.00054 20.2 6.7 3.7 3 1 0 3 3 3 2 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY38848.1 - 4.6 7.6 14.8 1.9 8.8 6.5 3.0 2 0 0 2 2 2 0 Pvs28 EGF domain UBA_4 PF14555.6 CBY38849.1 - 6.2e-05 22.7 0.1 0.00014 21.6 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain Homeobox_KN PF05920.11 CBY38850.1 - 7e-15 54.7 0.3 7e-15 54.7 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CBY38850.1 - 2.4e-07 30.5 1.8 4.1e-07 29.7 1.8 1.4 1 0 0 1 1 1 1 Homeodomain MRP-S32 PF10210.9 CBY38850.1 - 0.056 14.0 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 CCD48 PF15799.5 CBY38851.1 - 0.00054 18.4 3.4 0.0006 18.3 3.4 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 APC_N_CC PF16689.5 CBY38851.1 - 0.027 14.5 1.0 0.027 14.5 1.0 2.5 3 1 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain SKA1 PF07160.12 CBY38851.1 - 0.11 12.4 18.4 0.12 12.2 18.4 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 RR_TM4-6 PF06459.12 CBY38851.1 - 0.21 11.4 17.1 0.24 11.2 17.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CBY38851.1 - 0.78 9.9 7.5 0.9 9.6 7.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 CBY38851.1 - 1.1 8.2 7.1 1.3 7.9 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CBY38851.1 - 1.2 7.8 8.7 1.5 7.5 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Coilin_N PF15862.5 CBY38851.1 - 1.3 8.9 14.6 1.5 8.6 14.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus DUF2052 PF09747.9 CBY38851.1 - 1.3 9.1 10.5 1.6 8.8 10.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Fmp27_WPPW PF10359.9 CBY38851.1 - 1.4 7.7 10.1 1.7 7.4 10.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain YabA PF06156.13 CBY38851.1 - 1.7 9.4 8.8 5.9 7.6 8.8 1.9 1 1 0 1 1 1 0 Initiation control protein YabA GAGA_bind PF06217.12 CBY38851.1 - 3.2 8.0 14.1 3.6 7.8 14.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4407 PF14362.6 CBY38851.1 - 3.4 7.0 14.8 4.2 6.6 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CBY38851.1 - 3.6 7.6 6.3 4 7.4 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 CBY38851.1 - 5.5 7.0 17.4 6.7 6.7 17.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CBY38851.1 - 6.5 5.4 10.6 6.9 5.3 10.6 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CBY38851.1 - 9.1 5.4 5.0 9.6 5.3 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cytomega_UL84 PF06284.11 CBY38851.1 - 9.3 4.6 6.5 9.1 4.6 6.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FGF-BP1 PF06473.12 CBY38851.1 - 9.6 6.0 16.8 14 5.5 16.8 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Med16 PF11635.8 CBY38852.1 - 0.00015 19.9 2.6 0.0018 16.3 0.3 2.2 2 1 0 2 2 2 2 Mediator complex subunit 16 Herpes_VP19C PF03327.14 CBY38852.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C DUF5453 PF17534.2 CBY38853.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF2717 PF10911.8 CBY38853.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) DEAD PF00270.29 CBY38854.1 - 1.5e-40 138.9 0.3 7.8e-40 136.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY38854.1 - 1.9e-25 89.3 0.7 4.7e-23 81.6 0.2 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBY38854.1 - 2.3e-06 27.7 0.1 5e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY38854.1 - 9.1e-06 25.2 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit REF PF05755.12 CBY38854.1 - 0.028 14.3 0.1 4.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) GRIM-19 PF06212.12 CBY38855.1 - 1.6e-16 60.4 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein DnaT PF17948.1 CBY38855.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 DnaT DNA-binding domain Cauli_DNA-bind PF03310.13 CBY38855.1 - 0.16 12.0 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein zf-3CxxC_2 PF17180.4 CBY38856.1 - 1.7e-19 70.3 10.4 2.8e-19 69.6 10.4 1.3 1 0 0 1 1 1 1 Zinc-binding domain RNA_pol_Rpb2_5 PF04567.17 CBY38856.1 - 0.12 13.0 0.1 2.6 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 UPF0515 PF15135.6 CBY38856.1 - 0.52 9.6 8.4 0.79 9.0 8.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 MFS_1 PF07690.16 CBY38858.1 - 1.8e-14 53.5 9.5 1.2e-13 50.8 6.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY38859.1 - 5e-22 78.4 12.3 7.2e-22 77.9 12.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY38859.1 - 1.6e-13 50.3 43.5 7.8e-13 48.1 19.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY38859.1 - 0.00018 20.5 3.4 0.00018 20.5 3.4 2.2 2 0 0 2 2 2 1 MFS_1 like family Gram_pos_anchor PF00746.21 CBY38859.1 - 0.15 12.0 8.4 3.4 7.7 1.0 2.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Carn_acyltransf PF00755.20 CBY38860.1 - 8e-118 394.6 4.5 6.1e-116 388.4 4.5 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M18 PF02127.15 CBY38863.1 - 8e-112 374.2 0.0 9.7e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sulfotransfer_2 PF03567.14 CBY38864.1 - 8.3e-06 25.9 0.9 1.2e-05 25.4 0.9 1.3 1 0 0 1 1 1 1 Sulfotransferase family CHORD PF04968.12 CBY38865.1 - 0.00065 20.4 0.6 0.00065 20.4 0.6 1.9 2 0 0 2 2 2 1 CHORD BTK PF00779.19 CBY38865.1 - 0.068 13.0 0.8 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 BTK motif Ion_trans PF00520.31 CBY38866.1 - 1e-43 149.4 30.3 4.9e-33 114.4 17.8 2.2 2 0 0 2 2 2 2 Ion transport protein DUF2207 PF09972.9 CBY38866.1 - 6.6 5.4 8.9 6.1 5.5 0.0 3.3 2 2 0 3 3 3 0 Predicted membrane protein (DUF2207) BRO1 PF03097.18 CBY38867.1 - 6.8e-41 140.4 2.4 8.4e-41 140.1 2.4 1.0 1 0 0 1 1 1 1 BRO1-like domain Fringe PF02434.16 CBY38868.1 - 1.7e-42 145.6 0.0 5.8e-40 137.3 0.0 2.4 2 1 0 2 2 2 2 Fringe-like Glycos_transf_2 PF00535.26 CBY38868.1 - 0.0046 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CBY38868.1 - 0.019 14.5 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CBY38868.1 - 0.14 12.0 0.0 2 8.2 0.0 2.2 1 1 1 2 2 2 0 Glycosyltransferase like family 2 AbbA_antirepres PF14156.6 CBY38869.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Antirepressor AbbA COQ9 PF08511.11 CBY38870.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 COQ9 DUF4934 PF16288.5 CBY38872.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Homeodomain PF00046.29 CBY38873.1 - 1.2e-16 60.3 2.0 2e-16 59.5 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY38873.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.3 2 0 0 2 2 2 0 Homeobox KN domain COX14 PF14880.6 CBY38874.1 - 0.0041 16.9 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly TMEMspv1-c74-12 PF11044.8 CBY38874.1 - 0.022 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein OAD_gamma PF04277.13 CBY38874.1 - 0.033 14.8 0.2 0.043 14.4 0.2 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pro-kuma_activ PF09286.11 CBY38875.1 - 5.8e-19 68.8 0.0 9.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CBY38875.1 - 8.5e-05 22.0 0.0 0.00039 19.8 0.0 1.9 1 1 1 2 2 2 1 Subtilase family Collagen PF01391.18 CBY38876.1 - 5.7e-07 29.2 14.1 7.5e-07 28.8 14.1 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Antifungal_pept PF11410.8 CBY38876.1 - 0.41 10.6 3.7 0.17 11.8 1.2 1.8 2 1 0 2 2 2 0 Antifungal peptide WD40 PF00400.32 CBY38877.1 - 2.6e-05 24.9 7.3 0.04 14.8 0.1 5.7 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY38877.1 - 0.00047 20.4 0.2 0.87 9.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY38877.1 - 0.00088 18.3 0.2 0.051 12.5 0.0 3.1 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein p25-alpha PF05517.12 CBY38877.1 - 1.4 9.1 5.7 2.9 8.0 5.7 1.4 1 0 0 1 1 1 0 p25-alpha PhoPQ_related PF10142.9 CBY38878.1 - 1.5e-93 313.4 0.7 1.9e-93 313.1 0.7 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Hydrolase_4 PF12146.8 CBY38878.1 - 0.0081 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY38878.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY38878.1 - 0.11 12.0 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family RPN13_C PF16550.5 CBY38878.1 - 0.2 11.9 0.0 0.58 10.3 0.0 1.7 2 0 0 2 2 2 0 UCH-binding domain PRA1 PF03208.19 CBY38879.1 - 4.3e-26 91.3 0.3 5.4e-26 90.9 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein 2TM PF13239.6 CBY38879.1 - 7.4 7.0 7.4 38 4.7 7.4 2.0 1 1 0 1 1 1 0 2TM domain Lectin_C PF00059.21 CBY38880.1 - 2e-05 25.3 1.9 4.1e-05 24.3 1.9 1.6 1 0 0 1 1 1 1 Lectin C-type domain IQ PF00612.27 CBY38884.1 - 1.6e-21 74.0 1.2 9.8e-06 24.9 0.0 3.7 4 0 0 4 4 4 3 IQ calmodulin-binding motif RIIa PF02197.17 CBY38884.1 - 3.4e-09 36.2 0.2 5.6e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Prefoldin_3 PF13758.6 CBY38884.1 - 0.92 9.6 5.8 22 5.2 0.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit NADH_B2 PF14813.6 CBY38885.1 - 0.016 15.0 0.9 0.039 13.7 0.9 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 CDV3 PF15359.6 CBY38885.1 - 0.12 12.9 0.7 0.21 12.0 0.7 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 V_ATPase_I PF01496.19 CBY38886.1 - 0.014 13.3 3.9 0.017 13.1 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4576 PF15144.6 CBY38886.1 - 0.11 12.4 0.6 0.21 11.5 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) CPSF100_C PF13299.6 CBY38886.1 - 1.6 8.9 7.5 3.6 7.7 7.5 1.6 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal zf_ZIC PF18366.1 CBY38886.1 - 7 6.9 5.8 2.6 8.2 0.2 2.9 4 0 0 4 4 4 0 Zic proteins zinc finger domain La PF05383.17 CBY38887.1 - 2.6e-16 59.4 0.6 4.3e-16 58.7 0.6 1.4 1 0 0 1 1 1 1 La domain UPF0052 PF01933.18 CBY38887.1 - 0.051 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 RRM_1 PF00076.22 CBY38887.1 - 0.099 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypsin PF00089.26 CBY38888.1 - 1.6e-51 175.3 0.2 1.8e-51 175.1 0.2 1.0 1 0 0 1 1 1 1 Trypsin O-FucT PF10250.9 CBY38889.1 - 0.0012 18.6 0.0 0.0036 17.0 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPR_2 PF07719.17 CBY38890.1 - 5.6e-14 51.0 7.6 0.069 13.3 0.1 6.3 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBY38890.1 - 3.8e-13 48.6 6.8 0.0058 16.4 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBY38890.1 - 1.3e-10 40.9 0.1 0.32 11.5 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY38890.1 - 2.3e-10 40.8 2.1 0.00059 20.3 0.0 4.5 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY38890.1 - 4e-09 36.6 6.2 0.00098 19.3 0.1 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBY38890.1 - 5.9e-08 33.2 0.0 0.0028 18.3 0.0 3.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY38890.1 - 6.5e-08 32.8 3.4 0.065 13.5 1.3 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY38890.1 - 9.9e-08 31.6 13.9 0.12 12.6 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY38890.1 - 4.4e-06 27.1 0.1 2.5 9.2 0.0 4.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBY38890.1 - 6.1e-05 22.8 3.6 2.2 8.5 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBY38890.1 - 0.00061 19.4 2.5 1.4 8.7 0.0 4.9 3 1 1 4 4 4 2 TPR repeat Fis1_TPR_C PF14853.6 CBY38890.1 - 0.0019 18.2 3.1 0.81 9.8 0.1 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 CBY38890.1 - 0.045 13.5 2.2 0.099 12.4 0.2 2.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.6 CBY38890.1 - 1.5 9.6 5.4 2.1e+02 2.9 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 CBY38891.1 - 4.4e-62 209.8 0.0 3.5e-38 131.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38891.1 - 5.5e-40 137.3 0.0 3.5e-27 95.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY38891.1 - 2.5e-05 23.8 0.0 0.0086 15.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBY38891.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM91_C PF14648.6 CBY38891.1 - 0.0034 16.3 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 FAM91 C-terminus Pkinase_fungal PF17667.1 CBY38891.1 - 0.017 13.9 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBY38891.1 - 0.021 14.8 0.0 0.067 13.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBY38891.1 - 0.18 11.4 0.1 5.7 6.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2046 PF09755.9 CBY38892.1 - 2.3e-135 450.7 52.9 2.9e-135 450.4 52.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) WD40_alt PF14077.6 CBY38892.1 - 0.026 14.4 3.1 1.6 8.7 0.1 3.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 CBY38892.1 - 0.33 11.2 37.5 1.1 9.5 11.1 4.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BicD PF09730.9 CBY38892.1 - 3.1 6.1 49.4 0.5 8.7 24.2 2.1 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D ATG16 PF08614.11 CBY38892.1 - 3.7 7.7 57.1 1.1 9.5 17.3 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CBY38892.1 - 5.7 7.0 64.8 17 5.4 14.3 4.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Piwi PF02171.17 CBY38893.1 - 1.7e-110 369.0 0.0 3.2e-110 368.1 0.0 1.5 2 0 0 2 2 2 1 Piwi domain ArgoMid PF16487.5 CBY38893.1 - 2.5e-30 104.5 0.2 1.1e-29 102.5 0.2 2.2 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 CBY38893.1 - 7.8e-28 97.8 0.0 1.9e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CBY38893.1 - 7.3e-23 80.9 0.1 1.3e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 CBY38893.1 - 4.2e-22 77.6 0.2 9.4e-22 76.4 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY38893.1 - 5.3e-17 61.9 0.1 1.2e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF2475 PF10629.9 CBY38895.1 - 2.2e-19 69.4 3.9 2.7e-05 24.3 0.1 4.4 3 1 1 4 4 4 4 Protein of unknown function (DUF2475) SEA PF01390.20 CBY38896.1 - 0.0089 16.1 3.2 0.021 14.9 3.2 1.6 1 1 0 1 1 1 1 SEA domain MRP-L27 PF09809.9 CBY38896.1 - 0.15 11.9 0.6 0.52 10.1 0.1 2.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L27 SEA PF01390.20 CBY38897.1 - 0.0061 16.6 2.1 0.018 15.1 2.1 1.7 1 1 0 1 1 1 1 SEA domain CAS_CSE1 PF03378.15 CBY38897.1 - 0.05 12.1 1.2 0.06 11.8 1.2 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Secretin_N_2 PF07655.13 CBY38897.1 - 0.46 11.1 4.2 7.4 7.2 0.3 3.1 1 1 1 2 2 2 0 Secretin N-terminal domain SEA PF01390.20 CBY38898.1 - 0.068 13.3 1.5 0.14 12.2 1.5 1.7 1 1 0 1 1 1 0 SEA domain DUF3357 PF11837.8 CBY38900.1 - 0.012 16.1 0.2 0.012 16.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TSP_1 PF00090.19 CBY38901.1 - 5.7e-08 32.8 8.8 5.7e-08 32.8 8.8 3.4 2 1 1 3 3 3 2 Thrombospondin type 1 domain zf-RING_5 PF14634.6 CBY38902.1 - 1.6e-08 34.4 11.8 1.6e-08 34.4 11.8 2.8 3 2 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY38902.1 - 3.2e-06 27.4 12.6 3.2e-06 27.4 12.6 3.2 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY38902.1 - 0.00027 20.7 9.3 0.00027 20.7 9.3 3.1 4 1 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY38902.1 - 0.00073 19.5 5.0 0.00073 19.5 5.0 3.6 4 1 0 4 4 4 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY38902.1 - 0.0044 16.8 12.8 0.0044 16.8 12.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY38902.1 - 0.0046 16.8 11.6 0.0046 16.8 11.6 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CBY38902.1 - 0.012 15.4 11.7 0.012 15.4 11.7 3.1 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain DUF2256 PF10013.9 CBY38902.1 - 0.017 15.3 0.1 0.017 15.3 0.1 3.4 4 0 0 4 4 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FapA PF03961.13 CBY38902.1 - 0.042 12.5 1.3 0.05 12.2 1.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4398 PF14346.6 CBY38902.1 - 0.063 13.9 0.7 0.096 13.3 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) EspA PF03433.13 CBY38902.1 - 0.081 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 EspA-like secreted protein Rootletin PF15035.6 CBY38902.1 - 1 9.4 7.5 0.18 11.8 2.7 1.9 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion zf-RING_11 PF17123.5 CBY38902.1 - 1.3 8.8 8.6 1.1 9.0 1.6 3.3 3 1 0 3 3 3 0 RING-like zinc finger V-SNARE_C PF12352.8 CBY38903.1 - 1.7e-11 44.3 1.1 2.2e-11 43.9 1.1 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBY38903.1 - 8.2e-05 22.4 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Sec20 Shufflon_N PF04917.12 CBY38903.1 - 0.018 14.5 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region DUF5089 PF17002.5 CBY38903.1 - 0.033 14.1 0.1 0.041 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) DUF935 PF06074.12 CBY38904.1 - 0.067 11.9 5.0 0.077 11.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Kinesin PF00225.23 CBY38905.1 - 1.8e-41 142.2 0.0 5.5e-41 140.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CBY38905.1 - 1.2e-15 58.1 19.1 2.9e-11 43.9 0.6 4.4 3 2 1 4 4 4 2 Kinesin-associated FHA PF00498.26 CBY38905.1 - 7.9e-05 22.9 0.0 0.0004 20.7 0.0 2.3 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY38905.1 - 0.00058 20.1 0.0 0.0033 17.7 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Nuc_deoxyri_tr3 PF11071.8 CBY38905.1 - 0.42 10.7 2.8 0.83 9.7 0.2 2.8 3 0 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase YtoQ DUF4363 PF14276.6 CBY38905.1 - 3.7 7.7 9.4 0.32 11.1 0.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) Connexin PF00029.19 CBY38908.1 - 1.4e-39 136.2 2.0 1.8e-38 132.7 2.0 2.0 1 1 0 1 1 1 1 Connexin SecD-TM1 PF13721.6 CBY38908.1 - 0.0091 16.4 0.4 0.036 14.5 0.1 2.1 2 0 0 2 2 2 1 SecD export protein N-terminal TM region DUF2681 PF10883.8 CBY38908.1 - 0.045 14.2 5.1 0.063 13.7 3.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) Kelch_2 PF07646.15 CBY38909.1 - 3.9e-05 23.4 4.3 0.18 11.8 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY38909.1 - 0.023 15.0 4.6 1.4 9.3 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DUF3326 PF11805.8 CBY38909.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Kelch_4 PF13418.6 CBY38909.1 - 0.13 12.3 2.9 11 6.1 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY38909.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.4 3 0 0 3 3 3 0 Kelch motif PSS PF03034.15 CBY38910.1 - 8.4e-101 337.3 20.5 1.2e-100 336.8 20.5 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase LapA_dom PF06305.11 CBY38910.1 - 0.039 13.8 1.8 0.68 9.8 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1129 PF06570.11 CBY38910.1 - 0.35 10.3 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Hydrolase_6 PF13344.6 CBY38911.1 - 7.4e-17 61.3 0.0 3.9e-14 52.6 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CBY38911.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HXXSHH PF07586.11 CBY38914.1 - 0.12 11.9 2.0 0.26 10.8 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) zf-C4 PF00105.18 CBY38916.1 - 1.1e-11 45.0 11.1 3e-11 43.6 11.1 1.8 1 1 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY38916.1 - 4.5 7.7 7.3 2.6 8.4 1.1 2.5 2 0 0 2 2 2 0 C1 domain Astacin PF01400.24 CBY38918.1 - 8.7e-20 71.1 0.0 8.2e-18 64.7 0.0 2.3 1 1 1 2 2 2 2 Astacin (Peptidase family M12A) DUF5622 PF18533.1 CBY38918.1 - 0.23 11.6 0.0 0.48 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) Pkinase PF00069.25 CBY38919.1 - 2.2e-64 217.4 0.0 3.6e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38919.1 - 1.3e-33 116.4 0.0 1.9e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1908 PF08926.11 CBY38919.1 - 2e-24 86.2 0.1 2e-24 86.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) APH PF01636.23 CBY38919.1 - 8.4e-06 25.9 0.0 0.039 13.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY38919.1 - 8.9e-06 25.2 0.3 0.00054 19.4 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY38919.1 - 0.00011 21.6 0.7 0.00021 20.7 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBY38919.1 - 0.0002 20.4 0.2 0.00093 18.2 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY38919.1 - 0.0052 16.4 0.4 0.017 14.7 0.3 1.9 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CBY38919.1 - 0.0065 16.1 0.1 0.076 12.6 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 CBY38919.1 - 0.21 12.3 1.0 0.77 10.5 0.6 2.3 2 0 0 2 2 2 0 Protein kinase C terminal domain EF-hand_1 PF00036.32 CBY38920.1 - 8.4e-10 37.5 6.7 0.00015 21.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY38920.1 - 1.6e-08 33.8 6.1 6.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBY38920.1 - 8.3e-08 32.6 5.0 1.1e-07 32.1 4.7 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY38920.1 - 0.011 15.6 2.8 0.011 15.6 2.8 1.8 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CBY38920.1 - 0.069 12.7 6.3 1.3 8.7 0.3 2.4 2 0 0 2 2 2 0 EF hand Collagen PF01391.18 CBY38921.1 - 6.9e-50 166.7 196.4 4.1e-09 36.1 29.2 7.2 1 1 5 6 6 6 6 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY38921.1 - 6.4e-29 101.4 0.1 2.1e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CBY38921.1 - 1.4e-12 48.2 0.4 7.6e-06 26.5 0.0 2.7 3 0 0 3 3 3 2 von Willebrand factor type A domain Copine PF07002.16 CBY38921.1 - 5.5e-05 22.7 0.1 0.0021 17.5 0.1 2.1 2 0 0 2 2 2 1 Copine CobN-Mg_chel PF02514.16 CBY38921.1 - 0.0007 17.5 0.0 0.00097 17.0 0.0 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase CobT_C PF11775.8 CBY38921.1 - 0.2 11.3 0.0 2.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain PTEN_C2 PF10409.9 CBY38922.1 - 2.4e-21 75.9 0.1 3.6e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CBY38922.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY38922.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY38922.1 - 0.054 13.5 0.1 0.086 12.8 0.1 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family FH2 PF02181.23 CBY38923.1 - 1.1e-13 51.1 0.5 1.4e-13 50.7 0.5 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain MRP-S27 PF10037.9 CBY38923.1 - 0.034 13.0 3.2 0.043 12.7 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 EF-hand_7 PF13499.6 CBY38924.1 - 3e-15 56.4 0.6 1.8e-06 28.3 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY38924.1 - 4.6e-15 54.0 2.7 3.6e-06 26.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY38924.1 - 1.4e-13 49.6 1.1 2.5e-05 23.8 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY38924.1 - 5.9e-11 41.3 3.9 9.6e-05 21.7 1.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY38924.1 - 1.7e-10 40.6 0.3 7.4e-06 25.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 CBY38924.1 - 0.0014 18.6 0.6 0.051 13.5 0.0 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Kelch_2 PF07646.15 CBY38924.1 - 0.0018 18.2 4.1 1.6 8.8 0.0 3.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CBY38924.1 - 0.0058 16.6 1.2 0.16 12.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif SPARC_Ca_bdg PF10591.9 CBY38924.1 - 0.019 15.3 0.4 0.48 10.8 0.4 2.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Zap1_zf2 PF18217.1 CBY38924.1 - 0.059 13.4 0.5 0.059 13.4 0.5 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 Kelch_6 PF13964.6 CBY38924.1 - 0.062 13.6 1.1 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif FOXP-CC PF16159.5 CBY38924.1 - 0.076 13.6 2.8 0.14 12.8 0.1 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain NTP_transf_9 PF04248.12 CBY38924.1 - 0.086 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Mod_r PF07200.13 CBY38926.1 - 1.3e-33 116.2 9.7 1.4e-33 116.0 9.7 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 CBY38926.1 - 0.012 14.6 7.0 0.014 14.3 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4422 PF14393.6 CBY38926.1 - 0.1 12.4 0.3 0.13 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Atg14 PF10186.9 CBY38926.1 - 0.34 9.9 5.6 0.4 9.7 5.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 CBY38926.1 - 0.39 11.4 2.5 0.69 10.7 2.5 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) UPF0449 PF15136.6 CBY38926.1 - 0.99 9.9 5.2 4 8.0 5.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 TMF_DNA_bd PF12329.8 CBY38926.1 - 7 6.7 14.1 2.7 8.1 1.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tam41_Mmp37 PF09139.11 CBY38927.1 - 8.9e-49 166.7 0.0 1.5e-48 166.0 0.0 1.3 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial EXOSC1 PF10447.9 CBY38928.1 - 2.1e-14 54.1 1.6 6.3e-10 39.6 0.2 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CBY38928.1 - 4.6e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CS PF04969.16 CBY38929.1 - 6.3e-14 52.7 0.1 2.2e-13 51.0 0.1 2.0 1 0 0 1 1 1 1 CS domain VASt PF16016.5 CBY38930.1 - 1.7e-26 93.5 0.9 3.3e-26 92.5 0.9 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CBY38930.1 - 1.9e-24 85.7 0.7 3.8e-24 84.8 0.7 1.4 1 0 0 1 1 1 1 GRAM domain RNase_T PF00929.24 CBY38931.1 - 2.1e-26 93.4 0.0 2.4e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Thioredoxin PF00085.20 CBY38932.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin adh_short PF00106.25 CBY38933.1 - 1.7e-23 83.1 0.0 2.9e-19 69.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBY38933.1 - 2.9e-14 53.2 0.0 1.4e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY38933.1 - 0.0011 19.0 0.1 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 KR domain CD225 PF04505.12 CBY38934.1 - 2.2e-13 50.1 0.5 3.8e-13 49.4 0.5 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Kelch_6 PF13964.6 CBY38936.1 - 5.9e-24 83.5 0.0 4.6e-07 29.9 0.0 4.7 1 1 3 4 4 4 4 Kelch motif Kelch_1 PF01344.25 CBY38936.1 - 1.4e-23 82.2 0.1 7.6e-08 31.8 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CBY38936.1 - 2.9e-15 56.0 0.0 1.4e-05 25.0 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY38936.1 - 1e-14 54.4 0.0 0.00011 22.4 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY38936.1 - 1.4e-12 47.3 0.0 0.00083 19.3 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY38936.1 - 1.8e-07 30.8 0.0 0.65 10.1 0.0 4.8 4 1 0 4 4 4 2 Kelch motif BTB PF00651.31 CBY38936.1 - 1.3e-06 28.6 0.5 2.8e-06 27.5 0.5 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY38936.1 - 8.6e-06 25.8 0.1 1.9e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Integrin_alpha2 PF08441.12 CBY38938.1 - 3.9e-36 124.9 0.4 4.9e-36 124.6 0.4 1.0 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY38938.1 - 7e-05 22.9 0.3 0.00015 21.8 0.3 1.5 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 CBY38938.1 - 0.026 15.1 0.0 0.068 13.8 0.0 1.8 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella OxoGdeHyase_C PF16870.5 CBY38939.1 - 4.3e-43 146.6 0.0 8.3e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 CBY38939.1 - 3.8e-40 137.5 0.0 7.7e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Pkinase PF00069.25 CBY38939.1 - 3.4e-24 85.6 0.0 4.9e-23 81.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38939.1 - 2.3e-13 50.0 0.0 4e-11 42.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY38939.1 - 0.0036 17.3 0.2 0.0068 16.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PFOR_II PF17147.4 CBY38939.1 - 0.044 14.1 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Pox_ser-thr_kin PF05445.11 CBY38939.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBY38939.1 - 0.15 10.8 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase WH2 PF02205.20 CBY38940.1 - 9.9e-07 28.4 0.1 1.7e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 WH2 motif APP_N PF02177.16 CBY38940.1 - 9.8e-06 25.9 0.2 1.5e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding DUF4996 PF16387.5 CBY38940.1 - 0.029 14.8 0.0 0.075 13.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function IRK_C PF17655.1 CBY38942.1 - 7.4e-65 217.8 0.1 1.1e-64 217.2 0.1 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 CBY38942.1 - 4.1e-54 182.2 2.6 8.2e-54 181.3 2.6 1.5 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain KCH PF16944.5 CBY38942.1 - 2.2 8.0 7.0 3 7.5 3.4 2.5 3 0 0 3 3 3 0 Fungal potassium channel Ion_trans_2 PF07885.16 CBY38942.1 - 4.5 7.3 12.8 0.12 12.3 1.4 2.3 2 0 0 2 2 2 0 Ion channel DUF3502 PF12010.8 CBY38943.1 - 0.011 16.4 2.9 2.4 8.8 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) DUF3909 PF13077.6 CBY38943.1 - 0.043 14.0 0.7 0.082 13.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF2703 PF10865.8 CBY38943.1 - 0.06 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) ABC_tran PF00005.27 CBY38944.1 - 8.4e-24 84.6 0.0 2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY38944.1 - 9.6e-13 48.6 1.9 3.8e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CBY38944.1 - 2.4e-09 36.8 12.6 5.9e-09 35.5 12.6 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CBY38944.1 - 1.7e-05 24.8 0.1 3.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBY38944.1 - 0.00025 20.7 0.1 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY38944.1 - 0.00045 20.0 5.2 0.013 15.3 4.5 3.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CBY38944.1 - 0.00062 19.3 0.2 0.59 9.5 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY38944.1 - 0.0023 18.3 0.0 0.099 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CBY38944.1 - 0.01 16.4 11.3 0.02 15.4 7.5 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBY38944.1 - 0.089 12.9 0.3 0.27 11.3 0.2 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fib_alpha PF08702.10 CBY38945.1 - 0.0033 17.6 0.0 0.0041 17.3 0.0 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family ERAP1_C PF11838.8 CBY38947.1 - 5.2e-21 75.5 1.0 6.8e-21 75.1 1.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CBY38948.1 - 2e-53 181.2 0.1 2.5e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M1 domain L51_S25_CI-B8 PF05047.16 CBY38948.1 - 0.027 14.4 1.0 10 6.1 0.0 3.0 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain WLM PF08325.10 CBY38948.1 - 0.054 13.6 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 WLM domain Flavi_glycop_C PF02832.16 CBY38948.1 - 0.17 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Pkinase PF00069.25 CBY38949.1 - 3.7e-10 39.6 0.0 9.6e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY38949.1 - 5.4e-08 32.4 0.0 1.9e-07 30.6 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 CBY38950.1 - 4.6e-06 25.8 0.3 0.00053 19.3 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY38950.1 - 1.1e-05 24.7 0.8 3.1e-05 23.3 0.3 1.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY38950.1 - 3.8e-05 24.1 0.0 5.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY38950.1 - 0.00029 20.5 0.2 0.039 13.9 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBY38950.1 - 0.16 11.9 0.2 0.61 10.0 0.2 1.7 1 1 1 2 2 2 0 EF-hand domain pair LRR_8 PF13855.6 CBY38951.1 - 7.3e-32 108.9 34.0 3.1e-12 46.0 0.3 6.2 2 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 CBY38951.1 - 4.5e-26 90.5 28.0 8.7e-05 22.8 4.2 6.2 2 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRRNT PF01462.18 CBY38951.1 - 1.5e-09 37.3 1.5 2.8e-08 33.2 1.2 2.7 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 CBY38951.1 - 8e-07 28.8 29.4 1.3 9.8 0.1 8.7 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 CBY38951.1 - 4e-06 26.5 9.4 0.86 9.1 0.0 3.8 1 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBY38951.1 - 0.00025 20.9 26.7 1.6 8.9 1.2 7.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_2 PF07723.13 CBY38951.1 - 0.0015 19.1 10.9 0.13 13.0 0.1 6.3 5 3 2 7 7 7 1 Leucine Rich Repeat LRR_5 PF13306.6 CBY38951.1 - 0.0017 18.3 0.0 0.42 10.6 0.0 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 CBY38951.1 - 0.026 14.7 0.4 0.026 14.7 0.4 3.6 4 0 0 4 4 4 0 FNIP Repeat DUF3557 PF12078.8 CBY38951.1 - 0.39 10.6 4.6 4.8 7.1 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3557) NYN PF01936.18 CBY38952.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 NYN domain Pou PF00157.17 CBY38954.1 - 3.5e-31 107.0 0.0 7.6e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY38954.1 - 5.2e-17 61.4 2.0 1.1e-16 60.3 2.0 1.6 1 0 0 1 1 1 1 Homeodomain HTH_31 PF13560.6 CBY38954.1 - 1.5e-05 25.2 0.1 0.00093 19.5 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 CBY38954.1 - 0.096 12.8 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Homeobox_KN PF05920.11 CBY38954.1 - 0.13 12.1 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF4770 PF15994.5 CBY38954.1 - 0.14 12.4 2.1 0.24 11.6 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) I-set PF07679.16 CBY38955.1 - 4.1e-180 584.4 74.7 7.4e-17 61.2 0.1 25.3 25 0 0 25 25 25 22 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY38955.1 - 3.4e-114 373.6 11.3 5.9e-08 33.2 0.0 23.8 24 0 0 24 24 24 17 Immunoglobulin domain fn3 PF00041.21 CBY38955.1 - 2.6e-68 226.4 0.0 6.6e-12 45.6 0.0 7.6 7 0 0 7 7 7 6 Fibronectin type III domain ig PF00047.25 CBY38955.1 - 1e-62 208.3 28.6 8.5e-07 29.1 0.5 17.3 18 0 0 18 18 17 11 Immunoglobulin domain Ig_2 PF13895.6 CBY38955.1 - 7.9e-51 170.3 12.0 0.00031 21.0 0.0 18.3 20 0 0 20 20 20 10 Immunoglobulin domain V-set PF07686.17 CBY38955.1 - 2.3e-29 101.7 18.7 0.00095 19.3 0.0 16.4 16 2 0 16 16 15 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY38955.1 - 2.3e-11 43.6 18.3 2.1 8.4 0.1 12.6 15 0 0 15 15 14 3 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY38955.1 - 3.6e-11 43.0 6.2 0.29 11.2 0.0 10.5 11 1 0 11 11 11 2 CD80-like C2-set immunoglobulin domain BiPBP_C PF06832.12 CBY38955.1 - 6.9e-11 42.0 0.2 0.43 10.6 0.0 10.3 11 0 0 11 11 10 1 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 CBY38955.1 - 2.7e-07 30.7 21.5 0.17 12.2 0.1 11.1 14 0 0 14 14 12 2 T-cell surface glycoprotein CD3 delta chain Receptor_2B4 PF11465.8 CBY38955.1 - 8.5e-06 25.9 5.8 2 8.7 0.0 9.1 10 0 0 10 10 10 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 CBY38955.1 - 1.9e-05 24.2 0.0 0.39 10.3 0.0 5.5 6 0 0 6 6 6 1 Immunoglobulin domain Ig_5 PF16681.5 CBY38955.1 - 3.3e-05 24.2 24.0 0.16 12.4 0.0 10.6 13 0 0 13 13 10 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Herpes_gE PF02480.16 CBY38955.1 - 0.00022 20.1 3.3 0.41 9.3 0.1 5.4 4 2 0 4 4 4 1 Alphaherpesvirus glycoprotein E C1-set PF07654.15 CBY38955.1 - 0.00041 20.7 18.0 0.89 10.0 0.0 9.6 12 0 0 12 12 9 2 Immunoglobulin C1-set domain MBG_2 PF18676.1 CBY38955.1 - 0.006 17.2 6.3 49 4.7 0.1 6.6 7 0 0 7 7 6 0 MBG domain (YGX type) SusE PF14292.6 CBY38955.1 - 0.0077 16.4 11.5 0.33 11.2 0.1 6.7 7 0 0 7 7 6 1 SusE outer membrane protein C2-set PF05790.15 CBY38955.1 - 0.12 12.6 12.5 55 4.0 0.1 8.1 10 0 0 10 10 8 0 Immunoglobulin C2-set domain CBM_4_9 PF02018.17 CBY38955.1 - 0.85 9.9 6.7 14 6.0 0.1 5.2 5 0 0 5 5 3 0 Carbohydrate binding domain DUF2914 PF11141.8 CBY38955.1 - 3.1 7.6 10.7 4.1 7.2 0.1 6.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2914) tRNA-synt_2c PF01411.19 CBY38956.1 - 1.2e-208 694.1 0.0 2e-208 693.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBY38956.1 - 1e-11 44.8 1.1 1.4e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CBY38956.1 - 1e-09 38.9 1.6 1e-09 38.9 1.6 2.9 2 1 1 3 3 3 1 DHHA1 domain CD36 PF01130.21 CBY38957.1 - 7.7e-98 328.0 0.0 1e-97 327.6 0.0 1.2 1 0 0 1 1 1 1 CD36 family DUF525 PF04379.14 CBY38959.1 - 0.00061 20.0 0.0 0.001 19.3 0.0 1.4 1 1 0 1 1 1 1 ApaG domain YccV-like PF08755.11 CBY38960.1 - 0.0012 19.3 0.0 0.0035 17.8 0.0 1.8 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like zf-SNAP50_C PF12251.8 CBY38961.1 - 7.2e-63 211.9 4.6 1e-62 211.4 4.6 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal MIF PF01187.18 CBY38962.1 - 2.2e-28 98.8 0.0 2.5e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF2723 PF11028.8 CBY38964.1 - 0.72 9.8 10.2 0.53 10.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2723) Cyclin_N PF00134.23 CBY38965.1 - 1.3e-13 50.8 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CBY38965.1 - 1e-12 48.7 0.1 1.5e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin Lectin_C PF00059.21 CBY38966.1 - 5.2e-08 33.6 0.7 1.2e-07 32.4 0.7 1.7 1 0 0 1 1 1 1 Lectin C-type domain Tubulin PF00091.25 CBY38966.1 - 0.058 13.6 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain Atg8 PF02991.16 CBY38967.1 - 2.1e-27 95.3 0.0 2.5e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBY38967.1 - 2.6e-07 31.0 0.0 3.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Tetraspanin PF00335.20 CBY38968.1 - 1.2e-51 175.7 8.5 1.3e-51 175.5 8.5 1.0 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_2 PF12679.7 CBY38968.1 - 1.3 8.2 6.2 0.16 11.2 2.1 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein CUB PF00431.20 CBY38969.1 - 1.8e-05 25.0 0.3 3.4e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 CUB domain AP3D1 PF06375.11 CBY38969.1 - 0.83 9.9 9.7 1.5 9.1 9.7 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Trypsin PF00089.26 CBY38970.1 - 1.8e-73 247.0 8.9 3.2e-42 144.8 0.0 4.4 5 0 0 5 5 5 3 Trypsin Trypsin_2 PF13365.6 CBY38970.1 - 1.8e-06 28.9 0.0 0.016 16.1 0.0 3.0 2 1 0 2 2 2 2 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY38970.1 - 0.00078 19.8 2.1 2.1 8.8 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY38970.1 - 1.3 9.0 64.8 2.5 8.1 64.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 CBY38970.1 - 9.1 6.7 27.1 22 5.5 27.1 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SET PF00856.28 CBY38972.1 - 6.7e-06 26.6 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 SET domain ANF_receptor PF01094.28 CBY38973.1 - 0.043 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region COPI_C PF06957.11 CBY38975.1 - 4.6e-92 308.9 0.5 5.6e-92 308.6 0.5 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TPR_2 PF07719.17 CBY38975.1 - 0.14 12.3 0.0 27 5.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 CBY38976.1 - 7.4e-14 52.0 0.1 8.9e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY38976.1 - 5.5e-11 42.5 0.2 7.3e-11 42.1 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY38976.1 - 1.3e-09 38.3 0.1 2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY38976.1 - 0.00021 21.5 0.1 0.00026 21.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY38976.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CBY38976.1 - 0.042 14.0 0.1 0.1 12.8 0.1 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase zf-RING_2 PF13639.6 CBY38977.1 - 1.1e-05 25.6 19.4 1.1e-05 25.6 19.4 2.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CBY38977.1 - 6.2e-05 22.9 20.4 6.2e-05 22.9 20.4 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY38977.1 - 0.0011 18.8 17.2 0.0011 18.8 17.2 3.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBY38977.1 - 0.0061 15.9 6.2 0.0094 15.3 6.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CBY38977.1 - 0.0099 15.7 17.0 0.0099 15.7 17.0 3.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY38977.1 - 0.12 12.4 20.6 0.058 13.4 14.8 2.8 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY38977.1 - 3.5 7.5 28.3 0.12 12.2 18.8 3.1 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY38977.1 - 3.8 7.4 20.5 0.32 10.8 14.7 2.4 2 0 0 2 2 2 0 RING-like zinc finger PolC_DP2 PF03833.13 CBY38977.1 - 4.3 5.1 4.6 5.1 4.8 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Host_attach PF10116.9 CBY38978.1 - 0.031 14.9 0.4 0.031 14.9 0.4 1.9 2 1 0 2 2 2 0 Protein required for attachment to host cells COPI_C PF06957.11 CBY38980.1 - 3.1e-165 549.8 0.0 3.5e-165 549.7 0.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TPR_14 PF13428.6 CBY38980.1 - 0.17 12.8 0.2 63 4.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ammonium_transp PF00909.21 CBY38981.1 - 2e-83 280.3 16.7 2.4e-83 280.1 16.7 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family cEGF PF12662.7 CBY38984.1 - 1.3e-10 41.0 13.8 8.3e-07 28.8 1.5 4.2 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY38984.1 - 1.9e-08 34.4 21.5 1.1e-07 32.0 7.5 5.9 4 1 1 5 5 5 2 Calcium-binding EGF domain TSP_1 PF00090.19 CBY38984.1 - 3e-08 33.8 24.2 6.3e-08 32.7 7.6 4.9 5 0 0 5 5 5 3 Thrombospondin type 1 domain EGF_3 PF12947.7 CBY38984.1 - 8.3e-07 29.1 33.3 0.00018 21.6 2.5 4.4 3 0 0 3 3 3 3 EGF domain hEGF PF12661.7 CBY38984.1 - 4.2e-05 24.0 29.3 0.013 16.2 3.6 5.4 4 0 0 4 4 4 3 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY38984.1 - 0.00066 19.7 2.7 0.00066 19.7 2.7 5.8 7 0 0 7 7 7 3 MSP1 EGF domain 1 EGF PF00008.27 CBY38984.1 - 0.0014 18.9 44.4 0.05 13.9 4.8 5.5 5 0 0 5 5 5 3 EGF-like domain FXa_inhibition PF14670.6 CBY38984.1 - 0.002 18.3 2.7 0.002 18.3 2.7 5.3 3 1 2 5 5 5 2 Coagulation Factor Xa inhibitory site Forkhead PF00250.18 CBY38985.1 - 1.5e-21 76.4 0.5 1.5e-21 76.4 0.5 1.6 2 0 0 2 2 2 1 Forkhead domain Trypsin PF00089.26 CBY38987.1 - 1.5e-61 208.0 0.1 3e-61 207.0 0.0 1.6 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY38987.1 - 9.8e-29 99.9 0.5 9.1e-14 51.7 0.1 2.5 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 CBY38987.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Glycos_transf_2 PF00535.26 CBY38988.1 - 5.4e-11 42.6 0.2 1.7e-10 41.0 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 EF-hand_6 PF13405.6 CBY38989.1 - 5.2e-09 35.3 0.4 1.4e-08 34.0 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY38989.1 - 2.4e-07 29.8 0.1 5.3e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY38989.1 - 3.2e-07 30.7 0.0 4.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CBY38989.1 - 1.2e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CBY38989.1 - 3.9e-06 26.1 0.3 8.4e-06 25.1 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY38989.1 - 5.9e-06 26.0 0.6 0.0011 18.7 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_14 PF17959.1 CBY38989.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain FGAR-AT_linker PF18072.1 CBY38989.1 - 0.042 14.4 0.0 0.062 13.9 0.0 1.5 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain Amino_oxidase PF01593.24 CBY38991.1 - 2e-60 205.4 0.0 2.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Tudor_3 PF18115.1 CBY38991.1 - 0.078 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Cullin PF00888.22 CBY38992.1 - 5.7e-55 187.1 18.0 6.8e-55 186.8 18.0 1.0 1 0 0 1 1 1 1 Cullin family Xpo1 PF08389.12 CBY38992.1 - 0.22 11.6 2.7 0.24 11.4 0.5 2.2 2 1 1 3 3 3 0 Exportin 1-like protein OSCP PF00213.18 CBY38992.1 - 0.31 11.1 3.8 0.9 9.6 0.1 2.8 2 2 2 4 4 4 0 ATP synthase delta (OSCP) subunit AbiH PF14253.6 CBY38992.1 - 3.1 7.6 16.9 5.7 6.7 4.7 2.7 2 1 0 2 2 2 0 Bacteriophage abortive infection AbiH Cullin PF00888.22 CBY38993.1 - 1.5e-41 142.7 1.6 1.5e-41 142.7 1.6 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CBY38993.1 - 1.2e-15 57.2 0.1 4.2e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain 7TM_GPCR_Srj PF10319.9 CBY38993.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj Lipocalin_8 PF16585.5 CBY38993.1 - 1.5 9.3 5.1 0.95 9.9 0.8 2.4 2 1 1 3 3 3 0 Lipocalin-like domain AA_permease_2 PF13520.6 CBY38994.1 - 2.3e-55 188.2 46.2 2.6e-55 188.0 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY38994.1 - 2.6e-22 79.1 36.9 3.4e-22 78.7 36.9 1.2 1 0 0 1 1 1 1 Amino acid permease MAPEG PF01124.18 CBY38995.1 - 1.9e-12 47.2 0.2 2.2e-11 43.8 0.2 2.0 1 1 0 1 1 1 1 MAPEG family HHH_5 PF14520.6 CBY38996.1 - 8.3e-07 29.5 0.1 1.3e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 CBY38996.1 - 0.009 16.2 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Pathogenicity locus Abi_C PF14355.6 CBY38996.1 - 0.036 14.2 0.1 0.054 13.6 0.1 1.3 1 0 0 1 1 1 0 Abortive infection C-terminus DUF3772 PF12607.8 CBY38996.1 - 0.059 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) HHH_3 PF12836.7 CBY38996.1 - 0.12 12.7 0.3 0.59 10.4 0.1 2.1 2 1 1 3 3 3 0 Helix-hairpin-helix motif Helicase_C PF00271.31 CBY38997.1 - 5.5e-12 46.0 0.0 1.6e-10 41.3 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY38997.1 - 7.2e-11 42.2 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med26 PF08711.11 CBY38998.1 - 6.7e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain AAA_assoc_C PF09821.9 CBY38998.1 - 0.11 13.0 0.3 0.3 11.6 0.3 1.7 1 0 0 1 1 1 0 C-terminal AAA-associated domain zf-DNL PF05180.12 CBY38999.1 - 3e-30 104.0 0.9 3.9e-30 103.6 0.9 1.2 1 0 0 1 1 1 1 DNL zinc finger PADR1 PF08063.12 CBY38999.1 - 0.073 12.9 0.1 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain Myosin_head PF00063.21 CBY39000.1 - 9.9e-189 628.8 0.1 1.2e-188 628.5 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Cellulase PF00150.18 CBY39000.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AAA_22 PF13401.6 CBY39000.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 CBY39000.1 - 0.034 13.7 0.8 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Microtub_bd PF16796.5 CBY39000.1 - 0.035 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Microtubule binding Sigma54_activat PF00158.26 CBY39000.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBY39000.1 - 0.059 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CBY39000.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain OTU PF02338.19 CBY39000.1 - 0.13 12.8 0.1 0.83 10.2 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease DUF4231 PF14015.6 CBY39002.1 - 0.015 15.7 0.3 0.023 15.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Tau95_N PF17682.1 CBY39002.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 Tau95 Triple barrel domain Spore_permease PF03845.13 CBY39002.1 - 0.075 11.9 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Spore germination protein zf-RING_5 PF14634.6 CBY39003.1 - 1.7e-05 24.6 7.8 1.7e-05 24.6 7.8 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY39003.1 - 4.1e-05 23.3 7.2 9.1e-05 22.2 7.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBY39003.1 - 5.5e-05 22.9 9.4 6.8e-05 22.6 7.9 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY39003.1 - 6.8e-05 22.6 10.6 0.00012 21.8 8.2 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY39003.1 - 9.7e-05 22.6 8.4 0.00019 21.7 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CBY39003.1 - 0.00016 21.2 4.9 0.00017 21.1 4.4 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 CBY39003.1 - 0.0014 18.6 3.1 0.0016 18.4 2.2 1.5 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_UBOX PF13445.6 CBY39003.1 - 0.0084 16.1 4.3 0.038 14.0 2.7 2.5 2 1 1 3 3 3 1 RING-type zinc-finger DUF3391 PF11871.8 CBY39003.1 - 0.0088 16.6 0.3 0.011 16.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HisKA_3 PF07730.13 CBY39003.1 - 0.022 15.3 0.4 0.07 13.7 0.3 1.9 1 1 0 2 2 2 0 Histidine kinase zf-C3HC4_2 PF13923.6 CBY39003.1 - 0.047 13.5 9.1 0.13 12.1 9.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DnaB_2 PF07261.11 CBY39003.1 - 0.057 13.2 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment CHIP_TPR_N PF18391.1 CBY39003.1 - 0.15 12.8 5.7 0.31 11.8 5.7 1.7 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain DUF1090 PF06476.12 CBY39003.1 - 0.15 12.1 6.8 0.26 11.4 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) zf-C3HC4 PF00097.25 CBY39003.1 - 0.18 11.7 8.4 3.9 7.4 9.0 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF883 PF05957.13 CBY39003.1 - 0.18 12.4 2.2 0.31 11.7 1.7 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) IBR PF01485.21 CBY39003.1 - 0.22 11.8 8.6 1.7 8.9 8.6 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 CBY39003.1 - 0.49 10.2 0.2 0.49 10.2 0.2 3.2 2 1 0 2 2 1 0 zinc-ribbon domain zf-CHY PF05495.12 CBY39003.1 - 1.1 9.7 9.6 36 4.9 6.6 2.9 2 1 0 2 2 2 0 CHY zinc finger DUF1272 PF06906.11 CBY39003.1 - 1.9 8.6 9.1 0.74 9.9 6.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.6 CBY39003.1 - 3.5 7.6 13.5 8.6 6.4 5.5 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_10 PF16685.5 CBY39003.1 - 6.6 6.9 10.6 0.56 10.4 4.6 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Gly_rich PF12810.7 CBY39006.1 - 9.2e-08 32.3 59.0 3.4e-07 30.4 36.7 2.7 1 1 1 2 2 2 1 Glycine rich protein Lactamase_B PF00753.27 CBY39008.1 - 5.2e-06 26.6 6.1 5.4e-05 23.3 6.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY39008.1 - 0.023 14.2 1.2 0.056 12.9 0.7 1.9 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Bromo_TP PF07524.13 CBY39009.1 - 2.2e-06 27.6 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF4011 PF13195.6 CBY39009.1 - 8.3 6.3 7.3 58 3.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4011) CNH PF00780.22 CBY39012.1 - 8.1e-23 81.4 0.0 9.2e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 CNH domain Pkinase PF00069.25 CBY39013.1 - 1.5e-12 47.4 0.1 2.2e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39013.1 - 4.2e-10 39.4 0.0 9.4e-10 38.2 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CBY39015.1 - 7.5e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39015.1 - 4.7e-06 26.1 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TcA_RBD PF18518.1 CBY39015.1 - 0.064 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 TcA receptor binding domain Ald_Xan_dh_C2 PF02738.18 CBY39016.1 - 9.9e-172 572.2 0.0 1.4e-171 571.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY39016.1 - 4.8e-31 107.8 0.0 9.3e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CBY39016.1 - 8.2e-31 105.9 0.1 1.9e-30 104.7 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 CBY39016.1 - 7e-25 87.5 0.1 1.5e-24 86.5 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 CBY39016.1 - 5.7e-22 77.8 0.0 1.8e-21 76.2 0.0 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 CBY39016.1 - 6.3e-08 32.5 0.2 6.3e-08 32.5 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fib_alpha PF08702.10 CBY39017.1 - 5.8 7.1 9.4 2.2 8.4 0.5 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CIMR PF00878.18 CBY39018.1 - 3.9e-81 270.1 61.7 2.1e-17 63.5 2.8 11.5 9 4 1 10 10 10 9 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 CBY39018.1 - 4.5e-09 36.2 17.6 0.26 10.9 0.2 6.2 5 1 1 6 6 6 5 Glucosidase II beta subunit-like protein 14-3-3 PF00244.20 CBY39019.1 - 4.2e-107 356.7 2.6 4.8e-107 356.5 2.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Kelch_6 PF13964.6 CBY39020.1 - 0.00012 22.2 0.3 0.21 12.0 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY39020.1 - 0.002 18.1 4.9 0.38 10.8 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CBY39020.1 - 0.0026 17.3 5.1 1.6 8.4 0.0 3.6 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBY39020.1 - 0.0054 16.7 1.6 10 6.3 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CBY39020.1 - 0.021 14.8 2.4 0.16 12.0 0.0 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Requiem_N PF14051.6 CBY39022.1 - 1.1e-20 73.6 6.0 1.1e-20 73.6 6.0 1.6 2 0 0 2 2 2 1 N-terminal domain of DPF2/REQ. Hpr_kinase_N PF02603.16 CBY39023.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 HPr Serine kinase N terminus Astacin PF01400.24 CBY39025.1 - 5.7e-18 65.2 0.0 2.8e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 CBY39025.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CBY39025.1 - 0.12 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3677 PF12432.8 CBY39026.1 - 3.3e-11 43.4 0.4 7.1e-10 39.1 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) CSN8_PSD8_EIF3K PF10075.9 CBY39026.1 - 0.008 16.2 0.1 0.043 13.8 0.1 2.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family KIX_2 PF16987.5 CBY39026.1 - 0.041 13.9 0.0 0.21 11.6 0.0 2.3 1 0 0 1 1 1 0 KIX domain COG5 PF10392.9 CBY39026.1 - 1.5 9.0 8.4 9.4 6.4 0.0 3.6 4 0 0 4 4 4 0 Golgi transport complex subunit 5 zf-Tim10_DDP PF02953.15 CBY39027.1 - 2.9e-16 58.8 7.1 3.7e-16 58.5 7.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3213 PF11491.8 CBY39027.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3213) DUF2368 PF10166.9 CBY39028.1 - 1.8e-32 111.7 0.6 2e-32 111.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2368) IMPa_helical PF18642.1 CBY39029.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain RabGAP-TBC PF00566.18 CBY39030.1 - 6.6e-48 163.2 0.4 1.3e-47 162.3 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fer2 PF00111.27 CBY39031.1 - 3.3e-09 36.6 0.5 4.3e-09 36.2 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4749 PF15936.5 CBY39032.1 - 0.27 12.4 0.2 0.27 12.4 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4749) UDPGP PF01704.18 CBY39033.1 - 7.3e-75 252.1 0.0 9.1e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_fiss_Elm1 PF06258.11 CBY39033.1 - 0.063 12.4 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission ELM1 DUF1647 PF07801.11 CBY39033.1 - 0.098 12.4 0.6 0.32 10.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF4478 PF14793.6 CBY39033.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases UDPGP PF01704.18 CBY39034.1 - 1.7e-94 316.9 1.0 1.9e-94 316.7 1.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FG-GAP_2 PF14312.6 CBY39034.1 - 0.11 12.7 0.4 0.21 11.9 0.4 1.4 1 0 0 1 1 1 0 FG-GAP repeat GDC-P PF02347.16 CBY39035.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein ASD1 PF08688.10 CBY39035.1 - 0.093 13.1 6.8 0.4 11.1 6.0 2.3 1 1 0 1 1 1 0 Apx/Shroom domain ASD1 ASD2 PF08687.11 CBY39036.1 - 5.3e-24 85.3 3.4 5.3e-24 85.3 3.4 2.1 2 0 0 2 2 2 2 Apx/Shroom domain ASD2 EGF PF00008.27 CBY39037.1 - 1.1e-64 214.2 256.8 6.5e-06 26.3 8.8 18.5 18 0 0 18 18 18 17 EGF-like domain hEGF PF12661.7 CBY39037.1 - 1.4e-49 165.1 234.5 3.8e-06 27.3 1.3 20.2 18 1 0 18 18 18 15 Human growth factor-like EGF EGF_2 PF07974.13 CBY39037.1 - 5.6e-19 68.2 306.5 0.011 16.1 7.4 18.4 18 0 0 18 18 18 17 EGF-like domain FXa_inhibition PF14670.6 CBY39037.1 - 5.5e-06 26.6 221.4 0.58 10.5 5.1 18.7 9 5 9 18 18 18 9 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY39037.1 - 0.0008 19.5 234.7 0.056 13.6 0.6 19.6 11 6 6 17 17 17 12 EGF domain Plasmod_Pvs28 PF06247.11 CBY39037.1 - 0.0066 16.7 7.6 0.0066 16.7 7.6 16.0 16 0 0 16 16 16 6 Pvs28 EGF domain EGF_CA PF07645.15 CBY39037.1 - 0.011 16.0 295.8 0.047 13.9 10.5 18.4 5 5 13 18 18 18 0 Calcium-binding EGF domain Beta-prism_lec PF16458.5 CBY39037.1 - 0.12 12.3 0.0 0.92 9.5 0.0 2.4 3 0 0 3 3 3 0 Beta-prism lectin C2 PF00168.30 CBY39039.1 - 0.0035 17.6 0.1 0.0037 17.5 0.1 1.1 1 0 0 1 1 1 1 C2 domain Mito_fiss_reg PF05308.11 CBY39040.1 - 1.7 8.7 16.0 0.7 9.9 8.0 2.4 2 1 0 2 2 2 0 Mitochondrial fission regulator LIM_bind PF01803.16 CBY39041.1 - 0.042 13.4 0.9 0.14 11.7 0.1 2.1 3 0 0 3 3 3 0 LIM-domain binding protein DUF5345 PF17280.2 CBY39041.1 - 0.06 13.3 0.0 0.06 13.3 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5345) DUF389 PF04087.14 CBY39041.1 - 0.9 9.6 6.9 5.6 7.0 1.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF389) DUF2393 PF09624.10 CBY39041.1 - 1.7 8.7 6.3 11 6.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF373 PF04123.13 CBY39041.1 - 8.8 5.7 12.7 5.2 6.4 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Peptidase_M99_C PF17129.4 CBY39042.1 - 0.087 13.0 0.7 15 5.8 0.0 3.6 2 1 1 3 3 3 0 C-terminal domain of metallo-carboxypeptidase C8 PF08742.11 CBY39042.1 - 0.087 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 C8 domain Pecanex_C PF05041.15 CBY39044.1 - 2.5e-55 187.5 0.4 4.1e-55 186.8 0.4 1.3 1 0 0 1 1 1 1 Pecanex protein (C-terminus) IL6Ra-bind PF09240.10 CBY39046.1 - 0.017 15.5 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding Rad52_Rad22 PF04098.15 CBY39046.1 - 0.063 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Transmemb_17 PF09799.9 CBY39048.1 - 0.003 18.1 2.0 0.0054 17.3 2.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein PIG-Y PF15159.6 CBY39048.1 - 0.06 14.3 1.8 0.16 12.9 1.8 1.7 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pkinase PF00069.25 CBY39049.1 - 6.2e-68 229.0 0.0 8.8e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39049.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39049.1 - 5.7e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY39049.1 - 0.00014 21.0 9.9 0.002 17.1 9.9 2.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY39049.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY39049.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CBY39049.1 - 0.18 11.2 0.1 0.65 9.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BACK PF07707.15 CBY39053.1 - 3.7e-12 46.2 0.7 8.8e-12 45.0 0.5 1.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CBY39053.1 - 1.4e-11 44.6 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PDE4_UCR PF18100.1 CBY39053.1 - 0.016 15.8 0.7 0.048 14.3 0.1 2.1 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) NPH3 PF03000.14 CBY39053.1 - 0.063 12.9 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 NPH3 family Smr PF01713.21 CBY39054.1 - 5.4e-10 39.5 0.1 1.2e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 CBY39054.1 - 1.4e-06 28.6 9.4 2.6e-06 27.7 9.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) AAA_33 PF13671.6 CBY39055.1 - 0.00017 21.8 0.0 0.00035 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CBY39055.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SRP54 PF00448.22 CBY39055.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.6 CBY39055.1 - 0.0069 16.8 0.9 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.6 CBY39055.1 - 0.0075 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBY39055.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBY39055.1 - 0.008 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CBY39055.1 - 0.011 16.2 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CBY39055.1 - 0.015 15.7 0.1 0.034 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain UIM PF02809.20 CBY39055.1 - 0.033 14.1 0.3 0.068 13.1 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Zeta_toxin PF06414.12 CBY39055.1 - 0.039 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 CBY39055.1 - 0.052 13.5 0.2 0.091 12.7 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 CBY39055.1 - 0.057 13.0 0.1 0.47 10.0 0.0 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CBY39055.1 - 0.061 13.9 1.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBY39055.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CBY39055.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 CBY39055.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 CBY39055.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBY39055.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UCH PF00443.29 CBY39056.1 - 2.1e-20 73.3 2.6 2.1e-20 73.3 2.6 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 CBY39056.1 - 6.6e-08 31.9 10.1 0.00014 21.5 1.7 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif UCH_1 PF13423.6 CBY39056.1 - 0.0012 18.6 7.5 0.0099 15.5 0.3 3.3 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase RAP80_UIM PF18282.1 CBY39056.1 - 2.3 8.0 9.1 0.52 10.1 5.0 2.0 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif P_C PF06640.11 CBY39057.1 - 1.4 9.0 5.7 1.9 8.6 5.7 1.2 1 0 0 1 1 1 0 P protein C-terminus VWA PF00092.28 CBY39058.1 - 7.6e-35 120.7 19.3 1.9e-30 106.4 0.2 6.1 6 1 0 6 6 6 3 von Willebrand factor type A domain MIEAP PF16026.5 CBY39058.1 - 9 6.5 9.0 0.76 10.0 1.0 3.3 2 1 1 3 3 3 0 Mitochondria-eating protein zf-FLZ PF04570.14 CBY39059.1 - 0.029 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 PIG-X PF08320.12 CBY39060.1 - 0.96 9.3 3.2 0.81 9.6 0.1 2.2 2 1 1 3 3 3 0 PIG-X / PBN1 LGFP PF08310.11 CBY39061.1 - 0.15 12.6 0.9 0.41 11.2 0.0 2.1 3 0 0 3 3 3 0 LGFP repeat bZIP_2 PF07716.15 CBY39062.1 - 7.4e-15 54.8 10.9 1.5e-14 53.8 10.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY39062.1 - 8.9e-06 25.7 11.0 1.6e-05 24.9 11.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Alpha-mann_mid PF09261.11 CBY39062.1 - 0.0059 16.7 0.9 0.01 16.0 0.5 1.7 1 1 0 1 1 1 1 Alpha mannosidase middle domain NAM-associated PF14303.6 CBY39062.1 - 0.013 16.3 11.3 0.013 16.3 11.3 1.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain FXR_C1 PF16096.5 CBY39062.1 - 0.017 15.3 0.3 0.017 15.3 0.3 2.5 2 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 EB1_binding PF05937.11 CBY39062.1 - 0.068 13.8 8.1 0.084 13.5 6.8 1.7 1 1 0 1 1 1 0 EB-1 Binding Domain bZIP_Maf PF03131.17 CBY39062.1 - 0.12 12.9 9.4 0.54 10.8 9.1 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Phospholip_A2_1 PF00068.19 CBY39064.1 - 4.8e-18 65.7 11.2 4.8e-18 65.7 11.2 1.5 2 0 0 2 2 2 1 Phospholipase A2 Arf PF00025.21 CBY39065.1 - 2.7e-57 193.0 0.0 3.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY39065.1 - 2.1e-12 47.3 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY39065.1 - 6.8e-11 41.9 0.0 9.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBY39065.1 - 8e-11 41.8 0.0 9.5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY39065.1 - 6.1e-09 35.5 0.2 4.2e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY39065.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY39065.1 - 0.002 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY39065.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 CBY39067.1 - 2.2e-57 193.3 0.0 2.7e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBY39067.1 - 1.8e-12 47.5 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY39067.1 - 3.9e-11 42.7 0.0 5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBY39067.1 - 7.8e-11 41.8 0.0 9.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBY39067.1 - 3.8e-08 32.9 0.1 9.9e-06 24.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY39067.1 - 9.7e-08 31.6 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY39067.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBY39067.1 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MeaB PF03308.16 CBY39067.1 - 0.024 13.6 0.0 4 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Med29 PF11568.8 CBY39067.1 - 0.17 12.1 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF3558 PF12079.8 CBY39069.1 - 0.68 9.9 10.6 1.4 8.8 10.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) TYA PF01021.19 CBY39069.1 - 2.4 8.6 10.1 2.1 8.7 4.3 2.9 2 1 1 3 3 3 0 TYA transposon protein Dicty_REP PF05086.12 CBY39069.1 - 2.4 6.0 6.0 3.1 5.7 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBY39069.1 - 6.2 6.8 29.3 13 5.8 29.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FPP PF05911.11 CBY39070.1 - 0.00047 18.5 15.3 0.00054 18.3 15.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 CBY39070.1 - 0.0034 17.3 19.1 0.0043 16.9 19.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH IFT57 PF10498.9 CBY39070.1 - 0.006 15.6 13.1 0.008 15.2 13.1 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DivIC PF04977.15 CBY39070.1 - 0.0091 15.7 4.2 0.0091 15.7 4.2 2.6 1 1 2 3 3 3 1 Septum formation initiator GAS PF13851.6 CBY39070.1 - 0.0096 15.3 24.9 0.021 14.2 18.1 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CBY39070.1 - 0.032 13.1 21.5 0.039 12.8 21.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Sharpin_PH PF16764.5 CBY39070.1 - 0.042 13.6 0.7 0.079 12.7 0.7 1.5 1 1 0 1 1 1 0 Sharpin PH domain SOGA PF11365.8 CBY39070.1 - 0.05 14.7 6.5 0.05 14.7 6.5 2.3 1 1 1 2 2 2 0 Protein SOGA Atg14 PF10186.9 CBY39070.1 - 0.067 12.3 17.4 0.083 12.0 17.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 CBY39070.1 - 0.071 13.7 22.9 0.44 11.2 21.0 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF123 PF01986.16 CBY39070.1 - 0.11 13.1 1.2 0.13 12.8 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF123 MCC-bdg_PDZ PF10506.9 CBY39070.1 - 0.12 12.4 14.1 0.46 10.5 4.6 2.8 2 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Leu_zip PF15294.6 CBY39070.1 - 0.13 11.8 18.8 0.33 10.4 18.8 1.6 1 1 0 1 1 1 0 Leucine zipper Macoilin PF09726.9 CBY39070.1 - 0.23 10.0 17.1 0.029 12.9 3.9 2.0 1 1 1 2 2 2 0 Macoilin family V_ATPase_I PF01496.19 CBY39070.1 - 0.23 9.3 6.8 0.24 9.2 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 CBY39070.1 - 0.26 10.7 20.0 0.34 10.3 20.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fez1 PF06818.15 CBY39070.1 - 0.46 10.9 23.4 5.6 7.4 14.3 2.1 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 CBY39070.1 - 0.63 10.1 24.9 0.52 10.3 8.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.15 CBY39070.1 - 0.67 9.5 8.9 0.74 9.3 8.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 CBY39070.1 - 0.8 10.2 27.2 2.5 8.6 25.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBY39070.1 - 1.3 8.2 17.0 0.14 11.4 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 CBY39070.1 - 1.4 8.1 13.3 1.9 7.6 13.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Seadorna_VP6 PF07407.11 CBY39070.1 - 1.8 7.4 4.2 2.1 7.2 4.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF641 PF04859.12 CBY39070.1 - 6.9 7.0 16.4 29 5.0 15.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Histone PF00125.24 CBY39072.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY39072.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY39072.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY39072.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY39072.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CBY39073.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY39073.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY39073.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBY39074.1 - 2.4e-08 34.1 0.0 2.6e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CBY39074.1 - 4.8e-05 23.7 0.1 5.9e-05 23.4 0.1 1.2 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 CBY39074.1 - 5.8e-05 23.2 0.1 6.6e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBY39074.1 - 0.00013 22.3 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY39074.1 - 0.00021 21.5 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CBY39074.1 - 0.0065 16.5 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY39074.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY39074.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YHYH PF14240.6 CBY39075.1 - 5.5e-12 46.0 0.0 8.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 YHYH protein MARVEL PF01284.23 CBY39076.1 - 7.4e-06 26.1 0.0 7.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Snf7 PF03357.21 CBY39077.1 - 3.4e-13 49.6 16.1 4.2e-13 49.3 14.0 1.9 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.14 CBY39077.1 - 1.7e-05 24.8 3.9 2.3e-05 24.4 3.9 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 CBY39077.1 - 0.055 13.1 0.2 0.12 12.0 0.1 1.6 1 1 1 2 2 2 0 Dimethlysulfonioproprionate lyase YlqD PF11068.8 CBY39077.1 - 0.12 12.8 11.2 1.2 9.5 0.4 2.3 1 1 0 2 2 2 0 YlqD protein DUF4363 PF14276.6 CBY39077.1 - 0.24 11.5 2.9 16 5.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) T2SSM PF04612.12 CBY39077.1 - 0.64 10.1 7.7 0.091 12.8 1.8 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M SNARE PF05739.19 CBY39077.1 - 1.4 9.0 3.8 7.7 6.6 0.5 3.3 2 1 1 3 3 3 0 SNARE domain YlbD_coat PF14071.6 CBY39077.1 - 4.1 7.7 7.3 0.42 10.9 1.0 2.2 1 1 1 2 2 2 0 Putative coat protein PepSY_TM_like_2 PF16357.5 CBY39078.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.5 1 1 0 1 1 1 0 Putative PepSY_TM-like Metallophos PF00149.28 CBY39079.1 - 7.5e-24 85.4 0.0 1.5e-23 84.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY39079.1 - 0.047 13.9 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RBD-FIP PF09457.10 CBY39080.1 - 1.4e-05 24.9 0.9 1.4e-05 24.9 0.9 2.8 3 0 0 3 3 3 1 FIP domain THOC7 PF05615.13 CBY39080.1 - 0.0012 19.1 18.3 0.0012 19.1 18.3 3.8 1 1 2 4 4 4 1 Tho complex subunit 7 DUF724 PF05266.14 CBY39080.1 - 0.55 10.0 42.9 0.47 10.2 3.9 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HOOK PF05622.12 CBY39080.1 - 0.57 8.3 56.6 0.073 11.2 18.6 2.7 1 1 1 2 2 2 0 HOOK protein SNCAIP_SNCA_bd PF16700.5 CBY39080.1 - 0.97 9.2 7.7 0.084 12.6 1.5 2.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF357 PF04010.13 CBY39080.1 - 1 9.5 3.2 7.6 6.7 0.2 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF357) Jnk-SapK_ap_N PF09744.9 CBY39080.1 - 3.2 8.0 59.8 2.1 8.6 2.6 4.4 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Filament PF00038.21 CBY39080.1 - 4.1 6.9 52.9 3.3 7.2 12.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 CBY39080.1 - 4.8 7.7 61.7 19 5.8 18.3 4.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 CBY39080.1 - 6.8 5.5 55.1 7 5.4 32.1 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 CBY39080.1 - 7.5 7.5 49.9 2.5 9.0 16.2 3.8 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF2935 PF11155.8 CBY39080.1 - 9.9 6.5 19.6 2.8 8.3 3.6 3.2 2 1 2 4 4 4 0 Domain of unknown function (DUF2935) CEP63 PF17045.5 CBY39080.1 - 10 6.0 53.4 2.3e+02 1.5 42.5 2.4 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa C1q PF00386.21 CBY39083.1 - 4.6e-06 26.9 0.1 6.2e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 CBY39083.1 - 0.00036 20.4 0.7 0.00047 20.1 0.7 1.1 1 0 0 1 1 1 1 BclA C-terminal domain eIF-5a PF01287.20 CBY39083.1 - 0.06 13.4 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold LRR_8 PF13855.6 CBY39084.1 - 4e-37 125.8 27.2 1.1e-12 47.5 0.6 4.9 1 1 5 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 CBY39084.1 - 2.2e-13 50.3 0.2 7.4e-11 42.1 0.1 2.3 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY39084.1 - 1e-12 48.0 15.0 0.002 18.5 1.7 5.7 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY39084.1 - 0.0018 18.6 12.6 11 7.1 0.6 7.2 8 2 0 8 8 8 1 Leucine Rich Repeat LRR_9 PF14580.6 CBY39084.1 - 0.0085 15.6 4.9 0.25 10.8 0.8 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBY39084.1 - 0.41 10.8 15.3 27 5.1 0.0 6.9 8 1 0 8 8 8 0 Leucine Rich repeat Sushi PF00084.20 CBY39085.1 - 0.0051 17.4 17.5 0.035 14.7 2.6 3.5 3 0 0 3 3 3 2 Sushi repeat (SCR repeat) Asn_synthase PF00733.21 CBY39086.1 - 2.2e-23 83.5 0.0 2.8e-20 73.3 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CBY39086.1 - 2e-13 50.3 0.0 5.3e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBY39086.1 - 9.2e-09 35.6 0.0 7.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain CBM_X2 PF03442.14 CBY39086.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 EFG_C PF00679.24 CBY39087.1 - 2.9e-05 24.0 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBY39087.1 - 0.039 13.7 0.4 0.66 9.8 0.4 2.1 1 1 0 1 1 1 0 Elongation factor G, domain IV EFG_II PF14492.6 CBY39088.1 - 6.4e-15 55.0 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CBY39088.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain TSP_1 PF00090.19 CBY39089.1 - 0.0023 18.1 22.5 0.07 13.4 8.5 3.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain bVLRF1 PF18826.1 CBY39090.1 - 7.5e-33 113.5 0.0 1.7e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 CBY39090.1 - 7.1e-11 41.8 1.8 1.8e-10 40.5 1.8 1.7 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 CBY39090.1 - 1.5e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY39090.1 - 0.00053 20.5 0.0 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY39090.1 - 0.00098 19.4 0.0 0.005 17.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CBY39090.1 - 0.0014 19.2 0.0 0.015 15.9 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY39090.1 - 0.0015 18.9 0.1 0.0046 17.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat DUF4193 PF13834.6 CBY39090.1 - 1.4 9.5 5.7 9.1 6.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4193) XRN_M PF17846.1 CBY39090.1 - 10 5.0 7.7 10 4.9 5.2 2.0 2 0 0 2 2 2 0 Xrn1 helical domain CwfJ_C_2 PF04676.14 CBY39091.1 - 5.2e-18 65.7 0.0 8.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CBY39091.1 - 0.022 14.6 0.0 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 Collagen PF01391.18 CBY39092.1 - 2.7e-23 81.5 70.8 6.8e-11 41.8 26.5 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ribosomal_L27 PF01016.19 CBY39094.1 - 0.012 15.7 0.1 0.08 13.0 0.1 2.1 1 1 0 1 1 1 0 Ribosomal L27 protein Coq4 PF05019.13 CBY39095.1 - 3.5e-71 239.1 0.0 4.4e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Ribosomal_L37 PF08561.10 CBY39096.1 - 0.0013 19.2 4.7 0.0016 18.9 4.7 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 A_deamin PF02137.18 CBY39097.1 - 1.4e-34 120.0 0.0 1.6e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank_5 PF13857.6 CBY39099.1 - 4.4e-05 23.7 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY39099.1 - 0.036 14.5 3.1 0.63 10.6 0.1 3.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 CBY39099.1 - 0.041 14.5 0.0 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY39099.1 - 0.12 13.0 0.0 42 4.9 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) polyprenyl_synt PF00348.17 CBY39100.1 - 4.8e-81 271.6 0.4 5.7e-81 271.3 0.4 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CBY39101.1 - 2.4e-63 214.0 0.0 2.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39101.1 - 1.5e-23 83.4 0.0 1.8e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39101.1 - 4.4e-05 23.0 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY39101.1 - 0.0016 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY39101.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IIGP PF05049.13 CBY39102.1 - 3.4e-19 69.1 0.1 4.6e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 CBY39102.1 - 2e-05 24.6 0.0 4.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 CBY39102.1 - 0.00024 21.1 0.2 0.00051 20.0 0.2 1.6 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBY39102.1 - 0.00066 20.2 0.1 0.0029 18.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CBY39102.1 - 0.0039 17.1 0.1 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBY39102.1 - 0.0074 16.6 0.1 0.015 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBY39102.1 - 0.014 14.9 0.0 0.05 13.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CBY39102.1 - 0.024 14.4 0.2 0.048 13.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBY39102.1 - 0.025 15.1 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CBY39102.1 - 0.035 13.6 0.8 0.19 11.3 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 CBY39102.1 - 0.052 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CBY39102.1 - 0.073 13.3 1.8 0.32 11.2 0.4 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Atrophin-1 PF03154.15 CBY39102.1 - 3.5 5.8 7.3 4 5.6 7.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Zip PF02535.22 CBY39103.1 - 3.9e-19 69.1 15.9 1.9e-18 66.8 3.8 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter HlyIII PF03006.20 CBY39103.1 - 0.058 13.1 3.5 0.1 12.3 0.7 2.3 2 0 0 2 2 2 0 Haemolysin-III related MerC PF03203.14 CBY39103.1 - 0.58 10.6 8.9 0.029 14.8 2.0 2.4 2 1 1 3 3 3 0 MerC mercury resistance protein SSP160 PF06933.11 CBY39104.1 - 0.0017 16.7 48.3 0.17 10.0 16.0 3.2 3 0 0 3 3 3 3 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 CBY39104.1 - 0.0074 16.5 29.2 0.37 11.0 3.5 3.2 3 0 0 3 3 3 3 AJAP1/PANP C-terminus Mucin PF01456.17 CBY39104.1 - 0.019 15.0 64.2 0.11 12.5 16.5 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein PDZ PF00595.24 CBY39106.1 - 6.6e-90 295.6 3.3 1.6e-13 50.8 0.0 9.3 9 0 0 9 9 9 9 PDZ domain PDZ_6 PF17820.1 CBY39106.1 - 4.8e-85 279.3 17.9 1.6e-12 47.1 0.0 9.0 9 0 0 9 9 9 8 PDZ domain PDZ_2 PF13180.6 CBY39106.1 - 5.3e-42 142.0 12.4 3.2e-07 30.6 0.0 9.0 9 0 0 9 9 9 7 PDZ domain Tricorn_PDZ PF14685.6 CBY39106.1 - 1.2e-06 28.4 11.3 0.39 10.7 0.0 6.8 7 0 0 7 7 7 3 Tricorn protease PDZ domain Tetraspanin PF00335.20 CBY39106.1 - 2.2e-05 24.3 3.8 3.7e-05 23.5 3.8 1.2 1 0 0 1 1 1 1 Tetraspanin family PDZ_4 PF17816.1 CBY39106.1 - 0.00078 19.8 3.8 1.7 9.0 0.0 5.4 5 1 1 6 6 6 1 PDZ domain RPAP1_C PF08620.10 CBY39106.1 - 0.018 15.2 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 RPAP1-like, C-terminal Hormone_recep PF00104.30 CBY39107.1 - 7.8e-07 28.9 0.7 7.8e-07 28.9 0.7 1.7 2 0 0 2 2 2 1 Ligand-binding domain of nuclear hormone receptor zf-C4 PF00105.18 CBY39108.1 - 2.8e-08 34.1 0.8 7.5e-08 32.7 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C4 type (two domains) WD40_3 PF15911.5 CBY39109.1 - 2.5e-09 37.0 0.0 9.4e-09 35.2 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY39109.1 - 7.1e-07 29.4 1.1 0.43 10.9 0.1 5.7 3 2 3 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CBY39109.1 - 1.1e-06 28.6 1.7 1.4 8.8 0.1 5.0 4 0 0 4 4 4 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 CBY39109.1 - 2.6e-06 26.7 7.4 0.031 13.3 0.3 5.6 5 1 2 7 7 7 2 Coatomer WD associated region TPR_14 PF13428.6 CBY39109.1 - 0.00018 22.1 3.9 1.1 10.3 0.1 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY39109.1 - 0.00087 19.8 6.7 2.8 8.5 0.2 5.9 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY39109.1 - 0.0011 18.9 18.6 9.2 6.7 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39109.1 - 0.0012 19.0 6.4 4 7.7 0.0 5.8 6 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBY39109.1 - 0.29 11.3 11.9 44 4.4 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat WD40 PF00400.32 CBY39109.1 - 0.3 12.0 6.9 1.7e+02 3.4 0.1 6.2 5 1 1 6 6 6 0 WD domain, G-beta repeat TPR_8 PF13181.6 CBY39109.1 - 0.31 11.3 11.4 2.5 8.6 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY39109.1 - 0.31 10.7 5.7 19 5.1 0.1 4.5 4 0 0 4 4 4 0 TPR repeat TPR_12 PF13424.6 CBY39109.1 - 0.51 10.7 8.5 41 4.5 0.3 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY39109.1 - 0.9 9.5 13.8 20 5.2 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 CBY39109.1 - 1.2 9.2 7.1 4 7.5 7.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon CHD5 PF04420.14 CBY39110.1 - 1.5e-12 47.7 1.0 2.7e-12 46.8 1.0 1.4 1 1 0 1 1 1 1 CHD5-like protein dNK PF01712.19 CBY39111.1 - 5.8e-62 209.2 0.0 6.9e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 CBY39111.1 - 3.9e-05 24.2 2.2 0.00077 20.0 0.2 3.0 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CBY39111.1 - 0.0024 17.6 0.9 0.077 12.7 0.0 2.6 2 1 1 3 3 3 1 Thymidylate kinase AAA_33 PF13671.6 CBY39111.1 - 0.032 14.4 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Spore_IV_A PF09547.10 CBY39111.1 - 0.13 11.2 0.6 2.4 7.0 0.0 2.0 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) Gp58 PF07902.11 CBY39111.1 - 0.16 10.2 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein ASH PF15780.5 CBY39112.1 - 1.2e-13 51.0 8.8 0.0037 17.4 0.1 5.7 5 1 2 7 7 7 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBY39112.1 - 3.6e-05 23.6 5.5 0.43 10.4 0.0 4.8 5 1 0 5 5 5 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBY39112.1 - 0.00015 21.8 0.2 1.4 8.9 0.1 5.1 4 2 1 5 5 5 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 CBY39112.1 - 0.019 15.2 4.2 2.8 8.2 0.0 3.9 4 0 0 4 4 4 0 Transmembrane protein 131-like DUF202 PF02656.15 CBY39115.1 - 0.17 12.4 3.1 0.84 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) zf-C2H2_4 PF13894.6 CBY39117.1 - 0.014 16.2 5.0 0.022 15.5 3.0 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 CBY39117.1 - 0.023 15.0 0.4 0.048 14.0 0.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CBY39117.1 - 0.38 11.3 7.3 0.19 12.2 3.3 2.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CBY39117.1 - 0.38 11.4 1.5 0.7 10.6 0.3 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 CBY39117.1 - 0.47 10.4 4.5 1.1 9.2 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF4674 PF15719.5 CBY39117.1 - 2.8 8.0 10.6 0.17 11.9 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4674) COesterase PF00135.28 CBY39118.1 - 1.4e-49 169.4 0.0 1.6e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY39118.1 - 5.8e-09 36.1 1.6 3.2e-08 33.7 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Kelch_3 PF13415.6 CBY39119.1 - 6.4e-23 80.5 8.1 5.9e-11 42.4 0.1 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY39119.1 - 1.6e-19 69.6 10.6 2e-05 24.5 0.0 6.5 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY39119.1 - 1.5e-17 63.1 7.2 8.2e-05 22.7 0.2 6.1 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 CBY39119.1 - 2.7e-17 62.3 0.1 8.7e-08 32.0 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CBY39119.1 - 1.3e-14 53.5 14.7 4.7e-07 29.3 0.1 6.7 7 1 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBY39119.1 - 1.1e-11 44.2 6.4 1.5e-05 24.8 0.2 5.9 6 0 0 6 6 6 2 Kelch motif Sec1 PF00995.23 CBY39120.1 - 1.2e-82 279.0 11.1 1.5e-82 278.7 11.1 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 CBY39121.1 - 3e-105 353.6 4.9 3.5e-105 353.4 4.9 1.0 1 0 0 1 1 1 1 Sec1 family LMBR1 PF04791.16 CBY39121.1 - 0.17 10.7 1.5 0.23 10.3 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Swi3 PF07962.12 CBY39121.1 - 0.21 11.6 1.0 0.59 10.2 1.0 1.7 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DHR10 PF18595.1 CBY39121.1 - 0.58 10.2 5.7 2.5 8.2 6.0 1.9 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Myosin_head PF00063.21 CBY39123.1 - 2.1e-155 518.7 0.7 7.5e-155 516.9 0.7 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) RhoGAP PF00620.27 CBY39123.1 - 1.5e-37 128.8 0.1 4.1e-37 127.4 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain IQ PF00612.27 CBY39123.1 - 2.9e-10 39.0 33.3 0.0002 20.8 0.2 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif RA PF00788.23 CBY39123.1 - 5.6e-07 30.1 0.0 2.9e-06 27.8 0.0 2.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain C1_1 PF00130.22 CBY39123.1 - 1.3e-06 28.2 7.3 2.9e-06 27.1 7.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 CBY39123.1 - 0.00044 20.4 3.7 0.0014 18.8 3.7 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_16 PF13191.6 CBY39123.1 - 0.0012 19.3 0.4 0.027 14.9 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.13 CBY39123.1 - 0.018 14.1 0.9 0.89 8.5 0.1 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 CBY39123.1 - 0.041 14.2 0.1 0.98 9.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain HAD_SAK_2 PF18143.1 CBY39123.1 - 0.045 14.1 3.7 0.22 11.8 0.7 3.1 2 1 1 3 3 3 0 HAD domain in Swiss Army Knife RNA repair proteins T2SSE PF00437.20 CBY39123.1 - 0.089 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-RING_9 PF13901.6 CBY39123.1 - 0.23 11.4 10.9 0.038 14.0 4.7 2.6 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 CBY39123.1 - 0.27 11.6 2.4 0.64 10.4 2.4 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 CBY39123.1 - 0.47 10.1 1.8 1.1 8.9 1.8 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 CBY39123.1 - 0.49 10.5 3.4 1.3 9.2 3.4 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CBY39123.1 - 0.88 9.5 3.4 1.9 8.5 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBY39123.1 - 2 8.3 4.4 5.3 7.0 4.4 1.7 1 0 0 1 1 1 0 PHD-finger DUF572 PF04502.13 CBY39124.1 - 1.2e-48 166.5 6.4 9.2e-48 163.6 5.4 1.8 1 1 1 2 2 2 2 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 CBY39124.1 - 0.075 12.8 5.0 0.11 12.2 5.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 CBY39126.1 - 1.3e-64 218.1 0.0 2.4e-64 217.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39126.1 - 9.1e-34 116.9 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39126.1 - 1.9e-05 24.2 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY39126.1 - 8.3e-05 21.7 0.0 0.0037 16.3 0.0 2.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY39126.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY39126.1 - 0.0018 17.7 0.2 0.006 16.0 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4990 PF16380.5 CBY39126.1 - 0.08 13.0 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Seadorna_VP7 PF07387.11 CBY39126.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Na_sulph_symp PF00939.19 CBY39127.1 - 7.3e-89 299.0 23.5 1.1e-88 298.3 23.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY39127.1 - 1.7e-30 106.3 32.9 9.3e-15 54.6 6.4 3.2 2 1 0 3 3 3 3 Citrate transporter DUF2407_C PF13373.6 CBY39127.1 - 0.13 12.5 0.1 0.38 10.9 0.1 1.8 1 0 0 1 1 1 0 DUF2407 C-terminal domain RRM_1 PF00076.22 CBY39128.1 - 1.5e-10 40.7 0.0 2.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBY39128.1 - 0.0073 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CBY39128.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Borrelia_P83 PF05262.11 CBY39128.1 - 0.051 12.1 0.5 0.059 11.8 0.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_occluded PF16842.5 CBY39128.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif IF-2B PF01008.17 CBY39129.1 - 2.4e-39 135.3 0.8 4.1e-39 134.5 0.8 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DLIC PF05783.11 CBY39130.1 - 3.4e-56 191.1 0.0 5.1e-29 101.4 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 CBY39130.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBY39130.1 - 0.031 13.9 0.1 0.6 9.7 0.1 2.6 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.27 CBY39130.1 - 0.057 13.9 0.1 0.44 11.1 0.0 2.3 2 1 0 2 2 2 0 ABC transporter PHD PF00628.29 CBY39131.1 - 0.00072 19.4 5.2 0.0013 18.6 5.2 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 CBY39131.1 - 0.032 14.1 0.7 0.064 13.2 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CBY39131.1 - 0.49 10.5 4.3 1.1 9.4 4.3 1.6 1 0 0 1 1 1 0 PHD-finger SAC3_GANP PF03399.16 CBY39132.1 - 5.4e-26 91.6 3.3 1.7e-24 86.7 3.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CBY39132.1 - 6.2e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RPN7 PF10602.9 CBY39132.1 - 0.00076 19.2 0.8 0.0015 18.3 0.8 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Tudor_2 PF18104.1 CBY39132.1 - 0.44 10.3 1.3 3.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain zf-C2H2 PF00096.26 CBY39133.1 - 9.1e-09 35.3 31.2 0.00028 21.2 0.9 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY39133.1 - 1.8e-07 31.4 30.7 0.00075 20.1 0.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY39133.1 - 3e-06 27.4 24.8 0.01 16.1 0.7 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CBY39133.1 - 1.9e-05 24.3 28.0 0.00015 21.4 1.6 3.7 3 1 0 3 3 3 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 CBY39133.1 - 2.2e-05 24.7 21.1 0.0032 17.8 0.4 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 CBY39133.1 - 0.0012 19.1 22.1 0.14 12.5 0.9 3.6 1 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CBY39133.1 - 0.0027 18.0 26.8 0.007 16.7 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type PyrI_C PF02748.15 CBY39133.1 - 0.0082 16.0 7.7 0.7 9.9 1.3 2.8 1 1 1 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_ribbon_SprT PF17283.2 CBY39133.1 - 0.027 14.4 15.0 1.3 9.0 0.2 4.3 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-C2HE PF16278.5 CBY39133.1 - 0.044 14.2 7.0 0.044 14.2 7.0 3.6 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-SNAP50_C PF12251.8 CBY39133.1 - 0.044 13.5 15.7 0.093 12.4 3.0 2.1 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal PHD_4 PF16866.5 CBY39133.1 - 0.26 11.4 5.8 2.9 8.0 0.4 2.4 2 1 0 2 2 2 0 PHD-finger LIM PF00412.22 CBY39133.1 - 0.84 9.9 17.6 1.5 9.2 11.0 3.1 1 1 2 3 3 3 0 LIM domain zf-nanos PF05741.13 CBY39133.1 - 1.8 8.9 21.2 1.2 9.5 0.8 4.1 2 1 1 3 3 3 0 Nanos RNA binding domain HNH_5 PF14279.6 CBY39133.1 - 4.8 7.1 12.2 9.3 6.2 0.3 3.7 3 1 0 3 3 3 0 HNH endonuclease Fam20C PF06702.12 CBY39134.1 - 6.8e-84 281.1 0.1 1.1e-83 280.4 0.1 1.3 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 FAM198 PF15051.6 CBY39134.1 - 0.073 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 FAM198 protein Mucin PF01456.17 CBY39134.1 - 0.47 10.4 12.3 0.74 9.8 12.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGAP PF00620.27 CBY39135.1 - 2.2e-24 86.0 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Trypsin PF00089.26 CBY39136.1 - 2.8e-40 138.5 0.0 4.6e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY39136.1 - 7.1e-06 26.4 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY39136.1 - 0.00013 22.9 0.0 0.00031 21.7 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain USP7_ICP0_bdg PF12436.8 CBY39137.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 PRK PF00485.18 CBY39138.1 - 0.00015 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family WD40 PF00400.32 CBY39139.1 - 1.5e-32 111.1 8.4 4.7e-06 27.2 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY39139.1 - 2.8e-09 37.1 0.2 0.067 13.5 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY39139.1 - 0.0047 15.6 0.1 1.7 7.2 0.0 3.6 2 1 2 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CBY39139.1 - 0.0089 15.6 0.0 0.077 12.6 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 CBY39139.1 - 0.017 14.5 0.0 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain DUF778 PF05608.12 CBY39140.1 - 1.1e-41 143.3 4.8 2.4e-22 80.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CBY39140.1 - 0.014 15.0 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 CBY39140.1 - 0.043 13.7 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain UbiA PF01040.18 CBY39141.1 - 1.4e-29 103.1 5.5 2e-29 102.6 5.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Sec6 PF06046.13 CBY39142.1 - 7.3e-33 113.8 0.1 2.9e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 CBY39142.1 - 0.026 13.5 7.0 0.23 10.4 4.8 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal Dynactin_p22 PF07426.11 CBY39142.1 - 0.3 10.9 6.2 0.27 11.1 4.6 1.7 1 1 0 1 1 1 0 Dynactin subunit p22 LapD_MoxY_N PF16448.5 CBY39142.1 - 0.41 10.6 1.9 0.88 9.5 0.3 2.0 1 1 1 2 2 2 0 LapD/MoxY periplasmic domain CorA PF01544.18 CBY39142.1 - 0.47 9.7 4.8 0.82 8.9 4.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sec8_exocyst PF04048.14 CBY39142.1 - 0.83 9.5 5.6 0.17 11.8 1.0 2.2 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain MCM6_C PF18263.1 CBY39142.1 - 2.4 8.4 6.1 6.6 7.0 2.2 3.1 2 1 1 3 3 3 0 MCM6 C-terminal winged-helix domain SOAR PF16533.5 CBY39142.1 - 4.2 7.4 7.1 0.55 10.2 1.3 2.6 3 0 0 3 3 3 0 STIM1 Orai1-activating region PCRF PF03462.18 CBY39142.1 - 4.2 7.2 9.3 1.9 8.3 3.6 2.3 1 1 1 2 2 2 0 PCRF domain Sec6 PF06046.13 CBY39143.1 - 9.5e-37 126.6 0.1 1.1e-36 126.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF4179 PF13786.6 CBY39143.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1706 PF08020.11 CBY39143.1 - 0.12 12.3 0.3 0.31 11.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) DZF PF07528.14 CBY39144.1 - 1.6e-13 50.9 0.0 1.3e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 DZF domain HBS1_N PF08938.10 CBY39144.1 - 0.074 13.4 0.2 1 9.7 0.1 2.3 2 0 0 2 2 2 0 HBS1 N-terminus SF-assemblin PF06705.11 CBY39145.1 - 0.0036 16.7 4.7 0.0043 16.4 4.7 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.18 CBY39145.1 - 0.0046 16.9 6.1 0.01 15.7 6.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Leu_zip PF15294.6 CBY39145.1 - 0.0059 16.2 7.6 0.008 15.7 7.6 1.2 1 0 0 1 1 1 1 Leucine zipper LIN37 PF15306.6 CBY39145.1 - 0.053 13.7 2.3 0.06 13.6 2.3 1.1 1 0 0 1 1 1 0 LIN37 ZYG-11_interact PF05884.12 CBY39145.1 - 0.06 12.7 1.5 0.071 12.5 1.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Mto2_bdg PF12808.7 CBY39145.1 - 0.062 13.6 1.7 0.15 12.4 1.7 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RRF PF01765.19 CBY39145.1 - 0.076 13.0 7.0 0.086 12.8 6.3 1.4 1 1 0 1 1 1 0 Ribosome recycling factor HSCB_C PF07743.13 CBY39145.1 - 0.096 13.2 0.7 0.096 13.2 0.7 2.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain V-ATPase_G PF03179.15 CBY39145.1 - 0.14 12.7 10.6 0.041 14.4 7.3 1.7 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Gp-FAR-1 PF05823.12 CBY39145.1 - 0.24 11.7 7.3 0.055 13.8 3.2 2.0 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DivIVA PF05103.13 CBY39145.1 - 0.39 10.8 11.1 28 4.8 11.1 3.0 1 1 0 1 1 1 0 DivIVA protein TMPIT PF07851.13 CBY39145.1 - 1 8.5 6.9 1.1 8.4 6.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.13 CBY39145.1 - 1.3 9.7 3.7 0.44 11.2 0.8 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) EF-hand_7 PF13499.6 CBY39146.1 - 1.9e-08 34.6 10.7 1.8e-07 31.5 3.7 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY39146.1 - 3.2e-08 33.3 8.3 1.3e-07 31.4 4.2 3.6 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY39146.1 - 6.2e-08 31.7 14.2 0.00018 20.8 2.6 4.1 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY39146.1 - 2.8e-07 29.9 7.1 0.0028 17.5 0.5 3.8 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 CBY39146.1 - 3.4e-05 23.1 9.9 0.0025 17.3 1.9 3.5 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CBY39146.1 - 0.043 13.8 2.2 0.057 13.4 1.0 1.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3884 PF13024.6 CBY39146.1 - 0.047 13.2 0.6 0.15 11.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3884) EF-hand_11 PF08976.11 CBY39146.1 - 0.14 13.1 0.5 0.43 11.5 0.3 1.8 2 0 0 2 2 2 0 EF-hand domain SSF PF00474.17 CBY39149.1 - 3.3e-29 102.0 14.9 8.7e-29 100.6 14.9 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family FHA PF00498.26 CBY39150.1 - 4.7e-11 42.9 0.0 9.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBY39150.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Neur_chan_LBD PF02931.23 CBY39152.1 - 1.3e-39 135.8 0.0 1.8e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY39152.1 - 2.9e-17 63.5 12.5 5.7e-11 42.9 2.0 3.0 2 1 1 3 3 3 2 Neurotransmitter-gated ion-channel transmembrane region zf-CCCH PF00642.24 CBY39153.1 - 7.6e-42 140.5 38.6 1.4e-09 37.6 2.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY39153.1 - 3.6e-20 71.3 38.7 1.9e-06 27.5 2.9 5.3 5 0 0 5 5 5 5 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY39153.1 - 6.5e-19 67.3 46.4 1.1e-06 28.5 1.3 5.4 5 0 0 5 5 5 5 Zinc finger domain zf-CCCH_2 PF14608.6 CBY39153.1 - 4.2e-07 30.2 32.9 0.085 13.4 0.5 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CBY39153.1 - 6.9e-06 26.7 27.2 0.27 11.9 0.7 5.2 3 1 2 5 5 5 4 Torus domain Defensin_int PF17858.1 CBY39153.1 - 8 6.5 10.0 30 4.7 0.5 3.7 4 0 0 4 4 4 0 Platypus intermediate defensin-like peptide Ion_trans PF00520.31 CBY39154.1 - 5.9e-17 61.7 22.8 9.2e-17 61.1 22.8 1.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY39154.1 - 0.0072 15.1 20.0 0.028 13.1 11.3 2.4 1 1 1 2 2 2 2 Polycystin cation channel DUF2730 PF10805.8 CBY39154.1 - 0.017 15.2 0.3 0.039 14.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Sec34 PF04136.15 CBY39154.1 - 0.078 12.9 1.1 0.11 12.3 1.1 1.3 1 0 0 1 1 1 0 Sec34-like family Pox_A11 PF05061.13 CBY39154.1 - 0.097 11.9 0.7 0.18 11.0 0.7 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF1664 PF07889.12 CBY39154.1 - 0.18 11.8 0.8 0.33 11.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY39154.1 - 0.29 11.5 2.6 0.54 10.7 2.6 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2070 PF09843.9 CBY39154.1 - 3.9 5.7 12.6 5.9 5.0 12.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 60KD_IMP PF02096.20 CBY39154.1 - 6.3 6.7 15.3 15 5.5 0.2 3.2 3 0 0 3 3 3 0 60Kd inner membrane protein BTD PF09270.10 CBY39155.1 - 2.6e-12 47.2 0.0 4.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain OB_Dis3 PF17849.1 CBY39157.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) DUF1168 PF06658.12 CBY39158.1 - 3.4 7.5 12.7 0.48 10.2 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF4250 PF14056.6 CBY39160.1 - 0.16 11.9 0.2 0.87 9.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) RNase_T PF00929.24 CBY39161.1 - 0.015 15.8 0.0 0.022 15.3 0.0 1.3 1 1 0 1 1 1 0 Exonuclease zf-C2H2_jaz PF12171.8 CBY39162.1 - 2.3e-06 27.7 0.6 5e-06 26.7 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY39162.1 - 0.00089 19.6 0.3 0.0018 18.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CBY39162.1 - 0.0018 18.0 3.8 0.006 16.3 3.8 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 CBY39162.1 - 0.006 16.9 1.3 0.012 15.9 1.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) MRNIP PF15749.5 CBY39162.1 - 0.015 16.0 5.6 0.015 16.0 5.6 2.9 2 1 0 2 2 2 0 MRN-interacting protein Phe_ZIP PF08916.11 CBY39162.1 - 0.1 13.4 0.4 0.32 11.7 0.2 2.1 2 0 0 2 2 2 0 Phenylalanine zipper bZIP_1 PF00170.21 CBY39163.1 - 1.2e-09 38.1 11.4 4.3e-09 36.3 11.4 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY39163.1 - 4.7e-07 29.8 11.5 4.7e-07 29.8 11.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY39163.1 - 0.019 15.5 3.2 0.019 15.5 3.2 2.7 3 0 0 3 3 3 0 bZIP Maf transcription factor Aconitase_C PF00694.19 CBY39164.1 - 1.8e-32 112.4 0.0 2.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain DSBA PF01323.20 CBY39164.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CAP PF00188.26 CBY39165.1 - 7.2e-19 68.9 0.3 1e-18 68.4 0.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GCIP PF13324.6 CBY39165.1 - 0.17 11.5 2.5 0.25 10.9 2.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Phospholip_A2_1 PF00068.19 CBY39166.1 - 2.1e-13 50.7 8.5 2.1e-13 50.7 8.5 2.1 1 1 1 2 2 2 1 Phospholipase A2 Mon1 PF03164.14 CBY39167.1 - 6.5e-91 305.4 0.1 7.9e-91 305.1 0.1 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF4258 PF14076.6 CBY39167.1 - 0.051 14.0 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Rotamase_3 PF13616.6 CBY39168.1 - 3.6e-18 66.2 0.0 9.9e-18 64.8 0.0 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CBY39168.1 - 1.8e-13 51.3 0.1 5.2e-13 49.8 0.1 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain NifU_N PF01592.16 CBY39169.1 - 6.9e-50 168.5 0.7 8.6e-50 168.2 0.7 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Hexapep PF00132.24 CBY39170.1 - 1.3e-06 27.9 2.2 3.6e-05 23.3 1.9 2.4 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBY39170.1 - 0.023 14.5 1.1 0.036 13.8 0.1 1.8 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase EIF_2_alpha PF07541.12 CBY39171.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit CCDC50_N PF15295.6 CBY39171.1 - 0.098 12.8 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus zf-CCCH_7 PF18586.1 CBY39174.1 - 0.029 14.7 0.7 0.075 13.4 0.6 1.8 1 1 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Pro_Al_protease PF02983.14 CBY39174.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.6 3 0 0 3 3 3 0 Alpha-lytic protease prodomain RGCC PF15151.6 CBY39175.1 - 0.16 12.2 7.5 0.79 9.9 0.9 2.6 2 0 0 2 2 2 0 Response gene to complement 32 protein family BORG_CEP PF14957.6 CBY39175.1 - 0.52 11.5 7.4 0.14 13.4 4.0 1.9 2 1 0 2 2 2 0 Cdc42 effector CCDC53 PF10152.9 CBY39175.1 - 7.3 7.0 7.6 0.73 10.2 1.0 2.3 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Trypsin PF00089.26 CBY39176.1 - 1.8e-50 171.8 0.0 2.7e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY39176.1 - 0.0049 17.8 0.0 0.011 16.7 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain TssO PF17561.2 CBY39177.1 - 0.034 14.2 2.4 0.074 13.2 2.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Eryth_link_C PF16915.5 CBY39177.1 - 0.18 11.8 1.6 0.3 11.1 0.2 2.1 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus F-box PF00646.33 CBY39179.1 - 7.8e-05 22.4 0.1 0.002 18.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY39179.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like IBR PF01485.21 CBY39179.1 - 0.018 15.2 7.2 0.051 13.8 7.2 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3797 PF12677.7 CBY39179.1 - 0.043 13.7 2.2 0.12 12.2 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CEBP_ZZ PF16366.5 CBY39179.1 - 0.6 10.4 7.5 1.5 9.1 7.5 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AsnA PF03590.15 CBY39181.1 - 0.0021 17.8 1.5 0.057 13.2 0.3 2.4 2 0 0 2 2 2 2 Aspartate-ammonia ligase Snapin_Pallidin PF14712.6 CBY39181.1 - 0.093 13.2 0.2 0.45 11.0 0.2 2.2 1 0 0 1 1 1 0 Snapin/Pallidin O-FucT PF10250.9 CBY39182.1 - 1.1e-07 31.9 0.0 2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Med8 PF10232.9 CBY39183.1 - 1.6e-38 132.6 0.1 1.9e-38 132.3 0.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4410 PF14366.6 CBY39183.1 - 0.23 11.4 0.7 0.82 9.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) ThrE PF06738.12 CBY39183.1 - 0.27 10.6 0.1 0.6 9.4 0.1 1.5 2 0 0 2 2 2 0 Putative threonine/serine exporter RRM_1 PF00076.22 CBY39184.1 - 5.4e-14 51.8 0.0 1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOG1 PF06858.14 CBY39185.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) tRNA-synt_His PF13393.6 CBY39185.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Peptidase_M20 PF01546.28 CBY39186.1 - 9.2e-37 126.7 0.0 1.5e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBY39186.1 - 7.1e-16 58.1 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Antibiotic_NAT PF02522.14 CBY39186.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Peptidase_M28 PF04389.17 CBY39186.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Fur_reg_FbpB PF13040.6 CBY39186.1 - 0.14 11.7 0.2 0.35 10.5 0.2 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B Aminotran_3 PF00202.21 CBY39187.1 - 1.1e-104 350.3 0.0 1.4e-104 350.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FadR_C PF07840.12 CBY39187.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain BCNT PF07572.12 CBY39188.1 - 0.02 14.9 1.3 0.032 14.3 0.1 2.0 2 0 0 2 2 2 0 Bucentaur or craniofacial development Glycos_transf_2 PF00535.26 CBY39189.1 - 1.4e-20 73.8 0.0 7.8e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 RXLR_WY PF18634.1 CBY39189.1 - 0.016 15.1 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein WY-domain DUF1651 PF07864.11 CBY39189.1 - 0.054 13.9 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) DUF3895 PF13034.6 CBY39189.1 - 0.085 12.9 0.0 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) Osmo_CC PF08946.10 CBY39189.1 - 0.12 12.7 0.6 0.35 11.2 0.6 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CdiA_C PF18451.1 CBY39189.1 - 1.2 9.3 6.0 19 5.6 0.1 3.7 3 1 1 4 4 4 0 Contact-dependent growth inhibition CdiA C-terminal domain Foie-gras_1 PF11817.8 CBY39191.1 - 0.0086 15.7 0.1 0.0086 15.7 0.1 1.1 1 0 0 1 1 1 1 Foie gras liver health family 1 DZF PF07528.14 CBY39192.1 - 7.5e-18 65.1 0.2 5.3e-17 62.3 0.0 2.3 2 1 0 2 2 2 1 DZF domain dsrm PF00035.26 CBY39192.1 - 0.0074 17.0 0.0 0.021 15.5 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif CitX PF03802.14 CBY39192.1 - 0.038 13.8 1.4 0.15 11.8 0.3 2.3 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase RF-1 PF00472.20 CBY39192.1 - 8 6.4 10.3 0.19 11.7 0.6 2.7 2 1 0 2 2 2 0 RF-1 domain SecA_DEAD PF07517.14 CBY39194.1 - 2.6 7.3 7.1 2.6 7.3 0.3 2.4 2 0 0 2 2 2 0 SecA DEAD-like domain Kinesin PF00225.23 CBY39195.1 - 3.5e-07 29.5 0.2 3.5e-07 29.5 0.2 2.6 3 2 1 4 4 4 1 Kinesin motor domain Pox_A_type_inc PF04508.12 CBY39195.1 - 1.4 8.9 5.2 22 5.1 0.1 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2228 PF10228.9 CBY39195.1 - 3.1 7.5 11.9 0.14 11.9 0.9 2.6 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) PRKG1_interact PF15898.5 CBY39195.1 - 5.3 8.0 40.4 1.6 9.7 14.9 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Lectin_C PF00059.21 CBY39196.1 - 3.5e-18 66.3 6.5 1.1e-07 32.6 0.9 3.8 3 0 0 3 3 3 2 Lectin C-type domain VWD PF00094.25 CBY39196.1 - 4.7e-13 49.7 2.2 1.1e-05 25.8 0.2 2.4 2 0 0 2 2 2 2 von Willebrand factor type D domain C8 PF08742.11 CBY39196.1 - 5e-06 26.8 6.7 5e-06 26.8 6.7 3.4 1 1 1 2 2 2 1 C8 domain TIL PF01826.17 CBY39196.1 - 4e-05 23.8 11.8 4e-05 23.8 11.8 3.6 3 1 0 3 3 3 1 Trypsin Inhibitor like cysteine rich domain Tme5_EGF_like PF09064.10 CBY39196.1 - 0.023 14.6 4.1 0.039 13.9 1.4 3.0 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like TILa PF12714.7 CBY39196.1 - 0.077 13.0 0.1 0.077 13.0 0.1 4.6 2 1 2 4 4 4 0 TILa domain Neur_chan_memb PF02932.16 CBY39197.1 - 9.1e-37 127.4 5.8 2.9e-28 99.5 4.0 2.0 1 1 1 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Orai-1 PF07856.12 CBY39197.1 - 2.4 7.8 6.9 15 5.2 0.3 2.4 2 0 0 2 2 2 0 Mediator of CRAC channel activity PalH PF08733.10 CBY39197.1 - 6 5.8 6.8 0.54 9.2 1.3 1.8 2 0 0 2 2 2 0 PalH/RIM21 ABC2_membrane_5 PF13346.6 CBY39197.1 - 9 5.8 12.9 0.28 10.7 6.9 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4169 PF13770.6 CBY39198.1 - 0.34 11.2 1.9 3.7 7.9 1.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4169) Ephrin_rec_like PF07699.13 CBY39199.1 - 1.4e-07 31.2 364.0 0.00025 20.7 6.0 36.4 28 9 11 40 40 40 20 Putative ephrin-receptor like SBDS_C PF09377.10 CBY39199.1 - 0.091 12.8 0.1 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 SBDS protein C-terminal domain DNA_gyraseB_C PF00986.21 CBY39199.1 - 0.27 11.4 0.2 0.54 10.5 0.2 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Phosphorylase PF00343.20 CBY39200.1 - 1.7e-284 945.6 0.0 2e-284 945.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GldM_N PF12081.8 CBY39200.1 - 0.015 15.4 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 GldM N-terminal domain DUF3417 PF11897.8 CBY39200.1 - 0.093 13.2 1.9 17 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) LUC7 PF03194.15 CBY39201.1 - 2.8e-87 292.5 9.3 2.8e-87 292.5 9.3 2.1 2 1 0 2 2 2 1 LUC7 N_terminus AKAP95 PF04988.12 CBY39201.1 - 0.061 13.5 3.6 0.066 13.4 0.2 2.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Nucleoporin_FG PF13634.6 CBY39202.1 - 1.6e-21 77.0 107.2 5.1e-10 40.1 20.5 10.9 5 3 4 10 10 10 5 Nucleoporin FG repeat region Pam17 PF08566.10 CBY39203.1 - 0.052 13.4 1.2 8 6.3 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 zf-H2C2_2 PF13465.6 CBY39204.1 - 5.4e-20 70.9 21.8 1.1e-09 38.2 1.3 4.7 4 1 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY39204.1 - 1.1e-15 57.1 33.2 7.6e-06 26.1 1.7 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY39204.1 - 1.1e-09 38.3 33.8 4.1e-05 24.1 0.9 5.0 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBY39204.1 - 4.3e-05 24.2 18.2 0.084 13.6 4.8 3.3 2 1 1 3 3 3 3 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CBY39204.1 - 0.00034 20.5 17.0 0.045 13.8 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CBY39204.1 - 0.0023 18.0 16.1 1.8 8.8 0.9 4.5 4 0 0 4 4 4 2 Zinc ribbon domain zf_UBZ PF18439.1 CBY39204.1 - 0.007 15.9 12.7 0.3 10.7 2.0 4.3 4 0 0 4 4 4 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CBY39204.1 - 0.007 16.6 7.4 0.051 13.9 0.5 4.2 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CBY39204.1 - 0.2 11.5 0.1 0.2 11.5 0.1 4.7 5 0 0 5 5 4 0 C2H2-type zinc-finger domain zf-met PF12874.7 CBY39204.1 - 0.44 11.0 27.8 0.49 10.9 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.18 CBY39204.1 - 1.1 9.4 12.8 3.6 7.7 0.4 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zinc_ribbon_15 PF17032.5 CBY39204.1 - 2.6 8.9 15.6 1 10.2 3.6 3.0 1 1 2 3 3 3 0 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 CBY39204.1 - 2.7 8.0 11.3 4.8 7.2 2.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_11 PF16622.5 CBY39204.1 - 3 7.7 23.6 0.66 9.8 0.8 4.3 5 0 0 5 5 5 0 zinc-finger C2H2-type Prok-RING_1 PF14446.6 CBY39204.1 - 3.7 7.5 18.0 7.1 6.6 0.5 4.5 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 zf-MYST PF17772.1 CBY39204.1 - 3.8 7.2 14.3 1.6 8.4 0.4 4.2 5 0 0 5 5 5 0 MYST family zinc finger domain zinc_ribbon_9 PF14369.6 CBY39204.1 - 4.2 7.7 5.9 23 5.3 0.0 3.1 4 0 0 4 4 3 0 zinc-ribbon zf-C2HE PF16278.5 CBY39204.1 - 5.6 7.5 20.5 0.84 10.1 1.3 4.0 2 2 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 CBY39204.1 - 6.7 6.7 11.7 9.8 6.2 0.1 4.0 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.12 CBY39204.1 - 9 6.7 19.1 1.2 9.5 3.7 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Romo1 PF10247.9 CBY39205.1 - 0.82 10.1 14.1 0.14 12.6 3.7 2.2 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.6 CBY39205.1 - 0.83 9.7 23.0 1.4 9.0 22.4 1.8 1 1 0 1 1 1 0 Glycine zipper Peptidase_C1 PF00112.23 CBY39206.1 - 4.6e-16 59.6 0.0 4.6e-16 59.6 0.0 2.7 2 1 0 2 2 2 1 Papain family cysteine protease TSP_1 PF00090.19 CBY39206.1 - 0.003 17.7 19.5 0.003 17.7 19.5 3.0 2 0 0 2 2 2 1 Thrombospondin type 1 domain Somatomedin_B PF01033.17 CBY39206.1 - 0.014 15.8 21.0 0.014 15.8 21.0 5.9 6 2 0 6 6 6 0 Somatomedin B domain Laminin_EGF PF00053.24 CBY39207.1 - 0.029 14.5 15.7 0.063 13.4 15.7 1.5 1 0 0 1 1 1 0 Laminin EGF domain LRR_4 PF12799.7 CBY39209.1 - 1.6e-14 53.7 9.5 4.4e-05 23.7 0.1 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY39209.1 - 5.3e-13 48.8 5.6 8.4e-06 25.4 2.7 2.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBY39209.1 - 3.1e-07 30.1 10.4 0.0072 16.1 0.1 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBY39209.1 - 0.12 12.5 5.3 8.5 6.7 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CBY39209.1 - 0.2 12.3 6.2 87 4.3 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat EGF_CA PF07645.15 CBY39210.1 - 3.7e-25 87.8 39.9 6.7e-10 39.0 8.4 4.6 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CBY39210.1 - 3.6e-07 30.0 27.2 0.00017 21.4 2.1 4.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY39210.1 - 0.096 12.9 33.6 0.39 10.9 6.3 4.3 4 0 0 4 4 4 0 EGF domain GBP_PSP PF02425.15 CBY39210.1 - 0.54 9.9 11.3 3.1 7.5 0.1 4.4 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Vanabin-2 PF11437.8 CBY39210.1 - 2.7 8.2 34.1 1.2 9.3 4.9 3.6 1 1 2 3 3 3 0 Vanadium-binding protein 2 TIL PF01826.17 CBY39210.1 - 3.5 8.0 37.6 0.69 10.2 4.2 4.5 4 0 0 4 4 4 0 Trypsin Inhibitor like cysteine rich domain Sulfotransfer_2 PF03567.14 CBY39211.1 - 2.3e-18 67.0 1.3 3.6e-18 66.4 1.3 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY39211.1 - 0.0098 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY39211.1 - 0.13 12.6 0.0 0.71 10.2 0.0 1.8 1 1 1 2 2 2 0 Sulfotransferase family Sulfate_transp PF00916.20 CBY39212.1 - 8.5e-36 123.5 5.9 1.7e-35 122.5 5.9 1.4 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 CBY39212.1 - 0.67 10.4 11.9 0.075 13.4 7.5 1.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily ALMT PF11744.8 CBY39213.1 - 2.4 6.9 5.5 3.9 6.2 5.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Coatomer_b_Cpla PF14806.6 CBY39214.1 - 0.081 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform APH PF01636.23 CBY39215.1 - 7.7e-07 29.3 0.2 1e-06 28.9 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY39215.1 - 0.001 18.7 0.4 0.0014 18.2 0.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CBY39215.1 - 0.011 15.1 0.4 0.013 14.8 0.4 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Tmem26 PF09772.9 CBY39217.1 - 7.3e-74 248.7 3.8 7.6e-54 183.0 0.6 2.0 2 0 0 2 2 2 2 Transmembrane protein 26 Pkinase_Tyr PF07714.17 CBY39218.1 - 7.5e-64 215.5 0.0 1.1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY39218.1 - 7.8e-34 117.2 0.0 1.2e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY39218.1 - 0.0053 15.7 0.3 0.0053 15.7 0.3 2.4 2 1 1 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 CBY39218.1 - 0.098 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kelch_1 PF01344.25 CBY39219.1 - 1.6e-09 37.2 0.0 0.0032 17.0 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY39219.1 - 1.3e-06 28.5 0.4 0.026 14.8 0.0 3.6 2 2 1 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CBY39219.1 - 0.00014 21.8 0.1 0.049 13.6 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY39219.1 - 0.015 15.3 0.4 0.46 10.5 0.1 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY39219.1 - 0.046 13.7 0.1 4.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Kelch motif zf-C4 PF00105.18 CBY39222.1 - 7.2e-23 80.8 12.1 1.1e-22 80.2 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RING_4 PF14570.6 CBY39222.1 - 0.74 9.7 7.1 2.3 8.1 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY39222.1 - 3.9 7.9 11.1 5.2 7.5 8.4 2.2 1 1 1 2 2 2 0 Ring finger domain Thyroglobulin_1 PF00086.18 CBY39223.1 - 4.3e-05 23.1 0.9 4.3e-05 23.1 0.9 3.2 3 0 0 3 3 3 1 Thyroglobulin type-1 repeat SPARC_Ca_bdg PF10591.9 CBY39223.1 - 0.0039 17.5 2.7 3.5 8.0 0.7 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Cys_rich_CWC PF14375.6 CBY39223.1 - 0.35 11.3 3.5 18 5.9 0.9 3.0 2 0 0 2 2 2 0 Cysteine-rich CWC HECT PF00632.25 CBY39224.1 - 3.8e-79 266.3 0.0 5.7e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3337 PF11816.8 CBY39224.1 - 0.0091 15.9 0.1 0.16 11.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) GYF_2 PF14237.6 CBY39225.1 - 3.4e-13 49.2 0.2 9.3e-13 47.8 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 CBY39225.1 - 1.7e-11 44.1 0.3 5.3e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.23 CBY39225.1 - 7.2e-05 22.7 11.6 0.043 13.9 0.3 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Sec3-PIP2_bind PF15277.6 CBY39225.1 - 0.00075 19.6 0.2 0.16 12.1 0.3 3.0 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH KIAA1430 PF13879.6 CBY39225.1 - 1.6 9.5 4.1 1.2 9.9 0.5 2.5 2 0 0 2 2 2 0 KIAA1430 homologue DEAD PF00270.29 CBY39229.1 - 3.3e-37 128.0 0.4 5.2e-37 127.3 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY39229.1 - 6.3e-12 45.8 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY39229.1 - 1.9e-05 24.7 0.0 4.2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBY39229.1 - 0.0042 16.4 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 CBY39229.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF5548 PF17702.1 CBY39230.1 - 0.0044 16.8 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5548) HMG_box PF00505.19 CBY39233.1 - 1e-23 83.5 4.0 1.8e-23 82.7 4.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY39233.1 - 5.2e-12 46.2 2.3 1e-11 45.2 2.3 1.5 1 0 0 1 1 1 1 HMG-box domain RIB43A PF05914.12 CBY39233.1 - 0.004 16.0 0.5 0.004 16.0 0.5 1.5 2 0 0 2 2 2 1 RIB43A MlaC PF05494.12 CBY39233.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 MlaC protein IclR PF01614.18 CBY39234.1 - 0.13 12.1 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional regulator DUF919 PF06034.11 CBY39234.1 - 0.18 11.6 1.1 1.4 8.9 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Pro_isomerase PF00160.21 CBY39236.1 - 8.6e-50 169.1 1.0 7.5e-49 166.0 0.1 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CBY39236.1 - 1.5e-05 24.5 2.1 1.5e-05 24.5 2.1 2.1 2 1 0 2 2 2 1 Rtf2 RING-finger DUF4464 PF14713.6 CBY39237.1 - 2.9e-86 288.7 0.4 3.2e-86 288.5 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF5624 PF18538.1 CBY39237.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) 4F5 PF04419.14 CBY39238.1 - 2.7e-08 34.5 18.0 3.7e-08 34.1 18.0 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 CBY39238.1 - 0.00013 22.3 0.6 0.0002 21.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY39238.1 - 0.0072 16.6 1.4 0.012 15.9 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY39238.1 - 0.019 15.3 1.0 0.022 15.1 1.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Myb_DNA-binding PF00249.31 CBY39239.1 - 1.5e-08 34.7 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FYVE_2 PF02318.16 CBY39239.1 - 0.0011 19.2 1.0 0.0018 18.5 1.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger HBB PF06777.11 CBY39239.1 - 0.033 13.9 1.3 2.4 7.8 0.5 2.9 2 1 1 3 3 3 0 Helical and beta-bridge domain Myb_DNA-bind_6 PF13921.6 CBY39239.1 - 0.038 14.2 0.1 0.085 13.1 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2452 PF10504.9 CBY39239.1 - 0.077 12.5 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) FapA PF03961.13 CBY39239.1 - 0.094 11.3 2.7 0.12 11.0 2.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-RING_2 PF13639.6 CBY39239.1 - 6.4 7.2 9.4 3.2 8.2 7.3 1.6 2 0 0 2 2 2 0 Ring finger domain Kinesin PF00225.23 CBY39240.1 - 1.3e-89 300.4 0.5 1.3e-89 300.4 0.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY39240.1 - 6e-17 62.0 0.4 3.5e-16 59.5 0.3 2.2 2 0 0 2 2 2 1 Microtubule binding PAP1 PF08601.10 CBY39241.1 - 0.0082 15.9 0.6 0.01 15.6 0.6 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 SAS4 PF15460.6 CBY39241.1 - 0.097 12.8 1.7 0.15 12.2 0.5 1.8 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 PRD PF00874.20 CBY39241.1 - 0.16 12.3 0.7 0.53 10.6 0.3 1.9 1 1 1 2 2 2 0 PRD domain Glycolytic PF00274.19 CBY39243.1 - 4.1e-40 137.6 0.1 4.6e-40 137.4 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ECH_1 PF00378.20 CBY39244.1 - 1e-24 87.2 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY39244.1 - 0.00054 19.6 0.0 0.00089 18.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBY39244.1 - 0.0011 18.9 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 2 Peptidase family S49 CC PF04942.14 CBY39244.1 - 0.087 13.0 0.5 0.16 12.2 0.5 1.3 1 0 0 1 1 1 0 CC domain AIM3 PF17096.5 CBY39245.1 - 0.87 10.6 4.5 40 5.2 4.5 4.3 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 EF-hand_1 PF00036.32 CBY39246.1 - 0.00027 20.2 8.4 0.85 9.3 0.0 4.6 3 1 1 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY39246.1 - 0.00041 20.1 6.7 0.59 10.2 0.3 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY39246.1 - 0.03 14.2 4.3 0.68 9.8 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 CBY39246.1 - 0.033 14.6 14.4 0.065 13.7 1.3 3.5 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 CBY39246.1 - 1 9.0 8.0 4.6 6.9 0.0 3.6 3 0 0 3 3 3 0 EF hand Lyase_aromatic PF00221.19 CBY39247.1 - 1.2e-174 581.4 0.2 1.3e-174 581.2 0.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Neur_chan_memb PF02932.16 CBY39248.1 - 1.4e-29 103.9 0.6 1.7e-29 103.6 0.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region COX2-transmemb PF09125.10 CBY39248.1 - 0.037 13.8 1.1 0.1 12.4 1.1 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane MgtE PF01769.16 CBY39248.1 - 6.5 7.2 8.9 3.7 7.9 6.7 1.8 1 1 0 1 1 1 0 Divalent cation transporter Pkinase PF00069.25 CBY39250.1 - 3.2e-08 33.3 0.7 3.2e-08 33.3 0.7 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39250.1 - 0.00012 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Golgin_A5 PF09787.9 CBY39254.1 - 9.5 5.6 60.8 0.24 10.8 3.4 4.3 1 1 3 4 4 4 0 Golgin subfamily A member 5 Gal-3-0_sulfotr PF06990.11 CBY39255.1 - 6.3e-35 120.8 0.3 7e-34 117.4 0.3 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY39255.1 - 1.9e-05 24.7 3.6 5.3e-05 23.3 0.5 3.1 2 1 0 2 2 2 1 Sulfotransferase family Pet100 PF09803.9 CBY39255.1 - 0.16 12.5 2.4 0.33 11.5 0.4 2.6 2 0 0 2 2 2 0 Pet100 Sugar_tr PF00083.24 CBY39256.1 - 4.3e-109 365.4 20.0 2.5e-83 280.4 9.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBY39256.1 - 6.3e-30 104.3 33.1 2.7e-26 92.4 18.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 CBY39256.1 - 0.16 11.8 3.8 0.39 10.5 0.1 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4322 PF14210.6 CBY39256.1 - 0.2 11.6 0.0 0.56 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) CDV3 PF15359.6 CBY39257.1 - 0.62 10.6 8.4 0.13 12.7 4.7 1.9 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 ORC6 PF05460.13 CBY39259.1 - 0.35 10.1 12.3 0.51 9.6 12.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IL1_propep PF02394.16 CBY39259.1 - 0.37 11.7 2.4 1.8 9.5 0.5 2.5 2 0 0 2 2 2 0 Interleukin-1 propeptide UPF0016 PF01169.19 CBY39261.1 - 4.5e-21 75.0 9.9 5.6e-21 74.7 9.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 Mntp PF02659.15 CBY39261.1 - 4e-05 23.4 0.1 5.6e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Putative manganese efflux pump TerC PF03741.16 CBY39261.1 - 0.0069 16.1 0.1 0.0088 15.7 0.1 1.4 1 0 0 1 1 1 1 Integral membrane protein TerC family Phage_holin_3_6 PF07332.11 CBY39261.1 - 0.0099 15.9 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_U4 PF03419.13 CBY39261.1 - 0.015 14.6 0.4 0.019 14.3 0.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA FixQ PF05545.11 CBY39261.1 - 0.034 14.1 0.3 0.034 14.1 0.3 2.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF4094 PF13334.6 CBY39261.1 - 0.087 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) UPF0016 PF01169.19 CBY39262.1 - 7.3e-19 67.9 5.3 1e-18 67.4 5.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 Pyr_redox_2 PF07992.14 CBY39263.1 - 1.2e-65 221.7 8.9 2.4e-65 220.7 5.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBY39263.1 - 5.3e-41 139.3 2.0 5.3e-41 139.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBY39263.1 - 2.8e-20 72.6 7.9 1.2e-18 67.5 1.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBY39263.1 - 5.3e-09 35.9 0.3 5.3e-09 35.9 0.3 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY39263.1 - 1.6e-07 30.9 5.3 0.00064 19.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY39263.1 - 9.4e-07 28.2 0.3 9.4e-07 28.2 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBY39263.1 - 1.5e-06 28.3 4.8 3e-05 24.2 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY39263.1 - 2.7e-06 26.7 0.9 2.7e-06 26.7 0.9 2.9 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CBY39263.1 - 3.8e-06 25.9 10.9 0.002 16.9 0.9 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 CBY39263.1 - 4.9e-06 26.4 10.2 0.0043 16.7 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CBY39263.1 - 0.00013 21.3 0.5 0.068 12.3 0.1 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 CBY39263.1 - 0.00016 20.4 1.0 0.00033 19.4 0.3 1.7 1 1 1 2 2 2 1 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 CBY39263.1 - 0.0023 17.2 6.1 0.26 10.6 0.2 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBY39263.1 - 0.0028 17.0 2.3 0.017 14.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBY39263.1 - 0.019 14.2 11.4 0.15 11.3 0.5 3.5 4 0 0 4 4 4 0 FAD binding domain Amino_oxidase PF01593.24 CBY39263.1 - 0.18 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 CBY39263.1 - 0.51 9.9 5.3 9.2 5.8 0.2 3.6 4 0 0 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 CBY39263.1 - 3.5 6.6 5.8 2.4 7.1 0.4 2.8 3 1 1 4 4 4 0 Lycopene cyclase protein Zona_pellucida PF00100.23 CBY39264.1 - 0.0047 16.8 1.1 0.0056 16.5 1.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain Cu2_monoox_C PF03712.15 CBY39266.1 - 3.5e-13 49.3 1.5 5.4e-13 48.7 1.5 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Trypan_PARP PF05887.11 CBY39266.1 - 0.1 12.6 2.2 0.19 11.7 2.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Collagen PF01391.18 CBY39267.1 - 5.3e-76 250.3 232.3 2.8e-09 36.6 23.3 10.3 1 1 5 6 6 6 4 Collagen triple helix repeat (20 copies) zf-RING_2 PF13639.6 CBY39268.1 - 5.4e-10 39.4 8.1 1.1e-09 38.5 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY39268.1 - 7.6e-08 32.1 6.6 1.7e-07 30.9 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY39268.1 - 2e-07 31.0 1.1 4.6e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY39268.1 - 4.7e-07 29.6 8.9 1.2e-06 28.2 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY39268.1 - 1.2e-06 28.5 4.3 2e-06 27.7 3.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY39268.1 - 3.2e-06 27.3 6.6 8.5e-06 26.0 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CBY39268.1 - 1.7e-05 24.5 7.1 3.3e-05 23.6 7.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CBY39268.1 - 1.8e-05 24.6 8.9 1.8e-05 24.6 8.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBY39268.1 - 4.9e-05 23.4 3.7 4.9e-05 23.4 3.7 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY39268.1 - 0.00011 21.9 8.0 0.00029 20.6 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY39268.1 - 0.00032 20.5 5.8 0.00075 19.3 5.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY39268.1 - 0.0084 16.0 1.3 0.02 14.7 1.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein WD40_alt PF14077.6 CBY39268.1 - 0.056 13.3 0.2 0.056 13.3 0.2 3.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif Zn_ribbon_17 PF17120.5 CBY39268.1 - 0.088 12.4 6.8 0.19 11.4 6.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ADIP PF11559.8 CBY39268.1 - 0.37 10.9 35.4 1.9 8.6 11.5 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DZR PF12773.7 CBY39268.1 - 0.8 9.8 8.0 3.4 7.7 8.1 2.0 1 1 1 2 2 2 0 Double zinc ribbon Leuk-A4-hydro_C PF09127.11 CBY39268.1 - 1.5 8.9 6.1 1.1 9.4 0.2 3.4 4 1 0 4 4 4 0 Leukotriene A4 hydrolase, C-terminal IBR PF01485.21 CBY39268.1 - 1.9 8.8 10.8 32 4.9 11.1 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 CBY39268.1 - 3 8.0 5.5 7.8 6.7 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FYVE PF01363.21 CBY39268.1 - 3.4 7.9 9.6 2.6 8.2 7.3 2.0 2 0 0 2 2 1 0 FYVE zinc finger zf-RING_10 PF16685.5 CBY39268.1 - 9.1 6.5 9.1 3.5 7.8 5.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 PikAIV_N PF18605.1 CBY39270.1 - 0.34 10.5 7.1 0.1 12.2 2.1 2.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Rootletin PF15035.6 CBY39271.1 - 0.012 15.6 10.4 0.014 15.4 10.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SPATA1_C PF15743.5 CBY39271.1 - 0.024 14.7 8.8 0.034 14.2 8.8 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus DUF3201 PF11447.8 CBY39271.1 - 0.042 13.4 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) Tweety PF04906.13 CBY39271.1 - 0.094 11.4 1.4 0.1 11.2 1.4 1.0 1 0 0 1 1 1 0 Tweety DUF4337 PF14235.6 CBY39271.1 - 0.11 12.6 1.1 0.13 12.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.22 CBY39271.1 - 0.16 12.2 8.8 0.22 11.8 8.8 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CBY39271.1 - 0.16 12.5 12.9 0.19 12.3 12.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 CBY39271.1 - 0.16 12.0 2.6 0.2 11.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cep57_CLD_2 PF14197.6 CBY39271.1 - 0.22 11.6 13.6 12 6.0 15.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 FapA PF03961.13 CBY39271.1 - 0.24 10.0 6.0 0.25 9.9 6.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Bcr-Abl_Oligo PF09036.10 CBY39271.1 - 0.49 10.4 5.3 3.5 7.7 3.0 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DASH_Hsk3 PF08227.11 CBY39271.1 - 0.64 10.4 6.7 14 6.1 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Csm1_N PF18504.1 CBY39271.1 - 2 8.8 12.2 13 6.2 9.8 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 CBY39271.1 - 2.9 8.4 16.9 76 3.9 16.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB Fmp27_WPPW PF10359.9 CBY39271.1 - 4 6.2 7.6 4.8 5.9 7.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HALZ PF02183.18 CBY39271.1 - 5.1 7.4 15.2 10 6.4 3.1 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 CBY39271.1 - 5.1 7.8 8.8 9.1 7.0 8.2 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Helo_like_N PF17111.5 CBY39272.1 - 0.0081 15.6 1.6 0.01 15.2 1.6 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins bZIP_1 PF00170.21 CBY39272.1 - 0.061 13.4 8.0 0.24 11.5 3.2 2.2 1 1 1 2 2 2 0 bZIP transcription factor Phlebovirus_G1 PF07243.11 CBY39272.1 - 0.1 10.9 1.1 0.14 10.6 1.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Seryl_tRNA_N PF02403.22 CBY39272.1 - 0.64 10.3 6.9 0.7 10.1 5.3 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 CBY39272.1 - 1.3 9.5 9.0 10 6.6 9.0 2.1 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 CBY39272.1 - 8.1 6.6 9.3 1.1 9.4 2.8 2.5 1 1 2 3 3 3 0 Basic region leucine zipper Cadherin PF00028.17 CBY39273.1 - 4.5e-49 164.8 6.1 3.6e-13 49.8 0.0 7.0 7 0 0 7 7 7 6 Cadherin domain Cadherin_2 PF08266.12 CBY39273.1 - 1.9e-06 27.6 0.6 0.0095 15.8 0.1 4.2 3 1 0 3 3 3 1 Cadherin-like Shisa PF13908.6 CBY39273.1 - 0.012 15.9 0.4 0.083 13.1 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mucin PF01456.17 CBY39273.1 - 0.014 15.4 0.3 0.031 14.3 0.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Comm PF15957.5 CBY39273.1 - 0.031 14.6 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Commissureless EphA2_TM PF14575.6 CBY39273.1 - 0.038 14.9 0.0 0.084 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 CBY39273.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.15 CBY39273.1 - 0.18 11.6 3.2 0.41 10.5 3.2 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cadherin_C_2 PF16492.5 CBY39273.1 - 0.18 12.6 0.0 2.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Mlh1_C PF16413.5 CBY39274.1 - 2.1e-44 151.9 7.7 6.1e-44 150.4 3.4 2.9 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CBY39274.1 - 4.7e-27 94.0 1.0 1.3e-26 92.7 0.1 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Lectin_legB PF00139.19 CBY39274.1 - 0.011 15.3 0.2 0.022 14.3 0.1 1.6 1 1 0 1 1 1 0 Legume lectin domain HATPase_c_3 PF13589.6 CBY39275.1 - 5.1e-17 62.0 0.1 6.6e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBY39275.1 - 3.3e-09 37.2 0.0 4.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCDC50_N PF15295.6 CBY39276.1 - 2.8e-34 118.0 13.3 2.8e-34 118.0 13.3 4.8 3 1 1 4 4 4 2 Coiled-coil domain-containing protein 50 N-terminus ACAS_N PF16177.5 CBY39277.1 - 1.5e-09 37.6 0.4 2.1e-09 37.1 0.4 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AKAP95 PF04988.12 CBY39278.1 - 0.0098 16.1 5.6 0.0098 16.1 5.6 2.7 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 CBY39278.1 - 0.012 15.9 1.8 0.012 15.9 1.8 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY39278.1 - 0.05 14.4 1.3 0.35 11.8 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1612 PF07756.12 CBY39278.1 - 0.075 13.3 0.6 0.15 12.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) zf-met PF12874.7 CBY39278.1 - 0.23 11.9 0.6 0.88 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY39278.1 - 0.28 11.7 1.7 0.82 10.3 1.2 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY39278.1 - 0.33 11.3 2.9 0.81 10.1 2.8 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NHL PF01436.21 CBY39279.1 - 2.6e-08 33.5 1.3 0.00024 21.0 0.0 3.7 3 0 0 3 3 3 2 NHL repeat DUF5128 PF17170.4 CBY39279.1 - 0.012 14.8 0.5 0.025 13.7 0.5 1.5 1 0 0 1 1 1 0 6-bladed beta-propeller Phytase-like PF13449.6 CBY39279.1 - 0.072 13.0 0.0 0.57 10.1 0.0 2.0 1 1 0 2 2 2 0 Esterase-like activity of phytase SGL PF08450.12 CBY39279.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Glyco_hydro_30 PF02055.16 CBY39280.1 - 6.5e-94 314.8 0.6 7.7e-94 314.5 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Redoxin PF08534.10 CBY39280.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Redoxin MerR_1 PF13411.6 CBY39280.1 - 0.12 12.5 0.0 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein LRR_4 PF12799.7 CBY39282.1 - 1.5e-19 69.7 29.8 1.8e-06 28.1 2.2 6.4 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY39282.1 - 1.3e-15 57.4 13.5 1.1e-11 44.6 0.3 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBY39282.1 - 9.7e-15 54.1 27.7 9.2e-07 28.5 4.1 5.1 4 1 1 5 5 5 4 Leucine rich repeat Terminase_2 PF03592.16 CBY39282.1 - 0.02 15.3 0.1 0.049 14.1 0.1 1.6 1 0 0 1 1 1 0 Terminase small subunit FRP PF18032.1 CBY39282.1 - 0.11 13.2 2.1 0.47 11.1 0.0 2.9 2 1 1 3 3 3 0 Photoprotection regulator fluorescence recovery protein LRR_6 PF13516.6 CBY39282.1 - 1.3 9.2 0.0 1.3 9.2 0.0 7.7 8 1 1 9 9 9 0 Leucine Rich repeat DUF596 PF04591.12 CBY39283.1 - 0.14 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF596 SAP PF02037.27 CBY39283.1 - 0.17 11.7 0.1 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 SAP domain PHD PF00628.29 CBY39284.1 - 4.6e-14 52.1 24.5 3.2e-07 30.1 10.7 2.4 2 0 0 2 2 2 2 PHD-finger Mtf2_C PF14061.6 CBY39284.1 - 5.9e-07 29.5 0.3 1.2e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 PHD_4 PF16866.5 CBY39284.1 - 0.0014 18.7 18.0 0.011 15.8 3.6 2.9 2 1 0 2 2 2 2 PHD-finger Tudor_2 PF18104.1 CBY39284.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain HypA PF01155.19 CBY39284.1 - 3.1 7.9 6.3 8.6 6.4 0.5 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DnaJ PF00226.31 CBY39285.1 - 1.3e-14 54.0 0.2 2.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SH3_9 PF14604.6 CBY39285.1 - 4.4e-09 36.1 0.0 8.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY39285.1 - 3.1e-08 33.1 0.1 5.8e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY39285.1 - 1.8e-06 27.5 0.0 2.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF3450 PF11932.8 CBY39285.1 - 0.0031 16.8 1.8 0.0054 16.1 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4201 PF13870.6 CBY39285.1 - 0.0068 16.2 1.7 0.013 15.2 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.7 CBY39285.1 - 0.014 15.6 1.4 0.024 14.8 1.4 1.3 1 0 0 1 1 1 0 Tropomyosin like Med9 PF07544.13 CBY39285.1 - 0.062 13.4 1.2 0.11 12.6 1.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FliD_N PF02465.18 CBY39285.1 - 0.088 13.5 2.3 0.43 11.3 1.3 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DASH_Dam1 PF08653.10 CBY39285.1 - 0.11 12.4 0.4 0.24 11.2 0.4 1.6 1 0 0 1 1 1 0 DASH complex subunit Dam1 DASH_Dad4 PF08650.10 CBY39285.1 - 0.12 12.4 1.8 0.32 11.0 1.8 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad4 Lectin_N PF03954.14 CBY39285.1 - 0.41 10.4 2.5 0.76 9.5 2.5 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain YabA PF06156.13 CBY39285.1 - 1.2 9.8 3.1 0.69 10.6 1.1 1.7 2 0 0 2 2 2 0 Initiation control protein YabA PI3K_P85_iSH2 PF16454.5 CBY39285.1 - 3.2 7.3 7.2 0.36 10.4 2.0 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAD_binding_3 PF01494.19 CBY39286.1 - 4e-20 72.4 0.0 9.9e-20 71.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY39286.1 - 9e-06 25.1 1.2 0.016 14.5 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY39286.1 - 9.6e-05 22.5 0.4 0.0004 20.5 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBY39286.1 - 0.00017 20.8 0.2 0.00028 20.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBY39286.1 - 0.00071 19.3 0.1 0.74 9.3 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 CBY39286.1 - 0.00085 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.14 CBY39286.1 - 0.015 14.0 1.4 0.058 12.1 1.4 1.9 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CBY39286.1 - 0.037 13.3 1.7 2.5 7.3 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBY39286.1 - 0.066 12.3 0.8 0.1 11.7 0.8 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CBY39286.1 - 0.17 11.9 0.1 10 6.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2116 PF09889.9 CBY39287.1 - 0.14 12.1 0.5 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Antistasin PF02822.14 CBY39287.1 - 4.5 8.0 6.0 47 4.7 3.6 3.0 2 1 0 2 2 2 0 Antistasin family A_deamin PF02137.18 CBY39288.1 - 1.5e-94 317.2 0.0 2.2e-94 316.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain dsrm PF00035.26 CBY39288.1 - 3.2e-08 34.2 0.0 0.014 16.1 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Abhydrolase_1 PF00561.20 CBY39289.1 - 1.4e-12 47.8 0.4 4.2e-10 39.7 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBY39289.1 - 2.8e-12 46.4 0.0 5.3e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY39289.1 - 3.8e-08 34.2 0.0 6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY39289.1 - 0.0038 17.4 0.0 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 CBY39289.1 - 0.0049 15.9 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF829 PF05705.14 CBY39289.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) DUF1043 PF06295.12 CBY39290.1 - 0.013 15.5 0.5 0.024 14.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FadA PF09403.10 CBY39290.1 - 0.022 15.2 6.1 0.057 13.9 6.1 1.6 1 0 0 1 1 1 0 Adhesion protein FadA HECT_2 PF09814.9 CBY39291.1 - 7.1e-06 25.1 3.4 0.014 14.2 0.3 2.3 2 1 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Tudor_4 PF18358.1 CBY39291.1 - 0.14 11.8 0.0 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Ribosomal_S5 PF00333.20 CBY39292.1 - 2e-29 101.3 1.3 3.9e-29 100.4 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CBY39292.1 - 2.4e-26 91.0 0.0 3.8e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rcd1 PF04078.13 CBY39293.1 - 6.5e-21 74.8 0.1 7.6e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Gelsolin PF00626.22 CBY39293.1 - 0.0087 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat Ceramidase PF05875.12 CBY39295.1 - 4e-15 55.9 0.4 4.9e-15 55.7 0.4 1.1 1 0 0 1 1 1 1 Ceramidase Ceramidase PF05875.12 CBY39296.1 - 1.1e-18 67.6 6.3 1.1e-18 67.6 6.3 1.0 1 0 0 1 1 1 1 Ceramidase Lipocalin PF00061.23 CBY39297.1 - 2.2e-05 24.7 1.3 2.6e-05 24.4 1.3 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Rhamno_transf PF11316.8 CBY39297.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase U3_assoc_6 PF08640.11 CBY39298.1 - 0.043 13.9 2.4 0.29 11.2 1.9 2.4 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 SCAPER_N PF16501.5 CBY39298.1 - 0.053 13.5 4.7 0.055 13.5 2.7 2.1 1 1 1 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum DUF523 PF04463.12 CBY39298.1 - 0.097 12.7 1.1 0.26 11.3 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF523) DUF3510 PF12022.8 CBY39298.1 - 7.9 6.9 9.1 2.6 8.4 4.2 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF3510) ANAPC1 PF12859.7 CBY39299.1 - 0.11 13.1 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 SLC12 PF03522.15 CBY39300.1 - 1.5e-102 343.9 0.1 4.5e-72 243.4 0.1 2.1 1 1 1 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 CBY39300.1 - 8.6e-101 337.9 34.9 1e-100 337.6 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_N PF08403.10 CBY39300.1 - 1.1e-07 31.2 0.1 9.3e-07 28.3 0.1 2.3 2 0 0 2 2 2 1 Amino acid permease N-terminal FA_hydroxylase PF04116.13 CBY39300.1 - 0.85 10.0 4.6 1.1 9.7 1.7 2.7 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Helicase_C PF00271.31 CBY39301.1 - 5.6e-21 75.0 0.2 1.3e-20 73.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBY39301.1 - 0.00053 19.3 0.0 0.00093 18.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AdoHcyase PF05221.17 CBY39302.1 - 2e-94 316.1 0.0 5e-75 252.4 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBY39302.1 - 2.2e-37 128.7 0.7 4.1e-37 127.7 0.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBY39302.1 - 0.0025 17.2 0.1 0.005 16.2 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 CBY39302.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 CBY39302.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Tetraspanin PF00335.20 CBY39304.1 - 2.8e-21 76.3 1.9 2.8e-21 76.3 1.9 1.9 2 0 0 2 2 2 1 Tetraspanin family Ldl_recept_a PF00057.18 CBY39305.1 - 0.0096 16.1 4.9 0.0096 16.1 4.9 3.1 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A IL6Ra-bind PF09240.10 CBY39306.1 - 0.017 15.5 0.1 0.037 14.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding Rad52_Rad22 PF04098.15 CBY39306.1 - 0.063 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Pecanex_C PF05041.15 CBY39308.1 - 0.0013 18.4 0.9 0.0024 17.5 0.9 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Sec10 PF07393.11 CBY39309.1 - 1.7e-72 244.9 1.3 2e-72 244.7 1.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Phospholip_A2_1 PF00068.19 CBY39310.1 - 0.0033 17.9 1.2 0.0033 17.9 1.2 2.2 2 1 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY39311.1 - 1.4e-07 32.0 1.9 2.3e-07 31.3 1.9 1.4 1 0 0 1 1 1 1 Phospholipase A2 TPR_12 PF13424.6 CBY39312.1 - 5.3e-11 42.6 10.3 3.9e-06 27.1 0.1 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBY39312.1 - 5.8e-06 25.9 3.5 0.00033 20.1 1.2 2.4 2 0 0 2 2 2 2 MalT-like TPR region zf-RING_11 PF17123.5 CBY39312.1 - 0.00065 19.4 1.4 0.0015 18.2 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger Rapsyn_N PF10579.9 CBY39312.1 - 0.0033 17.5 0.2 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region SNAP PF14938.6 CBY39312.1 - 0.0079 15.6 6.6 0.0079 15.6 6.6 2.0 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP zf-RING_2 PF13639.6 CBY39312.1 - 0.011 16.1 7.0 0.032 14.6 7.0 1.9 1 0 0 1 1 1 0 Ring finger domain TPR_19 PF14559.6 CBY39312.1 - 0.034 14.6 5.4 0.42 11.2 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBY39312.1 - 0.038 14.1 5.9 0.81 9.8 1.2 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 CBY39312.1 - 0.039 14.6 0.1 8.9 7.3 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBY39312.1 - 0.12 13.0 3.0 2.3 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 CBY39312.1 - 0.13 12.2 3.4 0.46 10.4 3.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY39312.1 - 0.23 11.4 8.5 0.62 10.1 8.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_10 PF13374.6 CBY39312.1 - 0.27 11.2 4.6 11 6.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY39312.1 - 0.28 11.5 10.8 55 4.3 0.1 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY39312.1 - 1 9.6 6.5 8.1 6.7 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat YHYH PF14240.6 CBY39313.1 - 6.4e-21 75.2 2.9 7.3e-14 52.2 0.1 2.6 1 1 1 2 2 2 2 YHYH protein Anti-TRAP PF15777.5 CBY39313.1 - 0.08 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein TSP_1 PF00090.19 CBY39316.1 - 2e-10 40.7 39.8 3.1e-08 33.7 7.1 7.8 7 1 0 7 7 7 4 Thrombospondin type 1 domain ADAM_spacer1 PF05986.14 CBY39316.1 - 2.5e-05 24.3 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ADAM-TS Spacer 1 ADAM_CR_2 PF17771.1 CBY39316.1 - 0.00073 20.0 1.4 0.00073 20.0 1.4 7.0 5 2 1 7 7 7 2 ADAM cysteine-rich domain UPA PF17217.3 CBY39317.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 UPA domain ig PF00047.25 CBY39317.1 - 0.057 13.6 0.0 0.096 12.9 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin domain I-set PF07679.16 CBY39317.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ax_dynein_light PF10211.9 CBY39318.1 - 2.3e-06 27.7 6.2 2.3e-06 27.7 6.2 3.1 2 1 0 2 2 2 1 Axonemal dynein light chain RasGAP_C PF03836.15 CBY39318.1 - 0.026 14.7 3.5 2.1 8.5 1.1 3.2 3 0 0 3 3 3 0 RasGAP C-terminus V_ATPase_I PF01496.19 CBY39318.1 - 0.4 8.5 6.3 0.64 7.9 6.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CBY39319.1 - 0.11 11.6 14.2 0.13 11.3 14.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBY39319.1 - 0.18 11.3 12.4 0.21 11.1 12.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 CBY39319.1 - 0.57 9.9 12.4 0.91 9.3 12.4 1.3 1 0 0 1 1 1 0 AAA domain DUF4554 PF15091.6 CBY39319.1 - 0.68 8.8 10.2 0.82 8.5 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Amidase PF01425.21 CBY39319.1 - 1.1 8.2 4.8 1.4 7.8 4.8 1.1 1 0 0 1 1 1 0 Amidase Asp-B-Hydro_N PF05279.11 CBY39319.1 - 2.3 8.2 18.4 3 7.8 18.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CBY39319.1 - 2.5 6.8 11.6 2.9 6.6 11.6 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CBY39319.1 - 2.7 8.1 9.2 3.6 7.7 9.2 1.2 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 CBY39319.1 - 2.9 6.3 24.2 3.4 6.0 24.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 CBY39319.1 - 5.4 5.2 18.0 6.7 4.9 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2868 PF11067.8 CBY39319.1 - 6.2 6.2 7.4 9.1 5.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) AAA_11 PF13086.6 CBY39320.1 - 0.049 13.4 5.8 0.058 13.2 5.8 1.2 1 0 0 1 1 1 0 AAA domain AcetylCoA_hydro PF02550.15 CBY39320.1 - 0.21 11.6 1.6 0.3 11.0 1.6 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Membralin PF09746.9 CBY39320.1 - 4.5 6.2 6.7 5.5 5.9 6.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.6 CBY39320.1 - 4.8 6.5 12.3 6.3 6.1 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pneumo_M2 PF07380.11 CBY39321.1 - 0.069 13.4 1.5 0.62 10.4 0.1 2.5 2 0 0 2 2 2 0 Pneumovirus M2 protein FAD-SLDH PF12318.8 CBY39321.1 - 0.32 11.0 5.3 3.1 7.9 0.1 2.7 1 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Mito_carr PF00153.27 CBY39322.1 - 1.7e-48 162.5 1.0 2.2e-15 56.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_98C PF08307.11 CBY39322.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Spc7 PF08317.11 CBY39326.1 - 0.0041 16.1 22.9 0.006 15.5 22.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein SHE3 PF17078.5 CBY39326.1 - 0.0082 15.9 19.7 0.011 15.4 19.7 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF2316 PF10078.9 CBY39326.1 - 0.0094 16.2 5.5 0.016 15.5 5.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) YlqD PF11068.8 CBY39326.1 - 0.04 14.3 14.4 0.033 14.5 13.3 1.4 1 1 0 1 1 1 0 YlqD protein TarH PF02203.15 CBY39326.1 - 0.046 13.6 4.5 0.05 13.5 4.0 1.4 1 1 0 1 1 1 0 Tar ligand binding domain homologue TMCO5 PF14992.6 CBY39326.1 - 0.055 13.0 21.4 0.07 12.7 21.4 1.1 1 0 0 1 1 1 0 TMCO5 family THP2 PF09432.10 CBY39326.1 - 0.23 11.5 11.7 2.6 8.1 6.3 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 FliJ PF02050.16 CBY39326.1 - 0.26 11.5 19.7 0.17 12.1 8.6 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4200 PF13863.6 CBY39326.1 - 0.33 11.4 28.5 1 9.8 8.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 CBY39326.1 - 0.37 11.1 17.4 0.17 12.2 12.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CBY39326.1 - 0.53 10.8 31.8 0.33 11.5 20.4 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 CBY39326.1 - 0.81 8.7 20.2 1 8.4 20.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CBY39326.1 - 1.5 8.9 27.8 0.43 10.6 9.1 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY39326.1 - 1.6 8.7 7.2 1.7 8.7 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3391 PF11871.8 CBY39326.1 - 2.8 8.5 9.3 0.67 10.5 5.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) FliD_N PF02465.18 CBY39326.1 - 3.2 8.5 12.4 0.66 10.7 6.8 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Prefoldin_2 PF01920.20 CBY39326.1 - 3.7 7.5 24.3 0.78 9.7 10.6 2.9 1 1 2 3 3 3 0 Prefoldin subunit CorA PF01544.18 CBY39326.1 - 3.9 6.7 11.3 4.6 6.5 11.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S46 PF10459.9 CBY39326.1 - 4.1 5.9 10.6 4.8 5.7 10.6 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF501 PF04417.12 CBY39326.1 - 5.7 6.8 8.4 1.5 8.6 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF501) TMPIT PF07851.13 CBY39326.1 - 5.7 6.1 16.0 2.1 7.5 13.2 1.6 1 1 1 2 2 2 0 TMPIT-like protein DHR10 PF18595.1 CBY39326.1 - 6.6 6.8 27.3 17 5.5 19.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 CBY39326.1 - 7.6 7.2 18.0 17 6.1 0.4 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 CBY39326.1 - 7.6 6.0 15.7 8.9 5.8 15.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CBY39326.1 - 7.7 5.8 14.7 15 4.8 14.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CBY39326.1 - 10 4.9 13.1 12 4.6 13.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RBD-FIP PF09457.10 CBY39327.1 - 0.0012 18.7 0.7 0.0012 18.7 0.7 1.8 2 0 0 2 2 2 1 FIP domain ZapB PF06005.12 CBY39327.1 - 0.0041 17.5 3.2 0.028 14.9 3.2 2.0 1 1 0 1 1 1 1 Cell division protein ZapB Rx_N PF18052.1 CBY39327.1 - 0.0055 16.9 0.5 0.41 10.9 0.1 2.1 1 1 1 2 2 2 1 Rx N-terminal domain DUF4085 PF13315.6 CBY39327.1 - 0.0079 15.8 2.0 0.0094 15.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) Cnn_1N PF07989.11 CBY39327.1 - 0.012 15.8 2.6 0.073 13.2 0.5 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FlaC_arch PF05377.11 CBY39327.1 - 0.015 15.6 1.5 5.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 CBY39327.1 - 0.019 15.2 1.5 0.98 9.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF842 PF05811.13 CBY39327.1 - 0.15 11.8 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pox_A_type_inc PF04508.12 CBY39327.1 - 0.27 11.1 0.5 0.27 11.1 0.5 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Lge1 PF11488.8 CBY39327.1 - 0.74 10.0 5.3 9.6 6.5 0.5 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 EF-hand_6 PF13405.6 CBY39328.1 - 4.7e-08 32.3 3.5 0.0014 18.4 0.1 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBY39328.1 - 5.7e-08 31.8 1.2 0.0093 15.5 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY39328.1 - 2e-06 28.1 5.5 0.025 15.0 1.2 3.1 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY39328.1 - 2.6e-05 23.5 5.2 0.0078 15.7 0.2 3.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CBY39328.1 - 0.00052 19.8 4.0 0.11 12.4 1.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair SAM_2 PF07647.17 CBY39329.1 - 0.00052 20.1 0.1 0.00087 19.4 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CBY39329.1 - 0.0014 19.0 0.1 0.002 18.5 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUFIP1 PF10453.9 CBY39329.1 - 0.05 13.5 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Lyase_1 PF00206.20 CBY39331.1 - 5.6e-24 85.1 0.0 8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CBY39331.1 - 1.3e-05 25.6 0.0 4.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus FtsK_alpha PF17854.1 CBY39332.1 - 0.068 13.3 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsK alpha domain Ribosomal_L11_N PF03946.14 CBY39335.1 - 2.5e-22 78.5 0.2 3.8e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBY39335.1 - 2.1e-15 57.0 0.2 3e-15 56.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SNARE PF05739.19 CBY39336.1 - 1.4e-16 60.2 4.9 4.5e-16 58.6 3.7 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CBY39336.1 - 3.6e-16 59.4 7.9 3.6e-16 59.4 7.9 2.3 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 CBY39336.1 - 1.1e-08 34.9 13.8 1.1e-08 34.9 13.8 2.5 2 1 0 2 2 2 1 Syntaxin DUF4448 PF14610.6 CBY39336.1 - 0.048 13.4 1.7 0.073 12.8 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 CBY39336.1 - 0.076 11.8 6.5 0.091 11.5 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Enkurin PF13864.6 CBY39336.1 - 4 7.9 10.6 1.6 9.2 4.4 3.0 1 1 1 2 2 2 0 Calmodulin-binding PIN_8 PF18476.1 CBY39336.1 - 6.2 6.6 13.3 8.7 6.1 1.9 2.1 1 1 1 2 2 2 0 PIN like domain Complex1_LYR PF05347.15 CBY39337.1 - 0.00016 21.7 0.2 0.00023 21.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ING PF12998.7 CBY39337.1 - 0.066 13.8 2.1 0.15 12.7 2.1 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding YqeY PF09424.10 CBY39337.1 - 0.087 12.9 1.3 0.13 12.3 1.3 1.2 1 0 0 1 1 1 0 Yqey-like protein EF-hand_7 PF13499.6 CBY39338.1 - 2.1e-05 24.9 5.3 0.0042 17.5 0.4 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBY39338.1 - 2.6e-05 23.4 0.1 8.9e-05 21.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CBY39338.1 - 0.00015 21.1 0.0 0.00036 19.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY39338.1 - 0.00067 19.4 0.0 0.0024 17.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain E2F_TDP PF02319.20 CBY39339.1 - 0.091 12.8 0.0 0.42 10.7 0.0 2.1 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Peptidase_M13 PF01431.21 CBY39340.1 - 1.5e-52 178.2 1.4 2.4e-52 177.5 1.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 CBY39340.1 - 7.2e-23 81.9 0.1 1.4e-22 80.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 S_layer_N PF05123.12 CBY39340.1 - 0.0087 16.0 1.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 1 S-layer like family, N-terminal region SPECT1 PF18680.1 CBY39340.1 - 0.031 13.9 1.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 Pkinase PF00069.25 CBY39341.1 - 1.2e-56 192.0 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39341.1 - 1.7e-36 125.8 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39341.1 - 5.2e-09 35.8 0.0 9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY39341.1 - 4.1e-06 26.0 0.0 5.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY39341.1 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY39341.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Torsin PF06309.11 CBY39342.1 - 7e-28 97.3 0.0 1.4e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.14 CBY39342.1 - 0.0061 16.6 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBY39342.1 - 0.023 14.5 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 CBY39342.1 - 0.037 14.4 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CBY39342.1 - 0.061 13.4 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CBY39342.1 - 0.064 13.4 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 CBY39342.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CBY39342.1 - 0.15 12.3 0.0 0.96 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY39342.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain BolA PF01722.18 CBY39343.1 - 1.9e-15 56.9 0.1 1.5e-14 54.0 0.1 1.9 1 1 0 1 1 1 1 BolA-like protein SRP68 PF16969.5 CBY39344.1 - 2.7e-79 267.7 14.5 5.7e-77 260.0 14.5 2.2 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 MCM PF00493.23 CBY39345.1 - 1.4e-99 331.8 0.0 2.8e-99 330.8 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CBY39345.1 - 1.5e-33 115.3 1.0 1.5e-33 115.3 1.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_N PF14551.6 CBY39345.1 - 1.2e-17 64.4 0.3 2.6e-17 63.3 0.3 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY39345.1 - 2.3e-08 33.7 1.5 1e-05 25.0 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY39345.1 - 5.9e-07 29.6 0.0 2.4e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_lid PF17855.1 CBY39345.1 - 1.5e-05 25.3 0.3 3.4e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_bind PF09739.9 CBY39345.1 - 0.00066 18.3 0.2 0.0012 17.5 0.2 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_3 PF07726.11 CBY39345.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY39345.1 - 0.03 14.0 0.4 0.12 12.1 0.1 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain zf_UBZ PF18439.1 CBY39345.1 - 0.081 12.5 1.2 0.43 10.2 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LRR_4 PF12799.7 CBY39346.1 - 0.0095 16.3 0.1 0.013 15.9 0.1 1.2 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) NDK PF00334.19 CBY39347.1 - 7e-58 194.4 0.2 6e-29 100.8 0.1 2.0 1 1 1 2 2 2 2 Nucleoside diphosphate kinase BCMA-Tall_bind PF09257.10 CBY39347.1 - 0.13 12.4 0.1 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 BCMA, TALL-1 binding Pkinase PF00069.25 CBY39348.1 - 2.5e-32 112.3 0.0 4.4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39348.1 - 1.2e-22 80.5 0.0 2.1e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY39348.1 - 0.0021 16.9 0.4 0.012 14.5 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 CBY39348.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 CBY39348.1 - 0.099 12.2 0.0 0.35 10.4 0.0 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 CBY39349.1 - 9.3e-43 146.6 34.2 2.9e-27 95.6 15.9 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CBY39349.1 - 9.1e-14 50.9 34.2 1.2e-11 43.9 34.4 2.7 1 1 0 1 1 1 1 Amino acid permease zf-HC5HC2H PF13771.6 CBY39352.1 - 4.1e-11 43.0 9.6 4.1e-11 43.0 9.6 5.0 4 2 0 4 4 4 1 PHD-like zinc-binding domain zf-RING_2 PF13639.6 CBY39352.1 - 0.00084 19.6 43.7 0.0049 17.2 12.9 4.7 5 1 0 5 5 5 3 Ring finger domain Cyclin_N PF00134.23 CBY39353.1 - 1.6e-22 79.6 1.2 1.8e-22 79.4 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY39353.1 - 8.4e-05 22.6 0.1 0.00023 21.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain MBF1 PF08523.10 CBY39354.1 - 8.5e-21 74.2 2.7 1.8e-20 73.1 2.7 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CBY39354.1 - 6.4e-13 48.5 0.3 1.1e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 CBY39354.1 - 0.00024 21.1 0.9 0.00041 20.3 0.9 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 CBY39354.1 - 0.009 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Tubulin PF00091.25 CBY39355.1 - 7.7e-17 62.1 1.1 1.3e-16 61.4 0.2 1.9 2 1 1 3 3 3 1 Tubulin/FtsZ family, GTPase domain Helicase_C PF00271.31 CBY39356.1 - 2.8e-26 92.1 0.1 5.1e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.32 CBY39356.1 - 4.2e-05 24.2 0.0 8.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat MDD_C PF18376.1 CBY39357.1 - 1.6e-56 191.0 0.0 2.8e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBY39357.1 - 7.3e-06 26.1 1.5 2.6e-05 24.3 1.5 2.0 3 0 0 3 3 3 1 GHMP kinases N terminal domain Glyco_hydro_72 PF03198.14 CBY39357.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Carboxyl_trans PF01039.22 CBY39358.1 - 3.9e-105 352.3 0.0 4.5e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBY39358.1 - 0.0048 16.4 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) Fibrinogen_C PF00147.18 CBY39359.1 - 5.5e-90 301.0 29.6 1.3e-48 165.8 12.0 2.1 2 0 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain BatA PF07584.11 CBY39360.1 - 0.033 14.6 0.1 0.072 13.5 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal CDO_I PF05995.12 CBY39361.1 - 1.5e-08 34.1 0.0 2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I zf-C2H2 PF00096.26 CBY39362.1 - 4.2e-07 30.1 9.7 0.0032 17.8 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY39362.1 - 2e-05 24.8 5.5 0.019 15.4 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CBY39362.1 - 0.014 16.2 0.2 0.014 16.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY39362.1 - 0.096 13.0 3.2 3.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY39362.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double domain FTH PF01827.27 CBY39363.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 FTH domain WD40 PF00400.32 CBY39364.1 - 0.00012 22.8 4.9 0.18 12.7 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY39364.1 - 0.0009 19.5 0.7 1.6 9.1 0.2 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1921 PF09081.10 CBY39364.1 - 0.0018 18.5 0.3 0.13 12.5 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1921) Mcl1_mid PF12341.8 CBY39364.1 - 0.021 14.2 0.0 0.063 12.6 0.0 1.7 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region BBS2_Mid PF14783.6 CBY39364.1 - 0.14 12.2 0.3 1.2 9.2 0.2 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TIM PF00121.18 CBY39365.1 - 5.1e-92 307.6 0.1 5.8e-92 307.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 CBY39365.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 CutC family RabGAP-TBC PF00566.18 CBY39366.1 - 1.8e-36 125.9 0.3 1.8e-36 125.9 0.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain T6PP_N PF18572.1 CBY39366.1 - 0.076 12.9 0.8 0.43 10.4 0.8 2.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Ald_Xan_dh_C2 PF02738.18 CBY39367.1 - 7.2e-60 203.0 0.2 1e-59 202.4 0.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY39367.1 - 3.1e-19 69.3 0.6 6.6e-19 68.3 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 CBY39367.1 - 5.8e-12 45.9 0.0 1.4e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 CBY39367.1 - 0.0077 16.2 1.5 0.011 15.7 0.1 2.1 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fib_alpha PF08702.10 CBY39367.1 - 0.17 12.1 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Collagen PF01391.18 CBY39368.1 - 7.2e-24 83.3 91.4 2e-09 37.0 21.8 3.8 2 1 2 4 4 4 4 Collagen triple helix repeat (20 copies) Endostatin PF06482.11 CBY39368.1 - 2e-16 60.4 3.2 2.3e-16 60.1 3.2 1.0 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin WD40 PF00400.32 CBY39369.1 - 2.3e-14 53.6 8.4 0.00013 22.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY39369.1 - 2.6e-10 40.5 5.3 0.00037 20.7 0.0 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY39369.1 - 5.4e-06 26.4 0.5 0.1 12.5 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CBY39369.1 - 0.087 11.9 0.1 1.7 7.6 0.2 2.2 1 1 1 2 2 2 0 Coatomer WD associated region TFIIIC_delta PF12657.7 CBY39369.1 - 0.11 12.4 1.1 0.2 11.6 0.3 1.8 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term HGTP_anticodon PF03129.20 CBY39370.1 - 1.5e-12 47.5 0.0 4.7e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBY39370.1 - 9.5e-12 45.2 0.4 4.7e-11 43.0 0.4 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AhpC-TSA PF00578.21 CBY39370.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family WHEP-TRS PF00458.20 CBY39370.1 - 0.2 11.9 3.7 0.46 10.7 3.7 1.6 1 0 0 1 1 1 0 WHEP-TRS domain MTCP1 PF08991.10 CBY39372.1 - 0.0008 19.6 2.3 0.0018 18.5 2.3 1.6 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CBY39372.1 - 0.00094 19.2 3.4 0.0016 18.6 3.4 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CBY39372.1 - 0.03 14.3 1.5 0.057 13.4 1.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 CBY39372.1 - 0.58 9.9 3.9 0.2 11.4 1.1 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) EF-hand_1 PF00036.32 CBY39373.1 - 3.2e-12 45.1 7.8 2.3e-06 26.7 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CBY39373.1 - 3.4e-11 43.4 11.1 1.3e-08 35.2 0.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY39373.1 - 8.2e-11 40.9 4.6 7.4e-06 25.2 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY39373.1 - 1.1e-10 40.5 6.4 9.2e-05 22.1 0.0 4.6 4 1 0 4 4 4 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY39373.1 - 3.1e-05 24.2 9.3 0.01 16.1 3.9 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CBY39373.1 - 0.0002 21.1 5.4 0.24 11.3 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 CBY39373.1 - 0.0015 18.7 0.5 0.12 12.6 0.1 3.0 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_3 PF09069.11 CBY39373.1 - 0.0021 18.4 0.4 1 9.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand adh_short PF00106.25 CBY39375.1 - 4.1e-49 166.7 1.9 5.1e-49 166.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY39375.1 - 3e-34 118.6 0.6 3.9e-34 118.2 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY39375.1 - 8.2e-09 35.6 1.9 9.5e-09 35.4 1.1 1.4 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 CBY39375.1 - 0.0024 17.2 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CBY39375.1 - 0.0072 16.2 0.6 0.014 15.3 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF155 PF02582.14 CBY39375.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 ApbA PF02558.16 CBY39375.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.6 CBY39375.1 - 0.03 15.0 0.1 0.078 13.7 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 CBY39375.1 - 0.038 13.3 1.3 0.058 12.7 1.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.13 CBY39375.1 - 0.052 12.9 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) OKR_DC_1_N PF03709.15 CBY39375.1 - 0.11 12.8 0.0 4.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain SSP160 PF06933.11 CBY39377.1 - 0.022 13.0 13.9 0.028 12.6 13.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 CBY39377.1 - 0.3 9.0 4.7 0.42 8.5 4.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CBY39377.1 - 0.93 9.5 30.1 0.077 13.0 24.3 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein SPATA48 PF15073.6 CBY39381.1 - 1.5e-06 28.5 0.9 3.5e-06 27.4 0.9 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 48 Pkinase PF00069.25 CBY39383.1 - 4.9e-38 131.0 0.1 5.8e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39383.1 - 3.8e-19 69.0 0.0 4.5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39383.1 - 4.8e-07 29.4 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY39383.1 - 1.9e-05 23.8 0.6 2.3e-05 23.5 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY39383.1 - 5.2e-05 22.2 0.0 6.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY39383.1 - 6.7e-05 22.6 1.7 9e-05 22.1 1.7 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBY39383.1 - 0.00021 21.3 0.5 0.00034 20.6 0.5 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY39383.1 - 0.00078 18.8 0.9 0.0011 18.3 0.9 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-PolyVal PF18762.1 CBY39383.1 - 0.07 13.1 0.5 0.12 12.3 0.5 1.4 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins FTA2 PF13095.6 CBY39383.1 - 0.1 12.2 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ets PF00178.22 CBY39384.1 - 1.8e-35 121.2 0.2 3.5e-35 120.3 0.2 1.5 1 0 0 1 1 1 1 Ets-domain Pet20 PF08692.10 CBY39385.1 - 0.48 11.1 4.4 0.22 12.2 1.1 2.2 1 1 1 2 2 2 0 Mitochondrial protein Pet20 Dishevelled PF02377.15 CBY39385.1 - 1.2 9.6 9.3 0.23 11.9 3.6 2.0 2 0 0 2 2 2 0 Dishevelled specific domain DUF5089 PF17002.5 CBY39385.1 - 1.3 8.8 16.0 1.1 9.1 14.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) EGF_3 PF12947.7 CBY39386.1 - 3.4e-10 39.9 7.2 7.4e-10 38.9 7.2 1.6 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 CBY39386.1 - 7.7e-08 32.4 5.7 2.3e-07 30.9 5.7 1.8 1 0 0 1 1 1 1 Calcium-binding EGF domain hEGF PF12661.7 CBY39386.1 - 0.00058 20.4 1.5 0.0014 19.2 1.5 1.7 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.27 CBY39386.1 - 0.0015 18.8 8.0 0.0028 17.9 8.0 1.5 1 0 0 1 1 1 1 EGF-like domain FXa_inhibition PF14670.6 CBY39386.1 - 0.04 14.2 3.4 0.12 12.7 3.4 1.8 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY39386.1 - 0.15 12.0 0.3 0.15 12.0 0.3 2.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.13 CBY39386.1 - 4 7.9 6.9 8.9 6.8 6.9 1.6 1 0 0 1 1 1 0 EGF-like domain Sulfotransfer_1 PF00685.27 CBY39387.1 - 1.6e-12 47.5 0.1 2.8e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY39387.1 - 0.0018 18.7 0.1 0.3 11.4 0.0 2.7 1 1 1 3 3 3 1 Sulfotransferase family Thioredoxin PF00085.20 CBY39388.1 - 1.5e-56 188.8 0.6 1e-30 105.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY39388.1 - 1.2e-08 35.3 2.0 0.0004 20.8 0.2 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY39388.1 - 4.8e-08 33.1 0.1 0.0032 17.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY39388.1 - 6.2e-08 32.9 0.1 0.03 14.6 0.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like AhpC-TSA PF00578.21 CBY39388.1 - 3.1e-07 30.3 0.2 0.032 14.2 0.0 2.5 2 1 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 CBY39388.1 - 8.3e-06 25.4 0.0 0.0087 15.4 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CBY39388.1 - 0.001 19.2 0.6 0.16 12.1 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 CBY39388.1 - 0.0016 18.1 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 CBY39388.1 - 0.005 16.9 0.3 0.57 10.3 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin domain Calsequestrin PF01216.17 CBY39388.1 - 0.0078 15.3 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin TraF PF13728.6 CBY39388.1 - 0.067 13.0 0.0 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein WD40 PF00400.32 CBY39389.1 - 1.6e-08 35.0 0.2 0.0033 18.2 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.25 CBY39390.1 - 3.6e-54 183.9 0.0 4.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY39390.1 - 4.7e-24 85.1 0.0 7.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY39390.1 - 0.00028 20.3 0.1 0.00099 18.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBY39390.1 - 0.00043 19.2 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY39390.1 - 0.0095 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY39390.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Argos PF11581.8 CBY39390.1 - 0.061 13.4 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos DSPc PF00782.20 CBY39391.1 - 1e-12 48.0 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBY39391.1 - 0.016 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 CBY39391.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Acyl-CoA_dh_1 PF00441.24 CBY39392.1 - 1.5e-40 138.9 1.3 2.2e-40 138.3 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY39392.1 - 3.5e-25 88.0 0.0 6.3e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY39392.1 - 5.2e-24 85.1 0.0 1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBY39392.1 - 2.1e-16 60.4 0.4 3.3e-16 59.8 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY39392.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal KASH_CCD PF14662.6 CBY39395.1 - 0.0036 17.2 23.7 0.0036 17.2 23.7 8.9 2 2 8 10 10 10 2 Coiled-coil region of CCDC155 or KASH HAS-barrel PF09378.10 CBY39396.1 - 0.07 13.3 0.0 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 HAS barrel domain Tfb2_C PF18307.1 CBY39396.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Alk_phosphatase PF00245.20 CBY39397.1 - 3.1e-39 135.1 0.1 3.3e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase EF-hand_7 PF13499.6 CBY39398.1 - 3.9e-06 27.2 3.0 5.9e-05 23.4 0.3 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY39398.1 - 8.4e-06 25.3 0.3 0.2 11.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY39398.1 - 0.022 14.3 0.0 0.35 10.5 0.0 2.8 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 CBY39398.1 - 0.059 12.9 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 EF hand JmjC PF02373.22 CBY39399.1 - 7.3e-37 126.3 0.1 1.7e-36 125.1 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CBY39399.1 - 1e-11 44.6 0.3 3e-11 43.1 0.3 1.9 1 0 0 1 1 1 1 jmjN domain Got1 PF04178.12 CBY39400.1 - 2.7e-28 98.6 9.9 3.6e-28 98.3 9.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Glyco_transf_7C PF02709.14 CBY39402.1 - 1.2e-24 85.7 0.7 2.1e-24 85.0 0.7 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 CBY39402.1 - 1.6e-07 31.1 2.0 3.3e-07 30.0 2.0 1.6 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 OAD_gamma PF04277.13 CBY39402.1 - 0.072 13.7 0.5 0.13 12.8 0.5 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3212 PF11486.8 CBY39403.1 - 0.062 13.3 0.4 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) Sec6 PF06046.13 CBY39404.1 - 3.7e-76 256.7 0.1 8.9e-76 255.5 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 Focal_AT PF03623.13 CBY39404.1 - 0.016 15.2 3.6 0.71 9.9 1.3 3.3 4 0 0 4 4 4 0 Focal adhesion targeting region Dynactin_p22 PF07426.11 CBY39404.1 - 2.6 7.9 8.2 0.77 9.6 4.6 2.0 2 1 0 2 2 2 0 Dynactin subunit p22 MCM6_C PF18263.1 CBY39404.1 - 3.1 8.1 6.0 12 6.2 1.9 3.1 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain CorA PF01544.18 CBY39404.1 - 3.2 7.0 8.3 1.6 8.0 4.4 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SOAR PF16533.5 CBY39404.1 - 5.7 7.0 7.7 1.4 8.9 1.4 3.0 3 0 0 3 3 3 0 STIM1 Orai1-activating region PCRF PF03462.18 CBY39404.1 - 5.8 6.7 8.2 3.3 7.5 3.2 2.5 1 1 1 2 2 2 0 PCRF domain UbiA PF01040.18 CBY39405.1 - 1.1e-29 103.5 6.8 2.3e-29 102.5 6.8 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF778 PF05608.12 CBY39406.1 - 1.1e-41 143.3 4.8 2.4e-22 80.2 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 CBY39406.1 - 0.014 15.0 0.1 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 CBY39406.1 - 0.043 13.7 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain WD40 PF00400.32 CBY39407.1 - 2.8e-31 107.0 7.3 9.3e-06 26.3 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY39407.1 - 5e-08 33.1 0.1 0.14 12.5 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY39407.1 - 0.035 12.8 0.1 2.8 6.5 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CBY39407.1 - 0.067 12.5 0.0 9.5 5.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 CBY39407.1 - 0.13 12.1 0.8 35 4.2 0.0 3.8 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A SPT2 PF08243.11 CBY39407.1 - 0.66 10.5 6.1 1.4 9.5 6.1 1.5 1 0 0 1 1 1 0 SPT2 chromatin protein zf-C2H2 PF00096.26 CBY39408.1 - 9.8e-05 22.6 14.3 0.17 12.4 2.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY39408.1 - 0.00012 22.3 9.8 0.014 15.8 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY39408.1 - 0.0024 18.1 11.7 0.083 13.2 0.5 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY39408.1 - 0.0069 17.1 15.5 0.22 12.5 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY39408.1 - 0.009 15.8 4.8 0.009 15.8 4.8 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain CpXC PF14353.6 CBY39408.1 - 0.026 14.5 0.5 0.81 9.8 0.1 2.3 2 0 0 2 2 2 0 CpXC protein Actin_micro PF17003.5 CBY39408.1 - 0.027 13.7 7.6 0.71 9.0 2.2 2.1 1 1 1 2 2 2 0 Putative actin-like family zf_C2H2_ZHX PF18387.1 CBY39408.1 - 0.034 13.8 1.0 0.86 9.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 CBY39408.1 - 0.036 14.5 4.3 1.2 9.7 0.5 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_8 PF15909.5 CBY39408.1 - 0.076 13.3 2.4 7.5 6.9 0.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CBY39408.1 - 0.077 12.8 1.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DIX PF00778.17 CBY39408.1 - 0.083 12.7 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 DIX domain Zn-ribbon_8 PF09723.10 CBY39408.1 - 0.12 12.5 1.5 9.1 6.5 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-MYST PF17772.1 CBY39408.1 - 0.24 11.0 3.7 0.32 10.6 0.5 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain Rubredoxin_2 PF18073.1 CBY39408.1 - 0.5 10.1 1.9 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-Di19 PF05605.12 CBY39408.1 - 0.59 10.5 4.9 3.1 8.2 0.6 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY39408.1 - 6.1 7.4 8.2 0.94 10.0 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Sec2p PF06428.11 CBY39411.1 - 0.013 15.5 3.7 0.056 13.4 3.3 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p ANAPC4 PF12896.7 CBY39411.1 - 0.12 11.8 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 AAA_23 PF13476.6 CBY39411.1 - 0.23 11.9 4.8 0.25 11.8 4.8 1.1 1 0 0 1 1 1 0 AAA domain Arm PF00514.23 CBY39412.1 - 7.3e-51 168.7 18.5 6.4e-09 35.6 0.2 11.6 12 0 0 12 12 12 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBY39412.1 - 2.7e-10 39.6 0.7 0.62 10.5 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CBY39412.1 - 3.8e-09 36.8 8.9 0.00021 21.6 0.0 6.2 4 2 2 6 6 6 3 HEAT repeats KAP PF05804.12 CBY39412.1 - 2.9e-07 29.1 8.8 8.5e-07 27.5 6.2 2.4 1 1 1 3 3 3 1 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 CBY39412.1 - 1e-06 29.1 9.6 1.7 9.3 0.0 7.3 7 1 1 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 CBY39412.1 - 1.2e-05 25.4 2.4 0.14 12.2 0.0 4.1 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 CBY39412.1 - 2e-05 24.5 0.7 0.00027 20.9 0.2 3.0 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 CBY39412.1 - 5e-05 22.9 5.8 0.072 12.5 2.1 4.1 2 1 3 5 5 5 3 Armadillo-like V-ATPase_H_C PF11698.8 CBY39412.1 - 0.024 14.7 6.1 30 4.8 0.2 5.0 3 1 3 6 6 6 0 V-ATPase subunit H GSK-3_bind PF05350.12 CBY39412.1 - 0.11 11.8 0.7 0.24 10.7 0.1 1.8 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding RasGEF_N_2 PF14663.6 CBY39412.1 - 0.25 11.7 1.7 14 6.1 0.0 3.8 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GED PF02212.18 CBY39413.1 - 5.5e-23 80.9 3.0 7.6e-23 80.5 3.0 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF2780 PF11075.8 CBY39413.1 - 0.0059 16.8 0.2 0.011 15.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) EloA-BP1 PF15870.5 CBY39414.1 - 1.6e-16 61.0 0.1 3.4e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 ElonginA binding-protein 1 Rsd_AlgQ PF04353.13 CBY39414.1 - 0.099 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CHORD PF04968.12 CBY39414.1 - 0.82 10.4 6.8 2.1 9.2 6.8 1.6 1 0 0 1 1 1 0 CHORD Helicase_PWI PF18149.1 CBY39415.1 - 1.3e-31 109.0 3.8 1.3e-31 109.0 3.8 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain DEAD PF00270.29 CBY39415.1 - 8.9e-27 94.0 0.0 2.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY39415.1 - 2.4e-15 57.0 0.2 7.7e-14 52.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBY39415.1 - 0.00011 22.5 0.5 0.0015 18.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBY39415.1 - 0.042 14.2 0.5 0.65 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain RhoGAP PF00620.27 CBY39415.1 - 0.19 11.5 2.3 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 RhoGAP domain LprI PF07007.12 CBY39415.1 - 1 10.0 4.9 0.33 11.6 0.4 2.5 3 1 0 3 3 3 0 Lysozyme inhibitor LprI FA_hydroxylase PF04116.13 CBY39416.1 - 1.5e-11 44.7 7.3 1.5e-11 44.7 7.3 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CBY39416.1 - 2.4e-09 37.2 1.3 4.6e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.13 CBY39416.1 - 0.053 13.7 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DSPc PF00782.20 CBY39417.1 - 1.8e-24 86.1 0.5 2.6e-24 85.5 0.1 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY39417.1 - 0.0052 16.8 0.1 0.007 16.4 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY39417.1 - 0.019 15.1 3.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate z-alpha PF02295.17 CBY39417.1 - 0.2 11.8 1.5 0.41 10.7 1.5 1.5 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain Consortin_C PF15281.6 CBY39417.1 - 2.2 8.3 4.8 0.92 9.5 0.6 2.5 3 1 0 3 3 3 0 Consortin C-terminus RP853 PF17542.2 CBY39418.1 - 0.0022 17.2 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized RP853 VWA_2 PF13519.6 CBY39419.1 - 0.0011 19.5 0.0 0.64 10.7 0.0 2.9 3 0 0 3 3 3 2 von Willebrand factor type A domain NDUFB10 PF10249.9 CBY39420.1 - 8.3e-25 87.7 2.0 1.2e-24 87.3 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Peptidase_M17 PF00883.21 CBY39421.1 - 7.2e-124 413.1 1.1 2.3e-108 362.1 0.0 2.5 2 1 1 3 3 3 2 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CBY39421.1 - 3.9e-09 36.4 0.1 7.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Hira PF07569.11 CBY39421.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split A_deamin PF02137.18 CBY39422.1 - 9.5e-11 41.7 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2681 PF10883.8 CBY39424.1 - 0.04 14.3 0.1 0.061 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Chordopox_A13L PF05961.11 CBY39424.1 - 0.76 10.1 2.4 2.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein HEAT PF02985.22 CBY39425.1 - 1.2e-05 25.1 0.4 0.07 13.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBY39425.1 - 0.0051 17.3 4.7 0.71 10.4 0.1 4.8 4 2 2 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 CBY39425.1 - 0.0076 16.6 0.0 0.65 10.4 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats SIR2 PF02146.17 CBY39426.1 - 0.00021 21.3 0.1 0.00034 20.6 0.1 1.4 1 0 0 1 1 1 1 Sir2 family Phi-29_GP16_7 PF06720.11 CBY39426.1 - 0.021 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 EzrA PF06160.12 CBY39426.1 - 0.062 11.5 0.1 0.075 11.2 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TFA2_Winged_2 PF18121.1 CBY39426.1 - 0.072 12.8 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 YvrJ PF12841.7 CBY39426.1 - 0.17 11.4 0.7 0.26 10.9 0.7 1.3 1 0 0 1 1 1 0 YvrJ protein family SIR2 PF02146.17 CBY39427.1 - 1.4e-14 54.4 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1258 PF06869.12 CBY39427.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Carb_anhydrase PF00194.21 CBY39430.1 - 0.005 16.4 0.1 0.0055 16.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 CBY39431.1 - 1.3e-54 185.4 0.2 1.7e-54 185.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase SH3BP5 PF05276.14 CBY39433.1 - 1e-72 244.7 25.0 1.8e-72 243.9 25.0 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Pox_A_type_inc PF04508.12 CBY39433.1 - 0.12 12.3 1.3 1.6 8.7 0.0 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.11 CBY39433.1 - 1 9.8 5.5 5.7 7.4 0.3 3.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2797 PF10977.8 CBY39433.1 - 2.3 8.0 7.5 2.7 7.8 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) NDK PF00334.19 CBY39434.1 - 1.8e-35 121.9 0.0 1.4e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 Nucleoside diphosphate kinase Methyltransf_25 PF13649.6 CBY39434.1 - 1.4e-08 35.3 0.1 3.3e-07 30.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY39434.1 - 2.7e-08 33.8 0.1 8.7e-08 32.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY39434.1 - 2.4e-06 28.1 0.0 1.3e-05 25.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY39434.1 - 6.5e-06 26.8 0.0 1.7e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY39434.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain JmjC PF02373.22 CBY39435.1 - 3.1e-12 46.9 1.4 8.6e-11 42.3 1.4 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBY39435.1 - 8.8e-10 38.7 0.0 9.6e-09 35.3 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JHD PF17811.1 CBY39435.1 - 8.4e-07 29.5 0.5 1.7e-06 28.5 0.5 1.5 1 0 0 1 1 1 1 Jumonji helical domain Cupin_2 PF07883.11 CBY39435.1 - 0.03 14.1 0.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Cupin domain F-box-like PF12937.7 CBY39436.1 - 3.8e-07 29.9 0.1 1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY39436.1 - 6.7e-05 22.7 0.0 0.00021 21.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 CBY39436.1 - 0.0043 17.0 0.0 14 6.1 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat zf-H2C2_5 PF13909.6 CBY39437.1 - 0.029 14.1 11.6 0.079 12.7 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY39437.1 - 0.037 14.5 4.1 0.037 14.5 4.1 6.1 6 0 0 6 6 6 0 Zinc finger, C2H2 type DpnI PF06044.12 CBY39437.1 - 0.62 9.7 7.4 0.27 10.9 4.2 2.0 2 0 0 2 2 2 0 Dam-replacing family zf-met PF12874.7 CBY39437.1 - 0.66 10.5 11.2 2.1 8.9 1.8 3.4 3 1 0 3 3 3 0 Zinc-finger of C2H2 type OrsD PF12013.8 CBY39437.1 - 0.87 10.1 0.0 0.87 10.1 0.0 5.2 2 2 3 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 CBY39437.1 - 4.5 8.4 40.3 0.2 12.6 3.0 6.5 6 1 0 6 6 6 0 C2H2-type zinc finger FOXP-CC PF16159.5 CBY39437.1 - 5.7 7.6 11.2 60 4.4 0.0 3.8 3 1 0 3 3 3 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 CBY39437.1 - 6.5 7.0 9.7 0.93 9.7 0.9 3.1 3 0 0 3 3 3 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 CBY39438.1 - 0.0089 16.4 15.6 0.25 11.8 0.3 5.0 4 1 0 4 4 4 2 Zinc-finger double domain OrsD PF12013.8 CBY39438.1 - 0.13 12.7 0.4 0.13 12.7 0.4 4.3 2 2 2 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D PCNA_N PF00705.18 CBY39438.1 - 0.15 11.8 0.4 0.57 9.9 0.1 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain zf-C2H2_8 PF15909.5 CBY39438.1 - 0.43 10.9 8.1 0.19 12.1 5.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 CBY39438.1 - 1.6 9.3 30.5 1.5 9.4 0.2 5.3 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-Sec23_Sec24 PF04810.15 CBY39438.1 - 1.7 8.8 6.6 0.6 10.2 0.9 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.12 CBY39438.1 - 4.2 7.7 12.5 8.8 6.7 2.2 3.8 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding C2 PF00168.30 CBY39439.1 - 6.2e-53 177.4 4.9 1.5e-26 92.7 0.2 2.7 3 0 0 3 3 3 2 C2 domain TMEM52 PF14979.6 CBY39439.1 - 0.0025 17.7 1.0 0.0053 16.7 1.0 1.5 1 0 0 1 1 1 1 Transmembrane 52 CEP76-C2 PF15627.6 CBY39439.1 - 0.0064 16.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 CEP76 C2 domain TSGA13 PF14994.6 CBY39439.1 - 0.014 14.8 0.6 0.033 13.6 0.6 1.5 1 0 0 1 1 1 0 Testis-specific gene 13 protein PTEN_C2 PF10409.9 CBY39439.1 - 0.016 15.0 0.9 1 9.1 0.0 2.9 2 0 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein Transglut_C PF00927.22 CBY39439.1 - 0.019 15.1 0.3 7.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Cadherin_C_2 PF16492.5 CBY39439.1 - 0.021 15.6 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 CBY39439.1 - 0.021 15.1 0.3 0.041 14.1 0.3 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.6 CBY39439.1 - 0.04 12.3 1.0 0.79 8.1 0.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.6 CBY39439.1 - 0.044 14.7 1.8 0.14 13.1 1.8 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF997 PF06196.12 CBY39439.1 - 0.052 13.6 0.2 0.092 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) PAG PF15347.6 CBY39439.1 - 0.059 12.4 0.2 0.092 11.7 0.2 1.3 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TMIE PF16038.5 CBY39439.1 - 0.15 12.0 5.0 0.12 12.2 2.4 2.3 2 0 0 2 2 2 0 TMIE protein TRP PF06011.12 CBY39439.1 - 0.19 10.4 0.1 0.29 9.8 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LYRIC PF15686.5 CBY39439.1 - 0.38 10.3 6.9 0.024 14.2 1.4 1.7 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family MAP17 PF15807.5 CBY39439.1 - 0.65 10.2 5.2 0.13 12.5 1.4 1.9 2 1 0 2 2 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CUB PF00431.20 CBY39440.1 - 0.00011 22.6 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 CUB domain MGC-24 PF05283.11 CBY39440.1 - 8.5 6.8 9.2 0.32 11.4 2.9 1.8 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Frag1 PF10277.9 CBY39442.1 - 9.1e-21 74.4 17.5 1.1e-20 74.1 17.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family HOK_GEF PF01848.16 CBY39442.1 - 0.051 13.0 0.3 0.051 13.0 0.3 2.2 2 0 0 2 2 2 0 Hok/gef family MSC PF09402.10 CBY39442.1 - 0.14 11.6 2.4 0.16 11.4 0.6 1.7 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF423 PF04241.15 CBY39442.1 - 1.8 8.9 6.5 0.62 10.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF4131 PF13567.6 CBY39442.1 - 3.7 7.2 9.8 2.3 7.8 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Matrilin_ccoil PF10393.9 CBY39443.1 - 0.17 11.7 0.4 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Tctex-1 PF03645.13 CBY39444.1 - 6.3e-11 42.4 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Tctex-1 family Trypsin PF00089.26 CBY39445.1 - 2.3e-37 128.9 0.0 4.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin ALIX_LYPXL_bnd PF13949.6 CBY39447.1 - 2.5e-79 266.7 20.9 1.6e-78 264.0 9.7 2.4 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 CBY39447.1 - 2.9e-75 253.5 8.0 5.5e-75 252.6 8.0 1.5 1 0 0 1 1 1 1 BRO1-like domain CagS PF16707.5 CBY39447.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Xpo1 PF08389.12 CBY39447.1 - 0.21 11.6 1.7 0.47 10.5 0.6 2.2 2 1 0 2 2 2 0 Exportin 1-like protein DUF4709 PF15821.5 CBY39447.1 - 0.6 10.4 6.0 0.83 10.0 0.4 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4709) DUF2203 PF09969.9 CBY39447.1 - 7.7 7.3 7.6 4.1 8.1 0.2 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SKIP_SNW PF02731.15 CBY39448.1 - 8.2e-35 119.8 1.5 8.2e-35 119.8 1.5 1.6 2 0 0 2 2 2 1 SKIP/SNW domain UCH PF00443.29 CBY39449.1 - 2.4e-08 33.8 13.7 6.6e-07 29.1 13.7 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CBY39449.1 - 4.5e-08 32.8 0.0 0.00031 20.6 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 CBY39449.1 - 0.13 12.1 0.1 0.53 10.2 0.1 2.0 1 0 0 1 1 1 0 UBA-like domain Atypical_Card PF18461.1 CBY39449.1 - 0.63 10.3 3.8 41 4.5 0.1 3.9 4 0 0 4 4 4 0 Atypical caspase recruitment domain Linker_histone PF00538.19 CBY39449.1 - 1.2 9.6 6.4 6.9 7.1 0.0 3.4 3 0 0 3 3 3 0 linker histone H1 and H5 family Sulfatase PF00884.23 CBY39450.1 - 8.3e-58 196.2 0.2 1.4e-57 195.5 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY39450.1 - 6.5e-05 22.7 1.8 0.00011 21.9 0.1 2.1 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 CBY39450.1 - 0.0058 17.4 2.8 0.033 14.9 0.5 2.8 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 CBY39450.1 - 0.034 14.4 2.8 0.59 10.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) Trypsin PF00089.26 CBY39451.1 - 4.9e-53 180.2 0.8 6.8e-53 179.7 0.8 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY39451.1 - 2.6e-10 41.4 0.0 4.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY39451.1 - 0.011 15.3 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 DUF1986 PF09342.11 CBY39451.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) zf-MYND PF01753.18 CBY39455.1 - 1.1e-06 28.6 17.8 1.5e-06 28.2 17.8 1.3 1 0 0 1 1 1 1 MYND finger Nup96 PF12110.8 CBY39456.1 - 6.5e-69 232.3 0.0 1e-68 231.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Sec16_C PF12931.7 CBY39456.1 - 0.012 15.3 0.2 0.048 13.3 0.0 2.0 3 0 0 3 3 3 0 Sec23-binding domain of Sec16 ABC2_membrane_5 PF13346.6 CBY39457.1 - 0.0081 15.7 0.5 0.011 15.3 0.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Piezo_RRas_bdg PF12166.8 CBY39457.1 - 0.16 11.2 0.3 0.21 10.8 0.3 1.1 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain E1-E2_ATPase PF00122.20 CBY39458.1 - 4.4e-47 159.9 3.0 5.6e-47 159.6 0.8 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBY39458.1 - 7.8e-12 45.1 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY39458.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBY39458.1 - 0.056 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MgtE PF01769.16 CBY39458.1 - 0.1 13.0 5.2 1.8 9.0 2.7 2.5 2 0 0 2 2 2 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 CBY39458.1 - 0.27 11.3 7.1 2.3 8.3 4.7 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III An_peroxidase PF03098.15 CBY39459.1 - 0.0051 15.4 0.0 0.0088 14.7 0.0 1.3 1 0 0 1 1 1 1 Animal haem peroxidase HU-CCDC81_euk_2 PF18289.1 CBY39459.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 MCM_bind PF09739.9 CBY39460.1 - 1.1e-50 172.7 0.6 1.2e-50 172.6 0.6 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 CBY39460.1 - 0.1 13.1 0.3 0.19 12.1 0.3 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain Serinc PF03348.15 CBY39461.1 - 6.7e-33 114.3 23.3 8.3e-33 113.9 23.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) ASFV_L11L PF05293.11 CBY39461.1 - 0.001 19.4 0.7 0.0042 17.4 0.7 2.0 1 0 0 1 1 1 1 African swine fever virus (ASFV) L11L protein Peptidase_M13_N PF05649.13 CBY39463.1 - 4.1e-75 253.8 0.6 5.4e-75 253.5 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CBY39463.1 - 2e-66 223.5 0.1 3.3e-66 222.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 RhoGAP PF00620.27 CBY39464.1 - 4.3e-38 130.5 0.1 1.1e-37 129.2 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CBY39464.1 - 4.5e-07 29.7 7.3 9.7e-07 28.6 7.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 CBY39464.1 - 0.00013 22.2 3.8 0.00045 20.4 3.8 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_9 PF13901.6 CBY39464.1 - 0.0053 16.8 4.7 0.013 15.5 4.7 1.6 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon C1_2 PF03107.16 CBY39464.1 - 0.093 13.1 2.4 0.22 11.8 2.4 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 CBY39464.1 - 0.17 11.5 1.8 0.4 10.3 1.8 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 CBY39464.1 - 0.2 11.8 3.4 0.44 10.7 3.4 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 CBY39464.1 - 0.3 11.0 3.4 0.65 10.0 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CBY39464.1 - 0.67 9.9 4.4 1.9 8.5 4.4 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 CBY39464.1 - 2.4 8.3 5.2 9.6 6.4 5.2 2.0 1 1 0 1 1 1 0 PHD-finger SID-1_RNA_chan PF13965.6 CBY39465.1 - 0.015 13.8 0.1 0.018 13.5 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UCR_UQCRX_QCR9 PF05365.12 CBY39465.1 - 0.093 12.7 0.7 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Kei1 PF08552.11 CBY39465.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FGFR3_TM PF18123.1 CBY39465.1 - 3 7.4 7.7 5.2 6.7 7.7 1.2 1 0 0 1 1 1 0 Fibroblast growth factor receptor 3 transmembrane domain CUB PF00431.20 CBY39466.1 - 5e-35 120.2 2.2 2.5e-17 63.2 0.2 2.6 3 0 0 3 3 3 2 CUB domain Trypsin PF00089.26 CBY39466.1 - 3.5e-06 27.0 0.2 8.7e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 Trypsin zf-C3HC4_3 PF13920.6 CBY39467.1 - 4.7e-06 26.4 12.6 1.3e-05 24.9 12.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY39467.1 - 0.00035 20.4 8.7 0.0032 17.3 9.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY39467.1 - 0.028 14.3 9.9 0.043 13.6 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YdjO PF14169.6 CBY39467.1 - 0.37 10.6 9.0 2.5 7.9 0.4 3.3 2 1 1 3 3 3 0 Cold-inducible protein YdjO Prok-RING_4 PF14447.6 CBY39467.1 - 0.41 10.5 10.1 1.1 9.1 9.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ArfGap PF01412.18 CBY39467.1 - 1.5 8.9 10.4 2.8 8.0 10.1 1.6 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf zf-RING_5 PF14634.6 CBY39467.1 - 6 6.9 13.7 70 3.5 12.7 2.4 1 1 1 2 2 2 0 zinc-RING finger domain EGF_CA PF07645.15 CBY39468.1 - 7.5e-07 29.2 12.5 7.5e-07 29.2 12.5 8.4 8 0 0 8 8 8 5 Calcium-binding EGF domain cEGF PF12662.7 CBY39468.1 - 0.00039 20.3 62.7 0.22 11.5 1.4 8.4 7 1 0 7 7 7 5 Complement Clr-like EGF-like ITI_HC_C PF06668.12 CBY39468.1 - 0.00039 20.1 0.0 0.00039 20.1 0.0 1.9 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus EGF_3 PF12947.7 CBY39468.1 - 0.00058 20.0 114.9 0.0088 16.2 8.1 8.1 8 0 0 8 8 8 5 EGF domain EGF_MSP1_1 PF12946.7 CBY39468.1 - 0.021 14.9 8.3 0.021 14.9 8.3 8.0 9 0 0 9 9 9 0 MSP1 EGF domain 1 zf-C3HC4_3 PF13920.6 CBY39469.1 - 6.2e-06 26.0 4.2 9.4e-06 25.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY39469.1 - 0.24 11.3 5.1 0.36 10.7 5.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RVT_1 PF00078.27 CBY39471.1 - 5.6e-13 48.9 0.1 2e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CBY39471.1 - 6.9e-10 38.9 0.3 3.4e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY39471.1 - 3.8e-09 36.8 0.0 8.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Sina PF03145.16 CBY39475.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C4 PF00105.18 CBY39476.1 - 8.7e-16 58.1 10.6 1.4e-15 57.5 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RRPl_C4 PF17026.5 CBY39476.1 - 0.034 14.3 3.9 0.059 13.5 3.9 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.16 CBY39476.1 - 7 7.1 7.0 0.46 10.8 0.4 2.2 2 0 0 2 2 2 0 C1 domain MFS_1 PF07690.16 CBY39477.1 - 5.1e-20 71.7 36.7 1.6e-19 70.1 23.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin PF00089.26 CBY39478.1 - 1.5e-44 152.5 0.7 1.5e-44 152.5 0.7 2.0 2 0 0 2 2 2 1 Trypsin DUF1986 PF09342.11 CBY39478.1 - 0.19 12.2 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Mucin PF01456.17 CBY39478.1 - 0.89 9.5 19.2 1.9 8.4 19.2 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Crisp PF08562.10 CBY39478.1 - 6.1 7.5 12.6 0.24 12.0 2.1 3.1 2 1 0 2 2 2 0 Crisp Mad3_BUB1_I PF08311.12 CBY39479.1 - 0.014 15.4 4.8 1.2 9.1 2.9 3.0 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Activator-TraM PF11657.8 CBY39479.1 - 1.3 8.8 7.9 1.8 8.4 6.4 2.1 1 1 1 2 2 2 0 Transcriptional activator TraM Fib_alpha PF08702.10 CBY39479.1 - 6.2 7.0 7.4 35 4.6 4.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RRM_1 PF00076.22 CBY39480.1 - 3.1e-09 36.5 0.0 4.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 CBY39482.1 - 7e-12 44.0 3.6 1.2e-05 24.6 1.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY39482.1 - 8.6e-12 45.3 0.9 2.4e-11 43.9 0.9 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY39482.1 - 9.4e-11 40.8 2.4 3.5e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CBY39482.1 - 9e-07 28.7 4.6 1.3e-06 28.1 3.2 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY39482.1 - 9e-07 28.1 3.9 0.014 14.9 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CBY39482.1 - 0.00077 19.7 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain GAGE PF05831.11 CBY39482.1 - 0.0043 17.6 0.8 0.0085 16.6 0.8 1.4 1 0 0 1 1 1 1 GAGE protein EF-hand_14 PF17959.1 CBY39482.1 - 0.097 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 CBY39482.1 - 0.15 12.0 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand UPF0242 PF06785.11 CBY39485.1 - 0.03 14.4 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PsbX PF06596.11 CBY39486.1 - 0.015 15.3 1.0 0.015 15.3 1.0 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) CSRNP_N PF16019.5 CBY39486.1 - 0.033 14.1 5.4 0.061 13.2 5.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus HECT PF00632.25 CBY39488.1 - 2.4e-95 319.6 0.0 3.3e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY39488.1 - 2.4e-37 126.7 26.0 7.2e-11 42.0 2.5 4.5 4 0 0 4 4 4 4 WW domain Rieske PF00355.26 CBY39489.1 - 5e-12 45.6 0.1 8.2e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_2 PF07992.14 CBY39489.1 - 1.2e-09 37.8 0.1 1.9e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY39489.1 - 2e-05 23.9 0.6 2.7e-05 23.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CBY39489.1 - 6.9e-05 22.2 0.2 9.7e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBY39489.1 - 0.00017 22.1 0.2 0.00041 20.8 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY39489.1 - 0.00024 20.0 2.0 0.0004 19.2 2.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CBY39489.1 - 0.00024 20.5 0.0 0.00033 20.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY39489.1 - 0.00037 20.7 0.8 0.00074 19.7 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBY39489.1 - 0.00055 19.1 0.2 0.00072 18.7 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CBY39489.1 - 0.0014 19.0 0.0 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 CBY39489.1 - 0.0028 17.3 1.1 0.0048 16.5 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CBY39489.1 - 0.003 16.9 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CBY39489.1 - 0.0075 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 CBY39489.1 - 0.0095 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CBY39489.1 - 0.016 14.3 0.2 0.021 13.9 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein IlvN PF07991.12 CBY39489.1 - 0.034 13.7 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 CBY39489.1 - 0.044 13.8 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 CBY39489.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 CBY39489.1 - 0.1 12.5 0.0 1.2 9.0 0.0 2.1 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family K_oxygenase PF13434.6 CBY39489.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CBY39489.1 - 0.33 10.3 6.9 0.47 9.7 6.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CBY39489.1 - 0.33 9.8 2.1 0.45 9.3 2.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF5051 PF16473.5 CBY39490.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like mIF3 PF14877.6 CBY39493.1 - 0.047 13.3 0.5 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial translation initiation factor GDPD PF03009.17 CBY39496.1 - 3.7e-15 56.4 1.1 4.9e-15 56.0 1.1 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family VPS53_C PF16854.5 CBY39496.1 - 0.087 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Occludin_ELL PF07303.13 CBY39497.1 - 0.027 15.2 8.0 0.09 13.5 1.5 4.2 3 0 0 3 3 3 0 Occludin homology domain DUF948 PF06103.11 CBY39497.1 - 0.051 13.8 2.3 0.64 10.3 0.1 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3811 PF11656.8 CBY39497.1 - 0.087 13.2 0.8 0.55 10.7 0.1 2.7 2 0 0 2 2 2 0 YjbD family (DUF3811) Tap-RNA_bind PF09162.10 CBY39497.1 - 0.4 10.6 2.8 2.5 8.0 0.0 3.6 4 0 0 4 4 4 0 Tap, RNA-binding FliD_N PF02465.18 CBY39497.1 - 0.87 10.3 8.3 0.2 12.3 1.3 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus THOC7 PF05615.13 CBY39497.1 - 1.7 9.0 13.8 0.23 11.7 0.7 4.5 4 0 0 4 4 4 0 Tho complex subunit 7 UPF0184 PF03670.13 CBY39497.1 - 1.9 9.0 12.2 3.1 8.2 3.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Baculo_PEP_C PF04513.12 CBY39497.1 - 2.3 8.2 10.7 1.8 8.6 0.6 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm2_III-A PF03750.13 CBY39497.1 - 2.9 8.8 15.8 2.4 9.0 1.7 4.8 3 1 2 5 5 5 0 Csm2 Type III-A EGF_CA PF07645.15 CBY39502.1 - 1.5e-31 108.3 78.2 2.1e-07 31.0 13.7 5.7 5 0 0 5 5 5 5 Calcium-binding EGF domain PKD_channel PF08016.12 CBY39502.1 - 7.2e-18 64.5 17.8 7.2e-18 64.5 17.8 2.6 3 0 0 3 3 3 1 Polycystin cation channel hEGF PF12661.7 CBY39502.1 - 1.2e-11 44.8 42.6 0.011 16.3 3.2 6.6 5 0 0 5 5 5 5 Human growth factor-like EGF cEGF PF12662.7 CBY39502.1 - 1.6e-11 43.9 42.6 0.00074 19.4 0.8 5.4 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY39502.1 - 9.3e-08 32.1 69.4 0.00041 20.5 6.1 6.6 5 2 1 6 6 6 4 EGF domain FXa_inhibition PF14670.6 CBY39502.1 - 2.9e-05 24.2 66.8 0.049 13.9 7.2 6.2 3 2 3 6 6 6 4 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY39502.1 - 0.0001 22.5 61.5 0.0019 18.5 7.4 6.0 5 0 0 5 5 5 3 Pvs28 EGF domain EGF PF00008.27 CBY39502.1 - 0.00023 21.4 70.6 0.05 13.9 6.7 6.7 4 1 2 6 6 6 4 EGF-like domain EGF_MSP1_1 PF12946.7 CBY39502.1 - 1.3 9.1 58.9 0.041 14.0 4.7 5.4 5 0 0 5 5 5 0 MSP1 EGF domain 1 Zip PF02535.22 CBY39503.1 - 0.00024 20.5 0.5 0.00033 20.0 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Astacin PF01400.24 CBY39504.1 - 2.4e-22 79.5 0.2 4e-21 75.5 0.2 2.5 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY39504.1 - 2.1e-08 34.2 17.7 2.8e-07 30.6 4.7 12.2 11 1 0 11 11 11 4 Calcium-binding EGF domain cEGF PF12662.7 CBY39504.1 - 7.7e-05 22.5 0.7 7.7e-05 22.5 0.7 9.4 9 1 0 9 9 9 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY39504.1 - 0.0023 18.1 17.3 0.0031 17.7 6.4 13.2 14 0 0 14 14 14 3 EGF domain PH PF00169.29 CBY39505.1 - 7.4e-06 26.4 0.2 9.9e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 PH domain SPO11_like PF03533.14 CBY39507.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 SPO11 homologue zf-H2C2_5 PF13909.6 CBY39508.1 - 3.1e-14 52.4 24.6 7.5e-05 22.4 0.2 6.3 6 1 0 6 6 6 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY39508.1 - 5.9e-10 39.1 33.1 0.00053 20.6 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY39508.1 - 7.6e-10 38.7 29.1 0.00014 22.1 0.3 6.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY39508.1 - 6.4e-07 29.5 29.2 0.069 13.6 0.1 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY39508.1 - 1.2e-05 25.4 19.7 0.0037 17.5 0.5 5.6 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding DUF3458 PF11940.8 CBY39508.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Aldo_ket_red PF00248.21 CBY39508.1 - 0.0077 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2256 PF10013.9 CBY39508.1 - 0.087 13.0 5.1 2.5 8.3 0.0 3.4 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) OrsD PF12013.8 CBY39508.1 - 0.098 13.1 0.1 0.098 13.1 0.1 4.4 3 2 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D Rota_VP4_MID PF17477.2 CBY39508.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain zf-C2H2_2 PF12756.7 CBY39508.1 - 0.13 12.6 21.2 2.1 8.7 11.0 4.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBY39508.1 - 0.52 10.4 0.1 0.52 10.4 0.1 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CBY39508.1 - 2.7 8.5 0.0 2.7 8.5 0.0 4.6 6 0 0 6 6 6 0 Zinc-finger of C2H2 type DNA_RNApol_7kD PF03604.13 CBY39508.1 - 7.7 6.3 10.4 9.5 6.0 0.1 3.5 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Bax1-I PF01027.20 CBY39509.1 - 7.8e-37 127.1 16.5 9e-37 126.9 16.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBY39509.1 - 0.15 11.6 9.9 0.23 11.0 9.9 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like 7TMR-DISM_7TM PF07695.11 CBY39509.1 - 0.69 9.8 13.3 8 6.3 8.4 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2244 PF10003.9 CBY39509.1 - 5.6 6.6 6.4 1 9.0 0.1 2.4 1 1 0 2 2 2 0 Integral membrane protein (DUF2244) TraY PF05509.11 CBY39510.1 - 0.0036 17.3 0.1 0.0084 16.1 0.1 1.6 1 0 0 1 1 1 1 TraY domain ZirS_C PF16583.5 CBY39510.1 - 0.01 15.4 0.1 0.017 14.7 0.1 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain MSC PF09402.10 CBY39512.1 - 0.077 12.4 2.2 0.092 12.2 2.2 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF445 PF04286.12 CBY39512.1 - 0.2 11.4 7.5 0.24 11.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CemA PF03040.14 CBY39512.1 - 0.39 10.6 5.6 2.5 8.0 0.9 2.0 1 1 1 2 2 2 0 CemA family FAM199X PF15814.5 CBY39512.1 - 0.62 9.1 8.9 0.067 12.3 1.4 2.0 2 0 0 2 2 2 0 Protein family FAM199X DUF4337 PF14235.6 CBY39512.1 - 4.4 7.4 10.8 9.7 6.3 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Tantalus PF15386.6 CBY39513.1 - 1.2e-13 50.9 0.4 1.2e-13 50.9 0.4 1.7 2 0 0 2 2 2 1 Drosophila Tantalus-like DUF3896 PF13035.6 CBY39513.1 - 0.78 9.9 6.3 0.11 12.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TRAM_LAG1_CLN8 PF03798.16 CBY39514.1 - 6.5e-15 55.4 7.1 6.5e-15 55.4 7.1 1.7 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 CBY39515.1 - 2.6e-32 112.2 20.3 2.6e-32 112.2 20.3 1.6 2 0 0 2 2 2 1 TLC domain adh_short PF00106.25 CBY39516.1 - 1.2e-41 142.3 3.5 3e-41 141.0 3.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY39516.1 - 2.6e-33 115.6 0.2 4.3e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY39516.1 - 2.3e-11 43.9 0.4 4.5e-11 43.0 0.4 1.4 1 0 0 1 1 1 1 KR domain DUF4313 PF14190.6 CBY39516.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) RBD PF02196.15 CBY39517.1 - 1.8e-12 47.2 0.0 4.1e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Raf-like Ras-binding domain Tau95_N PF17682.1 CBY39518.1 - 0.048 13.9 0.9 0.12 12.5 0.9 1.7 1 0 0 1 1 1 0 Tau95 Triple barrel domain PCI PF01399.27 CBY39519.1 - 4.3e-11 43.3 0.1 1.1e-08 35.5 0.0 3.5 4 1 0 4 4 4 1 PCI domain eIF3m_C_helix PF18005.1 CBY39519.1 - 4.9e-09 35.7 1.0 4.9e-09 35.7 1.0 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix SWI-SNF_Ssr4 PF08549.10 CBY39519.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sacchrp_dh_NADP PF03435.18 CBY39520.1 - 8.3e-19 68.1 0.0 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBY39520.1 - 7.4e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY39520.1 - 0.0013 17.8 0.1 0.003 16.6 0.1 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBY39520.1 - 0.053 13.0 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 CBY39520.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CBY39520.1 - 0.091 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 CBY39520.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DUF2339 PF10101.9 CBY39523.1 - 0.092 11.3 4.9 0.14 10.7 4.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Peptidase_M14 PF00246.24 CBY39524.1 - 3.3e-77 260.2 1.2 4.5e-77 259.7 1.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY39524.1 - 1.3e-14 54.4 1.0 3.3e-14 53.0 0.8 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide CBM_4_9 PF02018.17 CBY39525.1 - 2.5e-11 44.0 8.7 0.00015 22.0 0.6 3.4 3 1 0 3 3 3 3 Carbohydrate binding domain Whirly PF08536.11 CBY39525.1 - 0.13 12.1 0.1 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Whirly transcription factor CBM_6 PF03422.15 CBY39525.1 - 0.13 12.5 3.0 12 6.2 0.3 3.4 2 1 0 3 3 3 0 Carbohydrate binding module (family 6) DnaJ PF00226.31 CBY39527.1 - 1.9e-18 66.3 0.6 3.6e-18 65.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CBY39527.1 - 0.039 14.0 2.8 0.064 13.3 2.8 1.3 1 0 0 1 1 1 0 Pam16 HSNSD PF12062.8 CBY39528.1 - 7.2e-100 335.0 4.7 1.1e-99 334.5 4.7 1.3 1 0 0 1 1 1 1 heparan sulfate-N-deacetylase Sulfotransfer_1 PF00685.27 CBY39528.1 - 5.8e-24 85.0 0.0 1.6e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY39528.1 - 1e-05 26.0 0.0 0.00066 20.1 0.0 2.6 1 1 1 2 2 2 1 Sulfotransferase family EMC3_TMCO1 PF01956.16 CBY39529.1 - 1e-47 162.0 0.1 1.4e-47 161.6 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Glyco_hydro_9 PF00759.19 CBY39535.1 - 1.2e-117 393.8 1.6 1.6e-117 393.5 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF2130 PF09903.9 CBY39538.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF753 PF05444.12 CBY39538.1 - 0.5 10.3 8.0 1.1 9.2 1.0 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF753) SART-1 PF03343.13 CBY39541.1 - 1.8e-61 208.5 49.1 9.4e-61 206.2 49.1 1.8 1 1 0 1 1 1 1 SART-1 family RecX PF02631.16 CBY39541.1 - 2.5 8.6 13.0 0.67 10.4 1.8 3.8 3 0 0 3 3 3 0 RecX family Rhodanese PF00581.20 CBY39544.1 - 2.4e-06 28.0 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain PBP1_TM PF14812.6 CBY39544.1 - 0.027 14.8 2.0 0.093 13.1 2.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_1 PF00561.20 CBY39545.1 - 3.9e-20 72.6 0.2 1.3e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CBY39545.1 - 1.3e-19 69.5 0.1 2.5e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CBY39545.1 - 1.4e-10 40.9 0.0 1.8e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBY39545.1 - 0.00042 21.0 0.0 0.00071 20.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CBY39545.1 - 0.0037 17.1 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 CBY39545.1 - 0.077 12.8 0.0 0.85 9.4 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family TPR_7 PF13176.6 CBY39546.1 - 0.00087 19.1 2.0 0.86 9.8 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBY39546.1 - 0.0011 18.9 1.2 12 6.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY39546.1 - 0.01 16.1 1.2 5.6 7.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY39546.1 - 0.027 14.7 0.5 19 5.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY39546.1 - 0.037 13.9 0.1 1.6 8.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Mt_ATP-synt_D PF05873.12 CBY39546.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) zf-C3HC4_3 PF13920.6 CBY39549.1 - 9.5e-11 41.4 8.9 1.2e-10 41.0 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY39549.1 - 1.3e-08 34.5 10.7 2e-08 34.0 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY39549.1 - 2e-08 34.0 13.1 7.9e-08 32.1 6.4 2.1 1 1 1 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY39549.1 - 2.9e-08 33.4 10.9 4.2e-08 32.9 10.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY39549.1 - 5e-07 29.6 7.8 9.1e-07 28.8 7.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY39549.1 - 7.3e-07 29.0 7.2 1.5e-06 27.9 7.4 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY39549.1 - 1e-06 29.0 10.0 1.4e-06 28.5 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY39549.1 - 0.00074 19.8 9.2 0.0016 18.7 9.2 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY39549.1 - 0.00084 19.4 2.6 0.0011 18.9 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 CBY39549.1 - 0.0013 18.1 4.2 0.0014 18.0 4.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.6 CBY39549.1 - 0.012 15.4 2.2 0.017 15.0 2.2 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY39549.1 - 0.035 13.7 5.2 0.049 13.3 5.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBY39549.1 - 0.036 14.2 9.2 0.1 12.7 9.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING IBR PF01485.21 CBY39549.1 - 0.099 12.9 13.2 0.11 12.7 5.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 CBY39549.1 - 0.18 12.1 7.5 2.3 8.5 4.5 2.8 2 1 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 CBY39549.1 - 0.47 10.3 14.1 3.3 7.6 14.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PolC_DP2 PF03833.13 CBY39549.1 - 0.54 8.1 4.6 0.53 8.1 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zn_Tnp_IS1595 PF12760.7 CBY39549.1 - 1.4 8.9 10.9 1.7e+02 2.3 5.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-Nse PF11789.8 CBY39549.1 - 3.3 7.6 9.0 6.2 6.7 9.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_4 PF13894.6 CBY39549.1 - 4.9 8.3 9.7 7.9 7.6 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 CBY39549.1 - 5.6 7.0 13.7 3.7 7.6 0.1 3.4 2 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 CBY39549.1 - 5.7 7.0 9.8 67 3.6 9.8 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_5 PF13909.6 CBY39552.1 - 0.00018 21.2 4.8 0.00018 21.2 4.8 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CBY39552.1 - 0.011 16.1 5.7 0.011 16.1 5.7 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type CRM1_repeat_2 PF18784.1 CBY39552.1 - 0.078 12.6 0.7 0.22 11.2 0.7 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 CUE PF02845.16 CBY39553.1 - 1 9.1 2.9 3.9 7.3 0.1 3.0 3 0 0 3 3 3 0 CUE domain BTB_2 PF02214.22 CBY39555.1 - 1.1e-10 41.7 0.3 2.1e-10 40.8 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY39555.1 - 1.3e-08 34.4 2.2 1.3e-08 34.4 2.2 2.1 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CBY39555.1 - 9.2e-08 31.9 4.6 9.2e-08 31.9 4.6 1.8 2 0 0 2 2 2 1 Ion channel TMEM43 PF07787.12 CBY39555.1 - 0.77 9.1 4.1 0.61 9.4 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 EF-hand_1 PF00036.32 CBY39556.1 - 3.9e-17 60.4 4.0 1.1e-06 27.8 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBY39556.1 - 4.1e-17 62.4 1.5 8.3e-08 32.6 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY39556.1 - 6.1e-16 56.9 1.2 4.3e-06 26.2 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY39556.1 - 4.9e-13 48.7 4.9 2e-06 27.5 0.2 4.3 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY39556.1 - 1.4e-10 40.2 4.3 0.00022 20.6 0.1 3.3 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 CBY39556.1 - 0.00067 19.6 1.8 0.05 13.6 0.1 3.0 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY39556.1 - 0.015 15.6 0.1 0.92 9.9 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 CBY39556.1 - 0.061 13.5 0.0 19 5.4 0.0 2.8 2 2 1 3 3 3 0 EF hand EF-hand_3 PF09069.11 CBY39556.1 - 0.15 12.5 0.2 0.57 10.6 0.1 2.0 2 1 0 2 2 2 0 EF-hand Collagen PF01391.18 CBY39558.1 - 1.5e-64 213.6 315.8 2.6e-07 30.3 38.1 10.2 3 2 5 8 8 8 6 Collagen triple helix repeat (20 copies) Ets PF00178.22 CBY39559.1 - 7.3e-15 55.2 0.2 1.2e-14 54.5 0.2 1.3 1 0 0 1 1 1 1 Ets-domain HMG_box_2 PF09011.10 CBY39559.1 - 0.059 14.0 0.6 0.099 13.3 0.0 1.7 2 1 0 2 2 2 0 HMG-box domain Myosin_head PF00063.21 CBY39562.1 - 1.1e-262 873.2 1.8 5.3e-262 871.0 1.8 2.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY39562.1 - 5.9e-151 504.5 257.5 7.6e-151 504.2 257.5 1.0 1 0 0 1 1 1 1 Myosin tail Myosin_N PF02736.19 CBY39562.1 - 0.085 12.7 1.1 0.31 10.9 1.1 2.0 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.27 CBY39562.1 - 0.14 12.1 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_22 PF13401.6 CBY39562.1 - 0.16 12.2 0.0 0.16 12.2 0.0 5.1 6 1 0 6 6 6 0 AAA domain AAA_16 PF13191.6 CBY39562.1 - 0.42 11.0 0.0 0.42 11.0 0.0 6.7 2 1 1 3 3 3 0 AAA ATPase domain HSBP1 PF06825.12 CBY39562.1 - 6 6.8 19.7 0.66 9.9 0.4 6.3 6 0 0 6 6 6 0 Heat shock factor binding protein 1 DUF3439 PF11921.8 CBY39563.1 - 1.4 8.9 19.9 1.4 8.9 12.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY39563.1 - 2.8 5.8 3.8 4 5.3 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nuclease_act PF08133.11 CBY39565.1 - 0.5 10.6 3.1 1.2 9.5 3.1 1.5 1 0 0 1 1 1 0 Anticodon nuclease activator family Sugar_tr PF00083.24 CBY39566.1 - 8.6e-29 100.7 24.6 1.2e-28 100.2 24.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY39566.1 - 7.3e-21 74.5 27.9 7.3e-21 74.5 27.9 2.4 3 0 0 3 3 3 1 Major Facilitator Superfamily UCR_6-4kD PF08997.10 CBY39566.1 - 0.003 17.5 3.4 0.16 11.9 0.3 4.2 4 0 0 4 4 4 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Dimer_Tnp_hAT PF05699.14 CBY39568.1 - 1.6e-07 31.0 0.2 2.9e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Trypsin PF00089.26 CBY39572.1 - 4.9e-48 163.8 0.9 5.3e-27 95.1 0.8 2.3 2 0 0 2 2 2 2 Trypsin Kringle PF00051.18 CBY39572.1 - 4.1e-23 81.5 6.4 4.8e-23 81.3 3.5 2.4 2 0 0 2 2 2 1 Kringle domain Integrase_DNA PF02920.15 CBY39573.1 - 0.25 11.1 0.6 0.52 10.0 0.6 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Nnf1 PF03980.14 CBY39574.1 - 0.11 12.9 0.5 0.11 12.9 0.5 1.5 2 0 0 2 2 2 0 Nnf1 COesterase PF00135.28 CBY39575.1 - 1.2e-66 225.6 0.0 1.9e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY39575.1 - 0.00095 19.1 0.1 0.0045 16.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ThiF PF00899.21 CBY39577.1 - 1.2e-20 74.0 0.0 3.1e-20 72.6 0.0 1.7 1 1 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 CBY39577.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CBY39577.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WW PF00397.26 CBY39578.1 - 7.7e-07 29.1 0.4 2.1e-06 27.7 0.4 1.8 1 0 0 1 1 1 1 WW domain Sdh5 PF03937.16 CBY39578.1 - 0.13 12.2 3.7 0.54 10.3 0.3 2.9 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase UPF0016 PF01169.19 CBY39579.1 - 1.7e-42 143.6 23.7 4.4e-21 75.0 5.9 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 GRP PF07172.11 CBY39579.1 - 5.8 7.7 5.6 0.67 10.7 0.7 2.0 2 0 0 2 2 2 0 Glycine rich protein family FbpA PF05833.11 CBY39580.1 - 8e-15 54.5 0.0 8.7e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3788 PF12663.7 CBY39580.1 - 0.11 12.5 0.1 2.7 8.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3788) ABC2_membrane PF01061.24 CBY39581.1 - 1.9e-40 138.5 24.7 2.9e-40 137.9 24.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY39581.1 - 4.1e-22 79.2 0.1 6.4e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CBY39581.1 - 1.3e-05 25.0 1.3 8.2e-05 22.4 0.1 2.6 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 CBY39581.1 - 2.2e-05 24.4 1.0 4.1e-05 23.6 0.5 1.6 2 0 0 2 2 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CBY39581.1 - 0.00015 21.0 23.0 0.00027 20.2 19.7 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein Dynamin_N PF00350.23 CBY39581.1 - 0.00059 19.9 0.4 0.0036 17.4 0.4 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBY39581.1 - 0.00079 19.5 0.9 0.0029 17.7 0.3 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY39581.1 - 0.001 19.3 0.1 0.0076 16.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 CBY39581.1 - 0.0016 18.3 0.6 0.12 12.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBY39581.1 - 0.0059 16.3 1.9 0.015 15.1 0.6 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CBY39581.1 - 0.012 15.7 0.3 0.025 14.7 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 CBY39581.1 - 0.012 15.1 0.4 0.084 12.3 0.3 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBY39581.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CBY39581.1 - 0.04 12.9 0.1 0.082 11.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IIGP PF05049.13 CBY39581.1 - 0.045 12.8 0.2 0.077 12.0 0.2 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 CBY39581.1 - 0.057 13.1 0.0 0.14 11.8 0.1 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CBY39581.1 - 0.067 13.6 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBY39581.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CBY39581.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin PRK PF00485.18 CBY39581.1 - 0.08 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBY39581.1 - 0.098 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3392 PF11872.8 CBY39581.1 - 0.3 11.4 6.7 0.097 12.9 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3392) Lectin_C PF00059.21 CBY39582.1 - 2.9e-77 256.4 31.3 8.2e-17 61.9 0.2 7.6 7 0 0 7 7 7 6 Lectin C-type domain F5_F8_type_C PF00754.25 CBY39582.1 - 5e-24 84.8 0.5 1.6e-17 63.8 0.1 3.5 3 0 0 3 3 3 2 F5/8 type C domain LCCL PF03815.19 CBY39582.1 - 6.2e-16 58.3 0.8 1.9e-15 56.8 0.8 1.8 1 0 0 1 1 1 1 LCCL domain fn2 PF00040.19 CBY39582.1 - 5.4e-06 26.6 4.4 3.1e-05 24.2 4.4 2.5 1 0 0 1 1 1 1 Fibronectin type II domain UL45 PF05473.12 CBY39582.1 - 0.014 15.1 6.9 0.29 10.8 0.1 3.9 5 0 0 5 5 5 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-CCHC_2 PF13696.6 CBY39583.1 - 5.3e-13 48.5 17.3 6.2e-10 38.7 2.3 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC PF00098.23 CBY39583.1 - 2.8e-07 30.3 14.0 0.027 14.5 2.3 3.5 3 0 0 3 3 3 3 Zinc knuckle Tmemb_cc2 PF10267.9 CBY39583.1 - 0.0021 17.3 0.8 0.0033 16.6 0.8 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein zf-CCHC_3 PF13917.6 CBY39583.1 - 0.0023 17.9 12.7 0.008 16.1 0.7 2.9 2 1 0 2 2 2 1 Zinc knuckle EAP30 PF04157.16 CBY39583.1 - 0.024 14.0 0.3 0.76 9.0 0.1 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family HAUS6_N PF14661.6 CBY39583.1 - 0.081 12.5 1.9 0.15 11.6 1.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SKA2 PF16740.5 CBY39583.1 - 0.17 11.7 4.3 0.39 10.5 4.3 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF16 PF01519.16 CBY39583.1 - 0.23 11.9 2.2 0.87 10.1 2.2 2.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 CBY39583.1 - 0.26 9.1 1.2 0.4 8.5 1.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_HK97_TLTM PF06120.11 CBY39583.1 - 0.38 9.9 12.0 0.069 12.3 5.2 2.6 3 0 0 3 3 3 0 Tail length tape measure protein TMPIT PF07851.13 CBY39583.1 - 1.6 7.9 3.4 3.2 6.9 3.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein zf-CCHC_4 PF14392.6 CBY39583.1 - 6.9 6.5 10.2 11 5.9 0.2 3.3 2 1 1 3 3 3 0 Zinc knuckle rRNA_processing PF08524.11 CBY39583.1 - 9.8 6.2 15.2 0.41 10.7 9.0 1.8 2 0 0 2 2 2 0 rRNA processing RVT_1 PF00078.27 CBY39584.1 - 1.3e-17 64.1 1.0 2.2e-17 63.4 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY39584.1 - 1.4e-12 47.9 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CBY39584.1 - 2.1e-08 34.1 0.0 3.8e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY39584.1 - 5.7e-08 33.0 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Baculo_PEP_N PF04512.12 CBY39584.1 - 0.0085 16.4 0.3 0.096 13.0 0.0 2.9 4 0 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, N terminus Integrase_H2C2 PF17921.1 CBY39584.1 - 0.011 15.9 1.9 0.026 14.6 1.9 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CBY39585.1 - 4.4e-14 52.7 0.0 6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY39585.1 - 4.4e-09 36.6 0.1 7.4e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY39585.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY39585.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CBY39585.1 - 0.0021 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CBY39585.1 - 0.02 15.6 0.0 0.03 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBY39585.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ zf-RING_2 PF13639.6 CBY39586.1 - 2.7e-12 46.8 5.0 3.7e-12 46.4 5.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY39586.1 - 8.5e-09 35.3 7.3 1.1e-08 34.9 1.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.12 CBY39586.1 - 4.2e-08 32.9 2.2 5.6e-08 32.5 2.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 CBY39586.1 - 1.2e-07 31.5 5.9 2e-07 30.7 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CBY39586.1 - 1.3e-06 28.4 0.5 1.5e-06 28.2 0.5 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 CBY39586.1 - 1.8e-06 27.7 5.4 3e-06 27.0 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY39586.1 - 2.5e-06 27.2 4.2 3.9e-06 26.6 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY39586.1 - 2.7e-06 27.2 5.7 4.4e-06 26.6 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY39586.1 - 1.9e-05 24.4 6.8 0.00027 20.7 2.0 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CBY39586.1 - 2.2e-05 24.1 5.6 9.6e-05 22.0 1.6 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY39586.1 - 7.8e-05 22.7 4.0 0.00024 21.2 4.1 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY39586.1 - 0.00012 22.2 6.5 0.0005 20.3 6.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 CBY39586.1 - 0.00053 19.8 2.5 0.00097 18.9 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CBY39586.1 - 0.00057 19.9 4.0 0.0009 19.3 4.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CENP-F_leu_zip PF10473.9 CBY39586.1 - 0.00075 19.5 1.5 0.001 19.1 1.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pellino PF04710.14 CBY39586.1 - 0.0008 18.2 1.8 0.0017 17.1 1.8 1.5 1 1 0 1 1 1 1 Pellino MutS_IV PF05190.18 CBY39586.1 - 0.00094 19.5 0.4 0.0013 19.1 0.4 1.1 1 0 0 1 1 1 1 MutS family domain IV zf-C3HC4_5 PF17121.5 CBY39586.1 - 0.0025 17.7 3.9 0.03 14.2 1.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ABC_tran_CTD PF16326.5 CBY39586.1 - 0.0041 17.3 2.4 0.0065 16.7 2.4 1.3 1 0 0 1 1 1 1 ABC transporter C-terminal domain GAS PF13851.6 CBY39586.1 - 0.0069 15.8 1.0 0.0089 15.4 1.0 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Zn_ribbon_17 PF17120.5 CBY39586.1 - 0.0089 15.6 2.8 0.013 15.1 2.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBY39586.1 - 0.009 15.8 3.6 0.017 14.9 3.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DMPK_coil PF08826.10 CBY39586.1 - 0.012 15.7 3.3 0.022 14.8 3.3 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like zf-Sec23_Sec24 PF04810.15 CBY39586.1 - 0.012 15.6 0.5 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Takusan PF04822.13 CBY39586.1 - 0.019 14.8 0.3 0.026 14.4 0.3 1.3 1 0 0 1 1 1 0 Takusan MAD PF05557.13 CBY39586.1 - 0.02 13.3 1.5 0.025 13.0 1.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein zf-RING_10 PF16685.5 CBY39586.1 - 0.025 14.7 3.5 0.043 13.9 3.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 FlaC_arch PF05377.11 CBY39586.1 - 0.041 14.3 0.6 0.069 13.5 0.6 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_C39 PF03412.15 CBY39586.1 - 0.053 13.3 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase C39 family Herpes_BLRF2 PF05812.12 CBY39586.1 - 0.054 13.6 0.4 0.078 13.1 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein YacG PF03884.14 CBY39586.1 - 0.056 13.2 0.9 2.3 8.0 0.2 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Zn-C2H2_12 PF18112.1 CBY39586.1 - 0.076 13.5 3.7 9 6.9 0.1 3.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Uds1 PF15456.6 CBY39586.1 - 0.08 13.1 1.3 0.12 12.5 1.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Zn-ribbon_8 PF09723.10 CBY39586.1 - 0.089 12.9 3.5 1.1 9.4 1.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain YdjO PF14169.6 CBY39586.1 - 0.19 11.5 1.7 2.5 7.9 0.1 2.4 2 1 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_6 PF14835.6 CBY39586.1 - 0.2 11.5 2.6 0.55 10.2 2.6 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 CBY39586.1 - 0.33 10.9 4.3 1.3 9.0 0.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CBY39586.1 - 0.35 11.0 3.5 1.4 9.1 3.5 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger TF_Zn_Ribbon PF08271.12 CBY39586.1 - 0.45 10.1 4.3 2.1 7.9 0.6 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding FANCL_C PF11793.8 CBY39586.1 - 0.85 9.8 7.3 11 6.3 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C6H2 PF15801.5 CBY39586.1 - 0.86 10.0 8.1 3.4 8.0 1.9 2.5 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding MMR_HSR1_C PF08438.10 CBY39587.1 - 0.097 13.2 4.9 0.26 11.9 4.9 1.8 1 0 0 1 1 1 0 GTPase of unknown function C-terminal DUF1993 PF09351.10 CBY39587.1 - 1.7 8.7 8.3 0.73 10.0 5.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Exonuc_VII_L PF02601.15 CBY39587.1 - 2 7.9 15.7 2.8 7.4 15.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 CBY39587.1 - 4.9 6.4 20.8 0.8 9.0 11.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SRP-alpha_N PF04086.13 CBY39587.1 - 7.9 6.3 19.5 6.1 6.7 14.8 1.9 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Peptidase_C48 PF02902.19 CBY39589.1 - 8.5e-11 42.1 4.8 9.8e-05 22.3 1.6 2.6 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_130 PF04041.13 CBY39590.1 - 0.21 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase TSP_1 PF00090.19 CBY39591.1 - 9.5e-34 115.4 78.3 1.1e-10 41.5 6.1 6.1 5 1 0 5 5 5 5 Thrombospondin type 1 domain VWA PF00092.28 CBY39591.1 - 1.4e-12 48.2 0.0 2.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain FXa_inhibition PF14670.6 CBY39591.1 - 0.021 15.1 9.0 0.021 15.1 9.0 5.7 6 0 0 6 6 6 0 Coagulation Factor Xa inhibitory site zf-CCCH PF00642.24 CBY39591.1 - 0.12 12.3 3.8 12 6.0 0.6 3.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Septin PF00735.18 CBY39592.1 - 7.3e-112 373.2 0.0 7.3e-112 373.2 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CBY39592.1 - 1.1e-06 28.6 0.1 3.7e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY39592.1 - 2.5e-05 24.3 1.3 9.8e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CBY39592.1 - 0.00024 20.5 0.0 0.00024 20.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CBY39592.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Ras family GTP_EFTU PF00009.27 CBY39592.1 - 0.014 15.0 3.3 0.36 10.3 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBY39592.1 - 0.017 15.5 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY39592.1 - 0.027 14.8 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBY39592.1 - 0.043 14.0 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CBY39592.1 - 0.14 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 CBY39592.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 CBY39592.1 - 0.98 9.4 13.8 2 8.5 0.0 3.6 2 2 1 3 3 3 0 Dynamin family Prominin PF05478.11 CBY39592.1 - 2.8 5.8 10.6 3.6 5.4 10.6 1.1 1 0 0 1 1 1 0 Prominin DUF2884 PF11101.8 CBY39593.1 - 0.0011 18.5 8.9 0.0011 18.5 8.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) SKA1 PF07160.12 CBY39593.1 - 0.0042 17.0 3.7 0.0042 17.0 3.7 2.2 1 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 GAS PF13851.6 CBY39593.1 - 0.0045 16.4 2.0 0.0045 16.4 2.0 3.3 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding CCDC92 PF14916.6 CBY39593.1 - 0.016 14.9 1.3 0.016 14.9 1.3 3.6 3 1 0 4 4 4 0 Coiled-coil domain of unknown function ATP-synt_F6 PF05511.11 CBY39593.1 - 0.34 11.4 2.7 2.2 8.8 0.1 3.1 1 1 2 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 MAD PF05557.13 CBY39593.1 - 1.3 7.3 36.9 0.89 7.8 15.0 2.7 1 1 1 2 2 2 0 Mitotic checkpoint protein CHASE6_C PF17150.4 CBY39593.1 - 4.8 7.9 6.5 5.6 7.7 1.1 3.3 2 2 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain ZapB PF06005.12 CBY39593.1 - 6.5 7.3 34.9 1.2 9.6 1.0 4.3 4 1 1 5 5 5 0 Cell division protein ZapB IBN_N PF03810.19 CBY39595.1 - 7.4e-16 57.8 0.6 1.2e-13 50.7 0.0 3.3 3 0 0 3 3 3 2 Importin-beta N-terminal domain DUF3385 PF11865.8 CBY39595.1 - 0.25 11.2 2.6 1.6 8.6 0.1 3.1 1 1 0 3 3 3 0 Domain of unknown function (DUF3385) Xpo1 PF08389.12 CBY39595.1 - 0.72 9.9 15.5 0.51 10.4 1.1 4.6 4 1 1 5 5 5 0 Exportin 1-like protein An_peroxidase PF03098.15 CBY39599.1 - 1.8e-58 198.4 0.0 2.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase zf-P11 PF03854.14 CBY39599.1 - 0.16 11.6 0.9 0.38 10.4 0.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger ABC_tran PF00005.27 CBY39601.1 - 1.8e-23 83.5 0.0 3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY39601.1 - 1.1e-12 47.7 31.7 1.5e-12 47.3 31.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CBY39601.1 - 9.9e-11 42.0 0.0 1.1e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY39601.1 - 4.6e-05 24.0 0.0 8.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBY39601.1 - 7.9e-05 22.5 0.0 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBY39601.1 - 0.00055 19.9 0.1 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CBY39601.1 - 0.00063 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4162 PF13732.6 CBY39601.1 - 0.00072 20.2 0.1 0.0013 19.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 CBY39601.1 - 0.0052 16.2 0.0 0.085 12.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 CBY39601.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBY39601.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 CBY39601.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBY39601.1 - 0.074 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBY39601.1 - 0.076 13.3 0.1 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CBY39601.1 - 0.079 12.8 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal ABC2_membrane_2 PF12679.7 CBY39601.1 - 7.8 5.7 15.7 12 5.1 15.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF3_subunit PF08597.10 CBY39603.1 - 0.0031 17.5 16.0 0.005 16.8 16.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Med26 PF08711.11 CBY39603.1 - 0.011 15.7 0.3 0.067 13.2 0.0 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DNA_pol_E_B PF04042.16 CBY39603.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B HV_small_capsid PF17086.5 CBY39603.1 - 1.3 9.3 5.7 3.8 7.9 0.6 2.9 1 1 0 2 2 2 0 Small capsid protein of Herpesviridae BRCT PF00533.26 CBY39604.1 - 6.5e-14 52.1 0.2 2.4e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBY39604.1 - 5.3e-13 48.7 0.0 2.7e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 CBY39604.1 - 5.5e-13 49.1 0.1 2e-11 44.1 0.1 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY39604.1 - 0.00015 22.0 0.0 0.00059 20.1 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain IATP PF04568.12 CBY39604.1 - 2.6 8.5 5.6 1.8 9.1 2.0 2.5 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Use1 PF09753.9 CBY39605.1 - 3.9 7.1 12.3 1.5 8.5 3.2 2.6 2 1 0 2 2 2 0 Membrane fusion protein Use1 WD40 PF00400.32 CBY39606.1 - 6.2e-13 49.0 11.4 0.0063 17.3 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY39606.1 - 0.02 13.9 1.0 3.4 6.5 0.4 3.7 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YqgF PF14639.6 CBY39606.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 STATa_Ig PF18214.1 CBY39606.1 - 0.18 11.8 0.9 0.32 11.0 0.9 1.3 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain PAP_assoc PF03828.19 CBY39607.1 - 7e-14 51.8 0.0 1.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY39607.1 - 1.5e-11 44.4 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY39607.1 - 0.003 17.6 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase 7tm_2 PF00002.24 CBY39608.1 - 2.6e-07 30.2 12.1 1.3e-06 27.9 12.1 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Somatomedin_B PF01033.17 CBY39609.1 - 1.4e-06 28.6 12.7 1.4e-06 28.6 12.7 3.1 3 0 0 3 3 3 1 Somatomedin B domain TSP_1 PF00090.19 CBY39609.1 - 0.02 15.1 10.1 0.02 15.1 10.1 2.6 2 1 0 2 2 2 0 Thrombospondin type 1 domain Adeno_E3_CR2 PF02439.15 CBY39611.1 - 0.0051 16.5 1.0 0.0085 15.8 1.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 BatA PF07584.11 CBY39611.1 - 0.021 15.2 1.4 0.12 12.8 0.8 2.0 1 1 2 3 3 3 0 Aerotolerance regulator N-terminal Stevor PF17410.2 CBY39611.1 - 0.025 14.1 0.2 0.025 14.1 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 CBY39611.1 - 0.025 14.5 0.5 0.025 14.5 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 CBY39611.1 - 0.034 12.9 0.0 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Chordopox_L2 PF05803.12 CBY39611.1 - 0.036 13.9 3.9 0.048 13.5 3.9 1.1 1 0 0 1 1 1 0 Chordopoxvirus L2 protein ODV-E18 PF10717.9 CBY39611.1 - 0.046 13.6 0.8 0.06 13.2 0.8 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 CBY39611.1 - 0.049 14.5 2.2 0.082 13.8 2.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CBY39611.1 - 0.066 13.5 0.2 0.075 13.3 0.2 1.2 1 0 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 CBY39611.1 - 0.14 12.0 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Rifin RCR PF12273.8 CBY39611.1 - 0.71 10.5 3.0 1.2 9.8 3.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ac76 PF05814.11 CBY39611.1 - 0.83 9.7 6.9 1.2 9.1 6.9 1.5 1 1 0 1 1 1 0 Orf76 (Ac76) Comm PF15957.5 CBY39611.1 - 0.96 9.8 3.7 1.1 9.6 3.4 1.3 1 1 0 1 1 1 0 Commissureless TMEMspv1-c74-12 PF11044.8 CBY39613.1 - 8.9 6.4 7.9 0.39 10.7 2.5 1.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4407 PF14362.6 CBY39614.1 - 0.094 12.1 5.5 0.14 11.5 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 CBY39614.1 - 0.77 9.8 21.3 1.5 8.8 16.2 2.6 1 1 1 2 2 2 0 FlxA-like protein Exonuc_VII_L PF02601.15 CBY39614.1 - 2 7.9 8.1 2.6 7.5 8.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GH114_assoc PF14741.6 CBY39615.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain PFU PF09070.11 CBY39615.1 - 0.16 12.3 0.1 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Pkinase_Tyr PF07714.17 CBY39616.1 - 4.8e-37 127.6 0.0 6.5e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY39616.1 - 6e-19 68.4 0.0 8.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 CBY39616.1 - 3.7e-15 56.0 0.0 1.7e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 Fibronectin type III domain Ephrin_rec_like PF07699.13 CBY39616.1 - 0.0022 17.7 6.5 0.0022 17.7 6.5 2.8 2 1 1 3 3 3 1 Putative ephrin-receptor like Pur_ac_phosph_N PF16656.5 CBY39616.1 - 0.0066 17.0 0.0 7.1 7.3 0.0 2.6 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain Sdh_cyt PF01127.22 CBY39616.1 - 0.06 13.4 0.6 0.14 12.2 0.3 1.7 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PTS_EIIA_1 PF00358.20 CBY39616.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RVT_1 PF00078.27 CBY39619.1 - 1.6e-22 80.1 0.0 3.4e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRF_C1 PF13887.6 CBY39620.1 - 0.088 12.0 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Na_Pi_cotrans PF02690.15 CBY39622.1 - 4.1e-13 49.6 10.7 1.8e-12 47.5 10.5 2.2 1 1 0 1 1 1 1 Na+/Pi-cotransporter Sigma_reg_N PF13800.6 CBY39622.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.1 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Adeno_E3_CR2 PF02439.15 CBY39623.1 - 0.038 13.8 1.3 0.061 13.1 1.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TPR_1 PF00515.28 CBY39624.1 - 0.015 15.1 0.9 0.015 15.1 0.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY39624.1 - 0.1 12.8 3.9 0.26 11.5 0.8 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY39625.1 - 4.4e-11 42.1 4.8 0.00044 19.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY39625.1 - 9.5e-10 37.8 3.6 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBY39625.1 - 1.2e-06 28.7 0.0 0.08 13.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY39625.1 - 6.8e-06 25.9 5.4 0.00027 20.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY39625.1 - 4.9e-05 23.7 0.0 0.013 16.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 CBY39625.1 - 0.00018 22.1 0.3 0.0015 19.1 0.1 2.7 1 1 1 2 2 2 1 Sel1 repeat TPR_16 PF13432.6 CBY39625.1 - 0.0002 21.9 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39625.1 - 0.0074 16.5 0.1 2.2 8.6 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY39625.1 - 0.0094 16.3 0.0 0.55 10.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY39625.1 - 0.012 15.6 0.3 0.86 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3919 PF13057.6 CBY39625.1 - 0.014 15.0 0.7 0.026 14.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) MIT PF04212.18 CBY39625.1 - 0.02 14.9 1.6 3.8 7.7 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CBY39625.1 - 0.024 15.1 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY39625.1 - 0.028 14.1 3.1 0.22 11.2 1.6 2.8 2 1 0 2 2 2 0 TPR repeat DUF4446 PF14584.6 CBY39625.1 - 0.051 13.6 0.4 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) O-FucT PF10250.9 CBY39626.1 - 0.012 15.4 0.1 0.024 14.3 0.1 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Aa_trans PF01490.18 CBY39628.1 - 1e-10 40.9 5.7 1.3e-10 40.6 5.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Monooxygenase_B PF04744.12 CBY39628.1 - 0.037 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein Aa_trans PF01490.18 CBY39629.1 - 6.7e-19 67.9 17.6 3.3e-12 45.8 4.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein HGTP_anticodon PF03129.20 CBY39630.1 - 2.9e-09 36.9 0.0 3.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain DUF3492 PF11997.8 CBY39631.1 - 0.071 12.8 1.3 0.093 12.5 0.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) RFX_DNA_binding PF02257.15 CBY39633.1 - 0.011 16.3 0.1 0.019 15.6 0.1 1.3 1 0 0 1 1 1 0 RFX DNA-binding domain DnaB PF00772.21 CBY39633.1 - 0.1 12.7 0.2 0.19 11.8 0.2 1.5 1 1 0 1 1 1 0 DnaB-like helicase N terminal domain LAMTOR5 PF16672.5 CBY39634.1 - 0.092 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 ATP-synt_ab_N PF02874.23 CBY39635.1 - 4.1e-13 49.6 0.3 5.5e-13 49.2 0.3 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 CBY39635.1 - 0.03 14.5 0.3 0.041 14.0 0.3 1.4 1 1 0 1 1 1 0 HAS barrel domain TPR_2 PF07719.17 CBY39636.1 - 3.5e-10 39.2 1.0 0.00082 19.3 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY39636.1 - 3.3e-08 33.1 0.0 0.0027 17.4 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.28 CBY39636.1 - 5.6e-07 29.1 1.6 0.016 15.0 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY39636.1 - 8.8e-05 23.0 0.3 0.9 10.5 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY39636.1 - 9.9e-05 22.9 0.2 0.23 12.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY39636.1 - 0.00026 20.9 0.4 0.51 10.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY39636.1 - 0.0019 18.3 0.5 1.1 9.5 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY39636.1 - 0.0029 18.1 0.5 0.9 10.1 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39636.1 - 0.0069 16.6 1.1 0.43 10.8 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CBY39636.1 - 0.013 15.8 1.4 2.1 8.7 0.3 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY39636.1 - 0.013 15.8 3.7 0.032 14.6 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY39636.1 - 0.019 14.0 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Pneumo_M2 PF07380.11 CBY39636.1 - 0.048 13.9 0.2 9.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Pneumovirus M2 protein TPR_6 PF13174.6 CBY39636.1 - 0.1 13.3 0.1 35 5.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat U-box PF04564.15 CBY39637.1 - 2.8e-25 88.3 0.1 5.2e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 CBY39637.1 - 7.7e-19 68.3 11.0 7.7e-19 68.3 11.0 2.0 2 0 0 2 2 2 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 CBY39637.1 - 1.8e-13 49.5 5.9 0.0021 18.0 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY39637.1 - 1.2e-12 47.1 3.6 0.0002 21.0 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39637.1 - 2.6e-10 40.4 1.7 4.8e-10 39.5 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CBY39637.1 - 2e-07 31.4 0.4 0.0083 16.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY39637.1 - 2.5e-07 31.3 0.1 0.0012 19.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY39637.1 - 4e-07 29.6 2.2 0.00026 20.6 0.3 3.0 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY39637.1 - 1.7e-05 25.0 3.8 0.18 12.1 0.0 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY39637.1 - 2.6e-05 24.3 0.0 0.15 12.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY39637.1 - 6.7e-05 22.8 11.9 0.15 12.4 0.1 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY39637.1 - 0.00024 21.6 2.3 3.2 8.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY39637.1 - 0.00079 20.1 0.3 1.9 9.5 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 CBY39637.1 - 0.0014 17.7 0.2 0.0019 17.2 0.2 1.3 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) zf-NOSIP PF15906.5 CBY39637.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SRP_TPR_like PF17004.5 CBY39637.1 - 0.11 12.5 8.1 3.2 7.8 0.1 3.3 1 1 2 3 3 3 0 Putative TPR-like repeat Tn7_Tnp_TnsA_C PF08721.11 CBY39637.1 - 0.37 11.5 2.7 0.58 10.8 0.5 2.5 2 1 1 3 3 2 0 TnsA endonuclease C terminal DUF1053 PF06327.14 CBY39641.1 - 0.043 14.4 0.9 0.16 12.5 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) ABC_tran PF00005.27 CBY39643.1 - 1.8e-30 106.3 0.3 2.5e-30 105.8 0.3 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY39643.1 - 1.9e-06 27.9 1.0 0.0041 17.0 0.3 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY39643.1 - 2e-06 27.4 5.0 0.01 15.3 0.2 2.7 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CBY39643.1 - 0.00011 22.4 0.2 0.00025 21.2 0.2 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain Rad17 PF03215.15 CBY39643.1 - 0.00025 21.0 0.2 0.33 10.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_29 PF13555.6 CBY39643.1 - 0.00054 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY39643.1 - 0.0015 18.6 0.6 0.0046 17.0 0.5 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CBY39643.1 - 0.002 18.4 0.3 0.0098 16.2 0.3 1.9 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 CBY39643.1 - 0.0064 15.8 0.1 0.0095 15.3 0.1 1.2 1 0 0 1 1 1 1 AIG1 family AAA_23 PF13476.6 CBY39643.1 - 0.0068 16.9 1.4 0.014 15.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CBY39643.1 - 0.0078 15.6 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.13 CBY39643.1 - 0.015 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 CBY39643.1 - 0.018 14.8 0.3 0.024 14.4 0.3 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CBY39643.1 - 0.018 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY39643.1 - 0.02 14.1 0.1 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 CBY39643.1 - 0.029 14.1 0.0 0.14 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBY39643.1 - 0.042 13.7 0.0 0.088 12.7 0.0 1.6 2 0 0 2 2 1 0 RsgA GTPase AAA_10 PF12846.7 CBY39643.1 - 0.048 12.6 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 CBY39643.1 - 0.054 13.9 0.1 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CBY39643.1 - 0.12 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CBY39643.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_membrane PF00664.23 CBY39644.1 - 1.2e-39 136.6 26.7 4.6e-20 72.4 5.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY39644.1 - 5.3e-20 72.3 0.0 9.9e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY39644.1 - 4.2e-06 26.3 0.2 0.0067 15.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Yip1 PF04893.17 CBY39644.1 - 0.0085 15.8 0.4 0.0085 15.8 0.4 3.7 5 1 0 5 5 5 1 Yip1 domain Zeta_toxin PF06414.12 CBY39644.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 CBY39644.1 - 0.02 14.8 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CBY39644.1 - 0.039 13.7 0.3 0.084 12.6 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY39644.1 - 0.082 13.4 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY39644.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBY39644.1 - 0.1 12.7 0.3 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dimer_Tnp_hAT PF05699.14 CBY39645.1 - 1.6e-07 31.0 0.2 2.9e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tweety PF04906.13 CBY39647.1 - 0.03 13.0 0.4 0.04 12.6 0.4 1.1 1 0 0 1 1 1 0 Tweety Shisa PF13908.6 CBY39647.1 - 0.073 13.3 0.1 0.076 13.3 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sigma_reg_N PF13800.6 CBY39647.1 - 0.2 12.0 1.8 0.38 11.1 1.8 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal EF_TS PF00889.19 CBY39648.1 - 0.024 14.3 1.3 0.32 10.6 0.5 1.9 1 1 1 2 2 2 0 Elongation factor TS EF-G-binding_N PF07299.11 CBY39648.1 - 0.13 12.8 2.8 1.3 9.6 1.1 2.2 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DUF2681 PF10883.8 CBY39648.1 - 0.26 11.7 3.1 0.41 11.1 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) UPF0242 PF06785.11 CBY39649.1 - 0.00067 19.8 12.0 0.018 15.1 0.3 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 CBY39649.1 - 0.00099 19.5 19.1 0.024 15.1 3.5 3.2 3 0 0 3 3 3 1 Cell division protein ZapB LMBR1 PF04791.16 CBY39649.1 - 0.013 14.5 4.7 0.015 14.3 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 CBY39649.1 - 0.019 14.6 21.0 0.11 12.1 8.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NRBF2 PF08961.10 CBY39649.1 - 0.024 14.2 1.6 0.024 14.2 1.6 2.7 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator IFP_35_N PF07334.13 CBY39649.1 - 0.03 14.4 0.4 0.03 14.4 0.4 3.2 3 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF848 PF05852.11 CBY39649.1 - 0.048 13.8 0.2 0.048 13.8 0.2 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) APG6_N PF17675.1 CBY39649.1 - 0.068 13.7 17.3 0.15 12.6 10.7 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region Siah-Interact_N PF09032.11 CBY39649.1 - 0.072 13.4 0.8 0.072 13.4 0.8 2.8 2 1 0 2 2 2 0 Siah interacting protein, N terminal CENP-F_leu_zip PF10473.9 CBY39649.1 - 0.073 13.1 17.1 0.5 10.4 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 CBY39649.1 - 0.076 13.3 7.7 0.18 12.0 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.9 CBY39649.1 - 0.09 12.7 17.6 0.078 12.9 7.7 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF1192 PF06698.11 CBY39649.1 - 0.12 12.4 3.3 0.15 12.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Fungal_TACC PF12709.7 CBY39649.1 - 0.14 12.6 15.7 0.26 11.8 2.2 3.2 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins UPF0449 PF15136.6 CBY39649.1 - 0.15 12.5 9.6 0.5 10.9 4.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 FapA PF03961.13 CBY39649.1 - 0.16 10.5 12.1 0.26 9.9 3.4 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DivIC PF04977.15 CBY39649.1 - 0.23 11.3 20.0 1.2 9.0 3.4 3.6 3 1 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 CBY39649.1 - 0.24 11.5 20.0 0.077 13.1 2.2 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 CBY39649.1 - 0.26 11.3 10.2 1.5 8.9 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CBY39649.1 - 0.31 11.4 9.5 7.3 7.1 0.7 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 CBY39649.1 - 0.45 10.5 10.0 1.8 8.5 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) FRG PF08867.11 CBY39649.1 - 0.97 10.4 8.1 2.7 9.0 0.8 3.0 2 1 1 3 3 3 0 FRG domain Mto2_bdg PF12808.7 CBY39649.1 - 0.99 9.7 13.1 0.69 10.3 0.7 3.3 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4094 PF13334.6 CBY39649.1 - 1.1 9.8 4.6 1.4 9.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF5082 PF16888.5 CBY39649.1 - 1.2 9.5 13.8 0.69 10.2 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) HMMR_C PF15908.5 CBY39649.1 - 1.4 9.2 15.3 0.09 13.0 6.7 2.8 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 CBY39649.1 - 2.4 8.8 16.6 0.45 11.2 3.4 3.2 2 1 1 3 3 3 0 Initiation control protein YabA DivIVA PF05103.13 CBY39649.1 - 3.3 7.8 16.5 0.52 10.4 3.8 3.1 2 1 1 3 3 3 0 DivIVA protein Spc24 PF08286.11 CBY39649.1 - 5.8 7.2 20.0 3.6 7.9 2.6 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 CBY39649.1 - 5.8 6.2 10.4 9.4 5.5 8.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 CBY39649.1 - 9 6.7 16.6 0.11 12.9 2.5 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF724 PF05266.14 CBY39649.1 - 9.9 5.9 16.5 7.1 6.4 6.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) LRR_8 PF13855.6 CBY39650.1 - 3.1e-59 196.6 17.1 4.7e-17 61.5 0.2 4.3 2 1 5 7 7 7 6 Leucine rich repeat I-set PF07679.16 CBY39650.1 - 2e-16 59.8 0.0 4.6e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin I-set domain LRR_4 PF12799.7 CBY39650.1 - 1.5e-14 53.8 8.2 2.2e-06 27.9 1.1 5.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) Ig_3 PF13927.6 CBY39650.1 - 2.1e-14 53.9 0.6 1e-13 51.6 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain LRR_5 PF13306.6 CBY39650.1 - 7.6e-14 51.8 0.1 2e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Ig_2 PF13895.6 CBY39650.1 - 3e-08 33.9 0.6 1.3e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CBY39650.1 - 8.9e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY39650.1 - 3.2e-07 30.5 0.2 1.9e-05 24.8 0.1 3.3 2 1 0 2 2 2 1 Immunoglobulin V-set domain LRR_1 PF00560.33 CBY39650.1 - 2.4e-06 27.3 0.2 4.9 8.1 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 CBY39650.1 - 2.9e-05 23.7 6.0 0.0041 16.6 0.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRRNT PF01462.18 CBY39650.1 - 0.012 15.3 4.8 0.04 13.6 4.8 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain TPR_21 PF09976.9 CBY39650.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain ABC2_membrane_3 PF12698.7 CBY39653.1 - 4.6e-23 81.9 25.2 6.2e-23 81.5 25.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 CBY39653.1 - 7.5e-23 81.6 0.0 1.2e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY39653.1 - 1.3e-12 48.1 0.5 6.2e-09 36.1 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY39653.1 - 9.7e-05 21.9 0.0 0.09 12.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CBY39653.1 - 0.0038 17.9 0.1 0.015 16.0 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 CBY39653.1 - 0.0045 17.5 1.3 0.0071 16.9 0.4 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY39653.1 - 0.0048 16.6 0.2 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBY39653.1 - 0.014 15.1 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 CBY39653.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TTL PF03133.15 CBY39654.1 - 1.3e-68 231.3 0.1 3.5e-68 229.9 0.1 1.7 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY39654.1 - 1e-07 31.5 0.3 1.4e-05 24.4 0.1 2.8 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBY39654.1 - 0.041 13.1 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Ntox46 PF15538.6 CBY39654.1 - 0.042 13.8 0.1 0.086 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 46 OstA PF03968.14 CBY39654.1 - 0.062 13.5 1.0 0.22 11.7 0.6 2.2 1 1 0 1 1 1 0 OstA-like protein Fibrinogen_C PF00147.18 CBY39655.1 - 1.2e-40 139.7 17.7 6.6e-29 101.3 10.0 4.0 2 2 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain Fib_alpha PF08702.10 CBY39655.1 - 1.9e-05 24.9 0.0 4.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Ig_3 PF13927.6 CBY39656.1 - 2.9e-11 43.8 0.2 2.4e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Immunoglobulin domain TSP_1 PF00090.19 CBY39656.1 - 4.6e-11 42.8 10.4 4.6e-11 42.8 10.4 2.9 3 2 2 5 5 5 1 Thrombospondin type 1 domain Ig_2 PF13895.6 CBY39656.1 - 2.3e-10 40.7 0.6 4.4e-08 33.3 0.0 2.9 2 1 1 3 3 3 1 Immunoglobulin domain I-set PF07679.16 CBY39656.1 - 3.4e-09 36.7 0.1 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin I-set domain CarboxypepD_reg PF13620.6 CBY39656.1 - 2e-08 34.4 0.0 4.6e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain ig PF00047.25 CBY39656.1 - 8.6e-08 32.3 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain CarbopepD_reg_2 PF13715.6 CBY39656.1 - 8.3e-07 28.9 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 CarboxypepD_reg-like domain V-set PF07686.17 CBY39656.1 - 3e-06 27.3 0.6 0.0014 18.7 0.0 3.0 2 1 1 3 3 3 1 Immunoglobulin V-set domain HypA PF01155.19 CBY39656.1 - 0.35 10.9 8.8 1.1 9.3 8.8 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ig_3 PF13927.6 CBY39657.1 - 3.7e-22 78.7 0.7 8.4e-05 23.1 0.0 5.7 5 1 0 5 5 5 5 Immunoglobulin domain ig PF00047.25 CBY39657.1 - 2e-18 66.3 4.9 5e-05 23.4 0.1 6.6 5 2 0 5 5 5 3 Immunoglobulin domain Ig_2 PF13895.6 CBY39657.1 - 1e-15 57.8 0.1 0.00049 20.4 0.1 5.4 5 1 0 5 5 5 2 Immunoglobulin domain I-set PF07679.16 CBY39657.1 - 3.1e-14 52.8 2.4 0.0035 17.4 0.0 7.0 6 2 0 6 6 6 3 Immunoglobulin I-set domain Laminin_G_2 PF02210.24 CBY39657.1 - 3.9e-14 53.3 0.1 6.8e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain V-set PF07686.17 CBY39657.1 - 7.4e-11 42.2 0.3 5.2e-06 26.6 0.0 4.7 4 1 1 5 5 5 1 Immunoglobulin V-set domain Ig_4 PF16680.5 CBY39657.1 - 4e-10 39.8 1.2 0.00029 21.0 0.1 4.0 4 0 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Ig_5 PF16681.5 CBY39657.1 - 7e-10 39.2 2.9 0.00089 19.6 0.1 3.9 4 1 1 5 5 4 2 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Laminin_G_1 PF00054.23 CBY39657.1 - 3.1e-08 33.9 0.1 2.5e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 Laminin G domain Ig_6 PF18452.1 CBY39657.1 - 4.1e-05 23.0 0.1 0.45 10.1 0.0 3.8 4 0 0 4 4 4 2 Immunoglobulin domain Izumo-Ig PF16706.5 CBY39657.1 - 0.00094 19.2 0.0 0.8 9.8 0.0 3.7 3 0 0 3 3 3 1 Izumo-like Immunoglobulin domain CBM_14 PF01607.24 CBY39658.1 - 5.3e-13 48.9 4.3 6.6e-13 48.6 3.8 1.6 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain 7tm_1 PF00001.21 CBY39659.1 - 1.6e-15 57.2 0.6 1.7e-15 57.1 0.6 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 CBY39659.1 - 0.042 13.2 0.5 0.05 13.0 0.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx Sec3_C PF09763.9 CBY39660.1 - 0.14 10.5 3.3 0.19 10.0 3.3 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec3 BTD PF09270.10 CBY39661.1 - 4.2e-65 218.7 0.0 1.1e-64 217.3 0.0 1.7 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.11 CBY39661.1 - 2.4e-46 158.1 0.2 5.4e-46 157.0 0.2 1.6 1 0 0 1 1 1 1 LAG1, DNA binding Ins145_P3_rec PF08709.11 CBY39661.1 - 0.06 12.5 0.1 0.62 9.2 0.1 2.2 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF1836 PF08876.11 CBY39663.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Peptidase_S49_N PF08496.10 CBY39663.1 - 0.14 12.2 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ion_trans PF00520.31 CBY39664.1 - 0.079 12.2 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein TRAM_LAG1_CLN8 PF03798.16 CBY39668.1 - 2.6e-13 50.2 3.5 3.2e-13 49.9 3.5 1.1 1 0 0 1 1 1 1 TLC domain Cation_efflux PF01545.21 CBY39668.1 - 0.027 14.2 0.3 0.56 9.9 0.3 2.1 1 1 0 1 1 1 0 Cation efflux family LacI PF00356.21 CBY39669.1 - 0.032 14.0 0.9 0.11 12.4 0.9 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family APP_Cu_bd PF12924.7 CBY39670.1 - 1.6e-18 67.2 3.5 2.8e-18 66.4 3.5 1.4 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD APP_amyloid PF10515.9 CBY39670.1 - 5.2e-13 49.3 0.1 2.6e-12 47.0 0.1 2.1 2 0 0 2 2 2 1 Beta-amyloid precursor protein C-terminus TMEM51 PF15345.6 CBY39670.1 - 0.0043 16.9 1.2 0.0059 16.5 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 51 Mucin PF01456.17 CBY39670.1 - 0.063 13.3 30.1 0.15 12.0 30.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein KAR9 PF08580.10 CBY39670.1 - 0.44 9.0 2.6 0.49 8.9 2.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Dicty_REP PF05086.12 CBY39670.1 - 0.97 7.3 6.9 1.1 7.1 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CcmD PF04995.14 CBY39670.1 - 3.9 7.6 6.8 9.3 6.4 6.8 1.6 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) WH2 PF02205.20 CBY39672.1 - 7.5e-06 25.6 0.1 2e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 WH2 motif Caleosin PF05042.13 CBY39673.1 - 0.01 15.8 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Caleosin related protein DUF16 PF01519.16 CBY39673.1 - 0.037 14.5 1.8 0.058 13.9 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 IF4E PF01652.18 CBY39674.1 - 5.1e-49 166.1 0.4 6.4e-49 165.8 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF5507 PF17612.2 CBY39676.1 - 0.084 12.6 0.2 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5507) YlbD_coat PF14071.6 CBY39676.1 - 0.38 11.0 3.1 1.1 9.5 0.1 2.6 3 0 0 3 3 3 0 Putative coat protein Kinesin PF00225.23 CBY39677.1 - 6e-60 202.9 0.1 6.7e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY39677.1 - 1.9e-27 96.0 0.1 2.9e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 CBY39678.1 - 3e-22 78.5 10.5 0.0073 17.1 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CBY39678.1 - 3.8e-10 39.4 11.0 3.8e-10 39.4 11.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY39678.1 - 2.4e-08 33.7 9.8 8.5e-08 32.0 9.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY39678.1 - 1.3e-07 31.3 7.9 3.5e-07 30.0 7.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 CBY39678.1 - 1.8e-07 31.3 2.3 1.5 9.1 1.3 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_UBOX PF13445.6 CBY39678.1 - 2.3e-07 30.7 8.9 6.5e-07 29.3 8.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger WD40_like PF17005.5 CBY39678.1 - 5.4e-07 29.2 0.8 6.5e-05 22.4 0.0 2.8 2 1 1 3 3 3 1 WD40-like domain zf-RING_5 PF14634.6 CBY39678.1 - 6.2e-07 29.3 10.6 6.2e-07 29.3 10.6 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 CBY39678.1 - 1.4e-06 28.3 5.9 4.8e-06 26.6 5.9 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CBY39678.1 - 1.5e-06 28.4 10.7 1.5e-06 28.4 10.7 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBY39678.1 - 3.1e-05 24.0 9.3 9.7e-05 22.4 9.3 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CBY39678.1 - 8.1e-05 22.4 3.2 0.00016 21.5 3.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY39678.1 - 0.00024 20.9 10.0 0.00056 19.7 10.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 UNC-79 PF14776.6 CBY39678.1 - 0.0057 15.5 3.2 0.0093 14.8 3.2 1.2 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 DUF5026 PF16429.5 CBY39678.1 - 0.048 13.8 0.1 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) zf-P11 PF03854.14 CBY39678.1 - 0.29 10.8 5.8 0.85 9.3 5.8 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 CBY39678.1 - 1.8 8.4 6.3 6.3 6.7 6.3 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CBY39678.1 - 5.1 7.5 15.4 0.69 10.3 7.4 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain PHD PF00628.29 CBY39679.1 - 2.2e-07 30.6 12.6 1.2e-06 28.3 13.2 1.7 1 1 1 2 2 2 1 PHD-finger C1_1 PF00130.22 CBY39679.1 - 0.0095 15.8 8.2 0.0095 15.8 8.2 2.1 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CBY39679.1 - 0.095 12.8 10.4 0.28 11.3 10.5 1.9 1 1 1 2 2 2 0 KIAA1045 RING finger DUF3088 PF11287.8 CBY39679.1 - 0.22 11.3 2.0 8.9 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) zf-RING_9 PF13901.6 CBY39679.1 - 0.51 10.3 10.6 1.7 8.5 10.6 1.8 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Zn_ribbon_17 PF17120.5 CBY39679.1 - 2 8.1 12.5 7.6 6.2 12.5 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type HscB_4_cys PF18256.1 CBY39679.1 - 4 7.4 10.7 0.76 9.6 0.3 2.4 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Collagen PF01391.18 CBY39680.1 - 2e-42 142.7 170.7 3e-09 36.5 24.6 6.3 3 1 2 5 5 5 5 Collagen triple helix repeat (20 copies) EXS PF03124.14 CBY39681.1 - 6.8e-33 114.4 7.4 7.7e-33 114.2 7.4 1.0 1 0 0 1 1 1 1 EXS family CH PF00307.31 CBY39682.1 - 1.3e-15 57.5 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.18 CBY39682.1 - 6.3e-13 48.1 3.5 6.3e-13 48.1 3.5 1.9 2 0 0 2 2 2 1 Calponin family repeat CDC24 PF06395.11 CBY39682.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 CBY39682.1 - 0.016 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Sulfatase PF00884.23 CBY39683.1 - 1.1e-57 195.8 0.7 1.5e-57 195.4 0.7 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY39683.1 - 1.3e-05 25.0 0.1 0.00031 20.4 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 CBY39683.1 - 0.057 12.5 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) DUF4994 PF16385.5 CBY39683.1 - 0.15 12.0 0.4 0.59 10.1 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function Osmo_CC PF08946.10 CBY39684.1 - 0.064 13.5 4.1 0.15 12.4 4.0 1.7 1 1 0 1 1 1 0 Osmosensory transporter coiled coil Syntaxin-6_N PF09177.11 CBY39684.1 - 0.068 13.7 1.5 0.093 13.3 1.5 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Chlam_OMP3 PF03503.13 CBY39684.1 - 0.17 12.2 4.6 0.29 11.5 4.6 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Alpha-E PF04168.12 CBY39684.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. DUF4665 PF15679.5 CBY39684.1 - 0.19 12.4 3.8 0.29 11.8 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) YabA PF06156.13 CBY39684.1 - 5.3 7.7 9.7 0.7 10.6 1.1 2.2 2 0 0 2 2 2 0 Initiation control protein YabA AAA_8 PF12780.7 CBY39686.1 - 5e-99 330.8 0.0 1.1e-98 329.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBY39686.1 - 1.6e-94 316.6 0.3 4.6e-94 315.1 0.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 CBY39686.1 - 2.6e-64 217.4 11.8 8.8e-30 103.9 0.3 4.1 3 1 2 5 5 5 3 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 CBY39686.1 - 2.8e-37 126.9 0.8 1.3e-36 124.7 0.3 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_9 PF12781.7 CBY39686.1 - 5.6e-33 113.9 4.1 3.3e-15 55.8 0.0 3.6 1 1 2 3 3 3 3 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CBY39686.1 - 2.7e-26 92.3 0.4 6.8e-23 81.3 0.0 3.3 2 1 1 3 3 3 2 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 CBY39686.1 - 2.4e-25 89.1 0.1 1.7e-24 86.4 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBY39686.1 - 9.7e-20 70.8 0.0 2.2e-18 66.5 0.0 3.1 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CBY39686.1 - 0.011 15.7 0.0 0.094 12.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATG16 PF08614.11 CBY39687.1 - 0.0044 17.3 8.9 0.0044 17.3 8.9 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 CBY39687.1 - 0.16 12.0 13.8 0.031 14.4 9.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1043 PF06295.12 CBY39687.1 - 0.21 11.6 7.5 0.73 9.8 7.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4047 PF13256.6 CBY39687.1 - 0.5 10.6 9.4 0.078 13.2 4.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) LTXXQ PF07813.12 CBY39687.1 - 2.3 9.0 7.5 0.12 13.1 1.2 2.2 2 1 1 3 3 3 0 LTXXQ motif family protein APG6_N PF17675.1 CBY39687.1 - 3.4 8.2 20.4 0.22 12.1 4.0 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 CBY39687.1 - 5.8 6.1 10.4 0.5 9.6 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ING PF12998.7 CBY39687.1 - 9.5 6.9 10.3 3.9 8.1 6.5 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2457 PF10446.9 CBY39688.1 - 0.021 14.0 13.4 0.026 13.7 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vps23_core PF09454.10 CBY39688.1 - 0.026 14.5 0.2 0.051 13.5 0.2 1.4 1 0 0 1 1 1 0 Vps23 core domain DUF1841 PF08897.11 CBY39688.1 - 0.09 12.8 0.8 0.18 11.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) TraH PF06122.11 CBY39688.1 - 0.33 10.2 4.8 0.39 9.9 4.8 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein RP-C_C PF11800.8 CBY39688.1 - 0.45 10.6 5.2 0.6 10.2 5.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1168 PF06658.12 CBY39688.1 - 0.78 9.6 16.4 0.58 10.0 14.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Nop14 PF04147.12 CBY39688.1 - 3.7 5.6 18.3 4 5.5 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family DnaJ_CXXCXGXG PF00684.19 CBY39689.1 - 4.5e-05 23.7 18.3 0.00031 21.1 19.0 2.1 1 1 1 2 2 2 2 DnaJ central domain Coiled PF05710.12 CBY39689.1 - 0.14 13.0 4.5 2.6 8.9 0.2 2.2 1 1 1 2 2 2 0 Coiled coil I-EGF_1 PF18372.1 CBY39689.1 - 0.26 11.4 19.9 1.8 8.7 5.0 2.4 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 DUF1356 PF07092.12 CBY39689.1 - 0.31 10.3 6.6 2 7.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) PRR20 PF15708.5 CBY39689.1 - 2.1 8.2 4.1 2 8.3 3.5 1.3 1 1 0 1 1 1 0 Proline-rich protein family 20 Anti-TRAP PF15777.5 CBY39689.1 - 3.9 7.5 16.5 1.1 9.3 2.5 3.5 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein bZIP_1 PF00170.21 CBY39690.1 - 1.3e-09 38.0 7.7 2.5e-09 37.1 7.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY39690.1 - 3.1e-07 30.4 13.5 3.3e-07 30.3 10.3 2.6 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY39690.1 - 3.8e-05 24.1 5.6 8.8e-05 23.0 5.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF5082 PF16888.5 CBY39690.1 - 0.025 14.9 0.8 0.025 14.9 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 CBY39690.1 - 0.067 13.1 1.6 0.15 12.0 1.6 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 CBY39690.1 - 8.3 6.3 8.4 0.33 10.8 1.0 2.2 2 1 1 3 3 3 0 Septum formation initiator Na_sulph_symp PF00939.19 CBY39692.1 - 7.4e-73 246.2 9.9 1.1e-72 245.7 9.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBY39692.1 - 4e-30 105.1 17.4 3.2e-17 62.7 5.2 2.1 2 0 0 2 2 2 2 Citrate transporter 7TM_GPCR_Srz PF10325.9 CBY39692.1 - 0.0083 15.5 1.1 0.0083 15.5 1.1 2.6 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srz HEAT_2 PF13646.6 CBY39694.1 - 1e-06 29.0 1.3 5.2e-06 26.8 0.9 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CBY39694.1 - 0.00017 21.6 0.7 1.9 9.0 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 CBY39694.1 - 0.0006 20.3 5.3 0.23 12.0 0.0 3.9 4 0 0 4 4 4 2 HEAT-like repeat ChapFlgA PF13144.6 CBY39696.1 - 2.8 8.0 9.1 1.5 8.9 3.9 2.4 1 1 2 3 3 3 0 Chaperone for flagella basal body P-ring formation Phospholip_A2_1 PF00068.19 CBY39698.1 - 4e-11 43.4 10.6 4e-11 43.4 10.6 2.2 2 0 0 2 2 2 1 Phospholipase A2 Dicty_REP PF05086.12 CBY39699.1 - 0.18 9.8 14.4 0.29 9.1 14.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.8 CBY39699.1 - 0.21 10.3 1.0 0.35 9.6 1.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRCC PF10253.9 CBY39699.1 - 8.8 7.1 9.5 17 6.1 9.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Glyco_hydro_47 PF01532.20 CBY39701.1 - 1.5e-94 317.5 0.0 3.9e-94 316.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 CBY39701.1 - 0.016 14.7 0.3 1.9 8.0 0.0 2.9 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus PA PF02225.22 CBY39702.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PA domain DUF1681 PF07933.14 CBY39702.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Meckelin PF09773.9 CBY39703.1 - 3.1e-182 607.8 4.9 3.1e-182 607.8 4.9 1.8 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) EGF_MSP1_1 PF12946.7 CBY39703.1 - 0.073 13.1 2.0 0.2 11.8 2.0 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 BaffR-Tall_bind PF09256.10 CBY39703.1 - 0.58 10.0 6.1 0.29 10.9 2.1 2.5 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Leo1 PF04004.13 CBY39704.1 - 4.4e-35 121.0 0.1 4.4e-35 121.0 0.1 1.7 2 0 0 2 2 2 1 Leo1-like protein SOBP PF15279.6 CBY39705.1 - 8.9 6.8 9.6 12 6.5 9.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAP2 PF01569.21 CBY39706.1 - 8.8e-29 100.0 0.3 4.6e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily Tmemb_161AB PF10268.9 CBY39706.1 - 0.11 11.1 0.3 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB PAP2_C PF14360.6 CBY39706.1 - 0.16 12.5 1.1 1 9.9 1.1 2.2 1 1 0 1 1 1 0 PAP2 superfamily C-terminal CCDC53 PF10152.9 CBY39708.1 - 0.0066 16.9 0.4 0.0066 16.9 0.4 2.2 1 1 1 2 2 2 1 Subunit CCDC53 of WASH complex O-FucT PF10250.9 CBY39711.1 - 0.00013 21.8 0.0 0.00068 19.4 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TetR_C_8 PF14278.6 CBY39711.1 - 0.012 15.7 0.2 0.047 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Nipped-B_C PF12830.7 CBY39712.1 - 1.6e-13 51.0 1.7 2e-13 50.7 0.1 1.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus DUF5009 PF16401.5 CBY39713.1 - 5.9e-08 32.5 5.1 6.2e-07 29.2 0.2 3.3 3 1 0 3 3 3 2 Domain of unknown function (DUF5009) DUF1624 PF07786.12 CBY39713.1 - 2.4e-06 27.3 0.9 2.4e-06 27.3 0.9 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1624) Profilin PF00235.19 CBY39714.1 - 1.3e-20 73.9 0.1 1.5e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 Profilin Kelch_6 PF13964.6 CBY39716.1 - 2.4e-08 33.9 0.8 0.017 15.4 0.2 3.7 3 1 1 4 4 4 2 Kelch motif zf-RING_5 PF14634.6 CBY39716.1 - 3.6e-06 26.8 19.7 3.6e-06 26.8 19.7 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Kelch_4 PF13418.6 CBY39716.1 - 8.9e-06 25.6 0.6 1.2 9.3 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY39716.1 - 2.2e-05 24.3 0.4 1.2 9.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif zf-RING_2 PF13639.6 CBY39716.1 - 3e-05 24.3 18.9 3e-05 24.3 18.9 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_4 PF14570.6 CBY39716.1 - 0.0013 18.5 15.6 0.0013 18.5 15.6 2.1 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain Kelch_3 PF13415.6 CBY39716.1 - 0.0051 17.1 0.5 9.7 6.6 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBY39716.1 - 0.011 15.3 0.2 4.7 6.9 0.1 3.3 3 0 0 3 3 3 0 Kelch motif zf-RING_UBOX PF13445.6 CBY39716.1 - 0.017 15.2 15.3 0.017 15.2 15.3 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY39716.1 - 0.052 13.4 20.4 0.15 12.0 20.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.15 CBY39716.1 - 0.11 12.6 0.5 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif DUF3504 PF12012.8 CBY39716.1 - 0.53 10.2 4.1 0.83 9.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) DUF724 PF05266.14 CBY39716.1 - 0.57 10.0 8.6 0.94 9.3 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Actin PF00022.19 CBY39717.1 - 4.2e-147 490.0 0.0 1.4e-146 488.3 0.0 1.7 1 1 0 1 1 1 1 Actin IMUP PF15761.5 CBY39719.1 - 0.035 14.8 6.2 0.039 14.7 6.2 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Hepatitis_core PF00906.20 CBY39719.1 - 0.52 9.8 7.1 0.56 9.7 7.1 1.2 1 0 0 1 1 1 0 Hepatitis core antigen DUF755 PF05501.11 CBY39719.1 - 1.1 9.5 15.0 1.4 9.2 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2457 PF10446.9 CBY39719.1 - 3.8 6.6 11.1 4.6 6.3 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sec7 PF01369.20 CBY39720.1 - 2.1e-23 82.9 1.0 3.1e-23 82.4 1.0 1.2 1 0 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 CBY39720.1 - 0.0064 16.4 0.8 0.014 15.3 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CBY39720.1 - 0.085 12.8 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 CBY39720.1 - 0.089 13.1 0.1 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 PRANC domain ABC_tran PF00005.27 CBY39721.1 - 1.1e-12 48.6 0.1 1.5e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY39721.1 - 2.8e-05 24.1 0.2 3.7e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CBY39721.1 - 0.0002 21.4 0.1 0.00039 20.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY39721.1 - 0.0018 18.7 0.0 0.0023 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY39721.1 - 0.002 18.4 0.1 0.0028 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 CBY39721.1 - 0.0021 18.2 0.5 0.0043 17.2 0.5 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 CBY39721.1 - 0.0022 17.7 0.3 0.0054 16.5 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBY39721.1 - 0.0055 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Septin PF00735.18 CBY39721.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 CBY39721.1 - 0.012 15.9 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY39721.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBY39721.1 - 0.015 14.3 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 CBY39721.1 - 0.017 14.9 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 CBY39721.1 - 0.021 14.9 0.3 0.096 12.7 0.1 2.0 1 1 1 2 2 2 0 Dynamin family AAA_24 PF13479.6 CBY39721.1 - 0.023 14.4 0.1 0.039 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBY39721.1 - 0.027 14.4 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 CBY39721.1 - 0.038 14.5 0.1 0.059 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CBY39721.1 - 0.041 13.8 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 CBY39721.1 - 0.05 12.8 0.3 0.062 12.5 0.3 1.3 1 1 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CBY39721.1 - 0.051 12.6 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CBY39721.1 - 0.063 13.0 0.5 0.083 12.6 0.4 1.3 1 1 0 1 1 1 0 AAA domain GBP PF02263.19 CBY39721.1 - 0.066 12.5 0.1 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain cobW PF02492.19 CBY39721.1 - 0.073 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBY39721.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBY39721.1 - 0.34 11.4 0.3 0.34 11.4 0.3 2.3 2 1 1 3 3 3 0 AAA domain ABC2_membrane PF01061.24 CBY39722.1 - 5.2e-36 124.0 23.4 7.4e-36 123.5 23.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CBY39722.1 - 4.4e-07 29.3 10.6 8.6e-07 28.4 9.7 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 CBY39722.1 - 0.018 14.9 0.3 0.018 14.9 0.3 2.9 3 0 0 3 3 3 0 CDR ABC transporter AAA_21 PF13304.6 CBY39722.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3392 PF11872.8 CBY39722.1 - 1 9.7 4.3 0.93 9.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Aminotran_1_2 PF00155.21 CBY39723.1 - 3e-28 99.1 0.0 4.9e-28 98.3 0.0 1.3 1 1 1 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CBY39723.1 - 3.4e-18 65.7 0.0 4.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 CBY39723.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CBY39723.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PROCN PF08083.11 CBY39724.1 - 3.9e-228 757.0 7.6 3.9e-228 757.0 7.6 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CBY39724.1 - 1.4e-126 420.8 0.3 2.6e-126 419.9 0.3 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CBY39724.1 - 4.5e-89 296.4 2.3 1.2e-88 295.1 2.3 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CBY39724.1 - 5.3e-87 289.4 6.1 6.1e-87 289.2 4.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CBY39724.1 - 4.9e-72 240.3 0.0 1e-71 239.2 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CBY39724.1 - 3.5e-46 155.5 0.6 1e-45 154.0 0.6 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 TSP_1 PF00090.19 CBY39726.1 - 7.5e-41 138.1 157.6 1.4e-09 38.0 5.8 12.5 12 2 0 12 12 12 9 Thrombospondin type 1 domain Sulfotransfer_1 PF00685.27 CBY39727.1 - 5.3e-07 29.4 4.5 1.2e-06 28.2 4.5 1.6 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY39727.1 - 0.00068 20.1 0.1 0.0016 18.9 0.1 1.6 1 0 0 1 1 1 1 Sulfotransferase family VKG_Carbox PF05090.14 CBY39731.1 - 1.1e-71 242.0 18.6 1.4e-71 241.6 18.6 1.0 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase FoP_duplication PF13865.6 CBY39732.1 - 9.1e-06 26.1 5.6 9.1e-06 26.1 5.6 2.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RGS-like PF09128.11 CBY39732.1 - 0.093 12.4 3.0 0.15 11.7 3.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Maf1 PF09174.10 CBY39733.1 - 1.8e-46 158.5 0.2 2.3e-46 158.1 0.2 1.2 1 0 0 1 1 1 1 Maf1 regulator RL10P_insert PF17777.1 CBY39734.1 - 1.9e-15 56.6 0.0 2.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBY39734.1 - 2.7e-05 24.2 0.3 7.4e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 EF-hand_1 PF00036.32 CBY39735.1 - 1.5e-26 89.9 13.7 2.9e-06 26.4 0.4 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBY39735.1 - 5.4e-24 84.4 6.1 3.3e-13 49.9 0.7 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY39735.1 - 9.5e-21 71.9 7.5 6.7e-05 22.5 0.4 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY39735.1 - 3.3e-20 70.6 7.8 0.00012 21.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY39735.1 - 7.5e-16 57.7 9.2 3.2e-06 26.9 0.4 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY39735.1 - 1.5e-07 31.7 0.3 0.0072 16.6 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY39735.1 - 1.3e-05 25.0 5.6 0.044 13.7 0.1 3.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBY39735.1 - 0.0053 16.7 4.1 9.3 6.1 0.1 3.8 2 2 2 4 4 4 2 Caleosin related protein Dockerin_1 PF00404.18 CBY39735.1 - 0.02 15.1 2.3 0.36 11.0 0.4 3.1 3 1 1 4 4 4 0 Dockerin type I domain EF-hand_9 PF14658.6 CBY39735.1 - 0.039 14.3 0.4 2.4 8.6 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain SURF2 PF05477.11 CBY39736.1 - 9.2e-33 113.9 7.5 1.2e-32 113.5 7.5 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) DUF5099 PF17025.5 CBY39736.1 - 0.053 13.9 1.3 0.061 13.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) DGCR6 PF07324.11 CBY39736.1 - 0.073 12.7 2.7 0.16 11.6 2.7 1.5 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein RIIa PF02197.17 CBY39737.1 - 0.0065 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit dsrm PF00035.26 CBY39738.1 - 1.2e-33 115.6 0.0 5.8e-16 59.0 0.0 3.4 3 0 0 3 3 3 3 Double-stranded RNA binding motif DND1_DSRM PF14709.7 CBY39738.1 - 4.2e-14 52.6 2.9 5.5e-05 23.3 0.1 4.3 3 2 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 Staufen_C PF16482.5 CBY39738.1 - 5.1e-10 39.5 1.0 3.6e-08 33.5 0.0 2.9 2 1 1 3 3 3 1 Staufen C-terminal domain LPP20 PF02169.16 CBY39738.1 - 0.015 15.7 0.2 4.5 7.7 0.0 2.9 3 0 0 3 3 3 0 LPP20 lipoprotein CPSase_L_D2 PF02786.17 CBY39739.1 - 2.2e-45 154.7 0.0 3.6e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CBY39739.1 - 2.7e-36 124.0 0.0 8.3e-36 122.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CBY39739.1 - 0.00057 19.5 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CBY39739.1 - 0.003 17.3 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.22 CBY39739.1 - 0.02 14.7 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 2 0 Biotin-requiring enzyme tRNA-synt_1c PF00749.21 CBY39740.1 - 4.8e-107 357.5 0.0 7e-107 357.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CBY39740.1 - 2.5e-31 108.8 0.4 2.5e-31 108.8 0.4 1.7 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 CBY39740.1 - 1.3e-22 80.5 3.5 3.2e-22 79.3 3.5 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 tRNA-synt_1c_C PF03950.18 CBY39740.1 - 1.1e-07 31.9 0.1 3.6e-07 30.2 0.1 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain LAGLIDADG_1 PF00961.19 CBY39740.1 - 0.016 16.1 0.4 0.052 14.5 0.4 1.8 1 0 0 1 1 1 0 LAGLIDADG endonuclease PAC3 PF10178.9 CBY39741.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 LRR_8 PF13855.6 CBY39742.1 - 1.7e-15 56.5 49.0 5.8e-07 29.2 8.7 5.1 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 CBY39742.1 - 6.9e-15 54.9 40.9 5.9e-07 29.7 3.4 7.1 2 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY39742.1 - 2.2e-05 24.4 39.8 0.056 14.0 0.6 9.8 9 1 1 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 CBY39742.1 - 0.026 14.5 35.4 1.2 9.3 0.5 9.3 10 0 0 10 10 10 0 Leucine Rich repeat TAF1D PF15333.6 CBY39743.1 - 0.00063 19.5 2.6 0.0011 18.7 2.6 1.4 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D LMBR1 PF04791.16 CBY39745.1 - 6.2e-18 65.0 10.8 6.2e-18 65.0 10.8 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein PDEase_I PF00233.19 CBY39746.1 - 7.3e-32 111.0 0.1 9.6e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Integrin_alpha2 PF08441.12 CBY39747.1 - 1.4e-50 172.5 2.3 1.8e-50 172.2 2.3 1.1 1 0 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY39747.1 - 1.6e-19 69.7 4.7 2.8e-05 24.1 0.1 3.6 3 0 0 3 3 3 3 FG-GAP repeat VCBS PF13517.6 CBY39747.1 - 6.6e-16 58.6 5.6 2.9e-11 43.8 0.4 3.0 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid PF14783.6 CBY39747.1 - 0.028 14.5 0.1 1.4 9.0 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region TraG-D_C PF12696.7 CBY39749.1 - 0.38 10.8 6.2 0.97 9.4 6.2 2.0 1 1 0 1 1 1 0 TraM recognition site of TraD and TraG Noelin-1 PF12308.8 CBY39749.1 - 0.49 10.4 6.2 0.078 13.0 1.5 2.0 2 1 0 2 2 2 0 Neurogenesis glycoprotein zf-C4H2 PF10146.9 CBY39749.1 - 2.1 8.6 18.7 3.6 7.8 18.7 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein APG6_N PF17675.1 CBY39751.1 - 0.00037 21.0 28.4 0.00037 21.0 28.4 4.0 2 1 1 3 3 3 1 Apg6 coiled-coil region GAS PF13851.6 CBY39751.1 - 0.00051 19.4 80.1 0.31 10.4 20.9 3.4 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CBY39751.1 - 0.0028 16.6 76.0 0.24 10.2 16.0 3.2 1 1 2 3 3 3 3 Spc7 kinetochore protein Laminin_II PF06009.12 CBY39751.1 - 0.017 15.1 53.6 0.08 12.9 12.2 4.7 1 1 3 4 4 4 0 Laminin Domain II ATG16 PF08614.11 CBY39751.1 - 0.018 15.3 75.0 0.044 14.0 15.8 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 CBY39751.1 - 0.021 15.2 1.6 0.021 15.2 1.6 5.9 4 2 1 5 5 3 0 Centrosome microtubule-binding domain of Cep57 DUF745 PF05335.13 CBY39751.1 - 0.057 13.1 50.2 0.22 11.2 5.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) LPP PF04728.13 CBY39751.1 - 0.064 13.7 1.5 0.064 13.7 1.5 7.6 4 2 2 7 7 7 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 CBY39751.1 - 0.071 13.2 75.7 0.14 12.2 23.2 4.0 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CBY39751.1 - 0.098 12.3 75.2 0.62 9.7 1.5 4.6 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 CBY39751.1 - 0.11 12.7 26.3 0.48 10.7 1.8 5.2 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 CBY39751.1 - 0.2 11.9 61.9 0.59 10.4 16.4 4.9 1 1 4 5 5 5 0 Flagellar FliJ protein DUF5082 PF16888.5 CBY39751.1 - 0.33 11.2 60.8 0.43 10.9 6.5 4.8 2 2 3 5 5 4 0 Domain of unknown function (DUF5082) FH2 PF02181.23 CBY39751.1 - 0.53 9.3 39.8 0.37 9.9 5.7 3.2 2 1 1 3 3 3 0 Formin Homology 2 Domain T3SSipB PF16535.5 CBY39751.1 - 0.57 10.6 36.0 0.29 11.6 8.1 3.5 1 1 1 3 3 3 0 Type III cell invasion protein SipB Filament PF00038.21 CBY39751.1 - 0.88 9.1 65.9 2 7.9 13.4 3.5 1 1 2 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 CBY39751.1 - 0.97 9.9 67.8 4.3 7.8 21.4 3.4 1 1 2 3 3 3 0 Fez1 FUSC PF04632.12 CBY39751.1 - 1.2 7.5 14.3 2.4 6.6 3.7 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family Alpha-2-MRAP_C PF06401.11 CBY39751.1 - 2.3 8.2 55.4 11 5.9 9.8 3.5 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF4407 PF14362.6 CBY39751.1 - 2.5 7.4 46.0 0.69 9.2 9.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 CBY39751.1 - 3.3 8.2 56.1 0.12 12.9 9.4 5.3 1 1 4 5 5 5 0 Spectrin repeat Atg14 PF10186.9 CBY39751.1 - 6 5.9 62.6 2.8 6.9 27.0 3.4 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHR10 PF18595.1 CBY39751.1 - 6.3 6.9 82.5 0.35 10.9 15.4 6.0 1 1 5 6 6 6 0 Designed helical repeat protein 10 domain EzrA PF06160.12 CBY39751.1 - 6.4 4.8 64.9 3.7 5.6 9.8 3.5 1 1 1 3 3 3 0 Septation ring formation regulator, EzrA CALCOCO1 PF07888.11 CBY39751.1 - 7 5.4 63.8 0.49 9.2 10.4 3.8 1 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.12 CBY39751.1 - 7.1 7.2 31.9 0.48 10.9 1.0 5.5 2 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Pox_A_type_inc PF04508.12 CBY39751.1 - 7.3 6.6 17.7 1.2 9.1 1.4 6.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Taxilin PF09728.9 CBY39751.1 - 8.7 5.4 71.4 17 4.4 37.6 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.7 CBY39751.1 - 8.8 6.5 82.1 1.5 9.0 32.8 4.0 1 1 2 3 3 3 0 Tropomyosin like MFS_1 PF07690.16 CBY39752.1 - 2.4e-05 23.4 10.5 0.00088 18.3 7.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gaa1 PF04114.14 CBY39752.1 - 0.0025 16.9 0.5 0.0027 16.8 0.5 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component LtrA PF06772.11 CBY39752.1 - 0.013 14.8 0.2 0.022 14.0 0.2 1.5 1 1 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) DUF4233 PF14017.6 CBY39752.1 - 0.14 12.5 1.8 0.32 11.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) DUF2456 PF10445.9 CBY39752.1 - 0.42 10.7 6.5 2.3 8.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) CdvA PF18822.1 CBY39753.1 - 0.0038 17.1 7.0 0.0038 17.1 7.0 6.0 3 2 3 6 6 6 2 CdvA-like coiled-coil domain Hrs_helical PF12210.8 CBY39753.1 - 0.031 14.8 1.7 0.031 14.8 1.7 5.2 3 1 0 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Spc7 PF08317.11 CBY39753.1 - 0.04 12.8 71.3 0.021 13.7 23.2 4.7 1 1 3 5 5 5 0 Spc7 kinetochore protein KASH_CCD PF14662.6 CBY39753.1 - 1.3 8.8 71.9 1.4 8.7 1.5 5.1 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 CBY39753.1 - 2.8 8.0 68.2 0.11 12.5 13.5 5.3 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 CBY39753.1 - 4.2 6.8 55.5 1.1 8.7 23.3 2.4 2 0 0 2 2 2 0 Leucine zipper ATP-synt_DE PF00401.20 CBY39753.1 - 6 7.2 11.5 13 6.2 2.3 3.5 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Fib_alpha PF08702.10 CBY39753.1 - 6.3 7.0 41.9 0.45 10.7 7.5 5.0 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 CBY39753.1 - 8 6.4 7.3 14 5.7 0.3 3.9 2 2 2 4 4 4 0 Apolipoprotein O Kinesin PF00225.23 CBY39754.1 - 3.5e-86 289.1 0.0 5.9e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY39754.1 - 4e-22 78.8 0.3 1.7e-19 70.2 0.0 2.8 3 0 0 3 3 3 2 Microtubule binding SHE3 PF17078.5 CBY39754.1 - 0.029 14.1 7.0 0.49 10.1 3.5 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ATPase_2 PF01637.18 CBY39754.1 - 0.098 12.6 0.8 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CBY39754.1 - 0.1 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_MLP1_2 PF07926.12 CBY39754.1 - 0.15 12.2 1.6 0.32 11.1 0.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FCH PF00611.23 CBY39755.1 - 5.9e-08 32.9 0.0 2.7e-07 30.7 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CBY39755.1 - 8.9e-06 25.2 0.1 3.4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CBY39755.1 - 0.00072 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CBY39755.1 - 0.042 14.1 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF725 PF05267.12 CBY39755.1 - 0.064 13.2 12.8 0.36 10.8 0.7 4.7 3 1 0 4 4 4 0 Protein of unknown function (DUF725) Exonuc_VII_L PF02601.15 CBY39755.1 - 2 7.9 15.6 3.9 6.9 3.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit EI24 PF07264.11 CBY39756.1 - 3.1e-19 69.9 11.1 4.3e-19 69.4 11.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Acyl-CoA_dh_M PF02770.19 CBY39759.1 - 3.7e-06 27.1 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain GARS_A PF01071.19 CBY39760.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain C1q PF00386.21 CBY39761.1 - 2.5e-13 50.3 0.0 5.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 C1q domain EGF_CA PF07645.15 CBY39761.1 - 1.8e-06 28.1 6.9 3.5e-06 27.1 6.9 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39761.1 - 0.029 14.5 3.6 0.063 13.5 3.6 1.5 1 0 0 1 1 1 0 EGF domain EGF PF00008.27 CBY39761.1 - 0.23 11.8 7.7 0.49 10.7 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 CBY39761.1 - 0.9 10.3 5.7 1.9 9.3 5.7 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF DUF948 PF06103.11 CBY39761.1 - 3.4 8.0 5.5 2.7 8.3 0.3 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SR-25 PF10500.9 CBY39763.1 - 0.017 14.7 15.6 0.026 14.2 15.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAC2 PF09754.9 CBY39763.1 - 0.13 12.3 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 PAC2 family Herpes_pp85 PF04637.12 CBY39763.1 - 4.1 5.7 7.6 5.8 5.2 7.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TPT PF03151.16 CBY39765.1 - 2.2e-74 250.4 28.8 2.5e-74 250.3 28.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY39765.1 - 1.1e-16 61.2 31.8 2.2e-08 34.4 13.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CBY39765.1 - 2.3e-05 23.8 22.1 2.8e-05 23.5 22.1 1.2 1 0 0 1 1 1 1 UAA transporter family Abhydrolase_1 PF00561.20 CBY39766.1 - 5.6e-15 55.7 0.0 6.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY39766.1 - 1.8e-10 41.8 0.0 2.2e-10 41.5 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBY39766.1 - 6.1e-08 32.2 0.0 1.3e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase PF00151.19 CBY39766.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipase DUF915 PF06028.11 CBY39766.1 - 0.01 15.2 0.1 0.51 9.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 CBY39766.1 - 0.041 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CBY39766.1 - 0.046 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF434 PF04256.12 CBY39766.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Abhydrolase_5 PF12695.7 CBY39766.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CBY39766.1 - 0.15 12.1 0.1 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Histone_H2A_C PF16211.5 CBY39767.1 - 3.1e-17 62.0 0.5 5.8e-17 61.1 0.1 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 CBY39767.1 - 6.1e-10 39.6 0.0 8.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY39767.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sulfotransfer_4 PF17784.1 CBY39768.1 - 3.1e-19 69.7 0.1 3.5e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain AA_permease_2 PF13520.6 CBY39769.1 - 5.4e-55 186.9 30.4 7.4e-55 186.5 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY39769.1 - 1.5e-16 60.1 23.5 2.1e-16 59.6 23.5 1.1 1 0 0 1 1 1 1 Amino acid permease Actin PF00022.19 CBY39770.1 - 1.1e-35 123.1 0.0 1.2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Actin hEGF PF12661.7 CBY39771.1 - 0.099 13.3 3.3 0.099 13.3 3.3 3.4 5 1 0 5 5 5 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY39771.1 - 0.23 11.7 8.8 0.23 11.7 5.3 2.8 2 0 0 2 2 2 0 Calcium-binding EGF domain EGF_2 PF07974.13 CBY39771.1 - 1.8 9.0 9.5 1.8 9.0 5.6 3.0 2 0 0 2 2 2 0 EGF-like domain SpoU_methylase PF00588.19 CBY39772.1 - 7.9e-27 94.2 0.1 1e-26 93.8 0.1 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.6 CBY39772.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Hydrolase PF00702.26 CBY39773.1 - 9.3e-52 176.4 0.6 1.6e-51 175.6 0.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBY39773.1 - 3e-05 23.6 0.4 3e-05 23.6 0.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 CBY39773.1 - 3.2e-05 24.4 0.1 0.00015 22.2 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY39773.1 - 0.0012 18.6 4.9 0.016 15.0 2.1 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 CBY39775.1 - 1.6e-21 75.9 4.4 1.6e-21 75.9 4.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CBY39775.1 - 0.52 10.3 0.1 0.52 10.3 0.1 2.3 2 1 0 2 2 2 0 Homeobox KN domain Peptidase_S31 PF05578.12 CBY39776.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 GAGBD PF16828.5 CBY39777.1 - 0.0029 17.7 0.1 0.0059 16.7 0.1 1.5 1 0 0 1 1 1 1 GAG-binding domain on surface antigen GBP PF02263.19 CBY39777.1 - 0.019 14.2 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain UNC-93 PF05978.16 CBY39778.1 - 3.5e-34 117.8 9.8 5.7e-34 117.1 9.8 1.3 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CBY39778.1 - 0.00023 20.2 11.8 0.00035 19.6 11.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 CBY39778.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.4 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF4405 PF14358.6 CBY39779.1 - 7.2 7.2 9.2 2.5 8.7 2.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Exo_endo_phos PF03372.23 CBY39780.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BATS PF06968.13 CBY39781.1 - 0.009 16.1 0.0 0.058 13.5 0.0 2.2 1 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Methyltr_RsmB-F PF01189.17 CBY39781.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DSPc PF00782.20 CBY39782.1 - 7.8e-28 96.9 0.0 8.9e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBY39782.1 - 0.0011 18.5 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBY39782.1 - 0.0043 17.2 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 CBY39782.1 - 0.0057 16.9 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAP1_N PF04849.13 CBY39783.1 - 1.6e-42 145.8 27.1 2.3e-42 145.3 27.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ERM PF00769.19 CBY39783.1 - 0.001 18.9 13.2 0.001 18.9 13.2 3.5 3 1 0 4 4 4 1 Ezrin/radixin/moesin family Lipoprotein_7 PF01540.16 CBY39783.1 - 0.0071 15.7 5.0 0.0071 15.7 5.0 2.1 2 0 0 2 2 2 1 Adhesin lipoprotein DUF2935 PF11155.8 CBY39783.1 - 0.01 16.2 0.1 0.27 11.6 0.1 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) RasGAP_C PF03836.15 CBY39783.1 - 0.015 15.4 0.2 0.015 15.4 0.2 3.6 3 1 0 3 3 1 0 RasGAP C-terminus Snapin_Pallidin PF14712.6 CBY39783.1 - 0.022 15.2 3.7 0.022 15.2 3.7 3.9 2 1 2 4 4 4 0 Snapin/Pallidin DivIVA PF05103.13 CBY39783.1 - 0.028 14.5 0.2 0.028 14.5 0.2 3.6 3 1 1 4 4 3 0 DivIVA protein Myosin_tail_1 PF01576.19 CBY39783.1 - 0.04 11.7 28.5 0.059 11.2 18.3 2.2 2 0 0 2 2 2 0 Myosin tail GIT_CC PF16559.5 CBY39783.1 - 0.045 13.6 12.0 0.64 9.9 1.6 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 CBY39783.1 - 0.057 13.7 16.6 0.089 13.1 2.4 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family TTRAP PF14203.6 CBY39783.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.5 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DUF5624 PF18538.1 CBY39783.1 - 0.18 11.9 0.5 0.54 10.4 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Fib_alpha PF08702.10 CBY39783.1 - 0.44 10.7 20.7 0.25 11.5 4.4 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CBY39783.1 - 0.8 9.0 18.9 1.6 8.0 15.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBY39783.1 - 0.87 9.6 17.2 4.7 7.3 0.2 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 CBY39783.1 - 0.99 9.4 13.7 0.66 9.9 2.0 3.6 4 1 0 4 4 3 0 Sec20 FAD-SLDH PF12318.8 CBY39783.1 - 1 9.4 6.5 0.64 10.1 0.4 2.7 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Milton PF12448.8 CBY39783.1 - 1.3 9.1 10.4 0.068 13.3 2.6 2.6 2 2 0 2 2 2 0 Kinesin associated protein TMCO5 PF14992.6 CBY39783.1 - 4.3 6.8 24.2 2 7.9 14.0 2.3 2 0 0 2 2 2 0 TMCO5 family Leu_zip PF15294.6 CBY39783.1 - 5.2 6.5 23.0 30 4.0 17.6 2.6 1 1 1 2 2 2 0 Leucine zipper YabA PF06156.13 CBY39783.1 - 6 7.6 24.5 1.6 9.4 0.6 4.4 2 1 1 3 3 2 0 Initiation control protein YabA Herpes_BLRF2 PF05812.12 CBY39783.1 - 6.2 7.0 13.4 0.21 11.7 4.2 3.0 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein Seryl_tRNA_N PF02403.22 CBY39783.1 - 9.3 6.5 25.9 1.1 9.5 3.7 4.6 4 1 2 6 6 5 0 Seryl-tRNA synthetase N-terminal domain 7tm_2 PF00002.24 CBY39784.1 - 2.2e-52 177.8 10.0 3.5e-52 177.2 10.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CBY39784.1 - 5.4e-06 25.8 9.5 1.1e-05 24.7 9.5 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LRRC37AB_C PF14914.6 CBY39784.1 - 0.11 12.5 0.6 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF3671 PF12420.8 CBY39784.1 - 3 8.0 7.4 3.2 7.8 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function zf-AN1 PF01428.16 CBY39787.1 - 8.6e-10 38.6 7.4 8.6e-10 38.6 7.4 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger RT_RNaseH PF17917.1 CBY39790.1 - 2.4e-27 95.3 0.2 1.1e-26 93.1 0.1 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CBY39790.1 - 3.2e-24 84.8 0.0 1.3e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY39790.1 - 2e-20 73.1 0.0 5.4e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY39790.1 - 2e-15 56.9 0.3 4.1e-15 55.9 0.3 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CBY39790.1 - 9.2e-14 51.3 0.0 2.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CBY39790.1 - 1.9e-05 25.1 0.0 7e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CBY39790.1 - 0.0069 16.7 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.6 CBY39790.1 - 0.016 15.0 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 CBY39790.1 - 0.052 14.2 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Endonuc-BglII PF09195.11 CBY39790.1 - 0.11 12.3 0.2 0.26 11.1 0.2 1.6 1 0 0 1 1 1 0 Restriction endonuclease BglII Glutaredoxin2_C PF04399.13 CBY39791.1 - 0.021 14.6 2.5 0.028 14.3 2.5 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF3369 PF11849.8 CBY39791.1 - 0.035 14.3 1.8 0.045 14.0 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3369) HSP70 PF00012.20 CBY39791.1 - 0.2 9.8 17.2 0.24 9.5 17.2 1.0 1 0 0 1 1 1 0 Hsp70 protein SpoIIIAH PF12685.7 CBY39791.1 - 0.22 11.3 13.6 0.27 11.0 13.6 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Patched PF02460.18 CBY39791.1 - 0.6 8.1 4.1 0.87 7.6 4.1 1.2 1 0 0 1 1 1 0 Patched family DUF262 PF03235.14 CBY39791.1 - 0.86 9.7 10.6 1.1 9.4 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 Asp-B-Hydro_N PF05279.11 CBY39791.1 - 1.6 8.8 20.2 1.8 8.5 20.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region O-antigen_lig PF13425.6 CBY39791.1 - 2.3 6.9 10.3 3.5 6.3 10.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AAA_11 PF13086.6 CBY39791.1 - 3.9 7.2 14.1 5.2 6.8 14.1 1.3 1 0 0 1 1 1 0 AAA domain zinc_ribbon_16 PF17034.5 CBY39792.1 - 4.2 7.6 17.6 6.5 7.0 15.3 2.4 2 1 0 2 2 2 0 Zinc-ribbon like family G-alpha PF00503.20 CBY39794.1 - 3.1e-94 316.1 4.5 3.7e-94 315.8 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY39794.1 - 3.5e-12 46.1 0.0 7.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBY39794.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2231 PF09990.9 CBY39794.1 - 0.19 12.2 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) IF-2B PF01008.17 CBY39795.1 - 1.2e-45 155.9 1.3 2.3e-45 155.0 1.3 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family PapD-like PF14874.6 CBY39796.1 - 0.17 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar-associated PapD-like Sporozoite_P67 PF05642.11 CBY39797.1 - 0.22 9.6 9.6 0.32 9.0 9.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GLTP PF08718.11 CBY39798.1 - 1.1e-30 106.9 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) ISPD_C PF18706.1 CBY39798.1 - 0.041 13.5 0.2 0.067 12.8 0.2 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain DUF2833 PF11090.8 CBY39798.1 - 0.14 12.5 0.3 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) Ion_trans_2 PF07885.16 CBY39799.1 - 4.7e-20 71.3 9.7 1.6e-11 44.0 8.5 3.0 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 CBY39799.1 - 0.00087 18.6 8.1 0.047 12.9 2.6 2.6 2 1 0 2 2 2 2 Ion transport protein TAP_C PF03943.13 CBY39799.1 - 0.17 11.5 0.3 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 TAP C-terminal domain CENP-M PF11111.8 CBY39800.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) zf-RING_4 PF14570.6 CBY39801.1 - 2.3e-16 59.3 9.8 4e-16 58.5 9.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CBY39801.1 - 2.2e-05 24.2 8.2 4.1e-05 23.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBY39801.1 - 0.00074 19.3 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 CBY39801.1 - 0.0075 16.4 1.9 0.021 15.0 1.9 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Nup35_RRM_2 PF14605.6 CBY39801.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4_2 PF13923.6 CBY39801.1 - 0.12 12.2 10.8 0.25 11.2 10.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY39801.1 - 0.2 11.6 8.7 0.41 10.6 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY39801.1 - 0.39 10.9 4.6 0.87 9.8 4.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Asparaginase_2 PF01112.18 CBY39801.1 - 7.1 5.6 6.1 1 8.3 0.7 2.0 2 0 0 2 2 2 0 Asparaginase MARVEL PF01284.23 CBY39802.1 - 3.9e-06 27.0 6.6 5.1e-06 26.6 6.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF373 PF04123.13 CBY39802.1 - 0.31 10.4 1.8 0.46 9.9 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF2892 PF11127.8 CBY39802.1 - 8.3 6.5 8.0 1.4 9.0 1.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DMA PF03474.14 CBY39804.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 DMRTA motif PS_Dcarbxylase PF02666.15 CBY39805.1 - 9.6e-31 106.9 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sushi PF00084.20 CBY39806.1 - 3.4e-05 24.4 6.5 1.1 9.8 0.3 3.3 3 0 0 3 3 3 3 Sushi repeat (SCR repeat) EGF_alliinase PF04863.13 CBY39806.1 - 4.6 7.7 7.4 1.5 9.3 0.2 3.0 2 1 1 3 3 3 0 Alliinase EGF-like domain EGF_2 PF07974.13 CBY39807.1 - 0.0013 19.0 11.5 0.0013 19.0 11.5 5.3 4 1 1 5 5 5 2 EGF-like domain TIL PF01826.17 CBY39807.1 - 0.0016 18.7 4.1 0.0016 18.7 4.1 5.6 4 2 1 5 5 5 1 Trypsin Inhibitor like cysteine rich domain EGF PF00008.27 CBY39807.1 - 0.013 15.8 8.4 0.013 15.8 8.4 4.9 6 0 0 6 6 6 0 EGF-like domain HLH PF00010.26 CBY39808.1 - 1.1e-15 57.3 3.0 2.2e-15 56.3 3.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CBY39808.1 - 0.59 10.1 7.2 0.66 9.9 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fz PF01392.22 CBY39809.1 - 7.6e-29 100.6 4.8 7.6e-29 100.6 4.8 1.4 2 0 0 2 2 2 1 Fz domain PH_RBD PF12068.8 CBY39810.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.4 1 1 0 1 1 1 0 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 CBY39811.1 - 8.4e-41 140.0 0.1 1.3e-40 139.3 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UTP15_C PF09384.10 CBY39811.1 - 0.023 14.4 0.1 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 UTP15 C terminal NYD-SP28_assoc PF14775.6 CBY39811.1 - 0.17 12.0 0.9 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain CENP-T_C PF15511.6 CBY39812.1 - 3.3e-08 33.6 0.1 4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CBY39812.1 - 4.7e-05 23.5 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CBY39812.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY39812.1 - 0.00027 21.1 0.1 0.00046 20.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY39812.1 - 0.00033 21.0 0.2 0.00037 20.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBY39812.1 - 0.012 15.7 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBY39812.1 - 0.046 13.7 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 CBY39812.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GTP_EFTU PF00009.27 CBY39813.1 - 1.4e-20 73.7 0.0 2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBY39813.1 - 0.00039 20.7 1.8 0.0049 17.2 1.8 2.3 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBY39813.1 - 0.0041 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBY39813.1 - 0.0061 16.3 0.6 1.2 8.9 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CBY39813.1 - 0.028 14.6 0.3 12 6.2 0.1 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CBY39813.1 - 0.029 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ig_3 PF13927.6 CBY39814.1 - 2.3e-15 57.0 1.3 1.7e-11 44.5 0.0 3.1 2 1 0 2 2 2 2 Immunoglobulin domain Ig_2 PF13895.6 CBY39814.1 - 1.4e-12 47.8 0.2 7.5e-07 29.4 0.0 3.2 2 1 0 2 2 2 2 Immunoglobulin domain I-set PF07679.16 CBY39814.1 - 2e-09 37.4 0.4 2.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin I-set domain ig PF00047.25 CBY39814.1 - 2.6e-09 37.1 0.1 4.7e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Immunoglobulin domain Adeno_E3_CR1 PF02440.15 CBY39814.1 - 4.5e-05 23.2 0.2 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR1 V-set PF07686.17 CBY39814.1 - 0.00017 21.7 0.9 0.032 14.4 0.0 2.7 2 1 0 2 2 2 1 Immunoglobulin V-set domain Podoplanin PF05808.11 CBY39814.1 - 0.0084 16.2 0.8 0.013 15.6 0.1 1.6 2 0 0 2 2 2 1 Podoplanin C2-set_2 PF08205.12 CBY39814.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Ig_6 PF18452.1 CBY39814.1 - 0.092 12.3 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain PMP1_2 PF08114.11 CBY39814.1 - 1.1 9.1 3.7 0.35 10.7 0.7 1.7 2 0 0 2 2 2 0 ATPase proteolipid family EGF_CA PF07645.15 CBY39815.1 - 3.6e-33 113.5 110.6 1.4e-08 34.8 3.1 11.5 9 1 0 10 10 10 8 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39815.1 - 8.1e-12 45.1 87.4 0.00047 20.3 2.1 11.2 8 2 3 11 11 11 6 EGF domain hEGF PF12661.7 CBY39815.1 - 0.00021 21.8 13.7 0.00072 20.1 3.6 12.5 14 3 0 14 14 14 6 Human growth factor-like EGF cEGF PF12662.7 CBY39815.1 - 0.00032 20.6 0.9 0.00032 20.6 0.9 11.1 9 3 0 9 9 9 5 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY39815.1 - 0.0062 16.8 2.8 0.0062 16.8 2.8 9.9 7 3 4 11 11 11 5 Coagulation Factor Xa inhibitory site Zona_pellucida PF00100.23 CBY39816.1 - 2.6e-30 106.1 6.2 3.5e-30 105.6 6.2 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_CA PF07645.15 CBY39816.1 - 1.1e-09 38.3 9.3 1.1e-09 38.3 9.3 3.8 2 1 1 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39816.1 - 4.2e-08 33.3 11.9 4.2e-08 33.3 11.9 3.5 2 1 1 3 3 3 1 EGF domain FXa_inhibition PF14670.6 CBY39816.1 - 1.6e-05 25.0 27.8 0.03 14.6 8.1 3.5 2 1 0 2 2 2 2 Coagulation Factor Xa inhibitory site hEGF PF12661.7 CBY39816.1 - 0.00055 20.5 5.6 0.00055 20.5 5.6 3.7 3 1 0 3 3 3 1 Human growth factor-like EGF EGF PF00008.27 CBY39816.1 - 0.0036 17.6 11.0 0.0036 17.6 11.0 3.2 2 0 0 2 2 2 1 EGF-like domain EGF_CA PF07645.15 CBY39817.1 - 6.7e-135 439.1 277.3 3e-11 43.4 8.6 16.7 16 1 1 17 17 17 16 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39817.1 - 1.4e-118 386.7 271.9 7.3e-11 42.1 10.1 17.2 17 0 0 17 17 17 16 EGF domain cEGF PF12662.7 CBY39817.1 - 2.3e-69 228.8 188.7 2e-07 30.8 3.4 18.8 19 1 0 19 19 19 13 Complement Clr-like EGF-like EGF PF00008.27 CBY39817.1 - 5.3e-47 157.7 230.7 3e-05 24.2 5.1 17.9 17 1 0 17 17 17 14 EGF-like domain EGF_MSP1_1 PF12946.7 CBY39817.1 - 1.8e-20 72.7 203.2 2.2e-05 24.4 6.0 15.8 15 0 0 15 15 15 12 MSP1 EGF domain 1 hEGF PF12661.7 CBY39817.1 - 2.7e-20 72.2 201.2 4.6e-05 23.9 3.6 20.2 22 0 0 22 22 22 12 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY39817.1 - 1.7e-10 41.0 242.4 0.00089 19.5 10.9 17.3 13 3 4 17 17 17 12 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY39817.1 - 1.3e-06 28.6 202.7 0.006 16.9 5.3 16.5 16 0 0 16 16 16 10 Pvs28 EGF domain EGF_2 PF07974.13 CBY39817.1 - 0.023 15.1 12.0 0.023 15.1 12.0 16.5 15 1 1 16 16 16 0 EGF-like domain SMP_LBD PF17047.5 CBY39817.1 - 0.066 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain zf-RING_5 PF14634.6 CBY39818.1 - 4.1e-08 33.1 15.6 4.1e-08 33.1 15.6 3.1 3 1 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY39818.1 - 0.0001 22.5 15.8 0.0001 22.5 15.8 3.1 2 1 0 2 2 1 1 Ring finger domain DUF4201 PF13870.6 CBY39818.1 - 0.0011 18.7 17.7 0.0023 17.7 17.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) APG6_N PF17675.1 CBY39818.1 - 0.0015 19.1 12.7 0.0015 19.1 12.7 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 CBY39818.1 - 0.013 15.5 12.0 0.013 15.5 12.0 3.1 2 2 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY39818.1 - 0.028 14.2 16.5 0.028 14.2 16.5 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 CBY39818.1 - 0.084 13.0 13.4 0.14 12.2 13.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 CBY39818.1 - 0.089 12.3 8.4 0.12 11.9 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fez1 PF06818.15 CBY39818.1 - 0.15 12.5 12.1 0.26 11.7 12.1 1.3 1 0 0 1 1 1 0 Fez1 DUF1635 PF07795.11 CBY39818.1 - 0.2 11.5 7.9 0.36 10.7 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3584 PF12128.8 CBY39818.1 - 0.22 9.0 14.8 0.29 8.6 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 CBY39818.1 - 0.34 8.8 6.3 0.5 8.2 6.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_6 PF14835.6 CBY39818.1 - 1.7 8.6 13.4 0.23 11.4 5.0 2.9 2 2 0 2 2 2 0 zf-RING of BARD1-type protein TMF_TATA_bd PF12325.8 CBY39818.1 - 2.3 8.5 15.0 1.8 8.8 8.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4337 PF14235.6 CBY39818.1 - 2.3 8.3 10.3 0.58 10.3 6.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF1664 PF07889.12 CBY39818.1 - 3.8 7.6 8.2 7.6 6.6 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-TFIIB PF13453.6 CBY39818.1 - 4.6 6.6 8.4 1.4 8.3 0.2 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger YgaB PF14182.6 CBY39818.1 - 5.9 7.4 11.3 0.36 11.2 0.9 2.6 1 1 1 2 2 2 0 YgaB-like protein DUF3450 PF11932.8 CBY39818.1 - 6.6 6.0 9.8 9.7 5.4 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 CBY39818.1 - 6.8 5.8 9.9 11 5.2 9.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein Trypsin PF00089.26 CBY39819.1 - 3.1e-35 122.0 0.1 3.9e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Trypsin Galactosyl_T PF01762.21 CBY39820.1 - 2.1e-20 73.4 0.0 1.1e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase SAUGI PF06106.11 CBY39820.1 - 0.024 15.1 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 S. aureus uracil DNA glycosylase inhibitor Glutaredoxin PF00462.24 CBY39823.1 - 3.8e-17 62.3 0.0 5.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CBY39823.1 - 0.0023 18.4 0.4 0.0084 16.5 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CBY39823.1 - 0.006 17.0 0.0 0.0084 16.5 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 CBY39823.1 - 0.0091 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CBY39823.1 - 0.031 14.3 0.1 0.063 13.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 CBY39823.1 - 0.096 12.5 0.4 1.1 9.0 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain PI-PLC-X PF00388.19 CBY39824.1 - 1.5e-58 196.5 0.1 3.3e-58 195.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBY39824.1 - 1.1e-38 132.1 0.4 3.2e-38 130.6 0.4 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SH2 PF00017.24 CBY39824.1 - 6.3e-27 93.5 0.3 2.7e-14 53.0 0.0 3.5 4 0 0 4 4 4 2 SH2 domain SH3_1 PF00018.28 CBY39824.1 - 8.2e-10 38.1 0.5 2.7e-09 36.5 0.5 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CBY39824.1 - 1.4e-09 37.7 0.0 4.8e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CBY39824.1 - 5.7e-06 25.9 0.0 2e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain PH_14 PF17787.1 CBY39824.1 - 0.00062 19.6 0.3 0.11 12.4 0.0 3.6 3 1 0 3 3 3 1 PH domain Peptidase_M14 PF00246.24 CBY39824.1 - 0.0013 18.6 0.4 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Zinc carboxypeptidase UQ_con PF00179.26 CBY39826.1 - 4.1e-37 127.0 0.0 4.9e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M2 PF01401.18 CBY39827.1 - 7.1e-60 203.2 0.1 8.2e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme Peptidase_M3 PF01432.20 CBY39827.1 - 0.0019 17.6 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 TSP_1 PF00090.19 CBY39828.1 - 1.3e-05 25.3 14.9 1.3e-05 25.3 14.9 7.8 8 2 0 8 8 8 2 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY39829.1 - 4.5e-32 110.0 296.5 4.6e-05 23.6 15.4 18.2 16 3 0 16 16 16 14 Thrombospondin type 1 domain Sep15_SelM PF08806.11 CBY39830.1 - 0.0047 17.1 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain Fur_reg_FbpA PF13076.6 CBY39830.1 - 0.045 13.4 1.2 0.2 11.4 0.6 2.3 2 1 0 2 2 2 0 Fur-regulated basic protein A Thr_dehydrat_C PF00585.18 CBY39830.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase ATP-gua_Ptrans PF00217.19 CBY39831.1 - 2.5e-62 210.1 0.0 3.4e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY39831.1 - 7.9e-24 83.8 0.1 2.5e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain Sulfate_transp PF00916.20 CBY39832.1 - 3.4e-66 223.6 15.5 4.3e-66 223.2 15.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CBY39832.1 - 0.003 17.2 0.1 0.17 11.6 0.1 2.3 1 1 0 1 1 1 1 STAS domain ABC_membrane PF00664.23 CBY39833.1 - 7.8e-33 114.3 0.1 1e-32 113.9 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBY39833.1 - 3.9e-32 111.6 0.0 9.5e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 CBY39833.1 - 0.00014 21.2 0.0 0.00037 19.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 CBY39833.1 - 0.024 14.1 0.0 0.1 12.0 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain APS_kinase PF01583.20 CBY39833.1 - 0.034 14.0 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 CBY39833.1 - 0.039 14.4 0.8 0.7 10.3 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_membrane_2 PF06472.15 CBY39833.1 - 0.049 13.0 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_30 PF13604.6 CBY39833.1 - 0.051 13.3 0.3 0.24 11.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBY39833.1 - 0.064 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 CBY39833.1 - 0.074 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBY39833.1 - 0.075 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBY39833.1 - 0.087 12.4 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CBY39833.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 CBY39833.1 - 0.16 12.2 0.6 2.3 8.5 0.6 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CBY39833.1 - 0.16 12.2 0.4 0.58 10.4 0.1 2.0 2 1 0 2 2 1 0 AAA domain 7tm_1 PF00001.21 CBY39836.1 - 1.8e-09 37.3 4.7 2.2e-09 37.1 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SIX1_SD PF16878.5 CBY39837.1 - 1.8e-41 141.1 0.1 3e-40 137.2 0.0 2.4 3 0 0 3 3 3 1 Transcriptional regulator, SIX1, N-terminal SD domain Homeodomain PF00046.29 CBY39837.1 - 5.4e-13 48.6 0.8 1.2e-12 47.5 0.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY39837.1 - 6.5e-10 38.8 2.0 1.9e-09 37.3 0.7 2.3 2 0 0 2 2 2 1 Homeobox KN domain Phage_mat-A PF03863.13 CBY39837.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Phage maturation protein Kelch_1 PF01344.25 CBY39838.1 - 0.017 14.7 0.1 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 Kelch motif BTB_2 PF02214.22 CBY39839.1 - 4e-13 49.5 0.0 8.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 CBY39839.1 - 1.4e-06 27.8 8.7 0.00012 21.4 1.6 2.2 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 CBY39839.1 - 0.00051 20.0 0.2 0.00051 20.0 0.2 1.7 2 0 0 2 2 2 1 Ion channel Mating_N PF12731.7 CBY39839.1 - 0.15 12.2 1.8 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 GTP_EFTU PF00009.27 CBY39840.1 - 2.9e-06 27.0 0.0 4.5e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY39840.1 - 0.00036 20.9 0.0 0.0009 19.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_C PF00679.24 CBY39841.1 - 9.7e-23 80.0 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBY39841.1 - 8.4e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CBY39841.1 - 0.00024 21.1 0.1 0.00062 19.8 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II VHS PF00790.19 CBY39842.1 - 2.4e-23 82.6 0.0 9.5e-23 80.6 0.0 2.0 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CBY39842.1 - 1.2e-11 44.9 0.4 2.3e-11 44.0 0.4 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CBY39842.1 - 1.5e-10 40.5 4.2 4.2e-10 39.1 4.2 1.8 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CBY39842.1 - 1.5e-07 31.7 4.1 6.8e-07 29.5 0.3 2.5 2 0 0 2 2 2 1 GAT domain Holin_BhlA PF10960.8 CBY39842.1 - 0.088 12.8 0.5 0.25 11.3 0.5 1.7 1 0 0 1 1 1 0 BhlA holin family Cyt_c_ox_IV PF12270.8 CBY39843.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ECSCR PF15820.5 CBY39843.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF1143 PF06608.11 CBY39844.1 - 1.7e-28 99.5 3.4 2.5e-28 99.0 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1143) Borrelia_P83 PF05262.11 CBY39845.1 - 0.11 11.0 7.5 0.14 10.6 7.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Trypan_glycop PF00913.19 CBY39845.1 - 0.18 11.0 4.9 0.24 10.6 4.9 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) MDD_C PF18376.1 CBY39845.1 - 0.21 11.3 0.9 18 5.0 0.7 2.1 2 0 0 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain Peptidase_C37 PF05416.12 CBY39845.1 - 0.63 8.5 4.0 0.78 8.2 4.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CLU_N PF15044.6 CBY39845.1 - 1.4 9.4 3.8 1.5 9.3 1.0 2.0 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term HECT PF00632.25 CBY39846.1 - 1.9e-89 300.2 0.1 2.6e-89 299.8 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY39846.1 - 6.1e-37 125.4 26.0 9.1e-11 41.7 2.5 4.5 4 0 0 4 4 4 4 WW domain C2 PF00168.30 CBY39846.1 - 7.8e-13 48.6 0.0 6.8e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 C2 domain rve PF00665.26 CBY39847.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Toxin_8 PF07365.12 CBY39848.1 - 0.046 13.9 0.3 0.046 13.9 0.3 1.8 2 0 0 2 2 2 0 Alpha conotoxin precursor ChpA-C PF03777.13 CBY39848.1 - 0.1 12.5 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 ChpA-C YycI PF09648.10 CBY39848.1 - 0.15 11.7 4.7 0.065 12.8 2.3 1.5 2 0 0 2 2 2 0 YycH protein CRR7 PF12095.8 CBY39848.1 - 0.2 12.2 1.1 0.37 11.3 0.5 1.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Tmemb_185A PF10269.9 CBY39849.1 - 2.7e-42 145.2 21.4 3.6e-42 144.8 21.4 1.1 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein EMP70 PF02990.16 CBY39849.1 - 0.49 9.0 17.7 0.66 8.6 3.9 2.7 1 1 2 3 3 3 0 Endomembrane protein 70 Amidohydro_3 PF07969.11 CBY39850.1 - 5.7e-62 210.7 0.0 6.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBY39850.1 - 3.3e-06 26.6 0.0 0.0014 18.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Sulfotransfer_2 PF03567.14 CBY39851.1 - 1.1e-33 117.2 0.0 1.9e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family NDK PF00334.19 CBY39852.1 - 5.7e-53 178.5 0.0 6.8e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Connexin PF00029.19 CBY39854.1 - 4e-25 89.0 0.3 4.7e-25 88.7 0.3 1.1 1 0 0 1 1 1 1 Connexin MFS_1 PF07690.16 CBY39855.1 - 3.6e-32 111.7 35.5 3.3e-30 105.2 21.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Apocytochr_F_N PF16639.5 CBY39856.1 - 0.063 13.6 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Apocytochrome F, N-terminal GCP_N_terminal PF17681.1 CBY39857.1 - 1.8e-16 60.7 0.1 3.1e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CBY39857.1 - 5.4e-09 36.0 2.8 0.001 18.6 0.5 3.2 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal STAT_int PF02865.17 CBY39857.1 - 0.064 13.7 0.4 0.4 11.2 0.2 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain Ribosomal_L16 PF00252.18 CBY39858.1 - 4.6e-13 49.3 0.0 6.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Y_phosphatase PF00102.27 CBY39859.1 - 1.4e-32 113.1 0.2 2.4e-32 112.4 0.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TIL PF01826.17 CBY39860.1 - 9.5e-62 205.1 159.4 1.8e-11 44.1 18.3 7.1 7 0 0 7 7 7 7 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 CBY39861.1 - 0.00016 21.8 13.8 0.00016 21.8 13.8 3.1 3 0 0 3 3 3 2 Trypsin Inhibitor like cysteine rich domain PPP1R32 PF15691.5 CBY39864.1 - 0.0076 15.4 0.0 0.0076 15.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 Mub_B2 PF17966.1 CBY39864.1 - 0.047 14.4 0.3 0.064 14.0 0.3 1.3 1 0 0 1 1 1 0 Mub B2-like domain 2OG-FeII_Oxy_3 PF13640.6 CBY39866.1 - 0.15 13.0 0.0 0.4 11.6 0.0 1.6 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Trypsin PF00089.26 CBY39867.1 - 3.3e-44 151.3 1.2 4.4e-44 150.9 1.2 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY39867.1 - 6.1e-05 24.0 0.0 0.00012 23.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY39867.1 - 0.0013 19.1 0.3 0.0024 18.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) BPS1 PF05633.11 CBY39867.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related 2OG-FeII_Oxy_3 PF13640.6 CBY39868.1 - 5.6e-13 49.6 0.0 1.4e-12 48.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily P4Ha_N PF08336.11 CBY39868.1 - 2.5e-08 34.0 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2OG-FeII_Oxy PF03171.20 CBY39868.1 - 0.00018 21.9 0.0 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp5 PF17000.5 CBY39868.1 - 0.18 11.9 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 Myosin_head PF00063.21 CBY39869.1 - 2.5e-275 915.0 3.6 5e-275 914.0 3.6 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CBY39869.1 - 5.9e-40 137.0 89.9 7.5e-40 136.7 89.9 1.1 1 0 0 1 1 1 1 Myosin tail CENP-F_leu_zip PF10473.9 CBY39869.1 - 0.0021 18.1 28.0 0.0021 18.1 28.0 4.4 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 CBY39869.1 - 0.014 15.7 1.0 0.045 14.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Myosin_N PF02736.19 CBY39869.1 - 0.061 13.2 0.6 0.15 11.9 0.6 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_7 PF12775.7 CBY39869.1 - 0.098 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3287 PF11690.8 CBY39869.1 - 1.3 8.7 6.6 1.4 8.6 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) AAA_16 PF13191.6 CBY39869.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain BUD22 PF09073.10 CBY39870.1 - 3.9e-07 29.8 20.9 3.9e-07 29.8 20.9 4.3 2 2 2 4 4 4 1 BUD22 Anillin PF08174.11 CBY39870.1 - 0.049 14.0 1.4 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 Cell division protein anillin MIF4G PF02854.19 CBY39872.1 - 2.8e-33 115.4 5.7 6.5e-19 68.4 0.2 2.6 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.14 CBY39872.1 - 4.7e-12 46.8 8.5 4.7e-12 46.8 8.5 2.3 2 0 0 2 2 2 1 Up-frameshift suppressor 2 PAXX PF15384.6 CBY39872.1 - 0.059 13.1 0.4 0.1 12.3 0.4 1.4 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 THUMP PF02926.17 CBY39873.1 - 0.0058 16.7 0.2 0.027 14.6 0.0 2.0 2 0 0 2 2 2 1 THUMP domain SSP160 PF06933.11 CBY39874.1 - 6.3 4.9 7.0 9 4.4 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FACT-Spt16_Nlob PF14826.6 CBY39875.1 - 2.2e-42 144.6 1.0 4.2e-42 143.7 1.0 1.4 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CBY39875.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 IDO PF01231.18 CBY39875.1 - 0.017 14.0 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase RdRP PF05183.12 CBY39876.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase RdRP PF05183.12 CBY39877.1 - 2.4e-34 119.0 0.0 2.8e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4207 PF13904.6 CBY39878.1 - 6.7e-10 39.1 37.7 6.7e-10 39.1 37.7 4.4 3 2 0 4 4 4 2 Domain of unknown function (DUF4207) Ank_4 PF13637.6 CBY39878.1 - 4.6e-05 23.9 0.0 8.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY39878.1 - 0.0021 18.6 0.0 0.0042 17.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY39878.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) XRN1_D2_D3 PF18334.1 CBY39878.1 - 0.066 13.4 1.2 0.94 9.7 0.0 3.4 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain SPATA3 PF15662.5 CBY39879.1 - 2.3 8.8 6.2 2.8 8.5 6.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Ndc1_Nup PF09531.10 CBY39879.1 - 2.8 6.5 5.3 3 6.4 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COesterase PF00135.28 CBY39880.1 - 2e-78 264.5 0.1 3.5e-78 263.7 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY39880.1 - 8.8e-08 32.3 0.2 0.003 17.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY39880.1 - 0.0046 16.5 0.1 0.0087 15.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tudor_2 PF18104.1 CBY39881.1 - 1e-07 31.5 3.8 0.013 15.1 0.3 3.8 4 0 0 4 4 4 2 Jumonji domain-containing protein 2A Tudor domain DUF4537 PF15057.6 CBY39881.1 - 6.5e-06 26.2 1.2 0.14 12.2 0.0 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4537) TUDOR_5 PF18359.1 CBY39881.1 - 0.00011 21.8 0.3 0.31 10.8 0.0 2.9 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain 1 Tudor-knot PF11717.8 CBY39881.1 - 0.0036 17.2 0.6 0.52 10.2 0.1 3.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.26 CBY39881.1 - 1 9.9 3.3 2.2 8.9 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Alpha-amylase_C PF02806.18 CBY39882.1 - 1e-06 29.1 0.4 2.1e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 CBY39882.1 - 0.00052 19.7 0.4 0.0069 16.0 0.4 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Sulfotransfer_2 PF03567.14 CBY39884.1 - 1.3e-17 64.5 0.1 2.4e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family Astacin PF01400.24 CBY39885.1 - 8.4e-70 234.3 0.1 3.2e-39 134.5 0.0 2.7 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) EGF_CA PF07645.15 CBY39885.1 - 5.2e-07 29.8 17.6 8.7e-05 22.6 7.6 5.6 6 0 0 6 6 6 2 Calcium-binding EGF domain Ldl_recept_a PF00057.18 CBY39885.1 - 1e-05 25.6 19.7 0.0044 17.2 3.5 4.2 2 1 1 3 3 3 2 Low-density lipoprotein receptor domain class A Peptidase_M10 PF00413.24 CBY39885.1 - 0.011 15.6 1.5 9.6 6.0 0.0 3.3 2 1 0 3 3 3 0 Matrixin cEGF PF12662.7 CBY39885.1 - 0.015 15.2 2.1 0.015 15.2 2.1 4.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like TDP43_N PF18694.1 CBY39885.1 - 0.066 13.1 0.0 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DUF3267 PF11667.8 CBY39885.1 - 0.093 13.0 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Putative zincin peptidase Clat_adaptor_s PF01217.20 CBY39889.1 - 6.7e-25 87.7 4.1 7.9e-25 87.5 4.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M24 PF00557.24 CBY39889.1 - 0.054 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 DUF4849 PF16141.5 CBY39889.1 - 0.096 11.9 1.0 0.87 8.8 0.4 2.0 1 1 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 SIR2 PF02146.17 CBY39890.1 - 1.4e-38 132.6 0.1 3.1e-37 128.2 0.1 2.4 1 1 0 1 1 1 1 Sir2 family PNTB PF02233.16 CBY39890.1 - 0.00028 20.0 0.1 0.0059 15.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 CBY39890.1 - 0.00068 19.4 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Zn-ribbon_8 PF09723.10 CBY39890.1 - 0.37 10.9 1.9 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Lectin_C PF00059.21 CBY39892.1 - 1.5e-07 32.1 10.2 5e-07 30.4 10.2 1.9 1 1 0 1 1 1 1 Lectin C-type domain zf-C2H2 PF00096.26 CBY39893.1 - 1.1e-16 60.2 23.0 1.3e-05 25.3 3.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY39893.1 - 1.7e-14 53.5 24.6 4.7e-09 36.3 1.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY39893.1 - 3.7e-10 39.7 20.2 0.0022 18.7 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY39893.1 - 4e-05 23.8 6.4 7.4e-05 23.0 5.8 1.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CBY39893.1 - 0.0045 17.0 15.8 0.21 11.6 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Ogr_Delta PF04606.12 CBY39893.1 - 0.01 15.8 2.3 1.4 8.9 0.1 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 CBY39893.1 - 0.012 16.2 8.6 0.61 10.8 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 CBY39893.1 - 0.047 13.6 10.5 0.13 12.2 0.9 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF4119 PF13494.6 CBY39893.1 - 0.062 13.4 0.0 0.39 10.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-met PF12874.7 CBY39893.1 - 0.2 12.1 5.0 4.2 7.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY39893.1 - 1.1 9.6 9.3 0.17 12.2 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CHORD PF04968.12 CBY39893.1 - 1.5 9.6 8.3 1.9 9.3 2.0 2.4 1 1 1 2 2 2 0 CHORD zf-C2H2_aberr PF17017.5 CBY39893.1 - 2 8.6 3.8 29 4.7 0.9 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Sulfatase_C PF14707.6 CBY39894.1 - 0.11 13.2 0.2 0.21 12.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase TPR_17 PF13431.6 CBY39895.1 - 9.5e-08 31.9 2.3 0.00011 22.3 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY39895.1 - 8.6e-07 28.5 1.5 0.0017 18.0 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 CBY39895.1 - 9.6e-06 25.3 1.7 0.0081 16.2 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39895.1 - 6.4e-05 23.1 4.2 0.0001 22.5 4.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBY39895.1 - 0.00014 21.8 1.7 0.0083 16.3 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY39895.1 - 0.00018 21.9 0.6 0.0013 19.2 0.4 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY39895.1 - 0.00041 20.1 6.5 0.0075 16.0 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY39895.1 - 0.003 17.8 0.9 0.064 13.5 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY39895.1 - 0.0084 16.2 0.0 0.031 14.4 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY39895.1 - 0.058 14.1 0.4 1.2 10.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBY39895.1 - 0.069 13.5 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBY39895.1 - 0.072 13.9 0.0 0.39 11.7 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY39895.1 - 0.12 12.5 0.1 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MBD PF01429.19 CBY39896.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain zf-NPL4 PF05020.15 CBY39896.1 - 0.065 13.4 0.7 0.082 13.1 0.7 1.2 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region PI_PP_I PF18363.1 CBY39896.1 - 0.082 13.1 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain fn3 PF00041.21 CBY39899.1 - 2.6e-10 40.5 0.1 1.2e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY39899.1 - 0.041 14.5 0.3 0.24 12.0 0.1 2.2 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Baculo_PEP_C PF04513.12 CBY39899.1 - 0.055 13.5 6.2 0.11 12.5 6.0 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HBD PF18534.1 CBY39899.1 - 0.2 11.8 2.1 0.25 11.5 0.4 2.0 2 0 0 2 2 2 0 Helical bundle domain DUF2935 PF11155.8 CBY39899.1 - 0.32 11.4 5.2 0.66 10.3 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF3209 PF11483.8 CBY39899.1 - 0.59 10.6 3.7 0.77 10.2 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) TMPIT PF07851.13 CBY39899.1 - 0.79 8.9 7.0 1.4 8.1 7.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein FadA PF09403.10 CBY39899.1 - 3.6 8.1 16.9 6.9 7.2 12.6 3.2 1 1 0 1 1 1 0 Adhesion protein FadA MULE PF10551.9 CBY39901.1 - 0.00095 19.5 0.1 0.0023 18.3 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain ABC_membrane PF00664.23 CBY39902.1 - 1.7e-63 214.9 28.1 6.8e-33 114.5 14.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY39902.1 - 3.2e-21 76.3 0.0 7.2e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY39902.1 - 0.0031 17.5 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBY39902.1 - 0.013 15.2 0.2 0.038 13.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBY39902.1 - 0.03 14.4 0.1 0.085 12.9 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBY39902.1 - 0.034 14.5 0.1 0.085 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 CBY39902.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 CBY39902.1 - 0.15 11.3 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 CBY39902.1 - 0.17 11.3 0.2 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 CBY39902.1 - 4.9 7.2 5.4 0.5 10.4 0.2 2.0 3 0 0 3 3 3 0 Dynamin family MTABC_N PF16185.5 CBY39903.1 - 0.0063 16.0 2.4 0.0082 15.7 2.4 1.2 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region Got1 PF04178.12 CBY39903.1 - 0.0079 16.6 0.6 0.0079 16.6 0.6 2.4 3 1 0 3 3 3 1 Got1/Sft2-like family DUF1129 PF06570.11 CBY39903.1 - 0.072 12.6 3.5 0.31 10.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Maf PF02545.14 CBY39904.1 - 8.1e-40 136.4 0.0 8.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Acyltransferase PF01553.21 CBY39907.1 - 1.3e-15 57.2 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBY39907.1 - 3.5e-12 46.2 0.0 6.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF2232 PF09991.9 CBY39907.1 - 0.015 14.5 3.5 0.015 14.5 3.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) PCI PF01399.27 CBY39908.1 - 7.8e-19 68.1 1.9 1.9e-18 66.9 0.8 2.2 2 0 0 2 2 2 1 PCI domain eIF3_N PF09440.10 CBY39908.1 - 8.3e-18 65.1 2.3 8.3e-18 65.1 2.3 2.5 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain E3_UFM1_ligase PF09743.9 CBY39908.1 - 0.00072 19.3 0.1 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 GerD PF17898.1 CBY39908.1 - 0.0015 18.5 0.5 0.0066 16.4 0.5 2.1 1 0 0 1 1 1 1 Spore germination GerD central core domain CSN8_PSD8_EIF3K PF10075.9 CBY39908.1 - 0.0024 17.9 1.1 0.0067 16.4 0.3 2.1 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family HMW1C_N PF18071.1 CBY39908.1 - 0.0035 17.1 1.8 2.8 7.7 0.1 3.3 3 0 0 3 3 3 2 HMW1C N-terminal DUF771 PF05595.11 CBY39908.1 - 0.0045 16.9 0.3 0.1 12.6 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF771) TPR_2 PF07719.17 CBY39908.1 - 0.041 14.0 1.7 1.1 9.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY39908.1 - 0.062 13.5 0.7 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_9 PF00759.19 CBY39909.1 - 2e-106 356.9 2.8 2.5e-106 356.6 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sod_Fe_N PF00081.22 CBY39910.1 - 1.4e-09 38.3 1.1 1.3e-08 35.2 0.2 2.3 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain APC_r PF05923.12 CBY39911.1 - 0.15 11.9 9.1 2.2 8.1 0.0 3.6 3 0 0 3 3 3 0 APC repeat Glyco_transf_43 PF03360.16 CBY39912.1 - 2.1e-64 217.1 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 CCDC92 PF14916.6 CBY39912.1 - 0.017 14.8 0.8 0.095 12.5 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function HALZ PF02183.18 CBY39912.1 - 0.066 13.4 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase_Tyr PF07714.17 CBY39914.1 - 6.5e-36 123.9 0.5 1.7e-34 119.3 0.5 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY39914.1 - 1e-17 64.4 0.0 1.8e-17 63.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY39914.1 - 0.0087 14.9 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PDZ PF00595.24 CBY39915.1 - 0.00029 21.1 0.1 0.00037 20.8 0.1 1.3 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY39915.1 - 0.00063 19.5 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY39915.1 - 0.043 14.1 0.0 0.051 13.9 0.0 1.1 1 0 0 1 1 1 0 PDZ domain Pkinase_Tyr PF07714.17 CBY39916.1 - 2.1e-05 23.9 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY39916.1 - 0.00055 19.4 0.1 0.04 13.3 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain DUF4342 PF14242.6 CBY39916.1 - 0.081 12.9 0.4 0.21 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Rotavirus_VP7 PF05868.11 CBY39917.1 - 0.0029 17.0 1.3 0.38 10.1 0.2 2.3 2 0 0 2 2 2 2 Rotavirus major outer capsid protein VP7 DUF402 PF04167.13 CBY39917.1 - 0.0094 16.1 0.1 8.8 6.6 0.0 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF402) TAFA PF12020.8 CBY39917.1 - 0.02 15.3 2.5 2 8.9 0.1 3.1 3 0 0 3 3 3 0 TAFA family DUF4596 PF15363.6 CBY39917.1 - 0.2 11.9 2.0 24 5.3 0.2 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) zf-C2HC PF01530.18 CBY39918.1 - 7e-25 86.9 32.3 7.5e-13 48.4 8.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2HC type IBR PF01485.21 CBY39918.1 - 0.026 14.8 4.0 0.75 10.1 0.2 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain BES1_N PF05687.13 CBY39918.1 - 2.3 8.6 7.7 2.1 8.7 4.6 2.1 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal MKLP1_Arf_bdg PF16540.5 CBY39919.1 - 6.6e-30 103.3 0.1 6.6e-30 103.3 0.1 1.9 2 1 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Kinesin PF00225.23 CBY39920.1 - 5.3e-86 288.6 0.2 7.1e-86 288.1 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY39920.1 - 3.6e-18 65.9 0.0 2.7e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding zf-RING_2 PF13639.6 CBY39921.1 - 7.5e-07 29.4 10.6 7.5e-07 29.4 10.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY39921.1 - 3.3e-06 26.9 9.3 7.8e-06 25.7 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY39921.1 - 7e-05 22.7 11.0 7e-05 22.7 11.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY39921.1 - 0.00066 19.7 6.3 0.0013 18.7 5.0 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY39921.1 - 0.0016 18.2 9.6 0.004 16.9 9.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY39921.1 - 0.0022 17.8 11.3 0.0022 17.8 11.3 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY39921.1 - 0.0034 17.4 6.0 0.0034 17.4 6.0 2.8 3 1 1 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY39921.1 - 0.0047 16.8 10.1 0.018 14.9 10.1 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBY39921.1 - 0.011 16.0 7.4 0.05 13.9 7.4 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain CALCOCO1 PF07888.11 CBY39921.1 - 0.015 14.2 30.7 0.02 13.8 30.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C3HC4_2 PF13923.6 CBY39921.1 - 0.025 14.4 9.3 0.074 12.9 9.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NPV_P10 PF05531.12 CBY39921.1 - 0.037 14.5 13.3 0.42 11.1 0.4 3.5 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Tmemb_55A PF09788.9 CBY39921.1 - 0.063 12.4 4.5 0.028 13.5 1.9 1.6 1 1 0 1 1 1 0 Transmembrane protein 55A zf-RING_10 PF16685.5 CBY39921.1 - 0.071 13.3 5.6 0.27 11.4 5.6 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 KxDL PF10241.9 CBY39921.1 - 0.13 12.5 24.8 0.3 11.4 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF3772 PF12607.8 CBY39921.1 - 0.19 11.5 1.0 0.46 10.3 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Golgin_A5 PF09787.9 CBY39921.1 - 0.24 10.8 35.6 0.095 12.2 21.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 zf-UDP PF14569.6 CBY39921.1 - 0.26 11.4 5.5 0.68 10.1 5.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 CBY39921.1 - 0.33 10.6 7.8 0.71 9.5 7.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBY39921.1 - 0.36 11.0 15.5 0.098 12.8 10.5 2.6 3 1 1 4 4 2 0 zinc finger of C3HC4-type, RING ACR_tran PF00873.19 CBY39921.1 - 1.3 6.5 11.1 1.5 6.3 11.1 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family OmpH PF03938.14 CBY39921.1 - 1.5 9.2 38.9 1.5 9.1 19.5 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4175 PF13779.6 CBY39921.1 - 1.9 6.3 17.2 2.5 5.9 17.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ax_dynein_light PF10211.9 CBY39921.1 - 2.3 8.1 42.0 3.7 7.4 0.4 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain TEX13 PF15186.6 CBY39921.1 - 2.9 7.6 22.6 0.073 12.7 8.3 2.8 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family ATG16 PF08614.11 CBY39921.1 - 3 8.0 31.5 4.5 7.5 16.6 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 CBY39921.1 - 3 7.6 39.8 1.4 8.7 0.4 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4045 PF13254.6 CBY39921.1 - 3.6 7.1 15.3 4.3 6.9 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) COG2 PF06148.11 CBY39921.1 - 3.6 7.7 24.0 0.75 9.9 2.5 3.9 1 1 3 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 CBY39921.1 - 7.5 6.2 23.2 0.52 10.0 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CUB PF00431.20 CBY39922.1 - 6.5e-08 32.9 0.4 1.2e-07 32.0 0.4 1.4 1 0 0 1 1 1 1 CUB domain DUF4930 PF16284.5 CBY39922.1 - 0.049 13.6 0.1 0.093 12.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4930) MFS_1 PF07690.16 CBY39923.1 - 1.6e-22 79.9 21.8 6.8e-12 45.0 2.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 CBY39923.1 - 0.014 15.4 4.5 0.049 13.6 0.9 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S MerC PF03203.14 CBY39923.1 - 0.034 14.6 0.1 0.034 14.6 0.1 4.3 2 2 2 4 4 4 0 MerC mercury resistance protein FtsL PF04999.13 CBY39923.1 - 0.4 10.7 2.1 2.2 8.3 0.3 2.5 2 0 0 2 2 2 0 Cell division protein FtsL LRR_8 PF13855.6 CBY39924.1 - 1.2e-31 108.2 20.0 8.4e-12 44.7 0.3 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBY39924.1 - 7.3e-15 54.8 20.4 8.9e-06 26.0 0.1 6.1 3 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBY39924.1 - 8.5e-09 35.4 1.7 0.00016 21.6 1.1 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 CBY39924.1 - 9.3e-06 25.2 3.9 0.0029 17.1 1.2 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 CBY39924.1 - 2.8e-05 24.0 15.3 0.81 10.5 0.0 7.8 8 1 0 8 8 8 2 Leucine Rich Repeat VAR1 PF05316.12 CBY39924.1 - 0.0024 17.0 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein (VAR1) LRR_6 PF13516.6 CBY39924.1 - 0.21 11.7 19.1 4.1 7.7 0.1 6.3 6 1 1 7 7 7 0 Leucine Rich repeat BUD22 PF09073.10 CBY39925.1 - 0.33 10.3 22.2 0.38 10.1 22.2 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CBY39925.1 - 0.8 7.8 18.9 0.89 7.7 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CBY39925.1 - 2.3 6.4 15.6 2.5 6.3 15.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CBY39925.1 - 7.2 5.9 22.2 8.7 5.7 22.2 1.1 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 CBY39925.1 - 7.5 4.5 11.1 8.7 4.3 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CRAL_TRIO PF00650.20 CBY39926.1 - 3.2e-17 62.7 0.1 5.1e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBY39926.1 - 0.064 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain UL41A PF17591.2 CBY39927.1 - 1.5 8.9 4.3 1.2 9.3 2.4 1.8 1 1 1 2 2 2 0 Herpesvirus UL41A Trefoil PF00088.18 CBY39928.1 - 1.5e-05 24.8 5.1 5.4e-05 23.0 5.1 2.0 1 0 0 1 1 1 1 Trefoil (P-type) domain NAM-associated PF14303.6 CBY39929.1 - 0.023 15.4 2.3 0.075 13.8 2.3 1.9 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4698 PF15769.5 CBY39929.1 - 4.7 6.1 12.1 5.8 5.8 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Hamartin PF04388.12 CBY39929.1 - 6.6 5.3 18.9 7.9 5.0 18.9 1.0 1 0 0 1 1 1 0 Hamartin protein SWI-SNF_Ssr4 PF08549.10 CBY39929.1 - 7.3 5.1 13.4 8.5 4.9 13.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FXa_inhibition PF14670.6 CBY39931.1 - 3.4e-12 46.4 8.7 3.4e-12 46.4 8.7 3.8 4 0 0 4 4 4 1 Coagulation Factor Xa inhibitory site Sushi PF00084.20 CBY39931.1 - 2.7e-07 31.1 16.5 0.00087 19.8 0.4 3.9 4 0 0 4 4 4 2 Sushi repeat (SCR repeat) EGF PF00008.27 CBY39931.1 - 0.0028 17.9 17.7 0.0073 16.6 7.4 4.2 3 0 0 3 3 3 2 EGF-like domain cEGF PF12662.7 CBY39931.1 - 0.0033 17.3 13.0 0.014 15.3 2.8 3.2 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY39931.1 - 0.017 15.3 7.2 0.017 15.3 7.2 4.3 4 1 1 5 5 5 0 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39931.1 - 0.12 12.6 13.3 0.49 10.6 3.2 4.2 3 0 0 3 3 3 0 EGF domain hEGF PF12661.7 CBY39931.1 - 2.4 8.9 15.8 0.43 11.3 5.5 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY39932.1 - 1.2e-08 34.9 7.0 1.2e-08 34.9 7.0 2.0 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY39932.1 - 0.0021 18.2 3.9 0.0021 18.2 3.9 1.8 2 1 0 2 2 2 1 EGF domain EB PF01683.18 CBY39932.1 - 0.0035 17.6 6.6 0.0069 16.6 6.6 1.5 1 1 0 1 1 1 1 EB module FXa_inhibition PF14670.6 CBY39932.1 - 0.013 15.8 7.7 0.013 15.8 7.7 2.0 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY39932.1 - 0.023 15.0 10.9 0.042 14.2 7.9 2.6 1 1 2 3 3 3 0 EGF-like domain cEGF PF12662.7 CBY39932.1 - 0.062 13.2 0.4 0.062 13.2 0.4 3.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY39932.1 - 0.086 13.5 4.2 0.086 13.5 4.2 2.5 2 1 1 3 3 3 0 Human growth factor-like EGF PLAT PF01477.23 CBY39935.1 - 7.5e-44 149.0 1.6 7.1e-23 81.4 0.1 3.1 3 0 0 3 3 3 3 PLAT/LH2 domain Lactamase_B PF00753.27 CBY39936.1 - 1.1e-15 58.2 2.9 9.4e-14 51.9 2.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY39936.1 - 0.0036 16.8 0.9 0.006 16.1 0.9 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUB PF00431.20 CBY39937.1 - 1.9e-08 34.6 0.0 3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 CUB domain Spt20 PF12090.8 CBY39937.1 - 2.8 7.5 12.2 3.8 7.1 12.2 1.1 1 0 0 1 1 1 0 Spt20 family ADH_N PF08240.12 CBY39938.1 - 5.3e-29 100.3 4.9 7.6e-29 99.8 4.9 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CBY39938.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus S8_pro-domain PF16470.5 CBY39939.1 - 0.096 13.5 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase S8 pro-domain UNC80 PF15778.5 CBY39940.1 - 3.2e-20 72.5 0.4 1.6e-17 63.7 0.4 2.7 1 1 0 1 1 1 1 Cation channel complex component UNC80 DUF719 PF05334.13 CBY39940.1 - 0.18 12.0 5.5 0.069 13.3 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) adh_short PF00106.25 CBY39941.1 - 3.2e-22 79.0 0.0 5.1e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY39941.1 - 7.4e-19 68.2 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EF-hand_5 PF13202.6 CBY39941.1 - 0.033 13.7 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 EF hand KR PF08659.10 CBY39941.1 - 0.11 12.4 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 KR domain EF-hand_7 PF13499.6 CBY39941.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Actin PF00022.19 CBY39942.1 - 4.3e-152 506.5 0.0 1.4e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin HMG_box PF00505.19 CBY39944.1 - 1.1e-17 64.1 2.7 1.6e-17 63.6 2.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY39944.1 - 4.4e-07 30.4 2.2 5.6e-07 30.1 0.9 1.8 2 0 0 2 2 2 1 HMG-box domain Ribosomal_L21e PF01157.18 CBY39945.1 - 8.4e-45 150.8 6.1 8.4e-45 150.8 6.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e CRCB PF02537.15 CBY39947.1 - 3e-31 107.6 16.8 8.1e-17 61.3 2.2 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Gpi1 PF05024.15 CBY39947.1 - 0.03 14.4 5.5 0.031 14.4 3.4 2.1 1 1 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) SUR7 PF06687.12 CBY39947.1 - 0.16 11.6 7.6 0.29 10.7 0.6 2.8 2 1 1 3 3 3 0 SUR7/PalI family Ndc1_Nup PF09531.10 CBY39948.1 - 2.1e-29 102.7 27.0 1.5e-28 99.9 27.0 1.9 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Isochorismatase PF00857.20 CBY39949.1 - 6.2e-31 107.9 0.0 7.3e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF3439 PF11921.8 CBY39950.1 - 0.15 12.0 0.8 0.26 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NUDIX PF00293.28 CBY39953.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain MCR_beta_N PF02783.15 CBY39953.1 - 0.02 14.5 0.2 0.031 13.9 0.2 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Heme_oxygenase PF01126.20 CBY39954.1 - 8.8e-11 42.0 0.1 2.1e-10 40.7 0.1 1.6 1 1 0 1 1 1 1 Heme oxygenase NGP1NT PF08153.12 CBY39955.1 - 7.9e-48 161.9 0.4 1.6e-47 160.9 0.4 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBY39955.1 - 9.1e-16 58.0 0.0 6e-13 48.9 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY39955.1 - 9.9e-07 28.4 0.0 7.8e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBY39955.1 - 0.0013 18.6 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CBY39955.1 - 0.0071 15.8 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CBY39955.1 - 3.8 7.5 13.7 3.3 7.7 0.1 4.6 3 2 1 4 4 4 0 Dynamin family MOZ_SAS PF01853.18 CBY39956.1 - 5.9e-80 267.1 0.1 9.9e-80 266.4 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY39956.1 - 5.1e-21 74.0 3.6 1.4e-20 72.7 3.6 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Linker_histone PF00538.19 CBY39956.1 - 4.1e-07 30.3 0.1 1.4e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family Acetyltransf_7 PF13508.7 CBY39956.1 - 0.0047 17.3 0.0 0.0097 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.29 CBY39956.1 - 0.056 13.4 29.0 0.053 13.4 13.5 3.5 2 1 1 3 3 3 0 PHD-finger HTH_IclR PF09339.10 CBY39956.1 - 0.11 12.4 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain C1_1 PF00130.22 CBY39956.1 - 0.38 10.7 22.4 2.8 7.9 1.5 4.3 2 1 2 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ PF00226.31 CBY39957.1 - 3.4e-13 49.5 0.4 7.7e-13 48.4 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Cytochrome_C7 PF14522.6 CBY39957.1 - 0.15 12.1 2.6 0.37 10.8 2.6 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c RINT1_TIP1 PF04437.13 CBY39958.1 - 1.2e-05 24.4 5.1 4.2e-05 22.6 5.1 1.7 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Pesticin PF16754.5 CBY39958.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term MLD PF11647.8 CBY39958.1 - 2.4 8.5 5.7 6 7.2 1.3 2.5 1 1 1 2 2 2 0 Membrane Localization Domain PRP38 PF03371.15 CBY39959.1 - 1.8e-58 197.3 0.7 2.9e-58 196.6 0.7 1.3 1 0 0 1 1 1 1 PRP38 family GAGA_bind PF06217.12 CBY39959.1 - 0.0078 16.5 4.2 0.01 16.2 4.2 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family FUN14 PF04930.15 CBY39959.1 - 0.15 12.5 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 FUN14 family PRP38_assoc PF12871.7 CBY39959.1 - 0.74 10.5 42.8 3.4 8.3 42.8 1.9 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4407 PF14362.6 CBY39959.1 - 0.81 9.0 5.5 1 8.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_U57 PF05582.12 CBY39959.1 - 1.1 8.5 3.7 1.8 7.7 3.7 1.5 1 0 0 1 1 1 0 YabG peptidase U57 Toxin_36 PF10550.9 CBY39959.1 - 5.8 8.5 9.5 1.8 10.1 5.5 2.4 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin Nucleo_P87 PF07267.11 CBY39959.1 - 6.6 5.5 9.9 8.8 5.0 9.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RabGAP-TBC PF00566.18 CBY39960.1 - 2.6e-42 144.9 5.3 2.6e-42 144.9 5.3 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Usg PF06233.12 CBY39960.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Usg-like family ASXH PF13919.6 CBY39960.1 - 0.031 14.3 2.3 2.4 8.2 0.0 3.3 3 0 0 3 3 3 0 Asx homology domain CNH PF00780.22 CBY39961.1 - 2.8e-12 46.8 0.0 4.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain HIP1_clath_bdg PF16515.5 CBY39961.1 - 0.0075 16.9 10.6 0.0075 16.9 10.6 6.7 2 2 4 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 CBY39961.1 - 0.011 15.1 84.5 0.017 14.5 17.4 4.6 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 CBY39961.1 - 0.011 15.4 81.4 0.12 12.1 3.5 5.4 1 1 3 5 5 5 0 Domain of unknown function (DUF4201) Filament PF00038.21 CBY39961.1 - 0.26 10.8 90.4 0.013 15.1 45.5 2.8 1 1 1 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 CBY39961.1 - 0.4 11.1 87.5 0.45 10.9 15.4 4.3 1 1 2 4 4 4 0 Fez1 Spc7 PF08317.11 CBY39961.1 - 0.57 9.0 92.4 0.16 10.8 24.2 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein Rab5-bind PF09311.11 CBY39961.1 - 1.9 7.8 86.9 0.28 10.5 9.3 3.8 1 1 3 4 4 4 0 Rabaptin-like protein ATG16 PF08614.11 CBY39961.1 - 2.6 8.2 93.3 42 4.3 26.9 5.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 CBY39961.1 - 4.2 6.7 95.3 4 6.8 26.1 4.2 1 1 3 4 4 4 0 Golgin subfamily A member 5 ADIP PF11559.8 CBY39961.1 - 6 6.9 89.7 0.12 12.5 17.0 6.0 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 CBY39961.1 - 8.6 6.4 98.9 0.9 9.6 10.7 5.9 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BTD PF09270.10 CBY39965.1 - 3.5e-16 59.8 0.1 7.2e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain MIP PF00230.20 CBY39966.1 - 1.6e-13 50.9 1.1 2e-13 50.6 1.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein AAA_30 PF13604.6 CBY39968.1 - 0.029 14.1 0.1 0.15 11.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain Ion_trans PF00520.31 CBY39969.1 - 4.6e-42 143.9 8.1 7.3e-42 143.3 8.1 1.3 1 0 0 1 1 1 1 Ion transport protein GPHH PF16905.5 CBY39969.1 - 7.8e-31 105.6 0.1 1.5e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ca_chan_IQ PF08763.11 CBY39969.1 - 1.1e-27 96.0 0.1 2.2e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain PKD_channel PF08016.12 CBY39969.1 - 6.3e-08 31.7 8.6 1.1e-07 30.9 8.6 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ras PF00071.22 CBY39970.1 - 6.4e-53 178.7 0.0 7.3e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY39970.1 - 3.8e-19 69.1 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY39970.1 - 7.1e-07 28.8 0.0 9.6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY39970.1 - 0.015 14.8 0.1 0.089 12.3 0.1 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Chromo_shadow PF01393.19 CBY39971.1 - 4.4e-24 84.3 0.5 1.6e-23 82.6 0.1 2.1 3 0 0 3 3 3 1 Chromo shadow domain Chromo PF00385.24 CBY39971.1 - 8.8e-16 57.6 6.7 3.6e-13 49.2 0.7 2.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1918 PF08940.11 CBY39971.1 - 0.13 11.9 0.0 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) CDC24_OB3 PF17244.2 CBY39972.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 EF-hand_5 PF13202.6 CBY39973.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CBY39973.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CBY39974.1 - 1.5e-11 44.6 2.2 1.9e-11 44.2 2.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY39974.1 - 4e-11 41.9 1.9 0.00015 21.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY39974.1 - 8.1e-10 37.5 1.9 0.0001 21.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_11 PF08976.11 CBY39974.1 - 9e-07 29.7 0.0 1e-06 29.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CBY39974.1 - 1.8e-06 27.7 2.7 4.2e-06 26.5 0.4 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY39974.1 - 0.00024 20.5 3.6 0.017 14.6 0.2 2.4 2 0 0 2 2 2 2 EF hand Dockerin_1 PF00404.18 CBY39974.1 - 0.0042 17.2 0.0 0.0072 16.5 0.0 1.6 1 1 0 1 1 1 1 Dockerin type I domain DUF3134 PF11332.8 CBY39974.1 - 0.098 13.0 0.7 0.64 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) Yuri_gagarin PF15934.5 CBY39975.1 - 0.0038 17.1 0.2 0.004 17.0 0.2 1.1 1 0 0 1 1 1 1 Yuri gagarin B PF02216.16 CBY39975.1 - 0.029 14.4 0.6 0.049 13.6 0.6 1.4 1 0 0 1 1 1 0 B domain DUF1640 PF07798.11 CBY39975.1 - 0.046 13.8 3.6 0.061 13.4 3.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4404 PF14357.6 CBY39975.1 - 0.062 13.9 0.4 9.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Occludin_ELL PF07303.13 CBY39975.1 - 0.082 13.6 4.4 0.14 12.9 4.4 1.3 1 0 0 1 1 1 0 Occludin homology domain DUF573 PF04504.14 CBY39975.1 - 0.1 13.2 3.2 0.16 12.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF573 zf-CCHC_4 PF14392.6 CBY39975.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_125 PF06824.11 CBY39976.1 - 0.045 12.6 0.1 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 Metal-independent alpha-mannosidase (GH125) PLAT PF01477.23 CBY39977.1 - 4.5e-19 69.1 0.4 5.5e-19 68.9 0.4 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain Na_K-ATPase PF00287.18 CBY39978.1 - 3.8e-54 183.8 0.0 1.2e-28 100.2 0.0 2.1 1 1 1 2 2 2 2 Sodium / potassium ATPase beta chain Integrin_b_cyt PF08725.11 CBY39980.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Integrin beta cytoplasmic domain CbiQ PF02361.16 CBY39980.1 - 0.035 13.7 0.3 0.043 13.4 0.3 1.1 1 0 0 1 1 1 0 Cobalt transport protein IRK PF01007.20 CBY39981.1 - 6.4e-34 116.8 7.0 8.3e-34 116.4 7.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain IRK_C PF17655.1 CBY39981.1 - 2.4e-28 98.9 0.0 3.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain Ion_trans_2 PF07885.16 CBY39981.1 - 0.22 11.5 16.3 2 8.4 16.3 2.1 1 1 0 1 1 1 0 Ion channel Virul_fac_BrkB PF03631.15 CBY39981.1 - 2 8.0 9.9 3 7.4 3.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB CUB PF00431.20 CBY39982.1 - 5.2e-11 42.9 0.0 9.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 CUB domain ATG_C PF09333.11 CBY39984.1 - 3.3e-20 72.2 0.1 6.9e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CBY39984.1 - 3.5e-08 33.4 0.0 1.2e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG2_CAD PF13329.6 CBY39984.1 - 0.015 15.1 0.2 0.065 12.9 0.2 2.2 1 1 0 1 1 1 0 Autophagy-related protein 2 CAD motif Acyl_transf_3 PF01757.22 CBY39986.1 - 5.2e-08 32.3 36.2 5.2e-08 32.3 36.2 1.4 1 1 0 1 1 1 1 Acyltransferase family Acetyltransf_1 PF00583.25 CBY39988.1 - 3.2e-15 56.4 0.0 4.9e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY39988.1 - 4.7e-10 39.8 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY39988.1 - 1.9e-07 31.0 0.1 3.5e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY39988.1 - 0.00039 20.6 0.1 0.00069 19.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBY39988.1 - 0.0013 18.2 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CBY39988.1 - 0.0015 18.6 0.0 0.0092 16.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY39988.1 - 0.0044 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBY39988.1 - 0.016 15.8 0.0 0.034 14.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY39988.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CBY39988.1 - 0.046 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase 7tm_1 PF00001.21 CBY39989.1 - 7e-20 71.4 9.9 8.7e-19 67.9 9.9 2.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srx PF10328.9 CBY39989.1 - 5.4e-09 36.1 9.6 1.9e-08 34.2 9.5 2.0 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srx DUF2070 PF09843.9 CBY39989.1 - 9.2 4.4 15.5 0.2 9.9 3.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Hema_esterase PF03996.15 CBY39990.1 - 0.086 12.6 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin esterase Gla PF00594.20 CBY39991.1 - 1e-07 32.0 7.7 1e-07 32.0 7.7 2.1 2 1 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TSP_1 PF00090.19 CBY39991.1 - 0.0095 16.1 8.1 0.038 14.2 8.1 2.2 1 1 0 1 1 1 1 Thrombospondin type 1 domain DUF1822 PF08852.11 CBY39992.1 - 0.19 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Trypsin PF00089.26 CBY39993.1 - 1.5e-61 208.0 0.1 3e-61 207.0 0.0 1.5 2 0 0 2 2 2 1 Trypsin CUB PF00431.20 CBY39993.1 - 3e-28 98.3 0.5 9.1e-14 51.7 0.1 2.5 2 0 0 2 2 2 2 CUB domain DUF1986 PF09342.11 CBY39993.1 - 0.076 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sulfatase PF00884.23 CBY39994.1 - 4.8e-26 91.9 0.0 4.1e-25 88.8 0.0 2.0 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.17 CBY39994.1 - 0.0003 19.5 0.0 0.00046 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CBY39994.1 - 0.00038 20.1 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 CBY39994.1 - 0.011 16.0 0.3 0.011 16.0 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Rep_fac_C PF08542.11 CBY39995.1 - 2.2e-15 56.8 0.6 1.3e-14 54.3 0.2 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBY39995.1 - 1.6e-08 34.5 0.1 1.6e-08 34.5 0.1 2.2 3 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CBY39995.1 - 1.3e-05 25.5 0.1 4e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CBY39995.1 - 3.2e-05 24.4 0.8 7.2e-05 23.2 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CBY39995.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Lebercilin PF15619.6 CBY39996.1 - 1.6e-42 145.4 44.2 2.6e-42 144.7 44.2 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Macoilin PF09726.9 CBY39996.1 - 0.014 14.0 31.2 0.025 13.1 31.2 1.4 1 0 0 1 1 1 0 Macoilin family Aminotran_1_2 PF00155.21 CBY39996.1 - 0.22 10.7 2.9 0.093 11.9 0.4 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II GAS PF13851.6 CBY39996.1 - 0.24 10.8 37.0 0.05 12.9 31.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5125 PF17163.4 CBY39997.1 - 0.0075 16.5 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5125) zf-C2H2_jaz PF12171.8 CBY39998.1 - 0.025 14.8 0.5 0.069 13.5 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY39998.1 - 0.047 14.1 2.2 0.053 13.9 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2079 PF09852.9 CBY40000.1 - 9.4e-05 21.4 1.0 0.00011 21.2 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) DUF3144 PF11342.8 CBY40000.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) Profilin PF00235.19 CBY40001.1 - 2.1e-24 86.2 0.2 2.3e-24 86.1 0.2 1.0 1 0 0 1 1 1 1 Profilin Peptidase_M14 PF00246.24 CBY40003.1 - 3.1e-48 165.1 0.0 4.8e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY40003.1 - 0.025 15.0 0.3 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Peptidase_M14 PF00246.24 CBY40004.1 - 6.1e-07 29.5 0.0 6.3e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase G8 PF10162.9 CBY40006.1 - 1.3e-09 38.2 0.0 3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 CBY40006.1 - 0.07 13.0 22.3 0.098 12.5 11.8 4.3 2 1 1 3 3 3 0 Right handed beta helix region ABC_tran PF00005.27 CBY40008.1 - 8.3e-28 97.6 0.0 1.5e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CBY40008.1 - 1.2e-11 44.8 2.7 1.6e-11 44.4 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBY40008.1 - 9.6e-10 38.3 0.1 2.6e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CBY40008.1 - 0.002 18.3 0.2 0.0083 16.2 0.2 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 CBY40008.1 - 0.0021 18.3 0.2 0.022 15.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CBY40008.1 - 0.0031 17.3 0.8 0.012 15.3 0.8 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 CBY40008.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 CBY40008.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein CCB1 PF12046.8 CBY40008.1 - 0.055 12.8 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B T2SSE PF00437.20 CBY40008.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CBY40008.1 - 0.082 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CBY40008.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase PRK PF00485.18 CBY40008.1 - 0.15 11.8 0.1 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Tetraspanin PF00335.20 CBY40009.1 - 0.0055 16.5 1.1 0.0065 16.2 1.1 1.1 1 0 0 1 1 1 1 Tetraspanin family Phage_Treg PF04761.12 CBY40009.1 - 0.11 12.7 0.1 3 8.0 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator DUF4898 PF16239.5 CBY40009.1 - 0.18 11.8 0.8 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) Sulfatase PF00884.23 CBY40010.1 - 2.8e-22 79.5 0.0 3.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CBY40010.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 CBY40010.1 - 0.00036 19.3 0.0 0.00062 18.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CBY40010.1 - 0.00037 20.2 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 CBY40010.1 - 0.0067 17.2 0.0 1 10.1 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 CBY40010.1 - 0.022 14.7 0.0 0.19 11.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF1501 PF07394.12 CBY40010.1 - 0.029 13.5 0.1 0.052 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) RVT_1 PF00078.27 CBY40011.1 - 8.4e-30 103.9 0.0 2.2e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CBY40011.1 - 0.0013 19.4 2.2 0.0019 18.9 0.7 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Replic_Relax PF13814.6 CBY40011.1 - 0.028 14.5 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Replication-relaxation I-set PF07679.16 CBY40012.1 - 6e-46 154.5 0.3 9.3e-13 48.1 0.0 6.6 6 0 0 6 6 6 6 Immunoglobulin I-set domain fn3 PF00041.21 CBY40012.1 - 2.9e-32 110.9 0.0 8.8e-13 48.4 0.0 3.8 3 0 0 3 3 3 3 Fibronectin type III domain Ig_3 PF13927.6 CBY40012.1 - 1e-26 93.3 0.1 4.5e-11 43.2 0.0 6.3 6 0 0 6 6 6 3 Immunoglobulin domain Ig_2 PF13895.6 CBY40012.1 - 3.4e-12 46.5 0.2 9.7e-06 25.8 0.1 5.1 6 0 0 6 6 6 2 Immunoglobulin domain V-set PF07686.17 CBY40012.1 - 7.7e-11 42.1 2.7 0.14 12.3 0.1 5.8 5 1 1 6 6 6 3 Immunoglobulin V-set domain ig PF00047.25 CBY40012.1 - 2.5e-08 34.0 0.2 0.00029 21.0 0.0 4.2 5 0 0 5 5 5 2 Immunoglobulin domain Izumo-Ig PF16706.5 CBY40012.1 - 0.0023 17.9 4.6 3.5 7.8 0.0 4.9 6 0 0 6 6 5 1 Izumo-like Immunoglobulin domain EF-hand_1 PF00036.32 CBY40012.1 - 0.013 15.0 0.3 0.04 13.5 0.3 1.9 1 0 0 1 1 1 0 EF hand C2-set_2 PF08205.12 CBY40012.1 - 0.022 14.8 0.3 0.47 10.6 0.0 2.8 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain EF-hand_5 PF13202.6 CBY40012.1 - 0.023 14.2 0.5 0.069 12.7 0.5 1.8 1 0 0 1 1 1 0 EF hand Receptor_2B4 PF11465.8 CBY40012.1 - 0.048 13.9 0.0 12 6.1 0.0 3.0 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EF-hand_8 PF13833.6 CBY40012.1 - 0.09 12.6 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Ribophorin_II PF05817.14 CBY40012.1 - 0.31 9.5 0.4 1.4 7.4 0.1 1.9 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II Astacin PF01400.24 CBY40015.1 - 1.2e-43 149.0 0.1 3e-43 147.6 0.0 1.6 2 1 0 2 2 2 1 Astacin (Peptidase family M12A) UPF0054 PF02130.17 CBY40015.1 - 0.056 13.2 0.7 0.11 12.3 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 DUF4304 PF14137.6 CBY40015.1 - 0.14 12.3 1.6 0.24 11.6 1.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) EGF PF00008.27 CBY40017.1 - 4.7e-69 228.2 253.9 1e-06 28.9 11.1 16.6 16 0 0 16 16 16 16 EGF-like domain hEGF PF12661.7 CBY40017.1 - 4.8e-34 115.8 205.0 0.0016 19.0 1.3 18.8 17 1 0 17 17 17 15 Human growth factor-like EGF EGF_2 PF07974.13 CBY40017.1 - 1.3e-27 95.8 281.8 0.00087 19.6 7.5 16.3 16 0 0 16 16 16 14 EGF-like domain EGF_3 PF12947.7 CBY40017.1 - 1.2e-16 60.6 239.2 0.0036 17.5 10.1 16.5 14 2 2 16 16 16 14 EGF domain EGF_CA PF07645.15 CBY40017.1 - 0.0029 17.8 36.9 0.0084 16.3 13.2 16.5 2 2 14 16 16 16 5 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY40017.1 - 0.013 15.8 21.5 0.018 15.3 5.7 16.9 8 4 7 15 15 15 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CBY40017.1 - 0.016 15.2 5.8 0.016 15.2 5.8 13.8 14 3 1 15 15 15 0 MSP1 EGF domain 1 O-FucT PF10250.9 CBY40018.1 - 1.1e-08 35.2 4.6 1.2e-08 35.1 3.0 1.8 1 1 1 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF2560 PF10834.8 CBY40018.1 - 0.095 12.9 0.1 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Adap_comp_sub PF00928.21 CBY40019.1 - 9.9e-23 80.8 0.0 1.2e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Folate_rec PF03024.14 CBY40022.1 - 2e-07 31.1 20.4 9e-07 28.9 19.6 2.3 1 1 0 1 1 1 1 Folate receptor family Podoplanin PF05808.11 CBY40022.1 - 0.00023 21.3 2.9 0.00052 20.1 2.9 1.5 1 0 0 1 1 1 1 Podoplanin NES_C_h PF18208.1 CBY40023.1 - 0.11 12.8 10.7 1.4 9.2 8.9 2.3 1 1 1 2 2 2 0 Nicking enzyme C-terminal middle helical domain DUF3450 PF11932.8 CBY40023.1 - 0.7 9.1 9.8 1.5 8.0 9.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 CBY40023.1 - 4.7 6.7 9.1 5.9 6.4 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 CBY40023.1 - 7.8 5.3 4.8 8.5 5.1 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PIG-P PF08510.12 CBY40025.1 - 5.7e-21 74.7 5.6 6.5e-21 74.5 5.6 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CBY40025.1 - 0.0013 19.0 8.7 0.0017 18.6 8.7 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pox_A21 PF05323.12 CBY40025.1 - 0.17 12.5 1.6 0.29 11.7 1.6 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Viral_Beta_CD PF04530.12 CBY40025.1 - 0.64 10.3 2.5 0.43 10.9 1.3 1.4 1 1 0 1 1 1 0 Viral Beta C/D like family MIP PF00230.20 CBY40028.1 - 2.5e-33 115.7 11.7 3.8e-33 115.1 11.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Prominin PF05478.11 CBY40029.1 - 5.1e-10 38.0 5.6 8.3e-10 37.3 5.6 1.3 1 0 0 1 1 1 1 Prominin DUF1642 PF07852.11 CBY40029.1 - 0.0015 19.1 0.7 0.0066 17.0 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1642) DUF3807 PF12720.7 CBY40029.1 - 0.1 12.9 3.8 0.16 12.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) MAGE_N PF12440.8 CBY40029.1 - 4 8.2 9.8 7.3 7.3 9.8 1.5 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal DM PF00751.18 CBY40030.1 - 3.8e-24 84.3 10.9 5.9e-24 83.7 10.9 1.3 1 0 0 1 1 1 1 DM DNA binding domain Peptidase_C93 PF06035.11 CBY40030.1 - 0.076 12.8 0.2 0.094 12.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Tropomyosin_1 PF12718.7 CBY40032.1 - 0.0064 16.7 13.7 0.0064 16.7 13.7 2.3 2 1 1 3 3 3 1 Tropomyosin like RTBV_P46 PF06216.11 CBY40032.1 - 0.02 13.8 1.0 0.03 13.2 1.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FlaC_arch PF05377.11 CBY40032.1 - 0.067 13.6 0.3 0.067 13.6 0.3 3.1 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 CBY40032.1 - 0.17 11.8 6.9 3.8 7.5 0.5 3.5 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Phlebovirus_NSM PF07246.11 CBY40032.1 - 0.64 9.3 10.6 1.2 8.4 10.6 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ZapB PF06005.12 CBY40032.1 - 1.9 9.0 17.7 0.13 12.7 3.1 3.6 3 1 1 4 4 4 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 CBY40032.1 - 3.6 7.7 24.3 0.19 11.8 13.9 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 CBY40032.1 - 6 6.6 24.6 92 2.7 24.8 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 CBY40032.1 - 6.6 6.8 19.7 0.6 10.1 4.7 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 CBY40032.1 - 6.9 7.2 13.2 5.2 7.6 1.1 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_GPO PF05929.11 CBY40032.1 - 9.8 5.7 14.6 3.1 7.3 11.1 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CX9C PF16860.5 CBY40033.1 - 0.00011 22.1 1.3 0.35 10.9 0.7 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1638 PF07796.11 CBY40033.1 - 0.0014 18.7 0.1 0.0014 18.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) CHCH PF06747.13 CBY40033.1 - 0.017 15.3 2.3 0.022 14.9 2.3 1.3 1 0 0 1 1 1 0 CHCH domain UPF0203 PF05254.12 CBY40033.1 - 0.093 13.0 2.4 0.26 11.6 2.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Exo70 PF03081.15 CBY40034.1 - 2.1e-54 185.0 8.6 4.8e-54 183.8 8.6 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit GIT1_C PF12205.8 CBY40034.1 - 0.026 14.6 2.2 11 6.2 0.1 3.7 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term DASH_Dam1 PF08653.10 CBY40034.1 - 0.1 12.4 1.7 8.5 6.3 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.12 CBY40034.1 - 0.18 11.8 12.5 8.5 6.4 1.3 4.5 4 0 0 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.9 CBY40034.1 - 0.22 11.9 4.4 16 5.9 0.1 4.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CBY40034.1 - 0.46 10.5 10.9 6.6 6.8 0.7 4.0 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Chromo PF00385.24 CBY40037.1 - 2.2e-15 56.3 0.1 3.5e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.31 CBY40038.1 - 0.0015 18.6 0.1 0.0043 17.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TFIID_20kDa PF03847.13 CBY40039.1 - 4.8e-21 75.0 0.2 7.3e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 CBY40039.1 - 0.00043 20.6 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY40039.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBY40039.1 - 0.0028 17.7 0.0 0.0043 17.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CBY40039.1 - 0.0062 16.6 0.1 0.016 15.3 0.0 1.7 2 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit PUF PF00806.19 CBY40040.1 - 7.5e-68 220.6 12.7 3.7e-09 35.8 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CBY40040.1 - 0.0059 17.0 0.4 5.4 7.3 0.1 4.1 2 1 1 4 4 4 1 CPL (NUC119) domain Importin_rep_3 PF18806.1 CBY40040.1 - 0.03 14.4 0.1 0.39 10.8 0.0 2.8 1 1 0 2 2 2 0 Importin 13 repeat Ku_PK_bind PF08785.11 CBY40040.1 - 0.12 12.5 2.2 6.7 6.9 0.0 3.5 4 0 0 4 4 4 0 Ku C terminal domain like TBPIP PF07106.13 CBY40040.1 - 0.3 11.1 3.6 6 6.9 0.7 4.2 3 2 1 4 4 4 0 TBPIP/Hop2 winged helix domain Filament PF00038.21 CBY40042.1 - 1.2e-89 301.0 46.9 1.5e-89 300.7 46.9 1.1 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 CBY40042.1 - 7.3e-09 35.8 44.6 0.0014 18.7 16.0 4.7 3 1 0 3 3 3 3 TPR/MLP1/MLP2-like protein GAS PF13851.6 CBY40042.1 - 0.0012 18.3 45.2 0.24 10.7 2.8 3.3 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Filament_head PF04732.14 CBY40042.1 - 0.0012 19.6 7.9 0.0012 19.6 7.9 1.8 2 0 0 2 2 1 1 Intermediate filament head (DNA binding) region Myosin_tail_1 PF01576.19 CBY40042.1 - 0.0025 15.7 44.1 0.078 10.8 16.1 2.0 1 1 1 2 2 2 2 Myosin tail Spc7 PF08317.11 CBY40042.1 - 0.0028 16.6 39.7 0.04 12.8 10.0 2.5 1 1 1 2 2 2 2 Spc7 kinetochore protein FAM184 PF15665.5 CBY40042.1 - 0.0079 16.0 40.0 1.8 8.3 15.1 3.4 1 1 2 3 3 3 3 Family with sequence similarity 184, A and B RNR_N PF08343.10 CBY40042.1 - 0.013 15.5 8.8 0.65 10.1 0.4 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal DUF1664 PF07889.12 CBY40042.1 - 0.014 15.4 20.8 1.7 8.7 3.4 4.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 CBY40042.1 - 0.048 13.4 38.7 1.4 8.6 23.5 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 NPV_P10 PF05531.12 CBY40042.1 - 0.057 13.9 8.9 0.56 10.7 0.1 4.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 CBY40042.1 - 0.076 12.5 42.8 0.65 9.4 11.8 2.7 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal CCDC92 PF14916.6 CBY40042.1 - 0.13 12.0 13.7 0.56 10.0 0.0 4.9 5 0 0 5 5 4 0 Coiled-coil domain of unknown function XdhC_C PF13478.6 CBY40042.1 - 0.16 12.5 0.3 0.58 10.7 0.1 2.1 2 0 0 2 2 1 0 XdhC Rossmann domain BLOC1_2 PF10046.9 CBY40042.1 - 0.37 11.1 35.4 0.08 13.2 3.9 5.3 3 2 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CBY40042.1 - 0.48 10.5 9.9 1.3 9.1 2.5 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KASH_CCD PF14662.6 CBY40042.1 - 0.63 9.8 43.7 0.03 14.1 13.3 4.1 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4515 PF14988.6 CBY40042.1 - 0.65 9.8 41.1 0.17 11.7 3.1 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4515) PSI_PsaF PF02507.15 CBY40042.1 - 0.87 9.4 6.6 14 5.4 0.0 4.0 3 1 3 6 6 6 0 Photosystem I reaction centre subunit III Taxilin PF09728.9 CBY40042.1 - 1 8.4 42.3 2.1 7.4 29.9 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 CBY40042.1 - 1.1 9.3 43.4 0.19 11.8 1.3 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Allexi_40kDa PF05549.11 CBY40042.1 - 1.5 8.3 15.2 0.5 9.8 1.9 3.1 1 1 3 4 4 4 0 Allexivirus 40kDa protein Mt_ATP-synt_D PF05873.12 CBY40042.1 - 2.1 8.2 23.4 0.29 11.0 2.2 3.7 1 1 3 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) DHR10 PF18595.1 CBY40042.1 - 2.2 8.4 43.4 0.47 10.5 7.4 5.2 3 2 2 5 5 5 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 CBY40042.1 - 2.8 8.1 31.6 1.2 9.3 3.2 4.4 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF3698 PF12479.8 CBY40042.1 - 2.9 8.5 9.8 0.21 12.2 0.8 2.8 3 1 1 4 4 2 0 Protein of unknown function (DUF3698) DUF4407 PF14362.6 CBY40042.1 - 2.9 7.1 31.2 0.097 12.0 9.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 CBY40042.1 - 3 6.6 39.6 5.9 5.6 18.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ADIP PF11559.8 CBY40042.1 - 3.2 7.8 39.9 0.85 9.7 6.2 4.7 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.19 CBY40042.1 - 3.6 5.4 31.4 2.6 5.8 14.1 2.7 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.11 CBY40042.1 - 4 7.2 14.3 0.15 11.9 2.9 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) YabA PF06156.13 CBY40042.1 - 4.3 8.0 39.1 1 10.0 3.4 5.7 1 1 4 5 5 5 0 Initiation control protein YabA GIT_CC PF16559.5 CBY40042.1 - 4.3 7.3 18.2 7.2 6.6 0.3 5.7 4 2 2 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 CBY40042.1 - 4.4 7.4 25.0 0.34 11.0 2.0 6.2 4 2 1 5 5 5 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 CBY40042.1 - 4.7 7.4 43.5 0.77 10.0 9.4 4.1 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 CBY40042.1 - 5.5 6.0 32.0 0.01 14.9 5.8 3.3 1 1 1 2 2 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 CBY40042.1 - 5.8 7.1 46.7 1.2 9.3 4.0 4.5 2 2 1 3 3 2 0 Autophagy protein 16 (ATG16) Syntaxin_2 PF14523.6 CBY40042.1 - 6.2 7.3 23.0 0.043 14.2 3.9 4.1 1 1 2 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 CBY40042.1 - 7.1 5.8 40.7 1.9 7.7 3.6 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) Myb_DNA-bind_7 PF15963.5 CBY40042.1 - 7.4 6.5 9.4 0.69 9.9 2.4 2.7 2 0 0 2 2 2 0 Myb DNA-binding like Mis14 PF08641.12 CBY40042.1 - 7.7 6.8 34.4 0.048 14.0 12.9 4.1 2 1 2 4 4 3 0 Kinetochore protein Mis14 like DUF2205 PF10224.9 CBY40042.1 - 8.7 6.4 23.0 2.2 8.3 0.3 5.8 3 3 3 6 6 6 0 Short coiled-coil protein Lebercilin PF15619.6 CBY40042.1 - 9.8 5.8 47.0 4.4 6.9 2.8 4.3 2 2 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Lectin_N PF03954.14 CBY40042.1 - 9.9 5.9 12.8 5.6 6.7 0.4 4.0 2 2 0 2 2 2 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 CBY40043.1 - 0.16 12.5 1.4 0.39 11.2 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 CBY40043.1 - 0.3 9.0 9.0 0.38 8.6 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.18 CBY40043.1 - 1.5 8.0 9.7 2.3 7.5 9.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF572 PF04502.13 CBY40043.1 - 2.1 7.9 17.7 2.5 7.6 17.2 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF572) Fib_alpha PF08702.10 CBY40043.1 - 4.4 7.5 12.0 0.53 10.5 6.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 CBY40043.1 - 8.6 4.7 8.9 8 4.9 8.0 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 CBY40043.1 - 9.4 4.7 8.6 7.8 5.0 7.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A MRI PF15325.6 CBY40043.1 - 9.8 7.3 10.2 0.34 12.0 2.4 2.4 3 0 0 3 3 3 0 Modulator of retrovirus infection Pkinase PF00069.25 CBY40045.1 - 2.7e-09 36.8 0.4 2.7e-09 36.8 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40045.1 - 3.7e-07 29.7 0.9 6.6e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.29 CBY40047.1 - 4.7e-41 140.3 0.0 1.1e-40 139.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY40047.1 - 3.8e-09 36.2 0.0 8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBY40047.1 - 0.00021 21.3 0.1 0.0011 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY40047.1 - 0.00029 21.1 0.1 0.031 14.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CBY40047.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBY40047.1 - 0.0017 18.8 0.1 0.07 13.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY40047.1 - 0.0026 17.0 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBY40047.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY40047.1 - 0.0051 17.0 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBY40047.1 - 0.025 14.1 0.0 0.065 12.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBY40047.1 - 0.029 14.8 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 CBY40047.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBY40047.1 - 0.036 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBY40047.1 - 0.064 13.0 0.2 0.3 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 CBY40047.1 - 0.092 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CBY40047.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CBY40047.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY40047.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Rx_N PF18052.1 CBY40048.1 - 0.1 12.9 1.0 14 6.1 0.0 2.9 3 0 0 3 3 3 0 Rx N-terminal domain MFS_1 PF07690.16 CBY40049.1 - 7.9e-12 44.8 10.6 6.5e-09 35.2 10.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CBY40051.1 - 1.2e-34 119.9 0.0 1.7e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40051.1 - 2.9e-28 98.9 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY40051.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY40051.1 - 0.076 12.3 0.0 0.28 10.5 0.0 1.7 1 1 1 2 2 2 0 Kinase-like FERM_M PF00373.18 CBY40052.1 - 5.9e-07 29.9 0.0 9.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 FERM central domain PID PF00640.23 CBY40052.1 - 0.0019 18.2 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) Arm PF00514.23 CBY40053.1 - 0.027 14.5 9.0 1.9 8.6 0.0 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CBY40053.1 - 0.12 12.4 0.5 0.84 9.8 0.1 2.5 2 1 0 2 2 2 0 V-ATPase subunit H zf-met PF12874.7 CBY40054.1 - 6.1e-11 42.3 11.1 1.6e-06 28.3 2.0 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY40054.1 - 3.5e-10 39.9 11.8 3.4e-06 27.2 2.5 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CBY40054.1 - 8.8e-05 22.8 8.6 0.00087 19.6 0.6 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CBY40054.1 - 0.0001 22.7 6.4 0.0004 20.8 1.6 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-U1 PF06220.12 CBY40054.1 - 0.00054 19.7 4.6 0.0049 16.6 0.1 2.4 2 1 0 2 2 2 1 U1 zinc finger AKAP95 PF04988.12 CBY40054.1 - 0.015 15.6 5.7 0.16 12.2 0.4 2.1 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 CBY40054.1 - 0.029 15.2 6.5 2.3 9.3 1.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4093 PF13331.6 CBY40054.1 - 0.078 13.4 0.8 0.36 11.3 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4093) Rpr2 PF04032.16 CBY40054.1 - 0.11 12.9 5.0 0.23 11.8 2.4 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.14 CBY40054.1 - 0.12 12.8 1.4 1 9.7 1.7 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme CPP1-like PF11833.8 CBY40055.1 - 0.0017 18.0 2.1 0.003 17.3 2.1 1.4 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4064 PF13273.6 CBY40055.1 - 0.0093 16.2 2.5 0.39 11.0 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4064) YbjM PF11045.8 CBY40055.1 - 0.019 15.1 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae DsbD_2 PF13386.6 CBY40055.1 - 0.019 14.9 0.5 0.026 14.5 0.5 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Myb_DNA-binding PF00249.31 CBY40056.1 - 9.3e-41 137.8 24.9 5.6e-13 48.9 0.9 6.1 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY40056.1 - 1.7e-32 111.5 17.9 1.1e-06 28.8 1.0 6.3 5 1 0 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.8 CBY40056.1 - 1.5e-05 25.0 3.9 2.4 8.3 0.2 5.2 2 2 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 CBY40056.1 - 6.6e-05 23.0 0.2 0.9 9.8 0.1 3.8 3 1 1 4 4 4 2 Rap1 Myb domain SLIDE PF09111.10 CBY40056.1 - 0.0014 18.6 1.5 1.2 9.2 0.0 4.1 2 2 2 4 4 4 2 SLIDE RIFIN PF02009.16 CBY40058.1 - 0.006 16.5 0.2 0.0078 16.1 0.2 1.1 1 0 0 1 1 1 1 Rifin CemA PF03040.14 CBY40058.1 - 0.031 14.2 0.6 0.039 13.9 0.6 1.1 1 0 0 1 1 1 0 CemA family DUF3951 PF13131.6 CBY40058.1 - 0.096 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Peptidase_C48 PF02902.19 CBY40059.1 - 1.5e-33 116.5 0.3 2.6e-33 115.7 0.3 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GCFC PF07842.12 CBY40060.1 - 2.2e-45 155.4 20.0 2.5e-45 155.2 20.0 1.0 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Xpo1 PF08389.12 CBY40060.1 - 0.054 13.6 0.6 1.7 8.7 0.0 2.6 2 1 0 2 2 2 0 Exportin 1-like protein RVT_1 PF00078.27 CBY40061.1 - 1.7e-29 103.0 0.3 1.1e-28 100.3 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ALIX_LYPXL_bnd PF13949.6 CBY40061.1 - 0.017 14.4 1.6 0.42 9.9 1.0 2.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DMP12 PF16779.5 CBY40061.1 - 0.088 12.8 0.1 0.5 10.4 0.1 2.3 1 0 0 1 1 1 0 DNA-mimic protein SBDS_C PF09377.10 CBY40061.1 - 0.13 12.2 0.8 0.41 10.7 0.2 2.1 2 0 0 2 2 2 0 SBDS protein C-terminal domain Shisa PF13908.6 CBY40062.1 - 0.021 15.1 0.3 0.041 14.1 0.0 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DHHC PF01529.20 CBY40062.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3566 PF12089.8 CBY40062.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) TMEM154 PF15102.6 CBY40062.1 - 0.097 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 CBY40062.1 - 0.7 9.9 3.5 0.84 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF1858 PF08984.11 CBY40063.1 - 0.15 12.2 0.0 0.61 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) ATG16 PF08614.11 CBY40064.1 - 0.0023 18.2 3.3 0.0056 16.9 3.3 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 CBY40064.1 - 0.013 14.6 1.9 0.021 14.0 1.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBY40064.1 - 0.022 14.1 0.4 0.026 13.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) E2F_CC-MB PF16421.5 CBY40064.1 - 0.036 14.4 1.0 0.49 10.8 0.1 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Cnn_1N PF07989.11 CBY40064.1 - 0.041 14.0 3.2 0.28 11.4 0.0 2.8 3 0 0 3 3 2 0 Centrosomin N-terminal motif 1 BST2 PF16716.5 CBY40064.1 - 0.092 13.3 3.8 2.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 TBPIP PF07106.13 CBY40064.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain GIT_CC PF16559.5 CBY40064.1 - 0.15 12.0 4.4 0.22 11.4 1.1 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 CBY40064.1 - 0.15 11.3 5.5 0.049 12.9 1.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Rho_Binding PF08912.11 CBY40064.1 - 0.17 12.7 0.8 0.17 12.7 0.8 2.3 2 0 0 2 2 2 0 Rho Binding PRKG1_interact PF15898.5 CBY40064.1 - 0.24 12.3 7.8 0.11 13.5 4.9 1.9 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain Prefoldin_2 PF01920.20 CBY40064.1 - 0.31 11.0 0.2 0.31 11.0 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.9 CBY40064.1 - 0.32 10.9 7.1 0.64 9.9 1.1 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 CBY40064.1 - 0.34 11.6 3.1 0.81 10.4 3.1 1.6 1 0 0 1 1 1 0 Initiation control protein YabA GAS PF13851.6 CBY40064.1 - 0.47 9.8 8.4 2.9 7.2 8.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 CBY40064.1 - 0.75 10.3 5.6 0.68 10.5 0.3 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region KLRAQ PF10205.9 CBY40064.1 - 1 9.6 6.3 1.8 8.8 3.6 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein JAKMIP_CC3 PF16034.5 CBY40064.1 - 1.5 8.7 8.0 0.6 10.0 0.8 2.7 2 1 1 3 3 3 0 JAKMIP CC3 domain bZIP_Maf PF03131.17 CBY40064.1 - 1.9 9.1 8.6 13 6.4 1.3 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor ZapB PF06005.12 CBY40064.1 - 2.3 8.7 7.3 17 5.9 7.3 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 CBY40064.1 - 2.5 8.0 8.7 0.61 9.9 1.6 3.0 1 1 1 2 2 2 0 Septum formation initiator CO_dh PF02552.16 CBY40065.1 - 0.11 12.3 0.5 0.13 12.0 0.5 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit CIDR1_gamma PF18562.1 CBY40065.1 - 1.1 9.5 6.5 2.3 8.4 6.5 1.7 1 1 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma DUF3523 PF12037.8 CBY40066.1 - 4.6e-16 59.0 28.5 6.5e-16 58.5 28.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 CBY40066.1 - 2.3e-08 34.5 0.2 2.6e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY40066.1 - 2.3e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBY40066.1 - 0.00028 20.7 0.6 0.00092 19.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CBY40066.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBY40066.1 - 0.0014 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBY40066.1 - 0.0027 18.1 0.0 0.0027 18.1 0.0 2.4 2 2 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 CBY40066.1 - 0.0033 17.4 0.0 0.0089 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CBY40066.1 - 0.0045 16.9 2.3 0.0053 16.7 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CBY40066.1 - 0.0046 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CBY40066.1 - 0.0091 15.7 0.1 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBY40066.1 - 0.021 15.0 0.2 0.087 12.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 CBY40066.1 - 0.043 14.1 1.8 0.061 13.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CBY40066.1 - 0.058 13.4 0.6 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CBY40066.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.9 2 1 1 3 3 2 0 AAA domain AAA_25 PF13481.6 CBY40066.1 - 0.14 11.7 0.9 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBY40066.1 - 0.3 10.8 0.0 0.3 10.8 0.0 3.2 2 1 0 2 2 1 0 AAA domain DEAD PF00270.29 CBY40067.1 - 1.2e-44 152.2 0.0 6.2e-44 149.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY40067.1 - 1.8e-16 60.4 0.0 3.9e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY40067.1 - 0.00012 22.1 0.0 0.00049 20.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBY40067.1 - 0.11 12.2 0.0 4.1 7.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CBY40067.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SRP72 PF08492.12 CBY40068.1 - 0.02 15.3 0.7 0.12 12.8 0.2 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain Astacin PF01400.24 CBY40069.1 - 1e-24 87.2 0.2 1.3e-24 86.9 0.2 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) MCM_OB PF17207.3 CBY40070.1 - 5.8e-34 116.6 1.0 5.8e-34 116.6 1.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_N PF14551.6 CBY40070.1 - 5.7e-18 65.4 0.3 1e-17 64.6 0.3 1.4 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.23 CBY40070.1 - 7.6e-09 35.0 0.0 2e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain zf_UBZ PF18439.1 CBY40070.1 - 0.029 14.0 1.2 0.24 11.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger LRR_9 PF14580.6 CBY40071.1 - 2.2e-12 46.9 2.3 3.5e-12 46.2 2.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY40071.1 - 6e-10 39.2 9.5 1.7e-05 25.1 0.9 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY40071.1 - 1.8e-08 34.0 5.9 1.9e-08 33.9 1.3 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 CBY40071.1 - 2.4 8.4 7.7 59 4.1 0.4 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY40071.1 - 3.9 8.4 10.3 1.5e+02 3.6 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat Lectin_C PF00059.21 CBY40072.1 - 8.5e-16 58.6 0.9 1.8e-15 57.6 0.9 1.6 1 0 0 1 1 1 1 Lectin C-type domain Somatomedin_B PF01033.17 CBY40072.1 - 2.4 8.6 30.7 0.36 11.3 24.1 3.0 2 2 0 2 2 2 0 Somatomedin B domain Pkinase PF00069.25 CBY40073.1 - 1.7e-64 217.7 0.0 4.5e-64 216.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40073.1 - 2.6e-37 128.5 0.0 4.1e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CBY40073.1 - 7.9e-30 102.5 28.3 7.6e-16 57.7 7.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CBY40073.1 - 4.8e-09 36.4 0.1 1.2e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 CBY40073.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY40073.1 - 0.0045 16.3 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBY40073.1 - 0.025 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prim_Zn_Ribbon PF08273.12 CBY40073.1 - 0.04 14.2 2.4 0.72 10.2 0.1 2.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase C1_2 PF03107.16 CBY40073.1 - 0.074 13.4 17.6 0.49 10.8 3.1 2.6 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 CBY40073.1 - 0.84 9.8 15.0 0.088 12.9 4.8 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 CBY40073.1 - 6.2 6.8 25.0 9.7 6.2 11.0 2.6 2 0 0 2 2 2 0 PHD-finger MFS_1 PF07690.16 CBY40076.1 - 2.2e-15 56.5 0.8 2.9e-15 56.1 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CPSase_L_D2 PF02786.17 CBY40078.1 - 2.3e-72 242.9 0.0 4.1e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBY40078.1 - 5.8e-47 158.8 0.6 4e-45 152.9 0.1 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBY40078.1 - 1.8e-21 76.3 0.0 4.1e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CBY40078.1 - 7.4e-12 45.2 0.0 2.9e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBY40078.1 - 1.2e-09 37.9 0.1 2.9e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 CBY40078.1 - 9.2e-06 25.4 0.0 8.6e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CBY40078.1 - 0.00036 20.6 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 CBY40078.1 - 0.0027 17.5 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MinE PF03776.14 CBY40078.1 - 0.0034 17.3 0.5 0.012 15.6 0.2 2.0 2 0 0 2 2 2 1 Septum formation topological specificity factor MinE ATPgrasp_ST PF14397.6 CBY40078.1 - 0.0048 16.2 0.1 0.19 10.9 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 CBY40078.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain zf-C2H2_4 PF13894.6 CBY40079.1 - 1.7e-05 25.3 28.0 0.0014 19.3 0.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY40079.1 - 0.019 15.3 4.4 0.019 15.3 4.4 4.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CBY40079.1 - 0.082 13.2 7.7 0.033 14.5 2.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 CBY40079.1 - 0.12 12.9 0.4 0.12 12.9 0.4 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY40079.1 - 0.14 12.5 16.8 1.4 9.3 0.9 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 CBY40079.1 - 1.1 9.3 11.1 5 7.2 3.2 3.4 3 1 0 3 3 3 0 CpXC protein zf-C2H2_6 PF13912.6 CBY40079.1 - 1.3 9.2 15.0 0.39 10.8 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Xan_ur_permease PF00860.20 CBY40080.1 - 2.5e-12 46.2 2.7 3.3e-12 45.8 2.7 1.1 1 0 0 1 1 1 1 Permease family EGF_3 PF12947.7 CBY40082.1 - 1.3e-09 38.1 8.0 1.3e-09 38.1 8.0 2.1 2 0 0 2 2 2 1 EGF domain EGF_CA PF07645.15 CBY40082.1 - 7.4e-05 22.9 8.9 7.4e-05 22.9 8.9 2.2 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF PF00008.27 CBY40082.1 - 0.0013 19.0 3.1 0.0028 17.9 3.1 1.6 1 0 0 1 1 1 1 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY40082.1 - 0.0018 18.6 6.9 0.003 17.8 6.9 1.4 1 0 0 1 1 1 1 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 CBY40082.1 - 0.1 12.6 5.7 0.21 11.7 5.7 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY40082.1 - 2.6 8.4 11.3 0.19 12.0 6.3 1.7 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site MEA1 PF06910.11 CBY40083.1 - 6.3e-11 43.0 4.1 1.6e-10 41.7 4.1 1.7 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) PMSI1 PF15322.6 CBY40083.1 - 0.071 12.5 1.8 0.078 12.4 1.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RVT_1 PF00078.27 CBY40085.1 - 6.6e-19 68.3 0.0 1.9e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY40085.1 - 2e-15 57.0 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CBY40085.1 - 5.3e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY40085.1 - 0.00065 19.9 0.0 0.0028 17.9 0.0 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY40085.1 - 0.0043 17.1 2.0 0.0091 16.1 2.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain ANAPC2 PF08672.11 CBY40085.1 - 0.027 15.0 0.8 7.4 7.2 0.0 3.7 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 Presenilin PF01080.17 CBY40085.1 - 3.6 6.2 8.7 6 5.5 8.7 1.2 1 0 0 1 1 1 0 Presenilin RhoGEF PF00621.20 CBY40086.1 - 2.1e-39 135.6 1.0 3.2e-39 135.0 1.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Pkinase PF00069.25 CBY40087.1 - 6.2e-70 235.6 0.0 7e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40087.1 - 4.9e-35 121.1 0.0 6.2e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY40087.1 - 0.00011 21.3 0.0 0.00032 19.8 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY40087.1 - 0.0034 17.4 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY40087.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CBY40087.1 - 0.04 13.2 0.0 0.1 11.9 0.0 1.7 2 1 0 2 2 2 0 Kinase-like GAS2 PF02187.17 CBY40088.1 - 9.8e-32 108.9 0.3 1.9e-31 107.9 0.3 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EF-hand_1 PF00036.32 CBY40088.1 - 2.8e-08 32.7 1.1 3.5e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY40088.1 - 2.4e-07 30.1 0.2 2.1e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY40088.1 - 3.6e-07 30.5 1.9 5.8e-07 29.9 0.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair Spectrin PF00435.21 CBY40088.1 - 0.0012 19.3 0.2 0.0026 18.2 0.2 1.6 1 0 0 1 1 1 1 Spectrin repeat EF-hand_8 PF13833.6 CBY40088.1 - 0.0018 18.1 0.2 0.0052 16.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair DUF608 PF04685.13 CBY40088.1 - 0.023 13.8 0.4 0.45 9.6 0.1 2.1 1 1 1 2 2 2 0 Glycosyl-hydrolase family 116, catalytic region Pkinase PF00069.25 CBY40089.1 - 9.6e-41 139.9 0.1 1.3e-40 139.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40089.1 - 6.7e-20 71.4 0.0 9.6e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_48 PF17906.1 CBY40089.1 - 0.014 15.5 0.4 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Vg_Tdu PF07545.14 CBY40089.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Phospholip_A2_1 PF00068.19 CBY40090.1 - 8.1e-14 52.0 6.4 8.1e-14 52.0 6.4 2.0 2 0 0 2 2 2 1 Phospholipase A2 GGDEF_2 PF17853.1 CBY40090.1 - 0.049 13.9 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 GGDEF-like domain Pou PF00157.17 CBY40092.1 - 2.7e-37 126.6 0.1 1e-36 124.7 0.0 2.1 3 0 0 3 3 3 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY40092.1 - 1.6e-12 47.0 1.0 3.2e-12 46.1 0.5 1.8 2 0 0 2 2 2 1 Homeodomain Mfa1 PF17445.2 CBY40092.1 - 2.1 8.4 9.6 0.085 12.9 2.3 2.6 2 0 0 2 2 2 0 Mating factor A1 dCMP_cyt_deam_1 PF00383.23 CBY40093.1 - 8.2e-13 48.1 0.2 2.7e-12 46.5 0.2 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY40093.1 - 5.2e-07 29.9 1.1 2.1e-06 27.9 0.3 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region PhaC_N PF07167.13 CBY40093.1 - 0.0072 16.0 0.1 0.01 15.5 0.1 1.2 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus LmjF365940-deam PF14421.6 CBY40093.1 - 0.023 14.3 2.4 1.6 8.3 2.4 2.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases DUF4201 PF13870.6 CBY40094.1 - 0.00076 19.3 18.0 0.00076 19.3 18.0 13.2 3 3 8 13 13 13 3 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.8 CBY40094.1 - 0.019 15.0 1.5 0.019 15.0 1.5 19.8 8 6 9 19 19 19 0 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.19 CBY40094.1 - 0.39 8.5 239.8 0.0091 13.9 49.4 6.1 2 1 3 5 5 5 0 Myosin tail ARID PF01388.21 CBY40098.1 - 4.1e-21 75.4 0.0 1e-20 74.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TRAPPC9-Trs120 PF08626.11 CBY40100.1 - 2.7e-36 124.5 3.9 3.5e-24 84.3 0.2 2.7 3 1 0 3 3 3 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CBY40100.1 - 0.012 15.9 4.4 0.48 10.8 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1441 PF07278.11 CBY40100.1 - 0.032 14.1 0.1 11 6.0 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1441) Na_Ca_ex PF01699.24 CBY40101.1 - 3.7e-29 101.6 12.3 4.1e-29 101.5 12.3 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Cadherin_C_2 PF16492.5 CBY40101.1 - 0.0028 18.4 1.0 0.0044 17.7 1.0 1.4 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal DUF2891 PF11199.8 CBY40102.1 - 0.059 12.3 0.0 0.065 12.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) ATP-grasp_6 PF18419.1 CBY40103.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain DUF3285 PF11688.8 CBY40104.1 - 0.24 11.3 0.7 0.42 10.6 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Chordopox_A13L PF05961.11 CBY40106.1 - 0.024 14.9 1.1 0.028 14.7 0.2 1.6 2 1 0 2 2 2 0 Chordopoxvirus A13L protein Phage_holin_2_4 PF16082.5 CBY40106.1 - 0.026 14.2 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PspB PF06667.12 CBY40106.1 - 0.041 13.9 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B OATP PF03137.20 CBY40106.1 - 0.056 11.7 0.2 0.065 11.5 0.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF5330 PF17264.2 CBY40107.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5330) TipAS PF07739.13 CBY40107.1 - 0.1 13.2 0.1 0.24 12.0 0.1 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Alpha-amyl_C2 PF07821.12 CBY40108.1 - 0.087 13.1 2.9 15 5.9 0.1 3.0 3 0 0 3 3 3 0 Alpha-amylase C-terminal beta-sheet domain LAT2 PF15703.5 CBY40108.1 - 0.16 11.9 1.9 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells family member 2 Penicillinase_R PF03965.16 CBY40108.1 - 0.23 11.8 0.8 0.5 10.7 0.1 1.9 2 0 0 2 2 2 0 Penicillinase repressor DUF432 PF04254.13 CBY40109.1 - 0.0083 16.3 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF432) CN_hydrolase PF00795.22 CBY40110.1 - 7.7e-54 182.8 0.0 9.6e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sec1 PF00995.23 CBY40111.1 - 2.1e-21 76.8 0.0 2.4e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.20 CBY40113.1 - 0.049 14.1 1.2 0.19 12.2 1.2 2.1 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain MPP6 PF10175.9 CBY40114.1 - 5.9e-12 46.2 5.8 5.9e-12 46.2 5.8 1.8 1 1 1 2 2 2 1 M-phase phosphoprotein 6 ICMT PF04140.14 CBY40115.1 - 3.7e-21 75.4 0.0 4.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBY40115.1 - 4e-07 30.4 0.0 4.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CBY40115.1 - 4.3e-05 22.4 0.4 5.4e-05 22.1 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CBY40115.1 - 0.0013 18.3 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) QH-AmDH_gamma PF08992.11 CBY40115.1 - 0.071 13.1 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Cyclin_N PF00134.23 CBY40117.1 - 1.8e-09 37.4 1.4 6.9e-08 32.3 0.2 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 CBY40117.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 2.0 2 1 0 2 2 2 1 Transcription factor TFIIB repeat PHM7_ext PF12621.8 CBY40118.1 - 0.1 12.8 0.7 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter DUF3475 PF11961.8 CBY40119.1 - 0.12 12.5 2.2 0.23 11.5 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) RSRP PF17069.5 CBY40119.1 - 3.9 7.0 17.8 5 6.6 17.8 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 zf-CCCH PF00642.24 CBY40122.1 - 9.1e-19 66.9 32.2 2.6e-06 27.2 1.0 5.5 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY40122.1 - 2.2e-18 65.7 44.8 6.8e-07 29.1 2.0 6.3 6 0 0 6 6 6 4 Zinc finger domain Torus PF16131.5 CBY40122.1 - 3.2e-14 53.5 27.7 0.00031 21.4 0.5 5.1 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 CBY40122.1 - 2.7e-12 46.2 24.8 1.4e-05 24.8 0.4 5.2 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBY40122.1 - 3.9e-09 36.7 26.1 7.6e-06 26.1 9.5 3.0 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CBY40122.1 - 0.0042 17.5 34.9 0.17 12.4 2.1 6.1 5 1 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 CBY40122.1 - 0.02 14.9 4.3 0.02 14.9 4.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-C3H1 PF10650.9 CBY40122.1 - 0.58 9.9 14.9 0.99 9.2 0.2 4.4 4 0 0 4 4 4 0 Putative zinc-finger domain KH_1 PF00013.29 CBY40123.1 - 9e-49 163.2 14.6 1.3e-12 47.4 0.2 4.1 4 0 0 4 4 4 4 KH domain KH_2 PF07650.17 CBY40123.1 - 8.6e-13 47.9 8.0 0.032 14.0 0.0 4.5 4 0 0 4 4 4 4 KH domain KH_4 PF13083.6 CBY40123.1 - 3.8e-11 42.7 5.3 0.0025 17.6 0.1 4.5 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 CBY40123.1 - 1e-07 31.9 6.7 0.66 10.1 0.0 4.5 4 0 0 4 4 4 3 NusA-like KH domain MOEP19 PF16005.5 CBY40123.1 - 6e-05 23.0 0.0 0.35 10.9 0.0 3.9 3 1 1 4 4 4 1 KH-like RNA-binding domain DbpA PF03880.15 CBY40123.1 - 0.18 11.8 2.8 12 6.0 0.0 2.9 3 0 0 3 3 3 0 DbpA RNA binding domain ANAPC4_WD40 PF12894.7 CBY40125.1 - 4.7e-23 81.3 1.5 1.5e-05 25.2 0.0 6.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY40125.1 - 1.7e-21 76.1 12.0 0.00018 22.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CBY40125.1 - 5.3e-06 25.2 0.4 0.0021 16.6 0.4 2.4 1 1 2 3 3 3 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CBY40125.1 - 0.00038 19.6 0.1 0.2 10.7 0.0 2.7 1 1 2 3 3 3 2 Coatomer WD associated region Peptidase_S9_N PF02897.15 CBY40125.1 - 0.0013 17.6 1.4 2.4 6.8 0.0 3.5 2 1 1 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.8 CBY40125.1 - 0.0018 17.0 0.1 0.0049 15.6 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 IKI3 PF04762.12 CBY40125.1 - 0.0078 14.3 0.1 0.22 9.5 0.0 2.7 2 1 0 2 2 2 1 IKI3 family Me-amine-dh_H PF06433.11 CBY40125.1 - 0.038 12.9 0.0 0.58 9.0 0.0 2.7 2 1 1 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 CBY40125.1 - 0.18 11.8 0.0 47 4.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Connexin PF00029.19 CBY40126.1 - 1.1e-83 280.6 5.1 1.6e-83 280.1 5.1 1.2 1 0 0 1 1 1 1 Connexin DUF2207 PF09972.9 CBY40126.1 - 0.29 9.8 5.2 2.5 6.8 0.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.19 CBY40127.1 - 5.1e-85 285.4 0.0 6.3e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CBY40127.1 - 4.2e-25 88.9 0.0 6.7e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CBY40127.1 - 4.1e-05 22.8 0.0 7.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CBY40127.1 - 0.00025 20.7 0.1 0.0016 18.1 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY40127.1 - 0.0023 17.3 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY40127.1 - 0.0055 15.8 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CBY40127.1 - 0.01 15.1 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBY40127.1 - 0.018 15.3 0.1 0.043 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBY40127.1 - 0.044 12.5 0.0 0.54 8.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 CBY40127.1 - 0.22 11.8 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Mucin PF01456.17 CBY40129.1 - 0.08 12.9 4.3 0.11 12.5 4.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein EGF_CA PF07645.15 CBY40130.1 - 2.5e-86 283.6 353.9 1.9e-10 40.7 12.5 25.0 25 2 2 27 27 27 14 Calcium-binding EGF domain cEGF PF12662.7 CBY40130.1 - 2.8e-30 103.9 226.3 1.9e-06 27.7 2.8 25.2 26 0 0 26 26 26 13 Complement Clr-like EGF-like TIL PF01826.17 CBY40130.1 - 1.9e-22 79.2 316.5 6.2e-06 26.4 16.6 22.7 16 7 6 22 22 22 11 Trypsin Inhibitor like cysteine rich domain EGF_3 PF12947.7 CBY40130.1 - 1.6e-18 66.6 260.3 2.1e-05 24.6 6.9 22.2 23 2 0 23 23 23 14 EGF domain EGF PF00008.27 CBY40130.1 - 9.1e-06 25.9 250.6 0.08 13.3 6.8 24.8 25 0 0 25 25 25 13 EGF-like domain hEGF PF12661.7 CBY40130.1 - 4.2e-05 24.0 253.7 0.043 14.5 1.1 25.7 26 1 1 27 27 27 13 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY40130.1 - 0.0001 22.2 17.7 0.00013 21.9 6.1 21.6 22 1 1 23 23 23 9 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY40130.1 - 0.0012 19.1 19.6 0.0038 17.5 3.1 23.0 22 3 1 23 23 23 12 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY40130.1 - 0.0042 17.4 1.5 0.0042 17.4 1.5 21.2 21 1 0 21 21 21 9 Pvs28 EGF domain ASFV_J13L PF05568.11 CBY40131.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 African swine fever virus J13L protein TMEM154 PF15102.6 CBY40131.1 - 0.011 15.6 0.4 0.023 14.6 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.6 CBY40131.1 - 0.04 14.8 0.0 0.072 14.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 CBY40131.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator WD40 PF00400.32 CBY40133.1 - 2e-06 28.4 0.0 8.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY40133.1 - 0.071 12.1 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGEF PF00617.19 CBY40135.1 - 4.7e-38 131.1 1.9 1.8e-37 129.2 0.8 2.3 1 1 1 2 2 2 1 RasGEF domain Glyco_hydro_31 PF01055.26 CBY40136.1 - 1e-49 170.0 1.4 1.5e-49 169.4 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBY40136.1 - 0.039 14.3 0.8 0.14 12.5 0.1 2.3 3 0 0 3 3 3 0 Galactose mutarotase-like 2OG-FeII_Oxy PF03171.20 CBY40138.1 - 2.7e-10 40.7 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY40138.1 - 3.9e-05 24.4 0.1 7.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HEPN_LA2681 PF18733.1 CBY40138.1 - 0.00012 21.4 2.0 0.00025 20.4 1.9 1.6 1 1 0 1 1 1 1 LA2681-like HEPN DUF3909 PF13077.6 CBY40140.1 - 0.027 14.6 0.5 0.052 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF3502 PF12010.8 CBY40140.1 - 0.062 13.9 2.5 2.4 8.8 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) ABC_tran PF00005.27 CBY40141.1 - 5.9e-50 169.3 0.2 1.1e-23 84.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBY40141.1 - 7.9e-19 68.0 34.4 1.8e-10 40.5 15.1 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBY40141.1 - 7.4e-17 62.1 4.7 8.8e-08 32.3 0.0 4.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CBY40141.1 - 1.9e-10 40.9 0.6 6.6e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CBY40141.1 - 4.3e-08 32.8 0.4 0.0029 17.3 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY40141.1 - 7.6e-08 33.1 15.2 0.00058 20.4 0.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 CBY40141.1 - 1e-06 28.8 10.9 0.03 14.1 0.2 4.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 CBY40141.1 - 6.4e-06 26.7 0.3 0.16 12.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 CBY40141.1 - 1.6e-05 24.4 1.8 0.7 9.3 0.0 3.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBY40141.1 - 0.00065 20.0 0.3 2.2 8.5 0.1 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 CBY40141.1 - 0.0013 18.7 0.5 0.69 9.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 CBY40141.1 - 0.0027 17.8 2.1 0.45 10.6 0.2 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 CBY40141.1 - 0.0032 17.5 0.3 0.7 9.9 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CBY40141.1 - 0.018 15.4 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CBY40141.1 - 0.019 15.2 0.4 4.6 7.5 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 CBY40141.1 - 0.02 14.5 0.2 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBY40141.1 - 0.027 13.8 0.0 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CBY40141.1 - 0.034 13.9 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CBY40141.1 - 0.035 12.8 1.8 2 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 CBY40141.1 - 0.045 13.5 0.2 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.6 CBY40141.1 - 0.065 12.8 0.4 8.7 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBY40141.1 - 0.075 13.6 0.2 2.2 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBY40141.1 - 0.089 12.5 0.8 3.2 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBY40141.1 - 0.11 12.1 3.7 3.2 7.3 0.8 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 CBY40141.1 - 0.17 12.3 0.1 9.1 6.7 0.0 3.2 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 CBY40141.1 - 0.17 10.6 0.2 8.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_5 PF07728.14 CBY40141.1 - 0.21 11.6 1.0 11 6.0 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 CBY40141.1 - 0.23 11.0 1.3 10 5.6 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 CBY40141.1 - 0.25 10.9 1.4 7.8 6.1 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CBY40141.1 - 1.4 9.2 3.9 2.4 8.4 0.4 2.3 2 0 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.20 CBY40142.1 - 1.9e-75 253.9 0.1 2.9e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 CBY40142.1 - 1.1e-19 70.3 1.3 1.1e-19 70.3 1.3 2.3 1 1 2 3 3 3 1 WHEP-TRS domain tRNA_anti-codon PF01336.25 CBY40142.1 - 0.00025 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBY40142.1 - 0.0017 17.9 0.5 0.97 8.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.8 CBY40142.1 - 7.5 5.3 17.5 13 4.5 17.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NUP50 PF08911.11 CBY40143.1 - 6.9e-17 61.9 4.8 6.9e-17 61.9 4.8 3.5 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 CBY40143.1 - 1.2e-07 32.1 0.1 1.2e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 RanBP1 domain nsp9 PF08710.10 CBY40143.1 - 0.16 12.4 0.1 0.46 10.9 0.1 1.7 1 0 0 1 1 1 0 nsp9 replicase WD40 PF00400.32 CBY40144.1 - 2.5e-14 53.4 0.6 2.8e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 CBY40144.1 - 0.00086 18.7 0.0 0.0016 17.8 0.0 1.4 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 CBY40144.1 - 0.025 14.9 0.1 1.3 9.4 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Polysacc_syn_2C PF08485.10 CBY40144.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal Homeodomain PF00046.29 CBY40145.1 - 1.6e-21 75.8 2.6 1.6e-21 75.8 2.6 2.3 3 0 0 3 3 3 1 Homeodomain Transposase_21 PF02992.14 CBY40146.1 - 0.055 12.7 0.2 0.068 12.4 0.2 1.1 1 0 0 1 1 1 0 Transposase family tnp2 Tetraspanin PF00335.20 CBY40146.1 - 5.2 6.7 6.9 6.1 6.5 6.9 1.1 1 0 0 1 1 1 0 Tetraspanin family EGF_2 PF07974.13 CBY40147.1 - 1.6e-13 50.7 180.8 4.1e-05 23.9 13.3 12.2 12 1 1 13 13 13 7 EGF-like domain EGF PF00008.27 CBY40147.1 - 3.8e-07 30.3 33.5 7.2e-05 23.0 4.3 10.6 10 2 2 12 12 12 7 EGF-like domain Gal-3-0_sulfotr PF06990.11 CBY40148.1 - 1.6e-44 152.4 0.4 6.1e-43 147.2 0.4 2.1 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY40148.1 - 4.7e-06 26.7 6.9 4.9e-06 26.6 0.2 3.3 3 1 0 3 3 3 1 Sulfotransferase family FERM_N PF09379.10 CBY40148.1 - 0.015 15.2 0.4 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain Mannitol_dh_C PF08125.13 CBY40149.1 - 0.06 12.8 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain DEAD PF00270.29 CBY40150.1 - 1.8e-24 86.5 0.0 2.2e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 CBY40150.1 - 7.1e-19 68.1 0.2 1.2e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 CBY40150.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Neuralized Dicty_REP PF05086.12 CBY40153.1 - 0.02 12.9 1.3 0.023 12.7 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5435 PF17503.2 CBY40153.1 - 0.11 12.2 2.4 0.16 11.7 1.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5435) Mucin PF01456.17 CBY40153.1 - 3.8 7.5 25.9 6.5 6.7 25.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIE_alpha PF02002.17 CBY40155.1 - 0.0039 17.0 2.8 1.1 9.1 0.6 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit Sipho_Gp157 PF05565.11 CBY40155.1 - 0.016 15.3 0.2 0.016 15.3 0.2 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 Anticodon_1 PF08264.13 CBY40155.1 - 0.062 13.3 0.2 0.062 13.3 0.2 3.2 4 0 0 4 4 4 0 Anticodon-binding domain of tRNA Elf4 PF07011.11 CBY40155.1 - 0.35 10.8 5.1 19 5.3 0.1 4.0 3 1 1 4 4 4 0 Early Flowering 4 domain FapA PF03961.13 CBY40155.1 - 8.5 4.9 11.1 1.8 7.1 4.8 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A FGF PF00167.18 CBY40156.1 - 7.3e-25 87.5 0.0 9.8e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Fibroblast growth factor Trypsin PF00089.26 CBY40157.1 - 3.2e-40 138.3 0.0 5.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY40157.1 - 7.7e-06 26.3 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY40157.1 - 0.00015 22.7 0.0 0.00035 21.5 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain NOA36 PF06524.12 CBY40157.1 - 0.027 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 NOA36 protein ABC_membrane PF00664.23 CBY40158.1 - 3.1e-110 368.1 27.3 7.7e-54 183.2 1.7 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CBY40158.1 - 4.4e-70 234.5 0.1 8.5e-34 117.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBY40158.1 - 3e-17 62.8 0.4 1.6e-06 27.7 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY40158.1 - 8e-10 38.9 0.2 0.00021 21.2 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 CBY40158.1 - 2.8e-09 37.3 1.1 0.0027 18.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBY40158.1 - 6.2e-09 36.0 0.0 0.00018 21.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBY40158.1 - 3.7e-07 29.3 0.2 0.015 14.1 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 CBY40158.1 - 5.3e-07 30.2 2.6 0.0006 20.2 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CBY40158.1 - 2.8e-05 24.3 3.7 0.26 11.5 0.3 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBY40158.1 - 6e-05 22.7 0.4 0.4 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CBY40158.1 - 9.3e-05 21.8 0.0 0.57 9.4 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 CBY40158.1 - 0.00015 21.8 0.2 0.63 9.9 0.1 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 CBY40158.1 - 0.00024 20.9 0.8 0.35 10.5 0.1 3.3 3 1 0 3 3 3 2 AAA domain G-alpha PF00503.20 CBY40158.1 - 0.00073 18.8 1.4 0.72 8.9 0.0 2.5 3 0 0 3 3 3 2 G-protein alpha subunit AAA PF00004.29 CBY40158.1 - 0.00079 19.9 1.4 3.3 8.1 0.2 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBY40158.1 - 0.0014 18.6 0.1 0.58 10.1 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) PRK PF00485.18 CBY40158.1 - 0.0017 18.1 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CBY40158.1 - 0.0037 17.6 0.0 5.4 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 CBY40158.1 - 0.0038 16.8 0.1 4 7.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CBY40158.1 - 0.0039 16.7 0.1 0.54 9.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 CBY40158.1 - 0.0048 16.1 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CBY40158.1 - 0.019 15.5 0.0 4 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CBY40158.1 - 0.024 14.5 0.6 7.8 6.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_10 PF12846.7 CBY40158.1 - 0.028 13.3 0.0 2.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF2795 PF11387.8 CBY40158.1 - 0.032 14.5 0.1 3.1 8.1 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) ATP-synt_ab PF00006.25 CBY40158.1 - 0.064 12.9 0.4 9.4 5.8 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain tRNA_lig_kinase PF08303.11 CBY40158.1 - 0.092 12.8 0.1 6.7 6.8 0.0 2.7 2 0 0 2 2 2 0 tRNA ligase kinase domain MMR_HSR1 PF01926.23 CBY40158.1 - 0.093 12.8 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Tub_N PF16322.5 CBY40158.1 - 0.48 10.8 6.2 0.87 10.0 6.2 1.3 1 0 0 1 1 1 0 Tubby N-terminal AAA_23 PF13476.6 CBY40158.1 - 1.2 9.6 11.2 3.3 8.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain zf-C4 PF00105.18 CBY40159.1 - 6e-23 81.1 12.2 8.7e-23 80.6 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) zf-RING_4 PF14570.6 CBY40159.1 - 0.42 10.5 7.1 1.7 8.5 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY40159.1 - 2 8.8 10.9 4.1 7.8 8.5 2.2 1 1 1 2 2 2 0 Ring finger domain eIF-6 PF01912.18 CBY40162.1 - 4.6e-33 114.3 0.2 8.6e-33 113.4 0.1 1.5 2 0 0 2 2 2 1 eIF-6 family DUF3576 PF12100.8 CBY40162.1 - 0.097 12.8 0.1 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) RRM_1 PF00076.22 CBY40163.1 - 3.2e-19 68.5 0.0 3.8e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY40163.1 - 0.021 15.0 0.0 0.03 14.4 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif DUF4944 PF16302.5 CBY40163.1 - 0.031 14.3 0.0 0.035 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) RRM_occluded PF16842.5 CBY40163.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBY40163.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBY40163.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PROCT PF08084.11 CBY40163.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 PROCT (NUC072) domain Pro_isomerase PF00160.21 CBY40164.1 - 2e-43 148.4 0.1 2.5e-43 148.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_S1 PF05827.12 CBY40165.1 - 0.00087 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Herpes_BLLF1 PF05109.13 CBY40165.1 - 0.27 9.2 15.0 0.33 8.9 15.0 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TCR PF03638.15 CBY40166.1 - 7.9e-26 90.1 52.8 1.4e-13 50.8 19.7 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 CBY40166.1 - 0.004 17.3 16.4 0.004 17.3 16.4 2.6 2 0 0 2 2 2 1 CXC domain of E3 ubiquitin-protein ligase MSL2 TFIIA PF03153.13 CBY40166.1 - 0.33 10.9 12.6 0.4 10.6 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CoA_binding PF02629.19 CBY40167.1 - 5.2e-21 75.2 1.1 6.9e-21 74.7 1.1 1.2 1 0 0 1 1 1 1 CoA binding domain Lectin_C PF00059.21 CBY40168.1 - 3.3e-07 31.0 9.8 8.8e-07 29.6 9.8 1.7 1 1 0 1 1 1 1 Lectin C-type domain VioE PF18234.1 CBY40168.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE zf-C2H2 PF00096.26 CBY40169.1 - 1.1e-16 60.2 23.0 1.3e-05 25.3 3.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY40169.1 - 1.9e-14 53.3 24.7 4.7e-09 36.3 1.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY40169.1 - 3.8e-10 39.7 20.2 0.0022 18.7 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CBY40169.1 - 3.4e-05 24.1 6.1 6.4e-05 23.2 5.6 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CBY40169.1 - 0.0044 17.0 15.8 0.21 11.6 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 CBY40169.1 - 0.016 15.8 9.0 0.64 10.7 0.2 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain Ogr_Delta PF04606.12 CBY40169.1 - 0.022 14.7 2.7 1.3 9.0 0.1 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2HC_2 PF13913.6 CBY40169.1 - 0.046 13.6 10.5 0.13 12.2 0.9 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF4119 PF13494.6 CBY40169.1 - 0.061 13.5 0.0 0.39 10.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-met PF12874.7 CBY40169.1 - 0.21 12.0 5.0 4.2 7.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY40169.1 - 1.1 9.6 9.3 0.17 12.2 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CHORD PF04968.12 CBY40169.1 - 1.4 9.7 8.3 1.9 9.3 2.0 2.5 1 1 1 2 2 2 0 CHORD zf-C2H2_aberr PF17017.5 CBY40169.1 - 2.1 8.5 3.9 29 4.7 0.9 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Sulfatase_C PF14707.6 CBY40170.1 - 0.1 13.4 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1731 PF08338.11 CBY40170.1 - 0.21 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) Sulfatase PF00884.23 CBY40171.1 - 1.4e-35 123.2 0.1 1.8e-35 122.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase ABC_transp_aux PF09822.9 CBY40171.1 - 0.028 13.9 0.1 0.051 13.0 0.0 1.5 2 0 0 2 2 2 0 ABC-type uncharacterized transport system PsaM PF07465.13 CBY40171.1 - 0.028 14.1 0.2 0.054 13.2 0.2 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Asp-B-Hydro_N PF05279.11 CBY40172.1 - 1.3 9.0 29.4 2.1 8.4 29.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CBY40172.1 - 2.8 6.6 15.5 3.6 6.3 15.5 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 CBY40172.1 - 3.8 5.3 10.9 4.3 5.1 10.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF809 PF05663.11 CBY40173.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF809) DUF3012 PF11216.8 CBY40174.1 - 0.0098 15.9 0.1 0.026 14.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) PHZA_PHZB PF03284.13 CBY40174.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Sec10 PF07393.11 CBY40175.1 - 1.1e-07 30.7 0.1 1.4e-07 30.4 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 CBY40175.1 - 5.1e-07 29.0 0.1 6.7e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec6 PF06046.13 CBY40175.1 - 0.00026 19.5 0.2 0.0029 16.0 0.1 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec6 GlutR_dimer PF00745.20 CBY40175.1 - 0.045 14.2 0.5 1.5 9.3 0.0 2.6 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Skp1 PF01466.19 CBY40175.1 - 0.052 13.7 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain TraF_2 PF13729.6 CBY40175.1 - 0.14 11.5 0.2 0.44 9.9 0.2 1.4 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein LSM PF01423.22 CBY40176.1 - 5.9e-16 57.9 1.9 7.3e-16 57.6 1.9 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY40176.1 - 0.0011 18.6 0.4 0.0016 18.1 0.4 1.4 1 0 0 1 1 1 1 Hfq protein Sulfotransfer_2 PF03567.14 CBY40178.1 - 2.3e-19 70.3 1.3 3.1e-19 69.9 1.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Inos-1-P_synth PF01658.17 CBY40178.1 - 0.021 15.1 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase PheRS_DBD3 PF18553.1 CBY40178.1 - 0.16 12.3 0.0 0.7 10.2 0.0 2.1 2 0 0 2 2 2 0 PheRS DNA binding domain 3 VWA PF00092.28 CBY40179.1 - 9.3e-18 65.1 0.2 1.2e-17 64.7 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CBY40179.1 - 1.8e-08 34.5 3.7 1.8e-08 34.5 3.7 2.3 2 0 0 2 2 2 1 Thrombospondin type 1 domain Arf PF00025.21 CBY40180.1 - 2.2e-13 50.1 0.2 2.3e-13 50.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CBY40180.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CBY40180.1 - 0.021 15.0 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY40180.1 - 0.038 13.4 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBY40180.1 - 0.038 14.1 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 CBY40180.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Pkinase PF00069.25 CBY40181.1 - 7.8e-19 68.1 0.0 1.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40181.1 - 9.9e-18 64.4 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_35 PF01301.19 CBY40184.1 - 6.8e-100 334.7 0.5 9e-100 334.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY40184.1 - 1.6e-09 37.6 3.7 3.5e-09 36.5 0.1 2.9 3 1 0 3 3 3 1 Beta-galactosidase Kelch_5 PF13854.6 CBY40185.1 - 0.02 14.9 1.7 0.071 13.1 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CBY40185.1 - 0.026 14.5 0.4 4.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY40185.1 - 0.072 13.4 1.6 2.6 8.5 0.0 3.5 3 1 1 4 4 4 0 Kelch motif Mito_carr PF00153.27 CBY40186.1 - 3.8e-26 90.9 1.8 2.1e-22 78.8 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1 PF07690.16 CBY40187.1 - 2.8e-13 49.5 9.5 2.8e-13 49.5 9.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY40187.1 - 9.2e-07 28.1 1.8 9.2e-07 28.1 1.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 CBY40187.1 - 4.6e-06 25.7 5.9 5.6e-06 25.4 5.9 1.1 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.7 CBY40187.1 - 4e-05 22.7 7.4 0.00014 20.9 7.3 1.7 1 1 0 1 1 1 1 MFS_1 like family HLH PF00010.26 CBY40188.1 - 3.6e-12 46.1 0.5 6.1e-12 45.3 0.4 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HTH_51 PF18558.1 CBY40188.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 CBY40189.1 - 1.2e-56 191.9 0.0 6.2e-52 176.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY40189.1 - 6.8e-31 107.6 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 CBY40189.1 - 0.031 13.2 0.1 0.043 12.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY40189.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PAW PF04721.17 CBY40190.1 - 1.4e-28 100.0 0.7 1.4e-28 100.0 0.7 1.9 2 0 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW PUB PF09409.10 CBY40190.1 - 1.2e-17 63.7 0.0 3.3e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 CBY40190.1 - 6.6e-06 26.6 0.2 2.2e-05 24.9 0.2 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily PrmA PF06325.13 CBY40190.1 - 0.057 12.8 1.6 0.17 11.2 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Trypsin PF00089.26 CBY40192.1 - 3.9e-29 102.0 0.1 5.4e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 Trypsin Kelch_2 PF07646.15 CBY40192.1 - 1.3e-05 25.0 0.2 0.015 15.3 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 CBY40192.1 - 0.0015 18.4 0.3 0.015 15.3 0.2 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain DUF316 PF03761.15 CBY40192.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Kelch_5 PF13854.6 CBY40192.1 - 0.045 13.7 0.6 0.26 11.3 0.0 2.5 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY40192.1 - 0.049 13.9 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Kelch motif PH PF00169.29 CBY40194.1 - 1.4e-05 25.5 1.5 2.7e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 PH domain C1q PF00386.21 CBY40195.1 - 3.4e-05 24.1 0.1 7.6e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 C1q domain FliJ PF02050.16 CBY40195.1 - 0.0006 20.0 1.1 0.004 17.4 0.0 2.4 1 1 1 2 2 2 1 Flagellar FliJ protein DUF5082 PF16888.5 CBY40195.1 - 0.00094 19.5 6.9 0.0016 18.7 3.7 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 CBY40195.1 - 0.0019 18.3 4.3 0.55 10.3 4.3 2.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CBY40195.1 - 0.0024 17.9 5.1 0.58 10.2 1.2 2.7 1 1 1 3 3 3 3 Protein of unknown function (DUF1664) Flagellar_rod PF05149.12 CBY40195.1 - 0.0038 16.7 2.6 0.015 14.8 2.4 1.9 1 1 1 2 2 2 1 Paraflagellar rod protein BclA_C PF18573.1 CBY40195.1 - 0.006 16.5 0.5 0.012 15.5 0.5 1.4 1 0 0 1 1 1 1 BclA C-terminal domain Prominin PF05478.11 CBY40195.1 - 0.013 13.5 2.8 0.022 12.8 2.8 1.3 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 CBY40195.1 - 0.015 14.2 4.2 0.76 8.6 1.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 CBY40195.1 - 0.016 15.7 1.1 3 8.3 0.0 2.7 1 1 1 2 2 2 0 Snapin/Pallidin XhlA PF10779.9 CBY40195.1 - 0.026 14.7 2.6 0.99 9.7 0.1 2.9 2 1 0 2 2 2 0 Haemolysin XhlA Laminin_II PF06009.12 CBY40195.1 - 0.032 14.3 6.2 2.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 CBY40195.1 - 0.039 14.3 11.2 0.7 10.3 0.2 4.3 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) eIF-5a PF01287.20 CBY40195.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Sec34 PF04136.15 CBY40195.1 - 0.12 12.2 7.8 1.6 8.6 2.7 2.5 1 1 1 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 CBY40195.1 - 0.12 12.8 7.1 1.2 9.7 0.9 3.2 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 CBY40195.1 - 0.19 11.9 3.1 0.29 11.4 1.0 2.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 CBY40195.1 - 0.21 11.2 5.5 0.84 9.2 1.1 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF1690 PF07956.11 CBY40195.1 - 0.28 11.6 5.8 0.35 11.3 4.1 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Tropomyosin_1 PF12718.7 CBY40195.1 - 0.3 11.2 3.7 6 7.0 3.7 2.3 1 1 0 1 1 1 0 Tropomyosin like BST2 PF16716.5 CBY40195.1 - 0.4 11.3 5.3 0.13 12.8 0.7 2.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 HemX PF04375.14 CBY40195.1 - 0.41 9.9 5.5 4.1 6.6 0.2 2.6 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cluap1 PF10234.9 CBY40195.1 - 0.91 8.9 5.0 3.2 7.1 4.7 1.8 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF948 PF06103.11 CBY40195.1 - 1.3 9.4 5.5 9.4 6.6 0.9 3.0 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 CBY40195.1 - 2.4 7.4 7.5 18 4.5 0.1 2.5 2 1 0 3 3 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 CBY40195.1 - 2.8 8.1 8.7 22 5.2 2.7 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBY40195.1 - 3.1 6.9 5.2 6.1 6.0 1.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein PMC2NT PF08066.12 CBY40195.1 - 3.5 8.4 5.9 17 6.2 1.5 3.0 2 1 1 3 3 3 0 PMC2NT (NUC016) domain MscS_porin PF12795.7 CBY40195.1 - 5.3 6.5 8.8 1.4 8.4 5.2 1.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain LPP PF04728.13 CBY40195.1 - 8.5 6.9 8.5 3.1 8.2 0.9 3.0 3 0 0 3 3 2 0 Lipoprotein leucine-zipper LRR_8 PF13855.6 CBY40196.1 - 1.1e-31 108.4 18.4 2e-10 40.3 0.1 4.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 CBY40196.1 - 1e-13 51.4 0.0 1.5e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY40196.1 - 3.2e-13 49.6 15.0 0.00099 19.5 1.5 5.9 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBY40196.1 - 0.0015 18.8 5.5 55 4.9 0.0 6.6 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 CBY40196.1 - 0.0049 16.4 4.2 0.13 11.8 0.8 2.4 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBY40196.1 - 0.31 11.2 13.1 23 5.3 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Fibrinogen_C PF00147.18 CBY40197.1 - 1.4e-52 178.7 5.7 1.9e-52 178.2 5.7 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain DUF3829 PF12889.7 CBY40197.1 - 0.00054 19.5 2.4 0.00099 18.7 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) RPW8 PF05659.11 CBY40197.1 - 0.041 13.6 1.6 0.07 12.8 1.6 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 B3 PF02362.21 CBY40197.1 - 0.98 9.3 3.0 13 5.7 0.1 3.2 3 0 0 3 3 3 0 B3 DNA binding domain Prefoldin PF02996.17 CBY40198.1 - 8.2e-11 41.9 0.3 8.2e-11 41.9 0.3 2.4 2 1 1 3 3 3 1 Prefoldin subunit CoA_transf_3 PF02515.17 CBY40198.1 - 0.15 11.2 3.9 4.4 6.3 0.0 2.2 1 1 1 2 2 2 0 CoA-transferase family III DUF3926 PF13080.6 CBY40198.1 - 2.1 8.4 5.5 2.3 8.2 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) HMA PF00403.26 CBY40199.1 - 1.8e-06 28.3 0.6 2.7e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Baculo_LEF5_C PF11792.8 CBY40199.1 - 0.064 12.9 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain TFIIS_C PF01096.18 CBY40199.1 - 0.081 12.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PIG-S PF10510.9 CBY40200.1 - 1.1e-28 100.4 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Calcipressin PF04847.12 CBY40200.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Calcipressin Pkinase PF00069.25 CBY40201.1 - 2.4e-09 37.0 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40201.1 - 8.9e-08 31.7 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.24 CBY40201.1 - 9.9 6.2 6.2 1.1 9.2 1.2 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) T4_deiodinase PF00837.17 CBY40202.1 - 7.6e-29 100.7 0.0 8e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Nab2 PF11517.8 CBY40204.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) ABC_tran PF00005.27 CBY40205.1 - 7e-31 107.6 0.0 2.6e-15 57.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CBY40205.1 - 1.4e-13 50.4 6.9 3e-13 49.3 6.9 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CBY40205.1 - 7.7e-10 38.6 2.9 0.0032 16.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBY40205.1 - 3.5e-09 36.9 3.8 0.19 11.5 1.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CBY40205.1 - 1.1e-07 31.3 3.6 1.1e-07 31.3 3.6 2.5 3 0 0 3 3 3 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CBY40205.1 - 2.1e-06 27.7 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY40205.1 - 6e-06 26.7 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBY40205.1 - 9.9e-06 25.5 0.1 0.043 13.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBY40205.1 - 5.4e-05 23.5 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBY40205.1 - 9.5e-05 22.4 0.0 0.097 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CBY40205.1 - 0.00011 22.2 0.0 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_7 PF12838.7 CBY40205.1 - 0.00024 21.6 7.6 0.00094 19.7 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBY40205.1 - 0.00033 20.6 12.5 0.00048 20.1 2.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 CBY40205.1 - 0.00037 20.2 0.1 0.55 10.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY40205.1 - 0.0004 20.9 0.1 0.074 13.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBY40205.1 - 0.0004 20.3 0.2 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 CBY40205.1 - 0.00046 20.6 0.0 0.28 11.6 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBY40205.1 - 0.00072 19.3 0.1 0.27 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CBY40205.1 - 0.0018 18.8 0.0 1.7 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBY40205.1 - 0.0019 18.3 0.0 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY40205.1 - 0.0034 17.8 1.4 3.8 8.0 0.0 3.1 3 1 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 CBY40205.1 - 0.0036 17.6 0.1 0.74 10.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 CBY40205.1 - 0.004 17.2 1.0 0.004 17.2 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 CBY40205.1 - 0.005 17.0 12.6 0.01 16.0 12.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY40205.1 - 0.0054 16.8 1.5 0.0054 16.8 1.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_30 PF13604.6 CBY40205.1 - 0.0057 16.4 0.9 0.75 9.5 0.1 2.9 4 0 0 4 4 2 1 AAA domain Fer4_21 PF14697.6 CBY40205.1 - 0.0061 16.7 13.6 0.02 15.0 13.7 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.22 CBY40205.1 - 0.0096 15.6 2.8 0.28 10.8 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBY40205.1 - 0.017 14.7 0.0 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY40205.1 - 0.018 14.2 0.1 1.6 7.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Thymidylate_kin PF02223.17 CBY40205.1 - 0.02 14.6 0.0 1.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_16 PF13484.6 CBY40205.1 - 0.039 14.9 1.5 0.039 14.9 1.5 2.6 1 1 1 3 3 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 CBY40205.1 - 0.055 13.5 0.1 3.7 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CBY40205.1 - 0.06 12.5 0.0 4.1 6.5 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit SbcCD_C PF13558.6 CBY40205.1 - 0.06 13.6 0.0 5.4 7.3 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 CBY40205.1 - 0.071 12.4 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 CBY40205.1 - 0.08 13.0 0.2 24 4.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CBY40205.1 - 0.2 11.9 0.3 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBY40205.1 - 0.21 11.9 0.5 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBY40205.1 - 1.3 8.9 4.2 52 3.7 0.1 3.9 2 1 2 4 4 4 0 NTPase MMR_HSR1 PF01926.23 CBY40205.1 - 1.5 8.9 3.1 18 5.5 0.1 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase Fer4_4 PF12800.7 CBY40205.1 - 3.1 8.5 14.8 0.18 12.4 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CBY40205.1 - 7.5 7.1 13.0 0.36 11.3 1.3 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY40205.1 - 9.3 6.9 12.7 0.12 13.0 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NatB_MDM20 PF09797.9 CBY40206.1 - 3.3e-35 121.7 0.3 6.1e-35 120.9 0.3 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit COG2 PF06148.11 CBY40206.1 - 0.079 13.1 1.8 0.21 11.7 0.2 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 EGF_3 PF12947.7 CBY40207.1 - 3.9e-09 36.5 60.4 6.8e-05 23.0 11.2 6.7 6 0 0 6 6 6 3 EGF domain EGF_CA PF07645.15 CBY40207.1 - 2.1e-08 34.2 70.8 3.4e-05 23.9 11.7 5.9 6 0 0 6 6 6 3 Calcium-binding EGF domain EGF PF00008.27 CBY40207.1 - 0.0034 17.7 50.8 0.022 15.0 7.4 5.6 5 0 0 5 5 5 4 EGF-like domain Ldl_recept_a PF00057.18 CBY40207.1 - 0.013 15.8 0.4 0.013 15.8 0.4 7.2 8 0 0 8 8 8 0 Low-density lipoprotein receptor domain class A hEGF PF12661.7 CBY40207.1 - 1.2 9.9 41.6 0.29 11.8 1.7 6.4 5 1 0 5 5 5 0 Human growth factor-like EGF Sushi PF00084.20 CBY40208.1 - 3e-13 50.1 39.2 1.6e-07 31.8 3.7 5.1 5 0 0 5 5 5 4 Sushi repeat (SCR repeat) CUB PF00431.20 CBY40209.1 - 2.2e-110 362.7 19.1 2.1e-23 82.7 0.0 9.4 9 0 0 9 9 9 9 CUB domain CUB_2 PF02408.20 CBY40209.1 - 0.0026 17.5 13.7 0.75 9.6 0.5 5.3 4 1 0 4 4 4 2 CUB-like domain IL12p40_C PF10420.9 CBY40209.1 - 0.19 12.2 5.8 3.7 8.1 0.2 5.2 6 0 0 6 6 6 0 Cytokine interleukin-12p40 C-terminus His_Phos_2 PF00328.22 CBY40210.1 - 1.3e-07 31.4 0.5 4.6e-05 22.9 0.1 2.6 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) Guanylate_cyc_2 PF09778.9 CBY40210.1 - 0.053 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase RIC3 PF15361.6 CBY40211.1 - 2.6e-07 31.2 0.4 2.6e-07 31.2 0.4 2.8 2 2 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 Syndecan PF01034.20 CBY40211.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain PIN_8 PF18476.1 CBY40211.1 - 0.15 11.9 13.6 0.1 12.4 12.1 1.4 1 1 0 1 1 1 0 PIN like domain CorA PF01544.18 CBY40211.1 - 0.21 10.9 4.0 0.81 8.9 4.0 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SieB PF14163.6 CBY40211.1 - 0.43 10.1 2.0 2.4 7.7 0.3 2.2 1 1 1 2 2 2 0 Super-infection exclusion protein B HrpB7 PF09486.10 CBY40211.1 - 0.7 10.3 9.5 0.26 11.7 1.3 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lipoprotein_2 PF00921.17 CBY40211.1 - 1.9 8.0 20.8 0.13 11.8 9.3 2.1 2 0 0 2 2 2 0 Borrelia lipoprotein GatB_Yqey PF02637.18 CBY40211.1 - 6.3 6.7 13.3 0.07 13.0 3.0 2.1 2 0 0 2 2 2 0 GatB domain PX PF00787.24 CBY40212.1 - 8.9e-26 90.1 0.8 4.3e-25 87.9 0.1 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CBY40212.1 - 0.00013 21.6 17.8 0.00019 21.1 15.2 2.2 2 1 0 2 2 2 1 Vps5 C terminal like RhoGEF PF00621.20 CBY40212.1 - 0.021 15.1 3.7 1 9.6 0.3 2.8 2 0 0 2 2 2 0 RhoGEF domain DUF1878 PF08963.10 CBY40212.1 - 0.04 14.4 0.3 0.14 12.6 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) DUF3452 PF11934.8 CBY40212.1 - 0.064 12.8 1.0 0.59 9.7 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF1192 PF06698.11 CBY40212.1 - 0.22 11.6 2.3 14 5.9 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) NEXCaM_BD PF16644.5 CBY40212.1 - 0.48 10.7 3.4 5.4 7.3 0.0 3.5 4 0 0 4 4 4 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Muted PF14942.6 CBY40212.1 - 0.63 10.4 12.1 0.081 13.3 4.0 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF4407 PF14362.6 CBY40212.1 - 0.92 8.8 9.4 0.46 9.8 6.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CBY40212.1 - 1.9 9.0 16.8 80 3.8 13.9 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region TBCA PF02970.16 CBY40212.1 - 7.4 7.0 10.6 1.9 8.9 4.5 3.0 2 1 1 3 3 3 0 Tubulin binding cofactor A COX15-CtaA PF02628.15 CBY40213.1 - 1.1e-95 320.5 3.0 1.2e-95 320.3 3.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.9 CBY40213.1 - 0.17 12.6 1.8 1.4 9.7 0.0 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TROVE PF05731.11 CBY40214.1 - 1.5e-66 225.3 1.9 6.7e-39 134.2 0.0 2.1 1 1 1 2 2 2 2 TROVE domain DUF5589 PF17672.1 CBY40215.1 - 0.014 15.3 1.0 0.02 14.8 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5589) RSN1_TM PF13967.6 CBY40215.1 - 0.058 13.1 0.1 0.073 12.8 0.1 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Pkinase PF00069.25 CBY40216.1 - 5.4e-34 117.7 0.0 8.2e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40216.1 - 2.8e-07 30.1 0.0 3.8e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY40216.1 - 2.9e-07 30.1 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY40216.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Trypsin PF00089.26 CBY40218.1 - 4.8e-84 281.6 19.9 7.7e-51 173.0 2.7 3.6 3 1 1 4 4 4 3 Trypsin Trypsin_2 PF13365.6 CBY40218.1 - 1.1e-14 55.6 2.1 4.1e-07 31.0 0.1 4.1 2 1 0 2 2 2 2 Trypsin-like peptidase domain Mucin PF01456.17 CBY40218.1 - 0.86 9.6 25.8 0.55 10.2 15.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY40218.1 - 1.1 9.2 18.2 0.054 13.5 6.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CBY40218.1 - 3.6 5.4 6.5 5.5 4.8 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M14 PF00246.24 CBY40219.1 - 7e-73 245.9 2.3 8.8e-73 245.6 2.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY40219.1 - 4.2e-12 46.3 0.5 9.6e-12 45.1 0.5 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide VWA PF00092.28 CBY40220.1 - 5.7e-17 62.5 0.7 1.3e-16 61.4 0.7 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY40220.1 - 1.1e-14 54.7 0.0 2.6e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY40220.1 - 6.9e-13 49.2 0.2 3.3e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.10 CBY40220.1 - 1.3e-11 44.7 0.0 5.1e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 CBY40220.1 - 1.1e-06 28.9 0.1 3.2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.14 CBY40220.1 - 0.0019 17.7 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2972 PF11186.8 CBY40220.1 - 0.0038 17.2 0.2 0.0095 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2972) CobT_C PF11775.8 CBY40220.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain EF-hand_6 PF13405.6 CBY40221.1 - 1.3e-06 27.9 0.3 5.6e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY40221.1 - 1.8e-06 27.0 0.4 1.1e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBY40221.1 - 0.00022 20.5 1.7 0.00023 20.5 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBY40221.1 - 0.0015 18.9 0.0 0.0022 18.4 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair NADHdh PF00146.21 CBY40221.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.0 1 0 0 1 1 1 0 NADH dehydrogenase Aminotran_4 PF01063.19 CBY40223.1 - 1.1e-48 166.0 0.1 1.3e-48 165.8 0.1 1.0 1 0 0 1 1 1 1 Amino-transferase class IV RPN2_C PF18004.1 CBY40225.1 - 0.044 13.7 5.8 0.094 12.6 5.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain rve PF00665.26 CBY40226.1 - 4.7e-19 68.7 0.0 8.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CBY40226.1 - 0.052 13.8 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 DDE domain DUF4794 PF16042.5 CBY40226.1 - 7.6 7.6 7.7 21 6.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4794) Cation_efflux PF01545.21 CBY40227.1 - 8.7e-48 162.7 14.3 1.3e-47 162.1 14.3 1.3 1 0 0 1 1 1 1 Cation efflux family ACBP PF00887.19 CBY40228.1 - 0.0026 18.0 0.1 0.0026 18.0 0.1 1.8 2 1 0 2 2 2 1 Acyl CoA binding protein Sec62 PF03839.16 CBY40228.1 - 0.12 11.9 8.9 0.17 11.4 8.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 CBY40228.1 - 0.5 10.2 10.0 0.62 9.8 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CBY40228.1 - 2.6 6.7 5.4 2.8 6.6 5.4 1.2 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 CBY40228.1 - 7.8 4.8 8.8 9.9 4.5 8.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ArAE_1 PF06081.11 CBY40229.1 - 0.0098 16.0 0.4 0.011 15.8 0.4 1.1 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 MAP7 PF05672.11 CBY40230.1 - 0.00014 21.6 42.6 0.00021 21.0 42.6 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DDRGK PF09756.9 CBY40230.1 - 0.048 13.2 32.2 0.054 13.1 32.2 1.1 1 0 0 1 1 1 0 DDRGK domain MAT1 PF06391.13 CBY40230.1 - 0.45 10.3 23.5 0.68 9.7 23.5 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF5401 PF17380.2 CBY40230.1 - 1.2 7.1 35.1 1.4 6.9 35.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4192 PF13830.6 CBY40230.1 - 4.4 7.3 13.0 5.6 6.9 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CAF-1_p150 PF11600.8 CBY40230.1 - 8.3 6.1 40.4 13 5.5 40.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.11 CBY40230.1 - 8.6 6.3 24.0 9.6 6.2 24.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TP53IP5 PF15331.6 CBY40230.1 - 9.8 6.3 15.3 11 6.1 15.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NAP PF00956.18 CBY40232.1 - 2.6e-07 30.1 1.2 3.5e-07 29.7 1.2 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Topoisom_bac PF01131.20 CBY40233.1 - 2.2e-103 346.5 0.0 2.8e-103 346.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 CBY40233.1 - 3.9e-19 68.5 17.0 1.1e-10 41.4 1.0 3.3 4 0 0 4 4 4 2 GRF zinc finger Toprim PF01751.22 CBY40233.1 - 4e-17 62.3 0.0 8.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 CBY40233.1 - 9.1e-05 22.2 6.3 9.1e-05 22.2 6.3 3.7 4 0 0 4 4 4 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC PF00098.23 CBY40233.1 - 0.26 11.4 4.9 1.2 9.4 4.9 2.3 1 0 0 1 1 1 0 Zinc knuckle EF-hand_1 PF00036.32 CBY40237.1 - 7.3e-20 69.0 8.6 1.2e-05 24.5 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY40237.1 - 1.1e-19 68.6 7.9 8.3e-05 22.2 1.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY40237.1 - 3.9e-17 62.5 8.8 2.9e-09 37.2 3.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY40237.1 - 6.8e-13 47.5 6.4 0.0029 17.0 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBY40237.1 - 2.6e-12 46.4 9.4 8.9e-10 38.3 1.8 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBY40237.1 - 0.02 14.8 3.8 0.15 12.0 0.1 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Prok_Ub PF14454.6 CBY40237.1 - 0.04 13.6 0.1 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic Ubiquitin EF-hand_9 PF14658.6 CBY40237.1 - 2.5 8.5 5.9 6.7 7.1 0.3 3.4 3 2 0 3 3 3 0 EF-hand domain zf-C2H2 PF00096.26 CBY40240.1 - 3.7e-16 58.6 38.7 5e-05 23.5 3.3 5.4 5 1 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40240.1 - 1.9e-15 56.2 34.1 0.00026 21.5 1.0 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY40240.1 - 5.1e-10 39.3 36.8 0.0018 18.6 0.8 5.4 5 1 0 5 5 5 3 Zinc-finger double domain zinc_ribbon_9 PF14369.6 CBY40240.1 - 1.3e-05 25.4 7.6 0.012 15.9 0.1 3.6 3 0 0 3 3 3 2 zinc-ribbon zf-C2H2_jaz PF12171.8 CBY40240.1 - 0.00022 21.4 13.1 0.47 10.8 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY40240.1 - 0.00039 20.7 12.6 0.15 12.5 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type IBR PF01485.21 CBY40240.1 - 0.0016 18.6 16.8 0.0023 18.1 4.1 2.8 1 1 2 3 3 3 1 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 CBY40240.1 - 0.0017 17.7 8.1 1.7 8.2 0.5 3.6 3 0 0 3 3 3 1 zinc-ribbon domain zf-C2H2_11 PF16622.5 CBY40240.1 - 0.005 16.6 0.6 0.005 16.6 0.6 4.1 4 1 0 4 4 3 1 zinc-finger C2H2-type HypA PF01155.19 CBY40240.1 - 0.0073 16.3 7.6 1.4 9.0 4.4 2.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_8 PF15909.5 CBY40240.1 - 0.012 15.9 12.3 0.34 11.2 5.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon TerY_C PF15616.6 CBY40240.1 - 0.014 15.5 3.3 0.092 12.9 0.8 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain PyrI_C PF02748.15 CBY40240.1 - 0.015 15.1 1.8 0.015 15.1 1.8 2.2 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HC_2 PF13913.6 CBY40240.1 - 0.019 14.8 1.9 0.019 14.8 1.9 3.7 4 0 0 4 4 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 CBY40240.1 - 0.031 14.6 22.2 0.25 11.6 1.7 3.6 1 1 4 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-3CxxC_2 PF17180.4 CBY40240.1 - 0.055 14.2 0.0 0.055 14.2 0.0 3.6 2 1 2 4 4 4 0 Zinc-binding domain zf-C2H2_6 PF13912.6 CBY40240.1 - 0.061 13.3 0.1 0.061 13.3 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger YhfH PF14149.6 CBY40240.1 - 0.15 12.1 6.5 2.1 8.4 0.4 3.1 3 0 0 3 3 3 0 YhfH-like protein zf-IS66 PF13005.7 CBY40240.1 - 0.23 11.9 10.5 15 6.1 0.1 3.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-RING_7 PF02591.15 CBY40240.1 - 0.38 11.0 7.0 21 5.4 0.1 4.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain Mu-like_Com PF10122.9 CBY40240.1 - 0.39 10.2 9.0 2.6 7.6 5.9 3.1 2 1 0 2 2 2 0 Mu-like prophage protein Com Terminase_GpA PF05876.12 CBY40240.1 - 0.41 9.1 10.6 0.039 12.5 1.4 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zf_UBZ PF18439.1 CBY40240.1 - 0.48 10.1 13.3 0.59 9.8 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 CBY40240.1 - 0.5 10.1 13.7 3.7 7.4 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 CBY40240.1 - 0.53 10.3 14.9 0.57 10.2 0.1 3.9 2 1 1 3 3 3 0 CpXC protein Elf1 PF05129.13 CBY40240.1 - 1 9.4 9.8 0.29 11.2 2.1 2.9 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 CBY40240.1 - 1.4 9.1 17.6 3.6 7.8 0.1 3.7 2 1 1 3 3 3 0 Zinc ribbon domain Cys_rich_CWC PF14375.6 CBY40240.1 - 1.5 9.3 7.3 2.5 8.6 0.2 3.2 3 0 0 3 3 3 0 Cysteine-rich CWC zf-C2H2_aberr PF17017.5 CBY40240.1 - 1.8 8.7 10.6 0.39 10.9 7.4 1.6 2 0 0 2 2 1 0 Aberrant zinc-finger ADK_lid PF05191.14 CBY40240.1 - 2.1 8.4 10.8 2.2 8.4 5.1 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid Ribosomal_S27e PF01667.17 CBY40240.1 - 2.8 7.7 8.9 8.6 6.1 0.0 3.6 3 0 0 3 3 3 0 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CBY40240.1 - 6 6.5 15.1 9.6 5.8 0.1 3.8 3 1 1 4 4 4 0 TFIIB zinc-binding Trm112p PF03966.16 CBY40240.1 - 6.6 7.4 8.4 1.5 9.4 0.9 2.9 2 1 0 2 2 2 0 Trm112p-like protein Ogr_Delta PF04606.12 CBY40240.1 - 8.1 6.5 20.0 1.4 8.9 1.5 4.3 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger XPA_N PF01286.18 CBY40240.1 - 8.7 6.5 11.1 17 5.6 0.6 3.5 3 0 0 3 3 3 0 XPA protein N-terminal fn3 PF00041.21 CBY40241.1 - 2.4e-06 27.8 0.0 6.3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain TMEM154 PF15102.6 CBY40242.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 CBY40242.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 CBY40242.1 - 0.054 13.8 0.1 0.099 12.9 0.1 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Prominin PF05478.11 CBY40242.1 - 0.065 11.2 0.0 0.079 10.9 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF3377 PF11857.8 CBY40242.1 - 0.09 12.7 1.1 0.16 11.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RAMP PF04901.13 CBY40242.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family Insulin_TMD PF17870.1 CBY40242.1 - 0.51 10.5 3.1 0.8 9.8 3.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Tub PF01167.18 CBY40243.1 - 7.7e-40 137.1 0.2 8.4e-40 137.0 0.2 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CBY40243.1 - 0.05 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Get5_bdg PF16843.5 CBY40243.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein AMP-binding PF00501.28 CBY40244.1 - 4.8e-86 289.0 0.0 5.7e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY40244.1 - 2.5e-16 60.4 0.0 7.2e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CBY40244.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain COX7C PF02935.16 CBY40245.1 - 5.7 7.3 7.2 0.86 9.9 1.5 2.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF737 PF05300.11 CBY40246.1 - 0.00025 21.5 1.8 0.00028 21.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) EGF PF00008.27 CBY40248.1 - 1.6e-06 28.3 22.7 0.00012 22.3 4.1 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 CBY40248.1 - 0.00032 21.0 41.9 0.0014 19.0 10.7 3.4 3 0 0 3 3 3 2 EGF-like domain EGF_alliinase PF04863.13 CBY40248.1 - 0.092 13.2 23.8 1.5 9.2 7.1 2.6 2 0 0 2 2 2 0 Alliinase EGF-like domain cEGF PF12662.7 CBY40248.1 - 0.13 12.2 9.9 3.3 7.7 2.6 3.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like hEGF PF12661.7 CBY40248.1 - 1.2 9.9 23.6 0.12 13.1 4.2 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF WW PF00397.26 CBY40249.1 - 5.5e-08 32.8 1.9 5.5e-08 32.8 1.9 2.1 2 0 0 2 2 2 1 WW domain PRP38_assoc PF12871.7 CBY40249.1 - 4.8 7.9 40.1 0.17 12.5 23.1 2.9 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Hepatitis_core PF00906.20 CBY40249.1 - 6.1 6.3 12.9 9.1 5.7 12.9 1.2 1 0 0 1 1 1 0 Hepatitis core antigen NARP1 PF12569.8 CBY40249.1 - 6.6 5.5 30.4 0.2 10.5 13.6 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF1509 PF07420.11 CBY40249.1 - 8.8 5.2 12.5 16 4.3 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Transformer PF06495.11 CBY40249.1 - 9.5 6.3 28.4 0.17 12.0 19.3 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein RNA_pol_Rpb2_1 PF04563.15 CBY40250.1 - 4.3e-32 111.3 0.1 6.4e-32 110.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CBY40250.1 - 5.8e-26 90.5 0.0 1.4e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CBY40250.1 - 7.2e-08 32.3 0.0 1.9e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CBY40250.1 - 5.4e-05 22.9 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 MRP-S35 PF10246.9 CBY40252.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein MRP-S35 PseudoU_synth_1 PF01416.20 CBY40253.1 - 7.2e-34 116.5 0.0 6.9e-28 97.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0240 PF06784.11 CBY40253.1 - 0.0089 16.1 1.1 0.015 15.4 1.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) YabA PF06156.13 CBY40253.1 - 1.9 9.2 5.7 4 8.1 5.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA GTP_EFTU PF00009.27 CBY40254.1 - 1.3e-61 207.6 0.0 2e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY40254.1 - 4.2e-26 90.8 0.0 9.3e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CBY40254.1 - 1.5e-24 86.0 0.0 3.1e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY40254.1 - 2.4e-18 65.9 0.0 5.8e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBY40254.1 - 2.7e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBY40254.1 - 0.00059 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBY40254.1 - 0.0011 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY40254.1 - 0.0073 15.8 0.0 0.026 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CBY40254.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 CBY40254.1 - 0.018 15.0 0.1 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Amidohydro_1 PF01979.20 CBY40254.1 - 0.025 13.9 0.1 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family SRPRB PF09439.10 CBY40254.1 - 0.11 11.9 0.0 0.61 9.5 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Endosulfine PF04667.17 CBY40255.1 - 3.1e-10 40.0 1.8 4.9e-10 39.4 1.8 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Sulfotransfer_1 PF00685.27 CBY40256.1 - 1.4e-10 41.2 1.8 1.5e-10 41.0 1.8 1.0 1 0 0 1 1 1 1 Sulfotransferase domain BAF250_C PF12031.8 CBY40256.1 - 0.0029 17.0 0.1 0.0035 16.7 0.1 1.1 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa BACK PF07707.15 CBY40256.1 - 0.05 13.7 0.6 0.065 13.3 0.6 1.2 1 0 0 1 1 1 0 BTB And C-terminal Kelch ATP-gua_Ptrans PF00217.19 CBY40257.1 - 3.1e-78 262.1 0.0 4.1e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY40257.1 - 1.3e-29 102.4 0.0 2.4e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Zona_pellucida PF00100.23 CBY40258.1 - 9.2e-34 117.4 0.2 1.1e-33 117.2 0.2 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain EGF_CA PF07645.15 CBY40259.1 - 1.9e-05 24.7 9.5 1.9e-05 24.7 9.5 6.8 7 0 0 7 7 7 4 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 CBY40259.1 - 0.066 13.5 34.3 0.53 10.6 3.6 5.8 5 0 0 5 5 5 0 Pvs28 EGF domain Pkinase PF00069.25 CBY40260.1 - 2.6e-40 138.5 0.0 3.6e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40260.1 - 5.7e-16 58.6 0.0 8.2e-16 58.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY40260.1 - 4.3e-10 39.3 0.0 7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY40260.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY40260.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY40260.1 - 0.00027 20.0 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 CBY40260.1 - 0.0057 16.3 0.2 0.015 14.9 0.2 1.6 1 1 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CBY40260.1 - 0.041 13.2 0.0 0.091 12.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBY40260.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 XendoU PF09412.10 CBY40261.1 - 7.6e-44 149.9 1.4 8.2e-44 149.8 1.4 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 CBY40261.1 - 0.00064 20.1 0.0 0.00081 19.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial EndoU nuclease Sulfotransfer_3 PF13469.6 CBY40262.1 - 0.0018 18.7 0.1 0.0087 16.5 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY40262.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase domain DUF3522 PF12036.8 CBY40263.1 - 6.7e-61 205.9 13.2 1.1e-60 205.2 13.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) TNFR_16_TM PF18422.1 CBY40263.1 - 0.11 12.5 0.3 0.34 10.9 0.3 1.8 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain AAA PF00004.29 CBY40264.1 - 1.7e-47 161.2 0.1 4.1e-42 143.7 0.0 3.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 CBY40264.1 - 4.5e-21 74.7 0.3 1.4e-20 73.1 0.3 1.9 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 CBY40264.1 - 2.2e-07 30.5 0.0 6.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY40264.1 - 2.5e-06 27.7 0.0 3.5e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Tudor-knot PF11717.8 CBY40264.1 - 3.7e-06 26.7 1.3 8.8e-06 25.5 1.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain IstB_IS21 PF01695.17 CBY40264.1 - 3.6e-05 23.6 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CBY40264.1 - 4.9e-05 23.8 0.2 0.00052 20.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CBY40264.1 - 0.0013 19.1 0.0 0.0074 16.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase PBP1_TM PF14812.6 CBY40264.1 - 0.0013 19.1 10.4 0.0013 19.1 10.4 3.6 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Parvo_NS1 PF01057.17 CBY40264.1 - 0.0018 17.4 0.0 0.081 12.0 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 CBY40264.1 - 0.0023 17.9 0.0 0.012 15.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBY40264.1 - 0.0031 17.3 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBY40264.1 - 0.0036 16.5 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBY40264.1 - 0.0039 17.5 0.9 0.15 12.4 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CBY40264.1 - 0.0072 16.9 0.1 0.081 13.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBY40264.1 - 0.0078 16.3 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 CBY40264.1 - 0.012 15.7 0.6 0.085 12.9 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CBY40264.1 - 0.022 14.9 0.4 0.21 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBY40264.1 - 0.023 14.2 0.0 0.075 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CBY40264.1 - 0.033 14.4 0.2 0.54 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CBY40264.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBY40264.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CBY40264.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBY40264.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CBY40264.1 - 0.2 11.3 0.0 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 CBY40264.1 - 1.2 8.9 0.0 1.2 8.9 0.0 3.4 3 1 0 3 3 2 0 AAA domain Methyltransf_8 PF05148.15 CBY40265.1 - 1.4e-70 237.6 2.5 1.7e-70 237.3 2.5 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBY40265.1 - 2.3e-08 34.6 0.4 1.1e-07 32.3 0.1 2.2 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CBY40265.1 - 3.7e-08 33.1 0.1 0.00029 20.4 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 CBY40265.1 - 2e-07 31.6 0.3 0.00026 21.7 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY40265.1 - 0.00012 22.0 0.0 0.00077 19.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CBY40265.1 - 0.0015 18.5 0.9 0.0063 16.5 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY40265.1 - 0.0017 18.2 0.1 0.34 10.7 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.6 CBY40265.1 - 0.0023 18.0 0.6 0.0069 16.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY40265.1 - 0.0055 16.1 0.1 0.14 11.5 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 CBY40265.1 - 0.066 11.7 0.0 5 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 CBY40265.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TED_complement PF07678.14 CBY40265.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 A-macroglobulin TED domain NAD_binding_2 PF03446.15 CBY40265.1 - 0.19 11.9 0.0 17 5.6 0.0 2.4 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase LPD5 PF18799.1 CBY40266.1 - 0.0054 17.2 1.0 0.0064 16.9 1.0 1.3 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 DUF4412 PF14371.6 CBY40266.1 - 0.018 14.9 0.2 0.022 14.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) MAP7 PF05672.11 CBY40270.1 - 0.00038 20.2 26.4 0.00038 20.2 26.4 1.5 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family PPL5 PF18168.1 CBY40270.1 - 0.066 12.5 2.9 0.072 12.4 2.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 CBY40270.1 - 0.17 10.6 3.1 0.21 10.3 3.1 1.1 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 CBY40270.1 - 0.21 11.4 4.6 0.27 11.0 4.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Asparaginase_2 PF01112.18 CBY40270.1 - 0.25 10.3 1.6 0.36 9.8 1.6 1.2 1 0 0 1 1 1 0 Asparaginase DUF913 PF06025.12 CBY40270.1 - 0.72 8.8 3.3 0.89 8.5 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 CBY40270.1 - 1 8.6 10.8 1.3 8.3 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) O-antigen_lig PF13425.6 CBY40270.1 - 1.9 7.2 2.5 2.2 7.0 2.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein eIF3_subunit PF08597.10 CBY40270.1 - 2.8 7.8 26.9 0.11 12.3 21.1 1.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PUF PF00806.19 CBY40271.1 - 6.7e-07 28.7 0.0 4.8e-05 22.8 0.0 3.9 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat DUF1400 PF07176.11 CBY40271.1 - 0.035 14.4 0.1 5.8 7.2 0.0 3.3 3 1 1 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Glyco_hydro_9 PF00759.19 CBY40273.1 - 4.7e-75 253.6 0.5 5.3e-75 253.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CD36 PF01130.21 CBY40274.1 - 4.4e-53 180.5 0.0 5.1e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 CD36 family Bromo_TP PF07524.13 CBY40276.1 - 9.5e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated EGF_CA PF07645.15 CBY40277.1 - 2e-07 31.1 21.2 2.1e-07 31.0 9.3 3.1 2 1 1 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY40277.1 - 0.00039 20.5 4.6 0.00039 20.5 4.6 2.5 2 0 0 2 2 2 1 EGF domain cEGF PF12662.7 CBY40277.1 - 0.0017 18.3 10.7 0.0076 16.2 3.0 2.9 2 0 0 2 2 2 2 Complement Clr-like EGF-like Scramblase PF03803.15 CBY40278.1 - 2.4e-11 43.4 0.1 3.8e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Scramblase Lyase_aromatic PF00221.19 CBY40280.1 - 1.7e-168 561.1 0.2 1.9e-168 560.9 0.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CMS1 PF14617.6 CBY40284.1 - 1.2e-26 93.6 12.1 6.7e-26 91.2 0.7 2.0 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit XkdW PF09636.10 CBY40284.1 - 0.061 13.4 6.1 0.12 12.4 2.0 2.4 2 0 0 2 2 2 0 XkdW protein PolyA_pol_arg_C PF12626.7 CBY40284.1 - 0.56 10.2 5.9 1.2 9.2 5.9 1.5 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus TMEM208_SND2 PF05620.11 CBY40284.1 - 2.4 7.9 4.3 3.7 7.3 4.3 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 cNMP_binding PF00027.29 CBY40285.1 - 1e-37 128.1 0.2 7e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBY40285.1 - 0.083 12.6 0.2 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Cupin domain MgtE_N PF03448.17 CBY40285.1 - 0.1 13.2 0.5 28 5.4 0.0 2.7 2 1 0 2 2 2 0 MgtE intracellular N domain MitoNEET_N PF10660.9 CBY40285.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus zf-Sec23_Sec24 PF04810.15 CBY40287.1 - 0.13 12.3 0.5 0.13 12.3 0.5 1.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF1731 PF08338.11 CBY40288.1 - 3.4e-08 33.2 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Fumble PF03630.14 CBY40289.1 - 1.3e-110 369.7 0.0 1.8e-110 369.2 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 CBY40289.1 - 2.1e-42 145.4 0.4 3.3e-42 144.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Endosulfine PF04667.17 CBY40290.1 - 3e-09 36.9 5.7 5.7e-09 36.0 5.7 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3297 PF11730.8 CBY40290.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) PH PF00169.29 CBY40291.1 - 3.6e-15 56.4 0.7 4.6e-15 56.0 0.7 1.1 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBY40291.1 - 1.2e-13 51.1 0.7 1.4e-13 50.9 0.7 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY40291.1 - 0.00016 22.1 7.0 0.00056 20.3 3.5 2.0 1 1 1 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 CBY40291.1 - 0.0078 16.5 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain EXS PF03124.14 CBY40293.1 - 1.4e-81 274.4 15.8 1.4e-81 274.4 15.8 1.4 2 0 0 2 2 2 1 EXS family DUF1295 PF06966.12 CBY40294.1 - 5.9e-53 179.8 1.9 7e-53 179.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CBY40294.1 - 0.00034 21.0 0.2 0.0021 18.4 0.0 2.4 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 CBY40294.1 - 0.001 17.9 2.2 0.0019 17.1 1.4 2.0 1 1 1 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 CBY40294.1 - 0.0018 18.3 6.8 0.0021 18.1 3.6 2.6 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CBY40294.1 - 0.002 18.5 0.7 0.0058 17.0 0.7 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 CBY40294.1 - 0.0048 16.4 0.6 0.01 15.4 0.4 1.6 1 1 0 1 1 1 1 NnrU protein BIRC6 PF12356.8 CBY40294.1 - 0.2 11.1 0.1 6.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 HAD PF12710.7 CBY40295.1 - 1.6e-08 35.2 0.0 2.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBY40295.1 - 2.2e-07 31.1 0.0 6.3e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY40295.1 - 1.2e-05 25.2 0.1 2.6e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CBY40295.1 - 0.0029 17.9 0.0 0.0066 16.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tetraspanin PF00335.20 CBY40296.1 - 0.11 12.2 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 Tetraspanin family Prismane PF03063.20 CBY40296.1 - 8.5 4.9 7.2 8.3 5.0 5.0 2.0 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family Methyltransf_25 PF13649.6 CBY40297.1 - 1.1e-12 48.5 0.1 3.3e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY40297.1 - 4.6e-12 46.0 0.2 1.1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBY40297.1 - 1.4e-11 44.4 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBY40297.1 - 3.9e-09 37.0 0.0 1.8e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY40297.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY40297.1 - 2.4e-05 25.0 0.1 6.3e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CBY40297.1 - 3e-05 23.6 0.1 4.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CBY40297.1 - 6.2e-05 23.0 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY40297.1 - 9e-05 21.5 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CBY40297.1 - 0.00014 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 CBY40297.1 - 0.0027 17.8 0.5 0.0083 16.2 0.5 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CBY40297.1 - 0.0055 16.7 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBY40297.1 - 0.007 16.1 0.2 0.018 14.8 0.1 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CBY40297.1 - 0.0086 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 CBY40297.1 - 0.028 15.4 0.0 0.049 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.16 CBY40297.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TPR_2 PF07719.17 CBY40298.1 - 4.2e-07 29.6 0.2 0.0029 17.6 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBY40298.1 - 6.1e-07 29.0 0.3 0.00064 19.4 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY40298.1 - 0.0012 19.3 0.2 0.27 11.8 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY40298.1 - 0.0052 17.5 0.1 0.12 13.2 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY40298.1 - 0.0096 16.2 0.2 7.1 7.0 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CBY40298.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBY40298.1 - 0.027 14.6 1.0 0.093 12.9 0.1 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pmp3 PF01679.17 CBY40299.1 - 0.094 12.9 0.9 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 Proteolipid membrane potential modulator TUDOR PF00567.24 CBY40300.1 - 1.4e-17 63.8 0.0 2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Aida_N PF08910.10 CBY40300.1 - 0.17 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Aida N-terminus Sulfotransfer_1 PF00685.27 CBY40302.1 - 0.0037 16.8 0.1 0.0041 16.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Ig_3 PF13927.6 CBY40304.1 - 1.3e-11 44.9 4.3 0.0016 19.0 0.2 4.2 4 0 0 4 4 4 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY40304.1 - 2.6e-11 43.4 3.0 2e-07 31.0 0.0 3.2 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain I-set PF07679.16 CBY40304.1 - 2.6e-10 40.2 3.0 3.8e-05 23.7 0.1 4.4 4 1 0 4 4 4 3 Immunoglobulin I-set domain ig PF00047.25 CBY40304.1 - 2.6e-09 37.1 6.1 0.0039 17.3 0.1 4.4 4 0 0 4 4 4 3 Immunoglobulin domain Ig_2 PF13895.6 CBY40304.1 - 2.4e-08 34.2 4.1 0.0075 16.6 0.2 4.0 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY40304.1 - 0.00021 21.4 2.0 0.017 15.3 0.1 2.9 3 0 0 3 3 3 1 Immunoglobulin V-set domain DUF1564 PF07600.11 CBY40304.1 - 0.081 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Insulin_TMD PF17870.1 CBY40305.1 - 2.4e-06 27.5 0.8 3.4e-06 27.0 0.8 1.2 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF5385 PF17359.2 CBY40305.1 - 0.0021 17.6 0.0 0.0023 17.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5385) DUF4448 PF14610.6 CBY40305.1 - 0.0026 17.6 0.0 0.0028 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 CBY40305.1 - 0.0068 16.3 0.0 0.0069 16.3 0.0 1.0 1 0 0 1 1 1 1 TMEM154 protein family SCF PF02404.15 CBY40305.1 - 0.0068 15.8 0.0 0.0068 15.8 0.0 1.0 1 0 0 1 1 1 1 Stem cell factor Chordopox_A13L PF05961.11 CBY40305.1 - 0.0069 16.6 0.0 0.0076 16.5 0.0 1.1 1 0 0 1 1 1 1 Chordopoxvirus A13L protein EphA2_TM PF14575.6 CBY40305.1 - 0.062 14.2 0.0 0.067 14.1 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FeoB_associated PF12669.7 CBY40305.1 - 0.067 13.6 3.0 0.14 12.6 3.0 1.5 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PsaL PF02605.15 CBY40305.1 - 0.1 12.2 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI DUF3377 PF11857.8 CBY40305.1 - 0.11 12.4 3.6 0.083 12.8 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2207 PF09972.9 CBY40305.1 - 0.2 10.4 0.0 0.21 10.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-RING_2 PF13639.6 CBY40306.1 - 0.0017 18.6 10.4 0.0029 17.9 10.4 1.4 1 1 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CBY40306.1 - 0.13 11.6 0.3 0.15 11.4 0.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Spc7 PF08317.11 CBY40308.1 - 0.0011 17.9 1.0 0.0011 17.9 1.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF684 PF05075.14 CBY40308.1 - 0.0016 17.5 0.3 0.0019 17.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF684) Paralemmin PF03285.15 CBY40308.1 - 0.0056 16.3 0.8 0.0061 16.2 0.8 1.0 1 0 0 1 1 1 1 Paralemmin DUF16 PF01519.16 CBY40308.1 - 0.0083 16.6 1.1 0.01 16.3 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 Fmp27_WPPW PF10359.9 CBY40308.1 - 0.013 14.4 1.7 0.014 14.3 1.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 CBY40308.1 - 0.026 14.3 3.0 0.041 13.7 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.6 CBY40308.1 - 0.031 12.9 3.0 0.036 12.7 3.0 1.0 1 0 0 1 1 1 0 AAA domain DUF3474 PF11960.8 CBY40308.1 - 0.032 14.4 0.1 0.037 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4140 PF13600.6 CBY40308.1 - 0.042 14.3 1.8 0.042 14.3 1.8 1.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TcpS PF17456.2 CBY40308.1 - 0.052 13.6 1.7 0.065 13.3 1.7 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S CENP-Q PF13094.6 CBY40308.1 - 0.053 13.7 3.1 0.059 13.6 3.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.11 CBY40308.1 - 0.086 13.2 2.3 0.19 12.2 0.8 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Snf7 PF03357.21 CBY40308.1 - 0.093 12.3 5.8 0.11 12.1 5.8 1.1 1 0 0 1 1 1 0 Snf7 HDV_ag PF01517.18 CBY40308.1 - 0.094 12.5 1.7 0.11 12.3 1.7 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Rotamase_2 PF13145.6 CBY40308.1 - 0.11 13.4 4.0 0.14 13.0 4.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain DUF3847 PF12958.7 CBY40308.1 - 0.12 12.5 5.2 0.21 11.7 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DUF1910 PF08928.10 CBY40308.1 - 0.31 11.1 5.0 0.46 10.5 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) XhlA PF10779.9 CBY40308.1 - 0.53 10.5 4.3 0.75 10.0 3.6 1.4 1 1 0 1 1 1 0 Haemolysin XhlA Tubulin PF00091.25 CBY40309.1 - 1.1e-67 228.1 0.0 1.8e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY40309.1 - 2.5e-42 144.0 0.1 4.1e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY40309.1 - 9.8e-06 25.9 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY40309.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY40309.1 - 0.034 13.3 0.0 0.089 12.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin like TrmK PF04816.12 CBY40309.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase FERM_N PF09379.10 CBY40310.1 - 3.4e-05 23.7 0.0 6.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain Ald_Xan_dh_C2 PF02738.18 CBY40311.1 - 1.1e-171 572.1 0.0 1.5e-171 571.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 CBY40311.1 - 4.9e-31 107.7 0.0 9.8e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 CBY40311.1 - 8.5e-31 105.8 0.1 2e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 CBY40311.1 - 7.4e-25 87.5 0.1 1.6e-24 86.4 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 CBY40311.1 - 5.9e-22 77.8 0.0 1.9e-21 76.1 0.0 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 CBY40311.1 - 6.6e-08 32.4 0.2 6.6e-08 32.4 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain GAS2 PF02187.17 CBY40312.1 - 2.1e-29 101.4 0.1 4.8e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 CBY40312.1 - 1.1e-10 41.6 0.2 2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain AMIN PF11741.8 CBY40313.1 - 0.061 13.5 1.8 0.9 9.7 0.2 3.0 3 1 0 3 3 3 0 AMIN domain SURF4 PF02077.15 CBY40314.1 - 6.6e-73 245.6 8.0 8e-72 242.0 8.0 1.9 1 1 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY40314.1 - 0.00013 22.4 0.2 0.00013 22.4 0.2 3.4 3 1 0 3 3 3 1 DoxX HR_lesion PF05514.11 CBY40314.1 - 0.073 13.2 11.0 0.047 13.9 2.3 2.9 2 2 0 2 2 2 0 HR-like lesion-inducing Microcin PF03526.13 CBY40314.1 - 0.52 10.2 0.1 0.52 10.2 0.1 2.0 2 1 0 2 2 2 0 Colicin E1 (microcin) immunity protein DUF2101 PF09874.9 CBY40314.1 - 1.3 8.7 10.2 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) zf-RING_2 PF13639.6 CBY40315.1 - 1.1e-10 41.7 18.7 1.4e-10 41.3 16.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBY40315.1 - 5.4e-09 36.2 12.7 5.4e-09 36.2 12.7 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY40315.1 - 7e-07 28.9 9.9 7e-07 28.9 9.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CBY40315.1 - 9e-06 25.7 7.6 1.7e-05 24.8 7.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBY40315.1 - 4.9e-05 23.1 16.1 4.9e-05 23.1 16.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY40315.1 - 0.00018 21.3 16.2 0.00018 21.3 16.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY40315.1 - 0.00042 20.2 15.1 0.00042 20.2 15.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY40315.1 - 0.00063 19.5 13.8 0.00063 19.5 13.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBY40315.1 - 0.0017 17.9 12.1 0.0017 17.9 12.1 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF4472 PF14739.6 CBY40315.1 - 0.0021 18.8 6.4 0.0021 18.8 6.4 3.0 4 0 0 4 4 2 1 Domain of unknown function (DUF4472) APG6_N PF17675.1 CBY40315.1 - 0.0023 18.5 6.5 0.0023 18.5 6.5 2.9 3 0 0 3 3 2 1 Apg6 coiled-coil region zf-RING_UBOX PF13445.6 CBY40315.1 - 0.0033 17.4 14.5 0.0033 17.4 14.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger CEP63 PF17045.5 CBY40315.1 - 0.0034 17.3 23.6 0.0071 16.3 23.6 1.5 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa TMF_TATA_bd PF12325.8 CBY40315.1 - 0.0074 16.5 22.1 0.057 13.6 2.7 3.4 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 CBY40315.1 - 0.045 13.6 12.9 0.12 12.3 3.8 2.5 2 0 0 2 2 2 0 Sec34-like family Prok-RING_4 PF14447.6 CBY40315.1 - 0.087 12.7 17.0 0.031 14.1 14.2 1.7 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 XkdW PF09636.10 CBY40315.1 - 0.13 12.4 9.6 2.6 8.2 2.1 2.7 2 0 0 2 2 2 0 XkdW protein RINGv PF12906.7 CBY40315.1 - 0.29 11.3 15.3 0.81 9.9 15.3 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CBY40315.1 - 0.38 11.0 12.4 1.5 9.0 12.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CBY40315.1 - 0.41 10.5 13.5 1 9.2 13.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Lectin_N PF03954.14 CBY40315.1 - 0.55 10.0 10.4 0.21 11.4 3.7 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF724 PF05266.14 CBY40315.1 - 0.67 9.7 21.3 0.43 10.4 10.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prok-RING_1 PF14446.6 CBY40315.1 - 0.7 9.9 14.8 2.7 8.0 14.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Seryl_tRNA_N PF02403.22 CBY40315.1 - 0.73 10.1 29.0 1.7 8.9 13.9 3.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 CBY40315.1 - 1.7 7.9 28.9 0.71 9.2 13.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TerY_C PF15616.6 CBY40315.1 - 2.7 8.1 7.6 7.9 6.6 7.6 1.7 1 0 0 1 1 1 0 TerY-C metal binding domain Baculo_IE-1 PF05290.11 CBY40315.1 - 2.8 7.9 14.0 0.18 11.8 7.8 2.1 2 1 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) Golgin_A5 PF09787.9 CBY40315.1 - 8.2 5.8 28.0 11 5.4 11.0 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 Mito_carr PF00153.27 CBY40316.1 - 5.1e-60 199.4 2.8 1e-19 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 CBY40316.1 - 0.14 12.2 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) Ribosomal_S17 PF00366.20 CBY40317.1 - 1.1e-24 86.3 0.4 1.3e-24 86.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribonuc_red_lgC PF02867.15 CBY40318.1 - 1.4e-180 601.3 0.0 1.7e-180 601.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBY40318.1 - 2.7e-22 78.5 0.0 5.4e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CBY40318.1 - 2.7e-17 63.1 0.1 1.2e-16 61.1 0.1 2.2 1 0 0 1 1 1 1 ATP cone domain ERCC4 PF02732.15 CBY40319.1 - 2.9e-14 53.6 0.0 7.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain PA28_beta PF02252.18 CBY40319.1 - 0.11 12.2 1.7 1 9.0 0.0 3.2 4 0 0 4 4 4 0 Proteasome activator pa28 beta subunit RNA_pol_Rpb6 PF01192.22 CBY40320.1 - 0.056 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb6 Cu_bind_like PF02298.17 CBY40320.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Plastocyanin-like domain Asp-B-Hydro_N PF05279.11 CBY40320.1 - 1.9 8.5 13.4 3.3 7.7 13.4 1.4 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1690 PF07956.11 CBY40320.1 - 6.9 7.1 11.6 0.65 10.4 2.6 3.0 2 1 0 3 3 3 0 Protein of Unknown function (DUF1690) zf-C3HC4_3 PF13920.6 CBY40321.1 - 0.00011 22.0 11.2 0.00011 22.0 11.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 CBY40321.1 - 0.0037 18.0 0.9 0.0037 18.0 0.9 6.6 9 1 0 9 9 9 1 C2H2-type zinc finger JmjC PF02373.22 CBY40321.1 - 0.26 11.7 1.9 0.44 11.0 0.2 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase U3_assoc_6 PF08640.11 CBY40322.1 - 0.016 15.3 1.8 0.19 11.8 2.1 2.5 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 SCAPER_N PF16501.5 CBY40322.1 - 0.027 14.5 4.5 0.032 14.2 2.6 2.1 1 1 1 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum DUF523 PF04463.12 CBY40322.1 - 0.074 13.1 1.1 0.14 12.2 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF523) DUF3510 PF12022.8 CBY40322.1 - 2.8 8.3 8.1 1.6 9.1 3.8 2.4 1 1 1 3 3 3 0 Domain of unknown function (DUF3510) CLTH PF10607.9 CBY40323.1 - 3.2e-10 40.1 1.9 4.6e-10 39.6 1.9 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CBY40323.1 - 0.00014 21.8 0.2 0.00037 20.5 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_7 PF02591.15 CBY40323.1 - 0.045 14.0 0.8 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain PyrI_C PF02748.15 CBY40323.1 - 0.079 12.9 0.8 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CSTF1_dimer PF16699.5 CBY40323.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain CTU2 PF10288.9 CBY40323.1 - 0.33 11.2 2.3 0.51 10.6 0.1 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_2 PF13639.6 CBY40323.1 - 0.36 11.2 2.3 0.49 10.8 0.4 2.2 2 0 0 2 2 2 0 Ring finger domain zf-H2C2_2 PF13465.6 CBY40323.1 - 0.87 10.1 3.1 0.84 10.2 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger double domain G-patch PF01585.23 CBY40324.1 - 1e-12 47.8 0.8 2.4e-12 46.5 0.8 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CBY40324.1 - 0.0033 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CBY40324.1 - 0.56 11.3 5.0 3.2 8.9 0.0 3.2 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein Presenilin PF01080.17 CBY40324.1 - 4.1 6.1 6.4 7 5.3 6.4 1.3 1 0 0 1 1 1 0 Presenilin Vps55 PF04133.14 CBY40326.1 - 6.8e-34 116.3 6.2 7.8e-34 116.1 6.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CFC PF09443.10 CBY40329.1 - 1.5 8.7 4.6 0.98 9.3 0.6 2.4 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Dynein_C PF18199.1 CBY40330.1 - 6e-62 209.6 0.0 9.5e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY40330.1 - 1.4e-32 112.8 1.8 2.7e-32 111.9 0.3 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBY40330.1 - 1.3e-08 34.9 0.0 7.3e-08 32.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBY40330.1 - 6.5e-07 29.0 0.1 0.00061 19.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CBY40330.1 - 3.6e-05 24.3 0.2 0.00041 20.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CBY40330.1 - 0.0014 19.1 0.1 0.0041 17.6 0.1 1.8 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CBY40330.1 - 0.0019 18.0 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBY40330.1 - 0.038 14.3 0.1 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CBY40330.1 - 0.046 14.1 0.1 0.35 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBY40330.1 - 1.3 9.5 14.3 2.7e+02 1.9 14.3 3.1 1 1 0 1 1 1 0 AAA domain Lectin_leg-like PF03388.13 CBY40331.1 - 1.8e-49 168.1 0.5 2.6e-49 167.6 0.5 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF1664 PF07889.12 CBY40331.1 - 0.89 9.6 10.2 4.2 7.4 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBY40331.1 - 7.7 6.6 9.2 1.8 8.6 1.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Histone_H2A_C PF16211.5 CBY40332.1 - 2.6e-19 68.7 1.3 3.3e-19 68.3 1.3 1.1 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY40332.1 - 3.1e-05 24.3 0.0 4.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 GLF PF03275.13 CBY40334.1 - 0.077 12.7 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 UDP-galactopyranose mutase Ldl_recept_a PF00057.18 CBY40336.1 - 3.8e-09 36.6 9.4 3.8e-09 36.6 9.4 2.9 3 1 1 4 4 4 1 Low-density lipoprotein receptor domain class A TSP_1 PF00090.19 CBY40336.1 - 5.1e-08 33.0 11.2 1.6e-07 31.4 11.2 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain Endotoxin_N PF03945.14 CBY40336.1 - 0.14 11.9 0.2 0.83 9.3 0.1 1.9 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain Tryp_inh PF17983.1 CBY40336.1 - 0.41 10.8 5.1 0.15 12.2 1.6 2.1 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Spc24 PF08286.11 CBY40336.1 - 0.48 10.7 4.8 0.63 10.3 4.3 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 PRKCSH-like PF12999.7 CBY40336.1 - 0.57 10.0 11.8 1.8 8.4 10.7 2.3 1 1 0 1 1 1 0 Glucosidase II beta subunit-like DUF16 PF01519.16 CBY40336.1 - 1.6 9.2 6.2 0.27 11.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 YabA PF06156.13 CBY40336.1 - 3.2 8.5 9.2 0.74 10.5 4.4 2.4 2 1 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBY40336.1 - 9.9 6.7 9.6 2.1 8.8 5.7 1.8 2 0 0 2 2 2 0 Cell division protein ZapB GST_C_3 PF14497.6 CBY40337.1 - 4.5e-09 36.4 0.0 6.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBY40337.1 - 0.0002 21.6 0.0 0.00041 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CBY40337.1 - 0.00073 19.7 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBY40337.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Filament PF00038.21 CBY40338.1 - 0.0021 17.7 9.5 0.0041 16.7 9.5 1.5 1 1 0 1 1 1 1 Intermediate filament protein BST2 PF16716.5 CBY40338.1 - 0.0044 17.6 1.6 0.0044 17.6 1.6 2.5 2 1 1 3 3 2 1 Bone marrow stromal antigen 2 IMD PF08397.11 CBY40338.1 - 0.006 16.0 2.2 0.0082 15.5 2.2 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain HMMR_N PF15905.5 CBY40338.1 - 0.0086 15.6 5.7 0.0086 15.6 5.7 1.5 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 CBY40338.1 - 0.028 14.2 8.0 0.041 13.6 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) EzrA PF06160.12 CBY40338.1 - 0.034 12.3 4.6 0.048 11.8 4.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 CBY40338.1 - 0.054 12.6 4.3 0.067 12.3 4.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SNAD2 PF18745.1 CBY40338.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 2 MCPsignal PF00015.21 CBY40338.1 - 0.066 13.0 1.2 1.2 8.9 0.1 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GAS PF13851.6 CBY40338.1 - 0.092 12.1 9.3 0.16 11.3 9.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CBY40338.1 - 0.1 11.9 11.8 0.05 12.9 6.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Par3_HAL_N_term PF12053.8 CBY40338.1 - 0.11 12.7 0.1 0.29 11.3 0.0 1.7 1 1 0 1 1 1 0 N-terminal of Par3 and HAL proteins HBS1_N PF08938.10 CBY40338.1 - 0.21 11.9 1.7 0.32 11.3 1.3 1.6 1 1 0 1 1 1 0 HBS1 N-terminus DUF1664 PF07889.12 CBY40338.1 - 0.23 11.5 4.8 0.25 11.4 0.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lipase_chap PF03280.14 CBY40338.1 - 0.25 11.3 13.6 0.72 9.8 4.7 2.2 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein UPF0242 PF06785.11 CBY40338.1 - 0.3 11.2 11.2 0.41 10.7 11.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 CBY40338.1 - 0.31 11.4 5.8 0.83 10.0 3.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4763 PF15960.5 CBY40338.1 - 0.44 9.8 11.3 1.9 7.7 11.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Uds1 PF15456.6 CBY40338.1 - 0.46 10.7 8.4 0.11 12.6 5.1 1.7 2 0 0 2 2 1 0 Up-regulated During Septation V-SNARE PF05008.15 CBY40338.1 - 1 9.8 7.7 0.7 10.3 4.9 2.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 CBY40338.1 - 1.4 7.7 13.1 0.18 10.6 8.7 1.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 CBY40338.1 - 1.5 9.3 13.6 0.28 11.6 2.0 2.2 1 1 1 2 2 2 0 Fez1 APG6_N PF17675.1 CBY40338.1 - 2 9.0 10.9 0.18 12.3 1.2 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region Fungal_TACC PF12709.7 CBY40338.1 - 2.1 8.8 7.4 5.1 7.6 0.9 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMPIT PF07851.13 CBY40338.1 - 2.4 7.3 6.5 8.9 5.4 1.1 2.0 1 1 0 2 2 2 0 TMPIT-like protein DUF5624 PF18538.1 CBY40338.1 - 2.8 8.0 5.3 24 5.0 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5624) Sec8_exocyst PF04048.14 CBY40338.1 - 2.9 7.8 7.0 27 4.7 7.0 2.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain CENP-H PF05837.12 CBY40338.1 - 5.9 7.3 11.2 0.2 12.1 3.4 2.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) FUSC PF04632.12 CBY40338.1 - 6.2 5.2 6.2 7.3 5.0 6.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 CBY40338.1 - 6.8 6.7 12.6 1.3 9.1 8.0 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FadA PF09403.10 CBY40338.1 - 6.9 7.2 12.4 1.5 9.4 1.3 2.6 3 0 0 3 3 3 0 Adhesion protein FadA Kelch_2 PF07646.15 CBY40340.1 - 0.031 14.2 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.15 CBY40341.1 - 0.037 14.0 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Trypsin PF00089.26 CBY40342.1 - 9.7e-39 133.4 0.0 1.3e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY40342.1 - 2.6e-06 27.8 0.0 7.5e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY40342.1 - 0.042 14.8 0.0 0.099 13.5 0.0 1.8 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF316 PF03761.15 CBY40342.1 - 0.095 12.3 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Rab5ip PF07019.12 CBY40343.1 - 1.5e-16 60.7 13.1 1.9e-16 60.4 13.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) UCH PF00443.29 CBY40344.1 - 1.2e-35 123.3 0.0 1.7e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY40344.1 - 2.8e-12 46.9 0.5 1.7e-10 41.0 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CBY40344.1 - 2.2e-06 27.3 0.0 5.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 CBY40344.1 - 0.00029 20.4 0.2 0.027 14.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Syja_N PF02383.18 CBY40345.1 - 4.9e-84 282.4 3.8 4.9e-84 282.4 3.8 1.5 2 0 0 2 2 2 1 SacI homology domain Striatin PF08232.12 CBY40347.1 - 0.59 10.7 5.8 1.1 9.8 5.8 1.4 1 0 0 1 1 1 0 Striatin family Cyclin_N PF00134.23 CBY40348.1 - 1.1e-42 144.8 0.8 2.1e-42 143.8 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY40348.1 - 1.3e-24 86.6 0.2 3.5e-24 85.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Rpn9_C PF18261.1 CBY40348.1 - 0.047 13.3 0.1 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Rpn9 C-terminal helix CLPTM1 PF05602.12 CBY40349.1 - 2.9e-87 293.5 0.1 5.4e-87 292.6 0.1 1.4 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Proteasome PF00227.26 CBY40350.1 - 8.1e-48 162.4 0.3 9.7e-48 162.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit RsfS PF02410.15 CBY40351.1 - 3.9e-19 68.9 0.0 1.2e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation BTB PF00651.31 CBY40352.1 - 2e-29 102.1 2.2 3.6e-29 101.2 0.5 2.1 1 1 1 2 2 2 1 BTB/POZ domain MATH PF00917.26 CBY40352.1 - 3.7e-07 30.3 0.7 1.2e-06 28.7 0.4 2.0 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 CBY40352.1 - 0.0013 18.8 0.5 0.2 11.8 0.0 3.6 3 1 1 4 4 4 1 BTB And C-terminal Kelch Prefoldin_2 PF01920.20 CBY40353.1 - 2.4e-17 62.8 0.6 2.5e-17 62.7 0.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Pkinase PF00069.25 CBY40355.1 - 3.4e-14 52.8 0.1 6.4e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40355.1 - 1.8e-06 27.5 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase TSP_1 PF00090.19 CBY40356.1 - 0.00023 21.3 4.9 0.00023 21.3 4.9 5.4 5 0 0 5 5 5 2 Thrombospondin type 1 domain Zona_pellucida PF00100.23 CBY40357.1 - 1.2e-28 100.6 0.1 1.5e-28 100.3 0.1 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain FXR_C1 PF16096.5 CBY40357.1 - 0.051 13.8 3.7 0.17 12.1 0.4 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Lectin_C PF00059.21 CBY40358.1 - 2.8e-10 40.9 3.1 0.00039 21.1 0.0 2.2 2 0 0 2 2 2 2 Lectin C-type domain Lectin_C PF00059.21 CBY40360.1 - 7.5e-17 62.0 10.5 3.4e-12 47.1 0.9 2.3 2 0 0 2 2 2 2 Lectin C-type domain Fibrinogen_C PF00147.18 CBY40361.1 - 6e-06 26.2 0.1 8e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Anoctamin PF04547.12 CBY40362.1 - 3.5e-49 167.9 12.4 1.4e-29 103.3 0.1 2.0 1 1 1 2 2 2 2 Calcium-activated chloride channel RSN1_7TM PF02714.15 CBY40362.1 - 0.00021 20.7 0.3 0.00038 19.8 0.3 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF3021 PF11457.8 CBY40362.1 - 0.0026 18.1 2.6 0.0026 18.1 2.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3021) Pkinase PF00069.25 CBY40364.1 - 9.7e-20 71.0 0.4 1.3e-19 70.6 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Zona_pellucida PF00100.23 CBY40364.1 - 1.9e-14 54.1 0.0 3.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Zona pellucida-like domain Pkinase_Tyr PF07714.17 CBY40364.1 - 6.1e-07 29.0 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY40364.1 - 9.1e-06 25.2 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY40364.1 - 0.0018 17.9 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY40364.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBY40364.1 - 0.039 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CBY40364.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase UPF0561 PF10573.9 CBY40365.1 - 0.043 13.9 1.3 0.087 13.0 1.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 HemN_C PF06969.16 CBY40365.1 - 0.073 13.1 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 0 HemN C-terminal domain Metallophos PF00149.28 CBY40366.1 - 2.6e-15 57.5 3.8 3.8e-15 56.9 3.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyto_heme_lyase PF01265.17 CBY40368.1 - 6.8e-55 186.7 8.3 5.5e-54 183.7 8.3 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PAXNEB PF05625.11 CBY40369.1 - 1.4e-12 47.5 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Piwi PF02171.17 CBY40370.1 - 2.7e-80 269.8 0.0 4.2e-80 269.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CBY40370.1 - 1.1e-16 61.7 0.5 2.2e-16 60.7 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CBY40370.1 - 3e-16 58.8 0.4 2.4e-15 55.9 0.0 2.5 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 CBY40370.1 - 1.9e-13 50.4 0.5 1.3e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 CBY40370.1 - 8e-07 29.2 0.1 2.3e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CBY40370.1 - 0.00092 19.5 0.0 0.0027 18.0 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain THF_DHG_CYH PF00763.23 CBY40370.1 - 0.14 12.4 0.0 0.88 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Rad60-SLD PF11976.8 CBY40371.1 - 1.7e-09 37.3 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBY40371.1 - 1.8e-05 24.4 0.6 5.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family ATG16 PF08614.11 CBY40371.1 - 0.00062 20.0 4.6 0.00062 20.0 4.6 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-H PF05837.12 CBY40371.1 - 0.029 14.8 7.3 0.059 13.8 7.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF1663 PF07909.11 CBY40371.1 - 0.19 10.5 2.1 0.27 9.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) Peptidase_C57 PF03290.13 CBY40371.1 - 2.7 6.6 6.0 0.33 9.6 1.5 1.7 3 0 0 3 3 3 0 Vaccinia virus I7 processing peptidase ABC_tran PF00005.27 CBY40372.1 - 4.6e-11 43.4 0.0 7.8e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY40372.1 - 5.5e-07 29.7 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBY40372.1 - 0.00035 20.1 0.0 0.00043 19.8 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain TIR-like PF10137.9 CBY40372.1 - 0.015 15.3 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain Cmyb_C PF09316.10 CBY40374.1 - 1.3e-10 41.2 0.2 9.1e-10 38.5 0.0 2.5 2 0 0 2 2 2 1 C-myb, C-terminal DUF3704 PF12488.8 CBY40374.1 - 0.21 11.3 1.9 0.29 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Myb_DNA-binding PF00249.31 CBY40375.1 - 1.8e-38 130.5 14.9 7.1e-18 64.5 1.5 3.7 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY40375.1 - 1.2e-30 105.5 14.6 9.8e-16 57.8 1.7 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CBY40375.1 - 0.0014 18.5 1.7 0.0074 16.2 0.3 2.4 1 1 2 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 CBY40375.1 - 0.013 15.5 0.2 1.1 9.3 0.0 3.1 2 2 1 3 3 3 0 SLIDE Myb_DNA-bind_4 PF13837.6 CBY40375.1 - 0.082 13.3 7.2 5.5 7.4 0.1 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 CBY40375.1 - 0.8 9.8 4.4 8.6 6.5 4.4 2.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ABC2_membrane PF01061.24 CBY40376.1 - 1.7e-39 135.4 26.3 2.2e-39 135.0 26.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBY40376.1 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CBY40376.1 - 4.8e-05 23.3 0.1 8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CBY40376.1 - 0.00019 21.4 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CBY40376.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBY40376.1 - 0.021 14.9 0.7 0.045 13.8 0.7 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CBY40376.1 - 0.021 14.5 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CBY40376.1 - 0.025 15.1 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CBY40376.1 - 0.033 13.6 0.2 0.19 11.1 0.2 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CBY40376.1 - 0.078 13.1 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Dynamin_N PF00350.23 CBY40376.1 - 0.095 12.7 1.4 0.3 11.1 0.6 2.2 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 CBY40376.1 - 0.14 12.5 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 CBY40376.1 - 8 5.6 9.0 1.8 7.8 5.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Chibby PF14645.6 CBY40378.1 - 5.4e-23 81.6 2.0 6.6e-23 81.3 2.0 1.1 1 0 0 1 1 1 1 Chibby family ApoB100_C PF12491.8 CBY40379.1 - 0.061 13.3 0.5 2.2 8.3 0.1 3.4 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal FhuF PF06276.12 CBY40379.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Ferric iron reductase FhuF-like transporter DUF5598 PF18127.1 CBY40383.1 - 5.2e-35 119.8 0.8 6.3e-33 113.1 0.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5598) zf-H2C2_2 PF13465.6 CBY40384.1 - 6.4e-23 80.1 28.6 1.1e-07 32.0 2.9 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CBY40384.1 - 9.3e-21 73.1 26.5 2e-06 27.9 3.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40384.1 - 5.6e-18 64.1 25.0 0.00028 21.4 2.2 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY40384.1 - 2.3e-10 40.5 13.5 0.0025 18.0 0.1 4.3 4 0 0 4 4 4 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY40384.1 - 3.1e-09 36.6 20.5 0.00072 19.5 2.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY40384.1 - 8.1e-08 32.4 14.1 1.4e-06 28.5 3.9 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CBY40384.1 - 5.9e-07 29.7 19.5 0.0012 19.1 0.8 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.15 CBY40384.1 - 1.1e-06 28.5 14.1 0.0019 18.2 3.1 3.4 2 1 2 4 4 4 2 BED zinc finger GAGA PF09237.11 CBY40384.1 - 5.8e-05 22.8 8.8 0.45 10.4 0.2 4.0 1 1 3 4 4 4 2 GAGA factor zf-C2H2_2 PF12756.7 CBY40384.1 - 0.00045 20.5 16.5 0.38 11.1 0.9 4.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) Zn-C2H2_12 PF18112.1 CBY40384.1 - 0.00077 19.9 10.5 1.6 9.3 0.5 4.5 4 0 0 4 4 4 1 Autophagy receptor zinc finger-C2H2 domain zinc_ribbon_15 PF17032.5 CBY40384.1 - 0.00088 20.0 5.5 0.36 11.6 1.2 2.3 1 1 0 2 2 2 2 zinc-ribbon family Prok-RING_1 PF14446.6 CBY40384.1 - 0.0013 18.6 8.9 1.8 8.6 0.1 4.2 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CBY40384.1 - 0.0031 17.6 12.4 1.1 9.4 1.6 4.0 1 1 3 4 4 4 2 KIAA1045 RING finger Zn-ribbon_8 PF09723.10 CBY40384.1 - 0.01 15.9 11.2 0.035 14.2 1.5 3.5 2 1 2 4 4 4 0 Zinc ribbon domain BolA PF01722.18 CBY40384.1 - 0.012 15.8 4.4 7 7.0 0.9 3.2 2 1 1 3 3 3 0 BolA-like protein zf-CHCC PF10276.9 CBY40384.1 - 0.016 15.2 5.3 2.1 8.4 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger domain HypA PF01155.19 CBY40384.1 - 0.019 15.0 5.7 0.35 10.9 0.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 CBY40384.1 - 0.027 14.4 11.1 0.17 11.8 1.8 3.1 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_9 PF16293.5 CBY40384.1 - 0.029 14.2 7.9 3.4 7.6 0.1 3.6 3 1 1 4 4 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 CBY40384.1 - 0.04 14.2 11.9 0.77 10.1 0.6 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 CBY40384.1 - 0.071 13.8 11.7 0.82 10.3 1.6 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-AN1 PF01428.16 CBY40384.1 - 0.1 12.8 17.1 1.6 9.0 0.9 4.2 3 1 1 4 4 4 0 AN1-like Zinc finger zf-H2C2_5 PF13909.6 CBY40384.1 - 0.13 12.0 26.0 0.39 10.5 1.7 5.1 4 2 0 4 4 4 0 C2H2-type zinc-finger domain Cys_rich_CPXG PF14255.6 CBY40384.1 - 0.14 12.1 4.1 1.4 8.9 0.5 3.4 3 1 0 3 3 3 0 Cysteine-rich CPXCG FYVE PF01363.21 CBY40384.1 - 0.22 11.7 15.6 1.1 9.4 9.9 2.9 1 1 2 3 3 3 0 FYVE zinc finger Elf1 PF05129.13 CBY40384.1 - 0.54 10.3 14.5 0.7 10.0 2.8 3.6 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-MYST PF17772.1 CBY40384.1 - 1 9.1 9.7 16 5.2 0.1 4.0 4 0 0 4 4 4 0 MYST family zinc finger domain HNH_5 PF14279.6 CBY40384.1 - 1.1 9.1 8.8 8.6 6.3 0.4 3.8 3 1 0 3 3 3 0 HNH endonuclease zf-MYND PF01753.18 CBY40384.1 - 1.9 8.7 9.2 40 4.4 5.5 3.2 1 1 1 2 2 2 0 MYND finger C1_4 PF07975.12 CBY40384.1 - 2 8.7 12.8 12 6.2 1.7 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain zf-met2 PF12907.7 CBY40384.1 - 2.6 8.3 11.0 11 6.3 0.9 3.7 3 0 0 3 3 3 0 Zinc-binding FYDLN_acid PF09538.10 CBY40384.1 - 3 8.6 5.3 29 5.4 3.0 2.9 2 1 0 2 2 1 0 Protein of unknown function (FYDLN_acid) LIM PF00412.22 CBY40384.1 - 3.7 7.8 13.7 16 5.8 0.4 3.6 1 1 2 4 4 4 0 LIM domain DUF2256 PF10013.9 CBY40384.1 - 4.5 7.5 10.9 25 5.1 0.2 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_ZIC PF18366.1 CBY40384.1 - 4.7 7.4 13.1 0.33 11.1 0.6 3.5 2 1 2 4 4 4 0 Zic proteins zinc finger domain Zn_Tnp_IS1595 PF12760.7 CBY40384.1 - 5.2 7.1 13.3 34 4.5 0.0 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 CBY40384.1 - 6 7.2 7.4 1.6 9.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-C2H2_11 PF16622.5 CBY40384.1 - 7.4 6.4 0.0 7.4 6.4 0.0 4.2 5 0 0 5 5 4 0 zinc-finger C2H2-type VWA PF00092.28 CBY40385.1 - 0.11 12.7 0.1 0.34 11.1 0.0 1.8 2 1 0 2 2 2 0 von Willebrand factor type A domain ATG16 PF08614.11 CBY40387.1 - 0.00099 19.4 0.4 0.00099 19.4 0.4 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 CBY40387.1 - 0.013 14.6 2.0 0.022 13.9 2.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBY40387.1 - 0.033 13.6 0.3 0.039 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CBY40387.1 - 0.035 13.4 0.6 0.035 13.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 CBY40387.1 - 0.099 13.2 3.6 2.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 GIT_CC PF16559.5 CBY40387.1 - 0.14 12.1 3.9 0.22 11.4 1.1 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor PRKG1_interact PF15898.5 CBY40387.1 - 0.23 12.4 7.1 0.1 13.5 4.3 1.9 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 CBY40387.1 - 0.24 10.7 7.1 1.4 8.3 7.2 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding E2F_CC-MB PF16421.5 CBY40387.1 - 0.25 11.7 3.8 0.6 10.5 0.6 2.5 2 2 0 2 2 2 0 E2F transcription factor CC-MB domain Prefoldin_2 PF01920.20 CBY40387.1 - 0.31 11.0 0.2 0.31 11.0 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit Rho_Binding PF08912.11 CBY40387.1 - 0.39 11.6 5.0 0.18 12.6 0.9 2.3 2 0 0 2 2 2 0 Rho Binding YabA PF06156.13 CBY40387.1 - 0.41 11.3 2.7 0.98 10.1 2.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Ax_dynein_light PF10211.9 CBY40387.1 - 0.55 10.2 6.4 0.67 9.9 1.1 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain KLRAQ PF10205.9 CBY40387.1 - 0.76 10.1 5.5 1.5 9.1 2.9 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein APG6_N PF17675.1 CBY40387.1 - 0.87 10.1 5.8 0.73 10.4 0.3 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region JAKMIP_CC3 PF16034.5 CBY40387.1 - 1.3 8.9 7.7 0.6 10.0 0.8 2.7 2 1 1 3 3 3 0 JAKMIP CC3 domain ZapB PF06005.12 CBY40387.1 - 1.7 9.1 6.8 12 6.4 6.8 2.3 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_Maf PF03131.17 CBY40387.1 - 2.6 8.6 8.2 21 5.7 1.0 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor DivIC PF04977.15 CBY40387.1 - 3.3 7.6 8.9 0.67 9.8 1.8 3.0 1 1 1 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 CBY40387.1 - 5.9 7.1 10.6 0.57 10.4 1.0 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Phospholip_A2_1 PF00068.19 CBY40389.1 - 1e-09 38.9 6.7 1.3e-09 38.5 6.7 1.2 1 0 0 1 1 1 1 Phospholipase A2 DUF4710 PF15828.5 CBY40389.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4710) Sec15 PF04091.12 CBY40390.1 - 0.32 10.4 0.4 0.38 10.1 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like FR47 PF08445.10 CBY40391.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 CBY40392.1 - 2.7e-22 79.4 0.0 5.9e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40392.1 - 1.1e-06 28.2 0.0 6.1e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase PKcGMP_CC PF16808.5 CBY40392.1 - 1.2 9.1 6.2 3.2 7.7 6.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sigma_reg_N PF13800.6 CBY40393.1 - 0.0032 17.7 1.9 0.16 12.3 0.0 3.5 3 0 0 3 3 3 1 Sigma factor regulator N-terminal Methyltrans_RNA PF04452.14 CBY40393.1 - 0.063 12.6 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 RNA methyltransferase Ion_trans PF00520.31 CBY40394.1 - 1.1e-09 37.9 8.8 7.8e-09 35.1 8.8 2.1 1 1 0 1 1 1 1 Ion transport protein DUF4349 PF14257.6 CBY40394.1 - 0.12 11.8 5.3 4 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) PKD_channel PF08016.12 CBY40394.1 - 0.25 10.0 8.8 0.55 8.9 0.5 2.2 2 0 0 2 2 2 0 Polycystin cation channel RseC_MucC PF04246.12 CBY40394.1 - 1.2 9.1 5.2 5.3 7.0 3.5 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.9 CBY40394.1 - 1.5 7.5 7.7 2.3 6.9 3.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Trefoil PF00088.18 CBY40395.1 - 2e-21 75.6 25.9 2e-10 40.4 5.4 3.5 3 0 0 3 3 3 3 Trefoil (P-type) domain BSD PF03909.17 CBY40396.1 - 1.3e-11 44.3 1.1 3.2e-11 43.1 1.1 1.7 1 0 0 1 1 1 1 BSD domain zf-C2H2 PF00096.26 CBY40397.1 - 8.1e-14 51.2 52.6 0.0026 18.1 3.3 7.7 8 0 0 8 8 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40397.1 - 2.1e-13 49.9 52.7 0.0011 19.6 3.2 8.1 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY40397.1 - 1.3e-05 25.4 2.3 1.3e-05 25.4 2.3 9.9 9 1 1 10 10 10 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 CBY40397.1 - 0.0019 18.5 27.6 0.2 12.0 0.1 6.3 6 1 0 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CBY40397.1 - 0.0043 17.7 25.2 0.0047 17.6 0.2 6.2 4 2 2 6 6 6 2 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 CBY40397.1 - 0.016 15.7 23.0 0.46 11.0 0.8 6.5 5 1 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 CBY40397.1 - 0.022 14.7 1.2 0.022 14.7 1.2 6.2 8 0 0 8 8 7 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 CBY40397.1 - 0.049 13.7 42.7 0.13 12.3 1.8 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger Fructosamin_kin PF03881.14 CBY40397.1 - 0.061 12.5 0.3 0.17 11.1 0.3 1.6 1 1 1 2 2 2 0 Fructosamine kinase zf-C2H2_jaz PF12171.8 CBY40397.1 - 0.067 13.5 24.7 0.43 10.9 0.3 6.3 7 0 0 7 7 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CBY40397.1 - 0.13 12.0 29.8 0.28 11.0 0.0 5.6 6 0 0 6 6 5 0 zinc-finger C2H2-type DUF629 PF04780.12 CBY40397.1 - 0.29 9.6 13.1 0.14 10.7 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF629) zf-met PF12874.7 CBY40397.1 - 0.68 10.4 25.1 0.16 12.4 0.3 6.7 6 1 1 7 7 7 0 Zinc-finger of C2H2 type DZR PF12773.7 CBY40397.1 - 2.1 8.4 23.6 17 5.5 0.4 5.2 4 1 0 4 4 4 0 Double zinc ribbon DUF3268 PF11672.8 CBY40397.1 - 4.4 7.7 8.6 10 6.5 0.6 3.4 3 0 0 3 3 3 0 zinc-finger-containing domain zf-Di19 PF05605.12 CBY40397.1 - 6.6 7.1 30.3 1.4 9.3 1.1 5.0 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF1178 PF06676.11 CBY40397.1 - 6.8 7.1 13.2 0.22 11.9 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) DHR-2 PF06920.13 CBY40398.1 - 6.3e-41 140.6 0.2 1.3e-40 139.6 0.2 1.6 1 1 0 1 1 1 1 Dock homology region 2 Birna_VP5 PF03042.14 CBY40398.1 - 0.095 12.7 0.6 0.25 11.4 0.1 1.9 2 0 0 2 2 2 0 Birnavirus VP5 protein ParcG PF10274.9 CBY40398.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Parkin co-regulated protein DUF4783 PF16022.5 CBY40400.1 - 0.048 13.8 0.8 0.059 13.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) PseudoU_synth_1 PF01416.20 CBY40401.1 - 7.2e-11 42.5 0.0 3e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase TPR_2 PF07719.17 CBY40402.1 - 8.7e-07 28.6 24.3 0.49 10.6 0.3 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY40402.1 - 0.064 14.1 4.4 0.65 11.0 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2200 PF09966.9 CBY40402.1 - 0.074 13.2 0.0 0.48 10.6 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) TPR_16 PF13432.6 CBY40402.1 - 0.16 12.7 7.1 3.8 8.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBY40402.1 - 0.83 10.2 2.9 3.5 8.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBY40402.1 - 1.8 9.1 8.2 1.6 9.3 1.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB PF00651.31 CBY40403.1 - 1.5e-10 41.2 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Polysacc_synt_4 PF04669.13 CBY40404.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis RRXRR PF14239.6 CBY40405.1 - 1.4 8.8 15.1 1.8 8.4 15.1 1.2 1 0 0 1 1 1 0 RRXRR protein DDRGK PF09756.9 CBY40405.1 - 2.9 7.4 17.3 3.4 7.2 17.3 1.1 1 0 0 1 1 1 0 DDRGK domain Pkinase PF00069.25 CBY40406.1 - 1.6e-30 106.4 0.0 3.7e-30 105.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain C1_1 PF00130.22 CBY40406.1 - 1.1e-22 79.6 17.1 8.6e-16 57.6 4.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 CBY40406.1 - 4e-08 32.9 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBY40406.1 - 0.0059 16.7 7.0 0.13 12.4 0.7 2.6 2 0 0 2 2 2 2 FYVE zinc finger FYVE_2 PF02318.16 CBY40406.1 - 0.0086 16.3 9.6 0.014 15.6 1.9 2.5 2 0 0 2 2 2 1 FYVE-type zinc finger Kinase-like PF14531.6 CBY40406.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like C1_2 PF03107.16 CBY40406.1 - 0.051 13.9 14.6 0.5 10.7 3.4 2.5 2 0 0 2 2 2 0 C1 domain Med27 PF11571.8 CBY40406.1 - 0.94 9.9 0.0 0.94 9.9 0.0 3.5 3 1 0 3 3 3 0 Mediator complex subunit 27 HypA PF01155.19 CBY40406.1 - 3.2 7.8 7.8 4 7.5 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0167 PF03691.14 CBY40406.1 - 5.1 6.9 8.5 0.16 11.7 0.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Zf_RING PF16744.5 CBY40406.1 - 8.5 6.6 11.5 0.3 11.2 1.5 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger EGF_CA PF07645.15 CBY40408.1 - 7.5e-157 509.4 444.3 1e-08 35.2 8.3 28.5 26 2 2 28 28 28 27 Calcium-binding EGF domain EGF_3 PF12947.7 CBY40408.1 - 9.8e-87 284.8 376.5 1.5e-08 34.7 11.7 29.3 23 5 5 28 28 28 24 EGF domain cEGF PF12662.7 CBY40408.1 - 8.8e-57 188.6 256.3 2.2e-07 30.7 0.3 27.5 26 1 0 26 26 26 19 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY40408.1 - 1.5e-16 60.4 372.9 0.0053 17.0 3.7 27.2 22 4 4 26 26 26 20 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY40408.1 - 6.8e-16 58.0 316.2 4.7e-05 23.3 2.4 26.3 24 3 2 26 26 26 13 MSP1 EGF domain 1 EGF PF00008.27 CBY40408.1 - 1.3e-14 54.2 370.2 0.012 15.9 5.8 28.2 26 3 2 28 28 28 19 EGF-like domain hEGF PF12661.7 CBY40408.1 - 5.2e-09 36.4 324.3 0.00016 22.2 5.4 30.8 30 1 0 30 30 30 14 Human growth factor-like EGF ITI_HC_C PF06668.12 CBY40408.1 - 7.3e-06 25.8 0.1 1.1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus Plasmod_Pvs28 PF06247.11 CBY40408.1 - 0.0092 16.3 5.4 0.0092 16.3 5.4 26.0 21 4 3 24 24 24 11 Pvs28 EGF domain UBX PF00789.20 CBY40409.1 - 4e-16 59.0 0.0 5.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 UBX domain Pkinase PF00069.25 CBY40410.1 - 5.1e-44 150.6 0.9 1.6e-43 149.0 0.9 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40410.1 - 1.7e-20 73.4 0.2 6.4e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBY40410.1 - 0.0004 19.5 0.8 0.0014 17.6 0.1 2.0 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBY40410.1 - 0.58 9.7 0.0 0.58 9.7 0.0 3.8 3 1 1 4 4 4 0 RIO1 family GST_N PF02798.20 CBY40411.1 - 1.1e-16 60.9 0.1 2.5e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY40411.1 - 7.4e-16 58.3 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY40411.1 - 4.1e-10 39.8 0.0 6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-NOSIP PF15906.5 CBY40411.1 - 0.071 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Neur_chan_memb PF02932.16 CBY40413.1 - 1.5e-34 120.2 10.0 3.3e-32 112.4 10.0 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY40413.1 - 4.1e-26 91.8 0.6 6.5e-26 91.1 0.6 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain zf-LITAF-like PF10601.9 CBY40414.1 - 1.3 9.3 10.6 0.43 10.9 2.0 3.7 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Trypsin PF00089.26 CBY40415.1 - 8.8e-47 159.7 1.0 9e-47 159.7 0.4 1.3 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 CBY40415.1 - 2.1e-06 28.7 0.0 4.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY40415.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) COX17 PF05051.13 CBY40418.1 - 3e-20 72.3 5.7 3.6e-20 72.0 5.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Helicase_C PF00271.31 CBY40419.1 - 2.4e-17 63.3 0.0 3.4e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CBY40419.1 - 4.9e-16 59.0 0.0 8.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CBY40419.1 - 6.7e-10 39.5 1.9 1.8e-09 38.1 1.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding AAA_34 PF13872.6 CBY40419.1 - 0.0071 15.3 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Arg_decarbox_C PF17944.1 CBY40419.1 - 0.39 11.3 1.2 2.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Frag1 PF10277.9 CBY40424.1 - 6.2e-10 39.0 16.6 7.3e-10 38.7 16.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tnp_zf-ribbon_2 PF13842.6 CBY40425.1 - 0.01 16.6 0.5 0.022 15.6 0.5 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DZF PF07528.14 CBY40426.1 - 1.2e-50 172.5 0.1 1.6e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 DZF domain AAA_32 PF13654.6 CBY40426.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Gly-rich_Ago1 PF12764.7 CBY40426.1 - 0.63 10.8 6.2 1.7 9.5 6.2 1.7 1 0 0 1 1 1 0 Glycine-rich region of argonaut TSP_1 PF00090.19 CBY40428.1 - 7.2e-05 22.9 5.0 7.2e-05 22.9 5.0 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain CHGN PF05679.16 CBY40429.1 - 3.1e-95 320.0 4.1 3.7e-95 319.7 4.1 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Glyco_transf_7C PF02709.14 CBY40429.1 - 9.8e-10 38.0 0.5 2.3e-09 36.7 0.5 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY40429.1 - 5.4e-05 22.8 0.2 0.0018 17.8 0.2 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF4618 PF15397.6 CBY40429.1 - 0.0099 15.3 0.3 0.021 14.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) MRP_L53 PF10780.9 CBY40429.1 - 0.011 15.9 0.0 0.1 12.8 0.0 2.3 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Fringe PF02434.16 CBY40429.1 - 0.045 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Biopterin_H PF00351.21 CBY40430.1 - 5.6e-38 130.8 0.1 6.5e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase EF-hand_1 PF00036.32 CBY40431.1 - 7e-12 44.0 3.6 1.2e-05 24.6 1.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY40431.1 - 8.2e-12 45.4 0.9 2.4e-11 43.9 0.9 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY40431.1 - 9.4e-11 40.8 2.4 3.5e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY40431.1 - 9e-07 28.1 3.9 0.014 14.9 0.6 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY40431.1 - 9.1e-07 28.6 4.6 1.3e-06 28.1 3.2 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 CBY40431.1 - 0.00075 19.8 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain GAGE PF05831.11 CBY40431.1 - 0.0043 17.6 0.8 0.0085 16.6 0.8 1.4 1 0 0 1 1 1 1 GAGE protein EF-hand_14 PF17959.1 CBY40431.1 - 0.068 13.5 0.1 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 CBY40431.1 - 0.12 12.3 0.1 0.39 10.7 0.2 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SepRS_C PF18006.1 CBY40433.1 - 0.17 12.0 1.0 0.5 10.5 0.1 2.1 2 0 0 2 2 2 0 O-phosphoseryl-tRNA synthetase C-terminal domain ABC_tran PF00005.27 CBY40434.1 - 1.3e-28 100.3 0.0 2.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBY40434.1 - 8e-16 58.1 17.1 8e-16 58.1 17.1 2.5 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 CBY40434.1 - 1.2e-08 35.1 0.0 1.5e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY40434.1 - 0.0036 17.8 0.0 0.0079 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CBY40434.1 - 0.0071 15.8 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBY40434.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CBY40434.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CBY40434.1 - 0.19 11.4 0.0 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_2 PF12679.7 CBY40434.1 - 9 5.5 14.0 18 4.5 14.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein HEAT PF02985.22 CBY40435.1 - 2.8e-12 45.8 2.5 0.34 11.3 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CBY40435.1 - 5.6e-09 36.3 0.4 0.0024 18.2 0.0 4.0 2 2 1 3 3 3 3 HEAT repeats Adaptin_N PF01602.20 CBY40435.1 - 1.9e-08 33.4 1.6 2.7e-05 23.0 0.3 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CBY40435.1 - 2.7e-08 34.3 0.6 0.0015 19.1 0.0 4.6 2 2 2 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY40435.1 - 5e-07 29.9 4.3 0.14 12.1 0.5 4.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CBY40435.1 - 0.00076 19.6 0.2 0.051 13.8 0.0 3.3 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CBY40435.1 - 0.026 15.0 0.1 60 4.3 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat DUF667 PF05018.13 CBY40436.1 - 6.4e-95 316.2 0.9 7.1e-95 316.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Pkinase PF00069.25 CBY40437.1 - 4.7e-15 55.7 0.4 7e-15 55.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY40437.1 - 4.1e-05 22.5 0.1 5.6e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CBY40437.1 - 0.00022 20.6 0.2 0.00032 20.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY40437.1 - 0.018 14.9 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CBY40438.1 - 3.6e-21 74.4 37.6 0.00012 22.3 3.3 5.9 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40438.1 - 7.4e-19 66.8 34.0 0.00065 20.3 1.0 5.9 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY40438.1 - 1.9e-09 37.5 33.6 0.0043 17.4 0.8 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY40438.1 - 0.0001 22.2 32.9 0.022 14.8 3.3 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 CBY40438.1 - 0.0013 18.9 12.8 0.028 14.7 0.1 4.4 4 0 0 4 4 4 2 zinc-ribbon IBR PF01485.21 CBY40438.1 - 0.0056 16.9 3.8 0.0056 16.9 3.8 3.4 1 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 CBY40438.1 - 0.012 15.4 0.6 0.012 15.4 0.6 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type PyrI_C PF02748.15 CBY40438.1 - 0.027 14.3 3.4 0.044 13.7 1.8 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TerY_C PF15616.6 CBY40438.1 - 0.051 13.7 2.9 0.27 11.4 0.6 2.5 1 1 1 2 2 2 0 TerY-C metal binding domain zf-ribbon_3 PF13248.6 CBY40438.1 - 0.083 12.3 13.6 3.9 7.0 0.5 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-3CxxC_2 PF17180.4 CBY40438.1 - 0.14 12.9 0.0 0.14 12.9 0.0 4.3 4 1 0 4 4 2 0 Zinc-binding domain zf-Di19 PF05605.12 CBY40438.1 - 0.16 12.3 21.6 0.58 10.5 1.5 4.0 1 1 4 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding HypA PF01155.19 CBY40438.1 - 0.18 11.8 12.6 3.8 7.6 4.3 3.3 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 CBY40438.1 - 0.37 11.3 0.1 0.37 11.3 0.1 5.0 5 0 0 5 5 4 0 Zinc-finger of C2H2 type YhfH PF14149.6 CBY40438.1 - 0.45 10.5 8.9 4.9 7.2 0.4 3.9 4 0 0 4 4 4 0 YhfH-like protein CpXC PF14353.6 CBY40438.1 - 0.49 10.5 18.4 10 6.2 0.4 4.5 1 1 3 4 4 4 0 CpXC protein zf-C2H2_aberr PF17017.5 CBY40438.1 - 0.94 9.6 10.3 0.53 10.4 6.2 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CBY40438.1 - 1.1 9.6 0.0 1.1 9.6 0.0 5.2 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-RING_7 PF02591.15 CBY40438.1 - 1.7 8.9 10.9 54 4.1 0.1 5.3 5 0 0 5 5 5 0 C4-type zinc ribbon domain Trm112p PF03966.16 CBY40438.1 - 2.1 9.0 5.8 3.3 8.3 0.6 3.4 2 2 1 3 3 3 0 Trm112p-like protein Terminase_GpA PF05876.12 CBY40438.1 - 2.7 6.4 11.2 0.2 10.2 2.1 2.2 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Mu-like_Com PF10122.9 CBY40438.1 - 3.2 7.3 9.8 9.2 5.8 6.4 3.3 2 1 0 2 2 2 0 Mu-like prophage protein Com Elf1 PF05129.13 CBY40438.1 - 3.3 7.8 12.3 1 9.4 2.1 3.7 1 1 3 4 4 4 0 Transcription elongation factor Elf1 like Y_phosphatase PF00102.27 CBY40439.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBY40439.1 - 2.6e-06 27.3 0.0 9.7e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY40439.1 - 3.8e-05 23.8 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY40439.1 - 0.017 15.3 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate CCDC-167 PF15188.6 CBY40439.1 - 0.57 10.5 3.9 0.25 11.7 1.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 LSM PF01423.22 CBY40440.1 - 3e-19 68.5 0.0 3.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain RhoGAP PF00620.27 CBY40443.1 - 1.8e-14 53.8 0.6 4.1e-14 52.7 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain C1_2 PF03107.16 CBY40443.1 - 1.2e-06 28.7 3.0 3.1e-06 27.4 3.0 1.7 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 CBY40443.1 - 1.4e-05 24.9 11.0 2.4e-05 24.1 11.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3H2C3 PF17122.5 CBY40443.1 - 0.11 12.6 4.4 0.25 11.4 4.4 1.6 1 1 0 1 1 1 0 Zinc-finger DUF4347 PF14252.6 CBY40443.1 - 0.12 12.2 0.8 0.23 11.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Prok-RING_1 PF14446.6 CBY40443.1 - 0.22 11.5 7.5 0.45 10.5 7.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Tox-URI2 PF15653.6 CBY40443.1 - 0.35 11.2 4.1 0.31 11.3 0.2 2.6 2 1 1 3 3 3 0 URI fold toxin 2 Zf_RING PF16744.5 CBY40443.1 - 0.54 10.4 6.9 1.9 8.7 6.9 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger DZR PF12773.7 CBY40443.1 - 0.57 10.2 7.8 1.1 9.3 7.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon PHD PF00628.29 CBY40443.1 - 0.85 9.6 8.2 1.7 8.6 8.2 1.5 1 0 0 1 1 1 0 PHD-finger DivIC PF04977.15 CBY40443.1 - 6 6.7 11.8 0.5 10.2 0.7 3.4 2 1 0 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 CBY40443.1 - 10 6.3 10.8 0.56 10.3 0.7 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Piwi PF02171.17 CBY40444.1 - 7e-63 212.7 0.0 1.1e-62 212.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 CBY40444.1 - 1.8e-05 24.9 0.5 6.7e-05 23.1 0.5 2.0 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 CBY40444.1 - 0.0016 18.0 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 2 Argonaute linker 1 domain ArgoL2 PF16488.5 CBY40444.1 - 0.0017 18.6 0.0 0.0046 17.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoN PF16486.5 CBY40444.1 - 0.006 17.2 0.1 0.019 15.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute DUF5320 PF17253.2 CBY40444.1 - 1.1 10.4 3.9 10 7.3 3.9 2.6 1 1 0 1 1 1 0 Family of unknown function (DUF5320) NinE PF05322.11 CBY40445.1 - 0.37 10.7 0.2 0.37 10.7 0.2 2.4 2 1 1 3 3 3 0 NINE Protein DUF3330 PF11809.8 CBY40445.1 - 3 7.9 10.0 20 5.3 10.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3330) AMP-binding PF00501.28 CBY40446.1 - 1.9e-76 257.4 0.2 2.4e-76 257.1 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBY40446.1 - 8.5e-17 61.9 0.5 1.5e-16 61.1 0.5 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-H2C2_2 PF13465.6 CBY40447.1 - 6.6e-18 64.3 25.7 1.5e-08 34.7 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY40447.1 - 2.1e-16 59.4 28.2 1.2e-05 25.5 1.6 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf_ZIC PF18366.1 CBY40447.1 - 5.9e-10 39.1 0.4 5.9e-10 39.1 0.4 4.0 5 0 0 5 5 5 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 CBY40447.1 - 2.4e-08 34.1 27.7 0.012 16.4 0.5 5.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY40447.1 - 0.0036 17.6 3.4 6.9 7.1 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CBY40447.1 - 0.0058 16.9 10.0 0.13 12.6 3.4 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-met PF12874.7 CBY40447.1 - 0.12 12.8 6.8 1.9 9.0 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CBY40447.1 - 0.2 11.5 1.7 0.37 10.6 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type CHORD PF04968.12 CBY40447.1 - 1.1 10.0 19.6 3.7 8.3 1.0 4.4 2 1 2 4 4 4 0 CHORD zf-C2H2_6 PF13912.6 CBY40447.1 - 1.7 8.7 10.4 1.5 8.9 0.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY40447.1 - 3.7 7.4 16.4 1.8 8.4 1.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain HNH PF01844.23 CBY40447.1 - 5.8 7.2 7.1 1.1 9.5 0.4 3.0 3 0 0 3 3 3 0 HNH endonuclease zf-C2H2_aberr PF17017.5 CBY40447.1 - 8.1 6.6 13.1 29 4.7 0.4 3.8 1 1 3 4 4 4 0 Aberrant zinc-finger Phospholip_A2_1 PF00068.19 CBY40448.1 - 7.1e-11 42.6 9.6 7.1e-11 42.6 9.6 2.1 2 0 0 2 2 2 1 Phospholipase A2 Piwi PF02171.17 CBY40449.1 - 1.1e-56 192.3 0.0 1.5e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Glycogen_syn PF05693.13 CBY40450.1 - 8.8e-277 919.8 0.0 1e-276 919.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CBY40450.1 - 1e-08 34.9 0.0 0.00078 19.0 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBY40450.1 - 1.4e-06 28.4 0.1 2.9e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CBY40450.1 - 5.1e-06 26.9 0.0 0.02 15.3 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Imm68 PF15583.6 CBY40450.1 - 0.085 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 68 RVT_1 PF00078.27 CBY40451.1 - 2e-06 27.5 0.4 0.011 15.2 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CBY40451.1 - 0.0097 15.6 0.5 0.021 14.5 0.1 1.8 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MyTH4 PF00784.17 CBY40452.1 - 4.2e-61 204.1 0.9 2.8e-30 105.0 0.0 3.0 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 CBY40452.1 - 9.9e-12 45.3 10.3 1.4e-09 38.4 0.0 4.8 7 1 0 7 7 7 2 FERM central domain Myosin_head PF00063.21 CBY40452.1 - 4e-10 38.6 0.0 8.1e-10 37.6 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CBY40452.1 - 7.9e-09 34.5 22.4 0.00032 20.2 0.0 5.9 5 0 0 5 5 5 3 IQ calmodulin-binding motif FERM_N PF09379.10 CBY40452.1 - 9e-08 32.0 0.1 0.02 14.8 0.0 2.9 2 0 0 2 2 2 2 FERM N-terminal domain gpW PF02831.15 CBY40452.1 - 1.5 8.8 5.4 8.8 6.3 0.1 3.4 3 0 0 3 3 3 0 gpW DUF4407 PF14362.6 CBY40453.1 - 0.52 9.6 11.9 4.3 6.6 12.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 CBY40453.1 - 0.79 9.7 0.0 0.79 9.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF4579 PF15158.6 CBY40454.1 - 2.3e-06 27.5 0.1 2.3e-06 27.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) Glycos_transf_2 PF00535.26 CBY40456.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ORC6 PF05460.13 CBY40457.1 - 0.054 12.8 0.0 0.057 12.7 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SASA PF03629.18 CBY40457.1 - 0.059 13.0 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase DUF5064 PF16703.5 CBY40457.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5064) DUF3421 PF11901.8 CBY40458.1 - 1.9e-17 63.3 0.0 1.1e-05 25.4 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) Aldedh PF00171.22 CBY40459.1 - 7e-77 258.9 0.0 8.4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungus-induced PF10917.8 CBY40460.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungus-induced protein Opy2 PF09463.10 CBY40460.1 - 4.4 7.7 8.6 6.7 7.1 0.2 3.3 3 0 0 3 3 3 0 Opy2 protein dsrm PF00035.26 CBY40461.1 - 6.4e-11 42.8 0.6 2.4 8.9 0.0 6.5 6 0 0 6 6 6 4 Double-stranded RNA binding motif PP-binding PF00550.25 CBY40462.1 - 3.4e-10 40.1 0.4 3.4e-10 40.1 0.4 1.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CBY40462.1 - 0.0067 16.6 0.5 0.012 15.8 0.4 1.4 1 1 0 1 1 1 1 Acyl-carrier UTP25 PF06862.12 CBY40463.1 - 2.1e-32 112.5 0.6 2.9e-32 112.1 0.6 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3826 PF12875.7 CBY40463.1 - 5.9e-05 23.3 0.9 0.00014 22.1 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3826) PI3K_1B_p101 PF10486.9 CBY40463.1 - 0.22 9.3 5.7 0.27 9.0 5.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3644 PF12358.8 CBY40463.1 - 0.34 11.4 2.3 0.52 10.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) HECT PF00632.25 CBY40464.1 - 8.3e-86 288.2 0.0 1.8e-85 287.1 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECW1_helix PF18436.1 CBY40464.1 - 4e-06 26.8 3.1 1.2e-05 25.3 3.1 1.8 1 0 0 1 1 1 1 Helical box domain of E3 ubiquitin-protein ligase HECW1 PDZ_6 PF17820.1 CBY40464.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 CBY40464.1 - 0.095 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RNA_pol_Rpb5_N PF03871.14 CBY40464.1 - 3.6 8.2 6.9 28 5.4 1.6 3.8 3 1 1 4 4 4 0 RNA polymerase Rpb5, N-terminal domain TBCC_N PF16752.5 CBY40465.1 - 0.15 12.5 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain zf-H2C2_5 PF13909.6 CBY40466.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-MYND PF01753.18 CBY40467.1 - 3.3e-10 39.9 15.7 3.3e-10 39.9 15.7 3.1 3 0 0 3 3 3 1 MYND finger PDCD2_C PF04194.13 CBY40467.1 - 1.5e-08 34.9 13.0 4.1e-08 33.5 2.3 2.8 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain zf-HIT PF04438.16 CBY40467.1 - 0.0011 18.7 10.9 0.0011 18.7 10.9 2.8 3 0 0 3 3 3 1 HIT zinc finger Glycos_transf_2 PF00535.26 CBY40468.1 - 7.9e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_M16_C PF05193.21 CBY40470.1 - 7e-11 42.5 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain TIM PF00121.18 CBY40470.1 - 0.033 13.6 0.0 0.054 12.9 0.0 1.3 1 1 0 1 1 1 0 Triosephosphate isomerase DUF5638 PF18688.1 CBY40470.1 - 0.12 12.7 0.1 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5638) DUF3402 PF11882.8 CBY40471.1 - 3.5e-59 201.1 15.0 5.3e-37 128.0 2.6 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CBY40471.1 - 7.1e-12 45.1 2.9 2.3e-10 40.2 2.9 2.4 1 1 0 1 1 1 1 N1221-like protein Peptidase_M16 PF00675.20 CBY40472.1 - 8.1e-17 61.6 0.0 2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBY40472.1 - 2.3e-07 31.0 0.0 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain EF-hand_1 PF00036.32 CBY40474.1 - 1.6e-07 30.4 1.3 0.00023 20.5 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY40474.1 - 9.8e-07 28.0 2.9 2.7e-05 23.5 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY40474.1 - 2.3e-06 27.1 2.4 0.0047 16.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBY40474.1 - 0.00091 19.6 2.6 0.023 15.2 2.6 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY40474.1 - 0.0068 16.2 1.5 0.29 11.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair UnbV_ASPIC PF07593.12 CBY40474.1 - 0.073 13.0 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 ASPIC and UnbV Tctex-1 PF03645.13 CBY40475.1 - 1.8e-11 44.2 0.1 2.9e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.24 CBY40476.1 - 4.3e-62 210.5 0.0 5.7e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Phospholip_A2_1 PF00068.19 CBY40479.1 - 2e-10 41.1 11.1 2e-10 41.1 11.1 2.2 2 0 0 2 2 2 1 Phospholipase A2 PriCT_1 PF08708.11 CBY40479.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) LRR_4 PF12799.7 CBY40480.1 - 0.0092 16.4 0.1 0.015 15.7 0.1 1.6 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF3012 PF11216.8 CBY40482.1 - 0.0099 15.9 0.1 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) PH_14 PF17787.1 CBY40482.1 - 0.078 12.8 4.0 0.17 11.8 0.2 2.3 2 0 0 2 2 2 0 PH domain SCVP PF17619.2 CBY40482.1 - 5.2 8.0 9.8 0.9 10.4 0.5 3.1 4 0 0 4 4 4 0 Secreted clade V proteins MBD_C PF14048.6 CBY40484.1 - 3.5e-20 72.5 0.2 5.1e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF3139 PF11337.8 CBY40485.1 - 0.25 12.0 1.2 9.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) DUF4131 PF13567.6 CBY40485.1 - 0.3 10.7 2.1 0.42 10.3 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 CBY40485.1 - 2.7 7.6 10.9 15 5.2 11.1 2.1 1 1 0 1 1 1 0 Tetraspanin family Pkinase PF00069.25 CBY40486.1 - 1.1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40486.1 - 1.2e-18 67.3 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY40486.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CitMHS PF03600.16 CBY40487.1 - 0.65 9.1 24.4 11 5.1 24.3 2.1 1 1 0 1 1 1 0 Citrate transporter SSF PF00474.17 CBY40488.1 - 1.3e-11 44.0 8.5 2.2e-11 43.2 8.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF5056 PF16479.5 CBY40488.1 - 0.29 11.4 1.8 0.54 10.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) GerD PF17898.1 CBY40490.1 - 0.16 11.9 3.9 0.36 10.8 2.0 2.1 2 1 0 2 2 2 0 Spore germination GerD central core domain Slu7 PF11708.8 CBY40491.1 - 9.4e-99 330.5 11.5 9.4e-99 330.5 11.5 3.3 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.9 CBY40491.1 - 0.00033 20.3 32.2 0.00033 20.3 32.2 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.6 CBY40491.1 - 0.056 13.2 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2229 PF09989.9 CBY40491.1 - 3.2 7.3 6.3 7.3 6.2 6.3 1.6 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Prim-Pol PF09250.11 CBY40492.1 - 0.041 14.2 0.0 0.05 14.0 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal GTP1_OBG PF01018.22 CBY40493.1 - 8.7e-34 116.4 3.4 1e-33 116.1 3.4 1.1 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CBY40493.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY40493.1 - 0.00051 19.6 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Hydantoinase_B PF02538.14 CBY40493.1 - 1.1 7.6 4.9 1.3 7.3 4.9 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Sulfotransfer_1 PF00685.27 CBY40494.1 - 8.6e-17 61.5 1.4 9.9e-17 61.3 1.4 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY40494.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family BAF250_C PF12031.8 CBY40494.1 - 0.23 10.7 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Ank_5 PF13857.6 CBY40495.1 - 1.6e-12 47.4 0.1 9.8e-10 38.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY40495.1 - 5.4e-12 46.0 0.5 9.3e-08 32.5 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY40495.1 - 1.8e-09 38.1 0.1 4.4e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CBY40495.1 - 3.5e-09 36.7 0.4 0.0014 19.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CBY40495.1 - 3.1e-05 24.0 0.1 0.42 11.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TENA_THI-4 PF03070.16 CBY40496.1 - 0.0027 17.6 0.2 0.003 17.4 0.2 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PilJ PF13675.6 CBY40496.1 - 0.011 15.8 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2894 PF11445.8 CBY40496.1 - 0.011 16.2 1.0 0.013 16.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) WXG100 PF06013.12 CBY40496.1 - 0.018 15.2 0.6 0.025 14.8 0.6 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG 5_nucleotid PF05761.14 CBY40496.1 - 0.02 13.8 0.5 0.02 13.8 0.5 1.0 1 0 0 1 1 1 0 5' nucleotidase family V-SNARE PF05008.15 CBY40496.1 - 0.023 15.1 2.1 0.3 11.5 0.1 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Uds1 PF15456.6 CBY40496.1 - 0.027 14.7 1.7 0.033 14.4 1.7 1.1 1 0 0 1 1 1 0 Up-regulated During Septation CBP4 PF07960.11 CBY40496.1 - 0.058 13.2 0.8 0.072 12.9 0.8 1.1 1 0 0 1 1 1 0 CBP4 NYD-SP28 PF14772.6 CBY40496.1 - 0.058 13.4 6.2 0.14 12.2 3.7 1.9 1 1 1 2 2 2 0 Sperm tail FAM76 PF16046.5 CBY40496.1 - 0.062 12.6 3.1 0.078 12.3 3.1 1.0 1 0 0 1 1 1 0 FAM76 protein DUF4404 PF14357.6 CBY40496.1 - 0.066 13.9 1.4 0.09 13.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4250 PF14056.6 CBY40496.1 - 0.081 12.9 0.7 0.98 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) FixO PF02433.15 CBY40496.1 - 0.17 11.3 1.0 0.19 11.2 1.0 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO RICH PF05062.12 CBY40496.1 - 0.38 11.1 7.8 0.087 13.2 3.6 2.0 2 1 1 3 3 3 0 RICH domain Phospholip_A2_1 PF00068.19 CBY40497.1 - 1.3e-19 70.8 7.3 1.3e-19 70.8 7.3 2.2 2 0 0 2 2 2 1 Phospholipase A2 PH PF00169.29 CBY40498.1 - 1.4e-06 28.8 1.2 3.7e-06 27.4 1.1 1.8 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 CBY40498.1 - 0.00075 19.9 0.4 0.0078 16.6 0.4 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CBY40498.1 - 0.0044 17.4 0.4 0.0044 17.4 0.4 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PTH2 PF01981.16 CBY40498.1 - 3.9 7.8 10.3 0.66 10.3 4.7 2.5 2 1 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 PLAC8 PF04749.17 CBY40500.1 - 0.00016 22.6 18.4 0.00031 21.7 18.4 1.5 1 1 0 1 1 1 1 PLAC8 family Psb28 PF03912.14 CBY40501.1 - 0.011 16.0 0.6 0.07 13.4 0.0 2.1 2 0 0 2 2 2 0 Psb28 protein NPV_P10 PF05531.12 CBY40501.1 - 0.19 12.2 0.5 6.2 7.4 0.5 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FAIM1 PF06905.13 CBY40502.1 - 4.4e-37 127.4 0.0 5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Adenyl_transf PF04439.12 CBY40502.1 - 0.056 12.5 0.1 0.07 12.2 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Evr1_Alr PF04777.13 CBY40503.1 - 1.8e-17 63.6 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family zf-C2H2_jaz PF12171.8 CBY40503.1 - 0.13 12.6 0.6 0.13 12.6 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RT_RNaseH_2 PF17919.1 CBY40504.1 - 1e-11 44.7 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY40504.1 - 0.0037 17.5 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase KH_5 PF13184.6 CBY40504.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 NusA-like KH domain Kinesin PF00225.23 CBY40506.1 - 8.6e-118 393.1 4.3 8.6e-118 393.1 4.3 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY40506.1 - 8.4e-30 103.7 0.4 8.4e-30 103.7 0.4 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 CBY40506.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain V_ATPase_I PF01496.19 CBY40506.1 - 0.2 9.6 20.8 0.38 8.6 20.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CBY40507.1 - 8.5e-30 104.0 3.2 3.9e-24 85.4 0.0 4.0 2 2 2 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40507.1 - 2.7e-16 59.6 0.0 6.1e-12 45.4 0.0 3.2 1 1 2 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.24 CBY40507.1 - 6e-06 26.9 1.3 2.4e-05 25.0 1.3 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Golgin_A5 PF09787.9 CBY40507.1 - 1.3 8.4 57.4 0.72 9.3 24.7 3.5 1 1 1 3 3 3 0 Golgin subfamily A member 5 Branch PF02485.21 CBY40508.1 - 1.3e-49 169.0 0.1 1.7e-49 168.5 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF2793 PF10983.8 CBY40508.1 - 0.025 14.5 0.3 0.051 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Neur_chan_LBD PF02931.23 CBY40509.1 - 1.7e-66 223.8 4.6 2.2e-66 223.4 4.6 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 CBY40509.1 - 1.6e-30 106.9 12.8 2.7e-30 106.2 12.8 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2417 PF10329.9 CBY40509.1 - 0.12 11.8 7.0 0.26 10.7 7.0 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Kelch_6 PF13964.6 CBY40510.1 - 3.3e-05 24.0 5.1 0.35 11.2 0.2 3.8 2 1 1 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CBY40510.1 - 0.00016 21.2 3.8 0.38 10.4 1.6 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBY40510.1 - 0.00023 21.1 4.9 0.051 13.6 0.2 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY40510.1 - 0.2 11.7 4.2 3.6 7.7 0.2 3.3 3 0 0 3 3 3 0 Kelch motif Ig_3 PF13927.6 CBY40511.1 - 7.4e-11 42.5 0.0 2.8e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Immunoglobulin domain TSP_1 PF00090.19 CBY40511.1 - 9.6e-10 38.5 2.8 9.6e-10 38.5 2.8 2.2 2 0 0 2 2 2 1 Thrombospondin type 1 domain I-set PF07679.16 CBY40511.1 - 1.9e-09 37.4 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY40511.1 - 2.4e-07 31.0 0.0 7.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY40511.1 - 5e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY40511.1 - 0.0001 22.4 0.1 0.69 10.1 0.0 2.5 1 1 1 2 2 2 2 Immunoglobulin V-set domain CarboxypepD_reg PF13620.6 CBY40511.1 - 0.00052 20.2 0.0 0.00095 19.4 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 CBY40511.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) TSP_1 PF00090.19 CBY40512.1 - 1e-09 38.5 2.8 1e-09 38.5 2.8 2.2 2 1 0 2 2 2 1 Thrombospondin type 1 domain CarboxypepD_reg PF13620.6 CBY40512.1 - 0.0002 21.6 0.0 0.00031 21.0 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CBY40512.1 - 0.0096 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Big_1 PF02369.16 CBY40512.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) ECH_1 PF00378.20 CBY40513.1 - 1.9e-26 92.9 0.1 2.3e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY40513.1 - 1.1e-08 35.0 0.1 1.7e-08 34.3 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase M16C_assoc PF08367.11 CBY40514.1 - 1.1e-44 152.5 0.1 1.9e-44 151.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CBY40514.1 - 5.1e-22 78.8 0.0 1.6e-18 67.4 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBY40514.1 - 8.2e-13 48.6 0.9 8.4e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Pardaxin PF07425.11 CBY40514.1 - 0.039 13.6 0.1 5.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Pardaxin Fapy_DNA_glyco PF01149.24 CBY40514.1 - 0.11 13.2 0.1 0.29 11.8 0.0 1.7 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain EF-hand_1 PF00036.32 CBY40516.1 - 1.2e-43 143.5 9.5 4.8e-10 38.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY40516.1 - 7.8e-37 125.6 2.3 5.6e-19 68.4 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY40516.1 - 8.6e-35 118.4 10.0 1.9e-15 56.4 0.4 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBY40516.1 - 3.9e-31 104.3 4.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBY40516.1 - 6.2e-28 95.0 6.4 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBY40516.1 - 5.5e-16 58.7 0.2 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBY40516.1 - 1.2e-10 41.3 0.3 3e-05 23.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY40516.1 - 4e-08 33.6 0.0 0.004 17.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBY40516.1 - 1.2e-06 29.3 0.0 0.00049 20.9 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBY40516.1 - 1.2e-05 25.2 0.0 0.042 13.9 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBY40516.1 - 1.5e-05 25.0 0.8 0.0001 22.4 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 CBY40516.1 - 0.00035 20.3 2.0 0.00038 20.2 2.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Dockerin_1 PF00404.18 CBY40516.1 - 0.00049 20.2 4.7 0.075 13.2 0.4 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF3349 PF11829.8 CBY40516.1 - 0.00082 20.1 0.4 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBY40516.1 - 0.0011 19.0 0.7 0.53 10.2 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF4497 PF14924.6 CBY40516.1 - 0.0017 18.8 0.0 0.9 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 CBY40516.1 - 0.0028 17.6 0.4 0.49 10.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 CBY40516.1 - 0.0032 17.8 0.7 1.7 9.0 0.1 2.6 3 0 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 CBY40516.1 - 0.0095 14.5 0.0 0.0095 14.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Poly_export PF02563.16 CBY40516.1 - 0.011 15.9 0.1 0.53 10.6 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 CBY40516.1 - 0.013 15.4 0.5 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 CBY40516.1 - 0.025 14.9 0.1 9.1 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF2267 PF10025.9 CBY40516.1 - 0.026 14.8 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Fe_hyd_lg_C PF02906.14 CBY40516.1 - 0.046 13.4 0.7 0.19 11.4 0.7 1.9 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 CBY40516.1 - 0.058 13.5 0.3 1.1 9.4 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 CBY40516.1 - 0.074 12.2 0.2 7.5 5.6 0.1 2.4 1 1 0 2 2 2 0 Cache domain TetR_C_7 PF14246.6 CBY40516.1 - 0.085 12.9 0.1 7.3 6.7 0.0 2.8 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Spore_III_AB PF09548.10 CBY40516.1 - 0.12 12.5 0.3 0.25 11.4 0.3 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 CBY40516.1 - 0.13 12.7 0.1 13 6.4 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain SapB_1 PF05184.15 CBY40516.1 - 0.23 11.5 1.2 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 CMD PF02627.20 CBY40516.1 - 0.31 11.1 1.1 6.9 6.8 0.0 2.8 2 2 1 3 3 3 0 Carboxymuconolactone decarboxylase family HLH PF00010.26 CBY40517.1 - 5.6e-15 55.0 0.1 9.8e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BLI1 PF17324.2 CBY40517.1 - 0.021 15.5 5.6 0.58 10.8 0.3 2.3 1 1 1 2 2 2 0 BLOC-1 interactor 1 Endotoxin_N PF03945.14 CBY40517.1 - 0.097 12.4 1.9 0.13 11.9 1.9 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain SVIP PF15811.5 CBY40517.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HD_3 PF13023.6 CBY40518.1 - 0.013 15.4 0.1 0.018 15.0 0.1 1.3 1 1 0 1 1 1 0 HD domain LcrG PF07216.12 CBY40518.1 - 0.038 13.9 0.2 0.041 13.8 0.2 1.2 1 0 0 1 1 1 0 LcrG protein Sugar_tr PF00083.24 CBY40519.1 - 1.3e-11 44.1 5.5 1.5e-11 43.8 5.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY40519.1 - 2.4e-07 30.0 11.7 4.4e-07 29.1 11.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A31 PF05771.11 CBY40520.1 - 0.11 12.5 0.8 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A31 protein Peptidase_S9 PF00326.21 CBY40522.1 - 1.3e-41 142.4 1.4 2.4e-41 141.6 1.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBY40522.1 - 1.4e-38 132.6 0.4 2.5e-38 131.7 0.4 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 CBY40522.1 - 0.0016 18.4 3.8 0.006 16.5 0.1 3.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 CBY40522.1 - 0.022 14.4 0.9 0.1 12.2 0.2 2.3 2 1 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 CBY40522.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Homeodomain PF00046.29 CBY40524.1 - 5.2e-21 74.2 1.0 1.1e-20 73.2 1.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY40524.1 - 0.016 15.1 0.1 0.067 13.1 0.1 2.1 2 0 0 2 2 2 0 Homeobox KN domain EVI2A PF05399.11 CBY40524.1 - 0.43 10.1 7.1 0.13 11.9 0.4 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF3402 PF11882.8 CBY40524.1 - 0.53 9.3 7.3 0.046 12.8 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) DUF1181 PF06680.11 CBY40526.1 - 0.032 14.1 0.3 0.045 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Pkinase PF00069.25 CBY40527.1 - 1.9e-08 34.0 1.9 2.2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40527.1 - 3.7e-07 29.7 0.0 9e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Adeno_100 PF02438.16 CBY40527.1 - 0.0015 16.8 1.3 0.0034 15.6 1.3 1.5 1 0 0 1 1 1 1 Late 100kD protein CwsA PF10814.8 CBY40528.1 - 0.035 14.3 0.3 0.043 14.0 0.3 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA DND1_DSRM PF14709.7 CBY40531.1 - 0.054 13.7 0.1 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2951 PF11166.8 CBY40532.1 - 0.08 13.2 2.0 0.082 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.6 CBY40532.1 - 5.5 8.1 7.7 1.5 9.9 2.8 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Vpu PF00558.19 CBY40533.1 - 0.0052 16.5 0.1 0.0074 16.0 0.1 1.2 1 0 0 1 1 1 1 Vpu protein Comm PF15957.5 CBY40533.1 - 0.062 13.7 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 Commissureless LapA_dom PF06305.11 CBY40533.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 CBY40533.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain CYYR1 PF10873.8 CBY40533.1 - 0.79 10.2 4.7 0.31 11.5 1.6 1.7 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF2283 PF10049.9 CBY40534.1 - 0.054 13.7 0.2 0.095 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) Trypsin PF00089.26 CBY40535.1 - 7.1e-135 447.8 15.6 3.1e-48 164.5 0.1 6.2 6 0 0 6 6 6 6 Trypsin DUF1986 PF09342.11 CBY40535.1 - 4.5e-15 56.1 0.6 0.037 14.4 0.0 6.6 6 1 0 6 6 6 5 Domain of unknown function (DUF1986) Trypsin_2 PF13365.6 CBY40535.1 - 6.8e-07 30.3 0.3 0.02 15.8 0.0 4.5 6 0 0 6 6 6 2 Trypsin-like peptidase domain DUF1265 PF06887.14 CBY40535.1 - 0.19 11.7 0.5 13 5.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) rve PF00665.26 CBY40537.1 - 1.2e-13 51.3 0.0 4.1e-13 49.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY40537.1 - 3e-08 33.6 0.0 3e-08 33.6 0.0 2.9 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H3C2 PF16721.5 CBY40537.1 - 0.012 15.9 0.8 0.067 13.6 0.1 2.5 2 1 1 3 3 3 0 Zinc-finger like, probable DNA-binding zf-H2C2 PF09337.10 CBY40537.1 - 0.038 14.2 0.3 0.038 14.2 0.3 2.1 2 0 0 2 2 2 0 H2C2 zinc finger CbiC PF02570.15 CBY40538.1 - 0.09 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF2570 PF10828.8 CBY40538.1 - 0.22 11.4 10.8 3.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) HAUS6_N PF14661.6 CBY40538.1 - 3.4 7.2 6.7 0.81 9.2 3.4 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Sulfotransfer_1 PF00685.27 CBY40540.1 - 2.6e-26 92.7 0.3 7.2e-26 91.2 0.3 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY40540.1 - 1.2e-07 32.3 0.0 5.8e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY40540.1 - 0.006 16.4 0.0 0.067 13.0 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Glyco_hydro_20 PF00728.22 CBY40542.1 - 0.0091 15.4 0.0 0.043 13.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Sec62 PF03839.16 CBY40543.1 - 5.2e-31 107.8 4.9 7.9e-31 107.3 4.9 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 CBY40543.1 - 0.00017 21.6 1.0 0.0004 20.4 1.0 1.6 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EMC3_TMCO1 PF01956.16 CBY40543.1 - 0.96 9.2 7.8 0.29 10.8 3.3 2.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Pentapeptide_3 PF13576.6 CBY40544.1 - 0.0032 17.6 1.4 0.66 10.2 0.4 3.3 3 0 0 3 3 3 2 Pentapeptide repeats (9 copies) DUF4497 PF14924.6 CBY40545.1 - 0.074 13.5 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Biopterin_H PF00351.21 CBY40546.1 - 1.4e-97 326.7 0.0 1.8e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase pKID PF02173.17 CBY40546.1 - 0.5 9.9 4.4 1.2 8.7 4.4 1.6 1 0 0 1 1 1 0 pKID domain Ribosomal_S8e PF01201.22 CBY40547.1 - 3.9e-47 159.9 15.9 4.1e-46 156.5 15.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 CBY40547.1 - 7.6 5.5 7.3 11 5.0 7.3 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Longin PF13774.6 CBY40548.1 - 2e-25 88.6 0.9 3.6e-25 87.8 0.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CBY40548.1 - 8.2e-15 54.4 0.6 8.2e-15 54.4 0.6 1.6 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 CBY40548.1 - 0.29 11.1 4.6 0.15 12.0 1.9 2.0 2 1 0 2 2 2 0 Sec20 ELM2 PF01448.24 CBY40549.1 - 1.1e-08 35.6 0.2 2.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 ELM2 domain Myb_DNA-bind_7 PF15963.5 CBY40549.1 - 4.5e-08 32.9 5.2 3.8e-05 23.5 0.2 2.7 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBY40549.1 - 7.8e-06 26.0 0.1 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBY40549.1 - 0.0032 17.7 0.4 0.023 15.0 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain End3 PF12761.7 CBY40549.1 - 0.027 14.6 0.3 0.051 13.7 0.3 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Snapin_Pallidin PF14712.6 CBY40549.1 - 0.035 14.5 0.5 0.089 13.2 0.5 1.7 1 0 0 1 1 1 0 Snapin/Pallidin Peptidase_M75 PF09375.10 CBY40549.1 - 0.13 11.7 0.3 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Imelysin XhlA PF10779.9 CBY40549.1 - 0.28 11.4 3.6 0.61 10.3 3.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Bap31_Bap29_C PF18035.1 CBY40549.1 - 0.37 10.8 2.7 1.1 9.3 2.7 1.9 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain UPF0240 PF06784.11 CBY40550.1 - 6.2e-08 32.9 2.5 1.3e-07 31.8 2.5 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) OmpA PF00691.20 CBY40550.1 - 0.053 13.9 0.5 0.15 12.5 0.4 1.8 2 0 0 2 2 2 0 OmpA family O-FucT PF10250.9 CBY40551.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase EF-hand_1 PF00036.32 CBY40552.1 - 1.1e-14 52.8 1.7 1.3e-06 27.6 0.5 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY40552.1 - 6.2e-13 47.5 1.0 7.5e-06 25.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBY40552.1 - 5.8e-12 44.5 2.9 1.1e-05 24.6 0.7 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY40552.1 - 1.8e-09 37.9 0.2 2.1e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY40552.1 - 1.8e-08 34.1 0.6 0.00033 20.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 CBY40552.1 - 0.00054 19.9 0.2 0.23 11.4 0.1 2.0 1 1 1 2 2 2 2 Caleosin related protein EF-hand_10 PF14788.6 CBY40552.1 - 0.0023 17.8 0.7 0.0065 16.3 0.4 1.8 1 1 1 2 2 2 1 EF hand DUF294_C PF10335.9 CBY40552.1 - 0.082 12.7 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain NAD_synthase PF02540.17 CBY40552.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 NAD synthase Arg_decarbox_C PF17944.1 CBY40552.1 - 0.12 13.0 0.4 11 6.7 0.1 2.2 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension DUF755 PF05501.11 CBY40554.1 - 0.002 18.4 21.9 0.002 18.4 21.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.12 CBY40554.1 - 0.017 14.8 17.5 0.023 14.5 17.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Neur_chan_memb PF02932.16 CBY40554.1 - 0.06 13.4 5.1 0.066 13.3 5.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleo_P87 PF07267.11 CBY40554.1 - 0.22 10.3 6.1 0.26 10.1 6.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SURF2 PF05477.11 CBY40554.1 - 0.35 10.5 14.2 0.38 10.4 14.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LRIF1 PF15741.5 CBY40554.1 - 0.37 9.3 17.2 0.38 9.2 17.2 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Raftlin PF15250.6 CBY40554.1 - 0.6 8.8 13.1 0.74 8.5 13.1 1.1 1 0 0 1 1 1 0 Raftlin MAJIN PF15077.6 CBY40554.1 - 0.73 9.6 10.9 0.87 9.3 10.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein FancD2 PF14631.6 CBY40554.1 - 0.88 6.9 8.0 0.95 6.8 8.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 CBY40554.1 - 7.6 6.3 12.7 9.3 6.0 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RT_RNaseH_2 PF17919.1 CBY40556.1 - 5.7e-28 96.9 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY40556.1 - 1.9e-26 92.4 0.0 3.5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY40556.1 - 3e-19 69.4 0.1 8.9e-19 67.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY40556.1 - 1.1e-07 31.8 0.2 2.6e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain COX5B PF01215.19 CBY40556.1 - 0.15 11.8 0.0 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb DUF1179 PF06678.11 CBY40557.1 - 2.3 8.2 6.6 4.9 7.2 6.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) CUB PF00431.20 CBY40558.1 - 1.8e-224 730.0 21.2 1.7e-28 99.2 0.1 12.0 12 0 0 12 12 12 12 CUB domain CUB_2 PF02408.20 CBY40558.1 - 0.019 14.7 24.8 0.35 10.6 0.0 9.1 10 2 0 10 10 10 0 CUB-like domain Pkinase PF00069.25 CBY40559.1 - 2.4e-16 59.9 0.1 3.3e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40559.1 - 1.7e-09 37.4 0.1 2.9e-09 36.6 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY40559.1 - 0.0045 15.8 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY40559.1 - 0.074 12.6 0.2 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Sushi PF00084.20 CBY40560.1 - 4.5e-06 27.2 15.9 0.0062 17.1 6.1 2.5 2 0 0 2 2 2 2 Sushi repeat (SCR repeat) Selenoprotein_S PF06936.11 CBY40560.1 - 1.4 8.7 9.6 3.8 7.3 9.6 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3824 PF12868.7 CBY40560.1 - 3.1 8.4 9.3 0.73 10.5 4.5 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) EMP24_GP25L PF01105.24 CBY40561.1 - 3.6e-11 43.3 0.1 4.2e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CUB PF00431.20 CBY40562.1 - 7.8e-07 29.4 0.1 7.8e-07 29.4 0.1 1.6 2 0 0 2 2 2 1 CUB domain Tir_receptor_C PF07489.11 CBY40562.1 - 0.13 12.2 1.3 0.24 11.4 0.9 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus RXLR PF16810.5 CBY40562.1 - 0.19 12.2 1.3 0.35 11.3 1.3 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF3439 PF11921.8 CBY40562.1 - 0.19 11.7 6.0 0.32 11.0 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 CBY40562.1 - 0.31 11.0 9.4 0.49 10.4 9.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CBY40562.1 - 0.63 8.0 5.1 0.77 7.7 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 CBY40562.1 - 7.2 4.7 10.7 11 4.1 10.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.22 CBY40563.1 - 1.9e-15 56.8 0.0 2.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Vps39_1 PF10366.9 CBY40564.1 - 1.2e-18 67.4 0.4 1.2e-18 67.4 0.4 3.2 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CBY40564.1 - 1e-17 64.6 0.6 1.6e-16 60.7 0.0 3.1 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CBY40564.1 - 2.9e-09 37.0 0.4 6.8e-09 35.7 0.4 1.6 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CBY40564.1 - 6.1e-08 32.6 7.6 0.0032 17.3 0.2 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS Nup192 PF11894.8 CBY40565.1 - 2.2e-30 104.8 0.0 2.6e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Clathrin_H_link PF13838.6 CBY40565.1 - 0.13 12.2 0.2 0.89 9.5 0.1 2.1 2 0 0 2 2 2 0 Clathrin-H-link Mating_N PF12731.7 CBY40565.1 - 0.18 11.9 0.4 1.7 8.8 0.1 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 BRCT_2 PF16589.5 CBY40566.1 - 0.00046 20.5 3.6 0.43 11.0 0.1 3.1 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY40566.1 - 0.014 15.7 0.4 0.95 9.8 0.1 3.0 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CBY40566.1 - 0.087 12.9 0.0 5 7.2 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 CBY40567.1 - 9.8e-34 116.9 0.0 1.8e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40567.1 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY40567.1 - 4.4e-09 36.0 0.0 7.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY40567.1 - 7.2e-05 22.2 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY40567.1 - 0.00018 21.5 0.0 0.00033 20.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBY40567.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBY40567.1 - 0.002 17.2 0.2 0.019 13.9 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY40567.1 - 0.011 15.3 0.2 0.085 12.5 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CBY40567.1 - 0.012 14.4 0.0 0.028 13.2 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Trypsin PF00089.26 CBY40568.1 - 3.6e-42 144.6 0.5 5.2e-42 144.1 0.5 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY40568.1 - 4.1e-09 37.5 0.0 8.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF316 PF03761.15 CBY40568.1 - 0.00029 20.5 0.5 0.23 11.0 0.0 2.7 3 0 0 3 3 3 2 Chymotrypsin family Peptidase-S1 Dynein_light PF01221.18 CBY40570.1 - 0.00088 19.5 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2399 PF09664.10 CBY40571.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) MAP65_ASE1 PF03999.12 CBY40571.1 - 6.1 5.4 13.9 0.014 14.1 1.3 1.9 1 1 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Kelch_5 PF13854.6 CBY40572.1 - 0.0035 17.3 0.6 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Kelch motif PFU PF09070.11 CBY40572.1 - 0.12 12.6 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Actin PF00022.19 CBY40575.1 - 5.3e-29 101.1 0.0 6.1e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CBY40575.1 - 0.085 11.4 0.0 0.096 11.2 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Actin PF00022.19 CBY40576.1 - 1.2e-61 208.6 0.0 1.3e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Actin Med27 PF11571.8 CBY40577.1 - 2.5e-27 95.0 1.0 2.9e-27 94.8 1.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 27 Med27 PF11571.8 CBY40578.1 - 3.1e-21 75.5 1.0 2.4e-20 72.7 0.4 2.4 2 0 0 2 2 2 1 Mediator complex subunit 27 Ank_4 PF13637.6 CBY40580.1 - 0.00017 22.0 0.0 0.0006 20.3 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY40580.1 - 0.0064 16.8 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY40580.1 - 0.031 14.9 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Plexin_cytopl PF08337.12 CBY40581.1 - 2.8e-54 184.7 0.5 3.4e-54 184.5 0.5 1.0 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain Phage_int_SAM_1 PF02899.17 CBY40581.1 - 0.084 13.2 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Plexin_cytopl PF08337.12 CBY40582.1 - 1.1e-41 143.2 0.0 1.7e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain TIG PF01833.24 CBY40582.1 - 1.1e-15 57.4 2.7 1.5e-09 37.7 0.0 3.0 3 0 0 3 3 3 2 IPT/TIG domain Chordopox_A13L PF05961.11 CBY40582.1 - 0.0032 17.7 0.6 0.0081 16.4 0.6 1.7 1 0 0 1 1 1 1 Chordopoxvirus A13L protein 60KD_IMP PF02096.20 CBY40582.1 - 0.015 15.2 0.8 0.026 14.4 0.8 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein ERGIC_N PF13850.6 CBY40582.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sigma_reg_N PF13800.6 CBY40582.1 - 0.083 13.2 1.3 0.26 11.6 1.3 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Opy2 PF09463.10 CBY40582.1 - 0.45 10.9 3.1 1.1 9.6 3.1 1.6 1 0 0 1 1 1 0 Opy2 protein ETF_QO PF05187.13 CBY40583.1 - 1.1e-43 147.5 0.0 2.1e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CBY40583.1 - 1.4e-07 31.4 0.5 0.001 18.8 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBY40583.1 - 3.1e-06 27.3 0.1 2.8e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY40583.1 - 3.2e-06 26.6 0.0 9.6e-06 25.0 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBY40583.1 - 6.8e-05 22.2 0.0 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CBY40583.1 - 0.00012 21.3 1.6 0.0085 15.2 1.5 2.2 1 1 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 CBY40583.1 - 0.00023 21.7 3.3 0.00052 20.6 3.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 CBY40583.1 - 0.00031 21.2 0.1 1.7 9.2 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBY40583.1 - 0.00035 19.9 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CBY40583.1 - 0.001 17.8 0.2 0.0016 17.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 CBY40583.1 - 0.0016 18.4 0.1 0.0034 17.4 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_17 PF13534.6 CBY40583.1 - 0.0036 17.8 0.6 0.0083 16.6 0.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY40583.1 - 0.0037 17.4 2.3 0.0099 16.0 2.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 CBY40583.1 - 0.0082 15.4 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBY40583.1 - 0.016 14.3 0.2 0.03 13.4 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_21 PF14697.6 CBY40583.1 - 0.044 13.9 1.8 0.088 13.0 1.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 CBY40583.1 - 0.048 12.5 0.1 0.6 8.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_2 PF12797.7 CBY40583.1 - 0.055 13.6 2.1 0.14 12.3 2.1 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_oxidored PF12831.7 CBY40583.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 CBY40583.1 - 0.18 10.9 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 CBY40583.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_10 PF13237.6 CBY40583.1 - 0.23 11.6 7.1 0.32 11.1 5.7 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 CBY40583.1 - 0.42 10.5 5.1 0.17 11.7 2.3 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 CBY40583.1 - 1.7 8.8 5.3 1.2 9.3 2.9 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_4 PF12800.7 CBY40583.1 - 6.1 7.6 7.9 3 8.6 4.8 2.1 2 0 0 2 2 1 0 4Fe-4S binding domain ARGLU PF15346.6 CBY40584.1 - 1.6e-40 138.5 21.5 1.6e-40 138.5 21.5 2.0 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Arena_nucleocap PF00843.17 CBY40584.1 - 0.00071 18.6 1.8 0.00071 18.6 1.8 1.5 1 1 0 1 1 1 1 Arenavirus nucleocapsid N-terminal domain CCDC-167 PF15188.6 CBY40584.1 - 0.0027 18.0 6.0 0.0027 18.0 6.0 3.2 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 167 Caldesmon PF02029.15 CBY40584.1 - 7.8 5.1 32.9 13 4.4 32.9 1.2 1 0 0 1 1 1 0 Caldesmon MH2 PF03166.14 CBY40585.1 - 2.8e-46 158.1 0.1 4.9e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY40585.1 - 7.4e-11 42.2 0.3 1.6e-10 41.1 0.3 1.6 1 0 0 1 1 1 1 MH1 domain PHD PF00628.29 CBY40586.1 - 1.7e-11 43.8 10.5 1.7e-11 43.8 10.5 2.2 3 0 0 3 3 3 1 PHD-finger WSD PF15613.6 CBY40586.1 - 5.8e-07 29.9 0.1 5.8e-07 29.9 0.1 2.1 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 CBY40586.1 - 0.0026 17.3 4.0 0.0026 17.3 4.0 2.3 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 CBY40586.1 - 0.025 14.9 4.6 0.025 14.9 4.6 2.1 2 0 0 2 2 2 0 C1 domain zf-RRPl_C4 PF17026.5 CBY40586.1 - 0.1 12.7 6.1 0.47 10.6 6.1 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 CBY40586.1 - 3.1 7.9 9.2 5.9 7.0 0.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 CBY40586.1 - 6.4 6.9 9.4 24 5.0 9.4 1.9 1 1 0 1 1 1 0 Transposase zinc-binding domain Pinin_SDK_memA PF04696.13 CBY40587.1 - 4.4e-26 91.5 22.1 4.4e-26 91.5 22.1 2.3 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF1117 PF06547.12 CBY40587.1 - 1.3 9.6 9.3 0.78 10.3 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) DUF1664 PF07889.12 CBY40587.1 - 4.3 7.4 9.0 1.2 9.2 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TRAM_LAG1_CLN8 PF03798.16 CBY40588.1 - 3.4e-16 59.6 14.9 3.4e-16 59.6 14.9 1.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CBY40588.1 - 2.5e-15 55.9 0.0 2.5e-15 55.9 0.0 2.4 3 0 0 3 3 3 1 TRAM1-like protein FAM219A PF15260.6 CBY40589.1 - 4.3e-10 40.0 0.6 4.6e-10 39.9 0.6 1.1 1 0 0 1 1 1 1 Protein family FAM219A Ras PF00071.22 CBY40590.1 - 1.4e-56 190.6 0.0 1.5e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY40590.1 - 2.7e-24 85.7 0.0 3.6e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY40590.1 - 1.6e-10 40.7 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBY40590.1 - 0.00016 21.3 0.2 0.00026 20.6 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBY40590.1 - 0.0029 17.1 0.0 0.004 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY40590.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CBY40590.1 - 0.038 13.7 0.0 7.1 6.4 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Phage_integrase PF00589.22 CBY40592.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family RR_TM4-6 PF06459.12 CBY40592.1 - 0.44 10.3 7.7 4.2 7.1 4.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 API5 PF05918.11 CBY40593.1 - 0.011 14.6 6.5 0.023 13.5 6.4 1.6 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3012 PF11216.8 CBY40593.1 - 0.47 10.5 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) ParE_toxin PF05016.15 CBY40593.1 - 0.97 10.1 4.3 0.75 10.5 0.8 2.6 3 1 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE RVT_1 PF00078.27 CBY40594.1 - 4.4e-07 29.6 0.0 9.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY40594.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Flavodoxin_3 PF12641.7 CBY40596.1 - 0.0099 15.6 0.6 0.025 14.3 0.1 1.9 2 0 0 2 2 2 1 Flavodoxin domain KASH_CCD PF14662.6 CBY40596.1 - 0.29 10.9 17.0 0.066 13.0 8.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3450 PF11932.8 CBY40596.1 - 0.43 9.8 11.1 0.24 10.7 6.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 CBY40596.1 - 0.48 9.3 5.1 0.62 8.9 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pox_A_type_inc PF04508.12 CBY40596.1 - 1.7 8.7 5.9 22 5.1 0.4 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2680 PF10925.8 CBY40596.1 - 2.2 8.4 9.8 0.33 11.0 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) TcpS PF17456.2 CBY40596.1 - 8.3 6.4 12.4 2.3 8.3 1.2 2.3 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S DUF1681 PF07933.14 CBY40597.1 - 1.7e-52 177.1 0.0 2.9e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pkinase PF00069.25 CBY40598.1 - 3.5e-67 226.6 0.0 4.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40598.1 - 1.1e-33 116.6 0.0 1.9e-33 115.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY40598.1 - 9.9e-06 25.6 0.4 7.8e-05 22.7 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY40598.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY40598.1 - 0.0019 17.6 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY40598.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.8 3 0 0 3 3 3 0 Kinase-like Apt1 PF10351.9 CBY40598.1 - 0.13 11.1 7.6 0.17 10.7 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyco_hydro_63N PF16923.5 CBY40599.1 - 1.3e-31 110.5 2.0 1.7e-31 110.1 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain DUF2914 PF11141.8 CBY40599.1 - 0.018 14.8 0.8 0.055 13.2 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) ADAM_spacer1 PF05986.14 CBY40599.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Ank_2 PF12796.7 CBY40600.1 - 5.1e-17 62.2 0.0 4e-10 40.1 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY40600.1 - 5.6e-17 61.9 0.1 7e-10 39.3 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY40600.1 - 1.1e-14 53.1 0.0 0.00033 20.9 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CBY40600.1 - 1.2e-13 50.9 0.1 1.4e-05 25.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CBY40600.1 - 2.9e-12 46.6 0.0 1.9e-06 28.0 0.0 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DHHC PF01529.20 CBY40600.1 - 4e-12 46.4 8.0 4e-12 46.4 8.0 2.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase PTB PF08416.13 CBY40601.1 - 4.2e-17 62.5 0.0 5.5e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosine-binding domain EGF PF00008.27 CBY40602.1 - 3.5e-60 199.8 153.7 5.2e-09 36.2 5.5 13.3 13 1 0 13 13 13 11 EGF-like domain hEGF PF12661.7 CBY40602.1 - 3.9e-33 112.9 131.7 6.3e-06 26.6 6.0 13.3 13 0 0 13 13 13 9 Human growth factor-like EGF EGF_2 PF07974.13 CBY40602.1 - 3.1e-18 65.8 186.7 0.0011 19.3 6.3 13.6 13 1 0 13 13 13 11 EGF-like domain EGF_CA PF07645.15 CBY40602.1 - 1.6e-17 63.4 180.4 4.6e-07 29.9 11.5 13.1 8 4 6 14 14 14 6 Calcium-binding EGF domain VWC PF00093.18 CBY40602.1 - 8.6e-05 22.8 9.9 8.6e-05 22.8 9.9 11.1 3 3 3 6 6 6 1 von Willebrand factor type C domain cEGF PF12662.7 CBY40602.1 - 0.005 16.8 2.8 0.005 16.8 2.8 12.5 11 1 0 11 11 11 6 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY40602.1 - 0.017 15.3 8.9 0.017 15.3 8.9 13.2 12 2 1 13 13 13 0 EGF domain FXa_inhibition PF14670.6 CBY40602.1 - 5.3 7.4 140.1 0.67 10.3 3.6 12.3 7 2 5 12 12 12 0 Coagulation Factor Xa inhibitory site LLC1 PF14945.6 CBY40604.1 - 1.1e-06 29.2 0.3 2.5e-05 24.8 0.2 2.2 1 1 1 2 2 2 1 Normal lung function maintenance, Low in Lung Cancer 1 protein Ldl_recept_a PF00057.18 CBY40604.1 - 3.5e-05 23.9 3.2 3.5e-05 23.9 3.2 2.9 3 1 0 3 3 3 1 Low-density lipoprotein receptor domain class A PcfK PF14058.6 CBY40605.1 - 0.21 11.9 0.7 9.3 6.5 0.1 2.4 2 0 0 2 2 2 0 PcfK-like protein DnaJ PF00226.31 CBY40606.1 - 2.8e-24 85.0 0.9 3.1e-24 84.9 0.9 1.0 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 CBY40607.1 - 1.4e-09 38.0 20.8 4.4e-05 23.7 0.2 4.1 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-DBF PF07535.12 CBY40607.1 - 0.0008 19.5 12.6 0.084 13.0 0.1 3.6 3 0 0 3 3 3 2 DBF zinc finger Methyltr_RsmF_N PF17125.5 CBY40607.1 - 0.054 14.0 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF zf-C2H2_2 PF12756.7 CBY40607.1 - 0.25 11.7 12.3 9.6 6.6 2.1 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBY40607.1 - 0.29 11.5 20.7 0.77 10.1 0.1 4.3 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Asp-B-Hydro_N PF05279.11 CBY40607.1 - 4.1 7.4 12.7 1.1 9.3 8.9 1.8 1 1 1 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF3449 PF11931.8 CBY40607.1 - 5 6.9 18.5 0.78 9.5 3.3 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) RRP36 PF06102.12 CBY40608.1 - 7.6e-30 104.1 27.3 7.6e-30 104.1 27.3 1.8 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 EGF_CA PF07645.15 CBY40610.1 - 1.5e-84 277.9 180.8 4.8e-11 42.7 11.1 11.2 11 0 0 11 11 11 10 Calcium-binding EGF domain EGF_3 PF12947.7 CBY40610.1 - 1.6e-79 261.8 183.2 5.2e-10 39.3 9.9 10.4 10 0 0 10 10 10 10 EGF domain cEGF PF12662.7 CBY40610.1 - 2.2e-50 168.2 90.8 1.7e-06 27.8 2.0 11.2 10 0 0 10 10 10 10 Complement Clr-like EGF-like EGF PF00008.27 CBY40610.1 - 4.2e-38 129.3 134.6 1.4e-05 25.3 3.3 11.4 10 2 1 11 11 11 10 EGF-like domain EGF_MSP1_1 PF12946.7 CBY40610.1 - 2.1e-24 85.2 138.5 3.1e-05 23.9 6.0 10.5 10 0 0 10 10 10 10 MSP1 EGF domain 1 hEGF PF12661.7 CBY40610.1 - 2.8e-14 53.1 143.4 0.00011 22.7 3.8 13.8 16 0 0 16 16 16 10 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY40610.1 - 5.7e-09 36.1 139.5 0.021 15.1 4.2 10.5 7 3 3 10 10 10 7 Coagulation Factor Xa inhibitory site Cu-oxidase_3 PF07732.15 CBY40611.1 - 2.2e-36 124.5 0.0 4.6e-35 120.2 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CBY40611.1 - 1.9e-12 47.1 0.2 1.2e-08 34.8 0.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 CBY40611.1 - 2e-08 34.5 0.1 1.6e-05 25.1 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase VP4_haemagglut PF00426.18 CBY40611.1 - 0.079 13.2 0.0 0.63 10.2 0.0 2.4 2 1 1 3 3 3 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain FPL PF09758.9 CBY40612.1 - 1.6e-59 200.2 7.3 1.6e-59 200.2 7.3 2.4 3 0 0 3 3 3 1 Uncharacterised conserved protein zf-C2H2 PF00096.26 CBY40614.1 - 0.00012 22.3 10.5 0.00048 20.4 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40614.1 - 0.0034 18.1 1.2 0.0034 18.1 1.2 3.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY40614.1 - 1.8 9.1 15.2 6.1 7.5 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.25 CBY40616.1 - 3.9e-10 39.5 0.0 6.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40616.1 - 3.2e-06 26.6 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1827 PF08860.10 CBY40616.1 - 0.061 13.6 0.7 7.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) DUF3896 PF13035.6 CBY40616.1 - 0.43 10.8 2.1 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Scramblase PF03803.15 CBY40617.1 - 1.5e-18 67.0 0.0 2.4e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase ILEI PF15711.5 CBY40618.1 - 7.7e-21 74.4 0.1 1.4e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Interleukin-like EMT inducer zf-RRN7 PF11781.8 CBY40619.1 - 0.02 14.6 0.9 0.04 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Auto_anti-p27 PF06677.12 CBY40619.1 - 0.2 11.8 1.2 0.38 10.9 1.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Apt1 PF10351.9 CBY40620.1 - 0.018 14.0 18.8 0.027 13.4 18.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 CBY40620.1 - 0.11 10.8 8.8 0.13 10.5 8.8 1.0 1 0 0 1 1 1 0 Menin NapB PF03892.14 CBY40620.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.3 2 1 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) DUF4614 PF15391.6 CBY40620.1 - 2.1 8.3 25.3 0.33 10.9 16.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) V_ATPase_I PF01496.19 CBY40620.1 - 6.6 4.5 7.2 1.3 6.9 1.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 CBY40620.1 - 7.8 3.5 12.7 8.9 3.3 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 CBY40620.1 - 7.9 6.3 24.1 11 5.8 24.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5099 PF17025.5 CBY40622.1 - 0.02 15.3 0.6 0.023 15.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Y_phosphatase PF00102.27 CBY40623.1 - 2.4e-129 429.9 0.0 3.3e-73 246.1 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase fn3 PF00041.21 CBY40623.1 - 2.2e-22 79.2 1.1 3.2e-08 33.8 0.0 5.1 5 0 0 5 5 5 3 Fibronectin type III domain DSPc PF00782.20 CBY40623.1 - 3.5e-10 39.8 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain CarboxypepD_reg PF13620.6 CBY40623.1 - 0.00062 20.0 1.0 0.097 13.0 0.1 3.3 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Y_phosphatase3 PF13350.6 CBY40623.1 - 0.0063 16.5 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family Ig_2 PF13895.6 CBY40623.1 - 0.069 13.5 0.0 1.5 9.2 0.0 3.0 2 0 0 2 2 2 0 Immunoglobulin domain PTPlike_phytase PF14566.6 CBY40623.1 - 0.14 12.3 0.0 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate fn3_2 PF16893.5 CBY40623.1 - 0.17 12.1 0.0 13 6.1 0.0 3.2 3 0 0 3 3 3 0 Fibronectin type III domain Dimerisation PF08100.11 CBY40624.1 - 0.018 15.0 0.1 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 Dimerisation domain Vac14_Fig4_bd PF11916.8 CBY40625.1 - 6.8e-51 172.5 0.8 1.2e-50 171.6 0.8 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Cnd1 PF12717.7 CBY40625.1 - 0.035 14.2 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF4485 PF14846.6 CBY40625.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) MARVEL PF01284.23 CBY40626.1 - 1.5e-10 41.3 13.8 3.8e-10 40.0 13.8 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF4173 PF13777.6 CBY40626.1 - 0.0082 15.6 1.9 0.0082 15.6 1.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4173) DUF1218 PF06749.12 CBY40626.1 - 8.5 7.0 14.9 59 4.3 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DNA_pol_B_2 PF03175.13 CBY40627.1 - 3.4e-14 52.6 2.3 1e-06 28.0 0.1 2.7 3 0 0 3 3 3 2 DNA polymerase type B, organellar and viral DNA_pol_B PF00136.21 CBY40627.1 - 0.09 11.5 0.4 1.6 7.4 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase family B DUF3295 PF11702.8 CBY40627.1 - 0.83 8.9 3.4 1.3 8.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) LRR_4 PF12799.7 CBY40629.1 - 7.3e-19 67.6 24.2 7e-06 26.3 0.9 5.9 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY40629.1 - 3.4e-14 52.3 25.1 8e-06 25.5 0.9 4.8 3 2 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBY40629.1 - 2.3e-12 46.8 10.0 9.6e-07 28.5 0.0 4.1 2 2 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 CBY40629.1 - 8.3e-07 28.6 15.1 1.8 8.8 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CBY40629.1 - 0.0021 18.4 24.6 0.73 10.6 0.4 7.8 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_2 PF07723.13 CBY40629.1 - 0.17 12.6 10.5 32 5.4 0.2 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat DEAD PF00270.29 CBY40630.1 - 4.4e-43 147.1 0.0 1.1e-42 145.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY40630.1 - 1.5e-32 112.3 0.0 5.3e-32 110.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY40630.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 CBY40630.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Peptidase_C1 PF00112.23 CBY40632.1 - 6.2e-78 261.8 5.3 1e-77 261.1 5.3 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBY40632.1 - 1.6e-14 54.0 1.3 2.8e-14 53.3 1.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cg6151-P PF10233.9 CBY40632.1 - 4.9e-08 33.3 2.5 8.6e-08 32.5 2.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Peptidase_C1_2 PF03051.15 CBY40632.1 - 0.044 12.6 2.1 3.8 6.2 0.3 2.2 2 0 0 2 2 2 0 Peptidase C1-like family DUF2981 PF11200.8 CBY40632.1 - 0.29 10.8 1.6 0.34 10.6 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) SseC PF04888.12 CBY40632.1 - 3.3 7.2 7.9 0.081 12.5 1.6 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TFIIA PF03153.13 CBY40633.1 - 3.8e-12 46.9 11.9 2.4e-11 44.3 11.9 1.9 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.6 CBY40636.1 - 1.5e-10 40.8 12.7 2.3e-10 40.1 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY40636.1 - 0.0014 18.4 12.9 0.0026 17.6 12.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY40636.1 - 0.0065 16.8 15.4 0.013 15.8 15.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBY40636.1 - 0.41 10.6 15.6 0.84 9.6 15.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FPN1 PF06963.12 CBY40637.1 - 2.8e-78 263.4 18.6 3.4e-78 263.2 18.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MscL PF01741.18 CBY40637.1 - 0.21 11.9 6.7 37 4.6 6.7 2.6 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL MKLP1_Arf_bdg PF16540.5 CBY40639.1 - 3.4e-13 49.6 13.1 1.9e-11 43.9 6.0 3.5 2 1 0 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 APG6_N PF17675.1 CBY40639.1 - 0.017 15.6 13.3 0.017 15.6 13.3 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CBY40639.1 - 3.9 5.3 15.2 7.6 4.3 15.2 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.18 CBY40640.1 - 2.9e-40 138.2 0.4 3.9e-40 137.8 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ig_3 PF13927.6 CBY40641.1 - 1.7e-12 47.7 0.5 1.1e-07 32.3 0.0 4.5 3 0 0 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY40641.1 - 8.2e-12 45.0 0.1 8.6e-08 32.2 0.0 4.3 4 1 0 4 4 4 2 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY40641.1 - 7.2e-08 32.7 0.1 0.0017 18.7 0.0 3.5 3 0 0 3 3 3 2 Immunoglobulin domain ig PF00047.25 CBY40641.1 - 4.1e-05 23.7 0.1 0.0025 17.9 0.0 3.1 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY40641.1 - 0.00065 19.8 0.0 0.0076 16.4 0.0 2.7 1 1 0 1 1 1 1 Immunoglobulin V-set domain Receptor_2B4 PF11465.8 CBY40641.1 - 0.077 13.2 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Ig_4 PF16680.5 CBY40641.1 - 0.095 13.0 0.1 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain S1FA PF04689.13 CBY40641.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA binding protein S1FA PSCyt3 PF07627.11 CBY40642.1 - 0.073 13.4 0.1 0.078 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) PhoLip_ATPase_N PF16209.5 CBY40644.1 - 3.2e-20 71.6 1.6 5.1e-20 70.9 1.6 1.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBY40644.1 - 0.00038 20.0 0.0 0.0011 18.5 0.0 1.8 1 1 1 2 2 2 1 E1-E2 ATPase OLF PF02191.16 CBY40646.1 - 1.1e-33 116.9 0.0 1.5e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Olfactomedin-like domain FCH PF00611.23 CBY40647.1 - 0.0016 18.7 0.4 0.0016 18.7 0.4 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Tox-REase-5 PF15648.6 CBY40647.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.1 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF2681 PF10883.8 CBY40648.1 - 0.0031 17.9 0.2 0.0038 17.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) CD34_antigen PF06365.12 CBY40648.1 - 0.005 16.5 0.0 0.0057 16.3 0.0 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family Ly49 PF08391.10 CBY40648.1 - 0.029 14.7 0.7 0.035 14.5 0.7 1.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Nucleoside_tran PF01733.18 CBY40648.1 - 0.081 12.3 0.7 0.089 12.2 0.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter WBP-1 PF11669.8 CBY40648.1 - 0.13 13.0 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 LapA_dom PF06305.11 CBY40648.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NicO PF03824.16 CBY40648.1 - 0.24 10.7 0.0 0.28 10.5 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Astacin PF01400.24 CBY40650.1 - 3e-20 72.6 0.0 5.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Kelch_6 PF13964.6 CBY40650.1 - 0.00046 20.4 0.1 6.1 7.3 0.0 3.8 2 1 1 3 3 3 2 Kelch motif FSA_C PF10479.9 CBY40650.1 - 3.7 5.6 12.7 5.3 5.1 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase PF00069.25 CBY40652.1 - 6.5e-38 130.6 0.0 8.1e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40652.1 - 8.1e-29 100.7 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY40652.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBY40652.1 - 0.0028 16.8 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CBY40652.1 - 0.008 15.2 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Phostensin PF13914.6 CBY40653.1 - 0.059 14.0 1.6 0.062 13.9 0.9 1.5 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Steroid_dh PF02544.16 CBY40654.1 - 1.4e-51 174.4 1.6 2.8e-51 173.5 1.6 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBY40654.1 - 6.5e-05 22.6 0.3 0.00011 21.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PRP38 PF03371.15 CBY40655.1 - 1.8e-06 27.9 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Recombinase PF07508.13 CBY40656.1 - 0.058 13.8 1.8 0.28 11.6 1.8 2.0 1 1 0 1 1 1 0 Recombinase RNA_pol PF00940.19 CBY40657.1 - 3.4e-96 322.6 0.0 5.3e-96 322.0 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase DUF4522 PF15022.6 CBY40658.1 - 0.039 14.2 0.1 0.061 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) RNA_pol_Rpb5_C PF01191.19 CBY40659.1 - 1.3e-19 69.8 0.2 1.4e-19 69.7 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain DUF2072 PF09845.9 CBY40662.1 - 0.17 12.1 2.3 8.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein Sad1_UNC PF07738.13 CBY40663.1 - 2.8e-33 114.7 0.0 5.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Lip_prot_lig_C PF10437.9 CBY40663.1 - 0.099 12.6 0.2 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus bZIP_2 PF07716.15 CBY40666.1 - 0.0094 16.0 1.1 0.025 14.7 1.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_2 PF07716.15 CBY40667.1 - 7.5e-12 45.2 12.1 7.5e-12 45.2 12.1 1.9 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY40667.1 - 0.0019 18.3 9.7 0.0019 18.3 9.7 1.5 1 1 1 2 2 2 1 bZIP transcription factor Fib_alpha PF08702.10 CBY40667.1 - 0.34 11.1 2.7 0.34 11.1 2.7 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MRG PF05712.13 CBY40669.1 - 5.6e-10 38.8 0.9 3.5e-08 33.0 0.9 2.1 1 1 0 1 1 1 1 MRG zf-C2H2 PF00096.26 CBY40671.1 - 5.8e-28 95.8 78.4 0.00027 21.2 0.2 10.8 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY40671.1 - 4.3e-27 92.5 80.7 0.002 18.8 1.4 10.7 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY40671.1 - 2.7e-19 68.7 76.1 0.0025 18.1 0.8 10.2 9 1 0 9 9 9 8 Zinc-finger double domain zf-C2H2_11 PF16622.5 CBY40671.1 - 5.2e-09 35.7 52.6 0.0002 21.1 1.5 10.3 10 0 0 10 10 10 4 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY40671.1 - 1.5e-07 31.3 22.7 0.00019 21.3 2.3 11.5 11 2 0 11 11 11 4 C2H2-type zinc finger RNHCP PF12647.7 CBY40671.1 - 4.2e-06 26.6 42.4 0.018 15.0 0.2 9.2 10 0 0 10 10 10 3 RNHCP domain CpXC PF14353.6 CBY40671.1 - 6.5e-06 26.2 52.2 0.2 11.7 2.6 9.0 3 3 6 9 9 9 4 CpXC protein zf-C2H2_jaz PF12171.8 CBY40671.1 - 3.3e-05 24.0 81.3 0.0018 18.5 3.6 10.3 10 0 0 10 10 9 3 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CBY40671.1 - 3.6e-05 23.8 60.1 0.032 14.4 0.9 9.6 8 2 1 9 9 9 2 Zinc ribbon domain zf_UBZ PF18439.1 CBY40671.1 - 0.00012 21.6 52.3 0.89 9.2 0.4 11.9 13 0 0 13 13 13 3 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 CBY40671.1 - 0.00059 20.1 64.9 0.0048 17.3 1.8 10.2 10 0 0 10 10 10 3 Zinc-finger of C2H2 type Spt46 PF17734.1 CBY40671.1 - 0.019 14.8 1.6 0.019 14.8 1.6 5.9 3 3 3 6 6 6 0 Spermatogenesis-associated protein 46 zf-C2H2_8 PF15909.5 CBY40671.1 - 0.033 14.5 55.2 0.38 11.1 9.9 5.9 3 3 2 6 6 6 0 C2H2-type zinc ribbon Kp4 PF09044.10 CBY40671.1 - 0.04 14.0 6.6 6.3 6.9 0.1 4.7 5 0 0 5 5 5 0 Kp4 zf-C2HC_2 PF13913.6 CBY40671.1 - 0.087 12.7 0.4 0.087 12.7 0.4 10.2 10 2 0 10 10 10 0 zinc-finger of a C2HC-type TraC PF07820.12 CBY40671.1 - 0.22 11.9 9.9 1.9 8.8 0.7 3.0 3 0 0 3 3 3 0 TraC-like protein LIM PF00412.22 CBY40671.1 - 2.3 8.5 68.6 3.5 7.9 7.2 8.0 3 3 5 8 8 8 0 LIM domain Nucleos_tra2_C PF07662.13 CBY40673.1 - 1.3e-69 234.2 5.9 1.3e-69 234.2 5.9 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CBY40673.1 - 2.3e-19 69.7 2.5 2.3e-19 69.7 2.5 3.5 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CBY40673.1 - 2.7e-05 24.4 9.4 2.7e-05 24.4 9.4 3.8 4 0 0 4 4 4 1 Nucleoside recognition UPF0227 PF05728.12 CBY40673.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF3784 PF12650.7 CBY40673.1 - 0.024 14.8 2.2 0.024 14.8 2.2 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3784) DUF485 PF04341.12 CBY40673.1 - 0.37 10.8 0.1 0.37 10.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function, DUF485 BRI3BP PF14965.6 CBY40673.1 - 3.7 7.0 9.0 18 4.8 0.1 3.9 4 0 0 4 4 4 0 Negative regulator of p53/TP53 La PF05383.17 CBY40675.1 - 4.2e-14 52.3 0.1 1.1e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY40675.1 - 0.083 12.7 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADK PF00406.22 CBY40677.1 - 2.7e-16 60.0 0.7 3.7e-10 40.1 0.0 3.6 3 1 1 4 4 3 2 Adenylate kinase AAA_33 PF13671.6 CBY40677.1 - 7.7e-08 32.6 1.5 0.065 13.4 0.0 4.7 2 2 1 4 4 4 2 AAA domain AAA_17 PF13207.6 CBY40677.1 - 1.2e-07 32.2 0.3 0.04 14.4 0.0 3.7 2 2 2 4 4 3 2 AAA domain AAA_5 PF07728.14 CBY40677.1 - 1.2e-06 28.6 0.0 0.02 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBY40677.1 - 5e-06 27.1 1.3 0.17 12.4 0.0 3.6 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 CBY40677.1 - 1.4e-05 25.6 0.2 0.074 13.4 0.0 3.1 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBY40677.1 - 1.7e-05 25.2 0.0 0.0038 17.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY40677.1 - 4.4e-05 23.3 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBY40677.1 - 4.9e-05 22.8 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CBY40677.1 - 0.00041 20.5 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CBY40677.1 - 0.0024 18.2 0.0 0.57 10.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CBY40677.1 - 0.0033 17.2 0.2 0.3 10.8 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_28 PF13521.6 CBY40677.1 - 0.0058 16.9 0.0 0.085 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBY40677.1 - 0.0075 16.4 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CBY40677.1 - 0.0082 16.1 0.4 0.56 10.1 0.1 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CBY40677.1 - 0.013 16.1 0.3 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter DUF5582 PF17819.1 CBY40677.1 - 0.014 15.9 0.1 0.036 14.5 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5582) NB-ARC PF00931.22 CBY40677.1 - 0.019 14.2 0.0 0.084 12.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 CBY40677.1 - 0.021 14.9 0.9 14 5.7 0.0 3.6 4 0 0 4 4 4 0 Shikimate kinase AAA_7 PF12775.7 CBY40677.1 - 0.029 13.9 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CBY40677.1 - 0.03 13.4 0.0 0.07 12.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CBY40677.1 - 0.032 13.8 0.3 0.16 11.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 CBY40677.1 - 0.034 14.1 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 CBY40677.1 - 0.048 12.6 0.0 8.7 5.1 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain RuvB_N PF05496.12 CBY40677.1 - 0.053 13.3 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBY40677.1 - 0.057 13.8 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IPT PF01745.16 CBY40677.1 - 0.062 12.7 0.1 0.71 9.2 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase G-alpha PF00503.20 CBY40677.1 - 0.062 12.4 0.1 16 4.5 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 CBY40677.1 - 0.12 12.1 0.0 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain YmgB PF10798.8 CBY40680.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.0 2 1 0 2 2 2 0 Biofilm development protein YmgB/AriR DUF536 PF04394.14 CBY40681.1 - 0.03 14.2 3.2 5.6 6.9 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 LMSTEN PF07988.12 CBY40681.1 - 0.33 10.5 4.1 0.29 10.6 2.0 2.0 2 0 0 2 2 2 0 LMSTEN motif AKAP7_NLS PF10469.9 CBY40681.1 - 0.37 10.6 6.9 0.28 11.1 3.7 2.2 1 1 1 2 2 2 0 AKAP7 2'5' RNA ligase-like domain Phlebovirus_NSM PF07246.11 CBY40681.1 - 0.48 9.7 15.5 0.34 10.2 5.3 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Pox_F17 PF04767.12 CBY40682.1 - 1.4 9.5 6.3 1.8 9.1 3.0 2.8 2 1 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein DNA_pol_B_2 PF03175.13 CBY40683.1 - 5.3e-15 55.3 20.9 1.5e-08 33.9 5.0 3.3 2 1 1 3 3 3 3 DNA polymerase type B, organellar and viral Phage_TAC_5 PF08890.11 CBY40683.1 - 0.061 13.3 1.5 0.24 11.4 0.1 2.4 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC DHO_dh PF01180.21 CBY40684.1 - 8.4e-34 117.1 0.0 1.3e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 CBY40684.1 - 4.2e-23 81.2 12.3 1.1e-22 79.9 11.8 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 CBY40684.1 - 4.5e-09 36.0 0.1 1e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 CBY40684.1 - 3.4e-08 33.2 16.4 0.00011 22.2 2.4 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 CBY40684.1 - 1.4e-07 31.0 14.8 0.0018 18.0 3.4 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CBY40684.1 - 4e-07 29.7 14.3 0.0017 18.4 3.0 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CBY40684.1 - 1.4e-06 28.8 10.5 4.2e-06 27.3 10.5 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 CBY40684.1 - 7.7e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 CBY40684.1 - 5.7e-05 23.1 13.9 0.0004 20.4 12.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBY40684.1 - 0.00043 20.4 11.1 0.0011 19.1 11.1 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Dus PF01207.17 CBY40684.1 - 0.0031 16.6 0.2 0.02 14.0 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_13 PF13370.6 CBY40684.1 - 0.0043 17.6 15.3 0.32 11.6 3.9 2.9 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 CBY40684.1 - 0.0062 17.1 6.4 1.3 9.6 1.2 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBY40684.1 - 0.0077 16.7 14.2 0.093 13.3 2.8 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CBY40684.1 - 0.067 13.6 12.0 0.84 10.1 3.5 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 CBY40684.1 - 0.14 12.7 0.0 0.45 11.1 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_22 PF17179.4 CBY40684.1 - 0.16 12.8 8.9 4.1 8.3 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF3612 PF12268.8 CBY40685.1 - 0.091 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) DUF1943 PF09172.11 CBY40685.1 - 4.6 6.4 8.3 0.37 10.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) RNA_pol_Rpb6 PF01192.22 CBY40686.1 - 0.06 13.3 0.0 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb6 Ubie_methyltran PF01209.18 CBY40686.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Synaptobrevin PF00957.21 CBY40687.1 - 1.4e-27 95.3 1.6 2e-27 94.8 1.6 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF4134 PF13572.6 CBY40687.1 - 0.2 12.0 1.2 0.27 11.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Actin PF00022.19 CBY40688.1 - 5.5e-41 140.5 0.0 6e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Actin MOZ_SAS PF01853.18 CBY40689.1 - 9.2e-51 172.0 0.1 1.1e-50 171.8 0.1 1.0 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 CBY40689.1 - 0.00095 19.6 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY40689.1 - 0.18 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_C14 PF00656.22 CBY40690.1 - 2.9e-07 30.7 0.1 0.003 17.6 0.0 2.1 2 0 0 2 2 2 2 Caspase domain Lectin_C PF00059.21 CBY40692.1 - 1.1e-22 80.8 13.2 5.7e-16 59.2 4.8 2.8 2 0 0 2 2 2 2 Lectin C-type domain Trefoil PF00088.18 CBY40692.1 - 3e-10 39.8 8.9 3e-10 39.8 8.9 2.5 2 0 0 2 2 2 1 Trefoil (P-type) domain Podoplanin PF05808.11 CBY40692.1 - 0.0058 16.8 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 CBY40692.1 - 0.043 13.9 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) UCH PF00443.29 CBY40693.1 - 1.2e-17 64.2 0.1 1.5e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY40693.1 - 9e-08 32.1 0.6 1.6e-07 31.2 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Josephin PF02099.17 CBY40693.1 - 0.028 14.5 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Josephin Glyco_hydro_18 PF00704.28 CBY40695.1 - 9e-23 81.5 0.0 1.1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cyclin PF08613.11 CBY40696.1 - 9.5e-07 29.3 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBY40696.1 - 0.00044 20.0 0.1 0.00091 19.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2303 PF10065.9 CBY40696.1 - 0.091 11.9 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF2922 PF11148.8 CBY40696.1 - 0.1 12.3 0.1 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) YjcQ PF09639.10 CBY40697.1 - 0.0085 16.3 0.8 0.14 12.4 0.1 2.8 2 0 0 2 2 2 1 YjcQ protein DUF3231 PF11553.8 CBY40697.1 - 0.034 13.8 0.4 2.6 7.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) SprT-like PF10263.9 CBY40697.1 - 0.05 13.5 0.6 0.68 9.8 0.0 2.8 2 0 0 2 2 2 0 SprT-like family ChapFlgA PF13144.6 CBY40697.1 - 0.16 12.0 0.4 0.46 10.5 0.4 1.7 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Scramblase PF03803.15 CBY40698.1 - 6.7e-12 45.2 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Scramblase Mucin PF01456.17 CBY40699.1 - 0.08 12.9 18.5 0.14 12.2 18.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY40699.1 - 0.14 12.1 8.0 0.27 11.2 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) gag-asp_proteas PF13975.6 CBY40700.1 - 1.8e-06 28.4 0.0 4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCCH PF00642.24 CBY40700.1 - 1.6e-05 24.7 3.0 3.8e-05 23.5 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Asp_protease_2 PF13650.6 CBY40700.1 - 2.1e-05 25.1 0.0 4.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf_CCCH_4 PF18345.1 CBY40700.1 - 5.2e-05 23.2 4.1 0.00012 22.0 4.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBY40700.1 - 0.00098 18.9 3.5 0.0018 18.0 3.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBY40700.1 - 0.014 16.0 2.8 0.021 15.5 0.3 2.4 2 0 0 2 2 2 0 Torus domain RVP PF00077.20 CBY40700.1 - 0.036 14.4 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCCH_2 PF14608.6 CBY40700.1 - 1.5 9.4 4.1 0.74 10.4 1.4 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SYF2 PF08231.12 CBY40700.1 - 2.9 8.3 9.7 0.18 12.2 3.7 2.1 2 0 0 2 2 2 0 SYF2 splicing factor Zona_pellucida PF00100.23 CBY40701.1 - 1.3e-20 74.3 1.8 2.1e-20 73.6 1.6 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain DUF2970 PF11174.8 CBY40701.1 - 0.026 14.4 2.7 0.042 13.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Saf_2TM PF18303.1 CBY40701.1 - 0.083 12.5 0.5 0.13 11.9 0.5 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain ECH_1 PF00378.20 CBY40702.1 - 3.7e-34 118.2 0.0 4.3e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY40702.1 - 1.5e-15 57.5 0.0 1.9e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S41_N PF11918.8 CBY40702.1 - 0.037 14.3 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF1949 PF09186.11 CBY40702.1 - 0.17 11.8 0.2 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Arm PF00514.23 CBY40703.1 - 3e-66 217.6 10.7 1.2e-11 44.2 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBY40703.1 - 7.6e-21 73.4 0.5 2.1e-20 72.0 0.5 1.8 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 CBY40703.1 - 1.9e-18 66.7 2.9 5.7e-18 65.1 2.9 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 CBY40703.1 - 1.2e-13 51.2 0.1 3e-06 27.5 0.0 5.4 2 1 3 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 CBY40703.1 - 7.7e-11 42.3 4.9 0.0018 18.8 0.2 5.4 4 1 3 7 7 7 3 HEAT-like repeat HEAT PF02985.22 CBY40703.1 - 1.1e-07 31.5 0.1 0.65 10.4 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat DUF3385 PF11865.8 CBY40703.1 - 0.0024 17.8 0.1 0.029 14.3 0.0 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 CBY40703.1 - 0.0068 16.5 0.0 10 6.1 0.0 3.7 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 SEN1_N PF12726.7 CBY40703.1 - 0.0079 14.5 0.1 0.11 10.6 0.0 2.4 3 0 0 3 3 3 1 SEN1 N terminal V-ATPase_H_C PF11698.8 CBY40703.1 - 0.021 15.0 0.8 0.57 10.3 0.1 3.2 4 0 0 4 4 4 0 V-ATPase subunit H ParcG PF10274.9 CBY40703.1 - 0.17 12.0 0.2 2.9 8.0 0.0 2.9 3 1 0 3 3 3 0 Parkin co-regulated protein zf-C3HC4_3 PF13920.6 CBY40704.1 - 4.6e-11 42.4 12.7 6.6e-11 41.9 12.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY40704.1 - 0.00047 20.0 13.0 0.00076 19.3 13.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBY40704.1 - 0.00074 19.8 14.1 0.0014 18.9 14.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY40704.1 - 0.0024 17.7 16.6 0.0042 16.9 16.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY40704.1 - 0.13 12.2 15.7 0.26 11.3 15.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Chitin_synth_2 PF03142.15 CBY40705.1 - 6.8e-18 64.6 3.2 1.3e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 CBY40705.1 - 0.0037 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CBY40705.1 - 0.13 12.1 11.6 0.79 9.6 11.6 2.2 1 1 0 1 1 1 0 Glycosyl transferase family group 2 EGF PF00008.27 CBY40706.1 - 8.6e-05 22.8 4.6 0.00029 21.1 3.6 2.3 2 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CBY40706.1 - 0.021 15.5 3.7 0.021 15.5 3.7 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_2 PF07974.13 CBY40706.1 - 0.16 12.3 11.4 0.39 11.1 11.4 1.6 1 0 0 1 1 1 0 EGF-like domain TFIIA PF03153.13 CBY40707.1 - 0.61 10.0 19.8 0.74 9.7 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 CBY40707.1 - 8.9 6.8 28.3 13 6.3 28.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Chordopox_A13L PF05961.11 CBY40708.1 - 0.0097 16.1 0.2 0.02 15.1 0.2 1.5 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DAG1 PF05454.11 CBY40708.1 - 0.01 15.3 0.4 0.017 14.5 0.4 1.4 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Gram_pos_anchor PF00746.21 CBY40708.1 - 0.01 15.8 0.3 0.032 14.1 0.3 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF5316 PF17247.2 CBY40708.1 - 0.03 14.3 0.4 0.045 13.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5316) UPF0154 PF03672.13 CBY40709.1 - 0.053 13.6 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RhodobacterPufX PF11511.8 CBY40709.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Intrinsic membrane protein PufX G_glu_transpept PF01019.21 CBY40710.1 - 1e-64 219.2 0.0 1.1e-64 219.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase T-box PF00907.22 CBY40711.1 - 3.2e-76 255.7 0.1 3.2e-76 255.7 0.1 1.7 2 0 0 2 2 2 1 T-box DUF2057 PF09829.9 CBY40711.1 - 0.01 16.0 5.1 0.69 10.0 1.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Plectin PF00681.20 CBY40712.1 - 6.6e-36 121.9 0.6 3.6e-16 58.8 0.1 5.0 4 1 1 5 5 5 4 Plectin repeat Myosin_tail_1 PF01576.19 CBY40714.1 - 4.3e-132 442.1 228.1 4.8e-77 259.8 123.0 2.0 1 1 1 2 2 2 2 Myosin tail DUF4250 PF14056.6 CBY40714.1 - 0.02 14.8 0.3 0.02 14.8 0.3 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF4250) HSBP1 PF06825.12 CBY40714.1 - 5.3 7.0 24.6 0.3 11.0 0.4 6.9 7 1 1 8 8 8 0 Heat shock factor binding protein 1 Filament PF00038.21 CBY40714.1 - 9.4 5.7 193.7 0.37 10.3 52.2 6.5 1 1 4 5 5 5 0 Intermediate filament protein TB PF00683.17 CBY40715.1 - 9.4e-12 44.5 35.5 3.9e-07 29.7 8.4 4.2 3 0 0 3 3 3 3 TB domain EGF PF00008.27 CBY40715.1 - 0.0032 17.7 8.1 0.0032 17.7 8.1 4.9 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 CBY40715.1 - 0.0055 17.3 7.1 0.0055 17.3 7.1 5.5 5 0 0 5 5 5 2 Human growth factor-like EGF Chordopox_G2 PF05796.12 CBY40715.1 - 0.041 13.3 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 STN PF07660.14 CBY40715.1 - 0.22 11.3 0.0 0.76 9.6 0.0 1.8 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain Glyco_hydro_18 PF00704.28 CBY40717.1 - 3.8e-85 286.4 0.4 6.5e-85 285.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LPMO_10 PF03067.15 CBY40717.1 - 6.4e-30 105.3 1.8 7.4e-30 105.1 0.2 2.0 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 CBY40717.1 - 2.4e-24 85.2 29.8 8.5e-13 48.3 6.5 4.2 4 0 0 4 4 4 2 Chitin binding Peritrophin-A domain DAG_kinase_N PF14513.6 CBY40717.1 - 0.11 12.7 0.2 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus RAP1 PF07218.11 CBY40717.1 - 0.61 8.3 7.2 0.93 7.7 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PRR18 PF15671.5 CBY40717.1 - 1.6 8.6 10.6 0.035 14.0 3.5 1.8 2 0 0 2 2 2 0 Proline-rich protein family 18 Pkinase_Tyr PF07714.17 CBY40718.1 - 1.3e-66 224.6 0.0 1.8e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY40718.1 - 1.9e-38 132.3 0.0 2.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gla PF00594.20 CBY40718.1 - 3.4e-17 62.4 5.7 7.1e-17 61.3 5.7 1.6 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain TMEM100 PF16311.5 CBY40718.1 - 7.2e-05 22.4 0.2 0.00013 21.5 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 100 Haspin_kinase PF12330.8 CBY40718.1 - 0.018 14.0 0.1 0.033 13.2 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain LapA_dom PF06305.11 CBY40718.1 - 0.039 13.8 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Caskin-Pro-rich PF16907.5 CBY40718.1 - 0.044 14.3 1.6 0.1 13.1 1.6 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins BatD PF13584.6 CBY40718.1 - 0.049 12.4 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 CBY40718.1 - 0.063 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 CBY40718.1 - 0.069 14.0 0.1 0.069 14.0 0.1 2.4 3 1 0 3 3 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 CBY40718.1 - 0.077 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) 7tm_3 PF00003.22 CBY40718.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR ECSCR PF15820.5 CBY40718.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 CBY40718.1 - 0.61 10.0 2.5 2.4 8.0 2.3 2.0 1 1 0 1 1 1 0 TMEM154 protein family RabGAP-TBC PF00566.18 CBY40719.1 - 6.5e-37 127.3 0.6 9.2e-37 126.8 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBY40719.1 - 1.1e-10 41.9 0.0 2.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain ERAP1_C PF11838.8 CBY40719.1 - 0.05 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 ERAP1-like C-terminal domain MORN PF02493.20 CBY40722.1 - 3.3e-36 121.0 59.4 2e-06 27.3 1.7 8.9 8 0 0 8 8 8 8 MORN repeat Cas_Cas1 PF01867.16 CBY40722.1 - 0.42 9.7 2.5 0.63 9.1 2.5 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 DUF3619 PF12279.8 CBY40722.1 - 0.48 10.8 3.4 0.74 10.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4398 PF14346.6 CBY40722.1 - 2.1 9.0 15.1 1.4 9.6 8.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) adh_short PF00106.25 CBY40724.1 - 5.5e-52 176.1 0.4 6.2e-52 175.9 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY40724.1 - 2.9e-35 121.9 0.4 3.6e-35 121.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY40724.1 - 3.6e-11 43.3 0.3 4.7e-11 42.9 0.3 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBY40724.1 - 0.0003 20.2 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY40724.1 - 0.017 14.6 0.2 0.032 13.7 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family YccV-like PF08755.11 CBY40724.1 - 0.042 14.3 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like ATP-synt_F PF01990.17 CBY40725.1 - 0.21 11.9 2.0 0.45 10.9 0.4 2.2 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit PCB_OB PF17092.5 CBY40727.1 - 0.035 14.9 1.3 0.035 14.9 1.3 2.4 2 1 0 2 2 2 0 Penicillin-binding protein OB-like domain TrbC PF04956.13 CBY40728.1 - 0.012 15.8 3.0 0.012 15.8 3.0 1.8 2 0 0 2 2 2 0 TrbC/VIRB2 family Orf78 PF06024.12 CBY40728.1 - 8.4 6.8 9.6 13 6.1 0.9 2.1 1 1 1 2 2 2 0 Orf78 (ac78) 4PPT_N PF17837.1 CBY40729.1 - 0.065 13.4 0.8 0.1 12.8 0.4 1.6 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain VWD PF00094.25 CBY40730.1 - 1.4e-46 158.6 21.2 1.2e-15 58.1 1.3 3.5 3 0 0 3 3 3 3 von Willebrand factor type D domain C8 PF08742.11 CBY40730.1 - 3.3e-19 69.1 28.2 2.1e-08 34.5 7.0 6.8 7 0 0 7 7 7 3 C8 domain TIL PF01826.17 CBY40730.1 - 3.8e-11 43.0 46.2 1.4e-06 28.4 10.3 10.2 10 2 0 10 10 10 4 Trypsin Inhibitor like cysteine rich domain MobA_MobL PF03389.15 CBY40730.1 - 0.012 15.3 0.1 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 MobA/MobL family C1q PF00386.21 CBY40731.1 - 3.2e-12 46.7 0.3 5.7e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 C1q domain Collagen PF01391.18 CBY40731.1 - 0.043 13.6 3.4 0.076 12.8 3.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) LRR_8 PF13855.6 CBY40732.1 - 9.7e-05 22.1 1.9 0.00018 21.2 1.1 1.8 1 1 1 2 2 2 1 Leucine rich repeat LRR_5 PF13306.6 CBY40732.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 CBY40732.1 - 0.4 11.2 9.4 11 6.6 3.2 3.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) SHNi-TPR PF10516.9 CBY40735.1 - 0.13 11.7 2.0 8.4 5.9 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR FUSC PF04632.12 CBY40735.1 - 4.1 5.8 7.1 0.48 8.9 0.9 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family La PF05383.17 CBY40736.1 - 2.5e-05 24.3 0.0 6.5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY40736.1 - 0.034 13.9 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HR_lesion PF05514.11 CBY40736.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 HR-like lesion-inducing DUF2870 PF11069.8 CBY40737.1 - 5.6e-41 138.8 1.7 1.1e-40 137.8 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Cep57_CLD PF14073.6 CBY40738.1 - 3.2e-10 40.3 14.7 3.2e-10 40.3 14.7 3.6 3 2 0 3 3 3 1 Centrosome localisation domain of Cep57 ING PF12998.7 CBY40738.1 - 4.6 7.9 18.8 0.17 12.5 2.9 3.2 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Ras PF00071.22 CBY40739.1 - 2.2e-20 72.9 0.0 2.5e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY40739.1 - 3.6e-10 40.1 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBY40739.1 - 7e-06 26.1 0.0 8.5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBY40739.1 - 0.00029 20.3 0.0 0.00032 20.1 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CBY40739.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 CBY40739.1 - 0.0022 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 CBY40739.1 - 0.0025 17.9 0.0 0.0082 16.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 CBY40739.1 - 0.012 15.1 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Orbi_NS3 PF01616.16 CBY40739.1 - 0.053 13.2 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Orbivirus NS3 AAA_14 PF13173.6 CBY40739.1 - 0.061 13.4 0.0 0.11 12.5 0.0 1.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBY40739.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Cullin PF00888.22 CBY40740.1 - 1e-108 364.6 14.5 1.3e-108 364.2 14.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY40740.1 - 5.6e-13 48.7 0.3 1.7e-12 47.2 0.1 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain ANAPC4_WD40 PF12894.7 CBY40742.1 - 5.9e-05 23.3 0.0 0.24 11.7 0.0 3.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY40742.1 - 0.00049 20.8 8.1 0.037 14.9 0.3 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat HMG_box PF00505.19 CBY40743.1 - 1.1e-22 80.2 3.9 2.2e-22 79.2 3.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY40743.1 - 3.6e-08 33.9 5.4 8.2e-08 32.7 5.4 1.6 1 0 0 1 1 1 1 HMG-box domain NINJA_B PF16136.5 CBY40743.1 - 0.0056 17.0 1.8 0.0099 16.2 1.8 1.4 1 0 0 1 1 1 1 Putative nuclear localisation signal DUF4263 PF14082.6 CBY40743.1 - 0.1 12.8 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Ribonuc_red_sm PF00268.21 CBY40745.1 - 1.6e-115 385.4 2.0 2.5e-115 384.8 2.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain CCDC-167 PF15188.6 CBY40745.1 - 0.0075 16.6 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Polo_box_3 PF18544.1 CBY40745.1 - 0.087 13.5 1.4 0.22 12.2 0.1 2.4 3 0 0 3 3 3 0 Polo box domain Chromo PF00385.24 CBY40746.1 - 4.6e-16 58.5 3.3 6.7e-16 57.9 0.5 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CBY40746.1 - 1.2e-12 47.8 4.4 6.7e-11 42.1 1.1 2.5 2 0 0 2 2 2 2 Chromo shadow domain Tudor-knot PF11717.8 CBY40746.1 - 0.038 13.9 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 CBY40746.1 - 0.082 13.1 0.9 0.39 10.9 0.2 2.2 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 CDK2AP PF09806.9 CBY40747.1 - 6.6e-20 72.2 3.0 8.1e-20 71.9 3.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein PRKG1_interact PF15898.5 CBY40747.1 - 0.00042 21.2 6.8 0.59 11.1 0.0 2.2 2 0 0 2 2 2 2 cGMP-dependent protein kinase interacting domain AIP3 PF03915.13 CBY40747.1 - 0.0021 17.2 3.5 0.0028 16.8 3.5 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1887 PF09002.11 CBY40747.1 - 0.0025 16.6 1.1 0.0029 16.3 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF3365 PF11845.8 CBY40747.1 - 0.0058 17.0 3.6 0.0067 16.8 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) Striatin PF08232.12 CBY40747.1 - 0.016 15.8 8.3 0.021 15.4 8.3 1.1 1 0 0 1 1 1 0 Striatin family DUF2452 PF10504.9 CBY40747.1 - 0.094 12.2 2.8 0.15 11.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) MBR1 PF17058.5 CBY40747.1 - 0.12 12.7 3.2 0.15 12.3 3.2 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 CDC37_N PF03234.14 CBY40747.1 - 0.13 13.2 3.3 0.19 12.6 3.3 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF2203 PF09969.9 CBY40747.1 - 1.8 9.3 6.1 1.6 9.5 4.2 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Presenilin PF01080.17 CBY40747.1 - 2.1 7.0 4.2 2.1 7.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin Cdh1_DBD_1 PF18196.1 CBY40747.1 - 4.5 7.6 9.0 4.9 7.5 8.0 1.6 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Toxin_34 PF08396.10 CBY40750.1 - 0.022 15.5 0.1 0.027 15.2 0.1 1.2 1 0 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family Cytochrom_C1 PF02167.15 CBY40751.1 - 5.8e-06 26.2 0.0 6.4e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Myosin_tail_1 PF01576.19 CBY40753.1 - 1.5e-88 297.9 139.8 1.7e-88 297.7 139.8 1.0 1 0 0 1 1 1 1 Myosin tail Sec2p PF06428.11 CBY40753.1 - 0.0051 16.7 7.9 0.0051 16.7 7.9 10.9 2 2 9 11 11 11 2 GDP/GTP exchange factor Sec2p TSNAXIP1_N PF15739.5 CBY40753.1 - 0.015 15.6 5.3 0.015 15.6 5.3 9.1 3 2 5 9 9 9 0 Translin-associated factor X-interacting N-terminus SAB PF04382.13 CBY40753.1 - 0.074 13.1 8.1 0.35 11.0 0.5 3.6 2 0 0 2 2 2 0 SAB domain SpoIIID PF12116.8 CBY40753.1 - 9.8 6.4 12.8 1.4 9.1 0.1 5.0 4 2 2 6 6 6 0 Stage III sporulation protein D Myosin_tail_1 PF01576.19 CBY40754.1 - 6e-12 44.3 19.2 6.5e-12 44.2 19.2 1.0 1 0 0 1 1 1 1 Myosin tail FAM184 PF15665.5 CBY40754.1 - 0.18 11.6 15.7 0.4 10.4 15.7 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Tektin PF03148.14 CBY40754.1 - 0.2 10.4 22.8 0.35 9.6 10.3 2.0 1 1 1 2 2 2 0 Tektin family DUF745 PF05335.13 CBY40754.1 - 0.27 10.9 9.9 0.33 10.7 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PEP-utilisers_N PF05524.13 CBY40754.1 - 0.38 11.0 2.9 0.35 11.1 1.0 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal eIF-4B PF06273.11 CBY40754.1 - 0.55 9.2 7.8 0.7 8.9 7.8 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Spc7 PF08317.11 CBY40754.1 - 0.64 8.8 15.7 0.85 8.4 15.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 CBY40754.1 - 0.64 10.3 3.7 0.45 10.8 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CBY40754.1 - 0.75 9.8 7.2 1.4 8.9 7.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CBY40754.1 - 0.94 8.7 8.5 1.1 8.4 8.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2524 PF10732.9 CBY40754.1 - 1.6 9.1 11.3 0.22 11.9 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Exonuc_VII_L PF02601.15 CBY40754.1 - 3.3 7.2 8.7 4 6.9 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_2 PF07716.15 CBY40754.1 - 4.3 7.5 17.5 6.5 6.9 3.9 3.8 2 2 1 3 3 3 0 Basic region leucine zipper Cauli_AT PF03233.13 CBY40754.1 - 4.7 7.1 10.0 2.9 7.8 5.2 2.0 1 1 1 2 2 2 0 Aphid transmission protein DUF4407 PF14362.6 CBY40754.1 - 5.1 6.3 9.4 6.6 6.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_15 PF00723.21 CBY40755.1 - 3.7e-37 128.2 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Med24_N PF11277.8 CBY40756.1 - 5.3e-39 134.1 13.9 4.4e-31 107.8 5.1 2.5 3 0 0 3 3 3 2 Mediator complex subunit 24 N-terminal Sulfotransfer_2 PF03567.14 CBY40757.1 - 2.2e-27 96.6 0.0 2.7e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase family SOBP PF15279.6 CBY40758.1 - 0.16 12.5 18.4 0.23 12.0 18.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein YabA PF06156.13 CBY40760.1 - 0.0033 18.0 0.8 0.0033 18.0 0.8 2.1 2 0 0 2 2 2 1 Initiation control protein YabA MAP7 PF05672.11 CBY40760.1 - 0.031 14.0 23.8 0.042 13.5 23.8 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Peptidase_C10 PF01640.17 CBY40760.1 - 0.25 11.6 4.8 0.3 11.4 4.8 1.1 1 0 0 1 1 1 0 Peptidase C10 family K_trans PF02705.16 CBY40760.1 - 0.95 7.9 3.3 1.1 7.7 3.3 1.1 1 0 0 1 1 1 0 K+ potassium transporter CDK5_activator PF03261.15 CBY40760.1 - 2.5 7.5 11.6 3.3 7.2 11.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NRBF2 PF08961.10 CBY40760.1 - 2.7 7.5 15.1 13 5.3 15.0 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Arc_PepC_II PF06847.11 CBY40760.1 - 4.8 7.8 6.7 2.3 8.8 0.3 2.3 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II GIT_CC PF16559.5 CBY40761.1 - 2.6 8.0 10.1 2.4 8.1 4.6 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Glyco_transf_10 PF00852.19 CBY40763.1 - 7.1e-53 178.9 0.0 1.1e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY40763.1 - 2.2e-08 34.5 0.1 0.001 19.5 0.0 3.2 2 1 1 3 3 3 2 Fucosyltransferase, N-terminal Fer4_20 PF14691.6 CBY40764.1 - 3.3e-33 113.8 0.9 5.2e-33 113.2 0.9 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CBY40764.1 - 1e-05 25.7 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY40764.1 - 0.0054 16.0 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBY40764.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 CBY40764.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Chibby PF14645.6 CBY40765.1 - 5.4e-23 81.6 2.0 6.6e-23 81.3 2.0 1.1 1 0 0 1 1 1 1 Chibby family FhuF PF06276.12 CBY40766.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Baculo_p74_N PF08404.10 CBY40767.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Carn_acyltransf PF00755.20 CBY40768.1 - 5.1e-79 266.5 1.1 4.5e-78 263.4 1.1 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Sugar_tr PF00083.24 CBY40769.1 - 7.2e-26 91.1 13.8 9.8e-26 90.6 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY40769.1 - 2.1e-16 59.8 53.5 7.9e-15 54.6 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBY40769.1 - 0.003 16.5 5.0 0.003 16.5 5.0 2.2 2 0 0 2 2 2 1 MFS_1 like family Gram_pos_anchor PF00746.21 CBY40769.1 - 0.054 13.4 7.8 2.8 8.0 1.2 3.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF2231 PF09990.9 CBY40769.1 - 0.45 11.0 7.0 0.11 12.9 1.5 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Carn_acyltransf PF00755.20 CBY40770.1 - 4.6e-24 85.0 0.4 5.7e-24 84.7 0.4 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CUB PF00431.20 CBY40771.1 - 3.3e-21 75.7 0.0 5.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 CUB domain SARAF PF06682.12 CBY40771.1 - 0.054 13.1 1.4 0.095 12.3 0.0 1.9 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FliX PF10768.9 CBY40771.1 - 0.23 12.0 3.3 0.4 11.2 3.3 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator SLC12 PF03522.15 CBY40773.1 - 4.4e-12 45.8 0.2 7.7e-12 44.9 0.2 1.5 1 1 0 1 1 1 1 Solute carrier family 12 zf-C2H2_4 PF13894.6 CBY40773.1 - 0.0075 17.0 0.3 0.035 14.9 0.3 2.3 1 0 0 1 1 1 1 C2H2-type zinc finger PilM_2 PF11104.8 CBY40773.1 - 0.016 14.2 0.2 0.026 13.6 0.2 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; zf-C2H2 PF00096.26 CBY40773.1 - 0.02 15.3 0.2 0.02 15.3 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY40773.1 - 0.028 14.2 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Methyltrans_RNA PF04452.14 CBY40773.1 - 0.12 11.6 0.6 10 5.4 0.1 2.2 2 0 0 2 2 2 0 RNA methyltransferase EF-hand_4 PF12763.7 CBY40775.1 - 4.6e-12 45.8 0.1 2.2e-11 43.6 0.0 2.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY40775.1 - 0.0051 16.3 0.0 0.022 14.3 0.0 2.2 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY40775.1 - 0.0067 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Cep57_CLD_2 PF14197.6 CBY40775.1 - 0.014 15.5 3.9 0.035 14.2 3.9 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 CBY40775.1 - 0.089 13.2 3.6 0.25 11.8 3.6 1.8 1 0 0 1 1 1 0 Cell division protein ZapB EF-hand_5 PF13202.6 CBY40775.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 EF hand I-set PF07679.16 CBY40776.1 - 1.2e-40 137.4 1.3 7.4e-09 35.6 0.5 7.1 7 0 0 7 7 7 6 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY40776.1 - 9.4e-26 90.2 1.0 3.3e-05 24.4 0.0 6.7 7 0 0 7 7 7 4 Immunoglobulin domain Ig_2 PF13895.6 CBY40776.1 - 1.4e-10 41.3 0.3 0.011 16.1 0.1 4.7 3 1 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 CBY40776.1 - 1.1e-06 28.8 1.3 0.79 9.9 0.0 5.6 6 1 0 6 6 6 2 Immunoglobulin domain V-set PF07686.17 CBY40776.1 - 1.6e-06 28.3 1.7 0.24 11.6 0.4 5.9 4 2 0 4 4 4 1 Immunoglobulin V-set domain BiPBP_C PF06832.12 CBY40776.1 - 1.3e-05 25.1 0.0 16 5.6 0.0 5.8 6 0 0 6 6 6 1 Penicillin-Binding Protein C-terminus Family fn3 PF00041.21 CBY40776.1 - 1.9e-05 24.9 0.0 0.00044 20.5 0.0 3.1 3 0 0 3 3 3 1 Fibronectin type III domain Izumo-Ig PF16706.5 CBY40776.1 - 0.025 14.6 0.3 0.93 9.6 0.0 3.2 3 0 0 3 3 3 0 Izumo-like Immunoglobulin domain SNF2_N PF00176.23 CBY40778.1 - 5.5e-50 170.0 1.0 1e-49 169.2 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBY40778.1 - 1.1e-20 74.0 0.1 5.1e-20 71.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY40778.1 - 0.0035 17.1 0.4 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY40778.1 - 0.007 16.4 0.0 0.03 14.3 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY40778.1 - 0.013 14.7 0.1 0.047 12.9 0.1 1.9 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 CBY40778.1 - 0.014 15.0 0.0 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 CBY40778.1 - 0.27 11.3 1.7 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain CRAL_TRIO_2 PF13716.6 CBY40779.1 - 2.1e-34 118.6 0.4 4.5e-34 117.6 0.4 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CBY40779.1 - 1.4e-14 54.2 1.3 3.3e-14 52.9 1.3 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain RhoGAP PF00620.27 CBY40779.1 - 1.6e-11 44.3 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF2067 PF09840.9 CBY40779.1 - 0.066 12.8 0.1 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) YvbH_ext PF11724.8 CBY40779.1 - 0.11 12.8 0.3 0.46 10.8 0.3 2.1 1 1 0 1 1 1 0 YvbH-like oligomerisation region RNase_T PF00929.24 CBY40780.1 - 8.2e-05 23.2 0.0 0.00031 21.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease Acetyltransf_1 PF00583.25 CBY40781.1 - 1.5e-15 57.5 0.0 2.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY40781.1 - 3.2e-10 40.3 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY40781.1 - 4.9e-08 33.0 0.1 8.8e-08 32.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY40781.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBY40781.1 - 0.00062 19.8 0.0 0.0033 17.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBY40781.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 CBY40781.1 - 0.00099 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CBY40781.1 - 0.0067 17.1 0.0 0.013 16.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBY40781.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CBY40781.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Phospholip_A2_1 PF00068.19 CBY40782.1 - 2.3e-12 47.4 6.5 2.3e-12 47.4 6.5 1.6 2 0 0 2 2 2 1 Phospholipase A2 UPF0184 PF03670.13 CBY40782.1 - 0.067 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Ion_trans PF00520.31 CBY40783.1 - 1.2e-05 24.6 6.7 2.5e-05 23.7 6.7 1.5 1 0 0 1 1 1 1 Ion transport protein DUF2198 PF09964.9 CBY40783.1 - 0.036 14.1 2.0 0.065 13.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) MbeB_N PF04837.12 CBY40783.1 - 0.063 13.6 0.3 0.26 11.6 0.3 2.0 1 0 0 1 1 1 0 MbeB-like, N-term conserved region EXS PF03124.14 CBY40785.1 - 4.3e-81 272.8 24.7 4.3e-81 272.8 24.7 1.8 1 1 1 2 2 2 1 EXS family SPX PF03105.19 CBY40785.1 - 2e-13 51.0 4.5 3.4e-13 50.3 4.5 1.3 1 0 0 1 1 1 1 SPX domain NPA PF16469.5 CBY40786.1 - 0.042 14.4 2.6 0.11 13.1 0.1 2.3 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 Peptidase_C78 PF07910.13 CBY40789.1 - 2.7e-36 125.0 0.1 3.5e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBY40789.1 - 0.0069 15.8 4.3 2.6 7.4 1.4 3.0 1 1 2 3 3 3 3 Peptidase family C54 Leo1 PF04004.13 CBY40790.1 - 4.3e-47 160.0 1.2 7.4e-47 159.3 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Meckelin PF09773.9 CBY40791.1 - 5e-90 302.8 5.4 5.5e-90 302.6 5.4 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Sulfotransfer_1 PF00685.27 CBY40792.1 - 1.3e-06 28.1 0.1 3.8e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY40792.1 - 5.6e-05 23.6 0.1 0.065 13.6 0.0 3.0 2 1 1 3 3 3 2 Sulfotransferase family Costars PF14705.6 CBY40794.1 - 7.9e-26 90.0 0.2 1.1e-25 89.6 0.2 1.2 1 0 0 1 1 1 1 Costars Methyltranf_PUA PF13636.6 CBY40794.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF FCH PF00611.23 CBY40798.1 - 1.5e-10 41.2 3.9 1.5e-10 41.2 0.3 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cor1 PF04803.12 CBY40798.1 - 0.0047 17.1 5.9 0.014 15.6 1.2 3.2 2 2 1 3 3 3 1 Cor1/Xlr/Xmr conserved region BRE1 PF08647.11 CBY40798.1 - 0.014 15.5 2.6 0.014 15.5 2.6 3.4 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase HCMV_UL139 PF12507.8 CBY40798.1 - 0.057 13.8 1.4 0.3 11.5 0.2 2.8 2 2 1 3 3 3 0 Human Cytomegalovirus UL139 protein CtIP_N PF10482.9 CBY40798.1 - 0.33 11.0 4.0 3.5 7.7 1.1 2.7 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF5385 PF17359.2 CBY40800.1 - 0.026 14.1 1.3 0.049 13.2 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Lipoprotein_18 PF06804.11 CBY40800.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Baculo_11_kDa PF06143.11 CBY40800.1 - 0.039 13.5 0.6 0.073 12.7 0.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family FeoB_associated PF12669.7 CBY40800.1 - 0.044 14.2 3.2 0.11 13.0 3.2 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein PTPLA PF04387.14 CBY40800.1 - 0.045 13.5 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA DUF5305 PF17231.2 CBY40800.1 - 0.06 12.7 1.4 0.076 12.4 0.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) AA_permease_2 PF13520.6 CBY40800.1 - 0.084 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease EphA2_TM PF14575.6 CBY40800.1 - 0.09 13.7 0.2 0.19 12.6 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 CBY40800.1 - 0.12 12.6 3.8 0.069 13.4 1.8 1.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator SIT PF15330.6 CBY40800.1 - 4.3 7.8 8.4 1.9 9.0 4.7 2.3 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT PIP5K PF01504.18 CBY40801.1 - 1.8e-64 217.6 4.4 1.8e-64 217.6 4.4 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Filament PF00038.21 CBY40802.1 - 2.1e-32 112.9 17.6 2.5e-32 112.7 17.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 CBY40802.1 - 0.00019 20.4 7.5 0.00024 20.1 7.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 CBY40802.1 - 0.00053 19.4 11.2 0.00067 19.1 11.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 CBY40802.1 - 0.0016 18.2 3.3 0.0036 17.1 3.3 1.6 1 1 0 1 1 1 1 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 CBY40802.1 - 0.0019 18.2 8.9 0.005 16.9 8.8 1.8 1 1 0 1 1 1 1 TolA binding protein trimerisation MscS_porin PF12795.7 CBY40802.1 - 0.0026 17.3 3.3 0.0035 16.9 3.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Rab5-bind PF09311.11 CBY40802.1 - 0.0037 16.7 7.6 0.0057 16.1 7.6 1.3 1 0 0 1 1 1 1 Rabaptin-like protein Golgin_A5 PF09787.9 CBY40802.1 - 0.0062 16.0 11.4 0.0091 15.5 11.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 V_ATPase_I PF01496.19 CBY40802.1 - 0.0064 14.5 2.6 0.0085 14.1 2.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TACC_C PF05010.14 CBY40802.1 - 0.0085 15.9 11.1 0.012 15.4 11.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 CBY40802.1 - 0.009 16.0 14.0 0.018 15.1 11.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 CBY40802.1 - 0.015 15.4 8.4 0.015 15.4 8.4 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FAM184 PF15665.5 CBY40802.1 - 0.029 14.2 11.2 0.038 13.8 11.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Prefoldin PF02996.17 CBY40802.1 - 0.035 14.0 7.9 0.059 13.3 1.4 2.8 1 1 1 2 2 2 0 Prefoldin subunit WEMBL PF05701.11 CBY40802.1 - 0.036 12.8 11.3 0.076 11.7 2.1 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light MAD PF05557.13 CBY40802.1 - 0.04 12.3 12.9 0.054 11.9 12.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.15 CBY40802.1 - 0.053 13.3 1.3 0.053 13.3 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator Tektin PF03148.14 CBY40802.1 - 0.058 12.1 11.8 0.086 11.6 11.8 1.2 1 0 0 1 1 1 0 Tektin family KASH_CCD PF14662.6 CBY40802.1 - 0.065 13.1 14.8 0.33 10.8 14.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CtIP_N PF10482.9 CBY40802.1 - 0.088 12.9 11.5 0.73 9.9 3.8 2.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TPR_MLP1_2 PF07926.12 CBY40802.1 - 0.092 12.8 12.4 0.17 11.9 9.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HemX PF04375.14 CBY40802.1 - 0.094 12.0 5.8 0.3 10.3 5.8 1.8 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF724 PF05266.14 CBY40802.1 - 0.095 12.5 11.3 0.11 12.3 10.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 CBY40802.1 - 0.095 13.3 7.5 0.23 12.1 4.2 2.8 1 1 2 3 3 2 0 SlyX DUF4456 PF14644.6 CBY40802.1 - 0.12 12.1 7.4 0.18 11.4 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) DUF2730 PF10805.8 CBY40802.1 - 0.13 12.3 5.6 0.2 11.8 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 CBY40802.1 - 0.14 12.5 9.3 0.09 13.1 3.6 2.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 CBY40802.1 - 0.14 12.8 11.2 1.1 10.0 5.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 CBY40802.1 - 0.14 11.4 11.1 0.23 10.7 8.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4201 PF13870.6 CBY40802.1 - 0.15 11.8 11.7 0.21 11.3 11.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 CBY40802.1 - 0.15 10.9 4.1 0.18 10.7 4.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 CBY40802.1 - 0.17 10.7 10.4 0.25 10.2 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) APG6_N PF17675.1 CBY40802.1 - 0.17 12.4 16.8 6.2 7.4 16.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 CBY40802.1 - 0.17 11.9 12.0 1.3 9.2 2.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 CBY40802.1 - 0.19 11.9 15.2 0.084 13.1 10.3 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Prominin PF05478.11 CBY40802.1 - 0.21 9.5 3.3 0.27 9.2 3.3 1.1 1 0 0 1 1 1 0 Prominin IMUP PF15761.5 CBY40802.1 - 0.3 11.8 12.9 2.1 9.1 7.8 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4407 PF14362.6 CBY40802.1 - 0.38 10.1 4.0 1.9 7.7 4.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 CBY40802.1 - 0.4 10.8 15.8 1 9.5 15.6 1.8 1 1 1 2 2 2 0 Tropomyosin like YlqD PF11068.8 CBY40802.1 - 0.54 10.6 6.8 1.5 9.2 6.8 1.7 1 1 0 1 1 1 0 YlqD protein HalX PF08663.10 CBY40802.1 - 0.58 10.5 10.8 0.5 10.7 4.8 2.9 2 1 1 3 3 2 0 HalX domain ABC_tran_CTD PF16326.5 CBY40802.1 - 0.6 10.4 10.1 5.6 7.3 8.2 2.7 1 1 1 2 2 1 0 ABC transporter C-terminal domain ERM PF00769.19 CBY40802.1 - 0.6 9.9 17.8 0.91 9.3 17.8 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FapA PF03961.13 CBY40802.1 - 0.64 8.6 5.8 0.93 8.0 5.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 CBY40802.1 - 0.66 10.1 13.7 2.2 8.4 13.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 CBY40802.1 - 0.72 10.3 11.7 0.15 12.5 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 CBY40802.1 - 0.73 9.3 6.6 0.92 9.0 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Poty_PP PF08440.10 CBY40802.1 - 0.78 8.8 5.6 3.3 6.7 3.7 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein TMF_TATA_bd PF12325.8 CBY40802.1 - 0.92 9.7 14.4 1.2 9.4 13.7 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CBY40802.1 - 0.94 9.5 5.3 1.4 8.9 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_20 PF13942.6 CBY40802.1 - 1.1 9.2 9.4 0.55 10.1 2.6 2.1 1 1 1 2 2 2 0 YfhG lipoprotein CLZ PF16526.5 CBY40802.1 - 1.2 9.6 8.0 5 7.5 0.8 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 CBY40802.1 - 1.2 8.4 7.7 1.6 7.9 7.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fez1 PF06818.15 CBY40802.1 - 1.2 9.5 14.1 2.6 8.4 3.3 2.0 1 1 1 2 2 2 0 Fez1 Tho2 PF11262.8 CBY40802.1 - 1.3 8.2 6.8 1.5 7.9 6.3 1.4 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HIP1_clath_bdg PF16515.5 CBY40802.1 - 1.5 9.5 13.4 1.7 9.3 6.8 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2203 PF09969.9 CBY40802.1 - 1.6 9.5 5.1 4.2 8.1 4.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fmp27_WPPW PF10359.9 CBY40802.1 - 1.6 7.5 14.6 0.026 13.4 6.8 1.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain GrpE PF01025.19 CBY40802.1 - 1.7 8.2 12.2 56 3.3 12.2 2.2 1 1 0 1 1 1 0 GrpE Cep57_CLD_2 PF14197.6 CBY40802.1 - 1.8 8.7 16.5 0.59 10.3 3.1 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DHR10 PF18595.1 CBY40802.1 - 1.9 8.6 13.2 2.6 8.1 12.3 1.7 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 CBY40802.1 - 1.9 8.7 11.1 2.8 8.1 4.5 2.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Swi5 PF07061.11 CBY40802.1 - 2.2 8.5 6.6 7.9 6.6 1.5 2.9 1 1 2 3 3 3 0 Swi5 KLRAQ PF10205.9 CBY40802.1 - 2.5 8.4 10.5 65 3.9 10.5 2.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Prefoldin_2 PF01920.20 CBY40802.1 - 2.7 8.0 13.7 3 7.8 0.5 2.9 1 1 3 4 4 4 0 Prefoldin subunit YscO-like PF16789.5 CBY40802.1 - 2.7 8.0 13.8 10 6.1 13.8 1.8 1 1 0 1 1 1 0 YscO-like protein DUF1640 PF07798.11 CBY40802.1 - 2.9 7.9 12.2 43 4.1 12.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) HR1 PF02185.16 CBY40802.1 - 2.9 8.1 11.5 0.12 12.5 3.5 2.5 2 1 1 3 3 2 0 Hr1 repeat FlaC_arch PF05377.11 CBY40802.1 - 3.1 8.2 10.9 0.71 10.3 0.4 3.4 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.13 CBY40802.1 - 3.3 7.6 9.5 1.2 9.0 4.4 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Tup_N PF08581.10 CBY40802.1 - 3.5 8.0 14.0 1.4 9.3 8.9 2.6 1 1 1 2 2 2 0 Tup N-terminal IFT20 PF14931.6 CBY40802.1 - 3.7 7.7 12.8 4.2 7.6 4.6 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Occludin_ELL PF07303.13 CBY40802.1 - 4.2 8.1 10.9 20 6.0 9.8 2.2 1 1 1 2 2 2 0 Occludin homology domain Pox_A_type_inc PF04508.12 CBY40802.1 - 4.4 7.3 9.3 17 5.4 0.0 4.0 5 0 0 5 5 3 0 Viral A-type inclusion protein repeat Spc24 PF08286.11 CBY40802.1 - 4.6 7.5 14.0 2.9 8.2 7.7 3.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DMPK_coil PF08826.10 CBY40802.1 - 4.7 7.4 15.2 0.81 9.8 2.3 2.8 2 1 1 3 3 2 0 DMPK coiled coil domain like Pepsin-I3 PF06394.13 CBY40802.1 - 4.8 7.5 7.4 7.7 6.8 0.9 2.5 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain TMF_DNA_bd PF12329.8 CBY40802.1 - 5.1 7.2 15.1 5.6 7.0 0.6 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 CBY40802.1 - 5.6 7.2 8.3 9.7 6.4 3.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 CBY40802.1 - 6.9 5.7 10.3 12 4.9 9.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 CBY40802.1 - 7 7.0 9.7 28 5.0 9.7 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4692 PF15763.5 CBY40802.1 - 7.2 7.1 18.6 1.3 9.5 7.6 2.5 2 1 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) GTP-bdg_M PF16360.5 CBY40802.1 - 8 7.1 7.6 1.6 9.4 2.2 2.4 2 1 1 3 3 2 0 GTP-binding GTPase Middle Region TSP_1 PF00090.19 CBY40803.1 - 0.0024 18.1 13.0 0.0024 18.1 13.0 2.6 2 1 0 2 2 2 1 Thrombospondin type 1 domain Kelch_1 PF01344.25 CBY40804.1 - 3.4e-23 81.0 1.0 1e-08 34.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBY40804.1 - 9.9e-21 73.3 2.6 1.5e-05 25.1 0.0 6.0 3 2 3 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CBY40804.1 - 3.3e-14 52.2 0.1 0.00062 19.6 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBY40804.1 - 2.8e-11 43.2 5.1 0.00099 19.1 0.0 5.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY40804.1 - 1e-08 35.2 2.1 0.047 14.0 0.0 6.4 6 2 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY40804.1 - 1.1e-06 28.4 1.8 3.8 7.6 0.0 5.6 6 0 0 6 6 6 2 Kelch motif DUF2963 PF11178.8 CBY40804.1 - 0.02 14.6 0.1 0.079 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Pkinase PF00069.25 CBY40806.1 - 1.2e-51 175.6 0.0 1.5e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40806.1 - 1.6e-28 99.7 0.0 2.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY40806.1 - 4.9e-05 22.4 0.0 0.002 17.1 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBY40806.1 - 0.00092 18.6 0.2 0.0034 16.8 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY40806.1 - 0.001 19.0 0.1 0.0019 18.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY40806.1 - 0.0056 16.0 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBY40806.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4990 PF16380.5 CBY40806.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function ATP-grasp_2 PF08442.10 CBY40807.1 - 2.3e-69 233.0 0.0 3.7e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBY40807.1 - 1.3e-26 93.3 0.8 2.3e-26 92.5 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CBY40807.1 - 1.9e-11 43.9 0.0 3.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CBY40807.1 - 5.6e-06 26.3 0.0 9.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 CBY40807.1 - 0.08 13.2 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain ER_lumen_recept PF00810.18 CBY40808.1 - 3.5e-54 183.6 8.0 3.5e-54 183.6 8.0 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY40808.1 - 0.029 14.1 13.0 0.19 11.5 0.3 3.1 4 0 0 4 4 4 0 PQ loop repeat ASC PF00858.24 CBY40809.1 - 5.2e-10 38.9 0.0 7.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel Rhomboid PF01694.22 CBY40810.1 - 3.4e-05 23.9 0.9 6.4e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 Rhomboid family OapA_N PF08525.11 CBY40810.1 - 0.01 15.8 1.1 0.019 14.9 1.1 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF3810 PF12725.7 CBY40810.1 - 0.027 13.8 0.1 0.033 13.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Viral_Hsp90 PF03225.14 CBY40810.1 - 0.049 12.1 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sugar_tr PF00083.24 CBY40810.1 - 0.06 12.2 0.0 0.067 12.0 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Rhomboid PF01694.22 CBY40811.1 - 2.1e-15 57.0 0.4 3.3e-15 56.4 0.4 1.3 1 0 0 1 1 1 1 Rhomboid family EGF_CA PF07645.15 CBY40812.1 - 8.9e-10 38.6 16.4 4.2e-05 23.7 5.8 2.8 3 0 0 3 3 3 2 Calcium-binding EGF domain EGF_3 PF12947.7 CBY40812.1 - 5.1e-05 23.4 6.7 5.1e-05 23.4 6.7 2.9 2 1 0 2 2 2 1 EGF domain EGF PF00008.27 CBY40812.1 - 0.0042 17.4 4.4 0.0042 17.4 4.4 2.8 1 1 0 2 2 2 1 EGF-like domain hEGF PF12661.7 CBY40812.1 - 0.048 14.3 3.3 0.048 14.3 3.3 3.1 4 0 0 4 4 4 0 Human growth factor-like EGF PorB PF11565.8 CBY40812.1 - 0.12 12.8 0.0 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Alpha helical Porin B cEGF PF12662.7 CBY40812.1 - 0.18 11.7 7.4 1.4 9.0 7.4 2.5 1 1 0 1 1 1 0 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY40812.1 - 6.8 7.1 13.7 20 5.6 12.3 2.5 1 1 1 2 2 2 0 Coagulation Factor Xa inhibitory site Pro_isomerase PF00160.21 CBY40814.1 - 7.1e-14 52.4 0.0 7.5e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MOFRL PF05161.13 CBY40815.1 - 3.1e-29 101.4 0.1 4.6e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 MOFRL family DUF4147 PF13660.6 CBY40816.1 - 3.1e-59 200.3 0.0 3.4e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) Lipase_GDSL_2 PF13472.6 CBY40817.1 - 6.7e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FliJ PF02050.16 CBY40817.1 - 0.33 11.2 4.4 0.85 9.9 4.4 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Aa_trans PF01490.18 CBY40818.1 - 1.9e-08 33.4 20.2 1.9e-06 26.8 2.6 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBY40818.1 - 5.8e-05 22.3 4.6 5.8e-05 22.3 4.6 2.7 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Anoctamin PF04547.12 CBY40819.1 - 0.066 12.0 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel TRP PF06011.12 CBY40819.1 - 0.088 11.5 0.1 0.09 11.5 0.1 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SARAF PF06682.12 CBY40819.1 - 0.17 11.5 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DZF PF07528.14 CBY40820.1 - 0.059 13.0 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 DZF domain CUE PF02845.16 CBY40820.1 - 0.18 11.5 0.6 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 CUE domain Gly-rich_Ago1 PF12764.7 CBY40820.1 - 0.39 11.5 7.1 0.28 12.0 5.6 1.5 2 0 0 2 2 2 0 Glycine-rich region of argonaut Tnp_zf-ribbon_2 PF13842.6 CBY40821.1 - 0.021 15.6 0.3 0.045 14.6 0.3 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Frag1 PF10277.9 CBY40822.1 - 3.2e-21 75.9 23.5 3.9e-21 75.6 23.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family UEV PF05743.13 CBY40823.1 - 6.2e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain zf-C3HC4_3 PF13920.6 CBY40823.1 - 1.2e-07 31.5 8.8 2.1e-07 30.7 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY40823.1 - 2.1e-06 27.5 7.8 4e-06 26.6 7.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY40823.1 - 7.2e-06 25.9 11.0 1.2e-05 25.2 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY40823.1 - 5.2e-05 23.5 9.5 9.4e-05 22.7 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain UQ_con PF00179.26 CBY40823.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_UBOX PF13445.6 CBY40823.1 - 0.0016 18.4 3.6 0.012 15.7 3.6 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBY40823.1 - 0.0057 16.5 9.7 0.011 15.6 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY40823.1 - 0.0096 15.8 7.2 0.024 14.5 7.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY40823.1 - 0.088 12.6 8.4 0.22 11.3 8.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 CBY40823.1 - 0.22 10.9 2.2 0.29 10.5 2.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1272 PF06906.11 CBY40823.1 - 0.33 11.1 4.4 0.58 10.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) MMR_HSR1 PF01926.23 CBY40824.1 - 6.9e-14 51.9 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY40824.1 - 8.1e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CBY40824.1 - 3.3e-05 23.3 1.1 5.2e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 CBY40824.1 - 0.00031 20.7 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CBY40824.1 - 0.0011 19.0 6.9 0.0016 18.6 0.2 2.9 2 1 1 3 3 3 1 Dynamin family AAA_15 PF13175.6 CBY40824.1 - 0.0031 17.3 0.2 0.008 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CBY40824.1 - 0.016 15.4 0.1 0.086 13.1 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBY40824.1 - 0.025 14.1 0.1 0.37 10.3 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBY40824.1 - 0.07 13.6 0.0 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Gp_dh_N PF00044.24 CBY40826.1 - 1 9.7 3.8 1 9.7 1.8 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HIP1_clath_bdg PF16515.5 CBY40826.1 - 2.7 8.7 62.7 0.87 10.2 24.3 3.9 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PI3K_P85_iSH2 PF16454.5 CBY40826.1 - 9.4 5.8 64.9 2.5 7.7 13.1 3.3 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain zf-RING_2 PF13639.6 CBY40828.1 - 1.2e-09 38.3 8.4 2.2e-09 37.5 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY40828.1 - 1.1e-07 31.6 6.9 2.3e-07 30.6 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY40828.1 - 3.1e-07 30.3 1.2 6.6e-07 29.3 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBY40828.1 - 4.9e-07 29.5 9.3 1.1e-06 28.4 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY40828.1 - 4.8e-06 26.8 6.8 1.1e-05 25.6 6.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY40828.1 - 5.7e-06 26.2 7.5 1.2e-05 25.1 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBY40828.1 - 1.4e-05 25.0 7.6 4.1e-05 23.5 7.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY40828.1 - 4.5e-05 23.1 7.4 8.8e-05 22.2 7.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBY40828.1 - 6.9e-05 22.9 4.1 6.9e-05 22.9 4.1 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBY40828.1 - 0.00015 21.5 8.2 0.00032 20.5 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY40828.1 - 0.00047 20.0 6.2 0.0011 18.8 6.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBY40828.1 - 0.015 15.1 1.4 0.035 14.0 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 CBY40828.1 - 0.028 14.0 6.9 0.052 13.2 6.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type WD40_alt PF14077.6 CBY40828.1 - 0.056 13.3 0.2 0.056 13.3 0.2 2.9 3 0 0 3 3 2 0 Alternative WD40 repeat motif Leuk-A4-hydro_C PF09127.11 CBY40828.1 - 0.77 9.9 4.6 1.1 9.4 0.2 3.2 4 1 0 4 4 4 0 Leukotriene A4 hydrolase, C-terminal zf-RING_10 PF16685.5 CBY40828.1 - 0.81 9.9 6.1 3.1 8.0 6.1 2.0 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CBY40828.1 - 0.85 9.9 11.7 2.9 8.2 9.1 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 CBY40828.1 - 1.5 8.9 8.1 6.7 6.8 8.2 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1272 PF06906.11 CBY40828.1 - 1.7 8.8 5.3 4.2 7.5 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) GAS PF13851.6 CBY40828.1 - 1.9 7.8 40.3 0.38 10.1 13.3 3.8 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 CBY40828.1 - 5.3 7.2 25.0 3 8.0 1.3 5.6 4 2 1 5 5 5 0 Basic region leucine zipper RabGAP-TBC PF00566.18 CBY40831.1 - 3.2e-42 144.6 0.2 3.2e-42 144.6 0.2 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PID PF00640.23 CBY40831.1 - 0.017 15.2 2.5 5.6 7.0 0.0 3.0 2 1 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) SIN1_PH PF16979.5 CBY40831.1 - 0.06 13.6 0.4 15 5.9 0.1 2.7 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology S-layer PF07752.11 CBY40832.1 - 0.031 13.3 0.1 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 S-layer protein Gln-synt_N PF03951.19 CBY40832.1 - 0.08 12.7 0.0 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain Phospholip_A2_1 PF00068.19 CBY40832.1 - 1.5 9.3 5.1 0.76 10.3 1.2 2.4 2 0 0 2 2 2 0 Phospholipase A2 Flagellin_N PF00669.20 CBY40833.1 - 0.011 15.9 0.6 0.013 15.7 0.6 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF1542 PF07564.11 CBY40833.1 - 0.038 14.1 1.5 0.055 13.6 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Spectrin PF00435.21 CBY40833.1 - 0.05 14.1 0.3 0.065 13.7 0.3 1.1 1 0 0 1 1 1 0 Spectrin repeat HalX PF08663.10 CBY40833.1 - 0.14 12.5 2.7 0.33 11.3 2.4 1.9 1 1 1 2 2 2 0 HalX domain RasGAP PF00616.19 CBY40834.1 - 1.9e-12 47.4 0.1 3e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase 14-3-3 PF00244.20 CBY40835.1 - 2.7e-106 354.0 3.1 3.1e-106 353.9 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein CodY PF06018.14 CBY40835.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Virulence_fact PF13769.6 CBY40835.1 - 1.2 9.4 4.7 0.7 10.2 0.6 2.6 3 0 0 3 3 3 0 Virulence factor Rod-binding PF10135.9 CBY40836.1 - 0.061 13.9 0.8 0.32 11.6 0.0 2.6 3 0 0 3 3 3 0 Rod binding protein FoP_duplication PF13865.6 CBY40837.1 - 2.4e-11 44.0 21.7 7.7e-10 39.2 21.7 2.3 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Peptidase_S30 PF01577.16 CBY40837.1 - 0.09 12.4 16.5 0.11 12.1 16.5 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Ndc1_Nup PF09531.10 CBY40837.1 - 0.68 8.6 16.7 0.84 8.2 16.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 CBY40837.1 - 1.3 8.8 18.2 1.5 8.5 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5427 PF10310.9 CBY40837.1 - 1.3 7.9 17.6 1.5 7.7 17.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 CBY40837.1 - 3 6.8 17.3 3.7 6.5 17.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 CBY40837.1 - 5.2 6.5 13.5 5.9 6.4 13.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4551 PF15087.6 CBY40837.1 - 6.5 5.4 12.0 7.2 5.3 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.16 CBY40837.1 - 9.3 6.2 11.1 11 6.0 11.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YBD PF17725.1 CBY40838.1 - 3.7e-31 108.6 0.4 4.6e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 YAP binding domain TEA PF01285.18 CBY40838.1 - 5.5e-26 90.4 0.0 1.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Mucin PF01456.17 CBY40840.1 - 0.014 15.4 6.1 0.018 15.0 6.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 CBY40840.1 - 4.3 5.4 9.7 5.6 5.0 9.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F5_F8_type_C PF00754.25 CBY40842.1 - 0.003 17.7 0.0 0.0036 17.4 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain A2M PF00207.22 CBY40843.1 - 2.5e-28 97.8 0.1 7.9e-28 96.2 0.1 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family TED_complement PF07678.14 CBY40843.1 - 5.7e-26 91.3 0.0 1.1e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M_BRD PF07703.14 CBY40843.1 - 1.2e-21 77.5 1.1 3.3e-18 66.4 0.1 3.2 2 0 0 2 2 2 2 Alpha-2-macroglobulin bait region domain MG3 PF17791.1 CBY40843.1 - 1.1e-11 44.9 0.4 2e-10 40.8 0.0 3.1 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG2 PF01835.19 CBY40843.1 - 2.6e-11 43.8 0.1 7.7e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 MG2 domain bMG5 PF17972.1 CBY40843.1 - 0.17 12.3 0.0 13 6.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG5 domain FKBP_C PF00254.28 CBY40844.1 - 0.023 15.0 0.1 0.066 13.5 0.0 2.0 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase PDEase_I PF00233.19 CBY40845.1 - 1.4e-53 182.1 1.6 6.2e-44 150.5 0.2 2.2 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Macscav_rec PF03523.13 CBY40845.1 - 0.086 12.7 3.1 0.094 12.6 0.4 2.3 2 0 0 2 2 2 0 Macrophage scavenger receptor LSM PF01423.22 CBY40846.1 - 9e-11 41.3 0.0 1.1e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain Sulfotransfer_1 PF00685.27 CBY40849.1 - 5e-19 68.8 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY40849.1 - 1.6e-07 32.0 0.0 0.32 11.3 0.0 3.3 2 1 1 3 3 3 3 Sulfotransferase family TMPIT PF07851.13 CBY40850.1 - 2.5e-75 253.7 14.3 3e-75 253.5 14.3 1.1 1 0 0 1 1 1 1 TMPIT-like protein Kelch_3 PF13415.6 CBY40851.1 - 2.7e-22 78.5 6.3 6.3e-11 42.3 0.1 5.7 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 CBY40851.1 - 7.3e-19 67.5 5.8 2.2e-05 24.4 0.0 5.1 3 2 1 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY40851.1 - 4.6e-17 61.6 5.1 8.7e-05 22.7 0.2 5.2 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 CBY40851.1 - 7.5e-17 60.9 0.1 9.2e-08 31.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBY40851.1 - 4.2e-15 55.1 8.0 5e-07 29.2 0.1 5.3 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBY40851.1 - 4.7e-10 39.0 2.5 1.6e-05 24.7 0.2 4.2 4 0 0 4 4 4 2 Kelch motif Muskelin_N PF06588.11 CBY40851.1 - 6.4e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus DUF4580 PF15162.6 CBY40851.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) TSP_1 PF00090.19 CBY40853.1 - 3.5e-05 23.9 9.7 0.0001 22.4 9.7 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain zf-C4 PF00105.18 CBY40854.1 - 3.4e-29 101.1 11.5 7.5e-29 100.0 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY40854.1 - 1.3e-13 51.0 9.5 9.1e-13 48.2 9.5 2.3 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor zf-RRPl_C4 PF17026.5 CBY40854.1 - 0.29 11.3 10.5 0.078 13.1 6.8 2.0 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Patched PF02460.18 CBY40855.1 - 7.8e-45 153.3 5.1 1.2e-44 152.7 5.1 1.3 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CBY40855.1 - 5.4e-43 146.5 4.9 1.2e-42 145.4 4.9 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CBY40855.1 - 7.1e-05 21.9 8.4 0.00012 21.1 8.4 1.3 1 0 0 1 1 1 1 MMPL family SPX PF03105.19 CBY40856.1 - 0.16 11.9 7.3 0.17 11.8 7.3 1.0 1 0 0 1 1 1 0 SPX domain GET2 PF08690.10 CBY40856.1 - 0.8 9.3 6.4 0.92 9.1 6.4 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 MSC PF09402.10 CBY40856.1 - 0.84 9.0 6.3 0.91 8.9 6.3 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ribosomal_L6e PF01159.19 CBY40856.1 - 1 9.9 6.5 1.2 9.7 6.2 1.3 1 1 0 1 1 1 0 Ribosomal protein L6e PBP_sp32 PF07222.12 CBY40856.1 - 6.8 6.1 11.0 7.9 5.8 11.0 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.14 CBY40856.1 - 8.3 6.1 12.6 17 5.2 12.6 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Mon2_C PF16206.5 CBY40859.1 - 0.014 13.6 0.1 0.022 12.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal region of Mon2 protein Endonuc_Holl PF10107.9 CBY40860.1 - 0.021 14.7 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF1515 PF07439.11 CBY40861.1 - 0.02 14.9 0.8 0.1 12.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) GldM_N PF12081.8 CBY40861.1 - 0.098 12.7 3.5 0.14 12.2 2.9 1.6 1 1 0 1 1 1 0 GldM N-terminal domain FAM76 PF16046.5 CBY40861.1 - 0.91 8.8 6.4 1.3 8.3 6.4 1.2 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 CBY40861.1 - 2.1 8.8 6.8 4.7 7.6 6.8 1.6 1 1 0 1 1 1 0 Fez1 zf-C2H2 PF00096.26 CBY40862.1 - 1.1e-07 31.9 18.1 0.00043 20.6 6.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY40862.1 - 7.9e-07 29.2 15.8 0.00028 21.2 5.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY40862.1 - 5.4e-06 26.8 16.0 0.0013 19.4 5.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY40862.1 - 0.00012 22.3 8.3 0.084 13.3 1.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY40862.1 - 0.0013 18.7 10.4 0.025 14.6 3.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CBY40862.1 - 0.0055 17.0 6.1 0.015 15.6 1.9 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CBY40862.1 - 0.019 15.1 4.4 0.048 13.8 4.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-DNL PF05180.12 CBY40862.1 - 0.023 14.7 3.3 0.064 13.2 3.3 1.7 1 0 0 1 1 1 0 DNL zinc finger zf-C2H2_jaz PF12171.8 CBY40862.1 - 0.096 13.0 7.3 0.2 12.0 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 CBY40862.1 - 0.097 12.7 2.6 1.3 9.2 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger domain CpXC PF14353.6 CBY40862.1 - 0.22 11.6 2.9 2.3 8.3 0.4 2.5 1 1 1 2 2 2 0 CpXC protein zf-C2H2_3rep PF18868.1 CBY40862.1 - 0.36 11.5 3.9 11 6.7 0.3 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats TFIIS_C PF01096.18 CBY40862.1 - 0.67 9.9 4.5 4.1 7.3 0.3 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2256 PF10013.9 CBY40862.1 - 0.95 9.6 5.3 1.5 9.0 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_4 PF13717.6 CBY40862.1 - 1.2 9.1 4.5 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF629 PF04780.12 CBY40862.1 - 1.3 7.5 7.8 1.7 7.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-AN1 PF01428.16 CBY40862.1 - 1.9 8.7 9.4 8.7 6.6 2.7 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HC_2 PF13913.6 CBY40862.1 - 2.2 8.3 9.6 10 6.2 1.8 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Trypsin PF00089.26 CBY40863.1 - 1.5e-20 74.0 0.2 1.6e-20 73.8 0.2 1.0 1 0 0 1 1 1 1 Trypsin Dynein_C PF18199.1 CBY40864.1 - 9.4e-69 232.0 0.2 1e-68 231.8 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PET PF06297.14 CBY40864.1 - 0.052 13.9 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 PET Domain RIH_assoc PF08454.11 CBY40864.1 - 0.14 12.1 0.0 10 6.0 0.0 2.2 2 0 0 2 2 2 0 RyR and IP3R Homology associated Cnd1 PF12717.7 CBY40866.1 - 1e-12 48.4 5.7 3.3e-07 30.5 0.2 5.1 5 1 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY40866.1 - 2.1e-07 30.6 5.8 0.74 10.2 0.1 6.3 5 0 0 5 5 5 3 HEAT repeat Cnd3 PF12719.7 CBY40866.1 - 1.6e-06 27.5 6.1 9.6e-06 25.0 1.3 3.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 CBY40866.1 - 0.073 13.6 4.4 0.42 11.2 0.1 3.4 3 0 0 3 3 3 0 HEAT-like repeat DUF2674 PF10879.8 CBY40866.1 - 1 8.9 3.6 20 4.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2674) ATP-grasp_2 PF08442.10 CBY40868.1 - 5e-62 209.0 0.3 7e-62 208.6 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBY40868.1 - 5.6e-23 81.4 0.7 5.6e-23 81.4 0.7 1.6 2 0 0 2 2 2 1 CoA-ligase His_Phos_2 PF00328.22 CBY40869.1 - 7.6e-25 88.1 0.0 1.5e-24 87.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VWA_2 PF13519.6 CBY40870.1 - 5.3e-17 62.4 0.4 3.9e-16 59.6 0.1 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 CBY40870.1 - 3.8e-07 30.1 0.3 6.4e-07 29.4 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 CBY40870.1 - 4.9e-07 29.2 16.9 0.00021 21.0 0.9 4.2 4 0 0 4 4 4 3 Ubiquitin interaction motif VWA PF00092.28 CBY40870.1 - 1.8e-06 28.3 0.5 2.9e-06 27.7 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RAP80_UIM PF18282.1 CBY40870.1 - 0.00083 19.1 2.5 0.00083 19.1 2.5 3.3 2 1 0 2 2 2 1 RAP80 N-terminal ubiquitin interaction motif HNOBA PF07701.14 CBY40870.1 - 0.013 15.0 0.1 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 Heme NO binding associated DUF4078 PF13300.6 CBY40871.1 - 2.3e-14 53.5 4.9 2.3e-14 53.5 4.9 3.7 2 2 2 4 4 4 1 Domain of unknown function (DUF4078) MRP-S32 PF10210.9 CBY40872.1 - 7.6e-05 23.2 0.3 0.00017 22.1 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S32 INTS5_N PF14837.6 CBY40873.1 - 2.6e-36 125.2 0.6 2.6e-36 125.2 0.6 2.8 4 0 0 4 4 4 1 Integrator complex subunit 5 N-terminus INTS5_C PF14838.6 CBY40873.1 - 1.4e-27 96.7 5.2 1.4e-27 96.7 5.2 2.3 1 1 1 2 2 2 2 Integrator complex subunit 5 C-terminus N2227 PF07942.12 CBY40873.1 - 0.085 12.0 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 N2227-like protein GGA_N-GAT PF18308.1 CBY40873.1 - 0.2 11.3 5.0 0.13 11.9 0.3 3.0 3 0 0 3 3 3 0 GGA N-GAT domain B9-C2 PF07162.11 CBY40875.1 - 6.5e-27 94.8 0.0 1e-26 94.2 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4106 PF13388.6 CBY40876.1 - 0.36 10.0 10.0 0.56 9.4 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TFIIA PF03153.13 CBY40876.1 - 0.96 9.4 10.2 1.3 8.9 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lectin_C PF00059.21 CBY40877.1 - 1.2e-48 164.3 20.5 1.9e-18 67.1 1.9 4.5 4 0 0 4 4 4 4 Lectin C-type domain UL45 PF05473.12 CBY40877.1 - 2.3e-06 27.4 5.1 0.074 12.7 0.0 3.9 3 1 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Chordopox_A33R PF05966.12 CBY40877.1 - 0.017 14.4 2.5 4.3 6.6 0.6 2.7 2 1 1 3 3 3 0 Chordopoxvirus A33R protein Phospholip_A2_1 PF00068.19 CBY40879.1 - 2.8e-09 37.4 11.1 2.8e-09 37.4 11.1 2.0 2 0 0 2 2 2 1 Phospholipase A2 DUF1547 PF07577.11 CBY40879.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) Ig_3 PF13927.6 CBY40880.1 - 0.0025 18.4 3.1 0.11 13.1 0.2 3.6 4 1 0 4 4 4 1 Immunoglobulin domain DUF2500 PF10694.9 CBY40880.1 - 0.059 13.9 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF4330 PF14221.6 CBY40880.1 - 0.092 13.0 0.2 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) Stevor PF17410.2 CBY40880.1 - 0.12 11.9 0.2 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 CBY40880.1 - 0.12 13.2 0.0 0.28 12.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Galactosyl_T PF01762.21 CBY40881.1 - 1e-20 74.4 0.0 2.4e-20 73.2 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase DUF3417 PF11897.8 CBY40881.1 - 0.37 11.2 2.4 38 4.8 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) CASP_C PF08172.12 CBY40882.1 - 0.0011 18.4 8.4 0.0012 18.2 8.4 1.0 1 0 0 1 1 1 1 CASP C terminal ALAD PF00490.21 CBY40883.1 - 1.7e-111 372.5 0.0 2.1e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF_TS PF00889.19 CBY40884.1 - 8.4e-09 35.3 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor TS TAP_C PF03943.13 CBY40884.1 - 8e-05 22.2 0.4 0.00025 20.6 0.1 2.0 2 0 0 2 2 2 1 TAP C-terminal domain UBA PF00627.31 CBY40884.1 - 0.022 14.6 0.1 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 UBA/TS-N domain UBA_4 PF14555.6 CBY40884.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF4295 PF14128.6 CBY40885.1 - 0.15 11.9 0.0 2.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Acyl_transf_3 PF01757.22 CBY40886.1 - 0.023 13.7 0.3 0.027 13.6 0.3 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF3938 PF13074.6 CBY40886.1 - 0.026 14.8 0.4 0.062 13.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) SLATT_5 PF18160.1 CBY40886.1 - 0.028 13.8 2.4 0.55 9.5 0.0 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Bax1-I PF01027.20 CBY40886.1 - 0.032 14.0 2.7 0.065 13.1 2.7 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 HlyIII PF03006.20 CBY40886.1 - 0.059 13.1 2.4 0.093 12.4 2.4 1.3 1 1 0 1 1 1 0 Haemolysin-III related DUF2985 PF11204.8 CBY40886.1 - 0.1 12.8 0.5 0.34 11.1 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) EGF_CA PF07645.15 CBY40887.1 - 1.3e-05 25.3 5.6 1.3e-05 25.3 5.6 3.3 3 1 0 3 3 3 1 Calcium-binding EGF domain Phospholip_A2_1 PF00068.19 CBY40888.1 - 2.5e-07 31.2 1.2 2.6e-07 31.1 0.1 1.5 2 0 0 2 2 2 1 Phospholipase A2 DUF547 PF04784.14 CBY40889.1 - 1.1e-33 115.8 0.0 2.1e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 CBY40889.1 - 0.0042 17.1 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4520 PF15016.6 CBY40889.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF5032 PF16435.5 CBY40889.1 - 0.057 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5032) Glutaredoxin PF00462.24 CBY40889.1 - 0.12 12.6 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin Trypsin PF00089.26 CBY40891.1 - 2e-24 86.6 0.1 2.4e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin PF00089.26 CBY40892.1 - 1.8e-11 44.3 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin Glyco_hydro_35 PF01301.19 CBY40893.1 - 1.6e-85 287.6 1.0 1.9e-85 287.3 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CBY40893.1 - 3.5e-14 53.0 0.3 1.8e-13 50.6 0.0 2.1 2 1 0 2 2 2 1 Beta-galactosidase Amidohydro_2 PF04909.14 CBY40893.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Ammonium_transp PF00909.21 CBY40898.1 - 3.3e-75 253.3 19.1 5.7e-74 249.2 19.1 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family PrsW-protease PF13367.6 CBY40898.1 - 0.0053 16.2 0.2 0.0053 16.2 0.2 2.5 4 0 0 4 4 4 1 PrsW family intramembrane metalloprotease ThrE PF06738.12 CBY40898.1 - 0.1 12.0 0.0 0.1 12.0 0.0 2.9 3 1 0 3 3 3 0 Putative threonine/serine exporter DUF2583 PF10762.9 CBY40898.1 - 0.44 11.0 4.6 2.4 8.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Neurensin PF14927.6 CBY40898.1 - 1.6 8.5 5.4 3 7.5 0.2 2.8 1 1 1 2 2 2 0 Neurensin DUF1129 PF06570.11 CBY40898.1 - 1.9 7.9 11.8 0.073 12.5 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) EGF PF00008.27 CBY40899.1 - 0.82 10.0 19.0 1.3 9.4 7.3 2.5 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 CBY40899.1 - 8.1 6.9 18.7 6.3 7.3 9.3 2.4 2 0 0 2 2 2 0 EGF-like domain Trypsin PF00089.26 CBY40900.1 - 1.5e-07 31.4 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin Sina PF03145.16 CBY40900.1 - 0.14 12.1 8.1 1.9 8.4 0.7 2.2 2 0 0 2 2 2 0 Seven in absentia protein family Abhydrolase_2 PF02230.16 CBY40901.1 - 9.8e-62 208.6 0.0 1.2e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY40901.1 - 1.8e-12 47.0 0.0 4.6e-05 22.8 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 CBY40901.1 - 1.7e-09 37.6 0.0 1.7e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 CBY40901.1 - 2.1e-09 37.4 0.0 1.1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CBY40901.1 - 5.4e-08 32.6 0.1 0.019 14.5 0.0 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family Esterase PF00756.20 CBY40901.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CBY40901.1 - 7.7e-06 25.7 0.6 0.0088 15.7 0.3 3.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CBY40901.1 - 0.00011 20.9 0.0 0.00018 20.2 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 CBY40901.1 - 0.00027 20.9 0.0 0.074 12.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 CBY40901.1 - 0.00054 19.8 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBY40901.1 - 0.0016 19.1 0.0 0.0026 18.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CBY40901.1 - 0.0029 16.3 0.0 0.0043 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 CBY40901.1 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Palm_thioest PF02089.15 CBY40901.1 - 0.006 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase BAAT_C PF08840.11 CBY40901.1 - 0.0063 16.5 0.0 4.1 7.3 0.1 3.0 2 1 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase_phd PF10503.9 CBY40901.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Cutinase PF01083.22 CBY40901.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 CBY40901.1 - 0.09 12.3 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_4 PF08386.10 CBY40901.1 - 0.1 12.7 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein PGAP1 PF07819.13 CBY40901.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Cornichon PF03311.14 CBY40902.1 - 8.7e-38 129.4 4.4 1e-37 129.2 4.4 1.0 1 0 0 1 1 1 1 Cornichon protein Diphthamide_syn PF01866.17 CBY40903.1 - 1.8e-54 185.2 0.0 1.2e-53 182.5 0.0 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein TPT PF03151.16 CBY40904.1 - 2e-20 73.3 16.5 2.4e-20 73.1 16.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY40904.1 - 1.3e-06 28.6 21.8 3.9e-05 23.8 6.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family ADP_PFK_GK PF04587.15 CBY40906.1 - 7.7e-09 34.6 0.0 8.2e-09 34.5 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region ADP_PFK_GK PF04587.15 CBY40907.1 - 2.2e-107 359.3 0.0 2.8e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Helicase_C PF00271.31 CBY40908.1 - 3.7e-28 98.1 0.0 6.6e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNApol_Exo PF18136.1 CBY40909.1 - 2.5e-65 220.4 0.0 5e-65 219.4 0.0 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CBY40909.1 - 7.1e-26 91.1 0.0 1.2e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A PP1_bind PF15276.6 CBY40909.1 - 0.075 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 binding DUF3945 PF13101.6 CBY40910.1 - 0.1 12.4 1.4 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) GTP_EFTU_D3 PF03143.17 CBY40911.1 - 1.6e-11 44.5 0.1 2.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBY40911.1 - 6.1e-06 26.5 0.4 3.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Zona_pellucida PF00100.23 CBY40912.1 - 1.4e-26 93.9 6.4 2e-26 93.3 6.4 1.2 1 0 0 1 1 1 1 Zona pellucida-like domain Thioredoxin PF00085.20 CBY40912.1 - 1.4e-25 89.3 0.0 1.2e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CBY40912.1 - 0.00038 20.9 0.4 1.8 9.0 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBY40912.1 - 0.057 13.6 0.6 4.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY40912.1 - 0.064 13.6 0.1 0.87 10.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Cut8 PF08559.10 CBY40912.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Carb_anhydrase PF00194.21 CBY40913.1 - 1.3e-59 201.8 0.0 1.6e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VioE PF18234.1 CBY40914.1 - 0.15 12.2 0.3 0.19 11.9 0.3 1.1 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE Sacchrp_dh_C PF16653.5 CBY40916.1 - 8.9e-74 248.9 0.0 1.5e-73 248.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CBY40916.1 - 2.8e-19 69.6 0.1 4.4e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBY40916.1 - 0.00041 20.4 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CBY40916.1 - 0.0036 17.7 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 CBY40916.1 - 0.011 16.3 1.7 0.19 12.3 0.1 3.2 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase IF2_N PF04760.15 CBY40916.1 - 0.016 15.0 0.1 0.085 12.7 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NmrA PF05368.13 CBY40916.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pyr_redox_2 PF07992.14 CBY40916.1 - 0.045 13.0 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 CBY40916.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CBY40916.1 - 0.071 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Annexin PF00191.20 CBY40917.1 - 2e-11 43.8 0.3 2.6e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 Annexin Imm64 PF15600.6 CBY40917.1 - 0.012 15.4 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 64 Mt_ATP-synt_D PF05873.12 CBY40918.1 - 0.003 17.4 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PHM7_cyt PF14703.6 CBY40918.1 - 0.012 15.9 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CHD5 PF04420.14 CBY40918.1 - 0.072 12.9 0.8 0.72 9.7 0.3 2.1 2 0 0 2 2 2 0 CHD5-like protein Pkinase PF00069.25 CBY40919.1 - 3.5e-09 36.4 0.1 3.5e-09 36.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40919.1 - 0.0001 21.7 0.0 0.00011 21.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_18 PF18014.1 CBY40921.1 - 3.4e-14 52.8 0.0 8.4e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY40921.1 - 3e-13 50.0 0.2 1.3e-10 41.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY40921.1 - 4.8e-09 36.2 0.0 6.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY40921.1 - 2e-06 28.2 0.0 7.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CBY40921.1 - 0.00055 20.6 0.0 0.0014 19.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2706 PF10913.8 CBY40921.1 - 0.01 15.7 0.4 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) FR47 PF08445.10 CBY40921.1 - 0.016 15.2 0.1 0.041 13.8 0.1 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CBY40921.1 - 0.023 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase VEG PF06257.11 CBY40921.1 - 0.063 13.3 0.4 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 Biofilm formation stimulator VEG DUF4760 PF15956.5 CBY40921.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) Acetyltransf_9 PF13527.7 CBY40921.1 - 0.11 12.6 0.1 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Kelch_6 PF13964.6 CBY40922.1 - 1.6e-06 28.2 4.8 2.4 8.6 0.1 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 CBY40922.1 - 0.019 14.5 2.6 18 5.0 0.0 4.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 CBY40922.1 - 0.89 9.9 7.4 19 5.7 0.1 4.7 5 1 0 5 5 5 0 Galactose oxidase, central domain Pkinase PF00069.25 CBY40923.1 - 2.7e-22 79.4 0.0 5.9e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40923.1 - 1.1e-06 28.2 0.0 6.1e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase PKcGMP_CC PF16808.5 CBY40923.1 - 1.2 9.1 6.2 3.2 7.7 6.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CAF1A PF12253.8 CBY40924.1 - 0.12 12.6 1.0 0.16 12.1 1.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Band_3_cyto PF07565.13 CBY40927.1 - 2.5e-12 47.2 1.1 4.4e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 Band 3 cytoplasmic domain UQ_con PF00179.26 CBY40928.1 - 2e-43 147.4 0.0 3.1e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY40928.1 - 0.0034 17.1 0.0 0.015 15.0 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CBY40928.1 - 0.038 14.3 0.9 0.089 13.1 0.1 2.0 1 1 1 2 2 2 0 RWD domain PHTB1_N PF14727.6 CBY40929.1 - 1.9e-25 90.1 0.7 2.5e-25 89.7 0.7 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus CLTH PF10607.9 CBY40929.1 - 0.12 12.3 2.4 0.26 11.1 2.4 1.6 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain zf-C3HC4_2 PF13923.6 CBY40930.1 - 1.6e-10 40.6 25.5 8.4e-08 31.9 8.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY40930.1 - 1.1e-09 38.4 27.4 1.3e-08 35.0 8.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CBY40930.1 - 1.2e-09 37.8 27.5 8.6e-08 31.9 9.7 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY40930.1 - 1.4e-09 37.7 24.4 7.8e-06 25.7 8.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY40930.1 - 8.3e-09 35.3 22.1 1.5e-05 24.9 6.4 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 CBY40930.1 - 2.8e-08 33.6 26.9 0.00016 21.6 9.2 2.4 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY40930.1 - 0.00041 20.1 26.2 0.092 12.6 4.1 3.5 2 1 1 3 3 3 3 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY40930.1 - 0.00046 20.3 11.7 0.00046 20.3 11.7 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY40930.1 - 0.0012 19.1 5.8 0.0012 19.1 5.8 2.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY40930.1 - 0.0027 17.7 2.0 0.0027 17.7 2.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY40930.1 - 0.0099 15.6 9.2 0.0099 15.6 9.2 3.4 2 2 2 4 4 4 1 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 CBY40930.1 - 0.036 14.3 4.3 0.5 10.7 0.1 3.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 CBY40930.1 - 0.15 11.9 7.8 0.34 10.8 7.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit GAGA PF09237.11 CBY40930.1 - 9.3 6.2 8.1 9 6.2 0.2 3.0 2 1 1 3 3 3 0 GAGA factor Connexin PF00029.19 CBY40931.1 - 0.75 9.5 11.0 0.031 14.0 4.1 2.0 2 0 0 2 2 2 0 Connexin ORC_WH_C PF18137.1 CBY40931.1 - 3.6 7.7 13.3 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RNA_pol_Rpc4 PF05132.14 CBY40931.1 - 4 7.9 9.6 1.4 9.3 4.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 ETRAMP PF09716.10 CBY40931.1 - 6.3 6.9 6.3 1.1e+02 2.9 0.0 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3916 PF13079.6 CBY40933.1 - 0.046 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Pkinase PF00069.25 CBY40934.1 - 1e-09 38.2 0.0 3.2e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40934.1 - 0.00047 19.5 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_tail_1 PF01576.19 CBY40935.1 - 8.4e-70 235.8 132.1 9.6e-70 235.6 132.1 1.0 1 0 0 1 1 1 1 Myosin tail Tropomyosin PF00261.20 CBY40935.1 - 3.9 6.8 136.9 0.043 13.2 19.5 5.4 1 1 4 5 5 5 0 Tropomyosin GDI PF00996.18 CBY40936.1 - 7.9e-183 607.9 0.0 9.1e-183 607.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.22 CBY40937.1 - 1.4e-16 60.1 0.0 2.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 CBY40937.1 - 0.054 12.4 0.9 0.065 12.1 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Glyco_hydro_38N PF01074.22 CBY40937.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Homeodomain PF00046.29 CBY40939.1 - 1.6e-21 75.9 3.3 3.2e-21 74.9 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY40939.1 - 0.0088 15.9 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF4542 PF15075.6 CBY40939.1 - 0.083 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) OTOS PF15182.6 CBY40939.1 - 0.13 12.1 0.4 0.37 10.7 0.2 1.8 2 0 0 2 2 2 0 Otospiralin Auxin_canalis PF05703.11 CBY40939.1 - 0.21 11.5 2.4 0.24 11.3 1.1 1.6 1 1 1 2 2 2 0 Auxin canalisation Galactosyl_T PF01762.21 CBY40941.1 - 2.7e-14 53.4 0.0 6.3e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Galactosyltransferase BAR PF03114.18 CBY40941.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 BAR domain HTH_32 PF13565.6 CBY40942.1 - 0.025 15.2 0.3 0.034 14.8 0.3 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Cnn_1N PF07989.11 CBY40943.1 - 0.0012 19.0 6.9 0.0012 19.0 6.9 7.8 4 1 2 6 6 6 3 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 CBY40943.1 - 0.1 12.7 77.7 0.07 13.2 8.4 6.6 3 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein DUF2617 PF10936.8 CBY40943.1 - 0.61 10.2 5.0 0.88 9.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF2617 Csm1_N PF18504.1 CBY40943.1 - 2.3 8.6 0.0 2.3 8.6 0.0 8.6 4 1 3 9 9 9 0 Csm1 N-terminal domain Guanylate_cyc PF00211.20 CBY40944.1 - 1.9e-31 109.1 0.0 4.4e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 CBY40944.1 - 8.4e-16 58.0 0.1 8.2e-14 51.5 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY40944.1 - 2e-08 33.9 0.3 0.078 12.3 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain HNOBA PF07701.14 CBY40944.1 - 0.00025 20.5 0.7 0.00025 20.5 0.7 1.6 2 0 0 2 2 2 1 Heme NO binding associated Phospholip_A2_1 PF00068.19 CBY40945.1 - 1.2e-13 51.6 6.7 1.2e-13 51.6 6.7 2.1 2 0 0 2 2 2 1 Phospholipase A2 zf-C2H2_4 PF13894.6 CBY40948.1 - 2.1e-05 25.0 10.8 0.025 15.4 2.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY40948.1 - 9.6e-05 22.6 11.1 0.053 14.0 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CBY40948.1 - 0.021 15.5 6.8 0.21 12.3 3.7 2.3 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CBY40948.1 - 0.032 14.5 10.1 0.17 12.2 2.9 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY40948.1 - 0.1 13.0 6.3 0.7 10.4 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF836 PF05768.14 CBY40948.1 - 1.3 9.5 3.9 3.4 8.2 0.3 2.4 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) zf-H2C2_2 PF13465.6 CBY40948.1 - 5.5 7.6 11.1 1.3 9.6 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain PG_binding_2 PF08823.11 CBY40949.1 - 0.0013 19.0 0.0 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative peptidoglycan binding domain PG_binding_1 PF01471.18 CBY40949.1 - 0.013 15.7 0.2 0.82 9.9 0.2 3.2 3 2 1 4 4 4 0 Putative peptidoglycan binding domain FMO-like PF00743.19 CBY40950.1 - 2.4e-20 72.5 1.3 2.8e-19 69.0 1.3 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CBY40950.1 - 9e-12 44.9 0.0 6.9e-11 41.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBY40950.1 - 4.6e-11 42.5 0.0 4.9e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBY40950.1 - 3e-08 33.8 0.0 8.2e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBY40950.1 - 2e-07 30.6 0.0 0.00029 20.2 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CBY40950.1 - 9.3e-05 22.5 0.0 0.32 11.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 CBY40950.1 - 0.00024 20.8 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CBY40950.1 - 0.0016 18.4 0.0 2.1 8.3 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 CBY40950.1 - 0.0032 16.8 0.0 0.0067 15.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CBY40950.1 - 0.0064 17.0 0.1 0.061 13.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CBY40950.1 - 0.018 15.5 0.0 0.62 10.5 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 CBY40950.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CBY40950.1 - 0.048 13.0 0.1 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY40950.1 - 0.11 12.0 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_S9 PF00380.19 CBY40952.1 - 3.1e-32 111.6 0.6 3.5e-32 111.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.19 CBY40953.1 - 1.1e-36 125.8 2.4 1.2e-36 125.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CBY40953.1 - 2.2e-06 27.8 6.3 2.2e-06 27.8 6.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L6, N-terminal domain P30 PF07390.11 CBY40953.1 - 0.038 14.1 0.1 0.038 14.1 0.1 1.6 2 0 0 2 2 2 0 Mycoplasma P30 protein Nuc_sug_transp PF04142.15 CBY40954.1 - 8.9e-126 419.3 22.2 1.1e-125 419.0 22.2 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY40954.1 - 6.6e-07 29.6 33.0 0.00035 20.8 15.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family Alk_phosphatase PF00245.20 CBY40956.1 - 3.7e-22 78.9 0.0 4.9e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Steroid_dh PF02544.16 CBY40958.1 - 1.9e-18 66.9 8.3 3.8e-18 65.9 8.3 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase S_100 PF01023.19 CBY40958.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Ndc1_Nup PF09531.10 CBY40961.1 - 2.2e-29 102.6 26.9 1.7e-28 99.7 26.9 1.9 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup 5_nucleotid PF05761.14 CBY40962.1 - 1.4e-22 80.3 2.7 1.7e-22 80.0 2.7 1.1 1 0 0 1 1 1 1 5' nucleotidase family DUF4200 PF13863.6 CBY40963.1 - 3e-16 59.9 4.6 3e-16 59.9 4.6 4.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4200) TBCA PF02970.16 CBY40963.1 - 0.003 17.8 1.6 0.003 17.8 1.6 3.9 3 2 0 3 3 3 1 Tubulin binding cofactor A Syntaxin-6_N PF09177.11 CBY40963.1 - 0.017 15.6 0.4 0.017 15.6 0.4 3.9 3 1 0 4 4 4 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 CBY40963.1 - 0.028 14.6 3.4 0.028 14.6 3.4 3.5 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CBY40963.1 - 0.13 12.3 5.9 4 7.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 CBY40963.1 - 5.3 7.1 9.4 0.64 10.0 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) YvrJ PF12841.7 CBY40963.1 - 7.6 6.2 6.1 30 4.3 0.2 3.3 3 1 0 3 3 3 0 YvrJ protein family zf-MYND PF01753.18 CBY40964.1 - 0.0014 18.7 16.3 0.0034 17.4 16.3 1.7 1 0 0 1 1 1 1 MYND finger Alpha_adaptin_C PF02296.16 CBY40965.1 - 1.7e-27 95.8 0.0 3.5e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CBY40965.1 - 4.8e-12 46.2 0.5 2.6e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Coatomer_g_Cpla PF16381.5 CBY40965.1 - 0.014 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform B2-adapt-app_C PF09066.10 CBY40965.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain ABC_transp_aux PF09822.9 CBY40966.1 - 1.9e-08 34.1 0.0 1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 CBY40966.1 - 2.5e-05 23.3 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 CBY40966.1 - 0.003 18.0 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) DUF2194 PF09960.9 CBY40966.1 - 0.031 12.6 0.1 0.043 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Pkinase PF00069.25 CBY40967.1 - 2.3e-56 191.1 0.0 2.9e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40967.1 - 8.9e-25 87.4 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_N PF08240.12 CBY40968.1 - 2.2e-09 37.1 0.0 1.7e-08 34.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SecY PF00344.20 CBY40969.1 - 3.2e-34 118.6 8.2 5.1e-34 117.9 8.2 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBY40969.1 - 8.1e-18 64.0 0.2 2e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p Abhydrolase_9_N PF15420.6 CBY40969.1 - 0.69 9.9 3.7 0.97 9.4 0.1 2.5 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus RRM_1 PF00076.22 CBY40970.1 - 1.6e-26 91.9 0.1 1.8e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY40970.1 - 5.5e-10 39.2 0.1 0.00065 19.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 CBY40970.1 - 0.073 13.1 2.0 0.41 10.7 0.1 2.5 3 0 0 3 3 3 0 RNA binding motif 7tm_6 PF02949.20 CBY40971.1 - 0.32 10.0 11.2 0.24 10.4 4.4 2.1 1 1 1 2 2 2 0 7tm Odorant receptor DUF3270 PF11674.8 CBY40971.1 - 2.2 8.5 4.7 0.85 9.8 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Phospholip_A2_1 PF00068.19 CBY40973.1 - 6.4e-15 55.6 5.4 6.4e-15 55.6 5.4 2.1 3 0 0 3 3 3 1 Phospholipase A2 RVT_1 PF00078.27 CBY40974.1 - 8.9e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY40974.1 - 2.5e-10 40.6 0.0 4.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain GBR2_CC PF18455.1 CBY40974.1 - 0.019 15.1 1.9 0.066 13.3 1.9 1.9 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain zf-CCHC PF00098.23 CBY40974.1 - 0.023 14.8 7.4 0.046 13.8 7.4 1.5 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.6 CBY40974.1 - 0.22 11.3 4.0 0.34 10.7 0.0 3.2 3 0 0 3 3 3 0 Integrase core domain zf-CCHC_5 PF14787.6 CBY40974.1 - 7.5 6.4 9.5 0.56 10.0 4.2 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Phospholip_A2_1 PF00068.19 CBY40976.1 - 4e-10 40.2 7.5 4e-10 40.2 7.5 1.7 2 0 0 2 2 2 1 Phospholipase A2 NCD1 PF04904.13 CBY40977.1 - 6.2e-34 115.8 0.3 1.1e-33 115.0 0.3 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) CbbQ_C PF08406.10 CBY40977.1 - 0.0044 17.2 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Pil1 PF13805.6 CBY40977.1 - 0.082 12.4 0.7 0.3 10.5 0.6 1.8 1 1 1 2 2 2 0 Eisosome component PIL1 SseC PF04888.12 CBY40977.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CNOT1_TTP_bind PF16417.5 CBY40978.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain MotY_N PF18393.1 CBY40978.1 - 0.16 12.1 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 MotY N-terminal domain Trypsin PF00089.26 CBY40979.1 - 5.8e-107 356.5 17.0 5.2e-49 167.0 1.8 3.2 3 0 0 3 3 3 3 Trypsin Trypsin_2 PF13365.6 CBY40979.1 - 6.6e-15 56.3 6.7 1.5e-05 26.0 0.0 4.3 3 1 1 4 4 4 2 Trypsin-like peptidase domain Peptidase_C4 PF00863.19 CBY40979.1 - 0.3 10.4 1.1 0.56 9.5 0.1 2.0 2 0 0 2 2 2 0 Peptidase family C4 Pkinase PF00069.25 CBY40980.1 - 2.7e-11 43.3 1.3 3.3e-11 43.0 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY40980.1 - 1.5e-09 37.5 0.1 2.7e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PTR2 PF00854.21 CBY40981.1 - 3.6e-75 253.3 13.5 5.8e-46 157.1 4.3 2.1 1 1 1 2 2 2 2 POT family Y_phosphatase PF00102.27 CBY40982.1 - 1.5e-62 211.2 0.0 1.9e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBY40982.1 - 0.0003 20.6 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBY40982.1 - 0.022 14.7 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBY40982.1 - 0.032 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 CBY40983.1 - 3e-22 78.5 3.7 0.0012 19.6 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY40983.1 - 7.6e-10 39.0 0.0 0.0049 17.1 0.0 5.8 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBY40983.1 - 0.00016 21.6 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 CBY40983.1 - 0.00074 19.9 3.0 6.7 7.3 0.0 5.3 6 0 0 6 6 6 1 PQQ-like domain PQQ_2 PF13360.6 CBY40983.1 - 0.0078 15.8 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Helicase_C PF00271.31 CBY40985.1 - 1e-19 70.9 0.6 1.3e-18 67.3 0.0 3.0 3 1 1 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY40985.1 - 5.6e-15 55.5 0.0 7.9e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CBY40985.1 - 5e-09 36.7 1.5 1.5e-08 35.2 1.5 1.8 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 CBY40985.1 - 4.3e-06 26.5 0.1 1.4e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 CBY40985.1 - 0.00051 20.1 0.8 0.0094 16.0 0.0 3.0 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit Collagen PF01391.18 CBY40987.1 - 4e-07 29.7 14.0 7.9e-07 28.8 14.0 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DASH_Dad4 PF08650.10 CBY40987.1 - 0.88 9.6 4.8 10 6.2 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad4 Na_H_Exchanger PF00999.21 CBY40988.1 - 5.5e-71 239.4 34.6 7.2e-71 239.0 34.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Collagen PF01391.18 CBY40989.1 - 1.5e-19 69.5 61.1 5 7.0 61.1 3.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M18 PF02127.15 CBY40990.1 - 7.6e-104 347.9 0.0 8.5e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) BRCT PF00533.26 CBY40991.1 - 3.9e-20 72.0 0.1 1.2e-06 28.8 0.0 4.0 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY40991.1 - 5.5e-16 58.7 0.3 1.6e-05 25.2 0.3 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CBY40991.1 - 2.2e-13 49.9 0.0 2.1e-10 40.4 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain BRCT_3 PF18428.1 CBY40991.1 - 7.5e-07 29.2 0.4 0.0094 16.0 0.1 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBY40991.1 - 5.1e-05 23.5 1.9 0.018 15.3 0.0 4.0 4 1 0 4 4 4 1 DNA ligase 3 BRCT domain Homeodomain PF00046.29 CBY40993.1 - 7.4e-21 73.8 2.5 1.3e-20 73.0 2.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY40993.1 - 0.0039 17.1 0.1 0.012 15.5 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Polyketide_cyc PF03364.20 CBY40993.1 - 0.038 14.2 2.0 0.056 13.6 2.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport MutS_IV PF05190.18 CBY40993.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV Exo84_C PF16528.5 CBY40994.1 - 1.6e-24 86.9 4.6 4.4e-23 82.2 4.6 2.0 1 1 0 1 1 1 1 Exocyst component 84 C-terminal EGF PF00008.27 CBY40995.1 - 2.2e-11 43.8 110.5 0.0003 21.0 8.0 9.0 8 0 0 8 8 8 6 EGF-like domain EGF_2 PF07974.13 CBY40995.1 - 1.1e-07 32.1 137.0 0.0033 17.8 12.9 9.3 8 1 0 8 8 8 6 EGF-like domain hEGF PF12661.7 CBY40995.1 - 0.0019 18.8 97.6 0.025 15.2 5.9 9.6 8 0 0 8 8 8 5 Human growth factor-like EGF EGF_Tenascin PF18720.1 CBY40995.1 - 0.48 10.5 44.0 0.47 10.5 4.5 6.6 5 0 0 5 5 5 0 Tenascin EGF domain Prominin PF05478.11 CBY40997.1 - 1 7.2 2.4 1.7 6.5 2.4 1.3 1 0 0 1 1 1 0 Prominin MtN3_slv PF03083.16 CBY41000.1 - 4.8e-38 129.1 14.4 2.3e-21 75.6 0.8 2.3 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange UPF0139 PF03669.13 CBY41000.1 - 0.11 12.4 0.2 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) SR-25 PF10500.9 CBY41001.1 - 0.0025 17.5 23.3 0.0025 17.5 23.3 3.2 1 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein AT_hook PF02178.19 CBY41001.1 - 0.074 13.0 4.9 0.31 11.1 4.9 2.2 1 0 0 1 1 1 0 AT hook motif Herpes_pp85 PF04637.12 CBY41001.1 - 3.6 5.9 9.0 5.9 5.2 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FAM24 PF15193.6 CBY41002.1 - 2.7 8.8 8.7 0.21 12.4 1.3 3.0 3 0 0 3 3 3 0 FAM24 family Phospholip_A2_1 PF00068.19 CBY41003.1 - 1.5e-13 51.2 3.8 1.5e-13 51.2 3.8 2.3 2 0 0 2 2 2 1 Phospholipase A2 Shisa PF13908.6 CBY41004.1 - 0.0034 17.7 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 CBY41004.1 - 0.0096 15.7 1.7 0.014 15.2 1.7 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Cadherin_C_2 PF16492.5 CBY41004.1 - 0.012 16.3 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Tweety PF04906.13 CBY41004.1 - 0.026 13.2 0.1 0.033 12.8 0.1 1.1 1 0 0 1 1 1 0 Tweety TMEM132D_C PF15706.5 CBY41004.1 - 0.045 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SID-1_RNA_chan PF13965.6 CBY41004.1 - 0.06 11.8 0.0 0.062 11.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ETRAMP PF09716.10 CBY41004.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMEM52 PF14979.6 CBY41004.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane 52 LZ3wCH PF18517.1 CBY41007.1 - 3.8 7.7 7.1 23 5.2 0.2 4.1 2 1 1 3 3 3 0 Leucine zipper with capping helix domain DUF87 PF01935.17 CBY41008.1 - 3.2 7.8 9.1 0.28 11.2 2.9 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain RabGAP-TBC PF00566.18 CBY41011.1 - 8.4e-39 133.4 3.9 1.3e-38 132.8 3.9 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Usg PF06233.12 CBY41011.1 - 0.0068 16.5 0.2 0.02 15.1 0.0 1.8 2 0 0 2 2 2 1 Usg-like family PRP38 PF03371.15 CBY41012.1 - 9.2e-59 198.2 0.7 1.1e-58 198.0 0.7 1.1 1 0 0 1 1 1 1 PRP38 family Fur_reg_FbpA PF13076.6 CBY41012.1 - 0.045 13.4 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein A bZIP_2 PF07716.15 CBY41013.1 - 0.01 15.9 0.4 0.01 15.9 0.4 3.0 3 1 0 3 3 3 0 Basic region leucine zipper DUF3544 PF12064.8 CBY41013.1 - 0.072 13.4 0.7 0.083 13.2 0.7 1.1 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 Nup54 PF13874.6 CBY41013.1 - 0.34 11.0 5.4 0.27 11.3 4.4 1.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 PID PF00640.23 CBY41015.1 - 8.4e-32 110.1 0.3 1.5e-31 109.3 0.3 1.5 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) PDZ PF00595.24 CBY41015.1 - 1.7e-26 92.4 3.0 5.7e-12 45.8 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY41015.1 - 6.1e-15 54.8 0.3 2e-06 27.6 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 CBY41015.1 - 4.6e-06 26.9 0.1 0.0019 18.5 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Sushi PF00084.20 CBY41016.1 - 0.72 10.5 9.7 0.1 13.2 2.2 2.6 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) CD99L2 PF12301.8 CBY41016.1 - 1.9 8.8 4.6 4.1 7.7 0.6 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 Phage_integrase PF00589.22 CBY41017.1 - 3.6e-09 36.6 0.0 8.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Glyco_transf_8 PF01501.20 CBY41019.1 - 0.015 14.9 0.6 2.2 7.8 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase family 8 IBR PF01485.21 CBY41020.1 - 4.3e-10 39.7 27.3 1.8e-07 31.2 4.0 5.1 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 CBY41020.1 - 2.6e-06 27.8 1.9 2.6e-06 27.8 1.9 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF3330 PF11809.8 CBY41020.1 - 0.0047 17.0 1.5 0.0047 17.0 1.5 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3330) Pro_isomerase PF00160.21 CBY41021.1 - 1.3e-41 142.6 0.5 1.6e-41 142.2 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF739 PF05339.11 CBY41021.1 - 0.032 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF739) Pro_isomerase PF00160.21 CBY41022.1 - 7.1e-47 159.6 0.3 8.5e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gal_Lectin PF02140.18 CBY41023.1 - 1.1e-16 61.0 0.3 1.7e-16 60.4 0.3 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain VWA PF00092.28 CBY41024.1 - 0.087 13.1 0.1 0.32 11.2 0.0 1.9 2 1 0 2 2 2 0 von Willebrand factor type A domain RA PF00788.23 CBY41025.1 - 1.1e-09 38.8 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 CBY41025.1 - 1.3e-07 32.0 0.2 2.6e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 PH domain DNA_pol_E_B PF04042.16 CBY41028.1 - 1.5e-13 50.6 0.2 2e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RmlD_sub_bind PF04321.17 CBY41029.1 - 0.043 12.9 0.0 0.049 12.7 0.0 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain ATP_Ca_trans_C PF12424.8 CBY41030.1 - 9e-23 80.5 0.6 1.4e-22 79.9 0.6 1.3 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal EMP70 PF02990.16 CBY41033.1 - 7e-208 691.5 17.7 8.3e-208 691.2 17.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Phage_holin_3_6 PF07332.11 CBY41033.1 - 2.7 8.0 0.0 2.7 8.0 0.0 4.5 3 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Cys_rich_FGFR PF00839.17 CBY41034.1 - 4.1e-53 177.4 27.3 4.9e-13 49.0 1.2 5.1 5 0 0 5 5 5 5 Cysteine rich repeat PGK PF00162.19 CBY41034.1 - 0.08 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoglycerate kinase GAS PF13851.6 CBY41037.1 - 0.012 14.9 61.8 0.27 10.6 7.8 4.6 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3618 PF12277.8 CBY41037.1 - 0.051 13.8 1.9 0.2 12.0 1.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Pox_A_type_inc PF04508.12 CBY41037.1 - 0.31 11.0 11.4 8.1 6.5 0.0 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat FUSC PF04632.12 CBY41037.1 - 1.9 6.9 7.6 2.8 6.4 7.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 CBY41037.1 - 5.6 7.3 16.1 1.1 9.5 2.3 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) COBRA1 PF06209.13 CBY41038.1 - 0.0017 17.3 0.0 0.0019 17.2 0.0 1.0 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) DUF1192 PF06698.11 CBY41038.1 - 0.022 14.8 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4164 PF13747.6 CBY41038.1 - 0.058 13.7 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 CBY41038.1 - 0.072 13.2 0.2 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 IL22 PF14565.6 CBY41038.1 - 0.1 12.8 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor BTB PF00651.31 CBY41040.1 - 1e-10 41.8 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF4533 PF15047.6 CBY41041.1 - 0.0008 19.0 2.7 0.0013 18.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4533) DHFR_1 PF00186.19 CBY41041.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrofolate reductase RVT_1 PF00078.27 CBY41042.1 - 8.8e-10 38.5 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.11 CBY41042.1 - 0.0036 16.9 0.0 0.015 14.9 0.0 2.0 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) UPF0182 PF03699.13 CBY41043.1 - 2.4 6.2 5.0 2.8 6.0 5.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) EPL1 PF10513.9 CBY41044.1 - 0.023 15.1 4.3 0.034 14.6 4.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like SirA PF10747.9 CBY41044.1 - 0.12 12.7 5.0 0.12 12.7 2.2 2.3 1 1 1 2 2 2 0 Sporulation inhibitor of replication protein SirA PDZ PF00595.24 CBY41045.1 - 2.4e-13 50.2 0.1 2.8e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY41045.1 - 2.4e-12 46.5 1.0 4.1e-10 39.3 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY41045.1 - 3.5e-10 40.1 1.3 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 PDZ domain MMR_HSR1_Xtn PF16897.5 CBY41045.1 - 0.0096 15.9 0.1 0.11 12.5 0.1 2.1 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain GRASP55_65 PF04495.14 CBY41045.1 - 0.14 12.5 0.0 0.46 10.8 0.0 1.7 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 CBY41045.1 - 0.16 11.9 0.3 0.38 10.8 0.1 1.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain SNARE_assoc PF09335.11 CBY41046.1 - 0.0081 16.6 0.3 0.012 16.1 0.3 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein Gly-zipper_Omp PF13488.6 CBY41046.1 - 0.011 15.7 14.0 0.022 14.7 14.0 1.5 1 0 0 1 1 1 0 Glycine zipper DUF456 PF04306.13 CBY41046.1 - 0.017 15.4 8.5 0.024 14.9 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 CBY41046.1 - 1.9 8.4 17.7 3.7 7.5 17.7 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Frag1 PF10277.9 CBY41047.1 - 4e-27 95.2 10.0 4.9e-27 94.9 10.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CBM_14 PF01607.24 CBY41048.1 - 1.2e-11 44.6 7.5 5.9e-11 42.4 6.7 2.1 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Kelch_6 PF13964.6 CBY41050.1 - 0.058 13.7 4.8 6 7.3 0.1 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.15 CBY41050.1 - 1.2 9.2 4.6 3.4 7.8 0.3 3.3 3 1 1 4 4 4 0 Kelch motif Dmrt1 PF12374.8 CBY41052.1 - 8.8 6.9 10.5 1.7 9.1 6.7 1.8 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 ThiJ_like PF17124.5 CBY41053.1 - 0.067 12.9 0.7 1 9.0 0.0 2.1 1 1 1 2 2 2 0 ThiJ/PfpI family-like AAA_14 PF13173.6 CBY41054.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain PRCC PF10253.9 CBY41055.1 - 1.4e-27 97.9 0.3 1.4e-27 97.9 0.3 3.3 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2462 PF09495.10 CBY41056.1 - 1.2e-11 45.1 17.6 1.4e-11 44.9 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) WD40 PF00400.32 CBY41057.1 - 4e-06 27.5 0.2 0.00033 21.4 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Abhydrolase_3 PF07859.13 CBY41058.1 - 1.4e-20 74.1 0.0 1.4e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY41058.1 - 0.0002 20.9 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 CBY41058.1 - 0.0094 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.7 CBY41058.1 - 0.014 14.3 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CBY41058.1 - 0.025 13.9 0.0 0.027 13.8 0.0 1.0 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CBY41058.1 - 0.068 13.0 0.0 0.068 13.0 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase YjeF_N PF03853.15 CBY41058.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 YjeF-related protein N-terminus AXE1 PF05448.12 CBY41058.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Enkurin PF13864.6 CBY41059.1 - 0.013 15.9 5.1 0.013 15.9 5.1 2.8 3 0 0 3 3 3 0 Calmodulin-binding ATG16 PF08614.11 CBY41059.1 - 0.051 13.8 8.8 0.06 13.6 2.8 2.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1843 PF08898.10 CBY41059.1 - 0.11 13.1 3.3 0.18 12.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Mito_carr PF00153.27 CBY41060.1 - 8.2e-17 60.9 0.2 9.7e-17 60.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein PAP2 PF01569.21 CBY41061.1 - 1.3e-08 34.7 0.2 2.2e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily Amastin PF07344.11 CBY41061.1 - 0.039 13.8 1.7 0.56 10.0 1.7 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein Peptidase_M19 PF01244.21 CBY41063.1 - 1.3e-64 218.4 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) BAAT_C PF08840.11 CBY41064.1 - 9.5e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CBY41064.1 - 0.013 15.0 0.2 0.35 10.4 0.2 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Sulfatase PF00884.23 CBY41065.1 - 1e-31 110.5 0.1 1.3e-31 110.2 0.1 1.1 1 0 0 1 1 1 1 Sulfatase BAAT_C PF08840.11 CBY41067.1 - 9.8e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CBY41067.1 - 0.013 15.0 0.2 0.35 10.4 0.2 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_M19 PF01244.21 CBY41068.1 - 2.7e-80 269.9 0.0 1.1e-79 268.0 0.0 1.9 2 1 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Adaptin_N PF01602.20 CBY41070.1 - 4.2e-134 448.0 9.5 5.5e-134 447.6 9.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CBY41070.1 - 6.8e-27 93.9 0.0 1.7e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CBY41070.1 - 3.4e-11 43.4 0.5 1.2e-10 41.7 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 CBY41070.1 - 3.8e-06 27.0 0.9 0.00071 19.6 0.0 3.2 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY41070.1 - 4.3e-05 23.8 4.3 0.00013 22.3 0.6 3.5 2 2 1 3 3 3 1 HEAT repeats HEAT PF02985.22 CBY41070.1 - 0.0025 17.9 1.7 32 5.1 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat DRIM PF07539.12 CBY41070.1 - 0.0072 14.7 3.7 0.064 11.5 1.9 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis B2-adapt-app_C PF09066.10 CBY41070.1 - 0.049 13.7 0.0 0.16 12.1 0.0 2.0 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain His_Phos_1 PF00300.22 CBY41072.1 - 6.6e-30 104.3 0.0 7.9e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FEZ PF07763.13 CBY41073.1 - 0.0012 18.7 0.2 0.0014 18.4 0.2 1.1 1 0 0 1 1 1 1 FEZ-like protein FAS_N PF17828.1 CBY41073.1 - 0.087 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta ETF_alpha PF00766.19 CBY41074.1 - 7.2e-34 115.7 1.1 1e-33 115.2 0.5 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CBY41074.1 - 7.9e-20 71.5 0.9 1.4e-19 70.7 0.1 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain PT-VENN PF04829.13 CBY41074.1 - 0.092 12.8 0.1 0.3 11.2 0.1 1.9 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif CSD PF00313.22 CBY41075.1 - 2.9e-25 87.9 1.6 2.9e-25 87.9 1.6 1.6 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CBY41075.1 - 0.0018 17.9 0.0 0.0083 15.8 0.0 2.2 1 0 0 1 1 1 1 Ribonuclease B OB domain SRP-alpha_N PF04086.13 CBY41075.1 - 5.7 6.8 13.8 7.7 6.3 13.8 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SEP PF08059.13 CBY41076.1 - 0.047 14.3 0.1 0.14 12.7 0.1 1.8 1 0 0 1 1 1 0 SEP domain SR-25 PF10500.9 CBY41076.1 - 0.34 10.5 25.0 0.032 13.8 13.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PQ-loop PF04193.14 CBY41077.1 - 2.3e-27 94.5 13.7 6.9e-15 54.6 4.7 3.2 2 1 0 3 3 3 2 PQ loop repeat Chromo PF00385.24 CBY41078.1 - 6.7e-30 102.8 3.3 5.1e-11 42.3 0.3 3.8 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 CBY41078.1 - 0.0013 18.6 4.6 0.016 15.1 0.0 2.9 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain DUF1918 PF08940.11 CBY41078.1 - 0.072 12.7 0.9 6.2 6.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) DDHD PF02862.17 CBY41078.1 - 5.7 7.0 14.3 0.44 10.7 5.7 2.3 2 1 0 2 2 2 0 DDHD domain Sulfotransfer_2 PF03567.14 CBY41079.1 - 4.6e-17 62.8 0.3 6.3e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY41079.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Ets PF00178.22 CBY41081.1 - 4.6e-36 123.2 3.7 5.8e-36 122.8 3.7 1.1 1 0 0 1 1 1 1 Ets-domain MgsA_C PF12002.8 CBY41081.1 - 0.041 13.8 0.0 0.05 13.5 0.0 1.0 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal HSF_DNA-bind PF00447.17 CBY41081.1 - 0.044 14.4 1.0 0.062 13.9 1.0 1.3 1 0 0 1 1 1 0 HSF-type DNA-binding OrfB_IS605 PF01385.19 CBY41081.1 - 0.07 13.4 0.4 0.19 11.9 0.2 1.8 2 0 0 2 2 2 0 Probable transposase RasGEF PF00617.19 CBY41083.1 - 5.2e-43 147.3 0.3 7.4e-42 143.5 0.0 2.1 1 1 1 2 2 2 1 RasGEF domain PH PF00169.29 CBY41083.1 - 7.1e-05 23.3 0.2 0.00012 22.5 0.2 1.4 1 0 0 1 1 1 1 PH domain EGF_CA PF07645.15 CBY41084.1 - 1.1e-08 35.2 3.7 1.1e-08 35.2 3.7 2.7 2 1 0 2 2 2 1 Calcium-binding EGF domain cEGF PF12662.7 CBY41084.1 - 2.7e-06 27.2 0.7 7e-06 25.9 0.7 1.7 1 0 0 1 1 1 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 CBY41084.1 - 1.1 9.4 12.5 0.32 11.1 2.9 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 DUF2850 PF11012.8 CBY41085.1 - 0.051 13.9 0.1 0.12 12.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2850) Glycos_transf_2 PF00535.26 CBY41086.1 - 3.7e-16 59.4 0.1 7.3e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 FWWh PF14922.6 CBY41089.1 - 2e-35 121.9 0.6 3.6e-35 121.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function HisKA PF00512.25 CBY41089.1 - 0.21 11.6 1.2 0.66 10.1 0.0 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain HU-DNA_bdg PF14848.6 CBY41089.1 - 0.88 9.6 4.1 24 4.9 0.1 3.1 3 0 0 3 3 3 0 DNA-binding domain ER_lumen_recept PF00810.18 CBY41090.1 - 3.5e-54 183.6 8.0 3.5e-54 183.6 8.0 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY41090.1 - 0.0022 17.7 9.3 0.19 11.5 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat ATP-grasp_2 PF08442.10 CBY41091.1 - 1.9e-16 60.2 0.0 2.2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 CBY41091.1 - 7.9e-06 25.5 0.0 9.4e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CBY41091.1 - 9.4e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 CBY41091.1 - 0.055 13.0 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain CH PF00307.31 CBY41092.1 - 2e-15 56.9 0.1 3.9e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Smoothelin PF12510.8 CBY41092.1 - 9e-11 41.6 2.7 2.6e-10 40.2 2.7 1.8 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein CAMSAP_CH PF11971.8 CBY41092.1 - 2.2e-06 27.4 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain GED PF02212.18 CBY41092.1 - 0.096 12.9 0.7 0.25 11.5 0.7 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain GREB1 PF15782.5 CBY41092.1 - 4 4.4 17.9 5.1 4.1 17.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCCH PF00642.24 CBY41095.1 - 0.00044 20.1 2.3 0.0011 18.9 2.3 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY41095.1 - 0.00049 20.1 2.0 0.00049 20.1 2.0 2.6 4 0 0 4 4 4 1 Zinc finger domain Torus PF16131.5 CBY41095.1 - 0.0026 18.5 0.3 0.0063 17.2 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 CBY41095.1 - 0.032 14.0 2.0 0.073 12.9 2.0 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger dsrm PF00035.26 CBY41096.1 - 8.5e-20 71.2 19.2 4.3e-09 37.0 0.7 4.1 4 0 0 4 4 4 3 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY41096.1 - 4.7e-11 42.7 5.8 0.0042 17.2 0.2 4.1 4 0 0 4 4 4 3 Dicer dimerisation domain DZF PF07528.14 CBY41096.1 - 3.1e-07 30.3 0.0 0.0022 17.7 0.0 2.7 1 1 1 2 2 2 2 DZF domain BTB PF00651.31 CBY41098.1 - 8.6e-06 26.0 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Yos1 PF08571.10 CBY41099.1 - 9.8e-28 96.2 0.2 1.1e-27 96.1 0.2 1.0 1 0 0 1 1 1 1 Yos1-like DUF2127 PF09900.9 CBY41099.1 - 0.14 12.4 4.9 0.2 11.9 1.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) TRP PF06011.12 CBY41099.1 - 10 4.7 7.7 4.9 5.8 0.8 2.0 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Methyltr_RsmB-F PF01189.17 CBY41100.1 - 0.049 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Lung_7-TM_R PF06814.13 CBY41101.1 - 7.7e-17 61.5 7.3 9.1e-17 61.2 7.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.6 CBY41101.1 - 0.00013 22.5 1.9 0.00021 21.8 1.9 1.3 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DUF3671 PF12420.8 CBY41101.1 - 0.014 15.5 1.1 0.023 14.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function K_trans PF02705.16 CBY41101.1 - 0.042 12.4 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter Adap_comp_sub PF00928.21 CBY41102.1 - 4.8e-91 304.8 0.1 6.9e-91 304.3 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBY41102.1 - 3.3e-07 30.3 2.1 6e-07 29.5 2.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBY41102.1 - 0.0043 16.5 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mito_carr PF00153.27 CBY41103.1 - 2.3e-44 149.2 6.9 1.2e-17 63.5 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Snurportin1 PF11538.8 CBY41104.1 - 0.0083 16.3 4.8 0.019 15.1 4.8 1.6 1 0 0 1 1 1 1 Snurportin1 Sporozoite_P67 PF05642.11 CBY41105.1 - 0.18 9.9 3.7 0.2 9.7 3.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 CBY41105.1 - 0.34 10.8 2.3 0.7 9.8 2.3 1.6 1 1 0 1 1 1 0 TMEM154 protein family Mucin PF01456.17 CBY41105.1 - 1.1 9.2 14.1 1.6 8.7 14.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein UcrQ PF02939.16 CBY41106.1 - 1.2e-08 34.7 1.1 1.7e-08 34.3 1.1 1.4 1 1 0 1 1 1 1 UcrQ family Ank_2 PF12796.7 CBY41107.1 - 1.2e-32 112.3 0.9 6.5e-13 49.1 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY41107.1 - 7.6e-30 102.9 2.8 6.4e-10 39.4 0.0 5.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY41107.1 - 1.2e-21 76.5 0.3 5.1e-05 23.5 0.0 5.1 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBY41107.1 - 7.3e-20 70.5 1.6 0.0013 19.1 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 CBY41107.1 - 1.1e-18 65.3 2.8 0.007 16.8 0.1 8.0 8 0 0 8 8 8 4 Ankyrin repeat Polysacc_deac_1 PF01522.21 CBY41107.1 - 0.16 11.8 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide deacetylase FAD_binding_3 PF01494.19 CBY41108.1 - 1.9e-17 63.6 0.0 4.9e-08 32.6 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CBY41108.1 - 0.045 14.0 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 CBY41108.1 - 0.16 11.0 0.0 0.42 9.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Kelch_6 PF13964.6 CBY41109.1 - 4.9e-14 52.0 7.0 0.0011 19.2 0.0 6.2 3 2 3 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CBY41109.1 - 6.6e-12 44.8 19.2 1.4e-06 27.7 0.0 7.4 7 2 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBY41109.1 - 3.4e-10 39.5 4.7 0.028 14.4 0.0 5.8 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CBY41109.1 - 4.2e-07 29.9 0.5 0.14 12.1 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY41109.1 - 8.6e-05 22.7 0.1 9.5 6.6 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY41109.1 - 0.0071 16.3 7.0 0.45 10.6 0.0 4.4 6 0 0 6 6 6 2 Kelch motif EF-hand_6 PF13405.6 CBY41110.1 - 0.00077 19.2 0.5 0.0017 18.1 0.3 1.8 1 1 0 1 1 1 1 EF-hand domain CAAP1 PF15335.6 CBY41110.1 - 0.036 14.6 0.1 0.049 14.2 0.1 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 TERB2 PF15101.6 CBY41110.1 - 0.049 13.7 0.0 0.051 13.6 0.0 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cas9_a PF18470.1 CBY41110.1 - 0.094 12.2 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain EF-hand_7 PF13499.6 CBY41110.1 - 0.14 12.6 2.1 0.25 11.8 0.4 1.9 1 1 0 1 1 1 0 EF-hand domain pair RasGAP PF00616.19 CBY41111.1 - 0.038 13.7 6.4 0.098 12.4 6.1 1.7 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF2664 PF10867.8 CBY41111.1 - 0.065 13.7 3.5 0.15 12.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DDHD PF02862.17 CBY41111.1 - 0.24 11.5 3.9 0.26 11.4 3.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF4600 PF15372.6 CBY41111.1 - 0.78 10.2 13.8 1.1 9.7 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Selenoprotein_S PF06936.11 CBY41111.1 - 3 7.6 12.7 4.6 7.0 12.7 1.3 1 1 0 1 1 1 0 Selenoprotein S (SelS) GAS PF13851.6 CBY41112.1 - 0.0031 16.9 53.6 0.02 14.2 15.5 4.4 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 CBY41112.1 - 0.029 14.7 6.2 0.029 14.7 6.2 7.0 3 2 4 8 8 8 0 Csm1 N-terminal domain bZIP_2 PF07716.15 CBY41112.1 - 0.094 12.8 0.6 0.094 12.8 0.6 8.0 8 1 2 10 10 10 0 Basic region leucine zipper DUF4989 PF16379.5 CBY41112.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) FRB_dom PF08771.11 CBY41112.1 - 0.63 10.5 6.5 0.42 11.0 2.9 2.6 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Fez1 PF06818.15 CBY41112.1 - 4.9 7.6 51.0 0.75 10.2 22.1 3.7 1 1 3 4 4 4 0 Fez1 eIF-1a PF01176.19 CBY41113.1 - 2.5e-12 46.4 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TSA PF03249.13 CBY41113.1 - 0.11 11.2 1.4 0.13 11.0 1.4 1.1 1 0 0 1 1 1 0 Type specific antigen DNA_pol_phi PF04931.13 CBY41113.1 - 2.4 6.1 8.2 3.2 5.7 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 CBY41114.1 - 3.8e-25 88.8 0.0 5.8e-25 88.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41114.1 - 1.1e-10 41.3 0.0 1.7e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY41114.1 - 0.00035 19.5 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBY41114.1 - 0.00037 20.5 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY41114.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY41114.1 - 0.0063 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBY41114.1 - 0.07 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain XendoU PF09412.10 CBY41115.1 - 6.1e-83 278.1 0.0 6.9e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU EndoU_bacteria PF14436.6 CBY41115.1 - 0.0022 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial EndoU nuclease Radial_spoke PF04712.12 CBY41116.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein B277 PF17623.2 CBY41119.1 - 0.13 11.3 2.0 0.24 10.4 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Sushi PF00084.20 CBY41120.1 - 0.12 12.9 1.2 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) DUF5316 PF17247.2 CBY41120.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Galactosyl_T PF01762.21 CBY41121.1 - 4.9e-21 75.4 0.0 8.5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase DDE_Tnp_2 PF04693.12 CBY41121.1 - 0.04 13.2 0.8 0.062 12.5 0.8 1.2 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 EMC3_TMCO1 PF01956.16 CBY41121.1 - 6.6 6.4 7.2 7.3 6.3 6.0 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like OxoGdeHyase_C PF16870.5 CBY41122.1 - 4.8e-52 175.7 0.0 6e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 CBY41122.1 - 3.3e-15 56.2 0.0 1.1e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain DNA_pol_B_palm PF14792.6 CBY41123.1 - 0.069 13.4 0.3 0.15 12.3 0.3 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm RNase_T PF00929.24 CBY41126.1 - 6.1e-05 23.6 1.1 0.00043 20.9 0.1 2.2 2 1 0 2 2 2 1 Exonuclease Tetraspanin PF00335.20 CBY41127.1 - 0.021 14.5 8.3 0.03 14.0 8.3 1.3 1 1 0 1 1 1 0 Tetraspanin family Vma12 PF11712.8 CBY41127.1 - 9.6 6.3 7.6 2.3 8.3 4.3 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase VWA PF00092.28 CBY41128.1 - 3.8e-39 134.7 0.0 6.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY41128.1 - 2.6e-16 60.2 0.0 7.8e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 CBY41128.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 CBY41128.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain rRNA_proc-arch PF13234.6 CBY41129.1 - 2.4e-74 250.7 1.9 4.7e-74 249.7 0.3 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CBY41129.1 - 8.5e-54 181.6 1.3 1.9e-53 180.5 1.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain HTH_43 PF09904.9 CBY41129.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix CENP-F_leu_zip PF10473.9 CBY41129.1 - 0.2 11.6 7.4 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HisKA PF00512.25 CBY41129.1 - 0.27 11.3 1.7 19 5.4 0.0 3.3 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Kinesin PF00225.23 CBY41130.1 - 2.1e-36 125.5 1.7 2e-35 122.3 1.7 2.4 1 1 0 1 1 1 1 Kinesin motor domain MAPEG PF01124.18 CBY41130.1 - 7.4e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 MAPEG family Microtub_bd PF16796.5 CBY41130.1 - 2.3e-11 43.8 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Phospholip_A2_1 PF00068.19 CBY41131.1 - 2.9e-05 24.5 0.0 2.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase A2 SOG2 PF10428.9 CBY41131.1 - 2.6 7.2 28.5 3 7.0 28.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2970 PF11174.8 CBY41132.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) zf-RING_UBOX PF13445.6 CBY41133.1 - 3.1e-06 27.1 5.3 5.6e-06 26.3 5.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY41133.1 - 1.1e-05 25.6 9.0 2.3e-05 24.6 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY41133.1 - 0.00021 21.1 10.9 0.00081 19.2 11.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY41133.1 - 0.00064 19.6 11.2 0.0021 18.0 11.5 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY41133.1 - 0.0011 18.8 12.3 0.0064 16.3 12.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY41133.1 - 0.0018 18.1 5.7 0.0033 17.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY41133.1 - 0.0024 17.7 11.0 0.0068 16.2 11.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CBY41133.1 - 0.011 15.4 5.8 0.014 14.9 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fusion_gly PF00523.18 CBY41133.1 - 0.031 12.6 2.7 0.043 12.1 2.7 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 IBR PF01485.21 CBY41133.1 - 0.038 14.2 7.0 0.08 13.2 7.0 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 CBY41133.1 - 0.047 13.5 7.2 0.11 12.3 7.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SUKH-3 PF14433.6 CBY41133.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 SUKH-3 immunity protein Golgin_A5 PF09787.9 CBY41133.1 - 0.17 11.3 16.6 0.24 10.8 16.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Macoilin PF09726.9 CBY41133.1 - 0.18 10.3 7.3 0.19 10.3 7.3 1.1 1 0 0 1 1 1 0 Macoilin family Prok-RING_4 PF14447.6 CBY41133.1 - 0.24 11.3 12.7 17 5.4 13.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YojJ PF10372.9 CBY41133.1 - 0.25 11.5 5.0 0.68 10.1 1.0 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus zf-C3HC4_4 PF15227.6 CBY41133.1 - 0.34 11.1 7.0 2.7 8.2 7.0 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Enkurin PF13864.6 CBY41133.1 - 0.64 10.5 14.2 0.045 14.2 5.2 2.7 1 1 1 2 2 2 0 Calmodulin-binding Matrilin_ccoil PF10393.9 CBY41133.1 - 0.68 9.8 4.7 0.17 11.7 0.9 2.1 2 0 0 2 2 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Sulfatase_C PF14707.6 CBY41133.1 - 0.7 10.6 6.6 0.85 10.4 0.6 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Mqo PF06039.15 CBY41133.1 - 0.72 8.3 3.6 0.93 8.0 3.6 1.0 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) V_ATPase_I PF01496.19 CBY41133.1 - 1.2 7.0 8.0 1.4 6.8 8.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2703 PF10865.8 CBY41133.1 - 1.3 9.3 8.1 0.42 10.8 4.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Spc7 PF08317.11 CBY41133.1 - 2.1 7.1 16.3 3.2 6.6 16.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBY41133.1 - 3.6 8.0 14.3 30 5.0 14.3 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Baculo_IE-1 PF05290.11 CBY41133.1 - 6.3 6.7 12.4 88 3.0 12.4 2.2 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Aa_trans PF01490.18 CBY41134.1 - 1.5e-74 251.2 16.1 1.5e-60 205.1 11.8 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein PC_rep PF01851.22 CBY41136.1 - 1e-29 101.4 8.5 3.5e-07 30.3 0.1 6.6 6 0 0 6 6 6 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBY41136.1 - 6e-11 42.6 5.4 0.0019 18.5 0.0 4.7 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CBY41136.1 - 0.0006 19.9 0.3 3.9 8.0 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat ATP_bind_1 PF03029.17 CBY41137.1 - 5.3e-76 255.6 0.5 6.8e-76 255.2 0.5 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein cobW PF02492.19 CBY41137.1 - 1.3e-05 24.8 0.5 0.00036 20.2 0.5 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBY41137.1 - 2.2e-05 24.4 0.1 0.19 11.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CBY41137.1 - 5e-05 23.4 0.0 0.00065 19.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CBY41137.1 - 7.7e-05 22.9 0.2 0.00031 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CBY41137.1 - 0.00019 21.0 0.0 0.0043 16.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBY41137.1 - 0.00075 19.1 0.2 0.028 13.9 0.0 2.5 3 0 0 3 3 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBY41137.1 - 0.0008 18.5 0.0 0.66 8.9 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CBY41137.1 - 0.00086 19.7 0.2 0.0053 17.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CBY41137.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CBY41137.1 - 0.0013 19.0 0.0 0.0056 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBY41137.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 CBY41137.1 - 0.0014 18.5 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 NTPase TsaE PF02367.17 CBY41137.1 - 0.0016 18.5 0.1 0.0085 16.1 0.0 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CBY41137.1 - 0.0016 19.0 0.8 0.008 16.7 0.0 2.4 3 0 0 3 3 1 1 AAA domain Gtr1_RagA PF04670.12 CBY41137.1 - 0.0027 17.1 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 CBY41137.1 - 0.0029 17.5 0.0 0.057 13.2 0.0 2.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 CBY41137.1 - 0.0046 17.1 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain SRP54 PF00448.22 CBY41137.1 - 0.0048 16.6 0.0 0.065 12.9 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Arf PF00025.21 CBY41137.1 - 0.0095 15.4 0.1 0.87 9.0 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family DMAP1 PF05499.12 CBY41137.1 - 0.012 15.5 0.9 0.021 14.7 0.9 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) FtsK_SpoIIIE PF01580.18 CBY41137.1 - 0.025 13.9 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 CBY41137.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CBY41137.1 - 0.033 13.4 0.0 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 CBY41137.1 - 0.035 13.3 0.9 1.7 7.7 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.9 CBY41137.1 - 0.038 13.7 0.3 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 CBY41137.1 - 0.043 13.8 0.3 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 CBY41137.1 - 0.046 13.1 0.1 0.88 9.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit BshC PF10079.9 CBY41137.1 - 0.051 12.3 0.2 0.08 11.7 0.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Viral_helicase1 PF01443.18 CBY41137.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CBY41137.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY41137.1 - 0.065 13.6 0.0 0.72 10.3 0.0 2.5 2 1 0 2 2 2 0 RNA helicase Ras PF00071.22 CBY41137.1 - 0.078 12.6 0.0 3.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Ras family Zeta_toxin PF06414.12 CBY41137.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 CBY41137.1 - 0.11 12.2 0.9 1.6 8.4 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 CBY41137.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBY41137.1 - 1.4 8.9 4.7 5.7 7.0 0.1 3.3 2 2 0 2 2 2 0 Dynamin family MCM PF00493.23 CBY41138.1 - 5e-94 313.6 0.0 6.8e-94 313.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBY41138.1 - 6e-29 100.3 0.0 1.3e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CBY41138.1 - 1.5e-06 28.1 0.1 3.1e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CBY41138.1 - 5.6e-06 25.9 0.0 0.00094 18.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY41138.1 - 0.00013 22.0 0.0 0.00038 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY41138.1 - 0.0012 18.7 0.0 0.0044 16.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBY41138.1 - 0.0042 16.8 0.1 0.11 12.2 0.0 2.6 3 0 0 3 3 3 1 Sigma-54 interaction domain FF PF01846.19 CBY41139.1 - 4.1e-37 126.1 48.0 1.2e-11 44.6 5.3 6.5 6 0 0 6 6 6 5 FF domain WW PF00397.26 CBY41139.1 - 7.8e-13 48.3 5.1 2.2e-06 27.6 0.3 3.0 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 CBY41139.1 - 4.4e-06 27.3 14.6 0.00032 21.3 1.7 4.4 2 1 1 3 3 3 2 p190-A and -B Rho GAPs FF domain zf-MYND PF01753.18 CBY41141.1 - 2.6e-05 24.2 16.0 2.6e-05 24.2 16.0 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CBY41141.1 - 0.0061 16.6 8.5 0.013 15.5 8.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Tau95_N PF17682.1 CBY41141.1 - 0.068 13.4 1.0 0.3 11.3 1.0 2.1 1 1 0 1 1 1 0 Tau95 Triple barrel domain CR6_interact PF10147.9 CBY41143.1 - 7.5e-11 42.1 17.3 4.6e-10 39.6 17.3 1.9 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Forkhead PF00250.18 CBY41144.1 - 5.3e-39 132.4 0.0 8.6e-39 131.7 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Laminin_N PF00055.17 CBY41146.1 - 3.2e-39 134.9 0.0 3.2e-39 134.9 0.0 3.1 2 1 2 4 4 4 1 Laminin N-terminal (Domain VI) Laminin_EGF PF00053.24 CBY41146.1 - 3.9e-17 62.1 55.1 1.2e-06 28.6 13.2 3.7 3 0 0 3 3 3 3 Laminin EGF domain NTR PF01759.21 CBY41146.1 - 1.1e-08 34.8 9.5 2.7e-06 27.1 0.8 2.6 1 1 1 2 2 2 2 UNC-6/NTR/C345C module DUF1192 PF06698.11 CBY41147.1 - 0.00034 20.6 2.3 0.00034 20.6 2.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1192) Emaravirus_P4 PF16505.5 CBY41147.1 - 8 5.4 14.5 0.36 9.8 3.0 3.0 3 0 0 3 3 3 0 P4 movement protein of Emaravirus, and the 30K superfamily Vps51 PF08700.11 CBY41147.1 - 9.8 6.3 16.6 0.12 12.5 3.2 3.9 3 2 0 3 3 3 0 Vps51/Vps67 Lipase PF00151.19 CBY41148.1 - 1.2e-40 139.8 0.7 2.7e-40 138.7 0.7 1.6 1 1 0 1 1 1 1 Lipase Abhydrolase_6 PF12697.7 CBY41148.1 - 0.00076 20.1 0.1 0.00087 20.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY41148.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 CBY41148.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 CBY41148.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY41148.1 - 0.085 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 CBY41148.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) rve PF00665.26 CBY41149.1 - 2.7e-14 53.4 0.0 3.9e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CBY41150.1 - 7.2e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 CBY41150.1 - 0.00099 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain FCH PF00611.23 CBY41151.1 - 0.034 14.4 0.2 0.096 13.0 0.2 1.8 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain adh_short PF00106.25 CBY41152.1 - 2.5e-09 36.9 0.0 3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY41152.1 - 3.7e-05 23.4 0.1 4.7e-05 23.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY41152.1 - 0.00089 19.2 0.1 0.0016 18.4 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CBY41152.1 - 0.0017 18.3 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CBY41152.1 - 0.0035 16.5 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CBY41152.1 - 0.0099 15.4 0.0 0.011 15.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family MCU PF04678.13 CBY41153.1 - 6.5e-44 150.1 2.0 8.8e-44 149.7 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter adh_short PF00106.25 CBY41154.1 - 9e-27 93.8 0.0 1.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY41154.1 - 7.8e-11 42.0 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY41154.1 - 5.4e-05 23.2 0.0 0.086 12.8 0.1 2.2 2 0 0 2 2 2 2 KR domain DUF3236 PF11576.8 CBY41154.1 - 0.048 13.4 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) DUF2358 PF10184.9 CBY41155.1 - 6.1e-06 26.5 0.0 8.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DUF4416 PF14385.6 CBY41156.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) HP_OMP PF01856.17 CBY41156.1 - 0.097 12.7 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Helicobacter outer membrane protein Mce4_CUP1 PF11887.8 CBY41157.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Gal_Lectin PF02140.18 CBY41158.1 - 2.4e-14 53.5 2.1 4e-14 52.8 0.1 2.4 2 0 0 2 2 2 1 Galactose binding lectin domain Chlam_PMP PF02415.17 CBY41158.1 - 0.041 14.4 0.5 0.47 11.0 0.0 2.8 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Lectin_C PF00059.21 CBY41160.1 - 3.5e-30 104.9 25.8 1.2e-08 35.6 6.9 5.7 5 1 1 6 6 6 5 Lectin C-type domain UL45 PF05473.12 CBY41160.1 - 0.47 10.1 3.5 18 4.9 0.1 3.5 3 1 0 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like ZapB PF06005.12 CBY41162.1 - 0.0055 17.1 0.1 0.0086 16.5 0.1 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 CBY41162.1 - 0.0093 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator CCDC144C PF14915.6 CBY41162.1 - 0.01 15.0 0.0 0.011 14.9 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region APC_N_CC PF16689.5 CBY41162.1 - 0.012 15.6 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain HALZ PF02183.18 CBY41162.1 - 0.017 15.3 0.5 0.032 14.5 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4200 PF13863.6 CBY41162.1 - 0.032 14.6 0.1 0.043 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.20 CBY41162.1 - 0.043 13.8 0.3 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit YscO PF07321.12 CBY41162.1 - 0.046 13.7 0.2 0.061 13.3 0.2 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO Spc24 PF08286.11 CBY41162.1 - 0.064 13.5 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HMMR_C PF15908.5 CBY41162.1 - 0.069 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal LPP PF04728.13 CBY41162.1 - 0.094 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper SR-25 PF10500.9 CBY41163.1 - 0.53 9.9 14.4 0.77 9.3 14.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 CBY41163.1 - 1.1 7.3 7.0 1.4 7.0 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LSM PF01423.22 CBY41164.1 - 1.2e-19 69.8 0.6 1.6e-19 69.3 0.6 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CBY41164.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Hfq protein DUF2733 PF10813.8 CBY41165.1 - 0.00093 18.9 1.4 0.00094 18.9 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2733) Lectin_C PF00059.21 CBY41166.1 - 3.3e-17 63.2 4.9 4.6e-08 33.8 0.0 3.6 3 1 0 3 3 3 3 Lectin C-type domain UL45 PF05473.12 CBY41166.1 - 0.19 11.4 0.2 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Lectin_C PF00059.21 CBY41167.1 - 2.2e-11 44.5 0.0 3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain DUF3762 PF12591.8 CBY41167.1 - 0.059 13.6 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) PABP PF00658.18 CBY41168.1 - 1e-26 92.9 0.2 1.4e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain HTH_9 PF08221.11 CBY41168.1 - 0.18 12.0 0.1 0.28 11.3 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RRM_1 PF00076.22 CBY41169.1 - 6.6e-11 41.9 0.6 1.4e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CBY41169.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain EGF_CA PF07645.15 CBY41170.1 - 2.8e-132 430.7 358.6 2e-10 40.7 10.6 22.0 21 1 1 22 22 22 19 Calcium-binding EGF domain EGF_3 PF12947.7 CBY41170.1 - 3.2e-75 248.0 298.6 1.7e-11 44.1 9.8 23.1 20 3 2 22 22 22 17 EGF domain cEGF PF12662.7 CBY41170.1 - 3.4e-67 221.9 220.4 2.4e-05 24.1 3.3 22.5 22 0 0 22 22 22 20 Complement Clr-like EGF-like EGF PF00008.27 CBY41170.1 - 7.8e-23 80.4 287.8 1.9e-05 24.8 5.9 23.4 22 1 0 22 22 22 15 EGF-like domain FXa_inhibition PF14670.6 CBY41170.1 - 9.5e-21 73.8 291.4 0.0031 17.7 8.5 23.1 14 6 8 22 22 22 15 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY41170.1 - 1.4e-07 31.4 273.0 0.012 15.7 7.9 21.8 21 1 1 22 22 22 15 MSP1 EGF domain 1 hEGF PF12661.7 CBY41170.1 - 6.1e-06 26.7 286.1 0.013 16.1 2.3 26.8 29 0 0 29 29 29 17 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 CBY41170.1 - 0.017 15.4 7.1 0.017 15.4 7.1 21.8 21 1 1 22 22 22 0 Pvs28 EGF domain Fe_bilin_red PF05996.12 CBY41171.1 - 0.041 13.6 0.9 0.052 13.2 0.8 1.3 1 1 0 1 1 1 0 Ferredoxin-dependent bilin reductase CmlA_N PF18456.1 CBY41171.1 - 0.068 12.5 0.1 0.075 12.3 0.1 1.1 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Pkinase PF00069.25 CBY41172.1 - 1.8e-09 37.3 0.4 6.1e-09 35.6 0.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41172.1 - 3e-08 33.3 0.0 1.2e-07 31.3 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Methyltransf_31 PF13847.6 CBY41172.1 - 0.12 12.2 1.6 0.12 12.2 0.3 1.6 2 0 0 2 2 2 0 Methyltransferase domain Sulfotransfer_1 PF00685.27 CBY41173.1 - 0.0098 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 CBY41173.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain EGF_CA PF07645.15 CBY41174.1 - 6.6e-18 64.6 58.8 1.2e-09 38.2 10.3 4.1 4 0 0 4 4 4 3 Calcium-binding EGF domain cEGF PF12662.7 CBY41174.1 - 1.9e-12 46.8 18.1 2.4e-05 24.1 2.5 3.9 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY41174.1 - 7.6e-12 45.2 57.5 4.6e-06 26.7 10.1 5.0 5 0 0 5 5 5 3 EGF domain EGF PF00008.27 CBY41174.1 - 7.1e-11 42.2 37.8 6e-06 26.5 7.1 3.9 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.7 CBY41174.1 - 2.2e-07 31.3 27.9 0.0024 18.4 3.7 4.0 3 0 0 3 3 3 3 Human growth factor-like EGF FXa_inhibition PF14670.6 CBY41174.1 - 7.1e-05 23.0 35.9 0.032 14.5 5.9 4.5 3 2 1 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY41174.1 - 0.00035 20.6 40.9 0.21 11.7 6.6 3.7 3 0 0 3 3 3 3 MSP1 EGF domain 1 TFIIA PF03153.13 CBY41174.1 - 0.22 11.5 10.5 0.44 10.5 10.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIP PF00230.20 CBY41176.1 - 3.6e-39 134.8 11.0 4.7e-39 134.4 11.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sulfate_transp PF00916.20 CBY41176.1 - 0.001 17.9 1.6 0.001 17.9 1.6 1.6 2 0 0 2 2 2 1 Sulfate permease family DUF5637 PF18687.1 CBY41176.1 - 0.054 13.5 1.8 0.15 12.1 1.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5637) DUF2093 PF09866.9 CBY41176.1 - 0.45 10.0 4.3 7.1 6.2 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) B12D PF06522.11 CBY41176.1 - 0.59 10.0 1.8 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Transglut_C PF00927.22 CBY41178.1 - 2.2e-17 63.1 0.0 6.3e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Transglut_core PF01841.19 CBY41178.1 - 6.7e-16 58.7 0.4 1.3e-15 57.9 0.4 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Alpha_adaptinC2 PF02883.20 CBY41178.1 - 0.17 12.2 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Adaptin C-terminal domain TRM PF02005.16 CBY41179.1 - 7.4e-111 370.9 0.0 9.6e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 CBY41179.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ribosomal_L27A PF00828.19 CBY41181.1 - 3.5e-24 85.9 0.0 5.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RIBIOP_C PF04950.12 CBY41183.1 - 2.1e-12 47.1 0.0 2.1e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBY41183.1 - 1.2e-05 25.3 0.1 0.00012 22.0 0.1 2.5 1 1 0 1 1 1 1 AARP2CN (NUC121) domain Pes-10 PF07149.11 CBY41183.1 - 0.61 9.1 12.4 0.92 8.5 12.4 1.2 1 0 0 1 1 1 0 Pes-10 TCTP PF00838.17 CBY41184.1 - 1.5e-59 201.0 0.0 1.7e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ndc1_Nup PF09531.10 CBY41185.1 - 1.1e-06 27.7 0.0 1.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup CRCB PF02537.15 CBY41186.1 - 1.7e-31 108.4 15.9 7.1e-17 61.5 2.2 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Gpi1 PF05024.15 CBY41186.1 - 0.081 13.0 7.0 0.036 14.2 3.9 2.0 2 0 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) SUR7 PF06687.12 CBY41186.1 - 0.19 11.3 7.3 0.27 10.9 0.6 2.8 2 1 1 3 3 3 0 SUR7/PalI family DUF4477 PF14780.6 CBY41187.1 - 0.0005 19.8 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Ribosomal_L21e PF01157.18 CBY41188.1 - 8.4e-45 150.8 6.1 8.4e-45 150.8 6.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e PDZ PF00595.24 CBY41189.1 - 1.8e-07 31.4 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY41189.1 - 0.0002 21.6 0.1 0.00033 20.9 0.0 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY41189.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain DUF3394 PF11874.8 CBY41189.1 - 0.058 13.1 0.1 0.067 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Pep_M12B_propep PF01562.19 CBY41189.1 - 0.12 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Reprolysin family propeptide Piwi PF02171.17 CBY41190.1 - 5.5e-51 173.6 0.2 6.9e-51 173.3 0.2 1.1 1 0 0 1 1 1 1 Piwi domain DUF2046 PF09755.9 CBY41191.1 - 1.8e-135 451.0 54.0 2.3e-135 450.7 54.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) ASD2 PF08687.11 CBY41191.1 - 0.0028 17.3 15.6 0.0028 17.3 15.6 3.4 1 1 2 3 3 3 1 Apx/Shroom domain ASD2 WD40_alt PF14077.6 CBY41191.1 - 0.025 14.4 3.1 1.6 8.7 0.1 3.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF5082 PF16888.5 CBY41191.1 - 0.42 10.9 37.7 1.6 9.0 11.4 4.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) ATG16 PF08614.11 CBY41191.1 - 6.6 6.9 57.1 2.6 8.2 17.8 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CBY41191.1 - 8.8 6.3 65.5 13 5.8 14.2 4.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 CBY41192.1 - 4.3e-62 209.9 0.0 3.6e-38 131.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41192.1 - 5.9e-40 137.2 0.0 3.9e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBY41192.1 - 1.7e-05 24.3 0.0 0.0062 15.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBY41192.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM91_C PF14648.6 CBY41192.1 - 0.0036 16.2 0.0 0.0048 15.8 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus Pkinase_fungal PF17667.1 CBY41192.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBY41192.1 - 0.026 14.4 0.0 0.098 12.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Bax1-I PF01027.20 CBY41193.1 - 0.00014 21.8 6.1 0.00016 21.5 6.1 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SLATT_5 PF18160.1 CBY41193.1 - 0.26 10.6 3.5 0.42 9.9 3.5 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4231 PF14015.6 CBY41193.1 - 0.38 11.3 4.4 0.54 10.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Bax1-I PF01027.20 CBY41194.1 - 5e-12 46.1 4.3 5.4e-12 46.0 4.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 CBY41195.1 - 3.3e-52 173.3 22.7 3.2e-08 34.1 0.0 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY41195.1 - 7.9e-19 67.8 0.9 0.00025 21.3 0.2 6.1 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBY41195.1 - 4.6e-08 33.5 0.1 8.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 CBY41195.1 - 0.00016 21.1 0.0 2.6 7.3 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CBY41195.1 - 0.00017 20.6 0.0 0.81 8.6 0.0 3.6 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBY41195.1 - 0.00034 20.6 0.0 1.1 9.1 0.0 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBY41195.1 - 0.0073 16.2 0.7 24 5.0 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat ASH PF15780.5 CBY41195.1 - 0.018 15.2 0.0 6.2 7.1 0.0 3.0 2 1 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin IKI3 PF04762.12 CBY41195.1 - 0.13 10.3 0.0 0.33 8.9 0.0 1.7 2 0 0 2 2 2 0 IKI3 family AAA PF00004.29 CBY41196.1 - 7.5e-16 58.8 0.1 2e-15 57.4 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBY41196.1 - 3.3e-05 23.6 0.0 5.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 CBY41196.1 - 0.00017 21.9 0.0 0.00053 20.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 CBY41196.1 - 0.0011 18.9 0.1 0.0079 16.1 0.1 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBY41196.1 - 0.0013 18.6 0.7 0.043 13.6 0.7 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.6 CBY41196.1 - 0.0022 18.3 0.1 0.36 11.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CBY41196.1 - 0.0028 16.9 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CBY41196.1 - 0.0031 17.9 0.0 0.031 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain OSCP PF00213.18 CBY41196.1 - 0.0041 17.3 0.0 0.033 14.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit AAA_5 PF07728.14 CBY41196.1 - 0.013 15.4 0.0 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CBY41196.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 CBY41196.1 - 0.018 14.3 0.0 0.042 13.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 CBY41196.1 - 0.061 13.2 0.0 3.9 7.4 0.0 2.4 1 1 1 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 CBY41196.1 - 0.074 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 CBY41196.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin QRPTase_C PF01729.19 CBY41196.1 - 0.15 11.8 0.0 15 5.3 0.0 2.2 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain TsaE PF02367.17 CBY41196.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_S15 PF00312.22 CBY41197.1 - 0.018 15.2 0.5 0.018 15.2 0.5 2.6 3 0 0 3 3 3 0 Ribosomal protein S15 zf-C4H2 PF10146.9 CBY41197.1 - 2.7 8.3 5.9 5.5 7.2 5.9 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein adh_short PF00106.25 CBY41199.1 - 1.6e-22 79.9 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY41199.1 - 5.6e-16 58.8 0.0 9.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY41199.1 - 2.3e-06 27.7 0.0 8.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 CBY41199.1 - 0.017 15.1 0.2 0.091 12.7 0.2 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF3311 PF11755.8 CBY41199.1 - 0.038 13.9 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Epimerase PF01370.21 CBY41199.1 - 0.039 13.4 0.1 0.86 9.0 0.0 2.4 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 CBY41199.1 - 0.063 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family p450 PF00067.22 CBY41201.1 - 1e-71 242.1 0.2 1.3e-71 241.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHGN PF05679.16 CBY41202.1 - 1.8e-72 244.8 1.9 9.5e-60 202.9 0.1 2.1 1 1 0 2 2 2 2 Chondroitin N-acetylgalactosaminyltransferase Fringe PF02434.16 CBY41202.1 - 8.7e-13 48.3 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Glyco_transf_7C PF02709.14 CBY41202.1 - 1.8e-09 37.1 0.1 4.3e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Galactosyl_T PF01762.21 CBY41202.1 - 7.9e-05 22.5 0.0 0.13 12.0 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase Glyco_tranf_2_2 PF10111.9 CBY41202.1 - 0.0028 17.2 0.5 0.007 15.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2024 PF09630.10 CBY41202.1 - 0.29 11.0 3.9 0.49 10.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) 5_nucleotid PF05761.14 CBY41203.1 - 2e-28 99.5 0.1 2.7e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 5' nucleotidase family Nnf1 PF03980.14 CBY41203.1 - 0.082 13.3 0.8 0.79 10.1 0.1 2.2 2 0 0 2 2 2 0 Nnf1 Sulfatase PF00884.23 CBY41206.1 - 4.9e-59 200.2 0.1 5.8e-59 200.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY41206.1 - 5.8e-05 22.8 0.6 0.016 14.8 0.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RT_RNaseH_2 PF17919.1 CBY41207.1 - 2.2e-25 88.6 0.0 4.3e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY41207.1 - 7e-19 68.1 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY41207.1 - 2e-16 60.2 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY41207.1 - 2.1e-14 53.7 0.0 1.3e-13 51.2 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY41207.1 - 7e-08 32.5 0.2 1.8e-07 31.1 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CBY41207.1 - 0.0016 18.6 0.3 0.0048 17.1 0.3 1.8 1 0 0 1 1 1 1 H2C2 zinc finger MRP-S32 PF10210.9 CBY41208.1 - 0.0011 19.5 0.7 0.0013 19.2 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S32 Med19 PF10278.9 CBY41208.1 - 0.057 13.3 0.6 0.066 13.2 0.6 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4407 PF14362.6 CBY41209.1 - 0.026 13.9 31.5 0.26 10.6 9.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ANAPC16 PF17256.2 CBY41209.1 - 0.077 13.4 0.2 0.077 13.4 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, subunit 16 DUF948 PF06103.11 CBY41209.1 - 0.2 11.9 3.9 0.3 11.4 0.1 3.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 CBY41209.1 - 0.37 10.8 3.8 0.46 10.5 0.2 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 CBY41209.1 - 0.54 10.8 56.1 0.16 12.5 13.0 4.2 1 1 3 4 4 4 0 Apg6 coiled-coil region EzrA PF06160.12 CBY41209.1 - 0.64 8.1 42.9 12 3.9 42.9 2.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA RRF_GI PF12614.8 CBY41210.1 - 0.012 15.7 5.4 0.014 15.5 4.6 1.5 1 1 0 1 1 1 0 Ribosome recycling factor ATPgrasp_Ter PF15632.6 CBY41210.1 - 0.034 13.9 1.5 0.053 13.3 1.5 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Exonuc_VII_L PF02601.15 CBY41210.1 - 0.058 13.0 14.1 0.068 12.7 14.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2730 PF10805.8 CBY41210.1 - 0.26 11.4 10.4 0.049 13.7 3.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF87 PF01935.17 CBY41210.1 - 0.48 10.5 8.4 0.6 10.2 8.4 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain Tropomyosin PF00261.20 CBY41210.1 - 0.7 9.2 28.6 2.2 7.6 1.0 2.6 1 1 0 2 2 2 0 Tropomyosin FlxA PF14282.6 CBY41210.1 - 1.2 9.2 16.7 2.3 8.3 11.3 2.5 1 1 1 2 2 2 0 FlxA-like protein Atg14 PF10186.9 CBY41210.1 - 2.7 7.0 20.3 3.2 6.8 20.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CBY41210.1 - 6.8 4.5 13.5 7.2 4.4 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans_2 PF07885.16 CBY41211.1 - 6e-19 67.8 15.2 6.5e-15 54.9 10.3 2.3 2 0 0 2 2 2 2 Ion channel EI24 PF07264.11 CBY41211.1 - 0.0043 17.3 7.4 0.005 17.1 2.7 2.1 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Ion_trans PF00520.31 CBY41211.1 - 0.022 14.0 15.4 0.12 11.6 12.3 2.2 2 0 0 2 2 2 0 Ion transport protein fn3 PF00041.21 CBY41212.1 - 8e-49 163.9 11.5 7.2e-15 55.1 0.0 6.4 6 0 0 6 6 6 5 Fibronectin type III domain I-set PF07679.16 CBY41212.1 - 6.3e-29 99.9 2.3 1.2e-13 50.9 0.0 4.8 5 0 0 5 5 5 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY41212.1 - 3.3e-22 78.9 3.3 5.8e-12 46.0 0.1 4.7 4 0 0 4 4 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY41212.1 - 9.4e-15 54.7 0.4 3.4e-07 30.5 0.0 3.7 3 0 0 3 3 3 3 Immunoglobulin domain Bravo_FIGEY PF13882.6 CBY41212.1 - 3.8e-13 50.6 1.7 1.5e-12 48.7 1.7 2.2 1 0 0 1 1 1 1 Bravo-like intracellular region ig PF00047.25 CBY41212.1 - 9e-13 48.2 0.1 5.7e-07 29.6 0.0 3.9 3 0 0 3 3 3 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY41212.1 - 6e-10 39.6 6.4 0.027 15.0 0.1 5.2 5 1 0 5 5 5 3 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBY41212.1 - 1.2e-05 25.5 0.9 2.8 8.3 0.0 5.3 6 0 0 6 6 5 1 Interferon-alpha/beta receptor, fibronectin type III C2-set_2 PF08205.12 CBY41212.1 - 2.3e-05 24.4 0.2 0.00045 20.2 0.1 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain V-set PF07686.17 CBY41212.1 - 0.00048 20.3 3.3 0.87 9.8 0.0 4.9 3 2 1 5 5 5 1 Immunoglobulin V-set domain Y_Y_Y PF07495.13 CBY41212.1 - 0.0028 17.6 1.2 8.8 6.4 0.0 5.0 5 0 0 5 5 5 1 Y_Y_Y domain Receptor_2B4 PF11465.8 CBY41212.1 - 0.043 14.0 1.8 3 8.1 0.0 3.8 4 0 0 4 4 4 0 Natural killer cell receptor 2B4 Glyco_transf_10 PF00852.19 CBY41214.1 - 1.5e-22 80.2 3.9 3.2e-14 53.0 2.3 2.5 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 CBY41214.1 - 5.9e-13 49.2 0.3 2.4e-12 47.3 0.3 2.1 1 1 0 1 1 1 1 Fucosyltransferase, N-terminal DUF1027 PF06265.11 CBY41215.1 - 0.12 12.4 2.4 0.37 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1027) Pterin_4a PF01329.19 CBY41215.1 - 0.15 12.2 0.3 0.45 10.7 0.1 1.9 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase eIF2A PF08662.11 CBY41216.1 - 0.1 12.5 0.6 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A LSM PF01423.22 CBY41217.1 - 3.9e-17 61.7 0.5 4.3e-17 61.6 0.5 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBY41217.1 - 0.09 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain UbiA PF01040.18 CBY41218.1 - 3.1e-28 98.8 12.5 6.1e-27 94.5 9.4 3.4 1 1 1 2 2 2 1 UbiA prenyltransferase family VirB3 PF05101.13 CBY41218.1 - 0.3 11.3 2.4 6 7.2 0.2 2.9 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Ribosomal_S10 PF00338.22 CBY41219.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.9 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e TSP_1 PF00090.19 CBY41221.1 - 1.8e-40 136.9 178.1 2.8e-08 33.8 15.0 15.1 16 0 0 16 16 16 9 Thrombospondin type 1 domain Lipocalin_9 PF17186.4 CBY41221.1 - 0.13 12.5 1.2 0.27 11.5 1.2 1.4 1 0 0 1 1 1 0 Lipocalin-like domain TSP_1 PF00090.19 CBY41222.1 - 1.4e-31 108.4 56.8 1e-09 38.5 11.5 4.5 4 0 0 4 4 4 4 Thrombospondin type 1 domain Thyroglobulin_1 PF00086.18 CBY41223.1 - 1.4e-11 43.9 5.1 1.4e-11 43.9 5.1 1.5 2 0 0 2 2 2 1 Thyroglobulin type-1 repeat SNF5 PF04855.12 CBY41225.1 - 3.4e-54 184.1 0.0 3.1e-50 171.2 0.0 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 40S_S4_C PF16121.5 CBY41227.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus TSP_1 PF00090.19 CBY41229.1 - 1.7e-21 76.2 133.3 2e-07 31.1 9.3 10.3 9 1 1 10 10 10 6 Thrombospondin type 1 domain ShK PF01549.24 CBY41229.1 - 5.3e-16 58.9 152.7 3.3e-07 30.7 5.5 12.3 11 1 0 11 11 11 8 ShK domain-like ShK PF01549.24 CBY41230.1 - 1.4e-30 105.5 118.8 3.1e-08 34.0 8.6 9.4 9 0 0 9 9 9 8 ShK domain-like DnaJ PF00226.31 CBY41231.1 - 8.9e-08 32.2 0.3 0.007 16.5 0.0 2.7 2 1 1 3 3 3 2 DnaJ domain F-box-like PF12937.7 CBY41231.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBY41231.1 - 0.0034 17.2 0.1 0.047 13.6 0.1 2.2 1 1 0 1 1 1 1 F-box domain RPT PF13446.6 CBY41231.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Cyclin_N PF00134.23 CBY41232.1 - 2.3e-29 101.7 0.0 4.6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4200 PF13863.6 CBY41232.1 - 1.6 9.2 7.1 0.74 10.2 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) adh_short PF00106.25 CBY41233.1 - 1.1e-41 142.5 3.3 2.7e-41 141.2 3.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY41233.1 - 2.6e-33 115.6 0.2 4.4e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY41233.1 - 2.3e-11 43.9 0.4 4.5e-11 43.0 0.4 1.5 1 0 0 1 1 1 1 KR domain DUF4313 PF14190.6 CBY41233.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Lipase PF00151.19 CBY41234.1 - 1.5e-29 103.4 0.0 2e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 CBY41234.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 CBY41234.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ADK PF00406.22 CBY41237.1 - 4.9e-39 133.8 0.0 5.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBY41237.1 - 7.2e-35 120.4 0.0 8.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBY41237.1 - 1.1e-09 38.9 0.1 2e-09 38.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBY41237.1 - 5.6e-07 29.8 0.1 2.6e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CBY41237.1 - 0.00055 19.7 0.1 0.74 9.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 CBY41237.1 - 0.00062 19.7 0.1 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CBY41237.1 - 0.00077 18.8 0.0 0.0028 17.0 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase1 PF18748.1 CBY41237.1 - 0.01 15.3 0.0 0.051 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 zf-C3HC4_2 PF13923.6 CBY41238.1 - 4.3e-08 32.9 8.6 4.3e-08 32.9 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY41238.1 - 3.8e-07 30.3 8.9 4.9e-07 30.0 7.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBY41238.1 - 2.7e-06 27.6 5.9 6.8e-06 26.3 5.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY41238.1 - 7.5e-05 22.7 4.2 0.00016 21.7 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CBY41238.1 - 0.00053 19.9 7.8 0.0012 18.8 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY41238.1 - 0.0012 18.6 6.8 0.003 17.4 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY41238.1 - 0.0015 18.4 4.5 0.0031 17.4 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CBY41238.1 - 0.0021 18.0 10.4 0.0043 17.1 10.4 1.5 1 0 0 1 1 1 1 Zinc-finger zf-Nse PF11789.8 CBY41238.1 - 0.033 14.0 3.0 0.11 12.3 3.0 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CBY41238.1 - 0.057 13.4 8.6 0.12 12.5 4.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 CBY41238.1 - 0.15 12.4 7.1 0.4 11.0 7.1 1.8 1 0 0 1 1 1 0 RING-like domain FYVE_2 PF02318.16 CBY41238.1 - 1.3 9.3 10.1 0.28 11.4 5.9 2.1 2 1 0 2 2 2 0 FYVE-type zinc finger KH_1 PF00013.29 CBY41240.1 - 1.6e-06 27.8 0.5 1.3e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 CBY41240.1 - 7.5e-05 22.5 0.5 0.0001 22.0 0.5 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CBY41240.1 - 0.0002 21.2 0.3 0.0003 20.6 0.3 1.4 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 CBY41240.1 - 0.066 13.3 0.5 0.27 11.3 0.1 2.0 2 1 0 2 2 2 0 NusA-like KH domain WD40 PF00400.32 CBY41241.1 - 1e-26 92.7 18.6 1e-06 29.4 0.1 10.0 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY41241.1 - 4.5e-20 71.7 0.1 0.0049 17.1 0.0 8.2 5 1 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBY41241.1 - 7.4e-08 32.7 0.1 1.2e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CBY41241.1 - 0.0015 17.5 0.7 1.5 7.7 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC45 PF02724.14 CBY41241.1 - 0.11 10.8 0.9 0.16 10.2 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tetraspanin PF00335.20 CBY41242.1 - 7.9e-22 78.1 2.2 9.4e-22 77.8 2.2 1.1 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.23 CBY41242.1 - 5.2e-05 23.3 3.4 5.2e-05 23.3 3.4 1.5 2 0 0 2 2 2 1 Membrane-associating domain DUF423 PF04241.15 CBY41242.1 - 1 9.6 9.8 1.2 9.4 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF4579 PF15158.6 CBY41242.1 - 2.3 7.9 8.0 2.9 7.6 2.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4579) Herpes_LMP1 PF05297.11 CBY41242.1 - 2.6 7.2 9.0 4.4 6.4 9.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Brix PF04427.18 CBY41243.1 - 2.1e-20 73.6 0.1 2.5e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Glyco_transf_64 PF09258.10 CBY41244.1 - 6.2e-77 258.2 0.0 7.5e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain UQ_con PF00179.26 CBY41245.1 - 5.2e-15 55.3 0.0 8.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CDI PF02234.19 CBY41246.1 - 8e-12 45.2 2.1 1.8e-11 44.1 2.1 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor WAPL PF07814.13 CBY41246.1 - 0.045 12.5 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin zf-C2H2 PF00096.26 CBY41247.1 - 3e-13 49.4 21.8 1.2e-05 25.4 1.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY41247.1 - 3.4e-10 39.9 22.1 6.2e-07 29.6 1.7 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY41247.1 - 7.5e-09 35.7 17.9 0.0034 18.1 1.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CBY41247.1 - 0.0008 19.1 13.7 0.001 18.8 1.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CBY41247.1 - 0.00091 19.2 13.2 0.066 13.2 1.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CBY41247.1 - 0.017 15.4 0.8 0.017 15.4 0.8 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY41247.1 - 0.028 14.8 0.4 0.028 14.8 0.4 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 CBY41247.1 - 0.45 10.7 3.9 0.59 10.3 0.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain RHINO PF15319.6 CBY41247.1 - 1.4 8.9 8.6 0.079 13.0 1.9 2.1 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein zf-C2HC_2 PF13913.6 CBY41247.1 - 1.9 8.4 7.2 0.27 11.2 2.2 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 CBY41247.1 - 3.2 8.2 12.1 30 5.0 2.1 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) T-box PF00907.22 CBY41248.1 - 2.9e-31 109.2 1.7 3.2e-31 109.0 1.7 1.0 1 0 0 1 1 1 1 T-box GST_N PF02798.20 CBY41249.1 - 2.3e-08 34.2 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBY41249.1 - 0.007 16.8 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBY41249.1 - 0.0097 16.1 0.0 0.021 15.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CBY41249.1 - 0.034 14.5 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein AMP-binding PF00501.28 CBY41250.1 - 5.1e-49 167.0 0.0 6.1e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Nebulin PF00880.18 CBY41251.1 - 2.3e-48 161.5 69.8 2.7e-08 33.5 0.1 16.5 19 0 0 19 19 19 12 Nebulin repeat SH3_9 PF14604.6 CBY41251.1 - 1e-11 44.5 0.1 1.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY41251.1 - 1.4e-10 40.6 0.0 3.8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY41251.1 - 0.00012 21.6 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ATP-gua_PtransN PF02807.15 CBY41252.1 - 1.3e-21 76.7 0.0 2.1e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ATP-gua_Ptrans PF00217.19 CBY41252.1 - 3.7e-21 75.6 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain NUFIP1 PF10453.9 CBY41253.1 - 0.16 11.8 0.1 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Zona_pellucida PF00100.23 CBY41254.1 - 2.4e-24 86.5 6.0 2.8e-24 86.3 6.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Dehydrin PF00257.19 CBY41255.1 - 0.00084 19.9 0.6 0.0014 19.2 0.6 1.3 1 0 0 1 1 1 1 Dehydrin FG-GAP PF01839.23 CBY41255.1 - 0.077 13.1 0.9 0.077 13.1 0.9 2.7 2 0 0 2 2 2 0 FG-GAP repeat CbtB PF09489.10 CBY41255.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) TPPII_N PF12583.8 CBY41255.1 - 3.9 8.0 9.7 0.51 10.9 5.7 1.5 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DUF3754 PF12576.8 CBY41256.1 - 0.0017 18.3 0.2 0.0025 17.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) PhoH PF02562.16 CBY41257.1 - 9.7e-05 21.9 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 CBY41257.1 - 0.027 14.5 0.0 0.031 14.3 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CBY41257.1 - 0.082 12.7 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 CBY41258.1 - 1.4e-12 47.6 0.1 1.7e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 DEAD_2 GATA PF00320.27 CBY41259.1 - 1.1e-16 60.1 5.7 1.9e-16 59.4 5.7 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CBY41259.1 - 0.0064 16.0 1.7 0.0094 15.5 1.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding Vps36-NZF-N PF16988.5 CBY41259.1 - 0.061 12.7 0.5 0.17 11.3 0.6 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ion_trans_2 PF07885.16 CBY41260.1 - 0.0018 18.2 5.3 0.0041 17.1 4.9 1.8 1 1 0 1 1 1 1 Ion channel Popeye PF04831.13 CBY41260.1 - 0.22 11.7 6.9 0.18 12.0 2.6 2.0 1 1 1 2 2 2 0 Popeye protein conserved region dNK PF01712.19 CBY41264.1 - 1.8e-19 70.4 3.2 1e-18 68.0 3.2 1.9 1 1 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 CBY41264.1 - 6.3e-06 26.0 0.5 2.7e-05 24.0 0.1 2.1 2 1 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 CBY41264.1 - 0.098 13.1 0.0 3 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 CBY41265.1 - 4.8e-25 87.9 4.5 1.7e-10 41.4 0.0 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBY41265.1 - 1.9e-23 82.2 12.7 6.1e-09 36.0 0.0 5.8 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY41265.1 - 4.6e-23 81.3 5.1 1.1e-06 29.1 0.2 5.7 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY41265.1 - 1.8e-21 75.6 11.2 1.4e-05 25.3 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CBY41265.1 - 3.1e-16 57.8 7.2 0.0002 21.5 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF2730 PF10805.8 CBY41265.1 - 0.039 14.0 0.2 0.098 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) GAIN_A PF18619.1 CBY41265.1 - 0.049 13.8 0.2 0.14 12.4 0.2 1.9 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Tape_meas_lam_C PF09718.10 CBY41265.1 - 0.088 13.0 0.2 0.25 11.5 0.2 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF5344 PF17279.2 CBY41265.1 - 0.14 12.7 3.8 0.3 11.7 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5344) FAM176 PF14851.6 CBY41265.1 - 1.6 8.4 7.1 0.14 11.8 2.2 1.7 2 0 0 2 2 2 0 FAM176 family RRS1 PF04939.12 CBY41266.1 - 7.9e-40 136.4 11.7 7.9e-40 136.4 11.7 2.3 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) YscJ_FliF PF01514.17 CBY41266.1 - 0.12 12.1 4.7 2.9 7.5 0.2 2.7 3 0 0 3 3 3 0 Secretory protein of YscJ/FliF family Trypsin PF00089.26 CBY41267.1 - 1.5e-41 142.6 0.5 2.2e-41 142.1 0.5 1.2 1 0 0 1 1 1 1 Trypsin EGF PF00008.27 CBY41267.1 - 2.7e-05 24.4 8.2 2.7e-05 24.4 8.2 4.4 4 0 0 4 4 4 3 EGF-like domain Trypsin_2 PF13365.6 CBY41267.1 - 0.00021 22.2 0.0 0.00048 21.0 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain hEGF PF12661.7 CBY41267.1 - 0.0032 18.1 7.2 0.0032 18.1 7.2 6.0 5 1 0 5 5 5 1 Human growth factor-like EGF DUF1986 PF09342.11 CBY41267.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) EGF_CA PF07645.15 CBY41268.1 - 9e-62 205.0 125.0 2.2e-11 43.8 4.8 10.1 10 0 0 10 10 10 8 Calcium-binding EGF domain cEGF PF12662.7 CBY41268.1 - 3.3e-34 116.4 73.5 4.2e-07 29.8 0.6 11.0 9 3 0 9 9 9 7 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY41268.1 - 4.6e-11 42.7 109.6 4.2e-06 26.9 5.4 10.4 10 1 1 11 11 11 7 EGF domain FXa_inhibition PF14670.6 CBY41268.1 - 1e-07 32.1 113.6 2.6e-05 24.4 11.2 10.0 8 1 0 9 9 9 7 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.7 CBY41268.1 - 1.5e-05 25.0 2.7 1.5e-05 25.0 2.7 10.1 10 1 0 10 10 10 2 MSP1 EGF domain 1 hEGF PF12661.7 CBY41268.1 - 0.00036 21.1 3.6 0.00036 21.1 3.6 13.3 13 2 0 13 13 13 4 Human growth factor-like EGF Zip PF02535.22 CBY41269.1 - 8.4e-51 173.2 19.7 8.5e-48 163.3 19.7 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter Laminin_EGF PF00053.24 CBY41269.1 - 1.7 8.9 13.6 2.7 8.2 12.6 1.9 1 1 0 1 1 1 0 Laminin EGF domain DUF202 PF02656.15 CBY41270.1 - 0.16 12.5 2.4 7.8 7.0 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Amnionless PF14828.6 CBY41272.1 - 2e-12 46.7 6.9 2.3e-12 46.5 6.9 1.0 1 0 0 1 1 1 1 Amnionless zf-C4 PF00105.18 CBY41273.1 - 1.5e-31 108.6 16.2 2.2e-31 108.1 16.2 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) DnaI_N PF07319.11 CBY41274.1 - 0.027 15.1 0.5 0.3 11.8 0.1 3.0 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus DUF3398 PF11878.8 CBY41274.1 - 0.061 13.8 0.4 2.1 8.8 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Neur_chan_memb PF02932.16 CBY41276.1 - 2.4e-49 168.6 10.4 1.6e-47 162.5 10.4 2.2 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 CBY41276.1 - 3.7e-45 154.0 0.0 5.2e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain GST_C_3 PF14497.6 CBY41276.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBY41276.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ion_trans PF00520.31 CBY41278.1 - 3e-14 52.9 2.3 4.7e-14 52.2 2.3 1.3 1 0 0 1 1 1 1 Ion transport protein RVT_1 PF00078.27 CBY41278.1 - 0.032 13.7 0.1 0.053 13.0 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) EF1_GNE PF00736.19 CBY41279.1 - 5.4e-33 113.0 1.4 5.4e-33 113.0 1.4 1.5 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY41279.1 - 3.4e-14 53.0 5.8 3.4e-14 53.0 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 CBY41279.1 - 0.0055 16.5 3.0 0.007 16.1 3.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Dpy-30 PF05186.13 CBY41280.1 - 1.1e-15 57.0 0.9 2.6e-11 43.0 0.1 2.6 2 1 0 2 2 2 2 Dpy-30 motif ANAPC3 PF12895.7 CBY41280.1 - 0.0094 16.2 0.3 2.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PDCD9 PF07147.12 CBY41282.1 - 2.4e-05 23.7 0.1 2.8e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF4392 PF14336.6 CBY41285.1 - 9.7e-66 222.2 0.0 1.7e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF1445 PF07286.12 CBY41285.1 - 8.6e-55 184.6 0.0 3e-54 182.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) zf-H2C2_2 PF13465.6 CBY41287.1 - 2.3e-20 72.0 14.6 6.7e-08 32.6 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY41287.1 - 1.9e-19 68.9 16.1 6.4e-07 29.5 3.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY41287.1 - 9.6e-15 54.0 12.4 0.0002 21.9 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBY41287.1 - 4.3e-12 46.1 2.5 3e-08 33.8 1.1 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBY41287.1 - 1.6e-10 40.9 1.1 0.0017 18.6 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBY41287.1 - 6.8e-09 35.5 6.5 0.0097 15.9 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.15 CBY41287.1 - 5.9e-08 32.6 10.1 0.015 15.3 0.7 3.9 2 1 1 3 3 3 3 BED zinc finger GAGA PF09237.11 CBY41287.1 - 4.4e-07 29.6 7.8 0.0068 16.2 0.4 3.6 1 1 2 3 3 3 2 GAGA factor zf-met PF12874.7 CBY41287.1 - 5.3e-05 23.5 5.5 1.3 9.5 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CBY41287.1 - 0.00032 20.4 24.3 0.0097 15.6 0.3 4.6 4 1 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CBY41287.1 - 0.00032 20.4 11.5 0.086 12.6 0.2 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBY41287.1 - 0.0037 17.6 2.7 3.7 7.9 0.1 3.4 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CBY41287.1 - 0.0065 16.1 0.7 17 5.1 0.0 3.2 1 1 2 3 3 3 0 MYST family zinc finger domain zf_UBZ PF18439.1 CBY41287.1 - 0.0081 15.7 2.4 1.5 8.5 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger DUF4611 PF15387.6 CBY41287.1 - 0.029 14.6 0.7 0.057 13.6 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zinc_ribbon_15 PF17032.5 CBY41287.1 - 0.04 14.7 1.4 2.2 9.1 0.3 2.5 1 1 1 2 2 2 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 CBY41287.1 - 0.056 13.5 7.1 6.1 7.0 0.4 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C2H2_8 PF15909.5 CBY41287.1 - 0.073 13.4 4.7 1.2 9.5 1.7 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 CBY41287.1 - 0.14 12.1 13.4 3.8 7.5 1.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF629 PF04780.12 CBY41287.1 - 0.18 10.3 1.7 3.3 6.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF629) UBZ_FAAP20 PF15750.5 CBY41287.1 - 0.23 11.4 2.8 18 5.4 0.0 2.9 3 0 0 3 3 2 0 Ubiquitin-binding zinc-finger Elf1 PF05129.13 CBY41287.1 - 0.28 11.3 4.1 12 6.1 0.1 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_9 PF16293.5 CBY41287.1 - 0.34 10.8 1.8 45 4.0 0.1 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF1644 PF07800.12 CBY41287.1 - 0.34 10.9 10.5 6.8 6.7 8.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-AN1 PF01428.16 CBY41287.1 - 0.38 11.0 12.3 1.1 9.4 0.5 3.6 4 0 0 4 4 3 0 AN1-like Zinc finger zf-C2H2_3rep PF18868.1 CBY41287.1 - 0.5 11.0 13.3 1.2 9.8 0.7 3.8 2 1 2 4 4 3 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 CBY41287.1 - 0.65 10.5 6.6 4.7 7.7 0.5 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Sugar_tr PF00083.24 CBY41288.1 - 9.5e-25 87.4 24.1 2.9e-24 85.7 24.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY41288.1 - 5e-23 81.6 55.7 3e-17 62.6 27.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 CBY41289.1 - 1.4e-104 349.7 0.2 1.4e-104 349.7 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY41289.1 - 4.6e-28 98.0 0.0 2.1e-27 95.9 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding CorA PF01544.18 CBY41289.1 - 0.88 8.8 11.2 0.53 9.5 9.2 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CT_C_D PF02682.16 CBY41289.1 - 1.1 9.0 6.4 2.7 7.7 2.6 2.4 2 1 1 3 3 3 0 Carboxyltransferase domain, subdomain C and D Cbl_N PF02262.16 CBY41289.1 - 1.3 9.0 6.3 2 8.4 2.4 2.8 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 ABC_tran PF00005.27 CBY41289.1 - 5.1 7.6 8.0 1.2 9.7 2.8 2.5 2 1 1 3 3 3 0 ABC transporter BAR_3_WASP_bdg PF10456.9 CBY41290.1 - 1e-20 74.2 0.2 1.4e-20 73.8 0.2 1.1 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Vps5 PF09325.10 CBY41290.1 - 1.6e-06 27.9 2.5 5e-06 26.2 1.0 2.1 1 1 1 2 2 2 1 Vps5 C terminal like FAM92 PF06730.11 CBY41290.1 - 0.0045 16.4 1.8 0.0057 16.1 0.5 1.7 2 0 0 2 2 2 1 FAM92 protein DUF1451 PF07295.11 CBY41290.1 - 0.025 14.6 0.5 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain E1-E2_ATPase PF00122.20 CBY41291.1 - 1.3e-33 116.0 0.1 1.3e-33 116.0 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBY41291.1 - 1.3e-17 64.8 0.2 4.5e-17 63.1 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY41291.1 - 2.8e-09 37.0 0.0 1.2e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY41291.1 - 4.9e-05 22.9 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ribosomal_L21p PF00829.21 CBY41291.1 - 0.0069 16.6 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Hydrolase_3 PF08282.12 CBY41291.1 - 0.04 13.7 1.2 6.8 6.3 0.1 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase OSTbeta PF15048.6 CBY41291.1 - 0.093 12.9 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Mrr_cat_2 PF13156.6 CBY41291.1 - 0.15 12.0 0.9 0.58 10.1 0.3 2.1 2 0 0 2 2 2 0 Restriction endonuclease Tetraspanin PF00335.20 CBY41292.1 - 6.1e-10 39.2 15.7 1.4e-08 34.8 15.7 2.2 1 1 0 1 1 1 1 Tetraspanin family Herpes_UL1 PF05259.11 CBY41292.1 - 0.062 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Cation_ATPase_C PF00689.21 CBY41292.1 - 0.51 10.0 6.4 0.086 12.5 2.4 1.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.9 CBY41292.1 - 3.5 6.3 8.5 1.6 7.4 5.1 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TraG_N PF07916.11 CBY41292.1 - 7.1 5.4 5.9 4.8 5.9 2.9 2.0 1 1 1 2 2 2 0 TraG-like protein, N-terminal region SNF PF00209.18 CBY41297.1 - 1.8e-158 528.5 38.5 2e-158 528.3 38.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family PK PF00224.21 CBY41298.1 - 5.4e-65 219.6 0.9 6.5e-65 219.3 0.9 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain IMPDH PF00478.25 CBY41298.1 - 0.00013 21.1 0.1 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_U32 PF01136.19 CBY41298.1 - 0.058 12.5 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 Radical_SAM PF04055.21 CBY41298.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily DUF4423 PF14394.6 CBY41298.1 - 0.15 11.8 0.0 0.51 10.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) eIF2A PF08662.11 CBY41299.1 - 2e-61 207.3 0.0 2.7e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A zf-HC5HC2H_2 PF13832.6 CBY41301.1 - 1.9e-15 57.0 15.3 3.5e-15 56.1 6.7 3.0 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 CBY41301.1 - 4.6e-13 48.5 3.6 4.6e-13 48.5 3.6 3.4 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H PF13771.6 CBY41301.1 - 1.1e-10 41.5 20.9 2.2e-10 40.6 5.6 3.5 2 2 0 3 3 3 2 PHD-like zinc-binding domain PHD PF00628.29 CBY41301.1 - 5.3e-09 35.8 27.9 7.5e-09 35.3 6.0 4.0 4 0 0 4 4 4 2 PHD-finger zf-PHD-like PF15446.6 CBY41301.1 - 0.0028 17.3 2.5 0.0028 17.3 2.5 3.2 2 2 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Nore1-SARAH PF16517.5 CBY41301.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain zf-UDP PF14569.6 CBY41301.1 - 0.0064 16.6 1.4 0.0064 16.6 1.4 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_1 PF14446.6 CBY41301.1 - 0.02 14.8 16.8 0.053 13.4 3.5 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CBY41301.1 - 6.6 7.1 23.6 0.24 11.7 1.8 3.7 3 1 0 3 3 3 0 C1 domain Phage_integrase PF00589.22 CBY41303.1 - 1.5e-09 37.9 0.0 6.3e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family DUF1359 PF07097.11 CBY41303.1 - 0.095 13.0 0.0 3.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) API5 PF05918.11 CBY41303.1 - 0.45 9.3 6.2 0.78 8.5 6.2 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) COesterase PF00135.28 CBY41304.1 - 1.1e-57 196.0 0.0 1.5e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY41304.1 - 2.7e-13 50.3 0.0 3.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY41304.1 - 0.0019 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CBY41304.1 - 0.011 14.7 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 CBY41304.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PilJ_C PF18223.1 CBY41304.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Pili PilJ C-terminal domain Abhydrolase_6 PF12697.7 CBY41304.1 - 0.18 12.4 0.8 0.47 11.0 0.9 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Galactosyl_T PF01762.21 CBY41306.1 - 5.1e-38 130.8 0.1 1.1e-37 129.8 0.0 1.5 2 0 0 2 2 2 1 Galactosyltransferase Inositol_P PF00459.25 CBY41307.1 - 5.2e-35 121.3 0.0 6.5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family LSDAT_euk PF18139.1 CBY41308.1 - 8e-35 120.5 0.0 9.4e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 CBY41308.1 - 9.2e-18 64.2 0.0 4.4e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote DUF5524 PF17662.1 CBY41309.1 - 0.012 15.0 0.8 0.014 14.8 0.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5524) Imm52 PF15579.6 CBY41310.1 - 0.17 11.8 0.2 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 52 BRCT PF00533.26 CBY41311.1 - 1.1e-08 35.3 6.0 5.9e-05 23.4 0.1 3.1 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY41311.1 - 4.2e-07 30.3 1.7 0.0011 19.3 0.1 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CBY41311.1 - 8.3e-07 28.8 0.0 8.3e-07 28.8 0.0 3.5 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain Peptidase_S49_N PF08496.10 CBY41311.1 - 0.013 15.6 3.0 0.013 15.6 3.0 3.9 5 0 0 5 5 5 0 Peptidase family S49 N-terminal LIG3_BRCT PF16759.5 CBY41311.1 - 0.022 15.0 6.1 0.033 14.5 0.2 3.4 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain CdhC PF03598.15 CBY41311.1 - 0.086 12.7 0.7 0.21 11.4 0.7 1.6 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Synaptobrevin PF00957.21 CBY41311.1 - 0.97 9.3 7.9 0.46 10.3 0.4 3.2 1 1 1 2 2 2 0 Synaptobrevin HMG_box_2 PF09011.10 CBY41316.1 - 6.3e-32 110.0 14.0 4e-16 59.4 2.3 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 CBY41316.1 - 2.9e-30 104.5 11.9 1.3e-17 64.0 3.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box MlaC PF05494.12 CBY41316.1 - 0.0056 16.4 1.2 0.094 12.5 0.2 2.1 2 0 0 2 2 2 1 MlaC protein HMG_box_5 PF14887.6 CBY41316.1 - 0.0077 16.2 2.7 0.0077 16.2 2.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 FTCD_C PF04961.12 CBY41316.1 - 2.1 8.1 8.4 3.9 7.2 0.3 2.1 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase eIF-5a PF01287.20 CBY41317.1 - 3.2e-22 78.4 3.8 4.1e-22 78.1 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PDEase_I PF00233.19 CBY41318.1 - 1.1e-30 107.2 4.7 1.6e-30 106.6 4.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 CBY41318.1 - 1.3e-06 28.2 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal ACC_central PF08326.12 CBY41320.1 - 0.0097 14.2 0.0 0.011 14.0 0.0 1.0 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DUF190 PF02641.15 CBY41320.1 - 0.022 15.0 0.1 5 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 DHODB_Fe-S_bind PF10418.9 CBY41322.1 - 0.016 15.0 6.7 0.95 9.3 0.2 4.0 4 0 0 4 4 4 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B TPR_1 PF00515.28 CBY41323.1 - 9.2e-14 50.6 0.1 3.2e-07 29.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBY41323.1 - 1.1e-10 40.8 0.3 7.7e-06 25.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41323.1 - 8.7e-08 31.8 2.3 3.7e-05 23.6 0.3 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41323.1 - 1.9e-05 24.9 0.1 0.0002 21.6 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY41323.1 - 4.9e-05 23.8 0.1 0.22 12.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY41323.1 - 0.00011 22.8 0.0 0.075 13.7 0.0 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CBY41323.1 - 0.00015 21.5 0.6 0.00094 19.0 0.1 2.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY41323.1 - 0.00048 20.0 0.4 0.0051 16.7 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY41323.1 - 0.001 19.7 0.1 0.17 12.7 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 CBY41323.1 - 0.015 15.8 0.4 0.26 11.8 0.0 3.3 3 1 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 CBY41323.1 - 0.032 14.6 0.0 5.5 7.5 0.0 3.3 2 1 2 4 4 4 0 HEAT repeats TPR_11 PF13414.6 CBY41323.1 - 0.046 13.4 0.5 17 5.2 0.1 3.2 2 1 1 3 3 3 0 TPR repeat TPR_17 PF13431.6 CBY41323.1 - 0.056 13.8 0.0 27 5.4 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBY41323.1 - 0.1 13.3 0.1 0.59 10.9 0.1 2.4 3 0 0 3 3 1 0 Tetratricopeptide repeat Arm PF00514.23 CBY41323.1 - 0.14 12.2 3.1 0.54 10.4 0.0 3.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TPR_9 PF13371.6 CBY41323.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 CBY41324.1 - 1.2e-29 102.3 0.0 1.2e-19 70.2 0.1 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY41324.1 - 1.5e-08 33.6 0.0 0.0013 18.1 0.1 2.6 2 0 0 2 2 2 2 EF hand APG6_N PF17675.1 CBY41324.1 - 5.4e-05 23.7 29.3 0.00099 19.6 8.3 2.7 2 1 2 4 4 4 2 Apg6 coiled-coil region EF-hand_6 PF13405.6 CBY41324.1 - 6.8e-05 22.5 0.0 0.93 9.6 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain CENP-F_leu_zip PF10473.9 CBY41324.1 - 0.00015 21.8 10.4 0.00015 21.8 10.4 2.4 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_7 PF13499.6 CBY41324.1 - 0.00037 20.9 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBY41324.1 - 0.0022 17.8 0.0 0.16 11.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair DUF3450 PF11932.8 CBY41324.1 - 0.0064 15.8 3.9 0.0064 15.8 3.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Spc24 PF08286.11 CBY41324.1 - 0.0084 16.3 9.7 0.21 11.9 1.9 2.7 2 1 0 2 2 2 2 Spc24 subunit of Ndc80 Filament PF00038.21 CBY41324.1 - 0.011 15.3 9.3 0.059 12.9 9.4 1.9 1 1 0 1 1 1 0 Intermediate filament protein EF-hand_5 PF13202.6 CBY41324.1 - 0.012 15.0 1.9 0.35 10.4 0.2 2.6 2 0 0 2 2 2 0 EF hand DUF5082 PF16888.5 CBY41324.1 - 0.03 14.6 7.1 0.12 12.6 4.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CALCOCO1 PF07888.11 CBY41324.1 - 0.032 13.1 14.4 0.048 12.5 14.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.22 CBY41324.1 - 0.041 14.1 8.7 0.27 11.5 1.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 CBY41324.1 - 0.07 13.6 12.8 0.11 12.9 12.8 1.2 1 0 0 1 1 1 0 Fez1 DUF4797 PF16051.5 CBY41324.1 - 0.075 13.0 3.8 3 7.9 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) TMF_TATA_bd PF12325.8 CBY41324.1 - 0.11 12.7 11.0 0.56 10.4 6.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding kleA_kleC PF17383.2 CBY41324.1 - 0.27 11.6 3.8 1 9.7 0.2 3.0 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A Golgin_A5 PF09787.9 CBY41324.1 - 0.28 10.6 13.8 0.49 9.8 13.8 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CBY41324.1 - 0.44 10.6 13.4 1.3 9.1 13.4 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CBY41324.1 - 0.45 9.1 4.9 1.1 7.8 4.9 1.4 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 CBY41324.1 - 0.57 10.3 3.1 0.89 9.7 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 CBY41324.1 - 1 8.2 15.0 0.46 9.3 12.6 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.15 CBY41324.1 - 1.1 9.4 5.1 0.26 11.4 1.5 1.7 2 0 0 2 2 1 0 RasGAP C-terminus DUF2730 PF10805.8 CBY41324.1 - 1.1 9.3 4.5 1.6 8.8 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF724 PF05266.14 CBY41324.1 - 1.2 8.9 7.4 0.54 10.1 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 CBY41324.1 - 1.4 8.1 3.9 2.1 7.5 3.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 CBY41324.1 - 1.8 7.8 10.2 4.8 6.5 10.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 CBY41324.1 - 3.1 8.2 6.4 7 7.1 0.5 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 CBY41324.1 - 3.1 6.2 9.7 4.2 5.8 9.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 CBY41324.1 - 3.2 8.4 10.2 8 7.2 4.6 3.3 1 1 2 3 3 3 0 SlyX Atg14 PF10186.9 CBY41324.1 - 3.3 6.7 6.7 5.6 6.0 6.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 CBY41324.1 - 5.1 6.4 15.5 0.33 10.3 7.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.11 CBY41324.1 - 7.3 6.6 14.7 1.9 8.5 8.3 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 CBY41324.1 - 7.4 6.6 16.4 0.91 9.6 5.0 2.5 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 CBY41324.1 - 9.2 6.7 9.4 28 5.2 0.2 2.9 1 1 2 3 3 3 0 Csm1 N-terminal domain Dicty_REP PF05086.12 CBY41325.1 - 0.037 12.0 1.8 0.041 11.9 1.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2141 PF09912.9 CBY41325.1 - 0.047 13.6 0.5 0.52 10.2 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) Mucin PF01456.17 CBY41325.1 - 0.13 12.2 13.9 0.21 11.5 13.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CBY41325.1 - 0.44 10.5 6.9 0.84 9.6 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Collagen PF01391.18 CBY41326.1 - 5.2e-17 61.4 63.6 3.2e-10 39.6 30.7 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Trypsin PF00089.26 CBY41329.1 - 3.9e-48 164.2 2.7 5.1e-48 163.8 2.7 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY41329.1 - 9.4e-06 26.6 0.2 2.1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY41329.1 - 0.18 12.2 0.8 0.3 11.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Epiglycanin_TR PF05647.11 CBY41329.1 - 0.7 9.9 27.5 0.31 11.0 23.4 2.4 1 1 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Trypsin PF00089.26 CBY41330.1 - 1.1e-46 159.5 2.9 1.5e-46 159.0 2.9 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY41330.1 - 3.9e-07 31.1 0.8 3.9e-07 31.1 0.8 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain DUF732 PF05305.14 CBY41330.1 - 0.049 14.0 0.0 0.049 14.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF732) DUF1986 PF09342.11 CBY41330.1 - 0.17 12.3 0.4 0.26 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) Sushi PF00084.20 CBY41330.1 - 3.6 8.2 11.4 0.062 13.9 2.4 2.5 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) Band_7 PF01145.25 CBY41331.1 - 7.2e-33 114.1 2.7 9.3e-33 113.7 2.7 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY41331.1 - 0.00056 19.7 0.1 0.00086 19.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Kinesin_assoc PF16183.5 CBY41331.1 - 0.46 10.6 2.5 0.66 10.1 2.5 1.2 1 0 0 1 1 1 0 Kinesin-associated PDZ PF00595.24 CBY41332.1 - 1e-59 198.8 2.7 1.1e-13 51.3 0.1 5.4 5 0 0 5 5 5 5 PDZ domain PDZ_6 PF17820.1 CBY41332.1 - 3.8e-58 193.2 7.1 6.5e-16 57.9 0.1 5.3 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 CBY41332.1 - 2.3e-30 104.7 5.3 3.2e-05 24.2 0.0 5.5 5 0 0 5 5 5 5 PDZ domain DUF3394 PF11874.8 CBY41332.1 - 3e-05 23.8 0.0 0.55 9.9 0.0 3.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3394) Tom22 PF04281.13 CBY41332.1 - 3 7.6 6.8 6.5 6.5 6.8 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Urocanase PF01175.18 CBY41333.1 - 1e-76 257.3 0.0 1.4e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 CBY41333.1 - 3.3e-52 175.5 0.3 6.4e-52 174.6 0.3 1.5 1 0 0 1 1 1 1 Urocanase N-terminal domain Urocanase_C PF17392.2 CBY41333.1 - 8.3e-05 22.1 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain YcgR PF07317.12 CBY41333.1 - 0.092 12.6 0.0 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar regulator YcgR UDPGP PF01704.18 CBY41334.1 - 8.7e-56 189.3 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBY41334.1 - 0.00041 20.7 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Kelch_6 PF13964.6 CBY41337.1 - 0.0063 16.8 0.6 1.3 9.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CBY41337.1 - 0.027 14.5 4.3 0.42 10.7 0.1 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY41337.1 - 0.5 10.4 3.1 22 5.2 0.0 3.9 4 0 0 4 4 4 0 Kelch motif DUF3871 PF12987.7 CBY41338.1 - 0.048 12.5 0.0 0.054 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) UBZ_FAAP20 PF15750.5 CBY41339.1 - 0.0028 17.6 0.4 0.0075 16.2 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-binding zinc-finger zf-Di19 PF05605.12 CBY41339.1 - 0.026 14.8 1.0 0.026 14.8 1.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding YabA PF06156.13 CBY41339.1 - 0.056 14.1 1.5 0.056 14.1 1.5 1.9 1 1 1 2 2 2 0 Initiation control protein YabA zf-TRAF PF02176.18 CBY41339.1 - 0.13 13.0 7.5 0.18 12.5 5.6 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger zf-TAZ PF02135.16 CBY41339.1 - 0.19 12.2 4.1 0.32 11.5 4.1 1.4 1 0 0 1 1 1 0 TAZ zinc finger zf-C2HC_2 PF13913.6 CBY41339.1 - 0.99 9.4 7.2 1 9.4 2.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CBFB_NFYA PF02045.15 CBY41341.1 - 1.5e-27 96.0 3.8 5e-27 94.3 3.8 2.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B YlzJ PF14035.6 CBY41341.1 - 0.33 11.2 3.4 2.1 8.6 0.2 3.3 3 0 0 3 3 3 0 YlzJ-like protein BTB_2 PF02214.22 CBY41342.1 - 1.1e-06 28.8 0.0 1.4e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain HPIP PF15226.6 CBY41342.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family CBFD_NFYB_HMF PF00808.23 CBY41343.1 - 1.6e-14 53.9 0.7 2.3e-14 53.4 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY41343.1 - 0.00012 22.5 0.2 0.00012 22.5 0.2 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 CBY41343.1 - 0.03 14.4 0.2 0.049 13.7 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region zf-DNL PF05180.12 CBY41345.1 - 3e-30 103.9 0.9 4.1e-30 103.5 0.9 1.2 1 0 0 1 1 1 1 DNL zinc finger PADR1 PF08063.12 CBY41345.1 - 0.07 12.9 0.1 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain Med26 PF08711.11 CBY41346.1 - 1.1e-09 38.1 0.0 4.5e-09 36.2 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_M PF07500.14 CBY41346.1 - 3.7e-05 24.2 2.8 3.7e-05 24.2 2.8 2.8 1 1 1 2 2 2 1 Transcription factor S-II (TFIIS), central domain Lipase_GDSL_3 PF14606.6 CBY41346.1 - 0.018 15.2 0.4 0.052 13.7 0.1 1.8 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family AAA_assoc_C PF09821.9 CBY41346.1 - 0.045 14.3 0.3 0.045 14.3 0.3 2.5 2 1 1 3 3 3 0 C-terminal AAA-associated domain Latarcin PF10279.9 CBY41346.1 - 0.096 13.1 0.3 0.096 13.1 0.3 2.7 2 2 0 2 2 2 0 Latarcin precursor GCIP PF13324.6 CBY41346.1 - 1.8 8.1 5.9 5.1 6.6 5.9 1.7 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Peptidase_M41 PF01434.18 CBY41346.1 - 1.8 8.3 5.7 15 5.3 0.8 2.8 3 0 0 3 3 3 0 Peptidase family M41 XH PF03469.14 CBY41346.1 - 2 8.4 8.9 0.69 9.8 4.8 2.2 2 1 0 2 2 2 0 XH domain V-ATPase_H_C PF11698.8 CBY41347.1 - 0.1 12.7 0.2 0.27 11.3 0.1 1.9 1 1 0 1 1 1 0 V-ATPase subunit H DEAD PF00270.29 CBY41348.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 CBY41348.1 - 0.22 10.6 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Asn_synthase PF00733.21 CBY41349.1 - 1.1e-22 81.2 0.0 1.4e-19 71.0 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CBY41349.1 - 2.1e-13 50.2 0.0 5.4e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CBY41349.1 - 8.1e-09 35.8 0.0 5.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain CBM_X2 PF03442.14 CBY41349.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 EFG_C PF00679.24 CBY41350.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus Sterile PF03015.19 CBY41351.1 - 0.15 12.3 0.0 0.18 12.1 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein Sec23_trunk PF04811.15 CBY41352.1 - 1.2e-63 214.9 0.0 1.9e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBY41352.1 - 1.8e-29 102.3 0.2 2.5e-28 98.7 0.1 2.7 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CBY41352.1 - 1.9e-21 75.8 0.1 8.9e-21 73.7 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CBY41352.1 - 1.8e-15 56.7 8.3 3.6e-15 55.7 8.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBY41352.1 - 1e-11 44.5 0.2 2.8e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Chromo PF00385.24 CBY41355.1 - 3.1e-14 52.6 2.0 3.1e-14 52.6 2.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_2 PF18704.1 CBY41355.1 - 0.22 11.8 7.5 0.15 12.4 1.1 4.1 3 0 0 3 3 3 0 Chromatin organization modifier domain 2 AIRS_C PF02769.22 CBY41359.1 - 1.8e-25 89.9 0.3 2.1e-25 89.7 0.3 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Sulfotransfer_1 PF00685.27 CBY41362.1 - 1.1e-15 57.9 0.0 3.2e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY41362.1 - 7.7e-07 29.7 1.3 0.6 10.4 0.0 3.9 3 1 2 5 5 5 3 Sulfotransferase family Gly_rich PF12810.7 CBY41363.1 - 4.8e-07 29.9 56.7 3.3e-05 23.9 56.7 2.5 1 1 0 1 1 1 1 Glycine rich protein COLFI PF01410.18 CBY41363.1 - 0.00018 20.9 2.9 0.047 13.0 0.5 3.2 2 1 0 2 2 2 2 Fibrillar collagen C-terminal domain Fibrinogen_C PF00147.18 CBY41363.1 - 0.00044 20.1 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Fibrinogen beta and gamma chains, C-terminal globular domain ERM PF00769.19 CBY41363.1 - 0.074 12.9 12.4 0.097 12.5 12.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF724 PF05266.14 CBY41363.1 - 0.13 12.1 5.4 0.25 11.1 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF5344 PF17279.2 CBY41363.1 - 0.32 11.6 3.4 0.59 10.7 3.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) APG6_N PF17675.1 CBY41363.1 - 0.69 10.4 12.2 1 9.9 12.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 CBY41363.1 - 1.2 9.5 7.2 2.2 8.6 7.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 CBY41363.1 - 1.7 9.1 12.4 3.5 8.1 2.4 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HAP1_N PF04849.13 CBY41363.1 - 7.8 5.6 14.7 11 5.2 14.7 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF346 PF03984.13 CBY41363.1 - 8.9 6.2 8.3 1.2 8.9 3.4 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Phospholip_A2_1 PF00068.19 CBY41366.1 - 1.4e-17 64.2 8.7 1.9e-17 63.7 8.7 1.2 1 0 0 1 1 1 1 Phospholipase A2 Rax2 PF12768.7 CBY41367.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Aldedh PF00171.22 CBY41370.1 - 9.1e-129 429.9 0.0 1.1e-128 429.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SIKE PF05769.11 CBY41371.1 - 3.2e-24 85.9 10.1 9e-24 84.4 10.1 1.8 1 0 0 1 1 1 1 SIKE family Tho2 PF11262.8 CBY41371.1 - 0.052 12.8 4.8 2.5 7.2 2.3 2.4 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 LIAS_N PF16881.5 CBY41371.1 - 0.12 12.8 3.4 0.19 12.2 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family BRE1 PF08647.11 CBY41371.1 - 2.4 8.3 12.5 0.72 10.0 2.2 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4661 PF15576.6 CBY41371.1 - 2.8 7.8 6.7 0.86 9.5 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) NYD-SP28_assoc PF14775.6 CBY41371.1 - 6 7.1 8.6 27 5.0 0.4 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain MIF4G PF02854.19 CBY41373.1 - 6.9e-33 114.1 4.5 9.9e-19 67.8 0.2 2.5 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.14 CBY41373.1 - 7.2e-13 49.4 9.0 1.7e-12 48.3 8.4 2.0 1 1 0 1 1 1 1 Up-frameshift suppressor 2 PAXX PF15384.6 CBY41373.1 - 0.048 13.3 0.4 0.087 12.5 0.4 1.4 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 WD40 PF00400.32 CBY41374.1 - 1.7e-33 114.1 18.2 2.5e-09 37.6 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY41374.1 - 1.2e-13 51.1 0.2 0.086 13.1 0.0 6.6 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY41374.1 - 0.00019 20.5 0.9 1.7 7.5 0.1 4.0 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CBY41374.1 - 0.00061 18.6 1.5 0.0063 15.2 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CBY41374.1 - 0.0012 18.3 0.0 0.78 9.0 0.0 3.0 2 1 0 2 2 2 2 WD40-like domain Dus PF01207.17 CBY41376.1 - 0.0019 17.4 0.7 0.0022 17.2 0.7 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PACT_coil_coil PF10495.9 CBY41376.1 - 0.01 16.4 6.0 0.027 15.0 6.0 1.8 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein NIF PF03031.18 CBY41377.1 - 3.4e-52 176.3 0.1 4.3e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase OST3_OST6 PF04756.13 CBY41377.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family BBP1_C PF15272.6 CBY41381.1 - 0.00041 20.2 1.8 0.00055 19.8 1.8 1.2 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal YgbB PF02542.16 CBY41381.1 - 0.012 15.9 0.4 0.015 15.5 0.4 1.1 1 0 0 1 1 1 0 YgbB family DUF919 PF06034.11 CBY41381.1 - 0.025 14.4 0.4 0.057 13.3 0.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cdh1_DBD_1 PF18196.1 CBY41381.1 - 0.075 13.4 0.6 0.13 12.6 0.6 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF5425 PF17472.2 CBY41381.1 - 0.16 12.8 0.3 0.16 12.8 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5425) Pkinase PF00069.25 CBY41382.1 - 7.6e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41382.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Tctex-1 PF03645.13 CBY41385.1 - 4.7e-28 97.4 3.5 5.4e-28 97.3 3.5 1.0 1 0 0 1 1 1 1 Tctex-1 family Phos_pyr_kin PF08543.12 CBY41385.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Peptidase_C12 PF01088.21 CBY41386.1 - 9.2e-56 188.9 0.0 1e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SRP54 PF00448.22 CBY41387.1 - 2.8e-74 249.0 1.4 3.2e-74 248.8 0.1 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CBY41387.1 - 3.4e-18 65.6 1.7 1.1e-17 63.9 1.7 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP_SPB PF02978.19 CBY41387.1 - 1.8e-16 60.5 1.8 1.8e-16 60.5 1.8 4.6 3 2 0 3 3 2 1 Signal peptide binding domain cobW PF02492.19 CBY41387.1 - 2.3e-08 33.8 0.5 1.6e-07 31.1 0.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CBY41387.1 - 0.00018 20.6 0.4 0.0037 16.3 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CBY41387.1 - 0.00079 19.6 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain CbiA PF01656.23 CBY41387.1 - 0.0011 19.0 0.0 0.0068 16.5 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2209 PF09974.9 CBY41387.1 - 0.0033 17.7 0.2 0.0075 16.6 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2209) APS_kinase PF01583.20 CBY41387.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.10 CBY41387.1 - 0.0059 16.1 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 CBY41387.1 - 0.0075 16.7 2.0 0.075 13.4 0.7 3.1 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CBY41387.1 - 0.0086 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 CBY41387.1 - 0.0089 16.0 0.0 0.092 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CBY41387.1 - 0.012 15.7 0.3 0.065 13.3 0.1 2.4 2 1 0 2 2 1 0 50S ribosome-binding GTPase ResIII PF04851.15 CBY41387.1 - 0.015 15.3 0.1 0.043 13.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CBY41387.1 - 0.026 14.9 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CBY41387.1 - 0.029 14.0 0.1 0.068 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 CBY41387.1 - 0.03 14.2 0.1 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CBY41387.1 - 0.037 14.4 0.0 0.2 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBY41387.1 - 0.044 13.1 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CBY41387.1 - 0.049 13.9 0.1 0.26 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain TK PF00265.18 CBY41387.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase Yuri_gagarin PF15934.5 CBY41387.1 - 0.067 13.0 0.1 0.26 11.1 0.1 1.9 1 1 0 1 1 1 0 Yuri gagarin PduV-EutP PF10662.9 CBY41387.1 - 0.086 12.6 0.9 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CBY41387.1 - 0.11 12.3 0.2 3.8 7.3 0.1 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 CBY41387.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CBY41387.1 - 0.15 11.7 0.1 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 CBY41387.1 - 0.23 12.0 1.0 0.74 10.4 0.1 2.4 3 1 0 3 3 2 0 AAA domain Kelch_1 PF01344.25 CBY41388.1 - 8.1e-05 22.1 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 CBY41388.1 - 0.00032 20.6 0.2 0.00037 20.4 0.2 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY41388.1 - 0.00037 20.7 1.3 0.0011 19.2 1.3 1.8 1 1 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 CBY41388.1 - 0.0024 18.1 0.1 0.0026 18.0 0.1 1.1 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY41388.1 - 0.015 15.2 0.7 0.022 14.7 0.6 1.4 1 1 0 1 1 1 0 Kelch motif Kelch_2 PF07646.15 CBY41388.1 - 0.044 13.8 0.8 0.092 12.8 0.7 1.7 1 1 0 1 1 1 0 Kelch motif Nup88 PF10168.9 CBY41389.1 - 0.00043 18.3 0.0 0.00043 18.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore component Glyco_hydro_9 PF00759.19 CBY41392.1 - 2.5e-138 462.0 5.0 3.4e-138 461.5 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 I_LWEQ PF01608.17 CBY41393.1 - 2.6e-45 154.4 4.8 2.6e-45 154.4 4.8 2.4 3 0 0 3 3 3 1 I/LWEQ domain DUF4055 PF13264.6 CBY41393.1 - 2.2 8.4 6.3 0.63 10.2 1.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4055) Fibrinogen_C PF00147.18 CBY41395.1 - 0.00028 20.7 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Apolipoprotein PF01442.18 CBY41395.1 - 0.0047 16.8 4.4 0.12 12.3 0.4 2.2 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF4803 PF16061.5 CBY41395.1 - 0.0047 16.4 0.4 0.0047 16.4 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4803) OmpH PF03938.14 CBY41395.1 - 0.44 10.9 8.5 0.088 13.1 1.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) COG5 PF10392.9 CBY41395.1 - 0.51 10.5 3.4 0.63 10.2 0.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Fib_alpha PF08702.10 CBY41395.1 - 0.57 10.4 6.6 0.066 13.4 1.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 CBY41395.1 - 1.4 9.0 5.5 0.38 10.8 2.0 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PQ-loop PF04193.14 CBY41396.1 - 1.1e-36 124.3 5.2 5.3e-19 67.7 2.6 2.7 2 0 0 2 2 2 2 PQ loop repeat TauE PF01925.19 CBY41396.1 - 0.036 13.7 0.9 0.066 12.8 0.3 1.7 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE LtrA PF06772.11 CBY41396.1 - 0.075 12.2 3.8 0.093 11.9 2.3 1.8 1 1 1 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) Nucleoporin_FG PF13634.6 CBY41398.1 - 0.042 14.7 1.2 0.078 13.8 1.2 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region PHP PF02811.19 CBY41400.1 - 0.035 14.4 0.0 0.09 13.1 0.0 1.8 1 1 0 1 1 1 0 PHP domain RRS1 PF04939.12 CBY41401.1 - 4.3e-45 153.5 10.5 4.3e-45 153.5 10.5 2.3 3 0 0 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) YscJ_FliF PF01514.17 CBY41401.1 - 0.22 11.1 5.3 3.7 7.2 0.2 2.6 3 0 0 3 3 3 0 Secretory protein of YscJ/FliF family RRF PF01765.19 CBY41402.1 - 1.9e-10 41.0 2.3 3.1e-10 40.3 2.3 1.4 1 0 0 1 1 1 1 Ribosome recycling factor ERp29 PF07749.12 CBY41402.1 - 2.5 9.1 9.0 0.45 11.4 3.4 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain DZF PF07528.14 CBY41403.1 - 3.7e-50 170.9 0.0 5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DZF domain Gly-rich_Ago1 PF12764.7 CBY41403.1 - 0.82 10.5 6.4 2.1 9.2 6.4 1.7 1 0 0 1 1 1 0 Glycine-rich region of argonaut Tnp_zf-ribbon_2 PF13842.6 CBY41404.1 - 0.019 15.7 0.3 0.042 14.7 0.3 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RhoGAP PF00620.27 CBY41405.1 - 8.2e-34 116.6 0.0 1.9e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SH3_9 PF14604.6 CBY41405.1 - 5.9e-05 22.8 0.0 0.00028 20.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CBY41405.1 - 0.00046 19.7 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 SH3 domain RNF111_N PF15303.6 CBY41405.1 - 0.011 15.6 1.3 0.011 15.6 1.3 2.3 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Pam16 PF03656.13 CBY41406.1 - 0.00049 20.1 0.2 0.00064 19.7 0.2 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CBY41406.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PET117 PF15786.5 CBY41407.1 - 3.5e-14 52.8 0.8 4.3e-14 52.5 0.8 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF2514 PF10721.9 CBY41407.1 - 0.0021 18.1 0.9 0.0023 18.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) DUF4570 PF15134.6 CBY41407.1 - 0.1 12.6 3.6 0.15 12.1 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) LptF_LptG PF03739.14 CBY41407.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG ATP_bind_1 PF03029.17 CBY41408.1 - 1e-49 169.5 0.2 1.3e-49 169.1 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CBY41408.1 - 0.0064 16.0 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DMAP1 PF05499.12 CBY41408.1 - 0.014 15.3 1.5 0.022 14.7 1.5 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) GTP_EFTU PF00009.27 CBY41408.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBY41408.1 - 0.029 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 CBY41408.1 - 0.033 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase BshC PF10079.9 CBY41408.1 - 0.036 12.8 0.2 0.056 12.2 0.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC cobW PF02492.19 CBY41408.1 - 0.036 13.6 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RPN2_C PF18004.1 CBY41409.1 - 9.6e-42 142.6 7.2 1.7e-41 141.8 7.2 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CBY41409.1 - 1.1e-39 132.8 22.0 1.1e-08 35.1 0.1 8.5 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBY41409.1 - 1.9e-20 73.0 5.7 4.2e-13 49.5 0.0 5.2 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 CBY41409.1 - 0.00013 21.9 1.4 6.8 7.2 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CBY41409.1 - 0.00017 22.0 0.3 3.8 8.1 0.0 4.2 2 1 2 4 4 4 3 HEAT-like repeat TPR_2 PF07719.17 CBY41411.1 - 6.2e-10 38.4 0.4 0.0023 17.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY41411.1 - 9.9e-09 34.7 0.9 1.2e-07 31.2 0.1 2.3 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.28 CBY41411.1 - 1.2e-08 34.4 0.3 0.00012 21.8 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41411.1 - 1.7e-07 30.9 0.2 0.0068 16.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBY41411.1 - 5.7e-05 23.5 1.8 0.15 12.6 0.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY41411.1 - 6e-05 23.5 1.4 5.4 8.1 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 CBY41411.1 - 0.00066 19.0 1.6 0.26 10.5 0.3 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY41411.1 - 0.00066 20.3 0.1 0.0022 18.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY41411.1 - 0.0059 16.7 0.2 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY41411.1 - 0.0062 16.8 0.2 0.02 15.2 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Cytochrom_D1 PF02239.16 CBY41411.1 - 0.092 11.3 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain TPR_7 PF13176.6 CBY41411.1 - 0.12 12.4 2.1 3.1 8.0 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41411.1 - 0.13 12.6 1.1 9.4 6.6 0.1 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBY41411.1 - 0.33 10.9 0.9 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CBY41411.1 - 0.34 11.0 0.1 0.34 11.0 0.1 2.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain 7tm_1 PF00001.21 CBY41412.1 - 0.078 12.3 1.2 0.11 11.8 1.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2970 PF11174.8 CBY41413.1 - 0.0054 16.5 0.0 0.0065 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) zf-RING_UBOX PF13445.6 CBY41414.1 - 8.4e-06 25.7 5.1 8.4e-06 25.7 5.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 CBY41414.1 - 1.4e-05 25.3 13.0 3.9e-05 23.9 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY41414.1 - 0.00078 19.3 10.3 0.00078 19.3 10.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY41414.1 - 0.0015 18.4 17.4 0.0028 17.6 11.1 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY41414.1 - 0.0043 16.9 17.1 0.013 15.4 11.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY41414.1 - 0.0048 16.7 16.8 0.0072 16.2 11.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 CBY41414.1 - 0.0056 16.5 5.7 0.0056 16.5 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CBY41414.1 - 0.0061 16.2 4.0 0.0089 15.6 4.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Enkurin PF13864.6 CBY41414.1 - 0.012 16.0 5.5 0.012 16.0 5.5 2.6 1 1 1 2 2 2 0 Calmodulin-binding zf-RING_4 PF14570.6 CBY41414.1 - 0.018 14.9 13.2 0.17 11.7 7.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY41414.1 - 0.075 12.9 19.0 4.4 7.2 0.4 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Golgin_A5 PF09787.9 CBY41414.1 - 0.078 12.4 16.3 0.12 11.8 16.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 IBR PF01485.21 CBY41414.1 - 0.091 13.0 11.4 0.14 12.4 7.0 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 CBY41414.1 - 0.1 12.7 9.2 0.57 10.2 3.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Fusion_gly PF00523.18 CBY41414.1 - 0.1 10.8 2.9 0.14 10.4 2.9 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 SUKH-3 PF14433.6 CBY41414.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 SUKH-3 immunity protein HMMR_N PF15905.5 CBY41414.1 - 0.16 11.4 14.1 0.23 10.9 14.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Colicin PF01024.19 CBY41414.1 - 0.19 11.6 2.3 0.3 10.9 2.3 1.2 1 0 0 1 1 1 0 Colicin pore forming domain zf-C2H2_jaz PF12171.8 CBY41414.1 - 0.48 10.8 5.7 1.1 9.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YojJ PF10372.9 CBY41414.1 - 0.55 10.4 3.9 1.5 9.0 0.6 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FYVE PF01363.21 CBY41414.1 - 0.69 10.1 9.1 1.3 9.2 3.7 2.3 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 CBY41414.1 - 0.79 9.9 9.5 4.2 7.6 6.9 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sulfatase_C PF14707.6 CBY41414.1 - 0.81 10.4 5.3 1.3 9.8 0.7 2.6 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF2703 PF10865.8 CBY41414.1 - 0.88 9.8 6.7 0.7 10.1 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) V_ATPase_I PF01496.19 CBY41414.1 - 2.1 6.2 8.3 2.5 5.9 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CBY41414.1 - 2.7 6.8 15.7 4.1 6.2 15.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.10 CBY41414.1 - 3.2 8.1 13.5 45 4.4 13.4 2.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Zn-C2H2_12 PF18112.1 CBY41414.1 - 3.3 8.2 9.0 12 6.5 0.5 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain CENP-H PF05837.12 CBY41414.1 - 7.3 7.0 11.4 18 5.8 11.2 1.8 1 1 0 1 1 1 0 Centromere protein H (CENP-H) PAP_assoc PF03828.19 CBY41415.1 - 1.1e-07 31.9 0.2 2.7e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBY41415.1 - 9.8e-06 25.8 0.1 5.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBY41415.1 - 0.0065 16.5 0.0 0.045 13.9 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Arylsulfotran_N PF17425.2 CBY41415.1 - 0.074 13.1 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain IGFL PF14653.6 CBY41416.1 - 0.029 14.3 3.1 0.04 13.9 3.1 1.3 1 0 0 1 1 1 0 Insulin growth factor-like family FBA_2 PF07735.17 CBY41416.1 - 0.11 12.7 0.4 0.17 12.0 0.4 1.5 1 1 0 1 1 1 0 F-box associated Insulin PF00049.18 CBY41416.1 - 0.49 11.4 8.9 1.1 10.3 0.2 2.2 1 1 1 2 2 2 0 Insulin/IGF/Relaxin family DUF5522 PF17653.1 CBY41416.1 - 0.82 9.7 9.5 0.62 10.1 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5522) C2 PF00168.30 CBY41417.1 - 6.9e-12 45.6 0.0 9.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF5490 PF17593.2 CBY41417.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5490) PTPLA PF04387.14 CBY41418.1 - 5.2e-43 146.6 8.0 6.6e-43 146.3 8.0 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PsbY PF06298.11 CBY41418.1 - 2.8 7.9 5.8 32 4.5 4.9 3.1 2 1 0 2 2 2 0 Photosystem II protein Y (PsbY) Phage_FRD3 PF05798.11 CBY41420.1 - 0.019 15.2 0.1 0.027 14.8 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage FRD3 protein UQ_con PF00179.26 CBY41421.1 - 0.0069 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY41421.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 CBY41422.1 - 2.5e-09 36.9 0.9 4.1e-09 36.2 0.9 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY41422.1 - 0.018 14.9 0.2 0.087 12.7 0.1 2.0 2 0 0 2 2 2 0 UEV domain gp45-slide_C PF09116.10 CBY41422.1 - 0.026 14.6 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal Dus PF01207.17 CBY41424.1 - 1.2e-67 228.2 0.0 1.5e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 CBY41424.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 CBY41424.1 - 0.018 14.8 0.2 0.054 13.3 0.0 1.7 1 1 1 2 2 2 0 SOR/SNZ family DUF2102 PF09875.9 CBY41424.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) G3P_antiterm PF04309.12 CBY41424.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Laminin_II PF06009.12 CBY41424.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain II Toxin_13 PF07822.11 CBY41425.1 - 3.6 7.8 9.4 21 5.3 5.7 3.1 1 1 2 3 3 3 0 Neurotoxin B-IV-like protein SIP1 PF04938.12 CBY41426.1 - 1.1e-05 25.3 0.3 1.4e-05 25.0 0.3 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) POP1 PF06978.11 CBY41426.1 - 0.061 13.3 0.6 0.061 13.3 0.6 1.5 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 SIP1 PF04938.12 CBY41427.1 - 9.1e-11 41.9 0.6 1e-10 41.7 0.6 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) P5CR_dimer PF14748.6 CBY41428.1 - 4.8e-36 123.1 2.3 9.4e-36 122.2 2.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBY41428.1 - 5.3e-16 59.0 0.1 1.7e-15 57.4 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Regulator_TrmB PF11495.8 CBY41428.1 - 0.00089 18.5 0.1 0.0012 18.1 0.1 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PDH PF02153.17 CBY41428.1 - 0.044 12.8 0.1 0.1 11.6 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase UPRTase PF14681.6 CBY41428.1 - 0.063 12.7 0.3 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase NAD_Gly3P_dh_N PF01210.23 CBY41428.1 - 1 9.4 5.1 0.19 11.7 0.2 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.16 CBY41429.1 - 1.5e-20 73.4 18.5 1.5e-20 73.4 18.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CBY41429.1 - 6.6e-08 31.3 6.5 1.2e-07 30.4 6.5 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4567 PF15131.6 CBY41429.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) Phage_holin_3_6 PF07332.11 CBY41429.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.6 4 2 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1189 PF06691.11 CBY41429.1 - 2.9 7.4 10.0 0.2 11.2 4.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1189) Pkinase_Tyr PF07714.17 CBY41430.1 - 3.6e-45 154.3 0.0 2.9e-42 144.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY41430.1 - 1.4e-28 100.0 0.2 5.9e-26 91.4 0.0 3.1 2 1 0 3 3 3 1 Protein kinase domain Kdo PF06293.14 CBY41430.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY41430.1 - 0.17 10.6 1.8 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Homeodomain PF00046.29 CBY41431.1 - 0.00047 19.9 1.1 0.0013 18.5 1.1 1.7 1 0 0 1 1 1 1 Homeodomain FAM176 PF14851.6 CBY41431.1 - 0.03 14.0 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Prismane PF03063.20 CBY41432.1 - 1.7 7.3 5.7 1.9 7.1 5.7 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Folliculin PF11704.8 CBY41432.1 - 4.1 7.2 9.3 5 7.0 9.3 1.3 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4407 PF14362.6 CBY41432.1 - 4.6 6.5 10.9 5.8 6.2 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 CBY41433.1 - 4e-35 120.3 3.4 1.7e-17 63.8 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY41433.1 - 4.5e-24 84.5 0.7 4.7e-11 43.0 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY41433.1 - 2.9e-22 78.1 0.5 2.2e-06 27.9 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBY41433.1 - 2.9e-16 57.9 0.0 7.5e-07 29.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CBY41433.1 - 2.6e-15 56.3 0.2 1.3e-09 38.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CbiC PF02570.15 CBY41435.1 - 0.095 12.3 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF2570 PF10828.8 CBY41435.1 - 0.2 11.5 10.2 4.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) HAUS6_N PF14661.6 CBY41435.1 - 2.8 7.4 6.2 0.87 9.1 3.4 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF3543 PF12063.8 CBY41436.1 - 4.5e-07 29.5 0.4 9.2e-07 28.5 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CBY41436.1 - 0.0002 20.8 0.0 0.00046 19.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Vta1 PF04652.16 CBY41436.1 - 0.006 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Vta1 like SesA PF17107.5 CBY41436.1 - 0.053 13.7 0.1 6.7 6.9 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Pap_E4 PF02711.14 CBY41436.1 - 0.56 11.2 5.9 0.78 10.7 0.1 2.7 2 0 0 2 2 2 0 E4 protein MH2 PF03166.14 CBY41437.1 - 1.7e-29 103.4 1.7 3.6e-29 102.3 1.7 1.6 1 0 0 1 1 1 1 MH2 domain MH1 PF03165.16 CBY41437.1 - 5.5e-09 36.2 0.8 4.3e-08 33.3 0.8 2.3 1 1 0 1 1 1 1 MH1 domain DuoxA PF10204.9 CBY41439.1 - 0.0071 15.4 2.1 0.0086 15.1 2.1 1.1 1 0 0 1 1 1 1 Dual oxidase maturation factor Carn_acyltransf PF00755.20 CBY41441.1 - 6.8e-18 64.6 0.0 7.4e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FeoB_associated PF12669.7 CBY41443.1 - 0.072 13.5 1.1 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Troponin-I_N PF11636.8 CBY41444.1 - 0.025 14.5 0.3 0.062 13.3 0.3 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF5319 PF17252.2 CBY41444.1 - 0.025 14.8 0.1 4.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5319) Rad50_zn_hook PF04423.14 CBY41444.1 - 7.7 6.4 9.2 10 6.0 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Med26 PF08711.11 CBY41445.1 - 6.1e-13 48.6 0.2 1.8e-12 47.1 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.25 CBY41446.1 - 3e-57 194.0 0.0 3.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41446.1 - 9e-26 90.7 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY41446.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Cofac_haem_bdg PF04187.13 CBY41446.1 - 0.065 13.2 0.3 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN Pkinase_fungal PF17667.1 CBY41446.1 - 0.065 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CBY41446.1 - 0.082 12.8 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY41446.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CBY41446.1 - 0.12 11.7 0.3 0.21 10.9 0.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L31e PF01198.19 CBY41447.1 - 4.2e-38 129.4 2.6 4.2e-38 129.4 2.6 1.6 1 1 1 2 2 2 1 Ribosomal protein L31e F_actin_cap_B PF01115.17 CBY41448.1 - 1.3e-94 316.3 0.0 1.7e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Band_7 PF01145.25 CBY41448.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Tmemb_14 PF03647.13 CBY41449.1 - 1.3e-14 54.6 7.9 1.6e-14 54.4 7.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C PigN PF04987.14 CBY41449.1 - 0.014 14.3 4.1 0.018 13.9 4.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TctB PF07331.11 CBY41449.1 - 3.8 7.8 10.0 12 6.2 10.0 1.7 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family NAC PF01849.18 CBY41450.1 - 2.4e-17 62.6 2.0 1.3e-15 57.1 1.4 2.3 2 0 0 2 2 2 2 NAC domain GDA1_CD39 PF01150.17 CBY41451.1 - 1.4e-50 172.3 0.0 2e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EF-hand_1 PF00036.32 CBY41453.1 - 0.097 12.3 0.2 0.21 11.2 0.2 1.7 1 1 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 CBY41453.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Ras PF00071.22 CBY41456.1 - 5.9e-57 191.8 0.1 6.9e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY41456.1 - 6e-35 120.1 0.0 1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY41456.1 - 3.9e-16 59.0 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY41456.1 - 2.2e-07 30.9 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY41456.1 - 1.6e-06 27.8 0.0 3e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY41456.1 - 1.8e-06 27.5 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY41456.1 - 6.2e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY41456.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CBY41456.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CBY41456.1 - 0.026 14.0 0.5 0.042 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CBY41456.1 - 0.027 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY41456.1 - 0.045 13.5 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBY41456.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 CBY41456.1 - 0.067 12.3 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CBY41456.1 - 0.14 12.7 0.2 0.27 11.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF4023 PF13215.6 CBY41456.1 - 0.47 10.5 5.7 0.82 9.7 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) HTH_Tnp_IS630 PF01710.16 CBY41457.1 - 0.027 14.5 2.2 0.032 14.3 0.1 2.1 2 1 0 2 2 2 0 Transposase DUF1349 PF07081.11 CBY41461.1 - 0.045 13.5 0.6 0.062 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1349) DUF3105 PF11303.8 CBY41461.1 - 0.084 13.0 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) I-set PF07679.16 CBY41466.1 - 1.1e-37 127.9 0.0 1.1e-15 57.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY41466.1 - 2.1e-27 95.5 0.0 1.7e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CBY41466.1 - 4.8e-16 58.7 0.1 0.00021 21.4 0.0 3.2 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY41466.1 - 1.7e-13 50.7 0.0 3.8e-06 27.2 0.0 3.3 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY41466.1 - 4.1e-10 39.8 3.2 0.54 10.4 0.1 5.1 3 3 1 4 4 4 4 Immunoglobulin V-set domain Izumo-Ig PF16706.5 CBY41466.1 - 2.4e-06 27.5 0.3 0.095 12.8 0.0 3.2 3 0 0 3 3 3 2 Izumo-like Immunoglobulin domain C2-set_2 PF08205.12 CBY41466.1 - 0.0013 18.8 0.2 4.4 7.4 0.0 3.4 3 0 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Big_7 PF17957.1 CBY41466.1 - 0.0024 18.6 8.3 0.0075 17.0 0.1 3.6 3 1 0 3 3 3 1 Bacterial Ig domain Ig_4 PF16680.5 CBY41466.1 - 0.024 14.9 0.0 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain bMG6 PF17962.1 CBY41466.1 - 0.14 12.3 0.9 2.5 8.3 0.1 2.9 3 0 0 3 3 3 0 Bacterial macroglobulin domain 6 MBG_2 PF18676.1 CBY41466.1 - 0.17 12.5 6.9 13 6.5 0.8 3.6 3 0 0 3 3 3 0 MBG domain (YGX type) Tropomyosin PF00261.20 CBY41467.1 - 1.5e-27 96.5 53.9 1.7e-27 96.3 53.9 1.0 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CBY41467.1 - 1.7e-11 44.4 52.5 2e-06 28.0 20.0 3.3 1 1 0 2 2 2 2 Tropomyosin like DHR10 PF18595.1 CBY41467.1 - 2.5e-05 24.3 51.7 0.0038 17.3 11.6 3.7 1 1 2 3 3 3 2 Designed helical repeat protein 10 domain GAS PF13851.6 CBY41467.1 - 4.1e-05 23.0 41.4 0.035 13.4 20.5 3.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 CBY41467.1 - 0.0002 21.5 40.5 0.072 13.3 6.7 4.0 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding ERM PF00769.19 CBY41467.1 - 0.00051 19.9 44.2 0.00057 19.8 43.5 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family CENP-Q PF13094.6 CBY41467.1 - 0.00053 20.2 5.9 0.00053 20.2 5.9 4.0 1 1 3 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit MCC-bdg_PDZ PF10506.9 CBY41467.1 - 0.0015 18.5 18.5 0.008 16.2 2.0 4.3 3 2 1 4 4 4 1 PDZ domain of MCC-2 bdg protein for Usher syndrome CLZ PF16526.5 CBY41467.1 - 0.0015 18.8 34.8 0.023 15.0 7.8 4.1 3 3 1 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 CBY41467.1 - 0.0016 18.9 40.8 0.0096 16.4 16.7 2.6 1 1 1 2 2 2 1 Fez1 PKcGMP_CC PF16808.5 CBY41467.1 - 0.0053 16.6 2.2 0.0053 16.6 2.2 4.8 5 2 1 6 6 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CENP-F_leu_zip PF10473.9 CBY41467.1 - 0.0078 16.2 46.8 1 9.4 7.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 CBY41467.1 - 0.0092 16.1 4.1 0.0092 16.1 4.1 5.7 1 1 4 6 6 6 1 Centrosome localisation domain of PPC89 BRE1 PF08647.11 CBY41467.1 - 0.047 13.8 36.6 0.13 12.4 3.3 4.1 1 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase Prefoldin PF02996.17 CBY41467.1 - 0.055 13.4 31.2 0.22 11.4 3.7 4.6 2 2 0 4 4 4 0 Prefoldin subunit APG6_N PF17675.1 CBY41467.1 - 0.069 13.7 55.1 0.15 12.6 15.6 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_13 PF13166.6 CBY41467.1 - 0.076 11.7 33.4 0.18 10.4 19.8 2.1 1 1 1 2 2 2 0 AAA domain Leu_zip PF15294.6 CBY41467.1 - 0.079 12.5 36.3 0.02 14.4 26.7 2.1 1 1 1 2 2 2 0 Leucine zipper XhlA PF10779.9 CBY41467.1 - 0.084 13.1 35.2 0.19 11.9 3.2 4.9 3 2 1 5 5 5 0 Haemolysin XhlA DUF3450 PF11932.8 CBY41467.1 - 0.1 11.9 40.3 0.21 10.8 9.7 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 CBY41467.1 - 0.14 12.3 47.8 1.3 9.2 15.6 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Nsp1_C PF05064.13 CBY41467.1 - 0.19 11.6 23.5 0.14 12.0 2.8 3.5 2 1 1 3 3 3 0 Nsp1-like C-terminal region Lebercilin PF15619.6 CBY41467.1 - 0.2 11.3 43.5 0.41 10.3 15.0 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 CBY41467.1 - 0.23 11.9 27.4 0.056 13.9 6.9 3.6 1 1 2 3 3 3 0 Type III cell invasion protein SipB TPR_MLP1_2 PF07926.12 CBY41467.1 - 0.39 10.8 50.0 0.068 13.2 21.2 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 CBY41467.1 - 0.4 10.2 39.4 0.41 10.2 8.1 3.0 1 1 2 3 3 3 0 PspA/IM30 family Striatin PF08232.12 CBY41467.1 - 0.49 11.0 30.1 0.16 12.5 16.5 2.4 1 1 1 2 2 2 0 Striatin family DUF1664 PF07889.12 CBY41467.1 - 0.5 10.4 23.5 0.79 9.8 2.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBY41467.1 - 0.57 9.0 46.1 0.072 12.0 20.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein EzrA PF06160.12 CBY41467.1 - 0.61 8.2 37.8 0.0065 14.7 17.4 2.5 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 CBY41467.1 - 0.87 9.7 42.9 1.4 9.0 6.6 3.9 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 CBY41467.1 - 0.96 10.1 36.4 0.39 11.3 8.6 4.8 1 1 3 5 5 5 0 Bone marrow stromal antigen 2 bZIP_1 PF00170.21 CBY41467.1 - 1.1 9.4 21.9 0.31 11.2 1.4 5.3 2 2 2 5 5 5 0 bZIP transcription factor DASH_Hsk3 PF08227.11 CBY41467.1 - 1.1 9.6 8.9 7.8 7.0 0.1 4.6 5 1 1 6 6 3 0 DASH complex subunit Hsk3 like TMF_DNA_bd PF12329.8 CBY41467.1 - 1.4 9.0 49.2 0.23 11.5 8.2 4.7 1 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 CBY41467.1 - 1.5 8.2 42.8 0.73 9.3 12.0 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 CBY41467.1 - 1.5 8.5 35.1 6.1 6.5 19.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 CBY41467.1 - 2.3 8.9 41.8 8.4 7.1 8.1 4.1 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HrpB7 PF09486.10 CBY41467.1 - 2.5 8.5 38.7 2.8 8.3 10.2 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 CBY41467.1 - 2.6 8.4 46.2 0.44 10.9 12.4 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 CBY41467.1 - 2.7 7.8 40.0 0.057 13.3 20.8 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 CBY41467.1 - 4.4 7.1 35.9 3.5 7.4 7.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) THOC7 PF05615.13 CBY41467.1 - 4.5 7.6 41.7 0.074 13.3 10.4 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 HOOK PF05622.12 CBY41467.1 - 4.7 5.2 43.6 1.2 7.2 10.2 2.3 1 1 1 2 2 2 0 HOOK protein DUF3584 PF12128.8 CBY41467.1 - 4.8 4.6 43.1 1.3e+03 -3.4 43.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 CBY41467.1 - 4.9 7.5 38.4 2.3 8.6 7.0 3.3 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) CALCOCO1 PF07888.11 CBY41467.1 - 5.1 5.9 43.5 0.42 9.4 27.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like PRKG1_interact PF15898.5 CBY41467.1 - 5.2 8.0 40.6 3.9 8.4 11.0 4.1 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 CBY41467.1 - 6.3 7.0 23.7 3.4 7.9 9.1 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBY41467.1 - 6.5 5.9 27.0 9.5 5.4 6.2 2.9 1 1 2 3 3 3 0 TMPIT-like protein FPP PF05911.11 CBY41467.1 - 7.6 4.6 40.1 1.6 6.8 25.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3037 PF11236.8 CBY41467.1 - 9.9 6.6 14.4 2.2 8.7 1.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) Helicase_C PF00271.31 CBY41468.1 - 6.2e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRICHOS PF04089.14 CBY41468.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 BRICHOS domain SNF2_N PF00176.23 CBY41469.1 - 8.4e-51 172.7 0.2 1.3e-50 172.1 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CBY41469.1 - 1e-10 41.9 0.0 2.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBY41469.1 - 0.00027 20.7 0.1 0.039 13.6 0.0 2.2 2 0 0 2 2 2 2 SWI2/SNF2 ATPase CobA_CobO_BtuR PF02572.15 CBY41469.1 - 0.0098 16.2 0.0 0.35 11.1 0.0 2.7 2 1 1 3 3 3 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP GTP-bdg_M PF16360.5 CBY41469.1 - 0.01 16.4 0.7 0.96 10.1 0.0 2.5 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region EF-hand_13 PF17958.1 CBY41470.1 - 5.3e-27 93.5 0.0 1.5e-25 88.8 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CBY41470.1 - 4.5e-14 52.6 2.0 5.6e-14 52.3 0.4 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY41470.1 - 0.0003 20.5 0.2 0.0054 16.6 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY41470.1 - 0.00056 19.3 1.5 0.0044 16.5 0.4 3.0 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CBY41470.1 - 0.00088 18.7 0.3 0.00088 18.7 0.3 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBY41470.1 - 0.054 13.4 0.4 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair CP2 PF04516.15 CBY41471.1 - 4.3e-33 114.5 0.0 6.4e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor GAGA_bind PF06217.12 CBY41473.1 - 4.4 7.5 7.7 8.4 6.6 7.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family ALG3 PF05208.13 CBY41474.1 - 1.3e-130 436.0 23.7 1.5e-130 435.8 23.7 1.0 1 0 0 1 1 1 1 ALG3 protein DUF3456 PF11938.8 CBY41476.1 - 6.7e-06 26.7 7.1 0.0037 17.8 0.2 2.8 2 1 1 3 3 3 2 TLR4 regulator and MIR-interacting MSAP EGF_2 PF07974.13 CBY41476.1 - 0.00027 21.3 16.1 0.00027 21.3 16.1 3.8 3 0 0 3 3 3 1 EGF-like domain Laminin_EGF PF00053.24 CBY41476.1 - 0.016 15.4 13.5 0.016 15.4 13.5 4.5 2 1 2 4 4 4 0 Laminin EGF domain PS_Dcarbxylase PF02666.15 CBY41477.1 - 6.3e-17 61.8 0.0 8.4e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Kelch_4 PF13418.6 CBY41479.1 - 4.1e-06 26.7 0.2 0.076 13.0 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY41479.1 - 0.0093 15.9 0.1 0.76 9.9 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CBY41479.1 - 0.012 15.9 1.2 2.4 8.6 0.0 2.4 1 1 1 2 2 2 0 Kelch motif Kelch_5 PF13854.6 CBY41479.1 - 0.1 12.6 0.4 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Kelch motif EGF PF00008.27 CBY41481.1 - 6.3e-38 128.7 114.7 4.7e-06 26.8 6.2 9.0 9 0 0 9 9 9 8 EGF-like domain hEGF PF12661.7 CBY41481.1 - 7.5e-26 89.8 109.6 5.3e-07 30.0 4.6 10.2 10 0 0 10 10 10 8 Human growth factor-like EGF EGF_2 PF07974.13 CBY41481.1 - 1.2e-16 60.8 127.5 0.0012 19.1 2.3 8.6 9 0 0 9 9 9 8 EGF-like domain EGF_3 PF12947.7 CBY41481.1 - 2.9e-11 43.3 92.1 0.014 15.5 0.2 10.0 5 4 4 9 9 9 8 EGF domain EGF_CA PF07645.15 CBY41481.1 - 1.1e-08 35.2 126.5 0.0064 16.7 8.8 8.5 5 2 3 8 8 8 4 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY41481.1 - 7.5e-06 26.1 95.2 0.25 11.6 5.2 9.6 4 3 5 9 9 9 6 Coagulation Factor Xa inhibitory site cEGF PF12662.7 CBY41481.1 - 0.01 15.8 4.6 0.01 15.8 4.6 10.5 11 1 0 11 11 11 5 Complement Clr-like EGF-like Laminin_EGF PF00053.24 CBY41481.1 - 0.024 14.8 91.2 2.1 8.6 3.9 8.4 2 2 5 8 8 8 0 Laminin EGF domain TPR_1 PF00515.28 CBY41482.1 - 0.015 15.1 0.9 0.015 15.1 0.9 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBY41482.1 - 0.1 12.8 3.9 0.26 11.5 0.8 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY41483.1 - 4.3e-11 42.1 4.8 0.00044 19.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY41483.1 - 9.4e-10 37.9 3.6 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41483.1 - 1.2e-06 28.7 0.0 0.08 13.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41483.1 - 6.4e-06 26.0 5.4 0.00027 20.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY41483.1 - 4.6e-05 23.8 0.0 0.013 16.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 CBY41483.1 - 0.00017 22.1 0.3 0.0015 19.1 0.1 2.7 1 1 1 2 2 2 1 Sel1 repeat TPR_16 PF13432.6 CBY41483.1 - 0.0002 21.9 0.0 0.5 11.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY41483.1 - 0.0073 16.5 0.1 2.2 8.6 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY41483.1 - 0.0094 16.3 0.0 0.55 10.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY41483.1 - 0.012 15.6 0.3 0.86 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3919 PF13057.6 CBY41483.1 - 0.014 15.0 0.7 0.026 14.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) MIT PF04212.18 CBY41483.1 - 0.016 15.2 1.6 3.8 7.7 0.4 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CBY41483.1 - 0.024 15.1 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY41483.1 - 0.028 14.1 3.1 0.22 11.2 1.6 2.8 2 1 0 2 2 2 0 TPR repeat DUF4446 PF14584.6 CBY41483.1 - 0.049 13.6 0.4 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) GramPos_pilinBB PF16569.5 CBY41483.1 - 0.061 14.1 0.3 0.12 13.2 0.3 1.5 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain LysM PF01476.20 CBY41486.1 - 0.00022 21.2 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain HRDC PF00570.23 CBY41486.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 HRDC domain UPF0561 PF10573.9 CBY41487.1 - 0.055 13.6 0.1 4.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 CUE PF02845.16 CBY41488.1 - 1.2e-05 24.9 0.1 2.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain Pox_A3L PF05288.11 CBY41488.1 - 0.21 11.6 1.7 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A3L Protein DUF960 PF06124.11 CBY41488.1 - 1.1 9.9 4.7 0.28 11.9 0.7 2.0 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Importin_rep_6 PF18829.1 CBY41488.1 - 2.1 8.5 6.6 2 8.6 0.0 3.0 2 1 0 2 2 2 0 Importin repeat 6 DDT PF02791.17 CBY41489.1 - 1.7e-08 34.7 3.4 2.6e-07 30.9 2.0 2.4 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 CBY41489.1 - 1.8e-07 31.5 3.5 1.8e-07 31.5 3.5 3.1 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 CBY41489.1 - 5.3e-05 23.0 8.4 0.00011 22.0 8.4 1.5 1 0 0 1 1 1 1 PHD-finger ORC6 PF05460.13 CBY41489.1 - 0.01 15.2 13.5 0.027 13.8 13.5 1.6 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WHIM1 PF15612.6 CBY41489.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Prok-RING_1 PF14446.6 CBY41489.1 - 3.8 7.5 9.0 0.41 10.6 4.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 CBY41489.1 - 8.8 6.0 10.0 0.12 11.9 2.7 1.8 2 0 0 2 2 2 0 PHD-finger YccV-like PF08755.11 CBY41490.1 - 0.015 15.8 0.0 0.035 14.6 0.0 1.7 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Ion_trans PF00520.31 CBY41492.1 - 7.9e-41 139.9 10.9 9.4e-41 139.7 10.9 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 CBY41492.1 - 4.6e-12 45.7 9.8 1.1e-11 44.6 9.8 1.6 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 CBY41492.1 - 0.079 11.6 8.1 0.018 13.8 3.4 1.9 1 1 1 2 2 2 0 Polycystin cation channel DUF4491 PF14898.6 CBY41492.1 - 3.3 8.2 6.7 0.43 11.1 1.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) BET PF17035.5 CBY41493.1 - 0.032 14.4 1.7 0.089 13.0 0.1 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation RNA_polI_A14 PF08203.11 CBY41493.1 - 0.15 12.8 0.5 0.39 11.5 0.5 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Homeobox_KN PF05920.11 CBY41495.1 - 1.5e-14 53.6 0.1 3.6e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CBY41495.1 - 1.1e-06 28.4 1.9 1.2e-06 28.3 0.2 1.9 2 0 0 2 2 2 1 Homeodomain Integrase_H2C2 PF17921.1 CBY41496.1 - 4.7e-05 23.4 1.4 8.1e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 Integrase zinc binding domain Cyclin_N PF00134.23 CBY41499.1 - 1.3e-13 50.8 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CBY41499.1 - 1e-12 48.7 0.1 1.5e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin Methyltransf_23 PF13489.6 CBY41501.1 - 2.8e-12 46.8 0.0 3.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY41501.1 - 8.8e-06 26.3 0.0 1.7e-05 25.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY41501.1 - 7e-05 23.5 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY41501.1 - 9.1e-05 23.0 0.0 0.00037 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY41501.1 - 0.0026 17.6 0.1 0.0035 17.1 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain CorA PF01544.18 CBY41502.1 - 3 7.1 9.3 9.2 5.5 4.6 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein U3_assoc_6 PF08640.11 CBY41502.1 - 4 7.6 8.6 1.7 8.8 0.2 3.4 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 HSBP1 PF06825.12 CBY41502.1 - 6.5 6.7 9.1 2.5 8.0 1.7 3.4 3 1 0 3 3 3 0 Heat shock factor binding protein 1 PLAT PF01477.23 CBY41503.1 - 1.4e-09 38.6 0.0 1.5e-09 38.4 0.0 1.0 1 0 0 1 1 1 1 PLAT/LH2 domain RC-P840_PscD PF10657.9 CBY41503.1 - 0.022 14.9 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD Meckelin PF09773.9 CBY41504.1 - 0.018 13.2 0.8 0.025 12.7 0.8 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Cadherin_C_2 PF16492.5 CBY41504.1 - 0.029 15.1 4.7 20 6.0 5.6 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal MARVEL PF01284.23 CBY41504.1 - 1.5 8.8 18.6 0.16 12.0 11.5 2.0 1 1 1 2 2 2 0 Membrane-associating domain LapA_dom PF06305.11 CBY41504.1 - 1.8 8.4 8.5 2.3 8.1 1.3 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Phospholip_A2_1 PF00068.19 CBY41505.1 - 4.3e-17 62.6 4.4 4.3e-17 62.6 4.4 1.5 2 0 0 2 2 2 1 Phospholipase A2 ParcG PF10274.9 CBY41507.1 - 2.6e-80 268.9 0.0 2.9e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DUF3456 PF11938.8 CBY41509.1 - 9.6e-06 26.2 2.9 0.00024 21.6 0.6 2.4 1 1 0 2 2 2 2 TLR4 regulator and MIR-interacting MSAP adh_short PF00106.25 CBY41510.1 - 1.4e-51 174.8 1.9 1.7e-51 174.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY41510.1 - 1.2e-36 126.4 2.3 1.5e-36 126.1 2.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY41510.1 - 3.1e-13 50.0 0.5 4.5e-13 49.5 0.5 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 CBY41510.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY41510.1 - 0.024 14.1 0.3 0.036 13.5 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GOLGA2L5 PF15070.6 CBY41511.1 - 0.0011 17.7 6.3 0.0015 17.3 6.3 1.3 1 1 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 HALZ PF02183.18 CBY41511.1 - 0.0069 16.6 3.1 0.011 16.0 0.6 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper Baculo_LEF5 PF04838.12 CBY41511.1 - 0.021 14.8 1.3 0.021 14.8 1.3 1.5 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 DUF4803 PF16061.5 CBY41511.1 - 0.048 13.1 3.0 2.3 7.6 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4803) Wbp11 PF09429.10 CBY41511.1 - 0.064 13.7 1.9 0.064 13.7 1.9 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 TPR_MLP1_2 PF07926.12 CBY41511.1 - 0.088 12.9 10.7 0.056 13.5 1.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 CBY41511.1 - 0.091 13.3 4.1 0.11 13.0 3.1 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 CBY41511.1 - 0.11 11.8 3.5 0.13 11.6 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3452 PF11934.8 CBY41511.1 - 0.14 11.7 2.3 0.98 9.0 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Swi5 PF07061.11 CBY41511.1 - 0.19 11.8 4.2 0.2 11.8 0.5 2.2 2 0 0 2 2 2 0 Swi5 TMPIT PF07851.13 CBY41511.1 - 0.44 9.7 6.6 0.073 12.3 2.0 1.7 2 0 0 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 CBY41511.1 - 0.57 9.9 3.7 1.2 8.8 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 CBY41511.1 - 0.9 10.5 10.1 0.077 13.9 2.9 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain SLATT_1 PF18181.1 CBY41511.1 - 1.2 9.1 5.1 11 6.0 1.2 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Atg14 PF10186.9 CBY41511.1 - 1.2 8.1 7.8 1.6 7.8 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 CBY41511.1 - 2.6 8.6 13.4 0.064 13.7 3.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB MAR_sialic_bdg PF10564.9 CBY41512.1 - 2.9e-58 193.9 24.5 7.6e-20 70.8 0.2 5.3 5 1 0 5 5 5 4 Sialic-acid binding micronemal adhesive repeat Axin_b-cat_bind PF08833.10 CBY41512.1 - 0.072 13.2 0.8 27 4.9 0.0 3.8 4 0 0 4 4 4 0 Axin beta-catenin binding domain CCDC23 PF15674.5 CBY41512.1 - 0.15 12.1 0.0 9.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 23 DDHD PF02862.17 CBY41512.1 - 0.19 11.9 3.5 0.26 11.4 3.5 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CBY41512.1 - 0.21 10.3 2.3 0.37 9.5 2.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Apt1 PF10351.9 CBY41512.1 - 2 7.2 7.7 2.6 6.8 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CBY41512.1 - 2 7.4 7.3 3 6.9 7.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RIFIN PF02009.16 CBY41512.1 - 3.7 7.4 18.9 6.5 6.6 18.9 1.4 1 0 0 1 1 1 0 Rifin Trypsin PF00089.26 CBY41513.1 - 1.5e-12 47.8 0.3 1.9e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 Trypsin Sulfotransfer_1 PF00685.27 CBY41514.1 - 7.7e-11 42.0 1.3 1.8e-08 34.2 1.3 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY41514.1 - 7e-07 29.8 0.3 0.00014 22.3 0.1 2.1 1 1 0 2 2 2 2 Sulfotransferase family tRNA-synt_1c PF00749.21 CBY41516.1 - 4.5e-73 245.9 0.0 5.8e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBY41516.1 - 1.4e-35 122.7 0.2 2.6e-35 121.9 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain RGS PF00615.19 CBY41519.1 - 5.7e-06 26.6 0.3 8.8e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3613 PF12266.8 CBY41519.1 - 0.019 14.7 0.5 0.04 13.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) FANCI_S3 PF14677.6 CBY41519.1 - 0.063 13.0 0.9 0.2 11.4 0.2 1.9 1 1 1 2 2 2 0 FANCI solenoid 3 Hormone_2 PF00123.20 CBY41520.1 - 0.056 13.4 0.3 0.093 12.6 0.3 1.3 1 0 0 1 1 1 0 Peptide hormone An_peroxidase PF03098.15 CBY41521.1 - 1.7e-28 99.5 0.0 2.3e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase DUF2555 PF10742.9 CBY41521.1 - 0.13 12.1 0.1 0.97 9.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2555) CD52 PF15116.6 CBY41522.1 - 0.014 15.4 0.2 0.027 14.5 0.2 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen Kelch_2 PF07646.15 CBY41523.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 CBY41523.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif EGF PF00008.27 CBY41525.1 - 1.1e-06 28.8 3.7 1.1e-06 28.8 3.7 2.0 1 1 1 2 2 2 1 EGF-like domain ETX_MTX2 PF03318.13 CBY41525.1 - 0.0002 21.2 0.0 0.0002 21.2 0.0 3.1 2 1 1 3 3 3 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 EzrA PF06160.12 CBY41525.1 - 0.0032 15.7 1.5 0.0043 15.3 1.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA EGF_2 PF07974.13 CBY41525.1 - 0.0056 17.0 9.1 0.013 15.8 9.1 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 CBY41525.1 - 0.19 12.4 3.9 0.22 12.2 2.2 2.1 1 1 0 1 1 1 0 Human growth factor-like EGF TPR_MLP1_2 PF07926.12 CBY41525.1 - 2.2 8.4 13.3 0.059 13.4 1.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Scramblase PF03803.15 CBY41526.1 - 1.4e-18 67.0 0.0 2.4e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase T4_deiodinase PF00837.17 CBY41529.1 - 9.3e-29 100.4 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase zf-C4H2 PF10146.9 CBY41530.1 - 0.03 14.6 2.4 3.6 7.8 2.5 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein SWI-SNF_Ssr4 PF08549.10 CBY41530.1 - 1.2 7.7 7.5 1.3 7.6 7.5 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) QVR PF17064.5 CBY41530.1 - 7.4 6.9 19.8 0.24 11.6 8.3 3.4 2 2 1 3 3 3 0 Sleepless protein FtsH_ext PF06480.15 CBY41530.1 - 7.5 7.0 11.1 5.1 7.5 6.9 2.5 2 1 0 2 2 2 0 FtsH Extracellular DHHC PF01529.20 CBY41531.1 - 1.1e-27 96.8 8.3 1.1e-27 96.8 8.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase V-SNARE_C PF12352.8 CBY41532.1 - 1.1e-15 57.6 2.6 3e-14 53.0 1.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus MAD PF05557.13 CBY41532.1 - 0.0028 16.1 2.4 0.0032 15.9 2.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Sec20 PF03908.13 CBY41532.1 - 0.024 14.5 0.2 0.068 13.1 0.1 1.7 1 1 0 1 1 1 0 Sec20 Ribosomal_L7Ae PF01248.26 CBY41533.1 - 6.4e-19 67.5 0.0 9.5e-19 66.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family JHBP PF06585.11 CBY41533.1 - 0.071 12.3 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF1977 PF09320.11 CBY41534.1 - 6e-09 36.1 0.4 6e-09 36.1 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) Renin_r PF07850.14 CBY41534.1 - 0.024 15.2 0.0 0.047 14.3 0.0 1.5 1 0 0 1 1 1 0 Renin receptor-like protein Kazal_1 PF00050.21 CBY41535.1 - 3.1e-18 65.5 6.9 1.8e-12 47.1 2.7 2.2 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY41535.1 - 8.2e-12 45.1 11.4 6.5e-10 39.0 3.0 2.4 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Asp_Arg_Hydrox PF05118.15 CBY41538.1 - 1.1e-53 181.3 0.6 2.1e-53 180.4 0.6 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase TPR_2 PF07719.17 CBY41538.1 - 2.8e-09 36.4 0.0 0.066 13.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY41538.1 - 3.4e-06 26.6 0.0 0.057 13.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY41538.1 - 0.00057 20.5 0.6 0.9 10.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41538.1 - 0.0034 17.7 0.0 8.8 6.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY41538.1 - 0.0051 16.7 3.5 11 6.1 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY41538.1 - 0.0069 17.0 0.3 8.1 7.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY41538.1 - 0.007 16.7 0.0 0.062 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41538.1 - 0.012 15.8 0.0 8.9 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0253 PF06786.12 CBY41538.1 - 0.025 14.8 1.6 0.05 13.9 1.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) TPR_6 PF13174.6 CBY41538.1 - 0.032 14.9 0.2 64 4.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Endosulfine PF04667.17 CBY41539.1 - 2.6e-10 40.3 0.9 4.4e-10 39.6 0.9 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Claudin_2 PF13903.6 CBY41540.1 - 0.031 14.0 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ProRS-C_1 PF09180.11 CBY41540.1 - 0.037 14.2 0.1 0.048 13.9 0.1 1.2 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal DUF1835 PF08874.10 CBY41540.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Calici_PP_N PF08405.11 CBY41540.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Viral polyprotein N-terminal Sulfatase PF00884.23 CBY41541.1 - 1.4e-50 172.4 0.5 1.8e-50 172.1 0.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBY41541.1 - 1.6e-06 27.9 2.1 4.1e-06 26.6 2.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY41541.1 - 0.0033 16.1 5.0 0.15 10.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF229) Torus PF16131.5 CBY41542.1 - 3.2e-05 24.6 3.1 3.3e-05 24.5 0.2 2.4 2 1 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 CBY41542.1 - 0.00028 20.8 7.6 0.00028 20.8 7.6 1.6 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBY41542.1 - 0.00077 19.2 3.3 0.0012 18.5 3.3 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CBY41542.1 - 0.003 17.8 0.2 0.0073 16.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Rubis-subs-bind PF09273.11 CBY41542.1 - 0.036 14.8 0.2 0.074 13.7 0.2 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding zf-CCCH PF00642.24 CBY41542.1 - 0.043 13.8 2.9 0.07 13.1 2.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBY41542.1 - 0.14 12.7 2.9 0.22 12.0 2.9 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SGL PF08450.12 CBY41543.1 - 1.3e-34 119.9 0.3 1.6e-34 119.6 0.3 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CBY41543.1 - 0.00014 21.9 0.0 0.047 13.8 0.0 3.4 3 1 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 CBY41543.1 - 0.0011 18.9 5.3 1.5 9.0 0.0 4.7 5 0 0 5 5 5 2 NHL repeat Kelch_6 PF13964.6 CBY41543.1 - 0.024 14.9 0.8 18 5.8 0.1 3.9 3 0 0 3 3 3 0 Kelch motif SBBP PF06739.11 CBY41543.1 - 0.072 13.1 0.7 5 7.2 0.5 2.7 2 0 0 2 2 2 0 Beta-propeller repeat Reg_prop PF07494.11 CBY41543.1 - 0.075 13.3 0.1 6.9 7.3 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller Kelch_1 PF01344.25 CBY41543.1 - 0.12 12.0 0.7 15 5.3 0.2 3.4 3 0 0 3 3 3 0 Kelch motif SMG1_N PF17229.2 CBY41543.1 - 0.13 12.9 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal G_glu_transpept PF01019.21 CBY41544.1 - 2e-129 432.7 0.0 1.4e-128 429.9 0.0 1.8 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 CBY41547.1 - 4.6e-40 137.7 0.0 5.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41547.1 - 1.2e-20 73.9 0.0 3.9e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBY41547.1 - 0.0033 16.5 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 CBY41547.1 - 0.035 13.4 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DDHD PF02862.17 CBY41548.1 - 0.71 10.0 12.3 4.9 7.3 0.5 2.3 2 0 0 2 2 2 0 DDHD domain BAF1_ABF1 PF04684.13 CBY41548.1 - 1.1 8.3 27.9 0.7 8.9 12.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.7 CBY41548.1 - 2.8 5.9 23.1 2.6 6.1 10.7 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CDK2AP PF09806.9 CBY41549.1 - 0.013 15.6 2.3 0.021 14.9 2.3 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein LuxE PF04443.12 CBY41549.1 - 0.018 14.1 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE Levi_coat PF01819.17 CBY41549.1 - 0.093 12.7 0.3 0.57 10.2 0.6 2.0 2 0 0 2 2 2 0 Levivirus coat protein LicD PF04991.13 CBY41549.1 - 0.35 11.0 7.0 0.42 10.7 7.0 1.1 1 0 0 1 1 1 0 LicD family VASt PF16016.5 CBY41550.1 - 9.2e-19 68.4 0.2 1.3e-18 67.9 0.2 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF3641 PF12345.8 CBY41550.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) C1q PF00386.21 CBY41551.1 - 3.8e-14 53.0 0.0 7.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 C1q domain BclA_C PF18573.1 CBY41551.1 - 0.077 12.9 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 BclA C-terminal domain Hydrolase_6 PF13344.6 CBY41552.1 - 1.6e-18 66.7 0.0 5e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBY41552.1 - 5.7e-05 23.1 0.0 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CBY41552.1 - 0.16 12.2 0.0 7.6 6.8 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase EF1_GNE PF00736.19 CBY41553.1 - 5.7e-34 116.2 1.0 1.4e-33 114.9 1.0 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CBY41553.1 - 3e-14 53.2 5.3 3e-14 53.2 5.3 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Cnn_1N PF07989.11 CBY41553.1 - 0.01 16.0 0.6 0.035 14.3 0.0 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cwf_Cwc_15 PF04889.12 CBY41553.1 - 0.032 14.0 5.2 0.037 13.8 5.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOP5NT PF08156.13 CBY41553.1 - 0.08 13.3 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 NOP5NT (NUC127) domain CASP_C PF08172.12 CBY41553.1 - 0.2 10.9 1.3 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 CASP C terminal CDO_I PF05995.12 CBY41555.1 - 0.092 12.1 0.2 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Cysteine dioxygenase type I CLAMP PF14769.6 CBY41556.1 - 0.087 13.3 0.7 16 6.0 0.1 2.7 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 vATP-synt_E PF01991.18 CBY41557.1 - 2.6e-33 115.1 0.9 3.1e-33 114.9 0.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Str_synth PF03088.16 CBY41557.1 - 0.022 14.9 0.1 0.042 14.0 0.1 1.5 1 0 0 1 1 1 0 Strictosidine synthase PRAI PF00697.22 CBY41557.1 - 0.096 12.4 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Polysacc_synt_4 PF04669.13 CBY41558.1 - 2.7e-17 63.0 0.1 1.3e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis UCMA PF17085.5 CBY41558.1 - 0.0078 16.2 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Unique cartilage matrix associated protein Polysacc_synt_4 PF04669.13 CBY41560.1 - 2.5e-10 40.2 0.1 0.00042 19.9 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis Rx_N PF18052.1 CBY41560.1 - 0.033 14.4 0.5 0.077 13.3 0.1 1.8 2 0 0 2 2 2 0 Rx N-terminal domain HNH_5 PF14279.6 CBY41561.1 - 0.024 14.5 0.6 0.078 12.8 0.6 2.0 1 1 0 1 1 1 0 HNH endonuclease Thyroglobulin_1 PF00086.18 CBY41562.1 - 7.6e-09 35.1 0.9 1.7e-08 34.0 0.9 1.5 1 0 0 1 1 1 1 Thyroglobulin type-1 repeat Sulfatase PF00884.23 CBY41563.1 - 1.8e-24 86.7 0.4 7.7e-24 84.6 0.4 1.8 1 1 0 1 1 1 1 Sulfatase AvrB_AvrC PF05394.11 CBY41563.1 - 0.0093 15.2 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 1 Avirulence protein SH3_1 PF00018.28 CBY41564.1 - 0.0014 18.2 0.0 0.047 13.3 0.1 2.1 2 0 0 2 2 2 2 SH3 domain VWA PF00092.28 CBY41567.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 CBY41567.1 - 0.17 12.5 0.0 0.48 11.1 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain NID PF07292.13 CBY41568.1 - 0.1 13.3 0.0 0.1 13.3 0.0 1.0 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) Mucin2_WxxW PF13330.6 CBY41570.1 - 2.5e-40 137.2 0.5 6.9e-18 65.3 0.0 3.8 4 0 0 4 4 4 2 Mucin-2 protein WxxW repeating region Piezo_RRas_bdg PF12166.8 CBY41571.1 - 1.5e-71 241.9 0.1 1.8e-71 241.7 0.1 1.1 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain DUF5082 PF16888.5 CBY41573.1 - 0.0076 16.5 7.0 0.17 12.2 2.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) SH3BP5 PF05276.14 CBY41573.1 - 0.0081 16.0 4.0 0.01 15.7 4.0 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Phage_TAC_7 PF10109.9 CBY41573.1 - 0.076 13.1 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 TMPIT PF07851.13 CBY41573.1 - 0.4 9.9 6.9 0.43 9.8 6.9 1.0 1 0 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 CBY41573.1 - 1.9 8.6 8.6 2.3 8.4 8.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Adaptin_N PF01602.20 CBY41574.1 - 8.1e-65 219.4 0.4 9.6e-65 219.1 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBY41574.1 - 7.5e-08 32.6 0.3 0.0078 16.3 0.2 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Trypan_PARP PF05887.11 CBY41574.1 - 0.24 11.4 4.6 0.39 10.7 4.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pns11_12 PF17464.2 CBY41574.1 - 2 8.1 12.7 3.7 7.2 12.7 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Presenilin PF01080.17 CBY41574.1 - 5 5.8 8.0 7.3 5.2 8.0 1.1 1 0 0 1 1 1 0 Presenilin Urocanase_C PF17392.2 CBY41577.1 - 6.4e-71 237.9 2.1 7.6e-71 237.6 2.1 1.0 1 0 0 1 1 1 1 Urocanase C-terminal domain TPH PF13868.6 CBY41580.1 - 1.7e-45 155.1 89.6 2.1e-45 154.7 89.6 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain CoA_binding_3 PF13727.6 CBY41580.1 - 0.17 11.9 0.8 0.34 10.9 0.8 1.5 1 0 0 1 1 1 0 CoA-binding domain EFF-AFF PF14884.6 CBY41580.1 - 0.18 9.9 2.5 0.29 9.2 2.5 1.4 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen RRM_1 PF00076.22 CBY41581.1 - 5.8e-83 272.7 2.8 1.5e-20 72.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBY41581.1 - 5.5e-26 90.5 0.2 1.3e-25 89.3 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBY41581.1 - 2.4e-09 36.9 0.0 0.009 15.9 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CBY41581.1 - 1.3e-06 28.0 0.1 0.56 9.8 0.0 3.5 2 2 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY41581.1 - 2.6e-06 27.3 0.1 0.022 14.8 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBY41581.1 - 3.9e-05 23.7 1.0 4.2 7.6 0.1 4.9 4 3 0 4 4 4 2 RNA recognition motif Limkain-b1 PF11608.8 CBY41581.1 - 0.00062 19.8 1.0 3.3 7.8 0.0 4.4 4 1 0 4 4 4 1 Limkain b1 YflT PF11181.8 CBY41581.1 - 0.014 15.9 0.7 3.9 8.0 0.3 3.4 4 0 0 4 4 4 0 Heat induced stress protein YflT SET_assoc PF11767.8 CBY41581.1 - 0.061 13.0 1.3 22 4.8 0.0 3.6 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RNA_bind PF08675.11 CBY41581.1 - 0.095 12.7 0.1 4.3 7.4 0.0 3.6 5 0 0 5 5 5 0 RNA binding domain TPR_2 PF07719.17 CBY41582.1 - 8.8e-07 28.6 0.3 0.032 14.4 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBY41582.1 - 1.7e-05 24.5 1.9 0.013 15.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41582.1 - 1.7e-05 24.7 1.7 0.7 10.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBY41582.1 - 0.0001 21.9 0.8 0.39 10.4 0.0 3.6 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 CBY41582.1 - 0.00022 21.8 0.0 10 6.8 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBY41582.1 - 0.00039 20.2 0.2 0.78 9.9 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41582.1 - 0.0015 18.8 0.7 0.58 10.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 CBY41582.1 - 0.0018 18.3 1.0 0.38 10.8 0.3 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY41582.1 - 0.0028 17.9 0.1 2.3 8.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY41582.1 - 0.011 15.9 0.1 4.3 7.6 0.1 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBY41582.1 - 0.015 15.9 0.1 49 4.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 CBY41582.1 - 0.019 15.0 0.2 0.36 10.9 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 CBY41582.1 - 0.031 14.0 0.1 0.43 10.3 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain YfdX PF10938.8 CBY41582.1 - 0.079 12.9 1.2 5.5 6.9 0.2 3.6 4 1 0 4 4 4 0 YfdX protein TAL_FSA PF00923.19 CBY41584.1 - 9.8e-41 140.0 0.0 1.1e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase dsrm PF00035.26 CBY41585.1 - 1.7e-08 35.1 0.0 3.2e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif Shugoshin_N PF07558.11 CBY41585.1 - 0.044 13.7 0.3 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region dsrm PF00035.26 CBY41586.1 - 0.03 15.0 0.1 0.77 10.5 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif zf-C2H2_2 PF12756.7 CBY41587.1 - 1.3e-09 38.3 13.5 1 9.7 0.5 6.0 2 1 2 6 6 6 4 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 CBY41587.1 - 2.4e-08 34.4 10.4 0.0065 16.7 0.0 5.1 4 1 0 5 5 5 2 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.7 CBY41587.1 - 2.4e-07 30.9 29.9 0.0012 19.2 0.4 6.9 7 1 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CBY41587.1 - 1.2e-06 28.7 35.6 0.00036 20.8 0.4 7.5 8 0 0 8 8 8 2 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CBY41587.1 - 1.8e-06 27.5 9.9 0.034 13.8 0.1 5.3 5 0 0 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 CBY41587.1 - 3e-06 26.9 1.1 0.00015 21.4 0.7 5.4 6 0 0 6 6 6 2 C2H2-type zinc-finger domain CpXC PF14353.6 CBY41587.1 - 0.0011 18.9 10.4 2.3 8.3 0.0 4.5 3 2 0 4 4 4 1 CpXC protein zf-C2H2_4 PF13894.6 CBY41587.1 - 0.0013 19.4 24.4 1.4 10.0 0.1 7.4 7 0 0 7 7 7 1 C2H2-type zinc finger zf-C2H2_12 PF18658.1 CBY41587.1 - 0.011 15.3 10.1 0.092 12.3 0.1 4.7 5 0 0 5 5 5 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CBY41587.1 - 0.013 16.0 22.3 0.72 10.4 1.4 6.6 7 0 0 7 7 7 0 Zinc-finger double domain Actin_micro PF17003.5 CBY41587.1 - 0.023 13.9 8.9 1.6 7.8 5.2 3.7 1 1 1 2 2 2 0 Putative actin-like family Vps36-NZF-N PF16988.5 CBY41587.1 - 0.031 13.7 20.0 2.2 7.7 1.0 5.8 6 1 0 6 6 6 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-UBP PF02148.19 CBY41587.1 - 0.043 14.2 15.1 0.058 13.7 1.0 4.3 3 2 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.7 CBY41587.1 - 0.066 13.3 14.2 0.69 10.0 0.3 4.7 4 1 0 4 4 4 0 Double zinc ribbon DUF3449 PF11931.8 CBY41587.1 - 0.16 11.7 6.8 0.41 10.4 0.0 3.7 2 1 1 4 4 4 0 Domain of unknown function (DUF3449) Rubredoxin_2 PF18073.1 CBY41587.1 - 0.43 10.4 22.9 2.2 8.0 0.9 5.6 5 0 0 5 5 5 0 Rubredoxin metal binding domain OrfB_Zn_ribbon PF07282.11 CBY41587.1 - 0.45 10.5 8.2 18 5.3 0.1 4.7 5 0 0 5 5 5 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 CBY41587.1 - 0.94 9.4 6.5 24 4.9 0.1 4.4 4 0 0 4 4 4 0 Halobacterial output domain 2 Rubredoxin PF00301.20 CBY41587.1 - 1.1 9.4 16.5 22 5.2 0.0 5.6 6 0 0 6 6 6 0 Rubredoxin DUF2225 PF09986.9 CBY41587.1 - 2.2 7.9 9.5 2.4 7.8 0.1 3.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF202 PF02656.15 CBY41589.1 - 0.042 14.3 1.4 0.59 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Trypsin PF00089.26 CBY41591.1 - 1.4e-08 34.9 1.4 2.8e-07 30.6 1.4 2.4 1 1 0 1 1 1 1 Trypsin DUF1986 PF09342.11 CBY41591.1 - 0.083 13.3 0.3 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) Tau95 PF09734.9 CBY41594.1 - 3.6 8.4 6.1 0.47 11.2 0.1 2.5 3 1 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain LRR_9 PF14580.6 CBY41595.1 - 1.5e-12 47.4 2.3 2.3e-12 46.8 2.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBY41595.1 - 3.5e-10 40.0 9.6 1.5e-05 25.3 1.0 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY41595.1 - 1.5e-08 34.2 1.3 1.5e-08 34.2 1.3 3.0 3 1 0 3 3 3 1 Leucine rich repeat LRR_2 PF07723.13 CBY41595.1 - 0.43 11.3 1.3 30 5.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBY41595.1 - 1.3 9.2 7.7 49 4.4 0.4 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBY41595.1 - 1.7 9.5 10.1 1.2e+02 3.8 0.1 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat C8 PF08742.11 CBY41596.1 - 0.00018 21.9 3.0 0.00018 21.9 3.0 3.3 2 2 1 3 3 3 1 C8 domain zf-TRAF PF02176.18 CBY41597.1 - 0.00027 21.6 5.5 0.00027 21.6 5.5 1.8 1 1 1 2 2 2 1 TRAF-type zinc finger Sina PF03145.16 CBY41597.1 - 0.0016 18.4 6.4 0.0022 18.0 5.8 1.3 1 1 0 1 1 1 1 Seven in absentia protein family Plectin PF00681.20 CBY41598.1 - 4.8e-53 176.8 2.1 1e-09 38.1 0.0 10.0 7 3 3 10 10 10 7 Plectin repeat EphA2_TM PF14575.6 CBY41598.1 - 0.097 13.6 0.1 74 4.3 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ge1_WD40 PF16529.5 CBY41599.1 - 1.3e-77 261.0 0.3 2.2e-77 260.2 0.3 1.2 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CBY41599.1 - 4.3e-08 33.7 2.0 8.3e-06 26.4 0.2 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.6 CBY41599.1 - 0.00094 19.6 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CBY41599.1 - 0.0078 16.2 0.2 0.019 14.9 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Subtilosin_A PF11420.8 CBY41599.1 - 0.037 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriocin subtilosin A Phage_HK97_TLTM PF06120.11 CBY41599.1 - 0.057 12.6 3.0 0.2 10.8 3.0 2.0 1 0 0 1 1 1 0 Tail length tape measure protein Prominin PF05478.11 CBY41599.1 - 0.96 7.3 7.8 0.34 8.8 2.6 2.1 2 0 0 2 2 2 0 Prominin DCB PF16213.5 CBY41599.1 - 1.2 8.7 4.9 12 5.5 1.4 3.0 2 1 1 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 Lebercilin PF15619.6 CBY41599.1 - 3.4 7.3 12.8 0.067 12.8 4.2 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2884 PF11101.8 CBY41599.1 - 9 5.7 10.6 0.59 9.6 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) UTP15_C PF09384.10 CBY41601.1 - 4.6e-29 101.0 1.3 8.1e-29 100.2 1.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CBY41601.1 - 4.8e-18 65.2 6.7 8.9e-05 23.2 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY41601.1 - 7.3e-09 35.8 0.3 0.14 12.4 0.0 5.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBY41601.1 - 0.033 13.2 0.3 0.9 8.4 0.1 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY41601.1 - 0.065 11.8 0.1 5.1 5.5 0.0 2.5 1 1 2 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 CBY41601.1 - 0.81 10.3 3.4 52 4.5 0.0 3.9 4 1 0 4 4 4 0 PQQ-like domain Kinesin PF00225.23 CBY41602.1 - 6.2e-100 334.4 0.1 1.1e-99 333.5 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBY41602.1 - 4e-25 88.5 2.9 5.7e-25 88.0 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding Filament PF00038.21 CBY41602.1 - 0.0052 16.4 16.5 0.012 15.2 16.5 1.6 1 0 0 1 1 1 1 Intermediate filament protein UPF0176_N PF17773.1 CBY41602.1 - 0.068 13.5 0.2 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 UPF0176 acylphosphatase like domain bZIP_2 PF07716.15 CBY41602.1 - 0.12 12.5 17.7 0.075 13.1 3.6 3.8 4 0 0 4 4 4 0 Basic region leucine zipper bZIP_1 PF00170.21 CBY41602.1 - 0.15 12.2 17.3 0.29 11.3 2.5 3.6 3 0 0 3 3 3 0 bZIP transcription factor Cnn_1N PF07989.11 CBY41602.1 - 0.46 10.7 19.2 0.029 14.5 9.5 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 CBY41602.1 - 5.1 8.0 23.9 3.7 8.5 10.5 3.8 3 2 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Death PF00531.22 CBY41602.1 - 5.2 7.3 10.4 4.6 7.5 0.2 4.3 4 1 1 5 5 5 0 Death domain SlyX PF04102.12 CBY41602.1 - 5.4 7.7 7.8 14 6.4 0.1 3.9 1 1 1 3 3 3 0 SlyX HALZ PF02183.18 CBY41602.1 - 9.5 6.5 12.7 26 5.1 3.2 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Pkinase PF00069.25 CBY41604.1 - 9.2e-40 136.7 0.0 1.2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41604.1 - 1.9e-16 60.2 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY41604.1 - 2.3e-10 40.2 0.0 4.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY41604.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY41604.1 - 0.0006 18.9 0.0 0.0008 18.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY41604.1 - 0.00071 19.6 0.0 0.00099 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY41604.1 - 0.0041 16.5 0.0 0.0099 15.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 CBY41604.1 - 0.0067 16.0 0.3 0.014 15.0 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Y_phosphatase PF00102.27 CBY41606.1 - 2.4e-63 213.8 0.1 3.4e-63 213.3 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBY41606.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family zf-C2H2 PF00096.26 CBY41608.1 - 6.6e-12 45.2 20.1 0.00028 21.1 2.6 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY41608.1 - 2.2e-11 43.7 8.6 0.00017 21.8 0.1 4.2 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY41608.1 - 1.9e-10 40.7 14.8 0.0025 18.5 1.3 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 CBY41608.1 - 4.8e-08 33.1 9.3 0.0081 16.5 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CBY41608.1 - 3.1e-05 23.9 18.0 0.0044 17.0 1.3 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY41608.1 - 4.1e-05 23.8 29.7 0.021 15.2 6.4 4.7 4 1 1 5 5 5 3 Zinc-finger double domain YyzF PF14116.6 CBY41608.1 - 0.065 13.3 3.0 0.43 10.6 0.7 2.4 2 0 0 2 2 2 0 YyzF-like protein zf-C2H2_2 PF12756.7 CBY41608.1 - 0.11 12.8 11.0 3.2 8.2 11.0 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CBY41608.1 - 0.15 11.9 4.7 0.56 10.0 0.3 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type PyrI_C PF02748.15 CBY41608.1 - 0.25 11.3 5.6 0.22 11.5 1.8 2.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CBY41608.1 - 0.25 11.4 15.4 3.1 7.9 0.2 3.4 2 1 1 3 3 3 0 BED zinc finger Mito_carr PF00153.27 CBY41610.1 - 1.1e-13 50.9 2.7 4.8e-12 45.6 0.5 2.7 1 1 1 2 2 2 2 Mitochondrial carrier protein SMP_LBD PF17047.5 CBY41611.1 - 4e-20 72.0 0.1 5e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 CBY41611.1 - 0.0097 15.0 0.7 0.022 13.8 0.7 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 NDK PF00334.19 CBY41612.1 - 2e-70 235.0 0.1 4.9e-32 110.8 0.0 3.3 2 1 1 3 3 3 3 Nucleoside diphosphate kinase Thioredoxin PF00085.20 CBY41612.1 - 6.1e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Arg_repressor PF01316.21 CBY41612.1 - 0.005 16.6 0.8 1.2 8.9 0.0 3.5 3 0 0 3 3 3 1 Arginine repressor, DNA binding domain IlvN PF07991.12 CBY41612.1 - 0.016 14.8 0.4 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1987 PF09345.10 CBY41613.1 - 1.7 8.3 6.2 12 5.6 0.0 4.5 4 1 2 6 6 6 0 Domain of unknown function (DUF1987) TUSC2 PF15000.6 CBY41614.1 - 6.6e-07 29.6 0.0 8.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Tumour suppressor candidate 2 TPD PF14811.6 CBY41615.1 - 2.8e-48 163.2 0.1 4.8e-48 162.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Transketolase_N PF00456.21 CBY41616.1 - 3e-25 88.9 0.1 3.6e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CBY41617.1 - 7.7e-35 120.2 0.0 1.3e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY41617.1 - 2.7e-30 104.8 0.9 5.8e-30 103.7 0.9 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 CBY41617.1 - 2.2e-13 49.9 0.3 4.8e-13 48.8 0.1 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 CBY41617.1 - 0.0017 17.4 0.1 0.0033 16.4 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component PFOR_II PF17147.4 CBY41617.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II NDK PF00334.19 CBY41619.1 - 1.3e-12 47.8 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase zf-C2H2 PF00096.26 CBY41621.1 - 5.1e-13 48.7 16.2 0.00028 21.2 4.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBY41621.1 - 2.7e-11 43.5 5.2 0.00026 21.2 0.1 3.6 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBY41621.1 - 9.9e-11 41.5 12.3 0.0018 18.9 2.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY41621.1 - 5.9e-08 32.8 9.5 0.013 15.9 0.3 3.4 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY41621.1 - 0.00016 21.9 23.0 0.069 13.6 0.2 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBY41621.1 - 0.0002 21.3 14.7 0.071 13.1 2.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY41621.1 - 0.0098 15.6 4.7 0.95 9.3 0.4 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-BED PF02892.15 CBY41621.1 - 0.04 14.0 10.5 4.9 7.3 0.2 3.0 1 1 1 2 2 2 0 BED zinc finger ADK_lid PF05191.14 CBY41621.1 - 0.07 13.1 4.9 3.6 7.6 0.2 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 CBY41621.1 - 0.2 12.0 8.8 6.4 7.2 8.9 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 CBY41621.1 - 4.2 7.6 9.1 29 4.9 9.1 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 CBY41621.1 - 6.3 6.8 11.2 3.7 7.5 0.2 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PAC4 PF16093.5 CBY41623.1 - 0.066 13.4 0.4 0.066 13.4 0.4 1.7 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Sulfotransfer_1 PF00685.27 CBY41624.1 - 3.2e-11 43.2 2.9 5.3e-11 42.5 0.5 2.4 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY41624.1 - 1.8e-07 31.8 1.9 1.8e-06 28.5 1.9 2.5 1 1 0 1 1 1 1 Sulfotransferase family Phospholamban PF04272.14 CBY41624.1 - 0.035 13.6 3.4 0.18 11.3 0.2 2.4 2 0 0 2 2 2 0 Phospholamban Wzy_C PF04932.15 CBY41624.1 - 0.16 11.6 1.0 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 O-Antigen ligase LRR_5 PF13306.6 CBY41625.1 - 1.9e-08 34.3 2.3 3.2e-08 33.6 0.2 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_8 PF13855.6 CBY41625.1 - 1.8e-05 24.4 0.1 0.0013 18.4 0.0 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRRNT PF01462.18 CBY41625.1 - 0.024 14.3 2.4 0.024 14.3 2.4 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain zf-CCCH PF00642.24 CBY41626.1 - 1.1e-17 63.4 11.9 3.8e-10 39.4 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY41626.1 - 6.2e-08 32.3 9.9 4.1e-05 23.3 2.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY41626.1 - 1.7e-07 31.1 13.4 2.7e-05 24.1 4.0 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CBY41626.1 - 0.026 15.2 8.1 0.13 13.0 0.9 2.3 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 CBY41626.1 - 0.49 11.0 3.0 19 5.9 0.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_2 PF14608.6 CBY41626.1 - 0.56 10.8 10.9 3.6 8.2 1.0 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF5595 PF18077.1 CBY41628.1 - 0.0008 19.4 3.4 0.023 14.8 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5595) Miff PF05644.11 CBY41628.1 - 0.0046 16.6 0.4 0.007 16.0 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff ATG16 PF08614.11 CBY41628.1 - 0.0053 17.0 3.2 0.0053 17.0 3.2 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Cnn_1N PF07989.11 CBY41628.1 - 0.014 15.6 5.6 0.014 15.6 5.6 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF4763 PF15960.5 CBY41628.1 - 0.018 14.4 8.8 0.57 9.4 3.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) ADIP PF11559.8 CBY41628.1 - 0.041 14.0 2.1 0.041 14.0 2.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 CBY41628.1 - 0.087 13.3 4.7 0.14 12.6 4.7 1.2 1 0 0 1 1 1 0 Fez1 KLRAQ PF10205.9 CBY41628.1 - 0.099 12.9 9.0 0.047 13.9 2.9 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein FapA PF03961.13 CBY41628.1 - 0.12 11.0 3.5 0.21 10.2 3.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 CBY41628.1 - 0.17 11.8 7.3 0.061 13.2 2.4 2.5 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CBY41628.1 - 0.5 9.7 5.7 0.73 9.1 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CBY41628.1 - 1.2 8.5 10.3 0.11 11.9 5.4 1.8 2 0 0 2 2 2 0 FAM76 protein Lipoprotein_20 PF13942.6 CBY41628.1 - 1.3 8.9 10.3 3.5 7.5 5.6 2.4 1 1 2 3 3 3 0 YfhG lipoprotein SlyX PF04102.12 CBY41628.1 - 6.5 7.4 7.9 4.7 7.9 2.5 2.6 1 1 1 2 2 2 0 SlyX Peptidase_S9 PF00326.21 CBY41630.1 - 3.1e-10 39.9 0.1 3.3e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBY41630.1 - 0.043 13.6 0.1 0.051 13.4 0.1 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Kelch_6 PF13964.6 CBY41631.1 - 0.00012 22.2 8.4 21 5.6 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CBY41631.1 - 8.1 6.6 18.2 22 5.2 0.2 5.9 6 1 0 6 6 6 0 Kelch motif SH3_1 PF00018.28 CBY41634.1 - 3.3e-15 55.4 2.0 5.4e-08 32.3 0.9 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CBY41634.1 - 7.7e-10 38.5 0.1 0.0004 20.2 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CBY41634.1 - 5.6e-09 35.6 0.1 0.00015 21.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CBY41634.1 - 0.00045 20.5 1.1 0.052 13.8 0.2 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain NBP1 PF08537.10 CBY41634.1 - 0.0019 17.7 0.6 0.0033 16.9 0.6 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 SH3_16 PF18348.1 CBY41634.1 - 0.0041 16.9 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain Imm61 PF15598.6 CBY41634.1 - 0.021 14.7 0.7 0.41 10.5 0.1 2.4 1 1 2 3 3 3 0 Immunity protein 61 TSP_1 PF00090.19 CBY41635.1 - 1.1e-19 70.3 61.8 1.5e-07 31.5 13.6 4.4 4 0 0 4 4 4 4 Thrombospondin type 1 domain Phage_connect_1 PF05135.13 CBY41635.1 - 0.0088 16.5 0.7 0.016 15.7 0.7 1.4 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein Coilin_N PF15862.5 CBY41637.1 - 0.0014 18.4 0.7 0.0014 18.4 0.7 4.3 4 1 0 4 4 4 1 Coilin N-terminus ADK PF00406.22 CBY41637.1 - 0.0024 18.0 0.1 0.0079 16.3 0.1 1.9 1 0 0 1 1 1 1 Adenylate kinase DUF5619 PF18505.1 CBY41637.1 - 0.052 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) UME PF08064.13 CBY41637.1 - 0.53 10.2 2.0 1.8 8.5 0.3 2.4 2 0 0 2 2 2 0 UME (NUC010) domain DUF4404 PF14357.6 CBY41637.1 - 6.1 7.6 14.2 4.6 8.0 1.6 4.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Ist1 PF03398.14 CBY41638.1 - 9.9e-27 93.9 0.1 1.1e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RQC PF09382.10 CBY41638.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 RQC domain Galactosyl_T PF01762.21 CBY41640.1 - 5.8e-16 58.9 0.0 1.4e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase DUF3591 PF12157.8 CBY41641.1 - 1.2e-97 327.4 0.0 1.2e-97 327.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 CBY41641.1 - 5.8e-40 135.2 3.6 2.4e-19 69.2 0.3 2.7 2 0 0 2 2 2 2 Bromodomain BCA_ABC_TP_C PF12399.8 CBY41641.1 - 1.6 8.7 3.2 7.6 6.6 0.3 2.8 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter HisKA_3 PF07730.13 CBY41641.1 - 2.2 8.9 5.8 16 6.1 0.1 2.8 2 0 0 2 2 2 0 Histidine kinase Sec20 PF03908.13 CBY41641.1 - 3.2 7.7 5.5 11 6.0 0.1 3.5 3 0 0 3 3 3 0 Sec20 PCMT PF01135.19 CBY41642.1 - 1.1e-54 185.4 0.0 1.3e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CBY41642.1 - 5.6e-06 27.0 0.0 1.2e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY41642.1 - 5.1e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY41642.1 - 0.0012 18.7 0.4 0.0027 17.5 0.2 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY41642.1 - 0.0016 19.0 0.0 0.0038 17.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBY41642.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBY41642.1 - 0.0043 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 CBY41642.1 - 0.061 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 CBY41642.1 - 0.064 12.8 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CBY41642.1 - 0.18 11.2 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CaMKII_AD PF08332.10 CBY41643.1 - 4.2e-37 127.2 0.0 6.4e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Pkinase PF00069.25 CBY41643.1 - 1.2e-29 103.4 0.0 4.5e-29 101.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41643.1 - 4.4e-08 32.7 0.0 8.6e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Mltc_N PF11873.8 CBY41643.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Membrane-bound lytic murein transglycosylase C, N-terminal domain SnoaL_3 PF13474.6 CBY41643.1 - 0.038 14.3 0.0 0.085 13.1 0.0 1.6 1 1 0 1 1 1 0 SnoaL-like domain Sulfotransfer_2 PF03567.14 CBY41644.1 - 1.2e-41 143.3 0.8 1.8e-41 142.7 0.8 1.2 1 0 0 1 1 1 1 Sulfotransferase family RPM2 PF08579.11 CBY41644.1 - 0.16 12.4 0.4 0.36 11.2 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Guanylate_kin PF00625.21 CBY41645.1 - 3.1e-28 98.7 0.0 1.1e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 Guanylate kinase ImpA_N PF06812.12 CBY41645.1 - 0.16 12.1 0.3 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system zf-RING_2 PF13639.6 CBY41646.1 - 6.1e-06 26.5 3.1 1.1e-05 25.6 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY41646.1 - 4e-05 23.5 1.2 7.2e-05 22.7 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY41646.1 - 5.3e-05 23.1 3.6 9.8e-05 22.2 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY41646.1 - 0.00049 19.9 1.9 0.0012 18.7 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY41646.1 - 0.0012 18.6 3.0 0.0041 16.9 3.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CpG_bind_C PF12269.8 CBY41646.1 - 0.0015 18.3 6.1 0.0015 18.3 6.1 2.0 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain IPK PF03770.16 CBY41646.1 - 0.012 15.5 0.5 0.015 15.1 0.5 1.3 1 0 0 1 1 1 0 Inositol polyphosphate kinase Iron_permease PF04120.12 CBY41646.1 - 0.025 14.3 1.2 0.025 14.3 1.2 1.5 2 0 0 2 2 2 0 Low affinity iron permease zf-RING_11 PF17123.5 CBY41646.1 - 0.034 13.9 2.8 0.07 12.9 2.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger Exonuc_VII_L PF02601.15 CBY41646.1 - 0.095 12.3 3.1 0.13 11.9 3.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C3HC4_3 PF13920.6 CBY41646.1 - 0.11 12.4 2.2 0.24 11.3 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY41646.1 - 0.19 11.9 3.8 0.36 11.0 0.4 2.5 1 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY41646.1 - 0.28 11.5 5.0 0.11 12.8 2.3 1.7 2 0 0 2 2 1 0 RING-H2 zinc finger domain C1_2 PF03107.16 CBY41646.1 - 0.32 11.3 3.8 0.54 10.6 3.8 1.4 1 0 0 1 1 1 0 C1 domain zf-HC5HC2H PF13771.6 CBY41646.1 - 0.36 11.1 7.0 0.71 10.2 6.8 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain Mt_ATP-synt_D PF05873.12 CBY41646.1 - 0.39 10.5 7.1 0.71 9.7 7.1 1.6 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) PHD_4 PF16866.5 CBY41646.1 - 0.54 10.4 6.8 1.2 9.3 6.8 1.6 1 0 0 1 1 1 0 PHD-finger FemAB PF02388.16 CBY41646.1 - 0.56 9.0 5.7 0.074 11.9 1.8 1.4 2 0 0 2 2 2 0 FemAB family V_ATPase_I PF01496.19 CBY41646.1 - 0.77 7.6 6.4 0.91 7.4 6.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Hsk3 PF08227.11 CBY41646.1 - 1.1 9.6 4.6 3.3 8.2 0.2 2.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Kelch_6 PF13964.6 CBY41650.1 - 0.021 15.1 0.2 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 CBY41650.1 - 0.054 13.5 0.1 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 CBY41650.1 - 0.46 10.5 4.0 0.6 10.2 0.6 2.2 2 0 0 2 2 2 0 Kelch motif ABC_membrane PF00664.23 CBY41651.1 - 4e-22 79.2 11.6 3.3e-19 69.6 5.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBY41651.1 - 2.8e-20 73.2 0.0 4.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY41651.1 - 1.6e-06 27.8 0.2 0.0036 16.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Yip1 PF04893.17 CBY41651.1 - 0.0047 16.7 0.4 0.0047 16.7 0.4 2.9 3 0 0 3 3 3 1 Yip1 domain Zeta_toxin PF06414.12 CBY41651.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 CBY41651.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CBY41651.1 - 0.024 14.3 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY41651.1 - 0.051 14.1 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBY41651.1 - 0.055 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBY41651.1 - 0.059 13.5 0.4 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 CBY41651.1 - 0.32 10.8 1.2 1.3 8.8 0.1 2.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system CAP PF00188.26 CBY41653.1 - 1.8e-11 45.0 0.3 4e-11 43.8 0.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family cEGF PF12662.7 CBY41653.1 - 8.5e-06 25.6 25.0 0.00055 19.8 5.2 4.7 4 0 0 4 4 4 2 Complement Clr-like EGF-like CUB PF00431.20 CBY41653.1 - 9.3e-05 22.7 0.0 0.57 10.5 0.0 2.8 2 0 0 2 2 2 2 CUB domain EGF_CA PF07645.15 CBY41653.1 - 0.0017 18.5 37.4 0.011 15.9 2.2 5.7 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.7 CBY41653.1 - 0.0022 18.2 29.3 0.032 14.4 2.3 5.1 4 0 0 4 4 4 3 EGF domain EGF PF00008.27 CBY41653.1 - 9.9 6.6 36.7 0.018 15.3 5.0 5.6 5 0 0 5 5 5 0 EGF-like domain Ion_trans PF00520.31 CBY41654.1 - 0.015 14.5 4.9 0.022 14.0 4.9 1.2 1 0 0 1 1 1 0 Ion transport protein CDK2AP PF09806.9 CBY41654.1 - 0.029 14.4 2.7 0.048 13.7 2.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3413 PF11893.8 CBY41654.1 - 0.074 12.2 6.7 0.06 12.5 4.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) LicD PF04991.13 CBY41654.1 - 0.59 10.2 7.0 0.83 9.8 7.0 1.2 1 0 0 1 1 1 0 LicD family Lung_7-TM_R PF06814.13 CBY41654.1 - 0.82 8.9 7.0 2.7 7.2 7.0 1.6 1 1 0 1 1 1 0 Lung seven transmembrane receptor p450 PF00067.22 CBY41654.1 - 1.6 7.4 7.5 3.9 6.1 0.6 2.0 1 1 1 2 2 2 0 Cytochrome P450 Ninjurin PF04923.12 CBY41654.1 - 2.8 7.9 8.5 0.64 10.0 3.8 2.2 1 1 0 2 2 2 0 Ninjurin VASt PF16016.5 CBY41655.1 - 9.2e-19 68.4 0.2 1.3e-18 67.9 0.2 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF3641 PF12345.8 CBY41655.1 - 0.063 13.3 0.1 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3641) C1q PF00386.21 CBY41656.1 - 5.6e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 C1q domain IL3 PF02059.15 CBY41658.1 - 0.097 12.7 1.7 0.11 12.6 0.4 1.7 2 0 0 2 2 2 0 Interleukin-3 Nramp PF01566.18 CBY41659.1 - 9.7e-114 380.1 10.3 9.7e-114 380.1 10.3 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phospholip_A2_1 PF00068.19 CBY41660.1 - 0.00042 20.8 1.0 0.00056 20.4 0.4 1.5 2 0 0 2 2 2 1 Phospholipase A2 PTCB-BRCT PF12738.7 CBY41661.1 - 7e-20 70.7 0.2 3.5e-12 46.1 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 CBY41661.1 - 1.1e-16 60.9 0.0 4.7e-07 30.1 0.0 3.8 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBY41661.1 - 8.4e-10 38.9 0.2 0.0016 18.8 0.0 4.2 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY41661.1 - 0.0043 17.3 0.3 6.6 7.1 0.0 3.1 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain DUF5437 PF17505.2 CBY41661.1 - 0.15 12.2 0.3 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5437) SWIRM-assoc_2 PF16496.5 CBY41661.1 - 0.45 9.3 9.3 1.3 7.8 8.8 1.8 1 1 1 2 2 2 0 SWIRM-associated domain at the N-terminal LSM PF01423.22 CBY41662.1 - 7.2e-13 48.0 0.3 8.5e-13 47.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain PMP22_Claudin PF00822.20 CBY41663.1 - 1.6e-07 31.3 7.5 2.5e-07 30.7 7.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2208 PF09973.9 CBY41663.1 - 0.022 14.4 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) GWT1 PF06423.12 CBY41663.1 - 0.089 12.9 0.1 0.089 12.9 0.1 1.5 2 0 0 2 2 2 0 GWT1 DNA_pol_D_N PF18018.1 CBY41664.1 - 1.3e-26 93.2 0.1 1.9e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Nop52 PF05997.12 CBY41665.1 - 6.7e-50 169.9 0.1 8.4e-50 169.5 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF4712 PF15830.5 CBY41665.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) SMC_ScpB PF04079.16 CBY41666.1 - 0.049 13.3 0.2 3.5 7.2 0.0 2.2 2 1 0 2 2 2 0 Segregation and condensation complex subunit ScpB DUF2457 PF10446.9 CBY41666.1 - 0.42 9.7 9.8 0.52 9.4 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_1 PF00036.32 CBY41668.1 - 2.8e-08 32.7 1.0 0.00013 21.3 0.1 3.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY41668.1 - 1.5e-06 28.5 0.9 0.0086 16.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBY41668.1 - 3e-05 23.6 7.2 0.0011 18.8 0.3 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBY41668.1 - 0.0002 21.1 0.2 0.0057 16.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY41668.1 - 0.00022 20.5 0.1 0.00022 20.5 0.1 3.3 3 0 0 3 3 3 2 EF hand 4HBT_3 PF13622.6 CBY41669.1 - 6.4 6.9 9.0 0.18 12.0 2.1 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily EF-hand_6 PF13405.6 CBY41670.1 - 1.5e-07 30.8 1.2 9.2e-06 25.2 0.2 3.3 3 1 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBY41670.1 - 4.5e-06 27.0 4.4 4.6e-06 27.0 2.7 1.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY41670.1 - 4.6e-06 25.8 0.3 4.6e-06 25.8 0.3 3.2 4 0 0 4 4 4 1 EF hand EFhand_Ca_insen PF08726.10 CBY41670.1 - 2.1e-05 24.5 0.0 6.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 CBY41670.1 - 0.0029 17.4 1.2 2 8.3 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair Herpes_US12 PF05363.12 CBY41670.1 - 0.038 14.7 0.0 0.064 14.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus US12 family MAR_sialic_bdg PF10564.9 CBY41670.1 - 0.098 12.7 0.6 0.27 11.3 0.2 1.8 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat PCRF PF03462.18 CBY41671.1 - 6.3e-08 32.7 0.4 8e-08 32.4 0.4 1.1 1 0 0 1 1 1 1 PCRF domain Antigen_Bd37 PF11641.8 CBY41671.1 - 0.061 12.8 1.0 0.086 12.3 1.0 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Adipogenin PF15202.6 CBY41671.1 - 0.073 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Adipogenin MRP-L28 PF09812.9 CBY41671.1 - 0.12 12.5 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF5104 PF17117.5 CBY41671.1 - 0.18 12.3 3.4 5.4 7.5 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5104) Glutaminase PF04960.15 CBY41672.1 - 2e-92 309.4 0.0 3.1e-92 308.8 0.0 1.2 1 0 0 1 1 1 1 Glutaminase U3_assoc_6 PF08640.11 CBY41672.1 - 0.062 13.4 0.3 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 DUF4550 PF15084.6 CBY41674.1 - 8.3e-26 90.2 0.9 3.1e-25 88.4 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4550) Crinivirus_P26 PF07416.11 CBY41674.1 - 0.016 15.0 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Crinivirus P26 protein cNMP_binding PF00027.29 CBY41675.1 - 2.2e-37 127.0 0.2 1e-18 67.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CBY41675.1 - 2e-08 33.8 0.3 5.2e-08 32.4 0.3 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBY41675.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif Cupin_2 PF07883.11 CBY41675.1 - 0.14 11.9 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Cupin domain MitoNEET_N PF10660.9 CBY41675.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus 2-oxoacid_dh PF00198.23 CBY41676.1 - 7.7e-78 261.1 0.3 1e-77 260.7 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBY41676.1 - 1.7e-18 66.2 4.7 8.3e-12 44.8 0.3 2.8 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.17 CBY41676.1 - 1.3e-11 44.6 0.3 3.7e-11 43.2 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Phospholip_A2_1 PF00068.19 CBY41677.1 - 3.4e-10 40.4 6.8 3.4e-10 40.4 6.8 2.5 2 0 0 2 2 2 1 Phospholipase A2 VWA PF00092.28 CBY41677.1 - 4.2e-08 33.6 1.1 5.2e-08 33.3 0.2 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY41677.1 - 0.00061 20.4 2.3 0.0022 18.6 0.1 2.7 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CBY41677.1 - 0.015 14.7 1.1 0.04 13.3 1.1 1.6 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein EGF_2 PF07974.13 CBY41677.1 - 0.021 15.2 8.8 0.021 15.2 8.8 3.1 3 0 0 3 3 3 0 EGF-like domain DUF676 PF05057.14 CBY41678.1 - 9.2e-07 28.6 0.6 3.2e-06 26.8 0.6 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CBY41678.1 - 1.3e-06 28.4 0.0 3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CBY41678.1 - 4.4e-06 26.2 0.0 2.5e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 CBY41678.1 - 0.00028 20.2 0.3 0.00052 19.3 0.3 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.16 CBY41678.1 - 0.00078 19.3 0.2 0.0091 15.8 0.2 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBY41678.1 - 0.0012 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 CBY41678.1 - 0.006 16.1 0.1 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 CBY41678.1 - 0.008 16.8 0.0 0.012 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 CBY41678.1 - 0.01 15.4 0.1 0.085 12.4 0.0 2.2 2 1 0 2 2 2 0 Lipase (class 2) LIDHydrolase PF10230.9 CBY41678.1 - 0.035 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CBY41678.1 - 0.045 13.4 0.0 0.16 11.6 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 CBY41678.1 - 0.046 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CBY41678.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 CBY41678.1 - 0.071 12.9 0.2 0.63 9.8 0.1 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBY41678.1 - 0.075 12.5 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 CBY41678.1 - 0.09 12.6 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase UPF0121 PF03661.13 CBY41679.1 - 1.7e-61 207.7 13.6 2.1e-61 207.4 13.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-DNL PF05180.12 CBY41680.1 - 1.6e-09 37.6 0.2 2.8e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 DNL zinc finger U5_2-snRNA_bdg PF10597.9 CBY41680.1 - 0.0039 17.2 0.0 0.02 15.0 0.0 1.9 1 1 1 2 2 2 1 U5-snRNA binding site 2 of PrP8 BTB PF00651.31 CBY41680.1 - 0.041 14.1 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-AN1 PF01428.16 CBY41680.1 - 0.11 12.7 2.9 1.2 9.4 0.4 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-HIT PF04438.16 CBY41680.1 - 4.8 7.1 9.5 11 6.0 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger DUF4131 PF13567.6 CBY41681.1 - 0.12 12.0 0.4 0.18 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Auto_anti-p27 PF06677.12 CBY41682.1 - 0.02 15.0 1.2 0.037 14.2 1.2 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf_UBZ PF18439.1 CBY41682.1 - 0.037 13.6 2.2 0.33 10.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 CBY41682.1 - 0.066 13.1 2.2 0.1 12.5 2.2 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Terminase_GpA PF05876.12 CBY41682.1 - 0.12 10.9 0.2 0.12 10.9 0.2 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DpnI PF06044.12 CBY41682.1 - 0.2 11.3 2.5 0.25 10.9 2.5 1.1 1 0 0 1 1 1 0 Dam-replacing family zf-ribbon_3 PF13248.6 CBY41682.1 - 0.28 10.7 4.8 0.65 9.5 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.7 CBY41682.1 - 0.3 11.6 5.2 8 7.0 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CBY41682.1 - 0.37 11.3 6.0 6 7.5 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CBY41682.1 - 1 9.8 6.6 8.8 6.8 2.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CBY41682.1 - 2.3 8.4 6.1 8.9 6.5 0.6 2.3 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 CBY41682.1 - 3.2 8.8 5.5 21 6.3 0.0 2.6 3 0 0 3 3 2 0 C2H2-type zinc finger zf-UBR PF02207.20 CBY41683.1 - 0.02 15.0 6.3 0.038 14.2 6.3 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Ank_5 PF13857.6 CBY41684.1 - 0.025 14.9 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) LMBR1 PF04791.16 CBY41684.1 - 6.9 5.5 5.1 5.1 5.9 0.5 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein ELO PF01151.18 CBY41688.1 - 7.9e-44 150.1 16.2 9.4e-44 149.8 16.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CENP-O PF09496.10 CBY41688.1 - 0.1 12.5 0.4 0.15 12.0 0.4 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component NICE-3 PF07406.11 CBY41689.1 - 1.6e-06 28.3 0.0 1.8e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 NICE-3 protein BORCS6 PF10157.9 CBY41689.1 - 0.083 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 HOOK PF05622.12 CBY41690.1 - 4.6e-54 183.8 12.9 5.3e-54 183.6 12.9 1.0 1 0 0 1 1 1 1 HOOK protein Tho2 PF11262.8 CBY41690.1 - 0.086 12.0 6.5 0.026 13.8 3.7 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Spc7 PF08317.11 CBY41690.1 - 2.2 7.1 15.6 0.3 9.9 11.3 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CBY41690.1 - 6.1 6.9 16.8 0.36 10.9 8.7 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding rve PF00665.26 CBY41692.1 - 6.5e-18 65.0 0.0 1.2e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY41692.1 - 3.8e-08 33.3 1.2 7.3e-08 32.4 0.3 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RUN PF02759.19 CBY41693.1 - 2.2e-20 73.0 0.0 1.6e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 RUN domain DENN PF02141.21 CBY41693.1 - 1.3e-19 70.9 5.4 1.3e-19 70.9 5.4 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 CBY41693.1 - 1.5e-10 40.9 2.1 3.9e-10 39.6 2.1 1.7 1 0 0 1 1 1 1 dDENN domain PLAT PF01477.23 CBY41693.1 - 4.4e-10 40.1 0.0 9.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PLAT/LH2 domain uDENN PF03456.18 CBY41693.1 - 0.1 13.3 0.0 0.3 11.9 0.0 1.9 1 0 0 1 1 1 0 uDENN domain Mod_r PF07200.13 CBY41694.1 - 1.3 9.1 7.7 0.97 9.5 5.5 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Kazal_1 PF00050.21 CBY41696.1 - 3.4e-32 110.2 23.4 1e-09 38.2 1.3 5.2 3 2 2 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY41696.1 - 1.5e-31 108.2 22.3 3.4e-10 39.9 2.2 5.1 4 1 1 5 5 5 4 Kazal-type serine protease inhibitor domain GATA PF00320.27 CBY41697.1 - 0.003 17.1 3.9 0.048 13.3 0.1 2.4 2 0 0 2 2 2 2 GATA zinc finger Peptidase_S39 PF02122.15 CBY41697.1 - 0.18 11.3 0.7 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase S39 ABC_membrane PF00664.23 CBY41698.1 - 3.6e-50 171.2 3.6 9.7e-50 169.7 3.6 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region DUF2795 PF11387.8 CBY41698.1 - 0.0028 17.8 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2795) Tad PF13400.6 CBY41698.1 - 2.3 8.6 4.4 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like ANF_receptor PF01094.28 CBY41699.1 - 8.5e-38 130.4 2.5 1e-37 130.1 2.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region NHL PF01436.21 CBY41700.1 - 0.0094 15.9 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 NHL repeat SdiA-regulated PF06977.11 CBY41700.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 SdiA-regulated zf-NADH-PPase PF09297.11 CBY41700.1 - 0.59 9.8 3.3 2 8.1 0.1 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Neur_chan_memb PF02932.16 CBY41701.1 - 7e-18 65.6 4.7 4.1e-12 46.7 1.8 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region SelK_SelG PF10961.8 CBY41701.1 - 0.31 11.7 3.0 1.8 9.2 3.0 2.2 1 1 0 1 1 1 0 Selenoprotein SelK_SelG Abhydrolase_1 PF00561.20 CBY41702.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ras PF00071.22 CBY41703.1 - 5.9e-57 191.8 0.1 6.9e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY41703.1 - 6e-35 120.1 0.0 1e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY41703.1 - 3.9e-16 59.0 0.0 4.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBY41703.1 - 2.2e-07 30.9 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBY41703.1 - 1.6e-06 27.8 0.0 3e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBY41703.1 - 1.8e-06 27.5 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY41703.1 - 6.2e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CBY41703.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 CBY41703.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CBY41703.1 - 0.026 14.0 0.5 0.042 13.3 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CBY41703.1 - 0.027 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CBY41703.1 - 0.045 13.5 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBY41703.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 CBY41703.1 - 0.067 12.3 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CBY41703.1 - 0.14 12.7 0.2 0.27 11.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter DUF4023 PF13215.6 CBY41703.1 - 0.47 10.5 5.7 0.82 9.7 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) 5-nucleotidase PF06189.12 CBY41704.1 - 4.4e-60 202.9 0.0 5.4e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 5'-nucleotidase Phosducin PF02114.16 CBY41704.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosducin Pkinase PF00069.25 CBY41705.1 - 3.9e-08 33.0 0.3 5.7e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41705.1 - 0.00069 19.0 0.0 0.00089 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase O-FucT PF10250.9 CBY41706.1 - 2.3e-08 34.1 0.0 5.9e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cu-oxidase_2 PF07731.14 CBY41706.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase T2SSG PF08334.11 CBY41707.1 - 0.096 12.8 0.3 0.096 12.8 0.3 1.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein G Exonuc_VII_L PF02601.15 CBY41707.1 - 0.17 11.5 5.5 0.2 11.2 5.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5339 PF17274.2 CBY41707.1 - 2.4 9.1 10.4 9.9 7.1 1.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5339) PLAC8 PF04749.17 CBY41708.1 - 0.033 15.2 13.9 0.045 14.8 13.9 1.2 1 0 0 1 1 1 0 PLAC8 family CD52 PF15116.6 CBY41708.1 - 0.18 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen DUF1295 PF06966.12 CBY41709.1 - 5.8e-45 153.6 1.7 6.9e-45 153.4 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CBY41709.1 - 0.021 15.2 0.4 0.064 13.7 0.0 2.1 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MerC PF03203.14 CBY41709.1 - 0.035 14.5 0.2 0.035 14.5 0.2 1.8 2 0 0 2 2 2 0 MerC mercury resistance protein PEMT PF04191.13 CBY41709.1 - 0.059 13.8 2.4 0.073 13.5 0.3 2.3 2 1 0 2 2 2 0 Phospholipid methyltransferase PDZ PF00595.24 CBY41710.1 - 1.6e-20 73.2 0.0 2.1e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY41710.1 - 2e-16 59.6 0.1 1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY41710.1 - 3.5e-05 24.0 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY41710.1 - 0.01 15.8 0.0 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain Ion_trans PF00520.31 CBY41711.1 - 7.7e-07 28.6 8.7 9.9e-07 28.2 8.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 CBY41712.1 - 0.0028 16.9 0.5 0.0044 16.3 0.3 1.4 1 1 0 1 1 1 1 Ion transport protein EF-hand_8 PF13833.6 CBY41712.1 - 0.052 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 CBY41713.1 - 6.4e-46 153.4 33.1 2.8e-07 31.1 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CBY41713.1 - 9.4e-14 51.0 0.9 1.8e-13 50.2 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CBY41713.1 - 4.3e-12 46.2 7.3 0.068 13.5 0.1 6.6 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CBY41713.1 - 2.5e-11 43.1 0.3 5.4e-11 42.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CBY41713.1 - 8.4e-08 31.3 17.8 0.015 14.0 0.6 6.0 3 2 2 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CBY41713.1 - 5.7e-06 26.1 7.1 0.003 17.2 2.3 3.5 2 2 0 2 2 2 2 PQQ-like domain FAM83 PF07894.12 CBY41713.1 - 0.0099 15.5 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 1 FAM83 A-H DUF5046 PF16465.5 CBY41713.1 - 0.041 13.3 0.6 7 6.0 0.1 3.4 1 1 2 4 4 4 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 CBY41713.1 - 0.049 14.1 4.9 8.3 7.0 0.0 5.4 5 3 1 6 6 6 0 PQQ-like domain PQQ PF01011.21 CBY41713.1 - 0.077 13.0 1.3 1e+02 3.1 0.0 5.2 6 0 0 6 6 5 0 PQQ enzyme repeat PRANC PF09372.10 CBY41713.1 - 0.12 12.7 0.2 0.34 11.2 0.2 1.8 1 0 0 1 1 1 0 PRANC domain NADHdh PF00146.21 CBY41714.1 - 0.0034 16.7 0.7 0.0034 16.7 0.7 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Zona_pellucida PF00100.23 CBY41716.1 - 2.7e-16 60.2 7.1 2.9e-16 60.1 7.1 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain Fzo_mitofusin PF04799.13 CBY41717.1 - 0.076 12.6 0.0 0.086 12.4 0.0 1.0 1 0 0 1 1 1 0 fzo-like conserved region DUF1764 PF08576.10 CBY41718.1 - 0.037 14.9 8.4 0.067 14.1 8.4 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1700 PF08006.11 CBY41718.1 - 0.13 11.8 1.6 0.17 11.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3027 PF11228.8 CBY41718.1 - 0.16 12.0 2.8 0.22 11.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Fe-ADH PF00465.19 CBY41718.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase UPAR_LY6 PF00021.21 CBY41718.1 - 0.5 11.1 12.1 1.1 10.0 12.1 1.7 1 1 0 1 1 1 0 u-PAR/Ly-6 domain LRR_4 PF12799.7 CBY41719.1 - 0.012 16.0 1.6 4.1 8.0 0.0 3.6 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) BCDHK_Adom3 PF10436.9 CBY41720.1 - 6.2e-17 61.9 0.5 9.9e-17 61.2 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBY41720.1 - 8e-10 39.2 0.0 2.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY41720.1 - 3e-05 23.9 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CBY41720.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF447 PF04289.12 CBY41720.1 - 0.039 13.7 0.3 0.076 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF447) UTP25 PF06862.12 CBY41721.1 - 1.3e-86 291.3 1.9 1.5e-86 291.1 1.9 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 rve PF00665.26 CBY41722.1 - 6.1e-11 42.5 0.0 1.6e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CBY41722.1 - 0.013 15.8 0.3 0.047 13.9 0.3 2.0 1 0 0 1 1 1 0 DDE domain Zeta_toxin PF06414.12 CBY41722.1 - 0.02 14.2 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 CBY41722.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 CBY41722.1 - 0.078 12.4 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Cortex-I_coil PF09304.10 CBY41723.1 - 0.41 10.9 7.6 0.14 12.4 1.7 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.8 CBY41723.1 - 1.6 8.8 12.4 0.91 9.6 6.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CBY41723.1 - 1.8 7.9 6.6 2.4 7.4 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Yip1 PF04893.17 CBY41724.1 - 2.5e-11 43.6 11.3 2.5e-11 43.6 11.3 1.7 1 1 1 2 2 2 1 Yip1 domain DUF2070 PF09843.9 CBY41724.1 - 8.1 4.6 7.9 11 4.2 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MMS19_C PF12460.8 CBY41725.1 - 1.3e-42 146.4 2.2 2.1e-42 145.7 2.2 1.3 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CBY41725.1 - 0.075 13.6 3.6 3.9 8.1 0.1 4.1 4 1 1 5 5 5 0 HEAT-like repeat MMS19_N PF14500.6 CBY41725.1 - 0.093 12.3 0.4 0.54 9.8 0.1 2.2 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Glyco_hydro_85 PF03644.13 CBY41727.1 - 2.5e-64 217.6 1.3 3.4e-64 217.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Beach PF02138.18 CBY41728.1 - 9.9e-32 110.4 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 CBY41728.1 - 4.3e-08 33.7 17.3 0.008 17.0 0.3 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat GRIM-19 PF06212.12 CBY41728.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 GRIM-19 protein ARID PF01388.21 CBY41730.1 - 7.2e-21 74.7 0.0 1.5e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF5585 PF17823.1 CBY41730.1 - 0.12 11.3 16.0 0.21 10.5 16.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Tankyrase_bdg_C PF15327.6 CBY41730.1 - 0.21 12.0 4.1 6.9 7.1 2.6 2.6 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain HECT PF00632.25 CBY41732.1 - 3.8e-93 312.3 1.2 6.4e-93 311.6 1.2 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SlyX PF04102.12 CBY41732.1 - 0.12 13.0 0.2 0.61 10.7 0.2 2.3 1 0 0 1 1 1 0 SlyX Barttin PF15462.6 CBY41732.1 - 0.96 9.2 4.2 2.1 8.1 4.2 1.5 1 1 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF3083 PF11281.8 CBY41733.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Cys_rich_VLP PF14194.6 CBY41733.1 - 5.3 7.2 9.8 0.91 9.7 4.3 2.2 2 0 0 2 2 2 0 Cysteine-rich VLP Galactosyl_T PF01762.21 CBY41734.1 - 2.2e-30 105.9 0.0 2.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase COesterase PF00135.28 CBY41735.1 - 2.1e-88 297.4 0.0 2.7e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY41735.1 - 4e-07 30.1 0.5 3.8e-06 26.9 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold CUB PF00431.20 CBY41736.1 - 3.6e-10 40.1 0.3 4.5e-10 39.8 0.3 1.1 1 0 0 1 1 1 1 CUB domain Barstar PF01337.18 CBY41736.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Retrotran_gag_3 PF14244.6 CBY41736.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type B56 PF01603.20 CBY41737.1 - 3.8e-58 197.4 2.7 4.3e-58 197.3 2.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) EMC3_TMCO1 PF01956.16 CBY41737.1 - 0.31 10.8 4.2 0.3 10.8 2.7 1.6 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like zf-C4 PF00105.18 CBY41738.1 - 4.5e-21 75.1 13.3 6.8e-21 74.5 13.3 1.2 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) C1_2 PF03107.16 CBY41738.1 - 1.3 9.4 12.4 0.26 11.7 2.2 3.0 1 1 2 3 3 3 0 C1 domain SBF_like PF13593.6 CBY41739.1 - 1.2e-37 130.0 3.3 1.4e-37 129.7 3.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CBY41739.1 - 1.2e-07 31.6 2.6 1.2e-07 31.6 2.6 1.5 2 0 0 2 2 2 1 Sodium Bile acid symporter family COX3 PF00510.18 CBY41739.1 - 0.035 14.0 1.4 0.05 13.4 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III E1-E2_ATPase PF00122.20 CBY41739.1 - 0.092 12.3 0.6 0.17 11.4 0.6 1.4 1 0 0 1 1 1 0 E1-E2 ATPase DnaJ PF00226.31 CBY41741.1 - 3.4e-06 27.1 2.1 0.023 14.8 0.1 2.6 2 1 1 3 3 3 2 DnaJ domain Geminin PF07412.12 CBY41741.1 - 6.6e-06 26.0 4.6 7.7e-06 25.8 4.6 1.0 1 0 0 1 1 1 1 Geminin HAUS6_N PF14661.6 CBY41741.1 - 0.04 13.5 1.3 0.047 13.3 1.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RPT PF13446.6 CBY41741.1 - 0.048 13.6 0.3 0.14 12.1 0.1 1.9 2 1 0 2 2 2 0 A repeated domain in UCH-protein CorA PF01544.18 CBY41741.1 - 0.098 12.0 0.5 0.13 11.5 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein eIF-4B PF06273.11 CBY41741.1 - 0.26 10.3 4.2 0.3 10.1 4.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF1827 PF08860.10 CBY41741.1 - 0.31 11.3 2.6 0.41 10.9 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) HSP70 PF00012.20 CBY41741.1 - 0.72 8.0 4.4 0.84 7.7 4.4 1.0 1 0 0 1 1 1 0 Hsp70 protein RPN7 PF10602.9 CBY41741.1 - 1.5 8.5 7.1 0.5 10.0 4.6 1.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPX2 PF06886.11 CBY41741.1 - 3.2 8.0 12.2 7.5 6.9 12.2 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Tropomodulin PF03250.14 CBY41742.1 - 7e-44 149.3 2.3 1.7e-43 148.1 2.3 1.7 1 0 0 1 1 1 1 Tropomodulin LRR_6 PF13516.6 CBY41742.1 - 0.0025 17.7 2.8 0.028 14.5 0.1 3.0 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 CBY41742.1 - 1.8 9.1 8.0 0.92 10.0 0.4 3.2 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) NACHT PF05729.12 CBY41743.1 - 0.14 12.0 0.1 0.62 10.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain I-set PF07679.16 CBY41744.1 - 9.3e-06 25.6 0.1 1.6e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY41744.1 - 0.00078 20.0 0.1 0.0025 18.4 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin domain Ig_2 PF13895.6 CBY41744.1 - 0.001 19.4 0.1 0.0058 16.9 0.0 2.0 2 0 0 2 2 2 1 Immunoglobulin domain V-set PF07686.17 CBY41744.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin V-set domain Herpes_gE PF02480.16 CBY41744.1 - 0.0023 16.8 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Receptor_2B4 PF11465.8 CBY41744.1 - 0.005 17.0 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 Natural killer cell receptor 2B4 Ig_6 PF18452.1 CBY41744.1 - 0.007 15.9 0.0 0.021 14.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY41744.1 - 0.0087 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin domain Pro_isomerase PF00160.21 CBY41745.1 - 3.3e-45 154.2 0.8 5e-45 153.6 0.3 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.9 CBY41745.1 - 0.0092 15.6 23.4 0.0092 15.6 23.4 2.6 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein Phospholip_A2_1 PF00068.19 CBY41746.1 - 1.4e-20 73.8 6.0 3.2e-20 72.7 6.0 1.6 1 0 0 1 1 1 1 Phospholipase A2 zf-C2H2_4 PF13894.6 CBY41747.1 - 0.00042 20.9 3.3 0.0027 18.4 3.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY41747.1 - 0.0018 18.1 0.3 0.17 11.9 0.1 2.2 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 CBY41747.1 - 0.0035 17.7 4.3 0.024 15.1 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type DUF4674 PF15719.5 CBY41747.1 - 0.0069 16.4 0.1 0.0078 16.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4674) zf-Di19 PF05605.12 CBY41747.1 - 0.0088 16.3 0.3 0.013 15.8 0.3 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 CBY41747.1 - 0.046 14.4 0.1 0.058 14.1 0.1 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CBY41747.1 - 0.45 10.3 8.5 0.28 11.0 5.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FRG1 PF06229.12 CBY41748.1 - 0.99 9.1 6.1 0.89 9.2 3.0 2.1 2 1 0 2 2 2 0 FRG1-like domain DUF441 PF04284.13 CBY41750.1 - 0.002 18.1 0.5 0.0027 17.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF441) BTB PF00651.31 CBY41751.1 - 4.9e-15 55.7 0.8 1.2e-14 54.5 0.8 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF5623 PF18536.1 CBY41751.1 - 0.097 13.0 0.2 5.7 7.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) DUF3007 PF11460.8 CBY41755.1 - 0.067 13.4 1.2 0.88 9.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Phospholip_A2_1 PF00068.19 CBY41756.1 - 5.5e-10 39.7 3.0 5.5e-10 39.7 3.0 1.7 2 0 0 2 2 2 1 Phospholipase A2 PGM_PMM_I PF02878.16 CBY41758.1 - 7.2e-18 64.6 0.2 6.8e-08 32.3 0.0 3.1 2 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CBY41758.1 - 1.4e-10 41.2 0.3 5.3e-10 39.3 0.2 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CBY41758.1 - 3.7e-10 40.0 0.3 7.6e-10 39.0 0.3 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.29 CBY41759.1 - 1.2e-22 80.6 0.1 1.4e-22 80.3 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY41759.1 - 0.0012 18.8 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CBY41759.1 - 0.0097 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain EMP24_GP25L PF01105.24 CBY41761.1 - 9.4e-41 139.7 0.0 1.1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CBY41761.1 - 0.0038 17.4 0.1 0.0054 17.0 0.1 1.3 1 0 0 1 1 1 1 SdrD B-like domain DUF4198 PF10670.9 CBY41761.1 - 0.035 14.5 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF4533 PF15047.6 CBY41763.1 - 0.0002 21.0 2.5 0.042 13.4 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4533) zf-B_box PF00643.24 CBY41763.1 - 0.00034 20.7 10.3 0.0007 19.7 10.3 1.5 1 0 0 1 1 1 1 B-box zinc finger DNA_topoisoIV PF00521.20 CBY41763.1 - 0.00089 18.2 0.9 0.0012 17.8 0.9 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A NYD-SP28_assoc PF14775.6 CBY41763.1 - 0.099 12.8 0.5 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF5347 PF17282.2 CBY41763.1 - 0.1 12.9 1.2 0.23 11.8 1.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5347) Bro-N PF02498.17 CBY41763.1 - 0.34 11.6 2.1 0.42 11.3 0.2 2.2 2 1 1 3 3 3 0 BRO family, N-terminal domain RSS_P20 PF11757.8 CBY41763.1 - 0.74 10.3 9.0 2.4 8.7 3.0 2.9 2 1 1 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain DUF1043 PF06295.12 CBY41763.1 - 0.77 9.8 6.1 0.7 9.9 3.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF2703 PF10865.8 CBY41763.1 - 2.4 8.4 6.4 1.6 9.0 3.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2703) DnaJ PF00226.31 CBY41766.1 - 2.9e-18 65.8 1.7 6.1e-18 64.7 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain SAC3_GANP PF03399.16 CBY41766.1 - 0.013 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family Wbp11 PF09429.10 CBY41767.1 - 0.86 10.1 3.6 2.6 8.5 0.1 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 Lectin_C PF00059.21 CBY41768.1 - 1.1e-05 26.1 0.2 1.6e-05 25.6 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain Gln_deamidase_2 PF18626.1 CBY41768.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutaminase Sugar_tr PF00083.24 CBY41769.1 - 2.2e-13 49.9 2.0 3.2e-13 49.3 2.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBY41769.1 - 1.2e-09 37.6 8.0 1.2e-09 37.6 8.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily BAR_3_WASP_bdg PF10456.9 CBY41770.1 - 5.5e-21 75.1 0.1 6.1e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PSS PF03034.15 CBY41771.1 - 3.2e-104 348.5 14.5 4.6e-104 348.0 14.5 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase RRM_1 PF00076.22 CBY41772.1 - 1.3e-19 69.8 0.2 2.3e-14 53.0 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 CBY41772.1 - 4.7e-17 61.5 33.3 1.8e-09 37.2 7.5 4.7 4 1 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 CBY41772.1 - 1.8e-06 28.2 21.0 0.001 19.4 2.9 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY41772.1 - 0.00074 19.1 0.9 0.0022 17.5 0.7 1.9 1 1 0 1 1 1 1 Leucine-rich repeat RRM_occluded PF16842.5 CBY41772.1 - 0.0012 18.6 0.0 0.0051 16.7 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CBY41772.1 - 0.0014 18.6 0.1 0.46 10.5 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.6 CBY41772.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_2 PF13532.6 CBY41773.1 - 1.1e-30 107.3 0.0 1.2e-30 107.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBY41773.1 - 0.037 14.5 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NMT_C PF02799.15 CBY41774.1 - 9.5e-77 257.2 0.0 1.5e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CBY41774.1 - 6e-74 247.2 0.0 1e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 CBY41774.1 - 0.00091 19.5 0.0 0.0026 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CBY41774.1 - 0.068 13.2 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY41774.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_F16 PF04708.12 CBY41774.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein Aida_N PF08910.10 CBY41775.1 - 0.033 14.6 0.7 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Aida N-terminus AAA_24 PF13479.6 CBY41775.1 - 0.087 12.5 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain DcpS_C PF11969.8 CBY41775.1 - 0.15 12.6 0.4 0.37 11.3 0.1 1.8 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding His_kinase PF06580.13 CBY41775.1 - 0.21 11.9 1.5 1 9.7 0.1 2.7 2 2 1 3 3 3 0 Histidine kinase Vps16_C PF04840.12 CBY41776.1 - 1.1e-29 103.5 3.8 5.8e-29 101.1 3.8 1.9 1 1 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CBY41776.1 - 2e-26 92.7 0.0 6.6e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Vps16, N-terminal region ECSIT PF06239.11 CBY41777.1 - 6.1e-06 25.5 0.1 1.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway PTPLA PF04387.14 CBY41779.1 - 1.4e-35 122.5 1.2 2.4e-35 121.7 1.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Connexin PF00029.19 CBY41779.1 - 0.04 13.7 2.6 2.2 8.0 0.5 2.2 2 0 0 2 2 2 0 Connexin Astacin PF01400.24 CBY41781.1 - 7.8e-35 120.2 0.0 9.4e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.6 CBY41781.1 - 2.2e-05 24.2 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CBY41781.1 - 0.0012 19.4 0.5 0.0018 18.8 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CBY41781.1 - 0.013 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CBY41781.1 - 0.025 14.7 0.2 0.034 14.3 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 CBY41781.1 - 0.037 13.3 0.4 0.054 12.7 0.4 1.2 1 0 0 1 1 1 0 Met-zincin DUF3152 PF11350.8 CBY41781.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin_2 PF13574.6 CBY41781.1 - 0.082 12.8 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M8 PF01457.16 CBY41781.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin PTR2 PF00854.21 CBY41782.1 - 6.8e-59 199.7 11.6 9.7e-31 107.0 1.3 2.1 1 1 1 2 2 2 2 POT family DUF1798 PF08807.10 CBY41782.1 - 0.19 11.9 0.2 0.31 11.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Mob1_phocein PF03637.17 CBY41784.1 - 5e-63 212.1 0.2 6.2e-63 211.8 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Hep_core_N PF08290.11 CBY41784.1 - 0.14 12.1 0.2 0.4 10.7 0.2 1.8 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Archease PF01951.16 CBY41785.1 - 2.2e-35 121.9 1.1 4.5e-35 120.9 0.4 1.9 2 0 0 2 2 2 1 Archease protein family (MTH1598/TM1083) Ank_2 PF12796.7 CBY41785.1 - 3e-05 24.5 0.1 0.0021 18.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3782 PF12644.7 CBY41785.1 - 0.032 14.4 0.4 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) Ank_3 PF13606.6 CBY41785.1 - 0.044 14.3 0.0 0.32 11.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Mad3_BUB1_II PF08171.11 CBY41785.1 - 0.068 13.3 1.4 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 SH2 PF00017.24 CBY41789.1 - 2.4e-07 30.7 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SOCS_box PF07525.16 CBY41789.1 - 0.08 13.3 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 SOCS box Tubulin PF00091.25 CBY41790.1 - 1.1e-67 228.1 0.0 1.8e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY41790.1 - 2.5e-42 144.0 0.1 4.1e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBY41790.1 - 9.8e-06 25.9 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CBY41790.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CBY41790.1 - 0.034 13.3 0.0 0.089 12.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin like TrmK PF04816.12 CBY41790.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase PX PF00787.24 CBY41793.1 - 4.2e-08 33.1 0.1 5e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 PX domain Collagen PF01391.18 CBY41794.1 - 1.5e-26 91.9 82.0 1.9e-09 37.1 23.1 3.6 2 2 1 3 3 3 3 Collagen triple helix repeat (20 copies) COX4 PF02936.14 CBY41795.1 - 2.3e-12 47.1 0.4 6.9e-12 45.6 0.4 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.10 CBY41795.1 - 0.0093 16.5 0.1 0.14 12.7 0.0 2.2 2 0 0 2 2 2 1 HMG-box domain AAR2 PF05282.11 CBY41796.1 - 1.8e-50 172.3 0.2 2.9e-50 171.7 0.2 1.3 1 1 0 1 1 1 1 AAR2 protein Mesd PF10185.9 CBY41798.1 - 0.049 13.6 0.6 0.066 13.2 0.6 1.1 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Mesd PF10185.9 CBY41799.1 - 7.6e-14 51.9 2.5 1.1e-13 51.5 2.3 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor zf-C3HC4_3 PF13920.6 CBY41800.1 - 5.6e-08 32.5 10.6 8.6e-08 31.9 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPA PF08616.10 CBY41800.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis zf-RING_2 PF13639.6 CBY41800.1 - 0.94 9.9 13.1 1.7 9.0 13.1 1.4 1 0 0 1 1 1 0 Ring finger domain SURF2 PF05477.11 CBY41803.1 - 4.6 6.9 7.2 6.3 6.4 7.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) bZIP_2 PF07716.15 CBY41805.1 - 1.4e-14 53.9 10.9 1.4e-14 53.9 10.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CBY41805.1 - 1.6e-05 24.9 11.0 1.6e-05 24.9 11.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor Alpha-mann_mid PF09261.11 CBY41805.1 - 0.0048 17.0 0.9 0.0099 16.0 0.5 1.8 1 1 0 1 1 1 1 Alpha mannosidase middle domain NAM-associated PF14303.6 CBY41805.1 - 0.012 16.3 8.9 0.012 16.3 8.9 1.6 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain FXR_C1 PF16096.5 CBY41805.1 - 0.017 15.4 0.3 0.017 15.4 0.3 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 IMUP PF15761.5 CBY41805.1 - 0.55 10.9 5.9 0.86 10.3 5.3 1.7 1 1 0 1 1 1 0 Immortalisation up-regulated protein bZIP_Maf PF03131.17 CBY41805.1 - 1.9 9.0 13.7 0.54 10.8 9.1 2.3 2 1 1 3 3 3 0 bZIP Maf transcription factor FAM194 PF14977.6 CBY41806.1 - 0.11 11.9 0.0 0.54 9.5 0.0 2.0 1 1 0 1 1 1 0 FAM194 protein 2OG-FeII_Oxy PF03171.20 CBY41807.1 - 9.4e-16 58.1 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBY41807.1 - 8.4e-09 36.2 0.1 2.2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4077 PF13295.6 CBY41810.1 - 0.069 13.1 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) HSP90 PF00183.18 CBY41812.1 - 2.3e-106 356.8 4.2 2.8e-106 356.5 4.2 1.0 1 0 0 1 1 1 1 Hsp90 protein PHD PF00628.29 CBY41814.1 - 1.2 9.1 18.7 0.034 14.0 11.4 2.3 2 0 0 2 2 2 0 PHD-finger FXMRP1_C_core PF12235.8 CBY41814.1 - 6.9 7.3 21.9 0.27 11.9 8.0 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Sulfotransfer_4 PF17784.1 CBY41816.1 - 1e-18 68.0 0.0 1.1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Snapin_Pallidin PF14712.6 CBY41817.1 - 3.7e-07 30.5 11.9 5.1e-05 23.6 0.6 4.8 3 2 1 4 4 4 1 Snapin/Pallidin PspA_IM30 PF04012.12 CBY41817.1 - 0.00058 19.5 24.0 0.0069 16.0 11.8 3.1 1 1 2 3 3 3 1 PspA/IM30 family Baculo_PEP_C PF04513.12 CBY41817.1 - 0.00059 19.9 20.4 0.045 13.8 4.0 4.4 1 1 4 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CBY41817.1 - 0.00072 20.0 23.6 0.0025 18.3 1.5 5.4 3 2 2 5 5 5 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 CBY41817.1 - 0.00075 19.5 10.3 0.00075 19.5 10.3 4.5 2 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 CBY41817.1 - 0.0015 18.7 28.2 0.015 15.5 1.3 4.3 1 1 3 4 4 4 2 Tropomyosin like Prefoldin PF02996.17 CBY41817.1 - 0.0033 17.3 15.2 1.2 9.1 0.4 4.7 4 0 0 4 4 4 2 Prefoldin subunit ATG16 PF08614.11 CBY41817.1 - 0.0034 17.6 10.2 0.0034 17.6 10.2 3.4 2 2 0 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBY41817.1 - 0.0034 16.3 26.0 0.076 11.9 2.0 3.6 1 1 3 4 4 4 3 Spc7 kinetochore protein DUF4407 PF14362.6 CBY41817.1 - 0.0036 16.7 12.5 0.029 13.7 2.6 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBY41817.1 - 0.0053 16.8 24.7 0.75 9.8 2.0 5.2 1 1 2 4 4 4 3 Protein of unknown function (DUF1664) YkyA PF10368.9 CBY41817.1 - 0.0077 15.9 18.8 0.012 15.3 2.9 2.7 2 1 0 2 2 2 2 Putative cell-wall binding lipoprotein DUF948 PF06103.11 CBY41817.1 - 0.024 14.9 16.8 0.79 10.0 0.2 4.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 CBY41817.1 - 0.028 14.0 13.1 0.73 9.3 0.7 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Laminin_II PF06009.12 CBY41817.1 - 0.035 14.1 20.7 1.2 9.2 5.1 4.8 2 2 4 6 6 6 0 Laminin Domain II EzrA PF06160.12 CBY41817.1 - 0.037 12.2 20.5 0.017 13.3 15.5 3.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 CBY41817.1 - 0.041 14.0 8.5 0.48 10.6 0.2 4.5 3 2 2 5 5 4 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 CBY41817.1 - 0.054 13.6 23.5 0.4 10.7 1.2 4.0 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 CBY41817.1 - 0.061 13.6 0.6 0.061 13.6 0.6 4.9 3 2 2 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CBY41817.1 - 0.062 13.5 19.4 0.36 11.0 0.4 4.0 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4988 PF16378.5 CBY41817.1 - 0.071 12.8 5.6 12 5.5 0.1 3.7 3 2 0 3 3 3 0 Domain of unknown function Adenine_deam_C PF13382.6 CBY41817.1 - 0.079 12.3 0.6 7.6 5.9 0.4 3.1 3 0 0 3 3 3 0 Adenine deaminase C-terminal domain TolA_bind_tri PF16331.5 CBY41817.1 - 0.11 12.6 0.2 0.11 12.6 0.2 4.8 4 1 1 5 5 4 0 TolA binding protein trimerisation Filament PF00038.21 CBY41817.1 - 0.12 11.9 24.8 0.87 9.1 16.9 3.9 1 1 1 2 2 2 0 Intermediate filament protein DUF2536 PF10750.9 CBY41817.1 - 0.13 12.2 1.8 0.3 11.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Prominin PF05478.11 CBY41817.1 - 0.14 10.1 16.9 0.16 9.9 4.4 2.8 1 1 2 3 3 3 0 Prominin Collagen_mid PF15984.5 CBY41817.1 - 0.14 11.9 2.8 0.7 9.6 2.0 2.3 2 1 1 3 3 3 0 Bacterial collagen, middle region DUF4472 PF14739.6 CBY41817.1 - 0.28 11.9 19.7 4 8.2 1.3 4.5 3 1 2 5 5 5 0 Domain of unknown function (DUF4472) UPF0242 PF06785.11 CBY41817.1 - 0.29 11.2 23.3 0.45 10.6 0.4 3.3 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 CBY41817.1 - 0.44 10.9 11.7 2.6 8.4 0.1 4.9 3 1 2 5 5 5 0 Uncharacterized conserved protein DUF4618 PF15397.6 CBY41817.1 - 0.47 9.8 20.1 0.075 12.5 5.8 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) HrpB7 PF09486.10 CBY41817.1 - 0.81 10.1 17.3 4.6 7.6 2.4 3.3 2 2 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF16 PF01519.16 CBY41817.1 - 0.89 10.1 17.7 0.58 10.7 1.8 4.5 1 1 1 2 2 1 0 Protein of unknown function DUF16 DUF3450 PF11932.8 CBY41817.1 - 1.7 7.9 23.8 0.1 11.9 1.8 4.1 3 2 1 5 5 4 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 CBY41817.1 - 2.1 7.9 23.1 34 4.0 14.9 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2730 PF10805.8 CBY41817.1 - 2.8 8.1 11.1 0.55 10.4 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) CorA PF01544.18 CBY41817.1 - 3.1 7.0 14.4 0.39 10.0 6.3 2.6 2 2 0 2 2 2 0 CorA-like Mg2+ transporter protein Ax_dynein_light PF10211.9 CBY41817.1 - 3.4 7.6 15.2 1.1 9.2 0.2 3.6 3 2 1 4 4 4 0 Axonemal dynein light chain APG6_N PF17675.1 CBY41817.1 - 3.5 8.2 29.0 0.84 10.2 0.8 4.0 3 1 0 4 4 4 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 CBY41817.1 - 3.6 7.8 21.9 0.72 10.1 7.6 4.0 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 DUF4140 PF13600.6 CBY41817.1 - 5.2 7.6 19.8 0.92 10.0 1.3 4.1 3 2 2 5 5 4 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CBY41817.1 - 6.1 7.3 26.4 4.6 7.7 0.5 6.5 4 2 0 5 5 5 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBY41817.1 - 6.6 6.6 17.3 5 7.0 1.2 4.5 5 0 0 5 5 5 0 Septum formation initiator XhlA PF10779.9 CBY41817.1 - 6.7 7.0 20.0 1.6 9.0 0.4 5.3 5 2 1 6 6 6 0 Haemolysin XhlA Syntaxin_2 PF14523.6 CBY41817.1 - 6.8 7.1 16.8 3.8 7.9 1.0 4.1 2 2 2 4 4 4 0 Syntaxin-like protein BST2 PF16716.5 CBY41817.1 - 7 7.3 17.8 6.6 7.4 0.4 4.7 4 1 0 5 5 4 0 Bone marrow stromal antigen 2 Vac_Fusion PF02346.16 CBY41817.1 - 8.6 6.1 7.1 11 5.7 0.3 4.2 4 1 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Sec34 PF04136.15 CBY41817.1 - 8.7 6.2 20.6 0.6 10.0 1.2 4.4 2 2 1 4 4 4 0 Sec34-like family CREPT PF16566.5 CBY41817.1 - 9.1 6.4 15.6 3.5 7.8 0.1 3.8 3 2 1 4 4 3 0 Cell-cycle alteration and expression-elevated protein in tumour A2M_recep PF07677.14 CBY41820.1 - 6.8e-10 39.5 0.3 9.9e-10 39.0 0.3 1.3 1 0 0 1 1 1 1 A-macroglobulin receptor binding domain ECH_1 PF00378.20 CBY41821.1 - 4.3e-50 170.4 0.1 5.3e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBY41821.1 - 3.8e-27 95.7 0.0 9.4e-27 94.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Trypsin PF00089.26 CBY41822.1 - 1.2e-31 110.3 0.2 2.4e-31 109.3 0.2 1.6 1 0 0 1 1 1 1 Trypsin Uteroglobin PF01099.17 CBY41822.1 - 0.0077 16.6 0.1 0.02 15.2 0.1 1.6 1 0 0 1 1 1 1 Uteroglobin family C2 PF00168.30 CBY41823.1 - 8.2e-10 38.9 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain dsrm PF00035.26 CBY41824.1 - 6.4e-11 42.8 0.6 2.4 8.9 0.0 6.4 6 0 0 6 6 6 4 Double-stranded RNA binding motif HAT PF02184.16 CBY41825.1 - 6e-41 138.1 64.7 1.2e-14 53.9 0.7 15.8 15 3 0 15 15 15 6 HAT (Half-A-TPR) repeat Suf PF05843.14 CBY41825.1 - 3.6e-24 86.3 21.3 1.6e-05 25.0 0.8 7.5 2 2 5 7 7 7 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CBY41825.1 - 2.6e-23 80.7 39.3 0.083 13.8 0.4 16.6 7 4 11 18 18 18 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBY41825.1 - 6.5e-17 61.8 0.3 0.22 12.1 0.1 9.5 5 3 7 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBY41825.1 - 7.3e-13 47.9 6.7 0.011 16.0 0.0 8.5 12 0 0 12 12 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBY41825.1 - 1.6e-07 31.8 11.9 9.2 7.0 0.1 9.8 9 3 1 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBY41825.1 - 1.9e-06 27.6 4.8 72 4.0 0.0 10.2 13 0 0 13 13 11 0 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 CBY41825.1 - 2.2e-06 26.2 0.0 0.04 12.2 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus TPR_2 PF07719.17 CBY41825.1 - 5.2e-06 26.2 34.3 2.7 8.3 0.7 13.2 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBY41825.1 - 0.0001 22.4 10.6 0.44 10.7 0.1 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBY41825.1 - 0.00031 21.0 21.2 3.7 7.9 0.0 9.8 12 2 1 13 13 12 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY41825.1 - 0.00039 20.9 26.4 19 6.1 0.1 13.2 17 0 0 17 17 14 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBY41825.1 - 0.0048 16.9 24.4 0.012 15.6 0.7 6.5 6 3 2 8 8 6 2 Mad3/BUB1 homology region 1 Fis1_TPR_C PF14853.6 CBY41825.1 - 0.0062 16.6 13.7 2.7 8.2 0.1 6.7 8 0 0 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat DUF3410 PF11890.8 CBY41825.1 - 0.0072 16.1 0.8 6.2 6.7 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3410) LPD39 PF18858.1 CBY41825.1 - 0.01 15.9 2.2 3.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 DUF3151 PF11349.8 CBY41825.1 - 0.031 14.4 2.9 9.3 6.4 0.0 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF3151) Enolase_like_N PF18374.1 CBY41825.1 - 0.051 13.0 1.7 12 5.4 0.1 3.1 2 0 0 2 2 2 0 Enolase N-terminal domain-like ZNRF_3_ecto PF18212.1 CBY41825.1 - 0.065 13.2 0.1 2 8.4 0.0 3.6 6 0 0 6 6 3 0 ZNRF-3 Ectodomain MIT PF04212.18 CBY41825.1 - 0.45 10.6 8.4 12 6.1 0.1 4.6 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 CBY41825.1 - 0.61 9.4 8.3 0.72 9.2 0.8 3.9 4 0 0 4 4 4 0 MalT-like TPR region QueH PF02677.14 CBY41825.1 - 1.4 9.0 8.4 0.19 11.8 1.9 2.8 3 0 0 3 3 3 0 Epoxyqueuosine reductase QueH ANAPC3 PF12895.7 CBY41825.1 - 2.4 8.4 13.6 14 6.0 0.1 6.7 8 1 1 9 9 7 0 Anaphase-promoting complex, cyclosome, subunit 3 bVLRF1 PF18826.1 CBY41826.1 - 7.5e-33 113.5 0.0 1.7e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 CBY41826.1 - 8.1e-11 41.6 1.8 1.8e-10 40.5 1.8 1.6 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 CBY41826.1 - 1.4e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY41826.1 - 0.00053 20.5 0.0 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY41826.1 - 0.00097 19.4 0.0 0.005 17.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CBY41826.1 - 0.0014 19.2 0.0 0.015 15.9 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 CBY41826.1 - 0.0015 18.9 0.1 0.0046 17.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat DUF3544 PF12064.8 CBY41826.1 - 0.0053 17.1 0.1 0.0053 17.1 0.1 2.1 2 1 1 3 3 3 1 Protein kinase C-binding protein 1 Dimer_Tnp_hAT PF05699.14 CBY41828.1 - 1.3e-09 37.8 0.2 1.8e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HIM1 PF08732.10 CBY41828.1 - 0.0041 16.7 0.1 0.0057 16.2 0.1 1.3 1 1 0 1 1 1 1 HIM1 ADAM_CR_2 PF17771.1 CBY41829.1 - 0.091 13.3 0.6 0.091 13.3 0.6 2.2 3 0 0 3 3 3 0 ADAM cysteine-rich domain Herpes_UL17 PF04559.12 CBY41829.1 - 0.17 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein Gal-3-0_sulfotr PF06990.11 CBY41831.1 - 1.7e-08 33.8 0.0 1.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase EMP24_GP25L PF01105.24 CBY41832.1 - 6.6e-13 49.0 0.0 1.1e-12 48.3 0.0 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Claudin_2 PF13903.6 CBY41833.1 - 0.00013 21.8 12.1 0.01 15.6 13.3 2.8 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 CBY41833.1 - 0.012 15.5 3.3 0.012 15.4 1.5 2.0 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family Nitrate_red_gam PF02665.14 CBY41833.1 - 0.013 15.1 0.7 0.02 14.5 0.7 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SUR7 PF06687.12 CBY41833.1 - 3.3 7.3 11.6 20 4.7 11.6 2.3 1 1 0 1 1 1 0 SUR7/PalI family DUF2613 PF11021.8 CBY41833.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2613) PsbY PF06298.11 CBY41833.1 - 3.5 7.6 7.5 0.65 9.9 0.4 2.4 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) zf-C3HC4_3 PF13920.6 CBY41834.1 - 4.1e-07 29.7 5.0 5.7e-07 29.3 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY41834.1 - 1e-06 28.5 5.7 1.5e-06 27.9 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY41834.1 - 8e-06 25.7 4.4 1.1e-05 25.3 4.4 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY41834.1 - 1.6e-05 24.6 5.9 2.3e-05 24.2 5.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBY41834.1 - 4.3e-05 23.3 3.9 6.6e-05 22.7 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY41834.1 - 0.00013 22.3 5.7 0.00018 21.8 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.14 CBY41834.1 - 0.0017 18.0 3.9 0.0027 17.4 3.9 1.3 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 CBY41834.1 - 0.0044 17.3 2.7 0.0058 16.9 2.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CBY41834.1 - 0.012 15.5 4.3 0.012 15.5 4.3 1.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBY41834.1 - 0.015 15.1 4.5 0.027 14.2 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CBY41834.1 - 0.037 14.1 3.6 0.037 14.1 3.6 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Meiotic_rec114 PF03525.14 CBY41834.1 - 0.29 10.0 0.0 0.3 10.0 0.0 1.0 1 0 0 1 1 1 0 Meiotic recombination protein rec114 zf-C3HC4_5 PF17121.5 CBY41834.1 - 1.1 9.2 10.0 1.5 8.7 7.6 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhoPQ_related PF10142.9 CBY41835.1 - 3.5e-61 206.9 0.5 4.2e-61 206.6 0.5 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Peptidase_S15 PF02129.18 CBY41835.1 - 0.0028 17.3 0.2 0.0048 16.5 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FlgT_M PF16539.5 CBY41835.1 - 0.018 15.2 0.2 0.029 14.5 0.2 1.2 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain Ank_2 PF12796.7 CBY41836.1 - 5.3e-45 151.9 9.1 2e-13 50.7 0.0 5.4 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY41836.1 - 1.5e-40 137.1 5.9 3.2e-10 40.3 0.1 8.4 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY41836.1 - 3.4e-31 106.9 4.9 2.3e-10 40.5 0.1 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY41836.1 - 3.8e-31 103.6 3.8 0.00011 22.3 0.0 9.1 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.30 CBY41836.1 - 2.8e-30 103.4 5.3 1.6e-06 28.3 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Homeodomain PF00046.29 CBY41838.1 - 1.4e-21 76.1 3.3 1.4e-21 76.1 3.3 2.3 3 0 0 3 3 3 1 Homeodomain Trypsin PF00089.26 CBY41841.1 - 1.3e-52 178.8 2.8 1.2e-26 94.0 1.1 2.4 2 0 0 2 2 2 2 Trypsin Kringle PF00051.18 CBY41841.1 - 6.3e-23 80.9 3.5 6.3e-23 80.9 3.5 3.1 3 0 0 3 3 3 1 Kringle domain DUF1986 PF09342.11 CBY41841.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) LRR_4 PF12799.7 CBY41843.1 - 0.00058 20.2 15.2 0.0099 16.3 6.7 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) NETI PF14044.6 CBY41843.1 - 0.2 11.4 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 NETI protein Trypsin PF00089.26 CBY41845.1 - 3.7e-55 187.1 0.3 3.7e-55 187.1 0.3 1.8 2 0 0 2 2 2 1 Trypsin Pro_isomerase PF00160.21 CBY41845.1 - 3.5e-12 46.9 0.0 9.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trypsin_2 PF13365.6 CBY41845.1 - 2.2e-06 28.7 0.0 4.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain LRR_4 PF12799.7 CBY41848.1 - 7.8e-10 38.9 7.2 0.0013 19.1 1.1 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY41848.1 - 3.1e-07 30.0 8.6 0.001 18.8 4.2 3.9 3 1 1 4 4 4 3 Leucine rich repeat RE_CfrBI PF09516.10 CBY41848.1 - 0.1 12.0 1.4 0.16 11.3 1.4 1.3 1 0 0 1 1 1 0 CfrBI restriction endonuclease LRR_1 PF00560.33 CBY41848.1 - 1.5 9.6 9.1 34 5.5 0.0 5.2 7 0 0 7 7 7 0 Leucine Rich Repeat Carn_acyltransf PF00755.20 CBY41849.1 - 4.4e-54 184.1 0.0 1.5e-39 136.1 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase CarbpepA_inh PF02977.15 CBY41850.1 - 0.19 11.5 3.9 3.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor DnaJ_CXXCXGXG PF00684.19 CBY41851.1 - 0.016 15.6 12.6 3 8.3 13.1 3.0 1 1 0 1 1 1 0 DnaJ central domain VWA_N2 PF16164.5 CBY41851.1 - 2.8 8.1 9.5 0.29 11.3 2.0 2.3 2 0 0 2 2 2 0 VWA N-terminal DUF218 PF02698.17 CBY41853.1 - 0.078 13.0 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 DUF218 domain Tmemb_9 PF05434.11 CBY41855.1 - 2.5e-20 72.9 2.3 2.5e-20 72.9 2.3 2.0 2 1 0 2 2 2 1 TMEM9 MCLC PF05934.11 CBY41855.1 - 0.056 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RRM_1 PF00076.22 CBY41856.1 - 1.1e-12 47.6 2.7 4.7e-10 39.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBY41856.1 - 0.024 14.5 0.6 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF148 PF02520.17 CBY41856.1 - 0.25 11.5 4.0 0.21 11.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Lectin_C PF00059.21 CBY41857.1 - 0.00043 21.0 0.7 0.0064 17.2 0.5 2.4 2 0 0 2 2 2 1 Lectin C-type domain Peptidase_S9 PF00326.21 CBY41858.1 - 9.7e-20 70.9 0.2 1.6e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family fn3 PF00041.21 CBY41861.1 - 0.00035 20.9 0.0 1.5 9.2 0.0 2.6 2 1 0 2 2 2 2 Fibronectin type III domain ThiF PF00899.21 CBY41862.1 - 1.1e-49 169.0 0.0 1.2e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 CBY41862.1 - 0.00053 20.4 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBY41862.1 - 0.0023 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 CBY41862.1 - 0.027 14.4 0.1 0.045 13.7 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 CBY41862.1 - 0.15 12.6 0.2 0.36 11.4 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CpXC PF14353.6 CBY41864.1 - 0.0053 16.8 2.3 0.053 13.6 1.4 2.1 2 0 0 2 2 2 1 CpXC protein 7tm_2 PF00002.24 CBY41865.1 - 2.3e-08 33.6 1.6 2.7e-08 33.4 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Rad1 PF02144.16 CBY41865.1 - 0.14 11.2 0.2 0.19 10.7 0.2 1.0 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 IHHNV_capsid PF16530.5 CBY41867.1 - 0.037 13.1 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid EPO_TPO PF00758.18 CBY41868.1 - 0.21 11.6 0.1 0.3 11.1 0.1 1.1 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin ATP-synt_Eps PF04627.13 CBY41869.1 - 0.1 12.6 3.1 5.8 7.0 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain Cu_amine_oxid PF01179.20 CBY41869.1 - 0.11 11.4 0.5 0.24 10.3 0.5 1.5 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Pkinase PF00069.25 CBY41870.1 - 2e-11 43.8 0.1 5.6e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41870.1 - 1.3e-08 34.5 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY41870.1 - 0.13 12.4 4.9 2.1 8.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) HECT PF00632.25 CBY41871.1 - 1.8e-13 50.7 0.1 1.8e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) B56 PF01603.20 CBY41872.1 - 3.4e-40 138.3 0.0 3.9e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 CBY41873.1 - 4e-48 164.4 9.5 4.5e-48 164.2 9.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CBY41873.1 - 0.085 12.8 2.0 2.9 7.8 2.0 2.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal APP_amyloid PF10515.9 CBY41876.1 - 2e-12 47.4 0.1 3.4e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Beta-amyloid precursor protein C-terminus APP_Cu_bd PF12924.7 CBY41876.1 - 3.3e-09 37.3 1.3 4.9e-09 36.8 1.3 1.3 1 0 0 1 1 1 1 Copper-binding of amyloid precursor, CuBD TMEM51 PF15345.6 CBY41876.1 - 0.0015 18.5 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Amnionless PF14828.6 CBY41876.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless CcmD PF04995.14 CBY41876.1 - 4.5 7.4 7.9 13 6.0 7.9 1.8 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Homeodomain PF00046.29 CBY41877.1 - 1.7e-20 72.6 3.3 1.7e-20 72.6 3.3 2.7 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 CBY41877.1 - 0.058 13.3 1.5 0.073 13.0 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Phospholip_A2_1 PF00068.19 CBY41881.1 - 3.1e-13 50.2 4.6 5.1e-13 49.5 4.6 1.3 1 0 0 1 1 1 1 Phospholipase A2 RIFIN PF02009.16 CBY41881.1 - 0.18 11.7 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Rifin AMP-binding PF00501.28 CBY41882.1 - 3.2e-93 312.6 0.0 4.3e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mtc PF03820.17 CBY41883.1 - 2.3e-90 302.8 0.0 2.5e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Glyco_transf_8 PF01501.20 CBY41884.1 - 4.6e-09 36.2 0.2 5.8e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CBY41884.1 - 0.025 13.9 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Gla PF00594.20 CBY41886.1 - 5.2e-11 42.6 3.9 1e-10 41.6 3.9 1.5 1 0 0 1 1 1 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF4550 PF15084.6 CBY41886.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) SesA PF17107.5 CBY41886.1 - 0.1 12.8 0.2 0.18 12.0 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CSN8_PSD8_EIF3K PF10075.9 CBY41887.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family WAC_Acf1_DNA_bd PF10537.9 CBY41887.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.7 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal SAC3_GANP PF03399.16 CBY41887.1 - 0.071 12.5 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 SAC3/GANP family Lung_7-TM_R PF06814.13 CBY41888.1 - 1e-47 162.9 12.7 1.2e-47 162.6 12.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor SPT6_acidic PF14632.6 CBY41888.1 - 0.00067 20.2 1.5 0.0011 19.5 1.5 1.3 1 0 0 1 1 1 1 Acidic N-terminal SPT6 FtsH_ext PF06480.15 CBY41888.1 - 0.16 12.3 0.5 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 FtsH Extracellular Rab5ip PF07019.12 CBY41888.1 - 0.34 11.5 2.8 0.2 12.3 0.4 1.9 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) DUF3671 PF12420.8 CBY41888.1 - 0.4 10.8 6.2 0.13 12.3 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF3810 PF12725.7 CBY41888.1 - 2.4 7.4 5.9 1.5 8.1 4.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Pput2613-deam PF14427.6 CBY41889.1 - 0.018 14.9 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Pput_2613-like deaminase ArsR PF09824.9 CBY41889.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator DUF3364 PF11844.8 CBY41890.1 - 0.045 14.0 0.4 0.051 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) TIG PF01833.24 CBY41891.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 IPT/TIG domain DUF4107 PF13389.6 CBY41892.1 - 0.076 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) RhoGEF PF00621.20 CBY41893.1 - 7.2e-06 26.4 0.1 1e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain Phospholip_A2_1 PF00068.19 CBY41895.1 - 9e-19 68.0 6.7 9e-19 68.0 6.7 1.7 2 1 0 2 2 2 1 Phospholipase A2 Pkinase PF00069.25 CBY41896.1 - 1.6e-09 37.5 0.1 2.3e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41896.1 - 4.4e-08 32.7 0.0 5.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase I-set PF07679.16 CBY41897.1 - 1.6e-69 230.0 0.1 2e-20 72.6 0.0 4.0 4 0 0 4 4 4 4 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY41897.1 - 3e-48 162.3 0.1 2.5e-15 56.8 0.0 4.1 4 0 0 4 4 4 4 Immunoglobulin domain Ig_2 PF13895.6 CBY41897.1 - 1.1e-31 109.0 0.2 1.4e-13 51.0 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain ig PF00047.25 CBY41897.1 - 2.1e-26 91.9 0.0 3.8e-09 36.6 0.0 4.1 4 0 0 4 4 4 3 Immunoglobulin domain V-set PF07686.17 CBY41897.1 - 4.5e-15 55.8 1.3 5.1e-05 23.4 0.0 6.5 4 3 0 4 4 4 2 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY41897.1 - 3.4e-11 43.1 0.2 0.013 15.5 0.0 3.7 4 0 0 4 4 4 3 CD80-like C2-set immunoglobulin domain C1-set PF07654.15 CBY41897.1 - 1.3e-08 35.1 0.0 2.1 8.8 0.0 4.4 4 0 0 4 4 4 3 Immunoglobulin C1-set domain BiPBP_C PF06832.12 CBY41897.1 - 3.3e-07 30.3 0.0 0.47 10.5 0.0 3.5 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Ig_4 PF16680.5 CBY41897.1 - 2.9e-06 27.5 0.5 0.39 11.0 0.1 4.5 4 2 0 4 4 4 2 T-cell surface glycoprotein CD3 delta chain Izumo-Ig PF16706.5 CBY41897.1 - 4.6e-06 26.6 0.0 0.17 12.0 0.0 4.0 3 1 1 4 4 4 2 Izumo-like Immunoglobulin domain Ig_5 PF16681.5 CBY41897.1 - 5.3e-06 26.8 0.3 0.32 11.4 0.0 4.9 4 2 0 4 4 4 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Adeno_E3_CR1 PF02440.15 CBY41897.1 - 0.00014 21.6 0.0 0.29 10.9 0.1 3.6 3 1 0 3 3 3 1 Adenovirus E3 region protein CR1 Ig_6 PF18452.1 CBY41897.1 - 0.0021 17.6 0.4 4.2 7.0 0.1 3.4 3 0 0 3 3 3 1 Immunoglobulin domain Phospholip_A2_1 PF00068.19 CBY41898.1 - 2.4e-17 63.4 6.6 2.8e-17 63.2 6.6 1.1 1 0 0 1 1 1 1 Phospholipase A2 MAM PF00629.23 CBY41899.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 MAM domain, meprin/A5/mu RT_RNaseH_2 PF17919.1 CBY41900.1 - 2.3e-26 91.7 0.0 1e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY41900.1 - 2.4e-21 76.0 0.0 5.5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CBY41900.1 - 9.3e-15 54.7 0.0 2.1e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CBY41900.1 - 9.7e-08 32.2 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY41900.1 - 0.00018 21.6 0.4 0.00043 20.3 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_3 PF13358.6 CBY41900.1 - 0.01 15.6 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 DDE superfamily endonuclease Autoind_bind PF03472.15 CBY41900.1 - 0.033 13.7 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 Autoinducer binding domain gag_pre-integrs PF13976.6 CBY41900.1 - 0.23 11.3 2.0 0.65 9.9 2.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain Sad1_UNC PF07738.13 CBY41901.1 - 2.1e-30 105.4 0.0 3.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Phospholip_A2_1 PF00068.19 CBY41903.1 - 2.4e-17 63.4 9.6 2.4e-17 63.4 9.6 1.7 2 0 0 2 2 2 1 Phospholipase A2 Cupin_8 PF13621.6 CBY41905.1 - 0.0055 16.5 0.0 0.0073 16.0 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain PS_Dcarbxylase PF02666.15 CBY41906.1 - 1.6e-12 47.4 0.0 1.6e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 CBY41906.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.7 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 CBY41906.1 - 0.06 13.6 0.0 0.68 10.2 0.0 2.0 1 1 1 2 2 2 0 Peptidase family M23 Protamine_P2 PF00841.19 CBY41907.1 - 0.014 15.9 5.4 0.015 15.8 5.4 1.1 1 0 0 1 1 1 0 Sperm histone P2 TPR_MLP1_2 PF07926.12 CBY41908.1 - 0.0018 18.4 7.0 0.011 15.9 3.6 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF5309 PF17236.2 CBY41908.1 - 0.0085 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5309) Syntaxin-6_N PF09177.11 CBY41908.1 - 0.028 15.0 5.0 3.1 8.4 0.1 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CBY41908.1 - 0.029 13.3 8.5 0.061 12.2 0.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 CBY41908.1 - 0.24 11.6 8.8 0.99 9.7 0.1 3.0 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF4407 PF14362.6 CBY41908.1 - 0.24 10.7 4.5 1 8.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBY41908.1 - 0.28 11.3 8.4 1.4 9.1 2.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 CBY41908.1 - 0.65 10.2 7.9 0.49 10.6 0.7 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein She9_MDM33 PF05546.11 CBY41908.1 - 1.1 9.1 5.9 0.38 10.5 0.3 2.1 1 1 1 2 2 2 0 She9 / Mdm33 family FliD_N PF02465.18 CBY41908.1 - 1.5 9.6 4.5 2.3 9.0 0.1 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus NYD-SP28_assoc PF14775.6 CBY41908.1 - 2.5 8.2 5.9 10 6.3 0.2 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain KLRAQ PF10205.9 CBY41908.1 - 2.7 8.3 9.7 1.8 8.9 4.3 2.7 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Spc42p PF11544.8 CBY41908.1 - 5.7 7.0 11.8 4.6 7.3 0.5 3.5 3 1 1 4 4 4 0 Spindle pole body component Spc42p Pox_I3 PF04661.12 CBY41910.1 - 0.006 15.7 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus I3 ssDNA-binding protein Hormone_recep PF00104.30 CBY41910.1 - 0.017 14.7 0.9 0.039 13.5 0.9 1.8 1 1 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF3865 PF12981.7 CBY41910.1 - 0.038 13.9 0.3 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) PH PF00169.29 CBY41911.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 CBY41912.1 - 0.0022 18.8 1.1 1.8 9.6 0.2 3.2 4 1 0 4 4 4 2 WD domain, G-beta repeat ThiF PF00899.21 CBY41913.1 - 9.9e-30 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF3926 PF13080.6 CBY41915.1 - 1.5 8.8 6.2 8.5 6.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) PseudoU_synth_1 PF01416.20 CBY41917.1 - 1.2e-29 103.0 0.0 3.3e-28 98.3 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase GTP_EFTU PF00009.27 CBY41918.1 - 1.1e-61 207.7 0.0 1.7e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBY41918.1 - 4e-26 90.9 0.0 8.9e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CBY41918.1 - 1.3e-24 86.3 0.0 3e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CBY41918.1 - 8.9e-17 60.9 0.0 2.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBY41918.1 - 2.5e-11 43.8 0.0 5.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBY41918.1 - 0.00057 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBY41918.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBY41918.1 - 0.0068 16.0 0.0 0.022 14.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CBY41918.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 CBY41918.1 - 0.017 15.1 0.1 0.19 11.6 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Amidohydro_1 PF01979.20 CBY41918.1 - 0.023 14.0 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family SRPRB PF09439.10 CBY41918.1 - 0.11 12.0 0.0 0.58 9.6 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit SMP_LBD PF17047.5 CBY41919.1 - 1e-06 28.3 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 CBY41919.1 - 0.0056 15.8 1.4 0.011 14.8 1.4 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Thyroglobulin_1 PF00086.18 CBY41920.1 - 1e-15 57.1 9.5 5.2e-09 35.6 1.1 4.2 3 0 0 3 3 3 2 Thyroglobulin type-1 repeat SRCR PF00530.18 CBY41920.1 - 1.5e-14 54.3 1.3 8.9e-14 51.8 0.0 3.1 3 0 0 3 3 3 1 Scavenger receptor cysteine-rich domain TIL PF01826.17 CBY41920.1 - 3.5e-08 33.6 35.6 4.3e-06 26.9 12.2 8.5 7 3 1 8 8 8 2 Trypsin Inhibitor like cysteine rich domain ShK PF01549.24 CBY41920.1 - 0.00027 21.4 63.8 0.0028 18.1 5.2 7.1 6 0 0 6 6 6 4 ShK domain-like SRCR_2 PF15494.6 CBY41920.1 - 0.0049 17.4 0.0 0.0049 17.4 0.0 2.5 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain UQ_con PF00179.26 CBY41921.1 - 0.0023 17.6 0.2 0.0035 17.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY41921.1 - 0.13 12.1 0.3 0.28 11.1 0.2 1.6 1 1 1 2 2 2 0 UEV domain UQ_con PF00179.26 CBY41922.1 - 0.0069 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBY41922.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 RWD domain UQ_con PF00179.26 CBY41923.1 - 2.5e-09 36.9 0.9 4.1e-09 36.2 0.9 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBY41923.1 - 0.018 14.9 0.2 0.087 12.7 0.1 2.0 2 0 0 2 2 2 0 UEV domain gp45-slide_C PF09116.10 CBY41923.1 - 0.026 14.6 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal KH_1 PF00013.29 CBY41924.1 - 1.9e-15 56.4 0.0 3.9e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 CBY41924.1 - 0.0039 17.0 0.1 0.0082 16.0 0.1 1.6 1 1 0 1 1 1 1 KH domain KH_4 PF13083.6 CBY41924.1 - 0.033 14.0 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 KH domain Pkinase PF00069.25 CBY41925.1 - 1.6e-71 240.8 0.0 2e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41925.1 - 6.2e-31 107.6 0.1 8e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY41925.1 - 1.7e-08 34.1 0.1 3.2e-08 33.2 0.1 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CBY41925.1 - 7.1e-07 29.1 0.7 0.013 15.1 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBY41925.1 - 3.6e-06 26.0 0.1 8.5e-06 24.8 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBY41925.1 - 7.5e-05 21.8 3.0 0.00021 20.4 3.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY41925.1 - 0.0018 18.2 0.1 0.016 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBY41925.1 - 0.0019 17.6 0.9 0.0053 16.1 0.3 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rep_Org_C PF06926.11 CBY41925.1 - 0.035 14.4 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus Aa_trans PF01490.18 CBY41926.1 - 1e-23 83.8 39.2 1.9e-23 82.8 39.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein CopD PF05425.13 CBY41926.1 - 0.0028 18.0 0.3 0.0028 18.0 0.3 2.6 3 0 0 3 3 3 1 Copper resistance protein D Renin_r PF07850.14 CBY41928.1 - 0.0076 16.8 0.0 0.018 15.6 0.0 1.6 1 1 0 1 1 1 1 Renin receptor-like protein DnaJ PF00226.31 CBY41929.1 - 1.6e-24 85.8 2.8 2.5e-24 85.2 2.8 1.3 1 0 0 1 1 1 1 DnaJ domain Prominin PF05478.11 CBY41929.1 - 0.057 11.4 8.9 0.071 11.1 8.9 1.1 1 0 0 1 1 1 0 Prominin U79_P34 PF03064.16 CBY41929.1 - 0.52 9.6 3.9 0.66 9.3 3.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SHQ1 PF04925.15 CBY41930.1 - 5.7e-10 39.0 0.1 9.1e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 SHQ1 protein EGF_CA PF07645.15 CBY41931.1 - 7.7e-05 22.8 0.6 0.00015 21.9 0.6 1.5 1 0 0 1 1 1 1 Calcium-binding EGF domain DUF237 PF03072.14 CBY41931.1 - 0.0034 17.4 0.0 0.0086 16.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF237) TRM PF02005.16 CBY41932.1 - 7.8e-111 370.9 0.0 1e-110 370.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 CBY41932.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Det1 PF09737.9 CBY41935.1 - 4.6e-57 193.9 4.5 7.4e-57 193.3 4.5 1.3 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 RED_N PF07808.13 CBY41935.1 - 4.4e-25 88.6 6.6 1.1e-24 87.3 6.6 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region PSI_PsaH PF03244.14 CBY41935.1 - 7.4 6.1 5.8 4.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Photosystem I reaction centre subunit VI DRY_EERY PF09750.9 CBY41935.1 - 9 6.6 12.6 25 5.1 0.0 2.9 2 1 0 2 2 2 0 Alternative splicing regulator T7SS_ESX1_EccB PF05108.13 CBY41936.1 - 0.19 10.4 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B 7tm_1 PF00001.21 CBY41937.1 - 5.7e-12 45.5 12.4 5.7e-12 45.5 12.4 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIP PF00230.20 CBY41939.1 - 4.7e-14 52.6 0.1 5e-14 52.6 0.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein TMEM144 PF07857.12 CBY41939.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters SBF_like PF13593.6 CBY41943.1 - 1.7e-34 119.6 7.7 1.9e-34 119.4 7.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CBY41943.1 - 0.0015 18.3 0.3 0.0015 18.3 0.3 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family NnrS PF05940.12 CBY41943.1 - 0.0026 17.2 2.0 0.0039 16.6 2.0 1.4 1 1 0 1 1 1 1 NnrS protein Solute_trans_a PF03619.16 CBY41944.1 - 6.1e-20 71.8 18.1 9.6e-19 67.9 18.1 2.1 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF4973 PF16343.5 CBY41945.1 - 0.071 13.2 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) VWA PF00092.28 CBY41946.1 - 0.0023 18.2 0.0 0.0074 16.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY41946.1 - 0.012 16.3 0.1 0.58 10.8 0.1 2.4 1 1 0 1 1 1 0 von Willebrand factor type A domain TFIIB PF00382.19 CBY41946.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat BING4CT PF08149.11 CBY41949.1 - 2e-29 101.2 0.0 3.8e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 BING4CT (NUC141) domain Nup160 PF11715.8 CBY41949.1 - 0.0082 14.8 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.32 CBY41949.1 - 0.011 16.6 0.1 0.041 14.8 0.2 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBY41949.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TSSC4 PF15264.6 CBY41950.1 - 2.8e-13 50.2 1.9 2.8e-13 50.2 1.9 2.2 1 1 1 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 PPDFL PF15060.6 CBY41950.1 - 0.54 10.8 3.7 0.22 12.0 1.0 1.8 2 1 0 2 2 2 0 Differentiation and proliferation regulator MFS_Mycoplasma PF07672.13 CBY41951.1 - 0.0048 16.2 0.1 0.0053 16.1 0.1 1.1 1 0 0 1 1 1 1 Mycoplasma MFS transporter IF4E PF01652.18 CBY41952.1 - 3.1e-41 140.8 0.5 4e-41 140.5 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E fn3 PF00041.21 CBY41953.1 - 3.3e-11 43.4 0.3 0.0016 18.7 0.0 3.3 2 1 1 3 3 3 2 Fibronectin type III domain I-set PF07679.16 CBY41953.1 - 0.0032 17.5 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF3439 PF11921.8 CBY41953.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) fn3 PF00041.21 CBY41954.1 - 1.7e-95 313.5 0.3 5.3e-16 58.7 0.0 7.3 7 0 0 7 7 7 7 Fibronectin type III domain I-set PF07679.16 CBY41954.1 - 7.5e-29 99.6 0.1 1.5e-13 50.6 0.0 4.0 4 0 0 4 4 4 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY41954.1 - 1.4e-19 70.5 0.2 3.6e-08 33.9 0.0 4.1 4 0 0 4 4 4 2 Immunoglobulin domain ig PF00047.25 CBY41954.1 - 3.8e-13 49.4 0.3 1e-05 25.6 0.0 2.9 3 0 0 3 3 2 2 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY41954.1 - 1.2e-10 41.8 1.4 0.36 11.4 0.0 7.0 6 1 0 6 6 6 3 Purple acid Phosphatase, N-terminal domain Tissue_fac PF01108.17 CBY41954.1 - 3.6e-10 39.7 1.9 0.0094 15.8 0.0 5.0 5 0 0 5 5 5 3 Tissue factor Ig_2 PF13895.6 CBY41954.1 - 1.6e-08 34.7 0.0 0.0045 17.3 0.0 2.7 2 0 0 2 2 2 2 Immunoglobulin domain fn3_4 PF16794.5 CBY41954.1 - 9.5e-07 28.7 0.0 0.18 11.8 0.0 5.3 5 1 0 5 5 5 1 Fibronectin-III type domain fn3_2 PF16893.5 CBY41954.1 - 0.00031 20.8 0.1 6 7.1 0.0 5.1 7 0 0 7 7 7 1 Fibronectin type III domain V-set PF07686.17 CBY41954.1 - 0.00053 20.1 0.4 1.5 9.0 0.1 4.4 3 2 2 5 5 5 1 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY41954.1 - 0.0089 16.1 0.0 0.51 10.5 0.0 2.7 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain Receptor_2B4 PF11465.8 CBY41954.1 - 0.2 11.9 0.5 49 4.2 0.0 4.0 3 1 1 4 4 4 0 Natural killer cell receptor 2B4 COX6B PF02297.17 CBY41955.1 - 9.1e-12 45.0 5.4 1.1e-11 44.8 5.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb LAS2 PF15792.5 CBY41955.1 - 0.062 13.8 0.6 0.53 10.8 0.1 2.0 1 1 1 2 2 2 0 Lung adenoma susceptibility protein 2 CPW_WPC PF09717.10 CBY41955.1 - 0.64 11.0 6.0 0.42 11.6 1.0 2.1 1 1 1 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) RNB PF00773.19 CBY41956.1 - 3.3e-101 338.9 0.0 5e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBY41956.1 - 3e-15 56.0 0.2 1.9e-14 53.4 0.1 2.4 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CBY41956.1 - 0.00063 20.0 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CBY41956.1 - 0.0026 17.9 0.3 0.14 12.3 0.1 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 CBY41956.1 - 0.01 15.6 0.1 0.025 14.3 0.1 1.7 1 1 0 1 1 1 0 Rrp44-like cold shock domain TB2_DP1_HVA22 PF03134.19 CBY41958.1 - 1.9e-29 101.4 5.6 3.3e-29 100.6 5.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TMEM220 PF15071.6 CBY41958.1 - 5.3 7.9 6.9 58 4.5 5.8 2.7 2 1 0 2 2 2 0 Transmembrane family 220, helix SMC_N PF02463.19 CBY41959.1 - 0.035 13.6 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Polysacc_deac_3 PF15421.6 CBY41959.1 - 0.059 11.9 0.0 0.063 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF3050 PF11251.8 CBY41960.1 - 1.3e-87 293.4 0.1 1.6e-87 293.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) TarH PF02203.15 CBY41961.1 - 0.016 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue bVLRF1 PF18826.1 CBY41961.1 - 0.097 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Pkinase PF00069.25 CBY41962.1 - 1e-40 139.8 0.0 1.5e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41962.1 - 2.6e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_10 PF13460.6 CBY41963.1 - 5e-06 26.5 0.0 9.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CBY41963.1 - 0.00058 20.3 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ank_5 PF13857.6 CBY41964.1 - 1.2e-05 25.4 0.4 0.0093 16.3 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY41964.1 - 0.00029 21.0 0.0 3.7 8.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 CBY41964.1 - 0.0023 18.5 0.3 0.04 14.5 0.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY41964.1 - 0.0026 18.3 1.1 3.6 8.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY41964.1 - 0.021 15.3 0.0 0.63 10.6 0.0 3.0 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 CBY41965.1 - 4.2e-05 23.7 0.0 0.039 14.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY41965.1 - 0.0029 18.0 0.0 0.37 11.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CBY41965.1 - 0.01 16.4 0.0 1.3 9.6 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DPPIV_N PF00930.21 CBY41966.1 - 6.5e-31 107.4 4.0 1.1e-30 106.6 4.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PIG-S PF10510.9 CBY41967.1 - 1.2e-48 166.2 8.6 1.3e-43 149.6 2.9 2.8 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein HMA PF00403.26 CBY41968.1 - 3.1e-06 27.6 0.5 4.6e-06 27.0 0.5 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain TFIIS_C PF01096.18 CBY41968.1 - 0.082 12.8 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CBY41968.1 - 0.15 11.8 1.6 0.16 11.7 0.0 1.8 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Prefoldin PF02996.17 CBY41969.1 - 1.2e-10 41.3 1.0 1.2e-10 41.3 1.0 2.5 2 1 1 3 3 3 1 Prefoldin subunit DUF621 PF04789.15 CBY41969.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Patched PF02460.18 CBY41969.1 - 0.36 8.8 1.6 0.55 8.2 1.6 1.3 1 0 0 1 1 1 0 Patched family CoA_transf_3 PF02515.17 CBY41969.1 - 1.5 7.9 5.3 14 4.6 0.0 2.4 1 1 1 2 2 2 0 CoA-transferase family III DUF3926 PF13080.6 CBY41969.1 - 2.4 8.2 6.0 2.2 8.3 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) Membralin PF09746.9 CBY41969.1 - 9.1 5.2 8.4 14 4.6 8.4 1.2 1 0 0 1 1 1 0 Tumour-associated protein BTB PF00651.31 CBY41970.1 - 2e-05 24.8 0.3 7.7e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain MATH PF00917.26 CBY41970.1 - 0.0021 18.2 0.1 0.007 16.5 0.0 1.9 2 0 0 2 2 2 1 MATH domain CAP_N PF01213.19 CBY41971.1 - 0.95 8.9 5.4 1.4 8.4 5.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Syndecan PF01034.20 CBY41974.1 - 3.7e-08 33.2 0.3 4.5e-08 32.9 0.3 1.1 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 CBY41974.1 - 0.0024 18.1 0.0 0.0028 17.9 0.0 1.1 1 0 0 1 1 1 1 Glycophorin A CbtA PF09490.10 CBY41974.1 - 0.065 13.0 0.4 0.084 12.6 0.4 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Podoplanin PF05808.11 CBY41974.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Podoplanin Protocadherin PF08374.11 CBY41974.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Septin PF00735.18 CBY41975.1 - 2.9e-115 384.4 0.0 2.9e-115 384.4 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CBY41975.1 - 1.1e-06 28.7 0.1 3.8e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBY41975.1 - 2.4e-05 24.3 1.3 9.9e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CBY41975.1 - 0.00025 20.5 0.0 0.00025 20.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CBY41975.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 CBY41975.1 - 0.017 15.5 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 CBY41975.1 - 0.021 14.3 4.2 0.37 10.3 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CBY41975.1 - 0.025 14.8 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBY41975.1 - 0.042 14.1 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CBY41975.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 CBY41975.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 CBY41975.1 - 1.2 9.2 14.1 2 8.5 0.0 3.6 2 2 1 3 3 3 0 Dynamin family Prominin PF05478.11 CBY41975.1 - 2.9 5.7 10.6 3.6 5.4 10.6 1.1 1 0 0 1 1 1 0 Prominin PKD_channel PF08016.12 CBY41976.1 - 7.6e-77 258.8 5.8 1e-76 258.4 5.8 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBY41976.1 - 3.9e-17 62.3 27.4 3.9e-17 62.3 27.4 1.6 2 0 0 2 2 2 1 Ion transport protein ADH_zinc_N_2 PF13602.6 CBY41977.1 - 2.7e-08 35.0 0.0 8e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CBY41977.1 - 0.0029 18.0 0.1 0.0056 17.1 0.1 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 CBY41977.1 - 0.015 14.8 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase CbiD PF01888.17 CBY41977.1 - 0.072 12.4 1.8 0.74 9.1 2.2 2.1 1 1 1 2 2 2 0 CbiD THF_DHG_CYH_C PF02882.19 CBY41977.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 CBY41977.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CBY41977.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldl_recept_a PF00057.18 CBY41979.1 - 9.2e-08 32.2 19.2 1.1e-06 28.7 5.7 2.7 3 0 0 3 3 3 2 Low-density lipoprotein receptor domain class A SIT PF15330.6 CBY41979.1 - 0.0071 16.8 0.1 0.016 15.6 0.0 1.6 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT PRKCSH-like PF12999.7 CBY41979.1 - 0.018 14.9 4.1 0.039 13.7 4.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like MLANA PF14991.6 CBY41979.1 - 0.032 14.5 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A Adeno_E3_CR2 PF02439.15 CBY41979.1 - 0.088 12.6 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IRK_C PF17655.1 CBY41980.1 - 3.4e-67 225.4 0.0 4.9e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Inward rectifier potassium channel C-terminal domain XK-related PF09815.9 CBY41980.1 - 0.00094 18.3 0.2 0.0012 17.9 0.2 1.2 1 0 0 1 1 1 1 XK-related protein Dimer_Tnp_hAT PF05699.14 CBY41982.1 - 1.4e-07 31.2 0.1 3.7e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase_Tyr PF07714.17 CBY41983.1 - 1.7e-10 40.7 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY41983.1 - 5e-06 26.1 0.0 6.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain 7tm_1 PF00001.21 CBY41984.1 - 1e-08 34.9 3.7 1.4e-08 34.4 3.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TAS2R PF05296.13 CBY41984.1 - 0.00026 20.2 1.5 0.00032 19.9 1.5 1.1 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) PRA1 PF03208.19 CBY41984.1 - 0.23 11.1 4.4 0.38 10.4 4.4 1.3 1 0 0 1 1 1 0 PRA1 family protein DUF3671 PF12420.8 CBY41984.1 - 7.9 6.6 7.2 26 4.9 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function Ion_trans PF00520.31 CBY41985.1 - 1.4e-25 89.9 13.3 2.4e-25 89.2 13.3 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY41985.1 - 2e-14 53.1 12.4 9.7e-14 50.9 12.4 1.9 1 1 0 1 1 1 1 Polycystin cation channel TRP_2 PF08344.11 CBY41985.1 - 0.055 13.7 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Transient receptor ion channel II PBC PF03792.13 CBY41985.1 - 0.16 11.7 0.2 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 PBC domain AA_permease_2 PF13520.6 CBY41986.1 - 1.1e-05 24.4 1.7 1.2e-05 24.4 1.7 1.0 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.29 CBY41987.1 - 3.7e-30 105.3 0.3 4.2e-30 105.1 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY41987.1 - 8.8e-07 28.8 1.5 2.9e-05 23.8 1.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CBY41987.1 - 0.0033 17.2 0.7 0.005 16.6 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-ribbon_3 PF13248.6 CBY41987.1 - 0.019 14.4 4.4 0.26 10.8 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CBY41987.1 - 0.061 13.2 1.6 2.9 7.9 0.5 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 CBY41987.1 - 0.086 13.0 2.8 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CBY41987.1 - 0.12 12.4 1.1 18 5.4 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 CBY41987.1 - 0.17 11.9 1.1 4.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.17 CBY41987.1 - 0.19 11.5 3.3 2.6 7.8 0.5 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 PHD PF00628.29 CBY41987.1 - 0.34 10.8 2.9 0.38 10.7 0.9 2.0 2 0 0 2 2 2 0 PHD-finger OrfB_Zn_ribbon PF07282.11 CBY41987.1 - 0.36 10.8 1.8 9.1 6.3 0.2 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RING_7 PF02591.15 CBY41987.1 - 0.43 10.8 1.6 9.5 6.5 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain Rubredoxin PF00301.20 CBY41987.1 - 0.66 10.0 3.3 2.7 8.1 0.6 2.5 2 0 0 2 2 2 0 Rubredoxin DUF35_N PF12172.8 CBY41987.1 - 2.1 8.3 9.2 20 5.2 2.3 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_4 PF13717.6 CBY41987.1 - 2.7 8.0 4.6 3 7.8 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Sulfatase PF00884.23 CBY41988.1 - 2.8e-49 168.2 0.0 1.2e-47 162.8 0.0 2.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CBY41988.1 - 2.1e-05 24.3 0.0 0.047 13.3 0.0 3.3 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CBY41988.1 - 0.00036 19.3 0.0 0.00075 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 CBY41988.1 - 0.0093 16.2 1.7 0.015 15.5 0.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) PBP1_TM PF14812.6 CBY41989.1 - 0.058 13.8 0.9 0.058 13.8 0.9 2.4 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thyroglobulin_1 PF00086.18 CBY41990.1 - 0.0053 16.4 0.0 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Thyroglobulin type-1 repeat Pkinase PF00069.25 CBY41991.1 - 1e-63 215.2 0.0 1.4e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY41991.1 - 1.4e-28 99.9 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY41991.1 - 5.7e-09 35.7 0.0 9.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBY41991.1 - 0.00057 19.3 0.8 0.0016 17.9 0.8 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBY41991.1 - 0.00086 18.9 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Ribos_L4_asso_C PF14374.6 CBY41991.1 - 0.0043 17.1 0.3 0.0043 17.1 0.3 2.4 4 0 0 4 4 4 1 60S ribosomal protein L4 C-terminal domain FTA2 PF13095.6 CBY41991.1 - 0.046 13.3 0.3 0.089 12.4 0.0 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBY41991.1 - 0.093 12.6 0.3 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family SMK-1 PF04802.15 CBY41992.1 - 9.5e-08 32.1 0.1 1.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 CBY41992.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 WH1 domain Ran_BP1 PF00638.18 CBY41992.1 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DCP1 PF06058.13 CBY41992.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Dcp1-like decapping family Rap_GAP PF02145.15 CBY41994.1 - 6.3e-19 68.3 0.0 9.8e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Sulfotransfer_1 PF00685.27 CBY41996.1 - 1.5e-09 37.7 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY41996.1 - 9.4e-09 36.0 0.0 1.6e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family T4_Rnl2_C PF18043.1 CBY41996.1 - 0.13 12.5 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal PatG_C PF18065.1 CBY41998.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 PatG C-terminal DUF3671 PF12420.8 CBY41998.1 - 0.24 11.5 3.3 1.9 8.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function COX1 PF00115.20 CBY41998.1 - 0.42 9.4 5.2 6.3 5.5 4.9 2.0 1 1 1 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Lectin_C PF00059.21 CBY41999.1 - 6.9e-07 30.0 11.1 0.034 14.9 2.8 3.9 2 2 0 2 2 2 2 Lectin C-type domain Xlink PF00193.17 CBY41999.1 - 0.078 13.4 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Extracellular link domain SpecificRecomb PF10136.9 CBY42000.1 - 0.12 10.7 1.2 0.17 10.1 1.0 1.3 1 1 0 1 1 1 0 Site-specific recombinase zf-C3HC4_3 PF13920.6 CBY42002.1 - 1.2e-12 47.4 9.0 1.4e-12 47.3 9.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY42002.1 - 1.2e-05 25.1 10.6 1.5e-05 24.7 10.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBY42002.1 - 0.002 18.1 10.8 0.0028 17.6 10.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 CBY42002.1 - 0.028 14.7 1.2 0.028 14.7 1.2 2.2 2 0 0 2 2 2 0 zinc-ribbon Auto_anti-p27 PF06677.12 CBY42002.1 - 0.5 10.6 0.3 0.5 10.6 0.3 2.8 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_4 PF14570.6 CBY42002.1 - 0.7 9.7 8.8 2.9 7.7 8.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Tetraspanin PF00335.20 CBY42003.1 - 4.3e-25 88.8 12.1 6.2e-25 88.3 12.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Vma12 PF11712.8 CBY42003.1 - 0.56 10.3 5.4 0.33 11.0 0.5 2.5 1 1 2 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Profilin PF00235.19 CBY42004.1 - 1.9e-14 54.0 0.0 2.1e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Peptidase_M2 PF01401.18 CBY42005.1 - 2.2e-33 115.7 0.0 2.5e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Angiotensin-converting enzyme sCache_2 PF17200.4 CBY42005.1 - 0.21 11.4 0.1 0.54 10.1 0.1 1.7 2 0 0 2 2 2 0 Single Cache domain 2 Kazal_2 PF07648.15 CBY42006.1 - 4.3e-12 46.0 12.5 2e-09 37.4 6.2 2.6 2 1 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY42006.1 - 9.4e-06 25.6 5.6 9.4e-06 25.6 5.6 2.4 2 1 0 2 2 2 1 Kazal-type serine protease inhibitor domain Tat PF00539.18 CBY42006.1 - 0.3 11.3 7.6 2.3 8.5 0.7 2.5 1 1 1 2 2 2 0 Transactivating regulatory protein (Tat) TetR_C_23 PF17931.1 CBY42007.1 - 0.073 13.2 3.0 0.096 12.8 0.8 2.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain LON_substr_bdg PF02190.16 CBY42007.1 - 0.27 11.1 2.3 0.58 10.0 2.3 1.6 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Kazal_2 PF07648.15 CBY42008.1 - 8.1e-09 35.5 1.8 1.5e-08 34.6 1.8 1.6 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY42008.1 - 3.2e-06 27.0 2.2 3.2e-06 27.0 2.2 1.5 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Glyco_hydro_35 PF01301.19 CBY42009.1 - 4.5e-08 33.1 0.0 5.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CBY42011.1 - 0.001 19.6 0.1 0.0011 19.5 0.1 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain DUF536 PF04394.14 CBY42013.1 - 0.032 14.1 3.2 5.8 6.9 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 LMSTEN PF07988.12 CBY42013.1 - 0.35 10.4 4.1 0.3 10.6 2.0 2.0 2 0 0 2 2 2 0 LMSTEN motif AKAP7_NLS PF10469.9 CBY42013.1 - 0.36 10.7 6.8 0.25 11.2 3.4 2.2 1 1 1 2 2 2 0 AKAP7 2'5' RNA ligase-like domain Phlebovirus_NSM PF07246.11 CBY42013.1 - 0.55 9.6 15.6 0.44 9.9 5.5 2.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M zf-rbx1 PF12678.7 CBY42014.1 - 1.9e-11 44.0 7.9 4e-11 43.0 7.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBY42014.1 - 6.8e-10 39.1 9.7 6.8e-10 39.1 9.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY42014.1 - 9.6e-08 31.7 8.4 9.6e-08 31.7 8.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY42014.1 - 5.7e-07 29.3 8.0 5.7e-07 29.3 8.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY42014.1 - 7.4e-07 28.8 6.3 1.8e-06 27.6 6.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 CBY42014.1 - 3.2e-06 27.0 9.2 9.9e-06 25.4 6.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY42014.1 - 1.4e-05 25.0 6.5 2.8e-05 24.1 6.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBY42014.1 - 0.00035 20.5 7.8 0.0015 18.5 7.8 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY42014.1 - 0.0022 17.8 9.1 0.0022 17.8 9.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 CBY42014.1 - 0.019 15.1 2.2 0.033 14.4 2.2 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 CBY42014.1 - 0.022 14.3 8.2 0.04 13.5 8.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 CBY42014.1 - 0.13 12.4 8.5 0.32 11.2 8.5 1.7 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CBY42014.1 - 0.53 10.1 5.0 0.59 10.0 3.5 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 CBY42014.1 - 3.6 7.5 15.9 0.2 11.5 9.2 2.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Glyco_transf_43 PF03360.16 CBY42016.1 - 2.1e-64 217.1 0.0 2.6e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 CCDC92 PF14916.6 CBY42016.1 - 0.017 14.8 0.8 0.095 12.5 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function HALZ PF02183.18 CBY42016.1 - 0.066 13.4 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper MIP PF00230.20 CBY42018.1 - 4.8e-43 147.5 10.2 6.5e-43 147.1 10.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Phage_holin_5_2 PF16079.5 CBY42018.1 - 0.15 12.4 1.6 1.3 9.4 0.0 2.9 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V zf-met PF12874.7 CBY42020.1 - 2.3e-05 24.6 1.2 4.9e-05 23.6 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY42020.1 - 0.00032 20.9 2.8 0.00066 19.9 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding MSA-2c PF12238.8 CBY42020.1 - 0.0026 17.8 1.0 0.0036 17.4 1.0 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c zf-C2H2 PF00096.26 CBY42020.1 - 0.0059 17.0 0.5 0.01 16.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CBY42020.1 - 0.0075 16.6 1.2 0.0075 16.6 1.2 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NES_C_h PF18208.1 CBY42020.1 - 0.027 14.8 2.9 0.032 14.5 2.9 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain zf-C2H2_4 PF13894.6 CBY42020.1 - 0.074 13.9 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4337 PF14235.6 CBY42020.1 - 5.6 7.0 6.1 6.5 6.8 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_E PF05680.12 CBY42020.1 - 5.9 7.3 8.5 7.7 6.9 8.2 1.4 1 1 0 1 1 1 0 ATP synthase E chain Thioredoxin PF00085.20 CBY42021.1 - 1.5e-20 73.0 0.0 2.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 CBY42021.1 - 4.1e-11 42.9 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 CBY42021.1 - 4.2e-05 24.0 0.0 0.00026 21.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CBY42021.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBY42021.1 - 0.017 15.4 0.0 0.058 13.7 0.0 1.8 2 1 1 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 CBY42021.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 CBY42021.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 CBY42021.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.10 CBY42021.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin CK_II_beta PF01214.18 CBY42022.1 - 2.9e-35 121.7 0.0 3.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CK_II_beta PF01214.18 CBY42023.1 - 1.3e-70 237.0 0.1 1.4e-70 236.8 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 CBY42023.1 - 0.084 13.0 1.3 0.14 12.2 1.3 1.5 1 1 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Med21 PF11221.8 CBY42024.1 - 4.5e-27 95.1 1.7 5.7e-27 94.7 1.7 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Pox_F16 PF04708.12 CBY42024.1 - 0.047 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein PspB PF06667.12 CBY42024.1 - 0.25 11.4 1.2 0.5 10.5 1.2 1.5 1 0 0 1 1 1 0 Phage shock protein B ZapB PF06005.12 CBY42024.1 - 2.2 8.8 6.0 15 6.1 0.2 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF3431 PF11913.8 CBY42026.1 - 0.022 14.5 0.1 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) EGF_CA PF07645.15 CBY42027.1 - 0.0023 18.1 7.2 0.0096 16.1 7.2 2.1 1 0 0 1 1 1 1 Calcium-binding EGF domain SOG2 PF10428.9 CBY42027.1 - 0.014 14.7 35.6 0.024 13.8 35.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 CBY42027.1 - 1.4 7.4 11.1 1.8 7.0 11.1 1.1 1 0 0 1 1 1 0 Utp14 protein KAR9 PF08580.10 CBY42027.1 - 2.8 6.4 23.3 3.4 6.1 23.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Phospholip_A2_1 PF00068.19 CBY42028.1 - 1e-10 42.1 11.8 1e-10 42.1 11.8 2.3 2 0 0 2 2 2 1 Phospholipase A2 Phospholip_A2_1 PF00068.19 CBY42029.1 - 1.3e-15 57.8 6.1 1.3e-15 57.8 6.1 1.6 2 0 0 2 2 2 1 Phospholipase A2 Na_Ca_ex PF01699.24 CBY42030.1 - 2.2e-16 60.2 3.0 2.2e-16 60.1 3.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF347 PF03988.12 CBY42030.1 - 0.0058 16.8 1.7 0.0085 16.3 1.7 1.5 1 1 0 1 1 1 1 Repeat of Unknown Function (DUF347) DUF2527 PF10736.9 CBY42030.1 - 0.045 13.6 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) 7tm_1 PF00001.21 CBY42033.1 - 4.3e-13 49.2 14.6 8.2e-13 48.3 8.2 2.6 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Mem_trans PF03547.18 CBY42033.1 - 0.14 10.5 4.3 0.14 10.5 2.5 1.8 1 1 1 2 2 2 0 Membrane transport protein Galactosyl_T PF01762.21 CBY42035.1 - 2.5e-12 47.0 0.2 1.2e-11 44.8 0.2 1.8 1 1 0 1 1 1 1 Galactosyltransferase fn3 PF00041.21 CBY42036.1 - 1.1e-42 144.3 5.1 5.1e-13 49.2 0.6 4.9 5 0 0 5 5 5 4 Fibronectin type III domain I-set PF07679.16 CBY42036.1 - 2.1e-14 53.4 1.0 2.4e-13 49.9 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY42036.1 - 5.7e-07 30.0 0.1 6.8e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY42036.1 - 2.8e-06 27.8 2.6 1.6 9.3 0.4 4.8 4 2 0 4 4 4 2 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 CBY42036.1 - 3.6e-05 24.0 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 Immunoglobulin domain C2-set_2 PF08205.12 CBY42036.1 - 0.011 15.8 0.0 0.036 14.1 0.0 1.8 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain fn3_2 PF16893.5 CBY42036.1 - 0.019 15.1 0.1 7.7 6.8 0.0 3.8 4 0 0 4 4 4 0 Fibronectin type III domain Receptor_2B4 PF11465.8 CBY42036.1 - 0.063 13.5 0.0 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 SRX PF09201.10 CBY42036.1 - 0.12 12.2 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit PKD_channel PF08016.12 CBY42037.1 - 3.3e-18 65.6 19.3 3.3e-18 65.6 19.3 2.7 3 0 0 3 3 3 2 Polycystin cation channel Sulfotransfer_2 PF03567.14 CBY42038.1 - 5.1e-05 23.3 0.8 0.00074 19.5 0.0 2.6 2 1 0 2 2 2 1 Sulfotransferase family Lectin_N PF03954.14 CBY42038.1 - 0.064 13.0 0.6 0.12 12.1 0.6 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF16 PF01519.16 CBY42038.1 - 0.15 12.5 2.5 0.35 11.4 0.4 2.4 2 2 1 3 3 3 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 CBY42038.1 - 8.8 6.4 10.7 0.22 11.5 1.2 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Gal-3-0_sulfotr PF06990.11 CBY42039.1 - 1.4e-24 86.8 1.0 1.7e-24 86.5 1.0 1.0 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Choline_kinase PF01633.20 CBY42040.1 - 7e-57 192.4 0.1 1.2e-56 191.6 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY42040.1 - 3.8e-11 43.4 0.0 1e-10 42.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY42040.1 - 7.7e-05 22.1 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 CBY42040.1 - 0.17 11.2 0.7 0.86 8.9 0.0 2.3 3 0 0 3 3 3 0 Protein kinase domain RELT PF12606.8 CBY42041.1 - 1.1 8.3 3.6 10 5.2 0.2 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Na_H_Exchanger PF00999.21 CBY42043.1 - 7.5e-49 166.5 29.7 8.6e-49 166.3 29.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MRP-S28 PF10213.9 CBY42043.1 - 0.09 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Trypsin PF00089.26 CBY42044.1 - 3.2e-51 174.2 0.2 4.1e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY42044.1 - 0.00074 20.4 0.0 0.0012 19.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Pkinase PF00069.25 CBY42045.1 - 7.3e-45 153.4 0.2 7.3e-45 153.4 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42045.1 - 3.2e-29 102.0 0.1 5.8e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY42045.1 - 3.8e-05 22.6 0.5 0.00087 18.2 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CBY42045.1 - 0.00044 19.8 4.6 0.00053 19.6 0.1 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Zona_pellucida PF00100.23 CBY42049.1 - 1.6e-31 110.1 4.5 2e-31 109.7 4.5 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DUF3524 PF12038.8 CBY42050.1 - 4.4e-17 62.4 0.0 1.2e-16 61.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3524) Glycos_transf_1 PF00534.20 CBY42050.1 - 9.8e-10 38.2 0.0 2.2e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBY42050.1 - 1.8e-06 28.4 0.0 1e-05 26.0 0.0 2.1 2 1 1 3 3 3 1 Glycosyl transferases group 1 Gla PF00594.20 CBY42050.1 - 0.057 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain G3P_antiterm PF04309.12 CBY42050.1 - 0.13 11.6 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator CUB PF00431.20 CBY42051.1 - 7.6e-13 48.8 0.5 4.6e-11 43.0 0.5 2.6 1 1 0 1 1 1 1 CUB domain Trypsin PF00089.26 CBY42052.1 - 2.4e-12 47.1 0.0 4.5e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY42052.1 - 0.016 16.1 0.0 0.026 15.4 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain 7tm_1 PF00001.21 CBY42058.1 - 0.0059 16.0 1.6 0.0082 15.5 1.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PIG-Y PF15159.6 CBY42058.1 - 0.03 15.2 1.9 0.051 14.5 1.4 1.7 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF2207 PF09972.9 CBY42058.1 - 0.12 11.1 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Jiraiya PF15038.6 CBY42058.1 - 0.54 9.7 5.1 2.9 7.3 0.8 2.2 2 0 0 2 2 2 0 Jiraiya Lipocalin_7 PF14651.6 CBY42060.1 - 1.3e-13 51.0 0.4 1.4e-13 50.8 0.4 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family DUF1521 PF07481.11 CBY42060.1 - 0.029 14.4 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) DnaJ PF00226.31 CBY42061.1 - 3.7e-08 33.4 0.1 0.014 15.5 0.0 2.9 2 1 1 3 3 3 2 DnaJ domain F-box PF00646.33 CBY42061.1 - 8.8e-05 22.3 0.2 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBY42061.1 - 0.00019 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF1704 PF08014.11 CBY42061.1 - 0.017 14.2 0.2 0.018 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) UxaE PF16257.5 CBY42061.1 - 0.032 12.9 0.4 0.039 12.6 0.4 1.1 1 0 0 1 1 1 0 tagaturonate epimerase PMP22_Claudin PF00822.20 CBY42064.1 - 6.7e-16 58.6 7.9 8.6e-14 51.7 0.6 2.0 1 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBY42064.1 - 0.035 13.8 13.1 2.6 7.7 13.1 2.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ig_3 PF13927.6 CBY42065.1 - 5.2e-05 23.8 0.0 0.0082 16.7 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Ig_2 PF13895.6 CBY42065.1 - 5.4e-05 23.4 0.2 0.47 10.8 0.0 3.4 2 1 1 3 3 3 2 Immunoglobulin domain I-set PF07679.16 CBY42065.1 - 5.5e-05 23.2 0.0 0.098 12.7 0.0 3.2 3 0 0 3 3 3 2 Immunoglobulin I-set domain C2-set_2 PF08205.12 CBY42065.1 - 0.00015 21.7 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 CD80-like C2-set immunoglobulin domain ig PF00047.25 CBY42065.1 - 0.0045 17.1 0.2 14 5.9 0.0 3.6 3 1 0 3 3 3 1 Immunoglobulin domain SieB PF14163.6 CBY42066.1 - 0.13 11.8 2.0 0.18 11.3 2.0 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B GPI2 PF06432.11 CBY42066.1 - 1.2 8.5 3.9 1.6 8.1 3.9 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Hid1 PF12722.7 CBY42067.1 - 0.15 10.2 7.2 0.16 10.1 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CBY42067.1 - 0.38 9.5 10.3 0.44 9.4 10.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 CBY42067.1 - 1.4 8.4 7.9 1.9 8.0 7.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Na_Pi_cotrans PF02690.15 CBY42068.1 - 2.6e-19 69.7 6.0 3.8e-19 69.2 6.0 1.2 1 0 0 1 1 1 1 Na+/Pi-cotransporter MgtE PF01769.16 CBY42068.1 - 0.084 13.3 6.4 0.17 12.3 1.1 2.3 1 1 0 2 2 2 0 Divalent cation transporter DUF4212 PF13937.6 CBY42068.1 - 0.098 13.1 0.7 0.098 13.1 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Paf67 PF10255.9 CBY42069.1 - 2e-91 307.0 1.7 2.4e-91 306.7 1.7 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ANAPC5 PF12862.7 CBY42069.1 - 0.0044 17.1 0.3 0.12 12.4 0.0 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 CBY42069.1 - 0.0065 16.5 1.0 0.23 11.6 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY42069.1 - 0.0075 16.5 0.8 0.016 15.5 0.4 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBY42069.1 - 0.012 16.2 1.0 1.4 9.7 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY42069.1 - 0.093 13.0 1.1 0.65 10.3 1.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBY42069.1 - 0.12 12.3 1.9 2.2 8.2 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBY42069.1 - 0.13 12.4 0.2 9 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ammonium_transp PF00909.21 CBY42070.1 - 1.4e-78 264.4 13.1 4.4e-77 259.4 13.1 2.5 1 1 0 1 1 1 1 Ammonium Transporter Family DUF1129 PF06570.11 CBY42070.1 - 0.0096 15.4 3.4 0.0096 15.4 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) ThrE PF06738.12 CBY42070.1 - 0.2 11.0 6.1 0.094 12.1 0.7 2.5 2 0 0 2 2 2 0 Putative threonine/serine exporter CASP_C PF08172.12 CBY42071.1 - 0.1 11.9 9.1 0.35 10.2 9.1 2.1 1 1 0 1 1 1 0 CASP C terminal Dynein_attach_N PF15867.5 CBY42071.1 - 0.14 12.2 5.0 0.38 10.7 0.1 3.1 2 1 1 3 3 3 0 Dynein attachment factor N-terminus YscO PF07321.12 CBY42071.1 - 0.5 10.3 12.0 0.036 14.0 6.5 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO SWI-SNF_Ssr4 PF08549.10 CBY42071.1 - 9.6 4.7 10.0 11 4.4 10.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Darcynin PF17074.5 CBY42072.1 - 0.11 12.7 0.2 0.13 12.5 0.2 1.0 1 0 0 1 1 1 0 Darcynin, domain of unknown function Adeno_E3_CR2 PF02439.15 CBY42075.1 - 0.005 16.6 1.0 0.0082 15.9 1.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 BatA PF07584.11 CBY42075.1 - 0.019 15.3 1.2 0.1 13.0 0.7 2.0 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal TMEM154 PF15102.6 CBY42075.1 - 0.024 14.5 0.5 0.024 14.5 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 CBY42075.1 - 0.024 14.2 0.2 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Herpes_gE PF02480.16 CBY42075.1 - 0.033 12.9 0.0 0.033 12.9 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Chordopox_L2 PF05803.12 CBY42075.1 - 0.035 13.9 3.9 0.047 13.5 3.9 1.1 1 0 0 1 1 1 0 Chordopoxvirus L2 protein ODV-E18 PF10717.9 CBY42075.1 - 0.045 13.6 0.8 0.059 13.3 0.8 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 CBY42075.1 - 0.048 14.5 2.2 0.08 13.8 2.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CBY42075.1 - 0.066 13.5 0.2 0.076 13.3 0.2 1.2 1 0 0 1 1 1 0 Orf78 (ac78) RIFIN PF02009.16 CBY42075.1 - 0.15 12.0 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 Rifin RCR PF12273.8 CBY42075.1 - 0.7 10.6 3.0 1.2 9.9 3.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Ac76 PF05814.11 CBY42075.1 - 0.88 9.6 7.0 1.3 9.1 7.0 1.5 1 1 0 1 1 1 0 Orf76 (Ac76) Comm PF15957.5 CBY42075.1 - 1 9.8 3.8 1.2 9.5 3.5 1.3 1 1 0 1 1 1 0 Commissureless IQ PF00612.27 CBY42077.1 - 0.00019 20.9 9.4 0.029 14.2 1.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif ARL6IP6 PF15062.6 CBY42077.1 - 0.56 10.4 2.2 0.79 9.9 0.3 2.2 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Myosin_head PF00063.21 CBY42078.1 - 9.7e-61 205.8 3.3 1.3e-60 205.5 3.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 CBY42078.1 - 2.5e-10 39.2 16.0 3.8e-05 23.1 0.2 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif IQCJ-SCHIP1 PF15157.6 CBY42078.1 - 9.8 6.0 8.0 1.1 9.1 1.2 2.7 2 1 1 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif AA_permease_2 PF13520.6 CBY42079.1 - 9e-52 176.3 29.9 1.3e-51 175.8 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBY42079.1 - 1.9e-16 59.7 29.0 2.5e-16 59.4 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease PfkB PF00294.24 CBY42080.1 - 8.7e-28 97.5 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RNA_pol_Rpb1_R PF05001.13 CBY42081.1 - 0.0008 19.6 35.0 0.0016 18.7 13.2 8.8 4 2 4 8 8 8 5 RNA polymerase Rpb1 C-terminal repeat Amidase PF01425.21 CBY42082.1 - 3.3e-34 118.6 1.0 2.9e-19 69.4 0.0 2.8 2 1 0 2 2 2 2 Amidase Lectin_C PF00059.21 CBY42083.1 - 6.8e-12 46.1 0.2 1.7e-11 44.8 0.2 1.7 1 0 0 1 1 1 1 Lectin C-type domain Methyltransf_25 PF13649.6 CBY42084.1 - 3.5e-09 37.3 0.2 2.4e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBY42084.1 - 2.5e-08 33.7 0.1 6.4e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBY42084.1 - 5.7e-08 32.5 0.1 1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CBY42084.1 - 1.7e-06 28.5 0.4 2e-05 25.1 0.1 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBY42084.1 - 1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 CBY42084.1 - 2e-05 24.4 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY42084.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY42084.1 - 0.0017 19.1 0.2 0.005 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CBY42084.1 - 0.0019 17.5 0.1 0.004 16.5 0.1 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CBY42084.1 - 0.0045 16.9 0.1 0.0082 16.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CBY42084.1 - 0.024 13.9 0.7 0.043 13.1 0.2 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Cons_hypoth95 PF03602.15 CBY42084.1 - 0.026 14.2 0.1 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 CBY42084.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CBY42084.1 - 0.063 13.4 0.1 0.23 11.5 0.1 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase AlaDh_PNT_C PF01262.21 CBY42084.1 - 0.091 12.0 0.7 0.16 11.2 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-RING_5 PF14634.6 CBY42086.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain TSP_1 PF00090.19 CBY42090.1 - 2.9e-11 43.4 39.3 8.2e-08 32.4 10.9 4.4 4 0 0 4 4 4 3 Thrombospondin type 1 domain cEGF PF12662.7 CBY42090.1 - 3.5e-05 23.6 4.6 0.00021 21.1 4.6 2.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like CAP PF00188.26 CBY42090.1 - 0.00014 22.7 0.3 0.0024 18.7 0.3 2.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CUB PF00431.20 CBY42090.1 - 0.12 12.7 2.0 0.16 12.3 0.1 2.3 2 0 0 2 2 2 0 CUB domain hEGF PF12661.7 CBY42090.1 - 0.6 10.8 11.0 0.71 10.6 7.2 3.5 2 0 0 2 2 2 0 Human growth factor-like EGF AdoHcyase_NAD PF00670.21 CBY42093.1 - 7.5e-78 260.2 3.1 1e-77 259.7 3.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.17 CBY42093.1 - 2.6e-66 223.8 0.0 2.3e-52 178.0 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.19 CBY42093.1 - 1.2e-09 37.8 0.2 1.8e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBY42093.1 - 7.4e-07 28.9 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 CBY42093.1 - 6.4e-05 22.3 2.7 0.00026 20.4 2.7 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.21 CBY42093.1 - 0.00039 19.8 2.7 0.0011 18.3 2.7 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CBY42093.1 - 0.0026 18.2 0.3 0.0055 17.1 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 CBY42093.1 - 0.017 15.3 0.8 0.07 13.4 0.8 2.0 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 CBY42093.1 - 0.018 15.1 0.1 0.043 13.9 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CBY42093.1 - 0.035 13.8 1.4 0.39 10.4 1.4 2.1 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TatD_DNase PF01026.21 CBY42094.1 - 1.4e-47 162.3 0.0 2.8e-47 161.2 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase SRCR_2 PF15494.6 CBY42094.1 - 1.4 9.5 4.3 4.9 7.8 4.3 1.9 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF966 PF06136.13 CBY42094.1 - 2.8 7.6 17.9 3.9 7.1 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nucleoporin_FG PF13634.6 CBY42095.1 - 1.3e-06 29.2 21.3 1.3e-06 29.2 21.3 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF2048 PF09752.9 CBY42095.1 - 0.0076 15.4 2.9 0.013 14.6 2.9 1.4 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Nucleoporin_FG2 PF15967.5 CBY42095.1 - 0.49 8.9 72.7 0.18 10.3 39.6 2.0 1 1 1 2 2 2 0 Nucleoporin FG repeated region B277 PF17623.2 CBY42095.1 - 7.9 5.5 4.7 12 4.9 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function TMEM154 PF15102.6 CBY42096.1 - 1.7 8.5 13.1 3.3 7.6 5.8 2.5 2 0 0 2 2 2 0 TMEM154 protein family AJAP1_PANP_C PF15298.6 CBY42096.1 - 6 7.0 21.7 4.4 7.5 10.9 2.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus SSP160 PF06933.11 CBY42096.1 - 7.7 4.6 36.4 0.23 9.6 17.7 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 HORMA PF02301.18 CBY42098.1 - 3.6e-11 43.1 1.4 4.5e-11 42.8 1.4 1.1 1 0 0 1 1 1 1 HORMA domain BsuBI_PstI_RE PF06616.11 CBY42098.1 - 0.055 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain bacHORMA_1 PF18138.1 CBY42098.1 - 0.077 12.9 0.2 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial HORMA domain family 1 KH_10 PF17905.1 CBY42098.1 - 0.086 13.3 0.5 0.23 11.9 0.2 1.9 2 0 0 2 2 2 0 GLD-3 KH domain 5 DUF3435 PF11917.8 CBY42099.1 - 0.049 12.5 0.6 0.056 12.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FerB PF08150.12 CBY42100.1 - 1.7e-29 102.2 0.0 3.8e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 FerB (NUC096) domain C2 PF00168.30 CBY42100.1 - 8.2e-12 45.3 0.0 7.5e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain PAS_11 PF14598.6 CBY42102.1 - 4.1e-10 39.8 0.3 8.8e-10 38.7 0.3 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 CBY42102.1 - 2.5e-09 37.3 0.1 4.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CBY42102.1 - 0.18 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 PAS fold YL1_C PF08265.11 CBY42103.1 - 0.98 9.2 0.1 0.98 9.2 0.1 2.4 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain Pterin_bind PF00809.22 CBY42104.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Pterin binding enzyme MIP PF00230.20 CBY42107.1 - 0.00066 19.4 0.3 0.00072 19.3 0.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 CBY42108.1 - 4.7e-19 68.5 32.2 5.4e-19 68.3 32.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Dynein_C PF18199.1 CBY42109.1 - 4.1e-44 151.0 0.7 4.1e-44 151.0 0.7 2.0 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY42109.1 - 5.2e-34 117.4 0.0 1.3e-33 116.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBY42109.1 - 9.5e-33 112.8 0.1 4.2e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_9 PF12781.7 CBY42109.1 - 1.7e-10 40.4 3.6 2.4e-08 33.4 3.2 2.8 2 0 0 2 2 2 2 ATP-binding dynein motor region NUC194 PF08163.12 CBY42109.1 - 0.061 12.2 1.3 0.22 10.4 0.1 2.2 2 0 0 2 2 2 0 NUC194 domain Fzo_mitofusin PF04799.13 CBY42109.1 - 0.36 10.4 2.0 1.3 8.6 2.0 2.0 1 0 0 1 1 1 0 fzo-like conserved region Fib_alpha PF08702.10 CBY42109.1 - 0.96 9.6 8.3 12 6.0 0.3 3.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family COX6C PF02937.15 CBY42111.1 - 0.12 12.5 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc SPC25 PF06703.11 CBY42112.1 - 1.4e-34 119.3 0.9 1.6e-34 119.0 0.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) BTB PF00651.31 CBY42113.1 - 2.5e-24 85.6 0.1 4.7e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain HMG_box PF00505.19 CBY42113.1 - 1.1e-07 32.1 0.1 2.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CBY42113.1 - 0.00088 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain HD-ZIP_N PF04618.12 CBY42113.1 - 0.092 13.3 0.4 0.092 13.3 0.4 2.1 2 0 0 2 2 2 0 HD-ZIP protein N terminus Phospholip_A2_1 PF00068.19 CBY42114.1 - 8.8e-20 71.2 7.2 8.8e-20 71.2 7.2 2.2 2 0 0 2 2 2 1 Phospholipase A2 Histone_H2A_C PF16211.5 CBY42116.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY42116.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY42116.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBY42117.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY42117.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY42117.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY42117.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY42117.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein rve PF00665.26 CBY42119.1 - 5.8e-13 49.1 0.0 9.5e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY42119.1 - 6.5e-08 32.6 0.1 1.6e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag_pre-integrs PF13976.6 CBY42119.1 - 0.00049 19.9 0.2 0.0022 17.8 0.1 2.2 1 1 0 1 1 1 1 GAG-pre-integrase domain DNA_PPF PF02916.15 CBY42119.1 - 0.014 15.8 0.1 0.027 14.9 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor zf-H3C2 PF16721.5 CBY42119.1 - 0.016 15.6 0.1 0.041 14.3 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding zf-H2C2 PF09337.10 CBY42119.1 - 0.021 15.0 0.1 0.05 13.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger fn3 PF00041.21 CBY42120.1 - 3e-15 56.3 2.9 0.032 14.6 0.0 7.9 7 0 0 7 7 7 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBY42120.1 - 5.5e-05 23.6 7.6 6.6 7.4 0.1 6.3 5 2 1 6 6 6 3 Purple acid Phosphatase, N-terminal domain DUF1410 PF07198.11 CBY42120.1 - 1.9 9.0 5.0 11 6.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1410) FXa_inhibition PF14670.6 CBY42122.1 - 0.78 10.1 7.8 0.27 11.5 4.3 2.1 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site WD40 PF00400.32 CBY42123.1 - 0.18 12.7 0.3 0.18 12.7 0.3 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Stathmin PF00836.19 CBY42125.1 - 3.8e-10 39.8 4.1 4.1e-10 39.7 4.1 1.0 1 0 0 1 1 1 1 Stathmin family DAGK_cat PF00781.24 CBY42126.1 - 4.6e-10 39.2 0.2 7.4e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RhoGAP PF00620.27 CBY42130.1 - 0.00025 20.9 0.1 0.00036 20.4 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain TFIIE_alpha PF02002.17 CBY42130.1 - 0.0054 16.6 0.3 0.11 12.4 0.1 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit TPR_MLP1_2 PF07926.12 CBY42132.1 - 0.0034 17.4 5.2 0.0043 17.1 4.6 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 CBY42132.1 - 0.0049 16.9 4.7 0.0062 16.6 4.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Tmemb_cc2 PF10267.9 CBY42132.1 - 0.005 16.0 6.2 0.0062 15.7 6.2 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein ZapB PF06005.12 CBY42132.1 - 0.0092 16.4 5.2 0.018 15.5 3.4 2.1 2 0 0 2 2 2 1 Cell division protein ZapB DUF4094 PF13334.6 CBY42132.1 - 0.034 14.6 2.6 0.052 14.0 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 CBY42132.1 - 0.07 13.5 8.2 0.37 11.2 3.9 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 CBY42132.1 - 0.1 12.4 4.0 0.065 13.0 1.9 1.6 2 0 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 CBY42132.1 - 0.73 10.0 7.2 0.58 10.3 2.1 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain DnaJ PF00226.31 CBY42133.1 - 2.5e-09 37.1 0.1 4.1e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Rpn3_C PF08375.11 CBY42134.1 - 1e-19 70.7 3.4 1e-19 70.7 3.4 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CBY42134.1 - 1.1e-19 70.9 0.1 9e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain DrsE_2 PF13686.6 CBY42136.1 - 0.013 15.4 1.0 0.022 14.7 1.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family DUF4129 PF13559.6 CBY42137.1 - 0.012 15.8 2.7 0.034 14.4 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Zona_pellucida PF00100.23 CBY42139.1 - 2e-18 67.1 0.0 2.3e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain eIF3g PF12353.8 CBY42140.1 - 7.9e-18 65.1 4.8 1e-17 64.7 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF1947 PF09183.10 CBY42141.1 - 0.026 14.8 1.6 0.99 9.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Arm PF00514.23 CBY42143.1 - 2.4e-16 59.2 0.0 0.00012 22.0 0.0 5.3 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBY42143.1 - 5.5e-06 26.3 0.3 0.0092 16.0 0.2 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RICTOR_N PF14664.6 CBY42143.1 - 0.0001 21.4 2.8 0.12 11.3 1.4 2.7 1 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term UME PF08064.13 CBY42143.1 - 0.025 14.5 0.4 0.51 10.3 0.0 2.9 3 0 0 3 3 3 0 UME (NUC010) domain HEAT PF02985.22 CBY42143.1 - 0.099 12.9 0.0 46 4.6 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat CLASP_N PF12348.8 CBY42143.1 - 0.11 12.0 0.7 7.3 6.1 0.0 2.9 3 1 0 3 3 3 0 CLASP N terminal TMF_DNA_bd PF12329.8 CBY42145.1 - 0.12 12.3 1.0 0.21 11.6 0.3 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TACC_C PF05010.14 CBY42148.1 - 3.2e-08 33.6 14.1 3.4e-08 33.5 14.1 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Glutaredoxin2_C PF04399.13 CBY42148.1 - 0.019 14.8 1.2 0.028 14.2 0.8 1.5 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain ATP_bind_1 PF03029.17 CBY42148.1 - 0.059 13.1 1.1 0.071 12.9 1.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Fungal_TACC PF12709.7 CBY42148.1 - 0.19 12.2 9.4 0.26 11.8 3.3 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cdh1_DBD_1 PF18196.1 CBY42149.1 - 0.015 15.6 10.9 0.88 9.9 0.4 2.1 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Lipoprotein_10 PF03202.13 CBY42149.1 - 9.6 6.7 11.0 0.98 9.9 4.9 2.1 1 1 1 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Cpn60_TCP1 PF00118.24 CBY42150.1 - 1.1e-105 354.1 2.7 1.2e-105 354.0 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prp31_C PF09785.9 CBY42151.1 - 1.1e-42 145.8 2.2 1.5e-42 145.3 2.2 1.2 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 CBY42151.1 - 0.00093 18.7 0.5 0.0012 18.3 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Host_attach PF10116.9 CBY42153.1 - 0.031 14.9 0.4 0.031 14.9 0.4 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells eIF-5_eIF-2B PF01873.17 CBY42154.1 - 3.7e-36 123.5 0.0 4.2e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Myosin_tail_1 PF01576.19 CBY42155.1 - 1e-07 30.2 8.6 1.1e-07 30.1 8.6 1.0 1 0 0 1 1 1 1 Myosin tail KxDL PF10241.9 CBY42155.1 - 7.7e-05 22.9 4.7 7.7e-05 22.9 4.7 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein DUF677 PF05055.12 CBY42155.1 - 0.001 18.1 3.3 0.0012 17.8 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Occludin_ELL PF07303.13 CBY42155.1 - 0.0028 18.3 3.4 0.0034 18.1 3.4 1.1 1 0 0 1 1 1 1 Occludin homology domain GAS PF13851.6 CBY42155.1 - 0.0033 16.8 9.7 0.0046 16.3 9.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 CBY42155.1 - 0.017 14.9 5.9 0.019 14.8 5.9 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 CBY42155.1 - 0.018 15.1 14.1 0.021 14.9 14.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.12 CBY42155.1 - 0.035 13.7 8.8 0.044 13.3 8.8 1.1 1 0 0 1 1 1 0 PspA/IM30 family CENP-H PF05837.12 CBY42155.1 - 0.037 14.4 10.4 0.049 14.0 10.4 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IFT57 PF10498.9 CBY42155.1 - 0.05 12.6 8.6 0.056 12.4 8.6 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 CBY42155.1 - 0.064 12.7 12.1 0.074 12.5 12.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Med4 PF10018.9 CBY42155.1 - 0.073 12.7 6.4 0.13 11.9 6.4 1.4 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 MIP-T3_C PF17749.1 CBY42155.1 - 0.084 12.8 7.7 0.031 14.2 5.1 1.5 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Syntaxin-6_N PF09177.11 CBY42155.1 - 0.12 13.0 5.8 0.14 12.8 5.8 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 CBY42155.1 - 0.13 12.5 11.2 0.46 10.7 6.3 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 BLOC1_2 PF10046.9 CBY42155.1 - 0.23 11.8 6.7 0.071 13.4 1.9 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1043 PF06295.12 CBY42155.1 - 0.23 11.4 5.4 0.7 9.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF1664 PF07889.12 CBY42155.1 - 0.28 11.2 5.6 0.41 10.7 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HSCB_C PF07743.13 CBY42155.1 - 0.3 11.6 11.3 0.54 10.8 9.4 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3972 PF13118.6 CBY42155.1 - 0.31 11.5 7.1 0.25 11.8 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF724 PF05266.14 CBY42155.1 - 0.35 10.7 10.3 0.38 10.6 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3584 PF12128.8 CBY42155.1 - 0.38 8.2 9.6 0.42 8.1 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 CBY42155.1 - 0.39 10.9 7.8 0.45 10.7 7.8 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 CBY42155.1 - 0.41 10.7 7.3 0.64 10.1 3.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3450 PF11932.8 CBY42155.1 - 0.48 9.7 8.6 0.12 11.6 4.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 CBY42155.1 - 0.49 9.9 10.6 0.55 9.8 10.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3958 PF13125.6 CBY42155.1 - 0.57 10.4 9.4 1.9 8.7 9.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3958) Spc7 PF08317.11 CBY42155.1 - 0.61 8.9 13.2 1 8.2 13.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 CBY42155.1 - 0.71 9.9 10.6 0.93 9.6 10.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF465 PF04325.13 CBY42155.1 - 0.84 9.7 5.3 2 8.6 0.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF465) TMPIT PF07851.13 CBY42155.1 - 0.84 8.8 8.7 0.95 8.6 8.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 CBY42155.1 - 0.85 9.9 10.8 1.8 8.8 10.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SIKE PF05769.11 CBY42155.1 - 0.88 9.5 14.5 1.9 8.4 0.5 3.0 2 1 1 3 3 3 0 SIKE family FapA PF03961.13 CBY42155.1 - 0.98 7.9 9.0 1.1 7.7 9.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 CBY42155.1 - 0.99 10.1 6.9 3 8.6 6.9 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) 5_nucleotid PF05761.14 CBY42155.1 - 2.2 7.1 4.8 2.3 7.0 4.8 1.0 1 0 0 1 1 1 0 5' nucleotidase family DUF4404 PF14357.6 CBY42155.1 - 2.2 8.9 8.8 2.6 8.7 6.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Spc24 PF08286.11 CBY42155.1 - 6 7.2 12.6 5.4 7.3 5.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4349 PF14257.6 CBY42155.1 - 7.8 5.9 9.4 16 4.9 8.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Myosin_tail_1 PF01576.19 CBY42156.1 - 2.3e-38 131.7 66.3 2.6e-38 131.5 66.3 1.0 1 0 0 1 1 1 1 Myosin tail DUF2935 PF11155.8 CBY42156.1 - 0.00027 21.3 5.9 0.066 13.6 5.9 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) Filament PF00038.21 CBY42156.1 - 0.0042 16.7 59.9 0.0042 16.7 54.7 2.1 1 1 1 2 2 2 1 Intermediate filament protein Tropomyosin PF00261.20 CBY42156.1 - 0.013 14.9 64.3 0.11 11.9 9.6 4.3 1 1 3 4 4 4 0 Tropomyosin CcmF_C PF16327.5 CBY42156.1 - 0.071 12.4 4.6 0.047 13.0 2.2 1.8 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal Asp4 PF16996.5 CBY42156.1 - 0.29 11.0 2.3 0.8 9.5 2.3 1.8 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 PspA_IM30 PF04012.12 CBY42156.1 - 0.84 9.2 63.1 0.33 10.5 18.2 4.0 1 1 2 3 3 3 0 PspA/IM30 family DUF812 PF05667.11 CBY42156.1 - 1.1 8.0 57.6 3.1 6.6 11.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF745 PF05335.13 CBY42156.1 - 1.2 8.8 51.4 3.3 7.4 9.4 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) APG6_N PF17675.1 CBY42156.1 - 1.2 9.6 66.7 1.9 9.0 6.4 4.3 1 1 3 4 4 4 0 Apg6 coiled-coil region DUF3584 PF12128.8 CBY42156.1 - 3.7 4.9 61.4 0.028 12.0 15.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DASH_Dad4 PF08650.10 CBY42156.1 - 7.3 6.6 19.0 0.84 9.7 0.5 4.5 2 2 2 5 5 5 0 DASH complex subunit Dad4 ADIP PF11559.8 CBY42157.1 - 0.0021 18.2 13.3 0.0021 18.2 13.3 3.2 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 CBY42157.1 - 0.0034 17.6 8.4 0.0034 17.6 8.4 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 CBY42157.1 - 0.07 13.5 17.2 0.66 10.4 0.8 4.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) ALMT PF11744.8 CBY42157.1 - 0.28 10.0 13.4 0.36 9.6 13.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter GAS PF13851.6 CBY42157.1 - 0.66 9.3 32.2 1.3 8.4 18.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 CBY42157.1 - 0.72 9.6 19.1 0.18 11.6 11.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 YabA PF06156.13 CBY42157.1 - 2 9.1 26.1 0.11 13.1 5.8 3.2 1 1 1 3 3 3 0 Initiation control protein YabA Glutaredoxin2_C PF04399.13 CBY42157.1 - 2.5 7.9 7.2 0.45 10.4 0.7 2.6 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain Jnk-SapK_ap_N PF09744.9 CBY42157.1 - 4.5 7.5 36.5 0.7 10.1 8.2 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 CBY42157.1 - 8 6.9 27.7 6.2 7.2 8.3 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2203 PF09969.9 CBY42157.1 - 8.2 7.2 18.9 0.11 13.3 5.5 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 CBY42157.1 - 9.2 6.3 17.1 6.3 6.9 4.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF5526 PF17664.1 CBY42159.1 - 0.04 13.5 5.1 0.085 12.4 5.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5526) DUF2407_C PF13373.6 CBY42160.1 - 0.0016 18.6 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain Lig_chan PF00060.26 CBY42160.1 - 0.096 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4456 PF14644.6 CBY42162.1 - 5e-38 130.9 10.8 1e-37 129.9 10.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) YtxH PF12732.7 CBY42162.1 - 0.17 12.4 1.6 25 5.5 0.3 3.7 2 2 0 2 2 2 0 YtxH-like protein Spore_III_AB PF09548.10 CBY42162.1 - 0.27 11.3 6.6 0.71 10.0 4.5 2.6 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Orbi_VP1 PF05788.12 CBY42164.1 - 0.006 14.3 0.2 0.006 14.3 0.2 1.0 1 0 0 1 1 1 1 Orbivirus RNA-dependent RNA polymerase (VP1) Pkinase PF00069.25 CBY42166.1 - 5.9e-15 55.3 0.4 6.9e-15 55.1 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42166.1 - 1.1e-08 34.7 0.4 1.4e-08 34.4 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Flp_N PF03930.14 CBY42166.1 - 0.0051 16.8 0.1 0.0062 16.5 0.1 1.1 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus Kdo PF06293.14 CBY42166.1 - 0.026 13.9 0.1 0.026 13.9 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GerE PF00196.19 CBY42166.1 - 0.059 12.9 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family RRM_1 PF00076.22 CBY42167.1 - 2.9e-23 81.5 0.0 4.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CBY42167.1 - 1.1e-20 73.9 1.2 1.6e-20 73.3 1.2 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 CBY42167.1 - 0.034 14.3 0.0 0.072 13.2 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif PHM7_cyt PF14703.6 CBY42167.1 - 0.036 14.3 0.1 1 9.5 0.0 2.4 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 CBY42167.1 - 0.048 13.5 0.0 0.092 12.5 0.0 1.4 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Iso_dh PF00180.20 CBY42168.1 - 4.8e-78 262.8 0.0 5.4e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GXWXG PF14231.6 CBY42169.1 - 0.098 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 GXWXG protein Selenoprotein_S PF06936.11 CBY42170.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) Selenoprotein_S PF06936.11 CBY42171.1 - 6.7e-12 45.6 8.5 8.4e-12 45.3 8.5 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) CHCH PF06747.13 CBY42172.1 - 0.0053 16.8 2.1 0.0077 16.3 2.1 1.3 1 0 0 1 1 1 1 CHCH domain Ribosomal_60s PF00428.19 CBY42172.1 - 1.2 9.8 17.4 0.25 12.0 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2076 PF09849.9 CBY42172.1 - 3 7.8 21.1 14 5.7 20.8 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ank_2 PF12796.7 CBY42174.1 - 1.7e-19 70.2 0.1 9.1e-11 42.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY42174.1 - 1.4e-15 57.4 0.2 3.8e-07 30.5 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SET PF00856.28 CBY42174.1 - 2e-15 57.6 0.2 3.6e-13 50.2 0.2 2.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 CBY42174.1 - 9.6e-13 48.7 5.2 9.6e-13 48.7 5.2 2.7 2 0 0 2 2 2 1 Pre-SET motif Ank_3 PF13606.6 CBY42174.1 - 2.9e-12 45.6 0.0 0.26 12.0 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBY42174.1 - 6.1e-11 42.3 0.5 0.037 14.4 0.0 4.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBY42174.1 - 5.3e-06 26.7 0.1 1.2 9.7 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Transglut_i_TM PF14400.6 CBY42174.1 - 0.0065 16.5 0.8 0.54 10.3 0.0 2.4 2 0 0 2 2 2 1 Inactive transglutaminase fused to 7 transmembrane helices zf-CCHC_3 PF13917.6 CBY42175.1 - 1.8e-06 27.8 0.0 1.8e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Zinc knuckle Rtf2 PF04641.12 CBY42175.1 - 0.001 18.5 4.3 0.001 18.5 4.3 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-CCHC PF00098.23 CBY42175.1 - 0.0015 18.5 4.0 0.0024 17.9 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Transformer PF06495.11 CBY42175.1 - 0.048 13.8 14.9 0.05 13.7 14.9 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF2229 PF09989.9 CBY42175.1 - 0.72 9.5 3.9 0.79 9.3 3.8 1.2 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2207 PF09972.9 CBY42175.1 - 2.3 6.9 4.8 2.8 6.6 4.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S49_N PF08496.10 CBY42175.1 - 3.5 7.7 10.7 5 7.2 10.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 CBY42175.1 - 5.8 5.7 14.3 7.1 5.4 14.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4228 PF14009.6 CBY42175.1 - 8.2 6.8 11.2 12 6.2 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Pkinase PF00069.25 CBY42177.1 - 1.9e-69 234.0 0.3 2.9e-69 233.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42177.1 - 9.9e-39 133.2 0.2 1.8e-38 132.3 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CBY42177.1 - 3.5e-29 100.8 0.4 1.6e-16 60.3 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 CBY42177.1 - 1.2e-05 24.3 0.0 2.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Knl1_RWD_C PF18210.1 CBY42177.1 - 0.15 12.6 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Knl1 RWD C-terminal domain Histone PF00125.24 CBY42178.1 - 3.1e-51 173.1 2.2 3.5e-51 173.0 2.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CBY42178.1 - 0.00017 21.7 0.5 0.00026 21.1 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CBY42178.1 - 0.00028 21.5 1.6 0.00031 21.3 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 CBY42178.1 - 0.0008 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CBY42178.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TMA7 PF09072.10 CBY42178.1 - 0.11 13.4 3.0 0.21 12.4 3.0 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Sirohm_synth_M PF14824.6 CBY42178.1 - 1.3 8.6 3.8 4.7 6.8 0.4 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DUF1664 PF07889.12 CBY42179.1 - 0.53 10.3 11.5 0.37 10.8 9.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) E2F_CC-MB PF16421.5 CBY42179.1 - 1 9.7 8.3 0.57 10.6 0.3 2.8 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF3552 PF12072.8 CBY42179.1 - 2.7 7.4 35.4 0.26 10.7 12.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) SurA_N_3 PF13624.6 CBY42179.1 - 3.3 7.5 12.9 0.26 11.1 8.0 1.7 2 0 0 2 2 2 0 SurA N-terminal domain RRM_1 PF00076.22 CBY42180.1 - 5.1e-12 45.4 0.0 7.5e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sod_Cu PF00080.20 CBY42180.1 - 0.029 14.5 0.2 0.04 14.1 0.2 1.5 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) DNA_ligase_aden PF01653.18 CBY42181.1 - 0.049 12.7 0.1 0.052 12.6 0.1 1.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain APG17 PF04108.12 CBY42181.1 - 0.062 12.4 0.4 0.062 12.4 0.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 TbpB_C PF17483.2 CBY42181.1 - 0.082 13.3 0.2 0.24 11.8 0.2 1.9 1 1 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B CART PF06373.11 CBY42181.1 - 0.083 13.1 0.1 1.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) SH3_1 PF00018.28 CBY42182.1 - 1.6e-05 24.4 0.2 4.2e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBY42182.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_9 PF14604.6 CBY42182.1 - 0.029 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Kunitz_BPTI PF00014.23 CBY42182.1 - 0.15 12.3 1.2 0.86 9.9 0.1 2.1 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF1639 PF07797.14 CBY42183.1 - 0.086 12.8 0.2 0.086 12.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) NPC1_N PF16414.5 CBY42184.1 - 1.3e-47 162.5 18.3 1.6e-46 158.8 6.3 3.1 2 2 0 2 2 2 2 Niemann-Pick C1 N terminus Fer4_7 PF12838.7 CBY42184.1 - 5.4 7.7 16.1 12 6.6 2.7 3.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain EFG_IV PF03764.18 CBY42185.1 - 0.00025 20.8 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 CBY42186.1 - 9.2e-57 191.7 0.0 1.3e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY42186.1 - 7.7e-07 29.4 0.4 2.1e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CBY42186.1 - 5.6e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CBY42186.1 - 0.00024 21.2 0.0 0.0007 19.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBY42186.1 - 0.077 12.4 0.1 0.33 10.4 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CBY42186.1 - 0.079 12.9 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase GvpO PF05800.11 CBY42186.1 - 0.22 11.5 0.8 9.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Gas vesicle synthesis protein GvpO zf-C2H2 PF00096.26 CBY42188.1 - 0.2 12.2 8.4 0.25 11.9 0.0 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY42188.1 - 0.59 11.1 7.2 0.6 11.1 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger COPI_C PF06957.11 CBY42189.1 - 1.1e-36 126.5 0.1 1.2e-36 126.4 0.1 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nab2 PF11517.8 CBY42190.1 - 0.041 14.2 0.0 0.041 14.2 0.0 1.2 1 1 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) ABC_tran PF00005.27 CBY42191.1 - 3.4e-31 108.6 0.0 2.5e-15 57.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CBY42191.1 - 1.3e-13 50.5 6.9 2.9e-13 49.4 6.9 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CBY42191.1 - 4.6e-10 39.3 2.5 0.0028 17.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBY42191.1 - 2.8e-09 37.2 3.7 0.19 11.5 1.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CBY42191.1 - 1.1e-07 31.4 3.6 1.1e-07 31.4 3.6 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CBY42191.1 - 2e-06 27.8 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBY42191.1 - 5.3e-06 26.9 0.0 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBY42191.1 - 9.6e-06 25.5 0.2 0.041 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBY42191.1 - 4.3e-05 23.8 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CBY42191.1 - 9.6e-05 22.4 0.0 0.095 12.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CBY42191.1 - 9.6e-05 22.4 0.0 0.0024 17.9 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_6 PF12837.7 CBY42191.1 - 0.00031 20.7 12.5 0.00046 20.1 2.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 CBY42191.1 - 0.00035 20.3 0.1 0.54 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CBY42191.1 - 0.00039 21.0 0.1 0.072 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CBY42191.1 - 0.00041 20.3 0.3 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 CBY42191.1 - 0.00046 20.6 0.0 0.27 11.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBY42191.1 - 0.00079 19.2 0.1 0.27 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CBY42191.1 - 0.0015 19.0 1.0 0.0015 19.0 1.0 2.4 1 1 0 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 CBY42191.1 - 0.0018 18.4 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBY42191.1 - 0.0018 18.8 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBY42191.1 - 0.0019 18.6 0.2 3.7 8.0 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 CBY42191.1 - 0.0033 17.7 0.1 0.72 10.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 CBY42191.1 - 0.0039 17.2 1.0 0.0039 17.2 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 CBY42191.1 - 0.004 17.2 12.6 0.0095 16.0 12.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBY42191.1 - 0.0052 16.9 1.4 0.0052 16.9 1.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_30 PF13604.6 CBY42191.1 - 0.0053 16.5 0.9 0.71 9.6 0.1 2.9 4 0 0 4 4 2 1 AAA domain SRP54 PF00448.22 CBY42191.1 - 0.009 15.7 2.8 0.27 10.8 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_9 PF13187.6 CBY42191.1 - 0.0093 16.1 13.4 0.018 15.2 13.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 CBY42191.1 - 0.015 14.8 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 CBY42191.1 - 0.017 14.3 0.1 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Thymidylate_kin PF02223.17 CBY42191.1 - 0.02 14.6 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_16 PF13484.6 CBY42191.1 - 0.045 14.7 1.8 0.045 14.7 1.8 2.6 1 1 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 CBY42191.1 - 0.053 13.5 0.1 3.6 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 CBY42191.1 - 0.061 13.6 0.0 5.3 7.4 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 CBY42191.1 - 0.068 12.3 0.0 4.8 6.2 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Septin PF00735.18 CBY42191.1 - 0.069 12.4 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 CBY42191.1 - 0.084 12.9 0.3 24 5.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CBY42191.1 - 0.19 11.9 0.3 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBY42191.1 - 0.21 11.9 0.5 1.8 8.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBY42191.1 - 1.4 9.1 3.1 16 5.6 0.1 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CBY42191.1 - 1.5 8.7 4.4 51 3.7 0.1 3.9 2 1 2 4 4 4 0 NTPase Fer4_4 PF12800.7 CBY42191.1 - 2.9 8.6 14.8 0.17 12.4 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CBY42191.1 - 3.7 8.1 11.3 0.36 11.3 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 CBY42191.1 - 3.8 8.1 11.3 0.12 13.0 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain MRP-S34 PF16053.5 CBY42192.1 - 5.3e-10 39.0 0.0 7e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S34 WD40 PF00400.32 CBY42193.1 - 9.1e-37 124.4 11.3 2.5e-06 28.1 0.1 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY42193.1 - 8.1e-16 58.1 9.6 0.0054 17.0 0.0 7.4 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY42193.1 - 4.2e-06 26.3 0.9 0.018 14.4 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBY42193.1 - 0.0057 15.4 2.6 0.077 11.6 0.0 3.6 3 1 1 5 5 5 1 Nucleoporin Nup120/160 DUF2956 PF11169.8 CBY42193.1 - 0.041 14.1 1.1 0.08 13.1 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) dsrm PF00035.26 CBY42194.1 - 1.9e-18 66.9 5.6 1.1e-06 29.2 0.1 4.8 4 0 0 4 4 4 3 Double-stranded RNA binding motif R3H PF01424.22 CBY42194.1 - 6.1e-09 35.7 0.0 2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 CBY42194.1 - 0.0013 18.6 3.7 0.0022 17.8 2.4 2.0 2 0 0 2 2 2 1 G-patch domain TRP_2 PF08344.11 CBY42195.1 - 3e-22 78.6 1.5 6.2e-22 77.6 1.5 1.6 1 0 0 1 1 1 1 Transient receptor ion channel II Ank_2 PF12796.7 CBY42195.1 - 1.3e-09 38.5 0.1 8.8e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY42195.1 - 6.8e-07 29.1 1.7 2 9.2 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 CBY42195.1 - 0.00047 20.7 0.0 0.045 14.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY42195.1 - 0.0065 16.9 0.1 0.42 11.1 0.1 3.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CBY42195.1 - 0.013 15.8 0.0 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Fimbrial_CS1 PF04449.12 CBY42196.1 - 0.052 13.7 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 CS1 type fimbrial major subunit Relaxase PF03432.14 CBY42196.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Acetyltransf_10 PF13673.7 CBY42198.1 - 1.3e-05 25.2 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY42198.1 - 6.6e-05 23.1 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY42198.1 - 0.00024 21.5 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY42198.1 - 0.02 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CBY42198.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GAGE PF05831.11 CBY42199.1 - 0.076 13.6 4.3 0.2 12.2 0.8 2.7 1 1 1 2 2 2 0 GAGE protein Fic_N PF13784.6 CBY42199.1 - 0.086 12.9 0.1 0.29 11.2 0.1 1.9 1 0 0 1 1 1 0 Fic/DOC family N-terminal CEP209_CC5 PF16574.5 CBY42200.1 - 3.3e-34 117.8 14.7 3.3e-34 117.8 14.7 6.2 3 2 2 6 6 6 2 Coiled-coil region of centrosome protein CE290 TPR_MLP1_2 PF07926.12 CBY42200.1 - 0.00033 20.7 10.4 0.00033 20.7 10.4 7.9 3 2 3 7 7 7 1 TPR/MLP1/MLP2-like protein Ephrin_rec_like PF07699.13 CBY42201.1 - 0.0093 15.7 7.8 0.0093 15.7 7.8 9.9 4 4 5 9 9 9 5 Putative ephrin-receptor like TRM13 PF05206.14 CBY42202.1 - 3.6e-50 170.9 5.2 1.4e-49 169.0 1.7 2.8 2 1 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CBY42202.1 - 1.2e-10 41.0 4.3 1.2e-10 41.0 4.3 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_31 PF13847.6 CBY42202.1 - 0.00031 20.6 0.1 0.0007 19.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBY42202.1 - 0.00078 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CBY42202.1 - 0.0016 18.5 7.4 0.0051 16.8 7.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF4416 PF14385.6 CBY42202.1 - 0.0031 17.4 0.5 0.0088 16.0 0.2 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4416) Sgf11 PF08209.11 CBY42202.1 - 0.014 15.0 0.7 0.032 13.8 0.7 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) FtsJ PF01728.19 CBY42202.1 - 0.035 14.2 0.0 0.45 10.6 0.0 2.3 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 CBY42202.1 - 0.07 13.9 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 CBY42203.1 - 4e-38 131.3 0.1 5.9e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42203.1 - 1.6e-19 70.3 0.0 5.9e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LisH PF08513.11 CBY42204.1 - 9.1e-06 25.5 0.3 5.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 LisH HEAT PF02985.22 CBY42204.1 - 1.1e-05 25.2 6.8 0.00046 20.2 0.1 5.4 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CBY42204.1 - 0.006 16.6 1.2 0.065 13.3 0.5 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBY42204.1 - 0.011 16.1 3.6 0.029 14.7 0.2 3.2 3 1 0 4 4 4 0 HEAT repeats DASH_Ask1 PF08655.10 CBY42204.1 - 0.02 14.7 3.9 0.12 12.3 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Ask1 Golgin_A5 PF09787.9 CBY42206.1 - 0.046 13.2 41.9 0.058 12.8 21.5 2.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Filament PF00038.21 CBY42206.1 - 0.14 11.7 38.4 0.19 11.3 38.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein SHE3 PF17078.5 CBY42206.1 - 0.23 11.2 32.8 2.1 8.0 2.4 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF2389 PF09493.10 CBY42206.1 - 0.45 11.2 3.7 14 6.4 3.7 2.8 1 1 0 1 1 1 0 Tryptophan-rich protein (DUF2389) DUF2353 PF09789.9 CBY42206.1 - 1.1 8.5 38.3 0.85 8.9 8.1 2.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF724 PF05266.14 CBY42206.1 - 1.3 8.8 36.2 2 8.2 15.3 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Uso1_p115_C PF04871.13 CBY42206.1 - 1.6 9.1 41.1 0.042 14.2 5.6 3.4 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 CBY42206.1 - 1.8 8.6 21.5 1.3 9.1 1.7 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 CBY42206.1 - 1.8 8.8 37.4 1.1 9.6 3.2 4.1 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin PF00261.20 CBY42206.1 - 2.7 7.3 41.3 0.73 9.2 13.6 2.1 1 1 1 2 2 2 0 Tropomyosin Fez1 PF06818.15 CBY42206.1 - 3.2 8.2 38.0 1.7e+02 2.6 38.0 2.2 1 1 0 1 1 1 0 Fez1 DUF3800 PF12686.7 CBY42206.1 - 4.8 7.8 8.7 61 4.3 8.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) LPP PF04728.13 CBY42206.1 - 5.8 7.4 15.5 3.8 8.0 0.2 5.0 3 3 2 5 5 5 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 CBY42206.1 - 6.6 6.8 44.4 0.031 14.3 22.6 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CBY42206.1 - 6.8 5.9 29.4 68 2.7 11.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 CBY42206.1 - 7 6.7 49.3 3.2 7.8 7.0 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Vac_Fusion PF02346.16 CBY42206.1 - 9.4 5.9 12.5 0.22 11.2 1.2 3.2 3 1 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Aminotran_1_2 PF00155.21 CBY42207.1 - 2.8e-32 112.3 0.0 3.1e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CBY42207.1 - 2.2e-06 26.6 0.0 2.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Bacteriocin_IIc PF10439.9 CBY42207.1 - 0.044 13.9 0.1 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DegT_DnrJ_EryC1 PF01041.17 CBY42207.1 - 0.062 12.6 0.2 0.076 12.3 0.2 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CBY42207.1 - 0.15 11.3 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Guanylate_kin PF00625.21 CBY42208.1 - 8.1e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase SH3_1 PF00018.28 CBY42208.1 - 0.0048 16.5 0.3 0.029 14.0 0.1 2.2 2 0 0 2 2 2 1 SH3 domain VGCC_beta4Aa_N PF12052.8 CBY42208.1 - 0.16 12.1 4.7 0.22 11.7 1.5 2.3 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal SVWC PF15430.6 CBY42209.1 - 0.063 13.6 4.3 4.8 7.5 0.2 2.4 2 0 0 2 2 2 0 Single domain von Willebrand factor type C THP2 PF09432.10 CBY42209.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Tho complex subunit THP2 Med7 PF05983.11 CBY42211.1 - 1.8e-37 129.3 3.7 6.2e-37 127.5 3.7 1.7 1 1 0 1 1 1 1 MED7 protein UQ_con PF00179.26 CBY42212.1 - 3.5e-11 42.9 0.1 5.4e-10 39.1 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme adh_short PF00106.25 CBY42213.1 - 1.6e-09 37.5 1.4 6e-09 35.6 1.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CBY42213.1 - 2.5e-08 33.7 0.5 6.6e-08 32.3 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CBY42213.1 - 4.5e-07 29.7 0.5 8.9e-07 28.7 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 CBY42213.1 - 0.00073 18.7 0.2 0.0012 18.0 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBY42213.1 - 0.0045 16.9 0.7 0.0062 16.4 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY42213.1 - 0.022 14.2 0.4 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Lectin_C PF00059.21 CBY42216.1 - 3.6e-13 50.2 5.3 1.5e-11 44.9 0.2 2.9 3 0 0 3 3 3 2 Lectin C-type domain T4_deiodinase PF00837.17 CBY42217.1 - 2.7e-27 95.6 0.0 3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Choline_kinase PF01633.20 CBY42219.1 - 1.9e-08 34.2 0.1 2.9e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBY42219.1 - 2.2e-07 31.1 0.0 3.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CBY42219.1 - 0.01 15.1 1.6 0.011 15.0 0.5 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Integrin_alpha2 PF08441.12 CBY42221.1 - 7.3e-47 160.3 0.6 2.7e-46 158.4 0.6 1.7 1 1 0 1 1 1 1 Integrin alpha FG-GAP PF01839.23 CBY42221.1 - 8.6e-15 54.6 22.3 7e-08 32.5 7.1 4.8 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 CBY42221.1 - 7.3e-11 42.5 4.7 0.00018 22.0 0.3 4.1 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF11 PF01345.18 CBY42221.1 - 0.085 13.2 0.1 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF11 WD40 PF00400.32 CBY42222.1 - 0.00067 20.4 0.5 0.0026 18.6 0.2 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat DEAD PF00270.29 CBY42223.1 - 3.1e-32 111.8 0.0 5.4e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY42223.1 - 1.6e-20 73.5 0.0 5.6e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY42223.1 - 0.00026 21.0 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CBY42223.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 CBY42223.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.6 CBY42226.1 - 0.041 14.3 0.2 0.08 13.3 0.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DCX PF03607.17 CBY42229.1 - 1.4e-12 47.5 0.1 1e-07 31.9 0.0 2.4 2 0 0 2 2 2 2 Doublecortin KH_dom-like PF14714.6 CBY42229.1 - 0.081 13.3 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Connexin43 PF03508.13 CBY42229.1 - 0.23 11.1 0.9 0.51 9.9 0.9 1.6 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) UBD PF16455.5 CBY42231.1 - 9.3e-30 103.0 0.4 3.4e-29 101.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-binding domain ubiquitin PF00240.23 CBY42231.1 - 1.1e-10 41.1 0.1 2.1e-10 40.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBY42231.1 - 0.0028 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like NAM-associated PF14303.6 CBY42233.1 - 0.032 14.9 7.2 0.069 13.9 7.2 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Vfa1 PF08432.10 CBY42233.1 - 2.7 8.3 9.2 4.5 7.6 9.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Alk_phosphatase PF00245.20 CBY42234.1 - 1.5e-119 399.6 0.1 1.9e-119 399.3 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CBY42234.1 - 0.015 14.6 0.0 0.052 12.9 0.0 2.1 1 1 0 1 1 1 0 Metalloenzyme superfamily NCBP3 PF10309.9 CBY42234.1 - 0.018 14.9 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 OST3_OST6 PF04756.13 CBY42235.1 - 0.016 14.6 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family PX PF00787.24 CBY42237.1 - 0.00061 19.7 0.1 0.0018 18.2 0.0 1.9 2 0 0 2 2 2 1 PX domain SNX17_FERM_C PF18116.1 CBY42237.1 - 0.014 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain HSP70 PF00012.20 CBY42238.1 - 3.5e-21 75.1 4.4 1.2e-18 66.7 0.5 2.1 1 1 1 2 2 2 2 Hsp70 protein FGGY_C PF02782.16 CBY42238.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.6 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain ELP6 PF09807.9 CBY42242.1 - 0.00085 18.8 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Elongation complex protein 6 Cytidylate_kin PF02224.18 CBY42242.1 - 0.02 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase ClpB_D2-small PF10431.9 CBY42245.1 - 1.6e-08 34.5 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Yip1 PF04893.17 CBY42246.1 - 0.008 15.9 0.2 0.0096 15.7 0.2 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3860 PF12976.7 CBY42247.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) EGF_CA PF07645.15 CBY42248.1 - 2.1e-47 159.0 203.6 1.5e-09 37.9 8.1 16.6 12 4 3 15 15 15 11 Calcium-binding EGF domain cEGF PF12662.7 CBY42248.1 - 3.9e-16 58.7 120.9 3.1e-07 30.2 2.1 14.0 11 2 0 11 11 11 8 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY42248.1 - 4.1e-15 55.8 40.4 1.8e-08 34.5 10.3 13.6 14 2 1 15 15 15 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY42248.1 - 4.2e-06 27.0 30.0 0.00017 21.8 8.3 16.5 14 2 3 17 17 17 7 EGF-like domain hEGF PF12661.7 CBY42248.1 - 0.013 16.1 5.5 0.013 16.1 5.5 16.8 17 2 0 17 17 17 0 Human growth factor-like EGF EGF_3 PF12947.7 CBY42248.1 - 0.013 15.7 9.3 0.013 15.7 9.3 15.0 13 3 3 16 16 16 0 EGF domain Rad60-SLD PF11976.8 CBY42249.1 - 0.05 13.4 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TipAS PF07739.13 CBY42249.1 - 0.18 12.4 2.1 1.8 9.1 0.1 2.6 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Lysozyme_like PF13702.6 CBY42250.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Lysozyme-like Aminotran_1_2 PF00155.21 CBY42251.1 - 1.7e-11 43.9 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Preseq_ALAS PF09029.10 CBY42251.1 - 0.0011 19.4 0.3 0.0027 18.2 0.3 1.7 1 1 0 1 1 1 1 5-aminolevulinate synthase presequence ARPC4 PF05856.12 CBY42252.1 - 9.1e-74 246.6 6.3 1e-73 246.5 6.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Val_tRNA-synt_C PF10458.9 CBY42254.1 - 2.5e-06 27.7 5.9 3.8e-06 27.1 5.4 1.6 1 1 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm DUF724 PF05266.14 CBY42254.1 - 0.028 14.2 1.8 0.031 14.1 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Curto_V2 PF07325.11 CBY42254.1 - 0.037 13.9 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 Curtovirus V2 protein TMPIT PF07851.13 CBY42254.1 - 0.095 11.9 2.3 0.11 11.8 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein COG2 PF06148.11 CBY42254.1 - 0.15 12.2 3.8 0.74 9.9 3.8 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ANTH PF07651.16 CBY42255.1 - 1.3e-43 149.0 0.1 1.3e-43 149.0 0.1 1.9 2 0 0 2 2 2 1 ANTH domain GAS PF13851.6 CBY42255.1 - 0.41 10.0 26.4 0.081 12.3 18.8 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding VWD PF00094.25 CBY42257.1 - 1.1e-22 81.0 1.8 2.2e-22 80.0 1.8 1.5 1 0 0 1 1 1 1 von Willebrand factor type D domain C8 PF08742.11 CBY42257.1 - 1.8e-17 63.5 25.6 3.9e-14 52.8 11.5 4.5 4 1 1 5 5 5 2 C8 domain TIL PF01826.17 CBY42257.1 - 0.00052 20.2 9.1 0.00052 20.2 9.1 7.1 6 3 1 7 7 7 1 Trypsin Inhibitor like cysteine rich domain Ribosomal_S9 PF00380.19 CBY42259.1 - 3.1e-32 111.6 0.6 3.5e-32 111.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.19 CBY42260.1 - 3.6e-13 50.0 0.4 3.6e-13 50.0 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CBY42260.1 - 1.4e-06 28.4 6.3 1.4e-06 28.4 6.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain ProRS-C_1 PF09180.11 CBY42261.1 - 1e-18 67.3 1.0 2.8e-18 65.9 1.0 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CBY42261.1 - 7.2e-18 64.5 0.1 2.8e-16 59.4 0.0 2.8 2 1 1 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBY42261.1 - 1.1e-16 61.4 0.0 1.9e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HMA PF00403.26 CBY42263.1 - 1e-25 89.9 6.2 1.4e-11 44.7 0.1 3.3 3 0 0 3 3 3 3 Heavy-metal-associated domain Fer2_BFD PF04324.15 CBY42263.1 - 0.0015 18.8 2.5 0.71 10.3 0.1 3.6 4 0 0 4 4 4 1 BFD-like [2Fe-2S] binding domain Fer4_13 PF13370.6 CBY42263.1 - 0.022 15.3 1.6 3.7 8.2 0.0 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Pox_A3L PF05288.11 CBY42263.1 - 0.17 11.9 1.1 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A3L Protein zf-C3HC4_4 PF15227.6 CBY42263.1 - 0.21 11.8 4.0 11 6.2 0.1 3.1 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING LRR_4 PF12799.7 CBY42264.1 - 4.8e-24 84.0 28.4 0.00028 21.2 0.2 7.2 6 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY42264.1 - 2.5e-18 65.6 21.7 7.5e-09 35.2 6.0 6.2 4 1 2 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 CBY42264.1 - 4.9e-14 52.2 14.5 7.7e-06 25.5 2.3 4.0 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBY42264.1 - 3.2e-06 26.8 19.0 2.4 8.4 0.3 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 CBY42264.1 - 0.091 13.4 17.4 42 5.3 0.4 7.7 6 2 0 6 6 6 0 Leucine Rich Repeat Carbpep_Y_N PF05388.11 CBY42264.1 - 0.17 12.4 2.0 0.22 12.0 0.3 2.2 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide INPP5B_PH PF16776.5 CBY42266.1 - 0.079 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Collagen PF01391.18 CBY42267.1 - 1.6e-18 66.2 81.8 5.2e-08 32.5 27.3 3.5 2 1 2 4 4 4 3 Collagen triple helix repeat (20 copies) CUB PF00431.20 CBY42268.1 - 5.2e-10 39.6 0.0 8.6e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 CUB domain DAO PF01266.24 CBY42269.1 - 1.3e-40 140.1 0.0 1.5e-40 139.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBY42269.1 - 2.8e-06 26.8 1.9 0.0023 17.2 0.1 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBY42269.1 - 0.00019 20.3 2.0 0.008 14.9 0.2 2.5 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 CBY42269.1 - 0.00034 19.8 0.2 0.02 14.0 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBY42269.1 - 0.00045 20.4 0.5 0.00045 20.4 0.5 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CBY42269.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBY42269.1 - 0.0014 18.0 0.2 0.0054 16.0 0.2 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBY42269.1 - 0.0014 17.8 0.6 0.0051 15.9 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 CBY42269.1 - 0.0093 15.2 0.2 0.017 14.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CBY42269.1 - 0.042 14.4 0.3 0.042 14.4 0.3 3.1 5 0 0 5 5 4 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CBY42269.1 - 0.066 12.8 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EF-hand_1 PF00036.32 CBY42270.1 - 2.2e-13 48.7 20.8 0.00045 19.6 0.5 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBY42270.1 - 2.6e-12 45.6 17.5 0.0023 17.7 0.6 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBY42270.1 - 5.9e-12 45.9 16.0 0.0001 22.7 5.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CBY42270.1 - 9.7e-05 22.1 18.0 0.27 11.1 0.2 5.5 6 0 0 6 6 6 3 EF-hand domain pair DUF2179 PF10035.9 CBY42270.1 - 0.068 12.9 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Spc7_N PF15402.6 CBY42270.1 - 0.084 11.1 0.8 0.11 10.7 0.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SPARC_Ca_bdg PF10591.9 CBY42270.1 - 0.12 12.7 16.2 5 7.5 0.2 4.0 1 1 3 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1140 PF06600.11 CBY42270.1 - 0.25 11.8 3.9 0.14 12.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) EF-hand_5 PF13202.6 CBY42270.1 - 0.29 10.7 17.3 6.9 6.4 0.6 4.8 5 0 0 5 5 5 0 EF hand EF-hand_10 PF14788.6 CBY42270.1 - 2.1 8.3 10.7 0.66 9.9 2.0 3.7 4 0 0 4 4 4 0 EF hand DnaJ PF00226.31 CBY42272.1 - 3.7e-13 49.4 1.6 3.7e-13 49.4 1.6 3.8 3 1 1 4 4 4 1 DnaJ domain WD40 PF00400.32 CBY42273.1 - 7.1e-40 134.3 16.9 1.8e-08 34.9 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY42273.1 - 2.4e-11 43.8 0.1 0.0066 16.7 0.0 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY42273.1 - 3.7e-06 26.5 0.0 0.0038 16.6 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CBY42273.1 - 0.00062 18.5 1.0 9.6 4.7 0.0 3.9 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBY42273.1 - 0.00068 18.7 0.0 2.1 7.2 0.0 3.2 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CBY42273.1 - 0.0069 15.0 0.0 2.7 6.4 0.1 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain mRNA_stabil PF13929.6 CBY42273.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 mRNA stabilisation PD40 PF07676.12 CBY42273.1 - 0.22 11.5 3.0 46 4.1 0.1 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat FA_desaturase PF00487.24 CBY42275.1 - 3.7 7.3 9.1 0.31 10.8 1.5 2.0 1 1 1 2 2 2 0 Fatty acid desaturase DnaJ PF00226.31 CBY42277.1 - 3.9e-08 33.3 0.1 7.9e-06 25.9 0.1 3.4 2 1 0 2 2 2 1 DnaJ domain Hid1 PF12722.7 CBY42277.1 - 0.027 12.6 1.4 0.036 12.2 1.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RPT PF13446.6 CBY42277.1 - 0.037 14.0 0.1 0.098 12.6 0.0 1.8 2 0 0 2 2 2 0 A repeated domain in UCH-protein Erythro_esteras PF05139.14 CBY42277.1 - 0.065 13.0 1.9 0.1 12.4 1.9 1.3 1 0 0 1 1 1 0 Erythromycin esterase DUF3080 PF11279.8 CBY42277.1 - 0.18 11.0 2.6 0.28 10.3 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) DUF1943 PF09172.11 CBY42277.1 - 0.3 10.3 2.6 0.43 9.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cgr1 PF03879.14 CBY42277.1 - 3.7 8.0 17.9 0.84 10.0 12.0 2.3 2 0 0 2 2 2 0 Cgr1 family Tetraspanin PF00335.20 CBY42278.1 - 3.9e-08 33.3 1.2 1.7e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 Tetraspanin family Nup160 PF11715.8 CBY42279.1 - 4.3e-05 22.4 0.1 4.5e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.32 CBY42279.1 - 0.00016 22.4 0.3 0.17 12.8 0.1 3.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Kelch_5 PF13854.6 CBY42281.1 - 0.0082 16.1 4.8 0.087 12.8 0.0 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 CBY42281.1 - 0.077 13.3 8.0 21 5.6 0.0 4.5 4 1 1 5 5 5 0 Kelch motif Kelch_4 PF13418.6 CBY42281.1 - 0.12 12.4 2.5 6 7.0 0.0 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY42281.1 - 0.23 11.5 5.5 5.6 7.1 0.0 3.8 4 0 0 4 4 4 0 Kelch motif zf-RING_5 PF14634.6 CBY42282.1 - 7e-05 22.7 13.6 7.4e-05 22.6 9.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain FYVE PF01363.21 CBY42282.1 - 0.0002 21.4 6.8 0.00061 19.9 6.8 1.8 1 1 0 1 1 1 1 FYVE zinc finger zf-C3HC4 PF00097.25 CBY42282.1 - 0.00091 19.0 7.7 0.00091 19.0 7.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY42282.1 - 0.0082 16.5 9.0 0.0082 16.5 9.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 CBY42282.1 - 0.0087 15.8 5.0 0.0087 15.8 5.0 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CBY42282.1 - 0.013 15.5 6.6 0.013 15.5 6.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Spc7 PF08317.11 CBY42282.1 - 0.16 10.8 14.3 0.26 10.1 14.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein NBP1 PF08537.10 CBY42282.1 - 1.2 8.4 14.2 3.3 7.0 14.2 1.6 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 zf-C3HC4_2 PF13923.6 CBY42282.1 - 5.5 6.9 16.3 0.098 12.5 8.2 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RabGAP-TBC PF00566.18 CBY42283.1 - 9.7e-38 130.0 0.1 1.3e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PDR_assoc PF08370.11 CBY42283.1 - 0.27 11.0 1.0 0.91 9.3 0.0 2.4 2 1 1 3 3 3 0 Plant PDR ABC transporter associated HIP1_clath_bdg PF16515.5 CBY42284.1 - 0.0034 18.0 12.9 0.0034 18.0 12.9 4.9 1 1 4 5 5 5 1 Clathrin-binding domain of Huntingtin-interacting protein 1 C12orf66_like PF09404.10 CBY42284.1 - 0.013 14.4 0.5 0.013 14.4 0.5 1.9 2 1 1 3 3 3 0 KICSTOR complex C12orf66 like Golgin_A5 PF09787.9 CBY42284.1 - 1.4 8.3 58.7 0.41 10.1 38.3 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 ERM PF00769.19 CBY42284.1 - 9.6 5.9 68.2 4.4 7.1 34.2 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family rve PF00665.26 CBY42288.1 - 2.6e-21 76.0 0.0 4.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY42288.1 - 1e-14 54.4 0.0 2.9e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 CBY42288.1 - 0.0035 17.1 0.1 0.0066 16.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain ETC_C1_NDUFA5 PF04716.14 CBY42289.1 - 1.2e-12 47.4 0.1 2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Fer2 PF00111.27 CBY42290.1 - 5.2e-07 29.5 0.8 8.8e-07 28.8 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nicastrin PF05450.15 CBY42291.1 - 0.056 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Nicastrin WD40 PF00400.32 CBY42292.1 - 0.0079 17.0 0.2 0.0098 16.7 0.2 1.1 1 0 0 1 1 1 1 WD domain, G-beta repeat RNA_pol_A_bac PF01000.26 CBY42293.1 - 7.6e-20 71.4 1.6 9.4e-19 67.8 0.2 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBY42293.1 - 6.2e-19 67.2 0.0 1.3e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Epimerase PF01370.21 CBY42294.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY42294.1 - 0.005 16.8 0.0 0.021 14.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CBY42294.1 - 0.012 15.0 0.2 0.026 13.9 0.1 1.7 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 CBY42294.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 CBY42294.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Nicastrin PF05450.15 CBY42296.1 - 2.5e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 CBY42296.1 - 3.5e-05 23.6 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 RNA_pol_Rpb2_2 PF04561.14 CBY42296.1 - 0.044 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Fer2 PF00111.27 CBY42297.1 - 5.2e-07 29.5 0.8 8.8e-07 28.8 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ETC_C1_NDUFA5 PF04716.14 CBY42298.1 - 9.2e-13 47.8 0.1 1.5e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3361 PF11841.8 CBY42299.1 - 0.04 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Foie-gras_1 PF11817.8 CBY42300.1 - 1.9e-18 67.0 0.3 3.5e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Spo0M PF07070.11 CBY42300.1 - 0.085 12.4 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 SpoOM protein E1_DerP2_DerF2 PF02221.15 CBY42300.1 - 0.098 13.1 0.3 5 7.6 0.3 2.4 2 0 0 2 2 2 0 ML domain CTP_transf_like PF01467.26 CBY42302.1 - 1.1e-36 126.2 0.1 5.9e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CBY42302.1 - 2.9 7.8 5.6 2.9 7.8 0.6 2.8 2 1 0 2 2 2 0 FAD synthetase Gly_transf_sug PF04488.15 CBY42303.1 - 7.4e-10 39.3 0.2 9.6e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CBY42303.1 - 0.038 13.3 1.1 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain NYAP_N PF15439.6 CBY42304.1 - 0.026 13.7 2.6 0.028 13.6 2.6 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Cwf_Cwc_15 PF04889.12 CBY42304.1 - 1.8 8.3 14.9 2 8.1 14.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RYDR_ITPR PF01365.21 CBY42305.1 - 1.7e-51 174.5 8.0 4.3e-51 173.2 8.0 1.7 1 0 0 1 1 1 1 RIH domain MIR PF02815.19 CBY42305.1 - 1.4e-48 165.2 0.1 5.6e-48 163.3 0.0 2.1 2 0 0 2 2 2 1 MIR domain Lectin_C PF00059.21 CBY42306.1 - 1.9e-05 25.3 0.0 2.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Lectin C-type domain Pkinase_Tyr PF07714.17 CBY42308.1 - 7.6e-08 31.9 0.0 8.9e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase COX5A PF02284.16 CBY42308.1 - 0.056 13.5 0.1 0.3 11.1 0.0 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va HSP90 PF00183.18 CBY42309.1 - 2.3e-142 475.5 14.1 1.7e-135 452.9 8.6 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 CBY42309.1 - 1.6e-12 47.9 0.1 3.3e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBY42309.1 - 2.3e-09 37.2 0.1 5.5e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pecanex_C PF05041.15 CBY42310.1 - 3.8e-52 177.1 0.1 7.5e-52 176.2 0.1 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Kunitz_BPTI PF00014.23 CBY42311.1 - 4.6e-16 58.8 1.5 5.1e-16 58.6 1.5 1.0 1 0 0 1 1 1 1 Kunitz/Bovine pancreatic trypsin inhibitor domain TRAM_LAG1_CLN8 PF03798.16 CBY42312.1 - 1e-11 45.0 11.8 1.3e-11 44.6 11.8 1.2 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 CBY42313.1 - 2.6e-05 24.0 4.6 3.1e-05 23.8 4.6 1.1 1 0 0 1 1 1 1 TLC domain DUF4850 PF16142.5 CBY42313.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) PLAC8 PF04749.17 CBY42314.1 - 1.8e-12 48.1 7.3 2.5e-12 47.7 7.3 1.2 1 0 0 1 1 1 1 PLAC8 family Arm PF00514.23 CBY42315.1 - 1e-13 50.8 4.7 1.2e-06 28.4 0.1 5.3 5 1 1 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBY42315.1 - 0.019 15.4 0.1 0.6 10.7 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 CBY42315.1 - 0.07 13.5 0.2 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 HEAT repeats DUF4298 PF14131.6 CBY42315.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Nrap_D6 PF17407.2 CBY42316.1 - 0.00023 21.4 0.2 0.00052 20.2 0.2 1.5 1 1 0 1 1 1 1 Nrap protein domain 6 PALP PF00291.25 CBY42317.1 - 7.7e-72 242.2 0.5 8.5e-72 242.0 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.24 CBY42317.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain WWE PF02825.20 CBY42318.1 - 1.7e-13 50.9 4.1 2.2e-13 50.6 4.1 1.2 1 0 0 1 1 1 1 WWE domain zf-C3HC4 PF00097.25 CBY42318.1 - 1.4e-08 34.5 6.3 2.1e-08 33.9 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY42318.1 - 1.8e-08 34.1 3.5 2.4e-08 33.7 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY42318.1 - 9.4e-08 32.3 7.5 1.4e-07 31.7 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY42318.1 - 1.1e-07 31.5 8.6 1.7e-07 31.0 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY42318.1 - 5.5e-07 29.6 11.1 8.3e-07 29.1 11.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBY42318.1 - 7.2e-06 25.9 12.0 1.1e-05 25.3 5.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY42318.1 - 8.4e-05 22.5 5.6 0.00018 21.4 5.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBY42318.1 - 0.00035 20.4 11.4 0.011 15.6 11.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 CBY42318.1 - 0.011 15.9 3.6 0.041 14.1 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon UBZ_FAAP20 PF15750.5 CBY42318.1 - 0.036 14.0 2.5 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-ANAPC11 PF12861.7 CBY42318.1 - 0.049 13.7 2.2 0.11 12.6 2.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY42318.1 - 0.052 13.3 6.3 0.37 10.6 6.5 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 CBY42318.1 - 0.098 13.1 3.9 0.46 11.0 0.2 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 CBY42318.1 - 0.19 11.9 3.9 0.34 11.1 3.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 CBY42318.1 - 0.24 11.2 6.8 1.2 8.9 6.8 2.1 1 1 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CBY42318.1 - 0.37 11.1 8.1 2.8 8.3 8.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain GAGA PF09237.11 CBY42318.1 - 0.44 10.4 3.6 0.64 9.9 0.3 2.3 2 0 0 2 2 2 0 GAGA factor PAP_assoc PF03828.19 CBY42319.1 - 6.4e-14 51.9 0.0 2.1e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase EF-hand_7 PF13499.6 CBY42323.1 - 2.8e-07 30.9 0.4 3.3e-07 30.6 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY42323.1 - 5e-06 25.7 0.5 0.0072 15.8 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CBY42323.1 - 8e-06 25.1 1.5 0.00059 19.2 0.4 2.6 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBY42323.1 - 4e-05 23.2 0.3 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain RepB-RCR_reg PF10723.9 CBY42323.1 - 0.021 14.7 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB EF-hand_8 PF13833.6 CBY42323.1 - 0.061 13.2 0.1 0.83 9.6 0.1 2.1 1 1 0 1 1 1 0 EF-hand domain pair Kelch_2 PF07646.15 CBY42325.1 - 0.12 12.4 1.4 13 6.0 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 CBY42325.1 - 0.29 11.2 4.0 0.32 11.0 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY42327.1 - 1.5e-07 31.5 12.8 0.14 12.5 0.1 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBY42327.1 - 3.4e-06 26.8 11.0 0.81 9.8 0.0 7.5 7 0 0 7 7 7 2 Kelch motif Kelch_1 PF01344.25 CBY42327.1 - 0.00016 21.2 15.0 1 9.0 0.0 7.1 8 0 0 8 8 8 3 Kelch motif Kelch_5 PF13854.6 CBY42327.1 - 0.0057 16.6 19.2 4.6 7.3 0.0 7.1 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 CBY42327.1 - 6.3 6.9 24.1 3.2 7.8 0.1 6.6 8 0 0 8 8 8 0 Galactose oxidase, central domain Exo70 PF03081.15 CBY42328.1 - 0.013 14.6 0.2 0.038 13.0 0.0 1.8 2 0 0 2 2 2 0 Exo70 exocyst complex subunit Vps52 PF04129.12 CBY42328.1 - 0.051 12.3 0.3 0.078 11.7 0.3 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family PHO4 PF01384.20 CBY42329.1 - 0.021 13.9 0.5 0.025 13.6 0.5 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF1275 PF06912.11 CBY42329.1 - 0.027 14.4 2.0 0.032 14.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) SBF PF01758.16 CBY42330.1 - 1.9e-27 96.2 14.7 2.4e-27 95.9 14.7 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 CBY42330.1 - 1.4e-10 41.0 11.8 1.8e-10 40.6 11.8 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.18 CBY42330.1 - 0.45 8.8 13.5 0.21 10.0 10.5 1.7 1 1 1 2 2 2 0 Membrane transport protein CBP_BcsF PF11120.8 CBY42330.1 - 0.77 9.9 4.1 0.55 10.4 0.7 2.3 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF TssN PF17555.2 CBY42330.1 - 6 6.2 8.2 7.9 5.8 8.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2627 PF11118.8 CBY42331.1 - 0.34 11.5 4.7 0.14 12.7 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) VIT1 PF01988.19 CBY42331.1 - 8.6 6.2 6.6 3 7.6 1.8 2.3 1 1 2 3 3 3 0 VIT family rve PF00665.26 CBY42333.1 - 2.5e-17 63.1 0.0 6.9e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY42333.1 - 2.6e-16 59.5 0.1 4.8e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CBY42333.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger MLVIN_C PF18697.1 CBY42333.1 - 0.014 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain EF-hand_10 PF14788.6 CBY42333.1 - 0.02 14.7 0.2 2.1 8.3 0.0 2.8 2 0 0 2 2 2 0 EF hand rve_3 PF13683.6 CBY42333.1 - 0.036 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain TTKRSYEDQ PF10212.9 CBY42334.1 - 2.3e-07 30.2 13.2 2.3e-07 30.2 13.2 1.9 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF948 PF06103.11 CBY42334.1 - 1.4 9.2 7.4 13 6.1 0.4 3.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YscO-like PF16789.5 CBY42334.1 - 5.5 7.0 19.4 0.83 9.7 1.4 2.4 2 0 0 2 2 2 0 YscO-like protein Filament PF00038.21 CBY42337.1 - 6.1e-22 78.6 13.7 7.4e-22 78.3 13.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 CBY42337.1 - 0.018 15.3 7.9 0.056 13.7 1.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2721 PF11026.8 CBY42337.1 - 1.8 8.5 2.7 1.2 9.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DivIC PF04977.15 CBY42337.1 - 2.1 8.2 10.7 3.9 7.3 2.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 CBY42337.1 - 4.8 6.2 10.7 5.6 6.0 10.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 CBY42338.1 - 4.7e-17 62.3 0.0 6.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Toluene_X PF03349.16 CBY42340.1 - 0.027 13.1 3.2 0.04 12.5 0.3 1.9 1 1 1 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) TSP_1 PF00090.19 CBY42340.1 - 0.8 10.0 12.7 3.1 8.1 0.1 2.8 2 1 0 2 2 2 0 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY42341.1 - 2.6e-07 30.7 2.1 2.6e-07 30.7 2.1 3.7 2 1 1 3 3 3 2 Thrombospondin type 1 domain Chlam_PMP PF02415.17 CBY42343.1 - 0.057 13.9 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NDK PF00334.19 CBY42344.1 - 5.1e-44 149.6 0.0 6.9e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 CBY42344.1 - 3.4e-13 49.1 0.0 5.8e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif THOC2_N PF16134.5 CBY42345.1 - 2.5e-62 211.4 1.9 3.6e-54 184.5 0.8 4.0 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Helicase_C PF00271.31 CBY42346.1 - 0.00015 22.1 0.2 0.00026 21.3 0.1 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain GST_N_3 PF13417.6 CBY42346.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2922 PF11148.8 CBY42347.1 - 0.0018 17.9 1.4 0.15 11.8 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2922) Peptidase_S55 PF05580.12 CBY42348.1 - 0.072 13.0 1.0 0.09 12.7 1.0 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 CUB PF00431.20 CBY42349.1 - 1.5e-06 28.5 0.1 2.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 CUB domain TPR_2 PF07719.17 CBY42350.1 - 8.2e-31 103.6 2.7 0.045 13.9 0.0 10.8 12 0 0 12 12 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 CBY42350.1 - 6.5e-25 85.9 12.3 0.012 15.5 0.0 11.1 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 CBY42350.1 - 2.7e-23 82.0 7.6 3.7e-05 23.9 0.0 8.1 7 1 3 10 10 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 CBY42350.1 - 1.7e-18 65.2 3.0 0.13 12.4 0.0 8.8 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 CBY42350.1 - 4e-17 61.6 6.5 0.34 11.6 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBY42350.1 - 1.5e-14 52.9 9.9 0.003 17.7 0.0 10.0 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBY42350.1 - 1.6e-14 54.3 2.4 0.0021 18.6 0.0 7.5 5 4 3 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBY42350.1 - 1.6e-14 53.4 2.8 0.4 11.6 0.0 8.5 7 3 4 11 11 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY42350.1 - 4.7e-13 49.4 6.7 0.1 13.1 0.1 7.9 6 3 3 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY42350.1 - 1.9e-12 46.7 8.9 0.0001 21.9 0.0 6.6 8 0 0 8 8 7 2 TPR repeat ANAPC3 PF12895.7 CBY42350.1 - 3.6e-08 33.5 10.9 1.4 9.2 0.0 6.1 5 1 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBY42350.1 - 1.3e-07 31.2 7.3 1.8 8.5 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBY42350.1 - 2.1e-05 23.9 10.7 0.00078 18.7 0.4 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBY42350.1 - 0.00017 21.8 9.5 7.1 7.3 0.1 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY42350.1 - 0.0002 21.4 0.5 4.2 7.6 0.0 4.9 4 1 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 CBY42350.1 - 0.00041 19.5 0.2 0.0026 16.8 0.0 2.4 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3480 PF11979.8 CBY42350.1 - 0.0075 15.3 0.6 0.015 14.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) TPR_20 PF14561.6 CBY42350.1 - 0.0089 16.3 3.5 24 5.4 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBY42350.1 - 0.015 15.4 0.1 38 4.4 0.0 4.0 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat T2SSG PF08334.11 CBY42350.1 - 0.02 14.9 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G DUF2989 PF11207.8 CBY42350.1 - 0.023 14.5 6.5 1.4 8.6 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2989) Hairy_orange PF07527.13 CBY42350.1 - 0.061 13.6 0.0 1.3 9.3 0.0 2.7 3 0 0 3 3 2 0 Hairy Orange BTAD PF03704.17 CBY42350.1 - 0.19 12.2 4.6 26 5.2 0.0 4.5 5 0 0 5 5 4 0 Bacterial transcriptional activator domain DUF4810 PF16068.5 CBY42350.1 - 0.38 11.3 3.0 10 6.8 0.0 4.2 5 0 0 5 5 3 0 Domain of unknown function (DUF4810) rve PF00665.26 CBY42351.1 - 3e-13 50.0 0.0 1e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY42351.1 - 8.6e-09 35.4 0.0 8.6e-09 35.4 0.0 2.8 3 0 0 3 3 3 1 Integrase zinc binding domain zf-H3C2 PF16721.5 CBY42351.1 - 0.0069 16.7 1.2 0.029 14.7 0.1 2.6 3 1 0 3 3 3 1 Zinc-finger like, probable DNA-binding zf-H2C2 PF09337.10 CBY42351.1 - 0.012 15.8 0.3 0.042 14.1 0.3 2.0 1 0 0 1 1 1 0 H2C2 zinc finger cEGF PF12662.7 CBY42353.1 - 1e-06 28.6 0.6 2.7e-06 27.2 0.6 1.8 1 0 0 1 1 1 1 Complement Clr-like EGF-like RANK_CRD_2 PF18278.1 CBY42353.1 - 0.00072 19.7 1.1 0.0021 18.2 1.1 1.8 1 0 0 1 1 1 1 Receptor activator of the NF-KB cysteine-rich repeat domain 2 FXa_inhibition PF14670.6 CBY42353.1 - 0.13 12.6 7.0 0.37 11.1 7.0 1.9 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site DUF4798 PF16055.5 CBY42353.1 - 0.46 10.8 1.9 0.7 10.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) hEGF PF12661.7 CBY42353.1 - 0.88 10.3 6.7 0.15 12.7 2.3 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_CA PF07645.15 CBY42353.1 - 1.4 9.2 15.1 1.1 9.6 5.8 3.0 3 1 0 3 3 3 0 Calcium-binding EGF domain FAIM1 PF06905.13 CBY42354.1 - 1.3e-59 200.8 0.3 1.5e-59 200.6 0.3 1.0 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) Adenyl_transf PF04439.12 CBY42354.1 - 0.079 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Streptomycin adenylyltransferase SET PF00856.28 CBY42355.1 - 1.4e-09 38.6 0.0 3e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 SET domain AIG1 PF04548.16 CBY42355.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AIG1 family zf-RING_5 PF14634.6 CBY42357.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain PDZ PF00595.24 CBY42359.1 - 5.7e-28 97.1 0.0 4.1e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBY42359.1 - 1.8e-22 78.9 0.3 1.4e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 CBY42359.1 - 2.6e-11 43.7 0.0 0.00019 21.7 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CBY42359.1 - 0.027 14.5 0.1 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 CBY42359.1 - 0.18 12.2 0.0 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 PDZ domain YesK PF14150.6 CBY42360.1 - 0.16 12.2 6.1 0.098 12.9 4.1 1.7 2 0 0 2 2 2 0 YesK-like protein Histone_H2A_C PF16211.5 CBY42361.1 - 2e-20 72.2 1.3 4.1e-20 71.2 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY42361.1 - 5.8e-16 59.0 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY42361.1 - 3.8e-05 23.9 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SRP68 PF16969.5 CBY42362.1 - 2.6e-13 49.8 0.5 3.7e-13 49.3 0.5 1.3 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 BRO1 PF03097.18 CBY42362.1 - 0.0025 16.7 4.0 0.0059 15.5 3.8 1.5 1 1 1 2 2 2 1 BRO1-like domain Torsin PF06309.11 CBY42363.1 - 5.9e-25 87.8 0.0 6.9e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.17 CBY42363.1 - 0.0056 16.4 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 CBY42363.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBY42363.1 - 0.018 15.2 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY42363.1 - 0.024 14.6 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY42363.1 - 0.042 14.2 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Adeno_IVa2 PF02456.15 CBY42363.1 - 0.057 12.2 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein VirE PF05272.11 CBY42363.1 - 0.064 13.0 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_7 PF12775.7 CBY42363.1 - 0.068 12.7 0.1 0.098 12.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBY42363.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 CBY42363.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AFG1_ATPase PF03969.16 CBY42363.1 - 0.11 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase AAA_18 PF13238.6 CBY42363.1 - 0.14 12.7 0.1 0.61 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBY42363.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 CBY42363.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin UCR_Fe-S_N PF10399.9 CBY42363.1 - 1.9 7.9 3.8 0.47 9.8 0.7 1.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Carn_acyltransf PF00755.20 CBY42365.1 - 4.1e-21 75.2 0.0 4.5e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Nuc_sug_transp PF04142.15 CBY42366.1 - 3.4e-22 79.0 24.7 8.5e-22 77.7 24.7 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBY42366.1 - 0.00061 20.0 25.5 0.0046 17.1 2.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CBY42366.1 - 0.36 10.0 23.5 0.36 10.0 8.6 2.2 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport RabGAP-TBC PF00566.18 CBY42368.1 - 1.7e-06 27.9 0.4 0.00046 19.9 0.8 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 CBY42368.1 - 2.5e-05 24.8 0.0 5.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Pribosyl_synth PF14572.6 CBY42369.1 - 2.8e-33 115.5 1.7 3e-29 102.4 1.2 2.0 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBY42369.1 - 1.5e-13 50.6 0.7 2.2e-13 50.0 0.5 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GTP-bdg_N PF13167.6 CBY42369.1 - 0.045 14.4 0.5 2 9.2 0.4 2.6 1 1 1 2 2 2 0 GTP-binding GTPase N-terminal Glycos_transf_2 PF00535.26 CBY42370.1 - 1.4e-31 109.6 0.0 1.5e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY42370.1 - 6.4e-13 49.1 0.0 7.6e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CBY42370.1 - 1e-08 35.0 0.0 1.1e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CBY42370.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 DAGK_acc PF00609.19 CBY42371.1 - 2.3e-41 141.8 0.0 4.9e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain SAM_2 PF07647.17 CBY42371.1 - 9.9e-05 22.4 0.1 0.00023 21.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LrgB PF04172.16 CBY42372.1 - 0.45 10.0 6.4 6.8 6.2 1.7 2.6 2 0 0 2 2 2 0 LrgB-like family Kelch_6 PF13964.6 CBY42373.1 - 0.13 12.6 1.6 5.6 7.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif WD40_like PF17005.5 CBY42377.1 - 0.00025 20.5 0.1 0.00046 19.6 0.1 1.5 1 0 0 1 1 1 1 WD40-like domain PALB2_WD40 PF16756.5 CBY42377.1 - 0.017 14.0 0.1 1.5 7.6 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Thioredoxin PF00085.20 CBY42378.1 - 1.7e-09 37.6 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CBY42378.1 - 0.001 18.1 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Phosducin UCH PF00443.29 CBY42379.1 - 4.1e-35 121.5 6.5 4.1e-35 121.5 6.5 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY42379.1 - 3.7e-08 33.3 21.1 8.2e-07 28.9 21.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Coat_F PF07875.12 CBY42379.1 - 0.07 13.4 0.0 0.39 11.0 0.0 2.4 1 0 0 1 1 1 0 Coat F domain NOB1_Zn_bind PF08772.11 CBY42379.1 - 0.18 12.0 1.8 0.51 10.5 1.8 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like CH PF00307.31 CBY42380.1 - 6.5e-37 126.1 0.1 3.6e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CBY42380.1 - 0.00018 21.3 0.0 0.0012 18.6 0.0 2.2 3 0 0 3 3 3 1 CAMSAP CH domain Aconitase PF00330.20 CBY42381.1 - 1.3e-127 426.6 0.0 1.6e-127 426.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Acetyltransf_1 PF00583.25 CBY42383.1 - 7.1e-14 52.0 0.1 8.5e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBY42383.1 - 5.9e-11 42.4 0.2 7.7e-11 42.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBY42383.1 - 1.3e-09 38.4 0.1 2e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY42383.1 - 0.00014 22.1 0.1 0.00017 21.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBY42383.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 CBY42383.1 - 0.041 14.0 0.1 0.098 12.8 0.1 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Host_attach PF10116.9 CBY42384.1 - 0.018 15.7 2.2 0.022 15.3 0.2 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells Fibrinogen_C PF00147.18 CBY42385.1 - 6.5e-31 107.8 10.0 1.5e-20 74.0 7.1 3.0 2 1 0 2 2 2 2 Fibrinogen beta and gamma chains, C-terminal globular domain AP_endonuc_2 PF01261.24 CBY42385.1 - 0.033 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Zip PF02535.22 CBY42386.1 - 0.0093 15.2 0.8 0.011 15.0 0.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Presenilin PF01080.17 CBY42386.1 - 0.014 14.2 7.7 0.016 14.0 7.7 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CBY42386.1 - 0.017 15.2 0.8 0.019 15.0 0.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endomucin PF07010.12 CBY42386.1 - 0.053 13.5 21.8 0.059 13.3 21.8 1.1 1 0 0 1 1 1 0 Endomucin Raftlin PF15250.6 CBY42386.1 - 0.094 11.5 7.1 0.11 11.3 7.1 1.0 1 0 0 1 1 1 0 Raftlin ABC2_membrane_3 PF12698.7 CBY42386.1 - 0.13 11.3 8.4 0.17 11.0 8.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MDFI PF15316.6 CBY42386.1 - 0.15 12.2 6.8 0.19 11.8 6.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor MCLC PF05934.11 CBY42386.1 - 0.39 9.4 13.0 0.48 9.1 13.0 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RIFIN PF02009.16 CBY42386.1 - 0.6 9.9 9.5 0.67 9.8 9.5 1.2 1 0 0 1 1 1 0 Rifin Suf PF05843.14 CBY42386.1 - 0.61 10.0 10.2 0.67 9.9 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CBY42386.1 - 0.79 9.7 17.0 0.93 9.4 17.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pannexin_like PF12534.8 CBY42386.1 - 1.4 7.9 10.9 1.8 7.6 10.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Ndc1_Nup PF09531.10 CBY42386.1 - 1.4 7.5 12.4 1.7 7.2 12.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.13 CBY42386.1 - 1.5 7.8 13.3 1.9 7.4 13.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4400 PF14348.6 CBY42386.1 - 2.9 7.4 6.5 4 6.9 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Plasmodium_Vir PF05795.11 CBY42386.1 - 3.3 7.0 7.4 4.5 6.6 7.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.13 CBY42386.1 - 3.6 7.1 14.0 4.3 6.9 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.9 CBY42386.1 - 7.4 5.7 20.6 8.5 5.5 20.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 CBY42386.1 - 7.6 6.5 40.1 1.6e+02 2.2 40.1 2.1 1 1 0 1 1 1 0 Mucin-like glycoprotein CP2 PF04516.15 CBY42391.1 - 1.8e-62 210.7 0.6 2.6e-62 210.1 0.6 1.2 1 0 0 1 1 1 1 CP2 transcription factor Dpy19 PF10034.9 CBY42392.1 - 2.1e-41 141.9 0.1 2.3e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation KNOX1 PF03790.13 CBY42392.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 KNOX1 domain Phospholip_A2_1 PF00068.19 CBY42393.1 - 4.4e-07 30.4 1.9 4.4e-07 30.4 1.9 2.0 2 0 0 2 2 2 1 Phospholipase A2 Guanylate_cyc PF00211.20 CBY42395.1 - 1.1e-08 35.0 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Mit_KHE1 PF10173.9 CBY42396.1 - 0.079 13.0 1.3 0.085 12.9 1.3 1.0 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Lipocalin_7 PF14651.6 CBY42397.1 - 6.5e-16 58.4 0.5 7.7e-16 58.2 0.5 1.0 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family PK_C PF02887.16 CBY42397.1 - 0.0043 17.3 1.0 0.0046 17.2 0.3 1.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HORMA PF02301.18 CBY42398.1 - 3e-13 49.8 0.2 3.7e-13 49.6 0.2 1.1 1 0 0 1 1 1 1 HORMA domain GPS2_interact PF15784.5 CBY42399.1 - 0.02 15.3 11.5 0.02 15.3 11.5 3.3 2 1 1 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF2090 PF09863.9 CBY42399.1 - 0.021 13.9 2.7 0.036 13.1 2.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) FAM167 PF11652.8 CBY42399.1 - 5.9 7.4 9.3 0.76 10.3 2.2 2.5 2 0 0 2 2 2 0 FAM167 eIF3g PF12353.8 CBY42401.1 - 0.0024 18.3 0.7 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G Hamartin PF04388.12 CBY42401.1 - 0.23 10.1 12.8 0.35 9.5 12.8 1.2 1 0 0 1 1 1 0 Hamartin protein Peptidase_M29 PF02073.15 CBY42402.1 - 0.032 13.0 0.6 3.1 6.5 0.4 2.1 2 0 0 2 2 2 0 Thermophilic metalloprotease (M29) WD40 PF00400.32 CBY42403.1 - 1.2e-20 73.4 17.6 0.00084 20.1 0.2 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY42403.1 - 3.2e-06 27.4 1.2 1.6 9.1 0.0 5.3 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain nos_propeller PF18764.1 CBY42403.1 - 0.012 15.5 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat DUF1513 PF07433.11 CBY42403.1 - 0.15 11.1 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) RhoGEF PF00621.20 CBY42404.1 - 1.1e-26 94.2 0.1 1.7e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 CBY42404.1 - 0.00042 20.6 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain McrBC PF10117.9 CBY42404.1 - 0.0037 16.5 0.2 0.0064 15.7 0.2 1.3 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component PH PF00169.29 CBY42404.1 - 0.056 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 PH domain UQ_con PF00179.26 CBY42405.1 - 3.1e-45 153.3 0.0 3.8e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY42405.1 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBY42405.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CBY42405.1 - 0.03 14.6 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Dpy19 PF10034.9 CBY42408.1 - 2.2e-165 551.6 11.7 2.5e-165 551.4 11.7 1.0 1 0 0 1 1 1 1 Q-cell neuroblast polarisation Collagen PF01391.18 CBY42411.1 - 1.3e-08 34.5 31.8 1e-07 31.6 31.8 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) VWA PF00092.28 CBY42411.1 - 4.3e-08 33.6 0.6 5.6e-08 33.2 0.6 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CBY42411.1 - 0.034 14.8 0.1 0.053 14.2 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF325 PF03804.13 CBY42411.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Viral proteins of unknown function PDZ PF00595.24 CBY42413.1 - 8.9e-09 35.6 0.8 5.1e-08 33.2 0.3 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBY42413.1 - 4.5e-07 29.6 0.1 2e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CBY42413.1 - 0.001 19.3 0.2 0.0023 18.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain TraI_2B PF18340.1 CBY42413.1 - 0.0023 18.0 0.0 0.0069 16.4 0.0 1.8 1 0 0 1 1 1 1 DNA relaxase TraI 2B/2B-like domain Pns11_12 PF17464.2 CBY42413.1 - 0.069 12.9 28.3 0.052 13.3 13.2 2.6 3 0 0 3 3 3 0 Non-structural protein 11 and 12 C2 PF00168.30 CBY42414.1 - 3.5e-10 40.1 0.0 3.8e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 C2 domain Lipase PF00151.19 CBY42416.1 - 1.4e-20 73.9 0.0 1.7e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Lipase Lipase_3 PF01764.25 CBY42416.1 - 0.0028 17.5 0.0 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CBY42416.1 - 0.0089 15.6 0.0 0.0094 15.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 CBY42416.1 - 0.057 12.3 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Sushi PF00084.20 CBY42417.1 - 6.8e-31 106.6 7.3 1.2e-07 32.2 0.1 4.6 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) HRM PF02793.22 CBY42417.1 - 6e-08 32.9 12.5 0.0032 17.7 0.2 4.6 4 0 0 4 4 4 4 Hormone receptor domain Lectin_C PF00059.21 CBY42417.1 - 0.00018 22.2 0.6 0.00018 22.2 0.6 1.8 2 0 0 2 2 2 1 Lectin C-type domain Thioredoxin PF00085.20 CBY42418.1 - 1.9e-18 66.4 0.7 5.2e-15 55.3 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CBY42418.1 - 5.2e-09 36.3 10.5 2.2e-05 24.4 5.6 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBY42418.1 - 3.5e-05 24.2 5.0 0.0087 16.5 0.1 3.9 4 1 1 5 5 5 2 Thioredoxin-like domain TraF PF13728.6 CBY42418.1 - 0.00037 20.4 0.1 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CBY42418.1 - 0.0066 16.8 4.1 0.088 13.2 0.0 3.5 2 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CBY42418.1 - 0.027 14.6 0.8 0.75 10.0 0.0 3.1 2 1 0 3 3 3 0 Thioredoxin-like Turandot PF07240.11 CBY42418.1 - 0.063 13.2 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Pkinase PF00069.25 CBY42419.1 - 2.2e-23 82.9 0.0 2.4e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42419.1 - 5.1e-15 55.5 0.0 5.3e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY42419.1 - 0.028 13.8 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBY42419.1 - 0.063 12.0 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CBY42419.1 - 0.077 12.0 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C3HC4 PF00097.25 CBY42421.1 - 2.9e-05 23.8 7.7 5.7e-05 22.9 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY42421.1 - 3.6e-05 23.5 14.2 5.4e-05 23.0 14.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 CBY42421.1 - 4.9e-05 23.7 4.0 6.5e-05 23.3 4.0 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_4 PF14570.6 CBY42421.1 - 0.00043 20.0 9.9 0.00083 19.1 9.9 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 CBY42421.1 - 0.00084 19.6 10.8 0.0016 18.7 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY42421.1 - 0.11 12.4 11.5 0.36 10.7 11.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY42421.1 - 0.18 11.8 12.4 0.4 10.7 12.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain FA_desaturase PF00487.24 CBY42422.1 - 1.6e-11 44.6 7.0 3.3e-11 43.5 7.0 1.6 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBY42422.1 - 7.7e-11 42.0 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 CBY42423.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42423.1 - 7e-08 32.1 0.3 1.3e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase UPF0180 PF03698.13 CBY42427.1 - 0.0024 18.0 0.4 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0180) DUF5591 PF17884.1 CBY42427.1 - 0.095 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Plectin PF00681.20 CBY42429.1 - 4.4e-33 112.9 0.7 2.8e-05 23.9 0.1 8.3 7 2 2 9 9 9 7 Plectin repeat Homeodomain PF00046.29 CBY42430.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY42430.1 - 0.0015 18.4 0.2 0.011 15.7 0.0 2.4 3 0 0 3 3 3 1 Homeobox KN domain DUF5578 PF17741.1 CBY42432.1 - 3.3e-38 131.6 0.2 3.8e-38 131.4 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5578) Xan_ur_permease PF00860.20 CBY42434.1 - 1.5e-55 188.5 4.1 1.5e-55 188.5 4.1 1.6 2 0 0 2 2 2 1 Permease family Collagen PF01391.18 CBY42435.1 - 1.3e-74 245.9 280.7 6.5e-09 35.4 24.4 10.5 1 1 7 8 8 8 7 Collagen triple helix repeat (20 copies) C4 PF01413.19 CBY42435.1 - 3e-32 111.3 0.6 1e-20 74.1 0.1 2.2 2 0 0 2 2 2 2 C-terminal tandem repeated domain in type 4 procollagen N6_N4_Mtase PF01555.18 CBY42436.1 - 0.064 12.9 0.4 0.11 12.1 0.2 1.5 2 0 0 2 2 2 0 DNA methylase Peptidase_M1 PF01433.20 CBY42437.1 - 8.8e-52 175.8 0.2 1.6e-51 175.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBY42437.1 - 4.4e-39 134.6 1.0 8.1e-39 133.7 1.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBY42437.1 - 1.6e-08 34.5 0.2 4.1e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Flavi_glycop_C PF02832.16 CBY42437.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Homeodomain PF00046.29 CBY42438.1 - 1.6e-22 79.1 4.7 2.8e-22 78.3 4.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY42438.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain PAN_1 PF00024.26 CBY42439.1 - 0.0033 17.4 5.6 0.0056 16.6 5.6 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 CBY42439.1 - 0.032 14.0 7.4 0.026 14.3 6.2 1.6 1 1 0 1 1 1 0 PAN-like domain DUF1374 PF07118.11 CBY42439.1 - 0.12 12.9 0.1 0.19 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) Herpes_capsid PF06112.11 CBY42440.1 - 0.0074 16.4 4.4 0.0093 16.0 4.4 1.3 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Myc_N PF01056.18 CBY42440.1 - 0.032 14.1 0.7 0.04 13.8 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Glyco_trans_1_2 PF13524.6 CBY42440.1 - 0.046 14.1 0.2 7.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sec3_C PF09763.9 CBY42440.1 - 0.047 12.1 0.2 0.061 11.7 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 PCM1_C PF15717.5 CBY42440.1 - 0.26 9.9 4.9 0.33 9.6 4.9 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus SR-25 PF10500.9 CBY42440.1 - 5.9 6.4 9.4 7.3 6.1 9.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein rve PF00665.26 CBY42446.1 - 3.5e-06 27.2 0.0 4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L21e PF01157.18 CBY42447.1 - 0.03 14.2 0.1 0.047 13.5 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein L21e Y_phosphatase PF00102.27 CBY42449.1 - 4.7e-15 55.8 0.0 5.6e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HECT PF00632.25 CBY42450.1 - 3.4e-65 220.5 0.0 3.8e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_aberr PF17017.5 CBY42451.1 - 0.35 11.0 6.5 4.6 7.3 6.5 2.1 1 1 0 1 1 1 0 Aberrant zinc-finger Mucin PF01456.17 CBY42451.1 - 6.5 6.7 14.5 15 5.6 14.5 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein Pro_isomerase PF00160.21 CBY42453.1 - 3.8e-42 144.2 0.0 5.7e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD P63C PF10546.9 CBY42453.1 - 0.23 12.0 1.5 28 5.4 0.7 2.4 1 1 1 2 2 2 0 P63C domain Meiosis_expr PF15163.6 CBY42456.1 - 1.5e-32 112.0 4.0 1.9e-32 111.8 4.0 1.1 1 0 0 1 1 1 1 Meiosis-expressed Cir_N PF10197.9 CBY42457.1 - 5.6e-06 26.4 7.0 5.6e-06 26.4 7.0 4.7 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PUD1_2 PF18457.1 CBY42459.1 - 0.021 14.8 0.2 0.038 14.0 0.2 1.4 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 SspH PF08141.12 CBY42459.1 - 5.6 7.2 10.4 20 5.4 0.2 3.8 3 1 0 3 3 3 0 Small acid-soluble spore protein H family DUF2096 PF09869.9 CBY42460.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) SLAC1 PF03595.17 CBY42463.1 - 0.12 11.6 0.5 0.13 11.5 0.5 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel zf-C2H2_4 PF13894.6 CBY42465.1 - 2.2e-07 31.1 26.0 0.026 15.4 0.1 5.9 6 0 0 6 6 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CBY42465.1 - 0.00019 21.7 28.2 0.019 15.4 0.2 6.4 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf_UBZ PF18439.1 CBY42465.1 - 0.011 15.3 7.0 0.39 10.4 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 CBY42465.1 - 0.012 16.0 0.1 0.012 16.0 0.1 6.0 7 1 0 7 7 7 0 Zinc-finger double domain DUF1059 PF06348.11 CBY42465.1 - 0.018 15.3 0.1 0.018 15.3 0.1 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1059) DUF1610 PF07754.11 CBY42465.1 - 0.047 13.7 1.0 0.16 12.0 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-H2C2_5 PF13909.6 CBY42465.1 - 0.06 13.1 0.1 0.06 13.1 0.1 2.8 4 0 0 4 4 3 0 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 CBY42465.1 - 0.17 11.5 9.0 0.46 10.1 0.3 3.7 3 1 1 4 4 4 0 Zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CBY42465.1 - 0.79 9.9 7.4 28 4.9 0.3 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 CBY42465.1 - 0.98 9.5 6.2 21 5.3 0.0 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-Di19 PF05605.12 CBY42465.1 - 1.6 9.1 17.3 0.35 11.2 3.7 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 CBY42465.1 - 3.2 7.3 6.4 5.7 6.5 0.2 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2HE PF16278.5 CBY42465.1 - 5.7 7.5 12.0 16 6.1 0.0 3.9 3 2 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CBY42465.1 - 9.3 6.4 21.5 4.7 7.3 0.3 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Pkinase PF00069.25 CBY42467.1 - 3.3e-11 43.1 0.0 5.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42467.1 - 3.7e-09 36.3 0.0 5.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU PF00009.27 CBY42470.1 - 1.5e-27 96.4 0.1 4.3e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBY42470.1 - 7.1e-17 61.5 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 CBY42470.1 - 7.3e-16 57.8 1.6 9.1e-16 57.5 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CBY42470.1 - 7.6e-06 26.2 1.0 0.098 13.1 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBY42470.1 - 0.0015 18.6 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Transposase_mut PF00872.18 CBY42470.1 - 0.039 12.8 0.0 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase, Mutator family Ras PF00071.22 CBY42470.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras family ATP-gua_Ptrans PF00217.19 CBY42471.1 - 4.9e-25 88.3 0.0 6.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 CBY42471.1 - 4.5e-24 84.6 0.1 1.5e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain DUF1198 PF06711.11 CBY42471.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) MtaB PF12176.8 CBY42472.1 - 0.097 11.4 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit WD40 PF00400.32 CBY42473.1 - 7.6e-08 32.9 1.3 0.0053 17.6 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY42473.1 - 0.0099 16.2 0.2 1.1 9.6 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY42473.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain Pkinase PF00069.25 CBY42475.1 - 1.3e-10 41.1 0.3 2.1e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42475.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CUT PF02376.15 CBY42476.1 - 3e-31 107.4 0.1 5.2e-31 106.6 0.1 1.4 1 0 0 1 1 1 1 CUT domain Homeodomain PF00046.29 CBY42476.1 - 9.4e-12 44.6 1.1 2e-11 43.6 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CBY42476.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Myf5 PF12232.8 CBY42476.1 - 0.012 16.3 4.0 0.031 15.1 3.6 1.9 2 0 0 2 2 2 0 Myogenic determination factor 5 TFIIS_M PF07500.14 CBY42477.1 - 5.4e-05 23.6 0.1 6.2e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain MCM PF00493.23 CBY42478.1 - 2.6e-95 317.8 0.0 3.4e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY42478.1 - 5.9e-26 90.8 0.2 9.5e-26 90.1 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CBY42478.1 - 2.3e-09 36.9 0.1 3.1e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBY42478.1 - 2.5e-08 34.0 0.0 6.6e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBY42478.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CBY42478.1 - 0.029 14.8 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBY42478.1 - 0.054 13.2 0.3 0.54 10.0 0.0 2.4 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBY42478.1 - 0.07 12.8 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CBY42478.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CBY42478.1 - 0.13 12.6 0.1 0.57 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain SelB-wing_1 PF09105.10 CBY42479.1 - 0.035 14.1 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Acetyltransf_3 PF13302.7 CBY42480.1 - 3.1e-25 89.5 0.8 4.4e-25 89.0 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBY42480.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY42480.1 - 0.0015 18.7 0.4 0.005 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CBY42480.1 - 0.0031 17.7 0.2 0.0055 16.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L37ae PF01780.19 CBY42481.1 - 1.4e-36 124.5 4.6 1.5e-36 124.3 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Ribosomal_S24e PF01282.19 CBY42482.1 - 6.9e-29 99.6 0.0 9.2e-29 99.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S24e Tetraspanin PF00335.20 CBY42483.1 - 0.016 15.0 7.4 0.017 14.8 7.4 1.1 1 0 0 1 1 1 0 Tetraspanin family GPI2 PF06432.11 CBY42483.1 - 0.048 13.1 4.4 0.066 12.6 4.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase TMEM215 PF15746.5 CBY42483.1 - 0.19 11.2 1.4 0.24 10.8 1.4 1.1 1 0 0 1 1 1 0 TMEM215 family Phage_holin_3_6 PF07332.11 CBY42483.1 - 1 9.4 6.9 1.2 9.2 6.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5305 PF17231.2 CBY42483.1 - 4.1 6.8 7.0 0.53 9.7 0.3 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 CBY42483.1 - 4.1 6.1 10.9 4.4 6.0 10.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4083 PF13314.6 CBY42483.1 - 9.1 6.3 14.7 0.42 10.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Glycos_transf_2 PF00535.26 CBY42484.1 - 5.3e-13 49.1 0.0 1.3e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBY42484.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Brix PF04427.18 CBY42484.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Brix domain Strabismus PF06638.11 CBY42486.1 - 1.6e-202 673.7 0.7 1.9e-202 673.4 0.7 1.0 1 0 0 1 1 1 1 Strabismus protein BofC_C PF08955.10 CBY42488.1 - 0.037 14.1 0.2 0.1 12.7 0.2 1.7 1 1 0 1 1 1 0 BofC C-terminal domain Arf PF00025.21 CBY42490.1 - 8.3e-56 188.2 0.0 1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBY42490.1 - 5.3e-14 52.1 0.0 6.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY42490.1 - 1.9e-13 50.7 0.0 3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBY42490.1 - 2.5e-12 46.6 0.0 3.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBY42490.1 - 5.7e-10 38.9 0.1 1.3e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBY42490.1 - 1.5e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY42490.1 - 0.013 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 CBY42490.1 - 0.059 12.4 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein 6PF2K PF01591.18 CBY42490.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2754 PF10953.8 CBY42490.1 - 0.11 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Pkinase PF00069.25 CBY42491.1 - 0.0027 17.1 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42491.1 - 0.025 13.9 0.0 0.77 9.0 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase zf-C2H2 PF00096.26 CBY42493.1 - 7.5e-07 29.3 13.9 0.015 15.7 0.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY42493.1 - 0.0002 21.9 11.6 0.32 11.9 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBY42493.1 - 0.025 14.9 8.4 1.7 9.0 4.6 3.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CBY42493.1 - 0.045 13.4 7.6 0.097 12.3 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-P11 PF03854.14 CBY42493.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf_C2H2_ZHX PF18387.1 CBY42493.1 - 0.38 10.4 3.9 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CBY42493.1 - 0.61 10.6 5.5 28 5.3 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CBY42493.1 - 2 8.4 6.8 12 5.8 0.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 CBY42493.1 - 4 6.5 9.8 2.8 7.1 1.1 2.8 1 1 1 2 2 2 0 Putative actin-like family Phospholip_A2_1 PF00068.19 CBY42495.1 - 0.0028 18.1 0.7 0.0028 18.1 0.7 2.0 2 0 0 2 2 2 1 Phospholipase A2 PHD PF00628.29 CBY42496.1 - 1.9e-08 34.1 12.7 3.3e-08 33.3 12.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CBY42496.1 - 5.3e-05 22.7 6.9 0.00012 21.6 6.9 1.6 1 1 0 1 1 1 1 PHD-finger RAG2_PHD PF13341.6 CBY42496.1 - 0.0039 17.2 0.6 0.0067 16.5 0.6 1.3 1 0 0 1 1 1 1 RAG2 PHD domain DNA_pol3_a_NII PF11490.8 CBY42496.1 - 0.0091 15.9 0.6 0.0091 15.9 0.6 2.0 3 0 0 3 3 3 1 DNA polymerase III polC-type N-terminus II BUD22 PF09073.10 CBY42496.1 - 0.069 12.5 25.0 0.11 11.9 25.0 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CBY42496.1 - 1.4 6.9 18.3 2 6.4 18.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 CBY42496.1 - 2.5 7.8 27.8 4.6 6.9 27.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 CBY42496.1 - 3.4 6.4 10.4 4.4 6.0 10.4 1.2 1 0 0 1 1 1 0 Presenilin ZapB PF06005.12 CBY42497.1 - 0.0094 16.4 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Cell division protein ZapB APC_N_CC PF16689.5 CBY42497.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain HALZ PF02183.18 CBY42497.1 - 0.016 15.4 0.5 0.028 14.6 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 CBY42497.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator YscO PF07321.12 CBY42497.1 - 0.052 13.5 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO CCDC144C PF14915.6 CBY42497.1 - 0.054 12.6 0.0 0.056 12.6 0.0 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region LPP PF04728.13 CBY42497.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper zf-C2H2 PF00096.26 CBY42500.1 - 6.4e-07 29.5 25.7 0.0054 17.1 0.4 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY42500.1 - 6.5e-07 29.5 31.7 0.0022 18.4 3.2 4.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY42500.1 - 3.1e-06 27.6 31.6 0.067 14.1 2.4 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CBY42500.1 - 0.0063 16.4 0.6 0.0063 16.4 0.6 4.8 4 2 0 4 4 4 1 zinc-finger of a C2HC-type zf-DNA_Pol PF08996.10 CBY42500.1 - 0.021 14.6 17.2 0.095 12.4 6.3 2.5 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-met PF12874.7 CBY42500.1 - 0.028 14.8 18.7 0.1 13.0 0.5 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PHD_Oberon PF07227.11 CBY42500.1 - 0.04 13.8 15.0 0.83 9.5 4.2 2.5 1 1 1 2 2 2 0 PHD - plant homeodomain finger protein zf_UBZ PF18439.1 CBY42500.1 - 0.051 13.2 13.3 7.5 6.2 0.4 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_4 PF13717.6 CBY42500.1 - 0.094 12.7 16.9 1 9.3 6.8 3.9 2 1 1 3 3 3 0 zinc-ribbon domain HypA PF01155.19 CBY42500.1 - 0.21 11.6 15.6 1.6 8.8 6.2 2.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUP PF00674.18 CBY42500.1 - 0.23 11.6 7.4 4.7 7.4 1.3 2.4 2 0 0 2 2 2 0 DUP family zinc_ribbon_5 PF13719.6 CBY42500.1 - 1.1 9.1 24.7 0.44 10.3 9.7 3.6 3 0 0 3 3 3 0 zinc-ribbon domain XPA_N PF01286.18 CBY42500.1 - 1.2 9.3 20.9 0.71 10.0 0.6 4.6 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 CBY42500.1 - 2.9 7.7 12.6 1.3 8.9 1.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CBY42500.1 - 4 7.6 23.0 1 9.5 4.6 4.6 4 1 1 5 5 5 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 CBY42500.1 - 4.1 7.8 20.6 0.13 12.5 3.2 3.2 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CBY42500.1 - 4.3 7.7 22.6 22 5.5 13.2 3.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-ribbon_3 PF13248.6 CBY42500.1 - 4.9 6.7 10.5 4.6 6.8 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain LIM PF00412.22 CBY42500.1 - 8.3 6.7 26.8 0.76 10.0 10.6 3.3 1 1 1 2 2 1 0 LIM domain PBD PF00786.28 CBY42502.1 - 5.9e-08 33.0 0.1 9.8e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain Exo84_C PF16528.5 CBY42502.1 - 0.055 13.3 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Exocyst component 84 C-terminal FGGY_N PF00370.21 CBY42502.1 - 0.091 12.3 0.1 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain COPI_C PF06957.11 CBY42504.1 - 1.5e-64 218.2 0.2 1.7e-64 218.1 0.2 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus TrwB_AAD_bind PF10412.9 CBY42504.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Acyl_transf_3 PF01757.22 CBY42505.1 - 0.011 14.8 2.2 0.012 14.8 0.1 1.8 2 0 0 2 2 2 0 Acyltransferase family Fib_alpha PF08702.10 CBY42506.1 - 2.6e-05 24.4 0.6 3.3e-05 24.1 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CBY42506.1 - 0.00054 20.5 1.8 0.00063 20.2 1.8 1.1 1 0 0 1 1 1 1 Fez1 TMF_DNA_bd PF12329.8 CBY42506.1 - 0.002 18.1 3.6 0.015 15.3 3.4 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 CBY42506.1 - 0.0025 17.9 1.4 0.0068 16.5 1.4 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 CENP-F_leu_zip PF10473.9 CBY42506.1 - 0.0025 17.8 3.6 0.0034 17.4 3.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CBY42506.1 - 0.0031 17.8 1.9 0.0033 17.7 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CBY42506.1 - 0.0053 15.7 1.2 0.0058 15.6 1.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Shugoshin_N PF07558.11 CBY42506.1 - 0.006 16.4 0.1 0.029 14.2 0.0 2.1 1 1 1 2 2 2 1 Shugoshin N-terminal coiled-coil region CEP209_CC5 PF16574.5 CBY42506.1 - 0.0089 16.2 0.8 0.011 15.9 0.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 ERM PF00769.19 CBY42506.1 - 0.0091 15.8 0.7 0.01 15.7 0.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Phage_GP20 PF06810.11 CBY42506.1 - 0.019 14.8 0.6 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Anti-adapt_IraP PF10796.9 CBY42506.1 - 0.02 15.5 0.2 0.032 14.8 0.2 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF1664 PF07889.12 CBY42506.1 - 0.02 14.9 0.6 0.025 14.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CBY42506.1 - 0.021 15.5 1.5 0.19 12.4 0.9 2.1 1 1 1 2 2 2 0 SlyX Tropomyosin_1 PF12718.7 CBY42506.1 - 0.038 14.1 2.8 0.047 13.8 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like Csm1_N PF18504.1 CBY42506.1 - 0.057 13.8 3.1 0.39 11.1 2.3 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain NPV_P10 PF05531.12 CBY42506.1 - 0.062 13.8 0.4 0.15 12.6 0.4 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 CBY42506.1 - 0.11 12.9 2.2 0.68 10.3 1.5 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CUB PF00431.20 CBY42507.1 - 3e-14 53.3 3.7 1.2e-11 45.0 1.9 2.5 2 0 0 2 2 2 2 CUB domain SR-25 PF10500.9 CBY42507.1 - 0.22 11.1 5.5 0.37 10.4 5.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RHD_dimer PF16179.5 CBY42509.1 - 2.5e-19 69.2 0.2 4.7e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain RHD_DNA_bind PF00554.22 CBY42509.1 - 6e-11 42.6 1.4 1.7e-09 37.8 1.4 2.4 1 1 0 1 1 1 1 Rel homology DNA-binding domain TIG PF01833.24 CBY42509.1 - 7.6e-06 25.9 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 IPT/TIG domain Trypsin PF00089.26 CBY42511.1 - 9.9e-08 32.1 0.0 9.9e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Trypsin UPAR_LY6_2 PF16975.5 CBY42511.1 - 0.0059 16.8 12.4 0.0096 16.1 12.4 1.3 1 0 0 1 1 1 1 Ly6/PLAUR domain-containing protein 6, Lypd6 DUF1986 PF09342.11 CBY42511.1 - 0.097 13.1 0.5 0.2 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) zf-Tim10_DDP PF02953.15 CBY42512.1 - 2.1e-10 40.1 1.9 3.9e-10 39.2 1.9 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_6 PF12697.7 CBY42513.1 - 0.019 15.6 0.0 0.019 15.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_7 PF12775.7 CBY42515.1 - 6.8e-81 270.1 0.3 3e-80 268.0 0.1 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_6 PF12774.7 CBY42515.1 - 6.1e-28 97.7 0.0 3.5e-26 92.0 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 CBY42515.1 - 7.3e-26 90.8 0.0 2e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBY42515.1 - 2.9e-17 62.7 0.1 1e-16 60.9 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_8 PF12780.7 CBY42515.1 - 6e-17 61.8 0.5 3.5e-16 59.3 0.6 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 CBY42515.1 - 5.5e-13 49.1 0.0 3.7e-05 23.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 CBY42515.1 - 0.0016 18.9 0.0 0.46 10.9 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CBY42515.1 - 0.0041 16.5 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 CBY42515.1 - 0.0058 16.6 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea EF-hand_6 PF13405.6 CBY42515.1 - 0.0074 16.1 1.1 0.029 14.3 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain AAA_22 PF13401.6 CBY42515.1 - 0.0084 16.4 0.0 0.16 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CBY42515.1 - 0.012 14.7 0.0 0.11 11.6 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_14 PF13173.6 CBY42515.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBY42515.1 - 0.039 14.3 0.1 1.8 9.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 CBY42515.1 - 0.047 13.4 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 CBY42515.1 - 0.048 12.6 0.0 0.17 10.8 0.0 1.9 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 CBY42515.1 - 0.084 13.1 0.3 2.7 8.3 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 CBY42515.1 - 0.095 12.3 0.4 0.44 10.2 0.1 2.4 2 0 0 2 2 1 0 EF hand FtsK_SpoIIIE PF01580.18 CBY42515.1 - 0.11 11.9 0.1 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family EF-hand_7 PF13499.6 CBY42515.1 - 0.12 12.8 0.8 0.65 10.5 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain pair RsgA_GTPase PF03193.16 CBY42515.1 - 0.18 11.7 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activat PF00158.26 CBY42515.1 - 0.2 11.4 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBY42515.1 - 0.3 10.9 1.0 6.1 6.7 0.0 3.2 4 0 0 4 4 3 0 P-loop containing region of AAA domain Trypan_PARP PF05887.11 CBY42516.1 - 1.9 8.5 14.0 2.6 8.0 14.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 CBY42517.1 - 2.4 8.1 10.0 3.6 7.5 10.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amidase PF01425.21 CBY42518.1 - 2.7e-76 257.4 0.0 9.5e-76 255.6 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF4032 PF13224.6 CBY42520.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) EF-hand_1 PF00036.32 CBY42522.1 - 8.6e-15 53.1 4.2 5.3e-05 22.5 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CBY42522.1 - 1.1e-14 54.7 6.0 1.6e-14 54.1 0.5 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY42522.1 - 1.8e-10 39.8 8.0 0.00016 21.4 0.1 4.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBY42522.1 - 5.1e-08 32.6 2.4 0.0022 17.8 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY42522.1 - 5.1e-07 28.9 5.3 0.00028 20.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 CBY42522.1 - 0.21 11.5 3.2 6.1 6.8 0.1 3.8 3 1 1 4 4 4 0 EF hand Cytochrom_C552 PF02335.15 CBY42524.1 - 0.15 11.0 5.0 0.18 10.7 5.0 1.1 1 0 0 1 1 1 0 Cytochrome c552 DUF3037 PF11236.8 CBY42524.1 - 0.31 11.5 2.0 4.8 7.6 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) MtaB PF12176.8 CBY42524.1 - 0.33 9.7 3.9 0.52 9.0 3.9 1.3 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit SOAR PF16533.5 CBY42524.1 - 0.66 10.0 14.5 2.3 8.2 6.3 2.8 1 1 2 3 3 3 0 STIM1 Orai1-activating region Phage_HK97_TLTM PF06120.11 CBY42524.1 - 4.2 6.5 15.6 5.4 6.1 15.6 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Sulfatase PF00884.23 CBY42525.1 - 1.1e-12 47.9 0.1 1.3e-12 47.8 0.1 1.0 1 0 0 1 1 1 1 Sulfatase T7SS_ESX1_EccB PF05108.13 CBY42526.1 - 0.047 12.4 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B WD40 PF00400.32 CBY42527.1 - 8.7e-16 58.0 3.8 2.6e-08 34.4 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY42527.1 - 5.4e-10 39.4 0.1 0.084 13.2 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY42527.1 - 0.0058 16.0 0.4 0.78 9.0 0.1 2.3 1 1 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 CBY42527.1 - 0.016 15.2 0.1 1.8 8.6 0.1 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 CBY42528.1 - 0.00084 19.6 0.1 0.048 13.9 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain OST-HTH PF12872.7 CBY42529.1 - 0.074 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 OST-HTH/LOTUS domain DUF3808 PF10300.9 CBY42531.1 - 4.1e-25 88.5 0.0 5.8e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CaMBD PF02888.16 CBY42534.1 - 3.8e-37 126.3 8.3 7.5e-37 125.4 8.3 1.5 1 0 0 1 1 1 1 Calmodulin binding domain Ion_trans_2 PF07885.16 CBY42534.1 - 2.2e-14 53.2 3.1 5.3e-14 52.0 3.1 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY42534.1 - 2.3e-05 23.8 2.9 3.3e-05 23.2 2.9 1.3 1 0 0 1 1 1 1 Ion transport protein IRK PF01007.20 CBY42534.1 - 0.0094 15.8 3.4 0.0094 15.8 3.4 2.3 2 1 2 4 4 4 1 Inward rectifier potassium channel transmembrane domain PMP1_2 PF08114.11 CBY42534.1 - 0.069 12.9 5.9 2.1 8.2 0.9 2.5 2 0 0 2 2 2 0 ATPase proteolipid family p450 PF00067.22 CBY42536.1 - 8.8e-26 90.7 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 CBY42537.1 - 2.8e-39 135.4 0.0 3e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CBY42537.1 - 4.7e-06 26.5 0.0 1.7e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Cyclin_C PF02984.19 CBY42538.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.5 1 1 0 1 1 1 0 Cyclin, C-terminal domain PhoPQ_related PF10142.9 CBY42539.1 - 6e-51 173.2 0.1 7.6e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein bZIP_1 PF00170.21 CBY42541.1 - 0.021 14.9 0.4 0.021 14.9 0.4 1.8 2 0 0 2 2 2 0 bZIP transcription factor TH1 PF04858.13 CBY42544.1 - 8.7e-147 490.2 0.5 1.1e-146 489.9 0.5 1.0 1 0 0 1 1 1 1 TH1 protein COesterase PF00135.28 CBY42544.1 - 0.095 11.6 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family BRCT PF00533.26 CBY42546.1 - 1.8e-14 53.9 0.2 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBY42546.1 - 1.7e-13 50.3 0.0 1.3e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain BRCT_2 PF16589.5 CBY42546.1 - 1.8e-13 50.7 0.1 8.9e-12 45.3 0.1 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBY42546.1 - 7.2e-05 23.0 0.0 0.00027 21.2 0.0 1.9 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain AAA_21 PF13304.6 CBY42546.1 - 0.16 11.7 0.3 0.35 10.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Linker_histone PF00538.19 CBY42549.1 - 1.6e-07 31.6 0.1 6.3e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family PHD PF00628.29 CBY42549.1 - 0.0062 16.4 26.3 0.026 14.4 13.7 2.7 1 1 1 2 2 2 2 PHD-finger C1_1 PF00130.22 CBY42549.1 - 0.063 13.2 19.7 1.1 9.2 8.1 3.3 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_M17 PF00883.21 CBY42550.1 - 7.8e-110 367.0 0.3 1.1e-109 366.4 0.0 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CBY42550.1 - 2.1e-08 34.1 0.2 4.1e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain VKOR PF07884.14 CBY42551.1 - 2.3e-08 34.3 3.7 2.6e-08 34.1 3.7 1.0 1 0 0 1 1 1 1 Vitamin K epoxide reductase family CPBP PF02517.16 CBY42551.1 - 0.035 14.5 0.8 0.04 14.3 0.8 1.2 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease DUF3665 PF12427.8 CBY42551.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase FAD-oxidase_C PF02913.19 CBY42552.1 - 8e-59 199.3 0.0 1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBY42552.1 - 5.3e-38 129.9 0.3 8.8e-38 129.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Phospholip_A2_1 PF00068.19 CBY42553.1 - 3e-14 53.4 11.7 3e-14 53.4 11.7 2.5 2 2 0 2 2 2 1 Phospholipase A2 Dicty_REP PF05086.12 CBY42554.1 - 0.0014 16.8 0.5 0.0015 16.7 0.5 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Kelch_4 PF13418.6 CBY42554.1 - 0.0041 17.1 1.5 3.8 7.6 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY42554.1 - 0.0057 16.9 2.3 0.44 10.9 0.0 4.0 3 1 2 5 5 5 1 Kelch motif Mucin PF01456.17 CBY42554.1 - 0.028 14.4 5.9 0.053 13.5 5.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Kelch_2 PF07646.15 CBY42554.1 - 0.045 13.8 4.7 12 6.0 0.0 3.9 4 1 0 4 4 4 0 Kelch motif CCDC32 PF14989.6 CBY42554.1 - 0.046 13.7 0.2 0.097 12.7 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Kelch_5 PF13854.6 CBY42554.1 - 0.1 12.6 4.3 4.2 7.5 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DUF3439 PF11921.8 CBY42554.1 - 4.1 7.4 7.4 9.4 6.2 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Connexin PF00029.19 CBY42556.1 - 3e-36 125.4 6.2 4e-36 124.9 6.2 1.1 1 0 0 1 1 1 1 Connexin Halogen_Hydrol PF10112.9 CBY42556.1 - 0.14 12.2 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SIT PF15330.6 CBY42557.1 - 0.059 13.8 0.0 0.094 13.2 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PAG PF15347.6 CBY42557.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TMEM132D_C PF15706.5 CBY42557.1 - 0.16 11.7 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LSR PF05624.14 CBY42557.1 - 7.4 6.6 10.7 0.13 12.3 3.4 1.8 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Oxidored-like PF09791.9 CBY42558.1 - 3.1e-12 46.0 1.2 4.5e-12 45.4 1.2 1.2 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 CBY42558.1 - 0.023 14.6 1.9 0.041 13.8 1.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) EF-hand_7 PF13499.6 CBY42561.1 - 4.8e-07 30.1 0.3 1.1e-06 29.0 0.1 1.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY42561.1 - 4.3e-05 23.3 0.3 0.00014 21.7 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY42561.1 - 0.091 12.4 1.5 0.19 11.4 0.6 2.1 3 0 0 3 3 3 0 EF hand SHOCT PF09851.9 CBY42561.1 - 0.21 11.4 1.7 0.42 10.4 1.7 1.6 1 0 0 1 1 1 0 Short C-terminal domain Kelch_3 PF13415.6 CBY42562.1 - 2.2e-08 34.2 0.3 0.0038 17.5 0.1 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY42562.1 - 2.4e-08 33.6 0.3 4.6e-07 29.6 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 CBY42562.1 - 2.3e-07 30.8 0.3 6.6e-06 26.2 0.1 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CBY42562.1 - 3.8e-07 29.6 0.1 7.8e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CBY42562.1 - 3.3e-06 27.0 0.0 0.00056 19.8 0.1 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CBY42562.1 - 3.6e-06 26.9 2.7 7.7e-05 22.6 0.1 3.8 4 1 1 5 5 5 1 Galactose oxidase, central domain UL17 PF17640.2 CBY42562.1 - 0.21 11.6 0.1 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized UL17 UQ_con PF00179.26 CBY42563.1 - 3e-42 143.6 0.0 3.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AlbA_2 PF04326.14 CBY42565.1 - 2e-11 44.3 0.0 5e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Putative DNA-binding domain Cpn60_TCP1 PF00118.24 CBY42568.1 - 3.9e-79 266.6 14.1 5.8e-79 266.0 14.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family bZIP_1 PF00170.21 CBY42570.1 - 8.7e-14 51.4 12.5 2e-13 50.2 12.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY42570.1 - 2.2e-06 27.7 22.1 9.3e-06 25.6 17.9 3.0 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CBY42570.1 - 4.1e-06 27.2 14.1 4.1e-06 27.2 14.1 2.3 2 1 0 2 2 2 1 bZIP Maf transcription factor DUF3793 PF12672.7 CBY42570.1 - 0.045 13.8 0.9 0.079 13.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) WDCP PF15390.6 CBY42570.1 - 0.081 11.3 7.2 0.099 11.0 7.2 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family YabA PF06156.13 CBY42570.1 - 0.24 12.0 6.4 0.16 12.6 3.2 2.2 1 1 2 3 3 3 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 CBY42570.1 - 3 8.0 16.5 3.9e+02 1.2 16.3 2.6 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 CBY42570.1 - 3.4 7.7 16.3 1.8 8.6 12.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 CBY42570.1 - 6 7.4 11.8 0.11 12.9 2.9 2.4 1 1 1 2 2 2 0 Cell division protein ZapB PX PF00787.24 CBY42572.1 - 3.4e-17 62.5 0.0 5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 CBY42572.1 - 7.1e-14 51.9 1.1 1.2e-13 51.2 1.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY42572.1 - 3.6e-13 49.1 0.6 6.8e-13 48.3 0.6 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBY42572.1 - 3.2e-05 24.2 0.0 0.00018 21.8 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 CBY42572.1 - 0.055 13.4 0.4 1.5 8.9 0.1 2.3 1 1 1 2 2 2 0 Tricorn protease PDZ domain UFD1 PF03152.14 CBY42572.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 CRAL_TRIO PF00650.20 CBY42573.1 - 2.5e-11 43.6 0.0 3.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Hfq PF17209.3 CBY42573.1 - 0.12 12.0 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Hfq protein HA2 PF04408.23 CBY42575.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY42575.1 - 7.8e-07 29.4 0.1 1.3e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Cas_Csy3 PF09615.10 CBY42575.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) His_Phos_1 PF00300.22 CBY42576.1 - 7e-13 48.7 0.1 9.3e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fusion_gly PF00523.18 CBY42577.1 - 0.031 12.5 0.1 0.058 11.6 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 EF-hand_1 PF00036.32 CBY42579.1 - 1.1e-16 59.1 7.1 0.00031 20.1 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBY42579.1 - 2.5e-13 50.3 12.7 6.2e-10 39.4 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY42579.1 - 4.4e-13 48.1 4.5 0.00027 20.3 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 CBY42579.1 - 8e-12 44.1 7.8 0.022 14.6 0.3 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CBY42579.1 - 8.3e-06 25.6 16.6 0.017 15.0 0.0 4.4 4 1 1 5 5 5 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY42579.1 - 0.00019 21.7 5.4 0.001 19.4 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CBY42579.1 - 0.068 13.1 8.6 1.5 8.8 0.2 3.2 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 CBY42579.1 - 0.14 12.0 2.7 5.6 6.9 0.4 2.8 2 1 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 CBY42579.1 - 0.29 11.4 2.1 2.5 8.3 0.2 2.8 2 1 1 3 3 3 0 Dockerin type I domain DUF1387 PF07139.11 CBY42580.1 - 0.46 10.2 8.1 0.61 9.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RhoGAP PF00620.27 CBY42582.1 - 2e-18 66.7 0.1 2e-18 66.7 0.1 2.5 2 1 0 2 2 2 1 RhoGAP domain PRCC PF10253.9 CBY42582.1 - 0.29 11.9 8.1 0.5 11.1 8.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FXa_inhibition PF14670.6 CBY42587.1 - 0.00059 20.1 12.6 0.0025 18.0 12.6 2.1 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site MSA-2c PF12238.8 CBY42587.1 - 0.029 14.4 0.6 0.035 14.1 0.6 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Macoilin PF09726.9 CBY42587.1 - 1.8 7.0 3.9 1.9 7.0 3.9 1.0 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CBY42587.1 - 8.9 4.5 11.3 9.7 4.3 11.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ctf8 PF09696.10 CBY42588.1 - 3.7e-11 43.5 0.6 5e-09 36.6 0.6 2.2 1 1 0 1 1 1 1 Ctf8 TraB PF01963.17 CBY42591.1 - 3.5e-17 63.2 0.2 4.7e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 TraB family Sarcoglycan_1 PF04790.13 CBY42591.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Glyco_transf_64 PF09258.10 CBY42595.1 - 9.8e-26 90.5 0.2 1.5e-25 89.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Exostosin PF03016.15 CBY42595.1 - 4.4e-05 22.8 0.0 6.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Exostosin family GATase_6 PF13522.6 CBY42596.1 - 1.3e-15 57.8 0.0 2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBY42596.1 - 3.6e-10 39.8 0.0 5.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CBY42596.1 - 0.00044 19.3 0.0 0.00068 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SR-25 PF10500.9 CBY42598.1 - 0.07 12.7 8.3 0.082 12.5 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_A32 PF04665.12 CBY42599.1 - 0.00048 19.7 1.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein ATPase PF06745.13 CBY42599.1 - 0.0026 17.1 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 KaiC TraG-D_C PF12696.7 CBY42599.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Sigma54_activat PF00158.26 CBY42599.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBY42599.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 CBY42599.1 - 0.018 14.2 0.0 0.08 12.1 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 CBY42599.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY42599.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CBY42599.1 - 0.038 13.7 0.0 8.3 6.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 CBY42599.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBY42599.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBY42599.1 - 0.16 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY42599.1 - 0.24 11.8 0.0 0.57 10.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBY42601.1 - 1.2e-38 132.5 0.0 2.8e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY42601.1 - 2.4e-07 30.6 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBY42601.1 - 2.4e-07 31.0 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBY42601.1 - 1.1e-06 28.7 0.0 5.5e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBY42601.1 - 3.2e-06 27.6 0.4 6.3e-05 23.4 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBY42601.1 - 5.9e-05 23.4 1.7 0.0099 16.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CBY42601.1 - 6.1e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBY42601.1 - 0.00061 20.3 0.5 0.016 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBY42601.1 - 0.0011 18.3 0.0 0.0028 16.9 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CBY42601.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBY42601.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBY42601.1 - 0.0049 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CBY42601.1 - 0.0064 15.9 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.11 CBY42601.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CBY42601.1 - 0.009 15.5 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 CBY42601.1 - 0.012 15.4 3.7 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBY42601.1 - 0.013 15.3 0.0 0.094 12.4 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 CBY42601.1 - 0.016 14.9 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY42601.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY42601.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HOOK PF05622.12 CBY42601.1 - 0.03 12.5 5.3 0.04 12.1 5.3 1.1 1 0 0 1 1 1 0 HOOK protein TsaE PF02367.17 CBY42601.1 - 0.031 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CBY42601.1 - 0.034 13.3 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CBY42601.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CBY42601.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBY42601.1 - 0.043 14.1 0.0 0.39 11.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBY42601.1 - 0.045 14.2 0.1 0.27 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBY42601.1 - 0.048 13.2 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBY42601.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 CBY42601.1 - 0.28 11.4 1.7 0.59 10.4 1.7 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein RILP PF11461.8 CBY42601.1 - 0.28 11.4 4.5 0.4 10.9 2.9 2.1 1 1 1 2 2 2 0 Rab interacting lysosomal protein Spc24 PF08286.11 CBY42601.1 - 0.53 10.6 4.1 0.72 10.1 2.1 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Neur_chan_LBD PF02931.23 CBY42602.1 - 1.7e-16 60.4 0.0 2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain AFT PF08731.11 CBY42603.1 - 0.0045 17.4 0.5 0.0096 16.3 0.5 1.5 1 0 0 1 1 1 1 Transcription factor AFT Med26_C PF15693.5 CBY42603.1 - 0.083 13.0 1.9 0.12 12.5 1.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal VWA PF00092.28 CBY42604.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Sushi PF00084.20 CBY42604.1 - 0.022 15.4 3.6 0.065 13.8 3.6 1.9 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) Sulfatase PF00884.23 CBY42606.1 - 2.6e-31 109.2 0.5 3e-31 108.9 0.5 1.0 1 0 0 1 1 1 1 Sulfatase Gal-3-0_sulfotr PF06990.11 CBY42607.1 - 2.8e-45 154.9 0.5 3.5e-45 154.6 0.5 1.1 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 CBY42607.1 - 2.9e-08 33.9 0.4 1.6e-07 31.5 0.4 1.9 1 1 0 1 1 1 1 Sulfotransferase family GARS_A PF01071.19 CBY42608.1 - 0.072 12.8 0.1 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DNA_pol3_a_NII PF11490.8 CBY42608.1 - 0.089 12.7 3.0 0.21 11.5 3.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Acyl-CoA_dh_1 PF00441.24 CBY42609.1 - 3.8e-40 137.5 0.7 5.1e-40 137.1 0.7 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBY42609.1 - 1.6e-21 76.3 0.0 2.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBY42609.1 - 3.2e-13 50.1 0.0 5.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3029 PF11230.8 CBY42609.1 - 0.097 11.0 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) ER_lumen_recept PF00810.18 CBY42611.1 - 3.2e-52 177.3 9.9 5.6e-52 176.5 9.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CBY42611.1 - 0.015 15.0 7.0 0.5 10.2 0.7 3.1 2 1 1 3 3 3 0 PQ loop repeat Peptidase_M24 PF00557.24 CBY42612.1 - 6.1e-34 117.5 0.0 7.5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CBY42612.1 - 1.3e-14 54.0 0.4 2e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 SGT1 PF07093.11 CBY42612.1 - 0.016 13.7 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 SGT1 protein DnaJ PF00226.31 CBY42613.1 - 2.2e-16 59.7 0.1 6.5e-16 58.2 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain PH_4 PF15404.6 CBY42613.1 - 0.4 10.5 6.9 0.074 12.9 1.8 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain Sdh_cyt PF01127.22 CBY42614.1 - 0.014 15.5 0.2 0.016 15.2 0.2 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SLAC1 PF03595.17 CBY42614.1 - 0.016 14.5 0.4 0.019 14.2 0.4 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF2976 PF11190.8 CBY42614.1 - 0.1 12.4 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) SET PF00856.28 CBY42615.1 - 3.7e-13 50.2 0.3 7.3e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 SET domain BAR_3 PF16746.5 CBY42620.1 - 3.1e-56 190.7 14.8 3.9e-56 190.4 14.8 1.1 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CBY42620.1 - 9.6e-08 32.5 2.0 1.7e-06 28.5 0.2 2.6 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 CBY42622.1 - 0.0038 17.8 0.0 0.0048 17.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY42622.1 - 0.0069 16.8 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CBY42622.1 - 0.014 15.9 0.0 0.021 15.4 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) VWA_3_C PF18571.1 CBY42622.1 - 0.03 14.2 0.1 0.07 13.0 0.1 1.6 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain Foie-gras_1 PF11817.8 CBY42622.1 - 0.093 12.3 0.0 0.093 12.3 0.0 1.0 1 0 0 1 1 1 0 Foie gras liver health family 1 RNA_pol_Rpb4 PF03874.16 CBY42622.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 Alpha_L_fucos PF01120.17 CBY42624.1 - 4.5e-37 128.3 0.2 9.4e-37 127.3 0.0 1.6 2 0 0 2 2 2 1 Alpha-L-fucosidase PIP5K PF01504.18 CBY42626.1 - 1.6e-30 106.3 2.1 2e-30 106.0 2.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MFS_1 PF07690.16 CBY42627.1 - 7.5e-08 31.7 6.1 8.6e-08 31.5 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY42627.1 - 0.0037 16.2 1.4 0.0041 16.0 1.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Carn_acyltransf PF00755.20 CBY42634.1 - 1.2e-13 50.6 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-3CxxC_2 PF17180.4 CBY42635.1 - 3.5e-23 82.1 7.5 3.5e-23 82.1 7.5 4.2 3 1 1 4 4 4 1 Zinc-binding domain zf-DBF PF07535.12 CBY42635.1 - 0.042 14.0 0.8 0.042 14.0 0.8 3.6 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_jaz PF12171.8 CBY42635.1 - 0.23 11.8 0.4 0.23 11.8 0.4 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding TCP PF03634.13 CBY42636.1 - 0.04 14.5 0.2 0.09 13.3 0.0 1.6 1 1 0 1 1 1 0 TCP family transcription factor DUF4755 PF15947.5 CBY42639.1 - 0.07 13.1 0.6 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4755) Pkinase PF00069.25 CBY42640.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Orthoreo_P10 PF07204.11 CBY42644.1 - 0.035 14.1 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Prok-TraM PF09228.10 CBY42644.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM SR-25 PF10500.9 CBY42644.1 - 0.27 10.8 26.5 0.65 9.6 12.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAF PF02961.14 CBY42645.1 - 1.6e-20 73.3 0.2 2.6e-20 72.6 0.2 1.3 1 0 0 1 1 1 1 Barrier to autointegration factor Tub PF01167.18 CBY42646.1 - 3.6e-49 167.7 0.1 3.9e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 CBY42646.1 - 0.014 15.0 0.1 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3527) zf-RING_UBOX PF13445.6 CBY42648.1 - 0.00014 21.8 6.9 0.00014 21.8 6.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Zn-C2H2_12 PF18112.1 CBY42648.1 - 0.00057 20.3 3.9 0.018 15.5 0.4 2.5 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 CBY42648.1 - 0.00085 19.4 8.4 0.00085 19.4 8.4 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Tropomyosin_1 PF12718.7 CBY42648.1 - 0.0033 17.6 10.4 0.0044 17.2 10.4 1.3 1 0 0 1 1 1 1 Tropomyosin like ATG16 PF08614.11 CBY42648.1 - 0.0036 17.6 7.8 0.005 17.1 7.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 CBY42648.1 - 0.013 15.6 5.8 0.019 15.1 5.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-RING_5 PF14634.6 CBY42648.1 - 0.019 14.9 18.1 0.11 12.4 18.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY42648.1 - 0.019 14.8 16.5 0.44 10.5 16.7 2.8 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 CBY42648.1 - 0.051 13.1 3.3 0.052 13.1 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 CBY42648.1 - 0.053 14.1 1.3 0.1 13.2 1.1 1.7 1 1 0 1 1 1 0 SlyX Spc7 PF08317.11 CBY42648.1 - 0.055 12.4 7.9 0.068 12.0 7.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_2 PF13639.6 CBY42648.1 - 0.057 13.8 16.3 1.1 9.7 16.4 2.3 1 1 0 1 1 1 0 Ring finger domain UPF0242 PF06785.11 CBY42648.1 - 0.12 12.5 9.5 0.18 11.9 9.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CaKB PF03185.15 CBY42648.1 - 0.13 12.0 4.6 0.24 11.0 4.6 1.4 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Atg14 PF10186.9 CBY42648.1 - 0.23 10.5 8.7 0.28 10.2 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vps5 PF09325.10 CBY42648.1 - 0.37 10.3 11.5 0.43 10.1 7.1 2.2 1 1 1 2 2 2 0 Vps5 C terminal like DUF3450 PF11932.8 CBY42648.1 - 0.57 9.4 6.2 0.87 8.8 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 CBY42648.1 - 0.6 10.1 16.7 1.6 8.8 12.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 CBY42648.1 - 0.82 9.0 3.2 1.1 8.5 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 CBY42648.1 - 1.1 8.1 2.6 1.1 8.1 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 CBY42648.1 - 1.7 7.8 7.1 2.1 7.5 7.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 CBY42648.1 - 1.9 7.0 8.5 2.6 6.6 8.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CBY42648.1 - 1.9 6.3 5.4 2 6.3 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C3HC4_2 PF13923.6 CBY42648.1 - 2.9 7.8 19.1 0.25 11.2 9.6 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4140 PF13600.6 CBY42648.1 - 6.6 7.2 6.6 5.2 7.6 3.7 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 CBY42648.1 - 6.7 7.2 10.3 4.3 7.8 7.7 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3847 PF12958.7 CBY42648.1 - 8.6 6.6 10.2 0.99 9.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Rho_Binding PF08912.11 CBY42648.1 - 9.6 7.1 14.2 12 6.8 8.5 2.4 1 1 1 2 2 2 0 Rho Binding Orexin_rec2 PF03827.13 CBY42650.1 - 0.046 13.7 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Orexin receptor type 2 DDRGK PF09756.9 CBY42651.1 - 0.015 14.9 8.5 0.018 14.6 8.5 1.2 1 0 0 1 1 1 0 DDRGK domain PBP1_TM PF14812.6 CBY42651.1 - 0.15 12.5 4.6 0.26 11.7 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Crystall PF00030.19 CBY42653.1 - 2.5e-12 46.8 0.1 9.5e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Beta/Gamma crystallin TMEM154 PF15102.6 CBY42656.1 - 0.0019 18.1 0.6 0.0022 17.9 0.6 1.1 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 CBY42656.1 - 0.0023 18.8 0.5 0.0031 18.4 0.5 1.1 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 CBY42656.1 - 0.014 15.2 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.12 CBY42656.1 - 0.024 14.2 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family NB PF04159.13 CBY42656.1 - 0.056 13.5 0.9 0.068 13.2 0.9 1.1 1 0 0 1 1 1 0 NB glycoprotein DUF1616 PF07760.11 CBY42656.1 - 0.074 12.4 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Insulin_TMD PF17870.1 CBY42656.1 - 0.11 12.6 0.6 0.16 12.1 0.6 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment S_4TM PF18159.1 CBY42656.1 - 0.15 11.3 1.7 0.42 9.9 0.3 1.8 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain FixS PF03597.15 CBY42656.1 - 1.2 8.9 5.2 0.55 10.0 2.9 1.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2116 PF09889.9 CBY42656.1 - 2 8.4 6.9 6.5 6.8 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TRP_2 PF08344.11 CBY42659.1 - 4.2e-14 52.5 2.9 7.4e-14 51.7 2.9 1.4 1 0 0 1 1 1 1 Transient receptor ion channel II zf-RING_2 PF13639.6 CBY42660.1 - 6.2e-09 36.1 8.3 6.2e-09 36.1 8.3 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY42660.1 - 6.4e-09 35.5 9.6 1.9e-08 34.0 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY42660.1 - 2e-08 33.9 5.1 2e-08 33.9 5.1 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY42660.1 - 6.8e-08 32.3 9.0 6.8e-08 32.3 9.0 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY42660.1 - 1.5e-07 31.3 5.0 1.5e-07 31.3 5.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY42660.1 - 1.1e-06 28.5 8.0 1.1e-06 28.5 8.0 2.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_4 PF14570.6 CBY42660.1 - 7.9e-06 25.6 6.6 7.9e-06 25.6 6.6 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CBY42660.1 - 0.00017 21.4 5.1 0.00017 21.4 5.1 2.8 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CBY42660.1 - 0.023 14.4 3.0 0.023 14.4 3.0 2.5 1 1 1 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBY42660.1 - 0.032 14.4 10.1 0.032 14.4 10.1 2.6 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 CBY42660.1 - 0.045 14.2 2.9 1.3 9.6 0.3 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF1272 PF06906.11 CBY42660.1 - 0.67 10.1 12.5 0.26 11.4 8.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 CBY42660.1 - 1.2 9.2 7.4 0.79 9.9 5.1 1.9 2 1 0 2 2 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 CBY42660.1 - 1.4 8.9 15.5 0.38 10.7 9.8 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY42660.1 - 3.3 7.9 13.7 0.046 13.9 4.2 2.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 MalF_P2 PF14785.6 CBY42661.1 - 0.00088 19.3 0.7 0.01 15.9 0.2 2.5 2 0 0 2 2 2 1 Maltose transport system permease protein MalF P2 domain KxDL PF10241.9 CBY42661.1 - 0.84 10.0 7.6 11 6.3 0.0 4.3 5 0 0 5 5 5 0 Uncharacterized conserved protein CAP PF00188.26 CBY42662.1 - 2.8e-07 31.4 0.2 9.2e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zf-HIT PF04438.16 CBY42662.1 - 4.8 7.1 10.4 0.94 9.4 1.2 3.4 3 0 0 3 3 3 0 HIT zinc finger Ion_trans PF00520.31 CBY42663.1 - 1.3e-22 80.3 10.0 2.2e-22 79.5 10.0 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CBY42663.1 - 0.0011 17.8 10.8 0.0011 17.8 10.8 1.7 2 1 0 2 2 2 1 Polycystin cation channel UCH PF00443.29 CBY42666.1 - 5.1e-25 88.4 0.0 7.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBY42666.1 - 9.6e-05 22.1 0.0 0.031 13.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cauli_AT PF03233.13 CBY42666.1 - 0.074 13.0 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Aphid transmission protein HSP70 PF00012.20 CBY42667.1 - 1.5e-38 132.4 0.0 1.7e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 CBY42668.1 - 2.9e-167 557.5 5.8 9.3e-138 460.0 2.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CBY42668.1 - 8.3e-19 67.6 0.3 4.2e-18 65.2 0.3 1.9 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CBY42668.1 - 2.4e-05 24.2 0.0 8.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CBY42668.1 - 0.0089 15.1 6.7 0.049 12.6 0.1 3.3 3 1 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 CBY42668.1 - 0.023 15.1 0.1 3.5 8.1 0.2 2.9 2 2 0 2 2 2 0 Cell division protein FtsA PilM_2 PF11104.8 CBY42668.1 - 0.07 12.2 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; StbA PF06406.11 CBY42668.1 - 0.081 12.1 0.2 0.21 10.8 0.0 1.7 3 0 0 3 3 3 0 StbA protein Hydantoinase_A PF01968.18 CBY42668.1 - 0.16 11.2 3.3 1.3 8.3 0.1 2.8 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase zf-LITAF-like PF10601.9 CBY42669.1 - 0.52 10.6 32.5 0.24 11.7 7.8 4.1 4 1 0 4 4 4 0 LITAF-like zinc ribbon domain Pkinase PF00069.25 CBY42674.1 - 2.9e-08 33.4 0.5 1.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42674.1 - 0.0014 18.0 0.1 0.006 15.9 0.1 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase NAD_binding_1 PF00175.21 CBY42675.1 - 2.2e-28 99.1 0.0 3.1e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBY42675.1 - 3.9e-27 94.5 0.0 6.6e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBY42675.1 - 7.8e-05 22.9 0.0 0.00044 20.4 0.0 1.9 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CBY42675.1 - 0.019 15.2 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DEAD PF00270.29 CBY42676.1 - 5.3e-24 84.9 0.0 7.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY42676.1 - 0.00023 21.2 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CBY42678.1 - 1.4e-09 37.6 7.0 1.4e-09 37.6 7.0 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY42678.1 - 1.8e-09 37.5 6.8 1.8e-09 37.5 6.8 2.3 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY42678.1 - 8.7e-07 28.8 8.1 8.7e-07 28.8 8.1 2.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY42678.1 - 1.4e-06 28.0 7.7 1.4e-06 28.0 7.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 CBY42678.1 - 1.5e-06 28.2 5.9 1.5e-06 28.2 5.9 3.0 4 0 0 4 4 3 1 B-box zinc finger zf-RING_2 PF13639.6 CBY42678.1 - 1.6e-06 28.3 8.4 1.6e-06 28.3 8.4 2.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY42678.1 - 2.1e-05 24.3 11.4 2.1e-05 24.3 11.4 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY42678.1 - 2.3e-05 24.5 7.5 2.3e-05 24.5 7.5 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CBY42678.1 - 0.00012 21.8 2.8 0.00012 21.8 2.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein HGD-D PF06050.13 CBY42678.1 - 0.015 15.1 0.5 0.02 14.7 0.5 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF29 PF01724.16 CBY42678.1 - 0.041 14.1 1.4 0.075 13.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 T3SchapCesA PF11439.8 CBY42678.1 - 0.061 13.5 0.3 0.23 11.6 0.1 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA AKNA PF12443.8 CBY42678.1 - 0.084 13.5 1.5 0.23 12.1 1.5 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor Fzo_mitofusin PF04799.13 CBY42678.1 - 0.091 12.3 6.4 3.8 7.0 0.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region Gp-FAR-1 PF05823.12 CBY42678.1 - 0.14 12.5 4.2 1.1 9.6 0.4 2.8 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF326 PF03860.16 CBY42678.1 - 0.17 11.9 3.9 0.66 10.0 3.9 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) zf-RING_11 PF17123.5 CBY42678.1 - 0.17 11.7 5.0 0.68 9.7 5.0 2.1 1 0 0 1 1 1 0 RING-like zinc finger Spectrin PF00435.21 CBY42678.1 - 1.2 9.7 6.1 1.1 9.8 2.7 2.3 2 0 0 2 2 2 0 Spectrin repeat DHR10 PF18595.1 CBY42678.1 - 1.6 8.8 11.1 5.7 7.0 3.0 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Uso1_p115_C PF04871.13 CBY42678.1 - 1.7 9.0 6.5 3.4 8.0 6.5 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region OrfB_Zn_ribbon PF07282.11 CBY42678.1 - 4.1 7.4 7.2 0.43 10.5 1.2 2.4 3 0 0 3 3 2 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 CBY42678.1 - 5.1 7.7 0.0 5.1 7.7 0.0 3.5 4 0 0 4 4 2 0 Zinc-finger double domain OmpH PF03938.14 CBY42678.1 - 7.5 6.9 13.0 11 6.4 5.8 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) zf-RING_10 PF16685.5 CBY42678.1 - 7.6 6.7 16.7 0.29 11.3 4.9 2.9 3 0 0 3 3 2 0 zinc RING finger of MSL2 LapA_dom PF06305.11 CBY42679.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Dpy19 PF10034.9 CBY42679.1 - 0.07 11.3 0.0 0.088 11.0 0.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation PMT_4TMC PF16192.5 CBY42679.1 - 0.077 12.6 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase Peptidase_C57 PF03290.13 CBY42680.1 - 0.096 11.4 0.3 0.11 11.2 0.3 1.0 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase AMMECR1 PF01871.17 CBY42681.1 - 1.6e-18 66.9 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Sas6_CC PF18594.1 CBY42681.1 - 0.091 12.6 1.6 0.19 11.5 1.6 1.5 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain TAN PF11640.8 CBY42682.1 - 0.072 13.2 0.3 0.072 13.2 0.3 1.5 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Glycos_transf_2 PF00535.26 CBY42683.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Zona_pellucida PF00100.23 CBY42684.1 - 6.4e-23 81.9 2.8 6.4e-23 81.9 2.8 1.4 2 0 0 2 2 2 1 Zona pellucida-like domain NKWYS PF10364.9 CBY42684.1 - 0.038 14.1 0.8 0.094 12.8 0.8 1.7 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein APH PF01636.23 CBY42685.1 - 0.1 12.5 0.2 0.12 12.2 0.2 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family PITH PF06201.13 CBY42687.1 - 9.3e-12 45.4 0.0 1.3e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 PITH domain NADH_B2 PF14813.6 CBY42688.1 - 0.018 14.8 1.1 0.043 13.6 1.1 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 CDV3 PF15359.6 CBY42688.1 - 0.12 12.8 1.1 0.2 12.1 1.1 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Peptidase_C78 PF07910.13 CBY42689.1 - 3e-47 160.8 0.1 5e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBY42689.1 - 0.0016 17.9 1.6 0.12 11.8 0.5 2.8 1 1 1 2 2 2 2 Peptidase family C54 Sterile PF03015.19 CBY42689.1 - 0.082 13.1 2.2 0.31 11.3 0.1 2.9 4 0 0 4 4 4 0 Male sterility protein Kelch_6 PF13964.6 CBY42692.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Methyltransf_15 PF09445.10 CBY42692.1 - 0.029 13.9 0.0 0.032 13.8 0.0 1.0 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase WD40 PF00400.32 CBY42693.1 - 0.098 13.6 2.4 0.63 11.0 0.2 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat OSTbeta PF15048.6 CBY42693.1 - 0.49 10.6 2.7 0.81 9.8 2.7 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein zf-rbx1 PF12678.7 CBY42696.1 - 3e-19 69.0 14.4 4e-19 68.7 14.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBY42696.1 - 7.3e-16 58.0 16.1 8.3e-16 57.8 16.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBY42696.1 - 9e-05 22.7 22.4 0.0042 17.4 22.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY42696.1 - 0.0037 17.1 15.0 0.015 15.1 15.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY42696.1 - 0.014 15.2 12.9 0.014 15.2 12.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY42696.1 - 0.34 10.8 17.8 0.05 13.5 9.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.6 CBY42697.1 - 1.8e-11 44.3 0.0 0.026 14.9 0.0 4.4 1 1 1 3 3 3 3 HEAT repeats Arm PF00514.23 CBY42697.1 - 2.7e-08 33.6 0.2 0.0085 16.1 0.1 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBY42697.1 - 4.5e-07 29.6 7.2 7.3 7.1 0.3 6.9 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 CBY42697.1 - 7.1e-06 24.9 3.5 2.7e-05 22.9 3.5 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBY42697.1 - 0.00049 20.2 5.2 0.067 13.2 0.2 3.1 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 CBY42697.1 - 0.0026 16.9 3.7 0.49 9.4 0.1 2.7 1 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 CBY42697.1 - 0.02 15.4 1.6 8.5 7.0 0.0 4.3 7 0 0 7 7 7 0 HEAT-like repeat Gcn1_N PF12074.8 CBY42697.1 - 0.049 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Vac14_Fab1_bd PF12755.7 CBY42697.1 - 0.054 14.1 0.6 20 5.9 0.1 3.3 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region CHGN PF05679.16 CBY42698.1 - 2.6e-07 29.9 0.2 2.7e-07 29.8 0.2 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Mucin PF01456.17 CBY42699.1 - 0.0088 16.0 18.6 0.018 15.1 18.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Kelch_6 PF13964.6 CBY42699.1 - 0.43 10.9 2.6 1.8 9.0 0.0 2.9 3 1 1 4 4 4 0 Kelch motif UBA PF00627.31 CBY42700.1 - 8.1e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF1421 PF07223.11 CBY42700.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) CUE PF02845.16 CBY42701.1 - 2.1e-06 27.3 0.3 4.6e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 CUE domain G2BR PF18442.1 CBY42701.1 - 0.0084 15.7 0.6 0.02 14.5 0.6 1.6 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Collagen PF01391.18 CBY42704.1 - 6.6e-32 109.1 121.5 2.3e-10 40.0 25.7 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) VWA_2 PF13519.6 CBY42704.1 - 0.033 14.8 0.0 0.054 14.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain LRR_8 PF13855.6 CBY42705.1 - 9e-21 73.4 21.7 1.9e-11 43.5 5.4 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBY42705.1 - 4.4e-10 39.7 21.0 4.9e-06 26.8 2.7 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBY42705.1 - 2.9e-05 23.6 5.0 0.00075 19.0 2.3 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 CBY42705.1 - 5.2e-05 23.2 0.4 0.0001 22.3 0.4 1.5 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Ig_3 PF13927.6 CBY42705.1 - 0.00025 21.6 0.0 0.00047 20.7 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY42705.1 - 0.00048 20.4 0.1 0.00077 19.8 0.1 1.3 1 0 0 1 1 1 1 Immunoglobulin domain LRR_1 PF00560.33 CBY42705.1 - 0.00092 19.4 8.3 11 7.1 0.0 4.9 3 2 1 4 4 4 1 Leucine Rich Repeat I-set PF07679.16 CBY42705.1 - 0.0054 16.8 0.1 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Immunoglobulin I-set domain DUF2207 PF09972.9 CBY42706.1 - 0.034 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SID-1_RNA_chan PF13965.6 CBY42706.1 - 0.072 11.5 0.0 0.092 11.1 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MFS_2 PF13347.6 CBY42706.1 - 0.1 11.1 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein EphA2_TM PF14575.6 CBY42706.1 - 0.17 12.8 0.5 0.54 11.2 0.5 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-C4 PF00105.18 CBY42707.1 - 5.3e-32 110.1 12.4 9.8e-32 109.2 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY42707.1 - 1.6e-07 31.1 0.0 4.9e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TMCO5 PF14992.6 CBY42707.1 - 0.12 12.0 1.7 0.2 11.2 1.7 1.3 1 0 0 1 1 1 0 TMCO5 family TP6A_N PF04406.14 CBY42707.1 - 0.13 12.3 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Type IIB DNA topoisomerase DUF3736 PF12540.8 CBY42707.1 - 0.15 12.1 5.6 0.19 11.8 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) TFIIA PF03153.13 CBY42707.1 - 1.7 8.5 13.6 2.7 7.9 13.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIBIOP_C PF04950.12 CBY42708.1 - 3e-84 282.9 0.3 3e-84 282.9 0.3 2.2 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AAA_21 PF13304.6 CBY42708.1 - 0.38 10.5 2.6 0.98 9.2 2.6 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FAST_2 PF08368.12 CBY42709.1 - 0.034 14.9 0.2 0.11 13.3 0.2 2.0 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DAGK_acc PF00609.19 CBY42712.1 - 3.2e-41 141.3 0.7 7.1e-41 140.2 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain SAM_2 PF07647.17 CBY42712.1 - 0.00013 22.0 0.1 0.0003 20.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF29 PF01724.16 CBY42712.1 - 0.78 10.0 4.4 27 5.0 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF29 DUF2408 PF10303.9 CBY42712.1 - 2.2 8.9 7.8 0.58 10.7 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AAA_6 PF12774.7 CBY42716.1 - 1.5e-67 227.9 0.0 2.4e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DUF327 PF03885.13 CBY42716.1 - 0.079 12.9 0.7 0.14 12.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) Ribosomal_L14e PF01929.17 CBY42716.1 - 0.14 12.7 1.1 0.29 11.6 0.3 1.9 2 0 0 2 2 2 0 Ribosomal protein L14 OSCP PF00213.18 CBY42718.1 - 1.9e-36 125.8 0.2 2.4e-36 125.5 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF726 PF05277.12 CBY42718.1 - 0.078 11.9 0.4 0.088 11.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Ribosomal_L6 PF00347.23 CBY42719.1 - 2.2e-27 95.5 1.7 9.8e-14 51.8 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Kelch_5 PF13854.6 CBY42721.1 - 0.00038 20.4 0.0 0.00038 20.4 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CBY42721.1 - 0.0084 16.1 1.8 0.34 10.9 0.1 2.8 3 0 0 3 3 3 2 Kelch motif TIL PF01826.17 CBY42722.1 - 1e-05 25.7 23.7 6.9e-05 23.0 13.6 2.5 2 0 0 2 2 2 2 Trypsin Inhibitor like cysteine rich domain Trypsin PF00089.26 CBY42723.1 - 6.8e-39 134.0 0.1 1.3e-38 133.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin PLAT PF01477.23 CBY42726.1 - 0.0016 19.0 3.4 0.048 14.2 0.3 3.3 3 1 0 3 3 3 1 PLAT/LH2 domain CXCL17 PF15211.6 CBY42726.1 - 0.015 16.1 0.0 0.032 15.0 0.0 1.5 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 PLAT PF01477.23 CBY42727.1 - 0.00011 22.7 0.0 0.00014 22.4 0.0 1.2 1 0 0 1 1 1 1 PLAT/LH2 domain TPR_14 PF13428.6 CBY42728.1 - 4.6e-27 92.4 24.3 0.0013 19.4 0.2 12.5 4 3 9 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 CBY42728.1 - 4.6e-23 81.5 17.2 1e-06 29.1 0.2 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBY42728.1 - 1.4e-14 54.4 0.8 0.017 15.8 0.2 6.3 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBY42728.1 - 3.3e-11 42.8 1.8 0.028 14.8 0.1 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 CBY42728.1 - 6.8e-07 29.6 0.1 0.0019 18.3 0.0 3.5 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 CBY42728.1 - 5e-06 26.2 12.6 4.3 7.7 0.0 9.4 11 1 0 12 12 12 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBY42728.1 - 5.3e-05 23.1 11.2 0.059 13.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 CBY42728.1 - 8.8e-05 22.4 1.5 2.6 8.1 0.1 4.2 3 1 1 4 4 4 1 ZNRF-3 Ectodomain ChAPs PF09295.10 CBY42728.1 - 0.0063 15.6 5.4 1.1 8.1 0.3 3.2 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.6 CBY42728.1 - 0.056 13.1 2.4 1.3 8.8 0.0 4.3 4 1 2 6 6 6 0 TPR repeat TPR_6 PF13174.6 CBY42728.1 - 2 9.2 16.6 1.7e+02 3.1 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBY42728.1 - 2 8.3 8.5 9.6 6.2 0.0 4.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Thioredoxin_16 PF18569.1 CBY42729.1 - 0.84 9.8 5.6 0.82 9.8 1.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain DHR-2 PF06920.13 CBY42730.1 - 1.5e-40 139.3 0.1 1.7e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Dock homology region 2 zf-CDGSH PF09360.10 CBY42730.1 - 0.17 12.1 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Iron-binding zinc finger CDGSH type Ank_2 PF12796.7 CBY42731.1 - 2.9e-29 101.5 0.0 1.8e-13 50.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY42731.1 - 9e-21 74.0 0.0 2.8e-07 31.0 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY42731.1 - 2.7e-19 68.9 0.0 2.4e-07 30.9 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY42731.1 - 8.7e-19 65.7 0.0 0.00022 21.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 CBY42731.1 - 5.5e-14 51.9 0.0 0.0069 16.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat REV PF00424.18 CBY42733.1 - 0.099 12.7 0.2 0.37 10.8 0.2 2.0 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) PSI_integrin PF17205.3 CBY42734.1 - 3.2e-07 30.0 9.7 4.9e-07 29.4 9.7 1.3 1 0 0 1 1 1 1 Integrin plexin domain PSI PF01437.25 CBY42734.1 - 8.4e-05 23.0 5.0 0.00012 22.5 5.0 1.2 1 0 0 1 1 1 1 Plexin repeat Scramblase PF03803.15 CBY42736.1 - 1.4e-18 67.0 0.0 2.4e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Scramblase Pkinase PF00069.25 CBY42738.1 - 2e-09 37.2 0.1 3.1e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42738.1 - 8.7e-07 28.5 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3896 PF13035.6 CBY42738.1 - 0.018 15.2 3.3 2.6 8.3 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) DUF1827 PF08860.10 CBY42738.1 - 0.11 12.7 0.5 8.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) COesterase PF00135.28 CBY42742.1 - 1.1e-88 298.4 0.1 1.3e-88 298.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY42742.1 - 9.2e-08 32.2 1.5 2.7e-07 30.7 1.5 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY42742.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBY42742.1 - 0.039 14.6 0.1 0.07 13.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 CBY42742.1 - 0.079 11.8 0.1 0.26 10.1 0.1 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase zf-RING_5 PF14634.6 CBY42745.1 - 0.00027 20.8 5.4 0.0065 16.4 0.2 2.9 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 CBY42745.1 - 0.0086 16.4 5.4 0.025 14.9 0.0 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY42745.1 - 0.0099 15.9 4.7 0.85 9.7 0.1 3.2 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBY42745.1 - 0.011 15.6 2.3 0.043 13.7 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YscO-like PF16789.5 CBY42745.1 - 0.011 15.8 12.6 0.016 15.2 12.6 1.2 1 0 0 1 1 1 0 YscO-like protein zf-RING_11 PF17123.5 CBY42745.1 - 0.029 14.1 0.9 0.068 12.9 0.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 CBY42745.1 - 0.12 12.3 5.7 0.5 10.3 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ApoO PF09769.9 CBY42745.1 - 0.15 12.0 0.5 0.25 11.3 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein O V_ATPase_I PF01496.19 CBY42745.1 - 1.9 6.3 6.1 2.4 6.0 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CBY42745.1 - 2.4 7.0 4.3 2.8 6.8 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_16 PF00722.21 CBY42746.1 - 1.8e-16 60.1 2.1 1.8e-16 60.1 2.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FSA_C PF10479.9 CBY42746.1 - 0.52 8.4 2.6 0.67 8.0 2.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Polysacc_synt_C PF14667.6 CBY42747.1 - 0.019 15.1 2.5 0.023 14.8 2.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain SAM_1 PF00536.30 CBY42748.1 - 3.3e-10 40.2 0.0 5.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBY42748.1 - 1.3e-09 38.0 0.2 2.2e-09 37.3 0.2 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CBY42748.1 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CBY42748.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) zf_Rg PF17915.1 CBY42748.1 - 0.022 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse gyrase zinc finger BTB_2 PF02214.22 CBY42749.1 - 1.1e-18 67.4 0.0 1.3e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 CBY42749.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 BTB/POZ domain PS_Dcarbxylase PF02666.15 CBY42751.1 - 3.2e-65 219.4 0.0 3.8e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 CBY42751.1 - 0.014 15.6 0.1 4.7 7.5 0.1 3.0 2 1 1 3 3 3 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 CBY42751.1 - 0.064 13.0 0.1 14 5.4 0.0 2.9 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Flg_new PF09479.10 CBY42752.1 - 0.068 13.4 0.4 0.14 12.4 0.4 1.4 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Galactosyl_T PF01762.21 CBY42758.1 - 9.2e-20 71.3 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase COesterase PF00135.28 CBY42759.1 - 3.3e-12 46.0 0.0 3.9e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family XRN_N PF03159.18 CBY42760.1 - 0.0059 16.1 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Pkinase PF00069.25 CBY42761.1 - 3e-09 36.6 0.1 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42761.1 - 8.5e-06 25.2 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY42761.1 - 3.2e-05 22.9 0.0 5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PT-VENN PF04829.13 CBY42761.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif DUF4110 PF13422.6 CBY42762.1 - 1.1e-05 25.4 0.7 1.1e-05 25.4 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 CBY42762.1 - 4.4e-05 23.4 0.0 6.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY42762.1 - 5.2e-05 23.4 0.8 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY42762.1 - 0.00016 21.8 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.6 CBY42762.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.15 CBY42762.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.25 CBY42762.1 - 0.049 13.2 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Cullin PF00888.22 CBY42763.1 - 1.4e-64 218.9 0.4 1.5e-64 218.7 0.4 1.0 1 0 0 1 1 1 1 Cullin family SpoIIE PF07228.12 CBY42764.1 - 5.6e-05 23.2 0.0 6.2e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Rad51 PF08423.11 CBY42765.1 - 2.6e-113 377.5 0.1 4.1e-113 376.9 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBY42765.1 - 3.9e-10 39.6 0.2 5.9e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CBY42765.1 - 4.3e-07 29.7 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBY42765.1 - 1.7e-05 24.3 0.8 7.8e-05 22.1 0.8 2.1 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 CBY42765.1 - 0.0035 17.9 0.0 0.0069 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 CBY42765.1 - 0.073 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DUF3173 PF11372.8 CBY42765.1 - 0.096 12.6 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3173) Pkinase PF00069.25 CBY42766.1 - 2.7e-47 161.4 0.0 2.9e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42766.1 - 2.7e-17 62.9 0.0 3.5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY42766.1 - 3.3e-05 23.3 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY42766.1 - 0.0018 17.3 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY42766.1 - 0.0021 18.0 0.1 0.0031 17.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBY42766.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ldh_1_N PF00056.23 CBY42768.1 - 5.3e-40 136.8 1.3 6.4e-40 136.5 1.3 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBY42768.1 - 4.5e-06 25.9 0.0 8.1e-06 25.0 0.0 1.4 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 CBY42768.1 - 0.00049 19.4 0.8 0.036 13.4 0.7 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 CBY42768.1 - 0.0052 16.9 0.8 0.023 14.8 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 CBY42768.1 - 0.017 15.0 0.9 0.033 14.1 0.9 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 CBY42768.1 - 0.033 13.7 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CBY42768.1 - 0.044 14.0 0.4 0.095 13.0 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 CBY42768.1 - 0.053 14.0 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4574 PF15141.6 CBY42768.1 - 0.16 11.9 0.3 1.3 9.0 0.1 2.2 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PROCT PF08084.11 CBY42770.1 - 5.8e-54 181.2 0.0 1.2e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CBY42770.1 - 5.4e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sushi PF00084.20 CBY42773.1 - 0.011 16.3 31.7 0.027 15.1 0.6 6.1 5 0 0 5 5 5 0 Sushi repeat (SCR repeat) Peptidase_C24 PF03510.14 CBY42773.1 - 0.011 16.2 0.3 0.28 11.7 0.0 2.8 3 0 0 3 3 3 0 2C endopeptidase (C24) cysteine protease family LSM PF01423.22 CBY42774.1 - 3.4e-16 58.7 0.0 4.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.11 CBY42774.1 - 0.00074 20.2 5.7 0.001 19.7 5.7 1.3 1 0 0 1 1 1 1 Glycine rich protein family SM-ATX PF14438.6 CBY42774.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain BRCT_3 PF18428.1 CBY42775.1 - 0.0022 18.0 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CBY42775.1 - 0.044 13.7 0.3 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DEAD PF00270.29 CBY42776.1 - 1e-46 158.9 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBY42776.1 - 8.9e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBY42776.1 - 0.0013 19.1 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 CBY42776.1 - 0.0078 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SecA_DEAD PF07517.14 CBY42776.1 - 0.031 13.6 0.0 0.072 12.4 0.0 1.5 1 1 0 1 1 1 0 SecA DEAD-like domain Kelch_1 PF01344.25 CBY42777.1 - 1.5e-72 239.0 11.0 1.4e-15 56.6 0.2 5.1 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 CBY42777.1 - 7.6e-40 133.9 1.8 8.1e-09 35.5 0.0 5.1 1 1 4 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CBY42777.1 - 4.7e-30 102.4 4.3 2e-06 27.6 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CBY42777.1 - 3.2e-25 87.9 0.3 0.00032 20.6 0.0 5.1 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY42777.1 - 5.1e-23 80.8 2.9 3.4e-07 30.4 0.0 5.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY42777.1 - 1.4e-10 40.9 2.3 0.31 11.1 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Glyoxal_oxid_N PF07250.11 CBY42777.1 - 0.17 11.1 1.7 2.7 7.1 0.2 2.2 1 1 1 2 2 2 0 Glyoxal oxidase N-terminus GTP_EFTU PF00009.27 CBY42778.1 - 1.1e-27 96.8 0.2 1.6e-27 96.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY42778.1 - 1.4e-05 25.1 0.2 0.00041 20.4 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBY42778.1 - 6.8e-05 22.6 1.0 0.031 14.0 0.1 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CBY42778.1 - 0.00076 19.4 0.2 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CBY42778.1 - 0.0075 16.3 0.5 0.067 13.2 0.5 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 CBY42778.1 - 0.0097 15.9 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MDD_C PF18376.1 CBY42780.1 - 0.058 13.1 0.1 0.059 13.1 0.1 1.2 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain PRO8NT PF08082.11 CBY42780.1 - 0.11 12.4 2.4 0.11 12.4 2.4 1.0 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain APH PF01636.23 CBY42781.1 - 2.1e-08 34.4 0.0 5.9e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CBY42781.1 - 0.019 13.9 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 CBY42781.1 - 0.032 13.6 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase NAC PF01849.18 CBY42782.1 - 0.094 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 NAC domain Peptidase_M14 PF00246.24 CBY42783.1 - 4.3e-56 190.8 2.0 3.4e-47 161.6 1.6 2.1 2 0 0 2 2 2 2 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY42783.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide TUDOR PF00567.24 CBY42784.1 - 7.2e-10 39.0 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Phosducin PF02114.16 CBY42785.1 - 2.9e-13 49.4 0.1 6.4e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 Phosducin Folliculin PF11704.8 CBY42786.1 - 0.065 13.1 0.7 0.1 12.5 0.2 1.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Gp_dh_C PF02800.20 CBY42791.1 - 1.1e-59 200.6 0.5 1.4e-59 200.2 0.5 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBY42791.1 - 8.9e-05 22.8 0.1 0.00031 21.0 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ACT_4 PF13291.6 CBY42791.1 - 0.064 13.8 0.1 0.23 12.1 0.0 2.0 2 0 0 2 2 2 0 ACT domain CCDC32 PF14989.6 CBY42792.1 - 0.04 13.9 0.2 0.053 13.5 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 DZF PF07528.14 CBY42793.1 - 5.4e-47 160.5 0.0 2.4e-46 158.4 0.0 2.0 1 1 0 1 1 1 1 DZF domain zf-C2H2_jaz PF12171.8 CBY42793.1 - 8.6e-06 25.9 3.0 1.8e-05 24.9 3.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBY42793.1 - 1.2e-05 25.5 0.7 2.3e-05 24.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type dsrm PF00035.26 CBY42793.1 - 0.052 14.3 0.0 0.15 12.7 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Rhomboid_N PF12122.8 CBY42793.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Dicer_dimer PF03368.14 CBY42793.1 - 0.14 12.3 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Dicer dimerisation domain AC_N PF16214.5 CBY42794.1 - 2.1 7.4 5.1 2.6 7.1 5.1 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Exo70 PF03081.15 CBY42795.1 - 8.4e-57 192.9 0.3 1e-56 192.7 0.3 1.0 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CcmH PF03918.14 CBY42796.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PhyH PF05721.13 CBY42797.1 - 8.8e-12 45.7 0.1 1e-11 45.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PK PF00224.21 CBY42797.1 - 0.061 12.2 0.0 0.066 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain cNMP_binding PF00027.29 CBY42799.1 - 1.3e-30 105.3 0.1 1.3e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Patatin PF01734.22 CBY42799.1 - 3.9e-11 43.5 1.8 4.3e-11 43.4 0.3 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase Thioredoxin PF00085.20 CBY42802.1 - 9.7e-08 31.9 0.7 1.2e-07 31.7 0.7 1.1 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 CBY42802.1 - 0.007 16.2 0.0 0.0084 15.9 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 CBY42802.1 - 0.032 14.6 0.1 0.044 14.1 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like Med14 PF08638.11 CBY42802.1 - 0.092 12.1 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 tRNA-synt_2d PF01409.20 CBY42803.1 - 1.3e-53 182.0 0.0 1.4e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 CBY42803.1 - 1e-07 31.7 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CBY42803.1 - 0.0018 17.4 0.0 0.005 16.0 0.0 1.7 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CBY42803.1 - 0.016 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) WW PF00397.26 CBY42804.1 - 2.2e-06 27.6 4.1 4.5e-06 26.7 4.1 1.6 1 0 0 1 1 1 1 WW domain CDC45 PF02724.14 CBY42804.1 - 6.9 4.8 7.5 8.7 4.5 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Arfaptin PF06456.13 CBY42806.1 - 5.8e-46 156.9 10.5 8.6e-46 156.4 10.5 1.2 1 0 0 1 1 1 1 Arfaptin-like domain COOH-NH2_lig PF14395.6 CBY42806.1 - 0.43 9.8 2.7 0.35 10.1 0.1 2.1 3 0 0 3 3 3 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Occludin_ELL PF07303.13 CBY42806.1 - 0.59 10.9 4.4 2.7 8.8 0.1 2.7 2 0 0 2 2 2 0 Occludin homology domain APG6_N PF17675.1 CBY42806.1 - 2.4 8.7 8.8 0.98 9.9 3.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Ammonium_transp PF00909.21 CBY42807.1 - 4.9e-20 71.6 2.0 6e-20 71.3 2.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family HMGL-like PF00682.19 CBY42807.1 - 0.0038 16.8 2.8 0.0049 16.5 2.8 1.1 1 0 0 1 1 1 1 HMGL-like Phage_holin_5_2 PF16079.5 CBY42807.1 - 0.016 15.5 2.5 0.83 10.0 0.1 2.2 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V zf-H2C2_2 PF13465.6 CBY42809.1 - 3.2e-18 65.2 18.1 5.4e-09 36.1 0.8 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY42809.1 - 4e-16 58.5 19.9 1.9e-05 24.9 1.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CBY42809.1 - 1e-12 47.5 13.3 8.9e-09 35.0 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CBY42809.1 - 4.1e-12 45.9 16.6 0.00046 20.8 1.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CBY42809.1 - 3.4e-07 30.4 14.6 0.019 15.3 1.0 3.6 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CBY42809.1 - 3.9e-07 30.8 3.6 3.9e-07 30.8 3.6 2.0 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 CBY42809.1 - 0.001 19.3 7.7 0.16 12.3 5.0 3.2 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CBY42809.1 - 0.002 17.8 11.1 0.0097 15.6 1.0 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CBY42809.1 - 0.0021 18.3 10.7 2.6 8.4 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding BolA PF01722.18 CBY42809.1 - 0.0043 17.3 0.6 0.99 9.7 0.2 2.5 1 1 1 2 2 2 1 BolA-like protein GAGA PF09237.11 CBY42809.1 - 0.015 15.1 3.4 1.4 8.7 0.0 3.3 1 1 2 3 3 3 0 GAGA factor zf-C2H2_6 PF13912.6 CBY42809.1 - 0.028 14.4 1.2 0.028 14.4 1.2 3.8 4 1 0 4 4 2 0 C2H2-type zinc finger Lzipper-MIP1 PF14389.6 CBY42809.1 - 0.053 13.8 2.1 0.085 13.2 0.6 2.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 zf-BED PF02892.15 CBY42809.1 - 0.11 12.6 18.5 0.13 12.3 1.7 3.1 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 CBY42809.1 - 0.12 12.8 16.6 2.3 8.6 1.3 3.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 CBY42809.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.2 1 1 2 3 3 3 0 Zinc-finger OrsD PF12013.8 CBY42809.1 - 0.64 10.5 14.3 2.7 8.5 0.3 3.6 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF629 PF04780.12 CBY42809.1 - 0.83 8.1 7.6 1.9 6.9 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zf_RING PF16744.5 CBY42809.1 - 0.89 9.7 7.2 4.4 7.5 0.1 2.9 2 1 1 3 3 3 0 KIAA1045 RING finger Macoilin PF09726.9 CBY42809.1 - 1.3 7.5 12.8 1.5 7.3 12.8 1.0 1 0 0 1 1 1 0 Macoilin family zf_C2H2_ZHX PF18387.1 CBY42809.1 - 1.5 8.5 10.0 0.54 9.9 0.6 3.0 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-AN1 PF01428.16 CBY42809.1 - 1.6 8.9 7.4 14 6.0 0.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger Cytochrom_c3_2 PF14537.6 CBY42809.1 - 2.6 8.6 12.7 0.99 9.9 9.6 1.9 2 0 0 2 2 2 0 Cytochrome c3 TRAF6_Z2 PF18048.1 CBY42809.1 - 8.5 6.6 8.8 27 5.0 0.2 3.5 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Porphobil_deam PF01379.20 CBY42810.1 - 3.4e-71 239.0 1.5 4.5e-71 238.6 1.5 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CBY42810.1 - 6.1e-17 61.8 0.3 8.8e-16 58.0 0.0 2.8 3 0 0 3 3 3 1 Porphobilinogen deaminase, C-terminal domain zf-C2H2 PF00096.26 CBY42812.1 - 1.4e-08 34.7 18.2 4.1e-05 23.8 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY42812.1 - 6.7e-08 32.6 2.9 6.7e-08 32.6 2.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY42812.1 - 0.00015 22.3 18.3 0.064 14.1 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY42812.1 - 0.0057 16.4 7.6 0.12 12.1 3.9 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type DUF3072 PF11272.8 CBY42812.1 - 0.072 13.0 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) zf-C2H2_jaz PF12171.8 CBY42812.1 - 0.11 12.8 1.0 0.11 12.8 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Polysacc_synt_4 PF04669.13 CBY42816.1 - 2.4e-08 33.7 0.1 0.00025 20.7 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.9 CBY42816.1 - 0.0015 18.8 0.1 0.0025 18.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Polysacc_synt_4 PF04669.13 CBY42817.1 - 2.5e-07 30.4 0.0 0.00049 19.7 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis DAGK_cat PF00781.24 CBY42818.1 - 1.5e-25 89.3 0.1 2.4e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAS_6 PF08348.11 CBY42818.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 YheO-like PAS domain ShK PF01549.24 CBY42819.1 - 2e-12 47.4 62.9 0.0015 19.0 5.7 5.7 5 1 0 5 5 5 5 ShK domain-like SOG2 PF10428.9 CBY42819.1 - 1.1 8.4 15.2 2.1 7.5 15.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_carr PF00153.27 CBY42821.1 - 7.8e-10 38.5 0.0 7.8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein UCR_Fe-S_N PF10399.9 CBY42821.1 - 2.1 7.7 4.2 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Kinesin PF00225.23 CBY42822.1 - 8.9e-65 218.8 0.3 1.3e-64 218.3 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 CBY42822.1 - 2.6e-43 148.3 9.1 1.1e-33 116.8 0.2 3.1 2 1 1 3 3 3 2 Kinesin-associated FHA PF00498.26 CBY42822.1 - 1.6e-05 25.1 0.0 0.0002 21.6 0.0 2.6 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 CBY42822.1 - 0.00059 20.1 0.0 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain HAD_2 PF13419.6 CBY42822.1 - 0.2 11.7 1.1 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CPSF100_C PF13299.6 CBY42824.1 - 8.8e-29 100.9 1.0 8.1e-27 94.5 0.0 2.9 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 CBY42824.1 - 7.7e-12 45.0 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Paf67 PF10255.9 CBY42826.1 - 4.2e-35 121.5 0.0 4.6e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Kelch_5 PF13854.6 CBY42828.1 - 3.6e-16 58.8 0.0 6e-06 26.1 0.0 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 CBY42828.1 - 2e-15 56.5 0.7 0.028 14.4 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY42828.1 - 7.4e-13 48.4 0.9 0.019 15.2 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBY42828.1 - 1.1e-07 31.9 0.0 0.18 12.1 0.0 5.5 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CBY42828.1 - 0.00046 19.7 0.0 0.24 11.0 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY42829.1 - 4.5e-08 32.7 0.1 1.4e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 CBY42829.1 - 1.3e-07 31.1 0.1 2.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 CBY42829.1 - 3.3e-07 30.3 0.0 1.9e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 CBY42829.1 - 9.2e-07 28.7 0.0 0.00019 21.4 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 CBY42829.1 - 1.2e-06 28.5 0.6 2.3e-05 24.3 0.1 2.6 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY42829.1 - 1.7e-05 25.0 0.0 0.0012 19.1 0.1 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain F-box-like PF12937.7 CBY42829.1 - 0.00012 21.9 0.1 0.00035 20.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CBY42829.1 - 0.00056 19.7 0.0 0.0019 18.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CBY42829.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box F-box_5 PF18511.1 CBY42829.1 - 0.064 12.8 0.1 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 F-box Pou PF00157.17 CBY42831.1 - 2e-37 127.0 0.1 8.4e-37 125.0 0.0 2.2 3 0 0 3 3 3 1 Pou domain - N-terminal to homeobox domain Homeodomain PF00046.29 CBY42831.1 - 1.3e-12 47.4 1.0 2.7e-12 46.3 0.5 1.9 2 0 0 2 2 2 1 Homeodomain Mfa1 PF17445.2 CBY42831.1 - 2 8.5 9.6 0.072 13.1 2.3 2.5 2 0 0 2 2 2 0 Mating factor A1 RNase_T PF00929.24 CBY42833.1 - 3.9e-13 50.3 0.0 8.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease NT5C PF06941.12 CBY42833.1 - 0.066 13.1 0.4 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PCI PF01399.27 CBY42834.1 - 3.4e-09 37.2 2.7 5.2e-09 36.5 0.4 2.3 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 CBY42834.1 - 0.0045 16.7 0.5 0.011 15.5 0.4 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 CBY42834.1 - 0.053 14.0 0.1 0.63 10.6 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat RGS-like PF09128.11 CBY42835.1 - 0.53 10.0 6.3 0.83 9.3 6.3 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain CHASE3 PF05227.13 CBY42835.1 - 1.1 9.2 10.7 1.1 9.1 9.3 1.8 1 1 1 2 2 2 0 CHASE3 domain Histone_H2A_C PF16211.5 CBY42836.1 - 2.1e-19 68.9 1.0 4.3e-19 68.0 1.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBY42836.1 - 2.5e-16 60.2 0.0 3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY42836.1 - 0.0014 18.9 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_6 PF13405.6 CBY42837.1 - 1.5e-06 27.6 0.1 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBY42837.1 - 4.3e-05 22.8 0.2 0.00014 21.1 0.0 2.0 2 0 0 2 2 2 1 EF hand PH_12 PF16457.5 CBY42837.1 - 6.5e-05 23.5 0.1 0.0001 22.9 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY42837.1 - 7.8e-05 23.1 0.6 0.00027 21.4 0.3 1.8 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 CBY42837.1 - 0.00028 21.3 0.0 0.0011 19.3 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY42837.1 - 0.0017 17.8 0.1 0.0017 17.8 0.1 2.0 3 0 0 3 3 3 1 EF hand EF-hand_10 PF14788.6 CBY42837.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 EF hand Aldo_ket_red PF00248.21 CBY42838.1 - 6.3e-36 124.1 0.0 7.4e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Xpo1 PF08389.12 CBY42840.1 - 3.4e-06 27.2 2.8 6.2e-06 26.3 1.8 2.0 2 0 0 2 2 2 1 Exportin 1-like protein fn3 PF00041.21 CBY42841.1 - 5.7e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III domain DUF4448 PF14610.6 CBY42842.1 - 0.0052 16.6 0.0 0.0053 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 CBY42842.1 - 0.0059 16.5 0.1 0.0067 16.3 0.1 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.8 CBY42842.1 - 0.019 14.9 0.9 0.026 14.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Prominin PF05478.11 CBY42842.1 - 0.022 12.7 0.0 0.024 12.6 0.0 1.0 1 0 0 1 1 1 0 Prominin Orf78 PF06024.12 CBY42842.1 - 0.025 14.9 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) RAMP PF04901.13 CBY42842.1 - 0.032 14.2 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Receptor activity modifying family CD34_antigen PF06365.12 CBY42842.1 - 0.059 12.9 0.0 0.065 12.8 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Insulin_TMD PF17870.1 CBY42842.1 - 0.14 12.2 3.1 0.21 11.7 3.1 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment HA2 PF04408.23 CBY42845.1 - 1.2e-23 83.4 0.1 2.1e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY42845.1 - 1.8e-19 69.9 0.0 3.9e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBY42845.1 - 2.4e-05 24.6 0.1 0.00012 22.4 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_98M PF08306.11 CBY42845.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 Abhydrolase_2 PF02230.16 CBY42847.1 - 5.4e-59 199.6 0.0 6.1e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBY42847.1 - 2.2e-11 43.5 0.0 7.9e-05 22.0 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CBY42847.1 - 1.5e-08 34.6 0.0 7.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CBY42847.1 - 3.8e-08 33.1 0.0 5.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CBY42847.1 - 3.3e-07 30.0 0.1 0.033 13.7 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family Esterase PF00756.20 CBY42847.1 - 4.2e-06 26.6 0.0 6.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CBY42847.1 - 2.5e-05 24.1 0.6 0.031 13.9 0.3 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CBY42847.1 - 0.00018 21.5 0.0 0.053 13.4 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBY42847.1 - 0.00023 21.9 0.0 0.00041 21.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 CBY42847.1 - 0.00028 19.5 0.0 0.0004 19.0 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 CBY42847.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CBY42847.1 - 0.0027 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.22 CBY42847.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase AXE1 PF05448.12 CBY42847.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 CBY42847.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Palm_thioest PF02089.15 CBY42847.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase BAAT_C PF08840.11 CBY42847.1 - 0.12 12.3 0.1 4.1 7.3 0.1 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 CBY42847.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein Diphthamide_syn PF01866.17 CBY42848.1 - 4.5e-27 95.3 0.0 3e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein CPSF_A PF03178.15 CBY42850.1 - 1.4e-39 136.3 0.0 1.6e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Helicase_C PF00271.31 CBY42851.1 - 6.3e-22 78.0 0.0 6.3e-22 78.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CBY42851.1 - 4.1e-12 46.2 7.8 5e-12 45.9 4.0 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ImmE5 PF11480.8 CBY42851.1 - 0.026 15.0 3.5 0.44 11.1 0.1 3.2 2 1 1 3 3 3 0 Colicin-E5 Imm protein TCTP PF00838.17 CBY42851.1 - 2 8.7 8.0 0.13 12.5 0.7 2.5 3 0 0 3 3 3 0 Translationally controlled tumour protein Fib_alpha PF08702.10 CBY42852.1 - 0.00095 19.4 3.5 0.0012 19.0 3.5 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CSN5_C PF18323.1 CBY42852.1 - 0.0043 17.9 0.3 0.0043 17.9 0.3 1.6 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain DUF2408 PF10303.9 CBY42852.1 - 0.0068 17.0 3.1 0.0072 16.9 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) RRF_GI PF12614.8 CBY42852.1 - 0.015 15.5 1.0 0.019 15.1 1.0 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Tho2 PF11262.8 CBY42852.1 - 0.057 12.6 3.1 0.069 12.3 3.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Lectin_N PF03954.14 CBY42852.1 - 0.058 13.2 0.3 0.073 12.8 0.3 1.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 CBY42852.1 - 0.062 12.5 1.7 0.068 12.4 1.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.6 CBY42852.1 - 0.99 9.4 7.3 1.2 9.2 6.7 1.5 1 1 0 1 1 1 0 FlxA-like protein HA2 PF04408.23 CBY42854.1 - 6.3e-17 61.8 2.1 6e-16 58.7 2.1 2.4 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBY42854.1 - 5e-10 39.6 0.0 8.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF2407_C PF13373.6 CBY42854.1 - 0.84 9.8 3.1 1.3 9.2 1.9 1.9 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF572 PF04502.13 CBY42854.1 - 0.91 9.1 7.5 1.2 8.7 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bromodomain PF00439.25 CBY42855.1 - 5.7e-15 55.2 0.1 7.9e-15 54.7 0.1 1.1 1 0 0 1 1 1 1 Bromodomain Aldedh PF00171.22 CBY42858.1 - 1e-90 304.5 0.0 1.2e-90 304.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CBY42858.1 - 0.065 13.1 0.5 0.15 11.9 0.5 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RNB PF00773.19 CBY42859.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 RNB domain TK PF00265.18 CBY42860.1 - 2.4e-60 203.4 0.1 2.7e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 CBY42860.1 - 0.0046 16.9 0.0 0.0057 16.6 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF3785 PF12653.7 CBY42860.1 - 0.0067 16.5 0.3 0.021 14.9 0.0 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3785) AAA_14 PF13173.6 CBY42860.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain HNH_5 PF14279.6 CBY42860.1 - 0.016 15.1 0.3 0.027 14.3 0.3 1.4 1 0 0 1 1 1 0 HNH endonuclease DUF2064 PF09837.9 CBY42860.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Ion_trans_2 PF07885.16 CBY42861.1 - 1.2e-15 57.2 0.7 1.5e-15 56.9 0.7 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 CBY42861.1 - 6.6e-15 55.0 0.0 7.8e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein VWA PF00092.28 CBY42862.1 - 2.6e-13 50.6 0.0 3.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.19 CBY42862.1 - 1.3e-09 38.1 25.5 5.1e-06 26.6 6.3 2.4 2 0 0 2 2 2 2 Thrombospondin type 1 domain TSP_1 PF00090.19 CBY42863.1 - 1.3e-40 137.4 108.7 4.2e-11 42.9 6.1 7.9 7 1 1 8 8 8 6 Thrombospondin type 1 domain zf_CCCH_4 PF18345.1 CBY42863.1 - 0.55 10.4 33.3 3.9 7.7 0.8 8.0 7 0 0 7 7 7 0 Zinc finger domain zf-CCCH PF00642.24 CBY42863.1 - 7.8 6.5 37.3 2.4 8.2 0.4 8.2 8 0 0 8 8 8 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.16 CBY42865.1 - 7e-08 31.8 0.1 8.8e-08 31.4 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2157 PF09925.9 CBY42865.1 - 0.13 12.0 1.2 0.3 10.9 0.1 2.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) JmjC PF02373.22 CBY42866.1 - 2.6e-14 53.6 0.0 6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C2H2 PF00096.26 CBY42867.1 - 2e-18 65.7 28.6 0.00072 19.9 2.5 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CBY42867.1 - 6.3e-13 48.5 19.9 1.5e-05 25.2 0.1 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY42867.1 - 4.3e-08 33.3 28.1 0.04 14.8 2.7 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf_ZIC PF18366.1 CBY42867.1 - 1.6e-06 28.1 10.9 4.9e-05 23.3 1.2 4.5 3 1 1 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 CBY42867.1 - 0.00013 22.2 12.0 0.86 10.0 0.9 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CBY42867.1 - 0.00071 20.2 15.8 2.6 8.7 0.3 4.2 2 2 2 4 4 4 3 FOXP coiled-coil domain DUF4729 PF15866.5 CBY42867.1 - 0.0038 16.6 0.2 0.033 13.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4729) zf-met PF12874.7 CBY42867.1 - 0.005 17.2 11.5 6.3 7.3 1.5 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 CBY42867.1 - 0.037 14.7 6.4 0.86 10.3 0.3 3.0 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 CBY42867.1 - 0.039 14.2 9.0 0.54 10.6 4.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 CBY42867.1 - 0.18 11.6 14.8 4.3 7.2 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain IBR PF01485.21 CBY42867.1 - 0.31 11.3 9.8 0.1 12.8 1.8 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_aberr PF17017.5 CBY42867.1 - 4.2 7.5 10.7 3.3 7.8 3.9 2.9 1 1 3 4 4 4 0 Aberrant zinc-finger zf-Di19 PF05605.12 CBY42867.1 - 6 7.3 13.6 5 7.5 0.3 3.7 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Proteasome PF00227.26 CBY42868.1 - 3.2e-33 114.8 0.2 3.6e-33 114.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3834 PF12916.7 CBY42868.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) APG9 PF04109.16 CBY42869.1 - 1.3e-21 77.2 1.9 1.5e-21 77.0 1.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Methyltr_RsmB-F PF01189.17 CBY42870.1 - 2.8e-29 102.2 0.1 9.7e-28 97.2 0.1 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 CBY42870.1 - 3.3e-07 30.9 0.0 0.00033 21.3 0.0 2.6 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CBY42870.1 - 1.8e-06 28.5 0.0 0.03 15.0 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 CBY42870.1 - 3.7e-06 27.2 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CBY42870.1 - 0.00087 19.1 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PUA PF01472.20 CBY42870.1 - 0.0036 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 PUA domain N6_N4_Mtase PF01555.18 CBY42870.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA methylase MGAT2 PF05060.14 CBY42871.1 - 6.7e-97 324.7 0.4 7.8e-97 324.5 0.4 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) GNT-I PF03071.15 CBY42871.1 - 0.023 13.5 0.1 0.94 8.2 0.0 2.1 2 0 0 2 2 2 0 GNT-I family LCM PF04072.14 CBY42872.1 - 1.3e-10 41.6 0.1 2.3e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Ank_5 PF13857.6 CBY42872.1 - 1.4e-08 34.9 0.0 5.9e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBY42872.1 - 2.3e-08 34.4 0.0 0.0003 21.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY42872.1 - 1.1e-06 29.1 0.0 4.1e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY42872.1 - 2.2e-06 27.6 0.0 0.0085 16.5 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CBY42872.1 - 6.1e-05 23.3 0.0 0.00034 20.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat EF-hand_1 PF00036.32 CBY42874.1 - 1.4e-06 27.4 0.0 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY42874.1 - 0.00016 21.3 0.0 0.55 10.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBY42874.1 - 0.00018 20.9 0.1 3 7.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY42874.1 - 0.0083 16.0 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair Astro_capsid_p2 PF16580.5 CBY42874.1 - 0.056 12.9 1.5 0.29 10.5 0.1 2.1 1 1 1 2 2 2 0 C-terminal tail of astrovirus capsid projection or spike EF-hand_4 PF12763.7 CBY42874.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CBY42874.1 - 0.17 12.3 0.0 1.4 9.5 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair NT-C2 PF10358.9 CBY42876.1 - 1.2e-15 57.5 0.4 1.8e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins C2 PF00168.30 CBY42876.1 - 7e-05 23.1 0.2 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain Kringle PF00051.18 CBY42878.1 - 2.7e-13 50.0 4.7 4e-13 49.5 4.7 1.3 1 0 0 1 1 1 1 Kringle domain DEAD PF00270.29 CBY42881.1 - 5.5e-41 140.2 0.2 9e-40 136.3 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY42881.1 - 2.1e-26 92.4 2.4 2.9e-26 92.0 0.6 2.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBY42881.1 - 2.1e-06 27.9 0.0 4.8e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBY42881.1 - 0.016 14.5 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SOSSC PF15925.5 CBY42882.1 - 0.00019 22.7 0.1 0.00022 22.5 0.1 1.1 1 0 0 1 1 1 1 SOSS complex subunit C GCS PF03074.16 CBY42882.1 - 0.027 13.9 0.2 0.029 13.8 0.2 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase PMSR PF01625.21 CBY42882.1 - 0.076 13.2 0.6 0.088 13.0 0.6 1.0 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase YccV-like PF08755.11 CBY42883.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.5 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Zona_pellucida PF00100.23 CBY42884.1 - 1.3e-18 67.7 0.3 1.8e-18 67.3 0.3 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain RrnaAD PF00398.20 CBY42886.1 - 1.7e-61 207.6 0.1 2.2e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBY42886.1 - 9.3e-09 35.9 0.0 2.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY42886.1 - 9.2e-06 26.2 0.0 2.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY42886.1 - 0.00011 22.9 0.0 0.00021 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBY42886.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBY42886.1 - 0.00094 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CBY42886.1 - 0.0031 17.0 0.0 0.0068 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 CBY42886.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 CBY42886.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 CBY42886.1 - 0.0099 15.6 0.0 0.024 14.3 0.0 1.6 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 CBY42886.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CBY42886.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CBY42886.1 - 0.034 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 CBY42886.1 - 0.044 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.12 CBY42886.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.15 CBY42886.1 - 0.047 13.3 0.1 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 CBY42886.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3993 PF13158.6 CBY42886.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) SHIPPO-rpt PF07004.12 CBY42887.1 - 2.1e-17 63.1 29.5 0.00075 20.3 1.6 6.5 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat ECR1_N PF14382.6 CBY42887.1 - 0.013 15.3 0.2 15 5.5 0.0 3.5 3 0 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Galactosyl_T PF01762.21 CBY42888.1 - 0.00083 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase LIN37 PF15306.6 CBY42888.1 - 0.025 14.8 1.8 0.036 14.3 1.8 1.2 1 0 0 1 1 1 0 LIN37 FERM_M PF00373.18 CBY42889.1 - 4e-09 36.9 0.3 8.1e-07 29.5 0.3 2.4 1 1 0 1 1 1 1 FERM central domain FERM_N PF09379.10 CBY42889.1 - 4.5e-07 29.7 0.0 1.6e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 FERM N-terminal domain Noggin PF05806.12 CBY42889.1 - 0.068 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Noggin Hydrolase PF00702.26 CBY42890.1 - 4.5e-05 23.8 0.0 8.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AgrB PF04647.15 CBY42890.1 - 0.017 14.4 0.7 0.035 13.4 0.7 1.4 1 0 0 1 1 1 0 Accessory gene regulator B SHIPPO-rpt PF07004.12 CBY42891.1 - 5.1e-17 61.9 29.0 0.00095 20.0 1.6 6.5 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat EF-hand_1 PF00036.32 CBY42892.1 - 1.5e-27 93.0 8.5 2.2e-06 26.8 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CBY42892.1 - 4.4e-24 82.3 3.7 2.5e-06 26.9 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBY42892.1 - 4.9e-23 81.4 3.9 2.6e-11 43.8 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY42892.1 - 3.2e-20 70.7 7.5 1.3e-05 24.5 0.2 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CBY42892.1 - 8.7e-16 57.5 13.9 0.00017 21.3 1.2 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBY42892.1 - 2.1e-06 27.6 7.5 0.67 9.9 0.1 4.0 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBY42892.1 - 1.7e-05 25.1 0.6 0.004 17.4 0.1 2.9 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBY42892.1 - 0.0036 17.5 7.9 4 7.7 0.2 4.0 2 1 2 4 4 4 3 Dockerin type I domain ETAA1 PF15350.6 CBY42895.1 - 0.093 11.0 0.8 0.11 10.8 0.8 1.0 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue EF-hand_1 PF00036.32 CBY42897.1 - 7.9e-14 50.1 0.0 0.00011 21.5 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBY42897.1 - 6.7e-12 44.3 0.9 1.1e-05 25.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY42897.1 - 1.4e-11 44.7 0.5 3.2e-10 40.3 0.1 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CBY42897.1 - 1.6e-08 33.7 0.4 3.1e-05 23.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY42897.1 - 4.2e-06 26.5 0.1 1.4e-05 24.9 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 CBY42897.1 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 CBY42897.1 - 0.013 16.3 0.0 0.024 15.5 0.0 1.4 1 1 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 CBY42897.1 - 0.069 13.5 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Nsp1_C PF05064.13 CBY42899.1 - 9.2e-19 67.4 2.8 9.2e-19 67.4 2.8 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Laminin_I PF06008.14 CBY42899.1 - 0.00026 20.8 5.0 0.00026 20.8 5.0 1.8 1 1 1 2 2 2 1 Laminin Domain I Fib_alpha PF08702.10 CBY42899.1 - 0.00057 20.1 1.4 0.0013 18.9 0.9 1.8 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family SOGA PF11365.8 CBY42899.1 - 0.0077 17.3 3.2 2.2 9.5 1.5 2.4 2 1 0 2 2 2 1 Protein SOGA GAS PF13851.6 CBY42899.1 - 0.026 13.9 7.8 0.08 12.3 7.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 CBY42899.1 - 0.031 14.6 1.0 0.031 14.6 1.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) SYCE1 PF15233.6 CBY42899.1 - 0.04 14.0 5.9 0.073 13.1 5.9 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 ALIX_LYPXL_bnd PF13949.6 CBY42899.1 - 0.05 12.9 7.1 0.54 9.5 3.3 2.0 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DUF2746 PF10874.8 CBY42899.1 - 0.062 13.7 0.3 0.16 12.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) Baculo_p24 PF05073.12 CBY42899.1 - 0.08 12.7 0.9 0.13 12.0 0.9 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Snapin_Pallidin PF14712.6 CBY42899.1 - 0.2 12.1 7.9 0.18 12.2 3.2 2.7 2 1 1 3 3 3 0 Snapin/Pallidin Laminin_II PF06009.12 CBY42899.1 - 0.21 11.6 7.7 0.99 9.4 3.1 2.4 1 1 1 2 2 2 0 Laminin Domain II Med30 PF11315.8 CBY42899.1 - 0.22 11.7 4.7 0.11 12.7 2.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 30 CdvA PF18822.1 CBY42899.1 - 0.29 11.0 4.7 4.5 7.1 0.2 2.9 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DUF948 PF06103.11 CBY42899.1 - 0.41 10.9 6.2 8.5 6.7 2.2 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HalX PF08663.10 CBY42899.1 - 0.59 10.5 5.5 13 6.2 0.1 3.3 4 0 0 4 4 4 0 HalX domain DUF1664 PF07889.12 CBY42899.1 - 0.78 9.8 7.5 6.6 6.8 1.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 CBY42899.1 - 0.86 10.0 7.4 0.47 10.8 3.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rx_N PF18052.1 CBY42899.1 - 0.87 9.9 5.8 2.7 8.3 0.1 3.0 2 1 0 2 2 2 0 Rx N-terminal domain Lipoprotein_20 PF13942.6 CBY42899.1 - 1 9.3 7.2 1.8 8.4 3.1 2.7 1 1 1 3 3 3 0 YfhG lipoprotein Spc7 PF08317.11 CBY42899.1 - 1.1 8.1 9.5 0.89 8.4 5.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CBY42899.1 - 1.1 9.5 10.0 1.4 9.2 1.4 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CBY42899.1 - 1.2 9.6 12.6 0.23 12.0 5.1 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 CBY42899.1 - 1.4 9.4 4.0 15 6.1 0.8 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 CBY42899.1 - 1.6 7.9 3.7 3.3 6.9 3.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein Sec34 PF04136.15 CBY42899.1 - 1.7 8.6 5.5 3.1 7.7 2.1 2.2 1 1 0 2 2 2 0 Sec34-like family YabA PF06156.13 CBY42899.1 - 4.2 8.1 6.0 3.3 8.4 2.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 CBY42899.1 - 4.4 7.1 12.9 2.9 7.7 5.8 3.4 2 1 2 4 4 4 0 Septum formation initiator Spc24 PF08286.11 CBY42899.1 - 5 7.4 9.4 1.4e+02 2.7 9.4 2.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 CBY42899.1 - 8.4 6.9 7.8 2e+02 2.5 7.8 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.16 CBY42901.1 - 3.4e-37 128.2 23.4 4.1e-37 127.9 23.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY42901.1 - 2e-08 33.5 24.8 1.8e-06 27.1 24.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DHHC PF01529.20 CBY42901.1 - 1.2 9.2 10.6 4.2 7.5 1.2 3.2 3 1 0 3 3 3 0 DHHC palmitoyltransferase Gar1 PF04410.14 CBY42904.1 - 1.1e-35 122.7 0.0 1.4e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Pkinase PF00069.25 CBY42905.1 - 2e-11 43.8 0.1 4.1e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42905.1 - 2.2e-07 30.4 0.0 2.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CR6_interact PF10147.9 CBY42905.1 - 0.026 14.3 0.6 0.026 14.3 0.6 1.6 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1403 PF07183.11 CBY42905.1 - 0.067 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Phospholip_A2_1 PF00068.19 CBY42907.1 - 3.1e-14 53.4 11.7 3.1e-14 53.4 11.7 2.5 2 2 0 2 2 2 1 Phospholipase A2 Sulfotransfer_4 PF17784.1 CBY42908.1 - 2.9e-21 76.3 0.0 3.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Pkinase PF00069.25 CBY42909.1 - 1.7e-38 132.5 0.0 2.2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42909.1 - 9e-30 103.8 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY42909.1 - 0.0028 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CBY42909.1 - 0.003 16.7 0.1 0.0047 16.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CBY42909.1 - 0.018 14.0 0.0 0.018 14.0 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain LPP PF04728.13 CBY42910.1 - 0.039 14.3 16.7 0.1 13.0 3.8 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FUSC PF04632.12 CBY42910.1 - 3.7 6.0 6.4 0.96 7.9 1.9 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family IF4E PF01652.18 CBY42912.1 - 5.2e-44 149.8 0.2 6.2e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NAD_kinase PF01513.21 CBY42915.1 - 5.5e-65 219.4 0.0 6.8e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CBY42915.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain LEF-8 PF04941.12 CBY42917.1 - 1.2 7.3 3.4 1.6 6.9 3.4 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) HD_4 PF13328.6 CBY42918.1 - 6e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 HD domain HD PF01966.22 CBY42918.1 - 1.2e-05 25.5 0.3 6.6e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 HD domain Vps39_2 PF10367.9 CBY42918.1 - 0.074 13.5 0.3 6.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Carn_acyltransf PF00755.20 CBY42920.1 - 4.2e-71 240.3 1.1 4.7e-71 240.2 1.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CHGN PF05679.16 CBY42922.1 - 1.6e-20 73.4 0.9 1.8e-20 73.3 0.9 1.0 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase Clat_adaptor_s PF01217.20 CBY42924.1 - 1.5e-46 157.9 1.2 1.8e-46 157.6 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 CBY42924.1 - 0.015 16.0 0.5 0.11 13.2 0.5 2.2 1 1 0 1 1 1 0 Homeobox-cysteine loop-homeobox MFS_1 PF07690.16 CBY42925.1 - 1.8e-10 40.3 25.6 1.3e-07 30.9 9.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Cullin PF00888.22 CBY42926.1 - 6.2e-84 282.8 2.9 9.2e-84 282.2 2.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY42926.1 - 3.5e-13 49.4 0.1 9e-13 48.1 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain USP8_interact PF08941.10 CBY42928.1 - 1.2e-68 230.5 1.1 1.7e-68 229.9 1.1 1.2 1 0 0 1 1 1 1 USP8 interacting zf-C3HC4_2 PF13923.6 CBY42928.1 - 2.5e-10 40.0 6.3 2.5e-10 40.0 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY42928.1 - 4e-08 33.5 6.4 4e-08 33.5 6.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBY42928.1 - 1.1e-07 31.6 6.8 1.1e-07 31.6 6.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY42928.1 - 2.4e-07 30.5 3.9 2.4e-07 30.5 3.9 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY42928.1 - 1.6e-06 28.1 7.1 1.6e-06 28.1 7.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBY42928.1 - 2.7e-06 27.6 9.0 2.7e-06 27.6 9.0 2.9 3 1 1 4 4 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBY42928.1 - 7.8e-05 22.6 5.1 7.8e-05 22.6 5.1 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CBY42928.1 - 0.0001 22.1 0.9 0.00037 20.3 0.6 2.1 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY42928.1 - 0.00038 20.2 6.5 0.0083 16.0 7.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY42928.1 - 0.00041 20.4 6.5 0.00041 20.4 6.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CBY42928.1 - 0.00081 19.4 3.8 0.0032 17.5 3.2 2.4 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.16 CBY42928.1 - 0.00093 19.2 5.3 0.0017 18.4 4.0 1.9 2 0 0 2 2 2 1 Seven in absentia protein family U-box PF04564.15 CBY42928.1 - 0.002 18.2 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 CBY42928.1 - 0.0028 17.4 1.7 0.0072 16.1 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 CBY42928.1 - 0.0034 17.0 4.3 0.0034 17.0 4.3 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type TMF_DNA_bd PF12329.8 CBY42928.1 - 0.061 13.3 1.2 0.061 13.3 1.2 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-TRAF PF02176.18 CBY42928.1 - 0.2 12.4 12.2 2.2 9.0 4.4 3.0 1 1 1 2 2 2 0 TRAF-type zinc finger Trm112p PF03966.16 CBY42928.1 - 0.56 10.8 4.1 22 5.7 0.2 3.5 2 2 1 3 3 3 0 Trm112p-like protein zf-RING_4 PF14570.6 CBY42928.1 - 1 9.2 14.8 1.6 8.6 8.3 3.0 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 CBY42928.1 - 7.7 6.8 17.3 4.3 7.6 7.4 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain MAM PF00629.23 CBY42933.1 - 1.8e-09 37.7 0.2 2.1e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu Tat PF00539.18 CBY42936.1 - 0.51 10.5 3.3 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) DUF3617 PF12276.8 CBY42937.1 - 0.032 14.6 0.3 0.055 13.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) HBS1_N PF08938.10 CBY42937.1 - 0.055 13.8 4.5 1.6 9.1 0.0 3.2 2 2 2 4 4 4 0 HBS1 N-terminus Peptidase_S41_N PF11918.8 CBY42937.1 - 0.096 12.9 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Sulfotransfer_3 PF13469.6 CBY42939.1 - 5.3e-05 23.7 0.0 9.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 CBY42939.1 - 0.0032 17.0 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Gram_pos_anchor PF00746.21 CBY42940.1 - 0.0064 16.4 0.2 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 LPXTG cell wall anchor motif Syndecan PF01034.20 CBY42940.1 - 0.053 13.4 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain LapA_dom PF06305.11 CBY42941.1 - 0.31 10.9 3.3 0.55 10.1 3.3 1.4 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Filament PF00038.21 CBY42943.1 - 3.8e-45 154.8 16.7 4.8e-45 154.5 16.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 CBY42943.1 - 0.00061 18.8 11.6 0.00079 18.4 11.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CBY42943.1 - 0.0013 18.8 12.6 0.04 14.0 5.4 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 CBY42943.1 - 0.018 14.4 13.1 0.025 14.0 13.1 1.3 1 0 0 1 1 1 0 Rabaptin-like protein DUF5082 PF16888.5 CBY42943.1 - 0.045 14.0 10.8 0.087 13.1 9.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF775 PF05603.12 CBY42943.1 - 0.052 13.1 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) YtxH PF12732.7 CBY42943.1 - 0.25 11.9 5.5 0.32 11.5 1.4 3.0 1 1 1 2 2 2 0 YtxH-like protein DHR10 PF18595.1 CBY42943.1 - 0.29 11.2 16.9 0.2 11.7 7.7 2.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 CBY42943.1 - 0.76 9.8 18.7 6.6 6.8 18.7 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 CBY42943.1 - 0.83 10.3 11.3 0.64 10.6 2.2 2.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Laminin_II PF06009.12 CBY42943.1 - 0.93 9.5 9.3 1.1 9.3 4.8 2.2 1 1 1 2 2 2 0 Laminin Domain II T6PP_N PF18572.1 CBY42943.1 - 1.3 8.9 10.0 1.2e+02 2.6 10.0 2.7 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain V_ATPase_I PF01496.19 CBY42943.1 - 1.4 6.8 5.8 1.9 6.3 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 CBY42943.1 - 1.8 8.6 12.1 49 4.0 9.3 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 CBY42943.1 - 2.2 8.5 17.6 1.8 8.8 3.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Lzipper-MIP1 PF14389.6 CBY42943.1 - 2.9 8.2 10.1 2 8.8 0.8 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Nup88 PF10168.9 CBY42943.1 - 3.2 5.5 11.2 5 4.8 11.0 1.3 1 1 0 1 1 1 0 Nuclear pore component DUF4549 PF15082.6 CBY42943.1 - 3.4 7.5 6.7 5.4 6.8 0.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) COG2 PF06148.11 CBY42943.1 - 3.6 7.7 9.2 1.3 9.1 4.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 CBY42943.1 - 4 7.5 9.6 12 6.0 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 CBY42943.1 - 9.8 5.2 10.6 39 3.2 10.6 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_1 PF00036.32 CBY42944.1 - 2.7e-17 60.9 5.1 6.9e-08 31.5 0.2 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBY42944.1 - 2.6e-14 51.8 7.2 4e-06 26.3 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CBY42944.1 - 8.8e-12 45.3 2.6 0.00029 21.2 1.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY42944.1 - 1.9e-11 42.9 8.8 1.2e-06 27.7 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBY42944.1 - 8e-06 25.6 2.9 0.15 11.9 0.1 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CBY42944.1 - 0.035 14.4 0.2 12 6.4 0.0 3.3 3 1 1 4 4 4 0 EF-hand domain GCV_H PF01597.19 CBY42944.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SPARC_Ca_bdg PF10591.9 CBY42944.1 - 0.074 13.4 0.1 17 5.7 0.0 3.0 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CBY42944.1 - 0.13 12.2 0.5 5.2 7.0 0.1 2.2 1 1 0 2 2 2 0 Caleosin related protein Excalibur PF05901.11 CBY42944.1 - 1.7 9.3 6.3 2.9 8.6 0.1 2.7 3 0 0 3 3 3 0 Excalibur calcium-binding domain FtsJ PF01728.19 CBY42946.1 - 1.6e-13 51.2 0.0 2.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DWNN PF08783.11 CBY42946.1 - 0.1 12.9 0.2 0.52 10.6 0.1 1.9 2 0 0 2 2 2 0 DWNN domain Mito_carr PF00153.27 CBY42947.1 - 0.00022 21.1 0.1 0.00022 21.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein EMP24_GP25L PF01105.24 CBY42948.1 - 1.9e-18 67.1 0.5 2.1e-18 66.9 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Baculo_F PF12259.8 CBY42948.1 - 0.0041 15.7 0.4 0.0048 15.5 0.4 1.0 1 0 0 1 1 1 1 Baculovirus F protein JMY PF15871.5 CBY42948.1 - 0.076 12.3 4.1 0.086 12.1 4.1 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Na_H_antiport_3 PF07399.11 CBY42949.1 - 0.027 13.4 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Putative Na+/H+ antiporter Fz PF01392.22 CBY42951.1 - 0.0069 17.0 0.2 0.0078 16.8 0.2 1.1 1 0 0 1 1 1 1 Fz domain Pkinase PF00069.25 CBY42953.1 - 5.2e-06 26.0 0.0 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42953.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Penicillinase_R PF03965.16 CBY42953.1 - 0.057 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Penicillinase repressor HEAT PF02985.22 CBY42954.1 - 2.5e-19 67.7 5.5 0.019 15.2 0.0 7.6 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.6 CBY42954.1 - 8e-12 45.4 0.1 0.018 15.4 0.2 5.2 2 1 3 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 CBY42954.1 - 0.00012 22.6 0.3 5.2 7.7 0.2 4.5 2 1 3 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CBY42954.1 - 0.0028 17.7 2.7 7.7 6.5 0.0 3.9 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CBY42954.1 - 0.0068 16.0 0.4 0.049 13.2 0.1 2.4 2 1 1 3 3 3 1 CLASP N terminal EBV-NA3 PF05009.12 CBY42954.1 - 0.31 10.5 1.3 0.54 9.8 1.3 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) WRNPLPNID PF15017.6 CBY42954.1 - 1.3 9.9 9.8 0.24 12.3 5.5 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Pkinase PF00069.25 CBY42957.1 - 8.3e-09 35.2 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY42957.1 - 0.00088 18.6 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ALAD PF00490.21 CBY42958.1 - 1.7e-57 195.0 0.0 2.2e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Leu_zip PF15294.6 CBY42959.1 - 2.1 7.8 32.9 2.2 7.7 9.6 2.1 2 0 0 2 2 2 0 Leucine zipper DUF2681 PF10883.8 CBY42959.1 - 2.8 8.4 16.5 7.5 7.0 2.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Fez1 PF06818.15 CBY42959.1 - 6.2 7.2 35.0 0.3 11.5 14.7 2.4 1 1 1 2 2 2 0 Fez1 EF-hand_7 PF13499.6 CBY42961.1 - 7.1e-05 23.2 1.0 0.0001 22.6 1.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY42961.1 - 0.0083 16.0 1.3 0.036 13.9 0.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.7 CBY42961.1 - 0.043 13.8 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CBY42961.1 - 0.37 10.5 3.5 1.2 8.9 0.5 2.5 3 0 0 3 3 3 0 EF hand CAS_CSE1 PF03378.15 CBY42962.1 - 0.021 13.3 0.0 0.036 12.5 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Peptidase_M16_C PF05193.21 CBY42964.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16 inactive domain Transket_pyr PF02779.24 CBY42965.1 - 9.2e-35 119.9 0.0 1.6e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY42965.1 - 3.3e-30 104.5 0.9 7e-30 103.5 0.9 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 CBY42965.1 - 7e-20 71.2 0.2 1.7e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 CBY42965.1 - 9.2e-12 44.5 0.1 1.8e-11 43.6 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CBY42965.1 - 0.01 15.0 0.1 0.33 10.1 0.0 2.2 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase PFOR_II PF17147.4 CBY42965.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II XFP_N PF09364.10 CBY42965.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 XFP N-terminal domain GST_N_3 PF13417.6 CBY42966.1 - 5.1e-11 42.8 0.0 6.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBY42966.1 - 1.2e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY42966.1 - 7.5e-07 29.4 0.0 9.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TRAP_alpha PF03896.16 CBY42967.1 - 1e-31 110.2 6.2 2.3e-31 109.1 6.2 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF3493 PF11998.8 CBY42967.1 - 0.16 12.2 2.0 0.43 10.8 2.0 1.7 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 PRP3 PF08572.10 CBY42968.1 - 0.044 13.5 3.8 0.049 13.4 3.8 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Histone PF00125.24 CBY42969.1 - 1.7e-16 60.8 0.2 2e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY42969.1 - 0.00028 21.1 0.1 0.00047 20.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY42969.1 - 0.098 13.2 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY42969.1 - 0.16 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 CBY42970.1 - 1.2e-15 58.0 0.0 1.6e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBY42970.1 - 5e-15 54.9 0.5 5e-15 54.9 0.5 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CBY42970.1 - 1.3e-06 28.6 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPD52 PF04201.15 CBY42971.1 - 1e-29 103.2 0.3 1.2e-29 103.0 0.3 1.1 1 0 0 1 1 1 1 Tumour protein D52 family WEMBL PF05701.11 CBY42971.1 - 0.028 13.1 0.8 0.033 12.9 0.8 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TMF_TATA_bd PF12325.8 CBY42971.1 - 0.14 12.3 4.1 0.42 10.8 4.5 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PspA_IM30 PF04012.12 CBY42971.1 - 0.33 10.5 5.1 0.56 9.8 5.1 1.5 1 1 0 1 1 1 0 PspA/IM30 family Prefoldin_2 PF01920.20 CBY42971.1 - 0.47 10.4 6.1 0.2 11.6 3.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit ABC_tran_CTD PF16326.5 CBY42971.1 - 1.1 9.6 5.5 18 5.7 0.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Zip PF02535.22 CBY42974.1 - 3.8e-10 39.5 10.1 6e-10 38.9 10.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter PSI_PsaH PF03244.14 CBY42974.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI MFS_1 PF07690.16 CBY42974.1 - 0.21 10.5 7.4 0.36 9.7 7.4 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF4133 PF13571.6 CBY42974.1 - 0.39 11.1 3.5 13 6.2 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4133) Phage_holin_4_2 PF04020.13 CBY42974.1 - 0.77 10.5 9.6 0.95 10.2 9.6 1.1 1 0 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV MerC PF03203.14 CBY42974.1 - 1.3 9.5 7.7 2.3 8.7 7.7 1.5 1 1 0 1 1 1 0 MerC mercury resistance protein ATP-sulfurylase PF01747.17 CBY42975.1 - 0.18 11.3 0.3 0.21 11.1 0.3 1.3 1 1 0 1 1 1 0 ATP-sulfurylase Rhomboid PF01694.22 CBY42976.1 - 4.9e-09 36.4 3.0 4.9e-09 36.4 3.0 1.8 2 0 0 2 2 2 1 Rhomboid family Pox_A28 PF04584.14 CBY42976.1 - 0.009 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A28 family Otopetrin PF03189.13 CBY42976.1 - 0.048 12.5 0.2 0.052 12.4 0.2 1.1 1 0 0 1 1 1 0 Otopetrin DUF4451 PF14616.6 CBY42978.1 - 0.4 10.9 6.6 21 5.3 6.6 3.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) DUF5435 PF17503.2 CBY42980.1 - 0.13 12.0 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Zip PF02535.22 CBY42981.1 - 6.5e-31 107.8 2.0 8e-31 107.5 2.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter GLTT PF01744.20 CBY42981.1 - 0.065 13.0 0.7 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) UPF0370 PF13980.6 CBY42981.1 - 0.077 13.0 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF1304 PF06993.12 CBY42982.1 - 0.034 14.1 0.8 0.039 13.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Claudin_3 PF06653.11 CBY42982.1 - 0.082 12.9 4.1 0.11 12.4 4.1 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like P4Ha_N PF08336.11 CBY42983.1 - 8e-20 71.2 0.2 1.5e-19 70.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Not3 PF04065.15 CBY42983.1 - 0.036 13.5 4.6 0.062 12.7 4.6 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component MEDS PF14417.6 CBY42983.1 - 0.12 12.2 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain EGF_CA PF07645.15 CBY42984.1 - 3e-33 113.8 134.9 5.6e-11 42.5 11.9 7.3 7 0 0 7 7 7 6 Calcium-binding EGF domain cEGF PF12662.7 CBY42984.1 - 3.9e-16 58.6 84.5 1.4e-05 24.9 5.5 10.6 8 2 0 8 8 8 6 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY42984.1 - 8.4e-13 48.3 121.3 0.0084 16.3 12.6 8.0 6 2 1 7 7 7 6 EGF domain hEGF PF12661.7 CBY42984.1 - 0.0035 17.9 89.4 0.048 14.3 5.5 10.1 8 1 0 8 8 8 4 Human growth factor-like EGF EGF PF00008.27 CBY42984.1 - 0.0039 17.5 104.8 0.28 11.5 0.7 8.6 7 2 0 7 7 7 5 EGF-like domain TIL PF01826.17 CBY42984.1 - 0.032 14.5 5.1 0.032 14.5 5.1 8.2 6 3 1 7 7 7 0 Trypsin Inhibitor like cysteine rich domain Kringle PF00051.18 CBY42986.1 - 4.4e-46 155.1 18.0 1.7e-23 82.7 6.0 3.1 2 1 1 3 3 3 2 Kringle domain HTH_48 PF17906.1 CBY42986.1 - 0.06 13.5 0.3 8.4 6.6 0.1 2.7 2 0 0 2 2 2 0 HTH domain in Mos1 transposase HOOK PF05622.12 CBY42987.1 - 6.1e-68 229.6 42.1 7.6e-68 229.3 42.1 1.0 1 0 0 1 1 1 1 HOOK protein UPF0242 PF06785.11 CBY42987.1 - 0.32 11.1 49.7 0.32 11.1 8.8 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 CBY42987.1 - 0.8 9.8 50.5 0.84 9.7 9.0 4.0 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CBY42987.1 - 1.7 8.7 20.8 0.24 11.4 1.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Rho_Binding PF08912.11 CBY42987.1 - 4.5 8.2 40.1 0.085 13.7 7.1 5.0 2 2 3 5 5 5 0 Rho Binding Lebercilin PF15619.6 CBY42987.1 - 6 6.5 51.3 0.036 13.7 7.2 3.6 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 CBY42987.1 - 9 5.5 29.9 1.8 7.9 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CS PF04969.16 CBY42989.1 - 8.3e-15 55.6 1.1 1.8e-14 54.5 1.1 1.6 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CBY42989.1 - 2.2e-13 50.0 0.7 4.2e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. PIH1_CS PF18201.1 CBY42989.1 - 0.0034 17.8 0.1 0.0074 16.7 0.1 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain NuDC PF16273.5 CBY42989.1 - 0.015 15.8 13.2 0.015 15.8 13.2 3.1 1 1 1 2 2 2 0 Nuclear distribution C domain IF2_assoc PF08364.11 CBY42989.1 - 0.081 13.2 0.6 0.19 12.0 0.6 1.6 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region Nitro_FeMo-Co PF02579.17 CBY42989.1 - 0.63 10.4 4.1 2.8 8.3 0.2 2.5 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Guanylate_cyc PF00211.20 CBY42991.1 - 3e-47 160.6 0.0 5e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AA_permease PF00324.21 CBY42991.1 - 0.0051 15.5 0.5 0.0051 15.5 0.5 1.5 2 0 0 2 2 2 1 Amino acid permease MgtE PF01769.16 CBY42991.1 - 0.13 12.7 2.1 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Divalent cation transporter DUF1053 PF06327.14 CBY42991.1 - 0.33 11.5 1.1 0.63 10.6 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) TTL PF03133.15 CBY42992.1 - 0.00033 19.9 0.0 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family OSK PF17182.4 CBY42993.1 - 0.024 13.9 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 OSK domain NHR2 PF08788.11 CBY42993.1 - 0.049 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 NHR2 domain like DUF1993 PF09351.10 CBY42994.1 - 0.049 13.8 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Mito_carr PF00153.27 CBY42994.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein Gal_Lectin PF02140.18 CBY42995.1 - 4.8e-15 55.8 3.7 2.9e-07 30.8 0.2 2.3 2 0 0 2 2 2 2 Galactose binding lectin domain p47_phox_C PF08944.11 CBY42997.1 - 3.8 7.0 11.2 1.5 8.3 3.1 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Cyt-b5 PF00173.28 CBY42998.1 - 6.2e-09 35.9 0.0 8.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GST_N_3 PF13417.6 CBY42999.1 - 1.4e-09 38.2 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBY42999.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.6 CBY42999.1 - 3.3e-05 24.1 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBY42999.1 - 8.4e-05 22.8 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CBY42999.1 - 0.0049 17.6 0.0 0.015 16.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF836 PF05768.14 CBY42999.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) tRNA_bind PF01588.20 CBY43000.1 - 1.4e-29 102.0 0.3 3e-29 101.0 0.3 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain CCD48 PF15799.5 CBY43000.1 - 0.0013 17.1 2.7 0.0018 16.7 2.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 APC_N_CC PF16689.5 CBY43000.1 - 0.017 15.2 0.9 0.062 13.4 0.7 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DDHD PF02862.17 CBY43000.1 - 0.066 13.4 2.3 0.078 13.1 2.3 1.2 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 CBY43000.1 - 0.11 12.0 6.6 0.13 11.7 6.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RP-C_C PF11800.8 CBY43000.1 - 0.11 12.6 5.0 0.15 12.1 5.0 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region RNA_pol_Rpc4 PF05132.14 CBY43000.1 - 0.21 12.0 11.0 0.37 11.2 11.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CBY43000.1 - 0.33 10.7 15.2 0.46 10.3 15.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SKA1 PF07160.12 CBY43000.1 - 0.7 9.7 18.3 0.96 9.2 18.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Neur_chan_memb PF02932.16 CBY43000.1 - 1.1 9.3 3.3 1.3 9.0 3.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.12 CBY43000.1 - 1.5 9.1 12.0 2.1 8.6 12.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 CBY43000.1 - 1.8 7.5 5.9 2.4 7.0 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CBY43000.1 - 1.9 7.2 6.8 2.2 6.9 6.8 1.1 1 0 0 1 1 1 0 Presenilin YabA PF06156.13 CBY43000.1 - 2.3 8.9 6.5 7 7.4 6.5 1.8 1 1 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 CBY43000.1 - 2.7 5.8 6.2 3.4 5.5 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.8 CBY43000.1 - 3.8 6.2 12.5 5.3 5.7 12.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 CBY43000.1 - 8.8 6.0 6.6 12 5.6 6.6 1.2 1 0 0 1 1 1 0 Connexin Asp_protease_2 PF13650.6 CBY43001.1 - 0.00022 21.8 0.0 0.0007 20.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBY43001.1 - 0.00024 21.6 0.0 0.00077 20.0 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RnfC_N PF13375.6 CBY43001.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain EF-hand_1 PF00036.32 CBY43002.1 - 9e-06 24.9 0.3 1.6e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY43002.1 - 1.3e-05 25.6 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBY43002.1 - 1.3e-05 24.7 0.2 2.5e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CBY43002.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CBY43002.1 - 0.00066 19.5 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair Peptidase_M99 PF17033.5 CBY43002.1 - 0.079 12.4 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic SURF4 PF02077.15 CBY43003.1 - 7.6e-43 147.0 2.2 9.1e-43 146.8 2.2 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CBY43003.1 - 0.00016 22.2 2.1 0.00016 22.2 2.1 2.4 2 1 1 3 3 3 1 DoxX Histone PF00125.24 CBY43004.1 - 2e-21 76.7 0.5 2.5e-21 76.4 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY43004.1 - 4.6e-07 30.0 0.1 8.6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY43004.1 - 3.3e-05 24.3 0.0 5.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY43004.1 - 0.00099 19.2 0.2 0.0012 18.9 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY43004.1 - 0.062 13.5 0.1 0.083 13.1 0.1 1.1 1 0 0 1 1 1 0 CENP-W protein Sulfotransfer_2 PF03567.14 CBY43005.1 - 1.2e-09 38.5 0.1 1.2e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase family Ivy PF08816.11 CBY43007.1 - 0.055 13.7 4.2 2.1 8.6 0.1 2.1 1 1 1 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) eIF2_C PF09173.11 CBY43008.1 - 1.2e-32 112.0 0.2 2.1e-32 111.2 0.2 1.4 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CBY43008.1 - 1.9e-06 27.5 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBY43008.1 - 5.4e-06 26.7 0.2 1.3e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 CBY43008.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TFIIF_beta_N PF17683.1 CBY43010.1 - 1.4e-10 42.0 0.6 1.8e-10 41.7 0.1 1.4 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus DHHC PF01529.20 CBY43011.1 - 4.4e-28 98.0 11.3 4.4e-28 98.0 11.3 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.21 CBY43011.1 - 2.2 8.5 13.1 5.4 7.2 13.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger PGK PF00162.19 CBY43012.1 - 9.1e-40 136.8 5.1 1e-39 136.6 5.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Piwi PF02171.17 CBY43013.1 - 6.3e-36 124.2 0.2 7.5e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Piwi domain PG_binding_1 PF01471.18 CBY43016.1 - 2.4e-05 24.5 0.1 1.6 9.0 0.0 3.8 4 0 0 4 4 4 2 Putative peptidoglycan binding domain Ribosomal_S18 PF01084.20 CBY43016.1 - 0.0018 18.5 0.0 0.15 12.3 0.0 3.1 2 0 0 2 2 2 1 Ribosomal protein S18 PG_binding_2 PF08823.11 CBY43016.1 - 0.0078 16.5 0.0 43 4.5 0.0 4.2 3 1 2 5 5 5 1 Putative peptidoglycan binding domain UAA PF08449.11 CBY43019.1 - 1.4e-39 136.1 23.8 1.7e-39 135.9 23.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CBY43019.1 - 9.4e-13 48.1 21.1 1.7e-12 47.3 21.1 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBY43019.1 - 8.6e-11 42.2 36.1 6.3e-06 26.4 14.3 2.7 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CBY43019.1 - 2.4e-07 30.2 14.3 2.4e-07 30.2 14.3 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 CBY43019.1 - 8.2e-06 25.3 23.6 1.2e-05 24.8 23.6 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 CBY43019.1 - 0.00011 21.3 28.2 0.00027 20.0 6.8 2.1 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like DUF3479 PF11965.8 CBY43019.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) GAPES4 PF17157.4 CBY43019.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain RIH_assoc PF08454.11 CBY43019.1 - 0.27 11.1 1.7 0.69 9.8 1.7 1.7 1 1 0 1 1 1 0 RyR and IP3R Homology associated DUF4533 PF15047.6 CBY43021.1 - 0.015 14.9 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF4487 PF14868.6 CBY43021.1 - 0.069 12.0 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Sulfotransfer_2 PF03567.14 CBY43025.1 - 3e-07 30.6 3.9 4.5e-07 30.0 3.9 1.3 1 0 0 1 1 1 1 Sulfotransferase family Trehalase PF01204.18 CBY43027.1 - 2e-61 208.4 0.7 2.5e-61 208.1 0.7 1.0 1 0 0 1 1 1 1 Trehalase mRNA_triPase PF02940.15 CBY43027.1 - 0.046 13.4 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain COMPASS-Shg1 PF05205.12 CBY43027.1 - 0.075 13.7 0.3 2.2 9.0 0.1 2.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Pkinase PF00069.25 CBY43028.1 - 4e-56 190.3 0.0 5.1e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43028.1 - 1.4e-43 149.0 0.0 2.1e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY43028.1 - 0.0023 16.9 0.1 0.02 13.9 0.0 2.1 1 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CBY43028.1 - 0.0084 15.5 0.0 0.015 14.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY43028.1 - 0.022 14.7 0.1 0.082 12.8 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY43028.1 - 0.056 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Collagen PF01391.18 CBY43029.1 - 5.8e-27 93.2 90.3 4.7e-07 29.5 29.2 4.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Nudix_hydro PF18290.1 CBY43030.1 - 7.2e-24 83.6 0.1 1.2e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 CBY43030.1 - 2.8e-23 82.4 0.0 5.7e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain IP_trans PF02121.18 CBY43033.1 - 1.2e-96 323.0 4.1 1.7e-96 322.6 4.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TMEM189_B_dmain PF10520.9 CBY43035.1 - 4.9e-10 39.8 0.2 7.9e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain DUF3007 PF11460.8 CBY43035.1 - 0.0015 18.8 0.8 0.0024 18.1 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3007) FUN14 PF04930.15 CBY43037.1 - 1.8e-09 37.9 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 FUN14 family DUF1275 PF06912.11 CBY43037.1 - 0.043 13.7 0.2 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) RRP7 PF12923.7 CBY43038.1 - 5.8e-21 74.8 20.8 6.3e-21 74.7 20.8 1.0 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Acetyltransf_2 PF00797.17 CBY43038.1 - 0.11 12.3 1.7 0.12 12.2 1.7 1.1 1 0 0 1 1 1 0 N-acetyltransferase Vasculin PF15337.6 CBY43038.1 - 0.4 11.5 4.8 0.52 11.2 4.7 1.3 1 1 0 1 1 1 0 Vascular protein family Vasculin-like 1 Wzz PF02706.15 CBY43039.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Chain length determinant protein O-antigen_lig PF13425.6 CBY43039.1 - 0.05 12.4 2.6 0.068 12.0 2.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein GP67 PF17634.2 CBY43039.1 - 0.24 11.8 4.4 0.15 12.5 2.1 1.8 2 0 0 2 2 2 0 Gene product 67 ECH_1 PF00378.20 CBY43040.1 - 2.1e-07 30.5 1.2 2.4e-07 30.3 1.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-RING_2 PF13639.6 CBY43041.1 - 2.8e-12 46.8 10.4 2.8e-12 46.8 10.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CBY43041.1 - 7.4e-08 32.0 7.0 7.4e-08 32.0 7.0 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY43041.1 - 9.8e-08 31.7 10.1 9.8e-08 31.7 10.1 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY43041.1 - 3.9e-07 30.3 10.2 3.9e-07 30.3 10.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 CBY43041.1 - 1.1e-05 25.5 6.7 1.1e-05 25.5 6.7 2.4 2 0 0 2 2 2 1 zinc-ribbon zf-RING_UBOX PF13445.6 CBY43041.1 - 4.2e-05 23.5 3.8 4.2e-05 23.5 3.8 2.3 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY43041.1 - 7.8e-05 22.6 7.8 7.8e-05 22.6 7.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY43041.1 - 0.0002 21.1 9.5 0.0002 21.1 9.5 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBY43041.1 - 0.00073 19.5 4.5 0.00073 19.5 4.5 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 CBY43041.1 - 0.0018 18.2 0.7 0.0018 18.2 0.7 1.6 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 CBY43041.1 - 0.0021 17.6 9.8 0.0021 17.6 9.8 2.6 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBY43041.1 - 0.0022 17.8 9.9 0.0022 17.8 9.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY43041.1 - 0.0024 17.7 10.5 0.0024 17.7 10.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CBY43041.1 - 0.0045 16.9 4.7 0.0045 16.9 4.7 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 Rtf2 PF04641.12 CBY43041.1 - 1.5 8.2 8.2 0.042 13.2 1.2 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger Zf_RING PF16744.5 CBY43041.1 - 2.2 8.4 16.9 0.91 9.7 5.3 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger MAM1 PF10434.9 CBY43041.1 - 2.3 7.7 4.0 0.66 9.5 0.1 1.8 2 0 0 2 2 2 0 Monopolin complex protein MAM1 Trm112p PF03966.16 CBY43041.1 - 6.2 7.5 7.6 13 6.5 0.7 3.0 3 0 0 3 3 3 0 Trm112p-like protein HypA PF01155.19 CBY43041.1 - 6.4 6.8 16.8 0.81 9.7 3.2 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA T-box PF00907.22 CBY43044.1 - 7.3e-19 68.7 0.8 1.7e-18 67.5 0.8 1.6 1 0 0 1 1 1 1 T-box Tubulin_2 PF13809.6 CBY43044.1 - 0.023 13.9 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Tubulin like CDV3 PF15359.6 CBY43045.1 - 8.3 6.9 8.0 29 5.1 1.0 3.0 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Ly49 PF08391.10 CBY43046.1 - 8.8 6.7 7.6 2.9 8.3 0.6 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Peptidase_S8 PF00082.22 CBY43047.1 - 3.1e-05 23.4 0.0 7.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Subtilase family RRM_1 PF00076.22 CBY43048.1 - 0.00036 20.3 0.0 0.00041 20.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY43048.1 - 0.017 15.2 0.0 0.018 15.1 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif tRNA_m1G_MT PF01746.21 CBY43048.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase eIF-6 PF01912.18 CBY43049.1 - 3.7e-82 274.5 1.4 4.3e-82 274.3 1.0 1.3 2 0 0 2 2 2 1 eIF-6 family SOBP PF15279.6 CBY43051.1 - 1.2 9.7 36.6 0.61 10.6 34.1 1.6 1 1 0 1 1 1 0 Sine oculis-binding protein RNA_pol_Rpb6 PF01192.22 CBY43052.1 - 0.044 13.7 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb6 Cu_bind_like PF02298.17 CBY43052.1 - 0.097 12.7 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Plastocyanin-like domain DUF1690 PF07956.11 CBY43052.1 - 2.4 8.6 9.0 0.31 11.5 2.3 2.8 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) AAA-ATPase_like PF09820.9 CBY43053.1 - 0.094 12.1 0.0 0.099 12.0 0.0 1.0 1 0 0 1 1 1 0 Predicted AAA-ATPase Gla PF00594.20 CBY43055.1 - 1e-10 41.6 4.7 1e-10 41.6 4.7 1.6 2 0 0 2 2 2 1 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain HflK_N PF12221.8 CBY43055.1 - 0.071 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Sec1 PF00995.23 CBY43056.1 - 1.1e-07 31.6 0.3 1.2e-07 31.4 0.3 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 CBY43057.1 - 4.2e-20 72.5 0.1 4.7e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Sec1 family DUF1803 PF08820.10 CBY43057.1 - 0.052 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) zf-C2H2 PF00096.26 CBY43058.1 - 1.9e-05 24.9 35.4 0.00053 20.3 2.6 5.8 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY43058.1 - 0.0027 18.4 35.0 0.011 16.5 1.5 5.7 6 1 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY43058.1 - 0.0031 17.8 21.7 1.1 9.8 0.8 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CBY43058.1 - 0.019 14.6 16.7 0.12 12.0 0.1 4.3 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 CBY43058.1 - 0.029 14.1 3.6 0.029 14.1 3.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Elf1 PF05129.13 CBY43058.1 - 2 8.5 8.8 8.3 6.5 6.6 2.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Mss51 PF13824.6 CBY43058.1 - 5.9 7.1 11.8 0.32 11.1 0.6 3.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Lectin_C PF00059.21 CBY43059.1 - 8.7e-05 23.2 1.4 0.00044 20.9 0.0 2.4 3 0 0 3 3 3 1 Lectin C-type domain DUF5010_C PF18099.1 CBY43059.1 - 0.0086 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain Creatinase_N_2 PF16189.5 CBY43060.1 - 1.6e-37 129.1 0.0 2.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 CBY43060.1 - 1.6e-17 64.4 0.0 4.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ITI_HC_C PF06668.12 CBY43062.1 - 2.2e-06 27.4 0.0 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Inter-alpha-trypsin inhibitor heavy chain C-terminus EGF_CA PF07645.15 CBY43063.1 - 1.1e-09 38.4 2.5 1.4e-09 38.0 2.5 1.2 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 CBY43063.1 - 0.012 15.8 1.1 0.012 15.8 1.1 1.4 1 1 0 1 1 1 0 EGF domain Phospholip_A2_1 PF00068.19 CBY43064.1 - 2.9e-17 63.1 6.0 4.3e-17 62.6 6.0 1.2 1 0 0 1 1 1 1 Phospholipase A2 RIBIOP_C PF04950.12 CBY43065.1 - 5.2e-06 26.1 0.0 5.2e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal HYLS1_C PF15311.6 CBY43065.1 - 2 9.2 15.9 0.32 11.8 5.2 2.6 2 1 1 3 3 3 0 Hydrolethalus syndrome protein 1 C-terminus DUF2207 PF09972.9 CBY43067.1 - 0.01 14.6 1.8 0.011 14.5 1.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PIRT PF15099.6 CBY43067.1 - 0.031 13.8 0.4 0.036 13.7 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family WHEP-TRS PF00458.20 CBY43069.1 - 3.4e-81 267.3 54.7 5.4e-18 64.9 6.1 5.5 5 0 0 5 5 5 5 WHEP-TRS domain tRNA-synt_1c_C PF03950.18 CBY43069.1 - 1e-25 90.6 0.3 2e-25 89.7 0.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain RuvC PF02075.17 CBY43069.1 - 0.017 15.0 2.8 13 5.6 0.0 3.5 3 0 0 3 3 3 0 Crossover junction endodeoxyribonuclease RuvC ApbA_C PF08546.11 CBY43069.1 - 0.064 13.5 3.5 39 4.5 0.0 4.0 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal WIYLD PF10440.9 CBY43069.1 - 0.34 10.7 3.1 44 4.0 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-binding WIYLD domain Kinesin_assoc PF16183.5 CBY43069.1 - 0.41 10.8 3.7 48 4.0 0.0 3.9 1 1 4 5 5 5 0 Kinesin-associated DUF4298 PF14131.6 CBY43070.1 - 0.15 12.0 0.8 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF2382 PF09557.10 CBY43071.1 - 0.063 13.5 5.7 0.098 12.9 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) UCH PF00443.29 CBY43072.1 - 7.1e-12 45.4 0.0 7.1e-12 45.4 0.0 2.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase eIF-5_eIF-2B PF01873.17 CBY43073.1 - 1.2e-39 134.8 0.4 6.1e-39 132.5 0.2 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CBY43073.1 - 4.2e-16 58.9 3.5 4.2e-16 58.9 3.5 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Antimicrobial_6 PF08036.11 CBY43073.1 - 0.057 13.5 0.5 0.11 12.6 0.5 1.4 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide UPF0561 PF10573.9 CBY43073.1 - 0.15 12.2 1.0 0.23 11.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Pkinase PF00069.25 CBY43074.1 - 2.8e-45 154.7 0.0 5.7e-45 153.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43074.1 - 5.5e-29 101.2 0.0 1.5e-20 73.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY43074.1 - 3.8e-05 22.6 0.0 5.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY43074.1 - 0.025 13.9 0.2 0.053 12.9 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBY43074.1 - 0.051 13.1 0.1 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 CBY43074.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CBY43074.1 - 0.19 11.6 0.1 0.61 10.0 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family La PF05383.17 CBY43076.1 - 4.1e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY43076.1 - 0.00022 21.0 0.0 0.22 11.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MscS_porin PF12795.7 CBY43076.1 - 0.18 11.3 16.9 0.31 10.5 16.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1690 PF07956.11 CBY43076.1 - 6.1 7.3 8.2 1.7 9.0 5.0 1.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) RhoGAP PF00620.27 CBY43077.1 - 4.3e-06 26.6 0.7 1.3e-05 25.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain PriC PF07445.12 CBY43077.1 - 0.0029 17.6 19.4 0.22 11.5 13.3 3.2 2 1 0 2 2 2 2 Primosomal replication protein priC FCH PF00611.23 CBY43077.1 - 0.11 12.8 7.5 4.8 7.5 1.1 3.2 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain EF-hand_13 PF17958.1 CBY43078.1 - 0.022 14.6 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Iso_dh PF00180.20 CBY43080.1 - 8.5e-35 120.5 0.0 9.8e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IDH PF03971.14 CBY43080.1 - 0.025 13.0 1.0 0.032 12.7 1.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase ExbD PF02472.16 CBY43081.1 - 0.09 12.9 0.1 0.094 12.9 0.1 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR MFS_1 PF07690.16 CBY43084.1 - 2.9e-13 49.5 2.7 3.3e-13 49.3 2.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CBY43084.1 - 0.00054 19.4 1.0 0.00075 18.9 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 CBY43084.1 - 0.0041 15.8 0.4 0.0057 15.3 0.2 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like UL20 PF17582.2 CBY43084.1 - 0.018 14.4 0.1 0.028 13.7 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20 Gram_pos_anchor PF00746.21 CBY43084.1 - 0.079 12.9 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif 7TMR-DISM_7TM PF07695.11 CBY43084.1 - 0.52 10.2 9.5 6.8 6.5 1.9 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF202 PF02656.15 CBY43084.1 - 0.94 10.0 5.0 4.7 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MH1 PF03165.16 CBY43086.1 - 1.7e-06 28.1 0.1 2.3e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 MH1 domain VATC PF18716.1 CBY43088.1 - 1.8e-11 43.7 1.8 3.3e-11 42.9 1.8 1.4 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_5 PF13857.6 CBY43088.1 - 2.9e-06 27.4 0.0 5.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBY43088.1 - 0.00037 21.0 0.0 0.00053 20.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY43088.1 - 0.00044 20.5 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 CBY43088.1 - 0.00047 20.5 0.1 0.00085 19.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CBY43088.1 - 0.0042 17.6 0.0 0.0093 16.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NICE-3 PF07406.11 CBY43089.1 - 6e-10 39.4 0.1 7.4e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 NICE-3 protein BORCS6 PF10157.9 CBY43089.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Med25 PF11232.8 CBY43090.1 - 3.6e-39 134.2 1.0 3.6e-39 134.2 1.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Ndc1_Nup PF09531.10 CBY43090.1 - 2.5 6.7 4.4 2.7 6.6 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gon7 PF08738.10 CBY43092.1 - 0.1 12.7 1.6 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Gon7 family DUF4805 PF16063.5 CBY43092.1 - 0.42 9.9 4.2 0.64 9.3 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) TSP_1 PF00090.19 CBY43093.1 - 9.1e-19 67.4 53.1 3.1e-11 43.3 5.5 4.8 4 1 0 4 4 4 3 Thrombospondin type 1 domain zf-CCCH PF00642.24 CBY43093.1 - 0.028 14.3 3.5 5.6 7.0 0.5 3.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBY43093.1 - 7.7 6.7 10.0 4.4 7.5 0.8 3.4 3 0 0 3 3 3 0 Zinc finger domain DUF846 PF05832.12 CBY43094.1 - 3.1e-45 153.6 2.1 3.8e-45 153.3 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) PP2 PF14299.6 CBY43095.1 - 1.5e-05 25.1 1.2 3.9e-05 23.7 1.2 1.6 1 1 0 1 1 1 1 Phloem protein 2 zf-RING_5 PF14634.6 CBY43097.1 - 2.5e-05 24.1 12.9 2.5e-05 24.1 12.9 3.3 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY43097.1 - 7.4e-05 23.0 12.8 7.4e-05 23.0 12.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY43097.1 - 0.00026 20.8 12.2 0.00026 20.8 12.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY43097.1 - 0.0014 18.5 13.8 0.0014 18.5 13.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY43097.1 - 0.0016 18.2 10.5 0.0016 18.2 10.5 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY43097.1 - 0.0017 18.3 6.6 0.0017 18.3 6.6 3.3 3 1 1 4 4 4 1 RING-type zinc-finger DUF745 PF05335.13 CBY43097.1 - 0.0023 17.7 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) zf-RING_4 PF14570.6 CBY43097.1 - 0.012 15.3 7.6 0.012 15.3 7.6 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain YscO-like PF16789.5 CBY43097.1 - 0.045 13.8 5.4 0.078 13.0 5.4 1.4 1 0 0 1 1 1 0 YscO-like protein BORCS7 PF16088.5 CBY43097.1 - 0.085 13.1 2.1 0.14 12.5 2.1 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF16 PF01519.16 CBY43097.1 - 0.097 13.2 5.4 0.15 12.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 zf-rbx1 PF12678.7 CBY43097.1 - 0.19 12.1 9.1 0.28 11.5 7.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CBY43097.1 - 0.5 10.6 16.0 0.43 10.8 12.0 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 CBY43097.1 - 5.7 7.2 13.6 0.14 12.3 3.9 2.9 2 1 0 2 2 2 0 Zinc ribbon domain DNA_primase_S PF01896.19 CBY43098.1 - 4.8e-45 153.8 0.7 7.4e-45 153.2 0.7 1.3 1 0 0 1 1 1 1 DNA primase small subunit Carbpep_Y_N PF05388.11 CBY43098.1 - 0.044 14.3 0.2 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Peptidase_M24 PF00557.24 CBY43099.1 - 5.1e-05 23.1 0.0 5.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S25 PF03297.15 CBY43099.1 - 0.05 13.8 0.5 0.093 12.9 0.1 1.6 2 0 0 2 2 2 0 S25 ribosomal protein LodA_C PF18417.1 CBY43099.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine epsilon oxidase C-terminal domain cEGF PF12662.7 CBY43100.1 - 4e-10 39.4 20.4 1.4e-05 24.9 0.7 3.8 3 0 0 3 3 3 3 Complement Clr-like EGF-like EGF_CA PF07645.15 CBY43100.1 - 4.6e-10 39.5 34.8 3e-07 30.5 11.2 3.3 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY43100.1 - 8.2e-09 35.6 29.8 2.9e-07 30.7 5.9 3.6 2 1 1 3 3 3 3 Coagulation Factor Xa inhibitory site EGF PF00008.27 CBY43100.1 - 1.6e-08 34.7 28.2 2.4e-06 27.7 6.8 4.0 3 1 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 CBY43100.1 - 6.6e-05 23.0 28.7 0.0056 16.9 5.1 3.8 3 2 0 3 3 3 2 EGF domain EGF_2 PF07974.13 CBY43100.1 - 0.008 16.5 8.5 0.008 16.5 8.5 3.7 2 1 1 3 3 3 1 EGF-like domain Plasmod_Pvs28 PF06247.11 CBY43100.1 - 0.075 13.4 23.4 2 8.8 3.6 3.3 2 1 0 2 2 2 0 Pvs28 EGF domain hEGF PF12661.7 CBY43100.1 - 0.11 13.2 2.0 0.11 13.2 2.0 4.8 5 2 0 5 5 5 0 Human growth factor-like EGF cEGF PF12662.7 CBY43102.1 - 2e-10 40.4 2.3 3.7e-10 39.5 2.3 1.5 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 CBY43102.1 - 3.8e-09 36.7 5.8 3.5e-05 24.0 0.2 2.1 2 0 0 2 2 2 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.15 CBY43102.1 - 0.00068 19.8 10.5 0.044 14.0 1.7 2.1 2 0 0 2 2 2 2 Calcium-binding EGF domain TIL PF01826.17 CBY43102.1 - 0.022 15.0 0.5 0.022 15.0 0.5 1.8 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain EGF PF00008.27 CBY43102.1 - 0.12 12.8 8.2 0.25 11.7 0.2 3.0 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 CBY43102.1 - 0.48 11.1 9.0 0.67 10.7 0.5 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF COG4 PF08318.12 CBY43106.1 - 0.03 13.4 0.2 0.05 12.7 0.2 1.3 1 0 0 1 1 1 0 COG4 transport protein HLH PF00010.26 CBY43107.1 - 2.9e-12 46.4 0.2 6e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_11 PF14598.6 CBY43107.1 - 0.06 13.5 0.1 0.63 10.2 0.0 2.4 3 0 0 3 3 3 0 PAS domain DUF2744 PF10910.8 CBY43108.1 - 0.046 13.7 0.0 0.061 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2744) DUF4551 PF15087.6 CBY43108.1 - 0.54 9.0 6.4 0.58 8.9 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 CBY43110.1 - 9.4e-11 41.6 0.3 1.1e-10 41.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43110.1 - 8.8e-10 38.3 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Per1 PF04080.13 CBY43111.1 - 5.5e-12 46.0 0.3 5.9e-12 45.9 0.3 1.0 1 0 0 1 1 1 1 Per1-like family DUF4905 PF16248.5 CBY43111.1 - 0.09 12.7 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4905) Per1 PF04080.13 CBY43112.1 - 4.5e-19 69.2 1.5 4.9e-19 69.1 1.5 1.0 1 0 0 1 1 1 1 Per1-like family ThiF PF00899.21 CBY43113.1 - 2.2e-21 76.4 0.0 2.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family RGS PF00615.19 CBY43115.1 - 1.4e-12 47.9 1.7 7e-08 32.8 0.5 2.7 3 0 0 3 3 3 2 Regulator of G protein signaling domain EIIA-man PF03610.16 CBY43117.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 PTS system fructose IIA component F-box-like PF12937.7 CBY43118.1 - 1.7e-06 27.8 1.1 3e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CBY43118.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 2 0 0 2 2 2 1 F-box domain Rhomboid PF01694.22 CBY43119.1 - 6.5e-16 58.7 3.6 1.3e-15 57.7 3.6 1.4 1 0 0 1 1 1 1 Rhomboid family Myosin_head PF00063.21 CBY43120.1 - 8e-55 186.3 0.4 9.8e-55 186.0 0.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 CBY43120.1 - 0.002 18.6 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY43120.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBY43120.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_6 PF12774.7 CBY43120.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 CBY43120.1 - 0.058 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 ABC transporter HutP PF09021.11 CBY43120.1 - 0.14 12.5 0.1 0.31 11.4 0.1 1.6 2 0 0 2 2 2 0 HutP PC-Esterase PF13839.6 CBY43121.1 - 0.00059 19.7 0.1 0.0006 19.6 0.1 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GalP_UDP_tr_C PF02744.17 CBY43122.1 - 3.8e-58 195.9 0.0 4.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CBY43122.1 - 8.4e-12 45.9 0.3 1.7e-11 44.9 0.3 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain Itfg2 PF15907.5 CBY43123.1 - 0.032 13.3 0.1 0.04 13.0 0.1 1.1 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Polysacc_synt_4 PF04669.13 CBY43124.1 - 3.6e-09 36.5 0.1 0.00012 21.6 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis MADF_DNA_bdg PF10545.9 CBY43124.1 - 0.0012 19.1 0.2 0.0021 18.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Hrs_helical PF12210.8 CBY43126.1 - 4.4e-35 120.1 4.5 4.4e-35 120.1 4.5 2.8 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF1885 PF08968.10 CBY43126.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) DUF87 PF01935.17 CBY43128.1 - 0.51 10.4 3.8 0.19 11.8 0.7 1.7 1 1 1 2 2 2 0 Helicase HerA, central domain CG-1 PF03859.16 CBY43128.1 - 0.77 9.6 5.1 0.17 11.6 0.3 2.2 2 0 0 2 2 2 0 CG-1 domain bZIP_1 PF00170.21 CBY43128.1 - 1.2 9.3 17.4 0.39 10.9 11.8 2.9 2 1 0 2 2 2 0 bZIP transcription factor Exonuc_VII_L PF02601.15 CBY43128.1 - 1.7 8.2 9.4 2.2 7.8 9.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vac_Fusion PF02346.16 CBY43128.1 - 3.2 7.4 6.3 11 5.7 0.3 3.0 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Pkinase_Tyr PF07714.17 CBY43129.1 - 5.6e-12 45.5 0.0 6.2e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY43129.1 - 0.0022 17.4 0.0 0.0022 17.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Connexin PF00029.19 CBY43130.1 - 4.4e-27 95.4 0.2 5.9e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Connexin DHODB_Fe-S_bind PF10418.9 CBY43132.1 - 0.0048 16.7 1.5 0.64 9.9 0.2 3.1 3 0 0 3 3 3 2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NPBW PF15180.6 CBY43132.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Neuropeptides B and W Sulfotransfer_1 PF00685.27 CBY43133.1 - 3.9e-26 92.1 0.0 6.2e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CBY43133.1 - 1.3e-05 25.7 0.1 0.015 15.6 0.2 2.8 1 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_4 PF17784.1 CBY43133.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.4 1 1 0 1 1 1 0 Sulfotransferase domain HABP4_PAI-RBP1 PF04774.15 CBY43134.1 - 2.8e-14 54.0 13.0 2.8e-14 54.0 13.0 3.9 2 1 1 3 3 3 2 Hyaluronan / mRNA binding family RNase_T PF00929.24 CBY43136.1 - 6.4e-09 36.6 0.2 9.1e-09 36.1 0.2 1.5 1 1 0 1 1 1 1 Exonuclease PLAT PF01477.23 CBY43138.1 - 3.3e-19 69.6 0.4 1.7e-18 67.3 0.2 2.1 2 0 0 2 2 2 1 PLAT/LH2 domain Lipoxygenase PF00305.19 CBY43138.1 - 0.0004 18.9 0.0 0.0014 17.2 0.0 1.6 1 1 1 2 2 2 1 Lipoxygenase ATS3 PF06232.11 CBY43138.1 - 0.0051 16.7 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Embryo-specific protein 3, (ATS3) DUF2436 PF10365.9 CBY43138.1 - 0.09 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Trypsin PF00089.26 CBY43139.1 - 2.5e-59 200.8 0.5 3.6e-59 200.2 0.5 1.3 1 0 0 1 1 1 1 Trypsin EGF PF00008.27 CBY43139.1 - 2e-17 63.1 72.5 1.7e-06 28.2 10.3 5.9 5 0 0 5 5 5 5 EGF-like domain EGF_CA PF07645.15 CBY43139.1 - 4.5e-11 42.8 67.1 2.4e-07 30.8 8.2 6.1 2 2 3 5 5 4 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 CBY43139.1 - 2.1e-08 34.3 55.8 0.00021 21.5 6.8 6.2 2 2 3 5 5 5 3 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 CBY43139.1 - 1.6e-06 28.2 24.2 2.7e-05 24.2 6.9 6.0 5 0 0 5 5 5 2 EGF domain hEGF PF12661.7 CBY43139.1 - 9.2e-06 26.1 70.6 0.0024 18.4 6.8 7.6 7 1 0 7 7 7 5 Human growth factor-like EGF EGF_2 PF07974.13 CBY43139.1 - 0.00058 20.2 10.6 0.00058 20.2 10.6 6.1 5 0 0 5 5 5 3 EGF-like domain DUF1986 PF09342.11 CBY43139.1 - 0.0025 18.2 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) Plasmod_Pvs28 PF06247.11 CBY43139.1 - 0.0035 17.6 2.5 0.0035 17.6 2.5 5.0 5 0 0 5 5 5 2 Pvs28 EGF domain cEGF PF12662.7 CBY43139.1 - 0.024 14.6 1.2 0.024 14.6 1.2 5.7 6 0 0 6 6 6 0 Complement Clr-like EGF-like Atu4866 PF11512.8 CBY43139.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Aa_trans PF01490.18 CBY43140.1 - 1.8e-28 99.4 23.3 1.4e-21 76.7 10.5 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein EF-hand_1 PF00036.32 CBY43141.1 - 3.7e-17 60.5 18.7 0.00063 19.1 0.1 6.4 6 2 1 7 7 7 5 EF hand EF-hand_7 PF13499.6 CBY43141.1 - 1e-15 57.9 18.2 1.5e-08 34.9 0.9 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBY43141.1 - 2e-14 52.3 16.1 0.003 17.0 0.0 5.9 5 1 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBY43141.1 - 1.7e-11 43.1 14.1 0.056 13.4 0.1 6.2 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 CBY43141.1 - 2.1e-07 30.6 16.1 0.023 14.5 0.2 5.4 5 1 0 5 5 5 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBY43141.1 - 1.1e-05 25.7 15.9 0.0039 17.5 2.7 3.8 2 1 2 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Adenine_glyco PF03352.13 CBY43141.1 - 4.9e-05 23.2 0.3 0.0001 22.1 0.3 1.5 1 0 0 1 1 1 1 Methyladenine glycosylase EF-hand_10 PF14788.6 CBY43141.1 - 0.11 12.3 0.1 0.11 12.3 0.1 4.5 5 1 1 6 6 6 0 EF hand DUF4407 PF14362.6 CBY43141.1 - 0.27 10.6 0.4 0.42 9.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Unstab_antitox PF09720.10 CBY43141.1 - 2 8.6 6.5 4.5 7.4 1.2 3.3 3 0 0 3 3 3 0 Putative addiction module component zf-RING_2 PF13639.6 CBY43142.1 - 3.3e-11 43.3 3.1 5.1e-11 42.7 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBY43142.1 - 6.4e-10 38.7 3.6 1e-09 38.1 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBY43142.1 - 2.8e-08 33.5 3.0 5e-08 32.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBY43142.1 - 1.8e-06 27.7 1.7 2.8e-06 27.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBY43142.1 - 2e-06 28.0 3.1 6.5e-06 26.3 3.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY43142.1 - 5.6e-06 26.3 4.1 1.2e-05 25.3 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY43142.1 - 7.4e-06 25.8 3.8 1.2e-05 25.2 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBY43142.1 - 0.0002 21.0 3.3 0.0048 16.6 1.0 2.6 2 0 0 2 2 2 1 RING-like zinc finger Baculo_IE-1 PF05290.11 CBY43142.1 - 0.00097 19.1 2.3 0.0011 18.9 1.1 1.7 1 1 1 2 2 2 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 CBY43142.1 - 0.002 17.9 1.9 0.0044 16.8 1.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CBY43142.1 - 0.003 17.0 0.2 0.003 17.0 0.2 2.1 1 1 1 2 2 2 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CBY43142.1 - 0.0038 17.0 4.3 0.0064 16.3 4.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF2344 PF10105.9 CBY43142.1 - 0.033 14.0 2.5 0.044 13.6 2.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) zf-ANAPC11 PF12861.7 CBY43142.1 - 0.047 13.8 1.3 0.079 13.0 1.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MSA-2c PF12238.8 CBY43142.1 - 0.086 12.8 1.8 0.11 12.5 1.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c GAS PF13851.6 CBY43142.1 - 0.16 11.3 24.7 0.086 12.2 21.7 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C3HC4_4 PF15227.6 CBY43142.1 - 0.19 11.9 5.1 1 9.6 5.5 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING T6PP_N PF18572.1 CBY43142.1 - 3.1 7.7 10.9 2.6e+02 1.5 10.9 2.2 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain V_ATPase_I PF01496.19 CBY43142.1 - 4.2 5.2 8.6 5 4.9 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 CBY43142.1 - 4.6 6.5 16.9 0.69 9.2 11.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AAA_11 PF13086.6 CBY43142.1 - 9.4 5.9 12.3 12 5.5 12.3 1.1 1 0 0 1 1 1 0 AAA domain GD_AH_C PF04295.13 CBY43143.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus O-FucT PF10250.9 CBY43143.1 - 9.3 5.8 9.3 42 3.7 9.3 2.1 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Sep15_SelM PF08806.11 CBY43144.1 - 0.0081 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Sep15/SelM redox domain Mon2_C PF16206.5 CBY43145.1 - 0.016 13.4 0.3 0.027 12.7 0.3 1.5 1 1 0 1 1 1 0 C-terminal region of Mon2 protein CARD PF00619.21 CBY43146.1 - 0.014 15.4 1.5 4.1 7.5 0.0 3.3 4 0 0 4 4 4 0 Caspase recruitment domain Turandot PF07240.11 CBY43146.1 - 0.1 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Sulfatase_C PF14707.6 CBY43146.1 - 0.26 12.0 1.9 0.26 12.0 0.3 1.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF908 PF06012.12 CBY43146.1 - 0.49 9.7 5.0 0.98 8.8 3.1 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) ADIP PF11559.8 CBY43147.1 - 2.7e-05 24.3 7.2 3.4e-05 24.0 7.2 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Laminin_I PF06008.14 CBY43147.1 - 0.00031 20.6 2.0 0.00033 20.5 2.0 1.0 1 0 0 1 1 1 1 Laminin Domain I Cnn_1N PF07989.11 CBY43147.1 - 0.00086 19.4 1.3 0.00086 19.4 1.3 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 MscS_porin PF12795.7 CBY43147.1 - 0.0014 18.2 8.4 0.0019 17.8 8.4 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Tektin PF03148.14 CBY43147.1 - 0.0022 16.8 4.0 0.0026 16.6 4.0 1.1 1 0 0 1 1 1 1 Tektin family DivIVA PF05103.13 CBY43147.1 - 0.0026 17.8 4.4 0.012 15.7 4.2 1.8 1 1 0 1 1 1 1 DivIVA protein YlqD PF11068.8 CBY43147.1 - 0.0027 18.1 5.8 0.0032 17.8 5.8 1.0 1 0 0 1 1 1 1 YlqD protein DUF4874 PF16173.5 CBY43147.1 - 0.0036 17.0 0.3 0.0044 16.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) Herpes_UL33 PF03581.13 CBY43147.1 - 0.0054 17.1 0.4 0.011 16.1 0.2 1.5 1 1 1 2 2 2 1 Herpesvirus UL33-like protein HemX PF04375.14 CBY43147.1 - 0.0061 15.9 4.2 0.0071 15.7 4.2 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase APG6_N PF17675.1 CBY43147.1 - 0.0061 17.1 4.4 0.0073 16.8 4.4 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region HALZ PF02183.18 CBY43147.1 - 0.0074 16.5 1.2 0.0074 16.5 1.2 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Lebercilin PF15619.6 CBY43147.1 - 0.0083 15.8 7.8 0.0099 15.6 7.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Sulfatase_C PF14707.6 CBY43147.1 - 0.0097 16.6 0.4 0.01 16.5 0.4 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase HAUS5 PF14817.6 CBY43147.1 - 0.0099 14.7 3.8 0.012 14.4 3.8 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Mod_r PF07200.13 CBY43147.1 - 0.01 15.9 6.0 0.012 15.7 6.0 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF16 PF01519.16 CBY43147.1 - 0.013 16.0 2.7 0.025 15.1 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 CBY43147.1 - 0.014 15.6 1.4 1.3 9.2 1.0 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Helo_like_N PF17111.5 CBY43147.1 - 0.015 14.7 2.3 0.019 14.4 2.3 1.0 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF4763 PF15960.5 CBY43147.1 - 0.016 14.6 5.2 0.018 14.4 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4164 PF13747.6 CBY43147.1 - 0.016 15.5 2.8 0.023 15.0 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) G-7-MTase PF12803.7 CBY43147.1 - 0.019 14.1 0.5 0.021 14.0 0.5 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) UPF0242 PF06785.11 CBY43147.1 - 0.022 14.9 5.1 0.027 14.6 5.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IFT57 PF10498.9 CBY43147.1 - 0.022 13.7 3.2 0.025 13.6 3.2 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 YabA PF06156.13 CBY43147.1 - 0.022 15.4 4.3 0.034 14.8 4.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA GAS PF13851.6 CBY43147.1 - 0.028 13.8 9.3 0.035 13.5 9.3 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_N PF10481.9 CBY43147.1 - 0.029 14.0 5.3 0.03 13.9 4.6 1.4 1 1 1 2 2 2 0 Cenp-F N-terminal domain DUF2408 PF10303.9 CBY43147.1 - 0.038 14.6 2.3 0.045 14.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) MAD PF05557.13 CBY43147.1 - 0.043 12.2 6.0 0.053 11.9 6.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein PI3K_P85_iSH2 PF16454.5 CBY43147.1 - 0.044 13.4 7.4 0.12 11.9 6.8 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMPIT PF07851.13 CBY43147.1 - 0.068 12.4 2.6 0.072 12.3 2.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 CBY43147.1 - 0.077 13.0 7.8 0.19 11.7 7.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 CBY43147.1 - 0.079 10.5 4.0 0.092 10.2 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 CBY43147.1 - 0.094 13.2 10.6 0.14 12.6 10.6 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Vps51 PF08700.11 CBY43147.1 - 0.1 12.7 3.8 3.4 7.8 3.7 2.1 1 1 0 1 1 1 0 Vps51/Vps67 Prefoldin_2 PF01920.20 CBY43147.1 - 0.11 12.5 8.9 0.25 11.3 5.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit Spc7 PF08317.11 CBY43147.1 - 0.11 11.4 4.9 0.13 11.1 4.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Dzip-like_N PF13815.6 CBY43147.1 - 0.13 12.3 4.0 0.17 11.9 4.0 1.2 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FapA PF03961.13 CBY43147.1 - 0.13 10.9 2.1 0.14 10.7 2.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliD_C PF07195.12 CBY43147.1 - 0.15 11.5 3.3 0.18 11.2 3.3 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Spectrin PF00435.21 CBY43147.1 - 0.15 12.5 4.5 0.3 11.6 4.1 1.5 1 1 0 1 1 1 0 Spectrin repeat DUF4446 PF14584.6 CBY43147.1 - 0.15 12.0 2.0 0.19 11.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 CBY43147.1 - 0.23 11.9 2.6 6.4 7.3 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FAD-SLDH PF12318.8 CBY43147.1 - 0.24 11.4 1.0 0.28 11.2 1.0 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase SlyX PF04102.12 CBY43147.1 - 0.33 11.6 5.7 1.1 9.9 2.3 2.1 1 1 1 2 2 2 0 SlyX JAKMIP_CC3 PF16034.5 CBY43147.1 - 0.33 10.9 6.6 0.58 10.1 6.7 1.3 1 1 0 1 1 1 0 JAKMIP CC3 domain Uso1_p115_C PF04871.13 CBY43147.1 - 0.67 10.3 5.9 0.69 10.3 4.3 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 CBY43147.1 - 1.2 8.9 8.9 5.9 6.7 0.5 2.1 1 1 1 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 CBY43147.1 - 1.5 8.9 10.8 5.1 7.2 0.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 CBY43147.1 - 1.6 8.7 7.2 3.7 7.5 0.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit Tmpp129 PF10272.9 CBY43148.1 - 9e-40 137.1 7.2 4e-30 105.3 9.3 3.0 1 1 1 2 2 2 2 Putative transmembrane protein precursor zinc_ribbon_9 PF14369.6 CBY43148.1 - 0.072 13.4 0.8 0.072 13.4 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-RING_4 PF14570.6 CBY43148.1 - 0.76 9.6 8.3 2.4 8.0 8.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sacchrp_dh_NADP PF03435.18 CBY43150.1 - 1.7e-20 73.6 0.1 2.7e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBY43150.1 - 2.5e-07 30.8 0.0 3.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY43150.1 - 0.00012 21.2 0.0 0.00027 20.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CBY43150.1 - 0.00022 21.3 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CBY43150.1 - 0.0032 17.9 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CBY43150.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CBY43150.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.22 CBY43150.1 - 0.015 16.2 0.0 0.027 15.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PCI PF01399.27 CBY43151.1 - 4.2e-10 40.1 0.0 1.6e-09 38.2 0.0 1.8 1 1 1 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 CBY43151.1 - 1.4e-09 37.5 0.9 1.4e-09 37.5 0.9 2.4 2 1 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF4061 PF13270.6 CBY43151.1 - 0.09 13.1 1.8 2.3 8.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Tiam_CC_Ex PF18385.1 CBY43151.1 - 0.22 11.9 0.7 22 5.5 0.1 2.2 1 1 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain Enolase_C PF00113.22 CBY43152.1 - 2.2e-74 250.3 0.1 3.3e-74 249.8 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBY43152.1 - 1.3e-55 187.2 0.6 1.9e-55 186.6 0.6 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain Alpha-amylase_C PF02806.18 CBY43153.1 - 2.5e-22 79.1 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CPSase_L_D2 PF02786.17 CBY43154.1 - 3.7e-43 147.5 0.0 5.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CBY43154.1 - 3.2e-23 81.9 0.0 9.2e-23 80.4 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 CBY43154.1 - 9.9e-21 73.6 0.0 1.3e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Biotin_lipoyl PF00364.22 CBY43154.1 - 6.7e-10 38.7 0.3 1.6e-09 37.4 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY43154.1 - 0.013 15.3 0.0 0.06 13.2 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 CBY43154.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Asp5 PF17000.5 CBY43155.1 - 0.23 11.6 0.1 0.38 10.9 0.1 1.3 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 DUF1951 PF09188.10 CBY43157.1 - 0.027 14.5 0.2 0.059 13.4 0.1 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1951) ACC_central PF08326.12 CBY43159.1 - 9.7e-171 569.6 8.7 1.1e-170 569.4 8.7 1.0 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region DUF932 PF06067.11 CBY43159.1 - 0.03 14.1 0.2 5.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF932) LSM PF01423.22 CBY43160.1 - 0.03 14.0 0.2 0.042 13.5 0.2 1.3 1 0 0 1 1 1 0 LSM domain Aminotran_4 PF01063.19 CBY43163.1 - 3.4e-29 102.3 0.0 3.9e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV N2227 PF07942.12 CBY43163.1 - 0.00012 21.3 0.0 0.00061 19.1 0.0 1.8 2 0 0 2 2 2 1 N2227-like protein Kelch_1 PF01344.25 CBY43164.1 - 0.017 14.7 0.1 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 Kelch motif RT_RNaseH_2 PF17919.1 CBY43165.1 - 1.6e-25 89.0 0.0 3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY43165.1 - 7.9e-19 67.9 0.0 1.3e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CBY43165.1 - 1.9e-14 53.9 0.0 6.7e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CBY43165.1 - 4.6e-08 33.0 0.2 1e-07 31.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CBY43165.1 - 0.0011 19.1 0.6 0.0028 17.8 0.3 1.9 2 0 0 2 2 2 1 H2C2 zinc finger DNA_pol_viral_C PF00336.18 CBY43165.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain gag_pre-integrs PF13976.6 CBY43165.1 - 0.16 11.8 0.3 0.39 10.6 0.3 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain Aa_trans PF01490.18 CBY43166.1 - 4.5e-41 140.9 12.1 5.9e-41 140.5 12.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RR_TM4-6 PF06459.12 CBY43166.1 - 0.26 11.1 0.0 0.48 10.2 0.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAN_1 PF00024.26 CBY43169.1 - 0.0014 18.5 0.5 0.0014 18.5 0.5 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 CBY43169.1 - 0.0095 15.8 1.8 0.023 14.6 1.8 1.6 1 0 0 1 1 1 1 PAN domain COX7B PF05392.11 CBY43169.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Vma12 PF11712.8 CBY43169.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PRCC PF10253.9 CBY43170.1 - 7.1e-19 69.4 0.4 8.1e-19 69.3 0.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting THF_DHG_CYH_C PF02882.19 CBY43173.1 - 4.6e-38 130.0 0.0 6.9e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBY43173.1 - 6.4e-32 110.3 0.0 8.6e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Trypsin PF00089.26 CBY43174.1 - 2.7e-61 207.2 0.1 3.2e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY43174.1 - 6.2e-06 27.2 0.0 1.1e-05 26.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 CBY43174.1 - 0.00024 21.4 0.0 0.0007 20.0 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1986) DSL PF01414.19 CBY43175.1 - 3.1e-10 40.2 1.6 3.1e-10 40.2 1.6 4.1 3 1 0 3 3 3 1 Delta serrate ligand EGF_2 PF07974.13 CBY43175.1 - 0.007 16.7 11.5 0.007 16.7 11.5 4.8 4 1 1 5 5 5 1 EGF-like domain hEGF PF12661.7 CBY43175.1 - 2 9.2 25.6 0.11 13.1 7.3 4.9 4 0 0 4 4 4 0 Human growth factor-like EGF MFS_1_like PF12832.7 CBY43177.1 - 0.021 13.7 5.1 0.27 10.0 1.6 2.2 1 1 0 2 2 2 0 MFS_1 like family ATG22 PF11700.8 CBY43177.1 - 9.1 4.8 11.2 0.61 8.7 1.7 2.1 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Snapin_Pallidin PF14712.6 CBY43178.1 - 0.046 14.1 0.3 0.078 13.4 0.3 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF1963 PF09234.10 CBY43178.1 - 0.049 14.1 0.0 0.06 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Pox_A_type_inc PF04508.12 CBY43178.1 - 0.96 9.4 4.2 22 5.1 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Trefoil PF00088.18 CBY43182.1 - 1.8e-29 101.3 56.0 5.1e-09 35.9 5.8 4.5 4 0 0 4 4 4 4 Trefoil (P-type) domain 3-dmu-9_3-mt PF06983.13 CBY43182.1 - 0.49 10.9 1.6 20 5.8 0.0 2.7 3 0 0 3 3 3 0 3-demethylubiquinone-9 3-methyltransferase Calici_MSP PF05752.11 CBY43183.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3539 PF12058.8 CBY43183.1 - 0.17 12.1 0.0 1.4 9.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3539) Avl9 PF09794.9 CBY43184.1 - 6.5e-16 58.0 0.0 9.7e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 QslA_E PF18226.1 CBY43184.1 - 0.046 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E HECT PF00632.25 CBY43185.1 - 1.7e-56 192.0 0.0 2.4e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CBY43185.1 - 2.8e-39 132.9 14.7 7.4e-14 51.5 4.0 3.7 3 0 0 3 3 3 3 WW domain DUF1971 PF09313.11 CBY43185.1 - 0.073 13.1 1.0 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1971) zf-RING_2 PF13639.6 CBY43186.1 - 3.3e-10 40.1 8.4 6.8e-10 39.1 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBY43186.1 - 2.2e-06 27.9 7.5 5.9e-06 26.5 7.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBY43186.1 - 3.8e-06 26.8 5.3 8.9e-06 25.6 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBY43186.1 - 4.8e-06 26.3 10.0 1.1e-05 25.2 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY43186.1 - 1.8e-05 24.5 9.1 4.2e-05 23.3 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY43186.1 - 4.6e-05 23.2 5.2 0.00013 21.8 5.2 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBY43186.1 - 0.00011 22.0 7.8 0.00024 20.9 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY43186.1 - 0.00044 20.2 9.1 0.00091 19.1 9.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBY43186.1 - 0.005 16.9 2.3 0.013 15.6 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CBY43186.1 - 0.015 15.1 6.8 0.051 13.4 6.8 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 CBY43186.1 - 0.03 14.4 2.3 0.07 13.2 2.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 CBY43186.1 - 0.041 13.6 6.0 0.1 12.4 6.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Erp_C PF06780.11 CBY43186.1 - 0.068 13.2 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Erp protein C-terminus UPF0242 PF06785.11 CBY43186.1 - 0.08 13.0 1.1 0.17 12.0 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FANCL_C PF11793.8 CBY43186.1 - 0.081 13.1 8.4 0.6 10.3 8.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 CBY43186.1 - 0.34 11.1 7.0 1 9.6 7.0 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CBY43186.1 - 0.53 10.5 5.2 1.5 9.0 5.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GAS PF13851.6 CBY43186.1 - 0.67 9.3 6.3 0.47 9.8 3.8 2.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CBY43186.1 - 0.71 9.9 5.5 1.8 8.6 5.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Zn_ribbon_17 PF17120.5 CBY43186.1 - 3.5 7.3 7.1 6.9 6.4 7.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 CBY43186.1 - 4.6 7.4 9.1 8.4 6.6 0.0 2.7 2 1 0 2 2 2 0 PHD-zinc-finger like domain RRM_1 PF00076.22 CBY43188.1 - 0.00087 19.1 0.2 0.28 11.0 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CBY43188.1 - 0.0032 17.7 0.7 0.31 11.2 0.0 2.5 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter adh_short PF00106.25 CBY43189.1 - 1.2e-10 41.2 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY43189.1 - 6.2e-08 32.5 0.0 8.7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CBY43189.1 - 0.00038 20.1 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 CBY43189.1 - 0.00057 19.9 0.0 0.00083 19.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Imp-YgjV PF10688.9 CBY43189.1 - 0.027 14.3 0.5 0.042 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial inner membrane protein Glyco_trans_4_5 PF16994.5 CBY43189.1 - 0.063 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Spore_SspJ PF09575.10 CBY43189.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) TrkA_N PF02254.18 CBY43189.1 - 0.16 12.2 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Syntaxin-18_N PF10496.9 CBY43190.1 - 0.084 13.1 0.2 0.094 13.0 0.2 1.2 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus fn3 PF00041.21 CBY43192.1 - 1.2e-34 118.5 0.0 7.8e-13 48.6 0.0 3.7 3 0 0 3 3 3 3 Fibronectin type III domain I-set PF07679.16 CBY43192.1 - 2.6e-14 53.0 0.5 6.6e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY43192.1 - 2.5e-06 28.0 0.1 0.00046 20.7 0.0 3.1 3 0 0 3 3 3 1 Immunoglobulin domain Pur_ac_phosph_N PF16656.5 CBY43192.1 - 3e-05 24.5 0.3 0.023 15.3 0.0 3.7 4 1 0 4 4 4 1 Purple acid Phosphatase, N-terminal domain Ig_2 PF13895.6 CBY43192.1 - 0.0003 21.1 0.1 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 1 Immunoglobulin domain ig PF00047.25 CBY43192.1 - 0.016 15.4 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin domain Invasin_D3 PF09134.10 CBY43192.1 - 0.027 14.8 1.0 0.12 12.7 0.1 2.5 2 1 0 2 2 2 0 Invasin, domain 3 V-set PF07686.17 CBY43192.1 - 0.045 13.9 0.1 1.8 8.8 0.0 2.7 2 1 0 2 2 2 0 Immunoglobulin V-set domain Ig_5 PF16681.5 CBY43192.1 - 0.23 11.9 1.6 2.2 8.7 0.1 3.0 2 1 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain 7tm_1 PF00001.21 CBY43193.1 - 3e-11 43.1 6.7 3.8e-10 39.6 6.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srw PF10324.9 CBY43193.1 - 0.0046 16.3 4.7 0.0052 16.1 4.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw 7TM_GPCR_Srx PF10328.9 CBY43193.1 - 0.025 14.2 5.4 0.075 12.7 2.9 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx GPHH PF16905.5 CBY43195.1 - 4.3e-07 29.6 0.0 9.6e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated IQ PF00612.27 CBY43195.1 - 0.11 12.3 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF3136 PF11334.8 CBY43196.1 - 0.014 15.1 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) PDZ PF00595.24 CBY43197.1 - 0.024 15.0 0.0 0.086 13.2 0.0 1.9 2 0 0 2 2 2 0 PDZ domain GRIP PF01465.20 CBY43198.1 - 1.6e-10 40.7 0.0 5.1e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 GRIP domain TPR_MLP1_2 PF07926.12 CBY43198.1 - 0.0035 17.4 20.0 0.0035 17.4 20.0 3.5 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 CBY43198.1 - 0.037 11.6 45.9 0.19 9.2 45.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Cytochrom_NNT PF03264.14 CBY43198.1 - 0.67 9.6 4.7 1.8 8.3 4.7 1.7 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Flagellin_N PF00669.20 CBY43198.1 - 1 9.4 14.9 0.55 10.3 2.2 3.4 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Fib_alpha PF08702.10 CBY43198.1 - 1.1 9.5 33.6 0.22 11.7 7.6 3.8 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 CBY43198.1 - 3.5 5.4 34.8 1.2 7.0 14.7 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family UPF0184 PF03670.13 CBY43198.1 - 4.2 7.8 16.8 2.1 8.8 1.5 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Vip3A_N PF12495.8 CBY43198.1 - 7 6.5 11.3 7.3 6.5 2.5 2.6 1 1 2 3 3 3 0 Vegetative insecticide protein 3A N terminal Sec34 PF04136.15 CBY43198.1 - 8.8 6.2 34.5 0.059 13.2 5.5 4.2 1 1 3 4 4 4 0 Sec34-like family EF-hand_6 PF13405.6 CBY43199.1 - 3.8e-05 23.3 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CBY43199.1 - 4.5e-05 22.7 0.0 6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CBY43199.1 - 0.0002 20.7 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY43199.1 - 0.0011 19.3 0.0 0.0013 19.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair Kelch_4 PF13418.6 CBY43200.1 - 6.7e-08 32.4 0.4 0.082 12.9 0.0 4.5 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY43200.1 - 1.2e-06 28.3 0.8 0.94 9.5 0.2 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBY43200.1 - 2.7e-05 23.6 2.4 0.25 10.9 0.1 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CBY43200.1 - 4.2e-05 23.4 0.4 0.96 9.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CBY43200.1 - 0.00013 22.2 0.0 0.018 15.3 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 CBY43200.1 - 0.00021 21.5 0.0 1.9 8.9 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF5442 PF17514.2 CBY43201.1 - 0.00049 20.2 1.8 0.76 10.0 0.8 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5442) Bcl-2 PF00452.19 CBY43201.1 - 0.00071 20.2 0.2 0.0036 18.0 0.1 2.1 1 1 1 2 2 2 1 Apoptosis regulator proteins, Bcl-2 family DUF3320 PF11784.8 CBY43201.1 - 0.031 14.2 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) Ku_PK_bind PF08785.11 CBY43201.1 - 0.073 13.2 0.5 4.7 7.4 0.2 2.4 2 0 0 2 2 2 0 Ku C terminal domain like ORF6N PF10543.9 CBY43201.1 - 0.37 11.0 2.9 6.5 7.0 0.4 3.2 2 1 2 4 4 4 0 ORF6N domain RNase_J_C PF17770.1 CBY43201.1 - 0.67 11.0 2.4 8.9 7.4 0.2 3.1 2 1 0 3 3 3 0 Ribonuclease J C-terminal domain NAD_binding_2 PF03446.15 CBY43202.1 - 2.1e-35 122.2 0.6 2.4e-35 122.0 0.6 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CBY43202.1 - 9.9e-05 22.9 0.0 0.00016 22.2 0.0 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CBY43202.1 - 0.00018 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CBY43202.1 - 0.0017 18.6 0.1 0.09 13.0 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CBY43202.1 - 0.062 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4031 PF13223.6 CBY43202.1 - 0.091 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) RcpB PF16971.5 CBY43204.1 - 0.002 18.1 0.7 0.003 17.5 0.7 1.2 1 0 0 1 1 1 1 Rough colony protein B, tight adherence - tad - subunit GTP-bdg_M PF16360.5 CBY43204.1 - 0.092 13.4 2.3 0.21 12.2 2.3 1.6 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region TMPIT PF07851.13 CBY43204.1 - 0.85 8.8 5.4 1.1 8.4 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein PAP_assoc PF03828.19 CBY43207.1 - 5.2e-14 52.2 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase RT_RNaseH_2 PF17919.1 CBY43208.1 - 1e-24 86.5 0.0 2.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CBY43208.1 - 1.5e-14 54.1 0.0 3.4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CBY43208.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Lactamase_B_6 PF16661.5 CBY43208.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBY43208.1 - 0.12 12.3 0.5 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Metallophos PF00149.28 CBY43209.1 - 3.1e-14 54.0 0.8 4.9e-14 53.3 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBY43209.1 - 0.003 17.8 0.1 0.0069 16.6 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Chromo PF00385.24 CBY43210.1 - 3.9e-14 52.3 0.7 8e-14 51.3 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Gln_deamidase_2 PF18626.1 CBY43210.1 - 0.053 13.8 0.2 0.15 12.3 0.2 1.8 1 1 0 1 1 1 0 Glutaminase Sod_Fe_C PF02777.18 CBY43211.1 - 1.5e-34 118.2 0.1 1.8e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBY43211.1 - 1.7e-05 25.2 0.0 3.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Iso_dh PF00180.20 CBY43212.1 - 0.0066 15.6 0.1 0.0069 15.6 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_transf_64 PF09258.10 CBY43213.1 - 2.3e-40 138.5 0.2 2.8e-40 138.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Cloacin_immun PF03513.14 CBY43215.1 - 0.067 13.5 0.1 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Cloacin immunity protein zf-GRF PF06839.12 CBY43216.1 - 2.7e-11 43.4 9.0 2.7e-11 43.4 9.0 3.1 4 0 0 4 4 4 1 GRF zinc finger zf-CCHC PF00098.23 CBY43216.1 - 0.086 12.9 4.9 0.26 11.4 4.9 1.9 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_23 PF13489.6 CBY43217.1 - 3e-16 59.7 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY43217.1 - 4e-11 43.5 0.0 1.8e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY43217.1 - 1.1e-10 42.0 0.2 7.7e-09 36.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBY43217.1 - 2.4e-07 30.7 0.1 9.2e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY43217.1 - 2.7e-07 31.2 0.1 2.2e-05 25.0 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBY43217.1 - 0.0071 15.8 0.0 0.76 9.2 0.0 2.3 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_28 PF02636.17 CBY43217.1 - 0.013 15.1 0.2 0.11 12.1 0.0 2.3 2 1 1 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CheR PF01739.18 CBY43217.1 - 0.023 14.2 0.0 0.59 9.6 0.0 2.4 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Peptidase_M3_N PF08439.10 CBY43217.1 - 0.067 13.5 0.9 1.9 8.8 0.3 2.6 3 0 0 3 3 3 0 Oligopeptidase F NNMT_PNMT_TEMT PF01234.17 CBY43217.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family RrnaAD PF00398.20 CBY43217.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HlyD_D4 PF16572.5 CBY43217.1 - 0.15 11.9 0.4 0.28 11.1 0.4 1.4 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB NUDIX PF00293.28 CBY43218.1 - 7.1e-13 48.7 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain TMC PF07810.13 CBY43220.1 - 7.5e-26 90.9 1.2 7.5e-26 90.9 1.2 1.6 2 0 0 2 2 2 1 TMC domain FA_desaturase PF00487.24 CBY43220.1 - 0.059 13.2 4.0 0.082 12.7 3.3 1.6 1 1 0 1 1 1 0 Fatty acid desaturase Peptidase_M48_N PF16491.5 CBY43222.1 - 5.5e-53 179.6 12.1 5.5e-53 179.6 12.1 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CBY43222.1 - 1.7e-43 148.7 0.0 2.4e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 TEX13 PF15186.6 CBY43225.1 - 0.042 13.5 1.8 0.082 12.6 0.1 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family PAN_3 PF08277.12 CBY43227.1 - 0.0005 19.8 13.7 0.027 14.3 2.6 3.1 3 0 0 3 3 3 2 PAN-like domain PAN_1 PF00024.26 CBY43227.1 - 0.0016 18.3 14.3 0.057 13.4 4.4 3.0 3 0 0 3 3 3 2 PAN domain Gal_Lectin PF02140.18 CBY43228.1 - 1.7e-06 28.4 0.1 3.1e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Galactose binding lectin domain STI1 PF17830.1 CBY43229.1 - 0.041 13.8 1.0 0.13 12.2 0.1 2.5 2 1 0 2 2 2 0 STI1 domain Met_synt_B12 PF02965.17 CBY43229.1 - 0.081 12.4 3.4 0.033 13.7 1.0 1.5 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Nif11 PF07862.11 CBY43229.1 - 0.29 11.5 5.4 0.24 11.7 0.7 3.0 2 0 0 2 2 2 0 Nif11 domain Lipase_GDSL_2 PF13472.6 CBY43229.1 - 0.82 10.0 3.7 0.78 10.1 0.3 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family EnY2 PF10163.9 CBY43229.1 - 2.1 8.8 7.1 0.31 11.4 1.8 2.4 2 1 1 3 3 3 0 Transcription factor e(y)2 Rsbr_N PF08678.10 CBY43229.1 - 4.7 7.3 6.4 24 5.0 0.0 2.6 3 0 0 3 3 3 0 Rsbr N terminal DUF1090 PF06476.12 CBY43229.1 - 7.4 6.7 19.4 0.19 11.9 5.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) PP2C PF00481.21 CBY43230.1 - 1.2e-47 162.7 0.1 1.4e-47 162.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 CBY43231.1 - 4.1e-64 216.5 0.0 5e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43231.1 - 2.2e-36 125.5 0.0 2.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY43231.1 - 2.4e-08 33.7 0.0 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBY43231.1 - 8e-07 28.3 0.0 1.4e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBY43231.1 - 0.00026 21.0 0.1 0.0031 17.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBY43231.1 - 0.00083 18.2 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBY43231.1 - 0.0073 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CBY43231.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBY43231.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 P66_CC PF16563.5 CBY43232.1 - 6.7e-07 28.8 1.2 6.7e-07 28.8 1.2 1.8 2 0 0 2 2 2 1 Coiled-coil and interaction region of P66A and P66B with MBD2 LXG PF04740.12 CBY43232.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.8 2 0 0 2 2 2 0 LXG domain of WXG superfamily YlqD PF11068.8 CBY43232.1 - 0.021 15.2 0.2 0.021 15.2 0.2 2.1 2 0 0 2 2 2 0 YlqD protein Goodbye PF17109.5 CBY43232.1 - 0.37 11.2 0.1 0.37 11.2 0.1 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Tristanin_u2 PF16638.5 CBY43232.1 - 3.5 8.5 7.3 0.43 11.4 0.9 2.2 2 1 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers FAM199X PF15814.5 CBY43232.1 - 9.1 5.2 10.3 13 4.8 10.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Trypsin PF00089.26 CBY43233.1 - 5e-32 111.5 0.3 2.3e-16 60.3 0.1 2.1 2 0 0 2 2 2 2 Trypsin TSP_1 PF00090.19 CBY43233.1 - 1.7e-07 31.3 8.6 1.7e-07 31.3 8.6 2.1 2 0 0 2 2 2 1 Thrombospondin type 1 domain DUF1986 PF09342.11 CBY43233.1 - 0.00065 20.1 0.0 0.19 12.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1986) Antimicrobial_6 PF08036.11 CBY43233.1 - 0.4 10.8 4.4 1.8 8.7 4.4 2.2 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide Mucin PF01456.17 CBY43239.1 - 0.13 12.3 26.3 0.24 11.4 26.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein XRCC4 PF06632.12 CBY43239.1 - 0.41 9.5 16.8 0.012 14.4 9.3 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Wbp11 PF09429.10 CBY43239.1 - 1.1 9.7 15.3 6.8 7.2 5.9 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 adh_short PF00106.25 CBY43240.1 - 5.8e-23 81.4 0.7 6.2e-23 81.3 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY43240.1 - 2.2e-17 63.4 0.3 2.5e-17 63.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY43240.1 - 7.5e-08 32.5 0.1 8.2e-08 32.4 0.1 1.0 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBY43240.1 - 0.011 15.7 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CBY43240.1 - 0.057 13.4 0.5 0.068 13.2 0.5 1.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PA PF02225.22 CBY43240.1 - 0.065 13.3 0.6 0.15 12.1 0.5 1.7 1 1 0 1 1 1 0 PA domain Band_7 PF01145.25 CBY43241.1 - 7.4e-33 114.0 0.3 9.2e-33 113.7 0.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBY43241.1 - 0.0059 16.3 0.1 0.0085 15.8 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family TFA2_Winged_2 PF18121.1 CBY43242.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.4 1 1 0 2 2 2 0 TFA2 Winged helix domain 2 DUF3928 PF13065.6 CBY43243.1 - 0.018 15.8 0.0 0.82 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3928) ArfGap PF01412.18 CBY43244.1 - 1e-31 109.4 3.2 2.7e-31 108.0 3.2 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Alpha_kinase PF02816.18 CBY43245.1 - 2.5e-53 180.9 0.1 4e-53 180.3 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_M24 PF00557.24 CBY43249.1 - 2.5e-08 33.9 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 CBY43250.1 - 1.7e-17 63.8 0.0 2.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBY43250.1 - 0.0062 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain zf-C3HC4_3 PF13920.6 CBY43251.1 - 2e-09 37.2 10.6 4e-09 36.2 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY43251.1 - 8.4e-09 35.6 11.4 2.1e-08 34.3 11.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CBY43251.1 - 2.6e-08 33.6 11.7 2.6e-08 33.6 11.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY43251.1 - 4.7e-08 32.9 11.8 1.1e-07 31.7 11.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBY43251.1 - 4.7e-07 29.5 9.7 1e-06 28.5 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY43251.1 - 9.5e-05 22.1 9.7 0.0002 21.1 9.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CBY43251.1 - 0.00013 21.9 7.4 0.00013 21.9 7.4 1.9 2 0 0 2 2 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CBY43251.1 - 0.00023 21.0 6.8 0.00053 19.8 6.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CBY43251.1 - 0.0015 18.6 5.6 0.0015 18.6 5.6 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY43251.1 - 0.0021 18.3 9.0 0.0021 18.3 9.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBY43251.1 - 0.0032 17.2 6.1 0.0032 17.2 6.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger GCD14 PF08704.10 CBY43251.1 - 0.0055 16.4 2.7 0.01 15.5 2.7 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit zf-ANAPC11 PF12861.7 CBY43251.1 - 0.57 10.3 8.7 0.25 11.4 5.5 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.16 CBY43251.1 - 1.1 9.5 13.4 3.3 8.0 13.1 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger zf-P11 PF03854.14 CBY43251.1 - 1.2 8.9 10.1 7 6.4 10.1 2.2 1 1 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 CBY43251.1 - 4.4 7.4 8.3 15 5.7 8.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 CBY43251.1 - 4.8 7.4 13.1 60 3.9 13.2 2.4 1 1 1 2 2 2 0 FYVE zinc finger Casc1_N PF15927.5 CBY43252.1 - 0.32 10.6 8.5 0.4 10.3 8.5 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus RNA_pol_Rpb1_3 PF04983.18 CBY43254.1 - 4.3e-47 160.0 0.0 8.1e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBY43254.1 - 1.8e-34 117.9 0.1 4.1e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 CBY43254.1 - 3.1e-31 108.8 0.1 7.3e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBY43254.1 - 7e-24 84.9 0.1 1.5e-23 83.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CBY43254.1 - 7.4e-05 22.7 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 Arm PF00514.23 CBY43255.1 - 1.5e-53 177.3 14.7 1.8e-08 34.2 0.2 7.5 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBY43255.1 - 4.5e-21 74.2 0.9 1.8e-20 72.2 1.3 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CBY43255.1 - 2.8e-12 46.9 1.4 0.051 14.1 0.0 5.5 3 1 3 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.6 CBY43255.1 - 5.7e-06 26.6 0.2 0.22 11.9 0.1 4.6 3 1 4 7 7 7 4 HEAT repeats Adaptin_N PF01602.20 CBY43255.1 - 0.00014 20.6 0.0 0.00041 19.0 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 CBY43255.1 - 0.00081 19.4 1.8 21 5.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_C PF11698.8 CBY43255.1 - 0.0017 18.4 0.2 1.9 8.6 0.0 2.6 2 1 0 2 2 2 2 V-ATPase subunit H RTP1_C1 PF10363.9 CBY43255.1 - 0.091 13.0 0.0 10 6.3 0.0 2.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 BACK PF07707.15 CBY43257.1 - 4.2e-08 33.2 0.2 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 CBY43257.1 - 1.1e-07 32.1 0.2 5.6e-07 29.8 0.1 2.3 2 1 0 2 2 2 1 BTB/POZ domain Phage_T4_Ndd PF06591.11 CBY43260.1 - 0.0021 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 T4-like phage nuclear disruption protein (Ndd) eIF-3c_N PF05470.12 CBY43262.1 - 1.3e-95 320.9 39.3 1.3e-76 258.3 30.4 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HBB PF06777.11 CBY43262.1 - 0.018 14.7 0.1 0.06 13.0 0.1 1.9 1 0 0 1 1 1 0 Helical and beta-bridge domain Sigma70_ner PF04546.13 CBY43263.1 - 0.023 14.6 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_Rpc82 PF05645.13 CBY43263.1 - 0.039 13.7 0.3 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Zona_pellucida PF00100.23 CBY43264.1 - 5.4e-06 26.4 0.0 6.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Zona pellucida-like domain DEAD PF00270.29 CBY43265.1 - 4.6e-33 114.5 0.0 8e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBY43265.1 - 1.9e-30 105.5 0.0 6.8e-30 103.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain EIIA-man PF03610.16 CBY43265.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 PTS system fructose IIA component ERCC3_RAD25_C PF16203.5 CBY43265.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF5129 PF17173.4 CBY43266.1 - 0.058 12.5 0.2 0.29 10.2 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5129) Guanylate_kin PF00625.21 CBY43267.1 - 1.4e-42 145.5 0.6 1.4e-42 145.5 0.6 1.6 2 0 0 2 2 2 1 Guanylate kinase SUFU_C PF12470.8 CBY43267.1 - 0.051 13.6 0.3 0.074 13.1 0.3 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Peptidase_S49_N PF08496.10 CBY43267.1 - 5.3 7.1 7.8 12 5.9 7.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EF-hand_6 PF13405.6 CBY43269.1 - 2.5e-12 45.6 0.5 9e-07 28.3 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY43269.1 - 9.9e-12 43.5 1.9 3e-06 26.4 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBY43269.1 - 6.5e-09 34.9 2.7 9.1e-06 24.9 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBY43269.1 - 7.7e-09 35.3 0.4 0.003 17.4 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 CBY43269.1 - 1.6e-08 34.9 0.5 7.5e-08 32.7 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair TRCF PF03461.15 CBY43269.1 - 0.018 15.4 0.1 0.024 15.0 0.1 1.2 1 0 0 1 1 1 0 TRCF domain SPARC_Ca_bdg PF10591.9 CBY43269.1 - 0.068 13.5 0.1 0.084 13.2 0.1 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Zona_pellucida PF00100.23 CBY43270.1 - 1.5e-10 41.4 0.9 1.5e-10 41.3 0.9 1.0 1 0 0 1 1 1 1 Zona pellucida-like domain FXa_inhibition PF14670.6 CBY43271.1 - 2.2 8.6 12.1 9.8 6.6 12.1 2.2 1 1 0 1 1 1 0 Coagulation Factor Xa inhibitory site Rab_eff_C PF04698.12 CBY43274.1 - 0.013 13.9 0.2 0.014 13.7 0.2 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DnaJ PF00226.31 CBY43275.1 - 2.4e-05 24.4 5.5 0.0092 16.1 0.7 2.7 2 1 1 3 3 3 2 DnaJ domain DUF4482 PF14818.6 CBY43275.1 - 0.008 17.1 7.1 0.0096 16.8 7.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) DUF2524 PF10732.9 CBY43275.1 - 0.057 13.7 2.3 0.073 13.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) TMPIT PF07851.13 CBY43275.1 - 8.6 5.5 6.1 10 5.2 6.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein TUDOR PF00567.24 CBY43277.1 - 5e-23 81.4 0.1 1.5e-11 44.4 0.0 2.6 2 0 0 2 2 2 2 Tudor domain SMN PF06003.12 CBY43277.1 - 6e-07 29.0 3.7 0.00017 20.9 0.0 3.3 3 0 0 3 3 3 2 Survival motor neuron protein (SMN) DUF4537 PF15057.6 CBY43277.1 - 0.00011 22.2 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4537) PCB_OB PF17092.5 CBY43277.1 - 0.0018 19.0 0.0 1.3 9.8 0.0 2.6 2 0 0 2 2 2 2 Penicillin-binding protein OB-like domain SAWADEE PF16719.5 CBY43277.1 - 0.007 16.4 1.3 3.2 7.7 0.1 2.6 2 0 0 2 2 2 2 SAWADEE domain GH97_C PF14509.6 CBY43277.1 - 0.14 12.4 0.1 31 4.9 0.0 2.8 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation SH3_9 PF14604.6 CBY43277.1 - 0.18 11.7 0.4 7.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Variant SH3 domain Zip PF02535.22 CBY43279.1 - 0.039 13.2 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CBY43279.1 - 0.045 12.5 1.4 0.056 12.2 1.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.12 CBY43279.1 - 0.4 9.2 17.3 0.59 8.6 17.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CBY43279.1 - 1.7 6.9 8.3 2.3 6.4 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.12 CBY43279.1 - 1.7 6.5 3.8 2.2 6.2 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.8 CBY43279.1 - 2.3 6.9 7.0 4.2 6.0 7.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sushi PF00084.20 CBY43281.1 - 5.9e-34 116.5 51.8 4.4e-09 36.8 5.3 6.4 6 0 0 6 6 6 6 Sushi repeat (SCR repeat) Cupin_8 PF13621.6 CBY43282.1 - 7.3e-32 111.1 0.0 9.7e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CBY43282.1 - 6.6e-06 25.8 0.0 3.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 CBY43282.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Cupin JmjC PF02373.22 CBY43282.1 - 0.087 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Zip PF02535.22 CBY43284.1 - 2.1 7.5 7.1 2.3 7.4 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Asp-B-Hydro_N PF05279.11 CBY43284.1 - 4.5 7.3 11.7 6.1 6.8 11.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.15 CBY43284.1 - 5.9 5.6 12.1 5.9 5.5 12.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 CBY43284.1 - 8.1 5.4 17.3 9.1 5.2 17.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) VEFS-Box PF09733.9 CBY43285.1 - 0.0077 16.1 0.4 0.015 15.1 0.2 1.6 1 1 1 2 2 2 1 VEFS-Box of polycomb protein DUF5347 PF17282.2 CBY43285.1 - 0.11 12.8 4.8 1.1 9.6 2.5 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5347) Atg14 PF10186.9 CBY43285.1 - 0.24 10.4 11.3 0.27 10.3 11.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RF-1 PF00472.20 CBY43285.1 - 2 8.4 8.4 1.9 8.4 7.3 1.6 1 1 1 2 2 2 0 RF-1 domain UPF0242 PF06785.11 CBY43285.1 - 2.5 8.2 14.8 2.9 8.0 13.9 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 CBY43285.1 - 3.3 6.9 9.7 3.7 6.7 9.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 CBY43285.1 - 4.7 7.9 9.1 12 6.5 9.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA ASH PF15780.5 CBY43286.1 - 3.5e-08 33.5 5.3 0.0022 18.2 0.1 4.4 3 1 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Gmad2 PF10648.9 CBY43286.1 - 0.0049 17.1 0.1 2.8 8.2 0.0 3.0 3 0 0 3 3 3 2 Immunoglobulin-like domain of bacterial spore germination TMEM131_like PF12371.8 CBY43286.1 - 0.0091 16.2 1.4 1.7 8.9 0.0 3.3 3 0 0 3 3 3 2 Transmembrane protein 131-like Cys_rich_FGFR PF00839.17 CBY43288.1 - 1.5e-89 294.1 63.1 1.4e-12 47.5 1.2 10.2 10 0 0 10 10 10 10 Cysteine rich repeat Pkinase PF00069.25 CBY43289.1 - 7.2e-76 255.0 0.0 8.2e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43289.1 - 1.6e-37 129.2 0.0 2e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY43289.1 - 1.9e-07 30.7 0.1 0.00023 20.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBY43289.1 - 0.0003 20.2 0.4 0.0034 16.7 0.0 2.1 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY43289.1 - 0.00082 19.4 0.0 0.64 9.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBY43289.1 - 0.028 14.0 1.3 0.27 10.8 1.3 2.0 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBY43290.1 - 8.8e-05 22.0 0.0 9.1e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain WW_1 PF18507.1 CBY43290.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 WW domain PRMT5_C PF17286.2 CBY43291.1 - 1.2e-05 25.2 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain La PF05383.17 CBY43292.1 - 2.5e-19 69.1 0.1 4.9e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBY43292.1 - 2.8e-12 46.3 0.1 5.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CBY43292.1 - 0.052 13.8 1.5 0.15 12.3 1.4 2.1 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter zf-H2C2_2 PF13465.6 CBY43293.1 - 2.3e-12 46.7 19.6 2.5e-08 34.0 0.3 4.2 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 CBY43293.1 - 5e-12 45.6 18.3 2.9e-05 24.3 1.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY43293.1 - 3.8e-09 36.6 16.1 0.00061 20.4 0.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CBY43293.1 - 4.2e-07 29.8 9.3 0.00016 21.6 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CBY43293.1 - 0.003 17.9 11.5 0.21 12.0 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBY43293.1 - 0.01 16.1 6.7 1 9.7 0.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBY43293.1 - 0.016 15.5 10.6 0.27 11.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CBY43293.1 - 0.026 15.0 4.8 1.8 9.1 0.0 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 CBY43293.1 - 0.033 14.3 3.6 2.4 8.4 1.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CBY43293.1 - 0.043 14.2 8.7 2.7 8.4 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) ZZ PF00569.17 CBY43293.1 - 0.23 11.3 5.4 21 5.0 0.3 3.5 4 0 0 4 4 4 0 Zinc finger, ZZ type CpXC PF14353.6 CBY43293.1 - 0.63 10.1 3.8 4.4 7.4 3.8 2.3 1 1 0 1 1 1 0 CpXC protein Rpr2 PF04032.16 CBY43293.1 - 0.68 10.2 4.2 7.4 6.9 4.2 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_recom PF13408.6 CBY43293.1 - 0.74 10.4 6.5 9.7 6.8 0.1 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-H2C2_5 PF13909.6 CBY43293.1 - 1 9.2 13.6 2.7 7.8 1.0 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain C1_2 PF03107.16 CBY43293.1 - 2 8.8 8.8 16 5.9 4.0 3.1 1 1 1 2 2 2 0 C1 domain zf_C2H2_ZHX PF18387.1 CBY43293.1 - 2.3 7.9 8.3 12 5.6 0.2 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-HIT PF04438.16 CBY43293.1 - 7.7 6.5 7.8 3.9 7.4 0.3 2.7 3 0 0 3 3 3 0 HIT zinc finger zf-BED PF02892.15 CBY43293.1 - 8.5 6.5 12.2 5.9 7.0 2.0 3.1 1 1 2 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 CBY43293.1 - 8.6 6.4 9.6 2.8 8.0 2.4 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C4 PF00105.18 CBY43294.1 - 1e-31 109.2 18.3 1.7e-31 108.5 18.3 1.4 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Hormone_recep PF00104.30 CBY43294.1 - 3.4e-13 49.6 0.1 1.7e-12 47.3 0.1 2.0 1 1 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor MFS_1 PF07690.16 CBY43295.1 - 3.1e-31 108.6 11.6 4.1e-31 108.2 11.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Dynein_C PF18199.1 CBY43296.1 - 1.1e-112 376.3 0.0 1.3e-112 376.0 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBY43296.1 - 3.2e-30 105.1 0.0 5.2e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Spo7_2_N PF15407.6 CBY43296.1 - 0.025 14.2 0.0 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein family 7 Kelch_1 PF01344.25 CBY43297.1 - 1.8e-23 81.9 2.3 1e-07 31.4 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CBY43297.1 - 8.9e-22 76.6 1.1 4.1e-05 23.7 0.0 4.2 3 1 1 4 4 4 4 Kelch motif Kelch_4 PF13418.6 CBY43297.1 - 3e-16 59.2 1.0 1.6e-08 34.4 0.0 4.3 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY43297.1 - 3.3e-15 55.7 4.8 4.3e-05 23.4 0.2 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 CBY43297.1 - 3.3e-12 46.4 0.1 0.0054 17.0 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY43297.1 - 6.6e-09 35.4 5.1 0.018 15.0 0.0 4.0 3 1 0 3 3 3 3 Kelch motif zf-CCHC PF00098.23 CBY43298.1 - 1.3e-12 47.2 26.3 9.7e-05 22.3 2.9 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CBY43298.1 - 0.026 14.5 21.1 0.046 13.7 4.1 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 CBY43298.1 - 1.7 8.4 19.5 2.1 8.1 2.3 3.9 3 1 1 4 4 4 0 Zinc knuckle DUF919 PF06034.11 CBY43298.1 - 4.4 7.2 10.8 10 6.0 0.5 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) zf-CCHC_5 PF14787.6 CBY43298.1 - 6 6.7 26.0 2.2 8.1 4.0 3.8 3 1 0 3 3 3 0 GAG-polyprotein viral zinc-finger TraG-D_C PF12696.7 CBY43299.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Curto_V2 PF07325.11 CBY43299.1 - 0.069 13.0 3.4 0.21 11.5 1.6 2.4 1 1 1 2 2 2 0 Curtovirus V2 protein Inhibitor_I29 PF08246.12 CBY43299.1 - 0.16 12.4 0.9 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) SET PF00856.28 CBY43300.1 - 5.7e-08 33.3 0.4 7.1e-08 33.0 0.4 1.3 1 0 0 1 1 1 1 SET domain ERG2_Sigma1R PF04622.12 CBY43300.1 - 0.14 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein CREPT PF16566.5 CBY43302.1 - 0.0011 19.2 1.7 0.0012 19.0 1.7 1.2 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF5401 PF17380.2 CBY43302.1 - 0.044 11.9 5.8 0.045 11.8 5.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SesA PF17107.5 CBY43302.1 - 0.084 13.1 3.8 0.11 12.6 3.8 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RRM_1 PF00076.22 CBY43303.1 - 5.8e-85 279.1 1.2 9.4e-22 76.6 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBY43303.1 - 9.6e-11 41.5 0.0 0.03 14.3 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CBY43303.1 - 5.3e-09 36.0 0.1 0.24 11.4 0.0 4.4 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CBY43303.1 - 1.4e-08 34.6 0.4 0.37 10.9 0.0 4.3 4 0 0 4 4 4 2 Limkain b1 RRM_7 PF16367.5 CBY43303.1 - 4.1e-07 30.0 0.3 2.2 8.5 0.0 5.4 4 3 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 CBY43303.1 - 3.5e-05 23.6 0.0 0.061 13.2 0.0 3.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif PABP PF00658.18 CBY43303.1 - 0.00021 21.4 0.1 0.01 16.0 0.1 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RNA_bind PF08675.11 CBY43303.1 - 0.011 15.7 0.1 0.18 11.8 0.0 3.1 4 1 0 4 4 4 0 RNA binding domain SET_assoc PF11767.8 CBY43303.1 - 0.012 15.2 1.7 7.9 6.2 0.0 4.2 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated DHHA1 PF02272.19 CBY43303.1 - 0.1 13.0 0.1 0.81 10.1 0.1 2.4 2 0 0 2 2 2 0 DHHA1 domain NYN PF01936.18 CBY43303.1 - 0.16 12.4 0.0 17 5.9 0.0 3.0 3 1 1 4 4 4 0 NYN domain Kelch_5 PF13854.6 CBY43304.1 - 0.064 13.3 2.5 0.22 11.6 0.0 2.9 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 CBY43304.1 - 0.15 12.1 3.6 3 8.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif DMAP1 PF05499.12 CBY43305.1 - 7.6e-26 91.0 2.2 1.8e-25 89.7 2.2 1.6 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like PF16282.5 CBY43305.1 - 1.2e-18 67.0 0.5 2.7e-18 65.9 0.5 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ntox1 PF15500.6 CBY43305.1 - 0.0099 16.2 1.4 0.02 15.2 1.4 1.5 1 0 0 1 1 1 1 Putative RNase-like toxin, toxin_1 zf-CCCH PF00642.24 CBY43306.1 - 7.1e-09 35.4 11.1 0.00022 21.0 2.3 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBY43306.1 - 7.4e-05 22.4 14.2 0.012 15.4 3.7 3.0 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBY43306.1 - 0.11 12.6 18.4 3.2 7.9 0.4 3.9 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 CBY43306.1 - 1.1 9.8 13.3 9.2 6.9 3.2 4.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Mucin2_WxxW PF13330.6 CBY43308.1 - 2e-13 50.9 7.2 3.5e-11 43.8 0.2 3.4 3 0 0 3 3 3 2 Mucin-2 protein WxxW repeating region Pro_isomerase PF00160.21 CBY43312.1 - 1.1e-24 87.5 0.3 2.1e-24 86.6 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CBY43312.1 - 2.2e-09 36.7 10.9 0.00058 19.8 0.2 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBY43312.1 - 1.2e-05 25.0 6.2 0.12 12.2 1.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBY43312.1 - 3.1e-05 23.8 6.3 0.044 14.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY43312.1 - 3.3e-05 24.4 4.0 0.001 19.7 2.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBY43312.1 - 7.3e-05 23.2 3.1 7.3e-05 23.2 3.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBY43312.1 - 8.6e-05 22.7 0.1 0.00023 21.3 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBY43312.1 - 0.00011 22.8 3.0 0.0028 18.3 0.7 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Nop14 PF04147.12 CBY43312.1 - 0.003 15.9 3.7 0.003 15.9 3.7 2.0 1 1 1 2 2 2 1 Nop14-like family TPR_20 PF14561.6 CBY43312.1 - 0.0045 17.3 1.5 0.016 15.5 1.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBY43312.1 - 0.0064 16.8 3.1 10 6.5 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBY43312.1 - 0.05 13.8 0.1 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.10 CBY43312.1 - 0.071 12.1 0.5 0.098 11.6 0.5 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CBY43312.1 - 0.18 12.5 6.8 3.2 8.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBY43312.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.6 3 1 1 4 4 3 0 TPR repeat ANAPC3 PF12895.7 CBY43312.1 - 1.2 9.4 5.0 0.27 11.5 1.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBY43312.1 - 3.8 7.7 11.7 0.11 12.6 1.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Phos_pyr_kin PF08543.12 CBY43313.1 - 4.7e-07 29.5 0.0 6.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aldolase_II PF00596.21 CBY43314.1 - 9e-10 38.8 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain EF-hand_1 PF00036.32 CBY43314.1 - 0.00019 20.7 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBY43314.1 - 0.00075 19.2 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CBY43314.1 - 0.0038 16.6 0.2 0.0057 16.1 0.2 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CBY43314.1 - 0.0064 16.9 0.0 0.01 16.3 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair Mt_ATP_synt PF15704.5 CBY43315.1 - 0.19 11.6 5.8 0.27 11.1 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit Kelch_6 PF13964.6 CBY43316.1 - 1.2e-28 98.4 0.5 5.8e-08 32.7 0.0 6.5 3 1 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CBY43316.1 - 3.4e-28 97.0 2.3 1.7e-09 37.1 0.0 6.0 6 2 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CBY43316.1 - 4.3e-21 74.6 0.9 2.1e-06 27.6 0.0 6.7 6 3 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY43316.1 - 7.8e-14 51.6 0.0 0.00089 19.5 0.0 6.2 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CBY43316.1 - 6.1e-10 38.7 0.6 0.022 14.7 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CBY43316.1 - 1.7e-09 37.4 0.1 0.012 15.6 0.0 6.0 6 1 0 6 6 6 2 Kelch motif BACK PF07707.15 CBY43318.1 - 1.2e-09 38.2 0.2 1.9e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 CBY43318.1 - 1.2e-06 28.7 0.1 4.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Toxin_13 PF07822.11 CBY43319.1 - 0.052 13.7 0.7 0.085 13.0 0.1 1.7 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein SPOC PF07744.13 CBY43321.1 - 8.9e-29 100.4 0.0 1.2e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 SPOC domain DUF3275 PF11679.8 CBY43327.1 - 5.6 6.9 7.3 8 6.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Tubulin PF00091.25 CBY43328.1 - 6.8e-68 228.8 0.0 8.9e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY43328.1 - 2e-47 160.5 0.0 3.3e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY43328.1 - 0.0018 18.0 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.27 CBY43329.1 - 4.2e-14 52.2 0.1 4.7e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Zip PF02535.22 CBY43330.1 - 1.8e-16 60.3 0.2 2e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3938 PF13074.6 CBY43330.1 - 0.021 15.1 0.2 0.055 13.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) YqzH PF14164.6 CBY43331.1 - 0.076 13.1 0.6 0.14 12.2 0.6 1.5 1 0 0 1 1 1 0 YqzH-like protein Macoilin PF09726.9 CBY43331.1 - 2.1 6.8 12.3 2 6.9 12.3 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_S30 PF01577.16 CBY43331.1 - 2.2 7.9 9.0 2.2 7.8 9.0 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease LRR_6 PF13516.6 CBY43332.1 - 1.5e-06 27.8 9.8 0.34 11.1 0.1 5.7 5 1 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CBY43332.1 - 0.00019 21.8 20.7 0.011 16.2 1.1 6.5 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CBY43332.1 - 0.021 14.7 0.3 0.09 12.7 0.1 2.3 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.6 CBY43332.1 - 3.1 7.6 12.2 0.42 10.4 2.7 4.2 2 2 2 4 4 4 0 Leucine rich repeat MOSC PF03473.17 CBY43333.1 - 2.3e-16 60.0 0.0 3.3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Kazal_2 PF07648.15 CBY43334.1 - 3e-39 132.9 34.8 3.4e-10 39.9 1.7 7.0 6 1 1 7 7 7 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 CBY43334.1 - 2.1e-38 130.1 31.1 1.5e-09 37.7 1.3 7.0 4 3 3 7 7 7 5 Kazal-type serine protease inhibitor domain zf-RING_2 PF13639.6 CBY43336.1 - 2.8e-09 37.1 8.9 3.6e-09 36.8 8.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY43336.1 - 5.9e-05 22.9 10.2 0.00011 22.0 10.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY43336.1 - 6.9e-05 22.6 10.6 0.00013 21.8 10.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY43336.1 - 0.00092 19.1 11.3 0.0012 18.7 11.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Rad50_zn_hook PF04423.14 CBY43336.1 - 0.0023 17.8 2.2 0.0049 16.7 2.2 1.6 1 0 0 1 1 1 1 Rad50 zinc hook motif zf-RING_4 PF14570.6 CBY43336.1 - 0.0027 17.5 9.2 0.0048 16.7 9.2 1.4 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.21 CBY43336.1 - 0.0042 17.2 9.6 0.011 15.8 4.3 2.1 1 1 1 2 2 2 1 FYVE zinc finger zf-rbx1 PF12678.7 CBY43336.1 - 0.0053 17.0 8.4 0.05 13.9 8.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 CBY43336.1 - 0.0064 16.1 7.2 0.021 14.5 7.2 1.8 1 1 0 1 1 1 1 P-11 zinc finger zf-C3HC4 PF00097.25 CBY43336.1 - 0.0087 15.9 11.3 0.014 15.3 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBY43336.1 - 0.014 15.2 8.2 0.097 12.5 7.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CBY43336.1 - 0.021 14.8 3.8 0.023 14.7 3.8 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF2321 PF10083.9 CBY43336.1 - 0.037 13.7 4.6 0.048 13.3 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Rtf2 PF04641.12 CBY43336.1 - 0.053 12.9 8.1 0.069 12.5 2.1 1.9 1 1 1 2 2 2 0 Rtf2 RING-finger zf-RING_UBOX PF13445.6 CBY43336.1 - 0.073 13.1 4.4 0.061 13.4 3.1 1.6 1 1 0 1 1 1 0 RING-type zinc-finger RecR PF02132.15 CBY43336.1 - 0.75 9.4 8.0 12 5.6 0.0 2.9 2 1 0 2 2 2 0 RecR protein DUF983 PF06170.12 CBY43336.1 - 1.4 9.4 0.1 1.4 9.4 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF983) zf-C3HC4_3 PF13920.6 CBY43337.1 - 0.00012 21.9 14.6 0.00012 21.9 14.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CBY43337.1 - 0.0017 18.5 13.7 0.0017 18.5 13.7 2.6 2 1 1 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 CBY43337.1 - 0.013 15.4 17.6 0.013 15.4 17.6 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBY43337.1 - 0.041 14.2 16.1 0.041 14.2 16.1 3.1 3 1 0 3 3 3 0 Ring finger domain zf_UBZ PF18439.1 CBY43337.1 - 0.31 10.6 0.1 0.31 10.6 0.1 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Ureidogly_lyase PF04115.12 CBY43337.1 - 0.32 10.8 5.5 1.9 8.2 5.5 2.1 1 1 0 1 1 1 0 Ureidoglycolate lyase zf-RING_6 PF14835.6 CBY43337.1 - 0.48 10.3 6.3 1.2 9.1 6.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBY43337.1 - 1 9.3 19.7 0.14 12.0 13.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ERM PF00769.19 CBY43337.1 - 3.2 7.5 42.4 5.3 6.8 2.3 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 CBY43338.1 - 0.00011 21.2 21.6 0.00015 20.8 21.6 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like zf-ACC PF17848.1 CBY43338.1 - 0.011 15.8 2.0 3.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Spc7 PF08317.11 CBY43338.1 - 0.23 10.3 31.7 0.19 10.6 0.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 CBY43338.1 - 2 7.4 26.0 3.6 6.6 26.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MCM3AP_GANP PF16769.5 CBY43338.1 - 2.1 6.5 19.7 2.5 6.2 19.7 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Jnk-SapK_ap_N PF09744.9 CBY43338.1 - 2.1 8.5 31.1 1.5 9.0 18.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 CBY43338.1 - 3.7 8.2 14.7 0.3 11.7 1.5 3.9 1 1 2 3 3 3 0 SlyX VRR_NUC PF08774.11 CBY43339.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_L11_N PF03946.14 CBY43340.1 - 1.7e-11 43.8 0.1 2.9e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain GHMP_kinases_C PF08544.13 CBY43342.1 - 3.4e-08 33.8 0.1 9.7e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Cnd1_N PF12922.7 CBY43342.1 - 0.049 13.5 0.2 0.063 13.1 0.2 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Pkinase PF00069.25 CBY43345.1 - 2.8e-20 72.8 0.0 3.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43345.1 - 1.3e-12 47.6 0.0 1.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 CBY43345.1 - 0.014 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 CBY43345.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase MFS_1 PF07690.16 CBY43348.1 - 1.9e-09 37.0 2.3 1.9e-09 37.0 2.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.6 CBY43348.1 - 0.033 14.5 1.1 0.45 10.8 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) MFS_1_like PF12832.7 CBY43348.1 - 0.11 11.3 1.6 0.18 10.6 0.1 2.0 2 1 1 3 3 3 0 MFS_1 like family ABC2_membrane_5 PF13346.6 CBY43348.1 - 2.3 7.7 7.5 0.52 9.8 3.8 1.8 1 1 1 2 2 2 0 ABC-2 family transporter protein VWA PF00092.28 CBY43349.1 - 0.042 14.1 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Cytochrom_B561 PF03188.16 CBY43350.1 - 0.025 14.7 0.2 0.025 14.7 0.2 1.4 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 T-box PF00907.22 CBY43353.1 - 2.2e-43 148.7 0.2 2.2e-43 148.7 0.2 1.6 2 0 0 2 2 2 1 T-box I-set PF07679.16 CBY43354.1 - 1.6e-13 50.5 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_3 PF13927.6 CBY43354.1 - 4.7e-09 36.7 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Ig_2 PF13895.6 CBY43354.1 - 4e-07 30.3 0.0 9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain ig PF00047.25 CBY43354.1 - 6.9e-06 26.1 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY43354.1 - 6e-05 23.2 0.1 0.015 15.5 0.1 2.4 1 1 0 1 1 1 1 Immunoglobulin V-set domain C1-set PF07654.15 CBY43354.1 - 0.0013 19.1 1.2 0.012 16.0 0.2 2.2 2 0 0 2 2 2 1 Immunoglobulin C1-set domain Izumo-Ig PF16706.5 CBY43354.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Pkinase PF00069.25 CBY43355.1 - 1.1e-50 172.5 0.0 1.5e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain I-set PF07679.16 CBY43355.1 - 2.6e-44 149.2 0.3 1.2e-20 73.3 0.0 3.4 2 1 1 3 3 3 3 Immunoglobulin I-set domain Pkinase_Tyr PF07714.17 CBY43355.1 - 1.5e-24 86.7 0.0 2.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ig_3 PF13927.6 CBY43355.1 - 6e-24 84.5 0.4 5.2e-09 36.6 0.1 3.4 3 0 0 3 3 3 3 Immunoglobulin domain Ig_2 PF13895.6 CBY43355.1 - 4.6e-08 33.3 1.5 0.12 12.7 0.2 3.3 3 0 0 3 3 3 3 Immunoglobulin domain ig PF00047.25 CBY43355.1 - 4.1e-07 30.1 3.4 0.075 13.2 0.2 3.3 3 0 0 3 3 3 3 Immunoglobulin domain C2-set_2 PF08205.12 CBY43355.1 - 9.7e-05 22.4 0.4 2.5 8.2 0.1 3.5 2 2 0 3 3 3 2 CD80-like C2-set immunoglobulin domain Kinase-like PF14531.6 CBY43355.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like V-set PF07686.17 CBY43355.1 - 0.00022 21.4 2.3 0.21 11.8 0.1 3.6 3 1 0 3 3 3 1 Immunoglobulin V-set domain Big_3_5 PF16640.5 CBY43355.1 - 0.01 16.0 1.9 0.085 13.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) RAP-1 PF03085.15 CBY43355.1 - 0.013 15.3 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) PI3_PI4_kinase PF00454.27 CBY43356.1 - 2.4e-09 37.4 0.1 5.2e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBY43356.1 - 1.5e-07 31.1 0.0 3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 FATC domain Kelch_5 PF13854.6 CBY43358.1 - 0.29 11.2 3.2 0.36 10.9 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 CBY43358.1 - 0.42 11.0 3.6 5 7.6 0.0 3.4 2 1 1 3 3 3 0 Kelch motif Kelch_2 PF07646.15 CBY43358.1 - 0.56 10.3 2.7 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Kelch motif SH2 PF00017.24 CBY43359.1 - 6.9e-11 42.1 0.1 1.3e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 SH2 domain RhoGAP PF00620.27 CBY43360.1 - 3.1e-17 62.8 0.0 4.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.22 CBY43360.1 - 5.2e-11 42.2 12.2 7.3e-11 41.8 12.2 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 CBY43360.1 - 0.1 12.6 6.1 0.19 11.8 6.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 CBY43360.1 - 0.14 12.1 9.5 0.25 11.3 9.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_2 PF13240.6 CBY43360.1 - 0.16 11.7 3.3 1.8 8.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CBY43360.1 - 0.26 11.2 3.7 0.56 10.2 3.7 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-RING_9 PF13901.6 CBY43360.1 - 3.1 7.7 13.2 7.6 6.4 10.8 2.2 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon Ion_trans PF00520.31 CBY43361.1 - 5.7e-85 284.5 35.1 5.5e-64 215.7 23.9 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 CBY43361.1 - 2.1e-08 33.3 26.0 1.2e-06 27.4 11.2 3.2 2 1 1 3 3 3 2 Polycystin cation channel GPHH PF16905.5 CBY43361.1 - 0.053 13.3 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated DUF4282 PF14110.6 CBY43361.1 - 0.32 11.8 0.1 0.32 11.8 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4282) HTH_9 PF08221.11 CBY43362.1 - 6.6e-06 26.1 0.3 0.019 15.0 0.0 2.8 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 CBY43362.1 - 0.00037 20.3 0.1 0.00072 19.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TPK_B1_binding PF04265.14 CBY43362.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain NEXCaM_BD PF16644.5 CBY43362.1 - 0.14 12.4 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin NAP PF00956.18 CBY43363.1 - 0.043 13.0 2.7 0.055 12.6 2.7 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) bZIP_1 PF00170.21 CBY43365.1 - 0.0068 16.5 7.6 0.0068 16.5 7.6 2.3 3 0 0 3 3 3 1 bZIP transcription factor MLD PF11647.8 CBY43365.1 - 0.026 14.8 1.7 0.038 14.3 0.8 1.7 2 0 0 2 2 2 0 Membrane Localization Domain DivIC PF04977.15 CBY43365.1 - 0.12 12.2 8.6 0.046 13.5 5.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Med21 PF11221.8 CBY43365.1 - 0.17 12.2 11.4 0.47 10.7 0.2 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex FlaC_arch PF05377.11 CBY43365.1 - 1.8 9.0 13.8 0.1 13.0 7.6 2.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YabA PF06156.13 CBY43365.1 - 2.5 8.8 10.7 2 9.1 8.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBY43365.1 - 7.3 7.1 18.1 0.085 13.3 9.0 2.3 3 0 0 3 3 3 0 Cell division protein ZapB Thioredoxin PF00085.20 CBY43366.1 - 1e-26 92.9 0.3 1.1e-26 92.7 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBY43366.1 - 9.1e-05 22.6 0.2 0.00012 22.2 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CBY43366.1 - 0.00084 19.6 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBY43366.1 - 0.0033 16.8 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY43366.1 - 0.0054 17.2 0.2 0.038 14.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY43366.1 - 0.0069 16.3 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBY43366.1 - 0.027 14.2 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 CBY43366.1 - 0.036 14.3 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin vATP-synt_E PF01991.18 CBY43367.1 - 0.0037 16.7 0.2 0.004 16.6 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phage_Mu_Gam PF07352.12 CBY43367.1 - 0.0039 17.1 0.5 0.0046 16.9 0.5 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Uds1 PF15456.6 CBY43367.1 - 0.015 15.5 0.7 0.022 14.9 0.7 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF2039 PF10217.9 CBY43367.1 - 0.015 15.6 0.4 0.018 15.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Peptidase_M19 PF01244.21 CBY43367.1 - 0.037 13.2 0.1 0.042 13.0 0.1 1.0 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Cut12 PF11500.8 CBY43367.1 - 0.059 13.3 2.8 0.13 12.3 2.8 1.5 1 1 0 1 1 1 0 Spindle pole body formation-associated protein TM1586_NiRdase PF14512.6 CBY43367.1 - 0.063 12.8 0.2 0.076 12.6 0.2 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase Prefoldin_2 PF01920.20 CBY43370.1 - 8e-15 54.7 4.7 9.6e-15 54.4 4.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit COG2 PF06148.11 CBY43370.1 - 0.034 14.2 0.5 0.05 13.7 0.5 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec2p PF06428.11 CBY43370.1 - 0.22 11.5 7.3 0.037 14.0 2.6 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p KELK PF15796.5 CBY43370.1 - 0.51 10.8 5.7 0.12 12.8 2.1 1.8 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4897 PF16238.5 CBY43376.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) HEAT PF02985.22 CBY43376.1 - 0.059 13.7 0.8 0.25 11.7 0.2 2.3 2 0 0 2 2 2 0 HEAT repeat RAC_head PF16717.5 CBY43376.1 - 0.21 12.6 4.4 0.31 12.0 1.8 2.2 1 1 1 2 2 2 0 Ribosome-associated complex head domain Complex1_49kDa PF00346.19 CBY43377.1 - 5e-119 396.4 0.0 6.1e-119 396.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CBY43377.1 - 0.029 13.3 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase SBDS_C PF09377.10 CBY43381.1 - 0.03 14.3 0.2 0.054 13.5 0.2 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain Dehydratase_LU PF02286.15 CBY43381.1 - 0.34 9.5 1.3 6 5.3 0.1 2.0 1 1 1 2 2 2 0 Dehydratase large subunit Med19 PF10278.9 CBY43382.1 - 2.6 7.9 10.8 2.9 7.8 10.8 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2443 PF10398.9 CBY43383.1 - 0.077 13.0 0.7 18 5.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) PLAC9 PF15205.6 CBY43383.1 - 0.1 13.0 1.9 0.25 11.8 1.9 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 ChW PF07538.11 CBY43387.1 - 0.11 12.5 0.2 1.3e+02 2.6 0.0 5.3 7 0 0 7 7 7 0 Clostridial hydrophobic W Kazal_1 PF00050.21 CBY43388.1 - 1.1e-44 150.2 59.8 1.5e-09 37.7 5.5 7.5 6 1 1 7 7 7 7 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 CBY43388.1 - 1.8e-43 146.4 57.3 8.6e-10 38.6 2.8 7.8 6 1 1 7 7 7 7 Kazal-type serine protease inhibitor domain Pkinase PF00069.25 CBY43392.1 - 2.9e-55 187.5 0.0 3.3e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43392.1 - 4.8e-26 91.6 0.0 6.5e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY43392.1 - 0.00057 18.9 0.1 0.00091 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBY43392.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CBY43392.1 - 0.045 12.5 0.0 0.091 11.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CBY43392.1 - 0.12 12.0 0.4 0.33 10.5 0.4 1.7 1 1 0 1 1 1 0 RIO1 family Ala_racemase_N PF01168.20 CBY43394.1 - 6.9e-15 55.3 0.0 7.8e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HTH_31 PF13560.6 CBY43394.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 CBY43394.1 - 0.067 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2683 PF10884.8 CBY43394.1 - 0.094 13.0 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) HTH_3 PF01381.22 CBY43394.1 - 0.095 12.8 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix CD36 PF01130.21 CBY43395.1 - 2.3e-42 145.1 0.0 2.8e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 CD36 family tRNA_SAD PF07973.14 CBY43396.1 - 2.3e-10 40.4 0.2 4.2e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CBY43396.1 - 6.2e-09 36.4 7.8 1.4e-08 35.3 6.5 2.1 1 1 0 1 1 1 1 DHHA1 domain Tropomyosin_1 PF12718.7 CBY43396.1 - 0.0028 17.8 5.0 0.0045 17.2 5.0 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF4775 PF16001.5 CBY43396.1 - 0.051 13.0 3.6 0.064 12.7 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) PGAP1 PF07819.13 CBY43396.1 - 0.061 13.0 0.3 0.092 12.4 0.3 1.2 1 0 0 1 1 1 0 PGAP1-like protein CAP PF00188.26 CBY43398.1 - 0.00013 22.8 0.0 0.0019 19.0 0.0 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3107 PF11305.8 CBY43398.1 - 0.00099 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) Med8 PF10232.9 CBY43400.1 - 2e-27 96.3 0.8 1.4e-25 90.3 0.8 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 ThrE PF06738.12 CBY43400.1 - 0.17 11.2 0.1 0.53 9.6 0.1 1.7 2 0 0 2 2 2 0 Putative threonine/serine exporter Presenilin PF01080.17 CBY43401.1 - 2.5 6.8 5.7 2.5 6.8 5.7 1.0 1 0 0 1 1 1 0 Presenilin PRP38_assoc PF12871.7 CBY43401.1 - 4.3 8.0 47.0 0.07 13.7 38.8 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 CBY43401.1 - 6 5.6 12.4 5.8 5.6 12.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_5 PF05631.14 CBY43402.1 - 1.9e-39 135.6 3.1 2.1e-39 135.5 3.1 1.0 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY43402.1 - 7e-09 35.1 8.2 2.4e-08 33.3 9.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBY43402.1 - 0.002 17.1 1.5 0.0023 16.9 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter zf-C4 PF00105.18 CBY43404.1 - 0.00034 21.0 1.2 0.00054 20.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C4 type (two domains) Sulfotransfer_1 PF00685.27 CBY43405.1 - 0.13 11.7 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Sulfotransferase domain Lectin_C PF00059.21 CBY43406.1 - 5.6e-15 56.0 0.2 7.3e-09 36.3 0.0 2.9 3 0 0 3 3 3 2 Lectin C-type domain OmpH PF03938.14 CBY43407.1 - 1.4 9.3 5.7 2.5 8.4 2.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CUB PF00431.20 CBY43409.1 - 5.8e-57 190.8 2.3 5.9e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 CUB domain EGF_CA PF07645.15 CBY43410.1 - 2.7e-62 206.7 127.3 1.9e-10 40.8 12.4 8.2 8 0 0 8 8 8 8 Calcium-binding EGF domain EGF_3 PF12947.7 CBY43410.1 - 7e-57 189.3 128.4 4e-09 36.5 10.1 8.3 8 0 0 8 8 8 8 EGF domain cEGF PF12662.7 CBY43410.1 - 4e-36 122.6 79.4 1.7e-07 31.1 4.2 9.5 10 0 0 10 10 10 8 Complement Clr-like EGF-like EGF PF00008.27 CBY43410.1 - 1.4e-24 86.1 111.1 0.00045 20.4 8.1 8.8 8 0 0 8 8 8 8 EGF-like domain EGF_MSP1_1 PF12946.7 CBY43410.1 - 3.4e-19 68.6 94.3 0.0022 18.0 7.1 8.2 8 0 0 8 8 8 7 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY43410.1 - 1.9e-18 66.5 101.5 0.00089 19.5 6.4 8.5 4 2 4 8 8 8 8 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.11 CBY43410.1 - 1.2e-11 44.7 99.5 0.0022 18.2 4.7 8.2 7 1 1 8 8 8 8 Pvs28 EGF domain hEGF PF12661.7 CBY43410.1 - 5.6e-09 36.3 108.1 0.0034 18.0 3.0 11.8 11 1 0 11 11 11 7 Human growth factor-like EGF EGF_2 PF07974.13 CBY43410.1 - 0.0015 18.9 106.3 0.0094 16.3 5.5 8.9 6 2 2 8 8 8 6 EGF-like domain Cnn_1N PF07989.11 CBY43411.1 - 0.007 16.5 1.9 0.0078 16.3 1.9 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SRP_TPR_like PF17004.5 CBY43411.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Putative TPR-like repeat NYD-SP28_assoc PF14775.6 CBY43411.1 - 0.025 14.7 0.9 0.038 14.1 0.1 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Myc-LZ PF02344.15 CBY43411.1 - 0.14 12.2 1.7 0.22 11.6 1.7 1.3 1 0 0 1 1 1 0 Myc leucine zipper domain Mt_ATP-synt_B PF05405.14 CBY43413.1 - 1.9e-10 40.6 7.8 2.3e-10 40.3 7.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4114 PF13448.6 CBY43413.1 - 1.3 9.9 4.4 8.5 7.3 4.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4114) Coatomer_E PF04733.14 CBY43416.1 - 8.5e-24 84.5 0.1 8.9e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit DUF3114 PF11311.8 CBY43416.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3114) Ferritin PF00210.24 CBY43417.1 - 0.045 13.7 1.3 0.24 11.4 0.0 2.6 1 1 2 3 3 3 0 Ferritin-like domain GlutR_dimer PF00745.20 CBY43417.1 - 0.15 12.5 1.5 2.1 8.9 0.1 2.7 2 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4378 PF14309.6 CBY43417.1 - 0.41 11.0 5.7 0.11 12.9 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) DUF4375 PF14300.6 CBY43417.1 - 4.5 7.5 6.6 2.8 8.2 0.1 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4375) EGF_CA PF07645.15 CBY43418.1 - 2.2e-05 24.5 9.4 3.8e-05 23.8 9.4 1.4 1 0 0 1 1 1 1 Calcium-binding EGF domain CMV_1a PF12467.8 CBY43418.1 - 0.053 13.9 0.4 0.096 13.0 0.4 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Fzo_mitofusin PF04799.13 CBY43418.1 - 0.22 11.0 1.0 0.45 10.1 1.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Pkinase PF00069.25 CBY43419.1 - 0.038 13.3 0.1 0.096 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Pox_Ag35 PF03286.14 CBY43419.1 - 0.046 13.5 8.2 0.061 13.1 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Fmp27 PF10344.9 CBY43419.1 - 0.52 8.3 1.7 0.54 8.3 1.7 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 LAT PF15234.6 CBY43419.1 - 3.2 7.4 7.6 1.6 8.4 4.9 1.6 1 1 1 2 2 2 0 Linker for activation of T-cells Transket_pyr PF02779.24 CBY43420.1 - 1.6e-44 151.7 0.1 2.1e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBY43420.1 - 1.9e-24 85.9 0.0 4.6e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBY43420.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Acyl-CoA_dh_N PF02771.16 CBY43420.1 - 0.13 13.0 0.5 0.35 11.5 0.5 1.9 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Glutaredoxin PF00462.24 CBY43421.1 - 1.8e-15 56.9 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Exo_endo_phos PF03372.23 CBY43422.1 - 0.0041 16.7 0.0 0.0043 16.6 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cauli_VI PF01693.16 CBY43423.1 - 3.2e-21 75.4 5.2 1.2e-12 47.9 0.6 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin DUF5403 PF17395.2 CBY43429.1 - 0.081 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5403) ABC_tran PF00005.27 CBY43430.1 - 4.8e-34 117.8 0.3 7.2e-34 117.2 0.3 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBY43430.1 - 1.6e-07 31.0 0.4 4.6e-06 26.2 0.1 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CBY43430.1 - 2.5e-06 27.4 0.1 3.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 CBY43430.1 - 0.00053 20.4 0.1 0.0011 19.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 CBY43430.1 - 0.0026 18.0 0.5 0.042 14.1 0.5 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBY43430.1 - 0.0027 17.6 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase DUF4447 PF14590.6 CBY43430.1 - 0.0044 16.8 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4447) DUF815 PF05673.13 CBY43430.1 - 0.0072 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 CBY43430.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBY43430.1 - 0.01 16.1 0.1 0.035 14.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBY43430.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBY43430.1 - 0.015 15.7 0.1 0.25 11.8 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBY43430.1 - 0.029 14.3 0.1 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 CBY43430.1 - 0.034 14.3 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 CBY43430.1 - 0.039 13.7 0.2 0.19 11.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBY43430.1 - 0.041 13.9 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBY43430.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 CBY43430.1 - 0.093 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CBY43430.1 - 0.1 13.0 0.0 0.81 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 CBY43430.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ion_trans_2 PF07885.16 CBY43431.1 - 2.4e-07 30.6 2.1 3.2e-07 30.2 2.1 1.2 1 0 0 1 1 1 1 Ion channel Form_Nir_trans PF01226.17 CBY43431.1 - 0.018 14.4 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter Ion_trans PF00520.31 CBY43431.1 - 0.026 13.7 2.7 0.035 13.3 2.7 1.2 1 0 0 1 1 1 0 Ion transport protein TrkH PF02386.16 CBY43431.1 - 0.056 11.9 1.1 0.094 11.1 1.1 1.4 1 1 0 1 1 1 0 Cation transport protein zf-C3HC4_3 PF13920.6 CBY43432.1 - 8e-07 28.8 5.9 1.4e-06 28.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBY43432.1 - 2.1e-06 27.5 9.0 3.8e-06 26.7 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY43432.1 - 7.6e-06 26.2 8.5 1.8e-05 25.0 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBY43432.1 - 1.4e-05 24.9 7.5 3.1e-05 23.7 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBY43432.1 - 5.1e-05 23.2 2.7 9.4e-05 22.4 1.3 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CBY43432.1 - 0.00033 20.4 5.4 0.00075 19.2 5.4 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY43432.1 - 0.0042 16.9 7.7 0.011 15.5 7.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CBY43432.1 - 0.0052 16.6 3.8 0.0095 15.8 3.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CBY43432.1 - 0.008 16.0 9.3 0.018 14.8 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FIN1 PF17300.2 CBY43432.1 - 0.012 15.1 2.1 0.018 14.6 2.1 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Rtf2 PF04641.12 CBY43432.1 - 0.038 13.3 3.2 0.046 13.1 2.8 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 CBY43432.1 - 0.039 13.7 4.4 0.12 12.2 4.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger Mito_fiss_reg PF05308.11 CBY43432.1 - 0.061 13.4 4.4 0.089 12.9 3.4 1.7 1 1 0 2 2 2 0 Mitochondrial fission regulator zf-UDP PF14569.6 CBY43432.1 - 0.22 11.6 3.4 0.51 10.5 3.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2H2_4 PF13894.6 CBY43432.1 - 2.1 9.4 7.1 12 7.0 0.2 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 CBY43432.1 - 3 8.1 10.4 4.2 7.6 6.7 2.6 2 1 1 3 3 3 0 FYVE zinc finger HSP20 PF00011.21 CBY43433.1 - 2.3e-06 27.7 4.5 2.5e-05 24.3 0.6 3.1 3 0 0 3 3 3 2 Hsp20/alpha crystallin family Chorion_2 PF03964.15 CBY43433.1 - 1.2 10.0 8.4 0.67 10.8 2.9 2.3 1 1 1 2 2 2 0 Chorion family 2 Cyclin_N PF00134.23 CBY43434.1 - 6.3e-33 113.2 3.8 6.3e-33 113.2 3.8 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBY43434.1 - 1.5e-21 76.7 1.1 1.5e-21 76.7 1.1 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain FGGY_C PF02782.16 CBY43436.1 - 1.9e-06 27.8 0.5 0.00019 21.2 0.1 2.2 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain MRP-S24 PF14955.6 CBY43436.1 - 0.14 12.1 0.1 0.19 11.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 eIF-3c_N PF05470.12 CBY43438.1 - 9e-37 126.7 24.0 9.3e-37 126.6 23.3 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF167 PF02594.16 CBY43439.1 - 2.4e-20 72.4 0.6 3.6e-20 71.8 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 ig PF00047.25 CBY43440.1 - 2.9e-06 27.4 1.1 6.3e-06 26.3 0.6 1.9 2 0 0 2 2 2 1 Immunoglobulin domain Ig_3 PF13927.6 CBY43440.1 - 3.2e-06 27.7 0.5 1.1e-05 25.9 0.5 2.0 1 0 0 1 1 1 1 Immunoglobulin domain V-set PF07686.17 CBY43440.1 - 0.00016 21.8 0.4 0.0007 19.7 0.4 2.1 1 1 0 1 1 1 1 Immunoglobulin V-set domain I-set PF07679.16 CBY43440.1 - 0.00036 20.5 0.2 0.0006 19.8 0.2 1.4 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY43440.1 - 0.00085 19.6 0.3 0.0022 18.3 0.3 1.8 1 0 0 1 1 1 1 Immunoglobulin domain C2-set PF05790.15 CBY43440.1 - 0.0073 16.5 0.2 0.028 14.6 0.1 2.1 1 1 1 2 2 2 1 Immunoglobulin C2-set domain Receptor_2B4 PF11465.8 CBY43440.1 - 0.17 12.1 0.3 0.45 10.7 0.2 1.8 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 EphA2_TM PF14575.6 CBY43440.1 - 0.18 12.7 1.0 0.6 11.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 CBY43440.1 - 0.28 12.2 1.5 1.6 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SKG6 PF08693.10 CBY43440.1 - 0.48 9.9 3.2 1.7 8.2 3.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF866 PF05907.13 CBY43441.1 - 0.012 15.6 0.3 0.024 14.6 0.2 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF3920 PF13058.6 CBY43441.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) zf-HYPF PF07503.12 CBY43441.1 - 3.9 7.3 11.9 2.3 8.1 1.8 2.9 3 0 0 3 3 3 0 HypF finger Peroxin-13_N PF04088.13 CBY43442.1 - 0.1 12.8 3.4 0.12 12.6 3.4 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DegV PF02645.16 CBY43442.1 - 0.17 11.2 4.6 0.21 10.9 4.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 SPC22 PF04573.12 CBY43442.1 - 0.26 10.7 3.0 0.34 10.4 3.0 1.2 1 0 0 1 1 1 0 Signal peptidase subunit TRAP-gamma PF07074.12 CBY43442.1 - 0.28 10.7 4.3 0.31 10.6 4.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4775 PF16001.5 CBY43442.1 - 2.2 7.6 11.7 2.4 7.5 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) C2 PF00168.30 CBY43444.1 - 1.3e-21 76.8 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 CBY43444.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.3 1 1 0 1 1 1 0 CEP76 C2 domain BCS1_N PF08740.11 CBY43445.1 - 5.2e-09 36.3 0.1 7.2e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 BCS1 N terminal DUF4082 PF13313.6 CBY43445.1 - 0.067 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) AAA PF00004.29 CBY43446.1 - 2.7e-18 66.7 0.0 4.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBY43446.1 - 0.0003 21.2 0.6 0.014 15.8 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CBY43446.1 - 0.006 15.8 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CBY43446.1 - 0.0084 16.7 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain BCS1_N PF08740.11 CBY43446.1 - 0.0085 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA_28 PF13521.6 CBY43446.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBY43446.1 - 0.026 14.9 0.0 0.068 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY43446.1 - 0.029 14.1 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBY43446.1 - 0.036 14.6 0.0 0.11 13.1 0.0 1.8 1 1 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 CBY43446.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBY43446.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 CBY43446.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 CBY43446.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBY43446.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBY43446.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CBY43446.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBY43446.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 CBY43446.1 - 0.12 12.2 0.3 2.1 8.2 0.0 2.6 1 1 2 3 3 3 0 RsgA GTPase ANKH PF07260.11 CBY43447.1 - 0.058 12.6 3.2 0.67 9.1 0.1 2.1 1 1 1 2 2 2 0 Progressive ankylosis protein (ANKH) TrbC PF04956.13 CBY43447.1 - 0.44 10.8 7.0 0.93 9.8 3.8 2.6 2 1 1 3 3 3 0 TrbC/VIRB2 family CrgA PF06781.12 CBY43447.1 - 0.97 9.5 4.1 3.4 7.8 0.5 2.5 2 1 1 3 3 3 0 Cell division protein CrgA Peptidase_M14 PF00246.24 CBY43448.1 - 6.6e-24 85.2 0.0 7.6e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Pkinase PF00069.25 CBY43449.1 - 7.9e-27 94.3 0.0 9.1e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43449.1 - 2.1e-09 37.1 0.0 2.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBY43449.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RAMP4 PF06624.12 CBY43449.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 zf-RING_2 PF13639.6 CBY43450.1 - 1.6e-05 25.1 3.8 1.6e-05 25.1 3.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBY43450.1 - 0.0003 20.8 2.9 0.00079 19.4 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBY43450.1 - 0.0072 16.3 6.8 0.0072 16.3 6.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBY43450.1 - 0.019 14.8 5.0 0.019 14.8 5.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBY43450.1 - 0.39 10.5 4.8 0.89 9.4 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBY43450.1 - 0.55 10.1 9.7 0.065 13.1 4.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBY43450.1 - 2.9 8.1 6.8 0.65 10.2 2.6 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 CBY43451.1 - 2.6e-22 79.8 0.1 3.8e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBY43451.1 - 6.8e-05 22.8 0.8 0.027 14.3 1.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBY43451.1 - 0.00073 20.1 0.1 0.00089 19.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CBY43451.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBY43451.1 - 0.018 15.3 0.2 0.032 14.5 0.2 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBY43451.1 - 0.02 14.8 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CBY43451.1 - 0.034 14.7 0.1 0.043 14.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 CBY43451.1 - 0.035 12.7 0.6 0.056 12.1 0.6 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBY43451.1 - 0.036 14.3 0.1 0.04 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CBY43451.1 - 0.043 13.4 1.1 0.14 11.7 0.5 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBY43451.1 - 0.052 13.5 0.9 0.064 13.2 0.9 1.7 1 1 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CBY43451.1 - 0.089 12.5 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CBY43451.1 - 0.15 12.3 0.2 0.31 11.3 0.1 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CBY43451.1 - 0.17 11.9 0.3 0.59 10.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CBY43451.1 - 0.18 11.8 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CBY43451.1 - 0.24 11.5 1.6 0.76 9.9 1.6 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Glyco_transf_64 PF09258.10 CBY43452.1 - 9.9e-16 57.8 0.0 1.1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Iso_dh PF00180.20 CBY43453.1 - 3.4e-43 148.1 0.1 4e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IDH PF03971.14 CBY43453.1 - 0.015 13.8 0.3 0.02 13.3 0.3 1.2 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase COesterase PF00135.28 CBY43454.1 - 2.2e-05 23.5 0.7 4e-05 22.7 0.7 1.4 1 1 0 1 1 1 1 Carboxylesterase family Kelch_2 PF07646.15 CBY43456.1 - 0.0085 16.0 0.3 0.31 11.1 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Pkinase PF00069.25 CBY43457.1 - 2.9e-23 82.6 0.0 3.3e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43457.1 - 2.4e-15 56.5 0.0 2.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBY43457.1 - 0.00012 22.0 0.0 0.00041 20.4 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBY43457.1 - 0.0025 16.8 0.1 0.0034 16.4 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CBY43457.1 - 0.0091 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBY43457.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CBY43457.1 - 0.11 12.0 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 CBY43459.1 - 7.8e-60 202.5 0.0 9.1e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43459.1 - 5e-41 140.7 0.0 6e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBY43459.1 - 2.3e-05 23.5 0.3 7.7e-05 21.8 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBY43459.1 - 0.00026 19.9 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY43459.1 - 0.00062 19.2 0.1 0.0018 17.7 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CBY43459.1 - 0.0022 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBY43459.1 - 0.012 15.2 0.2 0.2 11.2 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RuvC_1 PF18516.1 CBY43459.1 - 0.077 12.2 0.3 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 RuvC nuclease domain APH PF01636.23 CBY43459.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CBY43463.1 - 1.6e-28 99.7 0.5 1.7e-23 83.2 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBY43463.1 - 2.9e-12 46.5 1.8 4.7e-11 42.6 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain SieB PF14163.6 CBY43463.1 - 0.00098 18.6 0.1 0.0029 17.1 0.1 1.7 1 0 0 1 1 1 1 Super-infection exclusion protein B Ig_3 PF13927.6 CBY43463.1 - 0.016 15.8 0.0 0.035 14.7 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain Ig_2 PF13895.6 CBY43463.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain V-set PF07686.17 CBY43463.1 - 0.12 12.6 0.7 0.41 10.8 0.0 2.1 2 1 0 2 2 2 0 Immunoglobulin V-set domain Pro_isomerase PF00160.21 CBY43467.1 - 1.4e-48 165.2 1.2 1.2e-47 162.1 0.1 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CBY43467.1 - 8.2e-06 25.4 2.8 9.5e-06 25.2 1.9 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger MOSC_N PF03476.16 CBY43468.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain Tubulin-binding PF00418.19 CBY43472.1 - 1.7e-91 299.8 51.0 2.2e-15 56.3 1.4 8.5 9 0 0 9 9 9 8 Tau and MAP protein, tubulin-binding repeat UXS1_N PF11803.8 CBY43472.1 - 0.0075 16.6 2.5 46 4.5 0.0 5.2 2 2 4 6 6 6 1 UDP-glucuronate decarboxylase N-terminal Ocnus PF05005.15 CBY43472.1 - 0.25 11.5 9.4 0.77 9.9 0.3 3.9 2 2 2 4 4 4 0 Janus/Ocnus family (Ocnus) AvrE_T3Es PF11725.8 CBY43473.1 - 0.28 8.3 2.0 0.31 8.2 2.0 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) DUF2457 PF10446.9 CBY43473.1 - 1.7 7.7 7.5 2.1 7.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNase_T PF00929.24 CBY43474.1 - 2.1e-19 70.7 0.0 3.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease PLU-1 PF08429.11 CBY43474.1 - 0.033 13.4 0.1 0.06 12.5 0.1 1.3 1 0 0 1 1 1 0 PLU-1-like protein IncE PF17627.2 CBY43475.1 - 0.0036 17.3 8.0 0.46 10.5 0.0 2.2 1 1 1 2 2 2 2 Inclusion membrane protein E Peptidase_S74 PF13884.6 CBY43476.1 - 0.17 12.2 0.0 21 5.5 0.0 2.4 2 0 0 2 2 2 0 Chaperone of endosialidase Adaptin_N PF01602.20 CBY43479.1 - 1.2e-117 393.7 8.1 1.4e-117 393.4 8.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 CBY43479.1 - 4.8e-19 68.5 1.8 5.4e-08 33.1 0.0 6.4 3 2 3 6 6 6 3 HEAT repeats Cnd1 PF12717.7 CBY43479.1 - 1.9e-14 54.0 14.8 1.6e-05 25.0 0.7 5.2 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBY43479.1 - 0.00056 19.9 9.3 17 6.0 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.6 CBY43479.1 - 0.00097 19.6 2.7 0.42 11.2 0.4 5.0 5 1 1 6 6 6 1 HEAT-like repeat DNA_alkylation PF08713.11 CBY43479.1 - 0.0016 18.2 0.4 0.0075 16.0 0.1 2.3 4 0 0 4 4 4 1 DNA alkylation repair enzyme HEAT_PBS PF03130.16 CBY43479.1 - 0.0016 18.9 0.1 2 9.3 0.1 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.23 CBY43479.1 - 0.0037 17.2 0.3 6.1 7.0 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 CBY43479.1 - 0.06 13.3 1.0 0.34 10.8 0.2 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Rpr2 PF04032.16 CBY43480.1 - 0.00034 20.8 1.1 0.00069 19.9 1.1 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1660 PF07874.11 CBY43480.1 - 0.44 11.1 6.3 0.48 11.0 1.7 2.4 1 1 1 2 2 2 0 Prophage protein (DUF1660) MFS_5 PF05631.14 CBY43481.1 - 1.5e-43 149.1 9.1 2e-43 148.7 9.1 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CBY43481.1 - 9.3e-07 28.1 25.0 9.3e-07 28.1 25.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_1 PF05106.12 CBY43481.1 - 1.7 9.2 6.0 0.67 10.4 0.3 3.0 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Ras PF00071.22 CBY43483.1 - 1.5e-32 112.4 0.0 2.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBY43483.1 - 1.8e-23 83.0 0.2 3.9e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBY43483.1 - 1.4e-11 44.2 0.0 3.6e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBY43483.1 - 0.00028 20.3 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBY43483.1 - 0.00034 20.7 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBY43483.1 - 0.012 15.1 0.0 0.053 13.1 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CBY43483.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBY43483.1 - 0.2 11.7 0.5 0.63 10.1 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 CBY43483.1 - 0.25 11.1 1.2 2.5 7.8 0.2 2.4 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Homeodomain PF00046.29 CBY43484.1 - 0.0096 15.7 8.4 0.0096 15.7 8.4 1.8 2 0 0 2 2 2 1 Homeodomain DEP PF00610.21 CBY43485.1 - 3.5e-09 36.6 0.0 6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EMP70 PF02990.16 CBY43486.1 - 4.8e-41 141.0 0.7 6e-41 140.7 0.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Phage_DNA_bind PF02303.17 CBY43486.1 - 0.045 14.0 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-destabilising protein Cys_rich_FGFR PF00839.17 CBY43487.1 - 0.00018 21.6 0.8 0.00025 21.2 0.2 1.5 2 0 0 2 2 2 1 Cysteine rich repeat Patatin PF01734.22 CBY43488.1 - 8.4 6.5 9.1 14 5.7 8.4 1.6 1 1 0 1 1 1 0 Patatin-like phospholipase bZIP_1 PF00170.21 CBY43491.1 - 6.5e-09 35.8 13.0 1.3e-08 34.8 13.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CBY43491.1 - 0.00032 20.7 13.5 0.00066 19.7 13.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.11 CBY43491.1 - 0.096 12.0 1.7 0.16 11.4 1.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TPR_1 PF00515.28 CBY43493.1 - 9.3e-14 50.6 1.3 0.00045 19.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBY43493.1 - 3.4e-13 48.6 3.4 0.00051 20.0 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBY43493.1 - 4.7e-10 39.8 1.4 5.8e-06 26.7 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBY43493.1 - 6.8e-08 33.0 1.5 0.00013 22.5 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBY43493.1 - 1.2e-07 31.9 0.7 0.022 15.6 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBY43493.1 - 7.8e-07 28.8 3.1 0.46 10.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBY43493.1 - 1.3e-06 28.0 1.0 0.0021 17.7 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CBY43493.1 - 0.00011 22.4 2.0 1.5 9.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBY43493.1 - 0.00012 22.2 0.6 0.00023 21.3 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBY43493.1 - 0.00031 20.9 0.4 1.7 9.2 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBY43493.1 - 0.00061 20.3 4.3 1.2 9.9 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBY43493.1 - 0.0047 17.0 1.9 0.013 15.7 1.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBY43493.1 - 0.0076 16.1 1.5 17 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBY43493.1 - 0.012 16.1 0.1 0.55 10.7 0.2 2.5 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation BTAD PF03704.17 CBY43493.1 - 0.017 15.5 1.0 0.47 10.9 1.6 2.6 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Arnt_C PF18583.1 CBY43493.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain WD40 PF00400.32 CBY43495.1 - 1e-23 83.1 2.9 4.9e-07 30.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY43495.1 - 1.1e-08 35.3 0.0 0.00076 19.7 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY43495.1 - 0.0008 18.2 0.6 0.94 8.0 0.0 3.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CBY43495.1 - 0.0054 15.7 0.1 0.069 12.1 0.0 2.6 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CBY43495.1 - 0.08 13.0 0.0 0.46 10.5 0.0 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CBY43495.1 - 0.081 12.2 0.0 5.8 6.1 0.0 2.3 1 1 0 2 2 2 0 WD40-like domain PB1 PF00564.24 CBY43499.1 - 0.0001 22.1 0.1 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 PB1 domain RNaseH_pPIWI_RE PF13032.6 CBY43499.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE GPP34 PF05719.11 CBY43501.1 - 0.0003 20.9 0.1 0.00066 19.8 0.1 1.6 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Troponin PF00992.20 CBY43502.1 - 3.8e-20 72.6 37.8 9.1e-15 55.1 32.9 2.0 1 1 1 2 2 2 2 Troponin DUF4366 PF14283.6 CBY43502.1 - 0.041 13.9 4.7 0.069 13.2 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VIT1 PF01988.19 CBY43502.1 - 0.14 12.0 5.3 0.23 11.3 5.3 1.3 1 0 0 1 1 1 0 VIT family DUF4047 PF13256.6 CBY43502.1 - 3.4 7.9 13.1 0.66 10.2 9.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Asp-B-Hydro_N PF05279.11 CBY43502.1 - 5.3 7.0 21.2 7.6 6.5 21.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.12 CBY43502.1 - 6.9 6.4 17.4 9.9 5.9 17.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CBM_14 PF01607.24 CBY43503.1 - 3.6e-11 43.1 5.2 3.6e-11 43.1 5.2 1.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain PAN_1 PF00024.26 CBY43504.1 - 1.7e-05 24.7 1.5 4.2e-05 23.4 1.5 1.7 1 0 0 1 1 1 1 PAN domain DUF1759 PF03564.15 CBY43504.1 - 0.035 14.1 1.0 0.064 13.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) YebO PF13974.6 CBY43504.1 - 0.56 10.3 6.9 1.6 8.8 6.9 1.8 1 0 0 1 1 1 0 YebO-like protein FUSC PF04632.12 CBY43504.1 - 4.2 5.8 7.1 5.3 5.5 7.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cullin PF00888.22 CBY43505.1 - 1.1e-17 64.0 0.1 1.2e-17 63.8 0.1 1.0 1 0 0 1 1 1 1 Cullin family IDO PF01231.18 CBY43506.1 - 2.8e-52 178.0 0.6 3.3e-52 177.7 0.6 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AbiTii PF18864.1 CBY43506.1 - 0.1 12.8 0.5 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 AbiTii DUF5316 PF17247.2 CBY43507.1 - 3.6 7.7 5.9 0.32 11.0 1.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Aldedh PF00171.22 CBY43508.1 - 2.6e-81 273.5 0.0 3.4e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CBY43508.1 - 0.054 13.4 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CDC45 PF02724.14 CBY43510.1 - 4.8 5.3 9.0 5 5.3 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 CBY43510.1 - 10 5.0 13.8 13 4.7 13.8 1.1 1 0 0 1 1 1 0 Paf1 MCD PF05292.11 CBY43511.1 - 3.7e-39 134.8 0.1 5.5e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 CBY43511.1 - 0.0062 16.6 0.0 0.026 14.6 0.0 2.1 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase N-terminal domain COX6B PF02297.17 CBY43512.1 - 1.5e-18 66.8 6.4 4.7e-18 65.2 6.4 1.7 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cullin PF00888.22 CBY43513.1 - 9.5e-138 460.5 8.4 1.3e-137 460.1 8.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBY43513.1 - 2.1e-23 82.1 1.1 4.4e-23 81.1 0.1 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_20 PF12840.7 CBY43513.1 - 0.15 12.2 0.1 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain BSD PF03909.17 CBY43514.1 - 2.4e-08 33.9 0.3 2.4e-08 33.9 0.3 2.5 2 0 0 2 2 2 1 BSD domain DUF1451 PF07295.11 CBY43514.1 - 0.047 13.7 6.1 0.24 11.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain OTU PF02338.19 CBY43515.1 - 0.021 15.3 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease CUB PF00431.20 CBY43519.1 - 4.4e-11 43.1 0.0 7.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 CUB domain FXa_inhibition PF14670.6 CBY43519.1 - 0.0013 19.0 11.9 0.0048 17.2 11.9 2.0 1 1 0 1 1 1 1 Coagulation Factor Xa inhibitory site SPX PF03105.19 CBY43519.1 - 0.069 13.1 5.6 0.098 12.6 5.6 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CBY43519.1 - 5.1 5.8 10.0 8.5 5.1 10.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain NDUFA12 PF05071.16 CBY43520.1 - 1.7e-06 28.8 12.8 1.8e-05 25.5 12.8 2.3 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Spt5_N PF11942.8 CBY43520.1 - 0.19 12.8 5.6 0.26 12.3 5.2 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.25 CBY43521.1 - 3.7e-51 174.0 0.0 4.6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43521.1 - 2.4e-38 131.9 0.0 2.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBY43521.1 - 0.00032 19.6 0.1 0.0071 15.2 0.0 2.0 1 1 1 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CBY43521.1 - 0.00066 19.1 0.0 0.0009 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY43521.1 - 0.03 14.2 0.1 0.069 13.1 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family NB-ARC PF00931.22 CBY43524.1 - 0.051 12.8 0.5 0.098 11.8 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain CDH1_2_SANT_HL1 PF18375.1 CBY43524.1 - 0.34 11.6 0.1 0.34 11.6 0.1 2.2 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 DUF3437 PF11919.8 CBY43524.1 - 0.39 10.6 2.1 17 5.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Peptidase_S10 PF00450.22 CBY43525.1 - 2.8e-110 369.6 1.0 3.1e-110 369.5 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2920 PF11144.8 CBY43525.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Ank_2 PF12796.7 CBY43527.1 - 9.5e-08 32.5 0.0 2.2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY43527.1 - 1.1e-07 32.3 0.0 3.3e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY43527.1 - 6.7e-06 26.1 0.0 0.015 15.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat NUC194 PF08163.12 CBY43527.1 - 7.6e-05 21.8 0.1 0.0001 21.4 0.1 1.2 1 0 0 1 1 1 1 NUC194 domain Ank PF00023.30 CBY43527.1 - 0.0017 18.7 0.1 0.45 11.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeat Post_transc_reg PF13797.6 CBY43527.1 - 0.07 13.0 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Post-transcriptional regulator PRP8_domainIV PF12134.8 CBY43529.1 - 0.04 13.6 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 PRP8 domain IV core Ion_trans PF00520.31 CBY43530.1 - 5.1e-13 48.8 16.8 6.7e-13 48.4 16.8 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_7 PF13499.6 CBY43532.1 - 3e-07 30.8 2.6 1.6e-06 28.4 2.7 2.1 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBY43532.1 - 1e-06 28.5 0.5 2.2e-06 27.4 0.4 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBY43532.1 - 2.7e-06 26.5 1.4 1.7e-05 24.1 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBY43532.1 - 8e-06 25.4 1.2 3.4e-05 23.4 0.1 2.5 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 CBY43532.1 - 0.0006 19.2 0.8 0.0016 17.8 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 CBY43532.1 - 0.021 14.7 0.2 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 CBY43532.1 - 0.057 13.4 0.5 0.16 11.9 0.5 1.8 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Ig_2 PF13895.6 CBY43533.1 - 3.9e-06 27.1 1.9 0.051 13.9 0.5 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_3 PF13927.6 CBY43533.1 - 5.1e-06 27.0 2.9 0.049 14.2 1.3 2.3 2 0 0 2 2 2 2 Immunoglobulin domain Ig_C17orf99 PF17736.1 CBY43533.1 - 0.029 14.4 0.6 0.099 12.7 0.1 2.0 2 0 0 2 2 2 0 C17orf99 Ig domain TIG PF01833.24 CBY43534.1 - 2.7e-13 49.8 7.7 6.2e-08 32.6 1.6 2.8 2 1 0 2 2 2 2 IPT/TIG domain Mucin2_WxxW PF13330.6 CBY43534.1 - 3.4e-11 43.8 0.4 9.6e-11 42.4 0.4 1.8 1 0 0 1 1 1 1 Mucin-2 protein WxxW repeating region GLEYA PF10528.9 CBY43534.1 - 8.9e-06 26.0 1.5 4.4e-05 23.8 0.1 2.8 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.12 CBY43534.1 - 0.00033 20.5 0.3 0.0008 19.2 0.1 1.8 2 0 0 2 2 2 1 PA14 domain Sec7_N PF12783.7 CBY43535.1 - 6.6e-16 58.6 6.1 7.6e-16 58.4 0.3 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CBY43535.1 - 3.3e-13 49.3 1.5 5e-11 42.3 0.1 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) RRM_1 PF00076.22 CBY43539.1 - 6e-19 67.6 0.0 1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.6 CBY43539.1 - 4.3e-11 43.1 0.6 2.8e-08 34.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBY43539.1 - 6.7e-10 39.0 0.3 6.4e-05 23.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CBY43539.1 - 7.8e-10 39.2 0.4 3.6e-09 37.1 0.4 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBY43539.1 - 1e-08 34.7 0.2 0.015 15.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBY43539.1 - 1.7e-08 34.5 0.3 6.9e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 CBY43540.1 - 0.00031 21.2 1.8 0.034 14.7 0.0 2.4 2 0 0 2 2 2 2 PH domain PDZ PF00595.24 CBY43542.1 - 2.7e-07 30.9 0.2 4.6e-07 30.1 0.2 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBY43542.1 - 0.00012 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain ssDBP_DBD PF18361.1 CBY43543.1 - 0.019 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Cep57_CLD PF14073.6 CBY43543.1 - 0.03 14.4 5.5 0.03 14.4 5.5 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 DUF4085 PF13315.6 CBY43543.1 - 0.049 13.3 7.4 1.6 8.3 2.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4085) CemA PF03040.14 CBY43543.1 - 0.12 12.3 2.5 0.16 11.9 2.5 1.2 1 0 0 1 1 1 0 CemA family Mis12 PF05859.12 CBY43543.1 - 0.22 11.6 3.5 3.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Mis12 protein TMCO5 PF14992.6 CBY43543.1 - 0.27 10.8 11.8 0.38 10.3 11.8 1.3 1 0 0 1 1 1 0 TMCO5 family Lzipper-MIP1 PF14389.6 CBY43543.1 - 0.3 11.4 10.1 2.7 8.3 2.5 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 MADF_DNA_bdg PF10545.9 CBY43543.1 - 0.54 10.6 8.1 0.067 13.5 1.9 2.1 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3899 PF13038.6 CBY43543.1 - 0.54 10.8 2.3 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Myb_DNA-bind_4 PF13837.6 CBY43543.1 - 0.56 10.6 11.8 0.094 13.1 4.5 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CREPT PF16566.5 CBY43543.1 - 0.91 9.7 12.0 1.7 8.8 11.5 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FAM184 PF15665.5 CBY43543.1 - 1 9.1 13.6 2 8.1 13.6 1.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF16 PF01519.16 CBY43543.1 - 6 7.4 9.9 0.86 10.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 IGFBP PF00219.18 CBY43545.1 - 0.04 14.6 1.9 0.04 14.6 1.9 1.5 2 0 0 2 2 2 0 Insulin-like growth factor binding protein p450 PF00067.22 CBY43547.1 - 4.4e-17 62.0 0.1 4.8e-17 61.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 THOC7 PF05615.13 CBY43548.1 - 0.00049 20.4 18.2 0.00049 20.4 18.2 3.5 1 1 1 3 3 3 1 Tho complex subunit 7 Csm1_N PF18504.1 CBY43548.1 - 0.025 14.9 6.2 0.025 14.9 6.2 4.9 2 2 2 4 4 3 0 Csm1 N-terminal domain Taxilin PF09728.9 CBY43548.1 - 0.048 12.9 47.8 0.071 12.3 47.8 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein SNCAIP_SNCA_bd PF16700.5 CBY43548.1 - 0.048 13.4 1.5 0.048 13.4 1.5 2.7 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF2935 PF11155.8 CBY43548.1 - 0.063 13.6 17.2 0.075 13.4 2.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) DivIC PF04977.15 CBY43548.1 - 0.082 12.7 52.3 0.12 12.2 4.7 5.8 1 1 5 6 6 6 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 CBY43548.1 - 0.11 12.7 51.6 6.5 7.0 8.5 3.8 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 CBY43548.1 - 0.27 10.1 47.7 0.91 8.3 21.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein 7tm_7 PF08395.12 CBY43548.1 - 0.31 10.2 1.6 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Uso1_p115_C PF04871.13 CBY43548.1 - 0.37 11.2 48.7 2.3 8.6 9.1 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CEP63 PF17045.5 CBY43548.1 - 0.4 10.6 48.1 8.9 6.1 37.1 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa EzrA PF06160.12 CBY43548.1 - 0.47 8.6 43.2 0.051 11.8 29.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 CBY43548.1 - 0.52 10.8 55.3 0.88 10.1 20.4 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF724 PF05266.14 CBY43548.1 - 0.67 9.8 41.7 0.44 10.4 9.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) PhoU PF01895.19 CBY43548.1 - 2 9.0 17.6 0.27 11.7 0.4 3.8 2 1 2 4 4 4 0 PhoU domain TPR_MLP1_2 PF07926.12 CBY43548.1 - 2.2 8.4 51.8 0.098 12.7 26.3 3.2 1 1 2 3 3 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CBY43548.1 - 2.6 7.7 55.1 0.054 13.2 30.4 3.1 1 1 2 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease Ax_dynein_light PF10211.9 CBY43548.1 - 2.6 8.0 53.4 0.19 11.6 14.9 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain TACC_C PF05010.14 CBY43548.1 - 2.6 7.8 48.8 6.7 6.4 30.1 3.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 CBY43548.1 - 3.7 6.9 52.3 0.15 11.4 15.0 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 CBY43548.1 - 4 7.6 38.6 0.093 12.8 10.3 5.2 2 1 3 5 5 4 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 CBY43548.1 - 4.2 7.6 41.8 6 7.1 9.3 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 CBY43548.1 - 6.7 7.1 56.0 0.69 10.3 17.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 CBY43548.1 - 7.4 6.8 42.4 0.16 12.1 2.7 5.8 2 1 2 5 5 4 0 bZIP transcription factor ADIP PF11559.8 CBY43548.1 - 9.3 6.3 51.7 0.58 10.2 20.8 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5451 PF17532.2 CBY43549.1 - 0.00061 20.1 3.4 0.0007 19.9 3.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5451) UQ_con PF00179.26 CBY43552.1 - 1.9e-47 160.4 0.0 2.1e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBY43552.1 - 2.5e-06 27.2 0.0 3.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase_Tyr PF07714.17 CBY43554.1 - 1e-85 287.2 0.7 1.2e-85 287.0 0.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CBY43554.1 - 4.4e-43 147.5 0.4 5.8e-43 147.1 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CBY43554.1 - 0.0087 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBY43554.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 CBY43554.1 - 0.039 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ins145_P3_rec PF08709.11 CBY43554.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF3361 PF11841.8 CBY43556.1 - 0.0097 15.9 0.5 0.072 13.0 0.1 2.4 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) CUE PF02845.16 CBY43557.1 - 4.7e-06 26.2 0.1 8.9e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 CUE domain Galactosyl_T PF01762.21 CBY43558.1 - 0.00049 20.0 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase LIN37 PF15306.6 CBY43558.1 - 0.025 14.8 1.6 0.037 14.3 1.6 1.2 1 0 0 1 1 1 0 LIN37 Homeodomain PF00046.29 CBY43559.1 - 3.1e-13 49.4 0.7 6e-13 48.4 0.7 1.5 1 0 0 1 1 1 1 Homeodomain Glyco_hydro_15 PF00723.21 CBY43561.1 - 1.8e-10 40.2 0.0 2.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF4600 PF15372.6 CBY43562.1 - 1.9e-37 128.5 21.7 3.5e-37 127.7 10.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4600) Prominin PF05478.11 CBY43562.1 - 0.15 10.0 10.1 0.19 9.7 10.1 1.2 1 0 0 1 1 1 0 Prominin YscO-like PF16789.5 CBY43562.1 - 0.16 12.0 18.6 1.5 8.9 9.9 2.3 2 0 0 2 2 2 0 YscO-like protein Spc7 PF08317.11 CBY43562.1 - 0.39 9.6 24.2 0.38 9.6 23.0 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 CBY43562.1 - 0.43 9.8 19.8 0.039 13.3 14.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PI_PP_I PF18363.1 CBY43562.1 - 0.8 9.9 6.7 0.25 11.5 2.6 2.1 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain ARGLU PF15346.6 CBY43562.1 - 1.5 8.7 27.3 2.8 7.8 5.5 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 RyR PF02026.16 CBY43562.1 - 3.9 7.7 9.0 0.41 10.9 1.2 2.3 2 0 0 2 2 2 0 RyR domain Macoilin PF09726.9 CBY43562.1 - 4.1 5.8 27.1 0.77 8.2 23.7 1.5 1 1 0 1 1 1 0 Macoilin family BRE1 PF08647.11 CBY43562.1 - 4.6 7.4 28.5 0.66 10.1 15.7 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Sec20 PF03908.13 CBY43562.1 - 5 7.1 8.6 3.6 7.6 4.9 2.4 1 1 1 2 2 2 0 Sec20 THOC7 PF05615.13 CBY43562.1 - 5.2 7.4 23.3 0.13 12.6 14.6 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.6 CBY43562.1 - 7.1 5.9 21.3 17 4.7 21.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2748 PF10871.8 CBY43562.1 - 7.8 5.0 11.0 1 7.9 4.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2748) Histone PF00125.24 CBY43564.1 - 1.7e-21 76.9 0.5 2.2e-21 76.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBY43564.1 - 5.6e-07 29.8 0.1 1.3e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CBY43564.1 - 5e-05 23.7 0.0 9.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CBY43564.1 - 0.00078 19.5 0.2 0.00088 19.3 0.2 1.1 1 0 0 1 1 1 1 YscO-like protein CENP-W PF15510.6 CBY43564.1 - 0.039 14.2 0.8 0.11 12.8 0.8 1.7 1 1 0 1 1 1 0 CENP-W protein Pih1_fungal_CS PF18482.1 CBY43566.1 - 0.0032 18.0 0.0 0.0039 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal Pih1 CS domain Zip PF02535.22 CBY43567.1 - 2e-18 66.7 6.1 5.5e-10 39.0 1.0 3.1 1 1 2 3 3 3 2 ZIP Zinc transporter CENP-B_dimeris PF09026.10 CBY43567.1 - 0.0046 17.3 12.7 0.21 12.0 12.5 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Nop14 PF04147.12 CBY43567.1 - 0.024 12.9 1.9 0.037 12.3 1.9 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 CBY43567.1 - 0.53 8.8 2.5 0.76 8.2 2.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CBY43567.1 - 0.64 8.1 12.1 1.3 7.1 12.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CBY43567.1 - 1.6 8.4 5.8 1.7 8.3 3.7 2.0 2 0 0 2 2 2 0 FAM176 family DUF2796 PF10986.8 CBY43567.1 - 1.7 8.6 18.3 16 5.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) RXT2_N PF08595.11 CBY43567.1 - 4.9 7.2 8.3 8.5 6.4 6.8 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.14 CBY43567.1 - 5.2 5.2 7.9 8.3 4.6 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein ANAPC4_WD40 PF12894.7 CBY43569.1 - 0.0074 16.6 0.4 3.8 7.9 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBY43569.1 - 0.036 13.4 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 WD40-like domain Hira PF07569.11 CBY43569.1 - 0.036 13.8 0.3 0.042 13.6 0.3 1.3 1 1 0 1 1 1 0 TUP1-like enhancer of split Dcc1 PF09724.9 CBY43570.1 - 2.7e-56 191.3 1.0 3.3e-56 191.0 1.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 SMC_ScpB PF04079.16 CBY43570.1 - 0.066 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB zf-C2H2 PF00096.26 CBY43571.1 - 8.7e-11 41.7 14.7 0.00014 22.1 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBY43571.1 - 6.7e-09 35.8 15.9 0.004 17.9 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CBY43571.1 - 9.3e-07 29.0 16.7 0.0031 17.9 3.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain CpXC PF14353.6 CBY43571.1 - 9.1e-05 22.5 11.3 0.83 9.7 2.7 3.6 1 1 1 2 2 2 2 CpXC protein zf_UBZ PF18439.1 CBY43571.1 - 0.0019 17.7 7.3 2.1 8.0 0.3 3.8 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CBY43571.1 - 0.0025 17.6 5.0 1.9 8.3 0.3 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CBY43571.1 - 0.0041 17.1 2.1 0.0041 17.1 2.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 CBY43571.1 - 0.0069 16.3 11.4 0.27 11.2 0.4 3.8 2 1 1 3 3 3 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CBY43571.1 - 0.0087 15.6 0.5 5.5 6.6 0.5 3.4 2 1 0 2 2 2 1 TFIIB zinc-binding RNHCP PF12647.7 CBY43571.1 - 0.016 15.1 7.0 0.89 9.6 0.2 3.6 3 0 0 3 3 3 0 RNHCP domain CxC5 PF18718.1 CBY43571.1 - 0.024 14.7 8.9 4.3 7.4 1.1 3.5 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases LIM PF00412.22 CBY43571.1 - 0.043 14.1 15.4 2.5 8.4 6.2 3.4 1 1 1 2 2 2 0 LIM domain zf-C2H2_jaz PF12171.8 CBY43571.1 - 0.051 13.9 2.4 0.051 13.9 2.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.6 CBY43571.1 - 0.06 13.1 11.8 0.31 10.8 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.7 CBY43571.1 - 0.063 13.7 1.5 0.063 13.7 1.5 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_2 PF13240.6 CBY43571.1 - 0.094 12.5 4.9 2 8.2 0.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 CBY43571.1 - 0.095 12.7 8.0 0.3 11.2 0.1 3.3 2 1 1 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 CBY43571.1 - 0.11 12.5 10.4 0.19 11.7 3.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBY43571.1 - 0.19 11.9 11.8 6.3 7.0 0.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain RMI1_C PF16099.5 CBY43571.1 - 0.23 11.3 3.3 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Recq-mediated genome instability protein 1, C-terminal OB-fold XPA_N PF01286.18 CBY43571.1 - 0.54 10.3 11.7 6.3 6.9 1.5 3.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_8 PF15909.5 CBY43571.1 - 0.99 9.7 12.0 6.1 7.2 10.0 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zinc-ribbons_6 PF07191.12 CBY43571.1 - 1.5 8.8 10.4 13 5.9 4.1 2.9 1 1 1 2 2 2 0 zinc-ribbons ADK_lid PF05191.14 CBY43571.1 - 3.5 7.7 8.2 21 5.2 0.1 3.2 2 1 0 2 2 2 0 Adenylate kinase, active site lid C1_4 PF07975.12 CBY43571.1 - 3.8 7.8 11.5 22 5.4 0.3 3.2 2 1 1 3 3 3 0 TFIIH C1-like domain HypA PF01155.19 CBY43571.1 - 3.8 7.6 12.8 2.2 8.4 2.0 2.8 2 1 2 4 4 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_12 PF11331.8 CBY43571.1 - 5 7.0 8.1 7.4 6.5 0.1 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-ACC PF17848.1 CBY43571.1 - 5.3 7.2 9.4 5.3 7.2 0.3 3.8 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain IF4E PF01652.18 CBY43572.1 - 1.1e-39 135.7 0.1 1.4e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_2 PF02230.16 CBY43573.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HIN PF02760.15 CBY43573.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 HIN-200/IF120x domain LRR_8 PF13855.6 CBY43576.1 - 7.4e-09 35.2 20.4 4.2e-05 23.2 8.5 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBY43576.1 - 7.5e-08 32.6 27.5 0.0012 19.2 3.5 4.1 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBY43576.1 - 0.0056 16.6 11.8 6.6 7.1 0.0 4.7 4 0 0 4 4 4 3 Leucine Rich repeat RIIa PF02197.17 CBY43576.1 - 0.025 14.2 0.1 0.74 9.5 0.0 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit LRR_9 PF14580.6 CBY43576.1 - 0.079 12.5 10.9 0.54 9.7 2.3 2.7 1 1 2 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 CBY43576.1 - 0.11 13.1 22.7 4.3 8.3 0.0 6.1 5 1 0 5 5 5 0 Leucine Rich Repeat RE_ScaI PF09569.10 CBY43577.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 ScaI restriction endonuclease XRN1_D2_D3 PF18334.1 CBY43578.1 - 0.022 15.0 0.1 0.24 11.6 0.0 2.7 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D2/D3 domain HflK_N PF12221.8 CBY43578.1 - 0.16 12.0 0.0 18 5.4 0.0 3.5 4 0 0 4 4 4 0 Bacterial membrane protein N terminal Hormone_recep PF00104.30 CBY43579.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Na_H_Exchanger PF00999.21 CBY43581.1 - 1.1e-47 162.7 16.4 1.4e-47 162.4 16.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hydrolase_4 PF12146.8 CBY43582.1 - 3.7e-08 32.9 0.0 0.0039 16.5 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBY43582.1 - 3.3e-06 26.9 0.0 0.046 13.3 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY43582.1 - 1.4e-05 24.7 0.0 0.0064 16.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF818 PF05677.12 CBY43582.1 - 0.00035 19.7 0.1 0.00063 18.8 0.1 1.4 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 CBY43582.1 - 0.00059 20.5 0.0 0.0013 19.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp2 PF16929.5 CBY43582.1 - 0.0025 16.9 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter DLH PF01738.18 CBY43582.1 - 0.0029 17.2 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1057 PF06342.12 CBY43582.1 - 0.0069 15.5 0.0 0.0079 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 CBY43582.1 - 0.0071 16.2 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBY43582.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Trypsin PF00089.26 CBY43583.1 - 1.9e-27 96.5 0.2 2.3e-27 96.3 0.2 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY43583.1 - 0.00012 23.0 0.0 0.0002 22.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain RRM_1 PF00076.22 CBY43585.1 - 1.3e-09 37.7 0.2 5.9e-09 35.6 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY43585.1 - 0.0037 17.4 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Peptidase_A22B PF04258.13 CBY43587.1 - 0.012 15.1 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Signal peptide peptidase Herpes_UL25 PF01499.16 CBY43587.1 - 0.28 9.6 1.1 11 4.4 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL25 family Dynamin_M PF01031.20 CBY43588.1 - 0.072 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region Lactamase_B_6 PF16661.5 CBY43589.1 - 6.9e-23 81.1 0.0 1.2e-22 80.3 0.0 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CBY43589.1 - 4.6e-13 49.6 1.1 2.5e-09 37.4 0.2 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBY43589.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CBY43589.1 - 2.1e-06 27.1 0.0 4.9e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 CBY43589.1 - 1.7e-05 24.8 0.0 5.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 CBY43589.1 - 0.013 14.7 0.1 0.021 14.0 0.1 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Acyl-CoA_dh_M PF02770.19 CBY43590.1 - 2.2e-26 91.9 0.0 3.6e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBY43590.1 - 2.8e-26 92.4 0.0 4.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CBY43590.1 - 2.1e-07 31.3 0.2 3.2e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBY43590.1 - 0.014 16.0 0.0 0.05 14.1 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Piwi PF02171.17 CBY43591.1 - 6.6e-42 143.8 0.0 9.5e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 CBY43591.1 - 7.5e-09 35.5 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CBY43591.1 - 0.00023 21.4 0.0 0.002 18.4 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 CBY43591.1 - 0.00058 20.1 0.0 0.0025 18.0 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute bZIP_1 PF00170.21 CBY43595.1 - 0.043 13.9 4.5 0.043 13.9 4.5 4.5 3 1 1 4 4 4 0 bZIP transcription factor DUF4758 PF15950.5 CBY43595.1 - 0.046 14.1 5.7 0.072 13.4 5.7 1.5 1 1 0 1 1 1 0 Putative sperm flagellar membrane protein Prominin PF05478.11 CBY43595.1 - 0.17 9.8 13.0 0.21 9.5 13.0 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 CBY43595.1 - 0.9 8.8 15.4 1.2 8.4 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 CBY43595.1 - 1.5 8.5 10.5 0.15 11.8 3.2 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Neur_chan_memb PF02932.16 CBY43595.1 - 1.7 8.6 8.1 2.4 8.1 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM192 PF14802.6 CBY43595.1 - 4.1 6.4 6.6 0.28 10.3 0.8 1.8 2 0 0 2 2 2 0 TMEM192 family Golgin_A5 PF09787.9 CBY43595.1 - 4.3 6.7 31.6 0.89 9.0 21.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 CBY43595.1 - 5.3 6.4 34.6 15 4.9 34.6 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GAGA_bind PF06217.12 CBY43595.1 - 5.6 7.2 11.8 7.3 6.8 11.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF724 PF05266.14 CBY43595.1 - 5.6 6.7 31.6 6.6 6.5 12.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Cupin_8 PF13621.6 CBY43595.1 - 6.8 6.3 8.1 13 5.4 7.8 1.6 1 1 0 1 1 1 0 Cupin-like domain Spc7 PF08317.11 CBY43595.1 - 9.3 5.0 28.3 15 4.4 28.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-TAZ PF02135.16 CBY43596.1 - 6.8 7.2 9.8 6.4e+02 0.9 9.8 2.2 1 1 0 1 1 1 0 TAZ zinc finger RNA_pol_Rpb1_6 PF04992.14 CBY43597.1 - 9e-64 214.8 2.4 1.5e-63 214.1 2.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_5 PF04998.17 CBY43597.1 - 5.2e-63 213.0 0.0 6.2e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 CBY43597.1 - 3.3e-53 179.3 2.4 1e-52 177.7 2.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 EutB PF06751.11 CBY43597.1 - 0.012 14.4 0.1 0.021 13.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) TED_complement PF07678.14 CBY43598.1 - 2.1e-12 46.7 0.0 2.4e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 A-macroglobulin TED domain CLPTM1 PF05602.12 CBY43599.1 - 1.4e-83 281.3 0.2 2.9e-83 280.3 0.2 1.4 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) COesterase PF00135.28 CBY43601.1 - 2.3e-62 211.5 0.3 2.9e-62 211.2 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY43601.1 - 1.2e-09 38.3 1.1 2.4e-05 24.3 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Poxvirus_B22R_C PF13168.6 CBY43603.1 - 0.046 13.2 0.2 0.049 13.1 0.2 1.0 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal C1_1 PF00130.22 CBY43607.1 - 7.9e-17 60.9 4.7 1.1e-16 60.4 4.7 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CBY43607.1 - 0.021 14.9 1.6 0.043 13.9 1.6 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger C1_2 PF03107.16 CBY43607.1 - 0.039 14.3 3.4 0.071 13.4 3.4 1.5 1 0 0 1 1 1 0 C1 domain PPP5 PF08321.12 CBY43607.1 - 0.057 13.7 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 PPP5 TPR repeat region PHD PF00628.29 CBY43607.1 - 0.073 13.0 4.5 0.14 12.1 4.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 CBY43607.1 - 0.08 12.9 1.9 0.12 12.3 1.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 CBY43607.1 - 0.15 12.4 4.9 0.29 11.5 4.9 1.5 1 0 0 1 1 1 0 RING-like domain ADK_lid PF05191.14 CBY43607.1 - 0.5 10.4 4.7 8 6.5 2.6 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid Cwf_Cwc_15 PF04889.12 CBY43608.1 - 3.8 7.2 8.3 6.2 6.5 8.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PCNP PF15473.6 CBY43609.1 - 2.1 9.1 6.8 0.33 11.7 2.1 2.0 2 1 0 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family Profilin PF00235.19 CBY43610.1 - 2.1e-24 86.2 0.2 2.3e-24 86.1 0.2 1.0 1 0 0 1 1 1 1 Profilin SH3_9 PF14604.6 CBY43611.1 - 2.6e-11 43.2 0.1 6.2e-11 42.0 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBY43611.1 - 1.2e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBY43611.1 - 2.7e-05 23.7 0.1 0.00022 20.8 0.1 2.1 1 1 0 1 1 1 1 SH3 domain hSH3 PF14603.6 CBY43611.1 - 0.012 16.0 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 Helically-extended SH3 domain dCMP_cyt_deam_1 PF00383.23 CBY43613.1 - 4e-14 52.3 0.1 7e-14 51.5 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBY43613.1 - 7.5e-07 29.4 0.1 1e-06 29.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DnaJ PF00226.31 CBY43614.1 - 1e-09 38.3 1.0 1.9e-08 34.3 0.4 2.6 2 1 0 2 2 2 1 DnaJ domain EMP70 PF02990.16 CBY43615.1 - 8.7e-105 351.3 34.2 8.7e-105 351.3 34.2 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 PMP22_Claudin PF00822.20 CBY43616.1 - 1.3e-15 57.6 0.3 1.4e-15 57.6 0.3 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Sensor PF13796.6 CBY43616.1 - 0.012 15.6 0.1 0.014 15.5 0.1 1.1 1 0 0 1 1 1 0 Putative sensor Clc-like PF07062.12 CBY43616.1 - 0.053 13.0 0.4 0.071 12.6 0.0 1.4 2 0 0 2 2 2 0 Clc-like KH_1 PF00013.29 CBY43618.1 - 1.3e-39 133.9 6.4 5e-14 51.9 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CBY43618.1 - 1.4e-11 44.1 8.5 0.0037 17.0 2.8 3.7 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 CBY43618.1 - 4e-05 23.4 4.8 0.029 14.2 0.0 3.9 4 1 0 4 4 4 2 KH domain DUF3420 PF11900.8 CBY43618.1 - 8.7e-05 22.6 0.4 0.16 12.1 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3420) SLS PF14611.6 CBY43618.1 - 0.028 14.3 2.7 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator GPW_gp25 PF04965.14 CBY43618.1 - 0.062 13.1 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Gene 25-like lysozyme MOEP19 PF16005.5 CBY43618.1 - 0.088 12.8 0.0 5.3 7.1 0.0 2.6 3 0 0 3 3 3 0 KH-like RNA-binding domain KH_5 PF13184.6 CBY43618.1 - 0.13 12.3 2.6 4.6 7.4 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain Dimer_Tnp_hAT PF05699.14 CBY43619.1 - 0.00075 19.2 0.1 0.0031 17.3 0.1 1.8 1 1 1 2 2 2 2 hAT family C-terminal dimerisation region Tfb2_C PF18307.1 CBY43619.1 - 0.047 14.1 0.1 0.076 13.4 0.0 1.4 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain DUF2724 PF10893.8 CBY43620.1 - 0.038 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) EGF_CA PF07645.15 CBY43621.1 - 3.7e-161 523.1 427.9 1.9e-10 40.8 11.7 25.2 25 3 0 25 25 25 22 Calcium-binding EGF domain EGF_3 PF12947.7 CBY43621.1 - 5.9e-106 346.4 365.5 3.8e-08 33.4 8.3 23.7 23 0 0 23 23 23 22 EGF domain cEGF PF12662.7 CBY43621.1 - 4.1e-83 272.8 240.9 8.7e-08 32.0 4.7 24.3 23 0 0 23 23 23 22 Complement Clr-like EGF-like EGF PF00008.27 CBY43621.1 - 1.8e-31 108.0 315.8 0.0015 18.8 7.9 24.8 24 1 0 24 24 24 19 EGF-like domain hEGF PF12661.7 CBY43621.1 - 3.1e-15 56.2 304.8 0.0031 18.1 2.8 27.0 28 1 0 28 28 28 17 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY43621.1 - 1.5e-13 50.5 298.0 0.0005 20.1 4.5 22.6 22 1 1 23 23 23 15 MSP1 EGF domain 1 Cadherin PF00028.17 CBY43622.1 - 1.7e-15 57.2 0.1 1.6e-05 25.3 0.1 3.8 4 0 0 4 4 4 3 Cadherin domain CcmH PF03918.14 CBY43623.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PhyH PF05721.13 CBY43624.1 - 1.9e-65 221.0 0.3 2.3e-65 220.8 0.3 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Asp_Arg_Hydrox PF05118.15 CBY43624.1 - 0.007 16.2 1.2 0.14 12.0 0.0 2.7 3 0 0 3 3 3 1 Aspartyl/Asparaginyl beta-hydroxylase SAM_2 PF07647.17 CBY43625.1 - 0.001 19.1 0.1 0.0024 17.9 0.1 1.6 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) Med26_C PF15693.5 CBY43627.1 - 2.1e-09 37.8 0.8 1.1e-08 35.5 0.8 2.3 1 1 0 1 1 1 1 Mediator complex subunit 26 C-terminal CytochromB561_N PF09786.9 CBY43627.1 - 0.085 11.8 11.0 0.097 11.7 11.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Kelch_1 PF01344.25 CBY43628.1 - 3e-34 116.4 3.6 2.2e-14 52.7 0.0 3.0 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CBY43628.1 - 7.3e-20 70.5 1.0 3.4e-09 36.7 0.1 3.0 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CBY43628.1 - 1.6e-09 37.3 3.2 0.0064 16.4 0.1 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CBY43628.1 - 1.7e-06 28.0 1.9 0.00079 19.4 0.0 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY43628.1 - 8.7e-06 25.9 0.8 0.043 14.1 0.5 2.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY43628.1 - 0.0014 18.6 0.1 0.63 10.1 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CBY43629.1 - 1.7e-69 229.2 4.9 1.7e-15 56.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBY43629.1 - 1.3e-39 133.2 2.0 3.8e-08 33.3 0.1 6.3 5 1 1 6 6 6 6 Kelch motif BTB PF00651.31 CBY43629.1 - 3.1e-30 104.6 1.2 6e-30 103.7 1.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CBY43629.1 - 4.3e-26 91.0 0.3 1.1e-25 89.7 0.3 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 CBY43629.1 - 6.8e-21 73.4 3.9 3.6e-06 26.7 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CBY43629.1 - 1.8e-19 69.4 6.5 1.3e-05 25.0 0.0 6.2 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBY43629.1 - 1.6e-15 56.9 2.8 0.0015 18.7 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBY43629.1 - 5.9e-08 32.5 2.2 3.1 7.9 0.0 6.1 6 0 0 6 6 6 3 Kelch motif DUF3342 PF11822.8 CBY43629.1 - 0.0022 18.2 1.4 0.0059 16.8 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Glyoxal_oxid_N PF07250.11 CBY43629.1 - 0.03 13.5 0.0 0.062 12.5 0.0 1.6 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 CBY43629.1 - 0.75 10.4 3.4 65 4.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain TLD PF07534.16 CBY43630.1 - 7.7e-12 45.6 0.1 1.2e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 CBY43630.1 - 0.015 15.0 0.5 0.039 13.6 0.5 1.7 1 1 0 1 1 1 0 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 CBY43632.1 - 0.017 15.0 0.3 1.8 8.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain WD40 PF00400.32 CBY43633.1 - 3.6e-11 43.4 0.0 7.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY43633.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1979 PF09322.10 CBY43633.1 - 0.042 13.8 0.2 0.084 12.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1979) SNARE PF05739.19 CBY43634.1 - 0.0015 18.5 0.1 0.0027 17.7 0.1 1.5 1 0 0 1 1 1 1 SNARE domain DUF16 PF01519.16 CBY43634.1 - 0.0017 18.8 2.8 0.0019 18.7 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF16 UPF0242 PF06785.11 CBY43634.1 - 0.14 12.3 5.6 0.17 12.0 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ran_BP1 PF00638.18 CBY43635.1 - 1.2e-10 41.7 0.1 1.2e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain IPPT PF01715.17 CBY43636.1 - 1.7e-41 142.5 0.0 2.2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 CBY43636.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 CBY43636.1 - 0.00035 20.8 0.1 0.0045 17.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBY43636.1 - 0.011 16.2 0.0 0.044 14.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBY43636.1 - 0.013 16.0 0.2 0.22 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 CBY43636.1 - 0.016 15.3 0.1 5.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Hpr_kinase_C PF07475.12 CBY43636.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain IstB_IS21 PF01695.17 CBY43636.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein baeRF_family3 PF18845.1 CBY43636.1 - 0.11 12.8 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 ABC_tran PF00005.27 CBY43636.1 - 0.12 12.9 0.1 0.26 11.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter LRR_4 PF12799.7 CBY43637.1 - 4.1e-25 87.4 30.0 9.5e-08 32.2 3.0 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBY43637.1 - 6.8e-25 86.6 24.3 4.2e-09 36.0 1.9 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 CBY43637.1 - 1.4e-06 28.0 24.0 2.3 9.1 0.4 7.7 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 CBY43637.1 - 8e-06 25.5 15.9 0.0032 17.0 2.7 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBY43637.1 - 0.0014 18.5 28.0 0.34 11.1 1.8 6.8 7 0 0 7 7 7 3 Leucine Rich repeat zf_CopZ PF18423.1 CBY43637.1 - 0.092 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain CENP-F_leu_zip PF10473.9 CBY43638.1 - 0.00049 20.1 23.6 0.00049 20.1 23.6 9.3 3 2 5 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CBY43638.1 - 0.0008 19.9 23.8 0.0008 19.9 23.8 9.0 2 2 6 8 8 8 2 Apg6 coiled-coil region Cast PF10174.9 CBY43638.1 - 3.1 5.9 151.7 0.15 10.3 36.6 5.0 2 1 2 4 4 4 0 RIM-binding protein of the cytomatrix active zone FYVE PF01363.21 CBY43639.1 - 2.9e-14 53.0 7.7 6.1e-14 51.9 7.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.32 CBY43639.1 - 6.5e-14 52.1 8.7 1.4e-06 28.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY43639.1 - 1.3e-06 28.6 0.2 0.056 13.7 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_9 PF13901.6 CBY43639.1 - 0.0012 18.9 2.0 0.0025 17.8 2.0 1.5 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Nucleoporin_N PF08801.11 CBY43639.1 - 0.008 15.0 0.7 0.074 11.8 0.1 2.7 3 0 0 3 3 3 1 Nup133 N terminal like DUF326 PF03860.16 CBY43639.1 - 1.1 9.3 9.3 12 6.0 9.1 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF326) PSP94 PF05825.11 CBY43640.1 - 0.0003 21.3 7.8 0.00054 20.5 7.8 1.4 1 1 0 1 1 1 1 Beta-microseminoprotein (PSP-94) DUF4802 PF16060.5 CBY43640.1 - 0.042 14.0 3.4 0.089 13.0 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) MoCF_biosynth PF00994.24 CBY43642.1 - 1.5e-29 102.5 0.0 4.2e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 CBY43642.1 - 1.5e-23 83.8 0.1 3.5e-21 76.0 0.1 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF1609 PF07753.11 CBY43642.1 - 0.0033 17.0 0.2 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1609) DUF3164 PF11363.8 CBY43642.1 - 0.004 16.8 0.3 0.25 10.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) DZF PF07528.14 CBY43644.1 - 5.9e-42 144.0 0.0 9.8e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 DZF domain dsrm PF00035.26 CBY43644.1 - 1.3e-14 54.6 5.1 3.4e-06 27.7 0.2 3.6 3 0 0 3 3 3 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CBY43644.1 - 1.1e-05 25.5 6.9 0.081 13.1 0.0 4.4 4 0 0 4 4 4 2 Dicer dimerisation domain SIKE PF05769.11 CBY43644.1 - 0.077 12.9 0.4 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 SIKE family Dynein_light PF01221.18 CBY43644.1 - 0.28 11.5 1.9 1.8 8.9 0.0 3.1 3 0 0 3 3 3 0 Dynein light chain type 1 Iso_dh PF00180.20 CBY43645.1 - 2.8e-105 352.3 0.0 3.2e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sulfatase PF00884.23 CBY43646.1 - 1.2e-48 166.1 0.1 1.6e-48 165.7 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CBY43646.1 - 0.025 15.3 0.0 0.041 14.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase SMAP PF15477.6 CBY43647.1 - 0.057 14.4 0.1 0.057 14.4 0.1 3.0 3 0 0 3 3 3 0 Small acidic protein family TEX19 PF15553.6 CBY43647.1 - 1.1 9.2 10.8 0.66 9.9 6.8 2.5 1 1 1 2 2 2 0 Testis-expressed protein 19 Apolipoprotein PF01442.18 CBY43648.1 - 0.0029 17.5 4.8 0.0029 17.5 4.8 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain An_peroxidase PF03098.15 CBY43648.1 - 0.019 13.6 0.4 0.034 12.7 0.4 1.3 1 0 0 1 1 1 0 Animal haem peroxidase Vps39_2 PF10367.9 CBY43648.1 - 0.33 11.4 3.1 19 5.8 0.0 3.5 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 Med19 PF10278.9 CBY43649.1 - 1.7e-12 47.6 0.9 1.7e-12 47.6 0.9 2.1 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 DAG_kinase_N PF14513.6 CBY43649.1 - 0.01 16.1 4.2 0.028 14.6 4.2 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase N-terminus SR-25 PF10500.9 CBY43649.1 - 0.07 12.7 13.1 0.084 12.5 13.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CBY43649.1 - 0.1 13.3 12.0 0.14 12.8 12.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Far-17a_AIG1 PF04750.14 CBY43650.1 - 1.3e-08 34.4 1.4 1.8e-08 33.9 1.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.14 CBY43652.1 - 4.1e-19 68.7 6.9 4.1e-19 68.7 6.9 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein His_Phos_2 PF00328.22 CBY43653.1 - 8.5e-29 101.1 1.7 5.7e-26 91.8 1.7 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CDH1_2_SANT_HL1 PF18375.1 CBY43653.1 - 0.047 14.4 0.1 0.11 13.2 0.0 1.6 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Complex1_LYR PF05347.15 CBY43654.1 - 5.1e-06 26.4 0.5 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBY43654.1 - 0.077 13.7 1.2 0.11 13.2 1.2 1.3 1 0 0 1 1 1 0 Complex1_LYR-like HATPase_c_3 PF13589.6 CBY43655.1 - 5.5e-17 61.9 0.1 1.8e-16 60.2 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Morc6_S5 PF17942.1 CBY43655.1 - 2.3e-09 37.4 6.5 0.00051 20.1 0.0 3.2 4 0 0 4 4 4 2 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 CBY43655.1 - 4.9e-05 23.3 3.1 0.00057 19.9 2.4 2.5 2 0 0 2 2 2 1 CW-type Zinc Finger CBM64 PF18666.1 CBY43655.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 64 FlxA PF14282.6 CBY43655.1 - 0.13 12.2 7.6 0.37 10.8 0.2 3.2 3 0 0 3 3 3 0 FlxA-like protein CENP-F_leu_zip PF10473.9 CBY43655.1 - 1 9.3 19.3 0.024 14.6 2.4 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 CBY43655.1 - 1.5 9.1 24.6 1.1 9.6 7.9 4.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RhoGAP PF00620.27 CBY43656.1 - 6.5e-34 117.0 0.4 1.4e-33 115.9 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain PH_9 PF15410.6 CBY43656.1 - 1e-10 42.0 0.0 3.1e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CBY43656.1 - 7.9e-07 29.5 2.7 1e-06 29.2 0.0 2.5 3 0 0 3 3 3 1 PH domain Serglycin PF04360.12 CBY43656.1 - 0.027 14.4 1.4 0.091 12.7 0.4 2.3 2 0 0 2 2 2 0 Serglycin Chlam_OMP3 PF03503.13 CBY43656.1 - 0.053 13.8 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Sushi PF00084.20 CBY43657.1 - 7.1e-06 26.5 7.3 0.037 14.6 0.2 3.5 3 1 0 3 3 3 2 Sushi repeat (SCR repeat) MAM PF00629.23 CBY43657.1 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 MAM domain, meprin/A5/mu DUF2681 PF10883.8 CBY43657.1 - 1 9.8 2.9 3.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) 7tm_1 PF00001.21 CBY43658.1 - 1.4e-07 31.1 4.7 1.4e-07 31.1 4.7 2.8 2 2 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) PKD_channel PF08016.12 CBY43658.1 - 0.0049 15.6 0.4 0.011 14.4 0.4 1.5 1 0 0 1 1 1 1 Polycystin cation channel 7TM_GPCR_Srsx PF10320.9 CBY43658.1 - 0.0052 16.2 14.5 0.018 14.5 9.8 2.9 2 1 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx RIFIN PF02009.16 CBY43658.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Rifin zf-Tim10_DDP PF02953.15 CBY43659.1 - 5.5e-11 42.0 2.2 9.8e-11 41.2 2.2 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_6 PF12697.7 CBY43660.1 - 0.01 16.4 0.0 0.01 16.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nup84_Nup100 PF04121.13 CBY43661.1 - 8.4e-63 212.6 10.1 4.6e-61 206.9 10.2 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 THUMP PF02926.17 CBY43661.1 - 0.031 14.4 0.1 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 THUMP domain ANAPC4_WD40 PF12894.7 CBY43662.1 - 9.8e-14 51.4 0.0 1.3e-10 41.5 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBY43662.1 - 2.3e-05 25.0 0.0 42 5.2 0.0 6.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CBY43662.1 - 3.1e-05 23.2 6.0 0.00016 20.9 0.1 3.6 4 0 0 4 4 4 1 Coatomer WD associated region PD40 PF07676.12 CBY43662.1 - 0.00065 19.6 0.0 0.28 11.2 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat TPR_7 PF13176.6 CBY43662.1 - 0.037 14.1 2.3 8.3 6.7 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF758 PF05527.11 CBY43663.1 - 6e-45 153.4 1.1 6.8e-45 153.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF758) CorA PF01544.18 CBY43663.1 - 0.065 12.5 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb4 PF03874.16 CBY43664.1 - 4.8e-25 88.3 0.5 6.8e-25 87.8 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 MCM PF00493.23 CBY43665.1 - 4.7e-93 310.4 0.1 8.1e-93 309.6 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBY43665.1 - 1.5e-30 105.6 0.3 3.1e-30 104.6 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBY43665.1 - 4.2e-22 78.4 1.8 4.2e-22 78.4 1.8 2.2 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBY43665.1 - 2.1e-10 41.1 0.0 8.3e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBY43665.1 - 3.7e-07 29.7 0.0 2.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBY43665.1 - 0.0072 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DivIC PF04977.15 CBY43665.1 - 0.033 13.9 8.4 0.73 9.6 2.5 4.3 3 1 1 4 4 4 0 Septum formation initiator DUF4201 PF13870.6 CBY43665.1 - 0.048 13.4 17.5 0.12 12.1 17.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_5 PF07728.14 CBY43665.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Csm1_N PF18504.1 CBY43665.1 - 0.34 11.3 14.8 0.62 10.4 2.9 3.2 1 1 1 2 2 2 0 Csm1 N-terminal domain Peptidase_M2 PF01401.18 CBY43665.1 - 0.81 8.2 7.2 1.6 7.3 7.2 1.4 1 0 0 1 1 1 0 Angiotensin-converting enzyme TMPIT PF07851.13 CBY43665.1 - 5 6.3 9.9 11 5.2 9.9 1.6 1 0 0 1 1 1 0 TMPIT-like protein Leu_zip PF15294.6 CBY43665.1 - 5.7 6.4 21.7 0.09 12.3 14.0 1.8 2 0 0 2 2 2 0 Leucine zipper CNOT11 PF10155.9 CBY43666.1 - 8.5e-42 142.3 1.2 1.8e-41 141.2 1.2 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 YihI PF04220.12 CBY43666.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) EGF_CA PF07645.15 CBY43667.1 - 3e-59 197.0 126.0 1.8e-10 40.8 11.2 8.4 9 0 0 9 9 9 7 Calcium-binding EGF domain cEGF PF12662.7 CBY43667.1 - 1.1e-30 105.2 49.8 7.4e-07 29.0 3.3 8.6 8 0 0 8 8 8 7 Complement Clr-like EGF-like EGF_3 PF12947.7 CBY43667.1 - 7.7e-15 54.8 109.6 0.00045 20.4 6.3 8.5 7 1 2 9 9 9 7 EGF domain hEGF PF12661.7 CBY43667.1 - 1.2e-06 28.9 68.5 0.013 16.2 1.5 10.2 10 0 0 10 10 10 5 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 CBY43667.1 - 0.00088 19.3 70.7 0.021 14.9 7.0 8.0 7 0 0 7 7 7 4 MSP1 EGF domain 1 FXa_inhibition PF14670.6 CBY43667.1 - 0.0021 18.3 110.7 0.089 13.1 11.1 8.3 8 0 0 8 8 8 6 Coagulation Factor Xa inhibitory site FGF PF00167.18 CBY43668.1 - 5e-14 52.5 0.3 5.2e-14 52.4 0.3 1.0 1 0 0 1 1 1 1 Fibroblast growth factor zf-C2H2 PF00096.26 CBY43669.1 - 4.1e-05 23.8 6.0 0.0044 17.4 1.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 CBY43669.1 - 0.001 19.4 5.0 0.0097 16.3 0.7 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBY43669.1 - 0.011 16.0 5.4 1.7 9.0 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBY43669.1 - 0.018 15.5 1.5 0.018 15.5 1.5 3.0 2 1 1 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CBY43669.1 - 0.031 15.1 0.2 0.031 15.1 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger EGF_2 PF07974.13 CBY43670.1 - 0.053 13.9 2.9 0.053 13.9 2.9 3.4 2 1 0 2 2 2 0 EGF-like domain MamL-1 PF09596.10 CBY43671.1 - 0.21 11.8 5.0 0.36 11.1 5.0 1.3 1 0 0 1 1 1 0 MamL-1 domain zf-C3HC PF07967.13 CBY43675.1 - 4e-17 62.5 0.4 3.2e-15 56.4 0.1 2.2 1 1 1 2 2 2 2 C3HC zinc finger-like MAPKK1_Int PF08923.10 CBY43676.1 - 1.7e-06 27.8 0.1 2.3e-06 27.4 0.1 1.2 1 1 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF4541 PF15074.6 CBY43677.1 - 1.6e-29 102.3 0.6 3.3e-29 101.3 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4541) Peptidase_S10 PF00450.22 CBY43678.1 - 0.068 12.6 0.4 0.12 11.7 0.4 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase zf-Mss51 PF13824.6 CBY43678.1 - 0.16 12.1 1.8 0.33 11.1 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4428 PF14471.6 CBY43678.1 - 0.16 11.9 5.6 1.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-HIT PF04438.16 CBY43678.1 - 0.24 11.3 3.4 0.16 11.9 1.0 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-B_box PF00643.24 CBY43678.1 - 0.48 10.6 7.2 7.8 6.7 0.5 3.3 3 0 0 3 3 3 0 B-box zinc finger zf-UBR PF02207.20 CBY43678.1 - 0.87 9.8 4.7 3 8.1 4.7 1.9 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF445 PF04286.12 CBY43679.1 - 0.00057 19.8 4.3 0.00094 19.1 4.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF445) DUF1641 PF07849.11 CBY43679.1 - 0.044 13.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) GerD PF17898.1 CBY43679.1 - 0.09 12.7 0.1 6.4 6.8 0.0 2.8 1 1 1 2 2 2 0 Spore germination GerD central core domain YtzH PF14165.6 CBY43679.1 - 0.3 11.5 3.4 11 6.5 0.2 3.5 1 1 3 4 4 4 0 YtzH-like protein Med20 PF08612.11 CBY43680.1 - 3.4e-23 82.2 0.1 4.1e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex PSCyt3 PF07627.11 CBY43680.1 - 0.081 13.2 0.1 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) MOZ_SAS PF01853.18 CBY43681.1 - 3.2e-79 264.7 0.3 4.8e-79 264.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY43681.1 - 5.5e-22 77.1 2.3 1.5e-21 75.8 2.3 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY43681.1 - 1.2e-20 73.1 0.2 2.9e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBY43681.1 - 0.00028 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY43681.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_16 PF05301.11 CBY43681.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Peptidase_S10 PF00450.22 CBY43683.1 - 0.067 12.6 0.4 0.12 11.7 0.4 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase zf-Mss51 PF13824.6 CBY43683.1 - 0.16 12.1 1.8 0.33 11.1 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4428 PF14471.6 CBY43683.1 - 0.16 11.9 5.6 1.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-HIT PF04438.16 CBY43683.1 - 0.24 11.3 3.4 0.16 11.9 1.0 1.9 2 0 0 2 2 2 0 HIT zinc finger zf-B_box PF00643.24 CBY43683.1 - 0.48 10.6 7.2 7.8 6.7 0.5 3.3 3 0 0 3 3 3 0 B-box zinc finger zf-UBR PF02207.20 CBY43683.1 - 0.87 9.8 4.7 3 8.1 4.7 1.9 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF445 PF04286.12 CBY43684.1 - 0.014 15.3 0.9 0.021 14.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1641 PF07849.11 CBY43684.1 - 0.016 15.0 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Med20 PF08612.11 CBY43685.1 - 2.6e-23 82.6 0.1 3.2e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex PSCyt3 PF07627.11 CBY43685.1 - 0.087 13.1 0.0 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) MOZ_SAS PF01853.18 CBY43686.1 - 3.2e-79 264.7 0.3 4.8e-79 264.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBY43686.1 - 5.5e-22 77.1 2.3 1.5e-21 75.8 2.3 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CBY43686.1 - 1.2e-20 73.1 0.2 2.9e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBY43686.1 - 0.00028 21.2 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBY43686.1 - 0.01 16.1 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_16 PF05301.11 CBY43686.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 PhoLip_ATPase_C PF16212.5 CBY43687.1 - 6e-70 235.8 19.7 6e-70 235.8 19.7 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBY43687.1 - 1.2e-19 69.7 0.1 5.9e-19 67.5 0.1 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBY43687.1 - 5.7e-11 42.3 2.2 9.8e-11 41.5 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBY43687.1 - 1.1e-10 41.5 0.2 5.3e-09 36.0 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBY43687.1 - 1.6e-10 41.7 0.2 0.00041 20.7 0.1 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBY43687.1 - 0.00093 19.0 0.2 0.0039 17.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1754 PF08555.10 CBY43688.1 - 3.9 8.3 15.5 7.4 7.4 15.5 1.5 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Motile_Sperm PF00635.26 CBY43689.1 - 6.3e-09 35.7 0.8 1.7e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 CBY43689.1 - 0.022 15.0 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DnaJ PF00226.31 CBY43690.1 - 3.1e-21 75.3 6.4 1.2e-20 73.4 2.9 2.8 2 0 0 2 2 2 1 DnaJ domain DUF5302 PF17227.2 CBY43690.1 - 0.044 14.8 0.2 0.044 14.8 0.2 5.5 5 0 0 5 5 5 0 Family of unknown function (DUF5302) Sdh_cyt PF01127.22 CBY43691.1 - 1.2e-16 60.8 5.7 1.5e-16 60.5 5.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TTL PF03133.15 CBY43692.1 - 3.1e-41 141.4 2.7 4.9e-41 140.8 2.7 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBY43692.1 - 1e-06 28.2 0.1 1.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 CBY43692.1 - 0.0036 16.9 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 CBY43692.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DHC_N2 PF08393.13 CBY43693.1 - 6.2e-63 213.3 12.9 6.2e-63 213.3 12.9 4.0 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CBY43693.1 - 6.7e-45 153.5 2.2 3.1e-25 88.9 0.1 4.5 2 1 2 4 4 4 3 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 CBY43693.1 - 3e-28 98.9 0.0 3e-28 98.9 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 CBY43693.1 - 3.1e-28 98.3 0.0 7e-26 90.7 0.0 3.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CBY43693.1 - 1.1e-27 96.7 0.1 1.1e-16 61.1 0.0 5.7 6 1 0 6 6 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 CBY43693.1 - 2.2e-25 89.4 10.1 5.5e-25 88.1 10.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CBY43693.1 - 1.5e-24 86.4 4.1 6.5e-24 84.3 0.8 3.7 3 1 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBY43693.1 - 9.7e-21 74.1 0.0 2.7e-15 56.3 0.0 4.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBY43693.1 - 2.5e-13 50.2 0.0 7.7e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CBY43693.1 - 8.3e-10 38.4 0.1 1.4e-08 34.3 0.0 3.1 2 1 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_22 PF13401.6 CBY43693.1 - 1.2e-08 35.3 0.0 0.79 10.0 0.0 5.5 4 0 0 4 4 4 3 AAA domain AAA PF00004.29 CBY43693.1 - 1.7e-07 31.8 1.1 0.47 10.9 0.0 5.7 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) DHC_N1 PF08385.12 CBY43693.1 - 5.5e-07 28.6 3.6 5.5e-07 28.6 3.6 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 CBY43693.1 - 3.4e-05 24.3 8.4 2.4 8.5 0.0 6.4 7 0 0 7 7 5 1 AAA ATPase domain KTI12 PF08433.10 CBY43693.1 - 0.00075 19.0 1.6 0.0027 17.2 0.0 2.8 3 0 0 3 3 3 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 CBY43693.1 - 0.0017 18.7 0.1 20 5.6 0.0 4.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 CBY43693.1 - 0.0051 17.4 4.1 6.9 7.2 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_28 PF13521.6 CBY43693.1 - 0.051 13.8 0.5 1.7 8.8 0.0 3.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 CBY43693.1 - 0.058 12.8 0.3 32 3.8 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI FAP206 PF12018.8 CBY43693.1 - 0.075 12.5 15.5 0.74 9.3 0.0 4.6 3 1 2 5 5 5 0 Domain of unknown function ABC_tran PF00005.27 CBY43693.1 - 0.13 12.7 14.0 3 8.4 0.0 5.8 5 0 0 5 5 5 0 ABC transporter AAA_24 PF13479.6 CBY43693.1 - 0.29 10.8 2.6 23 4.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain MIF4G PF02854.19 CBY43694.1 - 1.4e-06 28.2 0.1 1.6e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain IFRD PF05004.13 CBY43694.1 - 0.011 14.9 1.0 0.014 14.5 1.0 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Rab_eff_C PF04698.12 CBY43694.1 - 0.13 10.5 1.0 0.15 10.4 1.0 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus VGCC_beta4Aa_N PF12052.8 CBY43694.1 - 7.4 6.8 8.1 1 9.5 3.7 1.9 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF667 PF05018.13 CBY43695.1 - 8.6e-94 312.5 1.0 9.6e-94 312.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MIF4G_like_2 PF09090.11 CBY43696.1 - 9.7e-67 225.2 3.1 9.7e-67 225.2 3.1 1.5 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 CBY43696.1 - 1.8e-30 106.1 2.8 2.8e-30 105.5 1.0 2.2 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.19 CBY43696.1 - 8.6e-09 35.3 1.0 5.7e-08 32.7 0.0 2.7 3 0 0 3 3 3 1 MIF4G domain FAM219A PF15260.6 CBY43697.1 - 0.018 15.4 2.0 0.019 15.3 0.2 1.8 1 1 1 2 2 2 0 Protein family FAM219A MIF4G_like_2 PF09090.11 CBY43699.1 - 5e-67 226.2 3.1 9.5e-67 225.3 3.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 CBY43699.1 - 1.9e-30 106.1 2.9 2.9e-30 105.5 1.1 2.2 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.19 CBY43699.1 - 4.2e-08 33.1 1.2 2.6e-07 30.5 0.0 2.7 3 0 0 3 3 3 1 MIF4G domain FAM219A PF15260.6 CBY43700.1 - 0.085 13.2 0.2 0.085 13.2 0.2 2.2 2 1 1 3 3 3 0 Protein family FAM219A CD34_antigen PF06365.12 CBY43703.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family GAPT PF11770.8 CBY43703.1 - 0.067 13.0 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) FAM163 PF15069.6 CBY43703.1 - 0.072 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 FAM163 family Comm PF15957.5 CBY43703.1 - 0.13 12.6 0.1 0.65 10.3 0.1 2.0 2 0 0 2 2 2 0 Commissureless Vpu PF00558.19 CBY43703.1 - 0.19 11.5 0.8 5.6 6.8 0.2 2.5 2 0 0 2 2 2 0 Vpu protein MFS_1 PF07690.16 CBY43705.1 - 1.1e-05 24.6 19.1 0.00012 21.1 19.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily RNA_pol_Rpb1_3 PF04983.18 CBY43705.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Acetyltransf_1 PF00583.25 CBY43706.1 - 1.7e-14 54.1 0.0 2.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBY43706.1 - 6.8e-10 39.2 0.0 1.4e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBY43706.1 - 6.4e-07 29.4 0.0 1.8e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBY43706.1 - 4.2e-06 27.0 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CBY43706.1 - 0.00031 20.5 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 CBY43706.1 - 0.00033 20.6 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF5379 PF17350.2 CBY43706.1 - 0.056 13.7 1.1 0.1 12.9 1.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5379) Acetyltransf_15 PF17013.5 CBY43706.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase zf-RING_5 PF14634.6 CBY43707.1 - 3e-07 30.3 17.8 6.9e-07 29.1 17.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBY43707.1 - 3.9e-07 30.3 14.7 8.9e-07 29.2 14.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBY43707.1 - 7.8e-07 28.9 13.4 1.9e-06 27.6 13.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CBY43707.1 - 5.5e-06 26.1 11.9 1.6e-05 24.6 11.9 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CBY43707.1 - 8.8e-06 25.5 17.8 2.4e-05 24.1 17.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBY43707.1 - 3.6e-05 23.5 16.7 7.1e-05 22.6 16.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBY43707.1 - 0.0022 18.0 9.9 0.0025 17.8 8.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CBY43707.1 - 0.017 15.2 13.9 0.066 13.4 14.0 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBY43707.1 - 0.022 15.0 10.4 0.08 13.3 10.4 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CBY43707.1 - 0.032 14.1 13.0 0.07 13.0 13.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.21 CBY43707.1 - 1.1 9.4 16.1 11 6.3 16.1 2.5 1 1 0 1 1 1 0 FYVE zinc finger FemAB_like PF04339.12 CBY43707.1 - 1.8 7.6 6.8 0.72 8.9 3.7 1.7 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition HTH_19 PF12844.7 CBY43707.1 - 2.7 8.1 10.7 2.2 8.3 4.9 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain DUF262 PF03235.14 CBY43707.1 - 3.5 7.7 13.6 7 6.8 13.6 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF262 CUB PF00431.20 CBY43708.1 - 8.9e-05 22.8 0.4 0.00022 21.5 0.1 1.7 2 0 0 2 2 2 1 CUB domain Tmp39 PF10271.9 CBY43711.1 - 1.9e-36 126.0 11.4 2.5e-36 125.6 11.4 1.1 1 0 0 1 1 1 1 Putative transmembrane protein Thioredoxin PF00085.20 CBY43712.1 - 1.3e-74 246.7 1.0 5.1e-20 71.4 0.1 4.4 4 0 0 4 4 4 4 Thioredoxin DnaJ PF00226.31 CBY43712.1 - 3.6e-21 75.1 5.0 5.7e-21 74.4 3.8 2.0 2 0 0 2 2 2 1 DnaJ domain Thioredoxin_8 PF13905.6 CBY43712.1 - 1.3e-14 54.3 4.0 0.00046 20.5 0.0 6.4 4 4 2 6 6 6 3 Thioredoxin-like OST3_OST6 PF04756.13 CBY43712.1 - 1.8e-14 53.8 1.6 2.7e-06 26.9 0.1 3.7 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBY43712.1 - 1.7e-12 47.8 7.1 0.0039 17.6 0.0 5.7 4 2 0 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.21 CBY43712.1 - 1.2e-09 38.1 4.3 0.044 13.7 0.0 4.9 5 0 0 5 5 5 3 AhpC/TSA family Thioredoxin_3 PF13192.6 CBY43712.1 - 9.5e-09 35.2 0.3 0.12 12.4 0.0 3.9 3 0 0 3 3 3 3 Thioredoxin domain Thioredoxin_7 PF13899.6 CBY43712.1 - 1.9e-08 34.4 2.5 0.0077 16.4 0.1 4.5 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 CBY43712.1 - 3.4e-05 23.6 0.2 0.073 12.8 0.0 3.3 3 0 0 3 3 3 1 Redoxin Thioredoxin_6 PF13848.6 CBY43712.1 - 6.9e-05 22.8 0.0 0.72 9.7 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain TraF PF13728.6 CBY43712.1 - 0.00089 19.1 0.2 1.8 8.4 0.0 3.4 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBY43712.1 - 0.0081 15.9 0.2 0.74 9.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin GFO_IDH_MocA PF01408.22 CBY43713.1 - 2.3e-05 25.2 0.0 2.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-C2H2_4 PF13894.6 CBY43715.1 - 3.8e-09 36.6 72.3 0.027 15.3 1.0 11.9 11 2 0 11 11 11 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CBY43715.1 - 0.005 16.6 15.2 0.25 11.1 0.8 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2 PF00096.26 CBY43715.1 - 0.007 16.8 0.8 0.007 16.8 0.8 11.7 11 1 0 11 11 11 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBY43715.1 - 0.015 15.3 1.7 0.015 15.3 1.7 7.6 10 0 0 10 10 10 0 C2H2-type zinc finger zf-MYST PF17772.1 CBY43715.1 - 0.017 14.7 21.1 0.02 14.5 1.1 6.2 6 0 0 6 6 6 0 MYST family zinc finger domain Actin_micro PF17003.5 CBY43715.1 - 2.4 7.3 29.9 0.25 10.5 6.8 5.8 2 1 3 5 5 5 0 Putative actin-like family CLPTM1 PF05602.12 CBY43716.1 - 5.8e-134 447.3 1.2 7.3e-134 447.0 1.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CBY43716.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.0 3 0 0 3 3 3 0 PQ loop repeat Inositol_P PF00459.25 CBY43717.1 - 1.3e-08 34.7 0.0 1.4e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1754 PF08555.10 CBY43718.1 - 8.6e-05 23.3 16.3 8.6e-05 23.3 16.3 2.5 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) HA2 PF04408.23 CBY43720.1 - 1.7e-21 76.5 0.0 6.6e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY43720.1 - 7.4e-14 52.0 0.0 1.6e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY43720.1 - 0.02 14.7 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase ERO1 PF04137.15 CBY43722.1 - 6.1 5.9 9.3 5.5 6.1 3.4 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF2828 PF11443.8 CBY43722.1 - 8.6 4.3 13.0 0.072 11.2 5.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) BHD_1 PF10403.9 CBY43723.1 - 0.015 15.1 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 PGAP1 PF07819.13 CBY43724.1 - 2.4e-40 138.7 0.0 3.8e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CBY43724.1 - 4.8e-05 23.0 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CBY43724.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 CBY43724.1 - 6.8e-05 22.8 0.0 9.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CBY43724.1 - 6.9e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 CBY43724.1 - 0.00051 20.2 0.0 0.00092 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 CBY43724.1 - 0.0013 19.3 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CBY43724.1 - 0.0013 18.1 0.0 0.035 13.4 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 CBY43724.1 - 0.0045 16.5 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CBY43724.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 CBY43724.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 CBY43724.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_8 PF06259.12 CBY43724.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 CBY43724.1 - 0.053 13.0 0.3 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family YjbF PF11102.8 CBY43724.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF DIX PF00778.17 CBY43725.1 - 1.2e-07 31.5 0.0 5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 DIX domain Axin_b-cat_bind PF08833.10 CBY43725.1 - 0.0054 16.8 0.3 0.018 15.1 0.3 1.9 1 0 0 1 1 1 1 Axin beta-catenin binding domain MtlR PF05068.12 CBY43725.1 - 0.25 11.3 0.7 3.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Mannitol repressor Peptidase_S66 PF02016.15 CBY43726.1 - 0.045 13.9 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 LD-carboxypeptidase N-terminal domain AAA PF00004.29 CBY43727.1 - 1.9e-40 138.4 0.0 4.2e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBY43727.1 - 2e-19 69.3 0.2 4.2e-19 68.3 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBY43727.1 - 6.6e-10 38.6 0.3 1.8e-09 37.2 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBY43727.1 - 2.4e-05 24.5 0.0 5.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBY43727.1 - 4.2e-05 24.0 0.2 0.0054 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBY43727.1 - 0.0001 22.3 0.1 0.00068 19.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBY43727.1 - 0.0012 19.1 0.5 0.1 12.9 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBY43727.1 - 0.0046 16.4 0.2 0.033 13.6 0.1 2.3 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CBY43727.1 - 0.0048 16.4 0.1 0.048 13.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.12 CBY43727.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CBY43727.1 - 0.0089 15.2 0.0 0.028 13.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 CBY43727.1 - 0.0093 16.1 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBY43727.1 - 0.012 15.4 0.4 0.038 13.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBY43727.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CBY43727.1 - 0.035 13.9 1.2 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CBY43727.1 - 0.062 12.6 0.3 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 KaiC DUF1640 PF07798.11 CBY43727.1 - 0.095 12.7 1.0 0.17 11.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_7 PF12775.7 CBY43727.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBY43727.1 - 0.11 12.1 0.2 0.72 9.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Amidase PF01425.21 CBY43728.1 - 4.6e-73 246.7 0.0 1.6e-72 245.0 0.0 1.7 1 1 0 1 1 1 1 Amidase JUPITER PF17054.5 CBY43729.1 - 4.9e-05 23.0 1.4 0.00029 20.4 0.2 2.0 2 0 0 2 2 2 2 Microtubule-Associated protein Jupiter RCC1 PF00415.18 CBY43730.1 - 5.7e-25 87.7 7.6 2.8e-06 27.8 0.0 6.4 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY43730.1 - 2.1e-17 62.5 12.7 0.00085 19.1 0.2 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Methyltranf_PUA PF13636.6 CBY43730.1 - 0.035 14.1 0.0 8.9 6.4 0.0 2.7 3 0 0 3 3 3 0 RNA-binding PUA-like domain of methyltransferase RsmF HLH PF00010.26 CBY43731.1 - 6.7e-12 45.2 0.1 1.1e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RCC1 PF00415.18 CBY43732.1 - 4.4e-27 94.5 4.1 8.9e-06 26.2 0.0 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBY43732.1 - 5e-17 61.2 18.5 0.0017 18.1 0.2 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat HLH PF00010.26 CBY43733.1 - 6.1e-12 45.3 1.2 9.5e-12 44.7 0.2 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Dicty_REP PF05086.12 CBY43734.1 - 0.035 12.1 13.8 0.062 11.3 13.8 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.8 CBY43734.1 - 0.081 11.7 1.4 0.15 10.8 1.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRCC PF10253.9 CBY43734.1 - 2.1 9.1 9.1 4.7 8.0 9.1 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pex14_N PF04695.13 CBY43734.1 - 3.3 8.4 14.8 8.8 7.0 13.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rtf2 PF04641.12 CBY43735.1 - 0.064 12.6 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Rtf2 PF04641.12 CBY43736.1 - 2.5e-18 66.4 5.5 4.7e-18 65.5 5.5 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger adh_short PF00106.25 CBY43737.1 - 2.8e-39 134.6 0.1 3.8e-39 134.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBY43737.1 - 1.2e-26 93.8 0.1 3.1e-26 92.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBY43737.1 - 7.7e-06 25.9 0.3 3.1e-05 24.0 0.3 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBY43737.1 - 5e-05 22.9 0.0 0.00074 19.0 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBY43737.1 - 8.3e-05 22.6 0.0 0.00027 20.9 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CBY43737.1 - 0.00027 20.0 0.0 0.00059 18.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Rtf2 PF04641.12 CBY43738.1 - 7.3e-35 120.6 30.7 7.9e-33 113.9 30.7 3.1 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 CBY43738.1 - 0.003 17.5 1.5 0.0066 16.4 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBY43738.1 - 0.0045 16.8 2.7 0.0081 16.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 CBY43738.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Ndc1_Nup PF09531.10 CBY43738.1 - 0.65 8.6 8.7 1.1 7.9 8.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3HC4_4 PF15227.6 CBY43738.1 - 0.66 10.2 4.4 1.6 9.0 4.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UAA PF08449.11 CBY43739.1 - 1.3e-65 221.6 12.9 1.8e-65 221.2 12.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBY43739.1 - 0.00024 21.3 16.5 0.0093 16.1 10.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 CBY43739.1 - 0.023 13.0 4.8 0.031 12.6 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPT PF03151.16 CBY43739.1 - 0.041 13.2 6.8 0.076 12.4 6.8 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family RRM_1 PF00076.22 CBY43740.1 - 2.1e-07 30.6 0.0 3.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBY43740.1 - 0.0023 18.0 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CBY43740.1 - 0.066 13.4 0.1 0.37 11.0 0.1 2.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter GST_N_3 PF13417.6 CBY43740.1 - 0.092 13.2 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RRM_3 PF08777.11 CBY43741.1 - 1.4e-16 60.4 0.5 1.4e-16 60.4 0.5 2.4 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 CBY43741.1 - 2.7e-05 23.9 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBY43741.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Methyltransf_31 PF13847.6 CBY43742.1 - 3.6e-18 65.8 0.0 8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_3 PF08777.11 CBY43742.1 - 8.7e-17 61.0 0.3 3.3e-16 59.2 0.3 2.1 1 1 0 1 1 1 1 RNA binding motif Methyltransf_25 PF13649.6 CBY43742.1 - 1.3e-14 54.7 0.1 2.9e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY43742.1 - 7.1e-12 45.8 0.0 2.1e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY43742.1 - 8.2e-10 38.8 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY43742.1 - 1.4e-09 38.5 0.4 3.6e-09 37.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY43742.1 - 3.4e-06 26.6 0.0 7.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CBY43742.1 - 1.5e-05 24.4 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CBY43742.1 - 1.8e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RRM_1 PF00076.22 CBY43742.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NodS PF05401.11 CBY43742.1 - 7.1e-05 22.5 0.0 0.00017 21.2 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.13 CBY43742.1 - 0.00091 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBY43742.1 - 0.015 15.3 2.8 0.019 14.9 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain DREV PF05219.12 CBY43742.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 CBY43742.1 - 0.044 12.9 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 CBY43742.1 - 0.071 12.6 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 Putative methyltransferase Dimerisation2 PF16864.5 CBY43742.1 - 0.12 12.3 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_31 PF13847.6 CBY43743.1 - 3.7e-19 69.0 0.1 7.1e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBY43743.1 - 2.2e-15 57.1 0.1 6.7e-15 55.6 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBY43743.1 - 1.4e-12 48.0 0.1 3.8e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBY43743.1 - 9.8e-12 45.0 0.0 1.6e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBY43743.1 - 5e-10 40.0 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBY43743.1 - 8.8e-07 28.5 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CBY43743.1 - 1.3e-06 27.9 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CBY43743.1 - 8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CBY43743.1 - 3.2e-05 23.7 0.0 9.9e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.13 CBY43743.1 - 0.00035 20.1 0.0 0.00068 19.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBY43743.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBY43743.1 - 0.0037 18.3 0.0 0.0083 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CBY43743.1 - 0.009 15.1 0.0 0.018 14.2 0.0 1.4 2 0 0 2 2 2 1 DREV methyltransferase RrnaAD PF00398.20 CBY43743.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 CBY43743.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.6 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Dimerisation2 PF16864.5 CBY43743.1 - 0.043 13.8 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain Methyltransf_4 PF02390.17 CBY43743.1 - 0.043 13.3 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF3122 PF11320.8 CBY43744.1 - 0.081 13.0 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) DUF1664 PF07889.12 CBY43744.1 - 0.35 10.9 3.8 3.4 7.7 1.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BST2 PF16716.5 CBY43744.1 - 3.7 8.2 5.5 2.8 8.6 0.4 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SET PF00856.28 CBY43745.1 - 7e-14 52.6 7.0 9.3e-14 52.2 0.0 3.3 2 2 0 2 2 2 1 SET domain zf_C2H2_ZHX PF18387.1 CBY43748.1 - 0.00046 19.8 6.3 0.38 10.4 0.3 3.3 2 1 1 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CBY43748.1 - 0.0005 20.4 6.6 0.55 10.6 0.1 3.3 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CBY43748.1 - 0.0027 18.0 9.1 0.19 12.0 0.2 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CBY43748.1 - 0.0044 16.8 13.7 0.73 9.6 0.7 4.3 3 2 1 4 4 4 3 C2H2-type zinc-finger domain AKAP95 PF04988.12 CBY43748.1 - 0.076 13.2 11.9 0.41 10.9 0.3 3.2 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF4666 PF15697.5 CBY43748.1 - 0.15 12.7 1.1 0.38 11.4 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) zf-C2H2_4 PF13894.6 CBY43748.1 - 0.53 11.3 18.0 1.2 10.1 0.3 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger OrsD PF12013.8 CBY43748.1 - 0.88 10.0 6.5 1.3 9.5 0.1 2.9 3 1 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D SEP PF08059.13 CBY43749.1 - 9.5e-22 77.4 0.3 2.8e-21 75.9 0.1 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 CBY43749.1 - 1.4e-13 50.4 0.5 2.5e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain Tubulin PF00091.25 CBY43752.1 - 2.2e-68 230.3 0.0 3e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBY43752.1 - 1.8e-52 176.8 0.0 2.9e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBY43752.1 - 0.00036 20.3 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Laminin_EGF PF00053.24 CBY43753.1 - 4.7e-08 33.1 44.7 8.4e-05 22.6 9.9 3.8 3 0 0 3 3 3 3 Laminin EGF domain DUF3877 PF12993.7 CBY43753.1 - 0.029 14.2 0.6 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) NADH-UOR_E PF16514.5 CBY43753.1 - 0.068 13.5 0.1 0.5 10.7 0.1 2.6 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E FliJ PF02050.16 CBY43753.1 - 0.35 11.1 9.3 2.4 8.4 0.4 4.0 3 1 0 3 3 3 0 Flagellar FliJ protein DUF4200 PF13863.6 CBY43753.1 - 1.8 9.0 16.9 0.042 14.3 1.4 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) DUF737 PF05300.11 CBY43753.1 - 9.2 6.6 14.8 6.7 7.0 8.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF737) Tubulin PF00091.25 CBY43754.1 - 0.0038 17.5 0.0 0.0038 17.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Kelch_6 PF13964.6 CBY43756.1 - 7.2e-06 26.1 2.2 0.00096 19.4 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CBY43756.1 - 2.7e-05 23.7 1.4 7.3e-05 22.3 0.3 2.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CBY43756.1 - 0.00095 19.0 0.2 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 1 Kelch motif MIP PF00230.20 CBY43757.1 - 5.4e-06 26.3 2.3 5.7e-06 26.2 2.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Corona_M PF01635.18 CBY43757.1 - 0.14 11.5 1.6 0.12 11.7 0.6 1.3 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Lipase PF00151.19 CBY43759.1 - 1.2e-91 307.5 6.5 1e-55 189.4 0.0 3.3 1 1 2 3 3 3 3 Lipase DUF900 PF05990.12 CBY43759.1 - 1.9e-08 34.1 0.8 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 CBY43759.1 - 6.8e-08 32.3 0.4 0.00041 20.0 0.0 2.8 2 1 0 3 3 3 2 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CBY43759.1 - 4.9e-06 26.5 0.0 0.051 13.5 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) DUF676 PF05057.14 CBY43759.1 - 7e-06 25.7 0.5 0.34 10.4 0.0 3.2 2 1 1 3 3 3 2 Putative serine esterase (DUF676) Thioesterase PF00975.20 CBY43759.1 - 8.5e-06 26.0 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 CBY43759.1 - 9.6e-05 23.1 0.9 0.76 10.3 0.0 3.1 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBY43759.1 - 0.00032 20.4 0.8 0.54 9.9 0.1 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 CBY43759.1 - 0.095 12.3 0.5 7.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase TERB2 PF15101.6 CBY43760.1 - 5.2 7.1 11.6 6.8 6.7 4.6 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 NADH-UOR_E PF16514.5 CBY43762.1 - 0.053 13.8 0.6 0.06 13.7 0.6 1.0 1 0 0 1 1 1 0 putative NADH-ubiquinone oxidoreductase chain E DnaJ_C PF01556.18 CBY43763.1 - 9.3e-32 110.2 0.3 1.2e-31 109.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBY43763.1 - 6.1e-27 93.5 0.9 8e-27 93.2 0.3 1.5 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBY43763.1 - 6.4e-13 48.9 20.8 1.1e-12 48.2 20.8 1.4 1 0 0 1 1 1 1 DnaJ central domain NfeD PF01957.18 CBY43763.1 - 0.32 11.4 1.0 9 6.7 0.2 2.8 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding E1-E2_ATPase PF00122.20 CBY43764.1 - 2.1e-54 183.8 3.3 2.3e-53 180.4 0.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBY43764.1 - 3.7e-39 134.3 6.7 3.7e-39 134.3 6.7 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBY43764.1 - 3.2e-21 76.6 2.4 3.1e-20 73.4 2.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBY43764.1 - 2.6e-20 72.3 0.2 6.1e-20 71.1 0.2 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBY43764.1 - 8e-16 57.5 0.2 3.5e-15 55.4 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBY43764.1 - 3e-07 30.5 3.3 1.2e-06 28.5 1.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBY43764.1 - 2.3e-05 24.9 0.0 0.00017 22.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OB_NTP_bind PF07717.16 CBY43765.1 - 3.5e-19 68.9 0.0 1.1e-18 67.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CBY43765.1 - 8.8e-19 67.8 0.1 2.2e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBY43765.1 - 6.6e-15 55.4 0.5 1.6e-14 54.2 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBY43765.1 - 2.6e-06 27.3 0.4 2.3e-05 24.2 0.4 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBY43765.1 - 0.0083 16.4 0.3 0.082 13.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CBY43765.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 CBY43765.1 - 0.048 12.7 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CBY43765.1 - 0.055 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBY43765.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBY43765.1 - 0.13 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 CBY43766.1 - 4.5e-16 58.9 0.5 0.094 13.6 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY43766.1 - 1.9e-05 24.8 0.0 0.28 11.5 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L28e PF01778.17 CBY43768.1 - 2.7e-36 124.8 0.8 2.7e-36 124.8 0.8 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CBY43768.1 - 2.6e-27 95.3 12.0 5.1e-27 94.4 12.0 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region Pkinase PF00069.25 CBY43769.1 - 4.9e-70 235.9 0.0 6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43769.1 - 3.6e-34 118.2 0.0 5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY43769.1 - 9.8e-07 28.3 0.5 1.6e-06 27.6 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBY43769.1 - 9.9e-05 21.8 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBY43769.1 - 0.00075 19.5 0.1 0.0052 16.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBY43769.1 - 0.0047 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBY43769.1 - 0.024 14.2 0.1 0.049 13.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBY43770.1 - 2.3e-61 207.5 0.1 3e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43770.1 - 2.3e-29 102.5 0.0 3.5e-29 101.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBY43770.1 - 3.8e-06 26.4 0.1 6.6e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBY43770.1 - 3.3e-05 23.9 0.2 0.018 14.9 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBY43770.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 CBY43770.1 - 0.0012 17.9 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 CBY43770.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1160 PF06648.11 CBY43770.1 - 0.11 12.5 0.8 0.71 9.9 0.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) PDZ PF00595.24 CBY43771.1 - 1.5e-54 182.3 4.8 5.3e-18 65.2 0.5 3.5 3 0 0 3 3 3 3 PDZ domain Guanylate_kin PF00625.21 CBY43771.1 - 7.8e-50 169.1 0.1 1.8e-49 167.9 0.1 1.7 1 0 0 1 1 1 1 Guanylate kinase PDZ_6 PF17820.1 CBY43771.1 - 2e-23 82.0 0.2 6.3e-08 32.3 0.0 3.8 3 0 0 3 3 3 3 PDZ domain L27_1 PF09058.10 CBY43771.1 - 6.5e-19 67.7 3.1 1.3e-18 66.7 0.4 2.3 2 0 0 2 2 2 1 L27_1 PDZ_2 PF13180.6 CBY43771.1 - 4.6e-18 65.3 0.5 9.6e-06 25.8 0.0 3.8 3 0 0 3 3 3 3 PDZ domain SH3_1 PF00018.28 CBY43771.1 - 5.9e-09 35.4 0.0 2.7e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CBY43771.1 - 9.7e-08 31.6 0.0 3.2e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CBY43771.1 - 0.024 14.5 0.0 0.24 11.3 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain Plant_zn_clust PF10533.9 CBY43771.1 - 4.9 7.2 5.9 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 Plant zinc cluster domain Cadherin_C PF01049.17 CBY43772.1 - 3e-36 124.9 0.7 6.6e-36 123.8 0.7 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region Cadherin PF00028.17 CBY43772.1 - 1.5e-29 102.2 2.4 1.9e-08 34.7 0.0 5.2 5 0 0 5 5 5 4 Cadherin domain Cadherin_3 PF16184.5 CBY43772.1 - 2.8e-06 27.3 1.5 0.1 12.6 0.0 4.7 4 0 0 4 4 4 2 Cadherin-like Big_9 PF17963.1 CBY43772.1 - 0.00036 21.2 3.8 0.0059 17.3 0.1 3.3 3 0 0 3 3 3 1 Bacterial Ig domain DUF4834 PF16118.5 CBY43772.1 - 0.036 15.0 0.1 1.2 10.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glyco_hydro_12 PF01670.16 CBY43772.1 - 0.053 13.5 0.1 0.088 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 ASFV_J13L PF05568.11 CBY43772.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Cadherin_4 PF17803.1 CBY43772.1 - 0.16 12.6 8.2 0.42 11.3 0.1 3.9 4 0 0 4 4 4 0 Bacterial cadherin-like domain SOBP PF15279.6 CBY43773.1 - 0.33 11.5 27.2 0.43 11.1 27.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MMR1 PF08505.10 CBY43773.1 - 0.34 11.2 10.7 0.43 10.8 10.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.22 CBY43773.1 - 1 8.5 6.4 1.3 8.2 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmodium_Vir PF05795.11 CBY43773.1 - 1.6 8.1 7.7 2.2 7.6 7.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 CBY43773.1 - 1.7 7.4 18.1 2.2 7.0 18.1 1.1 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 CBY43773.1 - 6.5 5.1 32.8 9 4.7 32.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 CBY43773.1 - 8 3.4 12.2 11 3.0 12.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer fn3 PF00041.21 CBY43775.1 - 9.3e-06 25.9 0.0 0.0024 18.2 0.0 2.1 2 0 0 2 2 2 2 Fibronectin type III domain fn3 PF00041.21 CBY43776.1 - 2e-25 89.0 5.4 2.4e-06 27.8 0.1 5.4 5 0 0 5 5 5 5 Fibronectin type III domain Fibrinogen_C PF00147.18 CBY43776.1 - 4.7e-19 69.1 0.0 7.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain Interfer-bind PF09294.10 CBY43776.1 - 0.00038 20.7 7.9 2.6 8.4 0.0 5.3 4 1 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III DUF2369 PF10179.9 CBY43776.1 - 0.00098 19.5 3.8 0.86 10.0 0.2 4.6 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 CBY43776.1 - 0.0021 18.2 0.1 0.17 12.1 0.1 2.7 2 0 0 2 2 2 1 Fibronectin type III domain Glyco_hydro_36C PF16874.5 CBY43776.1 - 0.0025 18.3 0.0 5.1 7.6 0.0 4.4 5 1 0 5 5 5 1 Glycosyl hydrolase family 36 C-terminal domain Sec-ASP3 PF15432.6 CBY43776.1 - 0.0029 17.8 1.8 0.34 11.1 0.0 3.7 3 2 1 4 4 4 1 Accessory Sec secretory system ASP3 CarboxypepD_reg PF13620.6 CBY43776.1 - 0.0038 17.5 1.6 0.15 12.3 0.1 3.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Big_10 PF17964.1 CBY43776.1 - 0.036 14.1 0.1 2.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial Ig domain TQ PF18202.1 CBY43776.1 - 0.054 14.0 0.2 2.9 8.4 0.1 3.0 3 0 0 3 3 3 0 T-Q ester bond containing domain DUF2129 PF09902.9 CBY43776.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) Glutaminase PF04960.15 CBY43777.1 - 8.7e-92 307.3 0.3 1.2e-91 306.8 0.3 1.2 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 CBY43777.1 - 3.5e-11 43.5 0.0 7.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBY43777.1 - 1e-08 35.5 0.0 2e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBY43777.1 - 1.8e-06 28.1 0.0 5.2e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBY43777.1 - 0.00038 20.7 0.0 2.5 9.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CBY43777.1 - 0.14 12.6 0.0 7.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Pkinase PF00069.25 CBY43779.1 - 1.7e-10 40.7 0.2 4.1e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBY43779.1 - 0.0027 17.1 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Spb1_C PF07780.12 CBY43779.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Spb1 C-terminal domain IU_nuc_hydro PF01156.19 CBY43780.1 - 7.8e-50 170.2 0.0 9.8e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase COesterase PF00135.28 CBY43781.1 - 6.8e-94 315.6 0.0 1.8e-93 314.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CBY43781.1 - 5e-11 42.9 0.1 4.2e-10 39.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBY43781.1 - 0.00025 20.6 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MAR_sialic_bdg PF10564.9 CBY43782.1 - 3.9e-06 26.8 0.0 8.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat KAR9 PF08580.10 CBY43782.1 - 0.26 9.8 21.5 0.29 9.6 21.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Endomucin PF07010.12 CBY43782.1 - 0.55 10.2 33.2 0.67 9.9 33.2 1.1 1 0 0 1 1 1 0 Endomucin SOG2 PF10428.9 CBY43782.1 - 0.68 9.1 23.7 0.8 8.8 23.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 CBY43782.1 - 8.5 4.9 14.6 11 4.6 14.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.26 CBY43783.1 - 2.5e-39 135.4 0.8 3e-39 135.1 0.8 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 CBY43783.1 - 0.0084 17.0 0.1 0.013 16.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DnaJ PF00226.31 CBY43784.1 - 8.3e-16 57.9 1.4 8.3e-16 57.9 1.4 1.9 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 CBY43784.1 - 0.001 19.0 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 A repeated domain in UCH-protein GTP_EFTU PF00009.27 CBY43785.1 - 1.2e-32 113.1 0.2 1.9e-32 112.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBY43785.1 - 6.8e-07 29.4 0.1 1.7e-06 28.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBY43785.1 - 7.4e-07 29.5 0.2 2.3e-06 27.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 cobW PF02492.19 CBY43785.1 - 9e-05 22.1 2.6 0.00025 20.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CBY43785.1 - 0.00095 18.6 0.6 0.0022 17.5 0.3 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBY43785.1 - 0.0011 18.4 0.5 0.0025 17.2 0.5 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBY43785.1 - 0.0018 17.5 2.8 0.46 9.6 0.4 2.5 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 CBY43785.1 - 0.0022 17.5 0.3 0.0077 15.7 0.3 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.18 CBY43785.1 - 0.026 13.8 0.7 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 CBY43785.1 - 0.045 13.5 0.5 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CBY43785.1 - 0.064 13.2 0.2 0.064 13.2 0.2 2.4 3 0 0 3 3 3 0 RsgA GTPase ATP_bind_1 PF03029.17 CBY43785.1 - 0.14 11.9 2.7 9.6 5.9 0.1 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ufd2P_core PF10408.9 CBY43786.1 - 2.8e-148 495.3 22.3 3.4e-148 495.1 22.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CBY43786.1 - 5.3e-23 81.0 0.6 1.8e-22 79.3 0.2 2.3 2 0 0 2 2 2 1 U-box domain Init_tRNA_PT PF04179.12 CBY43786.1 - 0.11 12.8 0.8 12 6.2 0.4 2.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain His_Phos_2 PF00328.22 CBY43787.1 - 5.6e-09 35.8 0.0 1.7e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) 7tm_1 PF00001.21 CBY43788.1 - 7.8e-09 35.2 9.0 1.9e-08 34.0 4.5 2.8 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.6 CBY43788.1 - 0.48 10.7 14.6 0.26 11.6 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) 7tm_2 PF00002.24 CBY43789.1 - 1.6e-52 178.2 9.5 2.5e-52 177.6 9.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CBY43789.1 - 6.1e-07 28.9 8.9 1.3e-06 27.8 8.9 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LRRC37AB_C PF14914.6 CBY43789.1 - 0.12 12.3 0.7 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF3671 PF12420.8 CBY43789.1 - 2.6 8.1 7.4 3.2 7.8 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF1041 PF06292.17 CBY43790.1 - 4.1e-17 62.5 0.8 4.1e-17 62.5 0.8 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1041) PH PF00169.29 CBY43790.1 - 3.3e-08 34.0 0.1 8.4e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 PH domain C2 PF00168.30 CBY43790.1 - 0.0012 19.1 0.1 0.0029 17.9 0.1 1.7 1 0 0 1 1 1 1 C2 domain LXG PF04740.12 CBY43790.1 - 0.033 13.9 3.8 2.3 7.9 0.6 2.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily TMPIT PF07851.13 CBY43791.1 - 0.011 15.0 6.4 0.013 14.8 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 CBY43791.1 - 0.035 14.4 13.3 0.047 14.0 1.4 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 CBY43791.1 - 0.068 13.5 1.5 0.068 13.5 1.5 3.3 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KxDL PF10241.9 CBY43791.1 - 0.076 13.3 14.3 2.8 8.3 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 CBY43791.1 - 0.094 12.8 10.6 1.4 9.0 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 CBY43791.1 - 0.15 12.7 13.0 0.16 12.6 1.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Bacillus_HBL PF05791.11 CBY43791.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.8 CBY43791.1 - 0.25 11.6 14.6 0.17 12.1 12.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Snapin_Pallidin PF14712.6 CBY43791.1 - 0.29 11.6 9.8 0.4 11.1 7.7 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Tropomyosin_1 PF12718.7 CBY43791.1 - 0.41 10.8 19.7 0.32 11.1 8.9 2.2 1 1 1 2 2 2 0 Tropomyosin like Herpes_UL25 PF01499.16 CBY43791.1 - 0.53 8.7 5.9 0.67 8.4 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Atg14 PF10186.9 CBY43791.1 - 0.56 9.2 16.0 0.43 9.6 13.6 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2968 PF11180.8 CBY43791.1 - 1.3 8.7 14.8 1.6 8.3 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) BLOC1_2 PF10046.9 CBY43791.1 - 1.7 9.0 11.5 0.99 9.8 7.8 2.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 CBY43791.1 - 1.8 8.6 12.1 4.4 7.4 11.3 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 UPF0242 PF06785.11 CBY43791.1 - 2.2 8.4 17.2 2.6 8.1 15.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CBY43791.1 - 3.9 5.3 7.6 4.3 5.1 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.11 CBY43791.1 - 6.4 6.6 18.9 16 5.2 18.4 2.1 1 1 0 1 1 1 0 Phage minor structural protein GP20 Rx_N PF18052.1 CBY43791.1 - 10 6.5 12.5 1.7 8.9 0.2 2.9 1 1 2 3 3 3 0 Rx N-terminal domain Sulfotransfer_1 PF00685.27 CBY43793.1 - 5.5e-12 45.7 0.0 6.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 CBY43793.1 - 0.0018 18.2 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 CBY43793.1 - 0.052 13.9 0.0 9.4 6.5 0.0 2.4 2 1 1 3 3 3 0 Sulfotransferase family EKAL PF17986.1 CBY43793.1 - 0.054 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 EMP3-KAHRP-like N-terminal domain Mucin PF01456.17 CBY43793.1 - 0.22 11.5 0.0 0.32 11.0 0.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Sulfotransfer_1 PF00685.27 CBY43794.1 - 0.016 14.7 0.2 0.018 14.5 0.2 1.0 1 0 0 1 1 1 0 Sulfotransferase domain CRAL_TRIO PF00650.20 CBY43795.1 - 8.9e-26 90.5 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBY43795.1 - 2.8e-06 27.4 0.3 1.2e-05 25.4 0.2 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CHASE2 PF05226.11 CBY43795.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain Nmad5 PF18757.1 CBY43795.1 - 0.4 10.9 0.1 0.4 10.9 0.1 1.7 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Aa_trans PF01490.18 CBY43796.1 - 9.2e-63 212.3 30.3 5.2e-37 127.5 11.9 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein WD40 PF00400.32 CBY43797.1 - 6.2e-36 121.8 4.6 1.2e-09 38.7 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBY43797.1 - 1.2e-10 41.5 0.0 9.9e-05 22.6 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBY43797.1 - 6.1e-07 28.5 1.1 0.0081 14.9 0.0 4.0 1 1 1 3 3 3 3 Nucleoporin Nup120/160 HPS3_N PF14761.6 CBY43797.1 - 0.0024 17.5 0.0 0.4 10.2 0.0 3.3 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 Cytochrom_D1 PF02239.16 CBY43797.1 - 0.13 10.7 0.0 0.95 7.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Dor1 PF04124.12 CBY43798.1 - 4.9e-99 331.2 3.9 2.3e-98 329.0 3.4 1.9 2 0 0 2 2 2 1 Dor1-like family Vps51 PF08700.11 CBY43798.1 - 6.4e-06 26.2 0.0 3.3e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 CBY43798.1 - 0.0039 16.5 1.0 0.0071 15.7 0.3 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex PhoU PF01895.19 CBY43798.1 - 0.19 12.2 3.3 1.6 9.2 0.1 3.2 3 0 0 3 3 3 0 PhoU domain CPSase_L_D2 PF02786.17 CBY43799.1 - 6e-81 271.0 0.0 9.8e-81 270.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBY43799.1 - 4.7e-45 152.6 0.1 1.9e-44 150.7 0.1 2.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBY43799.1 - 9.7e-36 122.2 0.0 2.9e-35 120.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBY43799.1 - 1.4e-16 60.1 6.2 1.4e-16 60.1 2.6 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBY43799.1 - 1.2e-08 34.7 0.4 0.0011 18.7 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like PCC_BT PF18140.1 CBY43799.1 - 1.6e-08 34.9 0.0 4.2e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CBY43799.1 - 1.9e-08 34.1 0.3 4.1e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBY43799.1 - 1.9e-07 30.8 0.1 7.2e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBY43799.1 - 0.00076 19.6 0.1 0.0018 18.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CBY43799.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.6 CBY43799.1 - 0.0075 16.2 1.1 0.9 9.5 0.1 3.1 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 CBY43799.1 - 0.062 12.5 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 CBY43799.1 - 0.083 12.1 0.4 1.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBY43799.1 - 0.1 13.3 1.1 4.3 8.1 0.2 2.9 2 1 1 3 3 2 0 HlyD family secretion protein Aminotran_5 PF00266.19 CBY43800.1 - 1.4e-60 205.3 0.0 1.8e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBY43800.1 - 3.1e-06 26.6 0.0 2.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Scramblase PF03803.15 CBY43803.1 - 3e-67 226.2 0.0 4.3e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Scramblase P22_Cro PF14549.6 CBY43803.1 - 0.057 13.3 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Ig_3 PF13927.6 CBY43804.1 - 1e-24 86.9 2.9 4.3e-10 40.1 0.1 5.7 5 0 0 5 5 5 4 Immunoglobulin domain I-set PF07679.16 CBY43804.1 - 2.7e-23 81.9 1.0 1.2e-10 41.3 0.2 4.7 4 0 0 4 4 4 3 Immunoglobulin I-set domain Ig_2 PF13895.6 CBY43804.1 - 5.4e-18 65.1 2.3 3.5e-12 46.5 0.1 4.9 5 0 0 5 5 5 2 Immunoglobulin domain ig PF00047.25 CBY43804.1 - 1.7e-16 60.1 2.5 1.9e-05 24.7 0.2 4.0 3 0 0 3 3 3 3 Immunoglobulin domain V-set PF07686.17 CBY43804.1 - 4.6e-11 42.9 0.9 0.0005 20.2 0.0 4.8 4 1 1 5 5 5 3 Immunoglobulin V-set domain C2-set_2 PF08205.12 CBY43804.1 - 3.6e-09 36.6 1.1 1.4e-05 25.1 0.0 3.8 4 0 0 4 4 4 2 CD80-like C2-set immunoglobulin domain Ig_5 PF16681.5 CBY43804.1 - 3.9e-06 27.2 0.1 0.0012 19.2 0.0 3.6 3 0 0 3 3 3 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Ig_4 PF16680.5 CBY43804.1 - 5.5e-06 26.5 0.1 0.013 15.7 0.0 3.7 3 0 0 3 3 3 1 T-cell surface glycoprotein CD3 delta chain Ig_6 PF18452.1 CBY43804.1 - 0.00041 19.9 0.0 0.0034 16.9 0.0 2.4 2 0 0 2 2 2 1 Immunoglobulin domain C1-set PF07654.15 CBY43804.1 - 0.0017 18.7 1.0 4.7 7.7 0.0 5.1 6 0 0 6 6 6 1 Immunoglobulin C1-set domain C2-set PF05790.15 CBY43804.1 - 0.0036 17.5 0.2 0.44 10.8 0.1 2.8 2 0 0 2 2 2 1 Immunoglobulin C2-set domain Izumo-Ig PF16706.5 CBY43804.1 - 0.006 16.6 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 1 Izumo-like Immunoglobulin domain DUF1462 PF07315.11 CBY43806.1 - 0.076 13.3 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Nnf1 PF03980.14 CBY43806.1 - 0.1 13.0 0.1 0.1 13.0 0.1 1.3 1 1 0 1 1 1 0 Nnf1 Glyco_hydro_9 PF00759.19 CBY43807.1 - 7.6e-119 397.8 1.0 9.6e-119 397.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Syntaphilin PF15290.6 CBY43807.1 - 1.5 8.4 6.5 2.5 7.7 6.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Shugoshin_N PF07558.11 CBY43808.1 - 0.0015 18.3 1.9 0.0015 18.3 1.9 7.4 7 0 0 7 7 7 3 Shugoshin N-terminal coiled-coil region tRNA_synthFbeta PF17759.1 CBY43809.1 - 0.029 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain NHL PF01436.21 CBY43810.1 - 8.3e-05 22.4 0.1 0.033 14.2 0.0 3.7 4 0 0 4 4 4 2 NHL repeat HlyD_2 PF12700.7 CBY43814.1 - 0.19 10.5 6.8 0.3 9.8 6.8 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Complex1_LYR PF05347.15 CBY43815.1 - 0.0051 16.8 1.0 0.0064 16.5 1.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Acyltransferase PF01553.21 CBY43816.1 - 1.9e-09 37.3 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase F-box PF00646.33 CBY43817.1 - 0.00037 20.3 0.1 0.00073 19.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBY43817.1 - 0.0058 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF2723 PF11028.8 CBY43820.1 - 3.9e-24 85.5 4.2 9e-24 84.3 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) UPF0139 PF03669.13 CBY43820.1 - 0.096 12.6 0.2 0.096 12.6 0.2 2.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) DUF5453 PF17534.2 CBY43820.1 - 0.11 12.4 3.4 0.29 11.1 3.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Rrp15p PF07890.12 CBY43821.1 - 5.4e-18 65.6 8.6 7.7e-18 65.1 8.6 1.3 1 0 0 1 1 1 1 Rrp15p GSH_synth_ATP PF03917.17 CBY43823.1 - 4.8e-31 107.9 0.2 5.4e-31 107.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBY43823.1 - 1.7e-08 34.9 0.4 4.2e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Phospholip_B PF04916.13 CBY43823.1 - 0.025 13.2 0.1 0.042 12.4 0.1 1.2 1 0 0 1 1 1 0 Phospholipase B DUF3829 PF12889.7 CBY43823.1 - 0.059 12.9 3.5 0.72 9.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) GSH_synth_ATP PF03917.17 CBY43824.1 - 3.2e-34 118.3 0.0 3.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBY43824.1 - 4.2e-07 30.3 0.1 9.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Med31 PF05669.12 CBY43824.1 - 0.041 13.9 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 SOH1 DUF3903 PF13043.6 CBY43825.1 - 0.45 10.3 1.5 7.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) PX PF00787.24 CBY43826.1 - 1.2e-25 89.7 0.2 1.4e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 PX domain ZT_dimer PF16916.5 CBY43826.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter CNOT1_TTP_bind PF16417.5 CBY43827.1 - 0.044 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Helicase_IV_N PF12462.8 CBY43827.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Trypsin PF00089.26 CBY43828.1 - 1.8e-96 322.2 15.2 3.2e-53 180.8 1.8 2.8 3 0 0 3 3 3 2 Trypsin Trypsin_2 PF13365.6 CBY43828.1 - 3.8e-15 57.1 3.8 1.1e-06 29.6 0.0 3.4 2 1 1 3 3 3 2 Trypsin-like peptidase domain Peptidase_C4 PF00863.19 CBY43828.1 - 0.057 12.7 0.1 0.15 11.3 0.1 1.7 1 0 0 1 1 1 0 Peptidase family C4 DUF3439 PF11921.8 CBY43828.1 - 0.53 10.3 22.2 0.029 14.3 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 CBY43828.1 - 1.7 8.7 33.6 0.36 10.8 17.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 CBY43828.1 - 6.3 4.7 8.8 9.4 4.1 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 CBY43828.1 - 6.9 6.8 13.8 4.4 7.5 7.1 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Peptidase_M14 PF00246.24 CBY43829.1 - 6.6e-73 246.0 2.0 8.4e-73 245.7 2.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 CBY43829.1 - 3.9e-13 49.6 0.4 8.6e-13 48.5 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide SET PF00856.28 CBY43830.1 - 9.8e-11 42.3 0.0 2.9e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 SET domain Peptidase_M14 PF00246.24 CBY43831.1 - 7.1e-83 278.7 0.1 7.1e-83 278.7 0.1 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 CBY43831.1 - 1.6e-07 31.5 0.1 2.9e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CBY43831.1 - 4.5e-05 23.4 0.1 8.1e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 CBY43831.1 - 0.0058 15.8 0.3 0.028 13.5 0.3 2.0 2 1 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family TatD_DNase PF01026.21 CBY43835.1 - 9.4e-22 77.6 0.0 1.1e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Lectin_C PF00059.21 CBY43839.1 - 1.1e-18 67.9 6.4 1.9e-18 67.1 6.4 1.4 1 0 0 1 1 1 1 Lectin C-type domain F5_F8_type_C PF00754.25 CBY43839.1 - 7.2e-09 35.8 3.6 4.4e-07 30.1 0.3 2.6 2 1 0 2 2 2 1 F5/8 type C domain EF-hand_6 PF13405.6 CBY43840.1 - 2.2e-10 39.6 0.4 2.3e-06 27.1 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBY43840.1 - 4.3e-09 35.3 0.0 3.2e-05 23.2 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CBY43840.1 - 3.7e-08 33.7 0.0 0.00066 20.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBY43840.1 - 9.8e-05 21.7 1.6 0.00016 21.0 0.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CBY43840.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain Glyco_hydro_18 PF00704.28 CBY43842.1 - 6.4e-79 265.9 6.1 8.6e-79 265.5 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 CBY43842.1 - 2.5e-10 40.3 7.7 5.7e-10 39.2 7.7 1.6 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Defensin_RK-1 PF17860.1 CBY43842.1 - 0.7 10.4 2.6 0.95 10.0 0.5 2.2 2 0 0 2 2 2 0 RK-1-like defensin CD20 PF04103.15 CBY43845.1 - 0.00084 19.4 5.0 0.0011 19.0 5.0 1.2 1 0 0 1 1 1 1 CD20-like family Tetraspanin PF00335.20 CBY43845.1 - 0.029 14.1 12.4 0.045 13.4 12.4 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 CBY43845.1 - 3.5 8.1 9.0 70 4.0 8.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Lectin_C PF00059.21 CBY43846.1 - 5.1e-14 52.9 0.3 5.1e-14 52.9 0.3 2.3 3 0 0 3 3 3 1 Lectin C-type domain EGF_CA PF07645.15 CBY43846.1 - 3.6e-07 30.3 2.5 3.6e-07 30.3 2.5 3.4 2 1 1 3 3 3 1 Calcium-binding EGF domain DUF3439 PF11921.8 CBY43846.1 - 0.11 12.4 10.2 0.19 11.7 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CBY43846.1 - 0.18 10.0 8.6 0.24 9.5 8.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 2-oxoacid_dh PF00198.23 CBY43847.1 - 5.1e-77 258.4 0.0 6e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) VWA PF00092.28 CBY43849.1 - 5e-08 33.4 0.1 8.5e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain DUF3194 PF11419.8 CBY43850.1 - 0.15 12.5 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Kinesin PF00225.23 CBY43851.1 - 9.6e-115 383.0 0.1 9.6e-115 383.0 0.1 2.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBY43851.1 - 8.8e-22 77.6 0.1 3e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Saf_2TM PF18303.1 CBY43851.1 - 0.17 11.5 1.0 0.32 10.6 1.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Hema_stalk PF08720.10 CBY43851.1 - 0.17 11.5 0.5 0.41 10.3 0.5 1.6 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk zf-C2H2_aberr PF17017.5 CBY43851.1 - 0.43 10.7 4.8 0.37 10.9 1.5 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger Kinesin_assoc PF16183.5 CBY43851.1 - 0.73 10.0 9.0 15 5.7 8.8 2.7 1 1 0 1 1 1 0 Kinesin-associated Sedlin_N PF04628.13 CBY43853.1 - 2.4e-22 79.4 0.6 2.9e-22 79.2 0.6 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CBY43853.1 - 0.02 14.8 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Sybindin-like family DUF1131 PF06572.12 CBY43853.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) Pro_isomerase PF00160.21 CBY43854.1 - 1.9e-46 158.2 0.4 2.2e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amidase_2 PF01510.25 CBY43856.1 - 0.0011 19.5 0.5 0.0016 18.9 0.5 1.4 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase G-alpha PF00503.20 CBY43857.1 - 4.7e-79 266.1 6.7 5.7e-79 265.8 6.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CBY43857.1 - 1.1e-13 51.1 0.3 1.2e-11 44.4 0.1 2.2 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CBY43857.1 - 0.091 13.0 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PPR_2 PF13041.6 CBY43859.1 - 0.12 12.6 0.7 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 PPR repeat family TSP_1 PF00090.19 CBY43862.1 - 0.00043 20.4 1.9 0.0014 18.8 1.9 1.9 1 0 0 1 1 1 1 Thrombospondin type 1 domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20955v1/GCA_000209555.1_ASM20955v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20955v1/GCA_000209555.1_ASM20955v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20955v1/GCA_000209555.1_ASM20955v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Metazoa/Tunicata/Oikopleura_dioica-ASM20955v1/GCA_000209555.1_ASM20955v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 21:26:22 2019 # [ok]